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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Fusion gene:ATP2B4-OPTC (FusionGDB2 ID:HG493TG26254)

Fusion Gene Summary for ATP2B4-OPTC

check button Fusion gene summary
Fusion gene informationFusion gene name: ATP2B4-OPTC
Fusion gene ID: hg493tg26254
HgeneTgene
Gene symbol

ATP2B4

OPTC

Gene ID

493

26254

Gene nameATPase plasma membrane Ca2+ transporting 4opticin
SynonymsATP2B2|MXRA1|PMCA4|PMCA4b|PMCA4xOPT
Cytomap('ATP2B4')('OPTC')

1q32.1

1q32.1

Type of geneprotein-codingprotein-coding
Descriptionplasma membrane calcium-transporting ATPase 4ATPase, Ca++ transporting, plasma membrane 4matrix-remodeling-associated protein 1sarcolemmal calcium pumpopticinoculoglycan
Modification date2020032720200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000357681, ENST00000367218, 
ENST00000367219, ENST00000391954, 
ENST00000341360, ENST00000466407, 
Fusion gene scores* DoF score14 X 5 X 8=5601 X 3 X 2=6
# samples 173
** MAII scorelog2(17/560*10)=-1.71989208080726
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(3/6*10)=2.32192809488736
Context

PubMed: ATP2B4 [Title/Abstract] AND OPTC [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointATP2B4(203596347)-OPTC(203466105), # samples:2
Anticipated loss of major functional domain due to fusion event.ATP2B4-OPTC seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ATP2B4-OPTC seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneATP2B4

GO:0006874

cellular calcium ion homeostasis

19278978|25798335

HgeneATP2B4

GO:0010629

negative regulation of gene expression

25147342

HgeneATP2B4

GO:0010751

negative regulation of nitric oxide mediated signal transduction

19278978

HgeneATP2B4

GO:0016525

negative regulation of angiogenesis

25147342

HgeneATP2B4

GO:0033138

positive regulation of peptidyl-serine phosphorylation

19278978

HgeneATP2B4

GO:0043537

negative regulation of blood vessel endothelial cell migration

25147342

HgeneATP2B4

GO:0045019

negative regulation of nitric oxide biosynthetic process

11591728|19278978

HgeneATP2B4

GO:0051001

negative regulation of nitric-oxide synthase activity

11591728|17242280|19278978|19287093

HgeneATP2B4

GO:0070885

negative regulation of calcineurin-NFAT signaling cascade

19287093|25147342

HgeneATP2B4

GO:0071872

cellular response to epinephrine stimulus

19278978

HgeneATP2B4

GO:0098736

negative regulation of the force of heart contraction

17242280

HgeneATP2B4

GO:0140199

negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process

17242280

HgeneATP2B4

GO:1900082

negative regulation of arginine catabolic process

19278978

HgeneATP2B4

GO:1901660

calcium ion export

25798335

HgeneATP2B4

GO:1902548

negative regulation of cellular response to vascular endothelial growth factor stimulus

25147342

HgeneATP2B4

GO:1903078

positive regulation of protein localization to plasma membrane

15955804

HgeneATP2B4

GO:1903249

negative regulation of citrulline biosynthetic process

19278978

HgeneATP2B4

GO:2000481

positive regulation of cAMP-dependent protein kinase activity

19278978


check buttonFusion gene breakpoints across ATP2B4 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across OPTC (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4OVTCGA-25-1312-01AATP2B4chr1

203596347

+OPTCchr1

203466105

+
ChimerDB4OVTCGA-31-1950-01AATP2B4chr1

203596347

+OPTCchr1

203465093

+
ChimerDB4OVTCGA-31-1950-01AATP2B4chr1

203596347

+OPTCchr1

203466105

+
ChimerDB4SARCTCGA-DX-AB32-01AATP2B4chr1

203683405

-OPTCchr1

203472042

+


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Fusion Gene ORF analysis for ATP2B4-OPTC

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5UTR-3CDSENST00000357681ENST00000367222ATP2B4chr1

203596347

+OPTCchr1

203466105

+
5UTR-3CDSENST00000367218ENST00000367222ATP2B4chr1

203596347

+OPTCchr1

203466105

+
5UTR-3CDSENST00000367219ENST00000367222ATP2B4chr1

203596347

+OPTCchr1

203466105

+
5UTR-3CDSENST00000391954ENST00000367222ATP2B4chr1

203596347

+OPTCchr1

203466105

+
5UTR-5UTRENST00000357681ENST00000367222ATP2B4chr1

203596347

+OPTCchr1

203465093

+
5UTR-5UTRENST00000367218ENST00000367222ATP2B4chr1

203596347

+OPTCchr1

203465093

+
5UTR-5UTRENST00000367219ENST00000367222ATP2B4chr1

203596347

+OPTCchr1

203465093

+
5UTR-5UTRENST00000391954ENST00000367222ATP2B4chr1

203596347

+OPTCchr1

203465093

+
In-frameENST00000341360ENST00000367222ATP2B4chr1

203683405

-OPTCchr1

203472042

+
In-frameENST00000357681ENST00000367222ATP2B4chr1

203683405

-OPTCchr1

203472042

+
In-frameENST00000367218ENST00000367222ATP2B4chr1

203683405

-OPTCchr1

203472042

+
In-frameENST00000367219ENST00000367222ATP2B4chr1

203683405

-OPTCchr1

203472042

+
In-frameENST00000391954ENST00000367222ATP2B4chr1

203683405

-OPTCchr1

203472042

+
intron-3CDSENST00000341360ENST00000367222ATP2B4chr1

203596347

+OPTCchr1

203466105

+
intron-3CDSENST00000466407ENST00000367222ATP2B4chr1

203596347

+OPTCchr1

203466105

+
intron-3CDSENST00000466407ENST00000367222ATP2B4chr1

203683405

-OPTCchr1

203472042

+
intron-5UTRENST00000341360ENST00000367222ATP2B4chr1

203596347

+OPTCchr1

203465093

+
intron-5UTRENST00000466407ENST00000367222ATP2B4chr1

203596347

+OPTCchr1

203465093

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000357681ATP2B4chr1203683405-ENST00000367222OPTCchr1203472042+4040352910963795899
ENST00000391954ATP2B4chr1203683405-ENST00000367222OPTCchr1203472042+380132908573556899
ENST00000367218ATP2B4chr1203683405-ENST00000367222OPTCchr1203472042+380132908573556899
ENST00000367219ATP2B4chr1203683405-ENST00000367222OPTCchr1203472042+376532548573520887
ENST00000341360ATP2B4chr1203683405-ENST00000367222OPTCchr1203472042+331428033703069899

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000357681ENST00000367222ATP2B4chr1203683405-OPTCchr1203472042+0.0034545720.9965454
ENST00000391954ENST00000367222ATP2B4chr1203683405-OPTCchr1203472042+0.0032924430.99670756
ENST00000367218ENST00000367222ATP2B4chr1203683405-OPTCchr1203472042+0.0032924430.99670756
ENST00000367219ENST00000367222ATP2B4chr1203683405-OPTCchr1203472042+0.0037597870.99624026
ENST00000341360ENST00000367222ATP2B4chr1203683405-OPTCchr1203472042+0.0033365440.9966634

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Fusion Genomic Features for ATP2B4-OPTC


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
ATP2B4chr1203596347+OPTCchr1203466104+0.770465730.22953431
ATP2B4chr1203596347+OPTCchr1203465092+0.0134636770.9865363
ATP2B4chr1203596347+OPTCchr1203466104+0.770465730.22953431
ATP2B4chr1203596347+OPTCchr1203465092+0.0134636770.9865363

