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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:CHMP1A-FANCA (FusionGDB2 ID:HG5119TG2175) |
Fusion Gene Summary for CHMP1A-FANCA |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: CHMP1A-FANCA | Fusion gene ID: hg5119tg2175 | Hgene | Tgene | Gene symbol | CHMP1A | FANCA | Gene ID | 5119 | 2175 |
| Gene name | charged multivesicular body protein 1A | FA complementation group A | |
| Synonyms | CHMP1|PCH8|PCOLN3|PRSM1|VPS46-1|VPS46A | FA|FA-H|FA1|FAA|FACA|FAH|FANCH | |
| Cytomap | ('CHMP1A')('FANCA') 16q24.3 | 16q24.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | charged multivesicular body protein 1acharged multivesicular body protein 1/chromatin modifying protein 1chromatin modifying protein 1Aprocollagen (type III) N-endopeptidaseprotease, metallo, 1, 33kDvacuolar protein sorting-associated protein 46-1 | Fanconi anemia group A proteinFanconi anemia complementation group AFanconi anemia, complementation group HFanconi anemia, type 1 | |
| Modification date | 20200313 | 20200313 | |
| UniProtAcc | . | . | |
| Ensembl transtripts involved in fusion gene | ENST00000253475, ENST00000397901, ENST00000550102, ENST00000535997, ENST00000547614, | ||
| Fusion gene scores | * DoF score | 6 X 9 X 5=270 | 9 X 13 X 6=702 |
| # samples | 9 | 15 | |
| ** MAII score | log2(9/270*10)=-1.58496250072116 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(15/702*10)=-2.22650852980868 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: CHMP1A [Title/Abstract] AND FANCA [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | CHMP1A(89723990)-FANCA(89851372), # samples:3 CHMP1A(89720312)-FANCA(89833645), # samples:3 | ||
| Anticipated loss of major functional domain due to fusion event. | CHMP1A-FANCA seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. CHMP1A-FANCA seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. CHMP1A-FANCA seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. CHMP1A-FANCA seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. CHMP1A-FANCA seems lost the major protein functional domain in Tgene partner, which is a CGC due to the frame-shifted ORF. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | CHMP1A | GO:0007076 | mitotic chromosome condensation | 11559747 |
| Hgene | CHMP1A | GO:0016192 | vesicle-mediated transport | 11559748 |
| Hgene | CHMP1A | GO:0016458 | gene silencing | 11559747 |
| Hgene | CHMP1A | GO:0045892 | negative regulation of transcription, DNA-templated | 11559747 |
| Fusion gene breakpoints across CHMP1A (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across FANCA (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | ESCA | TCGA-IG-A97H-01A | CHMP1A | chr16 | 89723990 | - | FANCA | chr16 | 89851372 | - |
| ChimerDB4 | ESCA | TCGA-IG-A97H | CHMP1A | chr16 | 89723989 | - | FANCA | chr16 | 89851372 | - |
| ChimerDB4 | ESCA | TCGA-IG-A97H | CHMP1A | chr16 | 89723990 | - | FANCA | chr16 | 89851372 | - |
| ChimerDB4 | STAD | TCGA-BR-8590-01A | CHMP1A | chr16 | 89720312 | - | FANCA | chr16 | 89833645 | - |
Top |
Fusion Gene ORF analysis for CHMP1A-FANCA |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-intron | ENST00000253475 | ENST00000389302 | CHMP1A | chr16 | 89723990 | - | FANCA | chr16 | 89851372 | - |
| 5CDS-intron | ENST00000253475 | ENST00000389302 | CHMP1A | chr16 | 89723989 | - | FANCA | chr16 | 89851372 | - |
| 5CDS-intron | ENST00000253475 | ENST00000534992 | CHMP1A | chr16 | 89723990 | - | FANCA | chr16 | 89851372 | - |
| 5CDS-intron | ENST00000253475 | ENST00000534992 | CHMP1A | chr16 | 89723989 | - | FANCA | chr16 | 89851372 | - |
| 5CDS-intron | ENST00000253475 | ENST00000543736 | CHMP1A | chr16 | 89723990 | - | FANCA | chr16 | 89851372 | - |
| 5CDS-intron | ENST00000253475 | ENST00000543736 | CHMP1A | chr16 | 89723989 | - | FANCA | chr16 | 89851372 | - |
| 5CDS-intron | ENST00000253475 | ENST00000563673 | CHMP1A | chr16 | 89723990 | - | FANCA | chr16 | 89851372 | - |
| 5CDS-intron | ENST00000253475 | ENST00000563673 | CHMP1A | chr16 | 89723989 | - | FANCA | chr16 | 89851372 | - |
| 5CDS-intron | ENST00000253475 | ENST00000567284 | CHMP1A | chr16 | 89723990 | - | FANCA | chr16 | 89851372 | - |
| 5CDS-intron | ENST00000253475 | ENST00000567284 | CHMP1A | chr16 | 89723989 | - | FANCA | chr16 | 89851372 | - |
| 5CDS-intron | ENST00000397901 | ENST00000389302 | CHMP1A | chr16 | 89723990 | - | FANCA | chr16 | 89851372 | - |
| 5CDS-intron | ENST00000397901 | ENST00000389302 | CHMP1A | chr16 | 89723989 | - | FANCA | chr16 | 89851372 | - |
| 5CDS-intron | ENST00000397901 | ENST00000389302 | CHMP1A | chr16 | 89720312 | - | FANCA | chr16 | 89833645 | - |
| 5CDS-intron | ENST00000397901 | ENST00000534992 | CHMP1A | chr16 | 89723990 | - | FANCA | chr16 | 89851372 | - |
| 5CDS-intron | ENST00000397901 | ENST00000534992 | CHMP1A | chr16 | 89723989 | - | FANCA | chr16 | 89851372 | - |
| 5CDS-intron | ENST00000397901 | ENST00000534992 | CHMP1A | chr16 | 89720312 | - | FANCA | chr16 | 89833645 | - |
| 5CDS-intron | ENST00000397901 | ENST00000543736 | CHMP1A | chr16 | 89723990 | - | FANCA | chr16 | 89851372 | - |
| 5CDS-intron | ENST00000397901 | ENST00000543736 | CHMP1A | chr16 | 89723989 | - | FANCA | chr16 | 89851372 | - |
| 5CDS-intron | ENST00000397901 | ENST00000543736 | CHMP1A | chr16 | 89720312 | - | FANCA | chr16 | 89833645 | - |
| 5CDS-intron | ENST00000397901 | ENST00000563673 | CHMP1A | chr16 | 89723990 | - | FANCA | chr16 | 89851372 | - |
| 5CDS-intron | ENST00000397901 | ENST00000563673 | CHMP1A | chr16 | 89723989 | - | FANCA | chr16 | 89851372 | - |
| 5CDS-intron | ENST00000397901 | ENST00000563673 | CHMP1A | chr16 | 89720312 | - | FANCA | chr16 | 89833645 | - |
| 5CDS-intron | ENST00000397901 | ENST00000567284 | CHMP1A | chr16 | 89723990 | - | FANCA | chr16 | 89851372 | - |
| 5CDS-intron | ENST00000397901 | ENST00000567284 | CHMP1A | chr16 | 89723989 | - | FANCA | chr16 | 89851372 | - |
| 5CDS-intron | ENST00000397901 | ENST00000567284 | CHMP1A | chr16 | 89720312 | - | FANCA | chr16 | 89833645 | - |
| 5CDS-intron | ENST00000550102 | ENST00000389302 | CHMP1A | chr16 | 89723990 | - | FANCA | chr16 | 89851372 | - |
| 5CDS-intron | ENST00000550102 | ENST00000389302 | CHMP1A | chr16 | 89723989 | - | FANCA | chr16 | 89851372 | - |
| 5CDS-intron | ENST00000550102 | ENST00000389302 | CHMP1A | chr16 | 89720312 | - | FANCA | chr16 | 89833645 | - |
| 5CDS-intron | ENST00000550102 | ENST00000534992 | CHMP1A | chr16 | 89723990 | - | FANCA | chr16 | 89851372 | - |
| 5CDS-intron | ENST00000550102 | ENST00000534992 | CHMP1A | chr16 | 89723989 | - | FANCA | chr16 | 89851372 | - |
| 5CDS-intron | ENST00000550102 | ENST00000534992 | CHMP1A | chr16 | 89720312 | - | FANCA | chr16 | 89833645 | - |
| 5CDS-intron | ENST00000550102 | ENST00000543736 | CHMP1A | chr16 | 89723990 | - | FANCA | chr16 | 89851372 | - |
| 5CDS-intron | ENST00000550102 | ENST00000543736 | CHMP1A | chr16 | 89723989 | - | FANCA | chr16 | 89851372 | - |
| 5CDS-intron | ENST00000550102 | ENST00000543736 | CHMP1A | chr16 | 89720312 | - | FANCA | chr16 | 89833645 | - |
| 5CDS-intron | ENST00000550102 | ENST00000563673 | CHMP1A | chr16 | 89723990 | - | FANCA | chr16 | 89851372 | - |
| 5CDS-intron | ENST00000550102 | ENST00000563673 | CHMP1A | chr16 | 89723989 | - | FANCA | chr16 | 89851372 | - |
| 5CDS-intron | ENST00000550102 | ENST00000563673 | CHMP1A | chr16 | 89720312 | - | FANCA | chr16 | 89833645 | - |
| 5CDS-intron | ENST00000550102 | ENST00000567284 | CHMP1A | chr16 | 89723990 | - | FANCA | chr16 | 89851372 | - |
| 5CDS-intron | ENST00000550102 | ENST00000567284 | CHMP1A | chr16 | 89723989 | - | FANCA | chr16 | 89851372 | - |
| 5CDS-intron | ENST00000550102 | ENST00000567284 | CHMP1A | chr16 | 89720312 | - | FANCA | chr16 | 89833645 | - |
| 5UTR-3CDS | ENST00000535997 | ENST00000389301 | CHMP1A | chr16 | 89723990 | - | FANCA | chr16 | 89851372 | - |
| 5UTR-3CDS | ENST00000535997 | ENST00000389301 | CHMP1A | chr16 | 89723989 | - | FANCA | chr16 | 89851372 | - |
| 5UTR-3CDS | ENST00000535997 | ENST00000568369 | CHMP1A | chr16 | 89723990 | - | FANCA | chr16 | 89851372 | - |
| 5UTR-3CDS | ENST00000535997 | ENST00000568369 | CHMP1A | chr16 | 89723989 | - | FANCA | chr16 | 89851372 | - |
| 5UTR-3CDS | ENST00000547614 | ENST00000389301 | CHMP1A | chr16 | 89723990 | - | FANCA | chr16 | 89851372 | - |
| 5UTR-3CDS | ENST00000547614 | ENST00000389301 | CHMP1A | chr16 | 89723989 | - | FANCA | chr16 | 89851372 | - |
| 5UTR-3CDS | ENST00000547614 | ENST00000568369 | CHMP1A | chr16 | 89723990 | - | FANCA | chr16 | 89851372 | - |
| 5UTR-3CDS | ENST00000547614 | ENST00000568369 | CHMP1A | chr16 | 89723989 | - | FANCA | chr16 | 89851372 | - |
| 5UTR-intron | ENST00000535997 | ENST00000389302 | CHMP1A | chr16 | 89723990 | - | FANCA | chr16 | 89851372 | - |
| 5UTR-intron | ENST00000535997 | ENST00000389302 | CHMP1A | chr16 | 89723989 | - | FANCA | chr16 | 89851372 | - |
| 5UTR-intron | ENST00000535997 | ENST00000534992 | CHMP1A | chr16 | 89723990 | - | FANCA | chr16 | 89851372 | - |
| 5UTR-intron | ENST00000535997 | ENST00000534992 | CHMP1A | chr16 | 89723989 | - | FANCA | chr16 | 89851372 | - |
| 5UTR-intron | ENST00000535997 | ENST00000543736 | CHMP1A | chr16 | 89723990 | - | FANCA | chr16 | 89851372 | - |
| 5UTR-intron | ENST00000535997 | ENST00000543736 | CHMP1A | chr16 | 89723989 | - | FANCA | chr16 | 89851372 | - |
| 5UTR-intron | ENST00000535997 | ENST00000563673 | CHMP1A | chr16 | 89723990 | - | FANCA | chr16 | 89851372 | - |
| 5UTR-intron | ENST00000535997 | ENST00000563673 | CHMP1A | chr16 | 89723989 | - | FANCA | chr16 | 89851372 | - |
| 5UTR-intron | ENST00000535997 | ENST00000567284 | CHMP1A | chr16 | 89723990 | - | FANCA | chr16 | 89851372 | - |
| 5UTR-intron | ENST00000535997 | ENST00000567284 | CHMP1A | chr16 | 89723989 | - | FANCA | chr16 | 89851372 | - |
| 5UTR-intron | ENST00000547614 | ENST00000389302 | CHMP1A | chr16 | 89723990 | - | FANCA | chr16 | 89851372 | - |
| 5UTR-intron | ENST00000547614 | ENST00000389302 | CHMP1A | chr16 | 89723989 | - | FANCA | chr16 | 89851372 | - |
| 5UTR-intron | ENST00000547614 | ENST00000534992 | CHMP1A | chr16 | 89723990 | - | FANCA | chr16 | 89851372 | - |
| 5UTR-intron | ENST00000547614 | ENST00000534992 | CHMP1A | chr16 | 89723989 | - | FANCA | chr16 | 89851372 | - |
| 5UTR-intron | ENST00000547614 | ENST00000543736 | CHMP1A | chr16 | 89723990 | - | FANCA | chr16 | 89851372 | - |
| 5UTR-intron | ENST00000547614 | ENST00000543736 | CHMP1A | chr16 | 89723989 | - | FANCA | chr16 | 89851372 | - |
