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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:DTL-PPP2R5A (FusionGDB2 ID:HG51514TG5525) |
Fusion Gene Summary for DTL-PPP2R5A |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: DTL-PPP2R5A | Fusion gene ID: hg51514tg5525 | Hgene | Tgene | Gene symbol | DTL | PPP2R5A | Gene ID | 51514 | 5525 |
| Gene name | denticleless E3 ubiquitin protein ligase homolog | protein phosphatase 2 regulatory subunit B'alpha | |
| Synonyms | CDT2|DCAF2|L2DTL|RAMP | B56A|B56alpha|PR61A | |
| Cytomap | ('DTL')('PPP2R5A') 1q32.3 | 1q32.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | denticleless protein homologDDB1- and CUL4-associated factor 2RA-regulated nuclear matrix-associated proteinlethal(2) denticleless protein homologretinoic acid-regulated nuclear matrix-associated protein | serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoformPP2A B subunit isoform B'-alphaPP2A B subunit isoform B56-alphaPP2A B subunit isoform PR61-alphaPP2A B subunit isoform R5-alphaPP2A, B subunit, B' alpha isoformPP2A, B su | |
| Modification date | 20200320 | 20200313 | |
| UniProtAcc | . | . | |
| Ensembl transtripts involved in fusion gene | ENST00000475419, ENST00000366991, ENST00000542077, | ||
| Fusion gene scores | * DoF score | 8 X 9 X 5=360 | 7 X 7 X 5=245 |
| # samples | 11 | 10 | |
| ** MAII score | log2(11/360*10)=-1.71049338280502 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(10/245*10)=-1.29278174922785 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: DTL [Title/Abstract] AND PPP2R5A [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | DTL(212251604)-PPP2R5A(212506838), # samples:1 DTL(212218100)-PPP2R5A(212502477), # samples:1 DTL(212240227)-PPP2R5A(212502477), # samples:1 DTL(212251604)-PPP2R5A(212506839), # samples:1 | ||
| Anticipated loss of major functional domain due to fusion event. | DTL-PPP2R5A seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. DTL-PPP2R5A seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. DTL-PPP2R5A seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. DTL-PPP2R5A seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | DTL | GO:0000209 | protein polyubiquitination | 18794347 |
| Hgene | DTL | GO:0006511 | ubiquitin-dependent protein catabolic process | 18794347 |
| Hgene | DTL | GO:0006513 | protein monoubiquitination | 20129063 |
| Hgene | DTL | GO:0006974 | cellular response to DNA damage stimulus | 20129063 |
| Hgene | DTL | GO:0009411 | response to UV | 18794347 |
| Hgene | DTL | GO:0019985 | translesion synthesis | 20129063 |
| Tgene | PPP2R5A | GO:0006470 | protein dephosphorylation | 24157919 |
| Fusion gene breakpoints across DTL (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across PPP2R5A (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | SKCM | TCGA-FS-A1ZJ-06A | DTL | chr1 | 212218100 | + | PPP2R5A | chr1 | 212502477 | + |
| ChimerDB4 | STAD | TCGA-HU-A4GJ-01A | DTL | chr1 | 212240227 | + | PPP2R5A | chr1 | 212502477 | + |
| ChimerDB4 | STAD | TCGA-VQ-A8E7-01B | DTL | chr1 | 212251604 | + | PPP2R5A | chr1 | 212506839 | + |
| ChimerDB4 | STAD | TCGA-VQ-A8E7 | DTL | chr1 | 212251604 | + | PPP2R5A | chr1 | 212506838 | + |
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Fusion Gene ORF analysis for DTL-PPP2R5A |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 3UTR-3CDS | ENST00000475419 | ENST00000261461 | DTL | chr1 | 212218100 | + | PPP2R5A | chr1 | 212502477 | + |
| 3UTR-3CDS | ENST00000475419 | ENST00000261461 | DTL | chr1 | 212240227 | + | PPP2R5A | chr1 | 212502477 | + |
| 3UTR-3CDS | ENST00000475419 | ENST00000261461 | DTL | chr1 | 212251604 | + | PPP2R5A | chr1 | 212506839 | + |
| 3UTR-3CDS | ENST00000475419 | ENST00000261461 | DTL | chr1 | 212251604 | + | PPP2R5A | chr1 | 212506838 | + |
| 3UTR-3CDS | ENST00000475419 | ENST00000537030 | DTL | chr1 | 212218100 | + | PPP2R5A | chr1 | 212502477 | + |
| 3UTR-3CDS | ENST00000475419 | ENST00000537030 | DTL | chr1 | 212240227 | + | PPP2R5A | chr1 | 212502477 | + |
| 3UTR-3CDS | ENST00000475419 | ENST00000537030 | DTL | chr1 | 212251604 | + | PPP2R5A | chr1 | 212506839 | + |
| 3UTR-3CDS | ENST00000475419 | ENST00000537030 | DTL | chr1 | 212251604 | + | PPP2R5A | chr1 | 212506838 | + |
| 3UTR-3UTR | ENST00000475419 | ENST00000498129 | DTL | chr1 | 212218100 | + | PPP2R5A | chr1 | 212502477 | + |
| 3UTR-3UTR | ENST00000475419 | ENST00000498129 | DTL | chr1 | 212240227 | + | PPP2R5A | chr1 | 212502477 | + |
| 3UTR-3UTR | ENST00000475419 | ENST00000498129 | DTL | chr1 | 212251604 | + | PPP2R5A | chr1 | 212506839 | + |
| 3UTR-3UTR | ENST00000475419 | ENST00000498129 | DTL | chr1 | 212251604 | + | PPP2R5A | chr1 | 212506838 | + |
| 5CDS-3UTR | ENST00000366991 | ENST00000498129 | DTL | chr1 | 212218100 | + | PPP2R5A | chr1 | 212502477 | + |
| 5CDS-3UTR | ENST00000366991 | ENST00000498129 | DTL | chr1 | 212240227 | + | PPP2R5A | chr1 | 212502477 | + |
| 5CDS-3UTR | ENST00000366991 | ENST00000498129 | DTL | chr1 | 212251604 | + | PPP2R5A | chr1 | 212506839 | + |
| 5CDS-3UTR | ENST00000366991 | ENST00000498129 | DTL | chr1 | 212251604 | + | PPP2R5A | chr1 | 212506838 | + |
| 5CDS-3UTR | ENST00000542077 | ENST00000498129 | DTL | chr1 | 212218100 | + | PPP2R5A | chr1 | 212502477 | + |
| 5CDS-3UTR | ENST00000542077 | ENST00000498129 | DTL | chr1 | 212240227 | + | PPP2R5A | chr1 | 212502477 | + |
| 5CDS-3UTR | ENST00000542077 | ENST00000498129 | DTL | chr1 | 212251604 | + | PPP2R5A | chr1 | 212506839 | + |
| 5CDS-3UTR | ENST00000542077 | ENST00000498129 | DTL | chr1 | 212251604 | + | PPP2R5A | chr1 | 212506838 | + |
| Frame-shift | ENST00000366991 | ENST00000261461 | DTL | chr1 | 212240227 | + | PPP2R5A | chr1 | 212502477 | + |
| Frame-shift | ENST00000366991 | ENST00000537030 | DTL | chr1 | 212240227 | + | PPP2R5A | chr1 | 212502477 | + |
| Frame-shift | ENST00000542077 | ENST00000261461 | DTL | chr1 | 212240227 | + | PPP2R5A | chr1 | 212502477 | + |
| Frame-shift | ENST00000542077 | ENST00000537030 | DTL | chr1 | 212240227 | + | PPP2R5A | chr1 | 212502477 | + |
| In-frame | ENST00000366991 | ENST00000261461 | DTL | chr1 | 212218100 | + | PPP2R5A | chr1 | 212502477 | + |
| In-frame | ENST00000366991 | ENST00000261461 | DTL | chr1 | 212251604 | + | PPP2R5A | chr1 | 212506839 | + |
| In-frame | ENST00000366991 | ENST00000261461 | DTL | chr1 | 212251604 | + | PPP2R5A | chr1 | 212506838 | + |
| In-frame | ENST00000366991 | ENST00000537030 | DTL | chr1 | 212218100 | + | PPP2R5A | chr1 | 212502477 | + |
| In-frame | ENST00000366991 | ENST00000537030 | DTL | chr1 | 212251604 | + | PPP2R5A | chr1 | 212506839 | + |
| In-frame | ENST00000366991 | ENST00000537030 | DTL | chr1 | 212251604 | + | PPP2R5A | chr1 | 212506838 | + |
| In-frame | ENST00000542077 | ENST00000261461 | DTL | chr1 | 212218100 | + | PPP2R5A | chr1 | 212502477 | + |
| In-frame | ENST00000542077 | ENST00000261461 | DTL | chr1 | 212251604 | + | PPP2R5A | chr1 | 212506839 | + |
| In-frame | ENST00000542077 | ENST00000261461 | DTL | chr1 | 212251604 | + | PPP2R5A | chr1 | 212506838 | + |
| In-frame | ENST00000542077 | ENST00000537030 | DTL | chr1 | 212218100 | + | PPP2R5A | chr1 | 212502477 | + |
| In-frame | ENST00000542077 | ENST00000537030 | DTL | chr1 | 212251604 | + | PPP2R5A | chr1 | 212506839 | + |
| In-frame | ENST00000542077 | ENST00000537030 | DTL | chr1 | 212251604 | + | PPP2R5A | chr1 | 212506838 | + |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000366991 | DTL | chr1 | 212251604 | + | ENST00000261461 | PPP2R5A | chr1 | 212506838 | + | 3610 | 1439 | 311 | 2521 | 736 |
| ENST00000366991 | DTL | chr1 | 212251604 | + | ENST00000537030 | PPP2R5A | chr1 | 212506838 | + | 2674 | 1439 | 311 | 2521 | 736 |
