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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:EGLN1-PTPRF (FusionGDB2 ID:HG54583TG5792)

Fusion Gene Summary for EGLN1-PTPRF

check button Fusion gene summary
Fusion gene informationFusion gene name: EGLN1-PTPRF
Fusion gene ID: hg54583tg5792
HgeneTgene
Gene symbol

EGLN1

PTPRF

Gene ID

54583

5792

Gene nameegl-9 family hypoxia inducible factor 1protein tyrosine phosphatase receptor type F
SynonymsC1orf12|ECYT3|HALAH|HIF-PH2|HIFPH2|HPH-2|HPH2|PHD2|SM20|ZMYND6BNAH2|LAR
Cytomap('EGLN1')('PTPRF')

1q42.2

1p34.2

Type of geneprotein-codingprotein-coding
Descriptionegl nine homolog 1HIF-prolyl hydroxylase 2egl nine-like protein 1hypoxia-inducible factor prolyl hydroxylase 2prolyl hydroxylase domain-containing protein 2zinc finger MYND domain-containing protein 6receptor-type tyrosine-protein phosphatase FLCA-homologleukocyte antigen-related (LAR) PTP receptorleukocyte antigen-related tyrosine phosphataseleukocyte common antigen relatedprotein tyrosine phosphatase, receptor type, F polypeptidereceptor-linke
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000366641, ENST00000476717, 
Fusion gene scores* DoF score4 X 2 X 4=3210 X 14 X 6=840
# samples 415
** MAII scorelog2(4/32*10)=0.321928094887362
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(15/840*10)=-2.48542682717024
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: EGLN1 [Title/Abstract] AND PTPRF [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointEGLN1(231556744)-PTPRF(44083116), # samples:3
Anticipated loss of major functional domain due to fusion event.EGLN1-PTPRF seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
EGLN1-PTPRF seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
EGLN1-PTPRF seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
EGLN1-PTPRF seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneEGLN1

GO:0001666

response to hypoxia

16956324

HgeneEGLN1

GO:0018401

peptidyl-proline hydroxylation to 4-hydroxy-L-proline

11598268

HgeneEGLN1

GO:0032364

oxygen homeostasis

16956324

HgeneEGLN1

GO:0043433

negative regulation of DNA-binding transcription factor activity

16956324

HgeneEGLN1

GO:0071731

response to nitric oxide

21601578

TgenePTPRF

GO:0099560

synaptic membrane adhesion

26321637


check buttonFusion gene breakpoints across EGLN1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across PTPRF (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUSCTCGA-43-8115-01AEGLN1chr1

231556744

-PTPRFchr1

44083116

+
ChimerDB4LUSCTCGA-43-8115EGLN1chr1

231556744

-PTPRFchr1

44083116

+


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Fusion Gene ORF analysis for EGLN1-PTPRF

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000366641ENST00000496447EGLN1chr1

231556744

-PTPRFchr1

44083116

+
In-frameENST00000366641ENST00000359947EGLN1chr1

231556744

-PTPRFchr1

44083116

+
In-frameENST00000366641ENST00000372413EGLN1chr1

231556744

-PTPRFchr1

44083116

+
In-frameENST00000366641ENST00000372414EGLN1chr1

231556744

-PTPRFchr1

44083116

+
In-frameENST00000366641ENST00000422171EGLN1chr1

231556744

-PTPRFchr1

44083116

+
In-frameENST00000366641ENST00000438120EGLN1chr1

231556744

-PTPRFchr1

44083116

+
intron-3CDSENST00000476717ENST00000359947EGLN1chr1

231556744

-PTPRFchr1

44083116

+
intron-3CDSENST00000476717ENST00000372413EGLN1chr1

231556744

-PTPRFchr1

44083116

+
intron-3CDSENST00000476717ENST00000372414EGLN1chr1

231556744

-PTPRFchr1

44083116

+
intron-3CDSENST00000476717ENST00000422171EGLN1chr1

231556744

-PTPRFchr1

44083116

+
intron-3CDSENST00000476717ENST00000438120EGLN1chr1

231556744

-PTPRFchr1

44083116

+
intron-3UTRENST00000476717ENST00000496447EGLN1chr1

231556744

-PTPRFchr1

44083116

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000366641EGLN1chr1231556744-ENST00000359947PTPRFchr144083116+7363404731565699847
ENST00000366641EGLN1chr1231556744-ENST00000438120PTPRFchr144083116+6054404731565699847
ENST00000366641EGLN1chr1231556744-ENST00000372413PTPRFchr144083116+7369404731565699847
ENST00000366641EGLN1chr1231556744-ENST00000372414PTPRFchr144083116+7369404731565699847
ENST00000366641EGLN1chr1231556744-ENST00000422171PTPRFchr144083116+6539404731565699847

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000366641ENST00000359947EGLN1chr1231556744-PTPRFchr144083116+0.0094535190.99054646
ENST00000366641ENST00000438120EGLN1chr1231556744-PTPRFchr144083116+0.0117691110.98823094
ENST00000366641ENST00000372413EGLN1chr1231556744-PTPRFchr144083116+0.0094590620.9905409
ENST00000366641ENST00000372414EGLN1chr1231556744-PTPRFchr144083116+0.0094590620.9905409
ENST00000366641ENST00000422171EGLN1chr1231556744-PTPRFchr144083116+0.0111109180.9888891

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Fusion Genomic Features for EGLN1-PTPRF


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
EGLN1chr1231556743-PTPRFchr144083115+7.30E-121
EGLN1chr1231556743-PTPRFchr144083115+7.30E-121
EGLN1chr1231556743-PTPRFchr144083115+7.30E-121
EGLN1chr1231556743-PTPRFchr144083115+7.30E-121

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for EGLN1-PTPRF


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr1:231556744/chr1:44083116)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneEGLN1chr1:231556744chr1:44083116ENST00000366641-15241_251297427.0RegionBeta(2)beta(3) 'finger-like' loop
HgeneEGLN1chr1:231556744chr1:44083116ENST00000366641-156_20297427.0RegionNote=Required for nuclear export
HgeneEGLN1chr1:231556744chr1:44083116ENST00000366641-1521_58297427.0Zinc fingerMYND-type
TgenePTPRFchr1:231556744chr1:44083116ENST0000035994722341639_189813571908.0DomainTyrosine-protein phosphatase 2
TgenePTPRFchr1:231556744chr1:44083116ENST0000037241319311352_160713481899.0DomainTyrosine-protein phosphatase 1
TgenePTPRFchr1:231556744chr1:44083116ENST0000037241319311639_189813481899.0DomainTyrosine-protein phosphatase 2
TgenePTPRFchr1:231556744chr1:44083116ENST0000037241420321639_189813571908.0DomainTyrosine-protein phosphatase 2
TgenePTPRFchr1:231556744chr1:44083116ENST0000043812021331352_160713481899.0DomainTyrosine-protein phosphatase 1
TgenePTPRFchr1:231556744chr1:44083116ENST0000043812021331639_189813481899.0DomainTyrosine-protein phosphatase 2
TgenePTPRFchr1:231556744chr1:44083116ENST0000035994722341548_155413571908.0RegionSubstrate binding
TgenePTPRFchr1:231556744chr1:44083116ENST0000037241319311548_155413481899.0RegionSubstrate binding
TgenePTPRFchr1:231556744chr1:44083116ENST0000037241420321548_155413571908.0RegionSubstrate binding
TgenePTPRFchr1:231556744chr1:44083116ENST0000043812021331548_155413481899.0RegionSubstrate binding

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneEGLN1chr1:231556744chr1:44083116ENST00000366641-15291_392297427.0DomainFe2OG dioxygenase
TgenePTPRFchr1:231556744chr1:44083116ENST0000035994722341014_109813571908.0DomainFibronectin type-III 8
TgenePTPRFchr1:231556744chr1:44083116ENST0000035994722341352_160713571908.0DomainTyrosine-protein phosphatase 1
TgenePTPRFchr1:231556744chr1:44083116ENST000003599472234135_22413571908.0DomainNote=Ig-like C2-type 2
TgenePTPRFchr1:231556744chr1:44083116ENST000003599472234232_31413571908.0DomainNote=Ig-like C2-type 3
TgenePTPRFchr1:231556744chr1:44083116ENST000003599472234321_41113571908.0DomainFibronectin type-III 1
TgenePTPRFchr1:231556744chr1:44083116ENST00000359947223433_12313571908.0DomainNote=Ig-like C2-type 1
TgenePTPRFchr1:231556744chr1:44083116ENST000003599472234416_51013571908.0DomainFibronectin type-III 2
TgenePTPRFchr1:231556744chr1:44083116ENST000003599472234514_60413571908.0DomainFibronectin type-III 3
TgenePTPRFchr1:231556744chr1:44083116ENST000003599472234609_70613571908.0DomainFibronectin type-III 4
TgenePTPRFchr1:231556744chr1:44083116ENST000003599472234711_81913571908.0DomainFibronectin type-III 5
TgenePTPRFchr1:231556744chr1:44083116ENST000003599472234820_91413571908.0DomainFibronectin type-III 6
TgenePTPRFchr1:231556744chr1:44083116ENST000003599472234918_101013571908.0DomainFibronectin type-III 7
TgenePTPRFchr1:231556744chr1:44083116ENST0000037241319311014_109813481899.0DomainFibronectin type-III 8
TgenePTPRFchr1:231556744chr1:44083116ENST000003724131931135_22413481899.0DomainNote=Ig-like C2-type 2
TgenePTPRFchr1:231556744chr1:44083116ENST000003724131931232_31413481899.0DomainNote=Ig-like C2-type 3
TgenePTPRFchr1:231556744chr1:44083116ENST000003724131931321_41113481899.0DomainFibronectin type-III 1
TgenePTPRFchr1:231556744chr1:44083116ENST00000372413193133_12313481899.0DomainNote=Ig-like C2-type 1
TgenePTPRFchr1:231556744chr1:44083116ENST000003724131931416_51013481899.0DomainFibronectin type-III 2
TgenePTPRFchr1:231556744chr1:44083116ENST000003724131931514_60413481899.0DomainFibronectin type-III 3
TgenePTPRFchr1:231556744chr1:44083116ENST000003724131931609_70613481899.0DomainFibronectin type-III 4
TgenePTPRFchr1:231556744chr1:44083116ENST000003724131931711_81913481899.0DomainFibronectin type-III 5
TgenePTPRFchr1:231556744chr1:44083116ENST000003724131931820_91413481899.0DomainFibronectin type-III 6
TgenePTPRFchr1:231556744chr1:44083116ENST000003724131931918_101013481899.0DomainFibronectin type-III 7
TgenePTPRFchr1:231556744chr1:44083116ENST0000037241420321014_109813571908.0DomainFibronectin type-III 8
TgenePTPRFchr1:231556744chr1:44083116ENST0000037241420321352_160713571908.0DomainTyrosine-protein phosphatase 1
TgenePTPRFchr1:231556744chr1:44083116ENST000003724142032135_22413571908.0DomainNote=Ig-like C2-type 2
TgenePTPRFchr1:231556744chr1:44083116ENST000003724142032232_31413571908.0DomainNote=Ig-like C2-type 3
TgenePTPRFchr1:231556744chr1:44083116ENST000003724142032321_41113571908.0DomainFibronectin type-III 1
TgenePTPRFchr1:231556744chr1:44083116ENST00000372414203233_12313571908.0DomainNote=Ig-like C2-type 1
TgenePTPRFchr1:231556744chr1:44083116ENST000003724142032416_51013571908.0DomainFibronectin type-III 2
TgenePTPRFchr1:231556744chr1:44083116ENST000003724142032514_60413571908.0DomainFibronectin type-III 3
TgenePTPRFchr1:231556744chr1:44083116ENST000003724142032609_70613571908.0DomainFibronectin type-III 4
TgenePTPRFchr1:231556744chr1:44083116ENST000003724142032711_81913571908.0DomainFibronectin type-III 5
TgenePTPRFchr1:231556744chr1:44083116ENST000003724142032820_91413571908.0DomainFibronectin type-III 6
TgenePTPRFchr1:231556744chr1:44083116ENST000003724142032918_101013571908.0DomainFibronectin type-III 7
TgenePTPRFchr1:231556744chr1:44083116ENST0000043812021331014_109813481899.0DomainFibronectin type-III 8
TgenePTPRFchr1:231556744chr1:44083116ENST000004381202133135_22413481899.0DomainNote=Ig-like C2-type 2
TgenePTPRFchr1:231556744chr1:44083116ENST000004381202133232_31413481899.0DomainNote=Ig-like C2-type 3
TgenePTPRFchr1:231556744chr1:44083116ENST000004381202133321_41113481899.0DomainFibronectin type-III 1
TgenePTPRFchr1:231556744chr1:44083116ENST00000438120213333_12313481899.0DomainNote=Ig-like C2-type 1
TgenePTPRFchr1:231556744chr1:44083116ENST000004381202133416_51013481899.0DomainFibronectin type-III 2
TgenePTPRFchr1:231556744chr1:44083116ENST000004381202133514_60413481899.0DomainFibronectin type-III 3
TgenePTPRFchr1:231556744chr1:44083116ENST000004381202133609_70613481899.0DomainFibronectin type-III 4
TgenePTPRFchr1:231556744chr1:44083116ENST000004381202133711_81913481899.0DomainFibronectin type-III 5
TgenePTPRFchr1:231556744chr1:44083116ENST000004381202133820_91413481899.0DomainFibronectin type-III 6
TgenePTPRFchr1:231556744chr1:44083116ENST000004381202133918_101013481899.0DomainFibronectin type-III 7
TgenePTPRFchr1:231556744chr1:44083116ENST00000359947223468_7713571908.0RegionHeparin-binding
TgenePTPRFchr1:231556744chr1:44083116ENST00000372413193168_7713481899.0RegionHeparin-binding
TgenePTPRFchr1:231556744chr1:44083116ENST00000372414203268_7713571908.0RegionHeparin-binding
TgenePTPRFchr1:231556744chr1:44083116ENST00000438120213368_7713481899.0RegionHeparin-binding
TgenePTPRFchr1:231556744chr1:44083116ENST0000035994722341285_190713571908.0Topological domainCytoplasmic
TgenePTPRFchr1:231556744chr1:44083116ENST00000359947223430_126313571908.0Topological domainExtracellular
TgenePTPRFchr1:231556744chr1:44083116ENST0000037241319311285_190713481899.0Topological domainCytoplasmic
TgenePTPRFchr1:231556744chr1:44083116ENST00000372413193130_126313481899.0Topological domainExtracellular
TgenePTPRFchr1:231556744chr1:44083116ENST0000037241420321285_190713571908.0Topological domainCytoplasmic
TgenePTPRFchr1:231556744chr1:44083116ENST00000372414203230_126313571908.0Topological domainExtracellular
TgenePTPRFchr1:231556744chr1:44083116ENST0000043812021331285_190713481899.0Topological domainCytoplasmic
TgenePTPRFchr1:231556744chr1:44083116ENST00000438120213330_126313481899.0Topological domainExtracellular
TgenePTPRFchr1:231556744chr1:44083116ENST0000035994722341264_128413571908.0TransmembraneHelical
TgenePTPRFchr1:231556744chr1:44083116ENST0000037241319311264_128413481899.0TransmembraneHelical
TgenePTPRFchr1:231556744chr1:44083116ENST0000037241420321264_128413571908.0TransmembraneHelical
TgenePTPRFchr1:231556744chr1:44083116ENST0000043812021331264_128413481899.0TransmembraneHelical


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Fusion Gene Sequence for EGLN1-PTPRF


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>25493_25493_1_EGLN1-PTPRF_EGLN1_chr1_231556744_ENST00000366641_PTPRF_chr1_44083116_ENST00000359947_length(transcript)=7363nt_BP=4047nt
TTAGGGGCAGAAAAACATTTGTAATAATTAATGGCTTTGAGAGACACAAGGCTTTGTTTGCCCCAGAGTATTAGTTAACCCACCTAGTGC
TCCTAATCATACAATATTAAGGATTGGGAGGGACATTCATTGCCTCACTCTCTATTTGTTTCACCTTCTGTAAAATTGGTAGAATAATAG
TACCCACTTCATAGCATTGTATGATGATTAAATTGGTTAATATTTTTAAAATGCTTAGAACACAGATTGGGCACATAACAGCAAGCACCA
CATGTGTTTATAAGATAAATTCCTTTGTGTTGCCTTCCGTTAAAGTTTAAATAAGTAAATAAATAAATAAATACTTGCATGACATTTTGA
AGTCTCTCTATAACATCTGAGTAAGTGGCGGCTGCGACAATGCTACTGGAGTTCCAGAATCGTGTTGGTGACAAGATTGTTCACCAGCAT
ATGGTGTGGTGAAAACTCACTAATTTGGAATTAGTTCAGATTATTAAGCCTGAATAGGTGAAAATCCTGAAATCAAGGATCTTTGGAACT
ATTTGAAATCAGTATTTTATATTTTCCTGTTGTATTCATTAAAGTGTTGCAAGTGTTCTATTTGATGGATTAAGTATATTTAGGATATAC
ATGTTCAATTTGTGATTTTGTATACTTAATTGGAACAAGAAAGCTAATAAAGGTTTTGATATGGACATCTATTCTTTTAAGTAAACTTCA
ATGAAAATATATGAGTAGAGCATATAGAGATGTAAATAATTTGTGGACACACCACAGACTGAAATAGCAAATTTAAAAGAAATTGTTGGA
AGAATCAAGTGTTTGTGGAATGAGTCCTCCTAGTAAAGTTCCTGCTCTTGTGAATAATTAAGCCTCATGTATAATTACTATAGCAAAAGG
AAGCCTAAGAAGTATTAGACTCTACTTGTATTTAAATTACATTTTACATAATTTATGTGTATGAAAAATGTTTTAAATGCTTATTTTCGT
AAGCCATGAGATAGCTCCTTTATATTTTAAGAATTTCTGAATTAATTTGCTTGGATTTTATTAGTGCAAATGGCAGAGCTAGCAATTCCT
TTTTCTGTGTTCCCATTCCATCCTATTCATCCCTCTTTTAGGAAACTCTGAACTCTGGATTGTCCTTGTTTACATACCTGCCTCCTGCAT
TGGACTATGTGTCTCTGAGTGTAGTATGACTAATTCATTTGTTTGTCAAGGACTCTCAATGCATTTGTTGAACAGCCTAATTAGTAATGT
CTGCAACAATGACATTTTACTGTATTTAATAAAGCTCTGGGAAAGTAGGATACACATAAGACAGGTCTAGGTCTAAATTCTTTACAGAAA
CTTGGATTTTTAGTTCGGTTTGAAATTTGAAGATGTGAGTATATTTATCTCAGTTTCCCAAAGGACAAGCTAATTGGAATTATCATCCTC
TTTCACTTGATTGGATCCCCAGAATGCCATTTACGCATGCAGCAGGATTTTATAACAGTTTTAAATTCTGTATATTTGATGAAGAGGTTT
TATATTTTTGGATTCAAGCCTCTTTTTAAACTTCTACAATATGGTTTACAATAATTCCTTATATCCTGCTTTTGAAATACATATTACAAC
TTTTTAAGTTTGGAAGGCTATATTTCAAGGACTGAAGTTACAGTATACTCAAGTGATACACAAGCCTAGCACCCCACTTTCCACATAGTG
TTCGATAAAGATTGATAAACTCGAAATCACAGACCTTTTAATTCTTAAGACAAATAGCAGCAGAAAGAAACATCTTTGGCTTATTTCTGG
TAAGGTTTTTATGCTCTGTAAAACAAAGAATTGTATTCATCCGCGCAGCACAGATTCTATTAAAAATAAATGTGAGAGTCGTTAATGTAG
TACTGCTCATTTACCATCAAAATTCACTTTTCAGGAATAATCCCATCAGTTTAAATTGGATATTGGAATGAGCATTGATTACATTTAACT
TGGTAGCCCAAAATTTCTTCATGGGGTTTTGAACTCGGCGGGATTTCAAAGGTTTTAAAAATGAGTTTTTGATTTTTTTTAAAACCCTCA
AATTTCATTACCTTTAAACTAGGTCGAAACGGGGCGCAAGAGATTGGATTAACACCATAGTAATACTTATTTTGTTCTTAACCATTTCAG
GGCTTCTTGAAATAGAGGCTGTATGGTGTAATGGAAAAAACAGCCTTGGAATCTGGGAGCCTGATTCCTGGATTCAGTCCCAGTTTTGCG
TGACCTTGGGCAAGTTACTTTACTTCTCTGAATTTCCGTTTCCTCCTCTGCAAAATGAGGATCGCAATAGCCACCTTGCAACCTTGACTG
GAGCGAGCCTCGCACACCCCGCGCCGGCCTGGAGGAAGAGCAGCCATGATTACGCCGCCTTCGCTCCGCTACCCGCTTGCGGCTGGCGCC
CTCCTCCAGCAGGTGTAGGCGCTGCCGCGCTGCCCCACGCCTTTCCGCCGCTCGCGGGCCTGCGCCTCGGCGTCCCCGAGGAGGCCGCTG
CGGGCTGAGGTAGCGCACCGGCCTCTCGGCGTCCCAGTCCGGTCCCGGGCGGAGGGAAAGCGGGCGACCCACCTCCGAGGCAGAAGCCGA
GGCCCGGCCCCGCCGAGTGCGGAGGAGCGCAGGCAGCCCCCGCCCCTCGGCCCTCCCCCCGGCCCTCCCGGCCCTCCCTCCGCCCCCTCC
GCCCTCGCGCGCCGCCCGCCCGGGTCGCCGCGGGGCCGTGGTGTACGTGCAGAGCGCGCAGAGCGAGTGGCGCCCGTATGCCCTGCGCTC
CTCCACAGCCTGGGCCGGGCCGCCCGGGACGCTGAGGCGGCGGCGGCGGCCGAGGGGGCCGGTCTTGCGCTCCCCAGGCCCGCGCGCCTG
AGCCCAGGTTGCCATTCGCCGCACAGGCCCTATTCTCTCAGCCCTCGGCGGCGATGAGGCGCTGAGGCGGCTGCCGGCGCTGCGCCGGAG
CTTAGGACTCGGAAGCGGCCGGGCCGAGGGCGTGGGGTGCCGGCCTCCCTGAGGCGAGGGTAGCGGGTGCATGGCGCAGTAACGGCCCCT
ATCTCTCTCCCCGCTCCCCAGCCTCGGGCGAGGCCGTCCGGCCGCTACCCCTCCTGCTCGGCCGCCGCAGTCGCCGTCGCCGCCGCCGCC
GCCGCCATGGCCAATGACAGCGGCGGGCCCGGCGGGCCGAGCCCGAGCGAGCGAGACCGGCAGTACTGCGAGCTGTGCGGGAAGATGGAG
AACCTGCTGCGCTGCAGCCGCTGCCGCAGCTCCTTCTACTGCTGCAAGGAGCACCAGCGTCAGGACTGGAAGAAGCACAAGCTCGTGTGC
CAGGGCAGCGAGGGCGCCCTCGGCCACGGAGTGGGCCCACACCAGCATTCCGGCCCCGCGCCGCCGGCTGCAGTGCCGCCGCCCAGGGCC
GGGGCCCGGGAGCCCAGGAAGGCAGCGGCGCGCCGGGACAACGCCTCCGGGGACGCGGCCAAGGGAAAAGTAAAGGCCAAGCCCCCGGCC
GACCCAGCGGCGGCCGCGTCGCCGTGTCGTGCGGCCGCCGGCGGCCAGGGCTCGGCGGTGGCTGCCGAAGCCGAGCCCGGCAAGGAGGAG
CCGCCGGCCCGCTCATCGCTGTTCCAGGAGAAGGCGAACCTGTACCCCCCAAGCAACACGCCCGGGGATGCGCTGAGCCCCGGCGGCGGC
CTGCGGCCCAACGGGCAGACGAAGCCCCTGCCGGCGCTGAAGCTGGCGCTCGAGTACATCGTGCCGTGCATGAACAAGCACGGCATCTGT
GTGGTGGACGACTTCCTCGGCAAGGAGACCGGACAGCAGATCGGCGACGAGGTGCGCGCCCTGCACGACACCGGGAAGTTCACGGACGGG
CAGCTGGTCAGCCAGAAGAGTGACTCGTCCAAGGACATCCGAGGCGATAAGATCACCTGGATCGAGGGCAAGGAGCCCGGCTGCGAAACC
ATTGGGCTGCTCATGAGCAGCATGGACGACCTGATACGCCACTGTAACGGGAAGCTGGGCAGCTACAAAATCAATGGCCGGACGAAATCC
ATCGACCCTGGACAGCAGTTCACGTGGGAGAATTCAAACCTGGAGGTGAACAAGCCCAAGAACCGCTATGCGAATGTCATCGCCTACGAC
CACTCTCGAGTCATCCTTACCTCTATCGATGGCGTCCCCGGGAGTGACTACATCAATGCCAACTACATCGATGGCTACCGCAAGCAGAAT
GCCTACATCGCCACGCAGGGCCCCCTGCCCGAGACCATGGGTGATTTCTGGAGGATGGTGTGGGAACAGCGCACGGCCACTGTGGTCATG
ATGACACGGCTGGAGGAGAAGTCCCGGGTAAAATGTGATCAGTACTGGCCAGCCCGTGGCACCGAGACCTGTGGCCTTATTCAGGTGACC
CTGTTGGACACAGTGGAGCTGGCCACATACACTGTGCGCACCTTCGCACTCCACAAGAGTGGCTCCAGTGAGAAGCGCGAGCTGCGTCAG
TTTCAGTTCATGGCCTGGCCAGACCATGGAGTTCCTGAGTACCCAACTCCCATCCTGGCCTTCCTACGACGGGTCAAGGCCTGCAACCCC
CTAGACGCAGGGCCCATGGTGGTGCACTGCAGCGCGGGCGTGGGCCGCACCGGCTGCTTCATCGTGATTGATGCCATGTTGGAGCGGATG
AAGCACGAGAAGACGGTGGACATCTATGGCCACGTGACCTGCATGCGATCACAGAGGAACTACATGGTGCAGACGGAGGACCAGTACGTG
TTCATCCATGAGGCGCTGCTGGAGGCTGCCACGTGCGGCCACACAGAGGTGCCTGCCCGCAACCTGTATGCCCACATCCAGAAGCTGGGC
CAAGTGCCTCCAGGGGAGAGTGTGACCGCCATGGAGCTCGAGTTCAAGTTGCTGGCCAGCTCCAAGGCCCACACGTCCCGCTTCATCAGC
GCCAACCTGCCCTGCAACAAGTTCAAGAACCGGCTGGTGAACATCATGCCCTACGAATTGACCCGTGTGTGTCTGCAGCCCATCCGTGGT
GTGGAGGGCTCTGACTACATCAATGCCAGCTTCCTGGATGGTTATAGACAGCAGAAGGCCTACATAGCTACACAGGGGCCTCTGGCAGAG
AGCACCGAGGACTTCTGGCGCATGCTATGGGAGCACAATTCCACCATCATCGTCATGCTGACCAAGCTTCGGGAGATGGGCAGGGAGAAA
TGCCACCAGTACTGGCCAGCAGAGCGCTCTGCTCGCTACCAGTACTTTGTTGTTGACCCGATGGCTGAGTACAACATGCCCCAGTATATC
CTGCGTGAGTTCAAGGTCACGGATGCCCGGGATGGGCAGTCAAGGACAATCCGGCAGTTCCAGTTCACAGACTGGCCAGAGCAGGGCGTG
CCCAAGACAGGCGAGGGATTCATTGACTTCATCGGGCAGGTGCATAAGACCAAGGAGCAGTTTGGACAGGATGGGCCTATCACGGTGCAC
TGCAGTGCTGGCGTGGGCCGCACCGGGGTGTTCATCACTCTGAGCATCGTCCTGGAGCGCATGCGCTACGAGGGCGTGGTCGACATGTTT
CAGACCGTGAAGACCCTGCGTACACAGCGTCCTGCCATGGTGCAGACAGAGGACCAGTATCAGCTGTGCTACCGTGCGGCCCTGGAGTAC
CTCGGCAGCTTTGACCACTATGCAACGTAACTACCGCTCCCCTCTCCTCCGCCACCCCCGCCGTGGGGCTCCGGAGGGGACCCAGCTCCT
CTGAGCCATACCGACCATCGTCCAGCCCTCCTACGCAGATGCTGTCACTGGCAGAGCACAGCCCACGGGGATCACAGCGTTTCAGGAACG
TTGCCACACCAATCAGAGAGCCTAGAACATCCCTGGGCAAGTGGATGGCCCAGCAGGCAGGCACTGTGGCCCTTCTGTCCACCAGACCCA
CCTGGAGCCCGCTTCAAGCTCTCTGTTGCGCTCCCGCATTTCTCATGCTTCTTCTCATGGGGTGGGGTTGGGGCAAAGCCTCCTTTTTAA
TACATTAAGTGGGGTAGACTGAGGGATTTTAGCCTCTTCCCTCTGATTTTTCCTTTCGCGAATCCGTATCTGCAGAATGGGCCACTGTAG
GGGTTGGGGTTTATTTTGTTTTGTTTTTTTTTTTCTTGAGTTCACTTTGGATCCTTATTTTGTATGACTTCTGCTGAAGGACAGAACATT
GCCTTCCTCGTGCAGAGCTGGGGCTGCCAGCCTGAGCGGAGGCTCGGCCGTGGGCCGGGAGGCAGTGCTGATCCGGCTGCTCCTCCAGCC
CTTCAGACGAGATCCTGTTTCAGCTAAATGCAGGGAAACTCAATGTTTTTTTAAGTTTTGTTTTCCCTTTAAAGCCTTTTTTTAGGCCAC
ATTGACAGTGGTGGGCGGGGAGAAGATAGGGAACACTCATCCCTGGTCGTCTATCCCAGTGTGTGTTTAACATTCACAGCCCAGAACCAC
AGATGTGTCTGGGAGAGCCTGGCAAGGCATTCCTCATCACCATCGTGTTTGCAAAGGTTAAAACAAAAACAAAAAACCACAAAAATAAAA
AACAAAAAAAACAAAAAACCCAAGAAAAAAAAAAAGAGTCAGCCCTTGGCTTCTGCTTCAAACCCTCAAGAGGGGAAGCAACTCCGTGTG
CCTGGGGTTCCCGAGGGAGCTGCTGGCTGACCTGGGCCCACAGAGCCTGGCTTTGGTCCCCAGCATTGCAGTATGGTGTGGTGTTTGTAG
GCTGTGGGGTCTGGCTGTGTGGCCAAGGTGAATAGCACAGGTTAGGGTGTGTGCCACACCCCATGCACCTCAGGGCCAAGCGGGGGCGTG
GCTGGCCTTTCAGGTCCAGGCCAGTGGGCCTGGTAGCACATGTCTGTCCTCAGAGCAGGGGCCAGATGATTTTCCTCCCTGGTTTGCAGC
TGTTTTCAAAGCCCCCGATAATCGCTCTTTTCCACTCCAAGATGCCCTCATAAACCAATGTGGCAAGACTACTGGACTTCTATCAATGGT
ACTCTAATCAGTCCTTATTATCCCAGCTTGCTGAGGGGCAGGGAGAGCGCCTCTTCCTCTGGGCAGCGCTATCTAGATAGGTAAGTGGGG
GCGGGGAAGGGTGCATAGCTGTTTTAGCTGAGGGACGTGGTGCCGACGTCCCCAAACCTAGCTAGGCTAAGTCAAGATCAACATTCCAGG
GTTGGTAATGTTGGATGATGAAACATTCATTTTTACCTTGTGGATGCTAGTGCTGTAGAGTTCACTGTTGTACACAGTCTGTTTTCTATT
TGTTAAGAAAAACTACAGCATCATTGCATAATTCTTGATGGTAATAAATTTGAATAATCAGATTTCTTACAAA