| 5UTR-intron | ENST00000547614 | ENST00000563673 | CHMP1A | chr16 | 89723990 | - | FANCA | chr16 | 89851372 | - |
| 5UTR-intron | ENST00000547614 | ENST00000563673 | CHMP1A | chr16 | 89723989 | - | FANCA | chr16 | 89851372 | - |
| 5UTR-intron | ENST00000547614 | ENST00000567284 | CHMP1A | chr16 | 89723990 | - | FANCA | chr16 | 89851372 | - |
| 5UTR-intron | ENST00000547614 | ENST00000567284 | CHMP1A | chr16 | 89723989 | - | FANCA | chr16 | 89851372 | - |
| Frame-shift | ENST00000397901 | ENST00000389301 | CHMP1A | chr16 | 89720312 | - | FANCA | chr16 | 89833645 | - |
| Frame-shift | ENST00000397901 | ENST00000568369 | CHMP1A | chr16 | 89720312 | - | FANCA | chr16 | 89833645 | - |
| Frame-shift | ENST00000550102 | ENST00000389301 | CHMP1A | chr16 | 89720312 | - | FANCA | chr16 | 89833645 | - |
| Frame-shift | ENST00000550102 | ENST00000568369 | CHMP1A | chr16 | 89720312 | - | FANCA | chr16 | 89833645 | - |
| In-frame | ENST00000253475 | ENST00000389301 | CHMP1A | chr16 | 89723990 | - | FANCA | chr16 | 89851372 | - |
| In-frame | ENST00000253475 | ENST00000389301 | CHMP1A | chr16 | 89723989 | - | FANCA | chr16 | 89851372 | - |
| In-frame | ENST00000253475 | ENST00000568369 | CHMP1A | chr16 | 89723990 | - | FANCA | chr16 | 89851372 | - |
| In-frame | ENST00000253475 | ENST00000568369 | CHMP1A | chr16 | 89723989 | - | FANCA | chr16 | 89851372 | - |
| In-frame | ENST00000397901 | ENST00000389301 | CHMP1A | chr16 | 89723990 | - | FANCA | chr16 | 89851372 | - |
| In-frame | ENST00000397901 | ENST00000389301 | CHMP1A | chr16 | 89723989 | - | FANCA | chr16 | 89851372 | - |
| In-frame | ENST00000397901 | ENST00000568369 | CHMP1A | chr16 | 89723990 | - | FANCA | chr16 | 89851372 | - |
| In-frame | ENST00000397901 | ENST00000568369 | CHMP1A | chr16 | 89723989 | - | FANCA | chr16 | 89851372 | - |
| In-frame | ENST00000550102 | ENST00000389301 | CHMP1A | chr16 | 89723990 | - | FANCA | chr16 | 89851372 | - |
| In-frame | ENST00000550102 | ENST00000389301 | CHMP1A | chr16 | 89723989 | - | FANCA | chr16 | 89851372 | - |
| In-frame | ENST00000550102 | ENST00000568369 | CHMP1A | chr16 | 89723990 | - | FANCA | chr16 | 89851372 | - |
| In-frame | ENST00000550102 | ENST00000568369 | CHMP1A | chr16 | 89723989 | - | FANCA | chr16 | 89851372 | - |
| intron-3CDS | ENST00000253475 | ENST00000389301 | CHMP1A | chr16 | 89720312 | - | FANCA | chr16 | 89833645 | - |
| intron-3CDS | ENST00000253475 | ENST00000568369 | CHMP1A | chr16 | 89720312 | - | FANCA | chr16 | 89833645 | - |
| intron-3CDS | ENST00000535997 | ENST00000389301 | CHMP1A | chr16 | 89720312 | - | FANCA | chr16 | 89833645 | - |
| intron-3CDS | ENST00000535997 | ENST00000568369 | CHMP1A | chr16 | 89720312 | - | FANCA | chr16 | 89833645 | - |
| intron-3CDS | ENST00000547614 | ENST00000389301 | CHMP1A | chr16 | 89720312 | - | FANCA | chr16 | 89833645 | - |
| intron-3CDS | ENST00000547614 | ENST00000568369 | CHMP1A | chr16 | 89720312 | - | FANCA | chr16 | 89833645 | - |
| intron-intron | ENST00000253475 | ENST00000389302 | CHMP1A | chr16 | 89720312 | - | FANCA | chr16 | 89833645 | - |
| intron-intron | ENST00000253475 | ENST00000534992 | CHMP1A | chr16 | 89720312 | - | FANCA | chr16 | 89833645 | - |
| intron-intron | ENST00000253475 | ENST00000543736 | CHMP1A | chr16 | 89720312 | - | FANCA | chr16 | 89833645 | - |
| intron-intron | ENST00000253475 | ENST00000563673 | CHMP1A | chr16 | 89720312 | - | FANCA | chr16 | 89833645 | - |
| intron-intron | ENST00000253475 | ENST00000567284 | CHMP1A | chr16 | 89720312 | - | FANCA | chr16 | 89833645 | - |
| intron-intron | ENST00000535997 | ENST00000389302 | CHMP1A | chr16 | 89720312 | - | FANCA | chr16 | 89833645 | - |
| intron-intron | ENST00000535997 | ENST00000534992 | CHMP1A | chr16 | 89720312 | - | FANCA | chr16 | 89833645 | - |
| intron-intron | ENST00000535997 | ENST00000543736 | CHMP1A | chr16 | 89720312 | - | FANCA | chr16 | 89833645 | - |
| intron-intron | ENST00000535997 | ENST00000563673 | CHMP1A | chr16 | 89720312 | - | FANCA | chr16 | 89833645 | - |
| intron-intron | ENST00000535997 | ENST00000567284 | CHMP1A | chr16 | 89720312 | - | FANCA | chr16 | 89833645 | - |
| intron-intron | ENST00000547614 | ENST00000389302 | CHMP1A | chr16 | 89720312 | - | FANCA | chr16 | 89833645 | - |
| intron-intron | ENST00000547614 | ENST00000534992 | CHMP1A | chr16 | 89720312 | - | FANCA | chr16 | 89833645 | - |
| intron-intron | ENST00000547614 | ENST00000543736 | CHMP1A | chr16 | 89720312 | - | FANCA | chr16 | 89833645 | - |
| intron-intron | ENST00000547614 | ENST00000563673 | CHMP1A | chr16 | 89720312 | - | FANCA | chr16 | 89833645 | - |
| intron-intron | ENST00000547614 | ENST00000567284 | CHMP1A | chr16 | 89720312 | - | FANCA | chr16 | 89833645 | - |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000397901 | CHMP1A | chr16 | 89723990 | - | ENST00000389301 | FANCA | chr16 | 89851372 | - | 4325 | 264 | 210 | 3272 | 1020 |
| ENST00000397901 | CHMP1A | chr16 | 89723990 | - | ENST00000568369 | FANCA | chr16 | 89851372 | - | 3475 | 264 | 210 | 3179 | 989 |
| ENST00000253475 | CHMP1A | chr16 | 89723990 | - | ENST00000389301 | FANCA | chr16 | 89851372 | - | 4201 | 140 | 86 | 3148 | 1020 |
| ENST00000253475 | CHMP1A | chr16 | 89723990 | - | ENST00000568369 | FANCA | chr16 | 89851372 | - | 3351 | 140 | 86 | 3055 | 989 |
| ENST00000550102 | CHMP1A | chr16 | 89723990 | - | ENST00000389301 | FANCA | chr16 | 89851372 | - | 4130 | 69 | 15 | 3077 | 1020 |
| ENST00000550102 | CHMP1A | chr16 | 89723990 | - | ENST00000568369 | FANCA | chr16 | 89851372 | - | 3280 | 69 | 15 | 2984 | 989 |
| ENST00000397901 | CHMP1A | chr16 | 89723989 | - | ENST00000389301 | FANCA | chr16 | 89851372 | - | 4325 | 264 | 210 | 3272 | 1020 |
| ENST00000397901 | CHMP1A | chr16 | 89723989 | - | ENST00000568369 | FANCA | chr16 | 89851372 | - | 3475 | 264 | 210 | 3179 | 989 |
| ENST00000253475 | CHMP1A | chr16 | 89723989 | - | ENST00000389301 | FANCA | chr16 | 89851372 | - | 4201 | 140 | 86 | 3148 | 1020 |
| ENST00000253475 | CHMP1A | chr16 | 89723989 | - | ENST00000568369 | FANCA | chr16 | 89851372 | - | 3351 | 140 | 86 | 3055 | 989 |
| ENST00000550102 | CHMP1A | chr16 | 89723989 | - | ENST00000389301 | FANCA | chr16 | 89851372 | - | 4130 | 69 | 15 | 3077 | 1020 |
| ENST00000550102 | CHMP1A | chr16 | 89723989 | - | ENST00000568369 | FANCA | chr16 | 89851372 | - | 3280 | 69 | 15 | 2984 | 989 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000397901 | ENST00000389301 | CHMP1A | chr16 | 89723990 | - | FANCA | chr16 | 89851372 | - | 0.003159029 | 0.99684095 |
| ENST00000397901 | ENST00000568369 | CHMP1A | chr16 | 89723990 | - | FANCA | chr16 | 89851372 | - | 0.008013135 | 0.9919869 |
| ENST00000253475 | ENST00000389301 | CHMP1A | chr16 | 89723990 | - | FANCA | chr16 | 89851372 | - | 0.002935386 | 0.99706465 |
| ENST00000253475 | ENST00000568369 | CHMP1A | chr16 | 89723990 | - | FANCA | chr16 | 89851372 | - | 0.007597017 | 0.99240303 |
| ENST00000550102 | ENST00000389301 | CHMP1A | chr16 | 89723990 | - | FANCA | chr16 | 89851372 | - | 0.002900245 | 0.99709976 |
| ENST00000550102 | ENST00000568369 | CHMP1A | chr16 | 89723990 | - | FANCA | chr16 | 89851372 | - | 0.00762446 | 0.99237555 |
| ENST00000397901 | ENST00000389301 | CHMP1A | chr16 | 89723989 | - | FANCA | chr16 | 89851372 | - | 0.003159029 | 0.99684095 |
| ENST00000397901 | ENST00000568369 | CHMP1A | chr16 | 89723989 | - | FANCA | chr16 | 89851372 | - | 0.008013135 | 0.9919869 |
| ENST00000253475 | ENST00000389301 | CHMP1A | chr16 | 89723989 | - | FANCA | chr16 | 89851372 | - | 0.002935386 | 0.99706465 |
| ENST00000253475 | ENST00000568369 | CHMP1A | chr16 | 89723989 | - | FANCA | chr16 | 89851372 | - | 0.007597017 | 0.99240303 |
| ENST00000550102 | ENST00000389301 | CHMP1A | chr16 | 89723989 | - | FANCA | chr16 | 89851372 | - | 0.002900245 | 0.99709976 |
| ENST00000550102 | ENST00000568369 | CHMP1A | chr16 | 89723989 | - | FANCA | chr16 | 89851372 | - | 0.00762446 | 0.99237555 |
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Fusion Genomic Features for CHMP1A-FANCA |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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Fusion Protein Features for CHMP1A-FANCA |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr16:89723990/chr16:89851372) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | . |
| FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. | FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | FANCA | chr16:89723989 | chr16:89851372 | ENST00000389302 | 0 | 11 | 18_34 | 0 | 298.0 | Motif | Nuclear localization signal | |
| Tgene | FANCA | chr16:89723990 | chr16:89851372 | ENST00000389302 | 0 | 11 | 18_34 | 0 | 298.0 | Motif | Nuclear localization signal |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | CHMP1A | chr16:89723989 | chr16:89851372 | ENST00000397901 | - | 1 | 7 | 102_124 | 2 | 197.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | CHMP1A | chr16:89723989 | chr16:89851372 | ENST00000397901 | - | 1 | 7 | 5_47 | 2 | 197.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | CHMP1A | chr16:89723990 | chr16:89851372 | ENST00000397901 | - | 1 | 7 | 102_124 | 2 | 197.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | CHMP1A | chr16:89723990 | chr16:89851372 | ENST00000397901 | - | 1 | 7 | 5_47 | 2 | 197.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | CHMP1A | chr16:89723989 | chr16:89851372 | ENST00000397901 | - | 1 | 7 | 185_195 | 2 | 197.0 | Motif | Note=MIT-interacting motif |
| Hgene | CHMP1A | chr16:89723990 | chr16:89851372 | ENST00000397901 | - | 1 | 7 | 185_195 | 2 | 197.0 | Motif | Note=MIT-interacting motif |
| Tgene | FANCA | chr16:89723989 | chr16:89851372 | ENST00000389301 | 13 | 43 | 18_34 | 453 | 1456.0 | Motif | Nuclear localization signal | |
| Tgene | FANCA | chr16:89723990 | chr16:89851372 | ENST00000389301 | 13 | 43 | 18_34 | 453 | 1456.0 | Motif | Nuclear localization signal |
