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Fusion Gene Summary | |
Fusion Gene ORF analysis | |
Fusion Genomic Features | |
Fusion Protein Features | |
Fusion Gene Sequence | |
Fusion Gene PPI analysis | |
Related Drugs | |
Related Diseases |
Fusion gene:ACSL5-PPP1R13B (FusionGDB2 ID:HG51703TG23368) |
Fusion Gene Summary for ACSL5-PPP1R13B |
Fusion gene summary |
Fusion gene information | Fusion gene name: ACSL5-PPP1R13B | Fusion gene ID: hg51703tg23368 | Hgene | Tgene | Gene symbol | ACSL5 | PPP1R13B | Gene ID | 51703 | 23368 |
Gene name | acyl-CoA synthetase long chain family member 5 | protein phosphatase 1 regulatory subunit 13B | |
Synonyms | ACS2|ACS5|FACL5 | ASPP1|p53BP2-like|p85 | |
Cytomap | ('ACSL5')('PPP1R13B') 10q25.2 | 14q32.33 | |
Type of gene | protein-coding | protein-coding | |
Description | long-chain-fatty-acid--CoA ligase 5FACL5 for fatty acid coenzyme A ligase 5LACS 5arachidonate--CoA ligasefatty acid coenzyme A ligase 5fatty-acid-Coenzyme A ligase, long-chain 5long-chain acyl-CoA synthetase 5long-chain fatty acid coenzyme A ligase | apoptosis-stimulating of p53 protein 1apoptosis-stimulating protein of p53, 1protein phosphatase 1, regulatory (inhibitor) subunit 13B | |
Modification date | 20200313 | 20200313 | |
UniProtAcc | Q9ULC5 | . | |
Ensembl transtripts involved in fusion gene | ENST00000354273, ENST00000354655, ENST00000356116, ENST00000369410, ENST00000393081, ENST00000433418, ENST00000479936, | ||
Fusion gene scores | * DoF score | 6 X 6 X 5=180 | 10 X 10 X 5=500 |
# samples | 6 | 10 | |
** MAII score | log2(6/180*10)=-1.58496250072116 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(10/500*10)=-2.32192809488736 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
Context | PubMed: ACSL5 [Title/Abstract] AND PPP1R13B [Title/Abstract] AND fusion [Title/Abstract] | ||
Most frequent breakpoint | ACSL5(114186117)-PPP1R13B(104212890), # samples:1 | ||
Anticipated loss of major functional domain due to fusion event. | ACSL5-PPP1R13B seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. ACSL5-PPP1R13B seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. ACSL5-PPP1R13B seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. ACSL5-PPP1R13B seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. |
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
Partner | Gene | GO ID | GO term | PubMed ID |
Hgene | ACSL5 | GO:0001676 | long-chain fatty acid metabolic process | 24269233 |
Tgene | PPP1R13B | GO:0072332 | intrinsic apoptotic signaling pathway by p53 class mediator | 11684014 |
Fusion gene breakpoints across ACSL5 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
Fusion gene breakpoints across PPP1R13B (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
Fusion gene information * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
ChimerDB4 | STAD | TCGA-D7-A4Z0-01A | ACSL5 | chr10 | 114186117 | + | PPP1R13B | chr14 | 104212890 | - |
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Fusion Gene ORF analysis for ACSL5-PPP1R13B |
Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
5CDS-intron | ENST00000354273 | ENST00000423488 | ACSL5 | chr10 | 114186117 | + | PPP1R13B | chr14 | 104212890 | - |
5CDS-intron | ENST00000354273 | ENST00000555391 | ACSL5 | chr10 | 114186117 | + | PPP1R13B | chr14 | 104212890 | - |
5CDS-intron | ENST00000354655 | ENST00000423488 | ACSL5 | chr10 | 114186117 | + | PPP1R13B | chr14 | 104212890 | - |
5CDS-intron | ENST00000354655 | ENST00000555391 | ACSL5 | chr10 | 114186117 | + | PPP1R13B | chr14 | 104212890 | - |
5CDS-intron | ENST00000356116 | ENST00000423488 | ACSL5 | chr10 | 114186117 | + | PPP1R13B | chr14 | 104212890 | - |
5CDS-intron | ENST00000356116 | ENST00000555391 | ACSL5 | chr10 | 114186117 | + | PPP1R13B | chr14 | 104212890 | - |
5CDS-intron | ENST00000369410 | ENST00000423488 | ACSL5 | chr10 | 114186117 | + | PPP1R13B | chr14 | 104212890 | - |
5CDS-intron | ENST00000369410 | ENST00000555391 | ACSL5 | chr10 | 114186117 | + | PPP1R13B | chr14 | 104212890 | - |
5CDS-intron | ENST00000393081 | ENST00000423488 | ACSL5 | chr10 | 114186117 | + | PPP1R13B | chr14 | 104212890 | - |
5CDS-intron | ENST00000393081 | ENST00000555391 | ACSL5 | chr10 | 114186117 | + | PPP1R13B | chr14 | 104212890 | - |
5CDS-intron | ENST00000433418 | ENST00000423488 | ACSL5 | chr10 | 114186117 | + | PPP1R13B | chr14 | 104212890 | - |
5CDS-intron | ENST00000433418 | ENST00000555391 | ACSL5 | chr10 | 114186117 | + | PPP1R13B | chr14 | 104212890 | - |
In-frame | ENST00000354273 | ENST00000202556 | ACSL5 | chr10 | 114186117 | + | PPP1R13B | chr14 | 104212890 | - |
In-frame | ENST00000354655 | ENST00000202556 | ACSL5 | chr10 | 114186117 | + | PPP1R13B | chr14 | 104212890 | - |
In-frame | ENST00000356116 | ENST00000202556 | ACSL5 | chr10 | 114186117 | + | PPP1R13B | chr14 | 104212890 | - |
In-frame | ENST00000369410 | ENST00000202556 | ACSL5 | chr10 | 114186117 | + | PPP1R13B | chr14 | 104212890 | - |
In-frame | ENST00000393081 | ENST00000202556 | ACSL5 | chr10 | 114186117 | + | PPP1R13B | chr14 | 104212890 | - |
In-frame | ENST00000433418 | ENST00000202556 | ACSL5 | chr10 | 114186117 | + | PPP1R13B | chr14 | 104212890 | - |
intron-3CDS | ENST00000479936 | ENST00000202556 | ACSL5 | chr10 | 114186117 | + | PPP1R13B | chr14 | 104212890 | - |
intron-intron | ENST00000479936 | ENST00000423488 | ACSL5 | chr10 | 114186117 | + | PPP1R13B | chr14 | 104212890 | - |
intron-intron | ENST00000479936 | ENST00000555391 | ACSL5 | chr10 | 114186117 | + | PPP1R13B | chr14 | 104212890 | - |
ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
ENST00000354655 | ACSL5 | chr10 | 114186117 | + | ENST00000202556 | PPP1R13B | chr14 | 104212890 | - | 5826 | 2120 | 254 | 4423 | 1389 |
ENST00000393081 | ACSL5 | chr10 | 114186117 | + | ENST00000202556 | PPP1R13B | chr14 | 104212890 | - | 5852 | 2146 | 280 | 4449 | 1389 |
ENST00000433418 | ACSL5 | chr10 | 114186117 | + | ENST00000202556 | PPP1R13B | chr14 | 104212890 | - | 5825 | 2119 | 49 | 4422 | 1457 |
ENST00000356116 | ACSL5 | chr10 | 114186117 | + | ENST00000202556 | PPP1R13B | chr14 | 104212890 | - | 5825 | 2119 | 49 | 4422 | 1457 |
ENST00000354273 | ACSL5 | chr10 | 114186117 | + | ENST00000202556 | PPP1R13B | chr14 | 104212890 | - | 5824 | 2118 | 48 | 4421 | 1457 |
ENST00000369410 | ACSL5 | chr10 | 114186117 | + | ENST00000202556 | PPP1R13B | chr14 | 104212890 | - | 5055 | 1349 | 164 | 3652 | 1162 |
DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
ENST00000354655 | ENST00000202556 | ACSL5 | chr10 | 114186117 | + | PPP1R13B | chr14 | 104212890 | - | 0.000899156 | 0.9991009 |
ENST00000393081 | ENST00000202556 | ACSL5 | chr10 | 114186117 | + | PPP1R13B | chr14 | 104212890 | - | 0.001154624 | 0.99884534 |
ENST00000433418 | ENST00000202556 | ACSL5 | chr10 | 114186117 | + | PPP1R13B | chr14 | 104212890 | - | 0.001020902 | 0.9989791 |
ENST00000356116 | ENST00000202556 | ACSL5 | chr10 | 114186117 | + | PPP1R13B | chr14 | 104212890 | - | 0.001020902 | 0.9989791 |
ENST00000354273 | ENST00000202556 | ACSL5 | chr10 | 114186117 | + | PPP1R13B | chr14 | 104212890 | - | 0.001026765 | 0.99897325 |