>25493_25493_1_EGLN1-PTPRF_EGLN1_chr1_231556744_ENST00000366641_PTPRF_chr1_44083116_ENST00000359947_length(amino acids)=847AA_BP=297
MANDSGGPGGPSPSERDRQYCELCGKMENLLRCSRCRSSFYCCKEHQRQDWKKHKLVCQGSEGALGHGVGPHQHSGPAPPAAVPPPRAGA
REPRKAAARRDNASGDAAKGKVKAKPPADPAAAASPCRAAAGGQGSAVAAEAEPGKEEPPARSSLFQEKANLYPPSNTPGDALSPGGGLR
PNGQTKPLPALKLALEYIVPCMNKHGICVVDDFLGKETGQQIGDEVRALHDTGKFTDGQLVSQKSDSSKDIRGDKITWIEGKEPGCETIG
LLMSSMDDLIRHCNGKLGSYKINGRTKSIDPGQQFTWENSNLEVNKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAY
IATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPARGTETCGLIQVTLLDTVELATYTVRTFALHKSGSSEKRELRQFQ
FMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFI
HEALLEAATCGHTEVPARNLYAHIQKLGQVPPGESVTAMELEFKLLASSKAHTSRFISANLPCNKFKNRLVNIMPYELTRVCLQPIRGVE
GSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILR
EFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQT
VKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYAT

--------------------------------------------------------------
>25493_25493_2_EGLN1-PTPRF_EGLN1_chr1_231556744_ENST00000366641_PTPRF_chr1_44083116_ENST00000372413_length(transcript)=7369nt_BP=4047nt
TTAGGGGCAGAAAAACATTTGTAATAATTAATGGCTTTGAGAGACACAAGGCTTTGTTTGCCCCAGAGTATTAGTTAACCCACCTAGTGC
TCCTAATCATACAATATTAAGGATTGGGAGGGACATTCATTGCCTCACTCTCTATTTGTTTCACCTTCTGTAAAATTGGTAGAATAATAG
TACCCACTTCATAGCATTGTATGATGATTAAATTGGTTAATATTTTTAAAATGCTTAGAACACAGATTGGGCACATAACAGCAAGCACCA
CATGTGTTTATAAGATAAATTCCTTTGTGTTGCCTTCCGTTAAAGTTTAAATAAGTAAATAAATAAATAAATACTTGCATGACATTTTGA
AGTCTCTCTATAACATCTGAGTAAGTGGCGGCTGCGACAATGCTACTGGAGTTCCAGAATCGTGTTGGTGACAAGATTGTTCACCAGCAT
ATGGTGTGGTGAAAACTCACTAATTTGGAATTAGTTCAGATTATTAAGCCTGAATAGGTGAAAATCCTGAAATCAAGGATCTTTGGAACT
ATTTGAAATCAGTATTTTATATTTTCCTGTTGTATTCATTAAAGTGTTGCAAGTGTTCTATTTGATGGATTAAGTATATTTAGGATATAC
ATGTTCAATTTGTGATTTTGTATACTTAATTGGAACAAGAAAGCTAATAAAGGTTTTGATATGGACATCTATTCTTTTAAGTAAACTTCA
ATGAAAATATATGAGTAGAGCATATAGAGATGTAAATAATTTGTGGACACACCACAGACTGAAATAGCAAATTTAAAAGAAATTGTTGGA
AGAATCAAGTGTTTGTGGAATGAGTCCTCCTAGTAAAGTTCCTGCTCTTGTGAATAATTAAGCCTCATGTATAATTACTATAGCAAAAGG
AAGCCTAAGAAGTATTAGACTCTACTTGTATTTAAATTACATTTTACATAATTTATGTGTATGAAAAATGTTTTAAATGCTTATTTTCGT
AAGCCATGAGATAGCTCCTTTATATTTTAAGAATTTCTGAATTAATTTGCTTGGATTTTATTAGTGCAAATGGCAGAGCTAGCAATTCCT
TTTTCTGTGTTCCCATTCCATCCTATTCATCCCTCTTTTAGGAAACTCTGAACTCTGGATTGTCCTTGTTTACATACCTGCCTCCTGCAT
TGGACTATGTGTCTCTGAGTGTAGTATGACTAATTCATTTGTTTGTCAAGGACTCTCAATGCATTTGTTGAACAGCCTAATTAGTAATGT
CTGCAACAATGACATTTTACTGTATTTAATAAAGCTCTGGGAAAGTAGGATACACATAAGACAGGTCTAGGTCTAAATTCTTTACAGAAA
CTTGGATTTTTAGTTCGGTTTGAAATTTGAAGATGTGAGTATATTTATCTCAGTTTCCCAAAGGACAAGCTAATTGGAATTATCATCCTC
TTTCACTTGATTGGATCCCCAGAATGCCATTTACGCATGCAGCAGGATTTTATAACAGTTTTAAATTCTGTATATTTGATGAAGAGGTTT
TATATTTTTGGATTCAAGCCTCTTTTTAAACTTCTACAATATGGTTTACAATAATTCCTTATATCCTGCTTTTGAAATACATATTACAAC
TTTTTAAGTTTGGAAGGCTATATTTCAAGGACTGAAGTTACAGTATACTCAAGTGATACACAAGCCTAGCACCCCACTTTCCACATAGTG
TTCGATAAAGATTGATAAACTCGAAATCACAGACCTTTTAATTCTTAAGACAAATAGCAGCAGAAAGAAACATCTTTGGCTTATTTCTGG
TAAGGTTTTTATGCTCTGTAAAACAAAGAATTGTATTCATCCGCGCAGCACAGATTCTATTAAAAATAAATGTGAGAGTCGTTAATGTAG
TACTGCTCATTTACCATCAAAATTCACTTTTCAGGAATAATCCCATCAGTTTAAATTGGATATTGGAATGAGCATTGATTACATTTAACT
TGGTAGCCCAAAATTTCTTCATGGGGTTTTGAACTCGGCGGGATTTCAAAGGTTTTAAAAATGAGTTTTTGATTTTTTTTAAAACCCTCA
AATTTCATTACCTTTAAACTAGGTCGAAACGGGGCGCAAGAGATTGGATTAACACCATAGTAATACTTATTTTGTTCTTAACCATTTCAG
GGCTTCTTGAAATAGAGGCTGTATGGTGTAATGGAAAAAACAGCCTTGGAATCTGGGAGCCTGATTCCTGGATTCAGTCCCAGTTTTGCG
TGACCTTGGGCAAGTTACTTTACTTCTCTGAATTTCCGTTTCCTCCTCTGCAAAATGAGGATCGCAATAGCCACCTTGCAACCTTGACTG
GAGCGAGCCTCGCACACCCCGCGCCGGCCTGGAGGAAGAGCAGCCATGATTACGCCGCCTTCGCTCCGCTACCCGCTTGCGGCTGGCGCC
CTCCTCCAGCAGGTGTAGGCGCTGCCGCGCTGCCCCACGCCTTTCCGCCGCTCGCGGGCCTGCGCCTCGGCGTCCCCGAGGAGGCCGCTG
CGGGCTGAGGTAGCGCACCGGCCTCTCGGCGTCCCAGTCCGGTCCCGGGCGGAGGGAAAGCGGGCGACCCACCTCCGAGGCAGAAGCCGA
GGCCCGGCCCCGCCGAGTGCGGAGGAGCGCAGGCAGCCCCCGCCCCTCGGCCCTCCCCCCGGCCCTCCCGGCCCTCCCTCCGCCCCCTCC
GCCCTCGCGCGCCGCCCGCCCGGGTCGCCGCGGGGCCGTGGTGTACGTGCAGAGCGCGCAGAGCGAGTGGCGCCCGTATGCCCTGCGCTC
CTCCACAGCCTGGGCCGGGCCGCCCGGGACGCTGAGGCGGCGGCGGCGGCCGAGGGGGCCGGTCTTGCGCTCCCCAGGCCCGCGCGCCTG
AGCCCAGGTTGCCATTCGCCGCACAGGCCCTATTCTCTCAGCCCTCGGCGGCGATGAGGCGCTGAGGCGGCTGCCGGCGCTGCGCCGGAG
CTTAGGACTCGGAAGCGGCCGGGCCGAGGGCGTGGGGTGCCGGCCTCCCTGAGGCGAGGGTAGCGGGTGCATGGCGCAGTAACGGCCCCT
ATCTCTCTCCCCGCTCCCCAGCCTCGGGCGAGGCCGTCCGGCCGCTACCCCTCCTGCTCGGCCGCCGCAGTCGCCGTCGCCGCCGCCGCC
GCCGCCATGGCCAATGACAGCGGCGGGCCCGGCGGGCCGAGCCCGAGCGAGCGAGACCGGCAGTACTGCGAGCTGTGCGGGAAGATGGAG
AACCTGCTGCGCTGCAGCCGCTGCCGCAGCTCCTTCTACTGCTGCAAGGAGCACCAGCGTCAGGACTGGAAGAAGCACAAGCTCGTGTGC
CAGGGCAGCGAGGGCGCCCTCGGCCACGGAGTGGGCCCACACCAGCATTCCGGCCCCGCGCCGCCGGCTGCAGTGCCGCCGCCCAGGGCC
GGGGCCCGGGAGCCCAGGAAGGCAGCGGCGCGCCGGGACAACGCCTCCGGGGACGCGGCCAAGGGAAAAGTAAAGGCCAAGCCCCCGGCC
GACCCAGCGGCGGCCGCGTCGCCGTGTCGTGCGGCCGCCGGCGGCCAGGGCTCGGCGGTGGCTGCCGAAGCCGAGCCCGGCAAGGAGGAG
CCGCCGGCCCGCTCATCGCTGTTCCAGGAGAAGGCGAACCTGTACCCCCCAAGCAACACGCCCGGGGATGCGCTGAGCCCCGGCGGCGGC
CTGCGGCCCAACGGGCAGACGAAGCCCCTGCCGGCGCTGAAGCTGGCGCTCGAGTACATCGTGCCGTGCATGAACAAGCACGGCATCTGT
GTGGTGGACGACTTCCTCGGCAAGGAGACCGGACAGCAGATCGGCGACGAGGTGCGCGCCCTGCACGACACCGGGAAGTTCACGGACGGG
CAGCTGGTCAGCCAGAAGAGTGACTCGTCCAAGGACATCCGAGGCGATAAGATCACCTGGATCGAGGGCAAGGAGCCCGGCTGCGAAACC
ATTGGGCTGCTCATGAGCAGCATGGACGACCTGATACGCCACTGTAACGGGAAGCTGGGCAGCTACAAAATCAATGGCCGGACGAAATCC
ATCGACCCTGGACAGCAGTTCACGTGGGAGAATTCAAACCTGGAGGTGAACAAGCCCAAGAACCGCTATGCGAATGTCATCGCCTACGAC
CACTCTCGAGTCATCCTTACCTCTATCGATGGCGTCCCCGGGAGTGACTACATCAATGCCAACTACATCGATGGCTACCGCAAGCAGAAT
GCCTACATCGCCACGCAGGGCCCCCTGCCCGAGACCATGGGTGATTTCTGGAGGATGGTGTGGGAACAGCGCACGGCCACTGTGGTCATG
ATGACACGGCTGGAGGAGAAGTCCCGGGTAAAATGTGATCAGTACTGGCCAGCCCGTGGCACCGAGACCTGTGGCCTTATTCAGGTGACC
CTGTTGGACACAGTGGAGCTGGCCACATACACTGTGCGCACCTTCGCACTCCACAAGAGTGGCTCCAGTGAGAAGCGCGAGCTGCGTCAG
TTTCAGTTCATGGCCTGGCCAGACCATGGAGTTCCTGAGTACCCAACTCCCATCCTGGCCTTCCTACGACGGGTCAAGGCCTGCAACCCC
CTAGACGCAGGGCCCATGGTGGTGCACTGCAGCGCGGGCGTGGGCCGCACCGGCTGCTTCATCGTGATTGATGCCATGTTGGAGCGGATG
AAGCACGAGAAGACGGTGGACATCTATGGCCACGTGACCTGCATGCGATCACAGAGGAACTACATGGTGCAGACGGAGGACCAGTACGTG
TTCATCCATGAGGCGCTGCTGGAGGCTGCCACGTGCGGCCACACAGAGGTGCCTGCCCGCAACCTGTATGCCCACATCCAGAAGCTGGGC
CAAGTGCCTCCAGGGGAGAGTGTGACCGCCATGGAGCTCGAGTTCAAGTTGCTGGCCAGCTCCAAGGCCCACACGTCCCGCTTCATCAGC
GCCAACCTGCCCTGCAACAAGTTCAAGAACCGGCTGGTGAACATCATGCCCTACGAATTGACCCGTGTGTGTCTGCAGCCCATCCGTGGT
GTGGAGGGCTCTGACTACATCAATGCCAGCTTCCTGGATGGTTATAGACAGCAGAAGGCCTACATAGCTACACAGGGGCCTCTGGCAGAG
AGCACCGAGGACTTCTGGCGCATGCTATGGGAGCACAATTCCACCATCATCGTCATGCTGACCAAGCTTCGGGAGATGGGCAGGGAGAAA
TGCCACCAGTACTGGCCAGCAGAGCGCTCTGCTCGCTACCAGTACTTTGTTGTTGACCCGATGGCTGAGTACAACATGCCCCAGTATATC
CTGCGTGAGTTCAAGGTCACGGATGCCCGGGATGGGCAGTCAAGGACAATCCGGCAGTTCCAGTTCACAGACTGGCCAGAGCAGGGCGTG
CCCAAGACAGGCGAGGGATTCATTGACTTCATCGGGCAGGTGCATAAGACCAAGGAGCAGTTTGGACAGGATGGGCCTATCACGGTGCAC
TGCAGTGCTGGCGTGGGCCGCACCGGGGTGTTCATCACTCTGAGCATCGTCCTGGAGCGCATGCGCTACGAGGGCGTGGTCGACATGTTT
CAGACCGTGAAGACCCTGCGTACACAGCGTCCTGCCATGGTGCAGACAGAGGACCAGTATCAGCTGTGCTACCGTGCGGCCCTGGAGTAC
CTCGGCAGCTTTGACCACTATGCAACGTAACTACCGCTCCCCTCTCCTCCGCCACCCCCGCCGTGGGGCTCCGGAGGGGACCCAGCTCCT
CTGAGCCATACCGACCATCGTCCAGCCCTCCTACGCAGATGCTGTCACTGGCAGAGCACAGCCCACGGGGATCACAGCGTTTCAGGAACG
TTGCCACACCAATCAGAGAGCCTAGAACATCCCTGGGCAAGTGGATGGCCCAGCAGGCAGGCACTGTGGCCCTTCTGTCCACCAGACCCA
CCTGGAGCCCGCTTCAAGCTCTCTGTTGCGCTCCCGCATTTCTCATGCTTCTTCTCATGGGGTGGGGTTGGGGCAAAGCCTCCTTTTTAA
TACATTAAGTGGGGTAGACTGAGGGATTTTAGCCTCTTCCCTCTGATTTTTCCTTTCGCGAATCCGTATCTGCAGAATGGGCCACTGTAG
GGGTTGGGGTTTATTTTGTTTTGTTTTTTTTTTTCTTGAGTTCACTTTGGATCCTTATTTTGTATGACTTCTGCTGAAGGACAGAACATT
GCCTTCCTCGTGCAGAGCTGGGGCTGCCAGCCTGAGCGGAGGCTCGGCCGTGGGCCGGGAGGCAGTGCTGATCCGGCTGCTCCTCCAGCC
CTTCAGACGAGATCCTGTTTCAGCTAAATGCAGGGAAACTCAATGTTTTTTTAAGTTTTGTTTTCCCTTTAAAGCCTTTTTTTAGGCCAC
ATTGACAGTGGTGGGCGGGGAGAAGATAGGGAACACTCATCCCTGGTCGTCTATCCCAGTGTGTGTTTAACATTCACAGCCCAGAACCAC
AGATGTGTCTGGGAGAGCCTGGCAAGGCATTCCTCATCACCATCGTGTTTGCAAAGGTTAAAACAAAAACAAAAAACCACAAAAATAAAA
AACAAAAAAAACAAAAAACCCAAGAAAAAAAAAAAGAGTCAGCCCTTGGCTTCTGCTTCAAACCCTCAAGAGGGGAAGCAACTCCGTGTG
CCTGGGGTTCCCGAGGGAGCTGCTGGCTGACCTGGGCCCACAGAGCCTGGCTTTGGTCCCCAGCATTGCAGTATGGTGTGGTGTTTGTAG
GCTGTGGGGTCTGGCTGTGTGGCCAAGGTGAATAGCACAGGTTAGGGTGTGTGCCACACCCCATGCACCTCAGGGCCAAGCGGGGGCGTG
GCTGGCCTTTCAGGTCCAGGCCAGTGGGCCTGGTAGCACATGTCTGTCCTCAGAGCAGGGGCCAGATGATTTTCCTCCCTGGTTTGCAGC
TGTTTTCAAAGCCCCCGATAATCGCTCTTTTCCACTCCAAGATGCCCTCATAAACCAATGTGGCAAGACTACTGGACTTCTATCAATGGT
ACTCTAATCAGTCCTTATTATCCCAGCTTGCTGAGGGGCAGGGAGAGCGCCTCTTCCTCTGGGCAGCGCTATCTAGATAGGTAAGTGGGG
GCGGGGAAGGGTGCATAGCTGTTTTAGCTGAGGGACGTGGTGCCGACGTCCCCAAACCTAGCTAGGCTAAGTCAAGATCAACATTCCAGG
GTTGGTAATGTTGGATGATGAAACATTCATTTTTACCTTGTGGATGCTAGTGCTGTAGAGTTCACTGTTGTACACAGTCTGTTTTCTATT
TGTTAAGAAAAACTACAGCATCATTGCATAATTCTTGATGGTAATAAATTTGAATAATCAGATTTCTTACAAACCAGGA

>25493_25493_2_EGLN1-PTPRF_EGLN1_chr1_231556744_ENST00000366641_PTPRF_chr1_44083116_ENST00000372413_length(amino acids)=847AA_BP=297
MANDSGGPGGPSPSERDRQYCELCGKMENLLRCSRCRSSFYCCKEHQRQDWKKHKLVCQGSEGALGHGVGPHQHSGPAPPAAVPPPRAGA
REPRKAAARRDNASGDAAKGKVKAKPPADPAAAASPCRAAAGGQGSAVAAEAEPGKEEPPARSSLFQEKANLYPPSNTPGDALSPGGGLR
PNGQTKPLPALKLALEYIVPCMNKHGICVVDDFLGKETGQQIGDEVRALHDTGKFTDGQLVSQKSDSSKDIRGDKITWIEGKEPGCETIG
LLMSSMDDLIRHCNGKLGSYKINGRTKSIDPGQQFTWENSNLEVNKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAY
IATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPARGTETCGLIQVTLLDTVELATYTVRTFALHKSGSSEKRELRQFQ
FMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFI
HEALLEAATCGHTEVPARNLYAHIQKLGQVPPGESVTAMELEFKLLASSKAHTSRFISANLPCNKFKNRLVNIMPYELTRVCLQPIRGVE
GSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILR
EFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQT
VKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYAT

--------------------------------------------------------------
>25493_25493_3_EGLN1-PTPRF_EGLN1_chr1_231556744_ENST00000366641_PTPRF_chr1_44083116_ENST00000372414_length(transcript)=7369nt_BP=4047nt
TTAGGGGCAGAAAAACATTTGTAATAATTAATGGCTTTGAGAGACACAAGGCTTTGTTTGCCCCAGAGTATTAGTTAACCCACCTAGTGC
TCCTAATCATACAATATTAAGGATTGGGAGGGACATTCATTGCCTCACTCTCTATTTGTTTCACCTTCTGTAAAATTGGTAGAATAATAG
TACCCACTTCATAGCATTGTATGATGATTAAATTGGTTAATATTTTTAAAATGCTTAGAACACAGATTGGGCACATAACAGCAAGCACCA
CATGTGTTTATAAGATAAATTCCTTTGTGTTGCCTTCCGTTAAAGTTTAAATAAGTAAATAAATAAATAAATACTTGCATGACATTTTGA
AGTCTCTCTATAACATCTGAGTAAGTGGCGGCTGCGACAATGCTACTGGAGTTCCAGAATCGTGTTGGTGACAAGATTGTTCACCAGCAT
ATGGTGTGGTGAAAACTCACTAATTTGGAATTAGTTCAGATTATTAAGCCTGAATAGGTGAAAATCCTGAAATCAAGGATCTTTGGAACT
ATTTGAAATCAGTATTTTATATTTTCCTGTTGTATTCATTAAAGTGTTGCAAGTGTTCTATTTGATGGATTAAGTATATTTAGGATATAC
ATGTTCAATTTGTGATTTTGTATACTTAATTGGAACAAGAAAGCTAATAAAGGTTTTGATATGGACATCTATTCTTTTAAGTAAACTTCA
ATGAAAATATATGAGTAGAGCATATAGAGATGTAAATAATTTGTGGACACACCACAGACTGAAATAGCAAATTTAAAAGAAATTGTTGGA
AGAATCAAGTGTTTGTGGAATGAGTCCTCCTAGTAAAGTTCCTGCTCTTGTGAATAATTAAGCCTCATGTATAATTACTATAGCAAAAGG
AAGCCTAAGAAGTATTAGACTCTACTTGTATTTAAATTACATTTTACATAATTTATGTGTATGAAAAATGTTTTAAATGCTTATTTTCGT
AAGCCATGAGATAGCTCCTTTATATTTTAAGAATTTCTGAATTAATTTGCTTGGATTTTATTAGTGCAAATGGCAGAGCTAGCAATTCCT
TTTTCTGTGTTCCCATTCCATCCTATTCATCCCTCTTTTAGGAAACTCTGAACTCTGGATTGTCCTTGTTTACATACCTGCCTCCTGCAT
TGGACTATGTGTCTCTGAGTGTAGTATGACTAATTCATTTGTTTGTCAAGGACTCTCAATGCATTTGTTGAACAGCCTAATTAGTAATGT
CTGCAACAATGACATTTTACTGTATTTAATAAAGCTCTGGGAAAGTAGGATACACATAAGACAGGTCTAGGTCTAAATTCTTTACAGAAA
CTTGGATTTTTAGTTCGGTTTGAAATTTGAAGATGTGAGTATATTTATCTCAGTTTCCCAAAGGACAAGCTAATTGGAATTATCATCCTC
TTTCACTTGATTGGATCCCCAGAATGCCATTTACGCATGCAGCAGGATTTTATAACAGTTTTAAATTCTGTATATTTGATGAAGAGGTTT
TATATTTTTGGATTCAAGCCTCTTTTTAAACTTCTACAATATGGTTTACAATAATTCCTTATATCCTGCTTTTGAAATACATATTACAAC
TTTTTAAGTTTGGAAGGCTATATTTCAAGGACTGAAGTTACAGTATACTCAAGTGATACACAAGCCTAGCACCCCACTTTCCACATAGTG
TTCGATAAAGATTGATAAACTCGAAATCACAGACCTTTTAATTCTTAAGACAAATAGCAGCAGAAAGAAACATCTTTGGCTTATTTCTGG
TAAGGTTTTTATGCTCTGTAAAACAAAGAATTGTATTCATCCGCGCAGCACAGATTCTATTAAAAATAAATGTGAGAGTCGTTAATGTAG
TACTGCTCATTTACCATCAAAATTCACTTTTCAGGAATAATCCCATCAGTTTAAATTGGATATTGGAATGAGCATTGATTACATTTAACT
TGGTAGCCCAAAATTTCTTCATGGGGTTTTGAACTCGGCGGGATTTCAAAGGTTTTAAAAATGAGTTTTTGATTTTTTTTAAAACCCTCA
AATTTCATTACCTTTAAACTAGGTCGAAACGGGGCGCAAGAGATTGGATTAACACCATAGTAATACTTATTTTGTTCTTAACCATTTCAG
GGCTTCTTGAAATAGAGGCTGTATGGTGTAATGGAAAAAACAGCCTTGGAATCTGGGAGCCTGATTCCTGGATTCAGTCCCAGTTTTGCG
TGACCTTGGGCAAGTTACTTTACTTCTCTGAATTTCCGTTTCCTCCTCTGCAAAATGAGGATCGCAATAGCCACCTTGCAACCTTGACTG
GAGCGAGCCTCGCACACCCCGCGCCGGCCTGGAGGAAGAGCAGCCATGATTACGCCGCCTTCGCTCCGCTACCCGCTTGCGGCTGGCGCC
CTCCTCCAGCAGGTGTAGGCGCTGCCGCGCTGCCCCACGCCTTTCCGCCGCTCGCGGGCCTGCGCCTCGGCGTCCCCGAGGAGGCCGCTG
CGGGCTGAGGTAGCGCACCGGCCTCTCGGCGTCCCAGTCCGGTCCCGGGCGGAGGGAAAGCGGGCGACCCACCTCCGAGGCAGAAGCCGA
GGCCCGGCCCCGCCGAGTGCGGAGGAGCGCAGGCAGCCCCCGCCCCTCGGCCCTCCCCCCGGCCCTCCCGGCCCTCCCTCCGCCCCCTCC
GCCCTCGCGCGCCGCCCGCCCGGGTCGCCGCGGGGCCGTGGTGTACGTGCAGAGCGCGCAGAGCGAGTGGCGCCCGTATGCCCTGCGCTC
CTCCACAGCCTGGGCCGGGCCGCCCGGGACGCTGAGGCGGCGGCGGCGGCCGAGGGGGCCGGTCTTGCGCTCCCCAGGCCCGCGCGCCTG
AGCCCAGGTTGCCATTCGCCGCACAGGCCCTATTCTCTCAGCCCTCGGCGGCGATGAGGCGCTGAGGCGGCTGCCGGCGCTGCGCCGGAG
CTTAGGACTCGGAAGCGGCCGGGCCGAGGGCGTGGGGTGCCGGCCTCCCTGAGGCGAGGGTAGCGGGTGCATGGCGCAGTAACGGCCCCT
ATCTCTCTCCCCGCTCCCCAGCCTCGGGCGAGGCCGTCCGGCCGCTACCCCTCCTGCTCGGCCGCCGCAGTCGCCGTCGCCGCCGCCGCC
GCCGCCATGGCCAATGACAGCGGCGGGCCCGGCGGGCCGAGCCCGAGCGAGCGAGACCGGCAGTACTGCGAGCTGTGCGGGAAGATGGAG
AACCTGCTGCGCTGCAGCCGCTGCCGCAGCTCCTTCTACTGCTGCAAGGAGCACCAGCGTCAGGACTGGAAGAAGCACAAGCTCGTGTGC
CAGGGCAGCGAGGGCGCCCTCGGCCACGGAGTGGGCCCACACCAGCATTCCGGCCCCGCGCCGCCGGCTGCAGTGCCGCCGCCCAGGGCC
GGGGCCCGGGAGCCCAGGAAGGCAGCGGCGCGCCGGGACAACGCCTCCGGGGACGCGGCCAAGGGAAAAGTAAAGGCCAAGCCCCCGGCC
GACCCAGCGGCGGCCGCGTCGCCGTGTCGTGCGGCCGCCGGCGGCCAGGGCTCGGCGGTGGCTGCCGAAGCCGAGCCCGGCAAGGAGGAG
CCGCCGGCCCGCTCATCGCTGTTCCAGGAGAAGGCGAACCTGTACCCCCCAAGCAACACGCCCGGGGATGCGCTGAGCCCCGGCGGCGGC
CTGCGGCCCAACGGGCAGACGAAGCCCCTGCCGGCGCTGAAGCTGGCGCTCGAGTACATCGTGCCGTGCATGAACAAGCACGGCATCTGT
GTGGTGGACGACTTCCTCGGCAAGGAGACCGGACAGCAGATCGGCGACGAGGTGCGCGCCCTGCACGACACCGGGAAGTTCACGGACGGG
CAGCTGGTCAGCCAGAAGAGTGACTCGTCCAAGGACATCCGAGGCGATAAGATCACCTGGATCGAGGGCAAGGAGCCCGGCTGCGAAACC
ATTGGGCTGCTCATGAGCAGCATGGACGACCTGATACGCCACTGTAACGGGAAGCTGGGCAGCTACAAAATCAATGGCCGGACGAAATCC
ATCGACCCTGGACAGCAGTTCACGTGGGAGAATTCAAACCTGGAGGTGAACAAGCCCAAGAACCGCTATGCGAATGTCATCGCCTACGAC
CACTCTCGAGTCATCCTTACCTCTATCGATGGCGTCCCCGGGAGTGACTACATCAATGCCAACTACATCGATGGCTACCGCAAGCAGAAT
GCCTACATCGCCACGCAGGGCCCCCTGCCCGAGACCATGGGTGATTTCTGGAGGATGGTGTGGGAACAGCGCACGGCCACTGTGGTCATG
ATGACACGGCTGGAGGAGAAGTCCCGGGTAAAATGTGATCAGTACTGGCCAGCCCGTGGCACCGAGACCTGTGGCCTTATTCAGGTGACC
CTGTTGGACACAGTGGAGCTGGCCACATACACTGTGCGCACCTTCGCACTCCACAAGAGTGGCTCCAGTGAGAAGCGCGAGCTGCGTCAG
TTTCAGTTCATGGCCTGGCCAGACCATGGAGTTCCTGAGTACCCAACTCCCATCCTGGCCTTCCTACGACGGGTCAAGGCCTGCAACCCC
CTAGACGCAGGGCCCATGGTGGTGCACTGCAGCGCGGGCGTGGGCCGCACCGGCTGCTTCATCGTGATTGATGCCATGTTGGAGCGGATG
AAGCACGAGAAGACGGTGGACATCTATGGCCACGTGACCTGCATGCGATCACAGAGGAACTACATGGTGCAGACGGAGGACCAGTACGTG
TTCATCCATGAGGCGCTGCTGGAGGCTGCCACGTGCGGCCACACAGAGGTGCCTGCCCGCAACCTGTATGCCCACATCCAGAAGCTGGGC
CAAGTGCCTCCAGGGGAGAGTGTGACCGCCATGGAGCTCGAGTTCAAGTTGCTGGCCAGCTCCAAGGCCCACACGTCCCGCTTCATCAGC
GCCAACCTGCCCTGCAACAAGTTCAAGAACCGGCTGGTGAACATCATGCCCTACGAATTGACCCGTGTGTGTCTGCAGCCCATCCGTGGT
GTGGAGGGCTCTGACTACATCAATGCCAGCTTCCTGGATGGTTATAGACAGCAGAAGGCCTACATAGCTACACAGGGGCCTCTGGCAGAG
AGCACCGAGGACTTCTGGCGCATGCTATGGGAGCACAATTCCACCATCATCGTCATGCTGACCAAGCTTCGGGAGATGGGCAGGGAGAAA
TGCCACCAGTACTGGCCAGCAGAGCGCTCTGCTCGCTACCAGTACTTTGTTGTTGACCCGATGGCTGAGTACAACATGCCCCAGTATATC
CTGCGTGAGTTCAAGGTCACGGATGCCCGGGATGGGCAGTCAAGGACAATCCGGCAGTTCCAGTTCACAGACTGGCCAGAGCAGGGCGTG
CCCAAGACAGGCGAGGGATTCATTGACTTCATCGGGCAGGTGCATAAGACCAAGGAGCAGTTTGGACAGGATGGGCCTATCACGGTGCAC
TGCAGTGCTGGCGTGGGCCGCACCGGGGTGTTCATCACTCTGAGCATCGTCCTGGAGCGCATGCGCTACGAGGGCGTGGTCGACATGTTT
CAGACCGTGAAGACCCTGCGTACACAGCGTCCTGCCATGGTGCAGACAGAGGACCAGTATCAGCTGTGCTACCGTGCGGCCCTGGAGTAC
CTCGGCAGCTTTGACCACTATGCAACGTAACTACCGCTCCCCTCTCCTCCGCCACCCCCGCCGTGGGGCTCCGGAGGGGACCCAGCTCCT
CTGAGCCATACCGACCATCGTCCAGCCCTCCTACGCAGATGCTGTCACTGGCAGAGCACAGCCCACGGGGATCACAGCGTTTCAGGAACG
TTGCCACACCAATCAGAGAGCCTAGAACATCCCTGGGCAAGTGGATGGCCCAGCAGGCAGGCACTGTGGCCCTTCTGTCCACCAGACCCA
CCTGGAGCCCGCTTCAAGCTCTCTGTTGCGCTCCCGCATTTCTCATGCTTCTTCTCATGGGGTGGGGTTGGGGCAAAGCCTCCTTTTTAA
TACATTAAGTGGGGTAGACTGAGGGATTTTAGCCTCTTCCCTCTGATTTTTCCTTTCGCGAATCCGTATCTGCAGAATGGGCCACTGTAG
GGGTTGGGGTTTATTTTGTTTTGTTTTTTTTTTTCTTGAGTTCACTTTGGATCCTTATTTTGTATGACTTCTGCTGAAGGACAGAACATT
GCCTTCCTCGTGCAGAGCTGGGGCTGCCAGCCTGAGCGGAGGCTCGGCCGTGGGCCGGGAGGCAGTGCTGATCCGGCTGCTCCTCCAGCC
CTTCAGACGAGATCCTGTTTCAGCTAAATGCAGGGAAACTCAATGTTTTTTTAAGTTTTGTTTTCCCTTTAAAGCCTTTTTTTAGGCCAC
ATTGACAGTGGTGGGCGGGGAGAAGATAGGGAACACTCATCCCTGGTCGTCTATCCCAGTGTGTGTTTAACATTCACAGCCCAGAACCAC
AGATGTGTCTGGGAGAGCCTGGCAAGGCATTCCTCATCACCATCGTGTTTGCAAAGGTTAAAACAAAAACAAAAAACCACAAAAATAAAA
AACAAAAAAAACAAAAAACCCAAGAAAAAAAAAAAGAGTCAGCCCTTGGCTTCTGCTTCAAACCCTCAAGAGGGGAAGCAACTCCGTGTG
CCTGGGGTTCCCGAGGGAGCTGCTGGCTGACCTGGGCCCACAGAGCCTGGCTTTGGTCCCCAGCATTGCAGTATGGTGTGGTGTTTGTAG
GCTGTGGGGTCTGGCTGTGTGGCCAAGGTGAATAGCACAGGTTAGGGTGTGTGCCACACCCCATGCACCTCAGGGCCAAGCGGGGGCGTG
GCTGGCCTTTCAGGTCCAGGCCAGTGGGCCTGGTAGCACATGTCTGTCCTCAGAGCAGGGGCCAGATGATTTTCCTCCCTGGTTTGCAGC
TGTTTTCAAAGCCCCCGATAATCGCTCTTTTCCACTCCAAGATGCCCTCATAAACCAATGTGGCAAGACTACTGGACTTCTATCAATGGT
ACTCTAATCAGTCCTTATTATCCCAGCTTGCTGAGGGGCAGGGAGAGCGCCTCTTCCTCTGGGCAGCGCTATCTAGATAGGTAAGTGGGG
GCGGGGAAGGGTGCATAGCTGTTTTAGCTGAGGGACGTGGTGCCGACGTCCCCAAACCTAGCTAGGCTAAGTCAAGATCAACATTCCAGG
GTTGGTAATGTTGGATGATGAAACATTCATTTTTACCTTGTGGATGCTAGTGCTGTAGAGTTCACTGTTGTACACAGTCTGTTTTCTATT
TGTTAAGAAAAACTACAGCATCATTGCATAATTCTTGATGGTAATAAATTTGAATAATCAGATTTCTTACAAACCAGGA

