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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ANKHD1-TIAM2 (FusionGDB2 ID:HG54882TG26230)

Fusion Gene Summary for ANKHD1-TIAM2

check button Fusion gene summary
Fusion gene informationFusion gene name: ANKHD1-TIAM2
Fusion gene ID: hg54882tg26230
HgeneTgene
Gene symbol

ANKHD1

TIAM2

Gene ID

54882

26230

Gene nameankyrin repeat and KH domain containing 1TIAM Rac1 associated GEF 2
SynonymsMASK|MASK1|PP2500|VBARPSTEF|TIAM-2
Cytomap('ANKHD1')('TIAM2')

5q31.3

6q25.2-q25.3

Type of geneprotein-codingprotein-coding
Descriptionankyrin repeat and KH domain-containing protein 1HIV-1 Vpr-binding ankyrin repeat proteinmultiple ankyrin repeats, single KH-domain homologT-lymphoma invasion and metastasis-inducing protein 2SIF and TIAM1-like exchange factorT cell lymphoma invasion and metastasis 2
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000297183, ENST00000360839, 
ENST00000394722, ENST00000394723, 
ENST00000462121, ENST00000544120, 
Fusion gene scores* DoF score29 X 9 X 8=208818 X 17 X 10=3060
# samples 1423
** MAII scorelog2(14/2088*10)=-3.89862297962492
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(23/3060*10)=-3.73382588663564
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ANKHD1 [Title/Abstract] AND TIAM2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointANKHD1(139828890)-TIAM2(155565145), # samples:3
Anticipated loss of major functional domain due to fusion event.ANKHD1-TIAM2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ANKHD1-TIAM2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ANKHD1-TIAM2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
ANKHD1-TIAM2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across ANKHD1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across TIAM2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-A2-A0CK-01AANKHD1chr5

139828890

-TIAM2chr6

155565145

+
ChimerDB4BRCATCGA-A2-A0CK-01AANKHD1chr5

139828890

+TIAM2chr6

155565145

+


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Fusion Gene ORF analysis for ANKHD1-TIAM2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000297183ENST00000275246ANKHD1chr5

139828890

+TIAM2chr6

155565145

+
5CDS-intronENST00000297183ENST00000318981ANKHD1chr5

139828890

+TIAM2chr6

155565145

+
5CDS-intronENST00000297183ENST00000360366ANKHD1chr5

139828890

+TIAM2chr6

155565145

+
5CDS-intronENST00000297183ENST00000367174ANKHD1chr5

139828890

+TIAM2chr6

155565145

+
5CDS-intronENST00000297183ENST00000449545ANKHD1chr5

139828890

+TIAM2chr6

155565145

+
5CDS-intronENST00000297183ENST00000456144ANKHD1chr5

139828890

+TIAM2chr6

155565145

+
5CDS-intronENST00000297183ENST00000456877ANKHD1chr5

139828890

+TIAM2chr6

155565145

+
5CDS-intronENST00000297183ENST00000528391ANKHD1chr5

139828890

+TIAM2chr6

155565145

+
5CDS-intronENST00000297183ENST00000529824ANKHD1chr5

139828890

+TIAM2chr6

155565145

+
5CDS-intronENST00000360839ENST00000275246ANKHD1chr5

139828890

+TIAM2chr6

155565145

+
5CDS-intronENST00000360839ENST00000318981ANKHD1chr5

139828890

+TIAM2chr6

155565145

+
5CDS-intronENST00000360839ENST00000360366ANKHD1chr5

139828890

+TIAM2chr6

155565145

+
5CDS-intronENST00000360839ENST00000367174ANKHD1chr5

139828890

+TIAM2chr6

155565145

+
5CDS-intronENST00000360839ENST00000449545ANKHD1chr5

139828890

+TIAM2chr6

155565145

+
5CDS-intronENST00000360839ENST00000456144ANKHD1chr5

139828890

+TIAM2chr6

155565145

+
5CDS-intronENST00000360839ENST00000456877ANKHD1chr5

139828890

+TIAM2chr6

155565145

+
5CDS-intronENST00000360839ENST00000528391ANKHD1chr5

139828890

+TIAM2chr6

155565145

+
5CDS-intronENST00000360839ENST00000529824ANKHD1chr5

139828890

+TIAM2chr6

155565145

+
5CDS-intronENST00000394722ENST00000275246ANKHD1chr5

139828890

+TIAM2chr6

155565145

+
5CDS-intronENST00000394722ENST00000318981ANKHD1chr5

139828890

+TIAM2chr6

155565145

+
5CDS-intronENST00000394722ENST00000360366ANKHD1chr5

139828890

+TIAM2chr6

155565145

+
5CDS-intronENST00000394722ENST00000367174ANKHD1chr5

139828890

+TIAM2chr6

155565145

+
5CDS-intronENST00000394722ENST00000449545ANKHD1chr5

139828890

+TIAM2chr6

155565145

+
5CDS-intronENST00000394722ENST00000456144ANKHD1chr5

139828890

+TIAM2chr6

155565145

+
5CDS-intronENST00000394722ENST00000456877ANKHD1chr5

139828890

+TIAM2chr6

155565145

+
5CDS-intronENST00000394722ENST00000528391ANKHD1chr5

139828890

+TIAM2chr6

155565145

+
5CDS-intronENST00000394722ENST00000529824ANKHD1chr5

139828890

+TIAM2chr6

155565145

+
5CDS-intronENST00000394723ENST00000275246ANKHD1chr5

139828890

+TIAM2chr6

155565145

+
5CDS-intronENST00000394723ENST00000318981ANKHD1chr5

139828890

+TIAM2chr6

155565145

+
5CDS-intronENST00000394723ENST00000360366ANKHD1chr5

139828890

+TIAM2chr6

155565145

+
5CDS-intronENST00000394723ENST00000367174ANKHD1chr5

139828890

+TIAM2chr6

155565145

+
5CDS-intronENST00000394723ENST00000449545ANKHD1chr5

139828890

+TIAM2chr6

155565145

+
5CDS-intronENST00000394723ENST00000456144ANKHD1chr5

139828890

+TIAM2chr6

155565145

+
5CDS-intronENST00000394723ENST00000456877ANKHD1chr5

139828890

+TIAM2chr6

155565145

+
5CDS-intronENST00000394723ENST00000528391ANKHD1chr5

139828890

+TIAM2chr6

155565145

+
5CDS-intronENST00000394723ENST00000529824ANKHD1chr5

139828890

+TIAM2chr6

155565145

+
In-frameENST00000297183ENST00000461783ANKHD1chr5

139828890

+TIAM2chr6

155565145

+
In-frameENST00000360839ENST00000461783ANKHD1chr5

139828890

+TIAM2chr6

155565145

+
In-frameENST00000394722ENST00000461783ANKHD1chr5

139828890

+TIAM2chr6

155565145

+
In-frameENST00000394723ENST00000461783ANKHD1chr5

139828890

+TIAM2chr6

155565145

+
intron-3CDSENST00000462121ENST00000461783ANKHD1chr5

139828890

+TIAM2chr6

155565145

+
intron-3CDSENST00000544120ENST00000461783ANKHD1chr5

139828890

+TIAM2chr6

155565145

+
intron-intronENST00000462121ENST00000275246ANKHD1chr5

139828890

+TIAM2chr6

155565145

+
intron-intronENST00000462121ENST00000318981ANKHD1chr5

139828890

+TIAM2chr6

155565145

+
intron-intronENST00000462121ENST00000360366ANKHD1chr5

139828890

+TIAM2chr6

155565145

+
intron-intronENST00000462121ENST00000367174ANKHD1chr5

139828890

+TIAM2chr6

155565145

+
intron-intronENST00000462121ENST00000449545ANKHD1chr5

139828890

+TIAM2chr6

155565145

+
intron-intronENST00000462121ENST00000456144ANKHD1chr5

139828890

+TIAM2chr6

155565145

+
intron-intronENST00000462121ENST00000456877ANKHD1chr5

139828890

+TIAM2chr6

155565145

+
intron-intronENST00000462121ENST00000528391ANKHD1chr5

139828890

+TIAM2chr6

155565145

+
intron-intronENST00000462121ENST00000529824ANKHD1chr5

139828890

+TIAM2chr6

155565145

+
intron-intronENST00000544120ENST00000275246ANKHD1chr5

139828890

+TIAM2chr6

155565145

+
intron-intronENST00000544120ENST00000318981ANKHD1chr5

139828890

+TIAM2chr6

155565145

+
intron-intronENST00000544120ENST00000360366ANKHD1chr5

139828890

+TIAM2chr6

155565145

+
intron-intronENST00000544120ENST00000367174ANKHD1chr5

139828890

+TIAM2chr6

155565145

+
intron-intronENST00000544120ENST00000449545ANKHD1chr5

139828890

+TIAM2chr6

155565145

+
intron-intronENST00000544120ENST00000456144ANKHD1chr5

139828890

+TIAM2chr6

155565145

+
intron-intronENST00000544120ENST00000456877ANKHD1chr5

139828890

+TIAM2chr6

155565145

+
intron-intronENST00000544120ENST00000528391ANKHD1chr5

139828890

+TIAM2chr6

155565145

+
intron-intronENST00000544120ENST00000529824ANKHD1chr5

139828890

+TIAM2chr6

155565145

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)
BP loci
(transcript)
Predicted start
(transcript)
Predicted stop
(transcript)
Seq length
(amino acids)
ENST00000360839ANKHD1chr5139828890+ENST00000461783TIAM2chr6155565145+375613961543153999
ENST00000297183ANKHD1chr5139828890+ENST00000461783TIAM2chr6155565145+372613661243123999
ENST00000394723ANKHD1chr5139828890+ENST00000461783TIAM2chr6155565145+371613561143113999
ENST00000394722ANKHD1chr5139828890+ENST00000461783TIAM2chr6155565145+36161256473013988