ENST00000369410 | ENST00000202556 | ACSL5 | chr10 | 114186117 | + | PPP1R13B | chr14 | 104212890 | - | 0.001052688 | 0.9989473 |
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Fusion Genomic Features for ACSL5-PPP1R13B |
FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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Fusion Protein Features for ACSL5-PPP1R13B |
Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr10:114186117/chr14:104212890) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
Main function of each fusion partner protein. (from UniProt) |
Hgene | Tgene |
ACSL5 | . |
FUNCTION: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation (PubMed:17681178, PubMed:24269233, PubMed:22633490). ACSL5 may activate fatty acids from exogenous sources for the synthesis of triacylglycerol destined for intracellular storage (By similarity). Utilizes a wide range of saturated fatty acids with a preference for C16-C18 unsaturated fatty acids (By similarity). It was suggested that it may also stimulate fatty acid oxidation (By similarity). At the villus tip of the crypt-villus axis of the small intestine may sensitize epithelial cells to apoptosis specifically triggered by the death ligand TRAIL. May have a role in the survival of glioma cells. {ECO:0000250, ECO:0000269|PubMed:17681178, ECO:0000269|PubMed:18806831, ECO:0000269|PubMed:19459852, ECO:0000269|PubMed:22633490, ECO:0000269|PubMed:24269233}. | FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. |
Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
- In-frame and retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
Hgene | ACSL5 | chr10:114186117 | chr14:104212890 | ENST00000354273 | + | 19 | 21 | 12_32 | 613 | 684.0 | Transmembrane | Helical%3B Signal-anchor for type III membrane protein |
Hgene | ACSL5 | chr10:114186117 | chr14:104212890 | ENST00000354655 | + | 19 | 21 | 12_32 | 613 | 684.0 | Transmembrane | Helical%3B Signal-anchor for type III membrane protein |
Hgene | ACSL5 | chr10:114186117 | chr14:104212890 | ENST00000356116 | + | 19 | 21 | 12_32 | 669 | 740.0 | Transmembrane | Helical%3B Signal-anchor for type III membrane protein |
Hgene | ACSL5 | chr10:114186117 | chr14:104212890 | ENST00000393081 | + | 19 | 21 | 12_32 | 613 | 684.0 | Transmembrane | Helical%3B Signal-anchor for type III membrane protein |
Hgene | ACSL5 | chr10:114186117 | chr14:104212890 | ENST00000433418 | + | 19 | 20 | 12_32 | 613 | 660.0 | Transmembrane | Helical%3B Signal-anchor for type III membrane protein |
Tgene | PPP1R13B | chr10:114186117 | chr14:104212890 | ENST00000202556 | 7 | 17 | 428_860 | 323 | 1091.0 | Compositional bias | Note=Pro-rich | |
Tgene | PPP1R13B | chr10:114186117 | chr14:104212890 | ENST00000202556 | 7 | 17 | 1019_1081 | 323 | 1091.0 | Domain | SH3 | |
Tgene | PPP1R13B | chr10:114186117 | chr14:104212890 | ENST00000202556 | 7 | 17 | 920_952 | 323 | 1091.0 | Repeat | Note=ANK 1 | |
Tgene | PPP1R13B | chr10:114186117 | chr14:104212890 | ENST00000202556 | 7 | 17 | 953_985 | 323 | 1091.0 | Repeat | Note=ANK 2 |
- In-frame and not-retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
Hgene | ACSL5 | chr10:114186117 | chr14:104212890 | ENST00000354273 | + | 19 | 21 | 33_683 | 613 | 684.0 | Topological domain | Cytoplasmic |
Hgene | ACSL5 | chr10:114186117 | chr14:104212890 | ENST00000354655 | + | 19 | 21 | 33_683 | 613 | 684.0 | Topological domain | Cytoplasmic |
Hgene | ACSL5 | chr10:114186117 | chr14:104212890 | ENST00000356116 | + | 19 | 21 | 33_683 | 669 | 740.0 | Topological domain | Cytoplasmic |
Hgene | ACSL5 | chr10:114186117 | chr14:104212890 | ENST00000393081 | + | 19 | 21 | 33_683 | 613 | 684.0 | Topological domain | Cytoplasmic |
Hgene | ACSL5 | chr10:114186117 | chr14:104212890 | ENST00000433418 | + | 19 | 20 | 33_683 | 613 | 660.0 | Topological domain | Cytoplasmic |
Tgene | PPP1R13B | chr10:114186117 | chr14:104212890 | ENST00000202556 | 7 | 17 | 132_292 | 323 | 1091.0 | Compositional bias | Note=Gln-rich |
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Fusion Gene Sequence for ACSL5-PPP1R13B |
For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
>1515_1515_1_ACSL5-PPP1R13B_ACSL5_chr10_114186117_ENST00000354273_PPP1R13B_chr14_104212890_ENST00000202556_length(transcript)=5824nt_BP=2118nt AAAACCAGGAAGTGAAGTCCCCGAGCACGTTAGAAAGCCTGACATGGCCTGACTCGGGACAGCTCAGAGCAGGGCAGAACTGGGGACACT CTGGGCCGGCCTTCTGCCTGCATGGACGCTCTGAAGCCACCCTGTCTCTGGAGGAACCACGAGCGAGGGAAGAAGGACAGGGACTCGTGT GGCAGGAAGAACTCAGAGCCGGGAAGCCCCCATTCACTAGAAGCACTGAGAGATGCGGCCCCCTCGCAGGGTCTGAATTTCCTGCTGCTG TTCACAAAGATGCTTTTTATCTTTAACTTTTTGTTTTCCCCACTTCCGACCCCGGCGTTGATCTGCATCCTGACATTTGGAGCTGCCATC TTCTTGTGGCTGATCACCAGACCTCAACCCGTCTTACCTCTTCTTGACCTGAACAATCAGTCTGTGGGAATTGAGGGAGGAGCACGGAAG GGGGTTTCCCAGAAGAACAATGACCTAACAAGTTGCTGCTTCTCAGATGCCAAGACTATGTATGAGGTTTTCCAAAGAGGACTCGCTGTG TCTGACAATGGGCCCTGCTTGGGATATAGAAAACCAAACCAGCCCTACAGATGGCTATCTTACAAACAGGTGTCTGATAGAGCAGAGTAC CTGGGTTCCTGTCTCTTGCATAAAGGTTATAAATCATCACCAGACCAGTTTGTCGGCATCTTTGCTCAGAATAGGCCAGAGTGGATCATC TCCGAATTGGCTTGTTACACGTACTCTATGGTAGCTGTACCTCTGTATGACACCTTGGGACCAGAAGCCATCGTACATATTGTCAACAAG GCTGATATCGCCATGGTGATCTGTGACACACCCCAAAAGGCATTGGTGCTGATAGGGAATGTAGAGAAAGGCTTCACCCCGAGCCTGAAG GTGATCATCCTTATGGACCCCTTTGATGATGACCTGAAGCAAAGAGGGGAGAAGAGTGGAATTGAGATCTTATCCCTATATGATGCTGAG AACCTAGGCAAAGAGCACTTCAGAAAACCTGTGCCTCCTAGCCCAGAAGACCTGAGCGTCATCTGCTTCACCAGTGGGACCACAGGTGAC CCCAAAGGAGCCATGATAACCCATCAAAATATTGTTTCAAATGCTGCTGCCTTTCTCAAATGTGTGGAGCATGCTTATGAGCCCACTCCT GATGATGTGGCCATATCCTACCTCCCTCTGGCTCATATGTTTGAGAGGATTGTACAGGCTGTTGTGTACAGCTGTGGAGCCAGAGTTGGA TTCTTCCAAGGGGATATTCGGTTGCTGGCTGACGACATGAAGACTTTGAAGCCCACATTGTTTCCCGCGGTGCCTCGACTCCTTAACAGG ATCTACGATAAGGTACAAAATGAGGCCAAGACACCCTTGAAGAAGTTCTTGTTGAAGCTGGCTGTTTCCAGTAAATTCAAAGAGCTTCAA AAGGGTATCATCAGGCATGATAGTTTCTGGGACAAGCTCATCTTTGCAAAGATCCAGGACAGCCTGGGCGGAAGGGTTCGTGTAATTGTC ACTGGAGCTGCCCCCATGTCCACTTCAGTCATGACATTCTTCCGGGCAGCAATGGGATGTCAGGTGTATGAAGCTTATGGTCAAACAGAA TGCACAGGTGGCTGTACATTTACATTACCTGGGGACTGGACATCAGGTCACGTTGGGGTGCCCCTGGCTTGCAATTACGTGAAGCTGGAA GATGTGGCTGACATGAACTACTTTACAGTGAATAATGAAGGAGAGGTCTGCATCAAGGGTACAAACGTGTTCAAAGGATACCTGAAGGAC CCTGAGAAGACACAGGAAGCCCTGGACAGTGATGGCTGGCTTCACACAGGAGACATTGGTCGCTGGCTCCCGAATGGAACTCTGAAGATC ATCGACCGTAAAAAGAACATTTTCAAGCTGGCCCAAGGAGAATACATTGCACCAGAGAAGATAGAAAATATCTACAACAGGAGTCAACCA GTGTTACAAATTTTTGTACACGGGGAGAGCTTACGGTCATCCTTAGTAGGAGTGGTGGTTCCTGACACAGATGTACTTCCCTCATTTGCA GCCAAGCTTGGGGTGAAGGGCTCCTTTGAGGAACTGTGCCAAAACCAACTGAACCGTGTGAATGGCACGTCATCACCACAGTCCCCTCTG AGCACATCGGGCAGGGTCGCTGCTGTGGGGCCTTATATCCAGGTTCCCAGTGCCGGAAGCTTTCCTGTGCTGGGGGACCCTATAAAGCCC CAGTCTCTCAGTATTGCCTCAAATGCTGCTCATGGAAGATCCAAATCCGCTAATGATGGAAACTGGCCAACATTAAAACAGAATTCTAGC TCTTCCGTGAAACCAGTGCAGGTGGCCGGTGCAGACTGGAAGGATCCGAGCGTGGAGGGGTCTGTCAAGCAGGGCACTGTCTCCAGCCAG CCTGTGCCCTTCTCAGCACTGGGACCCACGGAGAAGCCGGGCATCGAGATTGGTAAAGTGCCACCTCCCATCCCGGGTGTAGGCAAGCAG CTGCCTCCAAGCTATGGGACATACCCAAGTCCTACACCTCTGGGTCCTGGGTCGACAAGCTCCCTGGAAAGGAGGAAGGAAGGCAGCTTG CCCAGGCCCAGTGCAGGCCTGCCAAGTCGACAGAGGCCCACCCTGCTGCCCGCCACAGGCAGCACCCCCCAGCCAGGCTCCTCACAACAG ATTCAGCAGAGGATTTCCGTACCGCCAAGTCCCACGTACCCGCCAGCGGGACCACCTGCATTTCCAGCTGGGGACAGCAAGCCTGAACTC CCACTGACAGTGGCCATTAGGCCTTTCCTGGCTGATAAAGGGTCAAGGCCACAGTCTCCCAGGAAAGGACCCCAGACAGTGAATTCAAGT