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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:ATR-XRN1 (FusionGDB2 ID:HG545TG54464) |
Fusion Gene Summary for ATR-XRN1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: ATR-XRN1 | Fusion gene ID: hg545tg54464 | Hgene | Tgene | Gene symbol | ATR | XRN1 | Gene ID | 545 | 54464 |
| Gene name | ATR serine/threonine kinase | 5'-3' exoribonuclease 1 | |
| Synonyms | FCTCS|FRP1|MEC1|SCKL|SCKL1 | SEP1 | |
| Cytomap | ('ATR')('XRN1') 3q23 | 3q23 | |
| Type of gene | protein-coding | protein-coding | |
| Description | serine/threonine-protein kinase ATRFRAP-related protein-1MEC1, mitosis entry checkpoint 1, homologataxia telangiectasia and Rad3-related protein | 5'-3' exoribonuclease 1strand-exchange protein 1 homolog | |
| Modification date | 20200329 | 20200329 | |
| UniProtAcc | . | . | |
| Ensembl transtripts involved in fusion gene | ENST00000350721, ENST00000383101, | ENST00000350721, ENST00000383101, | |
| Fusion gene scores | * DoF score | 8 X 6 X 6=288 | 5 X 7 X 4=140 |
| # samples | 10 | 8 | |
| ** MAII score | log2(10/288*10)=-1.52606881166759 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(8/140*10)=-0.807354922057604 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: ATR [Title/Abstract] AND XRN1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | ATR(142253922)-XRN1(142123918), # samples:1 | ||
| Anticipated loss of major functional domain due to fusion event. | ATR-XRN1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. ATR-XRN1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. XRN1-ATR seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. XRN1-ATR seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | ATR | GO:0000077 | DNA damage checkpoint | 14657349 |
| Hgene | ATR | GO:0006974 | cellular response to DNA damage stimulus | 27723717|27723720 |
| Hgene | ATR | GO:0018105 | peptidyl-serine phosphorylation | 9733515 |
| Hgene | ATR | GO:0046777 | protein autophosphorylation | 9733515 |
| Hgene | ATR | GO:0071480 | cellular response to gamma radiation | 9925639 |
| Fusion gene breakpoints across ATR (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across XRN1 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | LUSC | TCGA-96-A4JK-01A | ATR | chr3 | 142253922 | - | XRN1 | chr3 | 142123918 | - |
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Fusion Gene ORF analysis for ATR-XRN1 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-intron | ENST00000350721 | ENST00000463916 | ATR | chr3 | 142253922 | - | XRN1 | chr3 | 142123918 | - |
| 5CDS-intron | ENST00000350721 | ENST00000465074 | ATR | chr3 | 142253922 | - | XRN1 | chr3 | 142123918 | - |
| 5CDS-intron | ENST00000350721 | ENST00000544157 | ATR | chr3 | 142253922 | - | XRN1 | chr3 | 142123918 | - |
| 5CDS-intron | ENST00000383101 | ENST00000463916 | ATR | chr3 | 142253922 | - | XRN1 | chr3 | 142123918 | - |
| 5CDS-intron | ENST00000383101 | ENST00000465074 | ATR | chr3 | 142253922 | - | XRN1 | chr3 | 142123918 | - |
| 5CDS-intron | ENST00000383101 | ENST00000544157 | ATR | chr3 | 142253922 | - | XRN1 | chr3 | 142123918 | - |
| In-frame | ENST00000350721 | ENST00000264951 | ATR | chr3 | 142253922 | - | XRN1 | chr3 | 142123918 | - |
| In-frame | ENST00000350721 | ENST00000392981 | ATR | chr3 | 142253922 | - | XRN1 | chr3 | 142123918 | - |
| In-frame | ENST00000383101 | ENST00000264951 | ATR | chr3 | 142253922 | - | XRN1 | chr3 | 142123918 | - |
| In-frame | ENST00000383101 | ENST00000392981 | ATR | chr3 | 142253922 | - | XRN1 | chr3 | 142123918 | - |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000350721 | ATR | chr3 | 142253922 | - | ENST00000264951 | XRN1 | chr3 | 142123918 | - | 12379 | 4067 | 122 | 7474 | 2450 |
| ENST00000350721 | ATR | chr3 | 142253922 | - | ENST00000392981 | XRN1 | chr3 | 142123918 | - | 7689 | 4067 | 122 | 7438 | 2438 |
| ENST00000383101 | ATR | chr3 | 142253922 | - | ENST00000264951 | XRN1 | chr3 | 142123918 | - | 12187 | 3875 | 122 | 7282 | 2386 |
| ENST00000383101 | ATR | chr3 | 142253922 | - | ENST00000392981 | XRN1 | chr3 | 142123918 | - | 7497 | 3875 | 122 | 7246 | 2374 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000350721 | ENST00000264951 | ATR | chr3 | 142253922 | - | XRN1 | chr3 | 142123918 | - | 0.000132583 | 0.99986744 |
| ENST00000350721 | ENST00000392981 | ATR | chr3 | 142253922 | - | XRN1 | chr3 | 142123918 | - | 0.000195985 | 0.9998041 |
| ENST00000383101 | ENST00000264951 | ATR | chr3 | 142253922 | - | XRN1 | chr3 | 142123918 | - | 0.000129378 | 0.99987066 |
| ENST00000383101 | ENST00000392981 | ATR | chr3 | 142253922 | - | XRN1 | chr3 | 142123918 | - | 0.000192308 | 0.99980766 |
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Fusion Genomic Features for ATR-XRN1 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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Fusion Protein Features for ATR-XRN1 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr3:142253922/chr3:142123918) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | . |
| FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. | FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | ATR | chr3:142253922 | chr3:142123918 | ENST00000350721 | - | 21 | 47 | 799_835 | 1315 | 2645.0 | Repeat | Note=HEAT 1 |
| Hgene | ATR | chr3:142253922 | chr3:142123918 | ENST00000383101 | - | 20 | 46 | 799_835 | 1251 | 2581.0 | Repeat | Note=HEAT 1 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | ATR | chr3:142253922 | chr3:142123918 | ENST00000350721 | - | 21 | 47 | 1640_2185 | 1315 | 2645.0 | Domain | FAT |
| Hgene | ATR | chr3:142253922 | chr3:142123918 | ENST00000350721 | - | 21 | 47 | 2322_2567 | 1315 | 2645.0 | Domain | PI3K/PI4K |
| Hgene | ATR | chr3:142253922 | chr3:142123918 | ENST00000350721 | - | 21 | 47 | 2612_2644 | 1315 | 2645.0 | Domain | FATC |
| Hgene | ATR | chr3:142253922 | chr3:142123918 | ENST00000383101 | - | 20 | 46 | 1640_2185 | 1251 | 2581.0 | Domain | FAT |
| Hgene | ATR | chr3:142253922 | chr3:142123918 | ENST00000383101 | - | 20 | 46 | 2322_2567 | 1251 | 2581.0 | Domain | PI3K/PI4K |
| Hgene | ATR | chr3:142253922 | chr3:142123918 | ENST00000383101 | - | 20 | 46 | 2612_2644 | 1251 | 2581.0 | Domain | FATC |
| Hgene | ATR | chr3:142253922 | chr3:142123918 | ENST00000350721 | - | 21 | 47 | 1329_1365 | 1315 | 2645.0 | Repeat | Note=HEAT 2 |
| Hgene | ATR | chr3:142253922 | chr3:142123918 | ENST00000383101 | - | 20 | 46 | 1329_1365 | 1251 | 2581.0 | Repeat | Note=HEAT 2 |