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Fusion Gene Sequence for CHMP1A-FANCA |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >16524_16524_1_CHMP1A-FANCA_CHMP1A_chr16_89723989_ENST00000253475_FANCA_chr16_89851372_ENST00000389301_length(transcript)=4201nt_BP=140nt CCGGAAGTGGGGCGGCGACCCCGGAAGTCCCCGCCGGGTGCAGCTTGGTCGGTTCGATCGCCGCCGGGACCTGACACCGCCCGGAGTTGG CGTCCCTTCTCCCTCTCCGAGTGCTGCTCCTGTCATTGTGGCCATGGACGGCCTCCTTTGGGAGCACACGAGGCTACCATGGCTGCAGCA AGAAGGCCCTGGTCTTCCTGTTTACGTTCTTGTCAGAACTCGTGCCTTTTGAGTCTCCCCGGTACCTGCAGGTGCACATTCTCCACCCAC CCCTGGTTCCCGGCAAGTACCGCTCCCTCCTCACAGACTACATCTCATTGGCCAAGACACGGCTGGCCGACCTCAAGGTTTCTATAGAAA ACATGGGACTCTACGAGGATTTGTCATCAGCTGGGGACATTACTGAGCCCCACAGCCAAGCTCTTCAGGATGTTGAAAAGGCCATCATGG TGTTTGAGCATACGGGGAACATCCCAGTCACCGTCATGGAGGCCAGCATATTCAGGAGGCCTTACTACGTGTCCCACTTCCTCCCCGCCC TGCTCACACCTCGAGTGCTCCCCAAAGTCCCTGACTCCCGTGTGGCGTTTATAGAGTCTCTGAAGAGAGCAGATAAAATCCCCCCATCTC TGTACTCCACCTACTGCCAGGCCTGCTCTGCTGCTGAAGAGAAGCCAGAAGATGCAGCCCTGGGAGTGAGGGCAGAACCCAACTCTGCTG AGGAGCCCCTGGGACAGCTCACAGCTGCACTGGGAGAGCTGAGAGCCTCCATGACAGACCCCAGCCAGCGTGATGTTATATCGGCACAGG TGGCAGTGATTTCTGAAAGACTGAGGGCTGTCCTGGGCCACAATGAGGATGACAGCAGCGTTGAGATATCAAAGATTCAGCTCAGCATCA ACACGCCGAGACTGGAGCCACGGGAACACATGGCTGTGGACCTCCTGCTGACGTCTTTCTGTCAGAACCTGATGGCTGCCTCCAGTGTCG CTCCCCCGGAGAGGCAGGGTCCCTGGGCTGCCCTCTTCGTGAGGACCATGTGTGGACGTGTGCTCCCTGCAGTGCTCACCCGGCTCTGCC AGCTGCTCCGTCACCAGGGCCCGAGCCTGAGTGCCCCACATGTGCTGGGGTTGGCTGCCCTGGCCGTGCACCTGGGTGAGTCCAGGTCTG CGCTCCCAGAGGTGGATGTGGGTCCTCCTGCACCTGGTGCTGGCCTTCCTGTCCCTGCGCTCTTTGACAGCCTCCTGACCTGTAGGACGA GGGATTCCTTGTTCTTCTGCCTGAAATTTTGTACAGCAGCAATTTCTTACTCTCTCTGCAAGTTTTCTTCCCAGTCACGAGATACTTTGT GCAGCTGCTTATCTCCAGGCCTTATTAAAAAGTTTCAGTTCCTCATGTTCAGATTGTTCTCAGAGGCCCGACAGCCTCTTTCTGAGGAGG ACGTAGCCAGCCTTTCCTGGAGACCCTTGCACCTTCCTTCTGCAGACTGGCAGAGAGCTGCCCTCTCTCTCTGGACACACAGAACCTTCC GAGAGGTGTTGAAAGAGGAAGATGTTCACTTAACTTACCAAGACTGGTTACACCTGGAGCTGGAAATTCAACCTGAAGCTGATGCTCTTT CAGATACTGAACGGCAGGACTTCCACCAGTGGGCGATCCATGAGCACTTTCTCCCTGAGTCCTCGGCTTCAGGGGGCTGTGACGGAGACC TGCAGGCTGCGTGTACCATTCTTGTCAACGCACTGATGGATTTCCACCAAAGCTCAAGGAGTTATGACCACTCAGAAAATTCTGATTTGG TCTTTGGTGGCCGCACAGGAAATGAGGATATTATTTCCAGATTGCAGGAGATGGTAGCTGACCTGGAGCTGCAGCAAGACCTCATAGTGC CTCTCGGCCACACCCCTTCCCAGGAGCACTTCCTCTTTGAGATTTTCCGCAGACGGCTCCAGGCTCTGACAAGCGGGTGGAGCGTGGCTG CCAGCCTTCAGAGACAGAGGGAGCTGCTAATGTACAAACGGATCCTCCTCCGCCTGCCTTCGTCTGTCCTCTGCGGCAGCAGCTTCCAGG CAGAACAGCCCATCACTGCCAGATGCGAGCAGTTCTTCCACTTGGTCAACTCTGAGATGAGAAACTTCTGCTCCCACGGAGGTGCCCTGA CACAGGACATCACTGCCCACTTCTTCAGGGGCCTCCTGAACGCCTGTCTGCGGAGCAGAGACCCCTCCCTGATGGTCGACTTCATACTGG CCAAGTGCCAGACGAAATGCCCCTTAATTTTGACCTCTGCTCTGGTGTGGTGGCCGAGCCTGGAGCCTGTGCTGCTCTGCCGGTGGAGGA GACACTGCCAGAGCCCGCTGCCCCGGGAACTGCAGAAGCTACAAGAAGGCCGGCAGTTTGCCAGCGATTTCCTCTCCCCTGAGGCTGCCT CCCCAGCACCCAACCCGGACTGGCTCTCAGCTGCTGCACTGCACTTTGCGATTCAACAAGTCAGGGAAGAAAACATCAGGAAGCAGCTAA AGAAGCTGGACTGCGAGAGAGAGGAGCTATTGGTTTTCCTTTTCTTCTTCTCCTTGATGGGCCTGCTGTCGTCACATCTGACCTCAAATA GCACCACAGACCTGCCAAAGGCTTTCCACGTTTGTGCAGCAATCCTCGAGTGTTTAGAGAAGAGGAAGATATCCTGGCTGGCACTCTTTC AGTTGACAGAGAGTGACCTCAGGCTGGGGCGGCTCCTCCTCCGTGTGGCCCCGGATCAGCACACCAGGCTGCTGCCTTTCGCTTTTTACA GTCTTCTCTCCTACTTCCATGAAGACGCGGCCATCAGGGAAGAGGCCTTCCTGCATGTTGCTGTGGACATGTACTTGAAGCTGGTCCAGC TCTTCGTGGCTGGGGATACAAGCACAGTTTCACCTCCAGCTGGCAGGAGCCTGGAGCTCAAGGGTCAGGGCAACCCCGTGGAACTGATAA CAAAAGCTCGTCTTTTTCTGCTGCAGTTAATACCTCGGTGCCCGAAAAAGAGCTTCTCACACGTGGCAGAGCTGCTGGCTGATCGTGGGG ACTGCGACCCAGAGGTGAGCGCCGCCCTCCAGAGCAGACAGCAGGCTGCCCCTGACGCTGACCTGTCCCAGGAGCCTCATCTCTTCTGAC GGGACCTGCCACTGCACACCAGCCCAGCTCCCGTGTAAATAATTTATTACAAGCATAACATGGAGCTCTTGTTGCACTAAAAAGTGGATT ACAAATCTCCTCGACTGCTTTAGTGGGGAAAGGAATCAATTATTTATGAACTGTCCGGCCCCGAGTCACTCAGCGTTTGCGGGAAAATAA ACCACTGGTCCCAGAGCAGAGGAAGGCTACTTGAGCCGGACACCAAGCCCGCCTCCAGCACCAAGGGCGGGCAGCACCCTCCGACCCTCC CATGCGGGTGCACACGAAGGGTGAGGCTGACACAGCCACTGCGGAGTCCAGGCTGCTAGAGGTGCTCATCCTCACTGCCGTCCTCAGGTG GGTTCGGGCTTCACCGCCTGGCCCTCTGTGGTCACAGAGGGGCTCGGTGGCCCAGGTGGTGGTTCCGCCTCCAGGGGCAGGGCCTTGTCC TGGGTCTGTGTCAGCGGGTGCACCATGGACATGTGTACATTGAGGTTGTGGGCCTTCTCAAACCGCCGGCCACACTGGTCACAGGCAAAG TCCAGCTCAGTCTCAGCCTTGTGTTTGGTCATGTGGTACTTGAGGGATGCCCGCTGCCTGCACTGGAACCCACAGACCTCACACCTGGGG GACAGAGGCAGATAAGAAGGTGCGAGGGCCACAGCCCTGGGAGGGGGTCCTGACTCACACTTACTGCAAAGGCTTGGCTCCCGAATGTCG CATTTGGTGGACGAGAAGGTGCTTCCGCTGCTTGAAGGTTTGTCCACATTCGTCACAGATATAGTTCCGCACCTCTGAGAGGGGAGAGTC CAGTGAGTCCAGGCCCCTGATGCTCCAACCTCCCGGGGGGACGACGATGACAATGTGAAACCATCACAGCTGGGAAGACATTTCTGCACA TGGTTCACCATGCAGTGGGCCCAAGCAAGGGGCCTATGAGGGCCTCGTTTATTAAGATCTTTAAACTGCTTTATACACTGTCACGTGGCT >16524_16524_1_CHMP1A-FANCA_CHMP1A_chr16_89723989_ENST00000253475_FANCA_chr16_89851372_ENST00000389301_length(amino acids)=1020AA_BP=18 MASLLPLRVLLLSLWPWTASFGSTRGYHGCSKKALVFLFTFLSELVPFESPRYLQVHILHPPLVPGKYRSLLTDYISLAKTRLADLKVSI ENMGLYEDLSSAGDITEPHSQALQDVEKAIMVFEHTGNIPVTVMEASIFRRPYYVSHFLPALLTPRVLPKVPDSRVAFIESLKRADKIPP SLYSTYCQACSAAEEKPEDAALGVRAEPNSAEEPLGQLTAALGELRASMTDPSQRDVISAQVAVISERLRAVLGHNEDDSSVEISKIQLS INTPRLEPREHMAVDLLLTSFCQNLMAASSVAPPERQGPWAALFVRTMCGRVLPAVLTRLCQLLRHQGPSLSAPHVLGLAALAVHLGESR SALPEVDVGPPAPGAGLPVPALFDSLLTCRTRDSLFFCLKFCTAAISYSLCKFSSQSRDTLCSCLSPGLIKKFQFLMFRLFSEARQPLSE EDVASLSWRPLHLPSADWQRAALSLWTHRTFREVLKEEDVHLTYQDWLHLELEIQPEADALSDTERQDFHQWAIHEHFLPESSASGGCDG DLQAACTILVNALMDFHQSSRSYDHSENSDLVFGGRTGNEDIISRLQEMVADLELQQDLIVPLGHTPSQEHFLFEIFRRRLQALTSGWSV AASLQRQRELLMYKRILLRLPSSVLCGSSFQAEQPITARCEQFFHLVNSEMRNFCSHGGALTQDITAHFFRGLLNACLRSRDPSLMVDFI LAKCQTKCPLILTSALVWWPSLEPVLLCRWRRHCQSPLPRELQKLQEGRQFASDFLSPEAASPAPNPDWLSAAALHFAIQQVREENIRKQ LKKLDCEREELLVFLFFFSLMGLLSSHLTSNSTTDLPKAFHVCAAILECLEKRKISWLALFQLTESDLRLGRLLLRVAPDQHTRLLPFAF YSLLSYFHEDAAIREEAFLHVAVDMYLKLVQLFVAGDTSTVSPPAGRSLELKGQGNPVELITKARLFLLQLIPRCPKKSFSHVAELLADR -------------------------------------------------------------- >16524_16524_2_CHMP1A-FANCA_CHMP1A_chr16_89723989_ENST00000253475_FANCA_chr16_89851372_ENST00000568369_length(transcript)=3351nt_BP=140nt CCGGAAGTGGGGCGGCGACCCCGGAAGTCCCCGCCGGGTGCAGCTTGGTCGGTTCGATCGCCGCCGGGACCTGACACCGCCCGGAGTTGG CGTCCCTTCTCCCTCTCCGAGTGCTGCTCCTGTCATTGTGGCCATGGACGGCCTCCTTTGGGAGCACACGAGGCTACCATGGCTGCAGCA AGAAGGCCCTGGTCTTCCTGTTTACGTTCTTGTCAGAACTCGTGCCTTTTGAGTCTCCCCGGTACCTGCAGGTGCACATTCTCCACCCAC CCCTGGTTCCCGGCAAGTACCGCTCCCTCCTCACAGACTACATCTCATTGGCCAAGACACGGCTGGCCGACCTCAAGGTTTCTATAGAAA ACATGGGACTCTACGAGGATTTGTCATCAGCTGGGGACATTACTGAGCCCCACAGCCAAGCTCTTCAGGATGTTGAAAAGGCCATCATGG TGTTTGAGCATACGGGGAACATCCCAGTCACCGTCATGGAGGCCAGCATATTCAGGAGGCCTTACTACGTGTCCCACTTCCTCCCCGCCC TGCTCACACCTCGAGTGCTCCCCAAAGTCCCTGACTCCCGTGTGGCGTTTATAGAGTCTCTGAAGAGAGCAGATAAAATCCCCCCATCTC TGTACTCCACCTACTGCCAGGCCTGCTCTGCTGCTGAAGAGAAGCCAGAAGATGCAGCCCTGGGAGTGAGGGCAGAACCCAACTCTGCTG AGGAGCCCCTGGGACAGCTCACAGCTGCACTGGGAGAGCTGAGAGCCTCCATGACAGACCCCAGCCAGCGTGATGTTATATCGGCACAGG TGGCAGTGATTTCTGAAAGACTGAGGGCTGTCCTGGGCCACAATGAGGATGACAGCAGCGTTGAGATATCAAAGATTCAGCTCAGCATCA ACACGCCGAGACTGGAGCCACGGGAACACATGGCTGTGGACCTCCTGCTGACGTCTTTCTGTCAGAACCTGATGGCTGCCTCCAGTGTCG CTCCCCCGGAGAGGCAGGGTCCCTGGGCTGCCCTCTTCGTGAGGACCATGTGTGGACGTGTGCTCCCTGCAGTGCTCACCCGGCTCTGCC AGCTGCTCCGTCACCAGGGCCCGAGCCTGAGTGCCCCACATGTGCTGGGGTTGGCTGCCCTGGCCGTGCACCTGGGTGAGTCCAGGTCTG CGCTCCCAGAGGTGGATGTGGGTCCTCCTGCACCTGGTGCTGGCCTTCCTGTCCCTGCGCTCTTTGACAGCCTCCTGACCTGTAGGACGA GGGATTCCTTGTTCTTCTGCCTGAAATTTTGTACAGCAGCAATTTCTTACTCTCTCTGCAAGTTTTCTTCCCAGTCACGAGATACTTTGT GCAGCTGCTTATCTCCAGGCCTTATTAAAAAGTTTCAGTTCCTCATGTTCAGATTGTTCTCAGAGGCCCGACAGCCTCTTTCTGAGGAGG ACGTAGCCAGCCTTTCCTGGAGACCCTTGCACCTTCCTTCTGCAGACTGGCAGAGAGCTGCCCTCTCTCTCTGGACACACAGAACCTTCC GAGAGGTGTTGAAAGAGGAAGATGTTCACTTAACTTACCAAGACTGGTTACACCTGGAGCTGGAAATTCAACCTGAAGCTGATGCTCTTT CAGATACTGAACGGCAGGACTTCCACCAGTGGGCGATCCATGAGCACTTTCTCCCTGAGTCCTCGGCTTCAGGGGGCTGTGACGGAGACC TGCAGGCTGCGTGTACCATTCTTGTCAACGCACTGATGGATTTCCACCAAAGCTCAAGGAGTTATGACCACTCAGAAAATTCTGATTTGG TCTTTGGTGGCCGCACAGGAAATGAGGATATTATTTCCAGATTGCAGGAGATGGTAGCTGACCTGGAGCTGCAGCAAGACCTCATAGTGC CTCTCGGCCACACCCCTTCCCAGGAGCACTTCCTCTTTGAGATTTTCCGCAGACGGCTCCAGGCTCTGACAAGCGGGTGGAGCGTGGCTG CCAGCCTTCAGAGACAGAGGGAGCTGCTAATGTACAAACGGATCCTCCTCCGCCTGCCTTCGTCTGTCCTCTGCGGCAGCAGCTTCCAGG CAGAACAGCCCATCACTGCCAGATGCGAGCAGTTCTTCCACTTGGTCAACTCTGAGATGAGAAACTTCTGCTCCCACGGAGGTGCCCTGA CACAGGACATCACTGCCCACTTCTTCAGGGGCCTCCTGAACGCCTGTCTGCGGAGCAGAGACCCCTCCCTGATGGTCGACTTCATACTGG CCAAGTGCCAGACGAAATGCCCCTTAATTTTGACCTCTGCTCTGGTGTGGTGGCCGAGCCTGGAGCCTGTGCTGCTCTGCCGGTGGAGGA GACACTGCCAGAGCCCGCTGCCCCGGGAACTGCAGAAGCTACAAGAAGGCCGGCAGTTTGCCAGCGATTTCCTCTCCCCTGAGGCTGCCT CCCCAGCACCCAACCCGGACTGGCTCTCAGCTGCTGCACTGCACTTTGCGATTCAACAAGTCAGGGAAGAAAACATCAGGAAGCAGCTAA AGAAGCTGGACTGCGAGAGAGAGGAGCTATTGGTTTTCCTTTTCTTCTTCTCCTTGATGGGCCTGCTGTCGTCACATCTGACCTCAAATA GCACCACAGACCTGCCAAAGGCTTTCCACGTTTGTGCAGCAATCCTCGAGTGTTTAGAGAAGAGGAAGATATCCTGGCTGGCACTCTTTC AGTTGACAGAGAGTGACCTCAGGCTGGGGCGGCTCCTCCTCCGTGTGGCCCCGGATCAGCACACCAGGCTGCTGCCTTTCGCTTTTTACA GTCTTCTCTCCTACTTCCATGAAGACGCGGCCATCAGGGAAGAGGCCTTCCTGCATGTTGCTGTGGACATGTACTTGAAGCTGGTCCAGC TCTTCGTGGCTGGGGATACAAGCACAGTTTCACCTCCAGCTGGCAGGAGCCTGGAGCTCAAGGGTCAGGCAGGGCAACCCCGTGGAACTG ATAACAAAAGCTCGTCTTTTTCTGCTGCAGTTAATACCTCGGTGCCCGAAAAAGAGCTTCTCACACGTGGCAGAGCTGCTGGCTGATCGT GGGGACTGCGACCCAGAGGTGAGCGCCGCCCTCCAGAGCAGACAGCAGGCTGCCCCTGACGCTGACCTGTCCCAGGAGCCTCATCTCTTC TGACGGGACCTGCCACTGCACACCAGCCCAGCTCCCGTGTAAATAATTTATTACAAGCATAACATGGAGCTCTTGTTGCACTAAAAAGTG GATTACAAATCTCCTCGACTGCTTTAGTGGGGAAAGGAATCAATTATTTATGAACTGTCCGGCCCCGAGTCACTCAGCGTTTGCGGGAAA >16524_16524_2_CHMP1A-FANCA_CHMP1A_chr16_89723989_ENST00000253475_FANCA_chr16_89851372_ENST00000568369_length(amino acids)=989AA_BP=18 MASLLPLRVLLLSLWPWTASFGSTRGYHGCSKKALVFLFTFLSELVPFESPRYLQVHILHPPLVPGKYRSLLTDYISLAKTRLADLKVSI ENMGLYEDLSSAGDITEPHSQALQDVEKAIMVFEHTGNIPVTVMEASIFRRPYYVSHFLPALLTPRVLPKVPDSRVAFIESLKRADKIPP SLYSTYCQACSAAEEKPEDAALGVRAEPNSAEEPLGQLTAALGELRASMTDPSQRDVISAQVAVISERLRAVLGHNEDDSSVEISKIQLS INTPRLEPREHMAVDLLLTSFCQNLMAASSVAPPERQGPWAALFVRTMCGRVLPAVLTRLCQLLRHQGPSLSAPHVLGLAALAVHLGESR SALPEVDVGPPAPGAGLPVPALFDSLLTCRTRDSLFFCLKFCTAAISYSLCKFSSQSRDTLCSCLSPGLIKKFQFLMFRLFSEARQPLSE EDVASLSWRPLHLPSADWQRAALSLWTHRTFREVLKEEDVHLTYQDWLHLELEIQPEADALSDTERQDFHQWAIHEHFLPESSASGGCDG DLQAACTILVNALMDFHQSSRSYDHSENSDLVFGGRTGNEDIISRLQEMVADLELQQDLIVPLGHTPSQEHFLFEIFRRRLQALTSGWSV AASLQRQRELLMYKRILLRLPSSVLCGSSFQAEQPITARCEQFFHLVNSEMRNFCSHGGALTQDITAHFFRGLLNACLRSRDPSLMVDFI LAKCQTKCPLILTSALVWWPSLEPVLLCRWRRHCQSPLPRELQKLQEGRQFASDFLSPEAASPAPNPDWLSAAALHFAIQQVREENIRKQ LKKLDCEREELLVFLFFFSLMGLLSSHLTSNSTTDLPKAFHVCAAILECLEKRKISWLALFQLTESDLRLGRLLLRVAPDQHTRLLPFAF -------------------------------------------------------------- >16524_16524_3_CHMP1A-FANCA_CHMP1A_chr16_89723989_ENST00000397901_FANCA_chr16_89851372_ENST00000389301_length(transcript)=4325nt_BP=264nt AGCGACTCACAAAAGGTCCTCGCGCCAGCGGCGTGCGTCACCATGGCGACCGCGCGCCGCGCAGCCGCGCCCCGCCCCTCTGGCGGGACC GGCCACCATCCTCTCGCGAGAGCATCCCGTGCGACCGGAAGTGGGGCGGCGACCCCGGAAGTCCCCGCCGGGTGCAGCTTGGTCGGTTCG ATCGCCGCCGGGACCTGACACCGCCCGGAGTTGGCGTCCCTTCTCCCTCTCCGAGTGCTGCTCCTGTCATTGTGGCCATGGACGGCCTCC TTTGGGAGCACACGAGGCTACCATGGCTGCAGCAAGAAGGCCCTGGTCTTCCTGTTTACGTTCTTGTCAGAACTCGTGCCTTTTGAGTCT CCCCGGTACCTGCAGGTGCACATTCTCCACCCACCCCTGGTTCCCGGCAAGTACCGCTCCCTCCTCACAGACTACATCTCATTGGCCAAG ACACGGCTGGCCGACCTCAAGGTTTCTATAGAAAACATGGGACTCTACGAGGATTTGTCATCAGCTGGGGACATTACTGAGCCCCACAGC