TCCATATACTCCATGTACCTCCAGCAAGCCACACCACCTAAGAATTACCAGCCGGCAGCACACAGCGCCTTAAATAAGTCAGTTAAAGCA GTGTATGGTAAGCCCGTTTTACCTTCGGGTTCAACCTCTCCATCGCCGCTGCCGTTTCTTCACGGGTCACTGTCCACGGGCACACCACAG CCTCAGCCACCTTCAGAAAGTACTGAGAAAGAGCCTGAGCAGGATGGCCCCGCCGCCCCCGCAGATGGCAGCACCGTGGAGAGCCTGCCA CGGCCACTCAGCCCCACCAAGCTCACGCCCATCGTGCATTCGCCACTGCGCTACCAGAGTGATGCAGACCTGGAGGCCCTCCGCAGGAAG CTGGCCAACGCGCCCCGGCCCCTGAAAAAGCGCAGCTCCATCACAGAGCCCGAGGGCCCCGGCGGGCCCAACATCCAGAAGCTGCTGTAC CAGCGCTTCAACACCCTGGCCGGTGGCATGGAGGGCACCCCTTTCTACCAGCCCAGCCCCTCCCAGGACTTCATGGGCACCTTGGCCGAT GTGGACAATGGAAACACCAATGCCAATGGAAACCTGGAAGAGCTCCCCCCTGCCCAGCCCACAGCCCCACTCCCCGCTGAGCCTGCCCCG TCATCAGATGCCAATGATAATGAGTTACCTTCCCCCGAACCAGAGGAGCTCATCTGTCCCCAAACCACCCACCAAACTGCCGAGCCGGCA GAGGACAATAACAACAACGTGGCCACGGTCCCCACCACGGAGCAGATCCCGAGTCCTGTGGCTGAGGCCCCATCTCCAGGGGAAGAGCAG GTCCCTCCAGCACCTCTTCCCCCTGCCAGCCACCCTCCTGCCACCTCCACGAACAAGCGGACCAACTTGAAGAAGCCCAACTCGGAGCGG ACGGGGCACGGGCTGAGAGTCCGGTTTAACCCCCTGGCACTGCTCCTAGACGCGTCTCTGGAAGGAGAGTTCGATCTGGTGCAGAGGATC ATCTATGAGGTGGAAGATCCCAGCAAGCCCAACGACGAAGGGATCACCCCACTGCACAACGCCGTCTGCGCCGGCCACCATCACATCGTG AAGTTCCTGCTGGATTTTGGTGTCAACGTGAATGCTGCTGATAGTGATGGATGGACGCCGCTGCACTGCGCTGCCTCTTGTAACAGCGTT CACCTCTGCAAACAGCTGGTGGAGAGTGGTGCCGCCATTTTTGCCTCAACCATAAGCGACATTGAAACTGCTGCAGACAAGTGTGAGGAG ATGGAGGAAGGCTACATCCAGTGCTCCCAGTTTCTATATGGGGTGCAGGAAAAGCTGGGTGTGATGAACAAAGGTGTGGCGTATGCTCTG TGGGACTACGAGGCCCAGAACAGTGACGAGCTGTCCTTCCACGAAGGGGACGCCCTCACCATCCTGAGGCGCAAGGACGAAAGCGAGACT GAGTGGTGGTGGGCTCGCCTTGGAGACCGGGAGGGCTATGTGCCCAAAAACCTGCTGGGGCTGTATCCACGGATCAAACCCCGACAGCGA ACACTCGCCTGAACTTCCTTTTGGAGCACCGCATGGTCTTGCCAGCTACCAGGAGCCACTTAAGAGATTATTGTGCTGTTTTCCAGGAAA GCTGCAGCTAGAAAATGGTCTTAATGGTGCTCACTTTAGCAGACAGCGTCCACAATGTGAATCCTACAGTTTCCAGGTGAGGCCCTTTCT CCAGTTTGCCCATTAACTGGGAGAGGTACTTTCGCCTCCAAGGACTGAATTTTGCCAATTACTATAAATCCAAATAAATACCCACTTTCA AAACACCCACCCCTCTTGCCATTAAGAAGTCCCATAACCCCCGGTTGGTTGCCAGTGAAGACAGAAGCTCTTACTGACTTGGCCCCGAGG CCATCACCCCCTCCAGCAGTGAACACTGTCCGCCGCTGTGAGGCCTGCTCCCCTGCGACCGCCCTGCCCCCCGTCACCGAATCGGACACT CATCCTTTCTCACACTTCCCACACATGATCCTTCTTCCCTTCATCACCAAAGGAGCCTCTGTATGGAAACATGTCCAGTGTTGCTGCCCA GTGTGTATGCCTCCCAGTACCCACTCTGCTCGGCCGCCTTGGGGGTTCCGCTTCCTGTTCCAGTTCACCTAAAGGCTGATTGTGCAGGCC CAGCACTGTGGCTGGACTGCCGCGCCACGGGCACCAGGACCCCTAAGACCAAGTGACAACTGGGAGAGCCTCAGCATATACTCTTCTCCT CCGATCTCACAGCCTGTCATGCTGCTCAGTGTGGTTCTCACCCCTGCAAGCTCAAATTCAGTTCCCTGAATGGAGTCAGGTGCTGGAGGC CGTGGCAGCGGAGGGTGGTTGGGGTTGGGGCTGGGGGTGGACTGGTGTGAGGGCAGACCAGGGCCAGGTAGACGGGGCTGTTTGGTGCCT GAAGGATGGCAGACGCCTGGTGTCAGGAGGGGCCGCCACCAAGGAGCAGCAGCTGGGGCAGAGGAGCTGGGGTCAGGGGCCACCCCTCTC TGCCGATCTCCCTGCCTGGGCTGGCTGTGAGGCCACCTTTGTCCCAGGCCCAGCCTCAAGGCAAGGAGGGCGCTTCACTGAGGTGTGAAT TGTACGTACAGGCTTTTTATATACCAAAAGTATTTTTTGACTAGACCATTCAAAGCTACCCGAACTATGTTGGAAATTTTTTTTTTCTCA TTAAAATACAGGCCCTTAGGCTCTATTTTTCATGTATGAGTCGTGTGTAATTTATGTAAAAATGTGTGTACAGACTCACTGATGCAGCAC TGTAGCCCATCACCTTGGAGCACTGACTGTACATAGTGTGGTGAAGAAAAGTGAACGCCCTTGTAGAGCAGCCCGACCACAGGAGCATGG >1515_1515_1_ACSL5-PPP1R13B_ACSL5_chr10_114186117_ENST00000354273_PPP1R13B_chr14_104212890_ENST00000202556_length(amino acids)=1457AA_BP=690 MTRDSSEQGRTGDTLGRPSACMDALKPPCLWRNHERGKKDRDSCGRKNSEPGSPHSLEALRDAAPSQGLNFLLLFTKMLFIFNFLFSPLP TPALICILTFGAAIFLWLITRPQPVLPLLDLNNQSVGIEGGARKGVSQKNNDLTSCCFSDAKTMYEVFQRGLAVSDNGPCLGYRKPNQPY RWLSYKQVSDRAEYLGSCLLHKGYKSSPDQFVGIFAQNRPEWIISELACYTYSMVAVPLYDTLGPEAIVHIVNKADIAMVICDTPQKALV LIGNVEKGFTPSLKVIILMDPFDDDLKQRGEKSGIEILSLYDAENLGKEHFRKPVPPSPEDLSVICFTSGTTGDPKGAMITHQNIVSNAA AFLKCVEHAYEPTPDDVAISYLPLAHMFERIVQAVVYSCGARVGFFQGDIRLLADDMKTLKPTLFPAVPRLLNRIYDKVQNEAKTPLKKF LLKLAVSSKFKELQKGIIRHDSFWDKLIFAKIQDSLGGRVRVIVTGAAPMSTSVMTFFRAAMGCQVYEAYGQTECTGGCTFTLPGDWTSG HVGVPLACNYVKLEDVADMNYFTVNNEGEVCIKGTNVFKGYLKDPEKTQEALDSDGWLHTGDIGRWLPNGTLKIIDRKKNIFKLAQGEYI APEKIENIYNRSQPVLQIFVHGESLRSSLVGVVVPDTDVLPSFAAKLGVKGSFEELCQNQLNRVNGTSSPQSPLSTSGRVAAVGPYIQVP SAGSFPVLGDPIKPQSLSIASNAAHGRSKSANDGNWPTLKQNSSSSVKPVQVAGADWKDPSVEGSVKQGTVSSQPVPFSALGPTEKPGIE IGKVPPPIPGVGKQLPPSYGTYPSPTPLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTLLPATGSTPQPGSSQQIQQRISVPPSPTYPPA GPPAFPAGDSKPELPLTVAIRPFLADKGSRPQSPRKGPQTVNSSSIYSMYLQQATPPKNYQPAAHSALNKSVKAVYGKPVLPSGSTSPSP LPFLHGSLSTGTPQPQPPSESTEKEPEQDGPAAPADGSTVESLPRPLSPTKLTPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSSITE PEGPGGPNIQKLLYQRFNTLAGGMEGTPFYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAPLPAEPAPSSDANDNELPSPEPEE LICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEAPSPGEEQVPPAPLPPASHPPATSTNKRTNLKKPNSERTGHGLRVRFNPLALLL DASLEGEFDLVQRIIYEVEDPSKPNDEGITPLHNAVCAGHHHIVKFLLDFGVNVNAADSDGWTPLHCAASCNSVHLCKQLVESGAAIFAS TISDIETAADKCEEMEEGYIQCSQFLYGVQEKLGVMNKGVAYALWDYEAQNSDELSFHEGDALTILRRKDESETEWWWARLGDREGYVPK -------------------------------------------------------------- >1515_1515_2_ACSL5-PPP1R13B_ACSL5_chr10_114186117_ENST00000354655_PPP1R13B_chr14_104212890_ENST00000202556_length(transcript)=5826nt_BP=2120nt CTTACTGTCAGAGGTTACTACAAGTGTTTGAACAGGTAACTTCTACCTTTGAACTTCTGTTGTGACAGATTCAAAGGTTCCAGGGGAGTG TGTTGGCCACTCTCAGGACAGTACACAGTAGCTTCGGGTGTGTCCCAGTCAGTCCTAGGAGCTGTGGAAAGAGTAGAAGTGCCTGAATGT GGTGCTGAATCAATACAGCCAGCTGTGAGGGGAGCACTTCCTGGACCCAGGAAGGGAGAGTCTTCTTCCAAGGTCTGAATTTCCTGCTGC TGTTCACAAAGATGCTTTTTATCTTTAACTTTTTGTTTTCCCCACTTCCGACCCCGGCGTTGATCTGCATCCTGACATTTGGAGCTGCCA TCTTCTTGTGGCTGATCACCAGACCTCAACCCGTCTTACCTCTTCTTGACCTGAACAATCAGTCTGTGGGAATTGAGGGAGGAGCACGGA AGGGGGTTTCCCAGAAGAACAATGACCTAACAAGTTGCTGCTTCTCAGATGCCAAGACTATGTATGAGGTTTTCCAAAGAGGACTCGCTG TGTCTGACAATGGGCCCTGCTTGGGATATAGAAAACCAAACCAGCCCTACAGATGGCTATCTTACAAACAGGTGTCTGATAGAGCAGAGT ACCTGGGTTCCTGTCTCTTGCATAAAGGTTATAAATCATCACCAGACCAGTTTGTCGGCATCTTTGCTCAGAATAGGCCAGAGTGGATCA TCTCCGAATTGGCTTGTTACACGTACTCTATGGTAGCTGTACCTCTGTATGACACCTTGGGACCAGAAGCCATCGTACATATTGTCAACA AGGCTGATATCGCCATGGTGATCTGTGACACACCCCAAAAGGCATTGGTGCTGATAGGGAATGTAGAGAAAGGCTTCACCCCGAGCCTGA AGGTGATCATCCTTATGGACCCCTTTGATGATGACCTGAAGCAAAGAGGGGAGAAGAGTGGAATTGAGATCTTATCCCTATATGATGCTG AGAACCTAGGCAAAGAGCACTTCAGAAAACCTGTGCCTCCTAGCCCAGAAGACCTGAGCGTCATCTGCTTCACCAGTGGGACCACAGGTG ACCCCAAAGGAGCCATGATAACCCATCAAAATATTGTTTCAAATGCTGCTGCCTTTCTCAAATGTGTGGAGCATGCTTATGAGCCCACTC CTGATGATGTGGCCATATCCTACCTCCCTCTGGCTCATATGTTTGAGAGGATTGTACAGGCTGTTGTGTACAGCTGTGGAGCCAGAGTTG GATTCTTCCAAGGGGATATTCGGTTGCTGGCTGACGACATGAAGACTTTGAAGCCCACATTGTTTCCCGCGGTGCCTCGACTCCTTAACA GGATCTACGATAAGGTACAAAATGAGGCCAAGACACCCTTGAAGAAGTTCTTGTTGAAGCTGGCTGTTTCCAGTAAATTCAAAGAGCTTC AAAAGGGTATCATCAGGCATGATAGTTTCTGGGACAAGCTCATCTTTGCAAAGATCCAGGACAGCCTGGGCGGAAGGGTTCGTGTAATTG TCACTGGAGCTGCCCCCATGTCCACTTCAGTCATGACATTCTTCCGGGCAGCAATGGGATGTCAGGTGTATGAAGCTTATGGTCAAACAG AATGCACAGGTGGCTGTACATTTACATTACCTGGGGACTGGACATCAGGTCACGTTGGGGTGCCCCTGGCTTGCAATTACGTGAAGCTGG AAGATGTGGCTGACATGAACTACTTTACAGTGAATAATGAAGGAGAGGTCTGCATCAAGGGTACAAACGTGTTCAAAGGATACCTGAAGG ACCCTGAGAAGACACAGGAAGCCCTGGACAGTGATGGCTGGCTTCACACAGGAGACATTGGTCGCTGGCTCCCGAATGGAACTCTGAAGA TCATCGACCGTAAAAAGAACATTTTCAAGCTGGCCCAAGGAGAATACATTGCACCAGAGAAGATAGAAAATATCTACAACAGGAGTCAAC CAGTGTTACAAATTTTTGTACACGGGGAGAGCTTACGGTCATCCTTAGTAGGAGTGGTGGTTCCTGACACAGATGTACTTCCCTCATTTG CAGCCAAGCTTGGGGTGAAGGGCTCCTTTGAGGAACTGTGCCAAAACCAACTGAACCGTGTGAATGGCACGTCATCACCACAGTCCCCTC TGAGCACATCGGGCAGGGTCGCTGCTGTGGGGCCTTATATCCAGGTTCCCAGTGCCGGAAGCTTTCCTGTGCTGGGGGACCCTATAAAGC