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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
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Fusion gene:ADAM22-RUNDC3B (FusionGDB2 ID:HG53616TG154661)

Fusion Gene Summary for ADAM22-RUNDC3B

Fusion gene summary

Fusion gene information	Fusion gene name: ADAM22-RUNDC3B
	Fusion gene ID: hg53616tg154661
		Hgene	Tgene
	Gene symbol	ADAM22	RUNDC3B
	Gene ID	53616	154661
	Gene name	ADAM metallopeptidase domain 22	RUN domain containing 3B
	Synonyms	ADAM 22\|EIEE61\|MDC2	RPIB9\|RPIP9
	Cytomap	('ADAM22')('RUNDC3B') 7q21.12	7q21.12
	Type of gene	protein-coding	protein-coding
	Description	disintegrin and metalloproteinase domain-containing protein 22a disintegrin and metalloproteinase domain 22metalloproteinase-disintegrin ADAM22-3metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2	RUN domain-containing protein 3BRPIP-9Rap2 binding protein 9Rap2-interacting protein 9rap2-binding protein 9
	Modification date	20200313	20200320
	UniProtAcc	.	.
	Ensembl transtripts involved in fusion gene	ENST00000265727, ENST00000315984, ENST00000398201, ENST00000398204, ENST00000398209, ENST00000439864, ENST00000476330,
Fusion gene scores	* DoF score	3 X 3 X 3=27	6 X 6 X 4=144
	# samples	3	6
	** MAII score	log2(3/27*10)=0.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0	log2(6/144*10)=-1.26303440583379 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: ADAM22 [Title/Abstract] AND RUNDC3B [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	ADAM22(87607727)-RUNDC3B(87445456), # samples:2
Anticipated loss of major functional domain due to fusion event.	ADAM22-RUNDC3B seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. ADAM22-RUNDC3B seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

Fusion gene breakpoints across ADAM22 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across RUNDC3B (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	UCEC	TCGA-AJ-A3QS-01A	ADAM22	chr7	87607727	-	RUNDC3B	chr7	87445456	+
ChimerDB4	UCEC	TCGA-AJ-A3QS-01A	ADAM22	chr7	87607727	+	RUNDC3B	chr7	87445456	+

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Fusion Gene ORF analysis for ADAM22-RUNDC3B

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-intron	ENST00000265727	ENST00000496000	ADAM22	chr7	87607727	+	RUNDC3B	chr7	87445456	+
5CDS-intron	ENST00000315984	ENST00000496000	ADAM22	chr7	87607727	+	RUNDC3B	chr7	87445456	+
5CDS-intron	ENST00000398201	ENST00000496000	ADAM22	chr7	87607727	+	RUNDC3B	chr7	87445456	+
5CDS-intron	ENST00000398204	ENST00000496000	ADAM22	chr7	87607727	+	RUNDC3B	chr7	87445456	+
5CDS-intron	ENST00000398209	ENST00000496000	ADAM22	chr7	87607727	+	RUNDC3B	chr7	87445456	+
5CDS-intron	ENST00000439864	ENST00000496000	ADAM22	chr7	87607727	+	RUNDC3B	chr7	87445456	+
In-frame	ENST00000265727	ENST00000338056	ADAM22	chr7	87607727	+	RUNDC3B	chr7	87445456	+
In-frame	ENST00000265727	ENST00000394654	ADAM22	chr7	87607727	+	RUNDC3B	chr7	87445456	+
In-frame	ENST00000265727	ENST00000493037	ADAM22	chr7	87607727	+	RUNDC3B	chr7	87445456	+
In-frame	ENST00000315984	ENST00000338056	ADAM22	chr7	87607727	+	RUNDC3B	chr7	87445456	+
In-frame	ENST00000315984	ENST00000394654	ADAM22	chr7	87607727	+	RUNDC3B	chr7	87445456	+
In-frame	ENST00000315984	ENST00000493037	ADAM22	chr7	87607727	+	RUNDC3B	chr7	87445456	+
In-frame	ENST00000398201	ENST00000338056	ADAM22	chr7	87607727	+	RUNDC3B	chr7	87445456	+
In-frame	ENST00000398201	ENST00000394654	ADAM22	chr7	87607727	+	RUNDC3B	chr7	87445456	+
In-frame	ENST00000398201	ENST00000493037	ADAM22	chr7	87607727	+	RUNDC3B	chr7	87445456	+
In-frame	ENST00000398204	ENST00000338056	ADAM22	chr7	87607727	+	RUNDC3B	chr7	87445456	+
In-frame	ENST00000398204	ENST00000394654	ADAM22	chr7	87607727	+	RUNDC3B	chr7	87445456	+
In-frame	ENST00000398204	ENST00000493037	ADAM22	chr7	87607727	+	RUNDC3B	chr7	87445456	+
In-frame	ENST00000398209	ENST00000338056	ADAM22	chr7	87607727	+	RUNDC3B	chr7	87445456	+
In-frame	ENST00000398209	ENST00000394654	ADAM22	chr7	87607727	+	RUNDC3B	chr7	87445456	+
In-frame	ENST00000398209	ENST00000493037	ADAM22	chr7	87607727	+	RUNDC3B	chr7	87445456	+
In-frame	ENST00000439864	ENST00000338056	ADAM22	chr7	87607727	+	RUNDC3B	chr7	87445456	+
In-frame	ENST00000439864	ENST00000394654	ADAM22	chr7	87607727	+	RUNDC3B	chr7	87445456	+
In-frame	ENST00000439864	ENST00000493037	ADAM22	chr7	87607727	+	RUNDC3B	chr7	87445456	+
intron-3CDS	ENST00000476330	ENST00000338056	ADAM22	chr7	87607727	+	RUNDC3B	chr7	87445456	+
intron-3CDS	ENST00000476330	ENST00000394654	ADAM22	chr7	87607727	+	RUNDC3B	chr7	87445456	+
intron-3CDS	ENST00000476330	ENST00000493037	ADAM22	chr7	87607727	+	RUNDC3B	chr7	87445456	+
intron-intron	ENST00000476330	ENST00000496000	ADAM22	chr7	87607727	+	RUNDC3B	chr7	87445456	+

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000398204	ADAM22	chr7	87607727	+	ENST00000338056	RUNDC3B	chr7	87445456	+	3180	646	323	913	196
ENST00000398204	ADAM22	chr7	87607727	+	ENST00000493037	RUNDC3B	chr7	87445456	+	1340	646	323	913	196
ENST00000398204	ADAM22	chr7	87607727	+	ENST00000394654	RUNDC3B	chr7	87445456	+	1398	646	323	913	196
ENST00000439864	ADAM22	chr7	87607727	+	ENST00000338056	RUNDC3B	chr7	87445456	+	3072	538	215	805	196
ENST00000439864	ADAM22	chr7	87607727	+	ENST00000493037	RUNDC3B	chr7	87445456	+	1232	538	215	805	196
ENST00000439864	ADAM22	chr7	87607727	+	ENST00000394654	RUNDC3B	chr7	87445456	+	1290	538	215	805	196
ENST00000398201	ADAM22	chr7	87607727	+	ENST00000338056	RUNDC3B	chr7	87445456	+	2976	442	119	709	196
ENST00000398201	ADAM22	chr7	87607727	+	ENST00000493037	RUNDC3B	chr7	87445456	+	1136	442	119	709	196
ENST00000398201	ADAM22	chr7	87607727	+	ENST00000394654	RUNDC3B	chr7	87445456	+	1194	442	119	709	196
ENST00000265727	ADAM22	chr7	87607727	+	ENST00000338056	RUNDC3B	chr7	87445456	+	2936	402	79	669	196
ENST00000265727	ADAM22	chr7	87607727	+	ENST00000493037	RUNDC3B	chr7	87445456	+	1096	402	79	669	196
ENST00000265727	ADAM22	chr7	87607727	+	ENST00000394654	RUNDC3B	chr7	87445456	+	1154	402	79	669	196
ENST00000315984	ADAM22	chr7	87607727	+	ENST00000338056	RUNDC3B	chr7	87445456	+	2936	402	79	669	196
ENST00000315984	ADAM22	chr7	87607727	+	ENST00000493037	RUNDC3B	chr7	87445456	+	1096	402	79	669	196
ENST00000315984	ADAM22	chr7	87607727	+	ENST00000394654	RUNDC3B	chr7	87445456	+	1154	402	79	669	196
ENST00000398209	ADAM22	chr7	87607727	+	ENST00000338056	RUNDC3B	chr7	87445456	+	2903	369	46	636	196
ENST00000398209	ADAM22	chr7	87607727	+	ENST00000493037	RUNDC3B	chr7	87445456	+	1063	369	46	636	196
ENST00000398209	ADAM22	chr7	87607727	+	ENST00000394654	RUNDC3B	chr7	87445456	+	1121	369	46	636	196

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000398204	ENST00000338056	ADAM22	chr7	87607727	+	RUNDC3B	chr7	87445456	+	0.000253044	0.999747
ENST00000398204	ENST00000493037	ADAM22	chr7	87607727	+	RUNDC3B	chr7	87445456	+	0.001772832	0.9982272
ENST00000398204	ENST00000394654	ADAM22	chr7	87607727	+	RUNDC3B	chr7	87445456	+	0.001451234	0.9985487
ENST00000439864	ENST00000338056	ADAM22	chr7	87607727	+	RUNDC3B	chr7	87445456	+	0.000217384	0.9997826
ENST00000439864	ENST00000493037	ADAM22	chr7	87607727	+	RUNDC3B	chr7	87445456	+	0.000891526	0.9991085
ENST00000439864	ENST00000394654	ADAM22	chr7	87607727	+	RUNDC3B	chr7	87445456	+	0.000770495	0.99922955
ENST00000398201	ENST00000338056	ADAM22	chr7	87607727	+	RUNDC3B	chr7	87445456	+	0.000250308	0.9997497
ENST00000398201	ENST00000493037	ADAM22	chr7	87607727	+	RUNDC3B	chr7	87445456	+	0.00078583	0.9992142
ENST00000398201	ENST00000394654	ADAM22	chr7	87607727	+	RUNDC3B	chr7	87445456	+	0.000644874	0.99935514
ENST00000265727	ENST00000338056	ADAM22	chr7	87607727	+	RUNDC3B	chr7	87445456	+	0.000197611	0.9998024
ENST00000265727	ENST00000493037	ADAM22	chr7	87607727	+	RUNDC3B	chr7	87445456	+	0.000663473	0.99933654
ENST00000265727	ENST00000394654	ADAM22	chr7	87607727	+	RUNDC3B	chr7	87445456	+	0.000524039	0.999476
ENST00000315984	ENST00000338056	ADAM22	chr7	87607727	+	RUNDC3B	chr7	87445456	+	0.000197611	0.9998024
ENST00000315984	ENST00000493037	ADAM22	chr7	87607727	+	RUNDC3B	chr7	87445456	+	0.000663473	0.99933654
ENST00000315984	ENST00000394654	ADAM22	chr7	87607727	+	RUNDC3B	chr7	87445456	+	0.000524039	0.999476
ENST00000398209	ENST00000338056	ADAM22	chr7	87607727	+	RUNDC3B	chr7	87445456	+	0.000177536	0.99982244
ENST00000398209	ENST00000493037	ADAM22	chr7	87607727	+	RUNDC3B	chr7	87445456	+	0.000580484	0.99941957
ENST00000398209	ENST00000394654	ADAM22	chr7	87607727	+	RUNDC3B	chr7	87445456	+	0.000466066	0.999534

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Fusion Genomic Features for ADAM22-RUNDC3B

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	1-p	p (fusion gene breakpoint)
ADAM22	chr7	87607727	+	RUNDC3B	chr7	87445455	+	0.008982169	0.9910178
ADAM22	chr7	87607727	+	RUNDC3B	chr7	87445455	+	0.008982169	0.9910178

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for ADAM22-RUNDC3B

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr7:87607727/chr7:87445456)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	.
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.	FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Tgene