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for ATP2B4-OPTC


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr1:203596347/chr1:203466105)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneATP2B4chr1:203683405chr1:203472042ENST00000341360-1421114_1508021171.0Topological domainExtracellular
HgeneATP2B4chr1:203683405chr1:203472042ENST00000341360-1421172_3568021171.0Topological domainCytoplasmic
HgeneATP2B4chr1:203683405chr1:203472042ENST00000341360-14211_928021171.0Topological domainCytoplasmic
HgeneATP2B4chr1:203683405chr1:203472042ENST00000341360-1421377_4098021171.0Topological domainExtracellular
HgeneATP2B4chr1:203683405chr1:203472042ENST00000357681-1521114_1508021206.0Topological domainExtracellular
HgeneATP2B4chr1:203683405chr1:203472042ENST00000357681-1521172_3568021206.0Topological domainCytoplasmic
HgeneATP2B4chr1:203683405chr1:203472042ENST00000357681-15211_928021206.0Topological domainCytoplasmic
HgeneATP2B4chr1:203683405chr1:203472042ENST00000357681-1521377_4098021206.0Topological domainExtracellular
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367218-1522114_1508021171.0Topological domainExtracellular
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367218-1522172_3568021171.0Topological domainCytoplasmic
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367218-15221_928021171.0Topological domainCytoplasmic
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367218-1522377_4098021171.0Topological domainExtracellular
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367219-1421114_1507901159.0Topological domainExtracellular
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367219-1421172_3567901159.0Topological domainCytoplasmic
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367219-14211_927901159.0Topological domainCytoplasmic
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367219-1421377_4097901159.0Topological domainExtracellular
HgeneATP2B4chr1:203683405chr1:203472042ENST00000391954-1521114_1508021135.0Topological domainExtracellular
HgeneATP2B4chr1:203683405chr1:203472042ENST00000391954-1521172_3568021135.0Topological domainCytoplasmic
HgeneATP2B4chr1:203683405chr1:203472042ENST00000391954-15211_928021135.0Topological domainCytoplasmic
HgeneATP2B4chr1:203683405chr1:203472042ENST00000391954-1521377_4098021135.0Topological domainExtracellular
HgeneATP2B4chr1:203683405chr1:203472042ENST00000341360-1421151_1718021171.0TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000341360-1421357_3768021171.0TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000341360-1421410_4278021171.0TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000341360-142193_1138021171.0TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000357681-1521151_1718021206.0TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000357681-1521357_3768021206.0TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000357681-1521410_4278021206.0TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000357681-152193_1138021206.0TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367218-1522151_1718021171.0TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367218-1522357_3768021171.0TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367218-1522410_4278021171.0TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367218-152293_1138021171.0TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367219-1421151_1717901159.0TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367219-1421357_3767901159.0TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367219-1421410_4277901159.0TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367219-142193_1137901159.0TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000391954-1521151_1718021135.0TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000391954-1521357_3768021135.0TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000391954-1521410_4278021135.0TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000391954-152193_1138021135.0TransmembraneHelical
TgeneOPTCchr1:203683405chr1:203472042ENST0000036722248248_269244381.0RepeatNote=LRR 4
TgeneOPTCchr1:203683405chr1:203472042ENST0000036722248270_290244381.0RepeatNote=LRR 5
TgeneOPTCchr1:203683405chr1:203472042ENST0000036722248300_320244381.0RepeatNote=LRR 6

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneATP2B4chr1:203683405chr1:203472042ENST00000341360-14211086_11038021171.0RegionCalmodulin-binding subdomain A
HgeneATP2B4chr1:203683405chr1:203472042ENST00000341360-14211104_11138021171.0RegionCalmodulin-binding subdomain B
HgeneATP2B4chr1:203683405chr1:203472042ENST00000357681-15211086_11038021206.0RegionCalmodulin-binding subdomain A
HgeneATP2B4chr1:203683405chr1:203472042ENST00000357681-15211104_11138021206.0RegionCalmodulin-binding subdomain B
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367218-15221086_11038021171.0RegionCalmodulin-binding subdomain A
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367218-15221104_11138021171.0RegionCalmodulin-binding subdomain B
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367219-14211086_11037901159.0RegionCalmodulin-binding subdomain A
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367219-14211104_11137901159.0RegionCalmodulin-binding subdomain B
HgeneATP2B4chr1:203683405chr1:203472042ENST00000391954-15211086_11038021135.0RegionCalmodulin-binding subdomain A
HgeneATP2B4chr1:203683405chr1:203472042ENST00000391954-15211104_11138021135.0RegionCalmodulin-binding subdomain B
HgeneATP2B4chr1:203683405chr1:203472042ENST00000341360-14211016_10258021171.0Topological domainExtracellular
HgeneATP2B4chr1:203683405chr1:203472042ENST00000341360-14211048_12418021171.0Topological domainCytoplasmic
HgeneATP2B4chr1:203683405chr1:203472042ENST00000341360-1421428_8408021171.0Topological domainCytoplasmic
HgeneATP2B4chr1:203683405chr1:203472042ENST00000341360-1421861_8708021171.0Topological domainExtracellular
HgeneATP2B4chr1:203683405chr1:203472042ENST00000341360-1421892_9118021171.0Topological domainCytoplasmic
HgeneATP2B4chr1:203683405chr1:203472042ENST00000341360-1421935_9528021171.0Topological domainExtracellular
HgeneATP2B4chr1:203683405chr1:203472042ENST00000341360-1421975_9938021171.0Topological domainCytoplasmic
HgeneATP2B4chr1:203683405chr1:203472042ENST00000357681-15211016_10258021206.0Topological domainExtracellular
HgeneATP2B4chr1:203683405chr1:203472042ENST00000357681-15211048_12418021206.0Topological domainCytoplasmic
HgeneATP2B4chr1:203683405chr1:203472042ENST00000357681-1521428_8408021206.0Topological domainCytoplasmic
HgeneATP2B4chr1:203683405chr1:203472042ENST00000357681-1521861_8708021206.0Topological domainExtracellular
HgeneATP2B4chr1:203683405chr1:203472042ENST00000357681-1521892_9118021206.0Topological domainCytoplasmic
HgeneATP2B4chr1:203683405chr1:203472042ENST00000357681-1521935_9528021206.0Topological domainExtracellular
HgeneATP2B4chr1:203683405chr1:203472042ENST00000357681-1521975_9938021206.0Topological domainCytoplasmic
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367218-15221016_10258021171.0Topological domainExtracellular
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367218-15221048_12418021171.0Topological domainCytoplasmic
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367218-1522428_8408021171.0Topological domainCytoplasmic
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367218-1522861_8708021171.0Topological domainExtracellular
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367218-1522892_9118021171.0Topological domainCytoplasmic
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367218-1522935_9528021171.0Topological domainExtracellular
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367218-1522975_9938021171.0Topological domainCytoplasmic
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367219-14211016_10257901159.0Topological domainExtracellular
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367219-14211048_12417901159.0Topological domainCytoplasmic
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367219-1421428_8407901159.0Topological domainCytoplasmic
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367219-1421861_8707901159.0Topological domainExtracellular
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367219-1421892_9117901159.0Topological domainCytoplasmic
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367219-1421935_9527901159.0Topological domainExtracellular
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367219-1421975_9937901159.0Topological domainCytoplasmic
HgeneATP2B4chr1:203683405chr1:203472042ENST00000391954-15211016_10258021135.0Topological domainExtracellular
HgeneATP2B4chr1:203683405chr1:203472042ENST00000391954-15211048_12418021135.0Topological domainCytoplasmic
HgeneATP2B4chr1:203683405chr1:203472042ENST00000391954-1521428_8408021135.0Topological domainCytoplasmic
HgeneATP2B4chr1:203683405chr1:203472042ENST00000391954-1521861_8708021135.0Topological domainExtracellular
HgeneATP2B4chr1:203683405chr1:203472042ENST00000391954-1521892_9118021135.0Topological domainCytoplasmic
HgeneATP2B4chr1:203683405chr1:203472042ENST00000391954-1521935_9528021135.0Topological domainExtracellular
HgeneATP2B4chr1:203683405chr1:203472042ENST00000391954-1521975_9938021135.0Topological domainCytoplasmic
HgeneATP2B4chr1:203683405chr1:203472042ENST00000341360-14211026_10478021171.0TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000341360-1421841_8608021171.0TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000341360-1421871_8918021171.0TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000341360-1421912_9348021171.0TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000341360-1421953_9748021171.0TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000341360-1421994_10158021171.0TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000357681-15211026_10478021206.0TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000357681-1521841_8608021206.0TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000357681-1521871_8918021206.0TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000357681-1521912_9348021206.0TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000357681-1521953_9748021206.0TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000357681-1521994_10158021206.0TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367218-15221026_10478021171.0TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367218-1522841_8608021171.0TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367218-1522871_8918021171.0TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367218-1522912_9348021171.0TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367218-1522953_9748021171.0TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367218-1522994_10158021171.0TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367219-14211026_10477901159.0TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367219-1421841_8607901159.0TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367219-1421871_8917901159.0TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367219-1421912_9347901159.0TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367219-1421953_9747901159.0TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367219-1421994_10157901159.0TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000391954-15211026_10478021135.0TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000391954-1521841_8608021135.0TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000391954-1521871_8918021135.0TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000391954-1521912_9348021135.0TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000391954-1521953_9748021135.0TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000391954-1521994_10158021135.0TransmembraneHelical
TgeneOPTCchr1:203683405chr1:203472042ENST0000036722248128_140244381.0Compositional biasNote=Cys-rich
TgeneOPTCchr1:203683405chr1:203472042ENST000003672224881_112244381.0Compositional biasNote=Ser/Thr-rich
TgeneOPTCchr1:203683405chr1:203472042ENST0000036722248116_153244381.0DomainNote=LRRNT
TgeneOPTCchr1:203683405chr1:203472042ENST0000036722248154_175244381.0RepeatNote=LRR 1
TgeneOPTCchr1:203683405chr1:203472042ENST0000036722248178_199244381.0RepeatNote=LRR 2
TgeneOPTCchr1:203683405chr1:203472042ENST0000036722248202_223244381.0RepeatNote=LRR 3