CCCAGTCTCTCAGTATTGCCTCAAATGCTGCTCATGGAAGATCCAAATCCGCTAATGATGGAAACTGGCCAACATTAAAACAGAATTCTA GCTCTTCCGTGAAACCAGTGCAGGTGGCCGGTGCAGACTGGAAGGATCCGAGCGTGGAGGGGTCTGTCAAGCAGGGCACTGTCTCCAGCC AGCCTGTGCCCTTCTCAGCACTGGGACCCACGGAGAAGCCGGGCATCGAGATTGGTAAAGTGCCACCTCCCATCCCGGGTGTAGGCAAGC AGCTGCCTCCAAGCTATGGGACATACCCAAGTCCTACACCTCTGGGTCCTGGGTCGACAAGCTCCCTGGAAAGGAGGAAGGAAGGCAGCT TGCCCAGGCCCAGTGCAGGCCTGCCAAGTCGACAGAGGCCCACCCTGCTGCCCGCCACAGGCAGCACCCCCCAGCCAGGCTCCTCACAAC AGATTCAGCAGAGGATTTCCGTACCGCCAAGTCCCACGTACCCGCCAGCGGGACCACCTGCATTTCCAGCTGGGGACAGCAAGCCTGAAC TCCCACTGACAGTGGCCATTAGGCCTTTCCTGGCTGATAAAGGGTCAAGGCCACAGTCTCCCAGGAAAGGACCCCAGACAGTGAATTCAA GTTCCATATACTCCATGTACCTCCAGCAAGCCACACCACCTAAGAATTACCAGCCGGCAGCACACAGCGCCTTAAATAAGTCAGTTAAAG CAGTGTATGGTAAGCCCGTTTTACCTTCGGGTTCAACCTCTCCATCGCCGCTGCCGTTTCTTCACGGGTCACTGTCCACGGGCACACCAC AGCCTCAGCCACCTTCAGAAAGTACTGAGAAAGAGCCTGAGCAGGATGGCCCCGCCGCCCCCGCAGATGGCAGCACCGTGGAGAGCCTGC CACGGCCACTCAGCCCCACCAAGCTCACGCCCATCGTGCATTCGCCACTGCGCTACCAGAGTGATGCAGACCTGGAGGCCCTCCGCAGGA AGCTGGCCAACGCGCCCCGGCCCCTGAAAAAGCGCAGCTCCATCACAGAGCCCGAGGGCCCCGGCGGGCCCAACATCCAGAAGCTGCTGT ACCAGCGCTTCAACACCCTGGCCGGTGGCATGGAGGGCACCCCTTTCTACCAGCCCAGCCCCTCCCAGGACTTCATGGGCACCTTGGCCG ATGTGGACAATGGAAACACCAATGCCAATGGAAACCTGGAAGAGCTCCCCCCTGCCCAGCCCACAGCCCCACTCCCCGCTGAGCCTGCCC CGTCATCAGATGCCAATGATAATGAGTTACCTTCCCCCGAACCAGAGGAGCTCATCTGTCCCCAAACCACCCACCAAACTGCCGAGCCGG CAGAGGACAATAACAACAACGTGGCCACGGTCCCCACCACGGAGCAGATCCCGAGTCCTGTGGCTGAGGCCCCATCTCCAGGGGAAGAGC AGGTCCCTCCAGCACCTCTTCCCCCTGCCAGCCACCCTCCTGCCACCTCCACGAACAAGCGGACCAACTTGAAGAAGCCCAACTCGGAGC GGACGGGGCACGGGCTGAGAGTCCGGTTTAACCCCCTGGCACTGCTCCTAGACGCGTCTCTGGAAGGAGAGTTCGATCTGGTGCAGAGGA TCATCTATGAGGTGGAAGATCCCAGCAAGCCCAACGACGAAGGGATCACCCCACTGCACAACGCCGTCTGCGCCGGCCACCATCACATCG TGAAGTTCCTGCTGGATTTTGGTGTCAACGTGAATGCTGCTGATAGTGATGGATGGACGCCGCTGCACTGCGCTGCCTCTTGTAACAGCG TTCACCTCTGCAAACAGCTGGTGGAGAGTGGTGCCGCCATTTTTGCCTCAACCATAAGCGACATTGAAACTGCTGCAGACAAGTGTGAGG AGATGGAGGAAGGCTACATCCAGTGCTCCCAGTTTCTATATGGGGTGCAGGAAAAGCTGGGTGTGATGAACAAAGGTGTGGCGTATGCTC TGTGGGACTACGAGGCCCAGAACAGTGACGAGCTGTCCTTCCACGAAGGGGACGCCCTCACCATCCTGAGGCGCAAGGACGAAAGCGAGA CTGAGTGGTGGTGGGCTCGCCTTGGAGACCGGGAGGGCTATGTGCCCAAAAACCTGCTGGGGCTGTATCCACGGATCAAACCCCGACAGC GAACACTCGCCTGAACTTCCTTTTGGAGCACCGCATGGTCTTGCCAGCTACCAGGAGCCACTTAAGAGATTATTGTGCTGTTTTCCAGGA AAGCTGCAGCTAGAAAATGGTCTTAATGGTGCTCACTTTAGCAGACAGCGTCCACAATGTGAATCCTACAGTTTCCAGGTGAGGCCCTTT CTCCAGTTTGCCCATTAACTGGGAGAGGTACTTTCGCCTCCAAGGACTGAATTTTGCCAATTACTATAAATCCAAATAAATACCCACTTT CAAAACACCCACCCCTCTTGCCATTAAGAAGTCCCATAACCCCCGGTTGGTTGCCAGTGAAGACAGAAGCTCTTACTGACTTGGCCCCGA GGCCATCACCCCCTCCAGCAGTGAACACTGTCCGCCGCTGTGAGGCCTGCTCCCCTGCGACCGCCCTGCCCCCCGTCACCGAATCGGACA CTCATCCTTTCTCACACTTCCCACACATGATCCTTCTTCCCTTCATCACCAAAGGAGCCTCTGTATGGAAACATGTCCAGTGTTGCTGCC CAGTGTGTATGCCTCCCAGTACCCACTCTGCTCGGCCGCCTTGGGGGTTCCGCTTCCTGTTCCAGTTCACCTAAAGGCTGATTGTGCAGG CCCAGCACTGTGGCTGGACTGCCGCGCCACGGGCACCAGGACCCCTAAGACCAAGTGACAACTGGGAGAGCCTCAGCATATACTCTTCTC CTCCGATCTCACAGCCTGTCATGCTGCTCAGTGTGGTTCTCACCCCTGCAAGCTCAAATTCAGTTCCCTGAATGGAGTCAGGTGCTGGAG GCCGTGGCAGCGGAGGGTGGTTGGGGTTGGGGCTGGGGGTGGACTGGTGTGAGGGCAGACCAGGGCCAGGTAGACGGGGCTGTTTGGTGC CTGAAGGATGGCAGACGCCTGGTGTCAGGAGGGGCCGCCACCAAGGAGCAGCAGCTGGGGCAGAGGAGCTGGGGTCAGGGGCCACCCCTC TCTGCCGATCTCCCTGCCTGGGCTGGCTGTGAGGCCACCTTTGTCCCAGGCCCAGCCTCAAGGCAAGGAGGGCGCTTCACTGAGGTGTGA ATTGTACGTACAGGCTTTTTATATACCAAAAGTATTTTTTGACTAGACCATTCAAAGCTACCCGAACTATGTTGGAAATTTTTTTTTTCT CATTAAAATACAGGCCCTTAGGCTCTATTTTTCATGTATGAGTCGTGTGTAATTTATGTAAAAATGTGTGTACAGACTCACTGATGCAGC ACTGTAGCCCATCACCTTGGAGCACTGACTGTACATAGTGTGGTGAAGAAAAGTGAACGCCCTTGTAGAGCAGCCCGACCACAGGAGCAT >1515_1515_2_ACSL5-PPP1R13B_ACSL5_chr10_114186117_ENST00000354655_PPP1R13B_chr14_104212890_ENST00000202556_length(amino acids)=1389AA_BP=622 MNFLLLFTKMLFIFNFLFSPLPTPALICILTFGAAIFLWLITRPQPVLPLLDLNNQSVGIEGGARKGVSQKNNDLTSCCFSDAKTMYEVF QRGLAVSDNGPCLGYRKPNQPYRWLSYKQVSDRAEYLGSCLLHKGYKSSPDQFVGIFAQNRPEWIISELACYTYSMVAVPLYDTLGPEAI VHIVNKADIAMVICDTPQKALVLIGNVEKGFTPSLKVIILMDPFDDDLKQRGEKSGIEILSLYDAENLGKEHFRKPVPPSPEDLSVICFT SGTTGDPKGAMITHQNIVSNAAAFLKCVEHAYEPTPDDVAISYLPLAHMFERIVQAVVYSCGARVGFFQGDIRLLADDMKTLKPTLFPAV PRLLNRIYDKVQNEAKTPLKKFLLKLAVSSKFKELQKGIIRHDSFWDKLIFAKIQDSLGGRVRVIVTGAAPMSTSVMTFFRAAMGCQVYE AYGQTECTGGCTFTLPGDWTSGHVGVPLACNYVKLEDVADMNYFTVNNEGEVCIKGTNVFKGYLKDPEKTQEALDSDGWLHTGDIGRWLP NGTLKIIDRKKNIFKLAQGEYIAPEKIENIYNRSQPVLQIFVHGESLRSSLVGVVVPDTDVLPSFAAKLGVKGSFEELCQNQLNRVNGTS SPQSPLSTSGRVAAVGPYIQVPSAGSFPVLGDPIKPQSLSIASNAAHGRSKSANDGNWPTLKQNSSSSVKPVQVAGADWKDPSVEGSVKQ GTVSSQPVPFSALGPTEKPGIEIGKVPPPIPGVGKQLPPSYGTYPSPTPLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTLLPATGSTPQ PGSSQQIQQRISVPPSPTYPPAGPPAFPAGDSKPELPLTVAIRPFLADKGSRPQSPRKGPQTVNSSSIYSMYLQQATPPKNYQPAAHSAL NKSVKAVYGKPVLPSGSTSPSPLPFLHGSLSTGTPQPQPPSESTEKEPEQDGPAAPADGSTVESLPRPLSPTKLTPIVHSPLRYQSDADL EALRRKLANAPRPLKKRSSITEPEGPGGPNIQKLLYQRFNTLAGGMEGTPFYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAPL PAEPAPSSDANDNELPSPEPEELICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEAPSPGEEQVPPAPLPPASHPPATSTNKRTNLK KPNSERTGHGLRVRFNPLALLLDASLEGEFDLVQRIIYEVEDPSKPNDEGITPLHNAVCAGHHHIVKFLLDFGVNVNAADSDGWTPLHCA ASCNSVHLCKQLVESGAAIFASTISDIETAADKCEEMEEGYIQCSQFLYGVQEKLGVMNKGVAYALWDYEAQNSDELSFHEGDALTILRR -------------------------------------------------------------- >1515_1515_3_ACSL5-PPP1R13B_ACSL5_chr10_114186117_ENST00000356116_PPP1R13B_chr14_104212890_ENST00000202556_length(transcript)=5825nt_BP=2119nt TAAAACCAGGAAGTGAAGTCCCCGAGCACGTTAGAAAGCCTGACATGGCCTGACTCGGGACAGCTCAGAGCAGGGCAGAACTGGGGACAC TCTGGGCCGGCCTTCTGCCTGCATGGACGCTCTGAAGCCACCCTGTCTCTGGAGGAACCACGAGCGAGGGAAGAAGGACAGGGACTCGTG TGGCAGGAAGAACTCAGAGCCGGGAAGCCCCCATTCACTAGAAGCACTGAGAGATGCGGCCCCCTCGCAGGGTCTGAATTTCCTGCTGCT GTTCACAAAGATGCTTTTTATCTTTAACTTTTTGTTTTCCCCACTTCCGACCCCGGCGTTGATCTGCATCCTGACATTTGGAGCTGCCAT CTTCTTGTGGCTGATCACCAGACCTCAACCCGTCTTACCTCTTCTTGACCTGAACAATCAGTCTGTGGGAATTGAGGGAGGAGCACGGAA GGGGGTTTCCCAGAAGAACAATGACCTAACAAGTTGCTGCTTCTCAGATGCCAAGACTATGTATGAGGTTTTCCAAAGAGGACTCGCTGT GTCTGACAATGGGCCCTGCTTGGGATATAGAAAACCAAACCAGCCCTACAGATGGCTATCTTACAAACAGGTGTCTGATAGAGCAGAGTA CCTGGGTTCCTGTCTCTTGCATAAAGGTTATAAATCATCACCAGACCAGTTTGTCGGCATCTTTGCTCAGAATAGGCCAGAGTGGATCAT CTCCGAATTGGCTTGTTACACGTACTCTATGGTAGCTGTACCTCTGTATGACACCTTGGGACCAGAAGCCATCGTACATATTGTCAACAA GGCTGATATCGCCATGGTGATCTGTGACACACCCCAAAAGGCATTGGTGCTGATAGGGAATGTAGAGAAAGGCTTCACCCCGAGCCTGAA GGTGATCATCCTTATGGACCCCTTTGATGATGACCTGAAGCAAAGAGGGGAGAAGAGTGGAATTGAGATCTTATCCCTATATGATGCTGA GAACCTAGGCAAAGAGCACTTCAGAAAACCTGTGCCTCCTAGCCCAGAAGACCTGAGCGTCATCTGCTTCACCAGTGGGACCACAGGTGA CCCCAAAGGAGCCATGATAACCCATCAAAATATTGTTTCAAATGCTGCTGCCTTTCTCAAATGTGTGGAGCATGCTTATGAGCCCACTCC TGATGATGTGGCCATATCCTACCTCCCTCTGGCTCATATGTTTGAGAGGATTGTACAGGCTGTTGTGTACAGCTGTGGAGCCAGAGTTGG ATTCTTCCAAGGGGATATTCGGTTGCTGGCTGACGACATGAAGACTTTGAAGCCCACATTGTTTCCCGCGGTGCCTCGACTCCTTAACAG GATCTACGATAAGGTACAAAATGAGGCCAAGACACCCTTGAAGAAGTTCTTGTTGAAGCTGGCTGTTTCCAGTAAATTCAAAGAGCTTCA AAAGGGTATCATCAGGCATGATAGTTTCTGGGACAAGCTCATCTTTGCAAAGATCCAGGACAGCCTGGGCGGAAGGGTTCGTGTAATTGT CACTGGAGCTGCCCCCATGTCCACTTCAGTCATGACATTCTTCCGGGCAGCAATGGGATGTCAGGTGTATGAAGCTTATGGTCAAACAGA ATGCACAGGTGGCTGTACATTTACATTACCTGGGGACTGGACATCAGGTCACGTTGGGGTGCCCCTGGCTTGCAATTACGTGAAGCTGGA AGATGTGGCTGACATGAACTACTTTACAGTGAATAATGAAGGAGAGGTCTGCATCAAGGGTACAAACGTGTTCAAAGGATACCTGAAGGA