RUNDC3B

chr7:87607727

chr7:87445456

ENST00000493037

317_342

318

408.0

Coiled coil

Ontology_term=ECO:0000255

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

ADAM22

chr7:87607727

chr7:87445456

ENST00000265727

532_678

107

907.0

Compositional bias

Note=Cys-rich

Hgene

ADAM22

chr7:87607727

chr7:87445456

ENST00000398201

532_678

107

860.0

Compositional bias

Note=Cys-rich

Hgene

ADAM22

chr7:87607727

chr7:87445456

ENST00000398204

532_678

107

871.0

Compositional bias

Note=Cys-rich

Hgene

ADAM22

chr7:87607727

chr7:87445456

ENST00000398209

532_678

107

900.0

Compositional bias

Note=Cys-rich

Hgene

ADAM22

chr7:87607727

chr7:87445456

ENST00000265727

239_438

107

907.0

Domain

Peptidase M12B

Hgene

ADAM22

chr7:87607727

chr7:87445456

ENST00000265727

444_531

107

907.0

Domain

Disintegrin

Hgene

ADAM22

chr7:87607727

chr7:87445456

ENST00000265727

675_712

107

907.0

Domain

Note=EGF-like

Hgene

ADAM22

chr7:87607727

chr7:87445456

ENST00000398201

239_438

107

860.0

Domain

Peptidase M12B

Hgene

ADAM22

chr7:87607727

chr7:87445456

ENST00000398201

444_531

107

860.0

Domain

Disintegrin

Hgene

ADAM22

chr7:87607727

chr7:87445456

ENST00000398201

675_712

107

860.0

Domain

Note=EGF-like

Hgene

ADAM22

chr7:87607727

chr7:87445456

ENST00000398204

239_438

107

871.0

Domain

Peptidase M12B

Hgene

ADAM22

chr7:87607727

chr7:87445456

ENST00000398204

444_531

107

871.0

Domain

Disintegrin

Hgene

ADAM22

chr7:87607727

chr7:87445456

ENST00000398204

675_712

107

871.0

Domain

Note=EGF-like

Hgene

ADAM22

chr7:87607727

chr7:87445456

ENST00000398209

239_438

107

900.0

Domain

Peptidase M12B

Hgene

ADAM22

chr7:87607727

chr7:87445456

ENST00000398209

444_531

107

900.0

Domain

Disintegrin

Hgene

ADAM22

chr7:87607727

chr7:87445456

ENST00000398209

675_712

107

900.0

Domain

Note=EGF-like

Hgene

ADAM22

chr7:87607727

chr7:87445456

ENST00000265727

223_736

107

907.0

Topological domain

Extracellular

Hgene

ADAM22

chr7:87607727

chr7:87445456

ENST00000265727

758_906

107

907.0

Topological domain

Cytoplasmic

Hgene

ADAM22

chr7:87607727

chr7:87445456

ENST00000398201

223_736

107

860.0

Topological domain

Extracellular

Hgene

ADAM22

chr7:87607727

chr7:87445456

ENST00000398201

758_906

107

860.0

Topological domain

Cytoplasmic

Hgene

ADAM22

chr7:87607727

chr7:87445456

ENST00000398204

223_736

107

871.0

Topological domain

Extracellular

Hgene

ADAM22

chr7:87607727

chr7:87445456

ENST00000398204

758_906

107

871.0

Topological domain

Cytoplasmic

Hgene

ADAM22

chr7:87607727

chr7:87445456

ENST00000398209

223_736

107

900.0

Topological domain

Extracellular

Hgene

ADAM22

chr7:87607727

chr7:87445456

ENST00000398209

758_906

107

900.0

Topological domain

Cytoplasmic

Hgene

ADAM22

chr7:87607727

chr7:87445456

ENST00000265727

737_757

107

907.0

Transmembrane

Helical

Hgene

ADAM22

chr7:87607727

chr7:87445456

ENST00000398201

737_757

107

860.0

Transmembrane

Helical

Hgene

ADAM22

chr7:87607727

chr7:87445456

ENST00000398204

737_757

107

871.0

Transmembrane

Helical

Hgene

ADAM22

chr7:87607727

chr7:87445456

ENST00000398209

737_757

107

900.0

Transmembrane

Helical

Tgene

RUNDC3B

chr7:87607727

chr7:87445456

ENST00000338056

317_342

384

474.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

RUNDC3B

chr7:87607727

chr7:87445456

ENST00000394654

317_342

367

457.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

RUNDC3B

chr7:87607727

chr7:87445456

ENST00000338056

14_20

384

474.0

Compositional bias

Note=Poly-Gly

Tgene

RUNDC3B

chr7:87607727

chr7:87445456

ENST00000394654

14_20

367

457.0

Compositional bias

Note=Poly-Gly

Tgene

RUNDC3B

chr7:87607727

chr7:87445456

ENST00000493037

14_20

318

408.0

Compositional bias

Note=Poly-Gly

Tgene

RUNDC3B

chr7:87607727

chr7:87445456

ENST00000338056

57_206

384

474.0

Domain

RUN

Tgene

RUNDC3B

chr7:87607727

chr7:87445456

ENST00000394654

57_206

367

457.0

Domain

RUN

Tgene

RUNDC3B

chr7:87607727

chr7:87445456

ENST00000493037

57_206

318

408.0

Domain

RUN

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Fusion Gene Sequence for ADAM22-RUNDC3B

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>1993_1993_1_ADAM22-RUNDC3B_ADAM22_chr7_87607727_ENST00000265727_RUNDC3B_chr7_87445456_ENST00000338056_length(transcript)=2936nt_BP=402nt
GCGGAGCGAGGGAAACGGACTCGGCGGCGCCGGCATGAGGAGCTGAGCGTCTCGGGCGAGGCGGGCTGACGGCAGCACCATGCAGGCGGC
AGTGGCTGTGTCCGTGCCCTTCTTGCTGCTCTGTGTCCTGGGGACCTGCCCTCCGGCGCGCTGCGGCCAGGCAGGAGACGCCTCATTGAT
GGAGCTAGAGAAGAGGAAGGAAAACCGCTTCGTGGAGCGCCAGAGCATCGTGCCACTGCGCCTCATCTACCGCTCGGGCGGCGAAGACGA
AAGTCGGCACGACGCGCTCGACACGCGGGTGCGGGGCGACCTCGGTGGCCCGCAGTTGACTCATGTTGACCAAGCAAGCTTCCAGGTTGA
TGCCTTTGGAACGTCATTCATTCTCGATGTCGTGCTAAATCAGAAAAGTTATCAAAGTCTTGACCAGTTATCAGCAGAAGTTAGCCTTTC
TCAGACTTCACTAGATCCAGGCCAGTCACAAGAAGGAGATGGAAAACAAGACACATTAAATGTAATGAGTGAAGGTAAGGAAGATACTCC
CTCATTACTTGGCCTCTGTGGATCTCTAACGTCAGTGGCAAGTTACAAGTCTCTAACAAGCTTAAAATCTAATGACTACCTTGCAAGTCC
TACAACAGAGATGACAAGTCCAGGCCTAACTCCATCCTGAAAATTTTTGTGTAAAAGCCAAAACTTTTTATGTTGTAAATGTTTAATTTA
CATGTTTGACTGCTGGGAAGACCTTTGAAATTTTATATTGTTCTGGTACATGTCTGAAATTCTATTGCTTGGAGAGAATCCCCTCCAGAT
AAGAGATTTTGAGTGAAAAACATAATGATCCTGCCATTTTTCATTTTTAAAATTCTTACATTTGTCATTGAGAAAGTTCAAAATGGAATA
GGCTTTAAAAAAAAAAAAACTTTCAAAGATCCGCCAAATCATTCATAGCAAATTGTACATATTGTTCAGCTGATTTTTATATATTTAAAT
ACACCTTAGTGGCCAGAGACTGACTTCAAGGTTTTATTCCAGAGACTCCAGAGACTTAAGCTAAGTATTTTTTCATTCTTTCAGATTTTC
AAAAAAAAAAAAAAAAAAAGTTAATTTCATTTTTTCATTAATGTCTTCCTAAGTTCTATGCTTTAAATGCCTTGTTTTTAATAACGGGAA
AGTTCTCAGCTGCATTTTCACAGTGGCTTATTCAGTTTTTCTTTAATATTTACCATTTGGTATCAATTCAGCATTCCACTTAACATTTTA
TAAATTCCATAGGAACATGCCTGTTTTGGTAGTTACTGACTTAATTTGTTAGTGCCACAAGGAAAATATTTTACAGTATTTTATGCCATT
TAGGCAAAATGAATAAACTGTTTTCCAAGATTTTCTTAAAAGATTATCAATTTAAAAGTATGATCAAGTATGCCTCAAAAACTAGAAACA
TTTCAAAATGTAGAACAAACGTTGAAAAATTGTTTTGCCAGGAAAGAGTTCAAGTTCAGTTAAGGATTTGAGAGGCTTTTAAACAAGGAT
CAGTAGGATAGTTATCATATTTACTTAATATATGTCTGATATTCAGTGCTGGTTCTTTTTCCTGTTTGTGCAACAATGAAGTGTGTCATG
TGTGTTTTATAGCCTCTATCATTAATCACACCAGAGTCTCATTTTAAAACATTTTAATGTTAAAACATCCCCACACTTATACACAGGTAA
AATTAGTTTTTTTTTTTTTAAAGTTGTAATCTGTACTTTTTTTTTTTTGCAATTTTTGAAACAGCTACATTAATCCCTAAAAATCCCACC
ATACTGAAAATGTATGGCGTGTATTTTCTATAGTAAGTAATATGAGGAAAACATGATTAGCTGTGCCAAAGAAATTTTATACATTGTTTA
CATGATGAGGCCACAGTACTTACTGAGGACTTCATATGGTTTTTTTGTTTATTATTATTGAGAAAAGAGCTGAGGTTACCACATTCATTC
TTTGTGTTAGAAATGTAGGAGTGTGGTGGTTTTCTGCAATATTTAGAGCTTAGTCTCATAATTTGGAATTTAAGATAATAAGTAGTAACA
AGGCAAGTCTTTTATGTAAGACAGTCAAACAGTGTCACTTCAGGGACAAAGGCCTGGAAGCCCTTAAAATAAGTTATCTTAGATGTGCCA
GAACATATTCAGAGCTTTATTCCTTTAAGCTTAAGGCTTCAATACTTGTAGAAATGCAAATATTCTTGAGAAATGATACATTTTTTGTTC
TCAATTTCTCAATTCTACATACCTGATTATGAGTGAAGTATCCAAAGCAGGTTTTCATCAGCATGGGGGATGGAAGGTAGGTATAATATG
AGGACAATGGAAACTTTGGGAGAAGGGAGTGAGGAAATGGATAAAGAGAAATTTGAAAATTTTAGGCTGGACTTGAGCACTATTGCTGCT
TTCCTATGAACTATCAGAATGTTTAAATGCTTTATCATTCATGGTCCACTCTCAACCAACATTTATTATCCTTTAGTAATTAAACAATGG
TTTTACATACATTTTTATAATGTAGAAGGAAATTCAAGATTCCATAATCGTAAAATTTTTCAGATTTGTCTAATGTGTAATTTGTGCATC
TTCACATGCTGCTAAATGCAGATTTAAACATTACATCTGAGGATCATGACTTTTCCTCCTTTCTTGGAGATCTTGGTATAAAATTCATCT
GCTGTTATAAAATCAGGTTTCTACAGAGTTCGTTTCACACTAAAGGTAGTTTGTTACTGTTTGCATGAGGAAACCATGTATGTCTCAATC
TTTAATTTTAGGTGGTAGTGTTTATTGTTCACCCTCCCTCTTGCCTCCAAAAGAATGCTGAATTATACGCCAATATTTCCATGTGTATTC

>1993_1993_1_ADAM22-RUNDC3B_ADAM22_chr7_87607727_ENST00000265727_RUNDC3B_chr7_87445456_ENST00000338056_length(amino acids)=196AA_BP=108
MQAAVAVSVPFLLLCVLGTCPPARCGQAGDASLMELEKRKENRFVERQSIVPLRLIYRSGGEDESRHDALDTRVRGDLGGPQLTHVDQAS
FQVDAFGTSFILDVVLNQKSYQSLDQLSAEVSLSQTSLDPGQSQEGDGKQDTLNVMSEGKEDTPSLLGLCGSLTSVASYKSLTSLKSNDY

--------------------------------------------------------------
>1993_1993_2_ADAM22-RUNDC3B_ADAM22_chr7_87607727_ENST00000265727_RUNDC3B_chr7_87445456_ENST00000394654_length(transcript)=1154nt_BP=402nt
GCGGAGCGAGGGAAACGGACTCGGCGGCGCCGGCATGAGGAGCTGAGCGTCTCGGGCGAGGCGGGCTGACGGCAGCACCATGCAGGCGGC
AGTGGCTGTGTCCGTGCCCTTCTTGCTGCTCTGTGTCCTGGGGACCTGCCCTCCGGCGCGCTGCGGCCAGGCAGGAGACGCCTCATTGAT
GGAGCTAGAGAAGAGGAAGGAAAACCGCTTCGTGGAGCGCCAGAGCATCGTGCCACTGCGCCTCATCTACCGCTCGGGCGGCGAAGACGA
AAGTCGGCACGACGCGCTCGACACGCGGGTGCGGGGCGACCTCGGTGGCCCGCAGTTGACTCATGTTGACCAAGCAAGCTTCCAGGTTGA
TGCCTTTGGAACGTCATTCATTCTCGATGTCGTGCTAAATCAGAAAAGTTATCAAAGTCTTGACCAGTTATCAGCAGAAGTTAGCCTTTC
TCAGACTTCACTAGATCCAGGCCAGTCACAAGAAGGAGATGGAAAACAAGACACATTAAATGTAATGAGTGAAGGTAAGGAAGATACTCC
CTCATTACTTGGCCTCTGTGGATCTCTAACGTCAGTGGCAAGTTACAAGTCTCTAACAAGCTTAAAATCTAATGACTACCTTGCAAGTCC
TACAACAGAGATGACAAGTCCAGGCCTAACTCCATCCTGAAAATTTTTGTGTAAAAGCCAAAACTTTTTATGTTGTAAATGTTTAATTTA
CATGTTTGACTGCTGGGAAGACCTTTGAAATTTTATATTGTTCTGGTACATGTCTGAAATTCTATTGCTTGGAGAGAATCCCCTCCAGAT
AAGAGATTTTGAGTGAAAAACATAATGATCCTGCCATTTTTCATTTTTAAAATTCTTACATTTGTCATTGAGAAAGTTCAAAATGGAATA
GGCTTTAAAAAAAAAAAAACTTTCAAAGATCCGCCAAATCATTCATAGCAAATTGTACATATTGTTCAGCTGATTTTTATATATTTAAAT
ACACCTTAGTGGCCAGAGACTGACTTCAAGGTTTTATTCCAGAGACTCCAGAGACTTAAGCTAAGTATTTTTTCATTCTTTCAGATTTTC