>25493_25493_3_EGLN1-PTPRF_EGLN1_chr1_231556744_ENST00000366641_PTPRF_chr1_44083116_ENST00000372414_length(amino acids)=847AA_BP=297
MANDSGGPGGPSPSERDRQYCELCGKMENLLRCSRCRSSFYCCKEHQRQDWKKHKLVCQGSEGALGHGVGPHQHSGPAPPAAVPPPRAGA
REPRKAAARRDNASGDAAKGKVKAKPPADPAAAASPCRAAAGGQGSAVAAEAEPGKEEPPARSSLFQEKANLYPPSNTPGDALSPGGGLR
PNGQTKPLPALKLALEYIVPCMNKHGICVVDDFLGKETGQQIGDEVRALHDTGKFTDGQLVSQKSDSSKDIRGDKITWIEGKEPGCETIG
LLMSSMDDLIRHCNGKLGSYKINGRTKSIDPGQQFTWENSNLEVNKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAY
IATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPARGTETCGLIQVTLLDTVELATYTVRTFALHKSGSSEKRELRQFQ
FMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFI
HEALLEAATCGHTEVPARNLYAHIQKLGQVPPGESVTAMELEFKLLASSKAHTSRFISANLPCNKFKNRLVNIMPYELTRVCLQPIRGVE
GSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILR
EFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQT
VKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYAT

--------------------------------------------------------------
>25493_25493_4_EGLN1-PTPRF_EGLN1_chr1_231556744_ENST00000366641_PTPRF_chr1_44083116_ENST00000422171_length(transcript)=6539nt_BP=4047nt
TTAGGGGCAGAAAAACATTTGTAATAATTAATGGCTTTGAGAGACACAAGGCTTTGTTTGCCCCAGAGTATTAGTTAACCCACCTAGTGC
TCCTAATCATACAATATTAAGGATTGGGAGGGACATTCATTGCCTCACTCTCTATTTGTTTCACCTTCTGTAAAATTGGTAGAATAATAG
TACCCACTTCATAGCATTGTATGATGATTAAATTGGTTAATATTTTTAAAATGCTTAGAACACAGATTGGGCACATAACAGCAAGCACCA
CATGTGTTTATAAGATAAATTCCTTTGTGTTGCCTTCCGTTAAAGTTTAAATAAGTAAATAAATAAATAAATACTTGCATGACATTTTGA
AGTCTCTCTATAACATCTGAGTAAGTGGCGGCTGCGACAATGCTACTGGAGTTCCAGAATCGTGTTGGTGACAAGATTGTTCACCAGCAT
ATGGTGTGGTGAAAACTCACTAATTTGGAATTAGTTCAGATTATTAAGCCTGAATAGGTGAAAATCCTGAAATCAAGGATCTTTGGAACT
ATTTGAAATCAGTATTTTATATTTTCCTGTTGTATTCATTAAAGTGTTGCAAGTGTTCTATTTGATGGATTAAGTATATTTAGGATATAC
ATGTTCAATTTGTGATTTTGTATACTTAATTGGAACAAGAAAGCTAATAAAGGTTTTGATATGGACATCTATTCTTTTAAGTAAACTTCA
ATGAAAATATATGAGTAGAGCATATAGAGATGTAAATAATTTGTGGACACACCACAGACTGAAATAGCAAATTTAAAAGAAATTGTTGGA
AGAATCAAGTGTTTGTGGAATGAGTCCTCCTAGTAAAGTTCCTGCTCTTGTGAATAATTAAGCCTCATGTATAATTACTATAGCAAAAGG
AAGCCTAAGAAGTATTAGACTCTACTTGTATTTAAATTACATTTTACATAATTTATGTGTATGAAAAATGTTTTAAATGCTTATTTTCGT
AAGCCATGAGATAGCTCCTTTATATTTTAAGAATTTCTGAATTAATTTGCTTGGATTTTATTAGTGCAAATGGCAGAGCTAGCAATTCCT
TTTTCTGTGTTCCCATTCCATCCTATTCATCCCTCTTTTAGGAAACTCTGAACTCTGGATTGTCCTTGTTTACATACCTGCCTCCTGCAT
TGGACTATGTGTCTCTGAGTGTAGTATGACTAATTCATTTGTTTGTCAAGGACTCTCAATGCATTTGTTGAACAGCCTAATTAGTAATGT
CTGCAACAATGACATTTTACTGTATTTAATAAAGCTCTGGGAAAGTAGGATACACATAAGACAGGTCTAGGTCTAAATTCTTTACAGAAA
CTTGGATTTTTAGTTCGGTTTGAAATTTGAAGATGTGAGTATATTTATCTCAGTTTCCCAAAGGACAAGCTAATTGGAATTATCATCCTC
TTTCACTTGATTGGATCCCCAGAATGCCATTTACGCATGCAGCAGGATTTTATAACAGTTTTAAATTCTGTATATTTGATGAAGAGGTTT
TATATTTTTGGATTCAAGCCTCTTTTTAAACTTCTACAATATGGTTTACAATAATTCCTTATATCCTGCTTTTGAAATACATATTACAAC
TTTTTAAGTTTGGAAGGCTATATTTCAAGGACTGAAGTTACAGTATACTCAAGTGATACACAAGCCTAGCACCCCACTTTCCACATAGTG
TTCGATAAAGATTGATAAACTCGAAATCACAGACCTTTTAATTCTTAAGACAAATAGCAGCAGAAAGAAACATCTTTGGCTTATTTCTGG
TAAGGTTTTTATGCTCTGTAAAACAAAGAATTGTATTCATCCGCGCAGCACAGATTCTATTAAAAATAAATGTGAGAGTCGTTAATGTAG
TACTGCTCATTTACCATCAAAATTCACTTTTCAGGAATAATCCCATCAGTTTAAATTGGATATTGGAATGAGCATTGATTACATTTAACT
TGGTAGCCCAAAATTTCTTCATGGGGTTTTGAACTCGGCGGGATTTCAAAGGTTTTAAAAATGAGTTTTTGATTTTTTTTAAAACCCTCA
AATTTCATTACCTTTAAACTAGGTCGAAACGGGGCGCAAGAGATTGGATTAACACCATAGTAATACTTATTTTGTTCTTAACCATTTCAG
GGCTTCTTGAAATAGAGGCTGTATGGTGTAATGGAAAAAACAGCCTTGGAATCTGGGAGCCTGATTCCTGGATTCAGTCCCAGTTTTGCG
TGACCTTGGGCAAGTTACTTTACTTCTCTGAATTTCCGTTTCCTCCTCTGCAAAATGAGGATCGCAATAGCCACCTTGCAACCTTGACTG
GAGCGAGCCTCGCACACCCCGCGCCGGCCTGGAGGAAGAGCAGCCATGATTACGCCGCCTTCGCTCCGCTACCCGCTTGCGGCTGGCGCC
CTCCTCCAGCAGGTGTAGGCGCTGCCGCGCTGCCCCACGCCTTTCCGCCGCTCGCGGGCCTGCGCCTCGGCGTCCCCGAGGAGGCCGCTG
CGGGCTGAGGTAGCGCACCGGCCTCTCGGCGTCCCAGTCCGGTCCCGGGCGGAGGGAAAGCGGGCGACCCACCTCCGAGGCAGAAGCCGA
GGCCCGGCCCCGCCGAGTGCGGAGGAGCGCAGGCAGCCCCCGCCCCTCGGCCCTCCCCCCGGCCCTCCCGGCCCTCCCTCCGCCCCCTCC
GCCCTCGCGCGCCGCCCGCCCGGGTCGCCGCGGGGCCGTGGTGTACGTGCAGAGCGCGCAGAGCGAGTGGCGCCCGTATGCCCTGCGCTC
CTCCACAGCCTGGGCCGGGCCGCCCGGGACGCTGAGGCGGCGGCGGCGGCCGAGGGGGCCGGTCTTGCGCTCCCCAGGCCCGCGCGCCTG
AGCCCAGGTTGCCATTCGCCGCACAGGCCCTATTCTCTCAGCCCTCGGCGGCGATGAGGCGCTGAGGCGGCTGCCGGCGCTGCGCCGGAG
CTTAGGACTCGGAAGCGGCCGGGCCGAGGGCGTGGGGTGCCGGCCTCCCTGAGGCGAGGGTAGCGGGTGCATGGCGCAGTAACGGCCCCT
ATCTCTCTCCCCGCTCCCCAGCCTCGGGCGAGGCCGTCCGGCCGCTACCCCTCCTGCTCGGCCGCCGCAGTCGCCGTCGCCGCCGCCGCC
GCCGCCATGGCCAATGACAGCGGCGGGCCCGGCGGGCCGAGCCCGAGCGAGCGAGACCGGCAGTACTGCGAGCTGTGCGGGAAGATGGAG
AACCTGCTGCGCTGCAGCCGCTGCCGCAGCTCCTTCTACTGCTGCAAGGAGCACCAGCGTCAGGACTGGAAGAAGCACAAGCTCGTGTGC
CAGGGCAGCGAGGGCGCCCTCGGCCACGGAGTGGGCCCACACCAGCATTCCGGCCCCGCGCCGCCGGCTGCAGTGCCGCCGCCCAGGGCC
GGGGCCCGGGAGCCCAGGAAGGCAGCGGCGCGCCGGGACAACGCCTCCGGGGACGCGGCCAAGGGAAAAGTAAAGGCCAAGCCCCCGGCC
GACCCAGCGGCGGCCGCGTCGCCGTGTCGTGCGGCCGCCGGCGGCCAGGGCTCGGCGGTGGCTGCCGAAGCCGAGCCCGGCAAGGAGGAG
CCGCCGGCCCGCTCATCGCTGTTCCAGGAGAAGGCGAACCTGTACCCCCCAAGCAACACGCCCGGGGATGCGCTGAGCCCCGGCGGCGGC
CTGCGGCCCAACGGGCAGACGAAGCCCCTGCCGGCGCTGAAGCTGGCGCTCGAGTACATCGTGCCGTGCATGAACAAGCACGGCATCTGT
GTGGTGGACGACTTCCTCGGCAAGGAGACCGGACAGCAGATCGGCGACGAGGTGCGCGCCCTGCACGACACCGGGAAGTTCACGGACGGG
CAGCTGGTCAGCCAGAAGAGTGACTCGTCCAAGGACATCCGAGGCGATAAGATCACCTGGATCGAGGGCAAGGAGCCCGGCTGCGAAACC
ATTGGGCTGCTCATGAGCAGCATGGACGACCTGATACGCCACTGTAACGGGAAGCTGGGCAGCTACAAAATCAATGGCCGGACGAAATCC
ATCGACCCTGGACAGCAGTTCACGTGGGAGAATTCAAACCTGGAGGTGAACAAGCCCAAGAACCGCTATGCGAATGTCATCGCCTACGAC
CACTCTCGAGTCATCCTTACCTCTATCGATGGCGTCCCCGGGAGTGACTACATCAATGCCAACTACATCGATGGCTACCGCAAGCAGAAT
GCCTACATCGCCACGCAGGGCCCCCTGCCCGAGACCATGGGTGATTTCTGGAGGATGGTGTGGGAACAGCGCACGGCCACTGTGGTCATG
ATGACACGGCTGGAGGAGAAGTCCCGGGTAAAATGTGATCAGTACTGGCCAGCCCGTGGCACCGAGACCTGTGGCCTTATTCAGGTGACC
CTGTTGGACACAGTGGAGCTGGCCACATACACTGTGCGCACCTTCGCACTCCACAAGAGTGGCTCCAGTGAGAAGCGCGAGCTGCGTCAG
TTTCAGTTCATGGCCTGGCCAGACCATGGAGTTCCTGAGTACCCAACTCCCATCCTGGCCTTCCTACGACGGGTCAAGGCCTGCAACCCC
CTAGACGCAGGGCCCATGGTGGTGCACTGCAGCGCGGGCGTGGGCCGCACCGGCTGCTTCATCGTGATTGATGCCATGTTGGAGCGGATG
AAGCACGAGAAGACGGTGGACATCTATGGCCACGTGACCTGCATGCGATCACAGAGGAACTACATGGTGCAGACGGAGGACCAGTACGTG
TTCATCCATGAGGCGCTGCTGGAGGCTGCCACGTGCGGCCACACAGAGGTGCCTGCCCGCAACCTGTATGCCCACATCCAGAAGCTGGGC
CAAGTGCCTCCAGGGGAGAGTGTGACCGCCATGGAGCTCGAGTTCAAGTTGCTGGCCAGCTCCAAGGCCCACACGTCCCGCTTCATCAGC
GCCAACCTGCCCTGCAACAAGTTCAAGAACCGGCTGGTGAACATCATGCCCTACGAATTGACCCGTGTGTGTCTGCAGCCCATCCGTGGT
GTGGAGGGCTCTGACTACATCAATGCCAGCTTCCTGGATGGTTATAGACAGCAGAAGGCCTACATAGCTACACAGGGGCCTCTGGCAGAG
AGCACCGAGGACTTCTGGCGCATGCTATGGGAGCACAATTCCACCATCATCGTCATGCTGACCAAGCTTCGGGAGATGGGCAGGGAGAAA
TGCCACCAGTACTGGCCAGCAGAGCGCTCTGCTCGCTACCAGTACTTTGTTGTTGACCCGATGGCTGAGTACAACATGCCCCAGTATATC
CTGCGTGAGTTCAAGGTCACGGATGCCCGGGATGGGCAGTCAAGGACAATCCGGCAGTTCCAGTTCACAGACTGGCCAGAGCAGGGCGTG
CCCAAGACAGGCGAGGGATTCATTGACTTCATCGGGCAGGTGCATAAGACCAAGGAGCAGTTTGGACAGGATGGGCCTATCACGGTGCAC
TGCAGTGCTGGCGTGGGCCGCACCGGGGTGTTCATCACTCTGAGCATCGTCCTGGAGCGCATGCGCTACGAGGGCGTGGTCGACATGTTT
CAGACCGTGAAGACCCTGCGTACACAGCGTCCTGCCATGGTGCAGACAGAGGACCAGTATCAGCTGTGCTACCGTGCGGCCCTGGAGTAC
CTCGGCAGCTTTGACCACTATGCAACGTAACTACCGCTCCCCTCTCCTCCGCCACCCCCGCCGTGGGGCTCCGGAGGGGACCCAGCTCCT
CTGAGCCATACCGACCATCGTCCAGCCCTCCTACGCAGATGCTGTCACTGGCAGAGCACAGCCCACGGGGATCACAGCGTTTCAGGAACG
TTGCCACACCAATCAGAGAGCCTAGAACATCCCTGGGCAAGTGGATGGCCCAGCAGGCAGGCACTGTGGCCCTTCTGTCCACCAGACCCA
CCTGGAGCCCGCTTCAAGCTCTCTGTTGCGCTCCCGCATTTCTCATGCTTCTTCTCATGGGGTGGGGTTGGGGCAAAGCCTCCTTTTTAA
TACATTAAGTGGGGTAGACTGAGGGATTTTAGCCTCTTCCCTCTGATTTTTCCTTTCGCGAATCCGTATCTGCAGAATGGGCCACTGTAG
GGGTTGGGGTTTATTTTGTTTTGTTTTTTTTTTTCTTGAGTTCACTTTGGATCCTTATTTTGTATGACTTCTGCTGAAGGACAGAACATT
GCCTTCCTCGTGCAGAGCTGGGGCTGCCAGCCTGAGCGGAGGCTCGGCCGTGGGCCGGGAGGCAGTGCTGATCCGGCTGCTCCTCCAGCC
CTTCAGACGAGATCCTGTTTCAGCTAAATGCAGGGAAACTCAATGTTTTTTTAAGTTTTGTTTTCCCTTTAAAGCCTTTTTTTAGGCCAC
ATTGACAGTGGTGGGCGGGGAGAAGATAGGGAACACTCATCCCTGGTCGTCTATCCCAGTGTGTGTTTAACATTCACAGCCCAGAACCAC
AGATGTGTCTGGGAGAGCCTGGCAAGGCATTCCTCATCACCATCGTGTTTGCAAAGGTT

>25493_25493_4_EGLN1-PTPRF_EGLN1_chr1_231556744_ENST00000366641_PTPRF_chr1_44083116_ENST00000422171_length(amino acids)=847AA_BP=297
MANDSGGPGGPSPSERDRQYCELCGKMENLLRCSRCRSSFYCCKEHQRQDWKKHKLVCQGSEGALGHGVGPHQHSGPAPPAAVPPPRAGA
REPRKAAARRDNASGDAAKGKVKAKPPADPAAAASPCRAAAGGQGSAVAAEAEPGKEEPPARSSLFQEKANLYPPSNTPGDALSPGGGLR
PNGQTKPLPALKLALEYIVPCMNKHGICVVDDFLGKETGQQIGDEVRALHDTGKFTDGQLVSQKSDSSKDIRGDKITWIEGKEPGCETIG
LLMSSMDDLIRHCNGKLGSYKINGRTKSIDPGQQFTWENSNLEVNKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAY
IATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPARGTETCGLIQVTLLDTVELATYTVRTFALHKSGSSEKRELRQFQ
FMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFI
HEALLEAATCGHTEVPARNLYAHIQKLGQVPPGESVTAMELEFKLLASSKAHTSRFISANLPCNKFKNRLVNIMPYELTRVCLQPIRGVE
GSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILR
EFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQT
VKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYAT

--------------------------------------------------------------
>25493_25493_5_EGLN1-PTPRF_EGLN1_chr1_231556744_ENST00000366641_PTPRF_chr1_44083116_ENST00000438120_length(transcript)=6054nt_BP=4047nt
TTAGGGGCAGAAAAACATTTGTAATAATTAATGGCTTTGAGAGACACAAGGCTTTGTTTGCCCCAGAGTATTAGTTAACCCACCTAGTGC
TCCTAATCATACAATATTAAGGATTGGGAGGGACATTCATTGCCTCACTCTCTATTTGTTTCACCTTCTGTAAAATTGGTAGAATAATAG
TACCCACTTCATAGCATTGTATGATGATTAAATTGGTTAATATTTTTAAAATGCTTAGAACACAGATTGGGCACATAACAGCAAGCACCA
CATGTGTTTATAAGATAAATTCCTTTGTGTTGCCTTCCGTTAAAGTTTAAATAAGTAAATAAATAAATAAATACTTGCATGACATTTTGA
AGTCTCTCTATAACATCTGAGTAAGTGGCGGCTGCGACAATGCTACTGGAGTTCCAGAATCGTGTTGGTGACAAGATTGTTCACCAGCAT
ATGGTGTGGTGAAAACTCACTAATTTGGAATTAGTTCAGATTATTAAGCCTGAATAGGTGAAAATCCTGAAATCAAGGATCTTTGGAACT
ATTTGAAATCAGTATTTTATATTTTCCTGTTGTATTCATTAAAGTGTTGCAAGTGTTCTATTTGATGGATTAAGTATATTTAGGATATAC
ATGTTCAATTTGTGATTTTGTATACTTAATTGGAACAAGAAAGCTAATAAAGGTTTTGATATGGACATCTATTCTTTTAAGTAAACTTCA
ATGAAAATATATGAGTAGAGCATATAGAGATGTAAATAATTTGTGGACACACCACAGACTGAAATAGCAAATTTAAAAGAAATTGTTGGA
AGAATCAAGTGTTTGTGGAATGAGTCCTCCTAGTAAAGTTCCTGCTCTTGTGAATAATTAAGCCTCATGTATAATTACTATAGCAAAAGG
AAGCCTAAGAAGTATTAGACTCTACTTGTATTTAAATTACATTTTACATAATTTATGTGTATGAAAAATGTTTTAAATGCTTATTTTCGT
AAGCCATGAGATAGCTCCTTTATATTTTAAGAATTTCTGAATTAATTTGCTTGGATTTTATTAGTGCAAATGGCAGAGCTAGCAATTCCT
TTTTCTGTGTTCCCATTCCATCCTATTCATCCCTCTTTTAGGAAACTCTGAACTCTGGATTGTCCTTGTTTACATACCTGCCTCCTGCAT
TGGACTATGTGTCTCTGAGTGTAGTATGACTAATTCATTTGTTTGTCAAGGACTCTCAATGCATTTGTTGAACAGCCTAATTAGTAATGT
CTGCAACAATGACATTTTACTGTATTTAATAAAGCTCTGGGAAAGTAGGATACACATAAGACAGGTCTAGGTCTAAATTCTTTACAGAAA
CTTGGATTTTTAGTTCGGTTTGAAATTTGAAGATGTGAGTATATTTATCTCAGTTTCCCAAAGGACAAGCTAATTGGAATTATCATCCTC
TTTCACTTGATTGGATCCCCAGAATGCCATTTACGCATGCAGCAGGATTTTATAACAGTTTTAAATTCTGTATATTTGATGAAGAGGTTT
TATATTTTTGGATTCAAGCCTCTTTTTAAACTTCTACAATATGGTTTACAATAATTCCTTATATCCTGCTTTTGAAATACATATTACAAC
TTTTTAAGTTTGGAAGGCTATATTTCAAGGACTGAAGTTACAGTATACTCAAGTGATACACAAGCCTAGCACCCCACTTTCCACATAGTG
TTCGATAAAGATTGATAAACTCGAAATCACAGACCTTTTAATTCTTAAGACAAATAGCAGCAGAAAGAAACATCTTTGGCTTATTTCTGG
TAAGGTTTTTATGCTCTGTAAAACAAAGAATTGTATTCATCCGCGCAGCACAGATTCTATTAAAAATAAATGTGAGAGTCGTTAATGTAG
TACTGCTCATTTACCATCAAAATTCACTTTTCAGGAATAATCCCATCAGTTTAAATTGGATATTGGAATGAGCATTGATTACATTTAACT
TGGTAGCCCAAAATTTCTTCATGGGGTTTTGAACTCGGCGGGATTTCAAAGGTTTTAAAAATGAGTTTTTGATTTTTTTTAAAACCCTCA
AATTTCATTACCTTTAAACTAGGTCGAAACGGGGCGCAAGAGATTGGATTAACACCATAGTAATACTTATTTTGTTCTTAACCATTTCAG
GGCTTCTTGAAATAGAGGCTGTATGGTGTAATGGAAAAAACAGCCTTGGAATCTGGGAGCCTGATTCCTGGATTCAGTCCCAGTTTTGCG
TGACCTTGGGCAAGTTACTTTACTTCTCTGAATTTCCGTTTCCTCCTCTGCAAAATGAGGATCGCAATAGCCACCTTGCAACCTTGACTG
GAGCGAGCCTCGCACACCCCGCGCCGGCCTGGAGGAAGAGCAGCCATGATTACGCCGCCTTCGCTCCGCTACCCGCTTGCGGCTGGCGCC
CTCCTCCAGCAGGTGTAGGCGCTGCCGCGCTGCCCCACGCCTTTCCGCCGCTCGCGGGCCTGCGCCTCGGCGTCCCCGAGGAGGCCGCTG
CGGGCTGAGGTAGCGCACCGGCCTCTCGGCGTCCCAGTCCGGTCCCGGGCGGAGGGAAAGCGGGCGACCCACCTCCGAGGCAGAAGCCGA
GGCCCGGCCCCGCCGAGTGCGGAGGAGCGCAGGCAGCCCCCGCCCCTCGGCCCTCCCCCCGGCCCTCCCGGCCCTCCCTCCGCCCCCTCC
GCCCTCGCGCGCCGCCCGCCCGGGTCGCCGCGGGGCCGTGGTGTACGTGCAGAGCGCGCAGAGCGAGTGGCGCCCGTATGCCCTGCGCTC
CTCCACAGCCTGGGCCGGGCCGCCCGGGACGCTGAGGCGGCGGCGGCGGCCGAGGGGGCCGGTCTTGCGCTCCCCAGGCCCGCGCGCCTG
AGCCCAGGTTGCCATTCGCCGCACAGGCCCTATTCTCTCAGCCCTCGGCGGCGATGAGGCGCTGAGGCGGCTGCCGGCGCTGCGCCGGAG
CTTAGGACTCGGAAGCGGCCGGGCCGAGGGCGTGGGGTGCCGGCCTCCCTGAGGCGAGGGTAGCGGGTGCATGGCGCAGTAACGGCCCCT
ATCTCTCTCCCCGCTCCCCAGCCTCGGGCGAGGCCGTCCGGCCGCTACCCCTCCTGCTCGGCCGCCGCAGTCGCCGTCGCCGCCGCCGCC
GCCGCCATGGCCAATGACAGCGGCGGGCCCGGCGGGCCGAGCCCGAGCGAGCGAGACCGGCAGTACTGCGAGCTGTGCGGGAAGATGGAG
AACCTGCTGCGCTGCAGCCGCTGCCGCAGCTCCTTCTACTGCTGCAAGGAGCACCAGCGTCAGGACTGGAAGAAGCACAAGCTCGTGTGC
CAGGGCAGCGAGGGCGCCCTCGGCCACGGAGTGGGCCCACACCAGCATTCCGGCCCCGCGCCGCCGGCTGCAGTGCCGCCGCCCAGGGCC
GGGGCCCGGGAGCCCAGGAAGGCAGCGGCGCGCCGGGACAACGCCTCCGGGGACGCGGCCAAGGGAAAAGTAAAGGCCAAGCCCCCGGCC
GACCCAGCGGCGGCCGCGTCGCCGTGTCGTGCGGCCGCCGGCGGCCAGGGCTCGGCGGTGGCTGCCGAAGCCGAGCCCGGCAAGGAGGAG
CCGCCGGCCCGCTCATCGCTGTTCCAGGAGAAGGCGAACCTGTACCCCCCAAGCAACACGCCCGGGGATGCGCTGAGCCCCGGCGGCGGC
CTGCGGCCCAACGGGCAGACGAAGCCCCTGCCGGCGCTGAAGCTGGCGCTCGAGTACATCGTGCCGTGCATGAACAAGCACGGCATCTGT
GTGGTGGACGACTTCCTCGGCAAGGAGACCGGACAGCAGATCGGCGACGAGGTGCGCGCCCTGCACGACACCGGGAAGTTCACGGACGGG
CAGCTGGTCAGCCAGAAGAGTGACTCGTCCAAGGACATCCGAGGCGATAAGATCACCTGGATCGAGGGCAAGGAGCCCGGCTGCGAAACC
ATTGGGCTGCTCATGAGCAGCATGGACGACCTGATACGCCACTGTAACGGGAAGCTGGGCAGCTACAAAATCAATGGCCGGACGAAATCC
ATCGACCCTGGACAGCAGTTCACGTGGGAGAATTCAAACCTGGAGGTGAACAAGCCCAAGAACCGCTATGCGAATGTCATCGCCTACGAC
CACTCTCGAGTCATCCTTACCTCTATCGATGGCGTCCCCGGGAGTGACTACATCAATGCCAACTACATCGATGGCTACCGCAAGCAGAAT
GCCTACATCGCCACGCAGGGCCCCCTGCCCGAGACCATGGGTGATTTCTGGAGGATGGTGTGGGAACAGCGCACGGCCACTGTGGTCATG
ATGACACGGCTGGAGGAGAAGTCCCGGGTAAAATGTGATCAGTACTGGCCAGCCCGTGGCACCGAGACCTGTGGCCTTATTCAGGTGACC
CTGTTGGACACAGTGGAGCTGGCCACATACACTGTGCGCACCTTCGCACTCCACAAGAGTGGCTCCAGTGAGAAGCGCGAGCTGCGTCAG
TTTCAGTTCATGGCCTGGCCAGACCATGGAGTTCCTGAGTACCCAACTCCCATCCTGGCCTTCCTACGACGGGTCAAGGCCTGCAACCCC
CTAGACGCAGGGCCCATGGTGGTGCACTGCAGCGCGGGCGTGGGCCGCACCGGCTGCTTCATCGTGATTGATGCCATGTTGGAGCGGATG
AAGCACGAGAAGACGGTGGACATCTATGGCCACGTGACCTGCATGCGATCACAGAGGAACTACATGGTGCAGACGGAGGACCAGTACGTG
TTCATCCATGAGGCGCTGCTGGAGGCTGCCACGTGCGGCCACACAGAGGTGCCTGCCCGCAACCTGTATGCCCACATCCAGAAGCTGGGC
CAAGTGCCTCCAGGGGAGAGTGTGACCGCCATGGAGCTCGAGTTCAAGTTGCTGGCCAGCTCCAAGGCCCACACGTCCCGCTTCATCAGC
GCCAACCTGCCCTGCAACAAGTTCAAGAACCGGCTGGTGAACATCATGCCCTACGAATTGACCCGTGTGTGTCTGCAGCCCATCCGTGGT
GTGGAGGGCTCTGACTACATCAATGCCAGCTTCCTGGATGGTTATAGACAGCAGAAGGCCTACATAGCTACACAGGGGCCTCTGGCAGAG
AGCACCGAGGACTTCTGGCGCATGCTATGGGAGCACAATTCCACCATCATCGTCATGCTGACCAAGCTTCGGGAGATGGGCAGGGAGAAA
TGCCACCAGTACTGGCCAGCAGAGCGCTCTGCTCGCTACCAGTACTTTGTTGTTGACCCGATGGCTGAGTACAACATGCCCCAGTATATC
CTGCGTGAGTTCAAGGTCACGGATGCCCGGGATGGGCAGTCAAGGACAATCCGGCAGTTCCAGTTCACAGACTGGCCAGAGCAGGGCGTG
CCCAAGACAGGCGAGGGATTCATTGACTTCATCGGGCAGGTGCATAAGACCAAGGAGCAGTTTGGACAGGATGGGCCTATCACGGTGCAC
TGCAGTGCTGGCGTGGGCCGCACCGGGGTGTTCATCACTCTGAGCATCGTCCTGGAGCGCATGCGCTACGAGGGCGTGGTCGACATGTTT
CAGACCGTGAAGACCCTGCGTACACAGCGTCCTGCCATGGTGCAGACAGAGGACCAGTATCAGCTGTGCTACCGTGCGGCCCTGGAGTAC
CTCGGCAGCTTTGACCACTATGCAACGTAACTACCGCTCCCCTCTCCTCCGCCACCCCCGCCGTGGGGCTCCGGAGGGGACCCAGCTCCT
CTGAGCCATACCGACCATCGTCCAGCCCTCCTACGCAGATGCTGTCACTGGCAGAGCACAGCCCACGGGGATCACAGCGTTTCAGGAACG
TTGCCACACCAATCAGAGAGCCTAGAACATCCCTGGGCAAGTGGATGGCCCAGCAGGCAGGCACTGTGGCCCTTCTGTCCACCAGACCCA
CCTGGAGCCCGCTTCAAGCTCTCTGTTGCGCTCCCGCATTTCTCATGCTTCTTCTCATGGGGTGGGGTTGGGGCAAAGCCTCCTTTTTAA
TACATTAAGTGGGGTAGACTGAGG

>25493_25493_5_EGLN1-PTPRF_EGLN1_chr1_231556744_ENST00000366641_PTPRF_chr1_44083116_ENST00000438120_length(amino acids)=847AA_BP=297
MANDSGGPGGPSPSERDRQYCELCGKMENLLRCSRCRSSFYCCKEHQRQDWKKHKLVCQGSEGALGHGVGPHQHSGPAPPAAVPPPRAGA
REPRKAAARRDNASGDAAKGKVKAKPPADPAAAASPCRAAAGGQGSAVAAEAEPGKEEPPARSSLFQEKANLYPPSNTPGDALSPGGGLR
PNGQTKPLPALKLALEYIVPCMNKHGICVVDDFLGKETGQQIGDEVRALHDTGKFTDGQLVSQKSDSSKDIRGDKITWIEGKEPGCETIG
LLMSSMDDLIRHCNGKLGSYKINGRTKSIDPGQQFTWENSNLEVNKPKNRYANVIAYDHSRVILTSIDGVPGSDYINANYIDGYRKQNAY
IATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPARGTETCGLIQVTLLDTVELATYTVRTFALHKSGSSEKRELRQFQ
FMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFI
HEALLEAATCGHTEVPARNLYAHIQKLGQVPPGESVTAMELEFKLLASSKAHTSRFISANLPCNKFKNRLVNIMPYELTRVCLQPIRGVE
GSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILR
EFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQT
VKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYAT

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Fusion Gene PPI Analysis for EGLN1-PTPRF


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for EGLN1-PTPRF


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for EGLN1-PTPRF


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneEGLN1C1708353Hereditary Paraganglioma-Pheochromocytoma Syndrome6CLINGEN
HgeneEGLN1C1853286Erythrocytosis, Familial, 32CTD_human;GENOMICS_ENGLAND;UNIPROT
HgeneEGLN1C0030421Paraganglioma1GENOMICS_ENGLAND
HgeneEGLN1C0031511Pheochromocytoma1GENOMICS_ENGLAND
HgeneEGLN1C0032461Polycythemia1GENOMICS_ENGLAND
HgeneEGLN1C0149504Encephalopathy, Toxic1CTD_human
HgeneEGLN1C0154659Toxic Encephalitis1CTD_human
HgeneEGLN1C0235032Neurotoxicity Syndromes1CTD_human
HgeneEGLN1C4551683Adrenal Gland Pheochromocytoma1GENOMICS_ENGLAND
TgeneC0024623Malignant neoplasm of stomach1CTD_human
TgeneC0038356Stomach Neoplasms1CTD_human
TgeneC0175755Congenital absent nipple1GENOMICS_ENGLAND
TgeneC0235874Disease Exacerbation1CTD_human
TgeneC0345967Malignant mesothelioma1CTD_human
TgeneC0432357Congenital absence of breast with absent nipple1ORPHANET
TgeneC1708349Hereditary Diffuse Gastric Cancer1CTD_human