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Fusion Gene Sequence for ATP2B4-OPTC


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>7872_7872_1_ATP2B4-OPTC_ATP2B4_chr1_203683405_ENST00000341360_OPTC_chr1_203472042_ENST00000367222_length(transcript)=3314nt_BP=2803nt
GCTGGTTGTTGCTAAGGTTGCTGCCATGGTAACATGCACATCCTGTTTACACCTTCATCTGGGCAAGTTGGTCTAAGCTAGGAACCTACC
TACCCTGGACAACTACTATCATCACCACCTGGGGACACCAATCATCGTGACACGGAGTCCACCTTCCACTCAGTTCCCCCATCCTCTTCC
TCCTCTCGCTGCCAGACTTCATACGGAAGAAAGGATCTAGACTTCGGACGGCTACTCGGGAGCTTATTGCACAAGATATATTCAATCTAT
TCCCTCACTGGGCCCCCAGAGAAGCAAGAAGTAGGAAGAAGTTGAGACAGGGAGGCAGGAGACACTGGTCAGTTGAAGGGAAACGCTACA
TCTTCTCTGGTTGAGGGGCTTGGTAACAGCAGGCAAAATGACGAACCCATCAGACCGTGTCTTGCCTGCCAACTCGATGGCCGAGAGCCG
TGAAGGGGACTTTGGCTGCACAGTAATGGAACTGAGGAAGCTCATGGAGCTGCGTTCAAGGGATGCACTGACCCAGATTAATGTCCACTA
TGGAGGTGTACAGAATCTCTGCAGTAGACTGAAAACCTCCCCTGTGGAAGGTCTGTCTGGGAACCCTGCAGATCTGGAGAAACGTAGGCA
GGTGTTTGGACACAACGTGATCCCCCCCAAAAAGCCCAAGACTTTCTTAGAATTAGTGTGGGAAGCTCTTCAAGATGTCACGCTTATCAT
CCTGGAGATTGCAGCCATCATCTCCCTGGTCCTGTCCTTTTATCGCCCTGCTGGTGAAGAAAATGAACTGTGTGGTCAAGTCGCAACTAC
CCCAGAAGATGAAAATGAGGCACAAGCTGGCTGGATTGAGGGGGCAGCCATCCTTTTCTCAGTGATCATCGTGGTGTTAGTGACTGCCTT
TAATGATTGGAGCAAAGAGAAGCAATTCCGGGGGCTGCAGTGCCGCATTGAACAGGAGCAAAAGTTCTCCATCATCCGAAACGGTCAACT
CATCCAGCTCCCTGTGGCTGAGATTGTGGTTGGTGATATTGCCCAAGTCAAATACGGTGATCTGCTGCCTGCAGATGGAATCCTGATCCA
AGGGAATGATCTGAAGATTGATGAGAGCTCTCTGACAGGGGAATCTGACCATGTCAAGAAGTCCCTGGACAAAGACCCCATGTTGCTCTC
AGGGACCCATGTCATGGAAGGTTCTGGCCGGATGGTGGTGACAGCTGTTGGTGTCAACTCTCAGACTGGAATCATCCTTACTCTCTTGGG
GGTCAATGAGGATGACGAAGGGGAGAAAAAGAAGAAAGGTAAAAAACAAGGAGTCCCTGAAAATCGCAACAAAGCAAAGACCCAAGACGG
AGTGGCCCTGGAAATCCAGCCACTCAACAGCCAGGAGGGAATCGACAATGAGGAAAAGGACAAGAAGGCAGTCAAGGTGCCTAAAAAGGA
GAAGTCAGTGCTGCAGGGCAAGCTGACTCGCCTGGCTGTTCAGATTGGGAAAGCCGGTCTGCTCATGTCTGCTCTCACGGTTTTCATCCT
GATTCTATACTTTGTGATTGACAACTTTGTGATAAATCGCAGACCATGGCTCCCTGAGTGTACTCCCATCTACATCCAGTACTTTGTCAA
GTTCTTCATCATCGGCATCACTGTACTGGTGGTGGCTGTGCCAGAGGGGCTGCCTCTGGCTGTCACCATCTCACTGGCCTACTCTGTGAA
GAAAATGATGAAAGACAATAACCTAGTACGGCACTTGGATGCTTGTGAGACCATGGGCAACGCCACCGCCATCTGCTCTGATAAGACAGG
CACGTTGACCATGAACCGCATGACTGTGGTACAAGCTTATATTGGGGGCATCCATTACCGTCAAATCCCAAGCCCTGATGTCTTCCTGCC
CAAAGTCCTGGACCTCATTGTCAATGGCATTTCTATCAACAGTGCTTATACCTCCAAGATTCTGCCTCCAGAGAAGGAGGGAGGCCTGCC
TCGGCAGGTGGGCAACAAGACCGAGTGTGCTCTGCTAGGCTTTGTCACAGATCTGAAGCAGGATTATCAGGCTGTGCGTAATGAAGTGCC
CGAGGAGAAGCTCTACAAGGTGTACACCTTTAACTCAGTGCGCAAGTCAATGAGCACCGTCATCAGGAATCCCAACGGTGGCTTCCGTAT
GTACAGCAAGGGCGCCTCTGAGATCATCTTGCGCAAGTGTAATCGAATCCTGGACCGGAAAGGGGAAGCAGTGCCATTCAAGAATAAAGA
CAGAGATGATATGGTACGCACTGTCATCGAGCCCATGGCCTGTGATGGACTCCGGACTATCTGCATAGCTTACCGGGACTTCGATGACAC
AGAGCCCTCTTGGGACAATGAGAATGAGATCCTCACCGAACTGACCTGTATCGCGGTGGTGGGCATTGAGGACCCTGTGCGCCCAGAGGT
GCCAGATGCTATTGCCAAATGCAAACAAGCTGGCATTACTGTCAGAATGGTGACAGGTGACAACATCAACACAGCCCGGGCCATTGCCAC
CAAATGTGGCATTCTGACACCTGGGGATGACTTCCTGTGCTTAGAAGGCAAAGAATTCAACCGGCTCATCCGCAACGAGAAAGGCGAGGT
AGAGCAAGAAAAGCTGGACAAGATCTGGCCTAAGCTTCGGGTCCTGGCGCGATCTTCTCCCACTGACAAGCACACCCTGGTGAAAGGCAT
AATTGACAGCACTGTTGGGGAACACCGGCAGGTCGTGGCTGTCACTGGTGATGGCACAAATGACGGGCCTGCTCTGAAGAAAGCGGATGT
TGGTTTTGCCATGGCAATGGAGAAGCTGCAGTTCCTTTACCTGTCAGACAACCTGCTGGATTCTATCCCGGGGCCTTTGCCCCTGAGCCT
GCGCTCTGTACACCTGCAGAATAACCTGATAGAGACCATGCAGAGAGACGTCTTCTGTGACCCCGAGGAGCACAAACACACCCGCAGGCA
GCTGGAAGACATCCGCCTGGATGGCAACCCCATCAACCTCAGCCTCTTCCCCAGCGCCTACTTCTGCCTGCCTCGGCTCCCCATCGGCCG
CTTCACGTAGCTCGGAGCCCTTCCACTCCTCCCAGGTCATCTCTTGGACCAGCGGGCATCACATTCTCCAGCAGCCGCCATCTCACACGC
CTCCCTCCTGTGGCCGCCGGCAGCATGGACAAAGGTCTCCATGCAGGGGGAGGAGGCCTGCTTCTTTCCCCACAGCTCTCACGTCTCCCT
TCTCCCTGCGGGTGACAAAGAAGCCCAAGGACCACCTCCTTCCTGCCTCATTGTAATAAAATTCCCCACACTGA

>7872_7872_1_ATP2B4-OPTC_ATP2B4_chr1_203683405_ENST00000341360_OPTC_chr1_203472042_ENST00000367222_length(amino acids)=899AA_BP=811
MRGLVTAGKMTNPSDRVLPANSMAESREGDFGCTVMELRKLMELRSRDALTQINVHYGGVQNLCSRLKTSPVEGLSGNPADLEKRRQVFG
HNVIPPKKPKTFLELVWEALQDVTLIILEIAAIISLVLSFYRPAGEENELCGQVATTPEDENEAQAGWIEGAAILFSVIIVVLVTAFNDW
SKEKQFRGLQCRIEQEQKFSIIRNGQLIQLPVAEIVVGDIAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSLDKDPMLLSGTH
VMEGSGRMVVTAVGVNSQTGIILTLLGVNEDDEGEKKKKGKKQGVPENRNKAKTQDGVALEIQPLNSQEGIDNEEKDKKAVKVPKKEKSV
LQGKLTRLAVQIGKAGLLMSALTVFILILYFVIDNFVINRRPWLPECTPIYIQYFVKFFIIGITVLVVAVPEGLPLAVTISLAYSVKKMM
KDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQAYIGGIHYRQIPSPDVFLPKVLDLIVNGISINSAYTSKILPPEKEGGLPRQV
GNKTECALLGFVTDLKQDYQAVRNEVPEEKLYKVYTFNSVRKSMSTVIRNPNGGFRMYSKGASEIILRKCNRILDRKGEAVPFKNKDRDD
MVRTVIEPMACDGLRTICIAYRDFDDTEPSWDNENEILTELTCIAVVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCG
ILTPGDDFLCLEGKEFNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAVTGDGTNDGPALKKADVGFA
MAMEKLQFLYLSDNLLDSIPGPLPLSLRSVHLQNNLIETMQRDVFCDPEEHKHTRRQLEDIRLDGNPINLSLFPSAYFCLPRLPIGRFT

