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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ACSL5-PPP1R13B (FusionGDB2 ID:HG51703TG23368)

Fusion Gene Summary for ACSL5-PPP1R13B

check button Fusion gene summary
Fusion gene informationFusion gene name: ACSL5-PPP1R13B
Fusion gene ID: hg51703tg23368
HgeneTgene
Gene symbol

ACSL5

PPP1R13B

Gene ID

51703

23368

Gene nameacyl-CoA synthetase long chain family member 5protein phosphatase 1 regulatory subunit 13B
SynonymsACS2|ACS5|FACL5ASPP1|p53BP2-like|p85
Cytomap('ACSL5')('PPP1R13B')

10q25.2

14q32.33

Type of geneprotein-codingprotein-coding
Descriptionlong-chain-fatty-acid--CoA ligase 5FACL5 for fatty acid coenzyme A ligase 5LACS 5arachidonate--CoA ligasefatty acid coenzyme A ligase 5fatty-acid-Coenzyme A ligase, long-chain 5long-chain acyl-CoA synthetase 5long-chain fatty acid coenzyme A ligaseapoptosis-stimulating of p53 protein 1apoptosis-stimulating protein of p53, 1protein phosphatase 1, regulatory (inhibitor) subunit 13B
Modification date2020031320200313
UniProtAcc

Q9ULC5

.
Ensembl transtripts involved in fusion geneENST00000354273, ENST00000354655, 
ENST00000356116, ENST00000369410, 
ENST00000393081, ENST00000433418, 
ENST00000479936, 
Fusion gene scores* DoF score6 X 6 X 5=18010 X 10 X 5=500
# samples 610
** MAII scorelog2(6/180*10)=-1.58496250072116
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(10/500*10)=-2.32192809488736
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ACSL5 [Title/Abstract] AND PPP1R13B [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointACSL5(114186117)-PPP1R13B(104212890), # samples:1
Anticipated loss of major functional domain due to fusion event.ACSL5-PPP1R13B seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ACSL5-PPP1R13B seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ACSL5-PPP1R13B seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
ACSL5-PPP1R13B seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneACSL5

GO:0001676

long-chain fatty acid metabolic process

24269233

TgenePPP1R13B

GO:0072332

intrinsic apoptotic signaling pathway by p53 class mediator

11684014


check buttonFusion gene breakpoints across ACSL5 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across PPP1R13B (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-D7-A4Z0-01AACSL5chr10

114186117

+PPP1R13Bchr14

104212890

-


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Fusion Gene ORF analysis for ACSL5-PPP1R13B

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000354273ENST00000423488ACSL5chr10

114186117

+PPP1R13Bchr14

104212890

-
5CDS-intronENST00000354273ENST00000555391ACSL5chr10

114186117

+PPP1R13Bchr14

104212890

-
5CDS-intronENST00000354655ENST00000423488ACSL5chr10

114186117

+PPP1R13Bchr14

104212890

-
5CDS-intronENST00000354655ENST00000555391ACSL5chr10

114186117

+PPP1R13Bchr14

104212890

-
5CDS-intronENST00000356116ENST00000423488ACSL5chr10

114186117

+PPP1R13Bchr14

104212890

-
5CDS-intronENST00000356116ENST00000555391ACSL5chr10

114186117

+PPP1R13Bchr14

104212890

-
5CDS-intronENST00000369410ENST00000423488ACSL5chr10

114186117

+PPP1R13Bchr14

104212890

-
5CDS-intronENST00000369410ENST00000555391ACSL5chr10

114186117

+PPP1R13Bchr14

104212890

-
5CDS-intronENST00000393081ENST00000423488ACSL5chr10

114186117

+PPP1R13Bchr14

104212890

-
5CDS-intronENST00000393081ENST00000555391ACSL5chr10

114186117

+PPP1R13Bchr14

104212890

-
5CDS-intronENST00000433418ENST00000423488ACSL5chr10

114186117

+PPP1R13Bchr14

104212890

-
5CDS-intronENST00000433418ENST00000555391ACSL5chr10

114186117

+PPP1R13Bchr14

104212890

-
In-frameENST00000354273ENST00000202556ACSL5chr10

114186117

+PPP1R13Bchr14

104212890

-
In-frameENST00000354655ENST00000202556ACSL5chr10

114186117

+PPP1R13Bchr14

104212890

-
In-frameENST00000356116ENST00000202556ACSL5chr10

114186117

+PPP1R13Bchr14

104212890

-
In-frameENST00000369410ENST00000202556ACSL5chr10

114186117

+PPP1R13Bchr14

104212890

-
In-frameENST00000393081ENST00000202556ACSL5chr10

114186117

+PPP1R13Bchr14

104212890

-
In-frameENST00000433418ENST00000202556ACSL5chr10

114186117

+PPP1R13Bchr14

104212890

-
intron-3CDSENST00000479936ENST00000202556ACSL5chr10

114186117

+PPP1R13Bchr14

104212890

-
intron-intronENST00000479936ENST00000423488ACSL5chr10

114186117

+PPP1R13Bchr14

104212890

-
intron-intronENST00000479936ENST00000555391ACSL5chr10

114186117

+PPP1R13Bchr14

104212890

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)
BP loci
(transcript)
Predicted start
(transcript)
Predicted stop
(transcript)
Seq length
(amino acids)
ENST00000354655ACSL5chr10114186117+ENST00000202556PPP1R13Bchr14104212890-5826212025444231389
ENST00000393081ACSL5chr10114186117+ENST00000202556PPP1R13Bchr14104212890-5852214628044491389
ENST00000433418ACSL5chr10114186117+ENST00000202556PPP1R13Bchr14104212890-582521194944221457
ENST00000356116ACSL5chr10114186117+ENST00000202556PPP1R13Bchr14104212890-582521194944221457
ENST00000354273ACSL5chr10114186117+ENST00000202556PPP1R13Bchr14104212890-582421184844211457
ENST00000369410ACSL5chr10114186117+ENST00000202556PPP1R13Bchr14104212890-5055134916436521162

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000354655ENST00000202556ACSL5chr10114186117+PPP1R13Bchr14104212890-0.0008991560.9991009
ENST00000393081ENST00000202556ACSL5chr10114186117+PPP1R13Bchr14104212890-0.0011546240.99884534
ENST00000433418ENST00000202556ACSL5chr10114186117+PPP1R13Bchr14104212890-0.0010209020.9989791
ENST00000356116ENST00000202556ACSL5chr10114186117+PPP1R13Bchr14104212890-0.0010209020.9989791
ENST00000354273ENST00000202556ACSL5chr10114186117+PPP1R13Bchr14104212890-0.0010267650.99897325
ENST00000369410ENST00000202556ACSL5chr10114186117+PPP1R13Bchr14104212890-0.0010526880.9989473

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Fusion Genomic Features for ACSL5-PPP1R13B


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for ACSL5-PPP1R13B


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr10:114186117/chr14:104212890)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ACSL5

Q9ULC5

.
FUNCTION: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation (PubMed:17681178, PubMed:24269233, PubMed:22633490). ACSL5 may activate fatty acids from exogenous sources for the synthesis of triacylglycerol destined for intracellular storage (By similarity). Utilizes a wide range of saturated fatty acids with a preference for C16-C18 unsaturated fatty acids (By similarity). It was suggested that it may also stimulate fatty acid oxidation (By similarity). At the villus tip of the crypt-villus axis of the small intestine may sensitize epithelial cells to apoptosis specifically triggered by the death ligand TRAIL. May have a role in the survival of glioma cells. {ECO:0000250, ECO:0000269|PubMed:17681178, ECO:0000269|PubMed:18806831, ECO:0000269|PubMed:19459852, ECO:0000269|PubMed:22633490, ECO:0000269|PubMed:24269233}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneACSL5chr10:114186117chr14:104212890ENST00000354273+192112_32613684.0TransmembraneHelical%3B Signal-anchor for type III membrane protein
HgeneACSL5chr10:114186117chr14:104212890ENST00000354655+192112_32613684.0TransmembraneHelical%3B Signal-anchor for type III membrane protein
HgeneACSL5chr10:114186117chr14:104212890ENST00000356116+192112_32669740.0TransmembraneHelical%3B Signal-anchor for type III membrane protein
HgeneACSL5chr10:114186117chr14:104212890ENST00000393081+192112_32613684.0TransmembraneHelical%3B Signal-anchor for type III membrane protein
HgeneACSL5chr10:114186117chr14:104212890ENST00000433418+192012_32613660.0TransmembraneHelical%3B Signal-anchor for type III membrane protein
TgenePPP1R13Bchr10:114186117chr14:104212890ENST00000202556717428_8603231091.0Compositional biasNote=Pro-rich
TgenePPP1R13Bchr10:114186117chr14:104212890ENST000002025567171019_10813231091.0DomainSH3
TgenePPP1R13Bchr10:114186117chr14:104212890ENST00000202556717920_9523231091.0RepeatNote=ANK 1
TgenePPP1R13Bchr10:114186117chr14:104212890ENST00000202556717953_9853231091.0RepeatNote=ANK 2

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneACSL5chr10:114186117chr14:104212890ENST00000354273+192133_683613684.0Topological domainCytoplasmic
HgeneACSL5chr10:114186117chr14:104212890ENST00000354655+192133_683613684.0Topological domainCytoplasmic
HgeneACSL5chr10:114186117chr14:104212890ENST00000356116+192133_683669740.0Topological domainCytoplasmic
HgeneACSL5chr10:114186117chr14:104212890ENST00000393081+192133_683613684.0Topological domainCytoplasmic
HgeneACSL5chr10:114186117chr14:104212890ENST00000433418+192033_683613660.0Topological domainCytoplasmic
TgenePPP1R13Bchr10:114186117chr14:104212890ENST00000202556717132_2923231091.0Compositional biasNote=Gln-rich


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Fusion Gene Sequence for ACSL5-PPP1R13B