CAAGCTCTTCAGGATGTTGAAAAGGCCATCATGGTGTTTGAGCATACGGGGAACATCCCAGTCACCGTCATGGAGGCCAGCATATTCAGG AGGCCTTACTACGTGTCCCACTTCCTCCCCGCCCTGCTCACACCTCGAGTGCTCCCCAAAGTCCCTGACTCCCGTGTGGCGTTTATAGAG TCTCTGAAGAGAGCAGATAAAATCCCCCCATCTCTGTACTCCACCTACTGCCAGGCCTGCTCTGCTGCTGAAGAGAAGCCAGAAGATGCA GCCCTGGGAGTGAGGGCAGAACCCAACTCTGCTGAGGAGCCCCTGGGACAGCTCACAGCTGCACTGGGAGAGCTGAGAGCCTCCATGACA GACCCCAGCCAGCGTGATGTTATATCGGCACAGGTGGCAGTGATTTCTGAAAGACTGAGGGCTGTCCTGGGCCACAATGAGGATGACAGC AGCGTTGAGATATCAAAGATTCAGCTCAGCATCAACACGCCGAGACTGGAGCCACGGGAACACATGGCTGTGGACCTCCTGCTGACGTCT TTCTGTCAGAACCTGATGGCTGCCTCCAGTGTCGCTCCCCCGGAGAGGCAGGGTCCCTGGGCTGCCCTCTTCGTGAGGACCATGTGTGGA CGTGTGCTCCCTGCAGTGCTCACCCGGCTCTGCCAGCTGCTCCGTCACCAGGGCCCGAGCCTGAGTGCCCCACATGTGCTGGGGTTGGCT GCCCTGGCCGTGCACCTGGGTGAGTCCAGGTCTGCGCTCCCAGAGGTGGATGTGGGTCCTCCTGCACCTGGTGCTGGCCTTCCTGTCCCT GCGCTCTTTGACAGCCTCCTGACCTGTAGGACGAGGGATTCCTTGTTCTTCTGCCTGAAATTTTGTACAGCAGCAATTTCTTACTCTCTC TGCAAGTTTTCTTCCCAGTCACGAGATACTTTGTGCAGCTGCTTATCTCCAGGCCTTATTAAAAAGTTTCAGTTCCTCATGTTCAGATTG TTCTCAGAGGCCCGACAGCCTCTTTCTGAGGAGGACGTAGCCAGCCTTTCCTGGAGACCCTTGCACCTTCCTTCTGCAGACTGGCAGAGA GCTGCCCTCTCTCTCTGGACACACAGAACCTTCCGAGAGGTGTTGAAAGAGGAAGATGTTCACTTAACTTACCAAGACTGGTTACACCTG GAGCTGGAAATTCAACCTGAAGCTGATGCTCTTTCAGATACTGAACGGCAGGACTTCCACCAGTGGGCGATCCATGAGCACTTTCTCCCT GAGTCCTCGGCTTCAGGGGGCTGTGACGGAGACCTGCAGGCTGCGTGTACCATTCTTGTCAACGCACTGATGGATTTCCACCAAAGCTCA AGGAGTTATGACCACTCAGAAAATTCTGATTTGGTCTTTGGTGGCCGCACAGGAAATGAGGATATTATTTCCAGATTGCAGGAGATGGTA GCTGACCTGGAGCTGCAGCAAGACCTCATAGTGCCTCTCGGCCACACCCCTTCCCAGGAGCACTTCCTCTTTGAGATTTTCCGCAGACGG CTCCAGGCTCTGACAAGCGGGTGGAGCGTGGCTGCCAGCCTTCAGAGACAGAGGGAGCTGCTAATGTACAAACGGATCCTCCTCCGCCTG CCTTCGTCTGTCCTCTGCGGCAGCAGCTTCCAGGCAGAACAGCCCATCACTGCCAGATGCGAGCAGTTCTTCCACTTGGTCAACTCTGAG ATGAGAAACTTCTGCTCCCACGGAGGTGCCCTGACACAGGACATCACTGCCCACTTCTTCAGGGGCCTCCTGAACGCCTGTCTGCGGAGC AGAGACCCCTCCCTGATGGTCGACTTCATACTGGCCAAGTGCCAGACGAAATGCCCCTTAATTTTGACCTCTGCTCTGGTGTGGTGGCCG AGCCTGGAGCCTGTGCTGCTCTGCCGGTGGAGGAGACACTGCCAGAGCCCGCTGCCCCGGGAACTGCAGAAGCTACAAGAAGGCCGGCAG TTTGCCAGCGATTTCCTCTCCCCTGAGGCTGCCTCCCCAGCACCCAACCCGGACTGGCTCTCAGCTGCTGCACTGCACTTTGCGATTCAA CAAGTCAGGGAAGAAAACATCAGGAAGCAGCTAAAGAAGCTGGACTGCGAGAGAGAGGAGCTATTGGTTTTCCTTTTCTTCTTCTCCTTG ATGGGCCTGCTGTCGTCACATCTGACCTCAAATAGCACCACAGACCTGCCAAAGGCTTTCCACGTTTGTGCAGCAATCCTCGAGTGTTTA GAGAAGAGGAAGATATCCTGGCTGGCACTCTTTCAGTTGACAGAGAGTGACCTCAGGCTGGGGCGGCTCCTCCTCCGTGTGGCCCCGGAT CAGCACACCAGGCTGCTGCCTTTCGCTTTTTACAGTCTTCTCTCCTACTTCCATGAAGACGCGGCCATCAGGGAAGAGGCCTTCCTGCAT GTTGCTGTGGACATGTACTTGAAGCTGGTCCAGCTCTTCGTGGCTGGGGATACAAGCACAGTTTCACCTCCAGCTGGCAGGAGCCTGGAG CTCAAGGGTCAGGGCAACCCCGTGGAACTGATAACAAAAGCTCGTCTTTTTCTGCTGCAGTTAATACCTCGGTGCCCGAAAAAGAGCTTC TCACACGTGGCAGAGCTGCTGGCTGATCGTGGGGACTGCGACCCAGAGGTGAGCGCCGCCCTCCAGAGCAGACAGCAGGCTGCCCCTGAC GCTGACCTGTCCCAGGAGCCTCATCTCTTCTGACGGGACCTGCCACTGCACACCAGCCCAGCTCCCGTGTAAATAATTTATTACAAGCAT AACATGGAGCTCTTGTTGCACTAAAAAGTGGATTACAAATCTCCTCGACTGCTTTAGTGGGGAAAGGAATCAATTATTTATGAACTGTCC GGCCCCGAGTCACTCAGCGTTTGCGGGAAAATAAACCACTGGTCCCAGAGCAGAGGAAGGCTACTTGAGCCGGACACCAAGCCCGCCTCC AGCACCAAGGGCGGGCAGCACCCTCCGACCCTCCCATGCGGGTGCACACGAAGGGTGAGGCTGACACAGCCACTGCGGAGTCCAGGCTGC TAGAGGTGCTCATCCTCACTGCCGTCCTCAGGTGGGTTCGGGCTTCACCGCCTGGCCCTCTGTGGTCACAGAGGGGCTCGGTGGCCCAGG TGGTGGTTCCGCCTCCAGGGGCAGGGCCTTGTCCTGGGTCTGTGTCAGCGGGTGCACCATGGACATGTGTACATTGAGGTTGTGGGCCTT CTCAAACCGCCGGCCACACTGGTCACAGGCAAAGTCCAGCTCAGTCTCAGCCTTGTGTTTGGTCATGTGGTACTTGAGGGATGCCCGCTG CCTGCACTGGAACCCACAGACCTCACACCTGGGGGACAGAGGCAGATAAGAAGGTGCGAGGGCCACAGCCCTGGGAGGGGGTCCTGACTC ACACTTACTGCAAAGGCTTGGCTCCCGAATGTCGCATTTGGTGGACGAGAAGGTGCTTCCGCTGCTTGAAGGTTTGTCCACATTCGTCAC AGATATAGTTCCGCACCTCTGAGAGGGGAGAGTCCAGTGAGTCCAGGCCCCTGATGCTCCAACCTCCCGGGGGGACGACGATGACAATGT GAAACCATCACAGCTGGGAAGACATTTCTGCACATGGTTCACCATGCAGTGGGCCCAAGCAAGGGGCCTATGAGGGCCTCGTTTATTAAG ATCTTTAAACTGCTTTATACACTGTCACGTGGCTTCATCAGCTGTGTGCATTTCAGGATGGTTTTTAAAGAAACCTCAGAAAGCTATTTC >16524_16524_3_CHMP1A-FANCA_CHMP1A_chr16_89723989_ENST00000397901_FANCA_chr16_89851372_ENST00000389301_length(amino acids)=1020AA_BP=18 MASLLPLRVLLLSLWPWTASFGSTRGYHGCSKKALVFLFTFLSELVPFESPRYLQVHILHPPLVPGKYRSLLTDYISLAKTRLADLKVSI ENMGLYEDLSSAGDITEPHSQALQDVEKAIMVFEHTGNIPVTVMEASIFRRPYYVSHFLPALLTPRVLPKVPDSRVAFIESLKRADKIPP SLYSTYCQACSAAEEKPEDAALGVRAEPNSAEEPLGQLTAALGELRASMTDPSQRDVISAQVAVISERLRAVLGHNEDDSSVEISKIQLS INTPRLEPREHMAVDLLLTSFCQNLMAASSVAPPERQGPWAALFVRTMCGRVLPAVLTRLCQLLRHQGPSLSAPHVLGLAALAVHLGESR SALPEVDVGPPAPGAGLPVPALFDSLLTCRTRDSLFFCLKFCTAAISYSLCKFSSQSRDTLCSCLSPGLIKKFQFLMFRLFSEARQPLSE EDVASLSWRPLHLPSADWQRAALSLWTHRTFREVLKEEDVHLTYQDWLHLELEIQPEADALSDTERQDFHQWAIHEHFLPESSASGGCDG DLQAACTILVNALMDFHQSSRSYDHSENSDLVFGGRTGNEDIISRLQEMVADLELQQDLIVPLGHTPSQEHFLFEIFRRRLQALTSGWSV AASLQRQRELLMYKRILLRLPSSVLCGSSFQAEQPITARCEQFFHLVNSEMRNFCSHGGALTQDITAHFFRGLLNACLRSRDPSLMVDFI LAKCQTKCPLILTSALVWWPSLEPVLLCRWRRHCQSPLPRELQKLQEGRQFASDFLSPEAASPAPNPDWLSAAALHFAIQQVREENIRKQ LKKLDCEREELLVFLFFFSLMGLLSSHLTSNSTTDLPKAFHVCAAILECLEKRKISWLALFQLTESDLRLGRLLLRVAPDQHTRLLPFAF YSLLSYFHEDAAIREEAFLHVAVDMYLKLVQLFVAGDTSTVSPPAGRSLELKGQGNPVELITKARLFLLQLIPRCPKKSFSHVAELLADR -------------------------------------------------------------- >16524_16524_4_CHMP1A-FANCA_CHMP1A_chr16_89723989_ENST00000397901_FANCA_chr16_89851372_ENST00000568369_length(transcript)=3475nt_BP=264nt AGCGACTCACAAAAGGTCCTCGCGCCAGCGGCGTGCGTCACCATGGCGACCGCGCGCCGCGCAGCCGCGCCCCGCCCCTCTGGCGGGACC GGCCACCATCCTCTCGCGAGAGCATCCCGTGCGACCGGAAGTGGGGCGGCGACCCCGGAAGTCCCCGCCGGGTGCAGCTTGGTCGGTTCG ATCGCCGCCGGGACCTGACACCGCCCGGAGTTGGCGTCCCTTCTCCCTCTCCGAGTGCTGCTCCTGTCATTGTGGCCATGGACGGCCTCC TTTGGGAGCACACGAGGCTACCATGGCTGCAGCAAGAAGGCCCTGGTCTTCCTGTTTACGTTCTTGTCAGAACTCGTGCCTTTTGAGTCT CCCCGGTACCTGCAGGTGCACATTCTCCACCCACCCCTGGTTCCCGGCAAGTACCGCTCCCTCCTCACAGACTACATCTCATTGGCCAAG ACACGGCTGGCCGACCTCAAGGTTTCTATAGAAAACATGGGACTCTACGAGGATTTGTCATCAGCTGGGGACATTACTGAGCCCCACAGC CAAGCTCTTCAGGATGTTGAAAAGGCCATCATGGTGTTTGAGCATACGGGGAACATCCCAGTCACCGTCATGGAGGCCAGCATATTCAGG AGGCCTTACTACGTGTCCCACTTCCTCCCCGCCCTGCTCACACCTCGAGTGCTCCCCAAAGTCCCTGACTCCCGTGTGGCGTTTATAGAG TCTCTGAAGAGAGCAGATAAAATCCCCCCATCTCTGTACTCCACCTACTGCCAGGCCTGCTCTGCTGCTGAAGAGAAGCCAGAAGATGCA GCCCTGGGAGTGAGGGCAGAACCCAACTCTGCTGAGGAGCCCCTGGGACAGCTCACAGCTGCACTGGGAGAGCTGAGAGCCTCCATGACA GACCCCAGCCAGCGTGATGTTATATCGGCACAGGTGGCAGTGATTTCTGAAAGACTGAGGGCTGTCCTGGGCCACAATGAGGATGACAGC AGCGTTGAGATATCAAAGATTCAGCTCAGCATCAACACGCCGAGACTGGAGCCACGGGAACACATGGCTGTGGACCTCCTGCTGACGTCT TTCTGTCAGAACCTGATGGCTGCCTCCAGTGTCGCTCCCCCGGAGAGGCAGGGTCCCTGGGCTGCCCTCTTCGTGAGGACCATGTGTGGA CGTGTGCTCCCTGCAGTGCTCACCCGGCTCTGCCAGCTGCTCCGTCACCAGGGCCCGAGCCTGAGTGCCCCACATGTGCTGGGGTTGGCT GCCCTGGCCGTGCACCTGGGTGAGTCCAGGTCTGCGCTCCCAGAGGTGGATGTGGGTCCTCCTGCACCTGGTGCTGGCCTTCCTGTCCCT GCGCTCTTTGACAGCCTCCTGACCTGTAGGACGAGGGATTCCTTGTTCTTCTGCCTGAAATTTTGTACAGCAGCAATTTCTTACTCTCTC TGCAAGTTTTCTTCCCAGTCACGAGATACTTTGTGCAGCTGCTTATCTCCAGGCCTTATTAAAAAGTTTCAGTTCCTCATGTTCAGATTG TTCTCAGAGGCCCGACAGCCTCTTTCTGAGGAGGACGTAGCCAGCCTTTCCTGGAGACCCTTGCACCTTCCTTCTGCAGACTGGCAGAGA GCTGCCCTCTCTCTCTGGACACACAGAACCTTCCGAGAGGTGTTGAAAGAGGAAGATGTTCACTTAACTTACCAAGACTGGTTACACCTG GAGCTGGAAATTCAACCTGAAGCTGATGCTCTTTCAGATACTGAACGGCAGGACTTCCACCAGTGGGCGATCCATGAGCACTTTCTCCCT GAGTCCTCGGCTTCAGGGGGCTGTGACGGAGACCTGCAGGCTGCGTGTACCATTCTTGTCAACGCACTGATGGATTTCCACCAAAGCTCA AGGAGTTATGACCACTCAGAAAATTCTGATTTGGTCTTTGGTGGCCGCACAGGAAATGAGGATATTATTTCCAGATTGCAGGAGATGGTA GCTGACCTGGAGCTGCAGCAAGACCTCATAGTGCCTCTCGGCCACACCCCTTCCCAGGAGCACTTCCTCTTTGAGATTTTCCGCAGACGG CTCCAGGCTCTGACAAGCGGGTGGAGCGTGGCTGCCAGCCTTCAGAGACAGAGGGAGCTGCTAATGTACAAACGGATCCTCCTCCGCCTG CCTTCGTCTGTCCTCTGCGGCAGCAGCTTCCAGGCAGAACAGCCCATCACTGCCAGATGCGAGCAGTTCTTCCACTTGGTCAACTCTGAG ATGAGAAACTTCTGCTCCCACGGAGGTGCCCTGACACAGGACATCACTGCCCACTTCTTCAGGGGCCTCCTGAACGCCTGTCTGCGGAGC AGAGACCCCTCCCTGATGGTCGACTTCATACTGGCCAAGTGCCAGACGAAATGCCCCTTAATTTTGACCTCTGCTCTGGTGTGGTGGCCG AGCCTGGAGCCTGTGCTGCTCTGCCGGTGGAGGAGACACTGCCAGAGCCCGCTGCCCCGGGAACTGCAGAAGCTACAAGAAGGCCGGCAG TTTGCCAGCGATTTCCTCTCCCCTGAGGCTGCCTCCCCAGCACCCAACCCGGACTGGCTCTCAGCTGCTGCACTGCACTTTGCGATTCAA CAAGTCAGGGAAGAAAACATCAGGAAGCAGCTAAAGAAGCTGGACTGCGAGAGAGAGGAGCTATTGGTTTTCCTTTTCTTCTTCTCCTTG ATGGGCCTGCTGTCGTCACATCTGACCTCAAATAGCACCACAGACCTGCCAAAGGCTTTCCACGTTTGTGCAGCAATCCTCGAGTGTTTA GAGAAGAGGAAGATATCCTGGCTGGCACTCTTTCAGTTGACAGAGAGTGACCTCAGGCTGGGGCGGCTCCTCCTCCGTGTGGCCCCGGAT CAGCACACCAGGCTGCTGCCTTTCGCTTTTTACAGTCTTCTCTCCTACTTCCATGAAGACGCGGCCATCAGGGAAGAGGCCTTCCTGCAT GTTGCTGTGGACATGTACTTGAAGCTGGTCCAGCTCTTCGTGGCTGGGGATACAAGCACAGTTTCACCTCCAGCTGGCAGGAGCCTGGAG CTCAAGGGTCAGGCAGGGCAACCCCGTGGAACTGATAACAAAAGCTCGTCTTTTTCTGCTGCAGTTAATACCTCGGTGCCCGAAAAAGAG CTTCTCACACGTGGCAGAGCTGCTGGCTGATCGTGGGGACTGCGACCCAGAGGTGAGCGCCGCCCTCCAGAGCAGACAGCAGGCTGCCCC TGACGCTGACCTGTCCCAGGAGCCTCATCTCTTCTGACGGGACCTGCCACTGCACACCAGCCCAGCTCCCGTGTAAATAATTTATTACAA GCATAACATGGAGCTCTTGTTGCACTAAAAAGTGGATTACAAATCTCCTCGACTGCTTTAGTGGGGAAAGGAATCAATTATTTATGAACT >16524_16524_4_CHMP1A-FANCA_CHMP1A_chr16_89723989_ENST00000397901_FANCA_chr16_89851372_ENST00000568369_length(amino acids)=989AA_BP=18 MASLLPLRVLLLSLWPWTASFGSTRGYHGCSKKALVFLFTFLSELVPFESPRYLQVHILHPPLVPGKYRSLLTDYISLAKTRLADLKVSI ENMGLYEDLSSAGDITEPHSQALQDVEKAIMVFEHTGNIPVTVMEASIFRRPYYVSHFLPALLTPRVLPKVPDSRVAFIESLKRADKIPP SLYSTYCQACSAAEEKPEDAALGVRAEPNSAEEPLGQLTAALGELRASMTDPSQRDVISAQVAVISERLRAVLGHNEDDSSVEISKIQLS INTPRLEPREHMAVDLLLTSFCQNLMAASSVAPPERQGPWAALFVRTMCGRVLPAVLTRLCQLLRHQGPSLSAPHVLGLAALAVHLGESR SALPEVDVGPPAPGAGLPVPALFDSLLTCRTRDSLFFCLKFCTAAISYSLCKFSSQSRDTLCSCLSPGLIKKFQFLMFRLFSEARQPLSE EDVASLSWRPLHLPSADWQRAALSLWTHRTFREVLKEEDVHLTYQDWLHLELEIQPEADALSDTERQDFHQWAIHEHFLPESSASGGCDG DLQAACTILVNALMDFHQSSRSYDHSENSDLVFGGRTGNEDIISRLQEMVADLELQQDLIVPLGHTPSQEHFLFEIFRRRLQALTSGWSV AASLQRQRELLMYKRILLRLPSSVLCGSSFQAEQPITARCEQFFHLVNSEMRNFCSHGGALTQDITAHFFRGLLNACLRSRDPSLMVDFI LAKCQTKCPLILTSALVWWPSLEPVLLCRWRRHCQSPLPRELQKLQEGRQFASDFLSPEAASPAPNPDWLSAAALHFAIQQVREENIRKQ LKKLDCEREELLVFLFFFSLMGLLSSHLTSNSTTDLPKAFHVCAAILECLEKRKISWLALFQLTESDLRLGRLLLRVAPDQHTRLLPFAF -------------------------------------------------------------- >16524_16524_5_CHMP1A-FANCA_CHMP1A_chr16_89723989_ENST00000550102_FANCA_chr16_89851372_ENST00000389301_length(transcript)=4130nt_BP=69nt TGACACCGCCCGGAGTTGGCGTCCCTTCTCCCTCTCCGAGTGCTGCTCCTGTCATTGTGGCCATGGACGGCCTCCTTTGGGAGCACACGA GGCTACCATGGCTGCAGCAAGAAGGCCCTGGTCTTCCTGTTTACGTTCTTGTCAGAACTCGTGCCTTTTGAGTCTCCCCGGTACCTGCAG GTGCACATTCTCCACCCACCCCTGGTTCCCGGCAAGTACCGCTCCCTCCTCACAGACTACATCTCATTGGCCAAGACACGGCTGGCCGAC CTCAAGGTTTCTATAGAAAACATGGGACTCTACGAGGATTTGTCATCAGCTGGGGACATTACTGAGCCCCACAGCCAAGCTCTTCAGGAT GTTGAAAAGGCCATCATGGTGTTTGAGCATACGGGGAACATCCCAGTCACCGTCATGGAGGCCAGCATATTCAGGAGGCCTTACTACGTG TCCCACTTCCTCCCCGCCCTGCTCACACCTCGAGTGCTCCCCAAAGTCCCTGACTCCCGTGTGGCGTTTATAGAGTCTCTGAAGAGAGCA GATAAAATCCCCCCATCTCTGTACTCCACCTACTGCCAGGCCTGCTCTGCTGCTGAAGAGAAGCCAGAAGATGCAGCCCTGGGAGTGAGG