--------------------------------------------------------------
>7872_7872_2_ATP2B4-OPTC_ATP2B4_chr1_203683405_ENST00000357681_OPTC_chr1_203472042_ENST00000367222_length(transcript)=4040nt_BP=3529nt
CACCCTCACCCCTCCTCCACCCCTACTCAGCTTTCTATTCAACAAGTGAGAGCAAGGGCGGGGAAGAAAGCCGACAGGGGAGAGGATTGC
TTCCCTTTCTTTTCCCATTCCCCCTTAAGACGAACCAGGAAGTAACCGCAAGAATCGGGCCACCTTAACAGTAGAGTAATGGTTTGGCCT
CGCGCCAAGTCCCACCTCTGTTCCAGCTCCTGCTCCTCCCCTCTCTCTTCCCGCACTGCTTGGGGAGAGCTGGTGAGCAAGAGTCTGGCC
CGAGTTAGCTAGAGCTGTTGCCATGACAAGCATTTTCTTAAGAAAGCTCTGCTGTTGAGATCGTCCAAAGCTGGGGGCTGGGAGGGGGGG
CACGAACTTCGTGGGGCACCATCCCTCCGAAGAGAGCAAGATCAGAGACACCCGCCCAGCTCTCCTGCACCCTTTTTCTTTCAGGAACCT
GAGAGGTCCTTCCCATTGGAGGGGCAGGGGGAGGAGACCCAGCCCACTCCCCGGCCTTAGCCAGAAAGGCAAGAGAGCAAAGCCAGCGTC
TCTAGCTTGGTTGCCACACTGGGGAGACTGGTGGGTGGTCACCCCACCCTACCCTCATCCATGGAAACCCGGAGGGAGAGTCCCGCCTGA
AGAAACCTGGATCTTTGCTAGAAAGAGAGAGATCCAGTTGTCATCGGTATCCAGGAAGCTCTCCTCTTCCTCCTCCTGACGTCTACTACT
ACAGTTGCTGGTTGTTGCTAAGGTTGCTGCCATGGTAACATGCACATCCTGTTTACACCTTCATCTGGGCAAGTTGGTCTAAGCTAGGAA
CCTACCTACCCTGGACAACTACTATCATCACCACCTGGGGACACCAATCATCGTGACACGGAGTCCACCTTCCACTCAGTTCCCCCATCC
TCTTCCTCCTCTCGCTGCCAGACTTCATACGGAAGAAAGGATCTAGACTTCGGACGGCTACTCGGGAGCTTATTGCACAAGATATATTCA
ATCTATTCCCTCACTGGGCCCCCAGAGAAGCAAGAAGTAGGAAGAAGTTGAGACAGGGAGGCAGGAGACACTGGTCAGTTGAAGGGAAAC
GCTACATCTTCTCTGGTTGAGGGGCTTGGTAACAGCAGGCAAAATGACGAACCCATCAGACCGTGTCTTGCCTGCCAACTCGATGGCCGA
GAGCCGTGAAGGGGACTTTGGCTGCACAGTAATGGAACTGAGGAAGCTCATGGAGCTGCGTTCAAGGGATGCACTGACCCAGATTAATGT
CCACTATGGAGGTGTACAGAATCTCTGCAGTAGACTGAAAACCTCCCCTGTGGAAGGTCTGTCTGGGAACCCTGCAGATCTGGAGAAACG
TAGGCAGGTGTTTGGACACAACGTGATCCCCCCCAAAAAGCCCAAGACTTTCTTAGAATTAGTGTGGGAAGCTCTTCAAGATGTCACGCT
TATCATCCTGGAGATTGCAGCCATCATCTCCCTGGTCCTGTCCTTTTATCGCCCTGCTGGTGAAGAAAATGAACTGTGTGGTCAAGTCGC
AACTACCCCAGAAGATGAAAATGAGGCACAAGCTGGCTGGATTGAGGGGGCAGCCATCCTTTTCTCAGTGATCATCGTGGTGTTAGTGAC
TGCCTTTAATGATTGGAGCAAAGAGAAGCAATTCCGGGGGCTGCAGTGCCGCATTGAACAGGAGCAAAAGTTCTCCATCATCCGAAACGG
TCAACTCATCCAGCTCCCTGTGGCTGAGATTGTGGTTGGTGATATTGCCCAAGTCAAATACGGTGATCTGCTGCCTGCAGATGGAATCCT
GATCCAAGGGAATGATCTGAAGATTGATGAGAGCTCTCTGACAGGGGAATCTGACCATGTCAAGAAGTCCCTGGACAAAGACCCCATGTT
GCTCTCAGGGACCCATGTCATGGAAGGTTCTGGCCGGATGGTGGTGACAGCTGTTGGTGTCAACTCTCAGACTGGAATCATCCTTACTCT
CTTGGGGGTCAATGAGGATGACGAAGGGGAGAAAAAGAAGAAAGGTAAAAAACAAGGAGTCCCTGAAAATCGCAACAAAGCAAAGACCCA
AGACGGAGTGGCCCTGGAAATCCAGCCACTCAACAGCCAGGAGGGAATCGACAATGAGGAAAAGGACAAGAAGGCAGTCAAGGTGCCTAA
AAAGGAGAAGTCAGTGCTGCAGGGCAAGCTGACTCGCCTGGCTGTTCAGATTGGGAAAGCCGGTCTGCTCATGTCTGCTCTCACGGTTTT
CATCCTGATTCTATACTTTGTGATTGACAACTTTGTGATAAATCGCAGACCATGGCTCCCTGAGTGTACTCCCATCTACATCCAGTACTT
TGTCAAGTTCTTCATCATCGGCATCACTGTACTGGTGGTGGCTGTGCCAGAGGGGCTGCCTCTGGCTGTCACCATCTCACTGGCCTACTC
TGTGAAGAAAATGATGAAAGACAATAACCTAGTACGGCACTTGGATGCTTGTGAGACCATGGGCAACGCCACCGCCATCTGCTCTGATAA
GACAGGCACGTTGACCATGAACCGCATGACTGTGGTACAAGCTTATATTGGGGGCATCCATTACCGTCAAATCCCAAGCCCTGATGTCTT
CCTGCCCAAAGTCCTGGACCTCATTGTCAATGGCATTTCTATCAACAGTGCTTATACCTCCAAGATTCTGCCTCCAGAGAAGGAGGGAGG
CCTGCCTCGGCAGGTGGGCAACAAGACCGAGTGTGCTCTGCTAGGCTTTGTCACAGATCTGAAGCAGGATTATCAGGCTGTGCGTAATGA
AGTGCCCGAGGAGAAGCTCTACAAGGTGTACACCTTTAACTCAGTGCGCAAGTCAATGAGCACCGTCATCAGGAATCCCAACGGTGGCTT
CCGTATGTACAGCAAGGGCGCCTCTGAGATCATCTTGCGCAAGTGTAATCGAATCCTGGACCGGAAAGGGGAAGCAGTGCCATTCAAGAA
TAAAGACAGAGATGATATGGTACGCACTGTCATCGAGCCCATGGCCTGTGATGGACTCCGGACTATCTGCATAGCTTACCGGGACTTCGA
TGACACAGAGCCCTCTTGGGACAATGAGAATGAGATCCTCACCGAACTGACCTGTATCGCGGTGGTGGGCATTGAGGACCCTGTGCGCCC
AGAGGTGCCAGATGCTATTGCCAAATGCAAACAAGCTGGCATTACTGTCAGAATGGTGACAGGTGACAACATCAACACAGCCCGGGCCAT
TGCCACCAAATGTGGCATTCTGACACCTGGGGATGACTTCCTGTGCTTAGAAGGCAAAGAATTCAACCGGCTCATCCGCAACGAGAAAGG
CGAGGTAGAGCAAGAAAAGCTGGACAAGATCTGGCCTAAGCTTCGGGTCCTGGCGCGATCTTCTCCCACTGACAAGCACACCCTGGTGAA
AGGCATAATTGACAGCACTGTTGGGGAACACCGGCAGGTCGTGGCTGTCACTGGTGATGGCACAAATGACGGGCCTGCTCTGAAGAAAGC
GGATGTTGGTTTTGCCATGGCAATGGAGAAGCTGCAGTTCCTTTACCTGTCAGACAACCTGCTGGATTCTATCCCGGGGCCTTTGCCCCT
GAGCCTGCGCTCTGTACACCTGCAGAATAACCTGATAGAGACCATGCAGAGAGACGTCTTCTGTGACCCCGAGGAGCACAAACACACCCG
CAGGCAGCTGGAAGACATCCGCCTGGATGGCAACCCCATCAACCTCAGCCTCTTCCCCAGCGCCTACTTCTGCCTGCCTCGGCTCCCCAT
CGGCCGCTTCACGTAGCTCGGAGCCCTTCCACTCCTCCCAGGTCATCTCTTGGACCAGCGGGCATCACATTCTCCAGCAGCCGCCATCTC
ACACGCCTCCCTCCTGTGGCCGCCGGCAGCATGGACAAAGGTCTCCATGCAGGGGGAGGAGGCCTGCTTCTTTCCCCACAGCTCTCACGT
CTCCCTTCTCCCTGCGGGTGACAAAGAAGCCCAAGGACCACCTCCTTCCTGCCTCATTGTAATAAAATTCCCCACACTGA