>1993_1993_2_ADAM22-RUNDC3B_ADAM22_chr7_87607727_ENST00000265727_RUNDC3B_chr7_87445456_ENST00000394654_length(amino acids)=196AA_BP=108
MQAAVAVSVPFLLLCVLGTCPPARCGQAGDASLMELEKRKENRFVERQSIVPLRLIYRSGGEDESRHDALDTRVRGDLGGPQLTHVDQAS
FQVDAFGTSFILDVVLNQKSYQSLDQLSAEVSLSQTSLDPGQSQEGDGKQDTLNVMSEGKEDTPSLLGLCGSLTSVASYKSLTSLKSNDY

--------------------------------------------------------------
>1993_1993_3_ADAM22-RUNDC3B_ADAM22_chr7_87607727_ENST00000265727_RUNDC3B_chr7_87445456_ENST00000493037_length(transcript)=1096nt_BP=402nt
GCGGAGCGAGGGAAACGGACTCGGCGGCGCCGGCATGAGGAGCTGAGCGTCTCGGGCGAGGCGGGCTGACGGCAGCACCATGCAGGCGGC
AGTGGCTGTGTCCGTGCCCTTCTTGCTGCTCTGTGTCCTGGGGACCTGCCCTCCGGCGCGCTGCGGCCAGGCAGGAGACGCCTCATTGAT
GGAGCTAGAGAAGAGGAAGGAAAACCGCTTCGTGGAGCGCCAGAGCATCGTGCCACTGCGCCTCATCTACCGCTCGGGCGGCGAAGACGA
AAGTCGGCACGACGCGCTCGACACGCGGGTGCGGGGCGACCTCGGTGGCCCGCAGTTGACTCATGTTGACCAAGCAAGCTTCCAGGTTGA
TGCCTTTGGAACGTCATTCATTCTCGATGTCGTGCTAAATCAGAAAAGTTATCAAAGTCTTGACCAGTTATCAGCAGAAGTTAGCCTTTC
TCAGACTTCACTAGATCCAGGCCAGTCACAAGAAGGAGATGGAAAACAAGACACATTAAATGTAATGAGTGAAGGTAAGGAAGATACTCC
CTCATTACTTGGCCTCTGTGGATCTCTAACGTCAGTGGCAAGTTACAAGTCTCTAACAAGCTTAAAATCTAATGACTACCTTGCAAGTCC
TACAACAGAGATGACAAGTCCAGGCCTAACTCCATCCTGAAAATTTTTGTGTAAAAGCCAAAACTTTTTATGTTGTAAATGTTTAATTTA
CATGTTTGACTGCTGGGAAGACCTTTGAAATTTTATATTGTTCTGGTACATGTCTGAAATTCTATTGCTTGGAGAGAATCCCCTCCAGAT
AAGAGATTTTGAGTGAAAAACATAATGATCCTGCCATTTTTCATTTTTAAAATTCTTACATTTGTCATTGAGAAAGTTCAAAATGGAATA
GGCTTTAAAAAAAAAAAAACTTTCAAAGATCCGCCAAATCATTCATAGCAAATTGTACATATTGTTCAGCTGATTTTTATATATTTAAAT
ACACCTTAGTGGCCAGAGACTGACTTCAAGGTTTTATTCCAGAGACTCCAGAGACTTAAGCTAAGTATTTTTTCATTCTTTCAGATTTTC

>1993_1993_3_ADAM22-RUNDC3B_ADAM22_chr7_87607727_ENST00000265727_RUNDC3B_chr7_87445456_ENST00000493037_length(amino acids)=196AA_BP=108
MQAAVAVSVPFLLLCVLGTCPPARCGQAGDASLMELEKRKENRFVERQSIVPLRLIYRSGGEDESRHDALDTRVRGDLGGPQLTHVDQAS
FQVDAFGTSFILDVVLNQKSYQSLDQLSAEVSLSQTSLDPGQSQEGDGKQDTLNVMSEGKEDTPSLLGLCGSLTSVASYKSLTSLKSNDY

--------------------------------------------------------------
>1993_1993_4_ADAM22-RUNDC3B_ADAM22_chr7_87607727_ENST00000315984_RUNDC3B_chr7_87445456_ENST00000338056_length(transcript)=2936nt_BP=402nt
GCGGAGCGAGGGAAACGGACTCGGCGGCGCCGGCATGAGGAGCTGAGCGTCTCGGGCGAGGCGGGCTGACGGCAGCACCATGCAGGCGGC
AGTGGCTGTGTCCGTGCCCTTCTTGCTGCTCTGTGTCCTGGGGACCTGCCCTCCGGCGCGCTGCGGCCAGGCAGGAGACGCCTCATTGAT
GGAGCTAGAGAAGAGGAAGGAAAACCGCTTCGTGGAGCGCCAGAGCATCGTGCCACTGCGCCTCATCTACCGCTCGGGCGGCGAAGACGA
AAGTCGGCACGACGCGCTCGACACGCGGGTGCGGGGCGACCTCGGTGGCCCGCAGTTGACTCATGTTGACCAAGCAAGCTTCCAGGTTGA
TGCCTTTGGAACGTCATTCATTCTCGATGTCGTGCTAAATCAGAAAAGTTATCAAAGTCTTGACCAGTTATCAGCAGAAGTTAGCCTTTC
TCAGACTTCACTAGATCCAGGCCAGTCACAAGAAGGAGATGGAAAACAAGACACATTAAATGTAATGAGTGAAGGTAAGGAAGATACTCC
CTCATTACTTGGCCTCTGTGGATCTCTAACGTCAGTGGCAAGTTACAAGTCTCTAACAAGCTTAAAATCTAATGACTACCTTGCAAGTCC
TACAACAGAGATGACAAGTCCAGGCCTAACTCCATCCTGAAAATTTTTGTGTAAAAGCCAAAACTTTTTATGTTGTAAATGTTTAATTTA
CATGTTTGACTGCTGGGAAGACCTTTGAAATTTTATATTGTTCTGGTACATGTCTGAAATTCTATTGCTTGGAGAGAATCCCCTCCAGAT
AAGAGATTTTGAGTGAAAAACATAATGATCCTGCCATTTTTCATTTTTAAAATTCTTACATTTGTCATTGAGAAAGTTCAAAATGGAATA
GGCTTTAAAAAAAAAAAAACTTTCAAAGATCCGCCAAATCATTCATAGCAAATTGTACATATTGTTCAGCTGATTTTTATATATTTAAAT
ACACCTTAGTGGCCAGAGACTGACTTCAAGGTTTTATTCCAGAGACTCCAGAGACTTAAGCTAAGTATTTTTTCATTCTTTCAGATTTTC
AAAAAAAAAAAAAAAAAAAGTTAATTTCATTTTTTCATTAATGTCTTCCTAAGTTCTATGCTTTAAATGCCTTGTTTTTAATAACGGGAA
AGTTCTCAGCTGCATTTTCACAGTGGCTTATTCAGTTTTTCTTTAATATTTACCATTTGGTATCAATTCAGCATTCCACTTAACATTTTA
TAAATTCCATAGGAACATGCCTGTTTTGGTAGTTACTGACTTAATTTGTTAGTGCCACAAGGAAAATATTTTACAGTATTTTATGCCATT
TAGGCAAAATGAATAAACTGTTTTCCAAGATTTTCTTAAAAGATTATCAATTTAAAAGTATGATCAAGTATGCCTCAAAAACTAGAAACA
TTTCAAAATGTAGAACAAACGTTGAAAAATTGTTTTGCCAGGAAAGAGTTCAAGTTCAGTTAAGGATTTGAGAGGCTTTTAAACAAGGAT
CAGTAGGATAGTTATCATATTTACTTAATATATGTCTGATATTCAGTGCTGGTTCTTTTTCCTGTTTGTGCAACAATGAAGTGTGTCATG
TGTGTTTTATAGCCTCTATCATTAATCACACCAGAGTCTCATTTTAAAACATTTTAATGTTAAAACATCCCCACACTTATACACAGGTAA
AATTAGTTTTTTTTTTTTTAAAGTTGTAATCTGTACTTTTTTTTTTTTGCAATTTTTGAAACAGCTACATTAATCCCTAAAAATCCCACC
ATACTGAAAATGTATGGCGTGTATTTTCTATAGTAAGTAATATGAGGAAAACATGATTAGCTGTGCCAAAGAAATTTTATACATTGTTTA
CATGATGAGGCCACAGTACTTACTGAGGACTTCATATGGTTTTTTTGTTTATTATTATTGAGAAAAGAGCTGAGGTTACCACATTCATTC
TTTGTGTTAGAAATGTAGGAGTGTGGTGGTTTTCTGCAATATTTAGAGCTTAGTCTCATAATTTGGAATTTAAGATAATAAGTAGTAACA
AGGCAAGTCTTTTATGTAAGACAGTCAAACAGTGTCACTTCAGGGACAAAGGCCTGGAAGCCCTTAAAATAAGTTATCTTAGATGTGCCA
GAACATATTCAGAGCTTTATTCCTTTAAGCTTAAGGCTTCAATACTTGTAGAAATGCAAATATTCTTGAGAAATGATACATTTTTTGTTC
TCAATTTCTCAATTCTACATACCTGATTATGAGTGAAGTATCCAAAGCAGGTTTTCATCAGCATGGGGGATGGAAGGTAGGTATAATATG
AGGACAATGGAAACTTTGGGAGAAGGGAGTGAGGAAATGGATAAAGAGAAATTTGAAAATTTTAGGCTGGACTTGAGCACTATTGCTGCT
TTCCTATGAACTATCAGAATGTTTAAATGCTTTATCATTCATGGTCCACTCTCAACCAACATTTATTATCCTTTAGTAATTAAACAATGG
TTTTACATACATTTTTATAATGTAGAAGGAAATTCAAGATTCCATAATCGTAAAATTTTTCAGATTTGTCTAATGTGTAATTTGTGCATC
TTCACATGCTGCTAAATGCAGATTTAAACATTACATCTGAGGATCATGACTTTTCCTCCTTTCTTGGAGATCTTGGTATAAAATTCATCT
GCTGTTATAAAATCAGGTTTCTACAGAGTTCGTTTCACACTAAAGGTAGTTTGTTACTGTTTGCATGAGGAAACCATGTATGTCTCAATC
TTTAATTTTAGGTGGTAGTGTTTATTGTTCACCCTCCCTCTTGCCTCCAAAAGAATGCTGAATTATACGCCAATATTTCCATGTGTATTC

>1993_1993_4_ADAM22-RUNDC3B_ADAM22_chr7_87607727_ENST00000315984_RUNDC3B_chr7_87445456_ENST00000338056_length(amino acids)=196AA_BP=108
MQAAVAVSVPFLLLCVLGTCPPARCGQAGDASLMELEKRKENRFVERQSIVPLRLIYRSGGEDESRHDALDTRVRGDLGGPQLTHVDQAS
FQVDAFGTSFILDVVLNQKSYQSLDQLSAEVSLSQTSLDPGQSQEGDGKQDTLNVMSEGKEDTPSLLGLCGSLTSVASYKSLTSLKSNDY