GCAGAACCCAACTCTGCTGAGGAGCCCCTGGGACAGCTCACAGCTGCACTGGGAGAGCTGAGAGCCTCCATGACAGACCCCAGCCAGCGT GATGTTATATCGGCACAGGTGGCAGTGATTTCTGAAAGACTGAGGGCTGTCCTGGGCCACAATGAGGATGACAGCAGCGTTGAGATATCA AAGATTCAGCTCAGCATCAACACGCCGAGACTGGAGCCACGGGAACACATGGCTGTGGACCTCCTGCTGACGTCTTTCTGTCAGAACCTG ATGGCTGCCTCCAGTGTCGCTCCCCCGGAGAGGCAGGGTCCCTGGGCTGCCCTCTTCGTGAGGACCATGTGTGGACGTGTGCTCCCTGCA GTGCTCACCCGGCTCTGCCAGCTGCTCCGTCACCAGGGCCCGAGCCTGAGTGCCCCACATGTGCTGGGGTTGGCTGCCCTGGCCGTGCAC CTGGGTGAGTCCAGGTCTGCGCTCCCAGAGGTGGATGTGGGTCCTCCTGCACCTGGTGCTGGCCTTCCTGTCCCTGCGCTCTTTGACAGC CTCCTGACCTGTAGGACGAGGGATTCCTTGTTCTTCTGCCTGAAATTTTGTACAGCAGCAATTTCTTACTCTCTCTGCAAGTTTTCTTCC CAGTCACGAGATACTTTGTGCAGCTGCTTATCTCCAGGCCTTATTAAAAAGTTTCAGTTCCTCATGTTCAGATTGTTCTCAGAGGCCCGA CAGCCTCTTTCTGAGGAGGACGTAGCCAGCCTTTCCTGGAGACCCTTGCACCTTCCTTCTGCAGACTGGCAGAGAGCTGCCCTCTCTCTC TGGACACACAGAACCTTCCGAGAGGTGTTGAAAGAGGAAGATGTTCACTTAACTTACCAAGACTGGTTACACCTGGAGCTGGAAATTCAA CCTGAAGCTGATGCTCTTTCAGATACTGAACGGCAGGACTTCCACCAGTGGGCGATCCATGAGCACTTTCTCCCTGAGTCCTCGGCTTCA GGGGGCTGTGACGGAGACCTGCAGGCTGCGTGTACCATTCTTGTCAACGCACTGATGGATTTCCACCAAAGCTCAAGGAGTTATGACCAC TCAGAAAATTCTGATTTGGTCTTTGGTGGCCGCACAGGAAATGAGGATATTATTTCCAGATTGCAGGAGATGGTAGCTGACCTGGAGCTG CAGCAAGACCTCATAGTGCCTCTCGGCCACACCCCTTCCCAGGAGCACTTCCTCTTTGAGATTTTCCGCAGACGGCTCCAGGCTCTGACA AGCGGGTGGAGCGTGGCTGCCAGCCTTCAGAGACAGAGGGAGCTGCTAATGTACAAACGGATCCTCCTCCGCCTGCCTTCGTCTGTCCTC TGCGGCAGCAGCTTCCAGGCAGAACAGCCCATCACTGCCAGATGCGAGCAGTTCTTCCACTTGGTCAACTCTGAGATGAGAAACTTCTGC TCCCACGGAGGTGCCCTGACACAGGACATCACTGCCCACTTCTTCAGGGGCCTCCTGAACGCCTGTCTGCGGAGCAGAGACCCCTCCCTG ATGGTCGACTTCATACTGGCCAAGTGCCAGACGAAATGCCCCTTAATTTTGACCTCTGCTCTGGTGTGGTGGCCGAGCCTGGAGCCTGTG CTGCTCTGCCGGTGGAGGAGACACTGCCAGAGCCCGCTGCCCCGGGAACTGCAGAAGCTACAAGAAGGCCGGCAGTTTGCCAGCGATTTC CTCTCCCCTGAGGCTGCCTCCCCAGCACCCAACCCGGACTGGCTCTCAGCTGCTGCACTGCACTTTGCGATTCAACAAGTCAGGGAAGAA AACATCAGGAAGCAGCTAAAGAAGCTGGACTGCGAGAGAGAGGAGCTATTGGTTTTCCTTTTCTTCTTCTCCTTGATGGGCCTGCTGTCG TCACATCTGACCTCAAATAGCACCACAGACCTGCCAAAGGCTTTCCACGTTTGTGCAGCAATCCTCGAGTGTTTAGAGAAGAGGAAGATA TCCTGGCTGGCACTCTTTCAGTTGACAGAGAGTGACCTCAGGCTGGGGCGGCTCCTCCTCCGTGTGGCCCCGGATCAGCACACCAGGCTG CTGCCTTTCGCTTTTTACAGTCTTCTCTCCTACTTCCATGAAGACGCGGCCATCAGGGAAGAGGCCTTCCTGCATGTTGCTGTGGACATG TACTTGAAGCTGGTCCAGCTCTTCGTGGCTGGGGATACAAGCACAGTTTCACCTCCAGCTGGCAGGAGCCTGGAGCTCAAGGGTCAGGGC AACCCCGTGGAACTGATAACAAAAGCTCGTCTTTTTCTGCTGCAGTTAATACCTCGGTGCCCGAAAAAGAGCTTCTCACACGTGGCAGAG CTGCTGGCTGATCGTGGGGACTGCGACCCAGAGGTGAGCGCCGCCCTCCAGAGCAGACAGCAGGCTGCCCCTGACGCTGACCTGTCCCAG GAGCCTCATCTCTTCTGACGGGACCTGCCACTGCACACCAGCCCAGCTCCCGTGTAAATAATTTATTACAAGCATAACATGGAGCTCTTG TTGCACTAAAAAGTGGATTACAAATCTCCTCGACTGCTTTAGTGGGGAAAGGAATCAATTATTTATGAACTGTCCGGCCCCGAGTCACTC AGCGTTTGCGGGAAAATAAACCACTGGTCCCAGAGCAGAGGAAGGCTACTTGAGCCGGACACCAAGCCCGCCTCCAGCACCAAGGGCGGG CAGCACCCTCCGACCCTCCCATGCGGGTGCACACGAAGGGTGAGGCTGACACAGCCACTGCGGAGTCCAGGCTGCTAGAGGTGCTCATCC TCACTGCCGTCCTCAGGTGGGTTCGGGCTTCACCGCCTGGCCCTCTGTGGTCACAGAGGGGCTCGGTGGCCCAGGTGGTGGTTCCGCCTC CAGGGGCAGGGCCTTGTCCTGGGTCTGTGTCAGCGGGTGCACCATGGACATGTGTACATTGAGGTTGTGGGCCTTCTCAAACCGCCGGCC ACACTGGTCACAGGCAAAGTCCAGCTCAGTCTCAGCCTTGTGTTTGGTCATGTGGTACTTGAGGGATGCCCGCTGCCTGCACTGGAACCC ACAGACCTCACACCTGGGGGACAGAGGCAGATAAGAAGGTGCGAGGGCCACAGCCCTGGGAGGGGGTCCTGACTCACACTTACTGCAAAG GCTTGGCTCCCGAATGTCGCATTTGGTGGACGAGAAGGTGCTTCCGCTGCTTGAAGGTTTGTCCACATTCGTCACAGATATAGTTCCGCA CCTCTGAGAGGGGAGAGTCCAGTGAGTCCAGGCCCCTGATGCTCCAACCTCCCGGGGGGACGACGATGACAATGTGAAACCATCACAGCT GGGAAGACATTTCTGCACATGGTTCACCATGCAGTGGGCCCAAGCAAGGGGCCTATGAGGGCCTCGTTTATTAAGATCTTTAAACTGCTT >16524_16524_5_CHMP1A-FANCA_CHMP1A_chr16_89723989_ENST00000550102_FANCA_chr16_89851372_ENST00000389301_length(amino acids)=1020AA_BP=18 MASLLPLRVLLLSLWPWTASFGSTRGYHGCSKKALVFLFTFLSELVPFESPRYLQVHILHPPLVPGKYRSLLTDYISLAKTRLADLKVSI ENMGLYEDLSSAGDITEPHSQALQDVEKAIMVFEHTGNIPVTVMEASIFRRPYYVSHFLPALLTPRVLPKVPDSRVAFIESLKRADKIPP SLYSTYCQACSAAEEKPEDAALGVRAEPNSAEEPLGQLTAALGELRASMTDPSQRDVISAQVAVISERLRAVLGHNEDDSSVEISKIQLS INTPRLEPREHMAVDLLLTSFCQNLMAASSVAPPERQGPWAALFVRTMCGRVLPAVLTRLCQLLRHQGPSLSAPHVLGLAALAVHLGESR SALPEVDVGPPAPGAGLPVPALFDSLLTCRTRDSLFFCLKFCTAAISYSLCKFSSQSRDTLCSCLSPGLIKKFQFLMFRLFSEARQPLSE EDVASLSWRPLHLPSADWQRAALSLWTHRTFREVLKEEDVHLTYQDWLHLELEIQPEADALSDTERQDFHQWAIHEHFLPESSASGGCDG DLQAACTILVNALMDFHQSSRSYDHSENSDLVFGGRTGNEDIISRLQEMVADLELQQDLIVPLGHTPSQEHFLFEIFRRRLQALTSGWSV AASLQRQRELLMYKRILLRLPSSVLCGSSFQAEQPITARCEQFFHLVNSEMRNFCSHGGALTQDITAHFFRGLLNACLRSRDPSLMVDFI LAKCQTKCPLILTSALVWWPSLEPVLLCRWRRHCQSPLPRELQKLQEGRQFASDFLSPEAASPAPNPDWLSAAALHFAIQQVREENIRKQ LKKLDCEREELLVFLFFFSLMGLLSSHLTSNSTTDLPKAFHVCAAILECLEKRKISWLALFQLTESDLRLGRLLLRVAPDQHTRLLPFAF YSLLSYFHEDAAIREEAFLHVAVDMYLKLVQLFVAGDTSTVSPPAGRSLELKGQGNPVELITKARLFLLQLIPRCPKKSFSHVAELLADR -------------------------------------------------------------- >16524_16524_6_CHMP1A-FANCA_CHMP1A_chr16_89723989_ENST00000550102_FANCA_chr16_89851372_ENST00000568369_length(transcript)=3280nt_BP=69nt TGACACCGCCCGGAGTTGGCGTCCCTTCTCCCTCTCCGAGTGCTGCTCCTGTCATTGTGGCCATGGACGGCCTCCTTTGGGAGCACACGA GGCTACCATGGCTGCAGCAAGAAGGCCCTGGTCTTCCTGTTTACGTTCTTGTCAGAACTCGTGCCTTTTGAGTCTCCCCGGTACCTGCAG GTGCACATTCTCCACCCACCCCTGGTTCCCGGCAAGTACCGCTCCCTCCTCACAGACTACATCTCATTGGCCAAGACACGGCTGGCCGAC CTCAAGGTTTCTATAGAAAACATGGGACTCTACGAGGATTTGTCATCAGCTGGGGACATTACTGAGCCCCACAGCCAAGCTCTTCAGGAT GTTGAAAAGGCCATCATGGTGTTTGAGCATACGGGGAACATCCCAGTCACCGTCATGGAGGCCAGCATATTCAGGAGGCCTTACTACGTG TCCCACTTCCTCCCCGCCCTGCTCACACCTCGAGTGCTCCCCAAAGTCCCTGACTCCCGTGTGGCGTTTATAGAGTCTCTGAAGAGAGCA GATAAAATCCCCCCATCTCTGTACTCCACCTACTGCCAGGCCTGCTCTGCTGCTGAAGAGAAGCCAGAAGATGCAGCCCTGGGAGTGAGG GCAGAACCCAACTCTGCTGAGGAGCCCCTGGGACAGCTCACAGCTGCACTGGGAGAGCTGAGAGCCTCCATGACAGACCCCAGCCAGCGT GATGTTATATCGGCACAGGTGGCAGTGATTTCTGAAAGACTGAGGGCTGTCCTGGGCCACAATGAGGATGACAGCAGCGTTGAGATATCA AAGATTCAGCTCAGCATCAACACGCCGAGACTGGAGCCACGGGAACACATGGCTGTGGACCTCCTGCTGACGTCTTTCTGTCAGAACCTG ATGGCTGCCTCCAGTGTCGCTCCCCCGGAGAGGCAGGGTCCCTGGGCTGCCCTCTTCGTGAGGACCATGTGTGGACGTGTGCTCCCTGCA GTGCTCACCCGGCTCTGCCAGCTGCTCCGTCACCAGGGCCCGAGCCTGAGTGCCCCACATGTGCTGGGGTTGGCTGCCCTGGCCGTGCAC CTGGGTGAGTCCAGGTCTGCGCTCCCAGAGGTGGATGTGGGTCCTCCTGCACCTGGTGCTGGCCTTCCTGTCCCTGCGCTCTTTGACAGC CTCCTGACCTGTAGGACGAGGGATTCCTTGTTCTTCTGCCTGAAATTTTGTACAGCAGCAATTTCTTACTCTCTCTGCAAGTTTTCTTCC CAGTCACGAGATACTTTGTGCAGCTGCTTATCTCCAGGCCTTATTAAAAAGTTTCAGTTCCTCATGTTCAGATTGTTCTCAGAGGCCCGA CAGCCTCTTTCTGAGGAGGACGTAGCCAGCCTTTCCTGGAGACCCTTGCACCTTCCTTCTGCAGACTGGCAGAGAGCTGCCCTCTCTCTC TGGACACACAGAACCTTCCGAGAGGTGTTGAAAGAGGAAGATGTTCACTTAACTTACCAAGACTGGTTACACCTGGAGCTGGAAATTCAA CCTGAAGCTGATGCTCTTTCAGATACTGAACGGCAGGACTTCCACCAGTGGGCGATCCATGAGCACTTTCTCCCTGAGTCCTCGGCTTCA GGGGGCTGTGACGGAGACCTGCAGGCTGCGTGTACCATTCTTGTCAACGCACTGATGGATTTCCACCAAAGCTCAAGGAGTTATGACCAC TCAGAAAATTCTGATTTGGTCTTTGGTGGCCGCACAGGAAATGAGGATATTATTTCCAGATTGCAGGAGATGGTAGCTGACCTGGAGCTG CAGCAAGACCTCATAGTGCCTCTCGGCCACACCCCTTCCCAGGAGCACTTCCTCTTTGAGATTTTCCGCAGACGGCTCCAGGCTCTGACA AGCGGGTGGAGCGTGGCTGCCAGCCTTCAGAGACAGAGGGAGCTGCTAATGTACAAACGGATCCTCCTCCGCCTGCCTTCGTCTGTCCTC TGCGGCAGCAGCTTCCAGGCAGAACAGCCCATCACTGCCAGATGCGAGCAGTTCTTCCACTTGGTCAACTCTGAGATGAGAAACTTCTGC TCCCACGGAGGTGCCCTGACACAGGACATCACTGCCCACTTCTTCAGGGGCCTCCTGAACGCCTGTCTGCGGAGCAGAGACCCCTCCCTG ATGGTCGACTTCATACTGGCCAAGTGCCAGACGAAATGCCCCTTAATTTTGACCTCTGCTCTGGTGTGGTGGCCGAGCCTGGAGCCTGTG CTGCTCTGCCGGTGGAGGAGACACTGCCAGAGCCCGCTGCCCCGGGAACTGCAGAAGCTACAAGAAGGCCGGCAGTTTGCCAGCGATTTC CTCTCCCCTGAGGCTGCCTCCCCAGCACCCAACCCGGACTGGCTCTCAGCTGCTGCACTGCACTTTGCGATTCAACAAGTCAGGGAAGAA AACATCAGGAAGCAGCTAAAGAAGCTGGACTGCGAGAGAGAGGAGCTATTGGTTTTCCTTTTCTTCTTCTCCTTGATGGGCCTGCTGTCG TCACATCTGACCTCAAATAGCACCACAGACCTGCCAAAGGCTTTCCACGTTTGTGCAGCAATCCTCGAGTGTTTAGAGAAGAGGAAGATA TCCTGGCTGGCACTCTTTCAGTTGACAGAGAGTGACCTCAGGCTGGGGCGGCTCCTCCTCCGTGTGGCCCCGGATCAGCACACCAGGCTG CTGCCTTTCGCTTTTTACAGTCTTCTCTCCTACTTCCATGAAGACGCGGCCATCAGGGAAGAGGCCTTCCTGCATGTTGCTGTGGACATG TACTTGAAGCTGGTCCAGCTCTTCGTGGCTGGGGATACAAGCACAGTTTCACCTCCAGCTGGCAGGAGCCTGGAGCTCAAGGGTCAGGCA GGGCAACCCCGTGGAACTGATAACAAAAGCTCGTCTTTTTCTGCTGCAGTTAATACCTCGGTGCCCGAAAAAGAGCTTCTCACACGTGGC AGAGCTGCTGGCTGATCGTGGGGACTGCGACCCAGAGGTGAGCGCCGCCCTCCAGAGCAGACAGCAGGCTGCCCCTGACGCTGACCTGTC CCAGGAGCCTCATCTCTTCTGACGGGACCTGCCACTGCACACCAGCCCAGCTCCCGTGTAAATAATTTATTACAAGCATAACATGGAGCT CTTGTTGCACTAAAAAGTGGATTACAAATCTCCTCGACTGCTTTAGTGGGGAAAGGAATCAATTATTTATGAACTGTCCGGCCCCGAGTC >16524_16524_6_CHMP1A-FANCA_CHMP1A_chr16_89723989_ENST00000550102_FANCA_chr16_89851372_ENST00000568369_length(amino acids)=989AA_BP=18 MASLLPLRVLLLSLWPWTASFGSTRGYHGCSKKALVFLFTFLSELVPFESPRYLQVHILHPPLVPGKYRSLLTDYISLAKTRLADLKVSI ENMGLYEDLSSAGDITEPHSQALQDVEKAIMVFEHTGNIPVTVMEASIFRRPYYVSHFLPALLTPRVLPKVPDSRVAFIESLKRADKIPP SLYSTYCQACSAAEEKPEDAALGVRAEPNSAEEPLGQLTAALGELRASMTDPSQRDVISAQVAVISERLRAVLGHNEDDSSVEISKIQLS INTPRLEPREHMAVDLLLTSFCQNLMAASSVAPPERQGPWAALFVRTMCGRVLPAVLTRLCQLLRHQGPSLSAPHVLGLAALAVHLGESR SALPEVDVGPPAPGAGLPVPALFDSLLTCRTRDSLFFCLKFCTAAISYSLCKFSSQSRDTLCSCLSPGLIKKFQFLMFRLFSEARQPLSE EDVASLSWRPLHLPSADWQRAALSLWTHRTFREVLKEEDVHLTYQDWLHLELEIQPEADALSDTERQDFHQWAIHEHFLPESSASGGCDG DLQAACTILVNALMDFHQSSRSYDHSENSDLVFGGRTGNEDIISRLQEMVADLELQQDLIVPLGHTPSQEHFLFEIFRRRLQALTSGWSV AASLQRQRELLMYKRILLRLPSSVLCGSSFQAEQPITARCEQFFHLVNSEMRNFCSHGGALTQDITAHFFRGLLNACLRSRDPSLMVDFI LAKCQTKCPLILTSALVWWPSLEPVLLCRWRRHCQSPLPRELQKLQEGRQFASDFLSPEAASPAPNPDWLSAAALHFAIQQVREENIRKQ LKKLDCEREELLVFLFFFSLMGLLSSHLTSNSTTDLPKAFHVCAAILECLEKRKISWLALFQLTESDLRLGRLLLRVAPDQHTRLLPFAF -------------------------------------------------------------- >16524_16524_7_CHMP1A-FANCA_CHMP1A_chr16_89723990_ENST00000253475_FANCA_chr16_89851372_ENST00000389301_length(transcript)=4201nt_BP=140nt CCGGAAGTGGGGCGGCGACCCCGGAAGTCCCCGCCGGGTGCAGCTTGGTCGGTTCGATCGCCGCCGGGACCTGACACCGCCCGGAGTTGG CGTCCCTTCTCCCTCTCCGAGTGCTGCTCCTGTCATTGTGGCCATGGACGGCCTCCTTTGGGAGCACACGAGGCTACCATGGCTGCAGCA AGAAGGCCCTGGTCTTCCTGTTTACGTTCTTGTCAGAACTCGTGCCTTTTGAGTCTCCCCGGTACCTGCAGGTGCACATTCTCCACCCAC CCCTGGTTCCCGGCAAGTACCGCTCCCTCCTCACAGACTACATCTCATTGGCCAAGACACGGCTGGCCGACCTCAAGGTTTCTATAGAAA ACATGGGACTCTACGAGGATTTGTCATCAGCTGGGGACATTACTGAGCCCCACAGCCAAGCTCTTCAGGATGTTGAAAAGGCCATCATGG TGTTTGAGCATACGGGGAACATCCCAGTCACCGTCATGGAGGCCAGCATATTCAGGAGGCCTTACTACGTGTCCCACTTCCTCCCCGCCC TGCTCACACCTCGAGTGCTCCCCAAAGTCCCTGACTCCCGTGTGGCGTTTATAGAGTCTCTGAAGAGAGCAGATAAAATCCCCCCATCTC TGTACTCCACCTACTGCCAGGCCTGCTCTGCTGCTGAAGAGAAGCCAGAAGATGCAGCCCTGGGAGTGAGGGCAGAACCCAACTCTGCTG AGGAGCCCCTGGGACAGCTCACAGCTGCACTGGGAGAGCTGAGAGCCTCCATGACAGACCCCAGCCAGCGTGATGTTATATCGGCACAGG TGGCAGTGATTTCTGAAAGACTGAGGGCTGTCCTGGGCCACAATGAGGATGACAGCAGCGTTGAGATATCAAAGATTCAGCTCAGCATCA ACACGCCGAGACTGGAGCCACGGGAACACATGGCTGTGGACCTCCTGCTGACGTCTTTCTGTCAGAACCTGATGGCTGCCTCCAGTGTCG CTCCCCCGGAGAGGCAGGGTCCCTGGGCTGCCCTCTTCGTGAGGACCATGTGTGGACGTGTGCTCCCTGCAGTGCTCACCCGGCTCTGCC