>7872_7872_2_ATP2B4-OPTC_ATP2B4_chr1_203683405_ENST00000357681_OPTC_chr1_203472042_ENST00000367222_length(amino acids)=899AA_BP=811
MRGLVTAGKMTNPSDRVLPANSMAESREGDFGCTVMELRKLMELRSRDALTQINVHYGGVQNLCSRLKTSPVEGLSGNPADLEKRRQVFG
HNVIPPKKPKTFLELVWEALQDVTLIILEIAAIISLVLSFYRPAGEENELCGQVATTPEDENEAQAGWIEGAAILFSVIIVVLVTAFNDW
SKEKQFRGLQCRIEQEQKFSIIRNGQLIQLPVAEIVVGDIAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSLDKDPMLLSGTH
VMEGSGRMVVTAVGVNSQTGIILTLLGVNEDDEGEKKKKGKKQGVPENRNKAKTQDGVALEIQPLNSQEGIDNEEKDKKAVKVPKKEKSV
LQGKLTRLAVQIGKAGLLMSALTVFILILYFVIDNFVINRRPWLPECTPIYIQYFVKFFIIGITVLVVAVPEGLPLAVTISLAYSVKKMM
KDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQAYIGGIHYRQIPSPDVFLPKVLDLIVNGISINSAYTSKILPPEKEGGLPRQV
GNKTECALLGFVTDLKQDYQAVRNEVPEEKLYKVYTFNSVRKSMSTVIRNPNGGFRMYSKGASEIILRKCNRILDRKGEAVPFKNKDRDD
MVRTVIEPMACDGLRTICIAYRDFDDTEPSWDNENEILTELTCIAVVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCG
ILTPGDDFLCLEGKEFNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAVTGDGTNDGPALKKADVGFA
MAMEKLQFLYLSDNLLDSIPGPLPLSLRSVHLQNNLIETMQRDVFCDPEEHKHTRRQLEDIRLDGNPINLSLFPSAYFCLPRLPIGRFT

--------------------------------------------------------------
>7872_7872_3_ATP2B4-OPTC_ATP2B4_chr1_203683405_ENST00000367218_OPTC_chr1_203472042_ENST00000367222_length(transcript)=3801nt_BP=3290nt
TTGGGGAGAGCTGGTGAGCAAGAGTCTGGCCCGAGTTAGCTAGAGCTGTTGCCATGACAAGCATTTTCTTAAGAAAGCTCTGCTGTTGAG
ATCGTCCAAAGCTGGGGGCTGGGAGGGGGGGCACGAACTTCGTGGGGCACCATCCCTCCGAAGAGAGCAAGATCAGAGACACCCGCCCAG
CTCTCCTGCACCCTTTTTCTTTCAGGAACCTGAGAGGTCCTTCCCATTGGAGGGGCAGGGGGAGGAGACCCAGCCCACTCCCCGGCCTTA
GCCAGAAAGGCAAGAGAGCAAAGCCAGCGTCTCTAGCTTGGTTGCCACACTGGGGAGACTGGTGGGTGGTCACCCCACCCTACCCTCATC
CATGGAAACCCGGAGGGAGAGTCCCGCCTGAAGAAACCTGGATCTTTGCTAGAAAGAGAGAGATCCAGTTGTCATCGGTATCCAGGAAGC
TCTCCTCTTCCTCCTCCTGACGTCTACTACTACAGTTGCTGGTTGTTGCTAAGGTTGCTGCCATGGTAACATGCACATCCTGTTTACACC
TTCATCTGGGCAAGTTGGTCTAAGCTAGGAACCTACCTACCCTGGACAACTACTATCATCACCACCTGGGGACACCAATCATCGTGACAC
GGAGTCCACCTTCCACTCAGTTCCCCCATCCTCTTCCTCCTCTCGCTGCCAGACTTCATACGGAAGAAAGGATCTAGACTTCGGACGGCT
ACTCGGGAGCTTATTGCACAAGATATATTCAATCTATTCCCTCACTGGGCCCCCAGAGAAGCAAGAAGTAGGAAGAAGTTGAGACAGGGA
GGCAGGAGACACTGGTCAGTTGAAGGGAAACGCTACATCTTCTCTGGTTGAGGGGCTTGGTAACAGCAGGCAAAATGACGAACCCATCAG
ACCGTGTCTTGCCTGCCAACTCGATGGCCGAGAGCCGTGAAGGGGACTTTGGCTGCACAGTAATGGAACTGAGGAAGCTCATGGAGCTGC
GTTCAAGGGATGCACTGACCCAGATTAATGTCCACTATGGAGGTGTACAGAATCTCTGCAGTAGACTGAAAACCTCCCCTGTGGAAGGTC
TGTCTGGGAACCCTGCAGATCTGGAGAAACGTAGGCAGGTGTTTGGACACAACGTGATCCCCCCCAAAAAGCCCAAGACTTTCTTAGAAT
TAGTGTGGGAAGCTCTTCAAGATGTCACGCTTATCATCCTGGAGATTGCAGCCATCATCTCCCTGGTCCTGTCCTTTTATCGCCCTGCTG
GTGAAGAAAATGAACTGTGTGGTCAAGTCGCAACTACCCCAGAAGATGAAAATGAGGCACAAGCTGGCTGGATTGAGGGGGCAGCCATCC
TTTTCTCAGTGATCATCGTGGTGTTAGTGACTGCCTTTAATGATTGGAGCAAAGAGAAGCAATTCCGGGGGCTGCAGTGCCGCATTGAAC
AGGAGCAAAAGTTCTCCATCATCCGAAACGGTCAACTCATCCAGCTCCCTGTGGCTGAGATTGTGGTTGGTGATATTGCCCAAGTCAAAT
ACGGTGATCTGCTGCCTGCAGATGGAATCCTGATCCAAGGGAATGATCTGAAGATTGATGAGAGCTCTCTGACAGGGGAATCTGACCATG
TCAAGAAGTCCCTGGACAAAGACCCCATGTTGCTCTCAGGGACCCATGTCATGGAAGGTTCTGGCCGGATGGTGGTGACAGCTGTTGGTG
TCAACTCTCAGACTGGAATCATCCTTACTCTCTTGGGGGTCAATGAGGATGACGAAGGGGAGAAAAAGAAGAAAGGTAAAAAACAAGGAG
TCCCTGAAAATCGCAACAAAGCAAAGACCCAAGACGGAGTGGCCCTGGAAATCCAGCCACTCAACAGCCAGGAGGGAATCGACAATGAGG
AAAAGGACAAGAAGGCAGTCAAGGTGCCTAAAAAGGAGAAGTCAGTGCTGCAGGGCAAGCTGACTCGCCTGGCTGTTCAGATTGGGAAAG
CCGGTCTGCTCATGTCTGCTCTCACGGTTTTCATCCTGATTCTATACTTTGTGATTGACAACTTTGTGATAAATCGCAGACCATGGCTCC
CTGAGTGTACTCCCATCTACATCCAGTACTTTGTCAAGTTCTTCATCATCGGCATCACTGTACTGGTGGTGGCTGTGCCAGAGGGGCTGC
CTCTGGCTGTCACCATCTCACTGGCCTACTCTGTGAAGAAAATGATGAAAGACAATAACCTAGTACGGCACTTGGATGCTTGTGAGACCA
TGGGCAACGCCACCGCCATCTGCTCTGATAAGACAGGCACGTTGACCATGAACCGCATGACTGTGGTACAAGCTTATATTGGGGGCATCC
ATTACCGTCAAATCCCAAGCCCTGATGTCTTCCTGCCCAAAGTCCTGGACCTCATTGTCAATGGCATTTCTATCAACAGTGCTTATACCT
CCAAGATTCTGCCTCCAGAGAAGGAGGGAGGCCTGCCTCGGCAGGTGGGCAACAAGACCGAGTGTGCTCTGCTAGGCTTTGTCACAGATC
TGAAGCAGGATTATCAGGCTGTGCGTAATGAAGTGCCCGAGGAGAAGCTCTACAAGGTGTACACCTTTAACTCAGTGCGCAAGTCAATGA
GCACCGTCATCAGGAATCCCAACGGTGGCTTCCGTATGTACAGCAAGGGCGCCTCTGAGATCATCTTGCGCAAGTGTAATCGAATCCTGG
ACCGGAAAGGGGAAGCAGTGCCATTCAAGAATAAAGACAGAGATGATATGGTACGCACTGTCATCGAGCCCATGGCCTGTGATGGACTCC
GGACTATCTGCATAGCTTACCGGGACTTCGATGACACAGAGCCCTCTTGGGACAATGAGAATGAGATCCTCACCGAACTGACCTGTATCG
CGGTGGTGGGCATTGAGGACCCTGTGCGCCCAGAGGTGCCAGATGCTATTGCCAAATGCAAACAAGCTGGCATTACTGTCAGAATGGTGA
CAGGTGACAACATCAACACAGCCCGGGCCATTGCCACCAAATGTGGCATTCTGACACCTGGGGATGACTTCCTGTGCTTAGAAGGCAAAG
AATTCAACCGGCTCATCCGCAACGAGAAAGGCGAGGTAGAGCAAGAAAAGCTGGACAAGATCTGGCCTAAGCTTCGGGTCCTGGCGCGAT
CTTCTCCCACTGACAAGCACACCCTGGTGAAAGGCATAATTGACAGCACTGTTGGGGAACACCGGCAGGTCGTGGCTGTCACTGGTGATG
GCACAAATGACGGGCCTGCTCTGAAGAAAGCGGATGTTGGTTTTGCCATGGCAATGGAGAAGCTGCAGTTCCTTTACCTGTCAGACAACC
TGCTGGATTCTATCCCGGGGCCTTTGCCCCTGAGCCTGCGCTCTGTACACCTGCAGAATAACCTGATAGAGACCATGCAGAGAGACGTCT
TCTGTGACCCCGAGGAGCACAAACACACCCGCAGGCAGCTGGAAGACATCCGCCTGGATGGCAACCCCATCAACCTCAGCCTCTTCCCCA
GCGCCTACTTCTGCCTGCCTCGGCTCCCCATCGGCCGCTTCACGTAGCTCGGAGCCCTTCCACTCCTCCCAGGTCATCTCTTGGACCAGC
GGGCATCACATTCTCCAGCAGCCGCCATCTCACACGCCTCCCTCCTGTGGCCGCCGGCAGCATGGACAAAGGTCTCCATGCAGGGGGAGG
AGGCCTGCTTCTTTCCCCACAGCTCTCACGTCTCCCTTCTCCCTGCGGGTGACAAAGAAGCCCAAGGACCACCTCCTTCCTGCCTCATTG
TAATAAAATTCCCCACACTGA