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Fusion Gene Sequence for ATR-XRN1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >8360_8360_1_ATR-XRN1_ATR_chr3_142253922_ENST00000350721_XRN1_chr3_142123918_ENST00000264951_length(transcript)=12379nt_BP=4067nt TTCCGGGAGGAGTTTTGGCCTCCACACGGCTCCGTCGGGCGCCGCGCTCTTCCGGCAGCGGTAGCTTTGGAGACGCCGGGAACCCGCGTT GGCGTGGTTGACTAGTGCCTCGCAGCCTCAGCATGGGGGAACATGGCCTGGAGCTGGCTTCCATGATCCCCGCCCTGCGGGAGCTGGGCA GTGCCACACCAGAGGAATATAATACAGTTGTACAGAAGCCAAGACAAATTCTGTGTCAATTCATTGACCGGATACTTACAGATGTAAATG TTGTTGCTGTAGAACTTGTAAAGAAAACTGACTCTCAGCCAACCTCCGTGATGTTGCTTGATTTCATCCAGCATATCATGAAATCCTCCC CACTTATGTTTGTAAATGTGAGTGGAAGCCATGAGGCCAAAGGCAGTTGTATTGAATTCAGTAATTGGATCATAACGAGACTTCTGCGGA TTGCAGCAACTCCCTCCTGTCATTTGTTACACAAGAAAATCTGTGAAGTCATCTGTTCATTATTATTTCTTTTTAAAAGCAAGAGTCCTG CTATTTTTGGGGTACTCACAAAAGAATTATTACAACTTTTTGAAGACTTGGTTTACCTCCATAGAAGAAATGTGATGGGTCATGCTGTGG AATGGCCAGTGGTCATGAGCCGATTTTTAAGTCAATTAGATGAACACATGGGATATTTACAATCAGCTCCTTTGCAGTTGATGAGTATGC AAAATTTAGAATTTATTGAAGTCACTTTATTAATGGTTCTTACTCGTATTATTGCAATTGTGTTTTTTAGAAGGCAAGAACTCTTACTTT GGCAGATAGGTTGTGTTCTGCTAGAGTATGGTAGTCCAAAAATTAAATCCCTAGCAATTAGCTTTTTAACAGAACTTTTTCAGCTTGGAG GACTACCAGCACAACCAGCTAGCACTTTTTTCAGCTCATTTTTGGAATTATTAAAACACCTTGTAGAAATGGATACTGACCAATTGAAAC TCTATGAAGAGCCATTATCAAAGCTGATAAAGACACTATTTCCCTTTGAAGCAGAAGCTTATAGAAATATTGAACCTGTCTATTTAAATA TGCTGCTGGAAAAACTCTGTGTCATGTTTGAAGACGGTGTGCTCATGCGGCTTAAGTCTGATTTGCTAAAAGCAGCTTTGTGCCATTTAC TGCAGTATTTCCTTAAATTTGTGCCAGCTGGGTATGAATCTGCTTTACAAGTCAGGAAGGTCTATGTGAGAAATATTTGTAAAGCTCTTT TGGATGTGCTTGGAATTGAGGTAGATGCAGAGTACTTGTTGGGCCCACTTTATGCAGCTTTGAAAATGGAAAGTATGGAAATCATTGAGG AGATTCAATGCCAAACTCAACAGGAAAACCTCAGCAGTAATAGTGATGGAATATCACCCAAAAGGCGTCGTCTCAGCTCGTCTCTAAACC CTTCTAAAAGAGCACCAAAACAGACTGAGGAAATTAAACATGTGGACATGAACCAAAAGAGCATATTATGGAGTGCACTGAAACAGAAAG CTGAATCCCTTCAGATTTCCCTTGAATACAGTGGCCTAAAGAATCCTGTTATTGAGATGTTAGAAGGAATTGCTGTTGTCTTACAACTGA CTGCTCTGTGTACTGTTCATTGTTCTCATCAAAACATGAACTGCCGTACTTTCAAGGACTGTCAACATAAATCCAAGAAGAAACCTTCTG TAGTGATAACTTGGATGTCATTGGATTTTTACACAAAAGTGCTTAAGAGCTGTAGAAGTTTGTTAGAATCTGTTCAGAAACTGGACCTGG AGGCAACCATTGATAAGGTGGTGAAAATTTATGATGCTTTGATTTATATGCAAGTAAACAGTTCATTTGAAGATCATATCCTGGAAGATT TATGTGGTATGCTCTCACTTCCATGGATTTATTCCCATTCTGATGATGGCTGTTTAAAGTTGACCACATTTGCCGCTAATCTTCTAACAT TAAGCTGTAGGATTTCAGATAGCTATTCACCACAGGCACAATCACGATGTGTGTTTCTTCTGACTCTGTTTCCAAGAAGAATATTCCTTG AGTGGAGAACAGCAGTTTACAACTGGGCCCTGCAGAGCTCCCATGAAGTAATCCGGGCTAGTTGTGTTAGTGGATTTTTTATCTTATTGC AGCAGCAGAATTCTTGTAACAGAGTTCCCAAGATTCTTATAGATAAAGTCAAAGATGATTCTGACATTGTCAAGAAAGAATTTGCTTCTA TACTTGGTCAACTTGTCTGTACTCTTCACGGCATGTTTTATCTGACAAGTTCTTTAACAGAACCTTTCTCTGAACACGGACATGTGGACC TCTTCTGTAGGAACTTGAAAGCCACTTCTCAACATGAATGTTCATCTTCTCAACTAAAAGCTTCTGTCTGCAAGCCATTCCTTTTCCTAC TGAAAAAAAAAATACCTAGTCCAGTAAAACTTGCTTTCATAGATAATCTACATCATCTTTGTAAGCATCTTGATTTTAGAGAAGATGAAA CAGATGTAAAAGCAGTTCTTGGAACTTTATTAAATTTAATGGAAGATCCAGACAAAGATGTTAGAGTGGCTTTTAGTGGAAATATCAAGC ACATATTGGAATCCTTGGACTCTGAAGATGGATTTATAAAGGAGCTTTTTGTCTTAAGAATGAAGGAAGCATATACACATGCCCAAATAT CAAGAAATAATGAGCTGAAGGATACCTTGATTCTTACAACAGGGGATATTGGAAGGGCCGCAAAAGGAGATTTGGTACCATTTGCACTCT TACACTTATTGCATTGTTTGTTATCCAAGTCAGCATCTGTCTCTGGAGCAGCATACACAGAAATTAGAGCTCTGGTTGCAGCTAAAAGTG TTAAACTGCAAAGTTTTTTCAGCCAGTATAAGAAACCCATCTGTCAGTTTTTGGTAGAATCCCTTCACTCTAGTCAGATGACAGCACTTC CGAATACTCCATGCCAGAATGCTGACGTGCGAAAACAAGATGTGGCTCACCAGAGAGAAATGGCTTTAAATACGTTGTCTGAAATTGCCA ACGTTTTCGACTTTCCTGATCTTAATCGTTTTCTTACTAGGACATTACAAGTTCTACTACCTGATCTTGCTGCCAAAGCAAGCCCTGCAG CTTCTGCTCTCATTCGAACTTTAGGAAAACAATTAAATGTCAATCGTAGAGAGATTTTAATAAACAACTTCAAATATATTTTTTCTCATT TGGTCTGTTCTTGTTCCAAAGATGAATTAGAACGTGCCCTTCATTATCTGAAGAATGAAACAGAAATTGAACTGGGGAGCCTGTTGAGAC AAGATTTCCAAGGATTGCATAATGAATTATTGCTGCGTATTGGAGAACACTATCAACAGGTTTTTAATGGTTTGTCAATACTTGCCTCAT TTGCATCCAGTGATGATCCATATCAGGGCCCGAGAGATATCATATCACCTGAACTGATGGCTGATTATTTACAACCCAAATTGTTGGGCA TTTTGGCTTTTTTTAACATGCAGTTACTGAGCTCTAGTGTTGGCATTGAAGATAAGAAAATGGCCTTGAACAGTTTGATGTCTTTGATGA AGTTAATGGGACCCAAACATGTCAGTTCTGTGAGGGTGAAGATGATGACCACACTGAGAACTGGCCTTCGATTCAAGGATGATTTTCCTG AATTGTGTTGCAGAGCTTGGGACTGCTTTGTTCGCTGCCTGGATCATGCTTGTCTGGGCTCCCTTCTCAGTCATGTAATAGTAGCTTTGT TACCTCTTATACACATCCAGCCTAAAGAAACTGCAGCTATCTTCCACTACCTCATAATTGAAAACAGGGATGCTGTGCAAGATTTTCTTC ATGAAATATATTTTTTACCTGATCATCCAGAATTAAAAAAGATAAAAGCCGTTCTCCAGGAATACAGAAAGGAGACCTCTGAGAGCACTG ATCTTCAGACAACTCTTCAGCTCTCTATGAAGGCCATTCAACATGAAAATGTCGATGTTCGTATTCATGCTCTTACAAGCTTGAAGGAAA CCTTGTATAAAAATCAGAAGCGATTATTGGAAGCCATGGAGACATGTAACCACTCCCTCAAAAAGGAAGAGAGGAAAAGAAACCAACATA GTGAGTGCCTAATGTGCTGGTATGATAGAGACACAGAGTTTATCTATCCTTCTCCATGGCCAGAAAAGTTCCCTGCCATAGAACGATGTT GTACAAGGTATAAAATAATATCCTTAGATGCTTGGCGTGTAGACATAAACAAAAACAAAATAACCAGAATTGACCAGAAAGCATTATATT TCTGTGGATTTCCTACTCTGAAACACATCAGACACAAATTTTTTTTGAAGAAAAGTGGTGTTCAAGTATTCCAGCAAAGCAGTCGTGGAG AAAACATGATGTTGGAAATCTTAGTGGATGCAGAATCAGATGAACTTACCGTAGAAAATGTAGCTTCATCAGTGCTTGGAAAATCTGTCT TTGTTAATTGGCCTCACCTTGAGGAAGCTAGAGTCGTGGCTGTATCAGATGGAGAAACTAAGTTTTACTTGGAAGAACCTCCAGGAACAC AGAAGCTTTATTCAGGAAGAACTGCCCCACCATCTAAAGTGGTTCATCTTGGAGATAAAGAACAATCTAACTGGGCAAAAGAAGTACAAG GAATTTCAGAACACTACCTGAGAAGAAAAGGAATAATAATAAATGAAACATCTGCAGTTGTGTATGCTCAGTTACTCACAGGTCGTAAAT ATCAAATAAATCAAAATGGTGAAGTTCGTCTAGAGAAACAGTGGTCAAAACAAGTTGTTCCTTTTGTTTATCAAACTATTGTCAAGGACA TCCGAGCTTTCGACTCCCGTTTCTCCAATATCAAAACATTGGATGATTTGTTTCCTCTGAGAAGTATGGTCTTTATGCTGGGAACTCCCT ATTATGGCTGCACTGGAGAAGTTCAGGATTCAGGTGATGTGATTACAGAAGGTAGGATTCGTGTGATTTTCAGCATTCCATGTGAACCCA ATCTTGATGCTTTAATACAGAACCAGCATAAATATTCTATAAAGTACAACCCAGGATATGTGTTGGCCAGTCGCCTTGGAGTGAGTGGAT ACCTTGTTTCAAGGTTTACAGGAAGTATTTTTATTGGAAGAGGATCTAGGAGAAACCCTCATGGAGACCATAAAGCAAATGTGGGTTTAA ATCTCAAATTCAACAAGAAAAATGAGGAGGTACCTGGATATACTAAGAAAGTTGGAAGTGAATGGATGTATTCATCTGCAGCAGAACAAC TTCTGGCAGAGTACTTAGAGAGAGCTCCAGAACTATTTAGTTATATAGCCAAAAATAGCCAAGAGGATGTGTTCTATGAAGATGACATTT GGCCTGGAGAAAATGAGAATGGTGCTGAAAAAGTTCAAGAAATTATTACTTGGCTAAAAGGACATCCTGTCAGTACTTTATCTCGTTCTT CTTGTGATTTACAAATTCTGGATGCAGCTATTGTTGAGAAAATTGAGGAAGAAGTCGAAAAGTGCAAGCAAAGAAAGAATAATAAGAAGG TGCGAGTAACAGTGAAACCCCATTTGCTATACAGACCTTTAGAACAGCAACATGGAGTCATTCCTGATCGGGATGCAGAATTTTGTCTTT TTGACCGTGTTGTAAATGTGAGAGAAAACTTCTCAGTTCCAGTTGGCCTTCGAGGCACCATCATAGGAATAAAAGGAGCTAATAGAGAAG CCGATGTACTATTTGAAGTATTATTTGATGAAGAATTTCCTGGAGGGTTAACAATAAGATGCTCACCTGGTAGAGGTTATCGACTGCCAA CAAGTGCCTTGGTGAACCTTTCTCATGGGAGTCGCTCTGAAACTGGAAATCAGAAGTTGACAGCCATCGTAAAACCACAACCAGCTGTAC ATCAACATAGCTCAAGTTCATCAGTTTCCTCTGGGCATTTGGGAGCCCTCAACCATTCCCCTCAATCACTTTTTGTTCCTACTCAAGTAC CTACTAAAGATGATGATGAATTCTGCAACATTTGGCAGTCCTTACAGGGATCTGGAAAGATGCAATACTTTCAGCCAACTATACAAGAGA AGGGTGCAGTTCTACCTCAAGAAATAAGCCAAGTAAATCAACATCATAAATCTGGCTTTAATGACAACAGTGTTAAATATCAGCAAAGAA AACATGACCCTCACAGAAAATTTAAAGAAGAGTGTAAGAGTCCTAAAGCTGAGTGTTGGTCCCAAAAAATGTCCAATAAGCAGCCTAACT CTGGAATTGAGAACTTTTTAGCATCTTTGAATATCTCCAAAGAAAATGAAGTACAGTCATCTCATCATGGGGAGCCTCCAAGTGAAGAGC ATTTGTCACCACAGTCATTTGCCATGGGAACACGGATGCTTAAAGAAATTCTAAAAATTGATGGCTCTAACACTGTGGACCATAAGAATG AAATCAAACAGATTGCTAATGAAATCCCTGTTTCCTCTAACAGAAGAGATGAATATGGATTACCCTCTCAGCCTAAACAAAATAAGAAAT TAGCATCTTATATGAACAAGCCTCACAGTGCTAATGAGTACCATAATGTTCAGTCTATGGACAATATGTGTTGGCCTGCCCCCAGCCAGA TCCCTCCTGTATCCACACCAGTAACTGAACTTTCTCGAATTTGTTCCCTTGTTGGAATGCCACAACCTGATTTCTCCTTTCTTAGGATGC CACAGACAATGACCGTTTGCCAAGTAAAATTATCTAATGGCTTACTGGTACATGGGCCACAGTGCCACTCTGAAAATGAAGCCAAAGAGA AAGCTGCACTTTTTGCTTTACAACAGTTGGGCTCCTTAGGCATGAATTTCCCTTTGCCTTCACAAGTATTTGCAAATTATCCTTCAGCTG TACCACCTGGAACCATTCCTCCAGCCTTTCCCCCACCTACTGGCTGGGATCACTATGGAAGCAACTATGCATTGGGGGCAGCTAATATAA TGCCTTCGTCGTCTCATCTCTTTGGCTCAATGCCATGGGGACCATCGGTGCCAGTTCCTGGGAAGCCCTTCCATCATACTTTATATTCTG GGACCATGCCCATGGCTGGGGGAATACCAGGGGGTGTGCACAATCAGTTTATACCTCTGCAGGTTACTAAAAAAAGGGTTGCAAACAAAA AGAACTTTGAGAATAAGGAAGCCCAGAGTTCTCAAGCCACTCCAGTTCAGACTAGCCAGCCAGATTCTTCCAACATTGTCAAAGTAAGTC CACGGGAGAGCTCATCAGCTTCTTTGAAGTCCTCTCCGATTGCTCAACCTGCATCTTCTTTTCAAGTTGAAACTGCCTCTCAAGGCCATA GTATATCTCACCATAAGTCAACACCAATCTCTTCTTCAAGAAGAAAATCAAGAAAACTGGCTGTTAATTTTGGTGTTTCTAAACCTTCTG AGTAAATTTGGCTCTTAGAATTAAGTTAATTTCTTCTCTTTCCATCTACCTTTTTATAAATACATATCTATGTCTCATAAAAATTAGAAT GTACTATTTTAAAATAATATGTGTAAATTGAAATTTTTTTCATTTTTAAGTTATCAGGCACTTTTCATGCTGTTTAAAAGACTGTGTATC AAATTGTGCACTTTAAGTATGTGCAGTTTGTTGTATGTCAATTATACCTCAATAAATCTGTAATAAAAAACTAAATTAAACCTTGCATTA