| ENST00000542077 | DTL | chr1 | 212251604 | + | ENST00000261461 | PPP2R5A | chr1 | 212506838 | + | 3311 | 1140 | 138 | 2222 | 694 |
| ENST00000542077 | DTL | chr1 | 212251604 | + | ENST00000537030 | PPP2R5A | chr1 | 212506838 | + | 2375 | 1140 | 138 | 2222 | 694 |
| ENST00000366991 | DTL | chr1 | 212218100 | + | ENST00000261461 | PPP2R5A | chr1 | 212502477 | + | 2959 | 591 | 311 | 1870 | 519 |
| ENST00000366991 | DTL | chr1 | 212218100 | + | ENST00000537030 | PPP2R5A | chr1 | 212502477 | + | 2023 | 591 | 311 | 1870 | 519 |
| ENST00000542077 | DTL | chr1 | 212218100 | + | ENST00000261461 | PPP2R5A | chr1 | 212502477 | + | 2660 | 292 | 138 | 1571 | 477 |
| ENST00000542077 | DTL | chr1 | 212218100 | + | ENST00000537030 | PPP2R5A | chr1 | 212502477 | + | 1724 | 292 | 138 | 1571 | 477 |
| ENST00000366991 | DTL | chr1 | 212251604 | + | ENST00000261461 | PPP2R5A | chr1 | 212506839 | + | 3610 | 1439 | 311 | 2521 | 736 |
| ENST00000366991 | DTL | chr1 | 212251604 | + | ENST00000537030 | PPP2R5A | chr1 | 212506839 | + | 2674 | 1439 | 311 | 2521 | 736 |
| ENST00000542077 | DTL | chr1 | 212251604 | + | ENST00000261461 | PPP2R5A | chr1 | 212506839 | + | 3311 | 1140 | 138 | 2222 | 694 |
| ENST00000542077 | DTL | chr1 | 212251604 | + | ENST00000537030 | PPP2R5A | chr1 | 212506839 | + | 2375 | 1140 | 138 | 2222 | 694 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000366991 | ENST00000261461 | DTL | chr1 | 212251604 | + | PPP2R5A | chr1 | 212506838 | + | 0.001030902 | 0.9989691 |
| ENST00000366991 | ENST00000537030 | DTL | chr1 | 212251604 | + | PPP2R5A | chr1 | 212506838 | + | 0.002137892 | 0.99786216 |
| ENST00000542077 | ENST00000261461 | DTL | chr1 | 212251604 | + | PPP2R5A | chr1 | 212506838 | + | 0.000775376 | 0.99922466 |
| ENST00000542077 | ENST00000537030 | DTL | chr1 | 212251604 | + | PPP2R5A | chr1 | 212506838 | + | 0.00170013 | 0.9982999 |
| ENST00000366991 | ENST00000261461 | DTL | chr1 | 212218100 | + | PPP2R5A | chr1 | 212502477 | + | 0.00092028 | 0.9990797 |
| ENST00000366991 | ENST00000537030 | DTL | chr1 | 212218100 | + | PPP2R5A | chr1 | 212502477 | + | 0.002071074 | 0.997929 |
| ENST00000542077 | ENST00000261461 | DTL | chr1 | 212218100 | + | PPP2R5A | chr1 | 212502477 | + | 0.000957342 | 0.9990427 |
| ENST00000542077 | ENST00000537030 | DTL | chr1 | 212218100 | + | PPP2R5A | chr1 | 212502477 | + | 0.002267019 | 0.997733 |
| ENST00000366991 | ENST00000261461 | DTL | chr1 | 212251604 | + | PPP2R5A | chr1 | 212506839 | + | 0.001030902 | 0.9989691 |
| ENST00000366991 | ENST00000537030 | DTL | chr1 | 212251604 | + | PPP2R5A | chr1 | 212506839 | + | 0.002137892 | 0.99786216 |
| ENST00000542077 | ENST00000261461 | DTL | chr1 | 212251604 | + | PPP2R5A | chr1 | 212506839 | + | 0.000775376 | 0.99922466 |
| ENST00000542077 | ENST00000537030 | DTL | chr1 | 212251604 | + | PPP2R5A | chr1 | 212506839 | + | 0.00170013 | 0.9982999 |
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Fusion Genomic Features for DTL-PPP2R5A |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| DTL | chr1 | 212251604 | + | PPP2R5A | chr1 | 212506838 | + | 0.001950928 | 0.998049 |
| DTL | chr1 | 212251604 | + | PPP2R5A | chr1 | 212506838 | + | 0.001950928 | 0.998049 |
| DTL | chr1 | 212218100 | + | PPP2R5A | chr1 | 212502476 | + | 2.68E-09 | 1 |
| DTL | chr1 | 212240227 | + | PPP2R5A | chr1 | 212502476 | + | 2.08E-10 | 1 |
| DTL | chr1 | 212251604 | + | PPP2R5A | chr1 | 212506838 | + | 0.001950928 | 0.998049 |
| DTL | chr1 | 212251604 | + | PPP2R5A | chr1 | 212506838 | + | 0.001950928 | 0.998049 |
| DTL | chr1 | 212218100 | + | PPP2R5A | chr1 | 212502476 | + | 2.68E-09 | 1 |
| DTL | chr1 | 212240227 | + | PPP2R5A | chr1 | 212502476 | + | 2.08E-10 | 1 |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for DTL-PPP2R5A |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr1:212251604/chr1:212506838) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | . |
| FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. | FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | DTL | chr1:212251604 | chr1:212506838 | ENST00000366991 | + | 12 | 15 | 168_171 | 375 | 731.0 | Motif | Note=DDB1-binding motif |
| Hgene | DTL | chr1:212251604 | chr1:212506838 | ENST00000366991 | + | 12 | 15 | 197_203 | 375 | 731.0 | Motif | Nuclear localization signal |
| Hgene | DTL | chr1:212251604 | chr1:212506838 | ENST00000366991 | + | 12 | 15 | 243_246 | 375 | 731.0 | Motif | Note=DDB1-binding motif |
| Hgene | DTL | chr1:212251604 | chr1:212506839 | ENST00000366991 | + | 12 | 15 | 168_171 | 375 | 731.0 | Motif | Note=DDB1-binding motif |
| Hgene | DTL | chr1:212251604 | chr1:212506839 | ENST00000366991 | + | 12 | 15 | 197_203 | 375 | 731.0 | Motif | Nuclear localization signal |
| Hgene | DTL | chr1:212251604 | chr1:212506839 | ENST00000366991 | + | 12 | 15 | 243_246 | 375 | 731.0 | Motif | Note=DDB1-binding motif |
| Hgene | DTL | chr1:212218100 | chr1:212502477 | ENST00000366991 | + | 3 | 15 | 47_89 | 92 | 731.0 | Repeat | Note=WD 1 |
| Hgene | DTL | chr1:212251604 | chr1:212506838 | ENST00000366991 | + | 12 | 15 | 138_178 | 375 | 731.0 | Repeat | Note=WD 3 |
| Hgene | DTL | chr1:212251604 | chr1:212506838 | ENST00000366991 | + | 12 | 15 | 214_253 | 375 | 731.0 | Repeat | Note=WD 4 |
| Hgene | DTL | chr1:212251604 | chr1:212506838 | ENST00000366991 | + | 12 | 15 | 267_308 | 375 | 731.0 | Repeat | Note=WD 5 |
| Hgene | DTL | chr1:212251604 | chr1:212506838 | ENST00000366991 | + | 12 | 15 | 313_354 | 375 | 731.0 | Repeat | Note=WD 6 |
| Hgene | DTL | chr1:212251604 | chr1:212506838 | ENST00000366991 | + | 12 | 15 | 47_89 | 375 | 731.0 | Repeat | Note=WD 1 |
| Hgene | DTL | chr1:212251604 | chr1:212506838 | ENST00000366991 | + | 12 | 15 | 96_135 | 375 | 731.0 | Repeat | Note=WD 2 |
| Hgene | DTL | chr1:212251604 | chr1:212506839 | ENST00000366991 | + | 12 | 15 | 138_178 | 375 | 731.0 | Repeat | Note=WD 3 |
| Hgene | DTL | chr1:212251604 | chr1:212506839 | ENST00000366991 | + | 12 | 15 | 214_253 | 375 | 731.0 | Repeat | Note=WD 4 |
| Hgene | DTL | chr1:212251604 | chr1:212506839 | ENST00000366991 | + | 12 | 15 | 267_308 | 375 | 731.0 | Repeat | Note=WD 5 |
| Hgene | DTL | chr1:212251604 | chr1:212506839 | ENST00000366991 | + | 12 | 15 | 313_354 | 375 | 731.0 | Repeat | Note=WD 6 |
| Hgene | DTL | chr1:212251604 | chr1:212506839 | ENST00000366991 | + | 12 | 15 | 47_89 | 375 | 731.0 | Repeat | Note=WD 1 |
| Hgene | DTL | chr1:212251604 | chr1:212506839 | ENST00000366991 | + | 12 | 15 | 96_135 | 375 | 731.0 | Repeat | Note=WD 2 |
| Tgene | PPP2R5A | chr1:212218100 | chr1:212502477 | ENST00000537030 | 0 | 13 | 2_5 | 3 | 430.0 | Compositional bias | Note=Poly-Ser |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | DTL | chr1:212218100 | chr1:212502477 | ENST00000366991 | + | 3 | 15 | 168_171 | 92 | 731.0 | Motif | Note=DDB1-binding motif |
| Hgene | DTL | chr1:212218100 | chr1:212502477 | ENST00000366991 | + | 3 | 15 | 197_203 | 92 | 731.0 | Motif | Nuclear localization signal |
| Hgene | DTL | chr1:212218100 | chr1:212502477 | ENST00000366991 | + | 3 | 15 | 243_246 | 92 | 731.0 | Motif | Note=DDB1-binding motif |
| Hgene | DTL | chr1:212218100 | chr1:212502477 | ENST00000366991 | + | 3 | 15 | 138_178 | 92 | 731.0 | Repeat | Note=WD 3 |
| Hgene | DTL | chr1:212218100 | chr1:212502477 | ENST00000366991 | + | 3 | 15 | 214_253 | 92 | 731.0 | Repeat | Note=WD 4 |
| Hgene | DTL | chr1:212218100 | chr1:212502477 | ENST00000366991 | + | 3 | 15 | 267_308 | 92 | 731.0 | Repeat | Note=WD 5 |
| Hgene | DTL | chr1:212218100 | chr1:212502477 | ENST00000366991 | + | 3 | 15 | 313_354 | 92 | 731.0 | Repeat | Note=WD 6 |
| Hgene | DTL | chr1:212218100 | chr1:212502477 | ENST00000366991 | + | 3 | 15 | 358_398 | 92 | 731.0 | Repeat | Note=WD 7 |