AGCTGCTCCGTCACCAGGGCCCGAGCCTGAGTGCCCCACATGTGCTGGGGTTGGCTGCCCTGGCCGTGCACCTGGGTGAGTCCAGGTCTG CGCTCCCAGAGGTGGATGTGGGTCCTCCTGCACCTGGTGCTGGCCTTCCTGTCCCTGCGCTCTTTGACAGCCTCCTGACCTGTAGGACGA GGGATTCCTTGTTCTTCTGCCTGAAATTTTGTACAGCAGCAATTTCTTACTCTCTCTGCAAGTTTTCTTCCCAGTCACGAGATACTTTGT GCAGCTGCTTATCTCCAGGCCTTATTAAAAAGTTTCAGTTCCTCATGTTCAGATTGTTCTCAGAGGCCCGACAGCCTCTTTCTGAGGAGG ACGTAGCCAGCCTTTCCTGGAGACCCTTGCACCTTCCTTCTGCAGACTGGCAGAGAGCTGCCCTCTCTCTCTGGACACACAGAACCTTCC GAGAGGTGTTGAAAGAGGAAGATGTTCACTTAACTTACCAAGACTGGTTACACCTGGAGCTGGAAATTCAACCTGAAGCTGATGCTCTTT CAGATACTGAACGGCAGGACTTCCACCAGTGGGCGATCCATGAGCACTTTCTCCCTGAGTCCTCGGCTTCAGGGGGCTGTGACGGAGACC TGCAGGCTGCGTGTACCATTCTTGTCAACGCACTGATGGATTTCCACCAAAGCTCAAGGAGTTATGACCACTCAGAAAATTCTGATTTGG TCTTTGGTGGCCGCACAGGAAATGAGGATATTATTTCCAGATTGCAGGAGATGGTAGCTGACCTGGAGCTGCAGCAAGACCTCATAGTGC CTCTCGGCCACACCCCTTCCCAGGAGCACTTCCTCTTTGAGATTTTCCGCAGACGGCTCCAGGCTCTGACAAGCGGGTGGAGCGTGGCTG CCAGCCTTCAGAGACAGAGGGAGCTGCTAATGTACAAACGGATCCTCCTCCGCCTGCCTTCGTCTGTCCTCTGCGGCAGCAGCTTCCAGG CAGAACAGCCCATCACTGCCAGATGCGAGCAGTTCTTCCACTTGGTCAACTCTGAGATGAGAAACTTCTGCTCCCACGGAGGTGCCCTGA CACAGGACATCACTGCCCACTTCTTCAGGGGCCTCCTGAACGCCTGTCTGCGGAGCAGAGACCCCTCCCTGATGGTCGACTTCATACTGG CCAAGTGCCAGACGAAATGCCCCTTAATTTTGACCTCTGCTCTGGTGTGGTGGCCGAGCCTGGAGCCTGTGCTGCTCTGCCGGTGGAGGA GACACTGCCAGAGCCCGCTGCCCCGGGAACTGCAGAAGCTACAAGAAGGCCGGCAGTTTGCCAGCGATTTCCTCTCCCCTGAGGCTGCCT CCCCAGCACCCAACCCGGACTGGCTCTCAGCTGCTGCACTGCACTTTGCGATTCAACAAGTCAGGGAAGAAAACATCAGGAAGCAGCTAA AGAAGCTGGACTGCGAGAGAGAGGAGCTATTGGTTTTCCTTTTCTTCTTCTCCTTGATGGGCCTGCTGTCGTCACATCTGACCTCAAATA GCACCACAGACCTGCCAAAGGCTTTCCACGTTTGTGCAGCAATCCTCGAGTGTTTAGAGAAGAGGAAGATATCCTGGCTGGCACTCTTTC AGTTGACAGAGAGTGACCTCAGGCTGGGGCGGCTCCTCCTCCGTGTGGCCCCGGATCAGCACACCAGGCTGCTGCCTTTCGCTTTTTACA GTCTTCTCTCCTACTTCCATGAAGACGCGGCCATCAGGGAAGAGGCCTTCCTGCATGTTGCTGTGGACATGTACTTGAAGCTGGTCCAGC TCTTCGTGGCTGGGGATACAAGCACAGTTTCACCTCCAGCTGGCAGGAGCCTGGAGCTCAAGGGTCAGGGCAACCCCGTGGAACTGATAA CAAAAGCTCGTCTTTTTCTGCTGCAGTTAATACCTCGGTGCCCGAAAAAGAGCTTCTCACACGTGGCAGAGCTGCTGGCTGATCGTGGGG ACTGCGACCCAGAGGTGAGCGCCGCCCTCCAGAGCAGACAGCAGGCTGCCCCTGACGCTGACCTGTCCCAGGAGCCTCATCTCTTCTGAC GGGACCTGCCACTGCACACCAGCCCAGCTCCCGTGTAAATAATTTATTACAAGCATAACATGGAGCTCTTGTTGCACTAAAAAGTGGATT ACAAATCTCCTCGACTGCTTTAGTGGGGAAAGGAATCAATTATTTATGAACTGTCCGGCCCCGAGTCACTCAGCGTTTGCGGGAAAATAA ACCACTGGTCCCAGAGCAGAGGAAGGCTACTTGAGCCGGACACCAAGCCCGCCTCCAGCACCAAGGGCGGGCAGCACCCTCCGACCCTCC CATGCGGGTGCACACGAAGGGTGAGGCTGACACAGCCACTGCGGAGTCCAGGCTGCTAGAGGTGCTCATCCTCACTGCCGTCCTCAGGTG GGTTCGGGCTTCACCGCCTGGCCCTCTGTGGTCACAGAGGGGCTCGGTGGCCCAGGTGGTGGTTCCGCCTCCAGGGGCAGGGCCTTGTCC TGGGTCTGTGTCAGCGGGTGCACCATGGACATGTGTACATTGAGGTTGTGGGCCTTCTCAAACCGCCGGCCACACTGGTCACAGGCAAAG TCCAGCTCAGTCTCAGCCTTGTGTTTGGTCATGTGGTACTTGAGGGATGCCCGCTGCCTGCACTGGAACCCACAGACCTCACACCTGGGG GACAGAGGCAGATAAGAAGGTGCGAGGGCCACAGCCCTGGGAGGGGGTCCTGACTCACACTTACTGCAAAGGCTTGGCTCCCGAATGTCG CATTTGGTGGACGAGAAGGTGCTTCCGCTGCTTGAAGGTTTGTCCACATTCGTCACAGATATAGTTCCGCACCTCTGAGAGGGGAGAGTC CAGTGAGTCCAGGCCCCTGATGCTCCAACCTCCCGGGGGGACGACGATGACAATGTGAAACCATCACAGCTGGGAAGACATTTCTGCACA TGGTTCACCATGCAGTGGGCCCAAGCAAGGGGCCTATGAGGGCCTCGTTTATTAAGATCTTTAAACTGCTTTATACACTGTCACGTGGCT >16524_16524_7_CHMP1A-FANCA_CHMP1A_chr16_89723990_ENST00000253475_FANCA_chr16_89851372_ENST00000389301_length(amino acids)=1020AA_BP=18 MASLLPLRVLLLSLWPWTASFGSTRGYHGCSKKALVFLFTFLSELVPFESPRYLQVHILHPPLVPGKYRSLLTDYISLAKTRLADLKVSI ENMGLYEDLSSAGDITEPHSQALQDVEKAIMVFEHTGNIPVTVMEASIFRRPYYVSHFLPALLTPRVLPKVPDSRVAFIESLKRADKIPP SLYSTYCQACSAAEEKPEDAALGVRAEPNSAEEPLGQLTAALGELRASMTDPSQRDVISAQVAVISERLRAVLGHNEDDSSVEISKIQLS INTPRLEPREHMAVDLLLTSFCQNLMAASSVAPPERQGPWAALFVRTMCGRVLPAVLTRLCQLLRHQGPSLSAPHVLGLAALAVHLGESR SALPEVDVGPPAPGAGLPVPALFDSLLTCRTRDSLFFCLKFCTAAISYSLCKFSSQSRDTLCSCLSPGLIKKFQFLMFRLFSEARQPLSE EDVASLSWRPLHLPSADWQRAALSLWTHRTFREVLKEEDVHLTYQDWLHLELEIQPEADALSDTERQDFHQWAIHEHFLPESSASGGCDG DLQAACTILVNALMDFHQSSRSYDHSENSDLVFGGRTGNEDIISRLQEMVADLELQQDLIVPLGHTPSQEHFLFEIFRRRLQALTSGWSV AASLQRQRELLMYKRILLRLPSSVLCGSSFQAEQPITARCEQFFHLVNSEMRNFCSHGGALTQDITAHFFRGLLNACLRSRDPSLMVDFI LAKCQTKCPLILTSALVWWPSLEPVLLCRWRRHCQSPLPRELQKLQEGRQFASDFLSPEAASPAPNPDWLSAAALHFAIQQVREENIRKQ LKKLDCEREELLVFLFFFSLMGLLSSHLTSNSTTDLPKAFHVCAAILECLEKRKISWLALFQLTESDLRLGRLLLRVAPDQHTRLLPFAF YSLLSYFHEDAAIREEAFLHVAVDMYLKLVQLFVAGDTSTVSPPAGRSLELKGQGNPVELITKARLFLLQLIPRCPKKSFSHVAELLADR -------------------------------------------------------------- >16524_16524_8_CHMP1A-FANCA_CHMP1A_chr16_89723990_ENST00000253475_FANCA_chr16_89851372_ENST00000568369_length(transcript)=3351nt_BP=140nt CCGGAAGTGGGGCGGCGACCCCGGAAGTCCCCGCCGGGTGCAGCTTGGTCGGTTCGATCGCCGCCGGGACCTGACACCGCCCGGAGTTGG CGTCCCTTCTCCCTCTCCGAGTGCTGCTCCTGTCATTGTGGCCATGGACGGCCTCCTTTGGGAGCACACGAGGCTACCATGGCTGCAGCA AGAAGGCCCTGGTCTTCCTGTTTACGTTCTTGTCAGAACTCGTGCCTTTTGAGTCTCCCCGGTACCTGCAGGTGCACATTCTCCACCCAC CCCTGGTTCCCGGCAAGTACCGCTCCCTCCTCACAGACTACATCTCATTGGCCAAGACACGGCTGGCCGACCTCAAGGTTTCTATAGAAA ACATGGGACTCTACGAGGATTTGTCATCAGCTGGGGACATTACTGAGCCCCACAGCCAAGCTCTTCAGGATGTTGAAAAGGCCATCATGG TGTTTGAGCATACGGGGAACATCCCAGTCACCGTCATGGAGGCCAGCATATTCAGGAGGCCTTACTACGTGTCCCACTTCCTCCCCGCCC TGCTCACACCTCGAGTGCTCCCCAAAGTCCCTGACTCCCGTGTGGCGTTTATAGAGTCTCTGAAGAGAGCAGATAAAATCCCCCCATCTC TGTACTCCACCTACTGCCAGGCCTGCTCTGCTGCTGAAGAGAAGCCAGAAGATGCAGCCCTGGGAGTGAGGGCAGAACCCAACTCTGCTG AGGAGCCCCTGGGACAGCTCACAGCTGCACTGGGAGAGCTGAGAGCCTCCATGACAGACCCCAGCCAGCGTGATGTTATATCGGCACAGG TGGCAGTGATTTCTGAAAGACTGAGGGCTGTCCTGGGCCACAATGAGGATGACAGCAGCGTTGAGATATCAAAGATTCAGCTCAGCATCA ACACGCCGAGACTGGAGCCACGGGAACACATGGCTGTGGACCTCCTGCTGACGTCTTTCTGTCAGAACCTGATGGCTGCCTCCAGTGTCG CTCCCCCGGAGAGGCAGGGTCCCTGGGCTGCCCTCTTCGTGAGGACCATGTGTGGACGTGTGCTCCCTGCAGTGCTCACCCGGCTCTGCC AGCTGCTCCGTCACCAGGGCCCGAGCCTGAGTGCCCCACATGTGCTGGGGTTGGCTGCCCTGGCCGTGCACCTGGGTGAGTCCAGGTCTG CGCTCCCAGAGGTGGATGTGGGTCCTCCTGCACCTGGTGCTGGCCTTCCTGTCCCTGCGCTCTTTGACAGCCTCCTGACCTGTAGGACGA GGGATTCCTTGTTCTTCTGCCTGAAATTTTGTACAGCAGCAATTTCTTACTCTCTCTGCAAGTTTTCTTCCCAGTCACGAGATACTTTGT GCAGCTGCTTATCTCCAGGCCTTATTAAAAAGTTTCAGTTCCTCATGTTCAGATTGTTCTCAGAGGCCCGACAGCCTCTTTCTGAGGAGG ACGTAGCCAGCCTTTCCTGGAGACCCTTGCACCTTCCTTCTGCAGACTGGCAGAGAGCTGCCCTCTCTCTCTGGACACACAGAACCTTCC GAGAGGTGTTGAAAGAGGAAGATGTTCACTTAACTTACCAAGACTGGTTACACCTGGAGCTGGAAATTCAACCTGAAGCTGATGCTCTTT CAGATACTGAACGGCAGGACTTCCACCAGTGGGCGATCCATGAGCACTTTCTCCCTGAGTCCTCGGCTTCAGGGGGCTGTGACGGAGACC TGCAGGCTGCGTGTACCATTCTTGTCAACGCACTGATGGATTTCCACCAAAGCTCAAGGAGTTATGACCACTCAGAAAATTCTGATTTGG TCTTTGGTGGCCGCACAGGAAATGAGGATATTATTTCCAGATTGCAGGAGATGGTAGCTGACCTGGAGCTGCAGCAAGACCTCATAGTGC CTCTCGGCCACACCCCTTCCCAGGAGCACTTCCTCTTTGAGATTTTCCGCAGACGGCTCCAGGCTCTGACAAGCGGGTGGAGCGTGGCTG CCAGCCTTCAGAGACAGAGGGAGCTGCTAATGTACAAACGGATCCTCCTCCGCCTGCCTTCGTCTGTCCTCTGCGGCAGCAGCTTCCAGG CAGAACAGCCCATCACTGCCAGATGCGAGCAGTTCTTCCACTTGGTCAACTCTGAGATGAGAAACTTCTGCTCCCACGGAGGTGCCCTGA CACAGGACATCACTGCCCACTTCTTCAGGGGCCTCCTGAACGCCTGTCTGCGGAGCAGAGACCCCTCCCTGATGGTCGACTTCATACTGG CCAAGTGCCAGACGAAATGCCCCTTAATTTTGACCTCTGCTCTGGTGTGGTGGCCGAGCCTGGAGCCTGTGCTGCTCTGCCGGTGGAGGA GACACTGCCAGAGCCCGCTGCCCCGGGAACTGCAGAAGCTACAAGAAGGCCGGCAGTTTGCCAGCGATTTCCTCTCCCCTGAGGCTGCCT CCCCAGCACCCAACCCGGACTGGCTCTCAGCTGCTGCACTGCACTTTGCGATTCAACAAGTCAGGGAAGAAAACATCAGGAAGCAGCTAA AGAAGCTGGACTGCGAGAGAGAGGAGCTATTGGTTTTCCTTTTCTTCTTCTCCTTGATGGGCCTGCTGTCGTCACATCTGACCTCAAATA GCACCACAGACCTGCCAAAGGCTTTCCACGTTTGTGCAGCAATCCTCGAGTGTTTAGAGAAGAGGAAGATATCCTGGCTGGCACTCTTTC AGTTGACAGAGAGTGACCTCAGGCTGGGGCGGCTCCTCCTCCGTGTGGCCCCGGATCAGCACACCAGGCTGCTGCCTTTCGCTTTTTACA GTCTTCTCTCCTACTTCCATGAAGACGCGGCCATCAGGGAAGAGGCCTTCCTGCATGTTGCTGTGGACATGTACTTGAAGCTGGTCCAGC TCTTCGTGGCTGGGGATACAAGCACAGTTTCACCTCCAGCTGGCAGGAGCCTGGAGCTCAAGGGTCAGGCAGGGCAACCCCGTGGAACTG ATAACAAAAGCTCGTCTTTTTCTGCTGCAGTTAATACCTCGGTGCCCGAAAAAGAGCTTCTCACACGTGGCAGAGCTGCTGGCTGATCGT GGGGACTGCGACCCAGAGGTGAGCGCCGCCCTCCAGAGCAGACAGCAGGCTGCCCCTGACGCTGACCTGTCCCAGGAGCCTCATCTCTTC TGACGGGACCTGCCACTGCACACCAGCCCAGCTCCCGTGTAAATAATTTATTACAAGCATAACATGGAGCTCTTGTTGCACTAAAAAGTG GATTACAAATCTCCTCGACTGCTTTAGTGGGGAAAGGAATCAATTATTTATGAACTGTCCGGCCCCGAGTCACTCAGCGTTTGCGGGAAA >16524_16524_8_CHMP1A-FANCA_CHMP1A_chr16_89723990_ENST00000253475_FANCA_chr16_89851372_ENST00000568369_length(amino acids)=989AA_BP=18 MASLLPLRVLLLSLWPWTASFGSTRGYHGCSKKALVFLFTFLSELVPFESPRYLQVHILHPPLVPGKYRSLLTDYISLAKTRLADLKVSI ENMGLYEDLSSAGDITEPHSQALQDVEKAIMVFEHTGNIPVTVMEASIFRRPYYVSHFLPALLTPRVLPKVPDSRVAFIESLKRADKIPP SLYSTYCQACSAAEEKPEDAALGVRAEPNSAEEPLGQLTAALGELRASMTDPSQRDVISAQVAVISERLRAVLGHNEDDSSVEISKIQLS INTPRLEPREHMAVDLLLTSFCQNLMAASSVAPPERQGPWAALFVRTMCGRVLPAVLTRLCQLLRHQGPSLSAPHVLGLAALAVHLGESR SALPEVDVGPPAPGAGLPVPALFDSLLTCRTRDSLFFCLKFCTAAISYSLCKFSSQSRDTLCSCLSPGLIKKFQFLMFRLFSEARQPLSE EDVASLSWRPLHLPSADWQRAALSLWTHRTFREVLKEEDVHLTYQDWLHLELEIQPEADALSDTERQDFHQWAIHEHFLPESSASGGCDG DLQAACTILVNALMDFHQSSRSYDHSENSDLVFGGRTGNEDIISRLQEMVADLELQQDLIVPLGHTPSQEHFLFEIFRRRLQALTSGWSV AASLQRQRELLMYKRILLRLPSSVLCGSSFQAEQPITARCEQFFHLVNSEMRNFCSHGGALTQDITAHFFRGLLNACLRSRDPSLMVDFI LAKCQTKCPLILTSALVWWPSLEPVLLCRWRRHCQSPLPRELQKLQEGRQFASDFLSPEAASPAPNPDWLSAAALHFAIQQVREENIRKQ LKKLDCEREELLVFLFFFSLMGLLSSHLTSNSTTDLPKAFHVCAAILECLEKRKISWLALFQLTESDLRLGRLLLRVAPDQHTRLLPFAF -------------------------------------------------------------- >16524_16524_9_CHMP1A-FANCA_CHMP1A_chr16_89723990_ENST00000397901_FANCA_chr16_89851372_ENST00000389301_length(transcript)=4325nt_BP=264nt AGCGACTCACAAAAGGTCCTCGCGCCAGCGGCGTGCGTCACCATGGCGACCGCGCGCCGCGCAGCCGCGCCCCGCCCCTCTGGCGGGACC GGCCACCATCCTCTCGCGAGAGCATCCCGTGCGACCGGAAGTGGGGCGGCGACCCCGGAAGTCCCCGCCGGGTGCAGCTTGGTCGGTTCG ATCGCCGCCGGGACCTGACACCGCCCGGAGTTGGCGTCCCTTCTCCCTCTCCGAGTGCTGCTCCTGTCATTGTGGCCATGGACGGCCTCC TTTGGGAGCACACGAGGCTACCATGGCTGCAGCAAGAAGGCCCTGGTCTTCCTGTTTACGTTCTTGTCAGAACTCGTGCCTTTTGAGTCT CCCCGGTACCTGCAGGTGCACATTCTCCACCCACCCCTGGTTCCCGGCAAGTACCGCTCCCTCCTCACAGACTACATCTCATTGGCCAAG ACACGGCTGGCCGACCTCAAGGTTTCTATAGAAAACATGGGACTCTACGAGGATTTGTCATCAGCTGGGGACATTACTGAGCCCCACAGC CAAGCTCTTCAGGATGTTGAAAAGGCCATCATGGTGTTTGAGCATACGGGGAACATCCCAGTCACCGTCATGGAGGCCAGCATATTCAGG AGGCCTTACTACGTGTCCCACTTCCTCCCCGCCCTGCTCACACCTCGAGTGCTCCCCAAAGTCCCTGACTCCCGTGTGGCGTTTATAGAG TCTCTGAAGAGAGCAGATAAAATCCCCCCATCTCTGTACTCCACCTACTGCCAGGCCTGCTCTGCTGCTGAAGAGAAGCCAGAAGATGCA GCCCTGGGAGTGAGGGCAGAACCCAACTCTGCTGAGGAGCCCCTGGGACAGCTCACAGCTGCACTGGGAGAGCTGAGAGCCTCCATGACA GACCCCAGCCAGCGTGATGTTATATCGGCACAGGTGGCAGTGATTTCTGAAAGACTGAGGGCTGTCCTGGGCCACAATGAGGATGACAGC AGCGTTGAGATATCAAAGATTCAGCTCAGCATCAACACGCCGAGACTGGAGCCACGGGAACACATGGCTGTGGACCTCCTGCTGACGTCT TTCTGTCAGAACCTGATGGCTGCCTCCAGTGTCGCTCCCCCGGAGAGGCAGGGTCCCTGGGCTGCCCTCTTCGTGAGGACCATGTGTGGA CGTGTGCTCCCTGCAGTGCTCACCCGGCTCTGCCAGCTGCTCCGTCACCAGGGCCCGAGCCTGAGTGCCCCACATGTGCTGGGGTTGGCT GCCCTGGCCGTGCACCTGGGTGAGTCCAGGTCTGCGCTCCCAGAGGTGGATGTGGGTCCTCCTGCACCTGGTGCTGGCCTTCCTGTCCCT GCGCTCTTTGACAGCCTCCTGACCTGTAGGACGAGGGATTCCTTGTTCTTCTGCCTGAAATTTTGTACAGCAGCAATTTCTTACTCTCTC