--------------------------------------------------------------
>1993_1993_5_ADAM22-RUNDC3B_ADAM22_chr7_87607727_ENST00000315984_RUNDC3B_chr7_87445456_ENST00000394654_length(transcript)=1154nt_BP=402nt
GCGGAGCGAGGGAAACGGACTCGGCGGCGCCGGCATGAGGAGCTGAGCGTCTCGGGCGAGGCGGGCTGACGGCAGCACCATGCAGGCGGC
AGTGGCTGTGTCCGTGCCCTTCTTGCTGCTCTGTGTCCTGGGGACCTGCCCTCCGGCGCGCTGCGGCCAGGCAGGAGACGCCTCATTGAT
GGAGCTAGAGAAGAGGAAGGAAAACCGCTTCGTGGAGCGCCAGAGCATCGTGCCACTGCGCCTCATCTACCGCTCGGGCGGCGAAGACGA
AAGTCGGCACGACGCGCTCGACACGCGGGTGCGGGGCGACCTCGGTGGCCCGCAGTTGACTCATGTTGACCAAGCAAGCTTCCAGGTTGA
TGCCTTTGGAACGTCATTCATTCTCGATGTCGTGCTAAATCAGAAAAGTTATCAAAGTCTTGACCAGTTATCAGCAGAAGTTAGCCTTTC
TCAGACTTCACTAGATCCAGGCCAGTCACAAGAAGGAGATGGAAAACAAGACACATTAAATGTAATGAGTGAAGGTAAGGAAGATACTCC
CTCATTACTTGGCCTCTGTGGATCTCTAACGTCAGTGGCAAGTTACAAGTCTCTAACAAGCTTAAAATCTAATGACTACCTTGCAAGTCC
TACAACAGAGATGACAAGTCCAGGCCTAACTCCATCCTGAAAATTTTTGTGTAAAAGCCAAAACTTTTTATGTTGTAAATGTTTAATTTA
CATGTTTGACTGCTGGGAAGACCTTTGAAATTTTATATTGTTCTGGTACATGTCTGAAATTCTATTGCTTGGAGAGAATCCCCTCCAGAT
AAGAGATTTTGAGTGAAAAACATAATGATCCTGCCATTTTTCATTTTTAAAATTCTTACATTTGTCATTGAGAAAGTTCAAAATGGAATA
GGCTTTAAAAAAAAAAAAACTTTCAAAGATCCGCCAAATCATTCATAGCAAATTGTACATATTGTTCAGCTGATTTTTATATATTTAAAT
ACACCTTAGTGGCCAGAGACTGACTTCAAGGTTTTATTCCAGAGACTCCAGAGACTTAAGCTAAGTATTTTTTCATTCTTTCAGATTTTC

>1993_1993_5_ADAM22-RUNDC3B_ADAM22_chr7_87607727_ENST00000315984_RUNDC3B_chr7_87445456_ENST00000394654_length(amino acids)=196AA_BP=108
MQAAVAVSVPFLLLCVLGTCPPARCGQAGDASLMELEKRKENRFVERQSIVPLRLIYRSGGEDESRHDALDTRVRGDLGGPQLTHVDQAS
FQVDAFGTSFILDVVLNQKSYQSLDQLSAEVSLSQTSLDPGQSQEGDGKQDTLNVMSEGKEDTPSLLGLCGSLTSVASYKSLTSLKSNDY

--------------------------------------------------------------
>1993_1993_6_ADAM22-RUNDC3B_ADAM22_chr7_87607727_ENST00000315984_RUNDC3B_chr7_87445456_ENST00000493037_length(transcript)=1096nt_BP=402nt
GCGGAGCGAGGGAAACGGACTCGGCGGCGCCGGCATGAGGAGCTGAGCGTCTCGGGCGAGGCGGGCTGACGGCAGCACCATGCAGGCGGC
AGTGGCTGTGTCCGTGCCCTTCTTGCTGCTCTGTGTCCTGGGGACCTGCCCTCCGGCGCGCTGCGGCCAGGCAGGAGACGCCTCATTGAT
GGAGCTAGAGAAGAGGAAGGAAAACCGCTTCGTGGAGCGCCAGAGCATCGTGCCACTGCGCCTCATCTACCGCTCGGGCGGCGAAGACGA
AAGTCGGCACGACGCGCTCGACACGCGGGTGCGGGGCGACCTCGGTGGCCCGCAGTTGACTCATGTTGACCAAGCAAGCTTCCAGGTTGA
TGCCTTTGGAACGTCATTCATTCTCGATGTCGTGCTAAATCAGAAAAGTTATCAAAGTCTTGACCAGTTATCAGCAGAAGTTAGCCTTTC
TCAGACTTCACTAGATCCAGGCCAGTCACAAGAAGGAGATGGAAAACAAGACACATTAAATGTAATGAGTGAAGGTAAGGAAGATACTCC
CTCATTACTTGGCCTCTGTGGATCTCTAACGTCAGTGGCAAGTTACAAGTCTCTAACAAGCTTAAAATCTAATGACTACCTTGCAAGTCC
TACAACAGAGATGACAAGTCCAGGCCTAACTCCATCCTGAAAATTTTTGTGTAAAAGCCAAAACTTTTTATGTTGTAAATGTTTAATTTA
CATGTTTGACTGCTGGGAAGACCTTTGAAATTTTATATTGTTCTGGTACATGTCTGAAATTCTATTGCTTGGAGAGAATCCCCTCCAGAT
AAGAGATTTTGAGTGAAAAACATAATGATCCTGCCATTTTTCATTTTTAAAATTCTTACATTTGTCATTGAGAAAGTTCAAAATGGAATA
GGCTTTAAAAAAAAAAAAACTTTCAAAGATCCGCCAAATCATTCATAGCAAATTGTACATATTGTTCAGCTGATTTTTATATATTTAAAT
ACACCTTAGTGGCCAGAGACTGACTTCAAGGTTTTATTCCAGAGACTCCAGAGACTTAAGCTAAGTATTTTTTCATTCTTTCAGATTTTC

>1993_1993_6_ADAM22-RUNDC3B_ADAM22_chr7_87607727_ENST00000315984_RUNDC3B_chr7_87445456_ENST00000493037_length(amino acids)=196AA_BP=108
MQAAVAVSVPFLLLCVLGTCPPARCGQAGDASLMELEKRKENRFVERQSIVPLRLIYRSGGEDESRHDALDTRVRGDLGGPQLTHVDQAS
FQVDAFGTSFILDVVLNQKSYQSLDQLSAEVSLSQTSLDPGQSQEGDGKQDTLNVMSEGKEDTPSLLGLCGSLTSVASYKSLTSLKSNDY

--------------------------------------------------------------
>1993_1993_7_ADAM22-RUNDC3B_ADAM22_chr7_87607727_ENST00000398201_RUNDC3B_chr7_87445456_ENST00000338056_length(transcript)=2976nt_BP=442nt
GCCGGGGCTGGGTGGAGGTGGCCGCGGGGACCCCGGGGGCGCGGAGCGAGGGAAACGGACTCGGCGGCGCCGGCATGAGGAGCTGAGCGT
CTCGGGCGAGGCGGGCTGACGGCAGCACCATGCAGGCGGCAGTGGCTGTGTCCGTGCCCTTCTTGCTGCTCTGTGTCCTGGGGACCTGCC
CTCCGGCGCGCTGCGGCCAGGCAGGAGACGCCTCATTGATGGAGCTAGAGAAGAGGAAGGAAAACCGCTTCGTGGAGCGCCAGAGCATCG
TGCCACTGCGCCTCATCTACCGCTCGGGCGGCGAAGACGAAAGTCGGCACGACGCGCTCGACACGCGGGTGCGGGGCGACCTCGGTGGCC
CGCAGTTGACTCATGTTGACCAAGCAAGCTTCCAGGTTGATGCCTTTGGAACGTCATTCATTCTCGATGTCGTGCTAAATCAGAAAAGTT
ATCAAAGTCTTGACCAGTTATCAGCAGAAGTTAGCCTTTCTCAGACTTCACTAGATCCAGGCCAGTCACAAGAAGGAGATGGAAAACAAG
ACACATTAAATGTAATGAGTGAAGGTAAGGAAGATACTCCCTCATTACTTGGCCTCTGTGGATCTCTAACGTCAGTGGCAAGTTACAAGT
CTCTAACAAGCTTAAAATCTAATGACTACCTTGCAAGTCCTACAACAGAGATGACAAGTCCAGGCCTAACTCCATCCTGAAAATTTTTGT
GTAAAAGCCAAAACTTTTTATGTTGTAAATGTTTAATTTACATGTTTGACTGCTGGGAAGACCTTTGAAATTTTATATTGTTCTGGTACA
TGTCTGAAATTCTATTGCTTGGAGAGAATCCCCTCCAGATAAGAGATTTTGAGTGAAAAACATAATGATCCTGCCATTTTTCATTTTTAA
AATTCTTACATTTGTCATTGAGAAAGTTCAAAATGGAATAGGCTTTAAAAAAAAAAAAACTTTCAAAGATCCGCCAAATCATTCATAGCA
AATTGTACATATTGTTCAGCTGATTTTTATATATTTAAATACACCTTAGTGGCCAGAGACTGACTTCAAGGTTTTATTCCAGAGACTCCA
GAGACTTAAGCTAAGTATTTTTTCATTCTTTCAGATTTTCAAAAAAAAAAAAAAAAAAAGTTAATTTCATTTTTTCATTAATGTCTTCCT
AAGTTCTATGCTTTAAATGCCTTGTTTTTAATAACGGGAAAGTTCTCAGCTGCATTTTCACAGTGGCTTATTCAGTTTTTCTTTAATATT
TACCATTTGGTATCAATTCAGCATTCCACTTAACATTTTATAAATTCCATAGGAACATGCCTGTTTTGGTAGTTACTGACTTAATTTGTT
AGTGCCACAAGGAAAATATTTTACAGTATTTTATGCCATTTAGGCAAAATGAATAAACTGTTTTCCAAGATTTTCTTAAAAGATTATCAA
TTTAAAAGTATGATCAAGTATGCCTCAAAAACTAGAAACATTTCAAAATGTAGAACAAACGTTGAAAAATTGTTTTGCCAGGAAAGAGTT
CAAGTTCAGTTAAGGATTTGAGAGGCTTTTAAACAAGGATCAGTAGGATAGTTATCATATTTACTTAATATATGTCTGATATTCAGTGCT
GGTTCTTTTTCCTGTTTGTGCAACAATGAAGTGTGTCATGTGTGTTTTATAGCCTCTATCATTAATCACACCAGAGTCTCATTTTAAAAC
ATTTTAATGTTAAAACATCCCCACACTTATACACAGGTAAAATTAGTTTTTTTTTTTTTAAAGTTGTAATCTGTACTTTTTTTTTTTTGC
AATTTTTGAAACAGCTACATTAATCCCTAAAAATCCCACCATACTGAAAATGTATGGCGTGTATTTTCTATAGTAAGTAATATGAGGAAA
ACATGATTAGCTGTGCCAAAGAAATTTTATACATTGTTTACATGATGAGGCCACAGTACTTACTGAGGACTTCATATGGTTTTTTTGTTT
ATTATTATTGAGAAAAGAGCTGAGGTTACCACATTCATTCTTTGTGTTAGAAATGTAGGAGTGTGGTGGTTTTCTGCAATATTTAGAGCT
TAGTCTCATAATTTGGAATTTAAGATAATAAGTAGTAACAAGGCAAGTCTTTTATGTAAGACAGTCAAACAGTGTCACTTCAGGGACAAA
GGCCTGGAAGCCCTTAAAATAAGTTATCTTAGATGTGCCAGAACATATTCAGAGCTTTATTCCTTTAAGCTTAAGGCTTCAATACTTGTA
GAAATGCAAATATTCTTGAGAAATGATACATTTTTTGTTCTCAATTTCTCAATTCTACATACCTGATTATGAGTGAAGTATCCAAAGCAG
GTTTTCATCAGCATGGGGGATGGAAGGTAGGTATAATATGAGGACAATGGAAACTTTGGGAGAAGGGAGTGAGGAAATGGATAAAGAGAA
ATTTGAAAATTTTAGGCTGGACTTGAGCACTATTGCTGCTTTCCTATGAACTATCAGAATGTTTAAATGCTTTATCATTCATGGTCCACT
CTCAACCAACATTTATTATCCTTTAGTAATTAAACAATGGTTTTACATACATTTTTATAATGTAGAAGGAAATTCAAGATTCCATAATCG
TAAAATTTTTCAGATTTGTCTAATGTGTAATTTGTGCATCTTCACATGCTGCTAAATGCAGATTTAAACATTACATCTGAGGATCATGAC
TTTTCCTCCTTTCTTGGAGATCTTGGTATAAAATTCATCTGCTGTTATAAAATCAGGTTTCTACAGAGTTCGTTTCACACTAAAGGTAGT
TTGTTACTGTTTGCATGAGGAAACCATGTATGTCTCAATCTTTAATTTTAGGTGGTAGTGTTTATTGTTCACCCTCCCTCTTGCCTCCAA
AAGAATGCTGAATTATACGCCAATATTTCCATGTGTATTCTGTTGCCTTGATGCGTACTATACTTGTTGCATGTATATTAAAAATTTTGT

>1993_1993_7_ADAM22-RUNDC3B_ADAM22_chr7_87607727_ENST00000398201_RUNDC3B_chr7_87445456_ENST00000338056_length(amino acids)=196AA_BP=108
MQAAVAVSVPFLLLCVLGTCPPARCGQAGDASLMELEKRKENRFVERQSIVPLRLIYRSGGEDESRHDALDTRVRGDLGGPQLTHVDQAS
FQVDAFGTSFILDVVLNQKSYQSLDQLSAEVSLSQTSLDPGQSQEGDGKQDTLNVMSEGKEDTPSLLGLCGSLTSVASYKSLTSLKSNDY