>7872_7872_3_ATP2B4-OPTC_ATP2B4_chr1_203683405_ENST00000367218_OPTC_chr1_203472042_ENST00000367222_length(amino acids)=899AA_BP=811
MRGLVTAGKMTNPSDRVLPANSMAESREGDFGCTVMELRKLMELRSRDALTQINVHYGGVQNLCSRLKTSPVEGLSGNPADLEKRRQVFG
HNVIPPKKPKTFLELVWEALQDVTLIILEIAAIISLVLSFYRPAGEENELCGQVATTPEDENEAQAGWIEGAAILFSVIIVVLVTAFNDW
SKEKQFRGLQCRIEQEQKFSIIRNGQLIQLPVAEIVVGDIAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSLDKDPMLLSGTH
VMEGSGRMVVTAVGVNSQTGIILTLLGVNEDDEGEKKKKGKKQGVPENRNKAKTQDGVALEIQPLNSQEGIDNEEKDKKAVKVPKKEKSV
LQGKLTRLAVQIGKAGLLMSALTVFILILYFVIDNFVINRRPWLPECTPIYIQYFVKFFIIGITVLVVAVPEGLPLAVTISLAYSVKKMM
KDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQAYIGGIHYRQIPSPDVFLPKVLDLIVNGISINSAYTSKILPPEKEGGLPRQV
GNKTECALLGFVTDLKQDYQAVRNEVPEEKLYKVYTFNSVRKSMSTVIRNPNGGFRMYSKGASEIILRKCNRILDRKGEAVPFKNKDRDD
MVRTVIEPMACDGLRTICIAYRDFDDTEPSWDNENEILTELTCIAVVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCG
ILTPGDDFLCLEGKEFNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAVTGDGTNDGPALKKADVGFA
MAMEKLQFLYLSDNLLDSIPGPLPLSLRSVHLQNNLIETMQRDVFCDPEEHKHTRRQLEDIRLDGNPINLSLFPSAYFCLPRLPIGRFT