TGCAAGTTTTCTTCCCAGTCACGAGATACTTTGTGCAGCTGCTTATCTCCAGGCCTTATTAAAAAGTTTCAGTTCCTCATGTTCAGATTG TTCTCAGAGGCCCGACAGCCTCTTTCTGAGGAGGACGTAGCCAGCCTTTCCTGGAGACCCTTGCACCTTCCTTCTGCAGACTGGCAGAGA GCTGCCCTCTCTCTCTGGACACACAGAACCTTCCGAGAGGTGTTGAAAGAGGAAGATGTTCACTTAACTTACCAAGACTGGTTACACCTG GAGCTGGAAATTCAACCTGAAGCTGATGCTCTTTCAGATACTGAACGGCAGGACTTCCACCAGTGGGCGATCCATGAGCACTTTCTCCCT GAGTCCTCGGCTTCAGGGGGCTGTGACGGAGACCTGCAGGCTGCGTGTACCATTCTTGTCAACGCACTGATGGATTTCCACCAAAGCTCA AGGAGTTATGACCACTCAGAAAATTCTGATTTGGTCTTTGGTGGCCGCACAGGAAATGAGGATATTATTTCCAGATTGCAGGAGATGGTA GCTGACCTGGAGCTGCAGCAAGACCTCATAGTGCCTCTCGGCCACACCCCTTCCCAGGAGCACTTCCTCTTTGAGATTTTCCGCAGACGG CTCCAGGCTCTGACAAGCGGGTGGAGCGTGGCTGCCAGCCTTCAGAGACAGAGGGAGCTGCTAATGTACAAACGGATCCTCCTCCGCCTG CCTTCGTCTGTCCTCTGCGGCAGCAGCTTCCAGGCAGAACAGCCCATCACTGCCAGATGCGAGCAGTTCTTCCACTTGGTCAACTCTGAG ATGAGAAACTTCTGCTCCCACGGAGGTGCCCTGACACAGGACATCACTGCCCACTTCTTCAGGGGCCTCCTGAACGCCTGTCTGCGGAGC AGAGACCCCTCCCTGATGGTCGACTTCATACTGGCCAAGTGCCAGACGAAATGCCCCTTAATTTTGACCTCTGCTCTGGTGTGGTGGCCG AGCCTGGAGCCTGTGCTGCTCTGCCGGTGGAGGAGACACTGCCAGAGCCCGCTGCCCCGGGAACTGCAGAAGCTACAAGAAGGCCGGCAG TTTGCCAGCGATTTCCTCTCCCCTGAGGCTGCCTCCCCAGCACCCAACCCGGACTGGCTCTCAGCTGCTGCACTGCACTTTGCGATTCAA CAAGTCAGGGAAGAAAACATCAGGAAGCAGCTAAAGAAGCTGGACTGCGAGAGAGAGGAGCTATTGGTTTTCCTTTTCTTCTTCTCCTTG ATGGGCCTGCTGTCGTCACATCTGACCTCAAATAGCACCACAGACCTGCCAAAGGCTTTCCACGTTTGTGCAGCAATCCTCGAGTGTTTA GAGAAGAGGAAGATATCCTGGCTGGCACTCTTTCAGTTGACAGAGAGTGACCTCAGGCTGGGGCGGCTCCTCCTCCGTGTGGCCCCGGAT CAGCACACCAGGCTGCTGCCTTTCGCTTTTTACAGTCTTCTCTCCTACTTCCATGAAGACGCGGCCATCAGGGAAGAGGCCTTCCTGCAT GTTGCTGTGGACATGTACTTGAAGCTGGTCCAGCTCTTCGTGGCTGGGGATACAAGCACAGTTTCACCTCCAGCTGGCAGGAGCCTGGAG CTCAAGGGTCAGGGCAACCCCGTGGAACTGATAACAAAAGCTCGTCTTTTTCTGCTGCAGTTAATACCTCGGTGCCCGAAAAAGAGCTTC TCACACGTGGCAGAGCTGCTGGCTGATCGTGGGGACTGCGACCCAGAGGTGAGCGCCGCCCTCCAGAGCAGACAGCAGGCTGCCCCTGAC GCTGACCTGTCCCAGGAGCCTCATCTCTTCTGACGGGACCTGCCACTGCACACCAGCCCAGCTCCCGTGTAAATAATTTATTACAAGCAT AACATGGAGCTCTTGTTGCACTAAAAAGTGGATTACAAATCTCCTCGACTGCTTTAGTGGGGAAAGGAATCAATTATTTATGAACTGTCC GGCCCCGAGTCACTCAGCGTTTGCGGGAAAATAAACCACTGGTCCCAGAGCAGAGGAAGGCTACTTGAGCCGGACACCAAGCCCGCCTCC AGCACCAAGGGCGGGCAGCACCCTCCGACCCTCCCATGCGGGTGCACACGAAGGGTGAGGCTGACACAGCCACTGCGGAGTCCAGGCTGC TAGAGGTGCTCATCCTCACTGCCGTCCTCAGGTGGGTTCGGGCTTCACCGCCTGGCCCTCTGTGGTCACAGAGGGGCTCGGTGGCCCAGG TGGTGGTTCCGCCTCCAGGGGCAGGGCCTTGTCCTGGGTCTGTGTCAGCGGGTGCACCATGGACATGTGTACATTGAGGTTGTGGGCCTT CTCAAACCGCCGGCCACACTGGTCACAGGCAAAGTCCAGCTCAGTCTCAGCCTTGTGTTTGGTCATGTGGTACTTGAGGGATGCCCGCTG CCTGCACTGGAACCCACAGACCTCACACCTGGGGGACAGAGGCAGATAAGAAGGTGCGAGGGCCACAGCCCTGGGAGGGGGTCCTGACTC ACACTTACTGCAAAGGCTTGGCTCCCGAATGTCGCATTTGGTGGACGAGAAGGTGCTTCCGCTGCTTGAAGGTTTGTCCACATTCGTCAC AGATATAGTTCCGCACCTCTGAGAGGGGAGAGTCCAGTGAGTCCAGGCCCCTGATGCTCCAACCTCCCGGGGGGACGACGATGACAATGT GAAACCATCACAGCTGGGAAGACATTTCTGCACATGGTTCACCATGCAGTGGGCCCAAGCAAGGGGCCTATGAGGGCCTCGTTTATTAAG ATCTTTAAACTGCTTTATACACTGTCACGTGGCTTCATCAGCTGTGTGCATTTCAGGATGGTTTTTAAAGAAACCTCAGAAAGCTATTTC >16524_16524_9_CHMP1A-FANCA_CHMP1A_chr16_89723990_ENST00000397901_FANCA_chr16_89851372_ENST00000389301_length(amino acids)=1020AA_BP=18 MASLLPLRVLLLSLWPWTASFGSTRGYHGCSKKALVFLFTFLSELVPFESPRYLQVHILHPPLVPGKYRSLLTDYISLAKTRLADLKVSI ENMGLYEDLSSAGDITEPHSQALQDVEKAIMVFEHTGNIPVTVMEASIFRRPYYVSHFLPALLTPRVLPKVPDSRVAFIESLKRADKIPP SLYSTYCQACSAAEEKPEDAALGVRAEPNSAEEPLGQLTAALGELRASMTDPSQRDVISAQVAVISERLRAVLGHNEDDSSVEISKIQLS INTPRLEPREHMAVDLLLTSFCQNLMAASSVAPPERQGPWAALFVRTMCGRVLPAVLTRLCQLLRHQGPSLSAPHVLGLAALAVHLGESR SALPEVDVGPPAPGAGLPVPALFDSLLTCRTRDSLFFCLKFCTAAISYSLCKFSSQSRDTLCSCLSPGLIKKFQFLMFRLFSEARQPLSE EDVASLSWRPLHLPSADWQRAALSLWTHRTFREVLKEEDVHLTYQDWLHLELEIQPEADALSDTERQDFHQWAIHEHFLPESSASGGCDG DLQAACTILVNALMDFHQSSRSYDHSENSDLVFGGRTGNEDIISRLQEMVADLELQQDLIVPLGHTPSQEHFLFEIFRRRLQALTSGWSV AASLQRQRELLMYKRILLRLPSSVLCGSSFQAEQPITARCEQFFHLVNSEMRNFCSHGGALTQDITAHFFRGLLNACLRSRDPSLMVDFI LAKCQTKCPLILTSALVWWPSLEPVLLCRWRRHCQSPLPRELQKLQEGRQFASDFLSPEAASPAPNPDWLSAAALHFAIQQVREENIRKQ LKKLDCEREELLVFLFFFSLMGLLSSHLTSNSTTDLPKAFHVCAAILECLEKRKISWLALFQLTESDLRLGRLLLRVAPDQHTRLLPFAF YSLLSYFHEDAAIREEAFLHVAVDMYLKLVQLFVAGDTSTVSPPAGRSLELKGQGNPVELITKARLFLLQLIPRCPKKSFSHVAELLADR -------------------------------------------------------------- >16524_16524_10_CHMP1A-FANCA_CHMP1A_chr16_89723990_ENST00000397901_FANCA_chr16_89851372_ENST00000568369_length(transcript)=3475nt_BP=264nt AGCGACTCACAAAAGGTCCTCGCGCCAGCGGCGTGCGTCACCATGGCGACCGCGCGCCGCGCAGCCGCGCCCCGCCCCTCTGGCGGGACC GGCCACCATCCTCTCGCGAGAGCATCCCGTGCGACCGGAAGTGGGGCGGCGACCCCGGAAGTCCCCGCCGGGTGCAGCTTGGTCGGTTCG ATCGCCGCCGGGACCTGACACCGCCCGGAGTTGGCGTCCCTTCTCCCTCTCCGAGTGCTGCTCCTGTCATTGTGGCCATGGACGGCCTCC TTTGGGAGCACACGAGGCTACCATGGCTGCAGCAAGAAGGCCCTGGTCTTCCTGTTTACGTTCTTGTCAGAACTCGTGCCTTTTGAGTCT CCCCGGTACCTGCAGGTGCACATTCTCCACCCACCCCTGGTTCCCGGCAAGTACCGCTCCCTCCTCACAGACTACATCTCATTGGCCAAG ACACGGCTGGCCGACCTCAAGGTTTCTATAGAAAACATGGGACTCTACGAGGATTTGTCATCAGCTGGGGACATTACTGAGCCCCACAGC CAAGCTCTTCAGGATGTTGAAAAGGCCATCATGGTGTTTGAGCATACGGGGAACATCCCAGTCACCGTCATGGAGGCCAGCATATTCAGG AGGCCTTACTACGTGTCCCACTTCCTCCCCGCCCTGCTCACACCTCGAGTGCTCCCCAAAGTCCCTGACTCCCGTGTGGCGTTTATAGAG TCTCTGAAGAGAGCAGATAAAATCCCCCCATCTCTGTACTCCACCTACTGCCAGGCCTGCTCTGCTGCTGAAGAGAAGCCAGAAGATGCA GCCCTGGGAGTGAGGGCAGAACCCAACTCTGCTGAGGAGCCCCTGGGACAGCTCACAGCTGCACTGGGAGAGCTGAGAGCCTCCATGACA GACCCCAGCCAGCGTGATGTTATATCGGCACAGGTGGCAGTGATTTCTGAAAGACTGAGGGCTGTCCTGGGCCACAATGAGGATGACAGC AGCGTTGAGATATCAAAGATTCAGCTCAGCATCAACACGCCGAGACTGGAGCCACGGGAACACATGGCTGTGGACCTCCTGCTGACGTCT TTCTGTCAGAACCTGATGGCTGCCTCCAGTGTCGCTCCCCCGGAGAGGCAGGGTCCCTGGGCTGCCCTCTTCGTGAGGACCATGTGTGGA CGTGTGCTCCCTGCAGTGCTCACCCGGCTCTGCCAGCTGCTCCGTCACCAGGGCCCGAGCCTGAGTGCCCCACATGTGCTGGGGTTGGCT GCCCTGGCCGTGCACCTGGGTGAGTCCAGGTCTGCGCTCCCAGAGGTGGATGTGGGTCCTCCTGCACCTGGTGCTGGCCTTCCTGTCCCT GCGCTCTTTGACAGCCTCCTGACCTGTAGGACGAGGGATTCCTTGTTCTTCTGCCTGAAATTTTGTACAGCAGCAATTTCTTACTCTCTC TGCAAGTTTTCTTCCCAGTCACGAGATACTTTGTGCAGCTGCTTATCTCCAGGCCTTATTAAAAAGTTTCAGTTCCTCATGTTCAGATTG TTCTCAGAGGCCCGACAGCCTCTTTCTGAGGAGGACGTAGCCAGCCTTTCCTGGAGACCCTTGCACCTTCCTTCTGCAGACTGGCAGAGA GCTGCCCTCTCTCTCTGGACACACAGAACCTTCCGAGAGGTGTTGAAAGAGGAAGATGTTCACTTAACTTACCAAGACTGGTTACACCTG GAGCTGGAAATTCAACCTGAAGCTGATGCTCTTTCAGATACTGAACGGCAGGACTTCCACCAGTGGGCGATCCATGAGCACTTTCTCCCT GAGTCCTCGGCTTCAGGGGGCTGTGACGGAGACCTGCAGGCTGCGTGTACCATTCTTGTCAACGCACTGATGGATTTCCACCAAAGCTCA AGGAGTTATGACCACTCAGAAAATTCTGATTTGGTCTTTGGTGGCCGCACAGGAAATGAGGATATTATTTCCAGATTGCAGGAGATGGTA GCTGACCTGGAGCTGCAGCAAGACCTCATAGTGCCTCTCGGCCACACCCCTTCCCAGGAGCACTTCCTCTTTGAGATTTTCCGCAGACGG CTCCAGGCTCTGACAAGCGGGTGGAGCGTGGCTGCCAGCCTTCAGAGACAGAGGGAGCTGCTAATGTACAAACGGATCCTCCTCCGCCTG CCTTCGTCTGTCCTCTGCGGCAGCAGCTTCCAGGCAGAACAGCCCATCACTGCCAGATGCGAGCAGTTCTTCCACTTGGTCAACTCTGAG ATGAGAAACTTCTGCTCCCACGGAGGTGCCCTGACACAGGACATCACTGCCCACTTCTTCAGGGGCCTCCTGAACGCCTGTCTGCGGAGC AGAGACCCCTCCCTGATGGTCGACTTCATACTGGCCAAGTGCCAGACGAAATGCCCCTTAATTTTGACCTCTGCTCTGGTGTGGTGGCCG AGCCTGGAGCCTGTGCTGCTCTGCCGGTGGAGGAGACACTGCCAGAGCCCGCTGCCCCGGGAACTGCAGAAGCTACAAGAAGGCCGGCAG TTTGCCAGCGATTTCCTCTCCCCTGAGGCTGCCTCCCCAGCACCCAACCCGGACTGGCTCTCAGCTGCTGCACTGCACTTTGCGATTCAA CAAGTCAGGGAAGAAAACATCAGGAAGCAGCTAAAGAAGCTGGACTGCGAGAGAGAGGAGCTATTGGTTTTCCTTTTCTTCTTCTCCTTG ATGGGCCTGCTGTCGTCACATCTGACCTCAAATAGCACCACAGACCTGCCAAAGGCTTTCCACGTTTGTGCAGCAATCCTCGAGTGTTTA GAGAAGAGGAAGATATCCTGGCTGGCACTCTTTCAGTTGACAGAGAGTGACCTCAGGCTGGGGCGGCTCCTCCTCCGTGTGGCCCCGGAT CAGCACACCAGGCTGCTGCCTTTCGCTTTTTACAGTCTTCTCTCCTACTTCCATGAAGACGCGGCCATCAGGGAAGAGGCCTTCCTGCAT GTTGCTGTGGACATGTACTTGAAGCTGGTCCAGCTCTTCGTGGCTGGGGATACAAGCACAGTTTCACCTCCAGCTGGCAGGAGCCTGGAG CTCAAGGGTCAGGCAGGGCAACCCCGTGGAACTGATAACAAAAGCTCGTCTTTTTCTGCTGCAGTTAATACCTCGGTGCCCGAAAAAGAG CTTCTCACACGTGGCAGAGCTGCTGGCTGATCGTGGGGACTGCGACCCAGAGGTGAGCGCCGCCCTCCAGAGCAGACAGCAGGCTGCCCC TGACGCTGACCTGTCCCAGGAGCCTCATCTCTTCTGACGGGACCTGCCACTGCACACCAGCCCAGCTCCCGTGTAAATAATTTATTACAA GCATAACATGGAGCTCTTGTTGCACTAAAAAGTGGATTACAAATCTCCTCGACTGCTTTAGTGGGGAAAGGAATCAATTATTTATGAACT >16524_16524_10_CHMP1A-FANCA_CHMP1A_chr16_89723990_ENST00000397901_FANCA_chr16_89851372_ENST00000568369_length(amino acids)=989AA_BP=18 MASLLPLRVLLLSLWPWTASFGSTRGYHGCSKKALVFLFTFLSELVPFESPRYLQVHILHPPLVPGKYRSLLTDYISLAKTRLADLKVSI ENMGLYEDLSSAGDITEPHSQALQDVEKAIMVFEHTGNIPVTVMEASIFRRPYYVSHFLPALLTPRVLPKVPDSRVAFIESLKRADKIPP SLYSTYCQACSAAEEKPEDAALGVRAEPNSAEEPLGQLTAALGELRASMTDPSQRDVISAQVAVISERLRAVLGHNEDDSSVEISKIQLS INTPRLEPREHMAVDLLLTSFCQNLMAASSVAPPERQGPWAALFVRTMCGRVLPAVLTRLCQLLRHQGPSLSAPHVLGLAALAVHLGESR SALPEVDVGPPAPGAGLPVPALFDSLLTCRTRDSLFFCLKFCTAAISYSLCKFSSQSRDTLCSCLSPGLIKKFQFLMFRLFSEARQPLSE EDVASLSWRPLHLPSADWQRAALSLWTHRTFREVLKEEDVHLTYQDWLHLELEIQPEADALSDTERQDFHQWAIHEHFLPESSASGGCDG DLQAACTILVNALMDFHQSSRSYDHSENSDLVFGGRTGNEDIISRLQEMVADLELQQDLIVPLGHTPSQEHFLFEIFRRRLQALTSGWSV AASLQRQRELLMYKRILLRLPSSVLCGSSFQAEQPITARCEQFFHLVNSEMRNFCSHGGALTQDITAHFFRGLLNACLRSRDPSLMVDFI LAKCQTKCPLILTSALVWWPSLEPVLLCRWRRHCQSPLPRELQKLQEGRQFASDFLSPEAASPAPNPDWLSAAALHFAIQQVREENIRKQ LKKLDCEREELLVFLFFFSLMGLLSSHLTSNSTTDLPKAFHVCAAILECLEKRKISWLALFQLTESDLRLGRLLLRVAPDQHTRLLPFAF -------------------------------------------------------------- >16524_16524_11_CHMP1A-FANCA_CHMP1A_chr16_89723990_ENST00000550102_FANCA_chr16_89851372_ENST00000389301_length(transcript)=4130nt_BP=69nt TGACACCGCCCGGAGTTGGCGTCCCTTCTCCCTCTCCGAGTGCTGCTCCTGTCATTGTGGCCATGGACGGCCTCCTTTGGGAGCACACGA GGCTACCATGGCTGCAGCAAGAAGGCCCTGGTCTTCCTGTTTACGTTCTTGTCAGAACTCGTGCCTTTTGAGTCTCCCCGGTACCTGCAG GTGCACATTCTCCACCCACCCCTGGTTCCCGGCAAGTACCGCTCCCTCCTCACAGACTACATCTCATTGGCCAAGACACGGCTGGCCGAC CTCAAGGTTTCTATAGAAAACATGGGACTCTACGAGGATTTGTCATCAGCTGGGGACATTACTGAGCCCCACAGCCAAGCTCTTCAGGAT GTTGAAAAGGCCATCATGGTGTTTGAGCATACGGGGAACATCCCAGTCACCGTCATGGAGGCCAGCATATTCAGGAGGCCTTACTACGTG TCCCACTTCCTCCCCGCCCTGCTCACACCTCGAGTGCTCCCCAAAGTCCCTGACTCCCGTGTGGCGTTTATAGAGTCTCTGAAGAGAGCA GATAAAATCCCCCCATCTCTGTACTCCACCTACTGCCAGGCCTGCTCTGCTGCTGAAGAGAAGCCAGAAGATGCAGCCCTGGGAGTGAGG GCAGAACCCAACTCTGCTGAGGAGCCCCTGGGACAGCTCACAGCTGCACTGGGAGAGCTGAGAGCCTCCATGACAGACCCCAGCCAGCGT GATGTTATATCGGCACAGGTGGCAGTGATTTCTGAAAGACTGAGGGCTGTCCTGGGCCACAATGAGGATGACAGCAGCGTTGAGATATCA AAGATTCAGCTCAGCATCAACACGCCGAGACTGGAGCCACGGGAACACATGGCTGTGGACCTCCTGCTGACGTCTTTCTGTCAGAACCTG ATGGCTGCCTCCAGTGTCGCTCCCCCGGAGAGGCAGGGTCCCTGGGCTGCCCTCTTCGTGAGGACCATGTGTGGACGTGTGCTCCCTGCA GTGCTCACCCGGCTCTGCCAGCTGCTCCGTCACCAGGGCCCGAGCCTGAGTGCCCCACATGTGCTGGGGTTGGCTGCCCTGGCCGTGCAC CTGGGTGAGTCCAGGTCTGCGCTCCCAGAGGTGGATGTGGGTCCTCCTGCACCTGGTGCTGGCCTTCCTGTCCCTGCGCTCTTTGACAGC CTCCTGACCTGTAGGACGAGGGATTCCTTGTTCTTCTGCCTGAAATTTTGTACAGCAGCAATTTCTTACTCTCTCTGCAAGTTTTCTTCC CAGTCACGAGATACTTTGTGCAGCTGCTTATCTCCAGGCCTTATTAAAAAGTTTCAGTTCCTCATGTTCAGATTGTTCTCAGAGGCCCGA CAGCCTCTTTCTGAGGAGGACGTAGCCAGCCTTTCCTGGAGACCCTTGCACCTTCCTTCTGCAGACTGGCAGAGAGCTGCCCTCTCTCTC TGGACACACAGAACCTTCCGAGAGGTGTTGAAAGAGGAAGATGTTCACTTAACTTACCAAGACTGGTTACACCTGGAGCTGGAAATTCAA