--------------------------------------------------------------
>1993_1993_8_ADAM22-RUNDC3B_ADAM22_chr7_87607727_ENST00000398201_RUNDC3B_chr7_87445456_ENST00000394654_length(transcript)=1194nt_BP=442nt
GCCGGGGCTGGGTGGAGGTGGCCGCGGGGACCCCGGGGGCGCGGAGCGAGGGAAACGGACTCGGCGGCGCCGGCATGAGGAGCTGAGCGT
CTCGGGCGAGGCGGGCTGACGGCAGCACCATGCAGGCGGCAGTGGCTGTGTCCGTGCCCTTCTTGCTGCTCTGTGTCCTGGGGACCTGCC
CTCCGGCGCGCTGCGGCCAGGCAGGAGACGCCTCATTGATGGAGCTAGAGAAGAGGAAGGAAAACCGCTTCGTGGAGCGCCAGAGCATCG
TGCCACTGCGCCTCATCTACCGCTCGGGCGGCGAAGACGAAAGTCGGCACGACGCGCTCGACACGCGGGTGCGGGGCGACCTCGGTGGCC
CGCAGTTGACTCATGTTGACCAAGCAAGCTTCCAGGTTGATGCCTTTGGAACGTCATTCATTCTCGATGTCGTGCTAAATCAGAAAAGTT
ATCAAAGTCTTGACCAGTTATCAGCAGAAGTTAGCCTTTCTCAGACTTCACTAGATCCAGGCCAGTCACAAGAAGGAGATGGAAAACAAG
ACACATTAAATGTAATGAGTGAAGGTAAGGAAGATACTCCCTCATTACTTGGCCTCTGTGGATCTCTAACGTCAGTGGCAAGTTACAAGT
CTCTAACAAGCTTAAAATCTAATGACTACCTTGCAAGTCCTACAACAGAGATGACAAGTCCAGGCCTAACTCCATCCTGAAAATTTTTGT
GTAAAAGCCAAAACTTTTTATGTTGTAAATGTTTAATTTACATGTTTGACTGCTGGGAAGACCTTTGAAATTTTATATTGTTCTGGTACA
TGTCTGAAATTCTATTGCTTGGAGAGAATCCCCTCCAGATAAGAGATTTTGAGTGAAAAACATAATGATCCTGCCATTTTTCATTTTTAA
AATTCTTACATTTGTCATTGAGAAAGTTCAAAATGGAATAGGCTTTAAAAAAAAAAAAACTTTCAAAGATCCGCCAAATCATTCATAGCA
AATTGTACATATTGTTCAGCTGATTTTTATATATTTAAATACACCTTAGTGGCCAGAGACTGACTTCAAGGTTTTATTCCAGAGACTCCA
GAGACTTAAGCTAAGTATTTTTTCATTCTTTCAGATTTTCAAAAAAAAAAAAAAAAAAAGTTAATTTCATTTTTTCATTAATGTCTTCCT

>1993_1993_8_ADAM22-RUNDC3B_ADAM22_chr7_87607727_ENST00000398201_RUNDC3B_chr7_87445456_ENST00000394654_length(amino acids)=196AA_BP=108
MQAAVAVSVPFLLLCVLGTCPPARCGQAGDASLMELEKRKENRFVERQSIVPLRLIYRSGGEDESRHDALDTRVRGDLGGPQLTHVDQAS
FQVDAFGTSFILDVVLNQKSYQSLDQLSAEVSLSQTSLDPGQSQEGDGKQDTLNVMSEGKEDTPSLLGLCGSLTSVASYKSLTSLKSNDY

--------------------------------------------------------------
>1993_1993_9_ADAM22-RUNDC3B_ADAM22_chr7_87607727_ENST00000398201_RUNDC3B_chr7_87445456_ENST00000493037_length(transcript)=1136nt_BP=442nt
GCCGGGGCTGGGTGGAGGTGGCCGCGGGGACCCCGGGGGCGCGGAGCGAGGGAAACGGACTCGGCGGCGCCGGCATGAGGAGCTGAGCGT
CTCGGGCGAGGCGGGCTGACGGCAGCACCATGCAGGCGGCAGTGGCTGTGTCCGTGCCCTTCTTGCTGCTCTGTGTCCTGGGGACCTGCC
CTCCGGCGCGCTGCGGCCAGGCAGGAGACGCCTCATTGATGGAGCTAGAGAAGAGGAAGGAAAACCGCTTCGTGGAGCGCCAGAGCATCG
TGCCACTGCGCCTCATCTACCGCTCGGGCGGCGAAGACGAAAGTCGGCACGACGCGCTCGACACGCGGGTGCGGGGCGACCTCGGTGGCC
CGCAGTTGACTCATGTTGACCAAGCAAGCTTCCAGGTTGATGCCTTTGGAACGTCATTCATTCTCGATGTCGTGCTAAATCAGAAAAGTT
ATCAAAGTCTTGACCAGTTATCAGCAGAAGTTAGCCTTTCTCAGACTTCACTAGATCCAGGCCAGTCACAAGAAGGAGATGGAAAACAAG
ACACATTAAATGTAATGAGTGAAGGTAAGGAAGATACTCCCTCATTACTTGGCCTCTGTGGATCTCTAACGTCAGTGGCAAGTTACAAGT
CTCTAACAAGCTTAAAATCTAATGACTACCTTGCAAGTCCTACAACAGAGATGACAAGTCCAGGCCTAACTCCATCCTGAAAATTTTTGT
GTAAAAGCCAAAACTTTTTATGTTGTAAATGTTTAATTTACATGTTTGACTGCTGGGAAGACCTTTGAAATTTTATATTGTTCTGGTACA
TGTCTGAAATTCTATTGCTTGGAGAGAATCCCCTCCAGATAAGAGATTTTGAGTGAAAAACATAATGATCCTGCCATTTTTCATTTTTAA
AATTCTTACATTTGTCATTGAGAAAGTTCAAAATGGAATAGGCTTTAAAAAAAAAAAAACTTTCAAAGATCCGCCAAATCATTCATAGCA
AATTGTACATATTGTTCAGCTGATTTTTATATATTTAAATACACCTTAGTGGCCAGAGACTGACTTCAAGGTTTTATTCCAGAGACTCCA

>1993_1993_9_ADAM22-RUNDC3B_ADAM22_chr7_87607727_ENST00000398201_RUNDC3B_chr7_87445456_ENST00000493037_length(amino acids)=196AA_BP=108
MQAAVAVSVPFLLLCVLGTCPPARCGQAGDASLMELEKRKENRFVERQSIVPLRLIYRSGGEDESRHDALDTRVRGDLGGPQLTHVDQAS
FQVDAFGTSFILDVVLNQKSYQSLDQLSAEVSLSQTSLDPGQSQEGDGKQDTLNVMSEGKEDTPSLLGLCGSLTSVASYKSLTSLKSNDY

--------------------------------------------------------------
>1993_1993_10_ADAM22-RUNDC3B_ADAM22_chr7_87607727_ENST00000398204_RUNDC3B_chr7_87445456_ENST00000338056_length(transcript)=3180nt_BP=646nt
CGGGCGCTCGCTCCCTGCCGAGCTCTTGTCGCCCGCCCGAGCCTTTGCCAGGGGATGAGGTGGGAGGCGCTAGAAACCACTTAGCTACAG
CCAACCGCCCAATGCAGCACTCGCTCGCTCCCCCCGCCAGCGGAAGCGTCCGCGAAGCACAATGCAGCACTGAGCCGCGGTGGAGGTTGC
AGCGCCACGGCCGCCGCAGCACCGGCCGGGGCTGGGTGGAGGTGGCCGCGGGGACCCCGGGGGCGCGGAGCGAGGGAAACGGACTCGGCG
GCGCCGGCATGAGGAGCTGAGCGTCTCGGGCGAGGCGGGCTGACGGCAGCACCATGCAGGCGGCAGTGGCTGTGTCCGTGCCCTTCTTGC
TGCTCTGTGTCCTGGGGACCTGCCCTCCGGCGCGCTGCGGCCAGGCAGGAGACGCCTCATTGATGGAGCTAGAGAAGAGGAAGGAAAACC
GCTTCGTGGAGCGCCAGAGCATCGTGCCACTGCGCCTCATCTACCGCTCGGGCGGCGAAGACGAAAGTCGGCACGACGCGCTCGACACGC
GGGTGCGGGGCGACCTCGGTGGCCCGCAGTTGACTCATGTTGACCAAGCAAGCTTCCAGGTTGATGCCTTTGGAACGTCATTCATTCTCG
ATGTCGTGCTAAATCAGAAAAGTTATCAAAGTCTTGACCAGTTATCAGCAGAAGTTAGCCTTTCTCAGACTTCACTAGATCCAGGCCAGT
CACAAGAAGGAGATGGAAAACAAGACACATTAAATGTAATGAGTGAAGGTAAGGAAGATACTCCCTCATTACTTGGCCTCTGTGGATCTC
TAACGTCAGTGGCAAGTTACAAGTCTCTAACAAGCTTAAAATCTAATGACTACCTTGCAAGTCCTACAACAGAGATGACAAGTCCAGGCC
TAACTCCATCCTGAAAATTTTTGTGTAAAAGCCAAAACTTTTTATGTTGTAAATGTTTAATTTACATGTTTGACTGCTGGGAAGACCTTT
GAAATTTTATATTGTTCTGGTACATGTCTGAAATTCTATTGCTTGGAGAGAATCCCCTCCAGATAAGAGATTTTGAGTGAAAAACATAAT
GATCCTGCCATTTTTCATTTTTAAAATTCTTACATTTGTCATTGAGAAAGTTCAAAATGGAATAGGCTTTAAAAAAAAAAAAACTTTCAA
AGATCCGCCAAATCATTCATAGCAAATTGTACATATTGTTCAGCTGATTTTTATATATTTAAATACACCTTAGTGGCCAGAGACTGACTT
CAAGGTTTTATTCCAGAGACTCCAGAGACTTAAGCTAAGTATTTTTTCATTCTTTCAGATTTTCAAAAAAAAAAAAAAAAAAAGTTAATT
TCATTTTTTCATTAATGTCTTCCTAAGTTCTATGCTTTAAATGCCTTGTTTTTAATAACGGGAAAGTTCTCAGCTGCATTTTCACAGTGG
CTTATTCAGTTTTTCTTTAATATTTACCATTTGGTATCAATTCAGCATTCCACTTAACATTTTATAAATTCCATAGGAACATGCCTGTTT
TGGTAGTTACTGACTTAATTTGTTAGTGCCACAAGGAAAATATTTTACAGTATTTTATGCCATTTAGGCAAAATGAATAAACTGTTTTCC
AAGATTTTCTTAAAAGATTATCAATTTAAAAGTATGATCAAGTATGCCTCAAAAACTAGAAACATTTCAAAATGTAGAACAAACGTTGAA
AAATTGTTTTGCCAGGAAAGAGTTCAAGTTCAGTTAAGGATTTGAGAGGCTTTTAAACAAGGATCAGTAGGATAGTTATCATATTTACTT
AATATATGTCTGATATTCAGTGCTGGTTCTTTTTCCTGTTTGTGCAACAATGAAGTGTGTCATGTGTGTTTTATAGCCTCTATCATTAAT
CACACCAGAGTCTCATTTTAAAACATTTTAATGTTAAAACATCCCCACACTTATACACAGGTAAAATTAGTTTTTTTTTTTTTAAAGTTG
TAATCTGTACTTTTTTTTTTTTGCAATTTTTGAAACAGCTACATTAATCCCTAAAAATCCCACCATACTGAAAATGTATGGCGTGTATTT
TCTATAGTAAGTAATATGAGGAAAACATGATTAGCTGTGCCAAAGAAATTTTATACATTGTTTACATGATGAGGCCACAGTACTTACTGA
GGACTTCATATGGTTTTTTTGTTTATTATTATTGAGAAAAGAGCTGAGGTTACCACATTCATTCTTTGTGTTAGAAATGTAGGAGTGTGG
TGGTTTTCTGCAATATTTAGAGCTTAGTCTCATAATTTGGAATTTAAGATAATAAGTAGTAACAAGGCAAGTCTTTTATGTAAGACAGTC
AAACAGTGTCACTTCAGGGACAAAGGCCTGGAAGCCCTTAAAATAAGTTATCTTAGATGTGCCAGAACATATTCAGAGCTTTATTCCTTT
AAGCTTAAGGCTTCAATACTTGTAGAAATGCAAATATTCTTGAGAAATGATACATTTTTTGTTCTCAATTTCTCAATTCTACATACCTGA
TTATGAGTGAAGTATCCAAAGCAGGTTTTCATCAGCATGGGGGATGGAAGGTAGGTATAATATGAGGACAATGGAAACTTTGGGAGAAGG
GAGTGAGGAAATGGATAAAGAGAAATTTGAAAATTTTAGGCTGGACTTGAGCACTATTGCTGCTTTCCTATGAACTATCAGAATGTTTAA
ATGCTTTATCATTCATGGTCCACTCTCAACCAACATTTATTATCCTTTAGTAATTAAACAATGGTTTTACATACATTTTTATAATGTAGA
AGGAAATTCAAGATTCCATAATCGTAAAATTTTTCAGATTTGTCTAATGTGTAATTTGTGCATCTTCACATGCTGCTAAATGCAGATTTA
AACATTACATCTGAGGATCATGACTTTTCCTCCTTTCTTGGAGATCTTGGTATAAAATTCATCTGCTGTTATAAAATCAGGTTTCTACAG
AGTTCGTTTCACACTAAAGGTAGTTTGTTACTGTTTGCATGAGGAAACCATGTATGTCTCAATCTTTAATTTTAGGTGGTAGTGTTTATT
GTTCACCCTCCCTCTTGCCTCCAAAAGAATGCTGAATTATACGCCAATATTTCCATGTGTATTCTGTTGCCTTGATGCGTACTATACTTG