| Hgene | DTL | chr1:212218100 | chr1:212502477 | ENST00000366991 | + | 3 | 15 | 96_135 | 92 | 731.0 | Repeat | Note=WD 2 |
| Hgene | DTL | chr1:212251604 | chr1:212506838 | ENST00000366991 | + | 12 | 15 | 358_398 | 375 | 731.0 | Repeat | Note=WD 7 |
| Hgene | DTL | chr1:212251604 | chr1:212506839 | ENST00000366991 | + | 12 | 15 | 358_398 | 375 | 731.0 | Repeat | Note=WD 7 |
| Tgene | PPP2R5A | chr1:212218100 | chr1:212502477 | ENST00000261461 | 0 | 13 | 2_5 | 60 | 487.0 | Compositional bias | Note=Poly-Ser | |
| Tgene | PPP2R5A | chr1:212251604 | chr1:212506838 | ENST00000261461 | 1 | 13 | 2_5 | 126 | 487.0 | Compositional bias | Note=Poly-Ser | |
| Tgene | PPP2R5A | chr1:212251604 | chr1:212506838 | ENST00000537030 | 1 | 13 | 2_5 | 69 | 430.0 | Compositional bias | Note=Poly-Ser | |
| Tgene | PPP2R5A | chr1:212251604 | chr1:212506839 | ENST00000261461 | 1 | 13 | 2_5 | 126 | 487.0 | Compositional bias | Note=Poly-Ser | |
| Tgene | PPP2R5A | chr1:212251604 | chr1:212506839 | ENST00000537030 | 1 | 13 | 2_5 | 69 | 430.0 | Compositional bias | Note=Poly-Ser |
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Fusion Gene Sequence for DTL-PPP2R5A |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >24356_24356_1_DTL-PPP2R5A_DTL_chr1_212218100_ENST00000366991_PPP2R5A_chr1_212502477_ENST00000261461_length(transcript)=2959nt_BP=591nt CGCGGTTTGTCCGCGCCTCTGCTACCCCCTGCGCAGGCGCTCAAGGAGCTCTTGGACTCCAGGTTCCCGCGGCTGGGAGAAAAGGAGGCG GGGATCCGAAGGGGGAAATGACTCTGAGGCGCCCGGACGTCGCTCGGAAGCCAATCAGAGAGCGTGACGTCAGTTTGGCGCGGAGTTTGG CGGCCGGGGCTTACAGTGGCGGGAGTTGGAGGCGATAACGATTTGTGTTGTGAGAGGCGCAAGCTGCGATTTCTGCTGAACTTGGAGGCA TTTCTACGACTTTTCTCTCAGCTGAGGCTTTTCCTCCGACCCTGATGCTCTTCAATTCGGTGCTCCGCCAGCCCCAGCTTGGCGTCCTGA GAAATGGATGGTCTTCACAATACCCTCTTCAATCCCTTCTGACTGGTTATCAGTGCAGTGGTAATGATGAACACACTTCTTATGGAGAAA CAGGAGTCCCAGTTCCTCCTTTTGGATGTACCTTCTCTTCTGCTCCCAATATGGAACATGTACTAGCAGTTGCCAATGAAGAAGGCTTTG TTCGATTGTATAACACAGAATCACAAAGTTTCAGAAAGAAGTGCTTCAAAGATGCCACTTCAAATGAACAACAAGAGCTTTTCTGTCAGA AGTTGCAGCAGTGTTGTATACTGTTTGATTTCATGGACTCTGTTTCAGACTTGAAGAGCAAAGAAATTAAAAGAGCAACACTGAATGAAC TGGTTGAGTATGTTTCAACTAATCGTGGTGTAATTGTTGAATCAGCGTATTCTGATATAGTAAAAATGATCAGTGCTAACATCTTCCGTA CACTTCCTCCAAGTGATAATCCAGATTTTGATCCAGAAGAGGATGAACCCACGCTTGAGGCCTCTTGGCCTCACATACAGTTGGTATATG AATTCTTCTTGAGATTTTTGGAGAGCCCTGATTTCCAGCCTAGCATTGCAAAACGATACATTGATCAGAAATTCGTACAACAGCTCCTGG AGCTTTTTGATAGTGAAGATCCCAGAGAACGTGACTTCCTGAAGACTGTTCTGCACCGAATTTATGGGAAATTTCTTGGATTAAGAGCAT TCATCAGAAAACAAATTAACAACATTTTCCTCAGGTTTATATATGAAACAGAACATTTCAATGGTGTTGCTGAACTTCTTGAAATATTAG GAAGTATTATCAATGGCTTTGCATTGCCACTGAAAGCAGAACATAAACAATTTCTAATGAAGGTTCTTATTCCTATGCATACTGCAAAAG GATTAGCTTTGTTTCATGCTCAGCTAGCATATTGTGTTGTACAGTTCCTGGAGAAAGATACAACACTAACAGAGCCAGTGATCAGAGGAC TGCTGAAATTTTGGCCAAAAACCTGCAGTCAGAAAGAGGTGATGTTTTTAGGAGAAATTGAAGAAATCTTAGATGTCATTGAACCAACAC AGTTCAAAAAAATTGAAGAGCCACTTTTCAAGCAGATATCCAAGTGTGTATCCAGTTCTCATTTTCAGGTTGCAGAAAGGGCATTGTACT TCTGGAATAACGAATATATTCTTAGTTTGATTGAGGAGAACATTGATAAAATTCTGCCAATTATGTTTGCCAGTTTGTACAAAATTTCCA AAGAACACTGGAATCCGACCATTGTAGCACTGGTATACAATGTGCTGAAAACCCTAATGGAAATGAATGGCAAGCTTTTCGATGACCTTA CTAGCTCATACAAAGCTGAAAGACAGAGAGAGAAAAAGAAGGAATTGGAACGTGAAGAATTATGGAAAAAATTAGAGGAGCTAAAGCTAA AGAAAGCTCTAGAAAAACAGAATAGTGCTTACAACATGCACAGTATTCTCAGCAATACAAGTGCCGAATAAAAAAAAAGCCTCCCACCTC TGCCGGATAGGCAGAGTTTTGTATGCTTTTTTGAAATATGTAAAAATTACAAAACAAACCTCATCAGTATAATATAATTAAAAGGCCAAT TTTTTCTGGCAACTGTAAATGGAAAAATATATGGACTAAACGTAGCCCTGTGCTGTATCATGGCCATAGTATATTGTAACCTTTGTCTAA TCATTGGATTTATTGTGTCACTTCTGAAGTTTCACAGAAATGAATGAATTTTATCATCTATGATATGAGTGAGATAATTATGGGAGTGGT AAGAATTATGACTTGAATTCTTCTTTGATTGTGTTGCACATAGATATGGTAGTCTGCTCTGTATATTTTTCCCTTTTATAATGTGCTTTT CACACTGCTGCAAACCTTAGTTACATCCTAGGAAAAAATACTTCCTAAAATAAAACTAAGGTATCATCCTTACCCTTCTCTTTGTCTCAC CCAGAAATATGATGGGGGGAATTACCTGCCCTAACCCCTCCCTCAATAAATACATTACTGTACTCTGGAATTTAGGCAAAACCTTAAATC TCCAGGCTTTTTAAAGCACAAAATATAAATAAAAGCTGGGAAAGTAAACCAAAATTCTTCAGATTGTTCCTCATGAATATCCCCCTTCCT CTGCAATTCTCCAGAGTGGTAACAGATGGGTAGAGGCAGCTCAGGTGAATTACCCAGCTTGCCTCTCAATTCATTCCTCCTCTTCCTCTC AAAGGCTGAAGGCAGGGCCTTTCCAGTCCTCACAACCTGTCCTTCACCTAGTCCCTCCTGACCCAGGGATGGAGGCTTTGAGTCCCACAG TGTGGTGATACAGAGCACTAGTTGTCACTGCCTGGCTTTATTTAAAGGAACTGCAGTAGGCTTCCTCTGTAGAGCTCTGAAAAGGTTGAC TATATAGAGGTCTTGTATGTTTTTACTTGGTCAAGTATTTCTCACATCTTTTGTTATCAGAGTACCATTCCAATCTCTTAACTTGCAGTT >24356_24356_1_DTL-PPP2R5A_DTL_chr1_212218100_ENST00000366991_PPP2R5A_chr1_212502477_ENST00000261461_length(amino acids)=519AA_BP=1 MMLFNSVLRQPQLGVLRNGWSSQYPLQSLLTGYQCSGNDEHTSYGETGVPVPPFGCTFSSAPNMEHVLAVANEEGFVRLYNTESQSFRKK CFKDATSNEQQELFCQKLQQCCILFDFMDSVSDLKSKEIKRATLNELVEYVSTNRGVIVESAYSDIVKMISANIFRTLPPSDNPDFDPEE DEPTLEASWPHIQLVYEFFLRFLESPDFQPSIAKRYIDQKFVQQLLELFDSEDPRERDFLKTVLHRIYGKFLGLRAFIRKQINNIFLRFI YETEHFNGVAELLEILGSIINGFALPLKAEHKQFLMKVLIPMHTAKGLALFHAQLAYCVVQFLEKDTTLTEPVIRGLLKFWPKTCSQKEV MFLGEIEEILDVIEPTQFKKIEEPLFKQISKCVSSSHFQVAERALYFWNNEYILSLIEENIDKILPIMFASLYKISKEHWNPTIVALVYN -------------------------------------------------------------- >24356_24356_2_DTL-PPP2R5A_DTL_chr1_212218100_ENST00000366991_PPP2R5A_chr1_212502477_ENST00000537030_length(transcript)=2023nt_BP=591nt CGCGGTTTGTCCGCGCCTCTGCTACCCCCTGCGCAGGCGCTCAAGGAGCTCTTGGACTCCAGGTTCCCGCGGCTGGGAGAAAAGGAGGCG GGGATCCGAAGGGGGAAATGACTCTGAGGCGCCCGGACGTCGCTCGGAAGCCAATCAGAGAGCGTGACGTCAGTTTGGCGCGGAGTTTGG CGGCCGGGGCTTACAGTGGCGGGAGTTGGAGGCGATAACGATTTGTGTTGTGAGAGGCGCAAGCTGCGATTTCTGCTGAACTTGGAGGCA TTTCTACGACTTTTCTCTCAGCTGAGGCTTTTCCTCCGACCCTGATGCTCTTCAATTCGGTGCTCCGCCAGCCCCAGCTTGGCGTCCTGA GAAATGGATGGTCTTCACAATACCCTCTTCAATCCCTTCTGACTGGTTATCAGTGCAGTGGTAATGATGAACACACTTCTTATGGAGAAA CAGGAGTCCCAGTTCCTCCTTTTGGATGTACCTTCTCTTCTGCTCCCAATATGGAACATGTACTAGCAGTTGCCAATGAAGAAGGCTTTG TTCGATTGTATAACACAGAATCACAAAGTTTCAGAAAGAAGTGCTTCAAAGATGCCACTTCAAATGAACAACAAGAGCTTTTCTGTCAGA AGTTGCAGCAGTGTTGTATACTGTTTGATTTCATGGACTCTGTTTCAGACTTGAAGAGCAAAGAAATTAAAAGAGCAACACTGAATGAAC TGGTTGAGTATGTTTCAACTAATCGTGGTGTAATTGTTGAATCAGCGTATTCTGATATAGTAAAAATGATCAGTGCTAACATCTTCCGTA CACTTCCTCCAAGTGATAATCCAGATTTTGATCCAGAAGAGGATGAACCCACGCTTGAGGCCTCTTGGCCTCACATACAGTTGGTATATG AATTCTTCTTGAGATTTTTGGAGAGCCCTGATTTCCAGCCTAGCATTGCAAAACGATACATTGATCAGAAATTCGTACAACAGCTCCTGG AGCTTTTTGATAGTGAAGATCCCAGAGAACGTGACTTCCTGAAGACTGTTCTGCACCGAATTTATGGGAAATTTCTTGGATTAAGAGCAT TCATCAGAAAACAAATTAACAACATTTTCCTCAGGTTTATATATGAAACAGAACATTTCAATGGTGTTGCTGAACTTCTTGAAATATTAG GAAGTATTATCAATGGCTTTGCATTGCCACTGAAAGCAGAACATAAACAATTTCTAATGAAGGTTCTTATTCCTATGCATACTGCAAAAG GATTAGCTTTGTTTCATGCTCAGCTAGCATATTGTGTTGTACAGTTCCTGGAGAAAGATACAACACTAACAGAGCCAGTGATCAGAGGAC TGCTGAAATTTTGGCCAAAAACCTGCAGTCAGAAAGAGGTGATGTTTTTAGGAGAAATTGAAGAAATCTTAGATGTCATTGAACCAACAC AGTTCAAAAAAATTGAAGAGCCACTTTTCAAGCAGATATCCAAGTGTGTATCCAGTTCTCATTTTCAGGTTGCAGAAAGGGCATTGTACT TCTGGAATAACGAATATATTCTTAGTTTGATTGAGGAGAACATTGATAAAATTCTGCCAATTATGTTTGCCAGTTTGTACAAAATTTCCA AAGAACACTGGAATCCGACCATTGTAGCACTGGTATACAATGTGCTGAAAACCCTAATGGAAATGAATGGCAAGCTTTTCGATGACCTTA CTAGCTCATACAAAGCTGAAAGACAGAGAGAGAAAAAGAAGGAATTGGAACGTGAAGAATTATGGAAAAAATTAGAGGAGCTAAAGCTAA AGAAAGCTCTAGAAAAACAGAATAGTGCTTACAACATGCACAGTATTCTCAGCAATACAAGTGCCGAATAAAAAAAAAGCCTCCCACCTC TGCCGGATAGGCAGAGTTTTGTATGCTTTTTTGAAATATGTAAAAATTACAAAACAAACCTCATCAGTATAATATAATTAAAAGGCCAAT >24356_24356_2_DTL-PPP2R5A_DTL_chr1_212218100_ENST00000366991_PPP2R5A_chr1_212502477_ENST00000537030_length(amino acids)=519AA_BP=1 MMLFNSVLRQPQLGVLRNGWSSQYPLQSLLTGYQCSGNDEHTSYGETGVPVPPFGCTFSSAPNMEHVLAVANEEGFVRLYNTESQSFRKK CFKDATSNEQQELFCQKLQQCCILFDFMDSVSDLKSKEIKRATLNELVEYVSTNRGVIVESAYSDIVKMISANIFRTLPPSDNPDFDPEE DEPTLEASWPHIQLVYEFFLRFLESPDFQPSIAKRYIDQKFVQQLLELFDSEDPRERDFLKTVLHRIYGKFLGLRAFIRKQINNIFLRFI YETEHFNGVAELLEILGSIINGFALPLKAEHKQFLMKVLIPMHTAKGLALFHAQLAYCVVQFLEKDTTLTEPVIRGLLKFWPKTCSQKEV MFLGEIEEILDVIEPTQFKKIEEPLFKQISKCVSSSHFQVAERALYFWNNEYILSLIEENIDKILPIMFASLYKISKEHWNPTIVALVYN -------------------------------------------------------------- >24356_24356_3_DTL-PPP2R5A_DTL_chr1_212218100_ENST00000542077_PPP2R5A_chr1_212502477_ENST00000261461_length(transcript)=2660nt_BP=292nt AGTTTGGCGGCCGGGGCTTACAGTGGCGGGAGTTGGAGGCGATAACGATTTGTGTTGTGAGAGGCGCAAGCTGCGATTTCTGCTGAACTT GGAGGCATTTCTACGACTTTTCTCTCAGCTGAGGCTTTTCCTCCGACCCTGATGCTCTTCAATTCGGTGCTCCGCCAGCCCCAGCTTGGC GTCCTGAGAAATGCTCCCAATATGGAACATGTACTAGCAGTTGCCAATGAAGAAGGCTTTGTTCGATTGTATAACACAGAATCACAAAGT TTCAGAAAGAAGTGCTTCAAAGATGCCACTTCAAATGAACAACAAGAGCTTTTCTGTCAGAAGTTGCAGCAGTGTTGTATACTGTTTGAT TTCATGGACTCTGTTTCAGACTTGAAGAGCAAAGAAATTAAAAGAGCAACACTGAATGAACTGGTTGAGTATGTTTCAACTAATCGTGGT GTAATTGTTGAATCAGCGTATTCTGATATAGTAAAAATGATCAGTGCTAACATCTTCCGTACACTTCCTCCAAGTGATAATCCAGATTTT GATCCAGAAGAGGATGAACCCACGCTTGAGGCCTCTTGGCCTCACATACAGTTGGTATATGAATTCTTCTTGAGATTTTTGGAGAGCCCT GATTTCCAGCCTAGCATTGCAAAACGATACATTGATCAGAAATTCGTACAACAGCTCCTGGAGCTTTTTGATAGTGAAGATCCCAGAGAA CGTGACTTCCTGAAGACTGTTCTGCACCGAATTTATGGGAAATTTCTTGGATTAAGAGCATTCATCAGAAAACAAATTAACAACATTTTC CTCAGGTTTATATATGAAACAGAACATTTCAATGGTGTTGCTGAACTTCTTGAAATATTAGGAAGTATTATCAATGGCTTTGCATTGCCA CTGAAAGCAGAACATAAACAATTTCTAATGAAGGTTCTTATTCCTATGCATACTGCAAAAGGATTAGCTTTGTTTCATGCTCAGCTAGCA TATTGTGTTGTACAGTTCCTGGAGAAAGATACAACACTAACAGAGCCAGTGATCAGAGGACTGCTGAAATTTTGGCCAAAAACCTGCAGT CAGAAAGAGGTGATGTTTTTAGGAGAAATTGAAGAAATCTTAGATGTCATTGAACCAACACAGTTCAAAAAAATTGAAGAGCCACTTTTC AAGCAGATATCCAAGTGTGTATCCAGTTCTCATTTTCAGGTTGCAGAAAGGGCATTGTACTTCTGGAATAACGAATATATTCTTAGTTTG ATTGAGGAGAACATTGATAAAATTCTGCCAATTATGTTTGCCAGTTTGTACAAAATTTCCAAAGAACACTGGAATCCGACCATTGTAGCA CTGGTATACAATGTGCTGAAAACCCTAATGGAAATGAATGGCAAGCTTTTCGATGACCTTACTAGCTCATACAAAGCTGAAAGACAGAGA GAGAAAAAGAAGGAATTGGAACGTGAAGAATTATGGAAAAAATTAGAGGAGCTAAAGCTAAAGAAAGCTCTAGAAAAACAGAATAGTGCT TACAACATGCACAGTATTCTCAGCAATACAAGTGCCGAATAAAAAAAAAGCCTCCCACCTCTGCCGGATAGGCAGAGTTTTGTATGCTTT TTTGAAATATGTAAAAATTACAAAACAAACCTCATCAGTATAATATAATTAAAAGGCCAATTTTTTCTGGCAACTGTAAATGGAAAAATA TATGGACTAAACGTAGCCCTGTGCTGTATCATGGCCATAGTATATTGTAACCTTTGTCTAATCATTGGATTTATTGTGTCACTTCTGAAG TTTCACAGAAATGAATGAATTTTATCATCTATGATATGAGTGAGATAATTATGGGAGTGGTAAGAATTATGACTTGAATTCTTCTTTGAT TGTGTTGCACATAGATATGGTAGTCTGCTCTGTATATTTTTCCCTTTTATAATGTGCTTTTCACACTGCTGCAAACCTTAGTTACATCCT AGGAAAAAATACTTCCTAAAATAAAACTAAGGTATCATCCTTACCCTTCTCTTTGTCTCACCCAGAAATATGATGGGGGGAATTACCTGC CCTAACCCCTCCCTCAATAAATACATTACTGTACTCTGGAATTTAGGCAAAACCTTAAATCTCCAGGCTTTTTAAAGCACAAAATATAAA TAAAAGCTGGGAAAGTAAACCAAAATTCTTCAGATTGTTCCTCATGAATATCCCCCTTCCTCTGCAATTCTCCAGAGTGGTAACAGATGG GTAGAGGCAGCTCAGGTGAATTACCCAGCTTGCCTCTCAATTCATTCCTCCTCTTCCTCTCAAAGGCTGAAGGCAGGGCCTTTCCAGTCC TCACAACCTGTCCTTCACCTAGTCCCTCCTGACCCAGGGATGGAGGCTTTGAGTCCCACAGTGTGGTGATACAGAGCACTAGTTGTCACT GCCTGGCTTTATTTAAAGGAACTGCAGTAGGCTTCCTCTGTAGAGCTCTGAAAAGGTTGACTATATAGAGGTCTTGTATGTTTTTACTTG GTCAAGTATTTCTCACATCTTTTGTTATCAGAGTACCATTCCAATCTCTTAACTTGCAGTTGTGTGGAAAACTGTTTTGTAATGAAAGAT >24356_24356_3_DTL-PPP2R5A_DTL_chr1_212218100_ENST00000542077_PPP2R5A_chr1_212502477_ENST00000261461_length(amino acids)=477AA_BP=1 MMLFNSVLRQPQLGVLRNAPNMEHVLAVANEEGFVRLYNTESQSFRKKCFKDATSNEQQELFCQKLQQCCILFDFMDSVSDLKSKEIKRA TLNELVEYVSTNRGVIVESAYSDIVKMISANIFRTLPPSDNPDFDPEEDEPTLEASWPHIQLVYEFFLRFLESPDFQPSIAKRYIDQKFV QQLLELFDSEDPRERDFLKTVLHRIYGKFLGLRAFIRKQINNIFLRFIYETEHFNGVAELLEILGSIINGFALPLKAEHKQFLMKVLIPM HTAKGLALFHAQLAYCVVQFLEKDTTLTEPVIRGLLKFWPKTCSQKEVMFLGEIEEILDVIEPTQFKKIEEPLFKQISKCVSSSHFQVAE RALYFWNNEYILSLIEENIDKILPIMFASLYKISKEHWNPTIVALVYNVLKTLMEMNGKLFDDLTSSYKAERQREKKKELEREELWKKLE -------------------------------------------------------------- >24356_24356_4_DTL-PPP2R5A_DTL_chr1_212218100_ENST00000542077_PPP2R5A_chr1_212502477_ENST00000537030_length(transcript)=1724nt_BP=292nt AGTTTGGCGGCCGGGGCTTACAGTGGCGGGAGTTGGAGGCGATAACGATTTGTGTTGTGAGAGGCGCAAGCTGCGATTTCTGCTGAACTT GGAGGCATTTCTACGACTTTTCTCTCAGCTGAGGCTTTTCCTCCGACCCTGATGCTCTTCAATTCGGTGCTCCGCCAGCCCCAGCTTGGC GTCCTGAGAAATGCTCCCAATATGGAACATGTACTAGCAGTTGCCAATGAAGAAGGCTTTGTTCGATTGTATAACACAGAATCACAAAGT TTCAGAAAGAAGTGCTTCAAAGATGCCACTTCAAATGAACAACAAGAGCTTTTCTGTCAGAAGTTGCAGCAGTGTTGTATACTGTTTGAT TTCATGGACTCTGTTTCAGACTTGAAGAGCAAAGAAATTAAAAGAGCAACACTGAATGAACTGGTTGAGTATGTTTCAACTAATCGTGGT GTAATTGTTGAATCAGCGTATTCTGATATAGTAAAAATGATCAGTGCTAACATCTTCCGTACACTTCCTCCAAGTGATAATCCAGATTTT GATCCAGAAGAGGATGAACCCACGCTTGAGGCCTCTTGGCCTCACATACAGTTGGTATATGAATTCTTCTTGAGATTTTTGGAGAGCCCT GATTTCCAGCCTAGCATTGCAAAACGATACATTGATCAGAAATTCGTACAACAGCTCCTGGAGCTTTTTGATAGTGAAGATCCCAGAGAA CGTGACTTCCTGAAGACTGTTCTGCACCGAATTTATGGGAAATTTCTTGGATTAAGAGCATTCATCAGAAAACAAATTAACAACATTTTC CTCAGGTTTATATATGAAACAGAACATTTCAATGGTGTTGCTGAACTTCTTGAAATATTAGGAAGTATTATCAATGGCTTTGCATTGCCA CTGAAAGCAGAACATAAACAATTTCTAATGAAGGTTCTTATTCCTATGCATACTGCAAAAGGATTAGCTTTGTTTCATGCTCAGCTAGCA TATTGTGTTGTACAGTTCCTGGAGAAAGATACAACACTAACAGAGCCAGTGATCAGAGGACTGCTGAAATTTTGGCCAAAAACCTGCAGT CAGAAAGAGGTGATGTTTTTAGGAGAAATTGAAGAAATCTTAGATGTCATTGAACCAACACAGTTCAAAAAAATTGAAGAGCCACTTTTC AAGCAGATATCCAAGTGTGTATCCAGTTCTCATTTTCAGGTTGCAGAAAGGGCATTGTACTTCTGGAATAACGAATATATTCTTAGTTTG ATTGAGGAGAACATTGATAAAATTCTGCCAATTATGTTTGCCAGTTTGTACAAAATTTCCAAAGAACACTGGAATCCGACCATTGTAGCA CTGGTATACAATGTGCTGAAAACCCTAATGGAAATGAATGGCAAGCTTTTCGATGACCTTACTAGCTCATACAAAGCTGAAAGACAGAGA GAGAAAAAGAAGGAATTGGAACGTGAAGAATTATGGAAAAAATTAGAGGAGCTAAAGCTAAAGAAAGCTCTAGAAAAACAGAATAGTGCT TACAACATGCACAGTATTCTCAGCAATACAAGTGCCGAATAAAAAAAAAGCCTCCCACCTCTGCCGGATAGGCAGAGTTTTGTATGCTTT TTTGAAATATGTAAAAATTACAAAACAAACCTCATCAGTATAATATAATTAAAAGGCCAATTTTTTCTGGCAACTGTAAATGGAAAAATA >24356_24356_4_DTL-PPP2R5A_DTL_chr1_212218100_ENST00000542077_PPP2R5A_chr1_212502477_ENST00000537030_length(amino acids)=477AA_BP=1 MMLFNSVLRQPQLGVLRNAPNMEHVLAVANEEGFVRLYNTESQSFRKKCFKDATSNEQQELFCQKLQQCCILFDFMDSVSDLKSKEIKRA TLNELVEYVSTNRGVIVESAYSDIVKMISANIFRTLPPSDNPDFDPEEDEPTLEASWPHIQLVYEFFLRFLESPDFQPSIAKRYIDQKFV QQLLELFDSEDPRERDFLKTVLHRIYGKFLGLRAFIRKQINNIFLRFIYETEHFNGVAELLEILGSIINGFALPLKAEHKQFLMKVLIPM HTAKGLALFHAQLAYCVVQFLEKDTTLTEPVIRGLLKFWPKTCSQKEVMFLGEIEEILDVIEPTQFKKIEEPLFKQISKCVSSSHFQVAE RALYFWNNEYILSLIEENIDKILPIMFASLYKISKEHWNPTIVALVYNVLKTLMEMNGKLFDDLTSSYKAERQREKKKELEREELWKKLE -------------------------------------------------------------- >24356_24356_5_DTL-PPP2R5A_DTL_chr1_212251604_ENST00000366991_PPP2R5A_chr1_212506838_ENST00000261461_length(transcript)=3610nt_BP=1439nt CGCGGTTTGTCCGCGCCTCTGCTACCCCCTGCGCAGGCGCTCAAGGAGCTCTTGGACTCCAGGTTCCCGCGGCTGGGAGAAAAGGAGGCG GGGATCCGAAGGGGGAAATGACTCTGAGGCGCCCGGACGTCGCTCGGAAGCCAATCAGAGAGCGTGACGTCAGTTTGGCGCGGAGTTTGG CGGCCGGGGCTTACAGTGGCGGGAGTTGGAGGCGATAACGATTTGTGTTGTGAGAGGCGCAAGCTGCGATTTCTGCTGAACTTGGAGGCA TTTCTACGACTTTTCTCTCAGCTGAGGCTTTTCCTCCGACCCTGATGCTCTTCAATTCGGTGCTCCGCCAGCCCCAGCTTGGCGTCCTGA GAAATGGATGGTCTTCACAATACCCTCTTCAATCCCTTCTGACTGGTTATCAGTGCAGTGGTAATGATGAACACACTTCTTATGGAGAAA CAGGAGTCCCAGTTCCTCCTTTTGGATGTACCTTCTCTTCTGCTCCCAATATGGAACATGTACTAGCAGTTGCCAATGAAGAAGGCTTTG TTCGATTGTATAACACAGAATCACAAAGTTTCAGAAAGAAGTGCTTCAAAGAATGGATGGCTCACTGGAATGCCGTCTTTGACCTGGCCT GGGTTCCTGGTGAACTTAAACTTGTTACAGCAGCAGGTGATCAAACAGCCAAATTTTGGGACGTAAAAGCTGGTGAGCTGATTGGAACAT GCAAAGGTCATCAATGCAGCCTCAAGTCAGTTGCCTTTTCTAAGTTTGAGAAAGCTGTATTCTGTACGGGTGGAAGAGATGGCAACATTA TGGTCTGGGATACCAGGTGCAACAAAAAAGATGGGTTTTATAGGCAAGTGAATCAAATCAGTGGAGCTCACAATACCTCAGACAAGCAAA CCCCTTCAAAACCCAAGAAGAAACAGAATTCAAAAGGACTTGCTCCTTCTGTGGATTTCCAGCAAAGTGTTACTGTGGTCCTCTTTCAAG ACGAGAATACCTTAGTCTCAGCAGGAGCTGTGGATGGGATAATCAAAGTATGGGATTTACGTAAGAATTATACTGCTTATCGACAAGAAC CCATAGCATCCAAGTCTTTCCTGTACCCAGGTAGCAGCACTCGAAAACTTGGATATTCAAGTCTGATTTTGGATTCCACTGGCTCTACTT TATTTGCTAATTGCACAGACGATAACATCTACATGTTTAATATGACTGGGTTGAAGACTTCTCCAGTGGCTATTTTCAATGGACACCAGA ACTCTACCTTTTATGTAAAATCCAGCCTTAGTCCAGATGACCAGTTTTTAGTCAGTGGCTCAAGTGATGAAGCTGCCTACATATGGAAGG TCTCCACACCCTGGCAACCTCCTACTGTGCTCCTGGGTCATTCTCAAGAGGTCACGTCTGTGTGCTGGTGTCCATCTGACTTCACAAAGA TCAGTGCTAACATCTTCCGTACACTTCCTCCAAGTGATAATCCAGATTTTGATCCAGAAGAGGATGAACCCACGCTTGAGGCCTCTTGGC CTCACATACAGTTGGTATATGAATTCTTCTTGAGATTTTTGGAGAGCCCTGATTTCCAGCCTAGCATTGCAAAACGATACATTGATCAGA