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000360839ENST00000461783ANKHD1chr5139828890+TIAM2chr6155565145+0.0012825740.9987174
ENST00000297183ENST00000461783ANKHD1chr5139828890+TIAM2chr6155565145+0.0011323650.99886763
ENST00000394723ENST00000461783ANKHD1chr5139828890+TIAM2chr6155565145+0.00113220.99886787
ENST00000394722ENST00000461783ANKHD1chr5139828890+TIAM2chr6155565145+0.0008130840.99918693

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Fusion Genomic Features for ANKHD1-TIAM2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
ANKHD1chr5139828890+TIAM2chr6155565144+3.65E-091
ANKHD1chr5139828890+TIAM2chr6155565144+3.65E-091

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for ANKHD1-TIAM2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr5:139828890/chr6:155565145)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneANKHD1chr5:139828890chr6:155565145ENST00000297183+7366_944142618.0Compositional biasNote=Gly-rich
HgeneANKHD1chr5:139828890chr6:155565145ENST00000360839+7346_944142543.0Compositional biasNote=Gly-rich
HgeneANKHD1chr5:139828890chr6:155565145ENST00000394722+7116_94403617.0Compositional biasNote=Gly-rich
HgeneANKHD1chr5:139828890chr6:155565145ENST00000394723+7116_94414628.0Compositional biasNote=Gly-rich
HgeneANKHD1chr5:139828890chr6:155565145ENST00000297183+736204_2334142618.0RepeatNote=ANK 1
HgeneANKHD1chr5:139828890chr6:155565145ENST00000297183+736237_2664142618.0RepeatNote=ANK 2
HgeneANKHD1chr5:139828890chr6:155565145ENST00000297183+736271_3004142618.0RepeatNote=ANK 3
HgeneANKHD1chr5:139828890chr6:155565145ENST00000297183+736304_3334142618.0RepeatNote=ANK 4
HgeneANKHD1chr5:139828890chr6:155565145ENST00000297183+736337_3664142618.0RepeatNote=ANK 5
HgeneANKHD1chr5:139828890chr6:155565145ENST00000297183+736371_4004142618.0RepeatNote=ANK 6
HgeneANKHD1chr5:139828890chr6:155565145ENST00000360839+734204_2334142543.0RepeatNote=ANK 1
HgeneANKHD1chr5:139828890chr6:155565145ENST00000360839+734237_2664142543.0RepeatNote=ANK 2
HgeneANKHD1chr5:139828890chr6:155565145ENST00000360839+734271_3004142543.0RepeatNote=ANK 3
HgeneANKHD1chr5:139828890chr6:155565145ENST00000360839+734304_3334142543.0RepeatNote=ANK 4
HgeneANKHD1chr5:139828890chr6:155565145ENST00000360839+734337_3664142543.0RepeatNote=ANK 5
HgeneANKHD1chr5:139828890chr6:155565145ENST00000360839+734371_4004142543.0RepeatNote=ANK 6
HgeneANKHD1chr5:139828890chr6:155565145ENST00000394722+711204_233403617.0RepeatNote=ANK 1
HgeneANKHD1chr5:139828890chr6:155565145ENST00000394722+711237_266403617.0RepeatNote=ANK 2
HgeneANKHD1chr5:139828890chr6:155565145ENST00000394722+711271_300403617.0RepeatNote=ANK 3
HgeneANKHD1chr5:139828890chr6:155565145ENST00000394722+711304_333403617.0RepeatNote=ANK 4
HgeneANKHD1chr5:139828890chr6:155565145ENST00000394722+711337_366403617.0RepeatNote=ANK 5
HgeneANKHD1chr5:139828890chr6:155565145ENST00000394722+711371_400403617.0RepeatNote=ANK 6
HgeneANKHD1chr5:139828890chr6:155565145ENST00000394723+711204_233414628.0RepeatNote=ANK 1
HgeneANKHD1chr5:139828890chr6:155565145ENST00000394723+711237_266414628.0RepeatNote=ANK 2
HgeneANKHD1chr5:139828890chr6:155565145ENST00000394723+711271_300414628.0RepeatNote=ANK 3
HgeneANKHD1chr5:139828890chr6:155565145ENST00000394723+711304_333414628.0RepeatNote=ANK 4
HgeneANKHD1chr5:139828890chr6:155565145ENST00000394723+711337_366414628.0RepeatNote=ANK 5
HgeneANKHD1chr5:139828890chr6:155565145ENST00000394723+711371_400414628.0RepeatNote=ANK 6
TgeneTIAM2chr5:139828890chr6:155565145ENST00000275246113628_69541627.0Coiled coilOntology_term=ECO:0000255
TgeneTIAM2chr5:139828890chr6:155565145ENST00000456877921628_6954281014.0Coiled coilOntology_term=ECO:0000255
TgeneTIAM2chr5:139828890chr6:155565145ENST000002752461131099_129341627.0DomainDH
TgeneTIAM2chr5:139828890chr6:155565145ENST000002752461131347_147841627.0DomainPH 2
TgeneTIAM2chr5:139828890chr6:155565145ENST00000275246113506_62041627.0DomainPH 1
TgeneTIAM2chr5:139828890chr6:155565145ENST00000275246113810_88141627.0DomainRBD
TgeneTIAM2chr5:139828890chr6:155565145ENST00000275246113890_97641627.0DomainPDZ
TgeneTIAM2chr5:139828890chr6:155565145ENST0000031898114261347_147811161702.0DomainPH 2
TgeneTIAM2chr5:139828890chr6:155565145ENST0000036036613251347_147811401726.0DomainPH 2
TgeneTIAM2chr5:139828890chr6:155565145ENST0000045614414271347_147811161731.0DomainPH 2
TgeneTIAM2chr5:139828890chr6:155565145ENST000004568779211099_12934281014.0DomainDH
TgeneTIAM2chr5:139828890chr6:155565145ENST000004568779211347_14784281014.0DomainPH 2
TgeneTIAM2chr5:139828890chr6:155565145ENST00000456877921506_6204281014.0DomainPH 1
TgeneTIAM2chr5:139828890chr6:155565145ENST00000456877921810_8814281014.0DomainRBD
TgeneTIAM2chr5:139828890chr6:155565145ENST00000456877921890_9764281014.0DomainPDZ
TgeneTIAM2chr5:139828890chr6:155565145ENST0000046178317291347_147811161702.0DomainPH 2
TgeneTIAM2chr5:139828890chr6:155565145ENST0000052982412251347_147811161731.0DomainPH 2