AAATAATATCACAGTATCAGTGGACTAAACATTAAAATGTACCACTCTAATCATTGGCCTCATGATTGAAGCATCCTGAACTATGAATTA GACATCAGTTAGCAATAATAAGCATTTTTTACACTATCATTGAGGAATAATTACATGGAGCATGAAATTTGGGCCTCCAGTATAACTTAC TGAATGTGGATTTTATTTCTCTTTTTAATGATGTAAGAAAATTGTCAGGAGAATGGCTCTTATTTATGTGTGTTTTAACTTATGCTTTGT TGCCTCTGAGGGTCTTTAGACCTGCTGTGAAAGGATCACATTTGTTGTGGTGCTGCCAGTTTTGCTTTATTCTAAATTTTGTACCAAAGC AACTTTAGAATAATCAGAATATTTCATCTAACTGCTTAGAACTATAAATAGCATTCTAAATTTGAGTAAATACAATTTTTTAGGTTACTC AAGAACCAGCATTAGTAATTTCTAGTAAAATTGTTTCAAAATCTACAGGGTACAATGATTACAAATTAATCTTCTAACAAAATAAAATAT GAAATATTAGTCATGTTAATTAATAAACTGTATTATTTTGTATAGCTTTTTATTTGCTTACCTGACATTTTATGAGAGCTTCATAGTTGG TCGGTATGTAGTGCTTCTTGGGACTGAAGAAATTCTAATTGTTGTTTAAGTTCCAAGGTGTGCTACAATATAGGAGGCACAGTCATCAGT TTGTGACATACATTATTTACTGCCTATTTCATTCTGATTCTATATTTTTAGCTTTATGCTGAACTGTTCAATGATGCTGGGATTCTCTCT TTGCATGTCATATGTGAATGTGTGGTTCAAGCTGTAACTGTTGAAATTATTTTAGAATTTATGACGATTTCTCAGCAGGGCCTATGTTTA TATATATATATATATTTATTCTTTAGTTTTTGTGATATGCTTATATTTTTAAGGAAGTAAGTTATAGCATACTTTTTTAAAAGTAGGAAC CACAATCTTTATATGGAGCAGCTTGTTATATCTGATTTTCATGTAACTCATTGGAAACTCTGCCATGACTCTTAAAGTAGTCTTACTTGT TTTTTAAAATGCTGGTATTAAACTAAATGGACTCCTTTCACTAACTGCTGATTTCAGAGTTTAAATGTTAGCAGGATATTTGTGTATTAG CAGTGCCTTCAGTATAAGAGAGAAATATTCATTATCTGTCATTTATCATAGTCGTATAAGTTTCCATGATTTTATTTTCTGTTATTTTCA TAAGTTCAGATGTTTATCAGTTCCCAACATTGTTTCTTTATCTGTAGTGGGATCTTGAGTAATGAGGCTCAAGTAAATCCTCAATGTGTA TAATTATTGCCTCATAAACTCTCTCTTTGTTTTTAAAGGAAACATCTATTATGGTAATACAAAGAAAAGTTAAATTGTGACAGTAATGTT ATATTAACCTCTTCCTACTTTAAAGTGTGAAATGTTTCACCTCAGCTGTACAAACTCCAGCATTGAGAATTTGCCTCACTCATTACTCCT GTGTGACAGTTATATAAATAGCATGCAGCTCACATCTGTTTTAGAGCATAGAAGAAGCGGCACCTGCCATCTTCTGAAAACTCCAAAGGG AAATTTCAGTAGACATAGTGCACTAAACCCATAAGGATACTTGACCAATATTTGAGCACAGCAAGCTGACAGTTCTATACAGATAGGCAG TGAAAGAGTTTTATTTTCCAGCCAGGCGCAGTGGCTCAAATCCCAGCACTTCGGGAGGCTAAGGCAGGCGGATCACTTGAGGTCCGGAGT TCCAGACAAGCCTGGCCAACATGATGAAGCCCTGTCTCTACTAAAAATACAAAAATTAGCCGGGCGTGATGGCACATGCCTTTAGTCCCA GCTACTCGGGAGGCTGAGGCATGAGAATCATTTGAACCCGCGAGGCAGAGTCTGCAGTGAGCCGAGATTGCACCACTGCACTCCAGCCTG GAGAGCAGAGCAAGACTCTGTCTCAAAAAAAAGAAAAAAGTTTTATTATCCTTACTTTTTTTTTAACATTATTATTCTAAAGGTCAAAAC TGAGAAGAGATTAAGATAGGAGAGAGCTCCATAATGGCTGGATAGTGGTCAGGCATTCTCTATTCTTTTCCCCCTGTAGACCCATTCTAA ATGTGGGCCTGAGGTCAATGGGAGATGTGCCCTCCCTATGGAGGATGTAAGAAGCAGAGGCCATTTCTGCCCCATGTTGAGGAAACAATC TGTTGATAGACCTGGAATTTAGAGTATATCTGAAAAGCAGTTGGACTTCAAGAAATTTAAAATTCTCTCTTTGAGATGGGGTGGACTAAG ACCACCCCCAAAGTTTAAAAATATGCTCATTCAACTTGAATCTTCTGAGGACTTTTTGTGAAAATGGTGGACTGTTTAGGGCATAGGACA GATTCCCCAAATTGCTTTATGCTTCCACATAACTAGAGCACTTCAATCTATTTAAGCCTTTGTCTCCTAACTGAAACATTATTTCTAAAT ATTTCTATTCAATAAGTTTTTTCTTTTTTGAGCAACTTAAGTGAATTTTGAAGATTGCTCCTTCCAGTCTCGTTCCTTTTCACATTTTCC TGCATTACCTAATAATTACCTCAGCGTTAGAATTTGAATGTATTAATTGATTTAAACATCATGTAGACTAAAGTCTTAAACATCTAAGAC TCAGTTGTAGTTGCAGAAAAAAATTAAAGTCACCTCTACTGAACCTTGGTTTCAATTTAAGATTTTTCTTGCTTTTCAAAGGGGTAACTA ATAAAGATTGAAGGGTTTTTTTCCCGATTGGTGGAGGAATGAAGAACTATTGATGCAAGTTTTTTTATTGTTTCTTTCTATGATCAGGTA CCTGCTTTCATTTTAGACTGCTACTTCCAAACTAAGCTAGATTCTTGGTTTTAATGAGAGGAGGCAGAGAGAGGGAGGCAGATGGAAGAA GAAAAACAGTTAAATAAGACATACCCAGTCACTGCATTTTTGGACTATACCGTATCTTTCTAGCACAAGGAAATAGATAAACTGTAAGGT CTTTTTTACTCACTTTTTATTTATGTGTTCTATTTGTGTTAGTCATAACTGTTTATAGTGGTTGTCTAATTTTTACTTTTATTATATGAG ATAGAGCTGTGCAGATCTTCACTCAAGTTAGTTCTGTCACGCTTCTTCCCATTATTTAGAGCACAGTTTTTTAAAGCAACTGTACAATTT CTCAGCCTTATGAGCTTGCTGTATTTCTTGGTATCATGTTGCTTCCAAATTTTGTTTTTACTGTAGAAGACAATTAATTTATTGTAGAGA AGTGGCTGTGAAAGTCGTTCTCTGTCTTTAAAAATCAATTGCAGAAGTTCATTTGTCATTTTTCTAGAGATAAATTATAGTACTCAAACT GGCAGTGCTCAGTATATACATTTTGTAAGCTTTGTCAGTGAAACCATCAGTTTTGCAGGAGCTTCCTTTCCTAGTCAAGATAAAGCTTAA AATTCCAGAAATTAATGTCGTTCGGACTGACTTTATTCATATTTCCATCAAACTTCTCCAATACAGTAAGAGATAGTGTTGAACCAGCAT CAAGTCTCCAGAAACATGGCAGAGCAGACAGGCCGTTAAGTTTCACAGACATCATAGATCCTTTTCTTAAAGAAGAAAAACATGTATAAA ATAGTTTTAGTAGTCCAAAATGTCAACTATCTGTAGCTGCTTTTGTGTGTGTGTCAGTGAACAAATAATAATGCCTTGCTCAATCAATGC ATTCAGCCATCTCAAGTGCAATTTGTGAAGGAGACTATGGTTTCCAAAAGATACATTTTTTTACAAAGTTAAACCTGTAAAAAGTCTTTT TTTTTTTCCCTCCAGCCGTACACCAACTGCACTTGGTTGTTTCAGCAGTTGGTATACTATTAAATTGTCCAGGCCAAATAGGTTTCTGTA GCTGTTTTAGTAATTTGAAGCCAAATTCTCATGCTGTTTCTCATTAAAAAGAATGAGAATTTGGTCCATAGTTAGCTTTAAGTTCTCTCT TCCTTTCTTTCCCTTACAGTTAAGGGTTTGGTGGGGGATGGGGAGGTTGTTTTCGTTTTTTGGATTTTTTTGTCTTTTGGCTTTAAGTAT CATATTTTCTTTTGCCTGTATCCAACTGCTTCTTTGAGTATTTTCATCTAGTTTAATGTGAGTAATAGATGCTGTGCTGTCATTGAAGTG TTCAACATTTTGTTCATTTAAACAAAAGTGTAATTCATACATATATAGATACATATCTTAATTGATTTCTCAACTATTTTATAAGTAACT GGAATTTTTCATTAGATCTTATACAGAGAAGTATTTTATTAAAAATTCAAAAGGGAAGACTTTTATGTGCTCATTTTGTAATTTTTGATT TTAAATATCTTTACATTGTCTGCCAATTAAAGTGTTTTAAACTTGCATTGGAATGGACTCCGAATGTATTTTTGTGGTGTTACGTTATCC GTAGATTTCTAGCATGAAGTTAGCCTCACGATGCTGTGCAAAGGATTTTAAAATATGAGAGTCACTGAAAGAGTTTAAACATCTGTTCAT >8360_8360_1_ATR-XRN1_ATR_chr3_142253922_ENST00000350721_XRN1_chr3_142123918_ENST00000264951_length(amino acids)=2450AA_BP=0 MGEHGLELASMIPALRELGSATPEEYNTVVQKPRQILCQFIDRILTDVNVVAVELVKKTDSQPTSVMLLDFIQHIMKSSPLMFVNVSGSH EAKGSCIEFSNWIITRLLRIAATPSCHLLHKKICEVICSLLFLFKSKSPAIFGVLTKELLQLFEDLVYLHRRNVMGHAVEWPVVMSRFLS QLDEHMGYLQSAPLQLMSMQNLEFIEVTLLMVLTRIIAIVFFRRQELLLWQIGCVLLEYGSPKIKSLAISFLTELFQLGGLPAQPASTFF SSFLELLKHLVEMDTDQLKLYEEPLSKLIKTLFPFEAEAYRNIEPVYLNMLLEKLCVMFEDGVLMRLKSDLLKAALCHLLQYFLKFVPAG YESALQVRKVYVRNICKALLDVLGIEVDAEYLLGPLYAALKMESMEIIEEIQCQTQQENLSSNSDGISPKRRRLSSSLNPSKRAPKQTEE IKHVDMNQKSILWSALKQKAESLQISLEYSGLKNPVIEMLEGIAVVLQLTALCTVHCSHQNMNCRTFKDCQHKSKKKPSVVITWMSLDFY TKVLKSCRSLLESVQKLDLEATIDKVVKIYDALIYMQVNSSFEDHILEDLCGMLSLPWIYSHSDDGCLKLTTFAANLLTLSCRISDSYSP QAQSRCVFLLTLFPRRIFLEWRTAVYNWALQSSHEVIRASCVSGFFILLQQQNSCNRVPKILIDKVKDDSDIVKKEFASILGQLVCTLHG MFYLTSSLTEPFSEHGHVDLFCRNLKATSQHECSSSQLKASVCKPFLFLLKKKIPSPVKLAFIDNLHHLCKHLDFREDETDVKAVLGTLL NLMEDPDKDVRVAFSGNIKHILESLDSEDGFIKELFVLRMKEAYTHAQISRNNELKDTLILTTGDIGRAAKGDLVPFALLHLLHCLLSKS ASVSGAAYTEIRALVAAKSVKLQSFFSQYKKPICQFLVESLHSSQMTALPNTPCQNADVRKQDVAHQREMALNTLSEIANVFDFPDLNRF LTRTLQVLLPDLAAKASPAASALIRTLGKQLNVNRREILINNFKYIFSHLVCSCSKDELERALHYLKNETEIELGSLLRQDFQGLHNELL LRIGEHYQQVFNGLSILASFASSDDPYQGPRDIISPELMADYLQPKLLGILAFFNMQLLSSSVGIEDKKMALNSLMSLMKLMGPKHVSSV RVKMMTTLRTGLRFKDDFPELCCRAWDCFVRCLDHACLGSLLSHVIVALLPLIHIQPKETAAIFHYLIIENRDAVQDFLHEIYFLPDHPE LKKIKAVLQEYRKETSESTDLQTTLQLSMKAIQHENVDVRIHALTSLKETLYKNQKRLLEAMETCNHSLKKEERKRNQHSECLMCWYDRD TEFIYPSPWPEKFPAIERCCTRYKIISLDAWRVDINKNKITRIDQKALYFCGFPTLKHIRHKFFLKKSGVQVFQQSSRGENMMLEILVDA ESDELTVENVASSVLGKSVFVNWPHLEEARVVAVSDGETKFYLEEPPGTQKLYSGRTAPPSKVVHLGDKEQSNWAKEVQGISEHYLRRKG IIINETSAVVYAQLLTGRKYQINQNGEVRLEKQWSKQVVPFVYQTIVKDIRAFDSRFSNIKTLDDLFPLRSMVFMLGTPYYGCTGEVQDS GDVITEGRIRVIFSIPCEPNLDALIQNQHKYSIKYNPGYVLASRLGVSGYLVSRFTGSIFIGRGSRRNPHGDHKANVGLNLKFNKKNEEV PGYTKKVGSEWMYSSAAEQLLAEYLERAPELFSYIAKNSQEDVFYEDDIWPGENENGAEKVQEIITWLKGHPVSTLSRSSCDLQILDAAI VEKIEEEVEKCKQRKNNKKVRVTVKPHLLYRPLEQQHGVIPDRDAEFCLFDRVVNVRENFSVPVGLRGTIIGIKGANREADVLFEVLFDE EFPGGLTIRCSPGRGYRLPTSALVNLSHGSRSETGNQKLTAIVKPQPAVHQHSSSSSVSSGHLGALNHSPQSLFVPTQVPTKDDDEFCNI WQSLQGSGKMQYFQPTIQEKGAVLPQEISQVNQHHKSGFNDNSVKYQQRKHDPHRKFKEECKSPKAECWSQKMSNKQPNSGIENFLASLN ISKENEVQSSHHGEPPSEEHLSPQSFAMGTRMLKEILKIDGSNTVDHKNEIKQIANEIPVSSNRRDEYGLPSQPKQNKKLASYMNKPHSA NEYHNVQSMDNMCWPAPSQIPPVSTPVTELSRICSLVGMPQPDFSFLRMPQTMTVCQVKLSNGLLVHGPQCHSENEAKEKAALFALQQLG SLGMNFPLPSQVFANYPSAVPPGTIPPAFPPPTGWDHYGSNYALGAANIMPSSSHLFGSMPWGPSVPVPGKPFHHTLYSGTMPMAGGIPG GVHNQFIPLQVTKKRVANKKNFENKEAQSSQATPVQTSQPDSSNIVKVSPRESSSASLKSSPIAQPASSFQVETASQGHSISHHKSTPIS -------------------------------------------------------------- >8360_8360_2_ATR-XRN1_ATR_chr3_142253922_ENST00000350721_XRN1_chr3_142123918_ENST00000392981_length(transcript)=7689nt_BP=4067nt