>1993_1993_10_ADAM22-RUNDC3B_ADAM22_chr7_87607727_ENST00000398204_RUNDC3B_chr7_87445456_ENST00000338056_length(amino acids)=196AA_BP=108
MQAAVAVSVPFLLLCVLGTCPPARCGQAGDASLMELEKRKENRFVERQSIVPLRLIYRSGGEDESRHDALDTRVRGDLGGPQLTHVDQAS
FQVDAFGTSFILDVVLNQKSYQSLDQLSAEVSLSQTSLDPGQSQEGDGKQDTLNVMSEGKEDTPSLLGLCGSLTSVASYKSLTSLKSNDY

--------------------------------------------------------------
>1993_1993_11_ADAM22-RUNDC3B_ADAM22_chr7_87607727_ENST00000398204_RUNDC3B_chr7_87445456_ENST00000394654_length(transcript)=1398nt_BP=646nt
CGGGCGCTCGCTCCCTGCCGAGCTCTTGTCGCCCGCCCGAGCCTTTGCCAGGGGATGAGGTGGGAGGCGCTAGAAACCACTTAGCTACAG
CCAACCGCCCAATGCAGCACTCGCTCGCTCCCCCCGCCAGCGGAAGCGTCCGCGAAGCACAATGCAGCACTGAGCCGCGGTGGAGGTTGC
AGCGCCACGGCCGCCGCAGCACCGGCCGGGGCTGGGTGGAGGTGGCCGCGGGGACCCCGGGGGCGCGGAGCGAGGGAAACGGACTCGGCG
GCGCCGGCATGAGGAGCTGAGCGTCTCGGGCGAGGCGGGCTGACGGCAGCACCATGCAGGCGGCAGTGGCTGTGTCCGTGCCCTTCTTGC
TGCTCTGTGTCCTGGGGACCTGCCCTCCGGCGCGCTGCGGCCAGGCAGGAGACGCCTCATTGATGGAGCTAGAGAAGAGGAAGGAAAACC
GCTTCGTGGAGCGCCAGAGCATCGTGCCACTGCGCCTCATCTACCGCTCGGGCGGCGAAGACGAAAGTCGGCACGACGCGCTCGACACGC
GGGTGCGGGGCGACCTCGGTGGCCCGCAGTTGACTCATGTTGACCAAGCAAGCTTCCAGGTTGATGCCTTTGGAACGTCATTCATTCTCG
ATGTCGTGCTAAATCAGAAAAGTTATCAAAGTCTTGACCAGTTATCAGCAGAAGTTAGCCTTTCTCAGACTTCACTAGATCCAGGCCAGT
CACAAGAAGGAGATGGAAAACAAGACACATTAAATGTAATGAGTGAAGGTAAGGAAGATACTCCCTCATTACTTGGCCTCTGTGGATCTC
TAACGTCAGTGGCAAGTTACAAGTCTCTAACAAGCTTAAAATCTAATGACTACCTTGCAAGTCCTACAACAGAGATGACAAGTCCAGGCC
TAACTCCATCCTGAAAATTTTTGTGTAAAAGCCAAAACTTTTTATGTTGTAAATGTTTAATTTACATGTTTGACTGCTGGGAAGACCTTT
GAAATTTTATATTGTTCTGGTACATGTCTGAAATTCTATTGCTTGGAGAGAATCCCCTCCAGATAAGAGATTTTGAGTGAAAAACATAAT
GATCCTGCCATTTTTCATTTTTAAAATTCTTACATTTGTCATTGAGAAAGTTCAAAATGGAATAGGCTTTAAAAAAAAAAAAACTTTCAA
AGATCCGCCAAATCATTCATAGCAAATTGTACATATTGTTCAGCTGATTTTTATATATTTAAATACACCTTAGTGGCCAGAGACTGACTT
CAAGGTTTTATTCCAGAGACTCCAGAGACTTAAGCTAAGTATTTTTTCATTCTTTCAGATTTTCAAAAAAAAAAAAAAAAAAAGTTAATT

>1993_1993_11_ADAM22-RUNDC3B_ADAM22_chr7_87607727_ENST00000398204_RUNDC3B_chr7_87445456_ENST00000394654_length(amino acids)=196AA_BP=108
MQAAVAVSVPFLLLCVLGTCPPARCGQAGDASLMELEKRKENRFVERQSIVPLRLIYRSGGEDESRHDALDTRVRGDLGGPQLTHVDQAS
FQVDAFGTSFILDVVLNQKSYQSLDQLSAEVSLSQTSLDPGQSQEGDGKQDTLNVMSEGKEDTPSLLGLCGSLTSVASYKSLTSLKSNDY

--------------------------------------------------------------
>1993_1993_12_ADAM22-RUNDC3B_ADAM22_chr7_87607727_ENST00000398204_RUNDC3B_chr7_87445456_ENST00000493037_length(transcript)=1340nt_BP=646nt
CGGGCGCTCGCTCCCTGCCGAGCTCTTGTCGCCCGCCCGAGCCTTTGCCAGGGGATGAGGTGGGAGGCGCTAGAAACCACTTAGCTACAG
CCAACCGCCCAATGCAGCACTCGCTCGCTCCCCCCGCCAGCGGAAGCGTCCGCGAAGCACAATGCAGCACTGAGCCGCGGTGGAGGTTGC
AGCGCCACGGCCGCCGCAGCACCGGCCGGGGCTGGGTGGAGGTGGCCGCGGGGACCCCGGGGGCGCGGAGCGAGGGAAACGGACTCGGCG
GCGCCGGCATGAGGAGCTGAGCGTCTCGGGCGAGGCGGGCTGACGGCAGCACCATGCAGGCGGCAGTGGCTGTGTCCGTGCCCTTCTTGC
TGCTCTGTGTCCTGGGGACCTGCCCTCCGGCGCGCTGCGGCCAGGCAGGAGACGCCTCATTGATGGAGCTAGAGAAGAGGAAGGAAAACC
GCTTCGTGGAGCGCCAGAGCATCGTGCCACTGCGCCTCATCTACCGCTCGGGCGGCGAAGACGAAAGTCGGCACGACGCGCTCGACACGC
GGGTGCGGGGCGACCTCGGTGGCCCGCAGTTGACTCATGTTGACCAAGCAAGCTTCCAGGTTGATGCCTTTGGAACGTCATTCATTCTCG
ATGTCGTGCTAAATCAGAAAAGTTATCAAAGTCTTGACCAGTTATCAGCAGAAGTTAGCCTTTCTCAGACTTCACTAGATCCAGGCCAGT
CACAAGAAGGAGATGGAAAACAAGACACATTAAATGTAATGAGTGAAGGTAAGGAAGATACTCCCTCATTACTTGGCCTCTGTGGATCTC
TAACGTCAGTGGCAAGTTACAAGTCTCTAACAAGCTTAAAATCTAATGACTACCTTGCAAGTCCTACAACAGAGATGACAAGTCCAGGCC
TAACTCCATCCTGAAAATTTTTGTGTAAAAGCCAAAACTTTTTATGTTGTAAATGTTTAATTTACATGTTTGACTGCTGGGAAGACCTTT
GAAATTTTATATTGTTCTGGTACATGTCTGAAATTCTATTGCTTGGAGAGAATCCCCTCCAGATAAGAGATTTTGAGTGAAAAACATAAT
GATCCTGCCATTTTTCATTTTTAAAATTCTTACATTTGTCATTGAGAAAGTTCAAAATGGAATAGGCTTTAAAAAAAAAAAAACTTTCAA
AGATCCGCCAAATCATTCATAGCAAATTGTACATATTGTTCAGCTGATTTTTATATATTTAAATACACCTTAGTGGCCAGAGACTGACTT

>1993_1993_12_ADAM22-RUNDC3B_ADAM22_chr7_87607727_ENST00000398204_RUNDC3B_chr7_87445456_ENST00000493037_length(amino acids)=196AA_BP=108
MQAAVAVSVPFLLLCVLGTCPPARCGQAGDASLMELEKRKENRFVERQSIVPLRLIYRSGGEDESRHDALDTRVRGDLGGPQLTHVDQAS
FQVDAFGTSFILDVVLNQKSYQSLDQLSAEVSLSQTSLDPGQSQEGDGKQDTLNVMSEGKEDTPSLLGLCGSLTSVASYKSLTSLKSNDY

--------------------------------------------------------------
>1993_1993_13_ADAM22-RUNDC3B_ADAM22_chr7_87607727_ENST00000398209_RUNDC3B_chr7_87445456_ENST00000338056_length(transcript)=2903nt_BP=369nt
CATGAGGAGCTGAGCGTCTCGGGCGAGGCGGGCTGACGGCAGCACCATGCAGGCGGCAGTGGCTGTGTCCGTGCCCTTCTTGCTGCTCTG
TGTCCTGGGGACCTGCCCTCCGGCGCGCTGCGGCCAGGCAGGAGACGCCTCATTGATGGAGCTAGAGAAGAGGAAGGAAAACCGCTTCGT
GGAGCGCCAGAGCATCGTGCCACTGCGCCTCATCTACCGCTCGGGCGGCGAAGACGAAAGTCGGCACGACGCGCTCGACACGCGGGTGCG
GGGCGACCTCGGTGGCCCGCAGTTGACTCATGTTGACCAAGCAAGCTTCCAGGTTGATGCCTTTGGAACGTCATTCATTCTCGATGTCGT
GCTAAATCAGAAAAGTTATCAAAGTCTTGACCAGTTATCAGCAGAAGTTAGCCTTTCTCAGACTTCACTAGATCCAGGCCAGTCACAAGA
AGGAGATGGAAAACAAGACACATTAAATGTAATGAGTGAAGGTAAGGAAGATACTCCCTCATTACTTGGCCTCTGTGGATCTCTAACGTC
AGTGGCAAGTTACAAGTCTCTAACAAGCTTAAAATCTAATGACTACCTTGCAAGTCCTACAACAGAGATGACAAGTCCAGGCCTAACTCC
ATCCTGAAAATTTTTGTGTAAAAGCCAAAACTTTTTATGTTGTAAATGTTTAATTTACATGTTTGACTGCTGGGAAGACCTTTGAAATTT
TATATTGTTCTGGTACATGTCTGAAATTCTATTGCTTGGAGAGAATCCCCTCCAGATAAGAGATTTTGAGTGAAAAACATAATGATCCTG
CCATTTTTCATTTTTAAAATTCTTACATTTGTCATTGAGAAAGTTCAAAATGGAATAGGCTTTAAAAAAAAAAAAACTTTCAAAGATCCG
CCAAATCATTCATAGCAAATTGTACATATTGTTCAGCTGATTTTTATATATTTAAATACACCTTAGTGGCCAGAGACTGACTTCAAGGTT
TTATTCCAGAGACTCCAGAGACTTAAGCTAAGTATTTTTTCATTCTTTCAGATTTTCAAAAAAAAAAAAAAAAAAAGTTAATTTCATTTT
TTCATTAATGTCTTCCTAAGTTCTATGCTTTAAATGCCTTGTTTTTAATAACGGGAAAGTTCTCAGCTGCATTTTCACAGTGGCTTATTC
AGTTTTTCTTTAATATTTACCATTTGGTATCAATTCAGCATTCCACTTAACATTTTATAAATTCCATAGGAACATGCCTGTTTTGGTAGT
TACTGACTTAATTTGTTAGTGCCACAAGGAAAATATTTTACAGTATTTTATGCCATTTAGGCAAAATGAATAAACTGTTTTCCAAGATTT
TCTTAAAAGATTATCAATTTAAAAGTATGATCAAGTATGCCTCAAAAACTAGAAACATTTCAAAATGTAGAACAAACGTTGAAAAATTGT
TTTGCCAGGAAAGAGTTCAAGTTCAGTTAAGGATTTGAGAGGCTTTTAAACAAGGATCAGTAGGATAGTTATCATATTTACTTAATATAT
GTCTGATATTCAGTGCTGGTTCTTTTTCCTGTTTGTGCAACAATGAAGTGTGTCATGTGTGTTTTATAGCCTCTATCATTAATCACACCA
GAGTCTCATTTTAAAACATTTTAATGTTAAAACATCCCCACACTTATACACAGGTAAAATTAGTTTTTTTTTTTTTAAAGTTGTAATCTG
TACTTTTTTTTTTTTGCAATTTTTGAAACAGCTACATTAATCCCTAAAAATCCCACCATACTGAAAATGTATGGCGTGTATTTTCTATAG
TAAGTAATATGAGGAAAACATGATTAGCTGTGCCAAAGAAATTTTATACATTGTTTACATGATGAGGCCACAGTACTTACTGAGGACTTC
ATATGGTTTTTTTGTTTATTATTATTGAGAAAAGAGCTGAGGTTACCACATTCATTCTTTGTGTTAGAAATGTAGGAGTGTGGTGGTTTT
CTGCAATATTTAGAGCTTAGTCTCATAATTTGGAATTTAAGATAATAAGTAGTAACAAGGCAAGTCTTTTATGTAAGACAGTCAAACAGT
GTCACTTCAGGGACAAAGGCCTGGAAGCCCTTAAAATAAGTTATCTTAGATGTGCCAGAACATATTCAGAGCTTTATTCCTTTAAGCTTA
AGGCTTCAATACTTGTAGAAATGCAAATATTCTTGAGAAATGATACATTTTTTGTTCTCAATTTCTCAATTCTACATACCTGATTATGAG
TGAAGTATCCAAAGCAGGTTTTCATCAGCATGGGGGATGGAAGGTAGGTATAATATGAGGACAATGGAAACTTTGGGAGAAGGGAGTGAG
GAAATGGATAAAGAGAAATTTGAAAATTTTAGGCTGGACTTGAGCACTATTGCTGCTTTCCTATGAACTATCAGAATGTTTAAATGCTTT
ATCATTCATGGTCCACTCTCAACCAACATTTATTATCCTTTAGTAATTAAACAATGGTTTTACATACATTTTTATAATGTAGAAGGAAAT
TCAAGATTCCATAATCGTAAAATTTTTCAGATTTGTCTAATGTGTAATTTGTGCATCTTCACATGCTGCTAAATGCAGATTTAAACATTA
CATCTGAGGATCATGACTTTTCCTCCTTTCTTGGAGATCTTGGTATAAAATTCATCTGCTGTTATAAAATCAGGTTTCTACAGAGTTCGT
TTCACACTAAAGGTAGTTTGTTACTGTTTGCATGAGGAAACCATGTATGTCTCAATCTTTAATTTTAGGTGGTAGTGTTTATTGTTCACC
CTCCCTCTTGCCTCCAAAAGAATGCTGAATTATACGCCAATATTTCCATGTGTATTCTGTTGCCTTGATGCGTACTATACTTGTTGCATG