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>1515_1515_1_ACSL5-PPP1R13B_ACSL5_chr10_114186117_ENST00000354273_PPP1R13B_chr14_104212890_ENST00000202556_length(transcript)=5824nt_BP=2118nt
AAAACCAGGAAGTGAAGTCCCCGAGCACGTTAGAAAGCCTGACATGGCCTGACTCGGGACAGCTCAGAGCAGGGCAGAACTGGGGACACT
CTGGGCCGGCCTTCTGCCTGCATGGACGCTCTGAAGCCACCCTGTCTCTGGAGGAACCACGAGCGAGGGAAGAAGGACAGGGACTCGTGT
GGCAGGAAGAACTCAGAGCCGGGAAGCCCCCATTCACTAGAAGCACTGAGAGATGCGGCCCCCTCGCAGGGTCTGAATTTCCTGCTGCTG
TTCACAAAGATGCTTTTTATCTTTAACTTTTTGTTTTCCCCACTTCCGACCCCGGCGTTGATCTGCATCCTGACATTTGGAGCTGCCATC
TTCTTGTGGCTGATCACCAGACCTCAACCCGTCTTACCTCTTCTTGACCTGAACAATCAGTCTGTGGGAATTGAGGGAGGAGCACGGAAG
GGGGTTTCCCAGAAGAACAATGACCTAACAAGTTGCTGCTTCTCAGATGCCAAGACTATGTATGAGGTTTTCCAAAGAGGACTCGCTGTG
TCTGACAATGGGCCCTGCTTGGGATATAGAAAACCAAACCAGCCCTACAGATGGCTATCTTACAAACAGGTGTCTGATAGAGCAGAGTAC
CTGGGTTCCTGTCTCTTGCATAAAGGTTATAAATCATCACCAGACCAGTTTGTCGGCATCTTTGCTCAGAATAGGCCAGAGTGGATCATC
TCCGAATTGGCTTGTTACACGTACTCTATGGTAGCTGTACCTCTGTATGACACCTTGGGACCAGAAGCCATCGTACATATTGTCAACAAG
GCTGATATCGCCATGGTGATCTGTGACACACCCCAAAAGGCATTGGTGCTGATAGGGAATGTAGAGAAAGGCTTCACCCCGAGCCTGAAG
GTGATCATCCTTATGGACCCCTTTGATGATGACCTGAAGCAAAGAGGGGAGAAGAGTGGAATTGAGATCTTATCCCTATATGATGCTGAG
AACCTAGGCAAAGAGCACTTCAGAAAACCTGTGCCTCCTAGCCCAGAAGACCTGAGCGTCATCTGCTTCACCAGTGGGACCACAGGTGAC
CCCAAAGGAGCCATGATAACCCATCAAAATATTGTTTCAAATGCTGCTGCCTTTCTCAAATGTGTGGAGCATGCTTATGAGCCCACTCCT
GATGATGTGGCCATATCCTACCTCCCTCTGGCTCATATGTTTGAGAGGATTGTACAGGCTGTTGTGTACAGCTGTGGAGCCAGAGTTGGA
TTCTTCCAAGGGGATATTCGGTTGCTGGCTGACGACATGAAGACTTTGAAGCCCACATTGTTTCCCGCGGTGCCTCGACTCCTTAACAGG
ATCTACGATAAGGTACAAAATGAGGCCAAGACACCCTTGAAGAAGTTCTTGTTGAAGCTGGCTGTTTCCAGTAAATTCAAAGAGCTTCAA
AAGGGTATCATCAGGCATGATAGTTTCTGGGACAAGCTCATCTTTGCAAAGATCCAGGACAGCCTGGGCGGAAGGGTTCGTGTAATTGTC
ACTGGAGCTGCCCCCATGTCCACTTCAGTCATGACATTCTTCCGGGCAGCAATGGGATGTCAGGTGTATGAAGCTTATGGTCAAACAGAA
TGCACAGGTGGCTGTACATTTACATTACCTGGGGACTGGACATCAGGTCACGTTGGGGTGCCCCTGGCTTGCAATTACGTGAAGCTGGAA
GATGTGGCTGACATGAACTACTTTACAGTGAATAATGAAGGAGAGGTCTGCATCAAGGGTACAAACGTGTTCAAAGGATACCTGAAGGAC
CCTGAGAAGACACAGGAAGCCCTGGACAGTGATGGCTGGCTTCACACAGGAGACATTGGTCGCTGGCTCCCGAATGGAACTCTGAAGATC
ATCGACCGTAAAAAGAACATTTTCAAGCTGGCCCAAGGAGAATACATTGCACCAGAGAAGATAGAAAATATCTACAACAGGAGTCAACCA
GTGTTACAAATTTTTGTACACGGGGAGAGCTTACGGTCATCCTTAGTAGGAGTGGTGGTTCCTGACACAGATGTACTTCCCTCATTTGCA
GCCAAGCTTGGGGTGAAGGGCTCCTTTGAGGAACTGTGCCAAAACCAACTGAACCGTGTGAATGGCACGTCATCACCACAGTCCCCTCTG
AGCACATCGGGCAGGGTCGCTGCTGTGGGGCCTTATATCCAGGTTCCCAGTGCCGGAAGCTTTCCTGTGCTGGGGGACCCTATAAAGCCC
CAGTCTCTCAGTATTGCCTCAAATGCTGCTCATGGAAGATCCAAATCCGCTAATGATGGAAACTGGCCAACATTAAAACAGAATTCTAGC
TCTTCCGTGAAACCAGTGCAGGTGGCCGGTGCAGACTGGAAGGATCCGAGCGTGGAGGGGTCTGTCAAGCAGGGCACTGTCTCCAGCCAG
CCTGTGCCCTTCTCAGCACTGGGACCCACGGAGAAGCCGGGCATCGAGATTGGTAAAGTGCCACCTCCCATCCCGGGTGTAGGCAAGCAG
CTGCCTCCAAGCTATGGGACATACCCAAGTCCTACACCTCTGGGTCCTGGGTCGACAAGCTCCCTGGAAAGGAGGAAGGAAGGCAGCTTG
CCCAGGCCCAGTGCAGGCCTGCCAAGTCGACAGAGGCCCACCCTGCTGCCCGCCACAGGCAGCACCCCCCAGCCAGGCTCCTCACAACAG
ATTCAGCAGAGGATTTCCGTACCGCCAAGTCCCACGTACCCGCCAGCGGGACCACCTGCATTTCCAGCTGGGGACAGCAAGCCTGAACTC
CCACTGACAGTGGCCATTAGGCCTTTCCTGGCTGATAAAGGGTCAAGGCCACAGTCTCCCAGGAAAGGACCCCAGACAGTGAATTCAAGT
TCCATATACTCCATGTACCTCCAGCAAGCCACACCACCTAAGAATTACCAGCCGGCAGCACACAGCGCCTTAAATAAGTCAGTTAAAGCA
GTGTATGGTAAGCCCGTTTTACCTTCGGGTTCAACCTCTCCATCGCCGCTGCCGTTTCTTCACGGGTCACTGTCCACGGGCACACCACAG
CCTCAGCCACCTTCAGAAAGTACTGAGAAAGAGCCTGAGCAGGATGGCCCCGCCGCCCCCGCAGATGGCAGCACCGTGGAGAGCCTGCCA
CGGCCACTCAGCCCCACCAAGCTCACGCCCATCGTGCATTCGCCACTGCGCTACCAGAGTGATGCAGACCTGGAGGCCCTCCGCAGGAAG
CTGGCCAACGCGCCCCGGCCCCTGAAAAAGCGCAGCTCCATCACAGAGCCCGAGGGCCCCGGCGGGCCCAACATCCAGAAGCTGCTGTAC
CAGCGCTTCAACACCCTGGCCGGTGGCATGGAGGGCACCCCTTTCTACCAGCCCAGCCCCTCCCAGGACTTCATGGGCACCTTGGCCGAT
GTGGACAATGGAAACACCAATGCCAATGGAAACCTGGAAGAGCTCCCCCCTGCCCAGCCCACAGCCCCACTCCCCGCTGAGCCTGCCCCG
TCATCAGATGCCAATGATAATGAGTTACCTTCCCCCGAACCAGAGGAGCTCATCTGTCCCCAAACCACCCACCAAACTGCCGAGCCGGCA
GAGGACAATAACAACAACGTGGCCACGGTCCCCACCACGGAGCAGATCCCGAGTCCTGTGGCTGAGGCCCCATCTCCAGGGGAAGAGCAG
GTCCCTCCAGCACCTCTTCCCCCTGCCAGCCACCCTCCTGCCACCTCCACGAACAAGCGGACCAACTTGAAGAAGCCCAACTCGGAGCGG
ACGGGGCACGGGCTGAGAGTCCGGTTTAACCCCCTGGCACTGCTCCTAGACGCGTCTCTGGAAGGAGAGTTCGATCTGGTGCAGAGGATC
ATCTATGAGGTGGAAGATCCCAGCAAGCCCAACGACGAAGGGATCACCCCACTGCACAACGCCGTCTGCGCCGGCCACCATCACATCGTG
AAGTTCCTGCTGGATTTTGGTGTCAACGTGAATGCTGCTGATAGTGATGGATGGACGCCGCTGCACTGCGCTGCCTCTTGTAACAGCGTT
CACCTCTGCAAACAGCTGGTGGAGAGTGGTGCCGCCATTTTTGCCTCAACCATAAGCGACATTGAAACTGCTGCAGACAAGTGTGAGGAG
ATGGAGGAAGGCTACATCCAGTGCTCCCAGTTTCTATATGGGGTGCAGGAAAAGCTGGGTGTGATGAACAAAGGTGTGGCGTATGCTCTG
TGGGACTACGAGGCCCAGAACAGTGACGAGCTGTCCTTCCACGAAGGGGACGCCCTCACCATCCTGAGGCGCAAGGACGAAAGCGAGACT
GAGTGGTGGTGGGCTCGCCTTGGAGACCGGGAGGGCTATGTGCCCAAAAACCTGCTGGGGCTGTATCCACGGATCAAACCCCGACAGCGA
ACACTCGCCTGAACTTCCTTTTGGAGCACCGCATGGTCTTGCCAGCTACCAGGAGCCACTTAAGAGATTATTGTGCTGTTTTCCAGGAAA
GCTGCAGCTAGAAAATGGTCTTAATGGTGCTCACTTTAGCAGACAGCGTCCACAATGTGAATCCTACAGTTTCCAGGTGAGGCCCTTTCT
CCAGTTTGCCCATTAACTGGGAGAGGTACTTTCGCCTCCAAGGACTGAATTTTGCCAATTACTATAAATCCAAATAAATACCCACTTTCA
AAACACCCACCCCTCTTGCCATTAAGAAGTCCCATAACCCCCGGTTGGTTGCCAGTGAAGACAGAAGCTCTTACTGACTTGGCCCCGAGG
CCATCACCCCCTCCAGCAGTGAACACTGTCCGCCGCTGTGAGGCCTGCTCCCCTGCGACCGCCCTGCCCCCCGTCACCGAATCGGACACT
CATCCTTTCTCACACTTCCCACACATGATCCTTCTTCCCTTCATCACCAAAGGAGCCTCTGTATGGAAACATGTCCAGTGTTGCTGCCCA
GTGTGTATGCCTCCCAGTACCCACTCTGCTCGGCCGCCTTGGGGGTTCCGCTTCCTGTTCCAGTTCACCTAAAGGCTGATTGTGCAGGCC
CAGCACTGTGGCTGGACTGCCGCGCCACGGGCACCAGGACCCCTAAGACCAAGTGACAACTGGGAGAGCCTCAGCATATACTCTTCTCCT
CCGATCTCACAGCCTGTCATGCTGCTCAGTGTGGTTCTCACCCCTGCAAGCTCAAATTCAGTTCCCTGAATGGAGTCAGGTGCTGGAGGC
CGTGGCAGCGGAGGGTGGTTGGGGTTGGGGCTGGGGGTGGACTGGTGTGAGGGCAGACCAGGGCCAGGTAGACGGGGCTGTTTGGTGCCT
GAAGGATGGCAGACGCCTGGTGTCAGGAGGGGCCGCCACCAAGGAGCAGCAGCTGGGGCAGAGGAGCTGGGGTCAGGGGCCACCCCTCTC
TGCCGATCTCCCTGCCTGGGCTGGCTGTGAGGCCACCTTTGTCCCAGGCCCAGCCTCAAGGCAAGGAGGGCGCTTCACTGAGGTGTGAAT
TGTACGTACAGGCTTTTTATATACCAAAAGTATTTTTTGACTAGACCATTCAAAGCTACCCGAACTATGTTGGAAATTTTTTTTTTCTCA
TTAAAATACAGGCCCTTAGGCTCTATTTTTCATGTATGAGTCGTGTGTAATTTATGTAAAAATGTGTGTACAGACTCACTGATGCAGCAC
TGTAGCCCATCACCTTGGAGCACTGACTGTACATAGTGTGGTGAAGAAAAGTGAACGCCCTTGTAGAGCAGCCCGACCACAGGAGCATGG

>1515_1515_1_ACSL5-PPP1R13B_ACSL5_chr10_114186117_ENST00000354273_PPP1R13B_chr14_104212890_ENST00000202556_length(amino acids)=1457AA_BP=690
MTRDSSEQGRTGDTLGRPSACMDALKPPCLWRNHERGKKDRDSCGRKNSEPGSPHSLEALRDAAPSQGLNFLLLFTKMLFIFNFLFSPLP
TPALICILTFGAAIFLWLITRPQPVLPLLDLNNQSVGIEGGARKGVSQKNNDLTSCCFSDAKTMYEVFQRGLAVSDNGPCLGYRKPNQPY
RWLSYKQVSDRAEYLGSCLLHKGYKSSPDQFVGIFAQNRPEWIISELACYTYSMVAVPLYDTLGPEAIVHIVNKADIAMVICDTPQKALV
LIGNVEKGFTPSLKVIILMDPFDDDLKQRGEKSGIEILSLYDAENLGKEHFRKPVPPSPEDLSVICFTSGTTGDPKGAMITHQNIVSNAA
AFLKCVEHAYEPTPDDVAISYLPLAHMFERIVQAVVYSCGARVGFFQGDIRLLADDMKTLKPTLFPAVPRLLNRIYDKVQNEAKTPLKKF
LLKLAVSSKFKELQKGIIRHDSFWDKLIFAKIQDSLGGRVRVIVTGAAPMSTSVMTFFRAAMGCQVYEAYGQTECTGGCTFTLPGDWTSG
HVGVPLACNYVKLEDVADMNYFTVNNEGEVCIKGTNVFKGYLKDPEKTQEALDSDGWLHTGDIGRWLPNGTLKIIDRKKNIFKLAQGEYI
APEKIENIYNRSQPVLQIFVHGESLRSSLVGVVVPDTDVLPSFAAKLGVKGSFEELCQNQLNRVNGTSSPQSPLSTSGRVAAVGPYIQVP
SAGSFPVLGDPIKPQSLSIASNAAHGRSKSANDGNWPTLKQNSSSSVKPVQVAGADWKDPSVEGSVKQGTVSSQPVPFSALGPTEKPGIE
IGKVPPPIPGVGKQLPPSYGTYPSPTPLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTLLPATGSTPQPGSSQQIQQRISVPPSPTYPPA
GPPAFPAGDSKPELPLTVAIRPFLADKGSRPQSPRKGPQTVNSSSIYSMYLQQATPPKNYQPAAHSALNKSVKAVYGKPVLPSGSTSPSP
LPFLHGSLSTGTPQPQPPSESTEKEPEQDGPAAPADGSTVESLPRPLSPTKLTPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSSITE
PEGPGGPNIQKLLYQRFNTLAGGMEGTPFYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAPLPAEPAPSSDANDNELPSPEPEE
LICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEAPSPGEEQVPPAPLPPASHPPATSTNKRTNLKKPNSERTGHGLRVRFNPLALLL
DASLEGEFDLVQRIIYEVEDPSKPNDEGITPLHNAVCAGHHHIVKFLLDFGVNVNAADSDGWTPLHCAASCNSVHLCKQLVESGAAIFAS
TISDIETAADKCEEMEEGYIQCSQFLYGVQEKLGVMNKGVAYALWDYEAQNSDELSFHEGDALTILRRKDESETEWWWARLGDREGYVPK