TTCCGGGAGGAGTTTTGGCCTCCACACGGCTCCGTCGGGCGCCGCGCTCTTCCGGCAGCGGTAGCTTTGGAGACGCCGGGAACCCGCGTT GGCGTGGTTGACTAGTGCCTCGCAGCCTCAGCATGGGGGAACATGGCCTGGAGCTGGCTTCCATGATCCCCGCCCTGCGGGAGCTGGGCA GTGCCACACCAGAGGAATATAATACAGTTGTACAGAAGCCAAGACAAATTCTGTGTCAATTCATTGACCGGATACTTACAGATGTAAATG TTGTTGCTGTAGAACTTGTAAAGAAAACTGACTCTCAGCCAACCTCCGTGATGTTGCTTGATTTCATCCAGCATATCATGAAATCCTCCC CACTTATGTTTGTAAATGTGAGTGGAAGCCATGAGGCCAAAGGCAGTTGTATTGAATTCAGTAATTGGATCATAACGAGACTTCTGCGGA TTGCAGCAACTCCCTCCTGTCATTTGTTACACAAGAAAATCTGTGAAGTCATCTGTTCATTATTATTTCTTTTTAAAAGCAAGAGTCCTG CTATTTTTGGGGTACTCACAAAAGAATTATTACAACTTTTTGAAGACTTGGTTTACCTCCATAGAAGAAATGTGATGGGTCATGCTGTGG AATGGCCAGTGGTCATGAGCCGATTTTTAAGTCAATTAGATGAACACATGGGATATTTACAATCAGCTCCTTTGCAGTTGATGAGTATGC AAAATTTAGAATTTATTGAAGTCACTTTATTAATGGTTCTTACTCGTATTATTGCAATTGTGTTTTTTAGAAGGCAAGAACTCTTACTTT GGCAGATAGGTTGTGTTCTGCTAGAGTATGGTAGTCCAAAAATTAAATCCCTAGCAATTAGCTTTTTAACAGAACTTTTTCAGCTTGGAG GACTACCAGCACAACCAGCTAGCACTTTTTTCAGCTCATTTTTGGAATTATTAAAACACCTTGTAGAAATGGATACTGACCAATTGAAAC TCTATGAAGAGCCATTATCAAAGCTGATAAAGACACTATTTCCCTTTGAAGCAGAAGCTTATAGAAATATTGAACCTGTCTATTTAAATA TGCTGCTGGAAAAACTCTGTGTCATGTTTGAAGACGGTGTGCTCATGCGGCTTAAGTCTGATTTGCTAAAAGCAGCTTTGTGCCATTTAC TGCAGTATTTCCTTAAATTTGTGCCAGCTGGGTATGAATCTGCTTTACAAGTCAGGAAGGTCTATGTGAGAAATATTTGTAAAGCTCTTT TGGATGTGCTTGGAATTGAGGTAGATGCAGAGTACTTGTTGGGCCCACTTTATGCAGCTTTGAAAATGGAAAGTATGGAAATCATTGAGG AGATTCAATGCCAAACTCAACAGGAAAACCTCAGCAGTAATAGTGATGGAATATCACCCAAAAGGCGTCGTCTCAGCTCGTCTCTAAACC CTTCTAAAAGAGCACCAAAACAGACTGAGGAAATTAAACATGTGGACATGAACCAAAAGAGCATATTATGGAGTGCACTGAAACAGAAAG CTGAATCCCTTCAGATTTCCCTTGAATACAGTGGCCTAAAGAATCCTGTTATTGAGATGTTAGAAGGAATTGCTGTTGTCTTACAACTGA CTGCTCTGTGTACTGTTCATTGTTCTCATCAAAACATGAACTGCCGTACTTTCAAGGACTGTCAACATAAATCCAAGAAGAAACCTTCTG TAGTGATAACTTGGATGTCATTGGATTTTTACACAAAAGTGCTTAAGAGCTGTAGAAGTTTGTTAGAATCTGTTCAGAAACTGGACCTGG AGGCAACCATTGATAAGGTGGTGAAAATTTATGATGCTTTGATTTATATGCAAGTAAACAGTTCATTTGAAGATCATATCCTGGAAGATT TATGTGGTATGCTCTCACTTCCATGGATTTATTCCCATTCTGATGATGGCTGTTTAAAGTTGACCACATTTGCCGCTAATCTTCTAACAT TAAGCTGTAGGATTTCAGATAGCTATTCACCACAGGCACAATCACGATGTGTGTTTCTTCTGACTCTGTTTCCAAGAAGAATATTCCTTG AGTGGAGAACAGCAGTTTACAACTGGGCCCTGCAGAGCTCCCATGAAGTAATCCGGGCTAGTTGTGTTAGTGGATTTTTTATCTTATTGC AGCAGCAGAATTCTTGTAACAGAGTTCCCAAGATTCTTATAGATAAAGTCAAAGATGATTCTGACATTGTCAAGAAAGAATTTGCTTCTA TACTTGGTCAACTTGTCTGTACTCTTCACGGCATGTTTTATCTGACAAGTTCTTTAACAGAACCTTTCTCTGAACACGGACATGTGGACC TCTTCTGTAGGAACTTGAAAGCCACTTCTCAACATGAATGTTCATCTTCTCAACTAAAAGCTTCTGTCTGCAAGCCATTCCTTTTCCTAC TGAAAAAAAAAATACCTAGTCCAGTAAAACTTGCTTTCATAGATAATCTACATCATCTTTGTAAGCATCTTGATTTTAGAGAAGATGAAA CAGATGTAAAAGCAGTTCTTGGAACTTTATTAAATTTAATGGAAGATCCAGACAAAGATGTTAGAGTGGCTTTTAGTGGAAATATCAAGC ACATATTGGAATCCTTGGACTCTGAAGATGGATTTATAAAGGAGCTTTTTGTCTTAAGAATGAAGGAAGCATATACACATGCCCAAATAT CAAGAAATAATGAGCTGAAGGATACCTTGATTCTTACAACAGGGGATATTGGAAGGGCCGCAAAAGGAGATTTGGTACCATTTGCACTCT TACACTTATTGCATTGTTTGTTATCCAAGTCAGCATCTGTCTCTGGAGCAGCATACACAGAAATTAGAGCTCTGGTTGCAGCTAAAAGTG TTAAACTGCAAAGTTTTTTCAGCCAGTATAAGAAACCCATCTGTCAGTTTTTGGTAGAATCCCTTCACTCTAGTCAGATGACAGCACTTC CGAATACTCCATGCCAGAATGCTGACGTGCGAAAACAAGATGTGGCTCACCAGAGAGAAATGGCTTTAAATACGTTGTCTGAAATTGCCA ACGTTTTCGACTTTCCTGATCTTAATCGTTTTCTTACTAGGACATTACAAGTTCTACTACCTGATCTTGCTGCCAAAGCAAGCCCTGCAG CTTCTGCTCTCATTCGAACTTTAGGAAAACAATTAAATGTCAATCGTAGAGAGATTTTAATAAACAACTTCAAATATATTTTTTCTCATT TGGTCTGTTCTTGTTCCAAAGATGAATTAGAACGTGCCCTTCATTATCTGAAGAATGAAACAGAAATTGAACTGGGGAGCCTGTTGAGAC AAGATTTCCAAGGATTGCATAATGAATTATTGCTGCGTATTGGAGAACACTATCAACAGGTTTTTAATGGTTTGTCAATACTTGCCTCAT TTGCATCCAGTGATGATCCATATCAGGGCCCGAGAGATATCATATCACCTGAACTGATGGCTGATTATTTACAACCCAAATTGTTGGGCA TTTTGGCTTTTTTTAACATGCAGTTACTGAGCTCTAGTGTTGGCATTGAAGATAAGAAAATGGCCTTGAACAGTTTGATGTCTTTGATGA AGTTAATGGGACCCAAACATGTCAGTTCTGTGAGGGTGAAGATGATGACCACACTGAGAACTGGCCTTCGATTCAAGGATGATTTTCCTG AATTGTGTTGCAGAGCTTGGGACTGCTTTGTTCGCTGCCTGGATCATGCTTGTCTGGGCTCCCTTCTCAGTCATGTAATAGTAGCTTTGT TACCTCTTATACACATCCAGCCTAAAGAAACTGCAGCTATCTTCCACTACCTCATAATTGAAAACAGGGATGCTGTGCAAGATTTTCTTC ATGAAATATATTTTTTACCTGATCATCCAGAATTAAAAAAGATAAAAGCCGTTCTCCAGGAATACAGAAAGGAGACCTCTGAGAGCACTG ATCTTCAGACAACTCTTCAGCTCTCTATGAAGGCCATTCAACATGAAAATGTCGATGTTCGTATTCATGCTCTTACAAGCTTGAAGGAAA CCTTGTATAAAAATCAGAAGCGATTATTGGAAGCCATGGAGACATGTAACCACTCCCTCAAAAAGGAAGAGAGGAAAAGAAACCAACATA GTGAGTGCCTAATGTGCTGGTATGATAGAGACACAGAGTTTATCTATCCTTCTCCATGGCCAGAAAAGTTCCCTGCCATAGAACGATGTT GTACAAGGTATAAAATAATATCCTTAGATGCTTGGCGTGTAGACATAAACAAAAACAAAATAACCAGAATTGACCAGAAAGCATTATATT TCTGTGGATTTCCTACTCTGAAACACATCAGACACAAATTTTTTTTGAAGAAAAGTGGTGTTCAAGTATTCCAGCAAAGCAGTCGTGGAG AAAACATGATGTTGGAAATCTTAGTGGATGCAGAATCAGATGAACTTACCGTAGAAAATGTAGCTTCATCAGTGCTTGGAAAATCTGTCT TTGTTAATTGGCCTCACCTTGAGGAAGCTAGAGTCGTGGCTGTATCAGATGGAGAAACTAAGTTTTACTTGGAAGAACCTCCAGGAACAC AGAAGCTTTATTCAGGAAGAACTGCCCCACCATCTAAAGTGGTTCATCTTGGAGATAAAGAACAATCTAACTGGGCAAAAGAAGTACAAG GAATTTCAGAACACTACCTGAGAAGAAAAGGAATAATAATAAATGAAACATCTGCAGTTGTGTATGCTCAGTTACTCACAGGTCGTAAAT ATCAAATAAATCAAAATGGTGAAGTTCGTCTAGAGAAACAGTGGTCAAAACAAGTTGTTCCTTTTGTTTATCAAACTATTGTCAAGGACA TCCGAGCTTTCGACTCCCGTTTCTCCAATATCAAAACATTGGATGATTTGTTTCCTCTGAGAAGTATGGTCTTTATGCTGGGAACTCCCT ATTATGGCTGCACTGGAGAAGTTCAGGATTCAGGTGATGTGATTACAGAAGGTAGGATTCGTGTGATTTTCAGCATTCCATGTGAACCCA ATCTTGATGCTTTAATACAGAACCAGCATAAATATTCTATAAAGTACAACCCAGGATATGTGTTGGCCAGTCGCCTTGGAGTGAGTGGAT ACCTTGTTTCAAGGTTTACAGGAAGTATTTTTATTGGAAGAGGATCTAGGAGAAACCCTCATGGAGACCATAAAGCAAATGTGGGTTTAA ATCTCAAATTCAACAAGAAAAATGAGGAGGTACCTGGATATACTAAGAAAGTTGGAAGTGAATGGATGTATTCATCTGCAGCAGAACAAC TTCTGGCAGAGTACTTAGAGAGAGCTCCAGAACTATTTAGTTATATAGCCAAAAATAGCCAAGAGGATGTGTTCTATGAAGATGACATTT GGCCTGGAGAAAATGAGAATGGTGCTGAAAAAGTTCAAGAAATTATTACTTGGCTAAAAGGACATCCTGTCAGTACTTTATCTCGTTCTT CTTGTGATTTACAAATTCTGGATGCAGCTATTGTTGAGAAAATTGAGGAAGAAGTCGAAAAGTGCAAGCAAAGAAAGAATAATAAGAAGG TGCGAGTAACAGTGAAACCCCATTTGCTATACAGACCTTTAGAACAGCAACATGGAGTCATTCCTGATCGGGATGCAGAATTTTGTCTTT TTGACCGTGTTGTAAATGTGAGAGAAAACTTCTCAGTTCCAGTTGGCCTTCGAGGCACCATCATAGGAATAAAAGGAGCTAATAGAGAAG CCGATGTACTATTTGAAGTATTATTTGATGAAGAATTTCCTGGAGGGTTAACAATAAGATGCTCACCTGGTAGAGGTTATCGACTGCCAA CAAGTGCCTTGGTGAACCTTTCTCATGGGAGTCGCTCTGAAACTGGAAATCAGAAGTTGACAGCCATCGTAAAACCACAACCAGCTGTAC ATCAACATAGCTCAAGTTCATCAGTTTCCTCTGGGCATTTGGGAGCCCTCAACCATTCCCCTCAATCACTTTTTGTTCCTACTCAAGTAC CTACTAAAGATGATGATGAATTCTGCAACATTTGGCAGTCCTTACAGGGATCTGGAAAGATGCAATACTTTCAGCCAACTATACAAGAGA AGGGTGCAGTTCTACCTCAAGAAATAAGCCAAGTAAATCAACATCATAAATCTGGCTTTAATGACAACAGTGTTAAATATCAGCAAAGAA AACATGACCCTCACAGAAAATTTAAAGAAGAGTGTAAGAGTCCTAAAGCTGAGTGTTGGTCCCAAAAAATGTCCAATAAGCAGCCTAACT CTGGAATTGAGAACTTTTTAGCATCTTTGAATATCTCCAAAGAAAATGAAGTACAGTCATCTCATCATGGGGAGCCTCCAAGTGAAGAGC ATTTGTCACCACAGTCATTTGCCATGAAGGGAACACGGATGCTTAAAGAAATTCTAAAAATTGATGGCTCTAACACTGTGGACCATAAGA ATGAAATCAAACAGATTGCTAATGAAATCCCTGTTTCCTCTAACAGAAGAGATGAATATGGATTACCCTCTCAGCCTAAACAAAATAAGA AATTAGCATCTTATATGAACAAGCCTCACAGTGCTAATGAGTACCATAATGTTCAGTCTATGGACAATATGTGTTGGCCTGCCCCCAGCC AGATCCCTCCTGTATCCACACCAGTAACTGAACTTTCTCGAATTTGTTCCCTTGTTGGAATGCCACAACCTGATTTCTCCTTTCTTAGGA TGCCACAGACAATGACCGTTTGCCAAGTAAAATTATCTAATGGCTTACTGGTACATGGGCCACAGTGCCACTCTGAAAATGAAGCCAAAG AGAAAGCTGCACTTTTTGCTTTACAACAGTTGGGCTCCTTAGGCATGAATTTCCCTTTGCCTTCACAAGTATTTGCAAATTATCCTTCAG CTGTACCACCTGGAACCATTCCTCCAGCCTTTCCCCCACCTACTGCTAATATAATGCCTTCGTCGTCTCATCTCTTTGGCTCAATGCCAT GGGGACCATCGGTGCCAGTTCCTGGGAAGCCCTTCCATCATACTTTATATTCTGGGACCATGCCCATGGCTGGGGGAATACCAGGGGGTG TGCACAATCAGTTTATACCTCTGCAGGTTACTAAAAAAAGGGTTGCAAACAAAAAGAACTTTGAGAATAAGGAAGCCCAGAGTTCTCAAG