--------------------------------------------------------------
>7872_7872_4_ATP2B4-OPTC_ATP2B4_chr1_203683405_ENST00000367219_OPTC_chr1_203472042_ENST00000367222_length(transcript)=3765nt_BP=3254nt
TTGGGGAGAGCTGGTGAGCAAGAGTCTGGCCCGAGTTAGCTAGAGCTGTTGCCATGACAAGCATTTTCTTAAGAAAGCTCTGCTGTTGAG
ATCGTCCAAAGCTGGGGGCTGGGAGGGGGGGCACGAACTTCGTGGGGCACCATCCCTCCGAAGAGAGCAAGATCAGAGACACCCGCCCAG
CTCTCCTGCACCCTTTTTCTTTCAGGAACCTGAGAGGTCCTTCCCATTGGAGGGGCAGGGGGAGGAGACCCAGCCCACTCCCCGGCCTTA
GCCAGAAAGGCAAGAGAGCAAAGCCAGCGTCTCTAGCTTGGTTGCCACACTGGGGAGACTGGTGGGTGGTCACCCCACCCTACCCTCATC
CATGGAAACCCGGAGGGAGAGTCCCGCCTGAAGAAACCTGGATCTTTGCTAGAAAGAGAGAGATCCAGTTGTCATCGGTATCCAGGAAGC
TCTCCTCTTCCTCCTCCTGACGTCTACTACTACAGTTGCTGGTTGTTGCTAAGGTTGCTGCCATGGTAACATGCACATCCTGTTTACACC
TTCATCTGGGCAAGTTGGTCTAAGCTAGGAACCTACCTACCCTGGACAACTACTATCATCACCACCTGGGGACACCAATCATCGTGACAC
GGAGTCCACCTTCCACTCAGTTCCCCCATCCTCTTCCTCCTCTCGCTGCCAGACTTCATACGGAAGAAAGGATCTAGACTTCGGACGGCT
ACTCGGGAGCTTATTGCACAAGATATATTCAATCTATTCCCTCACTGGGCCCCCAGAGAAGCAAGAAGTAGGAAGAAGTTGAGACAGGGA
GGCAGGAGACACTGGTCAGTTGAAGGGAAACGCTACATCTTCTCTGGTTGAGGGGCTTGGTAACAGCAGGCAAAATGACGAACCCATCAG
ACCGTGTCTTGCCTGCCAACTCGATGGCCGAGAGCCGTGAAGGGGACTTTGGCTGCACAGTAATGGAACTGAGGAAGCTCATGGAGCTGC
GTTCAAGGGATGCACTGACCCAGATTAATGTCCACTATGGAGGTGTACAGAATCTCTGCAGTAGACTGAAAACCTCCCCTGTGGAAGGTC
TGTCTGGGAACCCTGCAGATCTGGAGAAACGTAGGCAGGTGTTTGGACACAACGTGATCCCCCCCAAAAAGCCCAAGACTTTCTTAGAAT
TAGTGTGGGAAGCTCTTCAAGATGTCACGCTTATCATCCTGGAGATTGCAGCCATCATCTCCCTGGTCCTGTCCTTTTATCGCCCTGCTG
GTGAAGAAAATGAACTGTGTGGTCAAGTCGCAACTACCCCAGAAGATGAAAATGAGGCACAAGCTGGCTGGATTGAGGGGGCAGCCATCC
TTTTCTCAGTGATCATCGTGGTGTTAGTGACTGCCTTTAATGATTGGAGCAAAGAGAAGCAATTCCGGGGGCTGCAGTGCCGCATTGAAC
AGGAGCAAAAGTTCTCCATCATCCGAAACGGTCAACTCATCCAGCTCCCTGTGGCTGAGATTGTGGTTGGTGATATTGCCCAAGTCAAAT
ACGGTGATCTGCTGCCTGCAGATGGAATCCTGATCCAAGGGAATGATCTGAAGATTGATGAGAGCTCTCTGACAGGGGAATCTGACCATG
TCAAGAAGTCCCTGGACAAAGACCCCATGTTGCTCTCAGGGACCCATGTCATGGAAGGTTCTGGCCGGATGGTGGTGACAGCTGTTGGTG
TCAACTCTCAGACTGGAATCATCCTTACTCTCTTGGGGGTCAATGAGGATGACGAAGGGGAGAAAAAGAAGAAAGCAAAGACCCAAGACG
GAGTGGCCCTGGAAATCCAGCCACTCAACAGCCAGGAGGGAATCGACAATGAGGAAAAGGACAAGAAGGCAGTCAAGGTGCCTAAAAAGG
AGAAGTCAGTGCTGCAGGGCAAGCTGACTCGCCTGGCTGTTCAGATTGGGAAAGCCGGTCTGCTCATGTCTGCTCTCACGGTTTTCATCC
TGATTCTATACTTTGTGATTGACAACTTTGTGATAAATCGCAGACCATGGCTCCCTGAGTGTACTCCCATCTACATCCAGTACTTTGTCA
AGTTCTTCATCATCGGCATCACTGTACTGGTGGTGGCTGTGCCAGAGGGGCTGCCTCTGGCTGTCACCATCTCACTGGCCTACTCTGTGA
AGAAAATGATGAAAGACAATAACCTAGTACGGCACTTGGATGCTTGTGAGACCATGGGCAACGCCACCGCCATCTGCTCTGATAAGACAG
GCACGTTGACCATGAACCGCATGACTGTGGTACAAGCTTATATTGGGGGCATCCATTACCGTCAAATCCCAAGCCCTGATGTCTTCCTGC
CCAAAGTCCTGGACCTCATTGTCAATGGCATTTCTATCAACAGTGCTTATACCTCCAAGATTCTGCCTCCAGAGAAGGAGGGAGGCCTGC
CTCGGCAGGTGGGCAACAAGACCGAGTGTGCTCTGCTAGGCTTTGTCACAGATCTGAAGCAGGATTATCAGGCTGTGCGTAATGAAGTGC
CCGAGGAGAAGCTCTACAAGGTGTACACCTTTAACTCAGTGCGCAAGTCAATGAGCACCGTCATCAGGAATCCCAACGGTGGCTTCCGTA
TGTACAGCAAGGGCGCCTCTGAGATCATCTTGCGCAAGTGTAATCGAATCCTGGACCGGAAAGGGGAAGCAGTGCCATTCAAGAATAAAG
ACAGAGATGATATGGTACGCACTGTCATCGAGCCCATGGCCTGTGATGGACTCCGGACTATCTGCATAGCTTACCGGGACTTCGATGACA
CAGAGCCCTCTTGGGACAATGAGAATGAGATCCTCACCGAACTGACCTGTATCGCGGTGGTGGGCATTGAGGACCCTGTGCGCCCAGAGG
TGCCAGATGCTATTGCCAAATGCAAACAAGCTGGCATTACTGTCAGAATGGTGACAGGTGACAACATCAACACAGCCCGGGCCATTGCCA
CCAAATGTGGCATTCTGACACCTGGGGATGACTTCCTGTGCTTAGAAGGCAAAGAATTCAACCGGCTCATCCGCAACGAGAAAGGCGAGG
TAGAGCAAGAAAAGCTGGACAAGATCTGGCCTAAGCTTCGGGTCCTGGCGCGATCTTCTCCCACTGACAAGCACACCCTGGTGAAAGGCA
TAATTGACAGCACTGTTGGGGAACACCGGCAGGTCGTGGCTGTCACTGGTGATGGCACAAATGACGGGCCTGCTCTGAAGAAAGCGGATG
TTGGTTTTGCCATGGCAATGGAGAAGCTGCAGTTCCTTTACCTGTCAGACAACCTGCTGGATTCTATCCCGGGGCCTTTGCCCCTGAGCC
TGCGCTCTGTACACCTGCAGAATAACCTGATAGAGACCATGCAGAGAGACGTCTTCTGTGACCCCGAGGAGCACAAACACACCCGCAGGC
AGCTGGAAGACATCCGCCTGGATGGCAACCCCATCAACCTCAGCCTCTTCCCCAGCGCCTACTTCTGCCTGCCTCGGCTCCCCATCGGCC
GCTTCACGTAGCTCGGAGCCCTTCCACTCCTCCCAGGTCATCTCTTGGACCAGCGGGCATCACATTCTCCAGCAGCCGCCATCTCACACG
CCTCCCTCCTGTGGCCGCCGGCAGCATGGACAAAGGTCTCCATGCAGGGGGAGGAGGCCTGCTTCTTTCCCCACAGCTCTCACGTCTCCC
TTCTCCCTGCGGGTGACAAAGAAGCCCAAGGACCACCTCCTTCCTGCCTCATTGTAATAAAATTCCCCACACTGA

>7872_7872_4_ATP2B4-OPTC_ATP2B4_chr1_203683405_ENST00000367219_OPTC_chr1_203472042_ENST00000367222_length(amino acids)=887AA_BP=799
MRGLVTAGKMTNPSDRVLPANSMAESREGDFGCTVMELRKLMELRSRDALTQINVHYGGVQNLCSRLKTSPVEGLSGNPADLEKRRQVFG
HNVIPPKKPKTFLELVWEALQDVTLIILEIAAIISLVLSFYRPAGEENELCGQVATTPEDENEAQAGWIEGAAILFSVIIVVLVTAFNDW
SKEKQFRGLQCRIEQEQKFSIIRNGQLIQLPVAEIVVGDIAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSLDKDPMLLSGTH
VMEGSGRMVVTAVGVNSQTGIILTLLGVNEDDEGEKKKKAKTQDGVALEIQPLNSQEGIDNEEKDKKAVKVPKKEKSVLQGKLTRLAVQI
GKAGLLMSALTVFILILYFVIDNFVINRRPWLPECTPIYIQYFVKFFIIGITVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDAC
ETMGNATAICSDKTGTLTMNRMTVVQAYIGGIHYRQIPSPDVFLPKVLDLIVNGISINSAYTSKILPPEKEGGLPRQVGNKTECALLGFV
TDLKQDYQAVRNEVPEEKLYKVYTFNSVRKSMSTVIRNPNGGFRMYSKGASEIILRKCNRILDRKGEAVPFKNKDRDDMVRTVIEPMACD
GLRTICIAYRDFDDTEPSWDNENEILTELTCIAVVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFLCLE
GKEFNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAVTGDGTNDGPALKKADVGFAMAMEKLQFLYLS
DNLLDSIPGPLPLSLRSVHLQNNLIETMQRDVFCDPEEHKHTRRQLEDIRLDGNPINLSLFPSAYFCLPRLPIGRFT