--------------------------------------------------------------
>1515_1515_2_ACSL5-PPP1R13B_ACSL5_chr10_114186117_ENST00000354655_PPP1R13B_chr14_104212890_ENST00000202556_length(transcript)=5826nt_BP=2120nt
CTTACTGTCAGAGGTTACTACAAGTGTTTGAACAGGTAACTTCTACCTTTGAACTTCTGTTGTGACAGATTCAAAGGTTCCAGGGGAGTG
TGTTGGCCACTCTCAGGACAGTACACAGTAGCTTCGGGTGTGTCCCAGTCAGTCCTAGGAGCTGTGGAAAGAGTAGAAGTGCCTGAATGT
GGTGCTGAATCAATACAGCCAGCTGTGAGGGGAGCACTTCCTGGACCCAGGAAGGGAGAGTCTTCTTCCAAGGTCTGAATTTCCTGCTGC
TGTTCACAAAGATGCTTTTTATCTTTAACTTTTTGTTTTCCCCACTTCCGACCCCGGCGTTGATCTGCATCCTGACATTTGGAGCTGCCA
TCTTCTTGTGGCTGATCACCAGACCTCAACCCGTCTTACCTCTTCTTGACCTGAACAATCAGTCTGTGGGAATTGAGGGAGGAGCACGGA
AGGGGGTTTCCCAGAAGAACAATGACCTAACAAGTTGCTGCTTCTCAGATGCCAAGACTATGTATGAGGTTTTCCAAAGAGGACTCGCTG
TGTCTGACAATGGGCCCTGCTTGGGATATAGAAAACCAAACCAGCCCTACAGATGGCTATCTTACAAACAGGTGTCTGATAGAGCAGAGT
ACCTGGGTTCCTGTCTCTTGCATAAAGGTTATAAATCATCACCAGACCAGTTTGTCGGCATCTTTGCTCAGAATAGGCCAGAGTGGATCA
TCTCCGAATTGGCTTGTTACACGTACTCTATGGTAGCTGTACCTCTGTATGACACCTTGGGACCAGAAGCCATCGTACATATTGTCAACA
AGGCTGATATCGCCATGGTGATCTGTGACACACCCCAAAAGGCATTGGTGCTGATAGGGAATGTAGAGAAAGGCTTCACCCCGAGCCTGA
AGGTGATCATCCTTATGGACCCCTTTGATGATGACCTGAAGCAAAGAGGGGAGAAGAGTGGAATTGAGATCTTATCCCTATATGATGCTG
AGAACCTAGGCAAAGAGCACTTCAGAAAACCTGTGCCTCCTAGCCCAGAAGACCTGAGCGTCATCTGCTTCACCAGTGGGACCACAGGTG
ACCCCAAAGGAGCCATGATAACCCATCAAAATATTGTTTCAAATGCTGCTGCCTTTCTCAAATGTGTGGAGCATGCTTATGAGCCCACTC
CTGATGATGTGGCCATATCCTACCTCCCTCTGGCTCATATGTTTGAGAGGATTGTACAGGCTGTTGTGTACAGCTGTGGAGCCAGAGTTG
GATTCTTCCAAGGGGATATTCGGTTGCTGGCTGACGACATGAAGACTTTGAAGCCCACATTGTTTCCCGCGGTGCCTCGACTCCTTAACA
GGATCTACGATAAGGTACAAAATGAGGCCAAGACACCCTTGAAGAAGTTCTTGTTGAAGCTGGCTGTTTCCAGTAAATTCAAAGAGCTTC
AAAAGGGTATCATCAGGCATGATAGTTTCTGGGACAAGCTCATCTTTGCAAAGATCCAGGACAGCCTGGGCGGAAGGGTTCGTGTAATTG
TCACTGGAGCTGCCCCCATGTCCACTTCAGTCATGACATTCTTCCGGGCAGCAATGGGATGTCAGGTGTATGAAGCTTATGGTCAAACAG
AATGCACAGGTGGCTGTACATTTACATTACCTGGGGACTGGACATCAGGTCACGTTGGGGTGCCCCTGGCTTGCAATTACGTGAAGCTGG
AAGATGTGGCTGACATGAACTACTTTACAGTGAATAATGAAGGAGAGGTCTGCATCAAGGGTACAAACGTGTTCAAAGGATACCTGAAGG
ACCCTGAGAAGACACAGGAAGCCCTGGACAGTGATGGCTGGCTTCACACAGGAGACATTGGTCGCTGGCTCCCGAATGGAACTCTGAAGA
TCATCGACCGTAAAAAGAACATTTTCAAGCTGGCCCAAGGAGAATACATTGCACCAGAGAAGATAGAAAATATCTACAACAGGAGTCAAC
CAGTGTTACAAATTTTTGTACACGGGGAGAGCTTACGGTCATCCTTAGTAGGAGTGGTGGTTCCTGACACAGATGTACTTCCCTCATTTG
CAGCCAAGCTTGGGGTGAAGGGCTCCTTTGAGGAACTGTGCCAAAACCAACTGAACCGTGTGAATGGCACGTCATCACCACAGTCCCCTC
TGAGCACATCGGGCAGGGTCGCTGCTGTGGGGCCTTATATCCAGGTTCCCAGTGCCGGAAGCTTTCCTGTGCTGGGGGACCCTATAAAGC
CCCAGTCTCTCAGTATTGCCTCAAATGCTGCTCATGGAAGATCCAAATCCGCTAATGATGGAAACTGGCCAACATTAAAACAGAATTCTA
GCTCTTCCGTGAAACCAGTGCAGGTGGCCGGTGCAGACTGGAAGGATCCGAGCGTGGAGGGGTCTGTCAAGCAGGGCACTGTCTCCAGCC
AGCCTGTGCCCTTCTCAGCACTGGGACCCACGGAGAAGCCGGGCATCGAGATTGGTAAAGTGCCACCTCCCATCCCGGGTGTAGGCAAGC
AGCTGCCTCCAAGCTATGGGACATACCCAAGTCCTACACCTCTGGGTCCTGGGTCGACAAGCTCCCTGGAAAGGAGGAAGGAAGGCAGCT
TGCCCAGGCCCAGTGCAGGCCTGCCAAGTCGACAGAGGCCCACCCTGCTGCCCGCCACAGGCAGCACCCCCCAGCCAGGCTCCTCACAAC
AGATTCAGCAGAGGATTTCCGTACCGCCAAGTCCCACGTACCCGCCAGCGGGACCACCTGCATTTCCAGCTGGGGACAGCAAGCCTGAAC
TCCCACTGACAGTGGCCATTAGGCCTTTCCTGGCTGATAAAGGGTCAAGGCCACAGTCTCCCAGGAAAGGACCCCAGACAGTGAATTCAA
GTTCCATATACTCCATGTACCTCCAGCAAGCCACACCACCTAAGAATTACCAGCCGGCAGCACACAGCGCCTTAAATAAGTCAGTTAAAG
CAGTGTATGGTAAGCCCGTTTTACCTTCGGGTTCAACCTCTCCATCGCCGCTGCCGTTTCTTCACGGGTCACTGTCCACGGGCACACCAC
AGCCTCAGCCACCTTCAGAAAGTACTGAGAAAGAGCCTGAGCAGGATGGCCCCGCCGCCCCCGCAGATGGCAGCACCGTGGAGAGCCTGC
CACGGCCACTCAGCCCCACCAAGCTCACGCCCATCGTGCATTCGCCACTGCGCTACCAGAGTGATGCAGACCTGGAGGCCCTCCGCAGGA
AGCTGGCCAACGCGCCCCGGCCCCTGAAAAAGCGCAGCTCCATCACAGAGCCCGAGGGCCCCGGCGGGCCCAACATCCAGAAGCTGCTGT
ACCAGCGCTTCAACACCCTGGCCGGTGGCATGGAGGGCACCCCTTTCTACCAGCCCAGCCCCTCCCAGGACTTCATGGGCACCTTGGCCG
ATGTGGACAATGGAAACACCAATGCCAATGGAAACCTGGAAGAGCTCCCCCCTGCCCAGCCCACAGCCCCACTCCCCGCTGAGCCTGCCC
CGTCATCAGATGCCAATGATAATGAGTTACCTTCCCCCGAACCAGAGGAGCTCATCTGTCCCCAAACCACCCACCAAACTGCCGAGCCGG
CAGAGGACAATAACAACAACGTGGCCACGGTCCCCACCACGGAGCAGATCCCGAGTCCTGTGGCTGAGGCCCCATCTCCAGGGGAAGAGC
AGGTCCCTCCAGCACCTCTTCCCCCTGCCAGCCACCCTCCTGCCACCTCCACGAACAAGCGGACCAACTTGAAGAAGCCCAACTCGGAGC
GGACGGGGCACGGGCTGAGAGTCCGGTTTAACCCCCTGGCACTGCTCCTAGACGCGTCTCTGGAAGGAGAGTTCGATCTGGTGCAGAGGA
TCATCTATGAGGTGGAAGATCCCAGCAAGCCCAACGACGAAGGGATCACCCCACTGCACAACGCCGTCTGCGCCGGCCACCATCACATCG
TGAAGTTCCTGCTGGATTTTGGTGTCAACGTGAATGCTGCTGATAGTGATGGATGGACGCCGCTGCACTGCGCTGCCTCTTGTAACAGCG
TTCACCTCTGCAAACAGCTGGTGGAGAGTGGTGCCGCCATTTTTGCCTCAACCATAAGCGACATTGAAACTGCTGCAGACAAGTGTGAGG
AGATGGAGGAAGGCTACATCCAGTGCTCCCAGTTTCTATATGGGGTGCAGGAAAAGCTGGGTGTGATGAACAAAGGTGTGGCGTATGCTC
TGTGGGACTACGAGGCCCAGAACAGTGACGAGCTGTCCTTCCACGAAGGGGACGCCCTCACCATCCTGAGGCGCAAGGACGAAAGCGAGA
CTGAGTGGTGGTGGGCTCGCCTTGGAGACCGGGAGGGCTATGTGCCCAAAAACCTGCTGGGGCTGTATCCACGGATCAAACCCCGACAGC
GAACACTCGCCTGAACTTCCTTTTGGAGCACCGCATGGTCTTGCCAGCTACCAGGAGCCACTTAAGAGATTATTGTGCTGTTTTCCAGGA
AAGCTGCAGCTAGAAAATGGTCTTAATGGTGCTCACTTTAGCAGACAGCGTCCACAATGTGAATCCTACAGTTTCCAGGTGAGGCCCTTT
CTCCAGTTTGCCCATTAACTGGGAGAGGTACTTTCGCCTCCAAGGACTGAATTTTGCCAATTACTATAAATCCAAATAAATACCCACTTT
CAAAACACCCACCCCTCTTGCCATTAAGAAGTCCCATAACCCCCGGTTGGTTGCCAGTGAAGACAGAAGCTCTTACTGACTTGGCCCCGA
GGCCATCACCCCCTCCAGCAGTGAACACTGTCCGCCGCTGTGAGGCCTGCTCCCCTGCGACCGCCCTGCCCCCCGTCACCGAATCGGACA
CTCATCCTTTCTCACACTTCCCACACATGATCCTTCTTCCCTTCATCACCAAAGGAGCCTCTGTATGGAAACATGTCCAGTGTTGCTGCC
CAGTGTGTATGCCTCCCAGTACCCACTCTGCTCGGCCGCCTTGGGGGTTCCGCTTCCTGTTCCAGTTCACCTAAAGGCTGATTGTGCAGG
CCCAGCACTGTGGCTGGACTGCCGCGCCACGGGCACCAGGACCCCTAAGACCAAGTGACAACTGGGAGAGCCTCAGCATATACTCTTCTC
CTCCGATCTCACAGCCTGTCATGCTGCTCAGTGTGGTTCTCACCCCTGCAAGCTCAAATTCAGTTCCCTGAATGGAGTCAGGTGCTGGAG
GCCGTGGCAGCGGAGGGTGGTTGGGGTTGGGGCTGGGGGTGGACTGGTGTGAGGGCAGACCAGGGCCAGGTAGACGGGGCTGTTTGGTGC
CTGAAGGATGGCAGACGCCTGGTGTCAGGAGGGGCCGCCACCAAGGAGCAGCAGCTGGGGCAGAGGAGCTGGGGTCAGGGGCCACCCCTC
TCTGCCGATCTCCCTGCCTGGGCTGGCTGTGAGGCCACCTTTGTCCCAGGCCCAGCCTCAAGGCAAGGAGGGCGCTTCACTGAGGTGTGA
ATTGTACGTACAGGCTTTTTATATACCAAAAGTATTTTTTGACTAGACCATTCAAAGCTACCCGAACTATGTTGGAAATTTTTTTTTTCT
CATTAAAATACAGGCCCTTAGGCTCTATTTTTCATGTATGAGTCGTGTGTAATTTATGTAAAAATGTGTGTACAGACTCACTGATGCAGC
ACTGTAGCCCATCACCTTGGAGCACTGACTGTACATAGTGTGGTGAAGAAAAGTGAACGCCCTTGTAGAGCAGCCCGACCACAGGAGCAT

>1515_1515_2_ACSL5-PPP1R13B_ACSL5_chr10_114186117_ENST00000354655_PPP1R13B_chr14_104212890_ENST00000202556_length(amino acids)=1389AA_BP=622
MNFLLLFTKMLFIFNFLFSPLPTPALICILTFGAAIFLWLITRPQPVLPLLDLNNQSVGIEGGARKGVSQKNNDLTSCCFSDAKTMYEVF
QRGLAVSDNGPCLGYRKPNQPYRWLSYKQVSDRAEYLGSCLLHKGYKSSPDQFVGIFAQNRPEWIISELACYTYSMVAVPLYDTLGPEAI
VHIVNKADIAMVICDTPQKALVLIGNVEKGFTPSLKVIILMDPFDDDLKQRGEKSGIEILSLYDAENLGKEHFRKPVPPSPEDLSVICFT
SGTTGDPKGAMITHQNIVSNAAAFLKCVEHAYEPTPDDVAISYLPLAHMFERIVQAVVYSCGARVGFFQGDIRLLADDMKTLKPTLFPAV
PRLLNRIYDKVQNEAKTPLKKFLLKLAVSSKFKELQKGIIRHDSFWDKLIFAKIQDSLGGRVRVIVTGAAPMSTSVMTFFRAAMGCQVYE
AYGQTECTGGCTFTLPGDWTSGHVGVPLACNYVKLEDVADMNYFTVNNEGEVCIKGTNVFKGYLKDPEKTQEALDSDGWLHTGDIGRWLP
NGTLKIIDRKKNIFKLAQGEYIAPEKIENIYNRSQPVLQIFVHGESLRSSLVGVVVPDTDVLPSFAAKLGVKGSFEELCQNQLNRVNGTS
SPQSPLSTSGRVAAVGPYIQVPSAGSFPVLGDPIKPQSLSIASNAAHGRSKSANDGNWPTLKQNSSSSVKPVQVAGADWKDPSVEGSVKQ
GTVSSQPVPFSALGPTEKPGIEIGKVPPPIPGVGKQLPPSYGTYPSPTPLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTLLPATGSTPQ
PGSSQQIQQRISVPPSPTYPPAGPPAFPAGDSKPELPLTVAIRPFLADKGSRPQSPRKGPQTVNSSSIYSMYLQQATPPKNYQPAAHSAL
NKSVKAVYGKPVLPSGSTSPSPLPFLHGSLSTGTPQPQPPSESTEKEPEQDGPAAPADGSTVESLPRPLSPTKLTPIVHSPLRYQSDADL
EALRRKLANAPRPLKKRSSITEPEGPGGPNIQKLLYQRFNTLAGGMEGTPFYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAPL
PAEPAPSSDANDNELPSPEPEELICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEAPSPGEEQVPPAPLPPASHPPATSTNKRTNLK
KPNSERTGHGLRVRFNPLALLLDASLEGEFDLVQRIIYEVEDPSKPNDEGITPLHNAVCAGHHHIVKFLLDFGVNVNAADSDGWTPLHCA
ASCNSVHLCKQLVESGAAIFASTISDIETAADKCEEMEEGYIQCSQFLYGVQEKLGVMNKGVAYALWDYEAQNSDELSFHEGDALTILRR

--------------------------------------------------------------
>1515_1515_3_ACSL5-PPP1R13B_ACSL5_chr10_114186117_ENST00000356116_PPP1R13B_chr14_104212890_ENST00000202556_length(transcript)=5825nt_BP=2119nt
TAAAACCAGGAAGTGAAGTCCCCGAGCACGTTAGAAAGCCTGACATGGCCTGACTCGGGACAGCTCAGAGCAGGGCAGAACTGGGGACAC
TCTGGGCCGGCCTTCTGCCTGCATGGACGCTCTGAAGCCACCCTGTCTCTGGAGGAACCACGAGCGAGGGAAGAAGGACAGGGACTCGTG
TGGCAGGAAGAACTCAGAGCCGGGAAGCCCCCATTCACTAGAAGCACTGAGAGATGCGGCCCCCTCGCAGGGTCTGAATTTCCTGCTGCT
GTTCACAAAGATGCTTTTTATCTTTAACTTTTTGTTTTCCCCACTTCCGACCCCGGCGTTGATCTGCATCCTGACATTTGGAGCTGCCAT
CTTCTTGTGGCTGATCACCAGACCTCAACCCGTCTTACCTCTTCTTGACCTGAACAATCAGTCTGTGGGAATTGAGGGAGGAGCACGGAA
GGGGGTTTCCCAGAAGAACAATGACCTAACAAGTTGCTGCTTCTCAGATGCCAAGACTATGTATGAGGTTTTCCAAAGAGGACTCGCTGT
GTCTGACAATGGGCCCTGCTTGGGATATAGAAAACCAAACCAGCCCTACAGATGGCTATCTTACAAACAGGTGTCTGATAGAGCAGAGTA
CCTGGGTTCCTGTCTCTTGCATAAAGGTTATAAATCATCACCAGACCAGTTTGTCGGCATCTTTGCTCAGAATAGGCCAGAGTGGATCAT
CTCCGAATTGGCTTGTTACACGTACTCTATGGTAGCTGTACCTCTGTATGACACCTTGGGACCAGAAGCCATCGTACATATTGTCAACAA
GGCTGATATCGCCATGGTGATCTGTGACACACCCCAAAAGGCATTGGTGCTGATAGGGAATGTAGAGAAAGGCTTCACCCCGAGCCTGAA
GGTGATCATCCTTATGGACCCCTTTGATGATGACCTGAAGCAAAGAGGGGAGAAGAGTGGAATTGAGATCTTATCCCTATATGATGCTGA
GAACCTAGGCAAAGAGCACTTCAGAAAACCTGTGCCTCCTAGCCCAGAAGACCTGAGCGTCATCTGCTTCACCAGTGGGACCACAGGTGA
CCCCAAAGGAGCCATGATAACCCATCAAAATATTGTTTCAAATGCTGCTGCCTTTCTCAAATGTGTGGAGCATGCTTATGAGCCCACTCC
TGATGATGTGGCCATATCCTACCTCCCTCTGGCTCATATGTTTGAGAGGATTGTACAGGCTGTTGTGTACAGCTGTGGAGCCAGAGTTGG
ATTCTTCCAAGGGGATATTCGGTTGCTGGCTGACGACATGAAGACTTTGAAGCCCACATTGTTTCCCGCGGTGCCTCGACTCCTTAACAG
GATCTACGATAAGGTACAAAATGAGGCCAAGACACCCTTGAAGAAGTTCTTGTTGAAGCTGGCTGTTTCCAGTAAATTCAAAGAGCTTCA
AAAGGGTATCATCAGGCATGATAGTTTCTGGGACAAGCTCATCTTTGCAAAGATCCAGGACAGCCTGGGCGGAAGGGTTCGTGTAATTGT
CACTGGAGCTGCCCCCATGTCCACTTCAGTCATGACATTCTTCCGGGCAGCAATGGGATGTCAGGTGTATGAAGCTTATGGTCAAACAGA
ATGCACAGGTGGCTGTACATTTACATTACCTGGGGACTGGACATCAGGTCACGTTGGGGTGCCCCTGGCTTGCAATTACGTGAAGCTGGA
AGATGTGGCTGACATGAACTACTTTACAGTGAATAATGAAGGAGAGGTCTGCATCAAGGGTACAAACGTGTTCAAAGGATACCTGAAGGA
CCCTGAGAAGACACAGGAAGCCCTGGACAGTGATGGCTGGCTTCACACAGGAGACATTGGTCGCTGGCTCCCGAATGGAACTCTGAAGAT
CATCGACCGTAAAAAGAACATTTTCAAGCTGGCCCAAGGAGAATACATTGCACCAGAGAAGATAGAAAATATCTACAACAGGAGTCAACC
AGTGTTACAAATTTTTGTACACGGGGAGAGCTTACGGTCATCCTTAGTAGGAGTGGTGGTTCCTGACACAGATGTACTTCCCTCATTTGC
AGCCAAGCTTGGGGTGAAGGGCTCCTTTGAGGAACTGTGCCAAAACCAACTGAACCGTGTGAATGGCACGTCATCACCACAGTCCCCTCT
GAGCACATCGGGCAGGGTCGCTGCTGTGGGGCCTTATATCCAGGTTCCCAGTGCCGGAAGCTTTCCTGTGCTGGGGGACCCTATAAAGCC
CCAGTCTCTCAGTATTGCCTCAAATGCTGCTCATGGAAGATCCAAATCCGCTAATGATGGAAACTGGCCAACATTAAAACAGAATTCTAG
CTCTTCCGTGAAACCAGTGCAGGTGGCCGGTGCAGACTGGAAGGATCCGAGCGTGGAGGGGTCTGTCAAGCAGGGCACTGTCTCCAGCCA
GCCTGTGCCCTTCTCAGCACTGGGACCCACGGAGAAGCCGGGCATCGAGATTGGTAAAGTGCCACCTCCCATCCCGGGTGTAGGCAAGCA
GCTGCCTCCAAGCTATGGGACATACCCAAGTCCTACACCTCTGGGTCCTGGGTCGACAAGCTCCCTGGAAAGGAGGAAGGAAGGCAGCTT
GCCCAGGCCCAGTGCAGGCCTGCCAAGTCGACAGAGGCCCACCCTGCTGCCCGCCACAGGCAGCACCCCCCAGCCAGGCTCCTCACAACA
GATTCAGCAGAGGATTTCCGTACCGCCAAGTCCCACGTACCCGCCAGCGGGACCACCTGCATTTCCAGCTGGGGACAGCAAGCCTGAACT
CCCACTGACAGTGGCCATTAGGCCTTTCCTGGCTGATAAAGGGTCAAGGCCACAGTCTCCCAGGAAAGGACCCCAGACAGTGAATTCAAG
TTCCATATACTCCATGTACCTCCAGCAAGCCACACCACCTAAGAATTACCAGCCGGCAGCACACAGCGCCTTAAATAAGTCAGTTAAAGC
AGTGTATGGTAAGCCCGTTTTACCTTCGGGTTCAACCTCTCCATCGCCGCTGCCGTTTCTTCACGGGTCACTGTCCACGGGCACACCACA
GCCTCAGCCACCTTCAGAAAGTACTGAGAAAGAGCCTGAGCAGGATGGCCCCGCCGCCCCCGCAGATGGCAGCACCGTGGAGAGCCTGCC
ACGGCCACTCAGCCCCACCAAGCTCACGCCCATCGTGCATTCGCCACTGCGCTACCAGAGTGATGCAGACCTGGAGGCCCTCCGCAGGAA
GCTGGCCAACGCGCCCCGGCCCCTGAAAAAGCGCAGCTCCATCACAGAGCCCGAGGGCCCCGGCGGGCCCAACATCCAGAAGCTGCTGTA
CCAGCGCTTCAACACCCTGGCCGGTGGCATGGAGGGCACCCCTTTCTACCAGCCCAGCCCCTCCCAGGACTTCATGGGCACCTTGGCCGA
TGTGGACAATGGAAACACCAATGCCAATGGAAACCTGGAAGAGCTCCCCCCTGCCCAGCCCACAGCCCCACTCCCCGCTGAGCCTGCCCC
GTCATCAGATGCCAATGATAATGAGTTACCTTCCCCCGAACCAGAGGAGCTCATCTGTCCCCAAACCACCCACCAAACTGCCGAGCCGGC
AGAGGACAATAACAACAACGTGGCCACGGTCCCCACCACGGAGCAGATCCCGAGTCCTGTGGCTGAGGCCCCATCTCCAGGGGAAGAGCA
GGTCCCTCCAGCACCTCTTCCCCCTGCCAGCCACCCTCCTGCCACCTCCACGAACAAGCGGACCAACTTGAAGAAGCCCAACTCGGAGCG
GACGGGGCACGGGCTGAGAGTCCGGTTTAACCCCCTGGCACTGCTCCTAGACGCGTCTCTGGAAGGAGAGTTCGATCTGGTGCAGAGGAT
CATCTATGAGGTGGAAGATCCCAGCAAGCCCAACGACGAAGGGATCACCCCACTGCACAACGCCGTCTGCGCCGGCCACCATCACATCGT
GAAGTTCCTGCTGGATTTTGGTGTCAACGTGAATGCTGCTGATAGTGATGGATGGACGCCGCTGCACTGCGCTGCCTCTTGTAACAGCGT
TCACCTCTGCAAACAGCTGGTGGAGAGTGGTGCCGCCATTTTTGCCTCAACCATAAGCGACATTGAAACTGCTGCAGACAAGTGTGAGGA
GATGGAGGAAGGCTACATCCAGTGCTCCCAGTTTCTATATGGGGTGCAGGAAAAGCTGGGTGTGATGAACAAAGGTGTGGCGTATGCTCT
GTGGGACTACGAGGCCCAGAACAGTGACGAGCTGTCCTTCCACGAAGGGGACGCCCTCACCATCCTGAGGCGCAAGGACGAAAGCGAGAC
TGAGTGGTGGTGGGCTCGCCTTGGAGACCGGGAGGGCTATGTGCCCAAAAACCTGCTGGGGCTGTATCCACGGATCAAACCCCGACAGCG
AACACTCGCCTGAACTTCCTTTTGGAGCACCGCATGGTCTTGCCAGCTACCAGGAGCCACTTAAGAGATTATTGTGCTGTTTTCCAGGAA
AGCTGCAGCTAGAAAATGGTCTTAATGGTGCTCACTTTAGCAGACAGCGTCCACAATGTGAATCCTACAGTTTCCAGGTGAGGCCCTTTC
TCCAGTTTGCCCATTAACTGGGAGAGGTACTTTCGCCTCCAAGGACTGAATTTTGCCAATTACTATAAATCCAAATAAATACCCACTTTC
AAAACACCCACCCCTCTTGCCATTAAGAAGTCCCATAACCCCCGGTTGGTTGCCAGTGAAGACAGAAGCTCTTACTGACTTGGCCCCGAG
GCCATCACCCCCTCCAGCAGTGAACACTGTCCGCCGCTGTGAGGCCTGCTCCCCTGCGACCGCCCTGCCCCCCGTCACCGAATCGGACAC
TCATCCTTTCTCACACTTCCCACACATGATCCTTCTTCCCTTCATCACCAAAGGAGCCTCTGTATGGAAACATGTCCAGTGTTGCTGCCC
AGTGTGTATGCCTCCCAGTACCCACTCTGCTCGGCCGCCTTGGGGGTTCCGCTTCCTGTTCCAGTTCACCTAAAGGCTGATTGTGCAGGC
CCAGCACTGTGGCTGGACTGCCGCGCCACGGGCACCAGGACCCCTAAGACCAAGTGACAACTGGGAGAGCCTCAGCATATACTCTTCTCC
TCCGATCTCACAGCCTGTCATGCTGCTCAGTGTGGTTCTCACCCCTGCAAGCTCAAATTCAGTTCCCTGAATGGAGTCAGGTGCTGGAGG
CCGTGGCAGCGGAGGGTGGTTGGGGTTGGGGCTGGGGGTGGACTGGTGTGAGGGCAGACCAGGGCCAGGTAGACGGGGCTGTTTGGTGCC
TGAAGGATGGCAGACGCCTGGTGTCAGGAGGGGCCGCCACCAAGGAGCAGCAGCTGGGGCAGAGGAGCTGGGGTCAGGGGCCACCCCTCT
CTGCCGATCTCCCTGCCTGGGCTGGCTGTGAGGCCACCTTTGTCCCAGGCCCAGCCTCAAGGCAAGGAGGGCGCTTCACTGAGGTGTGAA
TTGTACGTACAGGCTTTTTATATACCAAAAGTATTTTTTGACTAGACCATTCAAAGCTACCCGAACTATGTTGGAAATTTTTTTTTTCTC
ATTAAAATACAGGCCCTTAGGCTCTATTTTTCATGTATGAGTCGTGTGTAATTTATGTAAAAATGTGTGTACAGACTCACTGATGCAGCA
CTGTAGCCCATCACCTTGGAGCACTGACTGTACATAGTGTGGTGAAGAAAAGTGAACGCCCTTGTAGAGCAGCCCGACCACAGGAGCATG

>1515_1515_3_ACSL5-PPP1R13B_ACSL5_chr10_114186117_ENST00000356116_PPP1R13B_chr14_104212890_ENST00000202556_length(amino acids)=1457AA_BP=690
MTRDSSEQGRTGDTLGRPSACMDALKPPCLWRNHERGKKDRDSCGRKNSEPGSPHSLEALRDAAPSQGLNFLLLFTKMLFIFNFLFSPLP
TPALICILTFGAAIFLWLITRPQPVLPLLDLNNQSVGIEGGARKGVSQKNNDLTSCCFSDAKTMYEVFQRGLAVSDNGPCLGYRKPNQPY
RWLSYKQVSDRAEYLGSCLLHKGYKSSPDQFVGIFAQNRPEWIISELACYTYSMVAVPLYDTLGPEAIVHIVNKADIAMVICDTPQKALV
LIGNVEKGFTPSLKVIILMDPFDDDLKQRGEKSGIEILSLYDAENLGKEHFRKPVPPSPEDLSVICFTSGTTGDPKGAMITHQNIVSNAA
AFLKCVEHAYEPTPDDVAISYLPLAHMFERIVQAVVYSCGARVGFFQGDIRLLADDMKTLKPTLFPAVPRLLNRIYDKVQNEAKTPLKKF
LLKLAVSSKFKELQKGIIRHDSFWDKLIFAKIQDSLGGRVRVIVTGAAPMSTSVMTFFRAAMGCQVYEAYGQTECTGGCTFTLPGDWTSG
HVGVPLACNYVKLEDVADMNYFTVNNEGEVCIKGTNVFKGYLKDPEKTQEALDSDGWLHTGDIGRWLPNGTLKIIDRKKNIFKLAQGEYI
APEKIENIYNRSQPVLQIFVHGESLRSSLVGVVVPDTDVLPSFAAKLGVKGSFEELCQNQLNRVNGTSSPQSPLSTSGRVAAVGPYIQVP
SAGSFPVLGDPIKPQSLSIASNAAHGRSKSANDGNWPTLKQNSSSSVKPVQVAGADWKDPSVEGSVKQGTVSSQPVPFSALGPTEKPGIE
IGKVPPPIPGVGKQLPPSYGTYPSPTPLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTLLPATGSTPQPGSSQQIQQRISVPPSPTYPPA
GPPAFPAGDSKPELPLTVAIRPFLADKGSRPQSPRKGPQTVNSSSIYSMYLQQATPPKNYQPAAHSALNKSVKAVYGKPVLPSGSTSPSP
LPFLHGSLSTGTPQPQPPSESTEKEPEQDGPAAPADGSTVESLPRPLSPTKLTPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSSITE
PEGPGGPNIQKLLYQRFNTLAGGMEGTPFYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAPLPAEPAPSSDANDNELPSPEPEE
LICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEAPSPGEEQVPPAPLPPASHPPATSTNKRTNLKKPNSERTGHGLRVRFNPLALLL
DASLEGEFDLVQRIIYEVEDPSKPNDEGITPLHNAVCAGHHHIVKFLLDFGVNVNAADSDGWTPLHCAASCNSVHLCKQLVESGAAIFAS
TISDIETAADKCEEMEEGYIQCSQFLYGVQEKLGVMNKGVAYALWDYEAQNSDELSFHEGDALTILRRKDESETEWWWARLGDREGYVPK

--------------------------------------------------------------
>1515_1515_4_ACSL5-PPP1R13B_ACSL5_chr10_114186117_ENST00000369410_PPP1R13B_chr14_104212890_ENST00000202556_length(transcript)=5055nt_BP=1349nt
ATTGGTGCTGATAGGGAATGTAGAGAAAGGCTTCACCCCGAGCCTGAAGGTGATCATCCTTATGGACCCCTTTGATGATGACCTGAAGCA
AAGAGGGGAGAAGAGTGGAATTGAGATCTTATCCCTATATGATGCTGAGGTAGATGATTTTCTAGAGAAATCTTATGCTCTTCCCTGGGG
CTTCCATTGTTCCTGAATGTTGGCTTCTGGTCCTGATCCAGAACCTAGGCAAAGAGCACTTCAGAAAACCTGTGCCTCCTAGCCCAGAAG
ACCTGAGCGTCATCTGCTTCACCAGTGGGACCACAGGTGACCCCAAAGGAGCCATGATAACCCATCAAAATATTGTTTCAAATGCTGCTG
CCTTTCTCAAATGTGTGGAGCATGCTTATGAGCCCACTCCTGATGATGTGGCCATATCCTACCTCCCTCTGGCTCATATGTTTGAGAGGA
TTGTACAGGCTGTTGTGTACAGCTGTGGAGCCAGAGTTGGATTCTTCCAAGGGGATATTCGGTTGCTGGCTGACGACATGAAGACTTTGA
AGCCCACATTGTTTCCCGCGGTGCCTCGACTCCTTAACAGGATCTACGATAAGGTACAAAATGAGGCCAAGACACCCTTGAAGAAGTTCT
TGTTGAAGCTGGCTGTTTCCAGTAAATTCAAAGAGCTTCAAAAGGGTATCATCAGGCATGATAGTTTCTGGGACAAGCTCATCTTTGCAA
AGATCCAGGACAGCCTGGGCGGAAGGGTTCGTGTAATTGTCACTGGAGCTGCCCCCATGTCCACTTCAGTCATGACATTCTTCCGGGCAG
CAATGGGATGTCAGGTGTATGAAGCTTATGGTCAAACAGAATGCACAGGTGGCTGTACATTTACATTACCTGGGGACTGGACATCAGGTC
ACGTTGGGGTGCCCCTGGCTTGCAATTACGTGAAGCTGGAAGATGTGGCTGACATGAACTACTTTACAGTGAATAATGAAGGAGAGGTCT
GCATCAAGGGTACAAACGTGTTCAAAGGATACCTGAAGGACCCTGAGAAGACACAGGAAGCCCTGGACAGTGATGGCTGGCTTCACACAG
GAGACATTGGTCGCTGGCTCCCGAATGGAACTCTGAAGATCATCGACCGTAAAAAGAACATTTTCAAGCTGGCCCAAGGAGAATACATTG
CACCAGAGAAGATAGAAAATATCTACAACAGGAGTCAACCAGTGTTACAAATTTTTGTACACGGGGAGAGCTTACGGTCATCCTTAGTAG
GAGTGGTGGTTCCTGACACAGATGTACTTCCCTCATTTGCAGCCAAGCTTGGGGTGAAGGGCTCCTTTGAGGAACTGTGCCAAAACCAAC
TGAACCGTGTGAATGGCACGTCATCACCACAGTCCCCTCTGAGCACATCGGGCAGGGTCGCTGCTGTGGGGCCTTATATCCAGGTTCCCA
GTGCCGGAAGCTTTCCTGTGCTGGGGGACCCTATAAAGCCCCAGTCTCTCAGTATTGCCTCAAATGCTGCTCATGGAAGATCCAAATCCG
CTAATGATGGAAACTGGCCAACATTAAAACAGAATTCTAGCTCTTCCGTGAAACCAGTGCAGGTGGCCGGTGCAGACTGGAAGGATCCGA
GCGTGGAGGGGTCTGTCAAGCAGGGCACTGTCTCCAGCCAGCCTGTGCCCTTCTCAGCACTGGGACCCACGGAGAAGCCGGGCATCGAGA
TTGGTAAAGTGCCACCTCCCATCCCGGGTGTAGGCAAGCAGCTGCCTCCAAGCTATGGGACATACCCAAGTCCTACACCTCTGGGTCCTG
GGTCGACAAGCTCCCTGGAAAGGAGGAAGGAAGGCAGCTTGCCCAGGCCCAGTGCAGGCCTGCCAAGTCGACAGAGGCCCACCCTGCTGC
CCGCCACAGGCAGCACCCCCCAGCCAGGCTCCTCACAACAGATTCAGCAGAGGATTTCCGTACCGCCAAGTCCCACGTACCCGCCAGCGG
GACCACCTGCATTTCCAGCTGGGGACAGCAAGCCTGAACTCCCACTGACAGTGGCCATTAGGCCTTTCCTGGCTGATAAAGGGTCAAGGC
CACAGTCTCCCAGGAAAGGACCCCAGACAGTGAATTCAAGTTCCATATACTCCATGTACCTCCAGCAAGCCACACCACCTAAGAATTACC
AGCCGGCAGCACACAGCGCCTTAAATAAGTCAGTTAAAGCAGTGTATGGTAAGCCCGTTTTACCTTCGGGTTCAACCTCTCCATCGCCGC
TGCCGTTTCTTCACGGGTCACTGTCCACGGGCACACCACAGCCTCAGCCACCTTCAGAAAGTACTGAGAAAGAGCCTGAGCAGGATGGCC
CCGCCGCCCCCGCAGATGGCAGCACCGTGGAGAGCCTGCCACGGCCACTCAGCCCCACCAAGCTCACGCCCATCGTGCATTCGCCACTGC
GCTACCAGAGTGATGCAGACCTGGAGGCCCTCCGCAGGAAGCTGGCCAACGCGCCCCGGCCCCTGAAAAAGCGCAGCTCCATCACAGAGC
CCGAGGGCCCCGGCGGGCCCAACATCCAGAAGCTGCTGTACCAGCGCTTCAACACCCTGGCCGGTGGCATGGAGGGCACCCCTTTCTACC
AGCCCAGCCCCTCCCAGGACTTCATGGGCACCTTGGCCGATGTGGACAATGGAAACACCAATGCCAATGGAAACCTGGAAGAGCTCCCCC
CTGCCCAGCCCACAGCCCCACTCCCCGCTGAGCCTGCCCCGTCATCAGATGCCAATGATAATGAGTTACCTTCCCCCGAACCAGAGGAGC
TCATCTGTCCCCAAACCACCCACCAAACTGCCGAGCCGGCAGAGGACAATAACAACAACGTGGCCACGGTCCCCACCACGGAGCAGATCC
CGAGTCCTGTGGCTGAGGCCCCATCTCCAGGGGAAGAGCAGGTCCCTCCAGCACCTCTTCCCCCTGCCAGCCACCCTCCTGCCACCTCCA
CGAACAAGCGGACCAACTTGAAGAAGCCCAACTCGGAGCGGACGGGGCACGGGCTGAGAGTCCGGTTTAACCCCCTGGCACTGCTCCTAG
ACGCGTCTCTGGAAGGAGAGTTCGATCTGGTGCAGAGGATCATCTATGAGGTGGAAGATCCCAGCAAGCCCAACGACGAAGGGATCACCC
CACTGCACAACGCCGTCTGCGCCGGCCACCATCACATCGTGAAGTTCCTGCTGGATTTTGGTGTCAACGTGAATGCTGCTGATAGTGATG
GATGGACGCCGCTGCACTGCGCTGCCTCTTGTAACAGCGTTCACCTCTGCAAACAGCTGGTGGAGAGTGGTGCCGCCATTTTTGCCTCAA
CCATAAGCGACATTGAAACTGCTGCAGACAAGTGTGAGGAGATGGAGGAAGGCTACATCCAGTGCTCCCAGTTTCTATATGGGGTGCAGG
AAAAGCTGGGTGTGATGAACAAAGGTGTGGCGTATGCTCTGTGGGACTACGAGGCCCAGAACAGTGACGAGCTGTCCTTCCACGAAGGGG
ACGCCCTCACCATCCTGAGGCGCAAGGACGAAAGCGAGACTGAGTGGTGGTGGGCTCGCCTTGGAGACCGGGAGGGCTATGTGCCCAAAA
ACCTGCTGGGGCTGTATCCACGGATCAAACCCCGACAGCGAACACTCGCCTGAACTTCCTTTTGGAGCACCGCATGGTCTTGCCAGCTAC
CAGGAGCCACTTAAGAGATTATTGTGCTGTTTTCCAGGAAAGCTGCAGCTAGAAAATGGTCTTAATGGTGCTCACTTTAGCAGACAGCGT
CCACAATGTGAATCCTACAGTTTCCAGGTGAGGCCCTTTCTCCAGTTTGCCCATTAACTGGGAGAGGTACTTTCGCCTCCAAGGACTGAA
TTTTGCCAATTACTATAAATCCAAATAAATACCCACTTTCAAAACACCCACCCCTCTTGCCATTAAGAAGTCCCATAACCCCCGGTTGGT
TGCCAGTGAAGACAGAAGCTCTTACTGACTTGGCCCCGAGGCCATCACCCCCTCCAGCAGTGAACACTGTCCGCCGCTGTGAGGCCTGCT
CCCCTGCGACCGCCCTGCCCCCCGTCACCGAATCGGACACTCATCCTTTCTCACACTTCCCACACATGATCCTTCTTCCCTTCATCACCA
AAGGAGCCTCTGTATGGAAACATGTCCAGTGTTGCTGCCCAGTGTGTATGCCTCCCAGTACCCACTCTGCTCGGCCGCCTTGGGGGTTCC
GCTTCCTGTTCCAGTTCACCTAAAGGCTGATTGTGCAGGCCCAGCACTGTGGCTGGACTGCCGCGCCACGGGCACCAGGACCCCTAAGAC
CAAGTGACAACTGGGAGAGCCTCAGCATATACTCTTCTCCTCCGATCTCACAGCCTGTCATGCTGCTCAGTGTGGTTCTCACCCCTGCAA
GCTCAAATTCAGTTCCCTGAATGGAGTCAGGTGCTGGAGGCCGTGGCAGCGGAGGGTGGTTGGGGTTGGGGCTGGGGGTGGACTGGTGTG
AGGGCAGACCAGGGCCAGGTAGACGGGGCTGTTTGGTGCCTGAAGGATGGCAGACGCCTGGTGTCAGGAGGGGCCGCCACCAAGGAGCAG
CAGCTGGGGCAGAGGAGCTGGGGTCAGGGGCCACCCCTCTCTGCCGATCTCCCTGCCTGGGCTGGCTGTGAGGCCACCTTTGTCCCAGGC
CCAGCCTCAAGGCAAGGAGGGCGCTTCACTGAGGTGTGAATTGTACGTACAGGCTTTTTATATACCAAAAGTATTTTTTGACTAGACCAT
TCAAAGCTACCCGAACTATGTTGGAAATTTTTTTTTTCTCATTAAAATACAGGCCCTTAGGCTCTATTTTTCATGTATGAGTCGTGTGTA
ATTTATGTAAAAATGTGTGTACAGACTCACTGATGCAGCACTGTAGCCCATCACCTTGGAGCACTGACTGTACATAGTGTGGTGAAGAAA
AGTGAACGCCCTTGTAGAGCAGCCCGACCACAGGAGCATGGCCGCTGCCAGCCCAGACGCTGCTGACGCTGTGTAAATGTGCACAATAAA

>1515_1515_4_ACSL5-PPP1R13B_ACSL5_chr10_114186117_ENST00000369410_PPP1R13B_chr14_104212890_ENST00000202556_length(amino acids)=1162AA_BP=395
MLFPGASIVPECWLLVLIQNLGKEHFRKPVPPSPEDLSVICFTSGTTGDPKGAMITHQNIVSNAAAFLKCVEHAYEPTPDDVAISYLPLA
HMFERIVQAVVYSCGARVGFFQGDIRLLADDMKTLKPTLFPAVPRLLNRIYDKVQNEAKTPLKKFLLKLAVSSKFKELQKGIIRHDSFWD
KLIFAKIQDSLGGRVRVIVTGAAPMSTSVMTFFRAAMGCQVYEAYGQTECTGGCTFTLPGDWTSGHVGVPLACNYVKLEDVADMNYFTVN
NEGEVCIKGTNVFKGYLKDPEKTQEALDSDGWLHTGDIGRWLPNGTLKIIDRKKNIFKLAQGEYIAPEKIENIYNRSQPVLQIFVHGESL
RSSLVGVVVPDTDVLPSFAAKLGVKGSFEELCQNQLNRVNGTSSPQSPLSTSGRVAAVGPYIQVPSAGSFPVLGDPIKPQSLSIASNAAH
GRSKSANDGNWPTLKQNSSSSVKPVQVAGADWKDPSVEGSVKQGTVSSQPVPFSALGPTEKPGIEIGKVPPPIPGVGKQLPPSYGTYPSP
TPLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTLLPATGSTPQPGSSQQIQQRISVPPSPTYPPAGPPAFPAGDSKPELPLTVAIRPFLA
DKGSRPQSPRKGPQTVNSSSIYSMYLQQATPPKNYQPAAHSALNKSVKAVYGKPVLPSGSTSPSPLPFLHGSLSTGTPQPQPPSESTEKE
PEQDGPAAPADGSTVESLPRPLSPTKLTPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSSITEPEGPGGPNIQKLLYQRFNTLAGGME
GTPFYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAPLPAEPAPSSDANDNELPSPEPEELICPQTTHQTAEPAEDNNNNVATVP
TTEQIPSPVAEAPSPGEEQVPPAPLPPASHPPATSTNKRTNLKKPNSERTGHGLRVRFNPLALLLDASLEGEFDLVQRIIYEVEDPSKPN
DEGITPLHNAVCAGHHHIVKFLLDFGVNVNAADSDGWTPLHCAASCNSVHLCKQLVESGAAIFASTISDIETAADKCEEMEEGYIQCSQF

--------------------------------------------------------------
>1515_1515_5_ACSL5-PPP1R13B_ACSL5_chr10_114186117_ENST00000393081_PPP1R13B_chr14_104212890_ENST00000202556_length(transcript)=5852nt_BP=2146nt
GCCAGAGGATGGAATGCCACAGGCCCCACTTCGTCTCCCAGCCCTTCATCTTTCTTCCATGTCCAAAGGCGGCTCCCCAGAGGCCAAGGG
CTCAGCTCTTGTGTTCTCTGAGACTGTGGCACAGCTCACCCTGGCTTCCTTAGTAGGAAGCTTTTAAGAACTGCTCTGTAGAAAGAACAA
ACCCTAATCTAGCTCCAGCAAAGAGCCAGGATCATGCTGAACTTCCTGTGAGCCTTCGTGGGGGATCGAGGCTGGAGAAAGTGCTGCTTC
ATTCTGAGGTCTGAATTTCCTGCTGCTGTTCACAAAGATGCTTTTTATCTTTAACTTTTTGTTTTCCCCACTTCCGACCCCGGCGTTGAT
CTGCATCCTGACATTTGGAGCTGCCATCTTCTTGTGGCTGATCACCAGACCTCAACCCGTCTTACCTCTTCTTGACCTGAACAATCAGTC
TGTGGGAATTGAGGGAGGAGCACGGAAGGGGGTTTCCCAGAAGAACAATGACCTAACAAGTTGCTGCTTCTCAGATGCCAAGACTATGTA
TGAGGTTTTCCAAAGAGGACTCGCTGTGTCTGACAATGGGCCCTGCTTGGGATATAGAAAACCAAACCAGCCCTACAGATGGCTATCTTA
CAAACAGGTGTCTGATAGAGCAGAGTACCTGGGTTCCTGTCTCTTGCATAAAGGTTATAAATCATCACCAGACCAGTTTGTCGGCATCTT
TGCTCAGAATAGGCCAGAGTGGATCATCTCCGAATTGGCTTGTTACACGTACTCTATGGTAGCTGTACCTCTGTATGACACCTTGGGACC
AGAAGCCATCGTACATATTGTCAACAAGGCTGATATCGCCATGGTGATCTGTGACACACCCCAAAAGGCATTGGTGCTGATAGGGAATGT
AGAGAAAGGCTTCACCCCGAGCCTGAAGGTGATCATCCTTATGGACCCCTTTGATGATGACCTGAAGCAAAGAGGGGAGAAGAGTGGAAT
TGAGATCTTATCCCTATATGATGCTGAGAACCTAGGCAAAGAGCACTTCAGAAAACCTGTGCCTCCTAGCCCAGAAGACCTGAGCGTCAT
CTGCTTCACCAGTGGGACCACAGGTGACCCCAAAGGAGCCATGATAACCCATCAAAATATTGTTTCAAATGCTGCTGCCTTTCTCAAATG
TGTGGAGCATGCTTATGAGCCCACTCCTGATGATGTGGCCATATCCTACCTCCCTCTGGCTCATATGTTTGAGAGGATTGTACAGGCTGT
TGTGTACAGCTGTGGAGCCAGAGTTGGATTCTTCCAAGGGGATATTCGGTTGCTGGCTGACGACATGAAGACTTTGAAGCCCACATTGTT
TCCCGCGGTGCCTCGACTCCTTAACAGGATCTACGATAAGGTACAAAATGAGGCCAAGACACCCTTGAAGAAGTTCTTGTTGAAGCTGGC
TGTTTCCAGTAAATTCAAAGAGCTTCAAAAGGGTATCATCAGGCATGATAGTTTCTGGGACAAGCTCATCTTTGCAAAGATCCAGGACAG
CCTGGGCGGAAGGGTTCGTGTAATTGTCACTGGAGCTGCCCCCATGTCCACTTCAGTCATGACATTCTTCCGGGCAGCAATGGGATGTCA
GGTGTATGAAGCTTATGGTCAAACAGAATGCACAGGTGGCTGTACATTTACATTACCTGGGGACTGGACATCAGGTCACGTTGGGGTGCC
CCTGGCTTGCAATTACGTGAAGCTGGAAGATGTGGCTGACATGAACTACTTTACAGTGAATAATGAAGGAGAGGTCTGCATCAAGGGTAC
AAACGTGTTCAAAGGATACCTGAAGGACCCTGAGAAGACACAGGAAGCCCTGGACAGTGATGGCTGGCTTCACACAGGAGACATTGGTCG
CTGGCTCCCGAATGGAACTCTGAAGATCATCGACCGTAAAAAGAACATTTTCAAGCTGGCCCAAGGAGAATACATTGCACCAGAGAAGAT
AGAAAATATCTACAACAGGAGTCAACCAGTGTTACAAATTTTTGTACACGGGGAGAGCTTACGGTCATCCTTAGTAGGAGTGGTGGTTCC
TGACACAGATGTACTTCCCTCATTTGCAGCCAAGCTTGGGGTGAAGGGCTCCTTTGAGGAACTGTGCCAAAACCAACTGAACCGTGTGAA
TGGCACGTCATCACCACAGTCCCCTCTGAGCACATCGGGCAGGGTCGCTGCTGTGGGGCCTTATATCCAGGTTCCCAGTGCCGGAAGCTT
TCCTGTGCTGGGGGACCCTATAAAGCCCCAGTCTCTCAGTATTGCCTCAAATGCTGCTCATGGAAGATCCAAATCCGCTAATGATGGAAA
CTGGCCAACATTAAAACAGAATTCTAGCTCTTCCGTGAAACCAGTGCAGGTGGCCGGTGCAGACTGGAAGGATCCGAGCGTGGAGGGGTC
TGTCAAGCAGGGCACTGTCTCCAGCCAGCCTGTGCCCTTCTCAGCACTGGGACCCACGGAGAAGCCGGGCATCGAGATTGGTAAAGTGCC
ACCTCCCATCCCGGGTGTAGGCAAGCAGCTGCCTCCAAGCTATGGGACATACCCAAGTCCTACACCTCTGGGTCCTGGGTCGACAAGCTC
CCTGGAAAGGAGGAAGGAAGGCAGCTTGCCCAGGCCCAGTGCAGGCCTGCCAAGTCGACAGAGGCCCACCCTGCTGCCCGCCACAGGCAG
CACCCCCCAGCCAGGCTCCTCACAACAGATTCAGCAGAGGATTTCCGTACCGCCAAGTCCCACGTACCCGCCAGCGGGACCACCTGCATT
TCCAGCTGGGGACAGCAAGCCTGAACTCCCACTGACAGTGGCCATTAGGCCTTTCCTGGCTGATAAAGGGTCAAGGCCACAGTCTCCCAG
GAAAGGACCCCAGACAGTGAATTCAAGTTCCATATACTCCATGTACCTCCAGCAAGCCACACCACCTAAGAATTACCAGCCGGCAGCACA
CAGCGCCTTAAATAAGTCAGTTAAAGCAGTGTATGGTAAGCCCGTTTTACCTTCGGGTTCAACCTCTCCATCGCCGCTGCCGTTTCTTCA
CGGGTCACTGTCCACGGGCACACCACAGCCTCAGCCACCTTCAGAAAGTACTGAGAAAGAGCCTGAGCAGGATGGCCCCGCCGCCCCCGC
AGATGGCAGCACCGTGGAGAGCCTGCCACGGCCACTCAGCCCCACCAAGCTCACGCCCATCGTGCATTCGCCACTGCGCTACCAGAGTGA
TGCAGACCTGGAGGCCCTCCGCAGGAAGCTGGCCAACGCGCCCCGGCCCCTGAAAAAGCGCAGCTCCATCACAGAGCCCGAGGGCCCCGG
CGGGCCCAACATCCAGAAGCTGCTGTACCAGCGCTTCAACACCCTGGCCGGTGGCATGGAGGGCACCCCTTTCTACCAGCCCAGCCCCTC
CCAGGACTTCATGGGCACCTTGGCCGATGTGGACAATGGAAACACCAATGCCAATGGAAACCTGGAAGAGCTCCCCCCTGCCCAGCCCAC
AGCCCCACTCCCCGCTGAGCCTGCCCCGTCATCAGATGCCAATGATAATGAGTTACCTTCCCCCGAACCAGAGGAGCTCATCTGTCCCCA
AACCACCCACCAAACTGCCGAGCCGGCAGAGGACAATAACAACAACGTGGCCACGGTCCCCACCACGGAGCAGATCCCGAGTCCTGTGGC
TGAGGCCCCATCTCCAGGGGAAGAGCAGGTCCCTCCAGCACCTCTTCCCCCTGCCAGCCACCCTCCTGCCACCTCCACGAACAAGCGGAC
CAACTTGAAGAAGCCCAACTCGGAGCGGACGGGGCACGGGCTGAGAGTCCGGTTTAACCCCCTGGCACTGCTCCTAGACGCGTCTCTGGA
AGGAGAGTTCGATCTGGTGCAGAGGATCATCTATGAGGTGGAAGATCCCAGCAAGCCCAACGACGAAGGGATCACCCCACTGCACAACGC
CGTCTGCGCCGGCCACCATCACATCGTGAAGTTCCTGCTGGATTTTGGTGTCAACGTGAATGCTGCTGATAGTGATGGATGGACGCCGCT
GCACTGCGCTGCCTCTTGTAACAGCGTTCACCTCTGCAAACAGCTGGTGGAGAGTGGTGCCGCCATTTTTGCCTCAACCATAAGCGACAT
TGAAACTGCTGCAGACAAGTGTGAGGAGATGGAGGAAGGCTACATCCAGTGCTCCCAGTTTCTATATGGGGTGCAGGAAAAGCTGGGTGT
GATGAACAAAGGTGTGGCGTATGCTCTGTGGGACTACGAGGCCCAGAACAGTGACGAGCTGTCCTTCCACGAAGGGGACGCCCTCACCAT
CCTGAGGCGCAAGGACGAAAGCGAGACTGAGTGGTGGTGGGCTCGCCTTGGAGACCGGGAGGGCTATGTGCCCAAAAACCTGCTGGGGCT
GTATCCACGGATCAAACCCCGACAGCGAACACTCGCCTGAACTTCCTTTTGGAGCACCGCATGGTCTTGCCAGCTACCAGGAGCCACTTA
AGAGATTATTGTGCTGTTTTCCAGGAAAGCTGCAGCTAGAAAATGGTCTTAATGGTGCTCACTTTAGCAGACAGCGTCCACAATGTGAAT
CCTACAGTTTCCAGGTGAGGCCCTTTCTCCAGTTTGCCCATTAACTGGGAGAGGTACTTTCGCCTCCAAGGACTGAATTTTGCCAATTAC
TATAAATCCAAATAAATACCCACTTTCAAAACACCCACCCCTCTTGCCATTAAGAAGTCCCATAACCCCCGGTTGGTTGCCAGTGAAGAC
AGAAGCTCTTACTGACTTGGCCCCGAGGCCATCACCCCCTCCAGCAGTGAACACTGTCCGCCGCTGTGAGGCCTGCTCCCCTGCGACCGC
CCTGCCCCCCGTCACCGAATCGGACACTCATCCTTTCTCACACTTCCCACACATGATCCTTCTTCCCTTCATCACCAAAGGAGCCTCTGT
ATGGAAACATGTCCAGTGTTGCTGCCCAGTGTGTATGCCTCCCAGTACCCACTCTGCTCGGCCGCCTTGGGGGTTCCGCTTCCTGTTCCA
GTTCACCTAAAGGCTGATTGTGCAGGCCCAGCACTGTGGCTGGACTGCCGCGCCACGGGCACCAGGACCCCTAAGACCAAGTGACAACTG
GGAGAGCCTCAGCATATACTCTTCTCCTCCGATCTCACAGCCTGTCATGCTGCTCAGTGTGGTTCTCACCCCTGCAAGCTCAAATTCAGT
TCCCTGAATGGAGTCAGGTGCTGGAGGCCGTGGCAGCGGAGGGTGGTTGGGGTTGGGGCTGGGGGTGGACTGGTGTGAGGGCAGACCAGG
GCCAGGTAGACGGGGCTGTTTGGTGCCTGAAGGATGGCAGACGCCTGGTGTCAGGAGGGGCCGCCACCAAGGAGCAGCAGCTGGGGCAGA
GGAGCTGGGGTCAGGGGCCACCCCTCTCTGCCGATCTCCCTGCCTGGGCTGGCTGTGAGGCCACCTTTGTCCCAGGCCCAGCCTCAAGGC
AAGGAGGGCGCTTCACTGAGGTGTGAATTGTACGTACAGGCTTTTTATATACCAAAAGTATTTTTTGACTAGACCATTCAAAGCTACCCG
AACTATGTTGGAAATTTTTTTTTTCTCATTAAAATACAGGCCCTTAGGCTCTATTTTTCATGTATGAGTCGTGTGTAATTTATGTAAAAA
TGTGTGTACAGACTCACTGATGCAGCACTGTAGCCCATCACCTTGGAGCACTGACTGTACATAGTGTGGTGAAGAAAAGTGAACGCCCTT
GTAGAGCAGCCCGACCACAGGAGCATGGCCGCTGCCAGCCCAGACGCTGCTGACGCTGTGTAAATGTGCACAATAAACCCGTCTCACCCC

>1515_1515_5_ACSL5-PPP1R13B_ACSL5_chr10_114186117_ENST00000393081_PPP1R13B_chr14_104212890_ENST00000202556_length(amino acids)=1389AA_BP=622
MNFLLLFTKMLFIFNFLFSPLPTPALICILTFGAAIFLWLITRPQPVLPLLDLNNQSVGIEGGARKGVSQKNNDLTSCCFSDAKTMYEVF
QRGLAVSDNGPCLGYRKPNQPYRWLSYKQVSDRAEYLGSCLLHKGYKSSPDQFVGIFAQNRPEWIISELACYTYSMVAVPLYDTLGPEAI
VHIVNKADIAMVICDTPQKALVLIGNVEKGFTPSLKVIILMDPFDDDLKQRGEKSGIEILSLYDAENLGKEHFRKPVPPSPEDLSVICFT
SGTTGDPKGAMITHQNIVSNAAAFLKCVEHAYEPTPDDVAISYLPLAHMFERIVQAVVYSCGARVGFFQGDIRLLADDMKTLKPTLFPAV
PRLLNRIYDKVQNEAKTPLKKFLLKLAVSSKFKELQKGIIRHDSFWDKLIFAKIQDSLGGRVRVIVTGAAPMSTSVMTFFRAAMGCQVYE
AYGQTECTGGCTFTLPGDWTSGHVGVPLACNYVKLEDVADMNYFTVNNEGEVCIKGTNVFKGYLKDPEKTQEALDSDGWLHTGDIGRWLP
NGTLKIIDRKKNIFKLAQGEYIAPEKIENIYNRSQPVLQIFVHGESLRSSLVGVVVPDTDVLPSFAAKLGVKGSFEELCQNQLNRVNGTS
SPQSPLSTSGRVAAVGPYIQVPSAGSFPVLGDPIKPQSLSIASNAAHGRSKSANDGNWPTLKQNSSSSVKPVQVAGADWKDPSVEGSVKQ
GTVSSQPVPFSALGPTEKPGIEIGKVPPPIPGVGKQLPPSYGTYPSPTPLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTLLPATGSTPQ
PGSSQQIQQRISVPPSPTYPPAGPPAFPAGDSKPELPLTVAIRPFLADKGSRPQSPRKGPQTVNSSSIYSMYLQQATPPKNYQPAAHSAL
NKSVKAVYGKPVLPSGSTSPSPLPFLHGSLSTGTPQPQPPSESTEKEPEQDGPAAPADGSTVESLPRPLSPTKLTPIVHSPLRYQSDADL
EALRRKLANAPRPLKKRSSITEPEGPGGPNIQKLLYQRFNTLAGGMEGTPFYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAPL
PAEPAPSSDANDNELPSPEPEELICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEAPSPGEEQVPPAPLPPASHPPATSTNKRTNLK
KPNSERTGHGLRVRFNPLALLLDASLEGEFDLVQRIIYEVEDPSKPNDEGITPLHNAVCAGHHHIVKFLLDFGVNVNAADSDGWTPLHCA
ASCNSVHLCKQLVESGAAIFASTISDIETAADKCEEMEEGYIQCSQFLYGVQEKLGVMNKGVAYALWDYEAQNSDELSFHEGDALTILRR

--------------------------------------------------------------
>1515_1515_6_ACSL5-PPP1R13B_ACSL5_chr10_114186117_ENST00000433418_PPP1R13B_chr14_104212890_ENST00000202556_length(transcript)=5825nt_BP=2119nt
TAAAACCAGGAAGTGAAGTCCCCGAGCACGTTAGAAAGCCTGACATGGCCTGACTCGGGACAGCTCAGAGCAGGGCAGAACTGGGGACAC
TCTGGGCCGGCCTTCTGCCTGCATGGACGCTCTGAAGCCACCCTGTCTCTGGAGGAACCACGAGCGAGGGAAGAAGGACAGGGACTCGTG
TGGCAGGAAGAACTCAGAGCCGGGAAGCCCCCATTCACTAGAAGCACTGAGAGATGCGGCCCCCTCGCAGGGTCTGAATTTCCTGCTGCT
GTTCACAAAGATGCTTTTTATCTTTAACTTTTTGTTTTCCCCACTTCCGACCCCGGCGTTGATCTGCATCCTGACATTTGGAGCTGCCAT
CTTCTTGTGGCTGATCACCAGACCTCAACCCGTCTTACCTCTTCTTGACCTGAACAATCAGTCTGTGGGAATTGAGGGAGGAGCACGGAA
GGGGGTTTCCCAGAAGAACAATGACCTAACAAGTTGCTGCTTCTCAGATGCCAAGACTATGTATGAGGTTTTCCAAAGAGGACTCGCTGT
GTCTGACAATGGGCCCTGCTTGGGATATAGAAAACCAAACCAGCCCTACAGATGGCTATCTTACAAACAGGTGTCTGATAGAGCAGAGTA
CCTGGGTTCCTGTCTCTTGCATAAAGGTTATAAATCATCACCAGACCAGTTTGTCGGCATCTTTGCTCAGAATAGGCCAGAGTGGATCAT
CTCCGAATTGGCTTGTTACACGTACTCTATGGTAGCTGTACCTCTGTATGACACCTTGGGACCAGAAGCCATCGTACATATTGTCAACAA
GGCTGATATCGCCATGGTGATCTGTGACACACCCCAAAAGGCATTGGTGCTGATAGGGAATGTAGAGAAAGGCTTCACCCCGAGCCTGAA
GGTGATCATCCTTATGGACCCCTTTGATGATGACCTGAAGCAAAGAGGGGAGAAGAGTGGAATTGAGATCTTATCCCTATATGATGCTGA
GAACCTAGGCAAAGAGCACTTCAGAAAACCTGTGCCTCCTAGCCCAGAAGACCTGAGCGTCATCTGCTTCACCAGTGGGACCACAGGTGA
CCCCAAAGGAGCCATGATAACCCATCAAAATATTGTTTCAAATGCTGCTGCCTTTCTCAAATGTGTGGAGCATGCTTATGAGCCCACTCC
TGATGATGTGGCCATATCCTACCTCCCTCTGGCTCATATGTTTGAGAGGATTGTACAGGCTGTTGTGTACAGCTGTGGAGCCAGAGTTGG
ATTCTTCCAAGGGGATATTCGGTTGCTGGCTGACGACATGAAGACTTTGAAGCCCACATTGTTTCCCGCGGTGCCTCGACTCCTTAACAG
GATCTACGATAAGGTACAAAATGAGGCCAAGACACCCTTGAAGAAGTTCTTGTTGAAGCTGGCTGTTTCCAGTAAATTCAAAGAGCTTCA
AAAGGGTATCATCAGGCATGATAGTTTCTGGGACAAGCTCATCTTTGCAAAGATCCAGGACAGCCTGGGCGGAAGGGTTCGTGTAATTGT
CACTGGAGCTGCCCCCATGTCCACTTCAGTCATGACATTCTTCCGGGCAGCAATGGGATGTCAGGTGTATGAAGCTTATGGTCAAACAGA
ATGCACAGGTGGCTGTACATTTACATTACCTGGGGACTGGACATCAGGTCACGTTGGGGTGCCCCTGGCTTGCAATTACGTGAAGCTGGA
AGATGTGGCTGACATGAACTACTTTACAGTGAATAATGAAGGAGAGGTCTGCATCAAGGGTACAAACGTGTTCAAAGGATACCTGAAGGA
CCCTGAGAAGACACAGGAAGCCCTGGACAGTGATGGCTGGCTTCACACAGGAGACATTGGTCGCTGGCTCCCGAATGGAACTCTGAAGAT
CATCGACCGTAAAAAGAACATTTTCAAGCTGGCCCAAGGAGAATACATTGCACCAGAGAAGATAGAAAATATCTACAACAGGAGTCAACC
AGTGTTACAAATTTTTGTACACGGGGAGAGCTTACGGTCATCCTTAGTAGGAGTGGTGGTTCCTGACACAGATGTACTTCCCTCATTTGC
AGCCAAGCTTGGGGTGAAGGGCTCCTTTGAGGAACTGTGCCAAAACCAACTGAACCGTGTGAATGGCACGTCATCACCACAGTCCCCTCT
GAGCACATCGGGCAGGGTCGCTGCTGTGGGGCCTTATATCCAGGTTCCCAGTGCCGGAAGCTTTCCTGTGCTGGGGGACCCTATAAAGCC
CCAGTCTCTCAGTATTGCCTCAAATGCTGCTCATGGAAGATCCAAATCCGCTAATGATGGAAACTGGCCAACATTAAAACAGAATTCTAG
CTCTTCCGTGAAACCAGTGCAGGTGGCCGGTGCAGACTGGAAGGATCCGAGCGTGGAGGGGTCTGTCAAGCAGGGCACTGTCTCCAGCCA
GCCTGTGCCCTTCTCAGCACTGGGACCCACGGAGAAGCCGGGCATCGAGATTGGTAAAGTGCCACCTCCCATCCCGGGTGTAGGCAAGCA
GCTGCCTCCAAGCTATGGGACATACCCAAGTCCTACACCTCTGGGTCCTGGGTCGACAAGCTCCCTGGAAAGGAGGAAGGAAGGCAGCTT
GCCCAGGCCCAGTGCAGGCCTGCCAAGTCGACAGAGGCCCACCCTGCTGCCCGCCACAGGCAGCACCCCCCAGCCAGGCTCCTCACAACA
GATTCAGCAGAGGATTTCCGTACCGCCAAGTCCCACGTACCCGCCAGCGGGACCACCTGCATTTCCAGCTGGGGACAGCAAGCCTGAACT
CCCACTGACAGTGGCCATTAGGCCTTTCCTGGCTGATAAAGGGTCAAGGCCACAGTCTCCCAGGAAAGGACCCCAGACAGTGAATTCAAG
TTCCATATACTCCATGTACCTCCAGCAAGCCACACCACCTAAGAATTACCAGCCGGCAGCACACAGCGCCTTAAATAAGTCAGTTAAAGC
AGTGTATGGTAAGCCCGTTTTACCTTCGGGTTCAACCTCTCCATCGCCGCTGCCGTTTCTTCACGGGTCACTGTCCACGGGCACACCACA
GCCTCAGCCACCTTCAGAAAGTACTGAGAAAGAGCCTGAGCAGGATGGCCCCGCCGCCCCCGCAGATGGCAGCACCGTGGAGAGCCTGCC
ACGGCCACTCAGCCCCACCAAGCTCACGCCCATCGTGCATTCGCCACTGCGCTACCAGAGTGATGCAGACCTGGAGGCCCTCCGCAGGAA
GCTGGCCAACGCGCCCCGGCCCCTGAAAAAGCGCAGCTCCATCACAGAGCCCGAGGGCCCCGGCGGGCCCAACATCCAGAAGCTGCTGTA
CCAGCGCTTCAACACCCTGGCCGGTGGCATGGAGGGCACCCCTTTCTACCAGCCCAGCCCCTCCCAGGACTTCATGGGCACCTTGGCCGA
TGTGGACAATGGAAACACCAATGCCAATGGAAACCTGGAAGAGCTCCCCCCTGCCCAGCCCACAGCCCCACTCCCCGCTGAGCCTGCCCC
GTCATCAGATGCCAATGATAATGAGTTACCTTCCCCCGAACCAGAGGAGCTCATCTGTCCCCAAACCACCCACCAAACTGCCGAGCCGGC
AGAGGACAATAACAACAACGTGGCCACGGTCCCCACCACGGAGCAGATCCCGAGTCCTGTGGCTGAGGCCCCATCTCCAGGGGAAGAGCA
GGTCCCTCCAGCACCTCTTCCCCCTGCCAGCCACCCTCCTGCCACCTCCACGAACAAGCGGACCAACTTGAAGAAGCCCAACTCGGAGCG
GACGGGGCACGGGCTGAGAGTCCGGTTTAACCCCCTGGCACTGCTCCTAGACGCGTCTCTGGAAGGAGAGTTCGATCTGGTGCAGAGGAT
CATCTATGAGGTGGAAGATCCCAGCAAGCCCAACGACGAAGGGATCACCCCACTGCACAACGCCGTCTGCGCCGGCCACCATCACATCGT
GAAGTTCCTGCTGGATTTTGGTGTCAACGTGAATGCTGCTGATAGTGATGGATGGACGCCGCTGCACTGCGCTGCCTCTTGTAACAGCGT
TCACCTCTGCAAACAGCTGGTGGAGAGTGGTGCCGCCATTTTTGCCTCAACCATAAGCGACATTGAAACTGCTGCAGACAAGTGTGAGGA
GATGGAGGAAGGCTACATCCAGTGCTCCCAGTTTCTATATGGGGTGCAGGAAAAGCTGGGTGTGATGAACAAAGGTGTGGCGTATGCTCT
GTGGGACTACGAGGCCCAGAACAGTGACGAGCTGTCCTTCCACGAAGGGGACGCCCTCACCATCCTGAGGCGCAAGGACGAAAGCGAGAC
TGAGTGGTGGTGGGCTCGCCTTGGAGACCGGGAGGGCTATGTGCCCAAAAACCTGCTGGGGCTGTATCCACGGATCAAACCCCGACAGCG
AACACTCGCCTGAACTTCCTTTTGGAGCACCGCATGGTCTTGCCAGCTACCAGGAGCCACTTAAGAGATTATTGTGCTGTTTTCCAGGAA
AGCTGCAGCTAGAAAATGGTCTTAATGGTGCTCACTTTAGCAGACAGCGTCCACAATGTGAATCCTACAGTTTCCAGGTGAGGCCCTTTC
TCCAGTTTGCCCATTAACTGGGAGAGGTACTTTCGCCTCCAAGGACTGAATTTTGCCAATTACTATAAATCCAAATAAATACCCACTTTC
AAAACACCCACCCCTCTTGCCATTAAGAAGTCCCATAACCCCCGGTTGGTTGCCAGTGAAGACAGAAGCTCTTACTGACTTGGCCCCGAG
GCCATCACCCCCTCCAGCAGTGAACACTGTCCGCCGCTGTGAGGCCTGCTCCCCTGCGACCGCCCTGCCCCCCGTCACCGAATCGGACAC
TCATCCTTTCTCACACTTCCCACACATGATCCTTCTTCCCTTCATCACCAAAGGAGCCTCTGTATGGAAACATGTCCAGTGTTGCTGCCC
AGTGTGTATGCCTCCCAGTACCCACTCTGCTCGGCCGCCTTGGGGGTTCCGCTTCCTGTTCCAGTTCACCTAAAGGCTGATTGTGCAGGC
CCAGCACTGTGGCTGGACTGCCGCGCCACGGGCACCAGGACCCCTAAGACCAAGTGACAACTGGGAGAGCCTCAGCATATACTCTTCTCC
TCCGATCTCACAGCCTGTCATGCTGCTCAGTGTGGTTCTCACCCCTGCAAGCTCAAATTCAGTTCCCTGAATGGAGTCAGGTGCTGGAGG
CCGTGGCAGCGGAGGGTGGTTGGGGTTGGGGCTGGGGGTGGACTGGTGTGAGGGCAGACCAGGGCCAGGTAGACGGGGCTGTTTGGTGCC
TGAAGGATGGCAGACGCCTGGTGTCAGGAGGGGCCGCCACCAAGGAGCAGCAGCTGGGGCAGAGGAGCTGGGGTCAGGGGCCACCCCTCT
CTGCCGATCTCCCTGCCTGGGCTGGCTGTGAGGCCACCTTTGTCCCAGGCCCAGCCTCAAGGCAAGGAGGGCGCTTCACTGAGGTGTGAA
TTGTACGTACAGGCTTTTTATATACCAAAAGTATTTTTTGACTAGACCATTCAAAGCTACCCGAACTATGTTGGAAATTTTTTTTTTCTC
ATTAAAATACAGGCCCTTAGGCTCTATTTTTCATGTATGAGTCGTGTGTAATTTATGTAAAAATGTGTGTACAGACTCACTGATGCAGCA
CTGTAGCCCATCACCTTGGAGCACTGACTGTACATAGTGTGGTGAAGAAAAGTGAACGCCCTTGTAGAGCAGCCCGACCACAGGAGCATG

>1515_1515_6_ACSL5-PPP1R13B_ACSL5_chr10_114186117_ENST00000433418_PPP1R13B_chr14_104212890_ENST00000202556_length(amino acids)=1457AA_BP=690
MTRDSSEQGRTGDTLGRPSACMDALKPPCLWRNHERGKKDRDSCGRKNSEPGSPHSLEALRDAAPSQGLNFLLLFTKMLFIFNFLFSPLP
TPALICILTFGAAIFLWLITRPQPVLPLLDLNNQSVGIEGGARKGVSQKNNDLTSCCFSDAKTMYEVFQRGLAVSDNGPCLGYRKPNQPY
RWLSYKQVSDRAEYLGSCLLHKGYKSSPDQFVGIFAQNRPEWIISELACYTYSMVAVPLYDTLGPEAIVHIVNKADIAMVICDTPQKALV
LIGNVEKGFTPSLKVIILMDPFDDDLKQRGEKSGIEILSLYDAENLGKEHFRKPVPPSPEDLSVICFTSGTTGDPKGAMITHQNIVSNAA
AFLKCVEHAYEPTPDDVAISYLPLAHMFERIVQAVVYSCGARVGFFQGDIRLLADDMKTLKPTLFPAVPRLLNRIYDKVQNEAKTPLKKF
LLKLAVSSKFKELQKGIIRHDSFWDKLIFAKIQDSLGGRVRVIVTGAAPMSTSVMTFFRAAMGCQVYEAYGQTECTGGCTFTLPGDWTSG
HVGVPLACNYVKLEDVADMNYFTVNNEGEVCIKGTNVFKGYLKDPEKTQEALDSDGWLHTGDIGRWLPNGTLKIIDRKKNIFKLAQGEYI
APEKIENIYNRSQPVLQIFVHGESLRSSLVGVVVPDTDVLPSFAAKLGVKGSFEELCQNQLNRVNGTSSPQSPLSTSGRVAAVGPYIQVP
SAGSFPVLGDPIKPQSLSIASNAAHGRSKSANDGNWPTLKQNSSSSVKPVQVAGADWKDPSVEGSVKQGTVSSQPVPFSALGPTEKPGIE
IGKVPPPIPGVGKQLPPSYGTYPSPTPLGPGSTSSLERRKEGSLPRPSAGLPSRQRPTLLPATGSTPQPGSSQQIQQRISVPPSPTYPPA
GPPAFPAGDSKPELPLTVAIRPFLADKGSRPQSPRKGPQTVNSSSIYSMYLQQATPPKNYQPAAHSALNKSVKAVYGKPVLPSGSTSPSP
LPFLHGSLSTGTPQPQPPSESTEKEPEQDGPAAPADGSTVESLPRPLSPTKLTPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSSITE
PEGPGGPNIQKLLYQRFNTLAGGMEGTPFYQPSPSQDFMGTLADVDNGNTNANGNLEELPPAQPTAPLPAEPAPSSDANDNELPSPEPEE
LICPQTTHQTAEPAEDNNNNVATVPTTEQIPSPVAEAPSPGEEQVPPAPLPPASHPPATSTNKRTNLKKPNSERTGHGLRVRFNPLALLL
DASLEGEFDLVQRIIYEVEDPSKPNDEGITPLHNAVCAGHHHIVKFLLDFGVNVNAADSDGWTPLHCAASCNSVHLCKQLVESGAAIFAS
TISDIETAADKCEEMEEGYIQCSQFLYGVQEKLGVMNKGVAYALWDYEAQNSDELSFHEGDALTILRRKDESETEWWWARLGDREGYVPK

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Fusion Gene PPI Analysis for ACSL5-PPP1R13B


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ACSL5-PPP1R13B


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ACSL5-PPP1R13B


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneACSL5C0003865Arthritis, Adjuvant-Induced1CTD_human
HgeneACSL5C0971858Arthritis, Collagen-Induced1CTD_human
HgeneACSL5C0993582Arthritis, Experimental1CTD_human