AATTCGTACAACAGCTCCTGGAGCTTTTTGATAGTGAAGATCCCAGAGAACGTGACTTCCTGAAGACTGTTCTGCACCGAATTTATGGGA AATTTCTTGGATTAAGAGCATTCATCAGAAAACAAATTAACAACATTTTCCTCAGGTTTATATATGAAACAGAACATTTCAATGGTGTTG CTGAACTTCTTGAAATATTAGGAAGTATTATCAATGGCTTTGCATTGCCACTGAAAGCAGAACATAAACAATTTCTAATGAAGGTTCTTA TTCCTATGCATACTGCAAAAGGATTAGCTTTGTTTCATGCTCAGCTAGCATATTGTGTTGTACAGTTCCTGGAGAAAGATACAACACTAA CAGAGCCAGTGATCAGAGGACTGCTGAAATTTTGGCCAAAAACCTGCAGTCAGAAAGAGGTGATGTTTTTAGGAGAAATTGAAGAAATCT TAGATGTCATTGAACCAACACAGTTCAAAAAAATTGAAGAGCCACTTTTCAAGCAGATATCCAAGTGTGTATCCAGTTCTCATTTTCAGG TTGCAGAAAGGGCATTGTACTTCTGGAATAACGAATATATTCTTAGTTTGATTGAGGAGAACATTGATAAAATTCTGCCAATTATGTTTG CCAGTTTGTACAAAATTTCCAAAGAACACTGGAATCCGACCATTGTAGCACTGGTATACAATGTGCTGAAAACCCTAATGGAAATGAATG GCAAGCTTTTCGATGACCTTACTAGCTCATACAAAGCTGAAAGACAGAGAGAGAAAAAGAAGGAATTGGAACGTGAAGAATTATGGAAAA AATTAGAGGAGCTAAAGCTAAAGAAAGCTCTAGAAAAACAGAATAGTGCTTACAACATGCACAGTATTCTCAGCAATACAAGTGCCGAAT AAAAAAAAAGCCTCCCACCTCTGCCGGATAGGCAGAGTTTTGTATGCTTTTTTGAAATATGTAAAAATTACAAAACAAACCTCATCAGTA TAATATAATTAAAAGGCCAATTTTTTCTGGCAACTGTAAATGGAAAAATATATGGACTAAACGTAGCCCTGTGCTGTATCATGGCCATAG TATATTGTAACCTTTGTCTAATCATTGGATTTATTGTGTCACTTCTGAAGTTTCACAGAAATGAATGAATTTTATCATCTATGATATGAG TGAGATAATTATGGGAGTGGTAAGAATTATGACTTGAATTCTTCTTTGATTGTGTTGCACATAGATATGGTAGTCTGCTCTGTATATTTT TCCCTTTTATAATGTGCTTTTCACACTGCTGCAAACCTTAGTTACATCCTAGGAAAAAATACTTCCTAAAATAAAACTAAGGTATCATCC TTACCCTTCTCTTTGTCTCACCCAGAAATATGATGGGGGGAATTACCTGCCCTAACCCCTCCCTCAATAAATACATTACTGTACTCTGGA ATTTAGGCAAAACCTTAAATCTCCAGGCTTTTTAAAGCACAAAATATAAATAAAAGCTGGGAAAGTAAACCAAAATTCTTCAGATTGTTC CTCATGAATATCCCCCTTCCTCTGCAATTCTCCAGAGTGGTAACAGATGGGTAGAGGCAGCTCAGGTGAATTACCCAGCTTGCCTCTCAA TTCATTCCTCCTCTTCCTCTCAAAGGCTGAAGGCAGGGCCTTTCCAGTCCTCACAACCTGTCCTTCACCTAGTCCCTCCTGACCCAGGGA TGGAGGCTTTGAGTCCCACAGTGTGGTGATACAGAGCACTAGTTGTCACTGCCTGGCTTTATTTAAAGGAACTGCAGTAGGCTTCCTCTG TAGAGCTCTGAAAAGGTTGACTATATAGAGGTCTTGTATGTTTTTACTTGGTCAAGTATTTCTCACATCTTTTGTTATCAGAGTACCATT CCAATCTCTTAACTTGCAGTTGTGTGGAAAACTGTTTTGTAATGAAAGATCTTCATTGGGGGATTGAGCAGCATTTAATAAAGTCTATGT >24356_24356_5_DTL-PPP2R5A_DTL_chr1_212251604_ENST00000366991_PPP2R5A_chr1_212506838_ENST00000261461_length(amino acids)=736AA_BP=1 MMLFNSVLRQPQLGVLRNGWSSQYPLQSLLTGYQCSGNDEHTSYGETGVPVPPFGCTFSSAPNMEHVLAVANEEGFVRLYNTESQSFRKK CFKEWMAHWNAVFDLAWVPGELKLVTAAGDQTAKFWDVKAGELIGTCKGHQCSLKSVAFSKFEKAVFCTGGRDGNIMVWDTRCNKKDGFY RQVNQISGAHNTSDKQTPSKPKKKQNSKGLAPSVDFQQSVTVVLFQDENTLVSAGAVDGIIKVWDLRKNYTAYRQEPIASKSFLYPGSST RKLGYSSLILDSTGSTLFANCTDDNIYMFNMTGLKTSPVAIFNGHQNSTFYVKSSLSPDDQFLVSGSSDEAAYIWKVSTPWQPPTVLLGH SQEVTSVCWCPSDFTKISANIFRTLPPSDNPDFDPEEDEPTLEASWPHIQLVYEFFLRFLESPDFQPSIAKRYIDQKFVQQLLELFDSED PRERDFLKTVLHRIYGKFLGLRAFIRKQINNIFLRFIYETEHFNGVAELLEILGSIINGFALPLKAEHKQFLMKVLIPMHTAKGLALFHA QLAYCVVQFLEKDTTLTEPVIRGLLKFWPKTCSQKEVMFLGEIEEILDVIEPTQFKKIEEPLFKQISKCVSSSHFQVAERALYFWNNEYI LSLIEENIDKILPIMFASLYKISKEHWNPTIVALVYNVLKTLMEMNGKLFDDLTSSYKAERQREKKKELEREELWKKLEELKLKKALEKQ -------------------------------------------------------------- >24356_24356_6_DTL-PPP2R5A_DTL_chr1_212251604_ENST00000366991_PPP2R5A_chr1_212506838_ENST00000537030_length(transcript)=2674nt_BP=1439nt CGCGGTTTGTCCGCGCCTCTGCTACCCCCTGCGCAGGCGCTCAAGGAGCTCTTGGACTCCAGGTTCCCGCGGCTGGGAGAAAAGGAGGCG GGGATCCGAAGGGGGAAATGACTCTGAGGCGCCCGGACGTCGCTCGGAAGCCAATCAGAGAGCGTGACGTCAGTTTGGCGCGGAGTTTGG CGGCCGGGGCTTACAGTGGCGGGAGTTGGAGGCGATAACGATTTGTGTTGTGAGAGGCGCAAGCTGCGATTTCTGCTGAACTTGGAGGCA TTTCTACGACTTTTCTCTCAGCTGAGGCTTTTCCTCCGACCCTGATGCTCTTCAATTCGGTGCTCCGCCAGCCCCAGCTTGGCGTCCTGA GAAATGGATGGTCTTCACAATACCCTCTTCAATCCCTTCTGACTGGTTATCAGTGCAGTGGTAATGATGAACACACTTCTTATGGAGAAA CAGGAGTCCCAGTTCCTCCTTTTGGATGTACCTTCTCTTCTGCTCCCAATATGGAACATGTACTAGCAGTTGCCAATGAAGAAGGCTTTG TTCGATTGTATAACACAGAATCACAAAGTTTCAGAAAGAAGTGCTTCAAAGAATGGATGGCTCACTGGAATGCCGTCTTTGACCTGGCCT GGGTTCCTGGTGAACTTAAACTTGTTACAGCAGCAGGTGATCAAACAGCCAAATTTTGGGACGTAAAAGCTGGTGAGCTGATTGGAACAT GCAAAGGTCATCAATGCAGCCTCAAGTCAGTTGCCTTTTCTAAGTTTGAGAAAGCTGTATTCTGTACGGGTGGAAGAGATGGCAACATTA TGGTCTGGGATACCAGGTGCAACAAAAAAGATGGGTTTTATAGGCAAGTGAATCAAATCAGTGGAGCTCACAATACCTCAGACAAGCAAA CCCCTTCAAAACCCAAGAAGAAACAGAATTCAAAAGGACTTGCTCCTTCTGTGGATTTCCAGCAAAGTGTTACTGTGGTCCTCTTTCAAG ACGAGAATACCTTAGTCTCAGCAGGAGCTGTGGATGGGATAATCAAAGTATGGGATTTACGTAAGAATTATACTGCTTATCGACAAGAAC CCATAGCATCCAAGTCTTTCCTGTACCCAGGTAGCAGCACTCGAAAACTTGGATATTCAAGTCTGATTTTGGATTCCACTGGCTCTACTT TATTTGCTAATTGCACAGACGATAACATCTACATGTTTAATATGACTGGGTTGAAGACTTCTCCAGTGGCTATTTTCAATGGACACCAGA ACTCTACCTTTTATGTAAAATCCAGCCTTAGTCCAGATGACCAGTTTTTAGTCAGTGGCTCAAGTGATGAAGCTGCCTACATATGGAAGG TCTCCACACCCTGGCAACCTCCTACTGTGCTCCTGGGTCATTCTCAAGAGGTCACGTCTGTGTGCTGGTGTCCATCTGACTTCACAAAGA TCAGTGCTAACATCTTCCGTACACTTCCTCCAAGTGATAATCCAGATTTTGATCCAGAAGAGGATGAACCCACGCTTGAGGCCTCTTGGC CTCACATACAGTTGGTATATGAATTCTTCTTGAGATTTTTGGAGAGCCCTGATTTCCAGCCTAGCATTGCAAAACGATACATTGATCAGA AATTCGTACAACAGCTCCTGGAGCTTTTTGATAGTGAAGATCCCAGAGAACGTGACTTCCTGAAGACTGTTCTGCACCGAATTTATGGGA AATTTCTTGGATTAAGAGCATTCATCAGAAAACAAATTAACAACATTTTCCTCAGGTTTATATATGAAACAGAACATTTCAATGGTGTTG CTGAACTTCTTGAAATATTAGGAAGTATTATCAATGGCTTTGCATTGCCACTGAAAGCAGAACATAAACAATTTCTAATGAAGGTTCTTA TTCCTATGCATACTGCAAAAGGATTAGCTTTGTTTCATGCTCAGCTAGCATATTGTGTTGTACAGTTCCTGGAGAAAGATACAACACTAA CAGAGCCAGTGATCAGAGGACTGCTGAAATTTTGGCCAAAAACCTGCAGTCAGAAAGAGGTGATGTTTTTAGGAGAAATTGAAGAAATCT TAGATGTCATTGAACCAACACAGTTCAAAAAAATTGAAGAGCCACTTTTCAAGCAGATATCCAAGTGTGTATCCAGTTCTCATTTTCAGG TTGCAGAAAGGGCATTGTACTTCTGGAATAACGAATATATTCTTAGTTTGATTGAGGAGAACATTGATAAAATTCTGCCAATTATGTTTG CCAGTTTGTACAAAATTTCCAAAGAACACTGGAATCCGACCATTGTAGCACTGGTATACAATGTGCTGAAAACCCTAATGGAAATGAATG GCAAGCTTTTCGATGACCTTACTAGCTCATACAAAGCTGAAAGACAGAGAGAGAAAAAGAAGGAATTGGAACGTGAAGAATTATGGAAAA AATTAGAGGAGCTAAAGCTAAAGAAAGCTCTAGAAAAACAGAATAGTGCTTACAACATGCACAGTATTCTCAGCAATACAAGTGCCGAAT AAAAAAAAAGCCTCCCACCTCTGCCGGATAGGCAGAGTTTTGTATGCTTTTTTGAAATATGTAAAAATTACAAAACAAACCTCATCAGTA >24356_24356_6_DTL-PPP2R5A_DTL_chr1_212251604_ENST00000366991_PPP2R5A_chr1_212506838_ENST00000537030_length(amino acids)=736AA_BP=1 MMLFNSVLRQPQLGVLRNGWSSQYPLQSLLTGYQCSGNDEHTSYGETGVPVPPFGCTFSSAPNMEHVLAVANEEGFVRLYNTESQSFRKK CFKEWMAHWNAVFDLAWVPGELKLVTAAGDQTAKFWDVKAGELIGTCKGHQCSLKSVAFSKFEKAVFCTGGRDGNIMVWDTRCNKKDGFY RQVNQISGAHNTSDKQTPSKPKKKQNSKGLAPSVDFQQSVTVVLFQDENTLVSAGAVDGIIKVWDLRKNYTAYRQEPIASKSFLYPGSST RKLGYSSLILDSTGSTLFANCTDDNIYMFNMTGLKTSPVAIFNGHQNSTFYVKSSLSPDDQFLVSGSSDEAAYIWKVSTPWQPPTVLLGH SQEVTSVCWCPSDFTKISANIFRTLPPSDNPDFDPEEDEPTLEASWPHIQLVYEFFLRFLESPDFQPSIAKRYIDQKFVQQLLELFDSED PRERDFLKTVLHRIYGKFLGLRAFIRKQINNIFLRFIYETEHFNGVAELLEILGSIINGFALPLKAEHKQFLMKVLIPMHTAKGLALFHA QLAYCVVQFLEKDTTLTEPVIRGLLKFWPKTCSQKEVMFLGEIEEILDVIEPTQFKKIEEPLFKQISKCVSSSHFQVAERALYFWNNEYI LSLIEENIDKILPIMFASLYKISKEHWNPTIVALVYNVLKTLMEMNGKLFDDLTSSYKAERQREKKKELEREELWKKLEELKLKKALEKQ -------------------------------------------------------------- >24356_24356_7_DTL-PPP2R5A_DTL_chr1_212251604_ENST00000366991_PPP2R5A_chr1_212506839_ENST00000261461_length(transcript)=3610nt_BP=1439nt CGCGGTTTGTCCGCGCCTCTGCTACCCCCTGCGCAGGCGCTCAAGGAGCTCTTGGACTCCAGGTTCCCGCGGCTGGGAGAAAAGGAGGCG GGGATCCGAAGGGGGAAATGACTCTGAGGCGCCCGGACGTCGCTCGGAAGCCAATCAGAGAGCGTGACGTCAGTTTGGCGCGGAGTTTGG CGGCCGGGGCTTACAGTGGCGGGAGTTGGAGGCGATAACGATTTGTGTTGTGAGAGGCGCAAGCTGCGATTTCTGCTGAACTTGGAGGCA TTTCTACGACTTTTCTCTCAGCTGAGGCTTTTCCTCCGACCCTGATGCTCTTCAATTCGGTGCTCCGCCAGCCCCAGCTTGGCGTCCTGA GAAATGGATGGTCTTCACAATACCCTCTTCAATCCCTTCTGACTGGTTATCAGTGCAGTGGTAATGATGAACACACTTCTTATGGAGAAA CAGGAGTCCCAGTTCCTCCTTTTGGATGTACCTTCTCTTCTGCTCCCAATATGGAACATGTACTAGCAGTTGCCAATGAAGAAGGCTTTG TTCGATTGTATAACACAGAATCACAAAGTTTCAGAAAGAAGTGCTTCAAAGAATGGATGGCTCACTGGAATGCCGTCTTTGACCTGGCCT GGGTTCCTGGTGAACTTAAACTTGTTACAGCAGCAGGTGATCAAACAGCCAAATTTTGGGACGTAAAAGCTGGTGAGCTGATTGGAACAT GCAAAGGTCATCAATGCAGCCTCAAGTCAGTTGCCTTTTCTAAGTTTGAGAAAGCTGTATTCTGTACGGGTGGAAGAGATGGCAACATTA TGGTCTGGGATACCAGGTGCAACAAAAAAGATGGGTTTTATAGGCAAGTGAATCAAATCAGTGGAGCTCACAATACCTCAGACAAGCAAA