CCACTCCAGTTCAGACTAGCCAGCCAGATTCTTCCAACATTGTCAAAGTAAGTCCACGGGAGAGCTCATCAGCTTCTTTGAAGTCCTCTC CGATTGCTCAACCTGCATCTTCTTTTCAAGTTGAAACTGCCTCTCAAGGCCATAGTATATCTCACCATAAGTCAACACCAATCTCTTCTT CAAGAAGAAAATCAAGAAAACTGGCTGTTAATTTTGGTGTTTCTAAACCTTCTGAGTAAATTTGGCTCTTAGAATTAAGTTAATTTCTTC TCTTTCCATCTACCTTTTTATAAATACATATCTATGTCTCATAAAAATTAGAATGTACTATTTTAAAATAATATGTGTAAATTGAAATTT TTTTCATTTTTAAGTTATCAGGCACTTTTCATGCTGTTTAAAAGACTGTGTATCAAATTGTGCACTTTAAGTATGTGCAGTTTGTTGTAT >8360_8360_2_ATR-XRN1_ATR_chr3_142253922_ENST00000350721_XRN1_chr3_142123918_ENST00000392981_length(amino acids)=2438AA_BP=0 MGEHGLELASMIPALRELGSATPEEYNTVVQKPRQILCQFIDRILTDVNVVAVELVKKTDSQPTSVMLLDFIQHIMKSSPLMFVNVSGSH EAKGSCIEFSNWIITRLLRIAATPSCHLLHKKICEVICSLLFLFKSKSPAIFGVLTKELLQLFEDLVYLHRRNVMGHAVEWPVVMSRFLS QLDEHMGYLQSAPLQLMSMQNLEFIEVTLLMVLTRIIAIVFFRRQELLLWQIGCVLLEYGSPKIKSLAISFLTELFQLGGLPAQPASTFF SSFLELLKHLVEMDTDQLKLYEEPLSKLIKTLFPFEAEAYRNIEPVYLNMLLEKLCVMFEDGVLMRLKSDLLKAALCHLLQYFLKFVPAG YESALQVRKVYVRNICKALLDVLGIEVDAEYLLGPLYAALKMESMEIIEEIQCQTQQENLSSNSDGISPKRRRLSSSLNPSKRAPKQTEE IKHVDMNQKSILWSALKQKAESLQISLEYSGLKNPVIEMLEGIAVVLQLTALCTVHCSHQNMNCRTFKDCQHKSKKKPSVVITWMSLDFY TKVLKSCRSLLESVQKLDLEATIDKVVKIYDALIYMQVNSSFEDHILEDLCGMLSLPWIYSHSDDGCLKLTTFAANLLTLSCRISDSYSP QAQSRCVFLLTLFPRRIFLEWRTAVYNWALQSSHEVIRASCVSGFFILLQQQNSCNRVPKILIDKVKDDSDIVKKEFASILGQLVCTLHG MFYLTSSLTEPFSEHGHVDLFCRNLKATSQHECSSSQLKASVCKPFLFLLKKKIPSPVKLAFIDNLHHLCKHLDFREDETDVKAVLGTLL NLMEDPDKDVRVAFSGNIKHILESLDSEDGFIKELFVLRMKEAYTHAQISRNNELKDTLILTTGDIGRAAKGDLVPFALLHLLHCLLSKS ASVSGAAYTEIRALVAAKSVKLQSFFSQYKKPICQFLVESLHSSQMTALPNTPCQNADVRKQDVAHQREMALNTLSEIANVFDFPDLNRF LTRTLQVLLPDLAAKASPAASALIRTLGKQLNVNRREILINNFKYIFSHLVCSCSKDELERALHYLKNETEIELGSLLRQDFQGLHNELL LRIGEHYQQVFNGLSILASFASSDDPYQGPRDIISPELMADYLQPKLLGILAFFNMQLLSSSVGIEDKKMALNSLMSLMKLMGPKHVSSV RVKMMTTLRTGLRFKDDFPELCCRAWDCFVRCLDHACLGSLLSHVIVALLPLIHIQPKETAAIFHYLIIENRDAVQDFLHEIYFLPDHPE LKKIKAVLQEYRKETSESTDLQTTLQLSMKAIQHENVDVRIHALTSLKETLYKNQKRLLEAMETCNHSLKKEERKRNQHSECLMCWYDRD TEFIYPSPWPEKFPAIERCCTRYKIISLDAWRVDINKNKITRIDQKALYFCGFPTLKHIRHKFFLKKSGVQVFQQSSRGENMMLEILVDA ESDELTVENVASSVLGKSVFVNWPHLEEARVVAVSDGETKFYLEEPPGTQKLYSGRTAPPSKVVHLGDKEQSNWAKEVQGISEHYLRRKG IIINETSAVVYAQLLTGRKYQINQNGEVRLEKQWSKQVVPFVYQTIVKDIRAFDSRFSNIKTLDDLFPLRSMVFMLGTPYYGCTGEVQDS GDVITEGRIRVIFSIPCEPNLDALIQNQHKYSIKYNPGYVLASRLGVSGYLVSRFTGSIFIGRGSRRNPHGDHKANVGLNLKFNKKNEEV PGYTKKVGSEWMYSSAAEQLLAEYLERAPELFSYIAKNSQEDVFYEDDIWPGENENGAEKVQEIITWLKGHPVSTLSRSSCDLQILDAAI VEKIEEEVEKCKQRKNNKKVRVTVKPHLLYRPLEQQHGVIPDRDAEFCLFDRVVNVRENFSVPVGLRGTIIGIKGANREADVLFEVLFDE EFPGGLTIRCSPGRGYRLPTSALVNLSHGSRSETGNQKLTAIVKPQPAVHQHSSSSSVSSGHLGALNHSPQSLFVPTQVPTKDDDEFCNI WQSLQGSGKMQYFQPTIQEKGAVLPQEISQVNQHHKSGFNDNSVKYQQRKHDPHRKFKEECKSPKAECWSQKMSNKQPNSGIENFLASLN ISKENEVQSSHHGEPPSEEHLSPQSFAMKGTRMLKEILKIDGSNTVDHKNEIKQIANEIPVSSNRRDEYGLPSQPKQNKKLASYMNKPHS ANEYHNVQSMDNMCWPAPSQIPPVSTPVTELSRICSLVGMPQPDFSFLRMPQTMTVCQVKLSNGLLVHGPQCHSENEAKEKAALFALQQL GSLGMNFPLPSQVFANYPSAVPPGTIPPAFPPPTANIMPSSSHLFGSMPWGPSVPVPGKPFHHTLYSGTMPMAGGIPGGVHNQFIPLQVT KKRVANKKNFENKEAQSSQATPVQTSQPDSSNIVKVSPRESSSASLKSSPIAQPASSFQVETASQGHSISHHKSTPISSSRRKSRKLAVN -------------------------------------------------------------- >8360_8360_3_ATR-XRN1_ATR_chr3_142253922_ENST00000383101_XRN1_chr3_142123918_ENST00000264951_length(transcript)=12187nt_BP=3875nt TTCCGGGAGGAGTTTTGGCCTCCACACGGCTCCGTCGGGCGCCGCGCTCTTCCGGCAGCGGTAGCTTTGGAGACGCCGGGAACCCGCGTT GGCGTGGTTGACTAGTGCCTCGCAGCCTCAGCATGGGGGAACATGGCCTGGAGCTGGCTTCCATGATCCCCGCCCTGCGGGAGCTGGGCA GTGCCACACCAGAGGAATATAATACAGTTGTACAGAAGCCAAGACAAATTCTGTGTCAATTCATTGACCGGATACTTACAGATGTAAATG TTGTTGCTGTAGAACTTGTAAAGAAAACTGACTCTCAGCCAACCTCCGTGATGTTGCTTGATTTCATCCAGCATATCATGAAATCCTCCC CACTTATGTTTGTAAATGTGAGTGGAAGCCATGAGGCCAAAGGCAGTTGTATTGAATTCAGTAATTGGATCATAACGAGACTTCTGCGGA TTGCAGCAACTCCCTCCTGTCATTTGTTACACAAGAAAATCTGTGAAGTCATCTGTTCATTATTATTTCTTTTTAAAAGCAAGAGTCCTG CTATTTTTGGGGTACTCACAAAAGAATTATTACAACTTTTTGAAGACTTGGTTTACCTCCATAGAAGAAATGTGATGGGTCATGCTGTGG AATGGCCAGTGGTCATGAGCCGATTTTTAAGTCAATTAGATGAACACATGGGATATTTACAATCAGCTCCTTTGCAGTTGATGAGTATGC AAAATTTAGAATTTATTGAAGTCACTTTATTAATGGTTCTTACTCGTATTATTGCAATTGTGTTTTTTAGAAGGCAAGAACTCTTACTTT GGCAGATAGGTTGTGTTCTGCTAGAGTATGGTAGTCCAAAAATTAAATCCCTAGCAATTAGCTTTTTAACAGAACTTTTTCAGCTTGGAG GACTACCAGCACAACCAGCTAGCACTTTTTTCAGCTCATTTTTGGAATTATTAAAACACCTTGTAGAAATGGATACTGACCAATTGAAAC TCTATGAAGAGCCATTATCAAAGCTGATAAAGACACTATTTCCCTTTGAAGCAGAAGCTTATAGAAATATTGAACCTGTCTATTTAAATA TGCTGCTGGAAAAACTCTGTGTCATGTTTGAAGACGGTGTGCTCATGCGGCTTAAGTCTGATTTGCTAAAAGCAGCTTTGTGCCATTTAC TGCAGTATTTCCTTAAATTTGTGCCAGCTGGGTATGAATCTGCTTTACAAGTCAGGAAGGTCTATGTGAGAAATATTTGTAAAGCTCTTT TGGATGTGCTTGGAATTGAGGTAGATGCAGAGTACTTGTTGGGCCCACTTTATGCAGCTTTGAAAATGGAAAGTATGGAAATCATTGAGG AGATTCAATGCCAAACTCAACAGGAAAACCTCAGCAGTAATAGTGATGGAATATCACCCAAAAGGCGTCGTCTCAGCTCGTCTCTAAACC CTTCTAAAAGAGCACCAAAACAGACTGAGGACCGTACTTTCAAGGACTGTCAACATAAATCCAAGAAGAAACCTTCTGTAGTGATAACTT GGATGTCATTGGATTTTTACACAAAAGTGCTTAAGAGCTGTAGAAGTTTGTTAGAATCTGTTCAGAAACTGGACCTGGAGGCAACCATTG ATAAGGTGGTGAAAATTTATGATGCTTTGATTTATATGCAAGTAAACAGTTCATTTGAAGATCATATCCTGGAAGATTTATGTGGTATGC TCTCACTTCCATGGATTTATTCCCATTCTGATGATGGCTGTTTAAAGTTGACCACATTTGCCGCTAATCTTCTAACATTAAGCTGTAGGA TTTCAGATAGCTATTCACCACAGGCACAATCACGATGTGTGTTTCTTCTGACTCTGTTTCCAAGAAGAATATTCCTTGAGTGGAGAACAG CAGTTTACAACTGGGCCCTGCAGAGCTCCCATGAAGTAATCCGGGCTAGTTGTGTTAGTGGATTTTTTATCTTATTGCAGCAGCAGAATT CTTGTAACAGAGTTCCCAAGATTCTTATAGATAAAGTCAAAGATGATTCTGACATTGTCAAGAAAGAATTTGCTTCTATACTTGGTCAAC TTGTCTGTACTCTTCACGGCATGTTTTATCTGACAAGTTCTTTAACAGAACCTTTCTCTGAACACGGACATGTGGACCTCTTCTGTAGGA ACTTGAAAGCCACTTCTCAACATGAATGTTCATCTTCTCAACTAAAAGCTTCTGTCTGCAAGCCATTCCTTTTCCTACTGAAAAAAAAAA TACCTAGTCCAGTAAAACTTGCTTTCATAGATAATCTACATCATCTTTGTAAGCATCTTGATTTTAGAGAAGATGAAACAGATGTAAAAG CAGTTCTTGGAACTTTATTAAATTTAATGGAAGATCCAGACAAAGATGTTAGAGTGGCTTTTAGTGGAAATATCAAGCACATATTGGAAT CCTTGGACTCTGAAGATGGATTTATAAAGGAGCTTTTTGTCTTAAGAATGAAGGAAGCATATACACATGCCCAAATATCAAGAAATAATG AGCTGAAGGATACCTTGATTCTTACAACAGGGGATATTGGAAGGGCCGCAAAAGGAGATTTGGTACCATTTGCACTCTTACACTTATTGC ATTGTTTGTTATCCAAGTCAGCATCTGTCTCTGGAGCAGCATACACAGAAATTAGAGCTCTGGTTGCAGCTAAAAGTGTTAAACTGCAAA GTTTTTTCAGCCAGTATAAGAAACCCATCTGTCAGTTTTTGGTAGAATCCCTTCACTCTAGTCAGATGACAGCACTTCCGAATACTCCAT GCCAGAATGCTGACGTGCGAAAACAAGATGTGGCTCACCAGAGAGAAATGGCTTTAAATACGTTGTCTGAAATTGCCAACGTTTTCGACT TTCCTGATCTTAATCGTTTTCTTACTAGGACATTACAAGTTCTACTACCTGATCTTGCTGCCAAAGCAAGCCCTGCAGCTTCTGCTCTCA TTCGAACTTTAGGAAAACAATTAAATGTCAATCGTAGAGAGATTTTAATAAACAACTTCAAATATATTTTTTCTCATTTGGTCTGTTCTT GTTCCAAAGATGAATTAGAACGTGCCCTTCATTATCTGAAGAATGAAACAGAAATTGAACTGGGGAGCCTGTTGAGACAAGATTTCCAAG GATTGCATAATGAATTATTGCTGCGTATTGGAGAACACTATCAACAGGTTTTTAATGGTTTGTCAATACTTGCCTCATTTGCATCCAGTG ATGATCCATATCAGGGCCCGAGAGATATCATATCACCTGAACTGATGGCTGATTATTTACAACCCAAATTGTTGGGCATTTTGGCTTTTT TTAACATGCAGTTACTGAGCTCTAGTGTTGGCATTGAAGATAAGAAAATGGCCTTGAACAGTTTGATGTCTTTGATGAAGTTAATGGGAC CCAAACATGTCAGTTCTGTGAGGGTGAAGATGATGACCACACTGAGAACTGGCCTTCGATTCAAGGATGATTTTCCTGAATTGTGTTGCA GAGCTTGGGACTGCTTTGTTCGCTGCCTGGATCATGCTTGTCTGGGCTCCCTTCTCAGTCATGTAATAGTAGCTTTGTTACCTCTTATAC ACATCCAGCCTAAAGAAACTGCAGCTATCTTCCACTACCTCATAATTGAAAACAGGGATGCTGTGCAAGATTTTCTTCATGAAATATATT TTTTACCTGATCATCCAGAATTAAAAAAGATAAAAGCCGTTCTCCAGGAATACAGAAAGGAGACCTCTGAGAGCACTGATCTTCAGACAA CTCTTCAGCTCTCTATGAAGGCCATTCAACATGAAAATGTCGATGTTCGTATTCATGCTCTTACAAGCTTGAAGGAAACCTTGTATAAAA ATCAGAAGCGATTATTGGAAGCCATGGAGACATGTAACCACTCCCTCAAAAAGGAAGAGAGGAAAAGAAACCAACATAGTGAGTGCCTAA TGTGCTGGTATGATAGAGACACAGAGTTTATCTATCCTTCTCCATGGCCAGAAAAGTTCCCTGCCATAGAACGATGTTGTACAAGGTATA AAATAATATCCTTAGATGCTTGGCGTGTAGACATAAACAAAAACAAAATAACCAGAATTGACCAGAAAGCATTATATTTCTGTGGATTTC CTACTCTGAAACACATCAGACACAAATTTTTTTTGAAGAAAAGTGGTGTTCAAGTATTCCAGCAAAGCAGTCGTGGAGAAAACATGATGT TGGAAATCTTAGTGGATGCAGAATCAGATGAACTTACCGTAGAAAATGTAGCTTCATCAGTGCTTGGAAAATCTGTCTTTGTTAATTGGC CTCACCTTGAGGAAGCTAGAGTCGTGGCTGTATCAGATGGAGAAACTAAGTTTTACTTGGAAGAACCTCCAGGAACACAGAAGCTTTATT CAGGAAGAACTGCCCCACCATCTAAAGTGGTTCATCTTGGAGATAAAGAACAATCTAACTGGGCAAAAGAAGTACAAGGAATTTCAGAAC ACTACCTGAGAAGAAAAGGAATAATAATAAATGAAACATCTGCAGTTGTGTATGCTCAGTTACTCACAGGTCGTAAATATCAAATAAATC AAAATGGTGAAGTTCGTCTAGAGAAACAGTGGTCAAAACAAGTTGTTCCTTTTGTTTATCAAACTATTGTCAAGGACATCCGAGCTTTCG ACTCCCGTTTCTCCAATATCAAAACATTGGATGATTTGTTTCCTCTGAGAAGTATGGTCTTTATGCTGGGAACTCCCTATTATGGCTGCA CTGGAGAAGTTCAGGATTCAGGTGATGTGATTACAGAAGGTAGGATTCGTGTGATTTTCAGCATTCCATGTGAACCCAATCTTGATGCTT TAATACAGAACCAGCATAAATATTCTATAAAGTACAACCCAGGATATGTGTTGGCCAGTCGCCTTGGAGTGAGTGGATACCTTGTTTCAA GGTTTACAGGAAGTATTTTTATTGGAAGAGGATCTAGGAGAAACCCTCATGGAGACCATAAAGCAAATGTGGGTTTAAATCTCAAATTCA ACAAGAAAAATGAGGAGGTACCTGGATATACTAAGAAAGTTGGAAGTGAATGGATGTATTCATCTGCAGCAGAACAACTTCTGGCAGAGT ACTTAGAGAGAGCTCCAGAACTATTTAGTTATATAGCCAAAAATAGCCAAGAGGATGTGTTCTATGAAGATGACATTTGGCCTGGAGAAA ATGAGAATGGTGCTGAAAAAGTTCAAGAAATTATTACTTGGCTAAAAGGACATCCTGTCAGTACTTTATCTCGTTCTTCTTGTGATTTAC AAATTCTGGATGCAGCTATTGTTGAGAAAATTGAGGAAGAAGTCGAAAAGTGCAAGCAAAGAAAGAATAATAAGAAGGTGCGAGTAACAG TGAAACCCCATTTGCTATACAGACCTTTAGAACAGCAACATGGAGTCATTCCTGATCGGGATGCAGAATTTTGTCTTTTTGACCGTGTTG TAAATGTGAGAGAAAACTTCTCAGTTCCAGTTGGCCTTCGAGGCACCATCATAGGAATAAAAGGAGCTAATAGAGAAGCCGATGTACTAT TTGAAGTATTATTTGATGAAGAATTTCCTGGAGGGTTAACAATAAGATGCTCACCTGGTAGAGGTTATCGACTGCCAACAAGTGCCTTGG TGAACCTTTCTCATGGGAGTCGCTCTGAAACTGGAAATCAGAAGTTGACAGCCATCGTAAAACCACAACCAGCTGTACATCAACATAGCT CAAGTTCATCAGTTTCCTCTGGGCATTTGGGAGCCCTCAACCATTCCCCTCAATCACTTTTTGTTCCTACTCAAGTACCTACTAAAGATG ATGATGAATTCTGCAACATTTGGCAGTCCTTACAGGGATCTGGAAAGATGCAATACTTTCAGCCAACTATACAAGAGAAGGGTGCAGTTC TACCTCAAGAAATAAGCCAAGTAAATCAACATCATAAATCTGGCTTTAATGACAACAGTGTTAAATATCAGCAAAGAAAACATGACCCTC ACAGAAAATTTAAAGAAGAGTGTAAGAGTCCTAAAGCTGAGTGTTGGTCCCAAAAAATGTCCAATAAGCAGCCTAACTCTGGAATTGAGA ACTTTTTAGCATCTTTGAATATCTCCAAAGAAAATGAAGTACAGTCATCTCATCATGGGGAGCCTCCAAGTGAAGAGCATTTGTCACCAC AGTCATTTGCCATGGGAACACGGATGCTTAAAGAAATTCTAAAAATTGATGGCTCTAACACTGTGGACCATAAGAATGAAATCAAACAGA TTGCTAATGAAATCCCTGTTTCCTCTAACAGAAGAGATGAATATGGATTACCCTCTCAGCCTAAACAAAATAAGAAATTAGCATCTTATA TGAACAAGCCTCACAGTGCTAATGAGTACCATAATGTTCAGTCTATGGACAATATGTGTTGGCCTGCCCCCAGCCAGATCCCTCCTGTAT CCACACCAGTAACTGAACTTTCTCGAATTTGTTCCCTTGTTGGAATGCCACAACCTGATTTCTCCTTTCTTAGGATGCCACAGACAATGA CCGTTTGCCAAGTAAAATTATCTAATGGCTTACTGGTACATGGGCCACAGTGCCACTCTGAAAATGAAGCCAAAGAGAAAGCTGCACTTT TTGCTTTACAACAGTTGGGCTCCTTAGGCATGAATTTCCCTTTGCCTTCACAAGTATTTGCAAATTATCCTTCAGCTGTACCACCTGGAA CCATTCCTCCAGCCTTTCCCCCACCTACTGGCTGGGATCACTATGGAAGCAACTATGCATTGGGGGCAGCTAATATAATGCCTTCGTCGT CTCATCTCTTTGGCTCAATGCCATGGGGACCATCGGTGCCAGTTCCTGGGAAGCCCTTCCATCATACTTTATATTCTGGGACCATGCCCA TGGCTGGGGGAATACCAGGGGGTGTGCACAATCAGTTTATACCTCTGCAGGTTACTAAAAAAAGGGTTGCAAACAAAAAGAACTTTGAGA ATAAGGAAGCCCAGAGTTCTCAAGCCACTCCAGTTCAGACTAGCCAGCCAGATTCTTCCAACATTGTCAAAGTAAGTCCACGGGAGAGCT CATCAGCTTCTTTGAAGTCCTCTCCGATTGCTCAACCTGCATCTTCTTTTCAAGTTGAAACTGCCTCTCAAGGCCATAGTATATCTCACC ATAAGTCAACACCAATCTCTTCTTCAAGAAGAAAATCAAGAAAACTGGCTGTTAATTTTGGTGTTTCTAAACCTTCTGAGTAAATTTGGC TCTTAGAATTAAGTTAATTTCTTCTCTTTCCATCTACCTTTTTATAAATACATATCTATGTCTCATAAAAATTAGAATGTACTATTTTAA AATAATATGTGTAAATTGAAATTTTTTTCATTTTTAAGTTATCAGGCACTTTTCATGCTGTTTAAAAGACTGTGTATCAAATTGTGCACT TTAAGTATGTGCAGTTTGTTGTATGTCAATTATACCTCAATAAATCTGTAATAAAAAACTAAATTAAACCTTGCATTAAAATAATATCAC AGTATCAGTGGACTAAACATTAAAATGTACCACTCTAATCATTGGCCTCATGATTGAAGCATCCTGAACTATGAATTAGACATCAGTTAG CAATAATAAGCATTTTTTACACTATCATTGAGGAATAATTACATGGAGCATGAAATTTGGGCCTCCAGTATAACTTACTGAATGTGGATT TTATTTCTCTTTTTAATGATGTAAGAAAATTGTCAGGAGAATGGCTCTTATTTATGTGTGTTTTAACTTATGCTTTGTTGCCTCTGAGGG TCTTTAGACCTGCTGTGAAAGGATCACATTTGTTGTGGTGCTGCCAGTTTTGCTTTATTCTAAATTTTGTACCAAAGCAACTTTAGAATA ATCAGAATATTTCATCTAACTGCTTAGAACTATAAATAGCATTCTAAATTTGAGTAAATACAATTTTTTAGGTTACTCAAGAACCAGCAT TAGTAATTTCTAGTAAAATTGTTTCAAAATCTACAGGGTACAATGATTACAAATTAATCTTCTAACAAAATAAAATATGAAATATTAGTC ATGTTAATTAATAAACTGTATTATTTTGTATAGCTTTTTATTTGCTTACCTGACATTTTATGAGAGCTTCATAGTTGGTCGGTATGTAGT GCTTCTTGGGACTGAAGAAATTCTAATTGTTGTTTAAGTTCCAAGGTGTGCTACAATATAGGAGGCACAGTCATCAGTTTGTGACATACA TTATTTACTGCCTATTTCATTCTGATTCTATATTTTTAGCTTTATGCTGAACTGTTCAATGATGCTGGGATTCTCTCTTTGCATGTCATA TGTGAATGTGTGGTTCAAGCTGTAACTGTTGAAATTATTTTAGAATTTATGACGATTTCTCAGCAGGGCCTATGTTTATATATATATATA TATTTATTCTTTAGTTTTTGTGATATGCTTATATTTTTAAGGAAGTAAGTTATAGCATACTTTTTTAAAAGTAGGAACCACAATCTTTAT ATGGAGCAGCTTGTTATATCTGATTTTCATGTAACTCATTGGAAACTCTGCCATGACTCTTAAAGTAGTCTTACTTGTTTTTTAAAATGC TGGTATTAAACTAAATGGACTCCTTTCACTAACTGCTGATTTCAGAGTTTAAATGTTAGCAGGATATTTGTGTATTAGCAGTGCCTTCAG TATAAGAGAGAAATATTCATTATCTGTCATTTATCATAGTCGTATAAGTTTCCATGATTTTATTTTCTGTTATTTTCATAAGTTCAGATG TTTATCAGTTCCCAACATTGTTTCTTTATCTGTAGTGGGATCTTGAGTAATGAGGCTCAAGTAAATCCTCAATGTGTATAATTATTGCCT CATAAACTCTCTCTTTGTTTTTAAAGGAAACATCTATTATGGTAATACAAAGAAAAGTTAAATTGTGACAGTAATGTTATATTAACCTCT TCCTACTTTAAAGTGTGAAATGTTTCACCTCAGCTGTACAAACTCCAGCATTGAGAATTTGCCTCACTCATTACTCCTGTGTGACAGTTA TATAAATAGCATGCAGCTCACATCTGTTTTAGAGCATAGAAGAAGCGGCACCTGCCATCTTCTGAAAACTCCAAAGGGAAATTTCAGTAG ACATAGTGCACTAAACCCATAAGGATACTTGACCAATATTTGAGCACAGCAAGCTGACAGTTCTATACAGATAGGCAGTGAAAGAGTTTT ATTTTCCAGCCAGGCGCAGTGGCTCAAATCCCAGCACTTCGGGAGGCTAAGGCAGGCGGATCACTTGAGGTCCGGAGTTCCAGACAAGCC TGGCCAACATGATGAAGCCCTGTCTCTACTAAAAATACAAAAATTAGCCGGGCGTGATGGCACATGCCTTTAGTCCCAGCTACTCGGGAG GCTGAGGCATGAGAATCATTTGAACCCGCGAGGCAGAGTCTGCAGTGAGCCGAGATTGCACCACTGCACTCCAGCCTGGAGAGCAGAGCA AGACTCTGTCTCAAAAAAAAGAAAAAAGTTTTATTATCCTTACTTTTTTTTTAACATTATTATTCTAAAGGTCAAAACTGAGAAGAGATT AAGATAGGAGAGAGCTCCATAATGGCTGGATAGTGGTCAGGCATTCTCTATTCTTTTCCCCCTGTAGACCCATTCTAAATGTGGGCCTGA GGTCAATGGGAGATGTGCCCTCCCTATGGAGGATGTAAGAAGCAGAGGCCATTTCTGCCCCATGTTGAGGAAACAATCTGTTGATAGACC TGGAATTTAGAGTATATCTGAAAAGCAGTTGGACTTCAAGAAATTTAAAATTCTCTCTTTGAGATGGGGTGGACTAAGACCACCCCCAAA GTTTAAAAATATGCTCATTCAACTTGAATCTTCTGAGGACTTTTTGTGAAAATGGTGGACTGTTTAGGGCATAGGACAGATTCCCCAAAT TGCTTTATGCTTCCACATAACTAGAGCACTTCAATCTATTTAAGCCTTTGTCTCCTAACTGAAACATTATTTCTAAATATTTCTATTCAA TAAGTTTTTTCTTTTTTGAGCAACTTAAGTGAATTTTGAAGATTGCTCCTTCCAGTCTCGTTCCTTTTCACATTTTCCTGCATTACCTAA TAATTACCTCAGCGTTAGAATTTGAATGTATTAATTGATTTAAACATCATGTAGACTAAAGTCTTAAACATCTAAGACTCAGTTGTAGTT GCAGAAAAAAATTAAAGTCACCTCTACTGAACCTTGGTTTCAATTTAAGATTTTTCTTGCTTTTCAAAGGGGTAACTAATAAAGATTGAA GGGTTTTTTTCCCGATTGGTGGAGGAATGAAGAACTATTGATGCAAGTTTTTTTATTGTTTCTTTCTATGATCAGGTACCTGCTTTCATT TTAGACTGCTACTTCCAAACTAAGCTAGATTCTTGGTTTTAATGAGAGGAGGCAGAGAGAGGGAGGCAGATGGAAGAAGAAAAACAGTTA AATAAGACATACCCAGTCACTGCATTTTTGGACTATACCGTATCTTTCTAGCACAAGGAAATAGATAAACTGTAAGGTCTTTTTTACTCA CTTTTTATTTATGTGTTCTATTTGTGTTAGTCATAACTGTTTATAGTGGTTGTCTAATTTTTACTTTTATTATATGAGATAGAGCTGTGC AGATCTTCACTCAAGTTAGTTCTGTCACGCTTCTTCCCATTATTTAGAGCACAGTTTTTTAAAGCAACTGTACAATTTCTCAGCCTTATG AGCTTGCTGTATTTCTTGGTATCATGTTGCTTCCAAATTTTGTTTTTACTGTAGAAGACAATTAATTTATTGTAGAGAAGTGGCTGTGAA AGTCGTTCTCTGTCTTTAAAAATCAATTGCAGAAGTTCATTTGTCATTTTTCTAGAGATAAATTATAGTACTCAAACTGGCAGTGCTCAG TATATACATTTTGTAAGCTTTGTCAGTGAAACCATCAGTTTTGCAGGAGCTTCCTTTCCTAGTCAAGATAAAGCTTAAAATTCCAGAAAT TAATGTCGTTCGGACTGACTTTATTCATATTTCCATCAAACTTCTCCAATACAGTAAGAGATAGTGTTGAACCAGCATCAAGTCTCCAGA AACATGGCAGAGCAGACAGGCCGTTAAGTTTCACAGACATCATAGATCCTTTTCTTAAAGAAGAAAAACATGTATAAAATAGTTTTAGTA GTCCAAAATGTCAACTATCTGTAGCTGCTTTTGTGTGTGTGTCAGTGAACAAATAATAATGCCTTGCTCAATCAATGCATTCAGCCATCT CAAGTGCAATTTGTGAAGGAGACTATGGTTTCCAAAAGATACATTTTTTTACAAAGTTAAACCTGTAAAAAGTCTTTTTTTTTTTCCCTC CAGCCGTACACCAACTGCACTTGGTTGTTTCAGCAGTTGGTATACTATTAAATTGTCCAGGCCAAATAGGTTTCTGTAGCTGTTTTAGTA ATTTGAAGCCAAATTCTCATGCTGTTTCTCATTAAAAAGAATGAGAATTTGGTCCATAGTTAGCTTTAAGTTCTCTCTTCCTTTCTTTCC CTTACAGTTAAGGGTTTGGTGGGGGATGGGGAGGTTGTTTTCGTTTTTTGGATTTTTTTGTCTTTTGGCTTTAAGTATCATATTTTCTTT TGCCTGTATCCAACTGCTTCTTTGAGTATTTTCATCTAGTTTAATGTGAGTAATAGATGCTGTGCTGTCATTGAAGTGTTCAACATTTTG TTCATTTAAACAAAAGTGTAATTCATACATATATAGATACATATCTTAATTGATTTCTCAACTATTTTATAAGTAACTGGAATTTTTCAT TAGATCTTATACAGAGAAGTATTTTATTAAAAATTCAAAAGGGAAGACTTTTATGTGCTCATTTTGTAATTTTTGATTTTAAATATCTTT ACATTGTCTGCCAATTAAAGTGTTTTAAACTTGCATTGGAATGGACTCCGAATGTATTTTTGTGGTGTTACGTTATCCGTAGATTTCTAG CATGAAGTTAGCCTCACGATGCTGTGCAAAGGATTTTAAAATATGAGAGTCACTGAAAGAGTTTAAACATCTGTTCATGTTAAATGCTCT >8360_8360_3_ATR-XRN1_ATR_chr3_142253922_ENST00000383101_XRN1_chr3_142123918_ENST00000264951_length(amino acids)=2386AA_BP=0 MGEHGLELASMIPALRELGSATPEEYNTVVQKPRQILCQFIDRILTDVNVVAVELVKKTDSQPTSVMLLDFIQHIMKSSPLMFVNVSGSH EAKGSCIEFSNWIITRLLRIAATPSCHLLHKKICEVICSLLFLFKSKSPAIFGVLTKELLQLFEDLVYLHRRNVMGHAVEWPVVMSRFLS QLDEHMGYLQSAPLQLMSMQNLEFIEVTLLMVLTRIIAIVFFRRQELLLWQIGCVLLEYGSPKIKSLAISFLTELFQLGGLPAQPASTFF SSFLELLKHLVEMDTDQLKLYEEPLSKLIKTLFPFEAEAYRNIEPVYLNMLLEKLCVMFEDGVLMRLKSDLLKAALCHLLQYFLKFVPAG YESALQVRKVYVRNICKALLDVLGIEVDAEYLLGPLYAALKMESMEIIEEIQCQTQQENLSSNSDGISPKRRRLSSSLNPSKRAPKQTED RTFKDCQHKSKKKPSVVITWMSLDFYTKVLKSCRSLLESVQKLDLEATIDKVVKIYDALIYMQVNSSFEDHILEDLCGMLSLPWIYSHSD DGCLKLTTFAANLLTLSCRISDSYSPQAQSRCVFLLTLFPRRIFLEWRTAVYNWALQSSHEVIRASCVSGFFILLQQQNSCNRVPKILID KVKDDSDIVKKEFASILGQLVCTLHGMFYLTSSLTEPFSEHGHVDLFCRNLKATSQHECSSSQLKASVCKPFLFLLKKKIPSPVKLAFID NLHHLCKHLDFREDETDVKAVLGTLLNLMEDPDKDVRVAFSGNIKHILESLDSEDGFIKELFVLRMKEAYTHAQISRNNELKDTLILTTG DIGRAAKGDLVPFALLHLLHCLLSKSASVSGAAYTEIRALVAAKSVKLQSFFSQYKKPICQFLVESLHSSQMTALPNTPCQNADVRKQDV AHQREMALNTLSEIANVFDFPDLNRFLTRTLQVLLPDLAAKASPAASALIRTLGKQLNVNRREILINNFKYIFSHLVCSCSKDELERALH YLKNETEIELGSLLRQDFQGLHNELLLRIGEHYQQVFNGLSILASFASSDDPYQGPRDIISPELMADYLQPKLLGILAFFNMQLLSSSVG IEDKKMALNSLMSLMKLMGPKHVSSVRVKMMTTLRTGLRFKDDFPELCCRAWDCFVRCLDHACLGSLLSHVIVALLPLIHIQPKETAAIF HYLIIENRDAVQDFLHEIYFLPDHPELKKIKAVLQEYRKETSESTDLQTTLQLSMKAIQHENVDVRIHALTSLKETLYKNQKRLLEAMET CNHSLKKEERKRNQHSECLMCWYDRDTEFIYPSPWPEKFPAIERCCTRYKIISLDAWRVDINKNKITRIDQKALYFCGFPTLKHIRHKFF LKKSGVQVFQQSSRGENMMLEILVDAESDELTVENVASSVLGKSVFVNWPHLEEARVVAVSDGETKFYLEEPPGTQKLYSGRTAPPSKVV HLGDKEQSNWAKEVQGISEHYLRRKGIIINETSAVVYAQLLTGRKYQINQNGEVRLEKQWSKQVVPFVYQTIVKDIRAFDSRFSNIKTLD DLFPLRSMVFMLGTPYYGCTGEVQDSGDVITEGRIRVIFSIPCEPNLDALIQNQHKYSIKYNPGYVLASRLGVSGYLVSRFTGSIFIGRG SRRNPHGDHKANVGLNLKFNKKNEEVPGYTKKVGSEWMYSSAAEQLLAEYLERAPELFSYIAKNSQEDVFYEDDIWPGENENGAEKVQEI ITWLKGHPVSTLSRSSCDLQILDAAIVEKIEEEVEKCKQRKNNKKVRVTVKPHLLYRPLEQQHGVIPDRDAEFCLFDRVVNVRENFSVPV GLRGTIIGIKGANREADVLFEVLFDEEFPGGLTIRCSPGRGYRLPTSALVNLSHGSRSETGNQKLTAIVKPQPAVHQHSSSSSVSSGHLG ALNHSPQSLFVPTQVPTKDDDEFCNIWQSLQGSGKMQYFQPTIQEKGAVLPQEISQVNQHHKSGFNDNSVKYQQRKHDPHRKFKEECKSP KAECWSQKMSNKQPNSGIENFLASLNISKENEVQSSHHGEPPSEEHLSPQSFAMGTRMLKEILKIDGSNTVDHKNEIKQIANEIPVSSNR RDEYGLPSQPKQNKKLASYMNKPHSANEYHNVQSMDNMCWPAPSQIPPVSTPVTELSRICSLVGMPQPDFSFLRMPQTMTVCQVKLSNGL LVHGPQCHSENEAKEKAALFALQQLGSLGMNFPLPSQVFANYPSAVPPGTIPPAFPPPTGWDHYGSNYALGAANIMPSSSHLFGSMPWGP SVPVPGKPFHHTLYSGTMPMAGGIPGGVHNQFIPLQVTKKRVANKKNFENKEAQSSQATPVQTSQPDSSNIVKVSPRESSSASLKSSPIA -------------------------------------------------------------- >8360_8360_4_ATR-XRN1_ATR_chr3_142253922_ENST00000383101_XRN1_chr3_142123918_ENST00000392981_length(transcript)=7497nt_BP=3875nt TTCCGGGAGGAGTTTTGGCCTCCACACGGCTCCGTCGGGCGCCGCGCTCTTCCGGCAGCGGTAGCTTTGGAGACGCCGGGAACCCGCGTT GGCGTGGTTGACTAGTGCCTCGCAGCCTCAGCATGGGGGAACATGGCCTGGAGCTGGCTTCCATGATCCCCGCCCTGCGGGAGCTGGGCA GTGCCACACCAGAGGAATATAATACAGTTGTACAGAAGCCAAGACAAATTCTGTGTCAATTCATTGACCGGATACTTACAGATGTAAATG TTGTTGCTGTAGAACTTGTAAAGAAAACTGACTCTCAGCCAACCTCCGTGATGTTGCTTGATTTCATCCAGCATATCATGAAATCCTCCC CACTTATGTTTGTAAATGTGAGTGGAAGCCATGAGGCCAAAGGCAGTTGTATTGAATTCAGTAATTGGATCATAACGAGACTTCTGCGGA TTGCAGCAACTCCCTCCTGTCATTTGTTACACAAGAAAATCTGTGAAGTCATCTGTTCATTATTATTTCTTTTTAAAAGCAAGAGTCCTG CTATTTTTGGGGTACTCACAAAAGAATTATTACAACTTTTTGAAGACTTGGTTTACCTCCATAGAAGAAATGTGATGGGTCATGCTGTGG AATGGCCAGTGGTCATGAGCCGATTTTTAAGTCAATTAGATGAACACATGGGATATTTACAATCAGCTCCTTTGCAGTTGATGAGTATGC AAAATTTAGAATTTATTGAAGTCACTTTATTAATGGTTCTTACTCGTATTATTGCAATTGTGTTTTTTAGAAGGCAAGAACTCTTACTTT GGCAGATAGGTTGTGTTCTGCTAGAGTATGGTAGTCCAAAAATTAAATCCCTAGCAATTAGCTTTTTAACAGAACTTTTTCAGCTTGGAG GACTACCAGCACAACCAGCTAGCACTTTTTTCAGCTCATTTTTGGAATTATTAAAACACCTTGTAGAAATGGATACTGACCAATTGAAAC TCTATGAAGAGCCATTATCAAAGCTGATAAAGACACTATTTCCCTTTGAAGCAGAAGCTTATAGAAATATTGAACCTGTCTATTTAAATA TGCTGCTGGAAAAACTCTGTGTCATGTTTGAAGACGGTGTGCTCATGCGGCTTAAGTCTGATTTGCTAAAAGCAGCTTTGTGCCATTTAC TGCAGTATTTCCTTAAATTTGTGCCAGCTGGGTATGAATCTGCTTTACAAGTCAGGAAGGTCTATGTGAGAAATATTTGTAAAGCTCTTT TGGATGTGCTTGGAATTGAGGTAGATGCAGAGTACTTGTTGGGCCCACTTTATGCAGCTTTGAAAATGGAAAGTATGGAAATCATTGAGG AGATTCAATGCCAAACTCAACAGGAAAACCTCAGCAGTAATAGTGATGGAATATCACCCAAAAGGCGTCGTCTCAGCTCGTCTCTAAACC CTTCTAAAAGAGCACCAAAACAGACTGAGGACCGTACTTTCAAGGACTGTCAACATAAATCCAAGAAGAAACCTTCTGTAGTGATAACTT GGATGTCATTGGATTTTTACACAAAAGTGCTTAAGAGCTGTAGAAGTTTGTTAGAATCTGTTCAGAAACTGGACCTGGAGGCAACCATTG ATAAGGTGGTGAAAATTTATGATGCTTTGATTTATATGCAAGTAAACAGTTCATTTGAAGATCATATCCTGGAAGATTTATGTGGTATGC TCTCACTTCCATGGATTTATTCCCATTCTGATGATGGCTGTTTAAAGTTGACCACATTTGCCGCTAATCTTCTAACATTAAGCTGTAGGA TTTCAGATAGCTATTCACCACAGGCACAATCACGATGTGTGTTTCTTCTGACTCTGTTTCCAAGAAGAATATTCCTTGAGTGGAGAACAG CAGTTTACAACTGGGCCCTGCAGAGCTCCCATGAAGTAATCCGGGCTAGTTGTGTTAGTGGATTTTTTATCTTATTGCAGCAGCAGAATT CTTGTAACAGAGTTCCCAAGATTCTTATAGATAAAGTCAAAGATGATTCTGACATTGTCAAGAAAGAATTTGCTTCTATACTTGGTCAAC TTGTCTGTACTCTTCACGGCATGTTTTATCTGACAAGTTCTTTAACAGAACCTTTCTCTGAACACGGACATGTGGACCTCTTCTGTAGGA ACTTGAAAGCCACTTCTCAACATGAATGTTCATCTTCTCAACTAAAAGCTTCTGTCTGCAAGCCATTCCTTTTCCTACTGAAAAAAAAAA TACCTAGTCCAGTAAAACTTGCTTTCATAGATAATCTACATCATCTTTGTAAGCATCTTGATTTTAGAGAAGATGAAACAGATGTAAAAG CAGTTCTTGGAACTTTATTAAATTTAATGGAAGATCCAGACAAAGATGTTAGAGTGGCTTTTAGTGGAAATATCAAGCACATATTGGAAT CCTTGGACTCTGAAGATGGATTTATAAAGGAGCTTTTTGTCTTAAGAATGAAGGAAGCATATACACATGCCCAAATATCAAGAAATAATG AGCTGAAGGATACCTTGATTCTTACAACAGGGGATATTGGAAGGGCCGCAAAAGGAGATTTGGTACCATTTGCACTCTTACACTTATTGC ATTGTTTGTTATCCAAGTCAGCATCTGTCTCTGGAGCAGCATACACAGAAATTAGAGCTCTGGTTGCAGCTAAAAGTGTTAAACTGCAAA GTTTTTTCAGCCAGTATAAGAAACCCATCTGTCAGTTTTTGGTAGAATCCCTTCACTCTAGTCAGATGACAGCACTTCCGAATACTCCAT GCCAGAATGCTGACGTGCGAAAACAAGATGTGGCTCACCAGAGAGAAATGGCTTTAAATACGTTGTCTGAAATTGCCAACGTTTTCGACT TTCCTGATCTTAATCGTTTTCTTACTAGGACATTACAAGTTCTACTACCTGATCTTGCTGCCAAAGCAAGCCCTGCAGCTTCTGCTCTCA TTCGAACTTTAGGAAAACAATTAAATGTCAATCGTAGAGAGATTTTAATAAACAACTTCAAATATATTTTTTCTCATTTGGTCTGTTCTT GTTCCAAAGATGAATTAGAACGTGCCCTTCATTATCTGAAGAATGAAACAGAAATTGAACTGGGGAGCCTGTTGAGACAAGATTTCCAAG GATTGCATAATGAATTATTGCTGCGTATTGGAGAACACTATCAACAGGTTTTTAATGGTTTGTCAATACTTGCCTCATTTGCATCCAGTG ATGATCCATATCAGGGCCCGAGAGATATCATATCACCTGAACTGATGGCTGATTATTTACAACCCAAATTGTTGGGCATTTTGGCTTTTT TTAACATGCAGTTACTGAGCTCTAGTGTTGGCATTGAAGATAAGAAAATGGCCTTGAACAGTTTGATGTCTTTGATGAAGTTAATGGGAC CCAAACATGTCAGTTCTGTGAGGGTGAAGATGATGACCACACTGAGAACTGGCCTTCGATTCAAGGATGATTTTCCTGAATTGTGTTGCA GAGCTTGGGACTGCTTTGTTCGCTGCCTGGATCATGCTTGTCTGGGCTCCCTTCTCAGTCATGTAATAGTAGCTTTGTTACCTCTTATAC ACATCCAGCCTAAAGAAACTGCAGCTATCTTCCACTACCTCATAATTGAAAACAGGGATGCTGTGCAAGATTTTCTTCATGAAATATATT TTTTACCTGATCATCCAGAATTAAAAAAGATAAAAGCCGTTCTCCAGGAATACAGAAAGGAGACCTCTGAGAGCACTGATCTTCAGACAA CTCTTCAGCTCTCTATGAAGGCCATTCAACATGAAAATGTCGATGTTCGTATTCATGCTCTTACAAGCTTGAAGGAAACCTTGTATAAAA ATCAGAAGCGATTATTGGAAGCCATGGAGACATGTAACCACTCCCTCAAAAAGGAAGAGAGGAAAAGAAACCAACATAGTGAGTGCCTAA TGTGCTGGTATGATAGAGACACAGAGTTTATCTATCCTTCTCCATGGCCAGAAAAGTTCCCTGCCATAGAACGATGTTGTACAAGGTATA AAATAATATCCTTAGATGCTTGGCGTGTAGACATAAACAAAAACAAAATAACCAGAATTGACCAGAAAGCATTATATTTCTGTGGATTTC CTACTCTGAAACACATCAGACACAAATTTTTTTTGAAGAAAAGTGGTGTTCAAGTATTCCAGCAAAGCAGTCGTGGAGAAAACATGATGT TGGAAATCTTAGTGGATGCAGAATCAGATGAACTTACCGTAGAAAATGTAGCTTCATCAGTGCTTGGAAAATCTGTCTTTGTTAATTGGC CTCACCTTGAGGAAGCTAGAGTCGTGGCTGTATCAGATGGAGAAACTAAGTTTTACTTGGAAGAACCTCCAGGAACACAGAAGCTTTATT CAGGAAGAACTGCCCCACCATCTAAAGTGGTTCATCTTGGAGATAAAGAACAATCTAACTGGGCAAAAGAAGTACAAGGAATTTCAGAAC ACTACCTGAGAAGAAAAGGAATAATAATAAATGAAACATCTGCAGTTGTGTATGCTCAGTTACTCACAGGTCGTAAATATCAAATAAATC AAAATGGTGAAGTTCGTCTAGAGAAACAGTGGTCAAAACAAGTTGTTCCTTTTGTTTATCAAACTATTGTCAAGGACATCCGAGCTTTCG ACTCCCGTTTCTCCAATATCAAAACATTGGATGATTTGTTTCCTCTGAGAAGTATGGTCTTTATGCTGGGAACTCCCTATTATGGCTGCA CTGGAGAAGTTCAGGATTCAGGTGATGTGATTACAGAAGGTAGGATTCGTGTGATTTTCAGCATTCCATGTGAACCCAATCTTGATGCTT TAATACAGAACCAGCATAAATATTCTATAAAGTACAACCCAGGATATGTGTTGGCCAGTCGCCTTGGAGTGAGTGGATACCTTGTTTCAA GGTTTACAGGAAGTATTTTTATTGGAAGAGGATCTAGGAGAAACCCTCATGGAGACCATAAAGCAAATGTGGGTTTAAATCTCAAATTCA ACAAGAAAAATGAGGAGGTACCTGGATATACTAAGAAAGTTGGAAGTGAATGGATGTATTCATCTGCAGCAGAACAACTTCTGGCAGAGT ACTTAGAGAGAGCTCCAGAACTATTTAGTTATATAGCCAAAAATAGCCAAGAGGATGTGTTCTATGAAGATGACATTTGGCCTGGAGAAA ATGAGAATGGTGCTGAAAAAGTTCAAGAAATTATTACTTGGCTAAAAGGACATCCTGTCAGTACTTTATCTCGTTCTTCTTGTGATTTAC AAATTCTGGATGCAGCTATTGTTGAGAAAATTGAGGAAGAAGTCGAAAAGTGCAAGCAAAGAAAGAATAATAAGAAGGTGCGAGTAACAG TGAAACCCCATTTGCTATACAGACCTTTAGAACAGCAACATGGAGTCATTCCTGATCGGGATGCAGAATTTTGTCTTTTTGACCGTGTTG TAAATGTGAGAGAAAACTTCTCAGTTCCAGTTGGCCTTCGAGGCACCATCATAGGAATAAAAGGAGCTAATAGAGAAGCCGATGTACTAT TTGAAGTATTATTTGATGAAGAATTTCCTGGAGGGTTAACAATAAGATGCTCACCTGGTAGAGGTTATCGACTGCCAACAAGTGCCTTGG TGAACCTTTCTCATGGGAGTCGCTCTGAAACTGGAAATCAGAAGTTGACAGCCATCGTAAAACCACAACCAGCTGTACATCAACATAGCT CAAGTTCATCAGTTTCCTCTGGGCATTTGGGAGCCCTCAACCATTCCCCTCAATCACTTTTTGTTCCTACTCAAGTACCTACTAAAGATG ATGATGAATTCTGCAACATTTGGCAGTCCTTACAGGGATCTGGAAAGATGCAATACTTTCAGCCAACTATACAAGAGAAGGGTGCAGTTC TACCTCAAGAAATAAGCCAAGTAAATCAACATCATAAATCTGGCTTTAATGACAACAGTGTTAAATATCAGCAAAGAAAACATGACCCTC ACAGAAAATTTAAAGAAGAGTGTAAGAGTCCTAAAGCTGAGTGTTGGTCCCAAAAAATGTCCAATAAGCAGCCTAACTCTGGAATTGAGA ACTTTTTAGCATCTTTGAATATCTCCAAAGAAAATGAAGTACAGTCATCTCATCATGGGGAGCCTCCAAGTGAAGAGCATTTGTCACCAC AGTCATTTGCCATGAAGGGAACACGGATGCTTAAAGAAATTCTAAAAATTGATGGCTCTAACACTGTGGACCATAAGAATGAAATCAAAC AGATTGCTAATGAAATCCCTGTTTCCTCTAACAGAAGAGATGAATATGGATTACCCTCTCAGCCTAAACAAAATAAGAAATTAGCATCTT ATATGAACAAGCCTCACAGTGCTAATGAGTACCATAATGTTCAGTCTATGGACAATATGTGTTGGCCTGCCCCCAGCCAGATCCCTCCTG TATCCACACCAGTAACTGAACTTTCTCGAATTTGTTCCCTTGTTGGAATGCCACAACCTGATTTCTCCTTTCTTAGGATGCCACAGACAA TGACCGTTTGCCAAGTAAAATTATCTAATGGCTTACTGGTACATGGGCCACAGTGCCACTCTGAAAATGAAGCCAAAGAGAAAGCTGCAC TTTTTGCTTTACAACAGTTGGGCTCCTTAGGCATGAATTTCCCTTTGCCTTCACAAGTATTTGCAAATTATCCTTCAGCTGTACCACCTG GAACCATTCCTCCAGCCTTTCCCCCACCTACTGCTAATATAATGCCTTCGTCGTCTCATCTCTTTGGCTCAATGCCATGGGGACCATCGG TGCCAGTTCCTGGGAAGCCCTTCCATCATACTTTATATTCTGGGACCATGCCCATGGCTGGGGGAATACCAGGGGGTGTGCACAATCAGT TTATACCTCTGCAGGTTACTAAAAAAAGGGTTGCAAACAAAAAGAACTTTGAGAATAAGGAAGCCCAGAGTTCTCAAGCCACTCCAGTTC AGACTAGCCAGCCAGATTCTTCCAACATTGTCAAAGTAAGTCCACGGGAGAGCTCATCAGCTTCTTTGAAGTCCTCTCCGATTGCTCAAC CTGCATCTTCTTTTCAAGTTGAAACTGCCTCTCAAGGCCATAGTATATCTCACCATAAGTCAACACCAATCTCTTCTTCAAGAAGAAAAT CAAGAAAACTGGCTGTTAATTTTGGTGTTTCTAAACCTTCTGAGTAAATTTGGCTCTTAGAATTAAGTTAATTTCTTCTCTTTCCATCTA CCTTTTTATAAATACATATCTATGTCTCATAAAAATTAGAATGTACTATTTTAAAATAATATGTGTAAATTGAAATTTTTTTCATTTTTA AGTTATCAGGCACTTTTCATGCTGTTTAAAAGACTGTGTATCAAATTGTGCACTTTAAGTATGTGCAGTTTGTTGTATGTCAATTATACC >8360_8360_4_ATR-XRN1_ATR_chr3_142253922_ENST00000383101_XRN1_chr3_142123918_ENST00000392981_length(amino acids)=2374AA_BP=0 MGEHGLELASMIPALRELGSATPEEYNTVVQKPRQILCQFIDRILTDVNVVAVELVKKTDSQPTSVMLLDFIQHIMKSSPLMFVNVSGSH EAKGSCIEFSNWIITRLLRIAATPSCHLLHKKICEVICSLLFLFKSKSPAIFGVLTKELLQLFEDLVYLHRRNVMGHAVEWPVVMSRFLS QLDEHMGYLQSAPLQLMSMQNLEFIEVTLLMVLTRIIAIVFFRRQELLLWQIGCVLLEYGSPKIKSLAISFLTELFQLGGLPAQPASTFF SSFLELLKHLVEMDTDQLKLYEEPLSKLIKTLFPFEAEAYRNIEPVYLNMLLEKLCVMFEDGVLMRLKSDLLKAALCHLLQYFLKFVPAG YESALQVRKVYVRNICKALLDVLGIEVDAEYLLGPLYAALKMESMEIIEEIQCQTQQENLSSNSDGISPKRRRLSSSLNPSKRAPKQTED RTFKDCQHKSKKKPSVVITWMSLDFYTKVLKSCRSLLESVQKLDLEATIDKVVKIYDALIYMQVNSSFEDHILEDLCGMLSLPWIYSHSD DGCLKLTTFAANLLTLSCRISDSYSPQAQSRCVFLLTLFPRRIFLEWRTAVYNWALQSSHEVIRASCVSGFFILLQQQNSCNRVPKILID KVKDDSDIVKKEFASILGQLVCTLHGMFYLTSSLTEPFSEHGHVDLFCRNLKATSQHECSSSQLKASVCKPFLFLLKKKIPSPVKLAFID NLHHLCKHLDFREDETDVKAVLGTLLNLMEDPDKDVRVAFSGNIKHILESLDSEDGFIKELFVLRMKEAYTHAQISRNNELKDTLILTTG DIGRAAKGDLVPFALLHLLHCLLSKSASVSGAAYTEIRALVAAKSVKLQSFFSQYKKPICQFLVESLHSSQMTALPNTPCQNADVRKQDV AHQREMALNTLSEIANVFDFPDLNRFLTRTLQVLLPDLAAKASPAASALIRTLGKQLNVNRREILINNFKYIFSHLVCSCSKDELERALH YLKNETEIELGSLLRQDFQGLHNELLLRIGEHYQQVFNGLSILASFASSDDPYQGPRDIISPELMADYLQPKLLGILAFFNMQLLSSSVG IEDKKMALNSLMSLMKLMGPKHVSSVRVKMMTTLRTGLRFKDDFPELCCRAWDCFVRCLDHACLGSLLSHVIVALLPLIHIQPKETAAIF HYLIIENRDAVQDFLHEIYFLPDHPELKKIKAVLQEYRKETSESTDLQTTLQLSMKAIQHENVDVRIHALTSLKETLYKNQKRLLEAMET CNHSLKKEERKRNQHSECLMCWYDRDTEFIYPSPWPEKFPAIERCCTRYKIISLDAWRVDINKNKITRIDQKALYFCGFPTLKHIRHKFF LKKSGVQVFQQSSRGENMMLEILVDAESDELTVENVASSVLGKSVFVNWPHLEEARVVAVSDGETKFYLEEPPGTQKLYSGRTAPPSKVV HLGDKEQSNWAKEVQGISEHYLRRKGIIINETSAVVYAQLLTGRKYQINQNGEVRLEKQWSKQVVPFVYQTIVKDIRAFDSRFSNIKTLD DLFPLRSMVFMLGTPYYGCTGEVQDSGDVITEGRIRVIFSIPCEPNLDALIQNQHKYSIKYNPGYVLASRLGVSGYLVSRFTGSIFIGRG SRRNPHGDHKANVGLNLKFNKKNEEVPGYTKKVGSEWMYSSAAEQLLAEYLERAPELFSYIAKNSQEDVFYEDDIWPGENENGAEKVQEI ITWLKGHPVSTLSRSSCDLQILDAAIVEKIEEEVEKCKQRKNNKKVRVTVKPHLLYRPLEQQHGVIPDRDAEFCLFDRVVNVRENFSVPV GLRGTIIGIKGANREADVLFEVLFDEEFPGGLTIRCSPGRGYRLPTSALVNLSHGSRSETGNQKLTAIVKPQPAVHQHSSSSSVSSGHLG ALNHSPQSLFVPTQVPTKDDDEFCNIWQSLQGSGKMQYFQPTIQEKGAVLPQEISQVNQHHKSGFNDNSVKYQQRKHDPHRKFKEECKSP KAECWSQKMSNKQPNSGIENFLASLNISKENEVQSSHHGEPPSEEHLSPQSFAMKGTRMLKEILKIDGSNTVDHKNEIKQIANEIPVSSN RRDEYGLPSQPKQNKKLASYMNKPHSANEYHNVQSMDNMCWPAPSQIPPVSTPVTELSRICSLVGMPQPDFSFLRMPQTMTVCQVKLSNG LLVHGPQCHSENEAKEKAALFALQQLGSLGMNFPLPSQVFANYPSAVPPGTIPPAFPPPTANIMPSSSHLFGSMPWGPSVPVPGKPFHHT LYSGTMPMAGGIPGGVHNQFIPLQVTKKRVANKKNFENKEAQSSQATPVQTSQPDSSNIVKVSPRESSSASLKSSPIAQPASSFQVETAS -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for ATR-XRN1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for ATR-XRN1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for ATR-XRN1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | ATR | C3281203 | CUTANEOUS TELANGIECTASIA AND CANCER SYNDROME, FAMILIAL | 2 | CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT |
| Hgene | ATR | C0004681 | Bagassosis | 1 | CTD_human |
| Hgene | ATR | C0032273 | Pneumoconiosis | 1 | CTD_human |
| Hgene | ATR | C0033578 | Prostatic Neoplasms | 1 | CTD_human |
| Hgene | ATR | C0042076 | Urologic Neoplasms | 1 | CTD_human |
| Hgene | ATR | C0265202 | Seckel syndrome | 1 | GENOMICS_ENGLAND;ORPHANET |
| Hgene | ATR | C0376358 | Malignant neoplasm of prostate | 1 | CTD_human |
| Hgene | ATR | C0751571 | Cancer of Urinary Tract | 1 | CTD_human |
| Hgene | ATR | C4551474 | Seckel syndrome 1 | 1 | CTD_human;GENOMICS_ENGLAND |
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