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneANKHD1chr5:139828890chr6:155565145ENST00000297183+7361415_14854142618.0Coiled coilOntology_term=ECO:0000255
HgeneANKHD1chr5:139828890chr6:155565145ENST00000297183+736775_8524142618.0Coiled coilOntology_term=ECO:0000255
HgeneANKHD1chr5:139828890chr6:155565145ENST00000360839+7341415_14854142543.0Coiled coilOntology_term=ECO:0000255
HgeneANKHD1chr5:139828890chr6:155565145ENST00000360839+734775_8524142543.0Coiled coilOntology_term=ECO:0000255
HgeneANKHD1chr5:139828890chr6:155565145ENST00000394722+7111415_1485403617.0Coiled coilOntology_term=ECO:0000255
HgeneANKHD1chr5:139828890chr6:155565145ENST00000394722+711775_852403617.0Coiled coilOntology_term=ECO:0000255
HgeneANKHD1chr5:139828890chr6:155565145ENST00000394723+7111415_1485414628.0Coiled coilOntology_term=ECO:0000255
HgeneANKHD1chr5:139828890chr6:155565145ENST00000394723+711775_852414628.0Coiled coilOntology_term=ECO:0000255
HgeneANKHD1chr5:139828890chr6:155565145ENST00000297183+7361977_21004142618.0Compositional biasNote=Ser-rich
HgeneANKHD1chr5:139828890chr6:155565145ENST00000297183+7362291_22994142618.0Compositional biasNote=Poly-Ser
HgeneANKHD1chr5:139828890chr6:155565145ENST00000360839+7341977_21004142543.0Compositional biasNote=Ser-rich
HgeneANKHD1chr5:139828890chr6:155565145ENST00000360839+7342291_22994142543.0Compositional biasNote=Poly-Ser
HgeneANKHD1chr5:139828890chr6:155565145ENST00000394722+7111977_2100403617.0Compositional biasNote=Ser-rich
HgeneANKHD1chr5:139828890chr6:155565145ENST00000394722+7112291_2299403617.0Compositional biasNote=Poly-Ser
HgeneANKHD1chr5:139828890chr6:155565145ENST00000394723+7111977_2100414628.0Compositional biasNote=Ser-rich
HgeneANKHD1chr5:139828890chr6:155565145ENST00000394723+7112291_2299414628.0Compositional biasNote=Poly-Ser
HgeneANKHD1chr5:139828890chr6:155565145ENST00000297183+7361695_17594142618.0DomainKH
HgeneANKHD1chr5:139828890chr6:155565145ENST00000360839+7341695_17594142543.0DomainKH
HgeneANKHD1chr5:139828890chr6:155565145ENST00000394722+7111695_1759403617.0DomainKH
HgeneANKHD1chr5:139828890chr6:155565145ENST00000394723+7111695_1759414628.0DomainKH
HgeneANKHD1chr5:139828890chr6:155565145ENST00000297183+7361054_10834142618.0RepeatNote=ANK 16
HgeneANKHD1chr5:139828890chr6:155565145ENST00000297183+7361087_11164142618.0RepeatNote=ANK 17
HgeneANKHD1chr5:139828890chr6:155565145ENST00000297183+7361121_11504142618.0RepeatNote=ANK 18
HgeneANKHD1chr5:139828890chr6:155565145ENST00000297183+7361154_11834142618.0RepeatNote=ANK 19
HgeneANKHD1chr5:139828890chr6:155565145ENST00000297183+7361189_12184142618.0RepeatNote=ANK 20
HgeneANKHD1chr5:139828890chr6:155565145ENST00000297183+7361223_12524142618.0RepeatNote=ANK 21
HgeneANKHD1chr5:139828890chr6:155565145ENST00000297183+7361256_12854142618.0RepeatNote=ANK 22
HgeneANKHD1chr5:139828890chr6:155565145ENST00000297183+7361291_13204142618.0RepeatNote=ANK 23
HgeneANKHD1chr5:139828890chr6:155565145ENST00000297183+7361324_13534142618.0RepeatNote=ANK 24
HgeneANKHD1chr5:139828890chr6:155565145ENST00000297183+7361357_13864142618.0RepeatNote=ANK 25
HgeneANKHD1chr5:139828890chr6:155565145ENST00000297183+736404_4334142618.0RepeatNote=ANK 7
HgeneANKHD1chr5:139828890chr6:155565145ENST00000297183+736437_4664142618.0RepeatNote=ANK 8
HgeneANKHD1chr5:139828890chr6:155565145ENST00000297183+736470_4994142618.0RepeatNote=ANK 9
HgeneANKHD1chr5:139828890chr6:155565145ENST00000297183+736504_5334142618.0RepeatNote=ANK 10
HgeneANKHD1chr5:139828890chr6:155565145ENST00000297183+736534_5634142618.0RepeatNote=ANK 11
HgeneANKHD1chr5:139828890chr6:155565145ENST00000297183+736567_5964142618.0RepeatNote=ANK 12
HgeneANKHD1chr5:139828890chr6:155565145ENST00000297183+736600_6294142618.0RepeatNote=ANK 13
HgeneANKHD1chr5:139828890chr6:155565145ENST00000297183+736634_6634142618.0RepeatNote=ANK 14
HgeneANKHD1chr5:139828890chr6:155565145ENST00000297183+736667_6964142618.0RepeatNote=ANK 15
HgeneANKHD1chr5:139828890chr6:155565145ENST00000360839+7341054_10834142543.0RepeatNote=ANK 16
HgeneANKHD1chr5:139828890chr6:155565145ENST00000360839+7341087_11164142543.0RepeatNote=ANK 17
HgeneANKHD1chr5:139828890chr6:155565145ENST00000360839+7341121_11504142543.0RepeatNote=ANK 18
HgeneANKHD1chr5:139828890chr6:155565145ENST00000360839+7341154_11834142543.0RepeatNote=ANK 19
HgeneANKHD1chr5:139828890chr6:155565145ENST00000360839+7341189_12184142543.0RepeatNote=ANK 20
HgeneANKHD1chr5:139828890chr6:155565145ENST00000360839+7341223_12524142543.0RepeatNote=ANK 21
HgeneANKHD1chr5:139828890chr6:155565145ENST00000360839+7341256_12854142543.0RepeatNote=ANK 22
HgeneANKHD1chr5:139828890chr6:155565145ENST00000360839+7341291_13204142543.0RepeatNote=ANK 23
HgeneANKHD1chr5:139828890chr6:155565145ENST00000360839+7341324_13534142543.0RepeatNote=ANK 24
HgeneANKHD1chr5:139828890chr6:155565145ENST00000360839+7341357_13864142543.0RepeatNote=ANK 25
HgeneANKHD1chr5:139828890chr6:155565145ENST00000360839+734404_4334142543.0RepeatNote=ANK 7
HgeneANKHD1chr5:139828890chr6:155565145ENST00000360839+734437_4664142543.0RepeatNote=ANK 8
HgeneANKHD1chr5:139828890chr6:155565145ENST00000360839+734470_4994142543.0RepeatNote=ANK 9
HgeneANKHD1chr5:139828890chr6:155565145ENST00000360839+734504_5334142543.0RepeatNote=ANK 10
HgeneANKHD1chr5:139828890chr6:155565145ENST00000360839+734534_5634142543.0RepeatNote=ANK 11
HgeneANKHD1chr5:139828890chr6:155565145ENST00000360839+734567_5964142543.0RepeatNote=ANK 12
HgeneANKHD1chr5:139828890chr6:155565145ENST00000360839+734600_6294142543.0RepeatNote=ANK 13
HgeneANKHD1chr5:139828890chr6:155565145ENST00000360839+734634_6634142543.0RepeatNote=ANK 14
HgeneANKHD1chr5:139828890chr6:155565145ENST00000360839+734667_6964142543.0RepeatNote=ANK 15
HgeneANKHD1chr5:139828890chr6:155565145ENST00000394722+7111054_1083403617.0RepeatNote=ANK 16
HgeneANKHD1chr5:139828890chr6:155565145ENST00000394722+7111087_1116403617.0RepeatNote=ANK 17
HgeneANKHD1chr5:139828890chr6:155565145ENST00000394722+7111121_1150403617.0RepeatNote=ANK 18
HgeneANKHD1chr5:139828890chr6:155565145ENST00000394722+7111154_1183403617.0RepeatNote=ANK 19
HgeneANKHD1chr5:139828890chr6:155565145ENST00000394722+7111189_1218403617.0RepeatNote=ANK 20
HgeneANKHD1chr5:139828890chr6:155565145ENST00000394722+7111223_1252403617.0RepeatNote=ANK 21
HgeneANKHD1chr5:139828890chr6:155565145ENST00000394722+7111256_1285403617.0RepeatNote=ANK 22
HgeneANKHD1chr5:139828890chr6:155565145ENST00000394722+7111291_1320403617.0RepeatNote=ANK 23
HgeneANKHD1chr5:139828890chr6:155565145ENST00000394722+7111324_1353403617.0RepeatNote=ANK 24
HgeneANKHD1chr5:139828890chr6:155565145ENST00000394722+7111357_1386403617.0RepeatNote=ANK 25
HgeneANKHD1chr5:139828890chr6:155565145ENST00000394722+711404_433403617.0RepeatNote=ANK 7
HgeneANKHD1chr5:139828890chr6:155565145ENST00000394722+711437_466403617.0RepeatNote=ANK 8
HgeneANKHD1chr5:139828890chr6:155565145ENST00000394722+711470_499403617.0RepeatNote=ANK 9
HgeneANKHD1chr5:139828890chr6:155565145ENST00000394722+711504_533403617.0RepeatNote=ANK 10
HgeneANKHD1chr5:139828890chr6:155565145ENST00000394722+711534_563403617.0RepeatNote=ANK 11
HgeneANKHD1chr5:139828890chr6:155565145ENST00000394722+711567_596403617.0RepeatNote=ANK 12
HgeneANKHD1chr5:139828890chr6:155565145ENST00000394722+711600_629403617.0RepeatNote=ANK 13
HgeneANKHD1chr5:139828890chr6:155565145ENST00000394722+711634_663403617.0RepeatNote=ANK 14
HgeneANKHD1chr5:139828890chr6:155565145ENST00000394722+711667_696403617.0RepeatNote=ANK 15
HgeneANKHD1chr5:139828890chr6:155565145ENST00000394723+7111054_1083414628.0RepeatNote=ANK 16
HgeneANKHD1chr5:139828890chr6:155565145ENST00000394723+7111087_1116414628.0RepeatNote=ANK 17
HgeneANKHD1chr5:139828890chr6:155565145ENST00000394723+7111121_1150414628.0RepeatNote=ANK 18
HgeneANKHD1chr5:139828890chr6:155565145ENST00000394723+7111154_1183414628.0RepeatNote=ANK 19
HgeneANKHD1chr5:139828890chr6:155565145ENST00000394723+7111189_1218414628.0RepeatNote=ANK 20
HgeneANKHD1chr5:139828890chr6:155565145ENST00000394723+7111223_1252414628.0RepeatNote=ANK 21
HgeneANKHD1chr5:139828890chr6:155565145ENST00000394723+7111256_1285414628.0RepeatNote=ANK 22
HgeneANKHD1chr5:139828890chr6:155565145ENST00000394723+7111291_1320414628.0RepeatNote=ANK 23
HgeneANKHD1chr5:139828890chr6:155565145ENST00000394723+7111324_1353414628.0RepeatNote=ANK 24
HgeneANKHD1chr5:139828890chr6:155565145ENST00000394723+7111357_1386414628.0RepeatNote=ANK 25
HgeneANKHD1chr5:139828890chr6:155565145ENST00000394723+711404_433414628.0RepeatNote=ANK 7
HgeneANKHD1chr5:139828890chr6:155565145ENST00000394723+711437_466414628.0RepeatNote=ANK 8
HgeneANKHD1chr5:139828890chr6:155565145ENST00000394723+711470_499414628.0RepeatNote=ANK 9
HgeneANKHD1chr5:139828890chr6:155565145ENST00000394723+711504_533414628.0RepeatNote=ANK 10
HgeneANKHD1chr5:139828890chr6:155565145ENST00000394723+711534_563414628.0RepeatNote=ANK 11
HgeneANKHD1chr5:139828890chr6:155565145ENST00000394723+711567_596414628.0RepeatNote=ANK 12
HgeneANKHD1chr5:139828890chr6:155565145ENST00000394723+711600_629414628.0RepeatNote=ANK 13
HgeneANKHD1chr5:139828890chr6:155565145ENST00000394723+711634_663414628.0RepeatNote=ANK 14
HgeneANKHD1chr5:139828890chr6:155565145ENST00000394723+711667_696414628.0RepeatNote=ANK 15
TgeneTIAM2chr5:139828890chr6:155565145ENST000003189811426628_69511161702.0Coiled coilOntology_term=ECO:0000255
TgeneTIAM2chr5:139828890chr6:155565145ENST000003603661325628_69511401726.0Coiled coilOntology_term=ECO:0000255
TgeneTIAM2chr5:139828890chr6:155565145ENST000004561441427628_69511161731.0Coiled coilOntology_term=ECO:0000255
TgeneTIAM2chr5:139828890chr6:155565145ENST000004617831729628_69511161702.0Coiled coilOntology_term=ECO:0000255
TgeneTIAM2chr5:139828890chr6:155565145ENST000005298241225628_69511161731.0Coiled coilOntology_term=ECO:0000255
TgeneTIAM2chr5:139828890chr6:155565145ENST0000031898114261099_129311161702.0DomainDH
TgeneTIAM2chr5:139828890chr6:155565145ENST000003189811426506_62011161702.0DomainPH 1
TgeneTIAM2chr5:139828890chr6:155565145ENST000003189811426810_88111161702.0DomainRBD
TgeneTIAM2chr5:139828890chr6:155565145ENST000003189811426890_97611161702.0DomainPDZ
TgeneTIAM2chr5:139828890chr6:155565145ENST0000036036613251099_129311401726.0DomainDH
TgeneTIAM2chr5:139828890chr6:155565145ENST000003603661325506_62011401726.0DomainPH 1
TgeneTIAM2chr5:139828890chr6:155565145ENST000003603661325810_88111401726.0DomainRBD
TgeneTIAM2chr5:139828890chr6:155565145ENST000003603661325890_97611401726.0DomainPDZ
TgeneTIAM2chr5:139828890chr6:155565145ENST0000045614414271099_129311161731.0DomainDH
TgeneTIAM2chr5:139828890chr6:155565145ENST000004561441427506_62011161731.0DomainPH 1
TgeneTIAM2chr5:139828890chr6:155565145ENST000004561441427810_88111161731.0DomainRBD
TgeneTIAM2chr5:139828890chr6:155565145ENST000004561441427890_97611161731.0DomainPDZ
TgeneTIAM2chr5:139828890chr6:155565145ENST0000046178317291099_129311161702.0DomainDH
TgeneTIAM2chr5:139828890chr6:155565145ENST000004617831729506_62011161702.0DomainPH 1
TgeneTIAM2chr5:139828890chr6:155565145ENST000004617831729810_88111161702.0DomainRBD
TgeneTIAM2chr5:139828890chr6:155565145ENST000004617831729890_97611161702.0DomainPDZ
TgeneTIAM2chr5:139828890chr6:155565145ENST0000052982412251099_129311161731.0DomainDH
TgeneTIAM2chr5:139828890chr6:155565145ENST000005298241225506_62011161731.0DomainPH 1
TgeneTIAM2chr5:139828890chr6:155565145ENST000005298241225810_88111161731.0DomainRBD
TgeneTIAM2chr5:139828890chr6:155565145ENST000005298241225890_97611161731.0DomainPDZ


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Fusion Gene Sequence for ANKHD1-TIAM2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>4478_4478_1_ANKHD1-TIAM2_ANKHD1_chr5_139828890_ENST00000297183_TIAM2_chr6_155565145_ENST00000461783_length(transcript)=3726nt_BP=1366nt
AGTGGCGCTGCTGGGACGGGGGAAAGGAGACGCTTCTTCCTCTTGCTGCTCTTCTCGTTCCCGAGATCAGCGGCGGCGGTGACCGCGAGT
GGGTCGGCACCGTCTCCGGCTCCGGGTGCGAACAATGCTGACTGATAGCGGAGGCGGCGGCACCTCCTTTGAGGAGGACCTGGACTCTGT
GGCTCCGCGATCCGCCCCAGCTGGGGCCTCGGAGCCGCCTCCGCCGGGAGGGGTCGGTCTGGGGATCCGCACCGTGAGGCTCTTTGGGGA
GGCCGGGCCAGCGTCGGGAGTCGGCAGCAGCGGCGGCGGCGGCAGCGGCAGCGGTACGGGCGGAGGGGACGCGGCGCTGGATTTCAAGTT
GGCGGCTGCCGTGCTGAGGACCGGGGGTGGAGGTGGTGCCTCTGGCAGTGACGAGGACGAAGTGTCCGAGGTTGAATCATTTATTTTGGA
CCAAGAAGATCTGGATAACCCAGTGCTTAAAACAACATCAGAGATATTCTTATCAAGTACTGCAGAAGGAGCAGACTTACGCACTGTGGA
TCCAGAGACACAGGCACGACTAGAAGCATTGCTAGAAGCAGCAGGAATTGGCAAATTGTCAACTGCTGATGGTAAAGCTTTTGCAGATCC
TGAGGTACTCCGGAGACTGACATCCTCAGTTAGTTGTGCACTGGATGAAGCTGCTGCTGCACTGACACGGATGAAAGCAGAAAACAGCCA
CAATGCAGGACAAGTGGACACTCGCAGTCTAGCAGAAGCTTGTTCAGATGGGGATGTTAATGCTGTTCGTAAATTGCTAGATGAAGGCAG
AAGTGTAAATGAACATACAGAAGAAGGAGAAAGCCTGCTGTGTTTGGCTTGTTCAGCAGGGTATTATGAATTAGCACAAGTATTGCTTGC
TATGCATGCTAATGTTGAAGATCGAGGGAATAAAGGAGACATAACTCCCCTGATGGCAGCTTCCAGTGGAGGTTACTTAGATATTGTGAA
ATTATTACTTCTTCATGATGCTGATGTCAACTCCCAGTCTGCAACAGGAAACACTGCGCTAACTTATGCATGTGCTGGAGGATTTGTTGA
CATTGTTAAAGTGCTCCTTAATGAAGGTGCAAATATAGAAGATCATAATGAAAATGGACATACTCCCTTAATGGAAGCAGCCAGTGCAGG
TCATGTGGAAGTTGCAAGAGTTCTTTTAGATCATGGTGCAGGCATCAACACTCATTCTAATGAATTCAAAGAAAGTGCTCTAACACTTGC
TTGCTACAAAGGCCATTTGGATATGGTTCGCTTTCTACTTGAAGCTGGTGCAGATCAAGAGCACAAAACAGATGAGATGCACACTGCCTT
AATGGAGGCCTGCATGGATTTGAGCTGCCTCTTTGAATTATACTTGGAGCCACTTCAGAATGAGACCTTTCTTACCCAAGATGAGATGGA
GTCACTTTTTGGAAGTTTGCCAGAGATGCTTGAGTTTCAGAAGGTGTTTCTGGAGACCCTGGAGGATGGGATTTCAGCATCATCTGACTT
TAACACCCTAGAAACCCCCTCACAGTTTAGAAAATTACTGTTTTCCCTTGGAGGCTCTTTCCTTTATTACGCGGACCACTTTAAACTGTA
CAGTGGATTCTGTGCTAACCATATCAAAGTACAGAAGGTTCTGGAGCGAGCTAAAACTGACAAAGCCTTCAAGGCTTTTCTGGACGCCCG
GAACCCCACCAAGCAGCATTCCTCCACGCTGGAGTCCTACCTCATCAAGCCGGTTCAGAGAGTGCTCAAGTACCCGCTGCTGCTCAAGGA
GCTGGTGTCCCTGACGGACCAGGAGAGCGAGGAGCACTACCACCTGACGGAAGCACTAAAGGCAATGGAGAAAGTAGCGAGCCACATCAA
TGAGATGCAGAAGATCTATGAGGATTATGGGACCGTGTTTGACCAGCTAGTAGCTGAGCAGAGCGGAACAGAGAAGGAGGTAACAGAACT
TTCGATGGGAGAGCTTCTGATGCACTCTACGGTTTCCTGGTTGAATCCATTTCTGTCTCTAGGAAAAGCTAGAAAGGACCTTGAGCTCAC
AGTATTTGTTTTTAAGAGAGCCGTCATACTGGTTTATAAAGAAAACTGCAAACTGAAAAAGAAATTGCCCTCGAATTCCCGGCCTGCACA
CAACTCTACTGACTTGGACCCATTTAAATTCCGCTGGTTGATCCCCATCTCCGCGCTTCAAGTCAGACTGGGGAATCCAGCAGGGACAGA
AAATAATTCCATATGGGAACTGATCCATACGAAGTCAGAAATAGAAGGACGGCCAGAAACCATCTTTCAGTTGTGTTGCAGTGACAGTGA
AAGCAAAACCAACATTGTTAAGGTGATTCGTTCTATTCTGAGGGAGAACTTCAGGCGTCACATAAAGTGTGAATTACCACTGGAGAAAAC
GTGTAAGGATCGCCTGGTACCTCTTAAGAACCGAGTTCCTGTTTCGGCCAAATTAGCTTCATCCAGGTCTTTAAAAGTCCTGAAGAATTC
CTCCAGCAACGAGTGGACCGGTGAGACTGGCAAGGGAACCTTGCTGGACTCTGACGAGGGCAGCTTGAGCAGCGGCACCCAGAGCAGCGG
CTGCCCCACGGCTGAGGGCAGGCAGGACTCCAAGAGCACTTCTCCCGGGAAATACCCACACCCCGGCTTGGCAGATTTTGCCGACAATCT
CATCAAAGAGAGTGACATCCTGAGCGATGAAGATGATGACCACCGTCAGACTGTGAAGCAGGGCAGCCCTACTAAAGACATCGAAATTCA
GTTCCAGAGACTGAGGATTTCCGAGGACCCAGACGTTCACCCCGAGGCTGAGCAGCAGCCTGGCCCGGAGTCGGGTGAGGGTCAGAAAGG
AGGAGAGCAGCCCAAACTGGTCCGGGGGCACTTCTGCCCCATTAAACGAAAAGCCAACAGCACCAAGAGGGACAGAGGAACTTTGCTCAA
GGCGCAGATCCGTCACCAGTCCCTTGACAGTCAGTCTGAAAATGCCACCATCGACCTAAATTCTGTTCTAGAGCGAGAATTCAGTGTCCA
GAGTTTAACATCTGTTGTCAGTGAGGAGTGTTTTTATGAAACAGAGAGCCACGGAAAATCATAGTATGATTCAATCCAGATATGGGTTAA
ATTCCTCATTTTACTTTTAAACTGGTGGTAAAGTGGAAATTGCAAAAAAAAAAAAAAAAAAAAACTGTTCATTCCTGGGTTTTGTGCAGT
ATACATTTTCCCACAAAATGGTTGTAAAGATTTAAGTTATTTTAATTTATTGTGGATCAGAAACCTAGATGAAACTGGTCAGAATCTGTA
AATTACTTAGTTTATATCCACTTTGAGCAGGTATCAAATGATTTAGGATCCTTAAAATTACATTCTAATAATTAAGTTATGTGGAAAAAG
TAAGGCTGGGGAAGTCGTGATTAATAGTTTTCAAAGGGCCATTTTTTAAAATCCTCTGGGCATTTTCTTTCAGCTGTTTGTTAGTTTTTG
CTTTATTTAAAGCATATTTAAGTTATTTTAATGTGGTTTAGGGGCAAAATGTGCAGATACTTCATTTTTGTAAGATAGATTGTAATAGAT
GCTGTTTATACTAAACATGTCATAACTATCTATACAGTATATATTAAAAGAAAGCTTGTACTGTATCTTATTTGATGATATTTATTTTCT