--------------------------------------------------------------
>7872_7872_5_ATP2B4-OPTC_ATP2B4_chr1_203683405_ENST00000391954_OPTC_chr1_203472042_ENST00000367222_length(transcript)=3801nt_BP=3290nt
TTGGGGAGAGCTGGTGAGCAAGAGTCTGGCCCGAGTTAGCTAGAGCTGTTGCCATGACAAGCATTTTCTTAAGAAAGCTCTGCTGTTGAG
ATCGTCCAAAGCTGGGGGCTGGGAGGGGGGGCACGAACTTCGTGGGGCACCATCCCTCCGAAGAGAGCAAGATCAGAGACACCCGCCCAG
CTCTCCTGCACCCTTTTTCTTTCAGGAACCTGAGAGGTCCTTCCCATTGGAGGGGCAGGGGGAGGAGACCCAGCCCACTCCCCGGCCTTA
GCCAGAAAGGCAAGAGAGCAAAGCCAGCGTCTCTAGCTTGGTTGCCACACTGGGGAGACTGGTGGGTGGTCACCCCACCCTACCCTCATC
CATGGAAACCCGGAGGGAGAGTCCCGCCTGAAGAAACCTGGATCTTTGCTAGAAAGAGAGAGATCCAGTTGTCATCGGTATCCAGGAAGC
TCTCCTCTTCCTCCTCCTGACGTCTACTACTACAGTTGCTGGTTGTTGCTAAGGTTGCTGCCATGGTAACATGCACATCCTGTTTACACC
TTCATCTGGGCAAGTTGGTCTAAGCTAGGAACCTACCTACCCTGGACAACTACTATCATCACCACCTGGGGACACCAATCATCGTGACAC
GGAGTCCACCTTCCACTCAGTTCCCCCATCCTCTTCCTCCTCTCGCTGCCAGACTTCATACGGAAGAAAGGATCTAGACTTCGGACGGCT
ACTCGGGAGCTTATTGCACAAGATATATTCAATCTATTCCCTCACTGGGCCCCCAGAGAAGCAAGAAGTAGGAAGAAGTTGAGACAGGGA
GGCAGGAGACACTGGTCAGTTGAAGGGAAACGCTACATCTTCTCTGGTTGAGGGGCTTGGTAACAGCAGGCAAAATGACGAACCCATCAG
ACCGTGTCTTGCCTGCCAACTCGATGGCCGAGAGCCGTGAAGGGGACTTTGGCTGCACAGTAATGGAACTGAGGAAGCTCATGGAGCTGC
GTTCAAGGGATGCACTGACCCAGATTAATGTCCACTATGGAGGTGTACAGAATCTCTGCAGTAGACTGAAAACCTCCCCTGTGGAAGGTC
TGTCTGGGAACCCTGCAGATCTGGAGAAACGTAGGCAGGTGTTTGGACACAACGTGATCCCCCCCAAAAAGCCCAAGACTTTCTTAGAAT
TAGTGTGGGAAGCTCTTCAAGATGTCACGCTTATCATCCTGGAGATTGCAGCCATCATCTCCCTGGTCCTGTCCTTTTATCGCCCTGCTG
GTGAAGAAAATGAACTGTGTGGTCAAGTCGCAACTACCCCAGAAGATGAAAATGAGGCACAAGCTGGCTGGATTGAGGGGGCAGCCATCC
TTTTCTCAGTGATCATCGTGGTGTTAGTGACTGCCTTTAATGATTGGAGCAAAGAGAAGCAATTCCGGGGGCTGCAGTGCCGCATTGAAC
AGGAGCAAAAGTTCTCCATCATCCGAAACGGTCAACTCATCCAGCTCCCTGTGGCTGAGATTGTGGTTGGTGATATTGCCCAAGTCAAAT
ACGGTGATCTGCTGCCTGCAGATGGAATCCTGATCCAAGGGAATGATCTGAAGATTGATGAGAGCTCTCTGACAGGGGAATCTGACCATG
TCAAGAAGTCCCTGGACAAAGACCCCATGTTGCTCTCAGGGACCCATGTCATGGAAGGTTCTGGCCGGATGGTGGTGACAGCTGTTGGTG
TCAACTCTCAGACTGGAATCATCCTTACTCTCTTGGGGGTCAATGAGGATGACGAAGGGGAGAAAAAGAAGAAAGGTAAAAAACAAGGAG
TCCCTGAAAATCGCAACAAAGCAAAGACCCAAGACGGAGTGGCCCTGGAAATCCAGCCACTCAACAGCCAGGAGGGAATCGACAATGAGG
AAAAGGACAAGAAGGCAGTCAAGGTGCCTAAAAAGGAGAAGTCAGTGCTGCAGGGCAAGCTGACTCGCCTGGCTGTTCAGATTGGGAAAG
CCGGTCTGCTCATGTCTGCTCTCACGGTTTTCATCCTGATTCTATACTTTGTGATTGACAACTTTGTGATAAATCGCAGACCATGGCTCC
CTGAGTGTACTCCCATCTACATCCAGTACTTTGTCAAGTTCTTCATCATCGGCATCACTGTACTGGTGGTGGCTGTGCCAGAGGGGCTGC
CTCTGGCTGTCACCATCTCACTGGCCTACTCTGTGAAGAAAATGATGAAAGACAATAACCTAGTACGGCACTTGGATGCTTGTGAGACCA
TGGGCAACGCCACCGCCATCTGCTCTGATAAGACAGGCACGTTGACCATGAACCGCATGACTGTGGTACAAGCTTATATTGGGGGCATCC
ATTACCGTCAAATCCCAAGCCCTGATGTCTTCCTGCCCAAAGTCCTGGACCTCATTGTCAATGGCATTTCTATCAACAGTGCTTATACCT
CCAAGATTCTGCCTCCAGAGAAGGAGGGAGGCCTGCCTCGGCAGGTGGGCAACAAGACCGAGTGTGCTCTGCTAGGCTTTGTCACAGATC
TGAAGCAGGATTATCAGGCTGTGCGTAATGAAGTGCCCGAGGAGAAGCTCTACAAGGTGTACACCTTTAACTCAGTGCGCAAGTCAATGA
GCACCGTCATCAGGAATCCCAACGGTGGCTTCCGTATGTACAGCAAGGGCGCCTCTGAGATCATCTTGCGCAAGTGTAATCGAATCCTGG
ACCGGAAAGGGGAAGCAGTGCCATTCAAGAATAAAGACAGAGATGATATGGTACGCACTGTCATCGAGCCCATGGCCTGTGATGGACTCC
GGACTATCTGCATAGCTTACCGGGACTTCGATGACACAGAGCCCTCTTGGGACAATGAGAATGAGATCCTCACCGAACTGACCTGTATCG
CGGTGGTGGGCATTGAGGACCCTGTGCGCCCAGAGGTGCCAGATGCTATTGCCAAATGCAAACAAGCTGGCATTACTGTCAGAATGGTGA
CAGGTGACAACATCAACACAGCCCGGGCCATTGCCACCAAATGTGGCATTCTGACACCTGGGGATGACTTCCTGTGCTTAGAAGGCAAAG
AATTCAACCGGCTCATCCGCAACGAGAAAGGCGAGGTAGAGCAAGAAAAGCTGGACAAGATCTGGCCTAAGCTTCGGGTCCTGGCGCGAT
CTTCTCCCACTGACAAGCACACCCTGGTGAAAGGCATAATTGACAGCACTGTTGGGGAACACCGGCAGGTCGTGGCTGTCACTGGTGATG
GCACAAATGACGGGCCTGCTCTGAAGAAAGCGGATGTTGGTTTTGCCATGGCAATGGAGAAGCTGCAGTTCCTTTACCTGTCAGACAACC
TGCTGGATTCTATCCCGGGGCCTTTGCCCCTGAGCCTGCGCTCTGTACACCTGCAGAATAACCTGATAGAGACCATGCAGAGAGACGTCT
TCTGTGACCCCGAGGAGCACAAACACACCCGCAGGCAGCTGGAAGACATCCGCCTGGATGGCAACCCCATCAACCTCAGCCTCTTCCCCA
GCGCCTACTTCTGCCTGCCTCGGCTCCCCATCGGCCGCTTCACGTAGCTCGGAGCCCTTCCACTCCTCCCAGGTCATCTCTTGGACCAGC
GGGCATCACATTCTCCAGCAGCCGCCATCTCACACGCCTCCCTCCTGTGGCCGCCGGCAGCATGGACAAAGGTCTCCATGCAGGGGGAGG
AGGCCTGCTTCTTTCCCCACAGCTCTCACGTCTCCCTTCTCCCTGCGGGTGACAAAGAAGCCCAAGGACCACCTCCTTCCTGCCTCATTG
TAATAAAATTCCCCACACTGA

>7872_7872_5_ATP2B4-OPTC_ATP2B4_chr1_203683405_ENST00000391954_OPTC_chr1_203472042_ENST00000367222_length(amino acids)=899AA_BP=811
MRGLVTAGKMTNPSDRVLPANSMAESREGDFGCTVMELRKLMELRSRDALTQINVHYGGVQNLCSRLKTSPVEGLSGNPADLEKRRQVFG
HNVIPPKKPKTFLELVWEALQDVTLIILEIAAIISLVLSFYRPAGEENELCGQVATTPEDENEAQAGWIEGAAILFSVIIVVLVTAFNDW
SKEKQFRGLQCRIEQEQKFSIIRNGQLIQLPVAEIVVGDIAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSLDKDPMLLSGTH
VMEGSGRMVVTAVGVNSQTGIILTLLGVNEDDEGEKKKKGKKQGVPENRNKAKTQDGVALEIQPLNSQEGIDNEEKDKKAVKVPKKEKSV
LQGKLTRLAVQIGKAGLLMSALTVFILILYFVIDNFVINRRPWLPECTPIYIQYFVKFFIIGITVLVVAVPEGLPLAVTISLAYSVKKMM
KDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQAYIGGIHYRQIPSPDVFLPKVLDLIVNGISINSAYTSKILPPEKEGGLPRQV
GNKTECALLGFVTDLKQDYQAVRNEVPEEKLYKVYTFNSVRKSMSTVIRNPNGGFRMYSKGASEIILRKCNRILDRKGEAVPFKNKDRDD
MVRTVIEPMACDGLRTICIAYRDFDDTEPSWDNENEILTELTCIAVVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCG
ILTPGDDFLCLEGKEFNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAVTGDGTNDGPALKKADVGFA
MAMEKLQFLYLSDNLLDSIPGPLPLSLRSVHLQNNLIETMQRDVFCDPEEHKHTRRQLEDIRLDGNPINLSLFPSAYFCLPRLPIGRFT

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ATP2B4-OPTC


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ATP2B4-OPTC


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ATP2B4-OPTC


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource