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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:GALNT7-GAB1 (FusionGDB2 ID:HG51809TG2549) |
Fusion Gene Summary for GALNT7-GAB1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: GALNT7-GAB1 | Fusion gene ID: hg51809tg2549 | Hgene | Tgene | Gene symbol | GALNT7 | GAB1 | Gene ID | 51809 | 2549 |
| Gene name | polypeptide N-acetylgalactosaminyltransferase 7 | GRB2 associated binding protein 1 | |
| Synonyms | GALNAC-T7|GalNAcT7 | DFNB26 | |
| Cytomap | ('GALNT7')('GAB1') 4q34.1 | 4q31.21 | |
| Type of gene | protein-coding | protein-coding | |
| Description | N-acetylgalactosaminyltransferase 7UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 7UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7)polypeptide GalNAc transferase 7pp-GaNTase 7protein-UDP acetylg | GRB2-associated-binding protein 1GRB2-associated binder 1deafness, autosomal recessive 26growth factor receptor bound protein 2-associated protein 1symbol withdrawn, see GAB1 | |
| Modification date | 20200313 | 20200327 | |
| UniProtAcc | Q86SF2 | Q13480 | |
| Ensembl transtripts involved in fusion gene | ENST00000265000, ENST00000512285, ENST00000502407, | ||
| Fusion gene scores | * DoF score | 8 X 6 X 5=240 | 8 X 7 X 5=280 |
| # samples | 11 | 9 | |
| ** MAII score | log2(11/240*10)=-1.12553088208386 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(9/280*10)=-1.63742992061529 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: GALNT7 [Title/Abstract] AND GAB1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | GALNT7(174090112)-GAB1(144336630), # samples:3 | ||
| Anticipated loss of major functional domain due to fusion event. | GALNT7-GAB1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. GALNT7-GAB1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. GALNT7-GAB1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. GALNT7-GAB1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene breakpoints across GALNT7 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across GAB1 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | PRAD | TCGA-VN-A943-01A | GALNT7 | chr4 | 174090112 | - | GAB1 | chr4 | 144336630 | + |
| ChimerDB4 | PRAD | TCGA-VN-A943-01A | GALNT7 | chr4 | 174090112 | + | GAB1 | chr4 | 144336630 | + |
| ChimerDB4 | PRAD | TCGA-VN-A943 | GALNT7 | chr4 | 174090112 | + | GAB1 | chr4 | 144336630 | + |
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Fusion Gene ORF analysis for GALNT7-GAB1 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-5UTR | ENST00000265000 | ENST00000505913 | GALNT7 | chr4 | 174090112 | + | GAB1 | chr4 | 144336630 | + |
| 5CDS-5UTR | ENST00000512285 | ENST00000505913 | GALNT7 | chr4 | 174090112 | + | GAB1 | chr4 | 144336630 | + |
| 5CDS-intron | ENST00000265000 | ENST00000515388 | GALNT7 | chr4 | 174090112 | + | GAB1 | chr4 | 144336630 | + |
| 5CDS-intron | ENST00000512285 | ENST00000515388 | GALNT7 | chr4 | 174090112 | + | GAB1 | chr4 | 144336630 | + |
| In-frame | ENST00000265000 | ENST00000262994 | GALNT7 | chr4 | 174090112 | + | GAB1 | chr4 | 144336630 | + |
| In-frame | ENST00000265000 | ENST00000262995 | GALNT7 | chr4 | 174090112 | + | GAB1 | chr4 | 144336630 | + |
| In-frame | ENST00000512285 | ENST00000262994 | GALNT7 | chr4 | 174090112 | + | GAB1 | chr4 | 144336630 | + |
| In-frame | ENST00000512285 | ENST00000262995 | GALNT7 | chr4 | 174090112 | + | GAB1 | chr4 | 144336630 | + |
| intron-3CDS | ENST00000502407 | ENST00000262994 | GALNT7 | chr4 | 174090112 | + | GAB1 | chr4 | 144336630 | + |
| intron-3CDS | ENST00000502407 | ENST00000262995 | GALNT7 | chr4 | 174090112 | + | GAB1 | chr4 | 144336630 | + |
| intron-5UTR | ENST00000502407 | ENST00000505913 | GALNT7 | chr4 | 174090112 | + | GAB1 | chr4 | 144336630 | + |
| intron-intron | ENST00000502407 | ENST00000515388 | GALNT7 | chr4 | 174090112 | + | GAB1 | chr4 | 144336630 | + |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000265000 | GALNT7 | chr4 | 174090112 | + | ENST00000262995 | GAB1 | chr4 | 144336630 | + | 7691 | 209 | 83 | 2311 | 742 |
| ENST00000265000 | GALNT7 | chr4 | 174090112 | + | ENST00000262994 | GAB1 | chr4 | 144336630 | + | 2483 | 209 | 83 | 2221 | 712 |
| ENST00000512285 | GALNT7 | chr4 | 174090112 | + | ENST00000262995 | GAB1 | chr4 | 144336630 | + | 7633 | 151 | 25 | 2253 | 742 |
| ENST00000512285 | GALNT7 | chr4 | 174090112 | + | ENST00000262994 | GAB1 | chr4 | 144336630 | + | 2425 | 151 | 25 | 2163 | 712 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000265000 | ENST00000262995 | GALNT7 | chr4 | 174090112 | + | GAB1 | chr4 | 144336630 | + | 8.77E-05 | 0.99991226 |
| ENST00000265000 | ENST00000262994 | GALNT7 | chr4 | 174090112 | + | GAB1 | chr4 | 144336630 | + | 0.000863291 | 0.99913675 |
| ENST00000512285 | ENST00000262995 | GALNT7 | chr4 | 174090112 | + | GAB1 | chr4 | 144336630 | + | 8.69E-05 | 0.9999131 |
| ENST00000512285 | ENST00000262994 | GALNT7 | chr4 | 174090112 | + | GAB1 | chr4 | 144336630 | + | 0.000865896 | 0.9991341 |
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Fusion Genomic Features for GALNT7-GAB1 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| GALNT7 | chr4 | 174090112 | + | GAB1 | chr4 | 144336629 | + | 4.73E-05 | 0.9999527 |
| GALNT7 | chr4 | 174090112 | + | GAB1 | chr4 | 144336629 | + | 4.73E-05 | 0.9999527 |
| GALNT7 | chr4 | 174090112 | + | GAB1 | chr4 | 144336629 | + | 4.73E-05 | 0.9999527 |
| GALNT7 | chr4 | 174090112 | + | GAB1 | chr4 | 144336629 | + | 4.73E-05 | 0.9999527 |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for GALNT7-GAB1 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr4:174090112/chr4:144336630) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| GALNT7 | GAB1 |
| FUNCTION: Glycopeptide transferase involved in O-linked oligosaccharide biosynthesis, which catalyzes the transfer of an N-acetyl-D-galactosamine residue to an already glycosylated peptide. In contrast to other proteins of the family, it does not act as a peptide transferase that transfers GalNAc onto serine or threonine residue on the protein receptor, but instead requires the prior addition of a GalNAc on a peptide before adding additional GalNAc moieties. Some peptide transferase activity is however not excluded, considering that its appropriate peptide substrate may remain unidentified. {ECO:0000269|PubMed:10544240, ECO:0000269|PubMed:11925450}. | FUNCTION: Adapter protein that plays a role in intracellular signaling cascades triggered by activated receptor-type kinases. Plays a role in FGFR1 signaling. Probably involved in signaling by the epidermal growth factor receptor (EGFR) and the insulin receptor (INSR). Involved in the MET/HGF-signaling pathway (PubMed:29408807). {ECO:0000269|PubMed:29408807}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | GALNT7 | chr4:174090112 | chr4:144336630 | ENST00000265000 | + | 1 | 12 | 1_6 | 42 | 658.0 | Topological domain | Cytoplasmic |
| Hgene | GALNT7 | chr4:174090112 | chr4:144336630 | ENST00000265000 | + | 1 | 12 | 7_29 | 42 | 658.0 | Transmembrane | Helical%3B Signal-anchor for type II membrane protein |
| Tgene | GAB1 | chr4:174090112 | chr4:144336630 | ENST00000262994 | 0 | 10 | 449_540 | 24 | 695.0 | Compositional bias | Note=Pro-rich | |
| Tgene | GAB1 | chr4:174090112 | chr4:144336630 | ENST00000262995 | 0 | 11 | 449_540 | 24 | 725.0 | Compositional bias | Note=Pro-rich |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | GALNT7 | chr4:174090112 | chr4:144336630 | ENST00000265000 | + | 1 | 12 | 532_652 | 42 | 658.0 | Domain | Ricin B-type lectin |
| Hgene | GALNT7 | chr4:174090112 | chr4:144336630 | ENST00000265000 | + | 1 | 12 | 206_317 | 42 | 658.0 | Region | Note=Catalytic subdomain A |
| Hgene | GALNT7 | chr4:174090112 | chr4:144336630 | ENST00000265000 | + | 1 | 12 | 381_443 | 42 | 658.0 | Region | Note=Catalytic subdomain B |
| Hgene | GALNT7 | chr4:174090112 | chr4:144336630 | ENST00000265000 | + | 1 | 12 | 30_657 | 42 | 658.0 | Topological domain | Lumenal |
| Tgene | GAB1 | chr4:174090112 | chr4:144336630 | ENST00000262994 | 0 | 10 | 5_116 | 24 | 695.0 | Domain | PH | |
| Tgene | GAB1 | chr4:174090112 | chr4:144336630 | ENST00000262995 | 0 | 11 | 5_116 | 24 | 725.0 | Domain | PH |
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Fusion Gene Sequence for GALNT7-GAB1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >32304_32304_1_GALNT7-GAB1_GALNT7_chr4_174090112_ENST00000265000_GAB1_chr4_144336630_ENST00000262994_length(transcript)=2483nt_BP=209nt AGAGCCGGAGGAGGGGGAAGGAGGGAGGGGAGAGCGGTGGCGGCGGCTGCGCCGGGCTGTGAGTCTCTCGCCGCCGGAGGAAGATGAGGC TGAAGATTGGGTTCATCTTACGCAGTTTGCTGGTGGTGGGAAGCTTCCTGGGGCTAGTGGTCCTCTGGTCTTCCCTGACCCCGCGGCCGG ACGACCCAAGCCCGCTGAGCAGGATGAGGGCATGGAAGAGGAGATGGTTCGTGTTACGCAGTGGCCGTTTAACTGGAGATCCAGATGTTT TGGAATATTACAAAAATGATCATGCCAAGAAGCCTATTCGTATTATTGATTTAAATTTATGTCAACAAGTAGATGCTGGATTGACATTTA ACAAAAAAGAGTTTGAAAACAGCTACATTTTTGATATCAACACTATTGACCGGATTTTCTACTTGGTAGCAGACAGCGAGGAGGAGATGA ATAAGTGGGTTCGTTGTATTTGTGACATCTGTGGGTTTAATCCAACAGAAGAAGATCCTGTGAAGCCACCTGGCAGCTCTTTACAAGCAC CAGCTGATTTACCTTTAGCTATAAATACAGCACCACCATCCACCCAGGCAGATTCATCCTCTGCTACTCTACCTCCTCCATATCAGCTAA TCAATGTTCCACCACACCTGGAAACTCTTGGCATTCAGGAGGATCCTCAAGACTACCTGTTGCTCATCAACTGTCAAAGCAAGAAGCCCG AACCCACCAGAACGCATGCTGATTCTGCAAAATCCACCTCTTCTGAAACAGACTGCAATGATAACGTCCCTTCTCATAAAAATCCTGCTT CCTCCCAGAGCAAACATGGAATGAATGGCTTTTTTCAGCAGCAAATGATATACGACTCTCCACCTTCACGTGCCCCATCTGCTTCAGTTG ACTCCAGCCTTTATAACCTGCCCAGGAGTTATTCCCATGATGTTTTACCAAAGGTGTCTCCATCAAGTACTGAAGCAGATGGAGAACTCT ATGTTTTTAATACCCCATCTGGGACATCGAGTGTAGAGACTCAAATGAGGCATGTATCTATTAGTTATGACATTCCTCCAACACCTGGTA ATACTTATCAGATTCCACGAACATTTCCAGAAGGAACCTTGGGACAGACATCAAAGCTAGACACTATTCCAGATATTCCTCCACCTCGGC CACCGAAACCACATCCAGCTCATGACCGATCTCCTGTGGAAACGTGTAGTATCCCACGCACCGCCTCAGACACTGACAGTAGTTACTGTA TCCCTACAGCAGGGATGTCGCCTTCACGTAGTAATACCATTTCCACTGTGGATTTAAACAAATTGCGAAAAGATGCTAGTTCTCAAGACT GCTATGATATTCCACGAGCATTTCCAAGTGATAGATCTAGTTCACTTGAAGGCTTCCATAACCACTTTAAAGTCAAAAATGTGTTGACAG TGGGAAGTGTTTCAAGTGAAGAACTGGATGAAAATTACGTCCCAATGAATCCCAATTCACCACCACGACAACATTCCAGCAGTTTTACAG AACCAATTCAGGAAGCAAATTATGTGCCAATGACTCCAGGAACATTTGATTTTTCCTCATTTGGAATGCAAGTTCCTCCTCCTGCTCATA TGGGCTTCAGGTCCAGCCCAAAAACCCCTCCCAGAAGGCCAGTTCCTGTTGCAGACTGTGAACCACCCCCCGTGGATAGGAACCTCAAGC CAGACAGAAAAGTCAAGCCAGCGCCTTTAGAAATAAAACCTTTGCCAGAATGGGAAGAATTACAAGCCCCAGTTAGATCTCCCATCACTA GGAGTTTTGCTCGAGACTCTTCCAGGTTTCCCATGTCCCCCCGACCAGATTCAGTGCATAGCACAACTTCAAGCAGTGACTCACACGACA GTGAAGAGAATTATGTTCCCATGAACCCAAACCTGTCCAGTGAAGACCCAAATCTCTTTGGCAGTAACAGTCTTGATGGAGGAAGCAGCC CTATGATCAAGCCCAAAGGAGACAAACAGGTGGAATACTTAGATCTCGACTTAGATTCTGGGAAATCCACACCACCACGTAAGCAAAAGA GCAGTGGCTCAGGCAGCAGTGTAGCAGATGAGAGAGTGGATTATGTTGTTGTTGACCAACAGAAGACCTTGGCTCTAAAGAGTACCCGGG AAGCCTGGACAGATGGGAGACAGTCCACAGAATCAGAAACGCCAGCGAAGAGTGTGAAATGAAAATATTGCCTTGCCATTTCTGAACAAA AGAAAACTGAATTGTAAAGATAAATCCCTTTTGAAGAATGACTTGACACTTCCACTCTAGGTAGATCCTCAAATGAGTAGAGTTGAAGTC AAAGGACCTTTCTGACATAATCAAGCAATTTAGACTTAAGTGGTGCTTTGTGGTATCTGAACAATTCATAACATGTAAATAATGTGGGAA >32304_32304_1_GALNT7-GAB1_GALNT7_chr4_174090112_ENST00000265000_GAB1_chr4_144336630_ENST00000262994_length(amino acids)=712AA_BP=20 MRLKIGFILRSLLVVGSFLGLVVLWSSLTPRPDDPSPLSRMRAWKRRWFVLRSGRLTGDPDVLEYYKNDHAKKPIRIIDLNLCQQVDAGL TFNKKEFENSYIFDINTIDRIFYLVADSEEEMNKWVRCICDICGFNPTEEDPVKPPGSSLQAPADLPLAINTAPPSTQADSSSATLPPPY QLINVPPHLETLGIQEDPQDYLLLINCQSKKPEPTRTHADSAKSTSSETDCNDNVPSHKNPASSQSKHGMNGFFQQQMIYDSPPSRAPSA SVDSSLYNLPRSYSHDVLPKVSPSSTEADGELYVFNTPSGTSSVETQMRHVSISYDIPPTPGNTYQIPRTFPEGTLGQTSKLDTIPDIPP PRPPKPHPAHDRSPVETCSIPRTASDTDSSYCIPTAGMSPSRSNTISTVDLNKLRKDASSQDCYDIPRAFPSDRSSSLEGFHNHFKVKNV LTVGSVSSEELDENYVPMNPNSPPRQHSSSFTEPIQEANYVPMTPGTFDFSSFGMQVPPPAHMGFRSSPKTPPRRPVPVADCEPPPVDRN LKPDRKVKPAPLEIKPLPEWEELQAPVRSPITRSFARDSSRFPMSPRPDSVHSTTSSSDSHDSEENYVPMNPNLSSEDPNLFGSNSLDGG -------------------------------------------------------------- >32304_32304_2_GALNT7-GAB1_GALNT7_chr4_174090112_ENST00000265000_GAB1_chr4_144336630_ENST00000262995_length(transcript)=7691nt_BP=209nt AGAGCCGGAGGAGGGGGAAGGAGGGAGGGGAGAGCGGTGGCGGCGGCTGCGCCGGGCTGTGAGTCTCTCGCCGCCGGAGGAAGATGAGGC TGAAGATTGGGTTCATCTTACGCAGTTTGCTGGTGGTGGGAAGCTTCCTGGGGCTAGTGGTCCTCTGGTCTTCCCTGACCCCGCGGCCGG ACGACCCAAGCCCGCTGAGCAGGATGAGGGCATGGAAGAGGAGATGGTTCGTGTTACGCAGTGGCCGTTTAACTGGAGATCCAGATGTTT TGGAATATTACAAAAATGATCATGCCAAGAAGCCTATTCGTATTATTGATTTAAATTTATGTCAACAAGTAGATGCTGGATTGACATTTA ACAAAAAAGAGTTTGAAAACAGCTACATTTTTGATATCAACACTATTGACCGGATTTTCTACTTGGTAGCAGACAGCGAGGAGGAGATGA ATAAGTGGGTTCGTTGTATTTGTGACATCTGTGGGTTTAATCCAACAGAAGAAGATCCTGTGAAGCCACCTGGCAGCTCTTTACAAGCAC CAGCTGATTTACCTTTAGCTATAAATACAGCACCACCATCCACCCAGGCAGATTCATCCTCTGCTACTCTACCTCCTCCATATCAGCTAA TCAATGTTCCACCACACCTGGAAACTCTTGGCATTCAGGAGGATCCTCAAGACTACCTGTTGCTCATCAACTGTCAAAGCAAGAAGCCCG AACCCACCAGAACGCATGCTGATTCTGCAAAATCCACCTCTTCTGAAACAGACTGCAATGATAACGTCCCTTCTCATAAAAATCCTGCTT CCTCCCAGAGCAAACATGGAATGAATGGCTTTTTTCAGCAGCAAATGATATACGACTCTCCACCTTCACGTGCCCCATCTGCTTCAGTTG ACTCCAGCCTTTATAACCTGCCCAGGAGTTATTCCCATGATGTTTTACCAAAGGTGTCTCCATCAAGTACTGAAGCAGATGGAGAACTCT ATGTTTTTAATACCCCATCTGGGACATCGAGTGTAGAGACTCAAATGAGGCATGTATCTATTAGTTATGACATTCCTCCAACACCTGGTA ATACTTATCAGATTCCACGAACATTTCCAGAAGGAACCTTGGGACAGACATCAAAGCTAGACACTATTCCAGATATTCCTCCACCTCGGC CACCGAAACCACATCCAGCTCATGACCGATCTCCTGTGGAAACGTGTAGTATCCCACGCACCGCCTCAGACACTGACAGTAGTTACTGTA TCCCTACAGCAGGGATGTCGCCTTCACGTAGTAATACCATTTCCACTGTGGATTTAAACAAATTGCGAAAAGATGCTAGTTCTCAAGACT GCTATGATATTCCACGAGCATTTCCAAGTGATAGATCTAGTTCACTTGAAGGCTTCCATAACCACTTTAAAGTCAAAAATGTGTTGACAG TGGGAAGTGTTTCAAGTGAAGAACTGGATGAAAATTACGTCCCAATGAATCCCAATTCACCACCACGACAACATTCCAGCAGTTTTACAG AACCAATTCAGGAAGCAAATTATGTGCCAATGACTCCAGGAACATTTGATTTTTCCTCATTTGGAATGCAAGTTCCTCCTCCTGCTCATA TGGGCTTCAGGTCCAGCCCAAAAACCCCTCCCAGAAGGCCAGTTCCTGTTGCAGACTGTGAACCACCCCCCGTGGATAGGAACCTCAAGC CAGACAGAAAAGGTCAAAGTCCTAAAATTTTAAGACTCAAACCCCATGGTTTAGAGCGAACTGATTCACAAACCATAGGTGACTTTGCTA CAAGAAGAAAGGTCAAGCCAGCGCCTTTAGAAATAAAACCTTTGCCAGAATGGGAAGAATTACAAGCCCCAGTTAGATCTCCCATCACTA GGAGTTTTGCTCGAGACTCTTCCAGGTTTCCCATGTCCCCCCGACCAGATTCAGTGCATAGCACAACTTCAAGCAGTGACTCACACGACA GTGAAGAGAATTATGTTCCCATGAACCCAAACCTGTCCAGTGAAGACCCAAATCTCTTTGGCAGTAACAGTCTTGATGGAGGAAGCAGCC CTATGATCAAGCCCAAAGGAGACAAACAGGTGGAATACTTAGATCTCGACTTAGATTCTGGGAAATCCACACCACCACGTAAGCAAAAGA GCAGTGGCTCAGGCAGCAGTGTAGCAGATGAGAGAGTGGATTATGTTGTTGTTGACCAACAGAAGACCTTGGCTCTAAAGAGTACCCGGG AAGCCTGGACAGATGGGAGACAGTCCACAGAATCAGAAACGCCAGCGAAGAGTGTGAAATGAAAATATTGCCTTGCCATTTCTGAACAAA AGAAAACTGAATTGTAAAGATAAATCCCTTTTGAAGAATGACTTGACACTTCCACTCTAGGTAGATCCTCAAATGAGTAGAGTTGAAGTC AAAGGACCTTTCTGACATAATCAAGCAATTTAGACTTAAGTGGTGCTTTGTGGTATCTGAACAATTCATAACATGTAAATAATGTGGGAA AATAGTATTGTTTAGCTCCCAGAGAAACATTTGTTCCACAGTTAACACACTCGTAGTATTACTGTATTTATGCACTTTTTCATCTAAAAC ATTGTTCTGGGTTTTCCCAATGTACCTTACCATAATTCCTTTGGGAGTTCTTGTTTTTTGTCACACTACTTTATATAACAATACTAAGTC AACTAAGCTACTTTTAGATTTGGAAATTGCTGTTTACAGTCTAACAACATTAAAATGAGAGGTAGATTCACAAGTTAGCTTTCTACCTGA AGCTTCAGGTGATAACCATTAGCTTATACTTGGACTCATCATTTGTTGCCTTCCAAAATGCTGAGGATAATGTATGTACTGGTGTCAGGA CCTAGTTCTCTGGTTAATGTACATTTAGTTTTTAATGGTGGAACTTTGTTATATTTTGTTAATTACAGTGTTTTTGGTTCATTGAGTGAA GATTCTGCCGGGTGGGATCTTGCACCTTTGAAAGACTGAATAATTACACTACCAAGTAAGCCTGCAAATCATTGATGGCATGCAGTGATG ATGTGCTCTTACACTTGTTAACATGTATTAAGTGTTATTTGCAAAAGGTAGATTATGTAACCAATCAGGTACGTACCAGGCAGTGATGTG CTAATACACTGATCAGGTTTAGACAATGAGCTTTGGTTGTGTTCTTGTTAGTCCTAATATTGGTTTTCAGTTTGGAATTAATAAAGCAGT TGACATTCACTGTTAGTTACAGCAACATACTGTGATTTTTAATTAGATAGTAATTCAGATTTATTACTCTATGAAATTCTGTCTTTTGAC ACCATAGTGCCCTTTCTATGATTTTTTTTACTTAATATTCTTCTTGGCCTTATATTTAATTCCCTATGCAATTAATATTTTATATCTGCA TTTTTTTAAAAAAAATAGATGTTATATAAGTGATTCTCGTATGTAGCACCTGTTGCTTTTCCACTGAAAGAATTACGGATTTTGTACTGT GATTTATATTCACTGCCCCAATTCAAGAAATATTGGAGCCTTGCTACAATGTGAAATGTTATAGTCATGGACTCCTTCCAACCAGATTTC TGAAAACACCAGAGGGATGGTATAATTCTGTCTCACCTATAACATGGTCCTGTGACATAGATATTAAGACCACAAGTTGTAGTGAGGCTA CAATTATATTCGTCTGTCTTGGCTTTGCAACATAATTTAGAAAGCACGTATAGTTGTTTTTTAACCAAGTTACATACAATCTCATGTACT GATTTGAGACTTATAACAATTTTTGGAGGGGGCATAGAGAAAGGAGTGCCCACAGTTGAGGCATGACCCCCTCCATTCAGACCTCTAACT GTTGCCTGAGTACACAGATGTGCCCTGATTTCTGGCCCATTGGCCATAGTACTGTGCCTAATCAATGTAATAGGTTTATTTTCCCAATCC TCAAACTAAAAATGTTCATAACAAGATGAATTGTAGACTAGTAACATTTGATGCTTTTAAATATTTGCTTCTTTTTAAACAAAAACTAAA ACCCAGAAGTGAATTTTTAGGTGGATTTTTAAATAAAAAAGATTGATTGAGTTTGGTGTGCAAGCTGTTTTATAATGAAACAACAAAATG AAATCTAAAATCCTGAAATGTGCCTAAACTATCAAAACACACGATACAGCTAATGTGTAAAGATGCTAAATTCTGTTACTTGGAGGATGA ATATATTTAAGATTTAAAACACAATAATAAATACATGATTAATTCAAAAATAAAAATCTTTACAGCTGCCTATCAAGGGTCTAAAGCACT TAATGAATGTTTTTAGTCTAACTTATCATTAACTTTTTACAAGTCACCATATTTGAAGATCTGTAGCACTCTGATTTTCAGAAAATTTTT CATTCTGAATAATTTAAAAATGGTGATGTATTAGAAAGGCAGTTTGCTTTAGAAAACTAAATCACATTGAACATTGTATTAGAGAATTAA ATTAAAAGTTTCTTACAGAGCAGTATTTTCCAAACATTTTTAGCACTAGAATCTTTTTAGATGAAATTTTATGTATAACCCCAATACATA AAGCCTGAAAACTCAATTTTATCAATATAAATGTATTTTGGGTTCACATTTATGCTTATTCATTTTGGCTCATTACTAAGCATAATAAGA TTCTGAGTTATTTCTGAATAACACAAATGTGGAGTTATACATAGTTGATGAAACCAGCAGCCAATTTATAGCTATGCCCTGTTTTATTTG TATACTATCAAGAAAATTTTGATTCACACAAATGTAAGCAAAAATAATAGGTTTTAAACATACATCTCAGGAAATTCTTTAATTAGAGAT AGCTAAAGTTATTCAAGGTCTATACAAAAATAAGTTATCCTGGTAGTGGAAGTTAATACATAAGCAGTCTCCAGTGTGGTAAAGTAGGGT ATGTAACACATCAGAATGTGCGTTTTTATTAGGTTTTAAAATATGCACGTATAAAAACTAAATTTGAATCAAACCCTTTTAACTCACCTC CAAGAAGCTAGACTTTGGCCAGGAATGGGCTAAAAACCACTGGTTAACGATGTGACAGTTATGATCTTGGAGATTGGAAATCTTTCTTCC ACATTAGAGTTCTTTACCTTAATTCCTTATTCTGAAAAATTGTAAGATTTTATGAAGGTTTGAATACTGAAGCACAGTTCTGCTTTCAAA AATTAAAATTCAAACTTGAAAAAGCTGTTTAACCCATGGAAGATATCATTTAGTAAGATGTAAAAGATTTTTTAAATCTACACTTCAGTT TATACATCTTTATCATTATCAATACTATATAAGTTACTGTGAGCATTTTAGAGAATTCCATAAAGGTACTATGAGTGTGTCTGTATGTGT GTGTATATATAGCATTGTATTTAATCATAGACTAAATTTAATTTGATATAGAAATACTACTTTACTTGTACATTAAGGTCATAATTTCTG CTGGACTCTTTTATATTTAATTAATGGGGATTATAGTCTTCCTTCATAAATGCATTTAAACCTGAAATTGAACACCAGTGTTTTTCTTTT TCTACTTATGGGAAGTTGTCTGCTTCCCCCTTTAGAGAAAACAGTATTTTTATATTTTGTTAAAATATTAACTACTTTATGCCTACACAC TATGCTGTAGATACTGATCATAATTCTTGGGTGTTCACAAACACTCCTAGTGCCTCTTTTTTGGCCCGTTGAAAGTGTTGGTATTACTAC TTTCACTACAGAGCCTTTGGCCCTCTAATAATGCTGAGGTGGGCTGATCCTTCCCATTTCTGTCTTCGGGTCATTCTGGTAGGTCTTCTC CTCCACTGTCAAGTAAGCAATCAGGTCCGTGACAGGGATTGGACATATGAACAAATTAAGTGGATACACACAGTGAGAAAGATACATGCA TTCTATGGTAACAACTACTGTCAATAACATCTGATGTTACATGCACATTTATATATATATAATTTTAAAAACTGAACTATGAGAAGCCAT GGTATAAATGAATATTGTGGACATCATGGACTTGATATGATAGAAATCAATTGTCAGCTTGAGAAAGTTGTTTTTAATCTGTCTAAATAG TTCATGCATTACTACAGTTAAAAATAGTTTCATTTGTCTTCTATAGACTTAATTTTATTCCGGTTCAGTATAATCTCTGTTAACAGAGTT TCAGCAAACTGATTGGTCAAGGTATTAACATAGCTTCTACTTCCTTTACTTAAAAAGATGTGGTTTTATGTAAGTTCTTGATTACTGATG ATCATCCCAAATTTTGACAACAAAATCATATGTATAAATTTATTTCTCCCCTCTTGTTCATCATCTTTTGTAAAGGTCCCATTGTAGATC TTTTCTGCTACCAAATAAAACTTTTCAAACAATTTGGTTTCAAGACCTTAAATAGACAAGTTGGATACTAAGATTGTGAACTGATAAGGA CATATAAATTTATATTTCCAGCCCTTCCTTAGAGTCTTTATCTGCATCAAAAACCCAATTCTGCCATTAACTGTGCTTCCCAGTCCCACC TCTATATGTCACTCATTTTCTGCAACAAAGATCTCACTAAATCATGTTGAAACACAAGTCATGATCCTCTCTAAGTAAATAGAAAAAGCT CCCTGGAAAAACTCTGTTGCCACATGCACGTGCCCTGTTACTCCTCCAGCCAGCCAGTGCTGCCAGCATTTTATTGTGTAAAAGTCCAAA TAAATAAGGGCCTGCATGCAACCTTTATCTTCAGAAACTAGGTTTTATATGTAAAATGTGACTTGGGAAATGATTCTGTTTATTAACTGG CTGGGATTTTTCATTTCTATGAAAGTTTCAAACATCTCCAGTACTTTATAAAATCCCAACAATTGCTGTAAGTCAGCACTTTGGTCCACT CAGCCCACCCAGCCCACTTGCAACTCTGACTCTTCACTGAATCATATTTGGGAAGTTTGGGTAGGGTGAGGCTATCTTCTTCAAGATTAT TTTCTCATATGTCTGTCTGTCACCTTGTAAACCATGAGACTCCTGGGTATTTGCATGTAACTTCTTTGAGGAAGTTACCACCATCTCTGA TATAGACACACTTTTTGAGTTGCAGTTTCTGTTAGAATTTTTTGGAGACTAACTTGCCAATTCTGTGAATGTTATTGAATATTTAAAAAG CTGGGTCTGTAATGGGAGGCATTTTATTAGCTGTTGTGATTGGGTAACATGTCCCCTTAGATTTCCTGATTTAAAATTATACAAAATTAC TATTTTTGATAAAATAAAGGAACACCTACAGAAAATTAAGTTTCTAAGATGTTTCTATACTTCATTAGAAAAGATTTTATTACTATTACT TATGGTTATTGGTGATTAACACTTAATGCGTCTCCTCTGATTTTGTGTTCCATGAGGTGCTTGGAACATTTGGAGTGCTCTGTGCGAGGG ACATACAGTGATATAGGAAATTTAAAAATTAAAATAATACCCAAAACCCACTTTATCAGATATGGTATTGTGATGGTTAATATTATGTGT CAACTTGGTGAGGCTATGGCGCCCATGTGTTTGGTCAAACACTAGCCTAGATGTTGCTGTGAATATATTTTGTAGATGTGATTAACATTT >32304_32304_2_GALNT7-GAB1_GALNT7_chr4_174090112_ENST00000265000_GAB1_chr4_144336630_ENST00000262995_length(amino acids)=742AA_BP=20 MRLKIGFILRSLLVVGSFLGLVVLWSSLTPRPDDPSPLSRMRAWKRRWFVLRSGRLTGDPDVLEYYKNDHAKKPIRIIDLNLCQQVDAGL TFNKKEFENSYIFDINTIDRIFYLVADSEEEMNKWVRCICDICGFNPTEEDPVKPPGSSLQAPADLPLAINTAPPSTQADSSSATLPPPY QLINVPPHLETLGIQEDPQDYLLLINCQSKKPEPTRTHADSAKSTSSETDCNDNVPSHKNPASSQSKHGMNGFFQQQMIYDSPPSRAPSA SVDSSLYNLPRSYSHDVLPKVSPSSTEADGELYVFNTPSGTSSVETQMRHVSISYDIPPTPGNTYQIPRTFPEGTLGQTSKLDTIPDIPP PRPPKPHPAHDRSPVETCSIPRTASDTDSSYCIPTAGMSPSRSNTISTVDLNKLRKDASSQDCYDIPRAFPSDRSSSLEGFHNHFKVKNV LTVGSVSSEELDENYVPMNPNSPPRQHSSSFTEPIQEANYVPMTPGTFDFSSFGMQVPPPAHMGFRSSPKTPPRRPVPVADCEPPPVDRN LKPDRKGQSPKILRLKPHGLERTDSQTIGDFATRRKVKPAPLEIKPLPEWEELQAPVRSPITRSFARDSSRFPMSPRPDSVHSTTSSSDS HDSEENYVPMNPNLSSEDPNLFGSNSLDGGSSPMIKPKGDKQVEYLDLDLDSGKSTPPRKQKSSGSGSSVADERVDYVVVDQQKTLALKS -------------------------------------------------------------- >32304_32304_3_GALNT7-GAB1_GALNT7_chr4_174090112_ENST00000512285_GAB1_chr4_144336630_ENST00000262994_length(transcript)=2425nt_BP=151nt GTGAGTCTCTCGCCGCCGGAGGAAGATGAGGCTGAAGATTGGGTTCATCTTACGCAGTTTGCTGGTGGTGGGAAGCTTCCTGGGGCTAGT GGTCCTCTGGTCTTCCCTGACCCCGCGGCCGGACGACCCAAGCCCGCTGAGCAGGATGAGGGCATGGAAGAGGAGATGGTTCGTGTTACG CAGTGGCCGTTTAACTGGAGATCCAGATGTTTTGGAATATTACAAAAATGATCATGCCAAGAAGCCTATTCGTATTATTGATTTAAATTT ATGTCAACAAGTAGATGCTGGATTGACATTTAACAAAAAAGAGTTTGAAAACAGCTACATTTTTGATATCAACACTATTGACCGGATTTT CTACTTGGTAGCAGACAGCGAGGAGGAGATGAATAAGTGGGTTCGTTGTATTTGTGACATCTGTGGGTTTAATCCAACAGAAGAAGATCC TGTGAAGCCACCTGGCAGCTCTTTACAAGCACCAGCTGATTTACCTTTAGCTATAAATACAGCACCACCATCCACCCAGGCAGATTCATC CTCTGCTACTCTACCTCCTCCATATCAGCTAATCAATGTTCCACCACACCTGGAAACTCTTGGCATTCAGGAGGATCCTCAAGACTACCT GTTGCTCATCAACTGTCAAAGCAAGAAGCCCGAACCCACCAGAACGCATGCTGATTCTGCAAAATCCACCTCTTCTGAAACAGACTGCAA TGATAACGTCCCTTCTCATAAAAATCCTGCTTCCTCCCAGAGCAAACATGGAATGAATGGCTTTTTTCAGCAGCAAATGATATACGACTC TCCACCTTCACGTGCCCCATCTGCTTCAGTTGACTCCAGCCTTTATAACCTGCCCAGGAGTTATTCCCATGATGTTTTACCAAAGGTGTC TCCATCAAGTACTGAAGCAGATGGAGAACTCTATGTTTTTAATACCCCATCTGGGACATCGAGTGTAGAGACTCAAATGAGGCATGTATC TATTAGTTATGACATTCCTCCAACACCTGGTAATACTTATCAGATTCCACGAACATTTCCAGAAGGAACCTTGGGACAGACATCAAAGCT AGACACTATTCCAGATATTCCTCCACCTCGGCCACCGAAACCACATCCAGCTCATGACCGATCTCCTGTGGAAACGTGTAGTATCCCACG CACCGCCTCAGACACTGACAGTAGTTACTGTATCCCTACAGCAGGGATGTCGCCTTCACGTAGTAATACCATTTCCACTGTGGATTTAAA CAAATTGCGAAAAGATGCTAGTTCTCAAGACTGCTATGATATTCCACGAGCATTTCCAAGTGATAGATCTAGTTCACTTGAAGGCTTCCA TAACCACTTTAAAGTCAAAAATGTGTTGACAGTGGGAAGTGTTTCAAGTGAAGAACTGGATGAAAATTACGTCCCAATGAATCCCAATTC ACCACCACGACAACATTCCAGCAGTTTTACAGAACCAATTCAGGAAGCAAATTATGTGCCAATGACTCCAGGAACATTTGATTTTTCCTC ATTTGGAATGCAAGTTCCTCCTCCTGCTCATATGGGCTTCAGGTCCAGCCCAAAAACCCCTCCCAGAAGGCCAGTTCCTGTTGCAGACTG TGAACCACCCCCCGTGGATAGGAACCTCAAGCCAGACAGAAAAGTCAAGCCAGCGCCTTTAGAAATAAAACCTTTGCCAGAATGGGAAGA ATTACAAGCCCCAGTTAGATCTCCCATCACTAGGAGTTTTGCTCGAGACTCTTCCAGGTTTCCCATGTCCCCCCGACCAGATTCAGTGCA TAGCACAACTTCAAGCAGTGACTCACACGACAGTGAAGAGAATTATGTTCCCATGAACCCAAACCTGTCCAGTGAAGACCCAAATCTCTT TGGCAGTAACAGTCTTGATGGAGGAAGCAGCCCTATGATCAAGCCCAAAGGAGACAAACAGGTGGAATACTTAGATCTCGACTTAGATTC TGGGAAATCCACACCACCACGTAAGCAAAAGAGCAGTGGCTCAGGCAGCAGTGTAGCAGATGAGAGAGTGGATTATGTTGTTGTTGACCA ACAGAAGACCTTGGCTCTAAAGAGTACCCGGGAAGCCTGGACAGATGGGAGACAGTCCACAGAATCAGAAACGCCAGCGAAGAGTGTGAA ATGAAAATATTGCCTTGCCATTTCTGAACAAAAGAAAACTGAATTGTAAAGATAAATCCCTTTTGAAGAATGACTTGACACTTCCACTCT AGGTAGATCCTCAAATGAGTAGAGTTGAAGTCAAAGGACCTTTCTGACATAATCAAGCAATTTAGACTTAAGTGGTGCTTTGTGGTATCT >32304_32304_3_GALNT7-GAB1_GALNT7_chr4_174090112_ENST00000512285_GAB1_chr4_144336630_ENST00000262994_length(amino acids)=712AA_BP=20 MRLKIGFILRSLLVVGSFLGLVVLWSSLTPRPDDPSPLSRMRAWKRRWFVLRSGRLTGDPDVLEYYKNDHAKKPIRIIDLNLCQQVDAGL TFNKKEFENSYIFDINTIDRIFYLVADSEEEMNKWVRCICDICGFNPTEEDPVKPPGSSLQAPADLPLAINTAPPSTQADSSSATLPPPY QLINVPPHLETLGIQEDPQDYLLLINCQSKKPEPTRTHADSAKSTSSETDCNDNVPSHKNPASSQSKHGMNGFFQQQMIYDSPPSRAPSA SVDSSLYNLPRSYSHDVLPKVSPSSTEADGELYVFNTPSGTSSVETQMRHVSISYDIPPTPGNTYQIPRTFPEGTLGQTSKLDTIPDIPP PRPPKPHPAHDRSPVETCSIPRTASDTDSSYCIPTAGMSPSRSNTISTVDLNKLRKDASSQDCYDIPRAFPSDRSSSLEGFHNHFKVKNV LTVGSVSSEELDENYVPMNPNSPPRQHSSSFTEPIQEANYVPMTPGTFDFSSFGMQVPPPAHMGFRSSPKTPPRRPVPVADCEPPPVDRN LKPDRKVKPAPLEIKPLPEWEELQAPVRSPITRSFARDSSRFPMSPRPDSVHSTTSSSDSHDSEENYVPMNPNLSSEDPNLFGSNSLDGG -------------------------------------------------------------- >32304_32304_4_GALNT7-GAB1_GALNT7_chr4_174090112_ENST00000512285_GAB1_chr4_144336630_ENST00000262995_length(transcript)=7633nt_BP=151nt GTGAGTCTCTCGCCGCCGGAGGAAGATGAGGCTGAAGATTGGGTTCATCTTACGCAGTTTGCTGGTGGTGGGAAGCTTCCTGGGGCTAGT GGTCCTCTGGTCTTCCCTGACCCCGCGGCCGGACGACCCAAGCCCGCTGAGCAGGATGAGGGCATGGAAGAGGAGATGGTTCGTGTTACG CAGTGGCCGTTTAACTGGAGATCCAGATGTTTTGGAATATTACAAAAATGATCATGCCAAGAAGCCTATTCGTATTATTGATTTAAATTT ATGTCAACAAGTAGATGCTGGATTGACATTTAACAAAAAAGAGTTTGAAAACAGCTACATTTTTGATATCAACACTATTGACCGGATTTT CTACTTGGTAGCAGACAGCGAGGAGGAGATGAATAAGTGGGTTCGTTGTATTTGTGACATCTGTGGGTTTAATCCAACAGAAGAAGATCC TGTGAAGCCACCTGGCAGCTCTTTACAAGCACCAGCTGATTTACCTTTAGCTATAAATACAGCACCACCATCCACCCAGGCAGATTCATC CTCTGCTACTCTACCTCCTCCATATCAGCTAATCAATGTTCCACCACACCTGGAAACTCTTGGCATTCAGGAGGATCCTCAAGACTACCT GTTGCTCATCAACTGTCAAAGCAAGAAGCCCGAACCCACCAGAACGCATGCTGATTCTGCAAAATCCACCTCTTCTGAAACAGACTGCAA TGATAACGTCCCTTCTCATAAAAATCCTGCTTCCTCCCAGAGCAAACATGGAATGAATGGCTTTTTTCAGCAGCAAATGATATACGACTC TCCACCTTCACGTGCCCCATCTGCTTCAGTTGACTCCAGCCTTTATAACCTGCCCAGGAGTTATTCCCATGATGTTTTACCAAAGGTGTC TCCATCAAGTACTGAAGCAGATGGAGAACTCTATGTTTTTAATACCCCATCTGGGACATCGAGTGTAGAGACTCAAATGAGGCATGTATC TATTAGTTATGACATTCCTCCAACACCTGGTAATACTTATCAGATTCCACGAACATTTCCAGAAGGAACCTTGGGACAGACATCAAAGCT AGACACTATTCCAGATATTCCTCCACCTCGGCCACCGAAACCACATCCAGCTCATGACCGATCTCCTGTGGAAACGTGTAGTATCCCACG CACCGCCTCAGACACTGACAGTAGTTACTGTATCCCTACAGCAGGGATGTCGCCTTCACGTAGTAATACCATTTCCACTGTGGATTTAAA CAAATTGCGAAAAGATGCTAGTTCTCAAGACTGCTATGATATTCCACGAGCATTTCCAAGTGATAGATCTAGTTCACTTGAAGGCTTCCA TAACCACTTTAAAGTCAAAAATGTGTTGACAGTGGGAAGTGTTTCAAGTGAAGAACTGGATGAAAATTACGTCCCAATGAATCCCAATTC ACCACCACGACAACATTCCAGCAGTTTTACAGAACCAATTCAGGAAGCAAATTATGTGCCAATGACTCCAGGAACATTTGATTTTTCCTC ATTTGGAATGCAAGTTCCTCCTCCTGCTCATATGGGCTTCAGGTCCAGCCCAAAAACCCCTCCCAGAAGGCCAGTTCCTGTTGCAGACTG TGAACCACCCCCCGTGGATAGGAACCTCAAGCCAGACAGAAAAGGTCAAAGTCCTAAAATTTTAAGACTCAAACCCCATGGTTTAGAGCG AACTGATTCACAAACCATAGGTGACTTTGCTACAAGAAGAAAGGTCAAGCCAGCGCCTTTAGAAATAAAACCTTTGCCAGAATGGGAAGA ATTACAAGCCCCAGTTAGATCTCCCATCACTAGGAGTTTTGCTCGAGACTCTTCCAGGTTTCCCATGTCCCCCCGACCAGATTCAGTGCA TAGCACAACTTCAAGCAGTGACTCACACGACAGTGAAGAGAATTATGTTCCCATGAACCCAAACCTGTCCAGTGAAGACCCAAATCTCTT TGGCAGTAACAGTCTTGATGGAGGAAGCAGCCCTATGATCAAGCCCAAAGGAGACAAACAGGTGGAATACTTAGATCTCGACTTAGATTC TGGGAAATCCACACCACCACGTAAGCAAAAGAGCAGTGGCTCAGGCAGCAGTGTAGCAGATGAGAGAGTGGATTATGTTGTTGTTGACCA ACAGAAGACCTTGGCTCTAAAGAGTACCCGGGAAGCCTGGACAGATGGGAGACAGTCCACAGAATCAGAAACGCCAGCGAAGAGTGTGAA ATGAAAATATTGCCTTGCCATTTCTGAACAAAAGAAAACTGAATTGTAAAGATAAATCCCTTTTGAAGAATGACTTGACACTTCCACTCT AGGTAGATCCTCAAATGAGTAGAGTTGAAGTCAAAGGACCTTTCTGACATAATCAAGCAATTTAGACTTAAGTGGTGCTTTGTGGTATCT GAACAATTCATAACATGTAAATAATGTGGGAAAATAGTATTGTTTAGCTCCCAGAGAAACATTTGTTCCACAGTTAACACACTCGTAGTA TTACTGTATTTATGCACTTTTTCATCTAAAACATTGTTCTGGGTTTTCCCAATGTACCTTACCATAATTCCTTTGGGAGTTCTTGTTTTT TGTCACACTACTTTATATAACAATACTAAGTCAACTAAGCTACTTTTAGATTTGGAAATTGCTGTTTACAGTCTAACAACATTAAAATGA GAGGTAGATTCACAAGTTAGCTTTCTACCTGAAGCTTCAGGTGATAACCATTAGCTTATACTTGGACTCATCATTTGTTGCCTTCCAAAA TGCTGAGGATAATGTATGTACTGGTGTCAGGACCTAGTTCTCTGGTTAATGTACATTTAGTTTTTAATGGTGGAACTTTGTTATATTTTG TTAATTACAGTGTTTTTGGTTCATTGAGTGAAGATTCTGCCGGGTGGGATCTTGCACCTTTGAAAGACTGAATAATTACACTACCAAGTA AGCCTGCAAATCATTGATGGCATGCAGTGATGATGTGCTCTTACACTTGTTAACATGTATTAAGTGTTATTTGCAAAAGGTAGATTATGT AACCAATCAGGTACGTACCAGGCAGTGATGTGCTAATACACTGATCAGGTTTAGACAATGAGCTTTGGTTGTGTTCTTGTTAGTCCTAAT ATTGGTTTTCAGTTTGGAATTAATAAAGCAGTTGACATTCACTGTTAGTTACAGCAACATACTGTGATTTTTAATTAGATAGTAATTCAG ATTTATTACTCTATGAAATTCTGTCTTTTGACACCATAGTGCCCTTTCTATGATTTTTTTTACTTAATATTCTTCTTGGCCTTATATTTA ATTCCCTATGCAATTAATATTTTATATCTGCATTTTTTTAAAAAAAATAGATGTTATATAAGTGATTCTCGTATGTAGCACCTGTTGCTT TTCCACTGAAAGAATTACGGATTTTGTACTGTGATTTATATTCACTGCCCCAATTCAAGAAATATTGGAGCCTTGCTACAATGTGAAATG TTATAGTCATGGACTCCTTCCAACCAGATTTCTGAAAACACCAGAGGGATGGTATAATTCTGTCTCACCTATAACATGGTCCTGTGACAT AGATATTAAGACCACAAGTTGTAGTGAGGCTACAATTATATTCGTCTGTCTTGGCTTTGCAACATAATTTAGAAAGCACGTATAGTTGTT TTTTAACCAAGTTACATACAATCTCATGTACTGATTTGAGACTTATAACAATTTTTGGAGGGGGCATAGAGAAAGGAGTGCCCACAGTTG AGGCATGACCCCCTCCATTCAGACCTCTAACTGTTGCCTGAGTACACAGATGTGCCCTGATTTCTGGCCCATTGGCCATAGTACTGTGCC TAATCAATGTAATAGGTTTATTTTCCCAATCCTCAAACTAAAAATGTTCATAACAAGATGAATTGTAGACTAGTAACATTTGATGCTTTT AAATATTTGCTTCTTTTTAAACAAAAACTAAAACCCAGAAGTGAATTTTTAGGTGGATTTTTAAATAAAAAAGATTGATTGAGTTTGGTG TGCAAGCTGTTTTATAATGAAACAACAAAATGAAATCTAAAATCCTGAAATGTGCCTAAACTATCAAAACACACGATACAGCTAATGTGT AAAGATGCTAAATTCTGTTACTTGGAGGATGAATATATTTAAGATTTAAAACACAATAATAAATACATGATTAATTCAAAAATAAAAATC TTTACAGCTGCCTATCAAGGGTCTAAAGCACTTAATGAATGTTTTTAGTCTAACTTATCATTAACTTTTTACAAGTCACCATATTTGAAG ATCTGTAGCACTCTGATTTTCAGAAAATTTTTCATTCTGAATAATTTAAAAATGGTGATGTATTAGAAAGGCAGTTTGCTTTAGAAAACT AAATCACATTGAACATTGTATTAGAGAATTAAATTAAAAGTTTCTTACAGAGCAGTATTTTCCAAACATTTTTAGCACTAGAATCTTTTT AGATGAAATTTTATGTATAACCCCAATACATAAAGCCTGAAAACTCAATTTTATCAATATAAATGTATTTTGGGTTCACATTTATGCTTA TTCATTTTGGCTCATTACTAAGCATAATAAGATTCTGAGTTATTTCTGAATAACACAAATGTGGAGTTATACATAGTTGATGAAACCAGC AGCCAATTTATAGCTATGCCCTGTTTTATTTGTATACTATCAAGAAAATTTTGATTCACACAAATGTAAGCAAAAATAATAGGTTTTAAA CATACATCTCAGGAAATTCTTTAATTAGAGATAGCTAAAGTTATTCAAGGTCTATACAAAAATAAGTTATCCTGGTAGTGGAAGTTAATA CATAAGCAGTCTCCAGTGTGGTAAAGTAGGGTATGTAACACATCAGAATGTGCGTTTTTATTAGGTTTTAAAATATGCACGTATAAAAAC TAAATTTGAATCAAACCCTTTTAACTCACCTCCAAGAAGCTAGACTTTGGCCAGGAATGGGCTAAAAACCACTGGTTAACGATGTGACAG TTATGATCTTGGAGATTGGAAATCTTTCTTCCACATTAGAGTTCTTTACCTTAATTCCTTATTCTGAAAAATTGTAAGATTTTATGAAGG TTTGAATACTGAAGCACAGTTCTGCTTTCAAAAATTAAAATTCAAACTTGAAAAAGCTGTTTAACCCATGGAAGATATCATTTAGTAAGA TGTAAAAGATTTTTTAAATCTACACTTCAGTTTATACATCTTTATCATTATCAATACTATATAAGTTACTGTGAGCATTTTAGAGAATTC CATAAAGGTACTATGAGTGTGTCTGTATGTGTGTGTATATATAGCATTGTATTTAATCATAGACTAAATTTAATTTGATATAGAAATACT ACTTTACTTGTACATTAAGGTCATAATTTCTGCTGGACTCTTTTATATTTAATTAATGGGGATTATAGTCTTCCTTCATAAATGCATTTA AACCTGAAATTGAACACCAGTGTTTTTCTTTTTCTACTTATGGGAAGTTGTCTGCTTCCCCCTTTAGAGAAAACAGTATTTTTATATTTT GTTAAAATATTAACTACTTTATGCCTACACACTATGCTGTAGATACTGATCATAATTCTTGGGTGTTCACAAACACTCCTAGTGCCTCTT TTTTGGCCCGTTGAAAGTGTTGGTATTACTACTTTCACTACAGAGCCTTTGGCCCTCTAATAATGCTGAGGTGGGCTGATCCTTCCCATT TCTGTCTTCGGGTCATTCTGGTAGGTCTTCTCCTCCACTGTCAAGTAAGCAATCAGGTCCGTGACAGGGATTGGACATATGAACAAATTA AGTGGATACACACAGTGAGAAAGATACATGCATTCTATGGTAACAACTACTGTCAATAACATCTGATGTTACATGCACATTTATATATAT ATAATTTTAAAAACTGAACTATGAGAAGCCATGGTATAAATGAATATTGTGGACATCATGGACTTGATATGATAGAAATCAATTGTCAGC TTGAGAAAGTTGTTTTTAATCTGTCTAAATAGTTCATGCATTACTACAGTTAAAAATAGTTTCATTTGTCTTCTATAGACTTAATTTTAT TCCGGTTCAGTATAATCTCTGTTAACAGAGTTTCAGCAAACTGATTGGTCAAGGTATTAACATAGCTTCTACTTCCTTTACTTAAAAAGA TGTGGTTTTATGTAAGTTCTTGATTACTGATGATCATCCCAAATTTTGACAACAAAATCATATGTATAAATTTATTTCTCCCCTCTTGTT CATCATCTTTTGTAAAGGTCCCATTGTAGATCTTTTCTGCTACCAAATAAAACTTTTCAAACAATTTGGTTTCAAGACCTTAAATAGACA AGTTGGATACTAAGATTGTGAACTGATAAGGACATATAAATTTATATTTCCAGCCCTTCCTTAGAGTCTTTATCTGCATCAAAAACCCAA TTCTGCCATTAACTGTGCTTCCCAGTCCCACCTCTATATGTCACTCATTTTCTGCAACAAAGATCTCACTAAATCATGTTGAAACACAAG TCATGATCCTCTCTAAGTAAATAGAAAAAGCTCCCTGGAAAAACTCTGTTGCCACATGCACGTGCCCTGTTACTCCTCCAGCCAGCCAGT GCTGCCAGCATTTTATTGTGTAAAAGTCCAAATAAATAAGGGCCTGCATGCAACCTTTATCTTCAGAAACTAGGTTTTATATGTAAAATG TGACTTGGGAAATGATTCTGTTTATTAACTGGCTGGGATTTTTCATTTCTATGAAAGTTTCAAACATCTCCAGTACTTTATAAAATCCCA ACAATTGCTGTAAGTCAGCACTTTGGTCCACTCAGCCCACCCAGCCCACTTGCAACTCTGACTCTTCACTGAATCATATTTGGGAAGTTT GGGTAGGGTGAGGCTATCTTCTTCAAGATTATTTTCTCATATGTCTGTCTGTCACCTTGTAAACCATGAGACTCCTGGGTATTTGCATGT AACTTCTTTGAGGAAGTTACCACCATCTCTGATATAGACACACTTTTTGAGTTGCAGTTTCTGTTAGAATTTTTTGGAGACTAACTTGCC AATTCTGTGAATGTTATTGAATATTTAAAAAGCTGGGTCTGTAATGGGAGGCATTTTATTAGCTGTTGTGATTGGGTAACATGTCCCCTT AGATTTCCTGATTTAAAATTATACAAAATTACTATTTTTGATAAAATAAAGGAACACCTACAGAAAATTAAGTTTCTAAGATGTTTCTAT ACTTCATTAGAAAAGATTTTATTACTATTACTTATGGTTATTGGTGATTAACACTTAATGCGTCTCCTCTGATTTTGTGTTCCATGAGGT GCTTGGAACATTTGGAGTGCTCTGTGCGAGGGACATACAGTGATATAGGAAATTTAAAAATTAAAATAATACCCAAAACCCACTTTATCA GATATGGTATTGTGATGGTTAATATTATGTGTCAACTTGGTGAGGCTATGGCGCCCATGTGTTTGGTCAAACACTAGCCTAGATGTTGCT >32304_32304_4_GALNT7-GAB1_GALNT7_chr4_174090112_ENST00000512285_GAB1_chr4_144336630_ENST00000262995_length(amino acids)=742AA_BP=20 MRLKIGFILRSLLVVGSFLGLVVLWSSLTPRPDDPSPLSRMRAWKRRWFVLRSGRLTGDPDVLEYYKNDHAKKPIRIIDLNLCQQVDAGL TFNKKEFENSYIFDINTIDRIFYLVADSEEEMNKWVRCICDICGFNPTEEDPVKPPGSSLQAPADLPLAINTAPPSTQADSSSATLPPPY QLINVPPHLETLGIQEDPQDYLLLINCQSKKPEPTRTHADSAKSTSSETDCNDNVPSHKNPASSQSKHGMNGFFQQQMIYDSPPSRAPSA SVDSSLYNLPRSYSHDVLPKVSPSSTEADGELYVFNTPSGTSSVETQMRHVSISYDIPPTPGNTYQIPRTFPEGTLGQTSKLDTIPDIPP PRPPKPHPAHDRSPVETCSIPRTASDTDSSYCIPTAGMSPSRSNTISTVDLNKLRKDASSQDCYDIPRAFPSDRSSSLEGFHNHFKVKNV LTVGSVSSEELDENYVPMNPNSPPRQHSSSFTEPIQEANYVPMTPGTFDFSSFGMQVPPPAHMGFRSSPKTPPRRPVPVADCEPPPVDRN LKPDRKGQSPKILRLKPHGLERTDSQTIGDFATRRKVKPAPLEIKPLPEWEELQAPVRSPITRSFARDSSRFPMSPRPDSVHSTTSSSDS HDSEENYVPMNPNLSSEDPNLFGSNSLDGGSSPMIKPKGDKQVEYLDLDLDSGKSTPPRKQKSSGSGSSVADERVDYVVVDQQKTLALKS -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for GALNT7-GAB1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for GALNT7-GAB1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for GALNT7-GAB1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | C0032460 | Polycystic Ovary Syndrome | 1 | CTD_human | |
| Tgene | C1136382 | Sclerocystic Ovaries | 1 | CTD_human | |
| Tgene | C1854275 | DEAFNESS, AUTOSOMAL RECESSIVE 26 | 1 | CTD_human;UNIPROT |
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