>4478_4478_1_ANKHD1-TIAM2_ANKHD1_chr5_139828890_ENST00000297183_TIAM2_chr6_155565145_ENST00000461783_length(amino acids)=999AA_BP=414
MLTDSGGGGTSFEEDLDSVAPRSAPAGASEPPPPGGVGLGIRTVRLFGEAGPASGVGSSGGGGSGSGTGGGDAALDFKLAAAVLRTGGGG
GASGSDEDEVSEVESFILDQEDLDNPVLKTTSEIFLSSTAEGADLRTVDPETQARLEALLEAAGIGKLSTADGKAFADPEVLRRLTSSVS
CALDEAAAALTRMKAENSHNAGQVDTRSLAEACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGNK
GDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDH
GAGINTHSNEFKESALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDLSCLFELYLEPLQNETFLTQDEMESLFGSLPEMLE
FQKVFLETLEDGISASSDFNTLETPSQFRKLLFSLGGSFLYYADHFKLYSGFCANHIKVQKVLERAKTDKAFKAFLDARNPTKQHSSTLE
SYLIKPVQRVLKYPLLLKELVSLTDQESEEHYHLTEALKAMEKVASHINEMQKIYEDYGTVFDQLVAEQSGTEKEVTELSMGELLMHSTV
SWLNPFLSLGKARKDLELTVFVFKRAVILVYKENCKLKKKLPSNSRPAHNSTDLDPFKFRWLIPISALQVRLGNPAGTENNSIWELIHTK
SEIEGRPETIFQLCCSDSESKTNIVKVIRSILRENFRRHIKCELPLEKTCKDRLVPLKNRVPVSAKLASSRSLKVLKNSSSNEWTGETGK
GTLLDSDEGSLSSGTQSSGCPTAEGRQDSKSTSPGKYPHPGLADFADNLIKESDILSDEDDDHRQTVKQGSPTKDIEIQFQRLRISEDPD
VHPEAEQQPGPESGEGQKGGEQPKLVRGHFCPIKRKANSTKRDRGTLLKAQIRHQSLDSQSENATIDLNSVLEREFSVQSLTSVVSEECF

--------------------------------------------------------------
>4478_4478_2_ANKHD1-TIAM2_ANKHD1_chr5_139828890_ENST00000360839_TIAM2_chr6_155565145_ENST00000461783_length(transcript)=3756nt_BP=1396nt
GGGAGGCAGCAGGTTAGGCAGTGAGAAGTTAGTGGCGCTGCTGGGACGGGGGAAAGGAGACGCTTCTTCCTCTTGCTGCTCTTCTCGTTC
CCGAGATCAGCGGCGGCGGTGACCGCGAGTGGGTCGGCACCGTCTCCGGCTCCGGGTGCGAACAATGCTGACTGATAGCGGAGGCGGCGG
CACCTCCTTTGAGGAGGACCTGGACTCTGTGGCTCCGCGATCCGCCCCAGCTGGGGCCTCGGAGCCGCCTCCGCCGGGAGGGGTCGGTCT
GGGGATCCGCACCGTGAGGCTCTTTGGGGAGGCCGGGCCAGCGTCGGGAGTCGGCAGCAGCGGCGGCGGCGGCAGCGGCAGCGGTACGGG
CGGAGGGGACGCGGCGCTGGATTTCAAGTTGGCGGCTGCCGTGCTGAGGACCGGGGGTGGAGGTGGTGCCTCTGGCAGTGACGAGGACGA
AGTGTCCGAGGTTGAATCATTTATTTTGGACCAAGAAGATCTGGATAACCCAGTGCTTAAAACAACATCAGAGATATTCTTATCAAGTAC
TGCAGAAGGAGCAGACTTACGCACTGTGGATCCAGAGACACAGGCACGACTAGAAGCATTGCTAGAAGCAGCAGGAATTGGCAAATTGTC
AACTGCTGATGGTAAAGCTTTTGCAGATCCTGAGGTACTCCGGAGACTGACATCCTCAGTTAGTTGTGCACTGGATGAAGCTGCTGCTGC
ACTGACACGGATGAAAGCAGAAAACAGCCACAATGCAGGACAAGTGGACACTCGCAGTCTAGCAGAAGCTTGTTCAGATGGGGATGTTAA
TGCTGTTCGTAAATTGCTAGATGAAGGCAGAAGTGTAAATGAACATACAGAAGAAGGAGAAAGCCTGCTGTGTTTGGCTTGTTCAGCAGG
GTATTATGAATTAGCACAAGTATTGCTTGCTATGCATGCTAATGTTGAAGATCGAGGGAATAAAGGAGACATAACTCCCCTGATGGCAGC
TTCCAGTGGAGGTTACTTAGATATTGTGAAATTATTACTTCTTCATGATGCTGATGTCAACTCCCAGTCTGCAACAGGAAACACTGCGCT
AACTTATGCATGTGCTGGAGGATTTGTTGACATTGTTAAAGTGCTCCTTAATGAAGGTGCAAATATAGAAGATCATAATGAAAATGGACA
TACTCCCTTAATGGAAGCAGCCAGTGCAGGTCATGTGGAAGTTGCAAGAGTTCTTTTAGATCATGGTGCAGGCATCAACACTCATTCTAA
TGAATTCAAAGAAAGTGCTCTAACACTTGCTTGCTACAAAGGCCATTTGGATATGGTTCGCTTTCTACTTGAAGCTGGTGCAGATCAAGA
GCACAAAACAGATGAGATGCACACTGCCTTAATGGAGGCCTGCATGGATTTGAGCTGCCTCTTTGAATTATACTTGGAGCCACTTCAGAA
TGAGACCTTTCTTACCCAAGATGAGATGGAGTCACTTTTTGGAAGTTTGCCAGAGATGCTTGAGTTTCAGAAGGTGTTTCTGGAGACCCT
GGAGGATGGGATTTCAGCATCATCTGACTTTAACACCCTAGAAACCCCCTCACAGTTTAGAAAATTACTGTTTTCCCTTGGAGGCTCTTT
CCTTTATTACGCGGACCACTTTAAACTGTACAGTGGATTCTGTGCTAACCATATCAAAGTACAGAAGGTTCTGGAGCGAGCTAAAACTGA
CAAAGCCTTCAAGGCTTTTCTGGACGCCCGGAACCCCACCAAGCAGCATTCCTCCACGCTGGAGTCCTACCTCATCAAGCCGGTTCAGAG
AGTGCTCAAGTACCCGCTGCTGCTCAAGGAGCTGGTGTCCCTGACGGACCAGGAGAGCGAGGAGCACTACCACCTGACGGAAGCACTAAA
GGCAATGGAGAAAGTAGCGAGCCACATCAATGAGATGCAGAAGATCTATGAGGATTATGGGACCGTGTTTGACCAGCTAGTAGCTGAGCA
GAGCGGAACAGAGAAGGAGGTAACAGAACTTTCGATGGGAGAGCTTCTGATGCACTCTACGGTTTCCTGGTTGAATCCATTTCTGTCTCT
AGGAAAAGCTAGAAAGGACCTTGAGCTCACAGTATTTGTTTTTAAGAGAGCCGTCATACTGGTTTATAAAGAAAACTGCAAACTGAAAAA
GAAATTGCCCTCGAATTCCCGGCCTGCACACAACTCTACTGACTTGGACCCATTTAAATTCCGCTGGTTGATCCCCATCTCCGCGCTTCA
AGTCAGACTGGGGAATCCAGCAGGGACAGAAAATAATTCCATATGGGAACTGATCCATACGAAGTCAGAAATAGAAGGACGGCCAGAAAC
CATCTTTCAGTTGTGTTGCAGTGACAGTGAAAGCAAAACCAACATTGTTAAGGTGATTCGTTCTATTCTGAGGGAGAACTTCAGGCGTCA
CATAAAGTGTGAATTACCACTGGAGAAAACGTGTAAGGATCGCCTGGTACCTCTTAAGAACCGAGTTCCTGTTTCGGCCAAATTAGCTTC
ATCCAGGTCTTTAAAAGTCCTGAAGAATTCCTCCAGCAACGAGTGGACCGGTGAGACTGGCAAGGGAACCTTGCTGGACTCTGACGAGGG
CAGCTTGAGCAGCGGCACCCAGAGCAGCGGCTGCCCCACGGCTGAGGGCAGGCAGGACTCCAAGAGCACTTCTCCCGGGAAATACCCACA
CCCCGGCTTGGCAGATTTTGCCGACAATCTCATCAAAGAGAGTGACATCCTGAGCGATGAAGATGATGACCACCGTCAGACTGTGAAGCA
GGGCAGCCCTACTAAAGACATCGAAATTCAGTTCCAGAGACTGAGGATTTCCGAGGACCCAGACGTTCACCCCGAGGCTGAGCAGCAGCC
TGGCCCGGAGTCGGGTGAGGGTCAGAAAGGAGGAGAGCAGCCCAAACTGGTCCGGGGGCACTTCTGCCCCATTAAACGAAAAGCCAACAG
CACCAAGAGGGACAGAGGAACTTTGCTCAAGGCGCAGATCCGTCACCAGTCCCTTGACAGTCAGTCTGAAAATGCCACCATCGACCTAAA
TTCTGTTCTAGAGCGAGAATTCAGTGTCCAGAGTTTAACATCTGTTGTCAGTGAGGAGTGTTTTTATGAAACAGAGAGCCACGGAAAATC
ATAGTATGATTCAATCCAGATATGGGTTAAATTCCTCATTTTACTTTTAAACTGGTGGTAAAGTGGAAATTGCAAAAAAAAAAAAAAAAA
AAAACTGTTCATTCCTGGGTTTTGTGCAGTATACATTTTCCCACAAAATGGTTGTAAAGATTTAAGTTATTTTAATTTATTGTGGATCAG
AAACCTAGATGAAACTGGTCAGAATCTGTAAATTACTTAGTTTATATCCACTTTGAGCAGGTATCAAATGATTTAGGATCCTTAAAATTA
CATTCTAATAATTAAGTTATGTGGAAAAAGTAAGGCTGGGGAAGTCGTGATTAATAGTTTTCAAAGGGCCATTTTTTAAAATCCTCTGGG
CATTTTCTTTCAGCTGTTTGTTAGTTTTTGCTTTATTTAAAGCATATTTAAGTTATTTTAATGTGGTTTAGGGGCAAAATGTGCAGATAC
TTCATTTTTGTAAGATAGATTGTAATAGATGCTGTTTATACTAAACATGTCATAACTATCTATACAGTATATATTAAAAGAAAGCTTGTA

>4478_4478_2_ANKHD1-TIAM2_ANKHD1_chr5_139828890_ENST00000360839_TIAM2_chr6_155565145_ENST00000461783_length(amino acids)=999AA_BP=414
MLTDSGGGGTSFEEDLDSVAPRSAPAGASEPPPPGGVGLGIRTVRLFGEAGPASGVGSSGGGGSGSGTGGGDAALDFKLAAAVLRTGGGG
GASGSDEDEVSEVESFILDQEDLDNPVLKTTSEIFLSSTAEGADLRTVDPETQARLEALLEAAGIGKLSTADGKAFADPEVLRRLTSSVS
CALDEAAAALTRMKAENSHNAGQVDTRSLAEACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGNK
GDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDH
GAGINTHSNEFKESALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDLSCLFELYLEPLQNETFLTQDEMESLFGSLPEMLE
FQKVFLETLEDGISASSDFNTLETPSQFRKLLFSLGGSFLYYADHFKLYSGFCANHIKVQKVLERAKTDKAFKAFLDARNPTKQHSSTLE
SYLIKPVQRVLKYPLLLKELVSLTDQESEEHYHLTEALKAMEKVASHINEMQKIYEDYGTVFDQLVAEQSGTEKEVTELSMGELLMHSTV
SWLNPFLSLGKARKDLELTVFVFKRAVILVYKENCKLKKKLPSNSRPAHNSTDLDPFKFRWLIPISALQVRLGNPAGTENNSIWELIHTK
SEIEGRPETIFQLCCSDSESKTNIVKVIRSILRENFRRHIKCELPLEKTCKDRLVPLKNRVPVSAKLASSRSLKVLKNSSSNEWTGETGK
GTLLDSDEGSLSSGTQSSGCPTAEGRQDSKSTSPGKYPHPGLADFADNLIKESDILSDEDDDHRQTVKQGSPTKDIEIQFQRLRISEDPD
VHPEAEQQPGPESGEGQKGGEQPKLVRGHFCPIKRKANSTKRDRGTLLKAQIRHQSLDSQSENATIDLNSVLEREFSVQSLTSVVSEECF

--------------------------------------------------------------
>4478_4478_3_ANKHD1-TIAM2_ANKHD1_chr5_139828890_ENST00000394722_TIAM2_chr6_155565145_ENST00000461783_length(transcript)=3616nt_BP=1256nt
GGTGACCGCGAGTGGGTCGGCACCGTCTCCGGCTCCGGGTGCGAACAATGCTGACTGATAGCGGAGGCGGCGGCACCTCCTTTGAGGAGG
ACCTGGACTCTGTGGCTCCGCGATCCGCCCCAGCTGGGGCCTCGGAGCCGCCTCCGCCGGGAGGGGTCGGTCTGGGGATCCGCACCGTGA
GGCTCTTTGGGGAGGCCGGGCCAGCGTCGGGAGTCGGCAGCAGCGGCGGCGGCGGCAGCGGCAGCGGTACGGGCGGAGGGGACGCGGCGC
TGGATTTCAAGTTGGCGGCTGCCGTGCTGAGGACCGGGGGTGGAGGTGGTGCCTCTGGCAGTGACGAGGACGAAGTGTCCGAGGTTGAAT
CATTTATTTTGGACCAAGAAGATCTGGATAACCCAGTGCTTAAAACAACATCAGAGATATTCTTATCAAGTACTGCAGAAGGAGCAGACT
TACGCACTGTGGATCCAGAGACACAGGCACGACTAGAAGCATTGCTAGAAGCAGCAGCTTTTGCAGATCCTGAGGTACTCCGGAGACTGA
CATCCTCAGTTAGTTGTGCACTGGATGAAGCTGCTGCTGCACTGACACGGATGAAAGCAGAAAACAGCCACAATGCAGGACAAGTGGACA
CTCGCAGTCTAGCAGAAGCTTGTTCAGATGGGGATGTTAATGCTGTTCGTAAATTGCTAGATGAAGGCAGAAGTGTAAATGAACATACAG
AAGAAGGAGAAAGCCTGCTGTGTTTGGCTTGTTCAGCAGGGTATTATGAATTAGCACAAGTATTGCTTGCTATGCATGCTAATGTTGAAG
ATCGAGGGAATAAAGGAGACATAACTCCCCTGATGGCAGCTTCCAGTGGAGGTTACTTAGATATTGTGAAATTATTACTTCTTCATGATG
CTGATGTCAACTCCCAGTCTGCAACAGGAAACACTGCGCTAACTTATGCATGTGCTGGAGGATTTGTTGACATTGTTAAAGTGCTCCTTA
ATGAAGGTGCAAATATAGAAGATCATAATGAAAATGGACATACTCCCTTAATGGAAGCAGCCAGTGCAGGTCATGTGGAAGTTGCAAGAG
TTCTTTTAGATCATGGTGCAGGCATCAACACTCATTCTAATGAATTCAAAGAAAGTGCTCTAACACTTGCTTGCTACAAAGGCCATTTGG
ATATGGTTCGCTTTCTACTTGAAGCTGGTGCAGATCAAGAGCACAAAACAGATGAGATGCACACTGCCTTAATGGAGGCCTGCATGGATT
TGAGCTGCCTCTTTGAATTATACTTGGAGCCACTTCAGAATGAGACCTTTCTTACCCAAGATGAGATGGAGTCACTTTTTGGAAGTTTGC
CAGAGATGCTTGAGTTTCAGAAGGTGTTTCTGGAGACCCTGGAGGATGGGATTTCAGCATCATCTGACTTTAACACCCTAGAAACCCCCT
CACAGTTTAGAAAATTACTGTTTTCCCTTGGAGGCTCTTTCCTTTATTACGCGGACCACTTTAAACTGTACAGTGGATTCTGTGCTAACC
ATATCAAAGTACAGAAGGTTCTGGAGCGAGCTAAAACTGACAAAGCCTTCAAGGCTTTTCTGGACGCCCGGAACCCCACCAAGCAGCATT
CCTCCACGCTGGAGTCCTACCTCATCAAGCCGGTTCAGAGAGTGCTCAAGTACCCGCTGCTGCTCAAGGAGCTGGTGTCCCTGACGGACC
AGGAGAGCGAGGAGCACTACCACCTGACGGAAGCACTAAAGGCAATGGAGAAAGTAGCGAGCCACATCAATGAGATGCAGAAGATCTATG
AGGATTATGGGACCGTGTTTGACCAGCTAGTAGCTGAGCAGAGCGGAACAGAGAAGGAGGTAACAGAACTTTCGATGGGAGAGCTTCTGA
TGCACTCTACGGTTTCCTGGTTGAATCCATTTCTGTCTCTAGGAAAAGCTAGAAAGGACCTTGAGCTCACAGTATTTGTTTTTAAGAGAG
CCGTCATACTGGTTTATAAAGAAAACTGCAAACTGAAAAAGAAATTGCCCTCGAATTCCCGGCCTGCACACAACTCTACTGACTTGGACC
CATTTAAATTCCGCTGGTTGATCCCCATCTCCGCGCTTCAAGTCAGACTGGGGAATCCAGCAGGGACAGAAAATAATTCCATATGGGAAC
TGATCCATACGAAGTCAGAAATAGAAGGACGGCCAGAAACCATCTTTCAGTTGTGTTGCAGTGACAGTGAAAGCAAAACCAACATTGTTA
AGGTGATTCGTTCTATTCTGAGGGAGAACTTCAGGCGTCACATAAAGTGTGAATTACCACTGGAGAAAACGTGTAAGGATCGCCTGGTAC
CTCTTAAGAACCGAGTTCCTGTTTCGGCCAAATTAGCTTCATCCAGGTCTTTAAAAGTCCTGAAGAATTCCTCCAGCAACGAGTGGACCG
GTGAGACTGGCAAGGGAACCTTGCTGGACTCTGACGAGGGCAGCTTGAGCAGCGGCACCCAGAGCAGCGGCTGCCCCACGGCTGAGGGCA
GGCAGGACTCCAAGAGCACTTCTCCCGGGAAATACCCACACCCCGGCTTGGCAGATTTTGCCGACAATCTCATCAAAGAGAGTGACATCC
TGAGCGATGAAGATGATGACCACCGTCAGACTGTGAAGCAGGGCAGCCCTACTAAAGACATCGAAATTCAGTTCCAGAGACTGAGGATTT
CCGAGGACCCAGACGTTCACCCCGAGGCTGAGCAGCAGCCTGGCCCGGAGTCGGGTGAGGGTCAGAAAGGAGGAGAGCAGCCCAAACTGG
TCCGGGGGCACTTCTGCCCCATTAAACGAAAAGCCAACAGCACCAAGAGGGACAGAGGAACTTTGCTCAAGGCGCAGATCCGTCACCAGT
CCCTTGACAGTCAGTCTGAAAATGCCACCATCGACCTAAATTCTGTTCTAGAGCGAGAATTCAGTGTCCAGAGTTTAACATCTGTTGTCA
GTGAGGAGTGTTTTTATGAAACAGAGAGCCACGGAAAATCATAGTATGATTCAATCCAGATATGGGTTAAATTCCTCATTTTACTTTTAA
ACTGGTGGTAAAGTGGAAATTGCAAAAAAAAAAAAAAAAAAAAACTGTTCATTCCTGGGTTTTGTGCAGTATACATTTTCCCACAAAATG
GTTGTAAAGATTTAAGTTATTTTAATTTATTGTGGATCAGAAACCTAGATGAAACTGGTCAGAATCTGTAAATTACTTAGTTTATATCCA
CTTTGAGCAGGTATCAAATGATTTAGGATCCTTAAAATTACATTCTAATAATTAAGTTATGTGGAAAAAGTAAGGCTGGGGAAGTCGTGA
TTAATAGTTTTCAAAGGGCCATTTTTTAAAATCCTCTGGGCATTTTCTTTCAGCTGTTTGTTAGTTTTTGCTTTATTTAAAGCATATTTA
AGTTATTTTAATGTGGTTTAGGGGCAAAATGTGCAGATACTTCATTTTTGTAAGATAGATTGTAATAGATGCTGTTTATACTAAACATGT
CATAACTATCTATACAGTATATATTAAAAGAAAGCTTGTACTGTATCTTATTTGATGATATTTATTTTCTCTGCCAAGCTGTATAGTAAA

>4478_4478_3_ANKHD1-TIAM2_ANKHD1_chr5_139828890_ENST00000394722_TIAM2_chr6_155565145_ENST00000461783_length(amino acids)=988AA_BP=403
MLTDSGGGGTSFEEDLDSVAPRSAPAGASEPPPPGGVGLGIRTVRLFGEAGPASGVGSSGGGGSGSGTGGGDAALDFKLAAAVLRTGGGG
GASGSDEDEVSEVESFILDQEDLDNPVLKTTSEIFLSSTAEGADLRTVDPETQARLEALLEAAAFADPEVLRRLTSSVSCALDEAAAALT
RMKAENSHNAGQVDTRSLAEACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGNKGDITPLMAASS
GGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEF
KESALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDLSCLFELYLEPLQNETFLTQDEMESLFGSLPEMLEFQKVFLETLED
GISASSDFNTLETPSQFRKLLFSLGGSFLYYADHFKLYSGFCANHIKVQKVLERAKTDKAFKAFLDARNPTKQHSSTLESYLIKPVQRVL
KYPLLLKELVSLTDQESEEHYHLTEALKAMEKVASHINEMQKIYEDYGTVFDQLVAEQSGTEKEVTELSMGELLMHSTVSWLNPFLSLGK
ARKDLELTVFVFKRAVILVYKENCKLKKKLPSNSRPAHNSTDLDPFKFRWLIPISALQVRLGNPAGTENNSIWELIHTKSEIEGRPETIF
QLCCSDSESKTNIVKVIRSILRENFRRHIKCELPLEKTCKDRLVPLKNRVPVSAKLASSRSLKVLKNSSSNEWTGETGKGTLLDSDEGSL
SSGTQSSGCPTAEGRQDSKSTSPGKYPHPGLADFADNLIKESDILSDEDDDHRQTVKQGSPTKDIEIQFQRLRISEDPDVHPEAEQQPGP