CCCCTTCAAAACCCAAGAAGAAACAGAATTCAAAAGGACTTGCTCCTTCTGTGGATTTCCAGCAAAGTGTTACTGTGGTCCTCTTTCAAG ACGAGAATACCTTAGTCTCAGCAGGAGCTGTGGATGGGATAATCAAAGTATGGGATTTACGTAAGAATTATACTGCTTATCGACAAGAAC CCATAGCATCCAAGTCTTTCCTGTACCCAGGTAGCAGCACTCGAAAACTTGGATATTCAAGTCTGATTTTGGATTCCACTGGCTCTACTT TATTTGCTAATTGCACAGACGATAACATCTACATGTTTAATATGACTGGGTTGAAGACTTCTCCAGTGGCTATTTTCAATGGACACCAGA ACTCTACCTTTTATGTAAAATCCAGCCTTAGTCCAGATGACCAGTTTTTAGTCAGTGGCTCAAGTGATGAAGCTGCCTACATATGGAAGG TCTCCACACCCTGGCAACCTCCTACTGTGCTCCTGGGTCATTCTCAAGAGGTCACGTCTGTGTGCTGGTGTCCATCTGACTTCACAAAGA TCAGTGCTAACATCTTCCGTACACTTCCTCCAAGTGATAATCCAGATTTTGATCCAGAAGAGGATGAACCCACGCTTGAGGCCTCTTGGC CTCACATACAGTTGGTATATGAATTCTTCTTGAGATTTTTGGAGAGCCCTGATTTCCAGCCTAGCATTGCAAAACGATACATTGATCAGA AATTCGTACAACAGCTCCTGGAGCTTTTTGATAGTGAAGATCCCAGAGAACGTGACTTCCTGAAGACTGTTCTGCACCGAATTTATGGGA AATTTCTTGGATTAAGAGCATTCATCAGAAAACAAATTAACAACATTTTCCTCAGGTTTATATATGAAACAGAACATTTCAATGGTGTTG CTGAACTTCTTGAAATATTAGGAAGTATTATCAATGGCTTTGCATTGCCACTGAAAGCAGAACATAAACAATTTCTAATGAAGGTTCTTA TTCCTATGCATACTGCAAAAGGATTAGCTTTGTTTCATGCTCAGCTAGCATATTGTGTTGTACAGTTCCTGGAGAAAGATACAACACTAA CAGAGCCAGTGATCAGAGGACTGCTGAAATTTTGGCCAAAAACCTGCAGTCAGAAAGAGGTGATGTTTTTAGGAGAAATTGAAGAAATCT TAGATGTCATTGAACCAACACAGTTCAAAAAAATTGAAGAGCCACTTTTCAAGCAGATATCCAAGTGTGTATCCAGTTCTCATTTTCAGG TTGCAGAAAGGGCATTGTACTTCTGGAATAACGAATATATTCTTAGTTTGATTGAGGAGAACATTGATAAAATTCTGCCAATTATGTTTG CCAGTTTGTACAAAATTTCCAAAGAACACTGGAATCCGACCATTGTAGCACTGGTATACAATGTGCTGAAAACCCTAATGGAAATGAATG GCAAGCTTTTCGATGACCTTACTAGCTCATACAAAGCTGAAAGACAGAGAGAGAAAAAGAAGGAATTGGAACGTGAAGAATTATGGAAAA AATTAGAGGAGCTAAAGCTAAAGAAAGCTCTAGAAAAACAGAATAGTGCTTACAACATGCACAGTATTCTCAGCAATACAAGTGCCGAAT AAAAAAAAAGCCTCCCACCTCTGCCGGATAGGCAGAGTTTTGTATGCTTTTTTGAAATATGTAAAAATTACAAAACAAACCTCATCAGTA TAATATAATTAAAAGGCCAATTTTTTCTGGCAACTGTAAATGGAAAAATATATGGACTAAACGTAGCCCTGTGCTGTATCATGGCCATAG TATATTGTAACCTTTGTCTAATCATTGGATTTATTGTGTCACTTCTGAAGTTTCACAGAAATGAATGAATTTTATCATCTATGATATGAG TGAGATAATTATGGGAGTGGTAAGAATTATGACTTGAATTCTTCTTTGATTGTGTTGCACATAGATATGGTAGTCTGCTCTGTATATTTT TCCCTTTTATAATGTGCTTTTCACACTGCTGCAAACCTTAGTTACATCCTAGGAAAAAATACTTCCTAAAATAAAACTAAGGTATCATCC TTACCCTTCTCTTTGTCTCACCCAGAAATATGATGGGGGGAATTACCTGCCCTAACCCCTCCCTCAATAAATACATTACTGTACTCTGGA ATTTAGGCAAAACCTTAAATCTCCAGGCTTTTTAAAGCACAAAATATAAATAAAAGCTGGGAAAGTAAACCAAAATTCTTCAGATTGTTC CTCATGAATATCCCCCTTCCTCTGCAATTCTCCAGAGTGGTAACAGATGGGTAGAGGCAGCTCAGGTGAATTACCCAGCTTGCCTCTCAA TTCATTCCTCCTCTTCCTCTCAAAGGCTGAAGGCAGGGCCTTTCCAGTCCTCACAACCTGTCCTTCACCTAGTCCCTCCTGACCCAGGGA TGGAGGCTTTGAGTCCCACAGTGTGGTGATACAGAGCACTAGTTGTCACTGCCTGGCTTTATTTAAAGGAACTGCAGTAGGCTTCCTCTG TAGAGCTCTGAAAAGGTTGACTATATAGAGGTCTTGTATGTTTTTACTTGGTCAAGTATTTCTCACATCTTTTGTTATCAGAGTACCATT CCAATCTCTTAACTTGCAGTTGTGTGGAAAACTGTTTTGTAATGAAAGATCTTCATTGGGGGATTGAGCAGCATTTAATAAAGTCTATGT >24356_24356_7_DTL-PPP2R5A_DTL_chr1_212251604_ENST00000366991_PPP2R5A_chr1_212506839_ENST00000261461_length(amino acids)=736AA_BP=1 MMLFNSVLRQPQLGVLRNGWSSQYPLQSLLTGYQCSGNDEHTSYGETGVPVPPFGCTFSSAPNMEHVLAVANEEGFVRLYNTESQSFRKK CFKEWMAHWNAVFDLAWVPGELKLVTAAGDQTAKFWDVKAGELIGTCKGHQCSLKSVAFSKFEKAVFCTGGRDGNIMVWDTRCNKKDGFY RQVNQISGAHNTSDKQTPSKPKKKQNSKGLAPSVDFQQSVTVVLFQDENTLVSAGAVDGIIKVWDLRKNYTAYRQEPIASKSFLYPGSST RKLGYSSLILDSTGSTLFANCTDDNIYMFNMTGLKTSPVAIFNGHQNSTFYVKSSLSPDDQFLVSGSSDEAAYIWKVSTPWQPPTVLLGH SQEVTSVCWCPSDFTKISANIFRTLPPSDNPDFDPEEDEPTLEASWPHIQLVYEFFLRFLESPDFQPSIAKRYIDQKFVQQLLELFDSED PRERDFLKTVLHRIYGKFLGLRAFIRKQINNIFLRFIYETEHFNGVAELLEILGSIINGFALPLKAEHKQFLMKVLIPMHTAKGLALFHA QLAYCVVQFLEKDTTLTEPVIRGLLKFWPKTCSQKEVMFLGEIEEILDVIEPTQFKKIEEPLFKQISKCVSSSHFQVAERALYFWNNEYI LSLIEENIDKILPIMFASLYKISKEHWNPTIVALVYNVLKTLMEMNGKLFDDLTSSYKAERQREKKKELEREELWKKLEELKLKKALEKQ -------------------------------------------------------------- >24356_24356_8_DTL-PPP2R5A_DTL_chr1_212251604_ENST00000366991_PPP2R5A_chr1_212506839_ENST00000537030_length(transcript)=2674nt_BP=1439nt CGCGGTTTGTCCGCGCCTCTGCTACCCCCTGCGCAGGCGCTCAAGGAGCTCTTGGACTCCAGGTTCCCGCGGCTGGGAGAAAAGGAGGCG GGGATCCGAAGGGGGAAATGACTCTGAGGCGCCCGGACGTCGCTCGGAAGCCAATCAGAGAGCGTGACGTCAGTTTGGCGCGGAGTTTGG CGGCCGGGGCTTACAGTGGCGGGAGTTGGAGGCGATAACGATTTGTGTTGTGAGAGGCGCAAGCTGCGATTTCTGCTGAACTTGGAGGCA TTTCTACGACTTTTCTCTCAGCTGAGGCTTTTCCTCCGACCCTGATGCTCTTCAATTCGGTGCTCCGCCAGCCCCAGCTTGGCGTCCTGA GAAATGGATGGTCTTCACAATACCCTCTTCAATCCCTTCTGACTGGTTATCAGTGCAGTGGTAATGATGAACACACTTCTTATGGAGAAA CAGGAGTCCCAGTTCCTCCTTTTGGATGTACCTTCTCTTCTGCTCCCAATATGGAACATGTACTAGCAGTTGCCAATGAAGAAGGCTTTG TTCGATTGTATAACACAGAATCACAAAGTTTCAGAAAGAAGTGCTTCAAAGAATGGATGGCTCACTGGAATGCCGTCTTTGACCTGGCCT GGGTTCCTGGTGAACTTAAACTTGTTACAGCAGCAGGTGATCAAACAGCCAAATTTTGGGACGTAAAAGCTGGTGAGCTGATTGGAACAT GCAAAGGTCATCAATGCAGCCTCAAGTCAGTTGCCTTTTCTAAGTTTGAGAAAGCTGTATTCTGTACGGGTGGAAGAGATGGCAACATTA TGGTCTGGGATACCAGGTGCAACAAAAAAGATGGGTTTTATAGGCAAGTGAATCAAATCAGTGGAGCTCACAATACCTCAGACAAGCAAA CCCCTTCAAAACCCAAGAAGAAACAGAATTCAAAAGGACTTGCTCCTTCTGTGGATTTCCAGCAAAGTGTTACTGTGGTCCTCTTTCAAG ACGAGAATACCTTAGTCTCAGCAGGAGCTGTGGATGGGATAATCAAAGTATGGGATTTACGTAAGAATTATACTGCTTATCGACAAGAAC CCATAGCATCCAAGTCTTTCCTGTACCCAGGTAGCAGCACTCGAAAACTTGGATATTCAAGTCTGATTTTGGATTCCACTGGCTCTACTT TATTTGCTAATTGCACAGACGATAACATCTACATGTTTAATATGACTGGGTTGAAGACTTCTCCAGTGGCTATTTTCAATGGACACCAGA ACTCTACCTTTTATGTAAAATCCAGCCTTAGTCCAGATGACCAGTTTTTAGTCAGTGGCTCAAGTGATGAAGCTGCCTACATATGGAAGG TCTCCACACCCTGGCAACCTCCTACTGTGCTCCTGGGTCATTCTCAAGAGGTCACGTCTGTGTGCTGGTGTCCATCTGACTTCACAAAGA TCAGTGCTAACATCTTCCGTACACTTCCTCCAAGTGATAATCCAGATTTTGATCCAGAAGAGGATGAACCCACGCTTGAGGCCTCTTGGC CTCACATACAGTTGGTATATGAATTCTTCTTGAGATTTTTGGAGAGCCCTGATTTCCAGCCTAGCATTGCAAAACGATACATTGATCAGA AATTCGTACAACAGCTCCTGGAGCTTTTTGATAGTGAAGATCCCAGAGAACGTGACTTCCTGAAGACTGTTCTGCACCGAATTTATGGGA AATTTCTTGGATTAAGAGCATTCATCAGAAAACAAATTAACAACATTTTCCTCAGGTTTATATATGAAACAGAACATTTCAATGGTGTTG CTGAACTTCTTGAAATATTAGGAAGTATTATCAATGGCTTTGCATTGCCACTGAAAGCAGAACATAAACAATTTCTAATGAAGGTTCTTA TTCCTATGCATACTGCAAAAGGATTAGCTTTGTTTCATGCTCAGCTAGCATATTGTGTTGTACAGTTCCTGGAGAAAGATACAACACTAA CAGAGCCAGTGATCAGAGGACTGCTGAAATTTTGGCCAAAAACCTGCAGTCAGAAAGAGGTGATGTTTTTAGGAGAAATTGAAGAAATCT TAGATGTCATTGAACCAACACAGTTCAAAAAAATTGAAGAGCCACTTTTCAAGCAGATATCCAAGTGTGTATCCAGTTCTCATTTTCAGG TTGCAGAAAGGGCATTGTACTTCTGGAATAACGAATATATTCTTAGTTTGATTGAGGAGAACATTGATAAAATTCTGCCAATTATGTTTG CCAGTTTGTACAAAATTTCCAAAGAACACTGGAATCCGACCATTGTAGCACTGGTATACAATGTGCTGAAAACCCTAATGGAAATGAATG GCAAGCTTTTCGATGACCTTACTAGCTCATACAAAGCTGAAAGACAGAGAGAGAAAAAGAAGGAATTGGAACGTGAAGAATTATGGAAAA AATTAGAGGAGCTAAAGCTAAAGAAAGCTCTAGAAAAACAGAATAGTGCTTACAACATGCACAGTATTCTCAGCAATACAAGTGCCGAAT AAAAAAAAAGCCTCCCACCTCTGCCGGATAGGCAGAGTTTTGTATGCTTTTTTGAAATATGTAAAAATTACAAAACAAACCTCATCAGTA >24356_24356_8_DTL-PPP2R5A_DTL_chr1_212251604_ENST00000366991_PPP2R5A_chr1_212506839_ENST00000537030_length(amino acids)=736AA_BP=1 MMLFNSVLRQPQLGVLRNGWSSQYPLQSLLTGYQCSGNDEHTSYGETGVPVPPFGCTFSSAPNMEHVLAVANEEGFVRLYNTESQSFRKK CFKEWMAHWNAVFDLAWVPGELKLVTAAGDQTAKFWDVKAGELIGTCKGHQCSLKSVAFSKFEKAVFCTGGRDGNIMVWDTRCNKKDGFY RQVNQISGAHNTSDKQTPSKPKKKQNSKGLAPSVDFQQSVTVVLFQDENTLVSAGAVDGIIKVWDLRKNYTAYRQEPIASKSFLYPGSST RKLGYSSLILDSTGSTLFANCTDDNIYMFNMTGLKTSPVAIFNGHQNSTFYVKSSLSPDDQFLVSGSSDEAAYIWKVSTPWQPPTVLLGH SQEVTSVCWCPSDFTKISANIFRTLPPSDNPDFDPEEDEPTLEASWPHIQLVYEFFLRFLESPDFQPSIAKRYIDQKFVQQLLELFDSED PRERDFLKTVLHRIYGKFLGLRAFIRKQINNIFLRFIYETEHFNGVAELLEILGSIINGFALPLKAEHKQFLMKVLIPMHTAKGLALFHA QLAYCVVQFLEKDTTLTEPVIRGLLKFWPKTCSQKEVMFLGEIEEILDVIEPTQFKKIEEPLFKQISKCVSSSHFQVAERALYFWNNEYI LSLIEENIDKILPIMFASLYKISKEHWNPTIVALVYNVLKTLMEMNGKLFDDLTSSYKAERQREKKKELEREELWKKLEELKLKKALEKQ -------------------------------------------------------------- >24356_24356_9_DTL-PPP2R5A_DTL_chr1_212251604_ENST00000542077_PPP2R5A_chr1_212506838_ENST00000261461_length(transcript)=3311nt_BP=1140nt AGTTTGGCGGCCGGGGCTTACAGTGGCGGGAGTTGGAGGCGATAACGATTTGTGTTGTGAGAGGCGCAAGCTGCGATTTCTGCTGAACTT GGAGGCATTTCTACGACTTTTCTCTCAGCTGAGGCTTTTCCTCCGACCCTGATGCTCTTCAATTCGGTGCTCCGCCAGCCCCAGCTTGGC GTCCTGAGAAATGCTCCCAATATGGAACATGTACTAGCAGTTGCCAATGAAGAAGGCTTTGTTCGATTGTATAACACAGAATCACAAAGT