>1993_1993_13_ADAM22-RUNDC3B_ADAM22_chr7_87607727_ENST00000398209_RUNDC3B_chr7_87445456_ENST00000338056_length(amino acids)=196AA_BP=108
MQAAVAVSVPFLLLCVLGTCPPARCGQAGDASLMELEKRKENRFVERQSIVPLRLIYRSGGEDESRHDALDTRVRGDLGGPQLTHVDQAS
FQVDAFGTSFILDVVLNQKSYQSLDQLSAEVSLSQTSLDPGQSQEGDGKQDTLNVMSEGKEDTPSLLGLCGSLTSVASYKSLTSLKSNDY

--------------------------------------------------------------
>1993_1993_14_ADAM22-RUNDC3B_ADAM22_chr7_87607727_ENST00000398209_RUNDC3B_chr7_87445456_ENST00000394654_length(transcript)=1121nt_BP=369nt
CATGAGGAGCTGAGCGTCTCGGGCGAGGCGGGCTGACGGCAGCACCATGCAGGCGGCAGTGGCTGTGTCCGTGCCCTTCTTGCTGCTCTG
TGTCCTGGGGACCTGCCCTCCGGCGCGCTGCGGCCAGGCAGGAGACGCCTCATTGATGGAGCTAGAGAAGAGGAAGGAAAACCGCTTCGT
GGAGCGCCAGAGCATCGTGCCACTGCGCCTCATCTACCGCTCGGGCGGCGAAGACGAAAGTCGGCACGACGCGCTCGACACGCGGGTGCG
GGGCGACCTCGGTGGCCCGCAGTTGACTCATGTTGACCAAGCAAGCTTCCAGGTTGATGCCTTTGGAACGTCATTCATTCTCGATGTCGT
GCTAAATCAGAAAAGTTATCAAAGTCTTGACCAGTTATCAGCAGAAGTTAGCCTTTCTCAGACTTCACTAGATCCAGGCCAGTCACAAGA
AGGAGATGGAAAACAAGACACATTAAATGTAATGAGTGAAGGTAAGGAAGATACTCCCTCATTACTTGGCCTCTGTGGATCTCTAACGTC
AGTGGCAAGTTACAAGTCTCTAACAAGCTTAAAATCTAATGACTACCTTGCAAGTCCTACAACAGAGATGACAAGTCCAGGCCTAACTCC
ATCCTGAAAATTTTTGTGTAAAAGCCAAAACTTTTTATGTTGTAAATGTTTAATTTACATGTTTGACTGCTGGGAAGACCTTTGAAATTT
TATATTGTTCTGGTACATGTCTGAAATTCTATTGCTTGGAGAGAATCCCCTCCAGATAAGAGATTTTGAGTGAAAAACATAATGATCCTG
CCATTTTTCATTTTTAAAATTCTTACATTTGTCATTGAGAAAGTTCAAAATGGAATAGGCTTTAAAAAAAAAAAAACTTTCAAAGATCCG
CCAAATCATTCATAGCAAATTGTACATATTGTTCAGCTGATTTTTATATATTTAAATACACCTTAGTGGCCAGAGACTGACTTCAAGGTT
TTATTCCAGAGACTCCAGAGACTTAAGCTAAGTATTTTTTCATTCTTTCAGATTTTCAAAAAAAAAAAAAAAAAAAGTTAATTTCATTTT

>1993_1993_14_ADAM22-RUNDC3B_ADAM22_chr7_87607727_ENST00000398209_RUNDC3B_chr7_87445456_ENST00000394654_length(amino acids)=196AA_BP=108
MQAAVAVSVPFLLLCVLGTCPPARCGQAGDASLMELEKRKENRFVERQSIVPLRLIYRSGGEDESRHDALDTRVRGDLGGPQLTHVDQAS
FQVDAFGTSFILDVVLNQKSYQSLDQLSAEVSLSQTSLDPGQSQEGDGKQDTLNVMSEGKEDTPSLLGLCGSLTSVASYKSLTSLKSNDY

--------------------------------------------------------------
>1993_1993_15_ADAM22-RUNDC3B_ADAM22_chr7_87607727_ENST00000398209_RUNDC3B_chr7_87445456_ENST00000493037_length(transcript)=1063nt_BP=369nt
CATGAGGAGCTGAGCGTCTCGGGCGAGGCGGGCTGACGGCAGCACCATGCAGGCGGCAGTGGCTGTGTCCGTGCCCTTCTTGCTGCTCTG
TGTCCTGGGGACCTGCCCTCCGGCGCGCTGCGGCCAGGCAGGAGACGCCTCATTGATGGAGCTAGAGAAGAGGAAGGAAAACCGCTTCGT
GGAGCGCCAGAGCATCGTGCCACTGCGCCTCATCTACCGCTCGGGCGGCGAAGACGAAAGTCGGCACGACGCGCTCGACACGCGGGTGCG
GGGCGACCTCGGTGGCCCGCAGTTGACTCATGTTGACCAAGCAAGCTTCCAGGTTGATGCCTTTGGAACGTCATTCATTCTCGATGTCGT
GCTAAATCAGAAAAGTTATCAAAGTCTTGACCAGTTATCAGCAGAAGTTAGCCTTTCTCAGACTTCACTAGATCCAGGCCAGTCACAAGA
AGGAGATGGAAAACAAGACACATTAAATGTAATGAGTGAAGGTAAGGAAGATACTCCCTCATTACTTGGCCTCTGTGGATCTCTAACGTC
AGTGGCAAGTTACAAGTCTCTAACAAGCTTAAAATCTAATGACTACCTTGCAAGTCCTACAACAGAGATGACAAGTCCAGGCCTAACTCC
ATCCTGAAAATTTTTGTGTAAAAGCCAAAACTTTTTATGTTGTAAATGTTTAATTTACATGTTTGACTGCTGGGAAGACCTTTGAAATTT
TATATTGTTCTGGTACATGTCTGAAATTCTATTGCTTGGAGAGAATCCCCTCCAGATAAGAGATTTTGAGTGAAAAACATAATGATCCTG
CCATTTTTCATTTTTAAAATTCTTACATTTGTCATTGAGAAAGTTCAAAATGGAATAGGCTTTAAAAAAAAAAAAACTTTCAAAGATCCG
CCAAATCATTCATAGCAAATTGTACATATTGTTCAGCTGATTTTTATATATTTAAATACACCTTAGTGGCCAGAGACTGACTTCAAGGTT

>1993_1993_15_ADAM22-RUNDC3B_ADAM22_chr7_87607727_ENST00000398209_RUNDC3B_chr7_87445456_ENST00000493037_length(amino acids)=196AA_BP=108
MQAAVAVSVPFLLLCVLGTCPPARCGQAGDASLMELEKRKENRFVERQSIVPLRLIYRSGGEDESRHDALDTRVRGDLGGPQLTHVDQAS
FQVDAFGTSFILDVVLNQKSYQSLDQLSAEVSLSQTSLDPGQSQEGDGKQDTLNVMSEGKEDTPSLLGLCGSLTSVASYKSLTSLKSNDY

--------------------------------------------------------------
>1993_1993_16_ADAM22-RUNDC3B_ADAM22_chr7_87607727_ENST00000439864_RUNDC3B_chr7_87445456_ENST00000338056_length(transcript)=3072nt_BP=538nt
ACTCGCTCGCTCCCCCCGCCAGCGGAAGCGTCCGCGAAGCACAATGCAGCACTGAGCCGCGGTGGAGGTTGCAGCGCCACGGCCGCCGCA
GCACCGGCCGGGGCTGGGTGGAGGTGGCCGCGGGGACCCCGGGGGCGCGGAGCGAGGGAAACGGACTCGGCGGCGCCGGCATGAGGAGCT
GAGCGTCTCGGGCGAGGCGGGCTGACGGCAGCACCATGCAGGCGGCAGTGGCTGTGTCCGTGCCCTTCTTGCTGCTCTGTGTCCTGGGGA
CCTGCCCTCCGGCGCGCTGCGGCCAGGCAGGAGACGCCTCATTGATGGAGCTAGAGAAGAGGAAGGAAAACCGCTTCGTGGAGCGCCAGA
GCATCGTGCCACTGCGCCTCATCTACCGCTCGGGCGGCGAAGACGAAAGTCGGCACGACGCGCTCGACACGCGGGTGCGGGGCGACCTCG
GTGGCCCGCAGTTGACTCATGTTGACCAAGCAAGCTTCCAGGTTGATGCCTTTGGAACGTCATTCATTCTCGATGTCGTGCTAAATCAGA
AAAGTTATCAAAGTCTTGACCAGTTATCAGCAGAAGTTAGCCTTTCTCAGACTTCACTAGATCCAGGCCAGTCACAAGAAGGAGATGGAA
AACAAGACACATTAAATGTAATGAGTGAAGGTAAGGAAGATACTCCCTCATTACTTGGCCTCTGTGGATCTCTAACGTCAGTGGCAAGTT
ACAAGTCTCTAACAAGCTTAAAATCTAATGACTACCTTGCAAGTCCTACAACAGAGATGACAAGTCCAGGCCTAACTCCATCCTGAAAAT
TTTTGTGTAAAAGCCAAAACTTTTTATGTTGTAAATGTTTAATTTACATGTTTGACTGCTGGGAAGACCTTTGAAATTTTATATTGTTCT
GGTACATGTCTGAAATTCTATTGCTTGGAGAGAATCCCCTCCAGATAAGAGATTTTGAGTGAAAAACATAATGATCCTGCCATTTTTCAT
TTTTAAAATTCTTACATTTGTCATTGAGAAAGTTCAAAATGGAATAGGCTTTAAAAAAAAAAAAACTTTCAAAGATCCGCCAAATCATTC
ATAGCAAATTGTACATATTGTTCAGCTGATTTTTATATATTTAAATACACCTTAGTGGCCAGAGACTGACTTCAAGGTTTTATTCCAGAG
ACTCCAGAGACTTAAGCTAAGTATTTTTTCATTCTTTCAGATTTTCAAAAAAAAAAAAAAAAAAAGTTAATTTCATTTTTTCATTAATGT
CTTCCTAAGTTCTATGCTTTAAATGCCTTGTTTTTAATAACGGGAAAGTTCTCAGCTGCATTTTCACAGTGGCTTATTCAGTTTTTCTTT
AATATTTACCATTTGGTATCAATTCAGCATTCCACTTAACATTTTATAAATTCCATAGGAACATGCCTGTTTTGGTAGTTACTGACTTAA
TTTGTTAGTGCCACAAGGAAAATATTTTACAGTATTTTATGCCATTTAGGCAAAATGAATAAACTGTTTTCCAAGATTTTCTTAAAAGAT
TATCAATTTAAAAGTATGATCAAGTATGCCTCAAAAACTAGAAACATTTCAAAATGTAGAACAAACGTTGAAAAATTGTTTTGCCAGGAA
AGAGTTCAAGTTCAGTTAAGGATTTGAGAGGCTTTTAAACAAGGATCAGTAGGATAGTTATCATATTTACTTAATATATGTCTGATATTC
AGTGCTGGTTCTTTTTCCTGTTTGTGCAACAATGAAGTGTGTCATGTGTGTTTTATAGCCTCTATCATTAATCACACCAGAGTCTCATTT
TAAAACATTTTAATGTTAAAACATCCCCACACTTATACACAGGTAAAATTAGTTTTTTTTTTTTTAAAGTTGTAATCTGTACTTTTTTTT
TTTTGCAATTTTTGAAACAGCTACATTAATCCCTAAAAATCCCACCATACTGAAAATGTATGGCGTGTATTTTCTATAGTAAGTAATATG
AGGAAAACATGATTAGCTGTGCCAAAGAAATTTTATACATTGTTTACATGATGAGGCCACAGTACTTACTGAGGACTTCATATGGTTTTT
TTGTTTATTATTATTGAGAAAAGAGCTGAGGTTACCACATTCATTCTTTGTGTTAGAAATGTAGGAGTGTGGTGGTTTTCTGCAATATTT
AGAGCTTAGTCTCATAATTTGGAATTTAAGATAATAAGTAGTAACAAGGCAAGTCTTTTATGTAAGACAGTCAAACAGTGTCACTTCAGG
GACAAAGGCCTGGAAGCCCTTAAAATAAGTTATCTTAGATGTGCCAGAACATATTCAGAGCTTTATTCCTTTAAGCTTAAGGCTTCAATA
CTTGTAGAAATGCAAATATTCTTGAGAAATGATACATTTTTTGTTCTCAATTTCTCAATTCTACATACCTGATTATGAGTGAAGTATCCA
AAGCAGGTTTTCATCAGCATGGGGGATGGAAGGTAGGTATAATATGAGGACAATGGAAACTTTGGGAGAAGGGAGTGAGGAAATGGATAA
AGAGAAATTTGAAAATTTTAGGCTGGACTTGAGCACTATTGCTGCTTTCCTATGAACTATCAGAATGTTTAAATGCTTTATCATTCATGG
TCCACTCTCAACCAACATTTATTATCCTTTAGTAATTAAACAATGGTTTTACATACATTTTTATAATGTAGAAGGAAATTCAAGATTCCA
TAATCGTAAAATTTTTCAGATTTGTCTAATGTGTAATTTGTGCATCTTCACATGCTGCTAAATGCAGATTTAAACATTACATCTGAGGAT
CATGACTTTTCCTCCTTTCTTGGAGATCTTGGTATAAAATTCATCTGCTGTTATAAAATCAGGTTTCTACAGAGTTCGTTTCACACTAAA
GGTAGTTTGTTACTGTTTGCATGAGGAAACCATGTATGTCTCAATCTTTAATTTTAGGTGGTAGTGTTTATTGTTCACCCTCCCTCTTGC
CTCCAAAAGAATGCTGAATTATACGCCAATATTTCCATGTGTATTCTGTTGCCTTGATGCGTACTATACTTGTTGCATGTATATTAAAAA

>1993_1993_16_ADAM22-RUNDC3B_ADAM22_chr7_87607727_ENST00000439864_RUNDC3B_chr7_87445456_ENST00000338056_length(amino acids)=196AA_BP=108
MQAAVAVSVPFLLLCVLGTCPPARCGQAGDASLMELEKRKENRFVERQSIVPLRLIYRSGGEDESRHDALDTRVRGDLGGPQLTHVDQAS
FQVDAFGTSFILDVVLNQKSYQSLDQLSAEVSLSQTSLDPGQSQEGDGKQDTLNVMSEGKEDTPSLLGLCGSLTSVASYKSLTSLKSNDY

--------------------------------------------------------------
>1993_1993_17_ADAM22-RUNDC3B_ADAM22_chr7_87607727_ENST00000439864_RUNDC3B_chr7_87445456_ENST00000394654_length(transcript)=1290nt_BP=538nt
ACTCGCTCGCTCCCCCCGCCAGCGGAAGCGTCCGCGAAGCACAATGCAGCACTGAGCCGCGGTGGAGGTTGCAGCGCCACGGCCGCCGCA
GCACCGGCCGGGGCTGGGTGGAGGTGGCCGCGGGGACCCCGGGGGCGCGGAGCGAGGGAAACGGACTCGGCGGCGCCGGCATGAGGAGCT
GAGCGTCTCGGGCGAGGCGGGCTGACGGCAGCACCATGCAGGCGGCAGTGGCTGTGTCCGTGCCCTTCTTGCTGCTCTGTGTCCTGGGGA
CCTGCCCTCCGGCGCGCTGCGGCCAGGCAGGAGACGCCTCATTGATGGAGCTAGAGAAGAGGAAGGAAAACCGCTTCGTGGAGCGCCAGA
GCATCGTGCCACTGCGCCTCATCTACCGCTCGGGCGGCGAAGACGAAAGTCGGCACGACGCGCTCGACACGCGGGTGCGGGGCGACCTCG
GTGGCCCGCAGTTGACTCATGTTGACCAAGCAAGCTTCCAGGTTGATGCCTTTGGAACGTCATTCATTCTCGATGTCGTGCTAAATCAGA
AAAGTTATCAAAGTCTTGACCAGTTATCAGCAGAAGTTAGCCTTTCTCAGACTTCACTAGATCCAGGCCAGTCACAAGAAGGAGATGGAA
AACAAGACACATTAAATGTAATGAGTGAAGGTAAGGAAGATACTCCCTCATTACTTGGCCTCTGTGGATCTCTAACGTCAGTGGCAAGTT
ACAAGTCTCTAACAAGCTTAAAATCTAATGACTACCTTGCAAGTCCTACAACAGAGATGACAAGTCCAGGCCTAACTCCATCCTGAAAAT
TTTTGTGTAAAAGCCAAAACTTTTTATGTTGTAAATGTTTAATTTACATGTTTGACTGCTGGGAAGACCTTTGAAATTTTATATTGTTCT
GGTACATGTCTGAAATTCTATTGCTTGGAGAGAATCCCCTCCAGATAAGAGATTTTGAGTGAAAAACATAATGATCCTGCCATTTTTCAT
TTTTAAAATTCTTACATTTGTCATTGAGAAAGTTCAAAATGGAATAGGCTTTAAAAAAAAAAAAACTTTCAAAGATCCGCCAAATCATTC
ATAGCAAATTGTACATATTGTTCAGCTGATTTTTATATATTTAAATACACCTTAGTGGCCAGAGACTGACTTCAAGGTTTTATTCCAGAG
ACTCCAGAGACTTAAGCTAAGTATTTTTTCATTCTTTCAGATTTTCAAAAAAAAAAAAAAAAAAAGTTAATTTCATTTTTTCATTAATGT

>1993_1993_17_ADAM22-RUNDC3B_ADAM22_chr7_87607727_ENST00000439864_RUNDC3B_chr7_87445456_ENST00000394654_length(amino acids)=196AA_BP=108
MQAAVAVSVPFLLLCVLGTCPPARCGQAGDASLMELEKRKENRFVERQSIVPLRLIYRSGGEDESRHDALDTRVRGDLGGPQLTHVDQAS
FQVDAFGTSFILDVVLNQKSYQSLDQLSAEVSLSQTSLDPGQSQEGDGKQDTLNVMSEGKEDTPSLLGLCGSLTSVASYKSLTSLKSNDY

--------------------------------------------------------------
>1993_1993_18_ADAM22-RUNDC3B_ADAM22_chr7_87607727_ENST00000439864_RUNDC3B_chr7_87445456_ENST00000493037_length(transcript)=1232nt_BP=538nt
ACTCGCTCGCTCCCCCCGCCAGCGGAAGCGTCCGCGAAGCACAATGCAGCACTGAGCCGCGGTGGAGGTTGCAGCGCCACGGCCGCCGCA
GCACCGGCCGGGGCTGGGTGGAGGTGGCCGCGGGGACCCCGGGGGCGCGGAGCGAGGGAAACGGACTCGGCGGCGCCGGCATGAGGAGCT
GAGCGTCTCGGGCGAGGCGGGCTGACGGCAGCACCATGCAGGCGGCAGTGGCTGTGTCCGTGCCCTTCTTGCTGCTCTGTGTCCTGGGGA
CCTGCCCTCCGGCGCGCTGCGGCCAGGCAGGAGACGCCTCATTGATGGAGCTAGAGAAGAGGAAGGAAAACCGCTTCGTGGAGCGCCAGA
GCATCGTGCCACTGCGCCTCATCTACCGCTCGGGCGGCGAAGACGAAAGTCGGCACGACGCGCTCGACACGCGGGTGCGGGGCGACCTCG
GTGGCCCGCAGTTGACTCATGTTGACCAAGCAAGCTTCCAGGTTGATGCCTTTGGAACGTCATTCATTCTCGATGTCGTGCTAAATCAGA
AAAGTTATCAAAGTCTTGACCAGTTATCAGCAGAAGTTAGCCTTTCTCAGACTTCACTAGATCCAGGCCAGTCACAAGAAGGAGATGGAA
AACAAGACACATTAAATGTAATGAGTGAAGGTAAGGAAGATACTCCCTCATTACTTGGCCTCTGTGGATCTCTAACGTCAGTGGCAAGTT
ACAAGTCTCTAACAAGCTTAAAATCTAATGACTACCTTGCAAGTCCTACAACAGAGATGACAAGTCCAGGCCTAACTCCATCCTGAAAAT
TTTTGTGTAAAAGCCAAAACTTTTTATGTTGTAAATGTTTAATTTACATGTTTGACTGCTGGGAAGACCTTTGAAATTTTATATTGTTCT
GGTACATGTCTGAAATTCTATTGCTTGGAGAGAATCCCCTCCAGATAAGAGATTTTGAGTGAAAAACATAATGATCCTGCCATTTTTCAT
TTTTAAAATTCTTACATTTGTCATTGAGAAAGTTCAAAATGGAATAGGCTTTAAAAAAAAAAAAACTTTCAAAGATCCGCCAAATCATTC
ATAGCAAATTGTACATATTGTTCAGCTGATTTTTATATATTTAAATACACCTTAGTGGCCAGAGACTGACTTCAAGGTTTTATTCCAGAG

>1993_1993_18_ADAM22-RUNDC3B_ADAM22_chr7_87607727_ENST00000439864_RUNDC3B_chr7_87445456_ENST00000493037_length(amino acids)=196AA_BP=108
MQAAVAVSVPFLLLCVLGTCPPARCGQAGDASLMELEKRKENRFVERQSIVPLRLIYRSGGEDESRHDALDTRVRGDLGGPQLTHVDQAS
FQVDAFGTSFILDVVLNQKSYQSLDQLSAEVSLSQTSLDPGQSQEGDGKQDTLNVMSEGKEDTPSLLGLCGSLTSVASYKSLTSLKSNDY

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ADAM22-RUNDC3B

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

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Related Drugs for ADAM22-RUNDC3B

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for ADAM22-RUNDC3B

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner	Gene	Disease ID	Disease name	# pubmeds	Source
Hgene	ADAM22	C4693688	EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 61	2	GENOMICS_ENGLAND;UNIPROT

Fusion Gene Studies in Kim Lab

Fusion gene:ADAM22-RUNDC3B (FusionGDB2 ID:HG53616TG154661)

Fusion Gene Summary for ADAM22-RUNDC3B

Fusion Gene ORF analysis for ADAM22-RUNDC3B

Fusion Genomic Features for ADAM22-RUNDC3B

Fusion Protein Features for ADAM22-RUNDC3B

Fusion Gene Sequence for ADAM22-RUNDC3B

Fusion Gene PPI Analysis for ADAM22-RUNDC3B

Related Drugs for ADAM22-RUNDC3B

Related Diseases for ADAM22-RUNDC3B

Fusion Gene Studies
in Kim Lab