CCTGAAGCTGATGCTCTTTCAGATACTGAACGGCAGGACTTCCACCAGTGGGCGATCCATGAGCACTTTCTCCCTGAGTCCTCGGCTTCA GGGGGCTGTGACGGAGACCTGCAGGCTGCGTGTACCATTCTTGTCAACGCACTGATGGATTTCCACCAAAGCTCAAGGAGTTATGACCAC TCAGAAAATTCTGATTTGGTCTTTGGTGGCCGCACAGGAAATGAGGATATTATTTCCAGATTGCAGGAGATGGTAGCTGACCTGGAGCTG CAGCAAGACCTCATAGTGCCTCTCGGCCACACCCCTTCCCAGGAGCACTTCCTCTTTGAGATTTTCCGCAGACGGCTCCAGGCTCTGACA AGCGGGTGGAGCGTGGCTGCCAGCCTTCAGAGACAGAGGGAGCTGCTAATGTACAAACGGATCCTCCTCCGCCTGCCTTCGTCTGTCCTC TGCGGCAGCAGCTTCCAGGCAGAACAGCCCATCACTGCCAGATGCGAGCAGTTCTTCCACTTGGTCAACTCTGAGATGAGAAACTTCTGC TCCCACGGAGGTGCCCTGACACAGGACATCACTGCCCACTTCTTCAGGGGCCTCCTGAACGCCTGTCTGCGGAGCAGAGACCCCTCCCTG ATGGTCGACTTCATACTGGCCAAGTGCCAGACGAAATGCCCCTTAATTTTGACCTCTGCTCTGGTGTGGTGGCCGAGCCTGGAGCCTGTG CTGCTCTGCCGGTGGAGGAGACACTGCCAGAGCCCGCTGCCCCGGGAACTGCAGAAGCTACAAGAAGGCCGGCAGTTTGCCAGCGATTTC CTCTCCCCTGAGGCTGCCTCCCCAGCACCCAACCCGGACTGGCTCTCAGCTGCTGCACTGCACTTTGCGATTCAACAAGTCAGGGAAGAA AACATCAGGAAGCAGCTAAAGAAGCTGGACTGCGAGAGAGAGGAGCTATTGGTTTTCCTTTTCTTCTTCTCCTTGATGGGCCTGCTGTCG TCACATCTGACCTCAAATAGCACCACAGACCTGCCAAAGGCTTTCCACGTTTGTGCAGCAATCCTCGAGTGTTTAGAGAAGAGGAAGATA TCCTGGCTGGCACTCTTTCAGTTGACAGAGAGTGACCTCAGGCTGGGGCGGCTCCTCCTCCGTGTGGCCCCGGATCAGCACACCAGGCTG CTGCCTTTCGCTTTTTACAGTCTTCTCTCCTACTTCCATGAAGACGCGGCCATCAGGGAAGAGGCCTTCCTGCATGTTGCTGTGGACATG TACTTGAAGCTGGTCCAGCTCTTCGTGGCTGGGGATACAAGCACAGTTTCACCTCCAGCTGGCAGGAGCCTGGAGCTCAAGGGTCAGGGC AACCCCGTGGAACTGATAACAAAAGCTCGTCTTTTTCTGCTGCAGTTAATACCTCGGTGCCCGAAAAAGAGCTTCTCACACGTGGCAGAG CTGCTGGCTGATCGTGGGGACTGCGACCCAGAGGTGAGCGCCGCCCTCCAGAGCAGACAGCAGGCTGCCCCTGACGCTGACCTGTCCCAG GAGCCTCATCTCTTCTGACGGGACCTGCCACTGCACACCAGCCCAGCTCCCGTGTAAATAATTTATTACAAGCATAACATGGAGCTCTTG TTGCACTAAAAAGTGGATTACAAATCTCCTCGACTGCTTTAGTGGGGAAAGGAATCAATTATTTATGAACTGTCCGGCCCCGAGTCACTC AGCGTTTGCGGGAAAATAAACCACTGGTCCCAGAGCAGAGGAAGGCTACTTGAGCCGGACACCAAGCCCGCCTCCAGCACCAAGGGCGGG CAGCACCCTCCGACCCTCCCATGCGGGTGCACACGAAGGGTGAGGCTGACACAGCCACTGCGGAGTCCAGGCTGCTAGAGGTGCTCATCC TCACTGCCGTCCTCAGGTGGGTTCGGGCTTCACCGCCTGGCCCTCTGTGGTCACAGAGGGGCTCGGTGGCCCAGGTGGTGGTTCCGCCTC CAGGGGCAGGGCCTTGTCCTGGGTCTGTGTCAGCGGGTGCACCATGGACATGTGTACATTGAGGTTGTGGGCCTTCTCAAACCGCCGGCC ACACTGGTCACAGGCAAAGTCCAGCTCAGTCTCAGCCTTGTGTTTGGTCATGTGGTACTTGAGGGATGCCCGCTGCCTGCACTGGAACCC ACAGACCTCACACCTGGGGGACAGAGGCAGATAAGAAGGTGCGAGGGCCACAGCCCTGGGAGGGGGTCCTGACTCACACTTACTGCAAAG GCTTGGCTCCCGAATGTCGCATTTGGTGGACGAGAAGGTGCTTCCGCTGCTTGAAGGTTTGTCCACATTCGTCACAGATATAGTTCCGCA CCTCTGAGAGGGGAGAGTCCAGTGAGTCCAGGCCCCTGATGCTCCAACCTCCCGGGGGGACGACGATGACAATGTGAAACCATCACAGCT GGGAAGACATTTCTGCACATGGTTCACCATGCAGTGGGCCCAAGCAAGGGGCCTATGAGGGCCTCGTTTATTAAGATCTTTAAACTGCTT >16524_16524_11_CHMP1A-FANCA_CHMP1A_chr16_89723990_ENST00000550102_FANCA_chr16_89851372_ENST00000389301_length(amino acids)=1020AA_BP=18 MASLLPLRVLLLSLWPWTASFGSTRGYHGCSKKALVFLFTFLSELVPFESPRYLQVHILHPPLVPGKYRSLLTDYISLAKTRLADLKVSI ENMGLYEDLSSAGDITEPHSQALQDVEKAIMVFEHTGNIPVTVMEASIFRRPYYVSHFLPALLTPRVLPKVPDSRVAFIESLKRADKIPP SLYSTYCQACSAAEEKPEDAALGVRAEPNSAEEPLGQLTAALGELRASMTDPSQRDVISAQVAVISERLRAVLGHNEDDSSVEISKIQLS INTPRLEPREHMAVDLLLTSFCQNLMAASSVAPPERQGPWAALFVRTMCGRVLPAVLTRLCQLLRHQGPSLSAPHVLGLAALAVHLGESR SALPEVDVGPPAPGAGLPVPALFDSLLTCRTRDSLFFCLKFCTAAISYSLCKFSSQSRDTLCSCLSPGLIKKFQFLMFRLFSEARQPLSE EDVASLSWRPLHLPSADWQRAALSLWTHRTFREVLKEEDVHLTYQDWLHLELEIQPEADALSDTERQDFHQWAIHEHFLPESSASGGCDG DLQAACTILVNALMDFHQSSRSYDHSENSDLVFGGRTGNEDIISRLQEMVADLELQQDLIVPLGHTPSQEHFLFEIFRRRLQALTSGWSV AASLQRQRELLMYKRILLRLPSSVLCGSSFQAEQPITARCEQFFHLVNSEMRNFCSHGGALTQDITAHFFRGLLNACLRSRDPSLMVDFI LAKCQTKCPLILTSALVWWPSLEPVLLCRWRRHCQSPLPRELQKLQEGRQFASDFLSPEAASPAPNPDWLSAAALHFAIQQVREENIRKQ LKKLDCEREELLVFLFFFSLMGLLSSHLTSNSTTDLPKAFHVCAAILECLEKRKISWLALFQLTESDLRLGRLLLRVAPDQHTRLLPFAF YSLLSYFHEDAAIREEAFLHVAVDMYLKLVQLFVAGDTSTVSPPAGRSLELKGQGNPVELITKARLFLLQLIPRCPKKSFSHVAELLADR -------------------------------------------------------------- >16524_16524_12_CHMP1A-FANCA_CHMP1A_chr16_89723990_ENST00000550102_FANCA_chr16_89851372_ENST00000568369_length(transcript)=3280nt_BP=69nt TGACACCGCCCGGAGTTGGCGTCCCTTCTCCCTCTCCGAGTGCTGCTCCTGTCATTGTGGCCATGGACGGCCTCCTTTGGGAGCACACGA GGCTACCATGGCTGCAGCAAGAAGGCCCTGGTCTTCCTGTTTACGTTCTTGTCAGAACTCGTGCCTTTTGAGTCTCCCCGGTACCTGCAG GTGCACATTCTCCACCCACCCCTGGTTCCCGGCAAGTACCGCTCCCTCCTCACAGACTACATCTCATTGGCCAAGACACGGCTGGCCGAC CTCAAGGTTTCTATAGAAAACATGGGACTCTACGAGGATTTGTCATCAGCTGGGGACATTACTGAGCCCCACAGCCAAGCTCTTCAGGAT GTTGAAAAGGCCATCATGGTGTTTGAGCATACGGGGAACATCCCAGTCACCGTCATGGAGGCCAGCATATTCAGGAGGCCTTACTACGTG TCCCACTTCCTCCCCGCCCTGCTCACACCTCGAGTGCTCCCCAAAGTCCCTGACTCCCGTGTGGCGTTTATAGAGTCTCTGAAGAGAGCA GATAAAATCCCCCCATCTCTGTACTCCACCTACTGCCAGGCCTGCTCTGCTGCTGAAGAGAAGCCAGAAGATGCAGCCCTGGGAGTGAGG GCAGAACCCAACTCTGCTGAGGAGCCCCTGGGACAGCTCACAGCTGCACTGGGAGAGCTGAGAGCCTCCATGACAGACCCCAGCCAGCGT GATGTTATATCGGCACAGGTGGCAGTGATTTCTGAAAGACTGAGGGCTGTCCTGGGCCACAATGAGGATGACAGCAGCGTTGAGATATCA AAGATTCAGCTCAGCATCAACACGCCGAGACTGGAGCCACGGGAACACATGGCTGTGGACCTCCTGCTGACGTCTTTCTGTCAGAACCTG ATGGCTGCCTCCAGTGTCGCTCCCCCGGAGAGGCAGGGTCCCTGGGCTGCCCTCTTCGTGAGGACCATGTGTGGACGTGTGCTCCCTGCA GTGCTCACCCGGCTCTGCCAGCTGCTCCGTCACCAGGGCCCGAGCCTGAGTGCCCCACATGTGCTGGGGTTGGCTGCCCTGGCCGTGCAC CTGGGTGAGTCCAGGTCTGCGCTCCCAGAGGTGGATGTGGGTCCTCCTGCACCTGGTGCTGGCCTTCCTGTCCCTGCGCTCTTTGACAGC CTCCTGACCTGTAGGACGAGGGATTCCTTGTTCTTCTGCCTGAAATTTTGTACAGCAGCAATTTCTTACTCTCTCTGCAAGTTTTCTTCC CAGTCACGAGATACTTTGTGCAGCTGCTTATCTCCAGGCCTTATTAAAAAGTTTCAGTTCCTCATGTTCAGATTGTTCTCAGAGGCCCGA CAGCCTCTTTCTGAGGAGGACGTAGCCAGCCTTTCCTGGAGACCCTTGCACCTTCCTTCTGCAGACTGGCAGAGAGCTGCCCTCTCTCTC TGGACACACAGAACCTTCCGAGAGGTGTTGAAAGAGGAAGATGTTCACTTAACTTACCAAGACTGGTTACACCTGGAGCTGGAAATTCAA CCTGAAGCTGATGCTCTTTCAGATACTGAACGGCAGGACTTCCACCAGTGGGCGATCCATGAGCACTTTCTCCCTGAGTCCTCGGCTTCA GGGGGCTGTGACGGAGACCTGCAGGCTGCGTGTACCATTCTTGTCAACGCACTGATGGATTTCCACCAAAGCTCAAGGAGTTATGACCAC TCAGAAAATTCTGATTTGGTCTTTGGTGGCCGCACAGGAAATGAGGATATTATTTCCAGATTGCAGGAGATGGTAGCTGACCTGGAGCTG CAGCAAGACCTCATAGTGCCTCTCGGCCACACCCCTTCCCAGGAGCACTTCCTCTTTGAGATTTTCCGCAGACGGCTCCAGGCTCTGACA AGCGGGTGGAGCGTGGCTGCCAGCCTTCAGAGACAGAGGGAGCTGCTAATGTACAAACGGATCCTCCTCCGCCTGCCTTCGTCTGTCCTC TGCGGCAGCAGCTTCCAGGCAGAACAGCCCATCACTGCCAGATGCGAGCAGTTCTTCCACTTGGTCAACTCTGAGATGAGAAACTTCTGC TCCCACGGAGGTGCCCTGACACAGGACATCACTGCCCACTTCTTCAGGGGCCTCCTGAACGCCTGTCTGCGGAGCAGAGACCCCTCCCTG ATGGTCGACTTCATACTGGCCAAGTGCCAGACGAAATGCCCCTTAATTTTGACCTCTGCTCTGGTGTGGTGGCCGAGCCTGGAGCCTGTG CTGCTCTGCCGGTGGAGGAGACACTGCCAGAGCCCGCTGCCCCGGGAACTGCAGAAGCTACAAGAAGGCCGGCAGTTTGCCAGCGATTTC CTCTCCCCTGAGGCTGCCTCCCCAGCACCCAACCCGGACTGGCTCTCAGCTGCTGCACTGCACTTTGCGATTCAACAAGTCAGGGAAGAA AACATCAGGAAGCAGCTAAAGAAGCTGGACTGCGAGAGAGAGGAGCTATTGGTTTTCCTTTTCTTCTTCTCCTTGATGGGCCTGCTGTCG TCACATCTGACCTCAAATAGCACCACAGACCTGCCAAAGGCTTTCCACGTTTGTGCAGCAATCCTCGAGTGTTTAGAGAAGAGGAAGATA TCCTGGCTGGCACTCTTTCAGTTGACAGAGAGTGACCTCAGGCTGGGGCGGCTCCTCCTCCGTGTGGCCCCGGATCAGCACACCAGGCTG CTGCCTTTCGCTTTTTACAGTCTTCTCTCCTACTTCCATGAAGACGCGGCCATCAGGGAAGAGGCCTTCCTGCATGTTGCTGTGGACATG TACTTGAAGCTGGTCCAGCTCTTCGTGGCTGGGGATACAAGCACAGTTTCACCTCCAGCTGGCAGGAGCCTGGAGCTCAAGGGTCAGGCA GGGCAACCCCGTGGAACTGATAACAAAAGCTCGTCTTTTTCTGCTGCAGTTAATACCTCGGTGCCCGAAAAAGAGCTTCTCACACGTGGC AGAGCTGCTGGCTGATCGTGGGGACTGCGACCCAGAGGTGAGCGCCGCCCTCCAGAGCAGACAGCAGGCTGCCCCTGACGCTGACCTGTC CCAGGAGCCTCATCTCTTCTGACGGGACCTGCCACTGCACACCAGCCCAGCTCCCGTGTAAATAATTTATTACAAGCATAACATGGAGCT CTTGTTGCACTAAAAAGTGGATTACAAATCTCCTCGACTGCTTTAGTGGGGAAAGGAATCAATTATTTATGAACTGTCCGGCCCCGAGTC >16524_16524_12_CHMP1A-FANCA_CHMP1A_chr16_89723990_ENST00000550102_FANCA_chr16_89851372_ENST00000568369_length(amino acids)=989AA_BP=18 MASLLPLRVLLLSLWPWTASFGSTRGYHGCSKKALVFLFTFLSELVPFESPRYLQVHILHPPLVPGKYRSLLTDYISLAKTRLADLKVSI ENMGLYEDLSSAGDITEPHSQALQDVEKAIMVFEHTGNIPVTVMEASIFRRPYYVSHFLPALLTPRVLPKVPDSRVAFIESLKRADKIPP SLYSTYCQACSAAEEKPEDAALGVRAEPNSAEEPLGQLTAALGELRASMTDPSQRDVISAQVAVISERLRAVLGHNEDDSSVEISKIQLS INTPRLEPREHMAVDLLLTSFCQNLMAASSVAPPERQGPWAALFVRTMCGRVLPAVLTRLCQLLRHQGPSLSAPHVLGLAALAVHLGESR SALPEVDVGPPAPGAGLPVPALFDSLLTCRTRDSLFFCLKFCTAAISYSLCKFSSQSRDTLCSCLSPGLIKKFQFLMFRLFSEARQPLSE EDVASLSWRPLHLPSADWQRAALSLWTHRTFREVLKEEDVHLTYQDWLHLELEIQPEADALSDTERQDFHQWAIHEHFLPESSASGGCDG DLQAACTILVNALMDFHQSSRSYDHSENSDLVFGGRTGNEDIISRLQEMVADLELQQDLIVPLGHTPSQEHFLFEIFRRRLQALTSGWSV AASLQRQRELLMYKRILLRLPSSVLCGSSFQAEQPITARCEQFFHLVNSEMRNFCSHGGALTQDITAHFFRGLLNACLRSRDPSLMVDFI LAKCQTKCPLILTSALVWWPSLEPVLLCRWRRHCQSPLPRELQKLQEGRQFASDFLSPEAASPAPNPDWLSAAALHFAIQQVREENIRKQ LKKLDCEREELLVFLFFFSLMGLLSSHLTSNSTTDLPKAFHVCAAILECLEKRKISWLALFQLTESDLRLGRLLLRVAPDQHTRLLPFAF -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for CHMP1A-FANCA |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for CHMP1A-FANCA |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for CHMP1A-FANCA |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | CHMP1A | C0266468 | Congenital pontocerebellar hypoplasia | 1 | GENOMICS_ENGLAND |
| Hgene | CHMP1A | C3554209 | Congenital pontocerebellar hypoplasia type 8 | 1 | CTD_human;GENOMICS_ENGLAND;ORPHANET |
| Tgene | C3469521 | FANCONI ANEMIA, COMPLEMENTATION GROUP A (disorder) | 19 | CLINGEN;GENOMICS_ENGLAND;UNIPROT | |
| Tgene | C1856796 | Estren-Dameshek Variant of Fanconi Anemia | 6 | CLINGEN | |
| Tgene | C1856797 | Estren-Dameshek Variant of Fanconi Pancytopenia | 6 | CLINGEN | |
| Tgene | C0015625 | Fanconi Anemia | 5 | CTD_human;GENOMICS_ENGLAND | |
| Tgene | C0030312 | Pancytopenia | 2 | GENOMICS_ENGLAND | |
| Tgene | C1384666 | hearing impairment | 2 | GENOMICS_ENGLAND | |
| Tgene | C1855710 | Bone marrow hypocellularity | 2 | GENOMICS_ENGLAND | |
| Tgene | C2750866 | Growth retardation, pre- and postnatal | 2 | GENOMICS_ENGLAND | |
| Tgene | C0005684 | Malignant neoplasm of urinary bladder | 1 | CTD_human | |
| Tgene | C0005695 | Bladder Neoplasm | 1 | CTD_human | |
| Tgene | C0010606 | Adenoid Cystic Carcinoma | 1 | CTD_human | |
| Tgene | C0020459 | Hyperinsulinism | 1 | CTD_human | |
| Tgene | C0023418 | leukemia | 1 | CGI;GENOMICS_ENGLAND | |
| Tgene | C0023465 | Acute monocytic leukemia | 1 | GENOMICS_ENGLAND | |
| Tgene | C0023467 | Leukemia, Myelocytic, Acute | 1 | CGI;GENOMICS_ENGLAND | |
| Tgene | C0036095 | Salivary Gland Neoplasms | 1 | CTD_human | |
| Tgene | C0220636 | Malignant neoplasm of salivary gland | 1 | CTD_human | |
| Tgene | C0265219 | Miller Dieker syndrome | 1 | GENOMICS_ENGLAND | |
| Tgene | C1257963 | Endogenous Hyperinsulinism | 1 | CTD_human | |
| Tgene | C1257964 | Exogenous Hyperinsulinism | 1 | CTD_human | |
| Tgene | C1257965 | Compensatory Hyperinsulinemia | 1 | CTD_human | |
| Tgene | C3463824 | MYELODYSPLASTIC SYNDROME | 1 | GENOMICS_ENGLAND | |
| Tgene | C4228778 | Abnormality of radial ray | 1 | GENOMICS_ENGLAND |
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