TTCAGAAAGAAGTGCTTCAAAGAATGGATGGCTCACTGGAATGCCGTCTTTGACCTGGCCTGGGTTCCTGGTGAACTTAAACTTGTTACA GCAGCAGGTGATCAAACAGCCAAATTTTGGGACGTAAAAGCTGGTGAGCTGATTGGAACATGCAAAGGTCATCAATGCAGCCTCAAGTCA GTTGCCTTTTCTAAGTTTGAGAAAGCTGTATTCTGTACGGGTGGAAGAGATGGCAACATTATGGTCTGGGATACCAGGTGCAACAAAAAA GATGGGTTTTATAGGCAAGTGAATCAAATCAGTGGAGCTCACAATACCTCAGACAAGCAAACCCCTTCAAAACCCAAGAAGAAACAGAAT TCAAAAGGACTTGCTCCTTCTGTGGATTTCCAGCAAAGTGTTACTGTGGTCCTCTTTCAAGACGAGAATACCTTAGTCTCAGCAGGAGCT GTGGATGGGATAATCAAAGTATGGGATTTACGTAAGAATTATACTGCTTATCGACAAGAACCCATAGCATCCAAGTCTTTCCTGTACCCA GGTAGCAGCACTCGAAAACTTGGATATTCAAGTCTGATTTTGGATTCCACTGGCTCTACTTTATTTGCTAATTGCACAGACGATAACATC TACATGTTTAATATGACTGGGTTGAAGACTTCTCCAGTGGCTATTTTCAATGGACACCAGAACTCTACCTTTTATGTAAAATCCAGCCTT AGTCCAGATGACCAGTTTTTAGTCAGTGGCTCAAGTGATGAAGCTGCCTACATATGGAAGGTCTCCACACCCTGGCAACCTCCTACTGTG CTCCTGGGTCATTCTCAAGAGGTCACGTCTGTGTGCTGGTGTCCATCTGACTTCACAAAGATCAGTGCTAACATCTTCCGTACACTTCCT CCAAGTGATAATCCAGATTTTGATCCAGAAGAGGATGAACCCACGCTTGAGGCCTCTTGGCCTCACATACAGTTGGTATATGAATTCTTC TTGAGATTTTTGGAGAGCCCTGATTTCCAGCCTAGCATTGCAAAACGATACATTGATCAGAAATTCGTACAACAGCTCCTGGAGCTTTTT GATAGTGAAGATCCCAGAGAACGTGACTTCCTGAAGACTGTTCTGCACCGAATTTATGGGAAATTTCTTGGATTAAGAGCATTCATCAGA AAACAAATTAACAACATTTTCCTCAGGTTTATATATGAAACAGAACATTTCAATGGTGTTGCTGAACTTCTTGAAATATTAGGAAGTATT ATCAATGGCTTTGCATTGCCACTGAAAGCAGAACATAAACAATTTCTAATGAAGGTTCTTATTCCTATGCATACTGCAAAAGGATTAGCT TTGTTTCATGCTCAGCTAGCATATTGTGTTGTACAGTTCCTGGAGAAAGATACAACACTAACAGAGCCAGTGATCAGAGGACTGCTGAAA TTTTGGCCAAAAACCTGCAGTCAGAAAGAGGTGATGTTTTTAGGAGAAATTGAAGAAATCTTAGATGTCATTGAACCAACACAGTTCAAA AAAATTGAAGAGCCACTTTTCAAGCAGATATCCAAGTGTGTATCCAGTTCTCATTTTCAGGTTGCAGAAAGGGCATTGTACTTCTGGAAT AACGAATATATTCTTAGTTTGATTGAGGAGAACATTGATAAAATTCTGCCAATTATGTTTGCCAGTTTGTACAAAATTTCCAAAGAACAC TGGAATCCGACCATTGTAGCACTGGTATACAATGTGCTGAAAACCCTAATGGAAATGAATGGCAAGCTTTTCGATGACCTTACTAGCTCA TACAAAGCTGAAAGACAGAGAGAGAAAAAGAAGGAATTGGAACGTGAAGAATTATGGAAAAAATTAGAGGAGCTAAAGCTAAAGAAAGCT CTAGAAAAACAGAATAGTGCTTACAACATGCACAGTATTCTCAGCAATACAAGTGCCGAATAAAAAAAAAGCCTCCCACCTCTGCCGGAT AGGCAGAGTTTTGTATGCTTTTTTGAAATATGTAAAAATTACAAAACAAACCTCATCAGTATAATATAATTAAAAGGCCAATTTTTTCTG GCAACTGTAAATGGAAAAATATATGGACTAAACGTAGCCCTGTGCTGTATCATGGCCATAGTATATTGTAACCTTTGTCTAATCATTGGA TTTATTGTGTCACTTCTGAAGTTTCACAGAAATGAATGAATTTTATCATCTATGATATGAGTGAGATAATTATGGGAGTGGTAAGAATTA TGACTTGAATTCTTCTTTGATTGTGTTGCACATAGATATGGTAGTCTGCTCTGTATATTTTTCCCTTTTATAATGTGCTTTTCACACTGC TGCAAACCTTAGTTACATCCTAGGAAAAAATACTTCCTAAAATAAAACTAAGGTATCATCCTTACCCTTCTCTTTGTCTCACCCAGAAAT ATGATGGGGGGAATTACCTGCCCTAACCCCTCCCTCAATAAATACATTACTGTACTCTGGAATTTAGGCAAAACCTTAAATCTCCAGGCT TTTTAAAGCACAAAATATAAATAAAAGCTGGGAAAGTAAACCAAAATTCTTCAGATTGTTCCTCATGAATATCCCCCTTCCTCTGCAATT CTCCAGAGTGGTAACAGATGGGTAGAGGCAGCTCAGGTGAATTACCCAGCTTGCCTCTCAATTCATTCCTCCTCTTCCTCTCAAAGGCTG AAGGCAGGGCCTTTCCAGTCCTCACAACCTGTCCTTCACCTAGTCCCTCCTGACCCAGGGATGGAGGCTTTGAGTCCCACAGTGTGGTGA TACAGAGCACTAGTTGTCACTGCCTGGCTTTATTTAAAGGAACTGCAGTAGGCTTCCTCTGTAGAGCTCTGAAAAGGTTGACTATATAGA GGTCTTGTATGTTTTTACTTGGTCAAGTATTTCTCACATCTTTTGTTATCAGAGTACCATTCCAATCTCTTAACTTGCAGTTGTGTGGAA >24356_24356_9_DTL-PPP2R5A_DTL_chr1_212251604_ENST00000542077_PPP2R5A_chr1_212506838_ENST00000261461_length(amino acids)=694AA_BP=1 MMLFNSVLRQPQLGVLRNAPNMEHVLAVANEEGFVRLYNTESQSFRKKCFKEWMAHWNAVFDLAWVPGELKLVTAAGDQTAKFWDVKAGE LIGTCKGHQCSLKSVAFSKFEKAVFCTGGRDGNIMVWDTRCNKKDGFYRQVNQISGAHNTSDKQTPSKPKKKQNSKGLAPSVDFQQSVTV VLFQDENTLVSAGAVDGIIKVWDLRKNYTAYRQEPIASKSFLYPGSSTRKLGYSSLILDSTGSTLFANCTDDNIYMFNMTGLKTSPVAIF NGHQNSTFYVKSSLSPDDQFLVSGSSDEAAYIWKVSTPWQPPTVLLGHSQEVTSVCWCPSDFTKISANIFRTLPPSDNPDFDPEEDEPTL EASWPHIQLVYEFFLRFLESPDFQPSIAKRYIDQKFVQQLLELFDSEDPRERDFLKTVLHRIYGKFLGLRAFIRKQINNIFLRFIYETEH FNGVAELLEILGSIINGFALPLKAEHKQFLMKVLIPMHTAKGLALFHAQLAYCVVQFLEKDTTLTEPVIRGLLKFWPKTCSQKEVMFLGE IEEILDVIEPTQFKKIEEPLFKQISKCVSSSHFQVAERALYFWNNEYILSLIEENIDKILPIMFASLYKISKEHWNPTIVALVYNVLKTL -------------------------------------------------------------- >24356_24356_10_DTL-PPP2R5A_DTL_chr1_212251604_ENST00000542077_PPP2R5A_chr1_212506838_ENST00000537030_length(transcript)=2375nt_BP=1140nt AGTTTGGCGGCCGGGGCTTACAGTGGCGGGAGTTGGAGGCGATAACGATTTGTGTTGTGAGAGGCGCAAGCTGCGATTTCTGCTGAACTT GGAGGCATTTCTACGACTTTTCTCTCAGCTGAGGCTTTTCCTCCGACCCTGATGCTCTTCAATTCGGTGCTCCGCCAGCCCCAGCTTGGC GTCCTGAGAAATGCTCCCAATATGGAACATGTACTAGCAGTTGCCAATGAAGAAGGCTTTGTTCGATTGTATAACACAGAATCACAAAGT TTCAGAAAGAAGTGCTTCAAAGAATGGATGGCTCACTGGAATGCCGTCTTTGACCTGGCCTGGGTTCCTGGTGAACTTAAACTTGTTACA GCAGCAGGTGATCAAACAGCCAAATTTTGGGACGTAAAAGCTGGTGAGCTGATTGGAACATGCAAAGGTCATCAATGCAGCCTCAAGTCA GTTGCCTTTTCTAAGTTTGAGAAAGCTGTATTCTGTACGGGTGGAAGAGATGGCAACATTATGGTCTGGGATACCAGGTGCAACAAAAAA GATGGGTTTTATAGGCAAGTGAATCAAATCAGTGGAGCTCACAATACCTCAGACAAGCAAACCCCTTCAAAACCCAAGAAGAAACAGAAT TCAAAAGGACTTGCTCCTTCTGTGGATTTCCAGCAAAGTGTTACTGTGGTCCTCTTTCAAGACGAGAATACCTTAGTCTCAGCAGGAGCT GTGGATGGGATAATCAAAGTATGGGATTTACGTAAGAATTATACTGCTTATCGACAAGAACCCATAGCATCCAAGTCTTTCCTGTACCCA GGTAGCAGCACTCGAAAACTTGGATATTCAAGTCTGATTTTGGATTCCACTGGCTCTACTTTATTTGCTAATTGCACAGACGATAACATC TACATGTTTAATATGACTGGGTTGAAGACTTCTCCAGTGGCTATTTTCAATGGACACCAGAACTCTACCTTTTATGTAAAATCCAGCCTT AGTCCAGATGACCAGTTTTTAGTCAGTGGCTCAAGTGATGAAGCTGCCTACATATGGAAGGTCTCCACACCCTGGCAACCTCCTACTGTG CTCCTGGGTCATTCTCAAGAGGTCACGTCTGTGTGCTGGTGTCCATCTGACTTCACAAAGATCAGTGCTAACATCTTCCGTACACTTCCT CCAAGTGATAATCCAGATTTTGATCCAGAAGAGGATGAACCCACGCTTGAGGCCTCTTGGCCTCACATACAGTTGGTATATGAATTCTTC TTGAGATTTTTGGAGAGCCCTGATTTCCAGCCTAGCATTGCAAAACGATACATTGATCAGAAATTCGTACAACAGCTCCTGGAGCTTTTT GATAGTGAAGATCCCAGAGAACGTGACTTCCTGAAGACTGTTCTGCACCGAATTTATGGGAAATTTCTTGGATTAAGAGCATTCATCAGA AAACAAATTAACAACATTTTCCTCAGGTTTATATATGAAACAGAACATTTCAATGGTGTTGCTGAACTTCTTGAAATATTAGGAAGTATT ATCAATGGCTTTGCATTGCCACTGAAAGCAGAACATAAACAATTTCTAATGAAGGTTCTTATTCCTATGCATACTGCAAAAGGATTAGCT TTGTTTCATGCTCAGCTAGCATATTGTGTTGTACAGTTCCTGGAGAAAGATACAACACTAACAGAGCCAGTGATCAGAGGACTGCTGAAA TTTTGGCCAAAAACCTGCAGTCAGAAAGAGGTGATGTTTTTAGGAGAAATTGAAGAAATCTTAGATGTCATTGAACCAACACAGTTCAAA AAAATTGAAGAGCCACTTTTCAAGCAGATATCCAAGTGTGTATCCAGTTCTCATTTTCAGGTTGCAGAAAGGGCATTGTACTTCTGGAAT AACGAATATATTCTTAGTTTGATTGAGGAGAACATTGATAAAATTCTGCCAATTATGTTTGCCAGTTTGTACAAAATTTCCAAAGAACAC TGGAATCCGACCATTGTAGCACTGGTATACAATGTGCTGAAAACCCTAATGGAAATGAATGGCAAGCTTTTCGATGACCTTACTAGCTCA TACAAAGCTGAAAGACAGAGAGAGAAAAAGAAGGAATTGGAACGTGAAGAATTATGGAAAAAATTAGAGGAGCTAAAGCTAAAGAAAGCT CTAGAAAAACAGAATAGTGCTTACAACATGCACAGTATTCTCAGCAATACAAGTGCCGAATAAAAAAAAAGCCTCCCACCTCTGCCGGAT AGGCAGAGTTTTGTATGCTTTTTTGAAATATGTAAAAATTACAAAACAAACCTCATCAGTATAATATAATTAAAAGGCCAATTTTTTCTG >24356_24356_10_DTL-PPP2R5A_DTL_chr1_212251604_ENST00000542077_PPP2R5A_chr1_212506838_ENST00000537030_length(amino acids)=694AA_BP=1 MMLFNSVLRQPQLGVLRNAPNMEHVLAVANEEGFVRLYNTESQSFRKKCFKEWMAHWNAVFDLAWVPGELKLVTAAGDQTAKFWDVKAGE LIGTCKGHQCSLKSVAFSKFEKAVFCTGGRDGNIMVWDTRCNKKDGFYRQVNQISGAHNTSDKQTPSKPKKKQNSKGLAPSVDFQQSVTV VLFQDENTLVSAGAVDGIIKVWDLRKNYTAYRQEPIASKSFLYPGSSTRKLGYSSLILDSTGSTLFANCTDDNIYMFNMTGLKTSPVAIF NGHQNSTFYVKSSLSPDDQFLVSGSSDEAAYIWKVSTPWQPPTVLLGHSQEVTSVCWCPSDFTKISANIFRTLPPSDNPDFDPEEDEPTL EASWPHIQLVYEFFLRFLESPDFQPSIAKRYIDQKFVQQLLELFDSEDPRERDFLKTVLHRIYGKFLGLRAFIRKQINNIFLRFIYETEH FNGVAELLEILGSIINGFALPLKAEHKQFLMKVLIPMHTAKGLALFHAQLAYCVVQFLEKDTTLTEPVIRGLLKFWPKTCSQKEVMFLGE IEEILDVIEPTQFKKIEEPLFKQISKCVSSSHFQVAERALYFWNNEYILSLIEENIDKILPIMFASLYKISKEHWNPTIVALVYNVLKTL -------------------------------------------------------------- >24356_24356_11_DTL-PPP2R5A_DTL_chr1_212251604_ENST00000542077_PPP2R5A_chr1_212506839_ENST00000261461_length(transcript)=3311nt_BP=1140nt AGTTTGGCGGCCGGGGCTTACAGTGGCGGGAGTTGGAGGCGATAACGATTTGTGTTGTGAGAGGCGCAAGCTGCGATTTCTGCTGAACTT GGAGGCATTTCTACGACTTTTCTCTCAGCTGAGGCTTTTCCTCCGACCCTGATGCTCTTCAATTCGGTGCTCCGCCAGCCCCAGCTTGGC GTCCTGAGAAATGCTCCCAATATGGAACATGTACTAGCAGTTGCCAATGAAGAAGGCTTTGTTCGATTGTATAACACAGAATCACAAAGT TTCAGAAAGAAGTGCTTCAAAGAATGGATGGCTCACTGGAATGCCGTCTTTGACCTGGCCTGGGTTCCTGGTGAACTTAAACTTGTTACA GCAGCAGGTGATCAAACAGCCAAATTTTGGGACGTAAAAGCTGGTGAGCTGATTGGAACATGCAAAGGTCATCAATGCAGCCTCAAGTCA GTTGCCTTTTCTAAGTTTGAGAAAGCTGTATTCTGTACGGGTGGAAGAGATGGCAACATTATGGTCTGGGATACCAGGTGCAACAAAAAA GATGGGTTTTATAGGCAAGTGAATCAAATCAGTGGAGCTCACAATACCTCAGACAAGCAAACCCCTTCAAAACCCAAGAAGAAACAGAAT TCAAAAGGACTTGCTCCTTCTGTGGATTTCCAGCAAAGTGTTACTGTGGTCCTCTTTCAAGACGAGAATACCTTAGTCTCAGCAGGAGCT GTGGATGGGATAATCAAAGTATGGGATTTACGTAAGAATTATACTGCTTATCGACAAGAACCCATAGCATCCAAGTCTTTCCTGTACCCA GGTAGCAGCACTCGAAAACTTGGATATTCAAGTCTGATTTTGGATTCCACTGGCTCTACTTTATTTGCTAATTGCACAGACGATAACATC TACATGTTTAATATGACTGGGTTGAAGACTTCTCCAGTGGCTATTTTCAATGGACACCAGAACTCTACCTTTTATGTAAAATCCAGCCTT AGTCCAGATGACCAGTTTTTAGTCAGTGGCTCAAGTGATGAAGCTGCCTACATATGGAAGGTCTCCACACCCTGGCAACCTCCTACTGTG CTCCTGGGTCATTCTCAAGAGGTCACGTCTGTGTGCTGGTGTCCATCTGACTTCACAAAGATCAGTGCTAACATCTTCCGTACACTTCCT CCAAGTGATAATCCAGATTTTGATCCAGAAGAGGATGAACCCACGCTTGAGGCCTCTTGGCCTCACATACAGTTGGTATATGAATTCTTC TTGAGATTTTTGGAGAGCCCTGATTTCCAGCCTAGCATTGCAAAACGATACATTGATCAGAAATTCGTACAACAGCTCCTGGAGCTTTTT GATAGTGAAGATCCCAGAGAACGTGACTTCCTGAAGACTGTTCTGCACCGAATTTATGGGAAATTTCTTGGATTAAGAGCATTCATCAGA AAACAAATTAACAACATTTTCCTCAGGTTTATATATGAAACAGAACATTTCAATGGTGTTGCTGAACTTCTTGAAATATTAGGAAGTATT ATCAATGGCTTTGCATTGCCACTGAAAGCAGAACATAAACAATTTCTAATGAAGGTTCTTATTCCTATGCATACTGCAAAAGGATTAGCT TTGTTTCATGCTCAGCTAGCATATTGTGTTGTACAGTTCCTGGAGAAAGATACAACACTAACAGAGCCAGTGATCAGAGGACTGCTGAAA TTTTGGCCAAAAACCTGCAGTCAGAAAGAGGTGATGTTTTTAGGAGAAATTGAAGAAATCTTAGATGTCATTGAACCAACACAGTTCAAA AAAATTGAAGAGCCACTTTTCAAGCAGATATCCAAGTGTGTATCCAGTTCTCATTTTCAGGTTGCAGAAAGGGCATTGTACTTCTGGAAT AACGAATATATTCTTAGTTTGATTGAGGAGAACATTGATAAAATTCTGCCAATTATGTTTGCCAGTTTGTACAAAATTTCCAAAGAACAC TGGAATCCGACCATTGTAGCACTGGTATACAATGTGCTGAAAACCCTAATGGAAATGAATGGCAAGCTTTTCGATGACCTTACTAGCTCA TACAAAGCTGAAAGACAGAGAGAGAAAAAGAAGGAATTGGAACGTGAAGAATTATGGAAAAAATTAGAGGAGCTAAAGCTAAAGAAAGCT CTAGAAAAACAGAATAGTGCTTACAACATGCACAGTATTCTCAGCAATACAAGTGCCGAATAAAAAAAAAGCCTCCCACCTCTGCCGGAT AGGCAGAGTTTTGTATGCTTTTTTGAAATATGTAAAAATTACAAAACAAACCTCATCAGTATAATATAATTAAAAGGCCAATTTTTTCTG GCAACTGTAAATGGAAAAATATATGGACTAAACGTAGCCCTGTGCTGTATCATGGCCATAGTATATTGTAACCTTTGTCTAATCATTGGA TTTATTGTGTCACTTCTGAAGTTTCACAGAAATGAATGAATTTTATCATCTATGATATGAGTGAGATAATTATGGGAGTGGTAAGAATTA TGACTTGAATTCTTCTTTGATTGTGTTGCACATAGATATGGTAGTCTGCTCTGTATATTTTTCCCTTTTATAATGTGCTTTTCACACTGC TGCAAACCTTAGTTACATCCTAGGAAAAAATACTTCCTAAAATAAAACTAAGGTATCATCCTTACCCTTCTCTTTGTCTCACCCAGAAAT ATGATGGGGGGAATTACCTGCCCTAACCCCTCCCTCAATAAATACATTACTGTACTCTGGAATTTAGGCAAAACCTTAAATCTCCAGGCT TTTTAAAGCACAAAATATAAATAAAAGCTGGGAAAGTAAACCAAAATTCTTCAGATTGTTCCTCATGAATATCCCCCTTCCTCTGCAATT CTCCAGAGTGGTAACAGATGGGTAGAGGCAGCTCAGGTGAATTACCCAGCTTGCCTCTCAATTCATTCCTCCTCTTCCTCTCAAAGGCTG AAGGCAGGGCCTTTCCAGTCCTCACAACCTGTCCTTCACCTAGTCCCTCCTGACCCAGGGATGGAGGCTTTGAGTCCCACAGTGTGGTGA TACAGAGCACTAGTTGTCACTGCCTGGCTTTATTTAAAGGAACTGCAGTAGGCTTCCTCTGTAGAGCTCTGAAAAGGTTGACTATATAGA GGTCTTGTATGTTTTTACTTGGTCAAGTATTTCTCACATCTTTTGTTATCAGAGTACCATTCCAATCTCTTAACTTGCAGTTGTGTGGAA >24356_24356_11_DTL-PPP2R5A_DTL_chr1_212251604_ENST00000542077_PPP2R5A_chr1_212506839_ENST00000261461_length(amino acids)=694AA_BP=1 MMLFNSVLRQPQLGVLRNAPNMEHVLAVANEEGFVRLYNTESQSFRKKCFKEWMAHWNAVFDLAWVPGELKLVTAAGDQTAKFWDVKAGE LIGTCKGHQCSLKSVAFSKFEKAVFCTGGRDGNIMVWDTRCNKKDGFYRQVNQISGAHNTSDKQTPSKPKKKQNSKGLAPSVDFQQSVTV VLFQDENTLVSAGAVDGIIKVWDLRKNYTAYRQEPIASKSFLYPGSSTRKLGYSSLILDSTGSTLFANCTDDNIYMFNMTGLKTSPVAIF NGHQNSTFYVKSSLSPDDQFLVSGSSDEAAYIWKVSTPWQPPTVLLGHSQEVTSVCWCPSDFTKISANIFRTLPPSDNPDFDPEEDEPTL EASWPHIQLVYEFFLRFLESPDFQPSIAKRYIDQKFVQQLLELFDSEDPRERDFLKTVLHRIYGKFLGLRAFIRKQINNIFLRFIYETEH FNGVAELLEILGSIINGFALPLKAEHKQFLMKVLIPMHTAKGLALFHAQLAYCVVQFLEKDTTLTEPVIRGLLKFWPKTCSQKEVMFLGE IEEILDVIEPTQFKKIEEPLFKQISKCVSSSHFQVAERALYFWNNEYILSLIEENIDKILPIMFASLYKISKEHWNPTIVALVYNVLKTL -------------------------------------------------------------- >24356_24356_12_DTL-PPP2R5A_DTL_chr1_212251604_ENST00000542077_PPP2R5A_chr1_212506839_ENST00000537030_length(transcript)=2375nt_BP=1140nt AGTTTGGCGGCCGGGGCTTACAGTGGCGGGAGTTGGAGGCGATAACGATTTGTGTTGTGAGAGGCGCAAGCTGCGATTTCTGCTGAACTT GGAGGCATTTCTACGACTTTTCTCTCAGCTGAGGCTTTTCCTCCGACCCTGATGCTCTTCAATTCGGTGCTCCGCCAGCCCCAGCTTGGC GTCCTGAGAAATGCTCCCAATATGGAACATGTACTAGCAGTTGCCAATGAAGAAGGCTTTGTTCGATTGTATAACACAGAATCACAAAGT TTCAGAAAGAAGTGCTTCAAAGAATGGATGGCTCACTGGAATGCCGTCTTTGACCTGGCCTGGGTTCCTGGTGAACTTAAACTTGTTACA GCAGCAGGTGATCAAACAGCCAAATTTTGGGACGTAAAAGCTGGTGAGCTGATTGGAACATGCAAAGGTCATCAATGCAGCCTCAAGTCA GTTGCCTTTTCTAAGTTTGAGAAAGCTGTATTCTGTACGGGTGGAAGAGATGGCAACATTATGGTCTGGGATACCAGGTGCAACAAAAAA GATGGGTTTTATAGGCAAGTGAATCAAATCAGTGGAGCTCACAATACCTCAGACAAGCAAACCCCTTCAAAACCCAAGAAGAAACAGAAT TCAAAAGGACTTGCTCCTTCTGTGGATTTCCAGCAAAGTGTTACTGTGGTCCTCTTTCAAGACGAGAATACCTTAGTCTCAGCAGGAGCT GTGGATGGGATAATCAAAGTATGGGATTTACGTAAGAATTATACTGCTTATCGACAAGAACCCATAGCATCCAAGTCTTTCCTGTACCCA GGTAGCAGCACTCGAAAACTTGGATATTCAAGTCTGATTTTGGATTCCACTGGCTCTACTTTATTTGCTAATTGCACAGACGATAACATC TACATGTTTAATATGACTGGGTTGAAGACTTCTCCAGTGGCTATTTTCAATGGACACCAGAACTCTACCTTTTATGTAAAATCCAGCCTT AGTCCAGATGACCAGTTTTTAGTCAGTGGCTCAAGTGATGAAGCTGCCTACATATGGAAGGTCTCCACACCCTGGCAACCTCCTACTGTG CTCCTGGGTCATTCTCAAGAGGTCACGTCTGTGTGCTGGTGTCCATCTGACTTCACAAAGATCAGTGCTAACATCTTCCGTACACTTCCT CCAAGTGATAATCCAGATTTTGATCCAGAAGAGGATGAACCCACGCTTGAGGCCTCTTGGCCTCACATACAGTTGGTATATGAATTCTTC TTGAGATTTTTGGAGAGCCCTGATTTCCAGCCTAGCATTGCAAAACGATACATTGATCAGAAATTCGTACAACAGCTCCTGGAGCTTTTT GATAGTGAAGATCCCAGAGAACGTGACTTCCTGAAGACTGTTCTGCACCGAATTTATGGGAAATTTCTTGGATTAAGAGCATTCATCAGA AAACAAATTAACAACATTTTCCTCAGGTTTATATATGAAACAGAACATTTCAATGGTGTTGCTGAACTTCTTGAAATATTAGGAAGTATT ATCAATGGCTTTGCATTGCCACTGAAAGCAGAACATAAACAATTTCTAATGAAGGTTCTTATTCCTATGCATACTGCAAAAGGATTAGCT TTGTTTCATGCTCAGCTAGCATATTGTGTTGTACAGTTCCTGGAGAAAGATACAACACTAACAGAGCCAGTGATCAGAGGACTGCTGAAA TTTTGGCCAAAAACCTGCAGTCAGAAAGAGGTGATGTTTTTAGGAGAAATTGAAGAAATCTTAGATGTCATTGAACCAACACAGTTCAAA AAAATTGAAGAGCCACTTTTCAAGCAGATATCCAAGTGTGTATCCAGTTCTCATTTTCAGGTTGCAGAAAGGGCATTGTACTTCTGGAAT AACGAATATATTCTTAGTTTGATTGAGGAGAACATTGATAAAATTCTGCCAATTATGTTTGCCAGTTTGTACAAAATTTCCAAAGAACAC TGGAATCCGACCATTGTAGCACTGGTATACAATGTGCTGAAAACCCTAATGGAAATGAATGGCAAGCTTTTCGATGACCTTACTAGCTCA TACAAAGCTGAAAGACAGAGAGAGAAAAAGAAGGAATTGGAACGTGAAGAATTATGGAAAAAATTAGAGGAGCTAAAGCTAAAGAAAGCT CTAGAAAAACAGAATAGTGCTTACAACATGCACAGTATTCTCAGCAATACAAGTGCCGAATAAAAAAAAAGCCTCCCACCTCTGCCGGAT AGGCAGAGTTTTGTATGCTTTTTTGAAATATGTAAAAATTACAAAACAAACCTCATCAGTATAATATAATTAAAAGGCCAATTTTTTCTG >24356_24356_12_DTL-PPP2R5A_DTL_chr1_212251604_ENST00000542077_PPP2R5A_chr1_212506839_ENST00000537030_length(amino acids)=694AA_BP=1 MMLFNSVLRQPQLGVLRNAPNMEHVLAVANEEGFVRLYNTESQSFRKKCFKEWMAHWNAVFDLAWVPGELKLVTAAGDQTAKFWDVKAGE LIGTCKGHQCSLKSVAFSKFEKAVFCTGGRDGNIMVWDTRCNKKDGFYRQVNQISGAHNTSDKQTPSKPKKKQNSKGLAPSVDFQQSVTV VLFQDENTLVSAGAVDGIIKVWDLRKNYTAYRQEPIASKSFLYPGSSTRKLGYSSLILDSTGSTLFANCTDDNIYMFNMTGLKTSPVAIF NGHQNSTFYVKSSLSPDDQFLVSGSSDEAAYIWKVSTPWQPPTVLLGHSQEVTSVCWCPSDFTKISANIFRTLPPSDNPDFDPEEDEPTL EASWPHIQLVYEFFLRFLESPDFQPSIAKRYIDQKFVQQLLELFDSEDPRERDFLKTVLHRIYGKFLGLRAFIRKQINNIFLRFIYETEH FNGVAELLEILGSIINGFALPLKAEHKQFLMKVLIPMHTAKGLALFHAQLAYCVVQFLEKDTTLTEPVIRGLLKFWPKTCSQKEVMFLGE IEEILDVIEPTQFKKIEEPLFKQISKCVSSSHFQVAERALYFWNNEYILSLIEENIDKILPIMFASLYKISKEHWNPTIVALVYNVLKTL -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for DTL-PPP2R5A |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for DTL-PPP2R5A |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for DTL-PPP2R5A |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | DTL | C0010606 | Adenoid Cystic Carcinoma | 1 | CTD_human |
| Hgene | DTL | C0036095 | Salivary Gland Neoplasms | 1 | CTD_human |
| Hgene | DTL | C0220636 | Malignant neoplasm of salivary gland | 1 | CTD_human |
| Hgene | DTL | C2239176 | Liver carcinoma | 1 | CTD_human |
| Tgene | C0013990 | Pathological accumulation of air in tissues | 1 | CTD_human |
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