CCCTGAGAAGACACAGGAAGCCCTGGACAGTGATGGCTGGCTTCACACAGGAGACATTGGTCGCTGGCTCCCGAATGGAACTCTGAAGAT CATCGACCGTAAAAAGAACATTTTCAAGCTGGCCCAAGGAGAATACATTGCACCAGAGAAGATAGAAAATATCTACAACAGGAGTCAACC AGTGTTACAAATTTTTGTACACGGGGAGAGCTTACGGTCATCCTTAGTAGGAGTGGTGGTTCCTGACACAGATGTACTTCCCTCATTTGC AGCCAAGCTTGGGGTGAAGGGCTCCTTTGAGGAACTGTGCCAAAACCAACTGAACCGTGTGAATGGCACGTCATCACCACAGTCCCCTCT GAGCACATCGGGCAGGGTCGCTGCTGTGGGGCCTTATATCCAGGTTCCCAGTGCCGGAAGCTTTCCTGTGCTGGGGGACCCTATAAAGCC CCAGTCTCTCAGTATTGCCTCAAATGCTGCTCATGGAAGATCCAAATCCGCTAATGATGGAAACTGGCCAACATTAAAACAGAATTCTAG CTCTTCCGTGAAACCAGTGCAGGTGGCCGGTGCAGACTGGAAGGATCCGAGCGTGGAGGGGTCTGTCAAGCAGGGCACTGTCTCCAGCCA GCCTGTGCCCTTCTCAGCACTGGGACCCACGGAGAAGCCGGGCATCGAGATTGGTAAAGTGCCACCTCCCATCCCGGGTGTAGGCAAGCA GCTGCCTCCAAGCTATGGGACATACCCAAGTCCTACACCTCTGGGTCCTGGGTCGACAAGCTCCCTGGAAAGGAGGAAGGAAGGCAGCTT GCCCAGGCCCAGTGCAGGCCTGCCAAGTCGACAGAGGCCCACCCTGCTGCCCGCCACAGGCAGCACCCCCCAGCCAGGCTCCTCACAACA GATTCAGCAGAGGATTTCCGTACCGCCAAGTCCCACGTACCCGCCAGCGGGACCACCTGCATTTCCAGCTGGGGACAGCAAGCCTGAACT CCCACTGACAGTGGCCATTAGGCCTTTCCTGGCTGATAAAGGGTCAAGGCCACAGTCTCCCAGGAAAGGACCCCAGACAGTGAATTCAAG TTCCATATACTCCATGTACCTCCAGCAAGCCACACCACCTAAGAATTACCAGCCGGCAGCACACAGCGCCTTAAATAAGTCAGTTAAAGC AGTGTATGGTAAGCCCGTTTTACCTTCGGGTTCAACCTCTCCATCGCCGCTGCCGTTTCTTCACGGGTCACTGTCCACGGGCACACCACA GCCTCAGCCACCTTCAGAAAGTACTGAGAAAGAGCCTGAGCAGGATGGCCCCGCCGCCCCCGCAGATGGCAGCACCGTGGAGAGCCTGCC ACGGCCACTCAGCCCCACCAAGCTCACGCCCATCGTGCATTCGCCACTGCGCTACCAGAGTGATGCAGACCTGGAGGCCCTCCGCAGGAA GCTGGCCAACGCGCCCCGGCCCCTGAAAAAGCGCAGCTCCATCACAGAGCCCGAGGGCCCCGGCGGGCCCAACATCCAGAAGCTGCTGTA CCAGCGCTTCAACACCCTGGCCGGTGGCATGGAGGGCACCCCTTTCTACCAGCCCAGCCCCTCCCAGGACTTCATGGGCACCTTGGCCGA TGTGGACAATGGAAACACCAATGCCAATGGAAACCTGGAAGAGCTCCCCCCTGCCCAGCCCACAGCCCCACTCCCCGCTGAGCCTGCCCC GTCATCAGATGCCAATGATAATGAGTTACCTTCCCCCGAACCAGAGGAGCTCATCTGTCCCCAAACCACCCACCAAACTGCCGAGCCGGC AGAGGACAATAACAACAACGTGGCCACGGTCCCCACCACGGAGCAGATCCCGAGTCCTGTGGCTGAGGCCCCATCTCCAGGGGAAGAGCA GGTCCCTCCAGCACCTCTTCCCCCTGCCAGCCACCCTCCTGCCACCTCCACGAACAAGCGGACCAACTTGAAGAAGCCCAACTCGGAGCG GACGGGGCACGGGCTGAGAGTCCGGTTTAACCCCCTGGCACTGCTCCTAGACGCGTCTCTGGAAGGAGAGTTCGATCTGGTGCAGAGGAT CATCTATGAGGTGGAAGATCCCAGCAAGCCCAACGACGAAGGGATCACCCCACTGCACAACGCCGTCTGCGCCGGCCACCATCACATCGT GAAGTTCCTGCTGGATTTTGGTGTCAACGTGAATGCTGCTGATAGTGATGGATGGACGCCGCTGCACTGCGCTGCCTCTTGTAACAGCGT TCACCTCTGCAAACAGCTGGTGGAGAGTGGTGCCGCCATTTTTGCCTCAACCATAAGCGACATTGAAACTGCTGCAGACAAGTGTGAGGA GATGGAGGAAGGCTACATCCAGTGCTCCCAGTTTCTATATGGGGTGCAGGAAAAGCTGGGTGTGATGAACAAAGGTGTGGCGTATGCTCT GTGGGACTACGAGGCCCAGAACAGTGACGAGCTGTCCTTCCACGAAGGGGACGCCCTCACCATCCTGAGGCGCAAGGACGAAAGCGAGAC TGAGTGGTGGTGGGCTCGCCTTGGAGACCGGGAGGGCTATGTGCCCAAAAACCTGCTGGGGCTGTATCCACGGATCAAACCCCGACAGCG AACACTCGCCTGAACTTCCTTTTGGAGCACCGCATGGTCTTGCCAGCTACCAGGAGCCACTTAAGAGATTATTGTGCTGTTTTCCAGGAA AGCTGCAGCTAGAAAATGGTCTTAATGGTGCTCACTTTAGCAGACAGCGTCCACAATGTGAATCCTACAGTTTCCAGGTGAGGCCCTTTC TCCAGTTTGCCCATTAACTGGGAGAGGTACTTTCGCCTCCAAGGACTGAATTTTGCCAATTACTATAAATCCAAATAAATACCCACTTTC AAAACACCCACCCCTCTTGCCATTAAGAAGTCCCATAACCCCCGGTTGGTTGCCAGTGAAGACAGAAGCTCTTACTGACTTGGCCCCGAG GCCATCACCCCCTCCAGCAGTGAACACTGTCCGCCGCTGTGAGGCCTGCTCCCCTGCGACCGCCCTGCCCCCCGTCACCGAATCGGACAC TCATCCTTTCTCACACTTCCCACACATGATCCTTCTTCCCTTCATCACCAAAGGAGCCTCTGTATGGAAACATGTCCAGTGTTGCTGCCC AGTGTGTATGCCTCCCAGTACCCACTCTGCTCGGCCGCCTTGGGGGTTCCGCTTCCTGTTCCAGTTCACCTAAAGGCTGATTGTGCAGGC CCAGCACTGTGGCTGGACTGCCGCGCCACGGGCACCAGGACCCCTAAGACCAAGTGACAACTGGGAGAGCCTCAGCATATACTCTTCTCC TCCGATCTCACAGCCTGTCATGCTGCTCAGTGTGGTTCTCACCCCTGCAAGCTCAAATTCAGTTCCCTGAATGGAGTCAGGTGCTGGAGG CCGTGGCAGCGGAGGGTGGTTGGGGTTGGGGCTGGGGGTGGACTGGTGTGAGGGCAGACCAGGGCCAGGTAGACGGGGCTGTTTGGTGCC TGAAGGATGGCAGACGCCTGGTGTCAGGAGGGGCCGCCACCAAGGAGCAGCAGCTGGGGCAGAGGAGCTGGGGTCAGGGGCCACCCCTCT CTGCCGATCTCCCTGCCTGGGCTGGCTGTGAGGCCACCTTTGTCCCAGGCCCAGCCTCAAGGCAAGGAGGGCGCTTCACTGAGGTGTGAA TTGTACGTACAGGCTTTTTATATACCAAAAGTATTTTTTGACTAGACCATTCAAAGCTACCCGAACTATGTTGGAAATTTTTTTTTTCTC ATTAAAATACAGGCCCTTAGGCTCTATTTTTCATGTATGAGTCGTGTGTAATTTATGTAAAAATGTGTGTACAGACTCACTGATGCAGCA CTGTAGCCCATCACCTTGGAGCACTGACTGTACATAGTGTGGTGAAGAAAAGTGAACGCCCTTGTAGAGCAGCCCGACCACAGGAGCATG >1515_1515_3_ACSL5-PPP1R13B_ACSL5_chr10_114186117_ENST00000356116_PPP1R13B_chr14_104212890_ENST00000202556_length(amino acids)=1457AA_BP=690 MTRDSSEQGRTGDTLGRPSACMDALKPPCLWRNHERGKKDRDSCGRKNSEPGSPHSLEALRDAAPSQGLNFLLLFTKMLFIFNFLFSPLP TPALICILTFGAAIFLWLITRPQPVLPLLDLNNQSVGIEGGARKGVSQKNNDLTSCCFSDAKTMYEVFQRGLAVSDNGPCLGYRKPNQPY RWLSYKQVSDRAEYLGSCLLHKGYKSSPDQFVGIFAQNRPEWIISELACYTYSMVAVPLYDTLGPEAIVHIVNKADIAMVICDTPQKALV LIGNVEKGFTPSLKVIILMDPFDDDLKQRGEKSGIEILSLYDAENLGKEHFRKPVPPSPEDLSVICFTSGTTGDPKGAMITHQNIVSNAA AFLKCVEHAYEPTPDDVAISYLPLAHMFERIVQAVVYSCGARVGFFQGDIRLLADDMKTLKPTLFPAVPRLLNRIYDKVQNEAKTPLKKF LLKLAVSSKFKELQKGIIRHDSFWDKLIFAKIQDSLGGRVRVIVTGAAPMSTSVMTFFRAAMGCQVYEAYGQTECTGGCTFTLPGDWTSG HVGVPLACNYVKLEDVADMNYFTVNNEGEVCIKGTNVFKGYLKDPEKTQEALDSDGWLHTGDIGRWLPNGTLKIIDRKKNIFKLAQGEYI APEKIENIYNRSQPVLQIFVHGESLRSSLVGVVVPDTDVLPSFAAKLGVKGSFEELCQNQLNRVNGTSSPQSPLSTSGRVAAVGPYIQVP SAGSFPVLGDPIKPQSLSIASNAAHGRSKSANDGNWPTLKQNSSSSVKPVQVAGADWKDPSVEGSVKQGTVSSQPVPFSALGPTEKPGIE IGKVPPPIPGVGKQLPPSYGTYPSPTPLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTLLPATGSTPQPGSSQQIQQRISVPPSPTYPPA GPPAFPAGDSKPELPLTVAIRPFLADKGSRPQSPRKGPQTVNSSSIYSMYLQQATPPKNYQPAAHSALNKSVKAVYGKPVLPSGSTSPSP LPFLHGSLSTGTPQPQPPSESTEKEPEQDGPAAPADGSTVESLPRPLSPTKLTPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSSITE PEGPGGPNIQKLLYQRFNTLAGGMEGTPFYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAPLPAEPAPSSDANDNELPSPEPEE LICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEAPSPGEEQVPPAPLPPASHPPATSTNKRTNLKKPNSERTGHGLRVRFNPLALLL DASLEGEFDLVQRIIYEVEDPSKPNDEGITPLHNAVCAGHHHIVKFLLDFGVNVNAADSDGWTPLHCAASCNSVHLCKQLVESGAAIFAS TISDIETAADKCEEMEEGYIQCSQFLYGVQEKLGVMNKGVAYALWDYEAQNSDELSFHEGDALTILRRKDESETEWWWARLGDREGYVPK -------------------------------------------------------------- >1515_1515_4_ACSL5-PPP1R13B_ACSL5_chr10_114186117_ENST00000369410_PPP1R13B_chr14_104212890_ENST00000202556_length(transcript)=5055nt_BP=1349nt ATTGGTGCTGATAGGGAATGTAGAGAAAGGCTTCACCCCGAGCCTGAAGGTGATCATCCTTATGGACCCCTTTGATGATGACCTGAAGCA AAGAGGGGAGAAGAGTGGAATTGAGATCTTATCCCTATATGATGCTGAGGTAGATGATTTTCTAGAGAAATCTTATGCTCTTCCCTGGGG CTTCCATTGTTCCTGAATGTTGGCTTCTGGTCCTGATCCAGAACCTAGGCAAAGAGCACTTCAGAAAACCTGTGCCTCCTAGCCCAGAAG ACCTGAGCGTCATCTGCTTCACCAGTGGGACCACAGGTGACCCCAAAGGAGCCATGATAACCCATCAAAATATTGTTTCAAATGCTGCTG CCTTTCTCAAATGTGTGGAGCATGCTTATGAGCCCACTCCTGATGATGTGGCCATATCCTACCTCCCTCTGGCTCATATGTTTGAGAGGA TTGTACAGGCTGTTGTGTACAGCTGTGGAGCCAGAGTTGGATTCTTCCAAGGGGATATTCGGTTGCTGGCTGACGACATGAAGACTTTGA AGCCCACATTGTTTCCCGCGGTGCCTCGACTCCTTAACAGGATCTACGATAAGGTACAAAATGAGGCCAAGACACCCTTGAAGAAGTTCT TGTTGAAGCTGGCTGTTTCCAGTAAATTCAAAGAGCTTCAAAAGGGTATCATCAGGCATGATAGTTTCTGGGACAAGCTCATCTTTGCAA AGATCCAGGACAGCCTGGGCGGAAGGGTTCGTGTAATTGTCACTGGAGCTGCCCCCATGTCCACTTCAGTCATGACATTCTTCCGGGCAG CAATGGGATGTCAGGTGTATGAAGCTTATGGTCAAACAGAATGCACAGGTGGCTGTACATTTACATTACCTGGGGACTGGACATCAGGTC ACGTTGGGGTGCCCCTGGCTTGCAATTACGTGAAGCTGGAAGATGTGGCTGACATGAACTACTTTACAGTGAATAATGAAGGAGAGGTCT GCATCAAGGGTACAAACGTGTTCAAAGGATACCTGAAGGACCCTGAGAAGACACAGGAAGCCCTGGACAGTGATGGCTGGCTTCACACAG GAGACATTGGTCGCTGGCTCCCGAATGGAACTCTGAAGATCATCGACCGTAAAAAGAACATTTTCAAGCTGGCCCAAGGAGAATACATTG CACCAGAGAAGATAGAAAATATCTACAACAGGAGTCAACCAGTGTTACAAATTTTTGTACACGGGGAGAGCTTACGGTCATCCTTAGTAG GAGTGGTGGTTCCTGACACAGATGTACTTCCCTCATTTGCAGCCAAGCTTGGGGTGAAGGGCTCCTTTGAGGAACTGTGCCAAAACCAAC TGAACCGTGTGAATGGCACGTCATCACCACAGTCCCCTCTGAGCACATCGGGCAGGGTCGCTGCTGTGGGGCCTTATATCCAGGTTCCCA GTGCCGGAAGCTTTCCTGTGCTGGGGGACCCTATAAAGCCCCAGTCTCTCAGTATTGCCTCAAATGCTGCTCATGGAAGATCCAAATCCG CTAATGATGGAAACTGGCCAACATTAAAACAGAATTCTAGCTCTTCCGTGAAACCAGTGCAGGTGGCCGGTGCAGACTGGAAGGATCCGA GCGTGGAGGGGTCTGTCAAGCAGGGCACTGTCTCCAGCCAGCCTGTGCCCTTCTCAGCACTGGGACCCACGGAGAAGCCGGGCATCGAGA TTGGTAAAGTGCCACCTCCCATCCCGGGTGTAGGCAAGCAGCTGCCTCCAAGCTATGGGACATACCCAAGTCCTACACCTCTGGGTCCTG GGTCGACAAGCTCCCTGGAAAGGAGGAAGGAAGGCAGCTTGCCCAGGCCCAGTGCAGGCCTGCCAAGTCGACAGAGGCCCACCCTGCTGC CCGCCACAGGCAGCACCCCCCAGCCAGGCTCCTCACAACAGATTCAGCAGAGGATTTCCGTACCGCCAAGTCCCACGTACCCGCCAGCGG GACCACCTGCATTTCCAGCTGGGGACAGCAAGCCTGAACTCCCACTGACAGTGGCCATTAGGCCTTTCCTGGCTGATAAAGGGTCAAGGC CACAGTCTCCCAGGAAAGGACCCCAGACAGTGAATTCAAGTTCCATATACTCCATGTACCTCCAGCAAGCCACACCACCTAAGAATTACC AGCCGGCAGCACACAGCGCCTTAAATAAGTCAGTTAAAGCAGTGTATGGTAAGCCCGTTTTACCTTCGGGTTCAACCTCTCCATCGCCGC TGCCGTTTCTTCACGGGTCACTGTCCACGGGCACACCACAGCCTCAGCCACCTTCAGAAAGTACTGAGAAAGAGCCTGAGCAGGATGGCC CCGCCGCCCCCGCAGATGGCAGCACCGTGGAGAGCCTGCCACGGCCACTCAGCCCCACCAAGCTCACGCCCATCGTGCATTCGCCACTGC GCTACCAGAGTGATGCAGACCTGGAGGCCCTCCGCAGGAAGCTGGCCAACGCGCCCCGGCCCCTGAAAAAGCGCAGCTCCATCACAGAGC CCGAGGGCCCCGGCGGGCCCAACATCCAGAAGCTGCTGTACCAGCGCTTCAACACCCTGGCCGGTGGCATGGAGGGCACCCCTTTCTACC AGCCCAGCCCCTCCCAGGACTTCATGGGCACCTTGGCCGATGTGGACAATGGAAACACCAATGCCAATGGAAACCTGGAAGAGCTCCCCC CTGCCCAGCCCACAGCCCCACTCCCCGCTGAGCCTGCCCCGTCATCAGATGCCAATGATAATGAGTTACCTTCCCCCGAACCAGAGGAGC TCATCTGTCCCCAAACCACCCACCAAACTGCCGAGCCGGCAGAGGACAATAACAACAACGTGGCCACGGTCCCCACCACGGAGCAGATCC CGAGTCCTGTGGCTGAGGCCCCATCTCCAGGGGAAGAGCAGGTCCCTCCAGCACCTCTTCCCCCTGCCAGCCACCCTCCTGCCACCTCCA CGAACAAGCGGACCAACTTGAAGAAGCCCAACTCGGAGCGGACGGGGCACGGGCTGAGAGTCCGGTTTAACCCCCTGGCACTGCTCCTAG ACGCGTCTCTGGAAGGAGAGTTCGATCTGGTGCAGAGGATCATCTATGAGGTGGAAGATCCCAGCAAGCCCAACGACGAAGGGATCACCC CACTGCACAACGCCGTCTGCGCCGGCCACCATCACATCGTGAAGTTCCTGCTGGATTTTGGTGTCAACGTGAATGCTGCTGATAGTGATG GATGGACGCCGCTGCACTGCGCTGCCTCTTGTAACAGCGTTCACCTCTGCAAACAGCTGGTGGAGAGTGGTGCCGCCATTTTTGCCTCAA CCATAAGCGACATTGAAACTGCTGCAGACAAGTGTGAGGAGATGGAGGAAGGCTACATCCAGTGCTCCCAGTTTCTATATGGGGTGCAGG AAAAGCTGGGTGTGATGAACAAAGGTGTGGCGTATGCTCTGTGGGACTACGAGGCCCAGAACAGTGACGAGCTGTCCTTCCACGAAGGGG ACGCCCTCACCATCCTGAGGCGCAAGGACGAAAGCGAGACTGAGTGGTGGTGGGCTCGCCTTGGAGACCGGGAGGGCTATGTGCCCAAAA ACCTGCTGGGGCTGTATCCACGGATCAAACCCCGACAGCGAACACTCGCCTGAACTTCCTTTTGGAGCACCGCATGGTCTTGCCAGCTAC CAGGAGCCACTTAAGAGATTATTGTGCTGTTTTCCAGGAAAGCTGCAGCTAGAAAATGGTCTTAATGGTGCTCACTTTAGCAGACAGCGT CCACAATGTGAATCCTACAGTTTCCAGGTGAGGCCCTTTCTCCAGTTTGCCCATTAACTGGGAGAGGTACTTTCGCCTCCAAGGACTGAA TTTTGCCAATTACTATAAATCCAAATAAATACCCACTTTCAAAACACCCACCCCTCTTGCCATTAAGAAGTCCCATAACCCCCGGTTGGT TGCCAGTGAAGACAGAAGCTCTTACTGACTTGGCCCCGAGGCCATCACCCCCTCCAGCAGTGAACACTGTCCGCCGCTGTGAGGCCTGCT CCCCTGCGACCGCCCTGCCCCCCGTCACCGAATCGGACACTCATCCTTTCTCACACTTCCCACACATGATCCTTCTTCCCTTCATCACCA AAGGAGCCTCTGTATGGAAACATGTCCAGTGTTGCTGCCCAGTGTGTATGCCTCCCAGTACCCACTCTGCTCGGCCGCCTTGGGGGTTCC GCTTCCTGTTCCAGTTCACCTAAAGGCTGATTGTGCAGGCCCAGCACTGTGGCTGGACTGCCGCGCCACGGGCACCAGGACCCCTAAGAC CAAGTGACAACTGGGAGAGCCTCAGCATATACTCTTCTCCTCCGATCTCACAGCCTGTCATGCTGCTCAGTGTGGTTCTCACCCCTGCAA GCTCAAATTCAGTTCCCTGAATGGAGTCAGGTGCTGGAGGCCGTGGCAGCGGAGGGTGGTTGGGGTTGGGGCTGGGGGTGGACTGGTGTG AGGGCAGACCAGGGCCAGGTAGACGGGGCTGTTTGGTGCCTGAAGGATGGCAGACGCCTGGTGTCAGGAGGGGCCGCCACCAAGGAGCAG CAGCTGGGGCAGAGGAGCTGGGGTCAGGGGCCACCCCTCTCTGCCGATCTCCCTGCCTGGGCTGGCTGTGAGGCCACCTTTGTCCCAGGC CCAGCCTCAAGGCAAGGAGGGCGCTTCACTGAGGTGTGAATTGTACGTACAGGCTTTTTATATACCAAAAGTATTTTTTGACTAGACCAT TCAAAGCTACCCGAACTATGTTGGAAATTTTTTTTTTCTCATTAAAATACAGGCCCTTAGGCTCTATTTTTCATGTATGAGTCGTGTGTA ATTTATGTAAAAATGTGTGTACAGACTCACTGATGCAGCACTGTAGCCCATCACCTTGGAGCACTGACTGTACATAGTGTGGTGAAGAAA AGTGAACGCCCTTGTAGAGCAGCCCGACCACAGGAGCATGGCCGCTGCCAGCCCAGACGCTGCTGACGCTGTGTAAATGTGCACAATAAA >1515_1515_4_ACSL5-PPP1R13B_ACSL5_chr10_114186117_ENST00000369410_PPP1R13B_chr14_104212890_ENST00000202556_length(amino acids)=1162AA_BP=395 MLFPGASIVPECWLLVLIQNLGKEHFRKPVPPSPEDLSVICFTSGTTGDPKGAMITHQNIVSNAAAFLKCVEHAYEPTPDDVAISYLPLA HMFERIVQAVVYSCGARVGFFQGDIRLLADDMKTLKPTLFPAVPRLLNRIYDKVQNEAKTPLKKFLLKLAVSSKFKELQKGIIRHDSFWD KLIFAKIQDSLGGRVRVIVTGAAPMSTSVMTFFRAAMGCQVYEAYGQTECTGGCTFTLPGDWTSGHVGVPLACNYVKLEDVADMNYFTVN NEGEVCIKGTNVFKGYLKDPEKTQEALDSDGWLHTGDIGRWLPNGTLKIIDRKKNIFKLAQGEYIAPEKIENIYNRSQPVLQIFVHGESL RSSLVGVVVPDTDVLPSFAAKLGVKGSFEELCQNQLNRVNGTSSPQSPLSTSGRVAAVGPYIQVPSAGSFPVLGDPIKPQSLSIASNAAH GRSKSANDGNWPTLKQNSSSSVKPVQVAGADWKDPSVEGSVKQGTVSSQPVPFSALGPTEKPGIEIGKVPPPIPGVGKQLPPSYGTYPSP TPLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTLLPATGSTPQPGSSQQIQQRISVPPSPTYPPAGPPAFPAGDSKPELPLTVAIRPFLA DKGSRPQSPRKGPQTVNSSSIYSMYLQQATPPKNYQPAAHSALNKSVKAVYGKPVLPSGSTSPSPLPFLHGSLSTGTPQPQPPSESTEKE PEQDGPAAPADGSTVESLPRPLSPTKLTPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSSITEPEGPGGPNIQKLLYQRFNTLAGGME GTPFYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAPLPAEPAPSSDANDNELPSPEPEELICPQTTHQTAEPAEDNNNNVATVP TTEQIPSPVAEAPSPGEEQVPPAPLPPASHPPATSTNKRTNLKKPNSERTGHGLRVRFNPLALLLDASLEGEFDLVQRIIYEVEDPSKPN DEGITPLHNAVCAGHHHIVKFLLDFGVNVNAADSDGWTPLHCAASCNSVHLCKQLVESGAAIFASTISDIETAADKCEEMEEGYIQCSQF -------------------------------------------------------------- >1515_1515_5_ACSL5-PPP1R13B_ACSL5_chr10_114186117_ENST00000393081_PPP1R13B_chr14_104212890_ENST00000202556_length(transcript)=5852nt_BP=2146nt GCCAGAGGATGGAATGCCACAGGCCCCACTTCGTCTCCCAGCCCTTCATCTTTCTTCCATGTCCAAAGGCGGCTCCCCAGAGGCCAAGGG CTCAGCTCTTGTGTTCTCTGAGACTGTGGCACAGCTCACCCTGGCTTCCTTAGTAGGAAGCTTTTAAGAACTGCTCTGTAGAAAGAACAA ACCCTAATCTAGCTCCAGCAAAGAGCCAGGATCATGCTGAACTTCCTGTGAGCCTTCGTGGGGGATCGAGGCTGGAGAAAGTGCTGCTTC ATTCTGAGGTCTGAATTTCCTGCTGCTGTTCACAAAGATGCTTTTTATCTTTAACTTTTTGTTTTCCCCACTTCCGACCCCGGCGTTGAT CTGCATCCTGACATTTGGAGCTGCCATCTTCTTGTGGCTGATCACCAGACCTCAACCCGTCTTACCTCTTCTTGACCTGAACAATCAGTC TGTGGGAATTGAGGGAGGAGCACGGAAGGGGGTTTCCCAGAAGAACAATGACCTAACAAGTTGCTGCTTCTCAGATGCCAAGACTATGTA TGAGGTTTTCCAAAGAGGACTCGCTGTGTCTGACAATGGGCCCTGCTTGGGATATAGAAAACCAAACCAGCCCTACAGATGGCTATCTTA CAAACAGGTGTCTGATAGAGCAGAGTACCTGGGTTCCTGTCTCTTGCATAAAGGTTATAAATCATCACCAGACCAGTTTGTCGGCATCTT TGCTCAGAATAGGCCAGAGTGGATCATCTCCGAATTGGCTTGTTACACGTACTCTATGGTAGCTGTACCTCTGTATGACACCTTGGGACC AGAAGCCATCGTACATATTGTCAACAAGGCTGATATCGCCATGGTGATCTGTGACACACCCCAAAAGGCATTGGTGCTGATAGGGAATGT AGAGAAAGGCTTCACCCCGAGCCTGAAGGTGATCATCCTTATGGACCCCTTTGATGATGACCTGAAGCAAAGAGGGGAGAAGAGTGGAAT TGAGATCTTATCCCTATATGATGCTGAGAACCTAGGCAAAGAGCACTTCAGAAAACCTGTGCCTCCTAGCCCAGAAGACCTGAGCGTCAT CTGCTTCACCAGTGGGACCACAGGTGACCCCAAAGGAGCCATGATAACCCATCAAAATATTGTTTCAAATGCTGCTGCCTTTCTCAAATG TGTGGAGCATGCTTATGAGCCCACTCCTGATGATGTGGCCATATCCTACCTCCCTCTGGCTCATATGTTTGAGAGGATTGTACAGGCTGT TGTGTACAGCTGTGGAGCCAGAGTTGGATTCTTCCAAGGGGATATTCGGTTGCTGGCTGACGACATGAAGACTTTGAAGCCCACATTGTT TCCCGCGGTGCCTCGACTCCTTAACAGGATCTACGATAAGGTACAAAATGAGGCCAAGACACCCTTGAAGAAGTTCTTGTTGAAGCTGGC TGTTTCCAGTAAATTCAAAGAGCTTCAAAAGGGTATCATCAGGCATGATAGTTTCTGGGACAAGCTCATCTTTGCAAAGATCCAGGACAG CCTGGGCGGAAGGGTTCGTGTAATTGTCACTGGAGCTGCCCCCATGTCCACTTCAGTCATGACATTCTTCCGGGCAGCAATGGGATGTCA GGTGTATGAAGCTTATGGTCAAACAGAATGCACAGGTGGCTGTACATTTACATTACCTGGGGACTGGACATCAGGTCACGTTGGGGTGCC CCTGGCTTGCAATTACGTGAAGCTGGAAGATGTGGCTGACATGAACTACTTTACAGTGAATAATGAAGGAGAGGTCTGCATCAAGGGTAC AAACGTGTTCAAAGGATACCTGAAGGACCCTGAGAAGACACAGGAAGCCCTGGACAGTGATGGCTGGCTTCACACAGGAGACATTGGTCG CTGGCTCCCGAATGGAACTCTGAAGATCATCGACCGTAAAAAGAACATTTTCAAGCTGGCCCAAGGAGAATACATTGCACCAGAGAAGAT AGAAAATATCTACAACAGGAGTCAACCAGTGTTACAAATTTTTGTACACGGGGAGAGCTTACGGTCATCCTTAGTAGGAGTGGTGGTTCC TGACACAGATGTACTTCCCTCATTTGCAGCCAAGCTTGGGGTGAAGGGCTCCTTTGAGGAACTGTGCCAAAACCAACTGAACCGTGTGAA TGGCACGTCATCACCACAGTCCCCTCTGAGCACATCGGGCAGGGTCGCTGCTGTGGGGCCTTATATCCAGGTTCCCAGTGCCGGAAGCTT TCCTGTGCTGGGGGACCCTATAAAGCCCCAGTCTCTCAGTATTGCCTCAAATGCTGCTCATGGAAGATCCAAATCCGCTAATGATGGAAA CTGGCCAACATTAAAACAGAATTCTAGCTCTTCCGTGAAACCAGTGCAGGTGGCCGGTGCAGACTGGAAGGATCCGAGCGTGGAGGGGTC TGTCAAGCAGGGCACTGTCTCCAGCCAGCCTGTGCCCTTCTCAGCACTGGGACCCACGGAGAAGCCGGGCATCGAGATTGGTAAAGTGCC ACCTCCCATCCCGGGTGTAGGCAAGCAGCTGCCTCCAAGCTATGGGACATACCCAAGTCCTACACCTCTGGGTCCTGGGTCGACAAGCTC CCTGGAAAGGAGGAAGGAAGGCAGCTTGCCCAGGCCCAGTGCAGGCCTGCCAAGTCGACAGAGGCCCACCCTGCTGCCCGCCACAGGCAG CACCCCCCAGCCAGGCTCCTCACAACAGATTCAGCAGAGGATTTCCGTACCGCCAAGTCCCACGTACCCGCCAGCGGGACCACCTGCATT TCCAGCTGGGGACAGCAAGCCTGAACTCCCACTGACAGTGGCCATTAGGCCTTTCCTGGCTGATAAAGGGTCAAGGCCACAGTCTCCCAG GAAAGGACCCCAGACAGTGAATTCAAGTTCCATATACTCCATGTACCTCCAGCAAGCCACACCACCTAAGAATTACCAGCCGGCAGCACA CAGCGCCTTAAATAAGTCAGTTAAAGCAGTGTATGGTAAGCCCGTTTTACCTTCGGGTTCAACCTCTCCATCGCCGCTGCCGTTTCTTCA CGGGTCACTGTCCACGGGCACACCACAGCCTCAGCCACCTTCAGAAAGTACTGAGAAAGAGCCTGAGCAGGATGGCCCCGCCGCCCCCGC AGATGGCAGCACCGTGGAGAGCCTGCCACGGCCACTCAGCCCCACCAAGCTCACGCCCATCGTGCATTCGCCACTGCGCTACCAGAGTGA TGCAGACCTGGAGGCCCTCCGCAGGAAGCTGGCCAACGCGCCCCGGCCCCTGAAAAAGCGCAGCTCCATCACAGAGCCCGAGGGCCCCGG CGGGCCCAACATCCAGAAGCTGCTGTACCAGCGCTTCAACACCCTGGCCGGTGGCATGGAGGGCACCCCTTTCTACCAGCCCAGCCCCTC CCAGGACTTCATGGGCACCTTGGCCGATGTGGACAATGGAAACACCAATGCCAATGGAAACCTGGAAGAGCTCCCCCCTGCCCAGCCCAC AGCCCCACTCCCCGCTGAGCCTGCCCCGTCATCAGATGCCAATGATAATGAGTTACCTTCCCCCGAACCAGAGGAGCTCATCTGTCCCCA AACCACCCACCAAACTGCCGAGCCGGCAGAGGACAATAACAACAACGTGGCCACGGTCCCCACCACGGAGCAGATCCCGAGTCCTGTGGC TGAGGCCCCATCTCCAGGGGAAGAGCAGGTCCCTCCAGCACCTCTTCCCCCTGCCAGCCACCCTCCTGCCACCTCCACGAACAAGCGGAC CAACTTGAAGAAGCCCAACTCGGAGCGGACGGGGCACGGGCTGAGAGTCCGGTTTAACCCCCTGGCACTGCTCCTAGACGCGTCTCTGGA AGGAGAGTTCGATCTGGTGCAGAGGATCATCTATGAGGTGGAAGATCCCAGCAAGCCCAACGACGAAGGGATCACCCCACTGCACAACGC CGTCTGCGCCGGCCACCATCACATCGTGAAGTTCCTGCTGGATTTTGGTGTCAACGTGAATGCTGCTGATAGTGATGGATGGACGCCGCT GCACTGCGCTGCCTCTTGTAACAGCGTTCACCTCTGCAAACAGCTGGTGGAGAGTGGTGCCGCCATTTTTGCCTCAACCATAAGCGACAT TGAAACTGCTGCAGACAAGTGTGAGGAGATGGAGGAAGGCTACATCCAGTGCTCCCAGTTTCTATATGGGGTGCAGGAAAAGCTGGGTGT GATGAACAAAGGTGTGGCGTATGCTCTGTGGGACTACGAGGCCCAGAACAGTGACGAGCTGTCCTTCCACGAAGGGGACGCCCTCACCAT CCTGAGGCGCAAGGACGAAAGCGAGACTGAGTGGTGGTGGGCTCGCCTTGGAGACCGGGAGGGCTATGTGCCCAAAAACCTGCTGGGGCT GTATCCACGGATCAAACCCCGACAGCGAACACTCGCCTGAACTTCCTTTTGGAGCACCGCATGGTCTTGCCAGCTACCAGGAGCCACTTA AGAGATTATTGTGCTGTTTTCCAGGAAAGCTGCAGCTAGAAAATGGTCTTAATGGTGCTCACTTTAGCAGACAGCGTCCACAATGTGAAT CCTACAGTTTCCAGGTGAGGCCCTTTCTCCAGTTTGCCCATTAACTGGGAGAGGTACTTTCGCCTCCAAGGACTGAATTTTGCCAATTAC TATAAATCCAAATAAATACCCACTTTCAAAACACCCACCCCTCTTGCCATTAAGAAGTCCCATAACCCCCGGTTGGTTGCCAGTGAAGAC AGAAGCTCTTACTGACTTGGCCCCGAGGCCATCACCCCCTCCAGCAGTGAACACTGTCCGCCGCTGTGAGGCCTGCTCCCCTGCGACCGC CCTGCCCCCCGTCACCGAATCGGACACTCATCCTTTCTCACACTTCCCACACATGATCCTTCTTCCCTTCATCACCAAAGGAGCCTCTGT ATGGAAACATGTCCAGTGTTGCTGCCCAGTGTGTATGCCTCCCAGTACCCACTCTGCTCGGCCGCCTTGGGGGTTCCGCTTCCTGTTCCA GTTCACCTAAAGGCTGATTGTGCAGGCCCAGCACTGTGGCTGGACTGCCGCGCCACGGGCACCAGGACCCCTAAGACCAAGTGACAACTG GGAGAGCCTCAGCATATACTCTTCTCCTCCGATCTCACAGCCTGTCATGCTGCTCAGTGTGGTTCTCACCCCTGCAAGCTCAAATTCAGT TCCCTGAATGGAGTCAGGTGCTGGAGGCCGTGGCAGCGGAGGGTGGTTGGGGTTGGGGCTGGGGGTGGACTGGTGTGAGGGCAGACCAGG GCCAGGTAGACGGGGCTGTTTGGTGCCTGAAGGATGGCAGACGCCTGGTGTCAGGAGGGGCCGCCACCAAGGAGCAGCAGCTGGGGCAGA GGAGCTGGGGTCAGGGGCCACCCCTCTCTGCCGATCTCCCTGCCTGGGCTGGCTGTGAGGCCACCTTTGTCCCAGGCCCAGCCTCAAGGC AAGGAGGGCGCTTCACTGAGGTGTGAATTGTACGTACAGGCTTTTTATATACCAAAAGTATTTTTTGACTAGACCATTCAAAGCTACCCG AACTATGTTGGAAATTTTTTTTTTCTCATTAAAATACAGGCCCTTAGGCTCTATTTTTCATGTATGAGTCGTGTGTAATTTATGTAAAAA TGTGTGTACAGACTCACTGATGCAGCACTGTAGCCCATCACCTTGGAGCACTGACTGTACATAGTGTGGTGAAGAAAAGTGAACGCCCTT GTAGAGCAGCCCGACCACAGGAGCATGGCCGCTGCCAGCCCAGACGCTGCTGACGCTGTGTAAATGTGCACAATAAACCCGTCTCACCCC >1515_1515_5_ACSL5-PPP1R13B_ACSL5_chr10_114186117_ENST00000393081_PPP1R13B_chr14_104212890_ENST00000202556_length(amino acids)=1389AA_BP=622 MNFLLLFTKMLFIFNFLFSPLPTPALICILTFGAAIFLWLITRPQPVLPLLDLNNQSVGIEGGARKGVSQKNNDLTSCCFSDAKTMYEVF QRGLAVSDNGPCLGYRKPNQPYRWLSYKQVSDRAEYLGSCLLHKGYKSSPDQFVGIFAQNRPEWIISELACYTYSMVAVPLYDTLGPEAI VHIVNKADIAMVICDTPQKALVLIGNVEKGFTPSLKVIILMDPFDDDLKQRGEKSGIEILSLYDAENLGKEHFRKPVPPSPEDLSVICFT SGTTGDPKGAMITHQNIVSNAAAFLKCVEHAYEPTPDDVAISYLPLAHMFERIVQAVVYSCGARVGFFQGDIRLLADDMKTLKPTLFPAV PRLLNRIYDKVQNEAKTPLKKFLLKLAVSSKFKELQKGIIRHDSFWDKLIFAKIQDSLGGRVRVIVTGAAPMSTSVMTFFRAAMGCQVYE AYGQTECTGGCTFTLPGDWTSGHVGVPLACNYVKLEDVADMNYFTVNNEGEVCIKGTNVFKGYLKDPEKTQEALDSDGWLHTGDIGRWLP NGTLKIIDRKKNIFKLAQGEYIAPEKIENIYNRSQPVLQIFVHGESLRSSLVGVVVPDTDVLPSFAAKLGVKGSFEELCQNQLNRVNGTS SPQSPLSTSGRVAAVGPYIQVPSAGSFPVLGDPIKPQSLSIASNAAHGRSKSANDGNWPTLKQNSSSSVKPVQVAGADWKDPSVEGSVKQ GTVSSQPVPFSALGPTEKPGIEIGKVPPPIPGVGKQLPPSYGTYPSPTPLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTLLPATGSTPQ PGSSQQIQQRISVPPSPTYPPAGPPAFPAGDSKPELPLTVAIRPFLADKGSRPQSPRKGPQTVNSSSIYSMYLQQATPPKNYQPAAHSAL NKSVKAVYGKPVLPSGSTSPSPLPFLHGSLSTGTPQPQPPSESTEKEPEQDGPAAPADGSTVESLPRPLSPTKLTPIVHSPLRYQSDADL EALRRKLANAPRPLKKRSSITEPEGPGGPNIQKLLYQRFNTLAGGMEGTPFYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAPL PAEPAPSSDANDNELPSPEPEELICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEAPSPGEEQVPPAPLPPASHPPATSTNKRTNLK KPNSERTGHGLRVRFNPLALLLDASLEGEFDLVQRIIYEVEDPSKPNDEGITPLHNAVCAGHHHIVKFLLDFGVNVNAADSDGWTPLHCA ASCNSVHLCKQLVESGAAIFASTISDIETAADKCEEMEEGYIQCSQFLYGVQEKLGVMNKGVAYALWDYEAQNSDELSFHEGDALTILRR -------------------------------------------------------------- >1515_1515_6_ACSL5-PPP1R13B_ACSL5_chr10_114186117_ENST00000433418_PPP1R13B_chr14_104212890_ENST00000202556_length(transcript)=5825nt_BP=2119nt TAAAACCAGGAAGTGAAGTCCCCGAGCACGTTAGAAAGCCTGACATGGCCTGACTCGGGACAGCTCAGAGCAGGGCAGAACTGGGGACAC TCTGGGCCGGCCTTCTGCCTGCATGGACGCTCTGAAGCCACCCTGTCTCTGGAGGAACCACGAGCGAGGGAAGAAGGACAGGGACTCGTG TGGCAGGAAGAACTCAGAGCCGGGAAGCCCCCATTCACTAGAAGCACTGAGAGATGCGGCCCCCTCGCAGGGTCTGAATTTCCTGCTGCT GTTCACAAAGATGCTTTTTATCTTTAACTTTTTGTTTTCCCCACTTCCGACCCCGGCGTTGATCTGCATCCTGACATTTGGAGCTGCCAT CTTCTTGTGGCTGATCACCAGACCTCAACCCGTCTTACCTCTTCTTGACCTGAACAATCAGTCTGTGGGAATTGAGGGAGGAGCACGGAA GGGGGTTTCCCAGAAGAACAATGACCTAACAAGTTGCTGCTTCTCAGATGCCAAGACTATGTATGAGGTTTTCCAAAGAGGACTCGCTGT GTCTGACAATGGGCCCTGCTTGGGATATAGAAAACCAAACCAGCCCTACAGATGGCTATCTTACAAACAGGTGTCTGATAGAGCAGAGTA CCTGGGTTCCTGTCTCTTGCATAAAGGTTATAAATCATCACCAGACCAGTTTGTCGGCATCTTTGCTCAGAATAGGCCAGAGTGGATCAT CTCCGAATTGGCTTGTTACACGTACTCTATGGTAGCTGTACCTCTGTATGACACCTTGGGACCAGAAGCCATCGTACATATTGTCAACAA GGCTGATATCGCCATGGTGATCTGTGACACACCCCAAAAGGCATTGGTGCTGATAGGGAATGTAGAGAAAGGCTTCACCCCGAGCCTGAA GGTGATCATCCTTATGGACCCCTTTGATGATGACCTGAAGCAAAGAGGGGAGAAGAGTGGAATTGAGATCTTATCCCTATATGATGCTGA GAACCTAGGCAAAGAGCACTTCAGAAAACCTGTGCCTCCTAGCCCAGAAGACCTGAGCGTCATCTGCTTCACCAGTGGGACCACAGGTGA CCCCAAAGGAGCCATGATAACCCATCAAAATATTGTTTCAAATGCTGCTGCCTTTCTCAAATGTGTGGAGCATGCTTATGAGCCCACTCC TGATGATGTGGCCATATCCTACCTCCCTCTGGCTCATATGTTTGAGAGGATTGTACAGGCTGTTGTGTACAGCTGTGGAGCCAGAGTTGG ATTCTTCCAAGGGGATATTCGGTTGCTGGCTGACGACATGAAGACTTTGAAGCCCACATTGTTTCCCGCGGTGCCTCGACTCCTTAACAG GATCTACGATAAGGTACAAAATGAGGCCAAGACACCCTTGAAGAAGTTCTTGTTGAAGCTGGCTGTTTCCAGTAAATTCAAAGAGCTTCA AAAGGGTATCATCAGGCATGATAGTTTCTGGGACAAGCTCATCTTTGCAAAGATCCAGGACAGCCTGGGCGGAAGGGTTCGTGTAATTGT CACTGGAGCTGCCCCCATGTCCACTTCAGTCATGACATTCTTCCGGGCAGCAATGGGATGTCAGGTGTATGAAGCTTATGGTCAAACAGA ATGCACAGGTGGCTGTACATTTACATTACCTGGGGACTGGACATCAGGTCACGTTGGGGTGCCCCTGGCTTGCAATTACGTGAAGCTGGA AGATGTGGCTGACATGAACTACTTTACAGTGAATAATGAAGGAGAGGTCTGCATCAAGGGTACAAACGTGTTCAAAGGATACCTGAAGGA CCCTGAGAAGACACAGGAAGCCCTGGACAGTGATGGCTGGCTTCACACAGGAGACATTGGTCGCTGGCTCCCGAATGGAACTCTGAAGAT CATCGACCGTAAAAAGAACATTTTCAAGCTGGCCCAAGGAGAATACATTGCACCAGAGAAGATAGAAAATATCTACAACAGGAGTCAACC AGTGTTACAAATTTTTGTACACGGGGAGAGCTTACGGTCATCCTTAGTAGGAGTGGTGGTTCCTGACACAGATGTACTTCCCTCATTTGC AGCCAAGCTTGGGGTGAAGGGCTCCTTTGAGGAACTGTGCCAAAACCAACTGAACCGTGTGAATGGCACGTCATCACCACAGTCCCCTCT GAGCACATCGGGCAGGGTCGCTGCTGTGGGGCCTTATATCCAGGTTCCCAGTGCCGGAAGCTTTCCTGTGCTGGGGGACCCTATAAAGCC CCAGTCTCTCAGTATTGCCTCAAATGCTGCTCATGGAAGATCCAAATCCGCTAATGATGGAAACTGGCCAACATTAAAACAGAATTCTAG CTCTTCCGTGAAACCAGTGCAGGTGGCCGGTGCAGACTGGAAGGATCCGAGCGTGGAGGGGTCTGTCAAGCAGGGCACTGTCTCCAGCCA GCCTGTGCCCTTCTCAGCACTGGGACCCACGGAGAAGCCGGGCATCGAGATTGGTAAAGTGCCACCTCCCATCCCGGGTGTAGGCAAGCA GCTGCCTCCAAGCTATGGGACATACCCAAGTCCTACACCTCTGGGTCCTGGGTCGACAAGCTCCCTGGAAAGGAGGAAGGAAGGCAGCTT GCCCAGGCCCAGTGCAGGCCTGCCAAGTCGACAGAGGCCCACCCTGCTGCCCGCCACAGGCAGCACCCCCCAGCCAGGCTCCTCACAACA GATTCAGCAGAGGATTTCCGTACCGCCAAGTCCCACGTACCCGCCAGCGGGACCACCTGCATTTCCAGCTGGGGACAGCAAGCCTGAACT CCCACTGACAGTGGCCATTAGGCCTTTCCTGGCTGATAAAGGGTCAAGGCCACAGTCTCCCAGGAAAGGACCCCAGACAGTGAATTCAAG TTCCATATACTCCATGTACCTCCAGCAAGCCACACCACCTAAGAATTACCAGCCGGCAGCACACAGCGCCTTAAATAAGTCAGTTAAAGC AGTGTATGGTAAGCCCGTTTTACCTTCGGGTTCAACCTCTCCATCGCCGCTGCCGTTTCTTCACGGGTCACTGTCCACGGGCACACCACA GCCTCAGCCACCTTCAGAAAGTACTGAGAAAGAGCCTGAGCAGGATGGCCCCGCCGCCCCCGCAGATGGCAGCACCGTGGAGAGCCTGCC ACGGCCACTCAGCCCCACCAAGCTCACGCCCATCGTGCATTCGCCACTGCGCTACCAGAGTGATGCAGACCTGGAGGCCCTCCGCAGGAA GCTGGCCAACGCGCCCCGGCCCCTGAAAAAGCGCAGCTCCATCACAGAGCCCGAGGGCCCCGGCGGGCCCAACATCCAGAAGCTGCTGTA CCAGCGCTTCAACACCCTGGCCGGTGGCATGGAGGGCACCCCTTTCTACCAGCCCAGCCCCTCCCAGGACTTCATGGGCACCTTGGCCGA TGTGGACAATGGAAACACCAATGCCAATGGAAACCTGGAAGAGCTCCCCCCTGCCCAGCCCACAGCCCCACTCCCCGCTGAGCCTGCCCC GTCATCAGATGCCAATGATAATGAGTTACCTTCCCCCGAACCAGAGGAGCTCATCTGTCCCCAAACCACCCACCAAACTGCCGAGCCGGC AGAGGACAATAACAACAACGTGGCCACGGTCCCCACCACGGAGCAGATCCCGAGTCCTGTGGCTGAGGCCCCATCTCCAGGGGAAGAGCA GGTCCCTCCAGCACCTCTTCCCCCTGCCAGCCACCCTCCTGCCACCTCCACGAACAAGCGGACCAACTTGAAGAAGCCCAACTCGGAGCG GACGGGGCACGGGCTGAGAGTCCGGTTTAACCCCCTGGCACTGCTCCTAGACGCGTCTCTGGAAGGAGAGTTCGATCTGGTGCAGAGGAT CATCTATGAGGTGGAAGATCCCAGCAAGCCCAACGACGAAGGGATCACCCCACTGCACAACGCCGTCTGCGCCGGCCACCATCACATCGT GAAGTTCCTGCTGGATTTTGGTGTCAACGTGAATGCTGCTGATAGTGATGGATGGACGCCGCTGCACTGCGCTGCCTCTTGTAACAGCGT TCACCTCTGCAAACAGCTGGTGGAGAGTGGTGCCGCCATTTTTGCCTCAACCATAAGCGACATTGAAACTGCTGCAGACAAGTGTGAGGA GATGGAGGAAGGCTACATCCAGTGCTCCCAGTTTCTATATGGGGTGCAGGAAAAGCTGGGTGTGATGAACAAAGGTGTGGCGTATGCTCT GTGGGACTACGAGGCCCAGAACAGTGACGAGCTGTCCTTCCACGAAGGGGACGCCCTCACCATCCTGAGGCGCAAGGACGAAAGCGAGAC TGAGTGGTGGTGGGCTCGCCTTGGAGACCGGGAGGGCTATGTGCCCAAAAACCTGCTGGGGCTGTATCCACGGATCAAACCCCGACAGCG AACACTCGCCTGAACTTCCTTTTGGAGCACCGCATGGTCTTGCCAGCTACCAGGAGCCACTTAAGAGATTATTGTGCTGTTTTCCAGGAA AGCTGCAGCTAGAAAATGGTCTTAATGGTGCTCACTTTAGCAGACAGCGTCCACAATGTGAATCCTACAGTTTCCAGGTGAGGCCCTTTC TCCAGTTTGCCCATTAACTGGGAGAGGTACTTTCGCCTCCAAGGACTGAATTTTGCCAATTACTATAAATCCAAATAAATACCCACTTTC AAAACACCCACCCCTCTTGCCATTAAGAAGTCCCATAACCCCCGGTTGGTTGCCAGTGAAGACAGAAGCTCTTACTGACTTGGCCCCGAG GCCATCACCCCCTCCAGCAGTGAACACTGTCCGCCGCTGTGAGGCCTGCTCCCCTGCGACCGCCCTGCCCCCCGTCACCGAATCGGACAC TCATCCTTTCTCACACTTCCCACACATGATCCTTCTTCCCTTCATCACCAAAGGAGCCTCTGTATGGAAACATGTCCAGTGTTGCTGCCC AGTGTGTATGCCTCCCAGTACCCACTCTGCTCGGCCGCCTTGGGGGTTCCGCTTCCTGTTCCAGTTCACCTAAAGGCTGATTGTGCAGGC CCAGCACTGTGGCTGGACTGCCGCGCCACGGGCACCAGGACCCCTAAGACCAAGTGACAACTGGGAGAGCCTCAGCATATACTCTTCTCC TCCGATCTCACAGCCTGTCATGCTGCTCAGTGTGGTTCTCACCCCTGCAAGCTCAAATTCAGTTCCCTGAATGGAGTCAGGTGCTGGAGG CCGTGGCAGCGGAGGGTGGTTGGGGTTGGGGCTGGGGGTGGACTGGTGTGAGGGCAGACCAGGGCCAGGTAGACGGGGCTGTTTGGTGCC TGAAGGATGGCAGACGCCTGGTGTCAGGAGGGGCCGCCACCAAGGAGCAGCAGCTGGGGCAGAGGAGCTGGGGTCAGGGGCCACCCCTCT CTGCCGATCTCCCTGCCTGGGCTGGCTGTGAGGCCACCTTTGTCCCAGGCCCAGCCTCAAGGCAAGGAGGGCGCTTCACTGAGGTGTGAA TTGTACGTACAGGCTTTTTATATACCAAAAGTATTTTTTGACTAGACCATTCAAAGCTACCCGAACTATGTTGGAAATTTTTTTTTTCTC ATTAAAATACAGGCCCTTAGGCTCTATTTTTCATGTATGAGTCGTGTGTAATTTATGTAAAAATGTGTGTACAGACTCACTGATGCAGCA CTGTAGCCCATCACCTTGGAGCACTGACTGTACATAGTGTGGTGAAGAAAAGTGAACGCCCTTGTAGAGCAGCCCGACCACAGGAGCATG >1515_1515_6_ACSL5-PPP1R13B_ACSL5_chr10_114186117_ENST00000433418_PPP1R13B_chr14_104212890_ENST00000202556_length(amino acids)=1457AA_BP=690 MTRDSSEQGRTGDTLGRPSACMDALKPPCLWRNHERGKKDRDSCGRKNSEPGSPHSLEALRDAAPSQGLNFLLLFTKMLFIFNFLFSPLP TPALICILTFGAAIFLWLITRPQPVLPLLDLNNQSVGIEGGARKGVSQKNNDLTSCCFSDAKTMYEVFQRGLAVSDNGPCLGYRKPNQPY RWLSYKQVSDRAEYLGSCLLHKGYKSSPDQFVGIFAQNRPEWIISELACYTYSMVAVPLYDTLGPEAIVHIVNKADIAMVICDTPQKALV LIGNVEKGFTPSLKVIILMDPFDDDLKQRGEKSGIEILSLYDAENLGKEHFRKPVPPSPEDLSVICFTSGTTGDPKGAMITHQNIVSNAA AFLKCVEHAYEPTPDDVAISYLPLAHMFERIVQAVVYSCGARVGFFQGDIRLLADDMKTLKPTLFPAVPRLLNRIYDKVQNEAKTPLKKF LLKLAVSSKFKELQKGIIRHDSFWDKLIFAKIQDSLGGRVRVIVTGAAPMSTSVMTFFRAAMGCQVYEAYGQTECTGGCTFTLPGDWTSG HVGVPLACNYVKLEDVADMNYFTVNNEGEVCIKGTNVFKGYLKDPEKTQEALDSDGWLHTGDIGRWLPNGTLKIIDRKKNIFKLAQGEYI APEKIENIYNRSQPVLQIFVHGESLRSSLVGVVVPDTDVLPSFAAKLGVKGSFEELCQNQLNRVNGTSSPQSPLSTSGRVAAVGPYIQVP SAGSFPVLGDPIKPQSLSIASNAAHGRSKSANDGNWPTLKQNSSSSVKPVQVAGADWKDPSVEGSVKQGTVSSQPVPFSALGPTEKPGIE IGKVPPPIPGVGKQLPPSYGTYPSPTPLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTLLPATGSTPQPGSSQQIQQRISVPPSPTYPPA GPPAFPAGDSKPELPLTVAIRPFLADKGSRPQSPRKGPQTVNSSSIYSMYLQQATPPKNYQPAAHSALNKSVKAVYGKPVLPSGSTSPSP LPFLHGSLSTGTPQPQPPSESTEKEPEQDGPAAPADGSTVESLPRPLSPTKLTPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSSITE PEGPGGPNIQKLLYQRFNTLAGGMEGTPFYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAPLPAEPAPSSDANDNELPSPEPEE LICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEAPSPGEEQVPPAPLPPASHPPATSTNKRTNLKKPNSERTGHGLRVRFNPLALLL DASLEGEFDLVQRIIYEVEDPSKPNDEGITPLHNAVCAGHHHIVKFLLDFGVNVNAADSDGWTPLHCAASCNSVHLCKQLVESGAAIFAS TISDIETAADKCEEMEEGYIQCSQFLYGVQEKLGVMNKGVAYALWDYEAQNSDELSFHEGDALTILRRKDESETEWWWARLGDREGYVPK -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for ACSL5-PPP1R13B |
Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
Hgene | Hgene's interactors | Tgene | Tgene's interactors |
- Retained PPIs in in-frame fusion. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
- Lost PPIs in in-frame fusion. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
- Retained PPIs, but lost function due to frame-shift fusion. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for ACSL5-PPP1R13B |
Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for ACSL5-PPP1R13B |
Diseases associated with fusion partners. (DisGeNet 4.0) |
Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
Hgene | ACSL5 | C0003865 | Arthritis, Adjuvant-Induced | 1 | CTD_human |
Hgene | ACSL5 | C0971858 | Arthritis, Collagen-Induced | 1 | CTD_human |
Hgene | ACSL5 | C0993582 | Arthritis, Experimental | 1 | CTD_human |