--------------------------------------------------------------
>4478_4478_4_ANKHD1-TIAM2_ANKHD1_chr5_139828890_ENST00000394723_TIAM2_chr6_155565145_ENST00000461783_length(transcript)=3716nt_BP=1356nt
CTGGGACGGGGGAAAGGAGACGCTTCTTCCTCTTGCTGCTCTTCTCGTTCCCGAGATCAGCGGCGGCGGTGACCGCGAGTGGGTCGGCAC
CGTCTCCGGCTCCGGGTGCGAACAATGCTGACTGATAGCGGAGGCGGCGGCACCTCCTTTGAGGAGGACCTGGACTCTGTGGCTCCGCGA
TCCGCCCCAGCTGGGGCCTCGGAGCCGCCTCCGCCGGGAGGGGTCGGTCTGGGGATCCGCACCGTGAGGCTCTTTGGGGAGGCCGGGCCA
GCGTCGGGAGTCGGCAGCAGCGGCGGCGGCGGCAGCGGCAGCGGTACGGGCGGAGGGGACGCGGCGCTGGATTTCAAGTTGGCGGCTGCC
GTGCTGAGGACCGGGGGTGGAGGTGGTGCCTCTGGCAGTGACGAGGACGAAGTGTCCGAGGTTGAATCATTTATTTTGGACCAAGAAGAT
CTGGATAACCCAGTGCTTAAAACAACATCAGAGATATTCTTATCAAGTACTGCAGAAGGAGCAGACTTACGCACTGTGGATCCAGAGACA
CAGGCACGACTAGAAGCATTGCTAGAAGCAGCAGGAATTGGCAAATTGTCAACTGCTGATGGTAAAGCTTTTGCAGATCCTGAGGTACTC
CGGAGACTGACATCCTCAGTTAGTTGTGCACTGGATGAAGCTGCTGCTGCACTGACACGGATGAAAGCAGAAAACAGCCACAATGCAGGA
CAAGTGGACACTCGCAGTCTAGCAGAAGCTTGTTCAGATGGGGATGTTAATGCTGTTCGTAAATTGCTAGATGAAGGCAGAAGTGTAAAT
GAACATACAGAAGAAGGAGAAAGCCTGCTGTGTTTGGCTTGTTCAGCAGGGTATTATGAATTAGCACAAGTATTGCTTGCTATGCATGCT
AATGTTGAAGATCGAGGGAATAAAGGAGACATAACTCCCCTGATGGCAGCTTCCAGTGGAGGTTACTTAGATATTGTGAAATTATTACTT
CTTCATGATGCTGATGTCAACTCCCAGTCTGCAACAGGAAACACTGCGCTAACTTATGCATGTGCTGGAGGATTTGTTGACATTGTTAAA
GTGCTCCTTAATGAAGGTGCAAATATAGAAGATCATAATGAAAATGGACATACTCCCTTAATGGAAGCAGCCAGTGCAGGTCATGTGGAA
GTTGCAAGAGTTCTTTTAGATCATGGTGCAGGCATCAACACTCATTCTAATGAATTCAAAGAAAGTGCTCTAACACTTGCTTGCTACAAA
GGCCATTTGGATATGGTTCGCTTTCTACTTGAAGCTGGTGCAGATCAAGAGCACAAAACAGATGAGATGCACACTGCCTTAATGGAGGCC
TGCATGGATTTGAGCTGCCTCTTTGAATTATACTTGGAGCCACTTCAGAATGAGACCTTTCTTACCCAAGATGAGATGGAGTCACTTTTT
GGAAGTTTGCCAGAGATGCTTGAGTTTCAGAAGGTGTTTCTGGAGACCCTGGAGGATGGGATTTCAGCATCATCTGACTTTAACACCCTA
GAAACCCCCTCACAGTTTAGAAAATTACTGTTTTCCCTTGGAGGCTCTTTCCTTTATTACGCGGACCACTTTAAACTGTACAGTGGATTC
TGTGCTAACCATATCAAAGTACAGAAGGTTCTGGAGCGAGCTAAAACTGACAAAGCCTTCAAGGCTTTTCTGGACGCCCGGAACCCCACC
AAGCAGCATTCCTCCACGCTGGAGTCCTACCTCATCAAGCCGGTTCAGAGAGTGCTCAAGTACCCGCTGCTGCTCAAGGAGCTGGTGTCC
CTGACGGACCAGGAGAGCGAGGAGCACTACCACCTGACGGAAGCACTAAAGGCAATGGAGAAAGTAGCGAGCCACATCAATGAGATGCAG
AAGATCTATGAGGATTATGGGACCGTGTTTGACCAGCTAGTAGCTGAGCAGAGCGGAACAGAGAAGGAGGTAACAGAACTTTCGATGGGA
GAGCTTCTGATGCACTCTACGGTTTCCTGGTTGAATCCATTTCTGTCTCTAGGAAAAGCTAGAAAGGACCTTGAGCTCACAGTATTTGTT
TTTAAGAGAGCCGTCATACTGGTTTATAAAGAAAACTGCAAACTGAAAAAGAAATTGCCCTCGAATTCCCGGCCTGCACACAACTCTACT
GACTTGGACCCATTTAAATTCCGCTGGTTGATCCCCATCTCCGCGCTTCAAGTCAGACTGGGGAATCCAGCAGGGACAGAAAATAATTCC
ATATGGGAACTGATCCATACGAAGTCAGAAATAGAAGGACGGCCAGAAACCATCTTTCAGTTGTGTTGCAGTGACAGTGAAAGCAAAACC
AACATTGTTAAGGTGATTCGTTCTATTCTGAGGGAGAACTTCAGGCGTCACATAAAGTGTGAATTACCACTGGAGAAAACGTGTAAGGAT
CGCCTGGTACCTCTTAAGAACCGAGTTCCTGTTTCGGCCAAATTAGCTTCATCCAGGTCTTTAAAAGTCCTGAAGAATTCCTCCAGCAAC
GAGTGGACCGGTGAGACTGGCAAGGGAACCTTGCTGGACTCTGACGAGGGCAGCTTGAGCAGCGGCACCCAGAGCAGCGGCTGCCCCACG
GCTGAGGGCAGGCAGGACTCCAAGAGCACTTCTCCCGGGAAATACCCACACCCCGGCTTGGCAGATTTTGCCGACAATCTCATCAAAGAG
AGTGACATCCTGAGCGATGAAGATGATGACCACCGTCAGACTGTGAAGCAGGGCAGCCCTACTAAAGACATCGAAATTCAGTTCCAGAGA
CTGAGGATTTCCGAGGACCCAGACGTTCACCCCGAGGCTGAGCAGCAGCCTGGCCCGGAGTCGGGTGAGGGTCAGAAAGGAGGAGAGCAG
CCCAAACTGGTCCGGGGGCACTTCTGCCCCATTAAACGAAAAGCCAACAGCACCAAGAGGGACAGAGGAACTTTGCTCAAGGCGCAGATC
CGTCACCAGTCCCTTGACAGTCAGTCTGAAAATGCCACCATCGACCTAAATTCTGTTCTAGAGCGAGAATTCAGTGTCCAGAGTTTAACA
TCTGTTGTCAGTGAGGAGTGTTTTTATGAAACAGAGAGCCACGGAAAATCATAGTATGATTCAATCCAGATATGGGTTAAATTCCTCATT
TTACTTTTAAACTGGTGGTAAAGTGGAAATTGCAAAAAAAAAAAAAAAAAAAAACTGTTCATTCCTGGGTTTTGTGCAGTATACATTTTC
CCACAAAATGGTTGTAAAGATTTAAGTTATTTTAATTTATTGTGGATCAGAAACCTAGATGAAACTGGTCAGAATCTGTAAATTACTTAG
TTTATATCCACTTTGAGCAGGTATCAAATGATTTAGGATCCTTAAAATTACATTCTAATAATTAAGTTATGTGGAAAAAGTAAGGCTGGG
GAAGTCGTGATTAATAGTTTTCAAAGGGCCATTTTTTAAAATCCTCTGGGCATTTTCTTTCAGCTGTTTGTTAGTTTTTGCTTTATTTAA
AGCATATTTAAGTTATTTTAATGTGGTTTAGGGGCAAAATGTGCAGATACTTCATTTTTGTAAGATAGATTGTAATAGATGCTGTTTATA
CTAAACATGTCATAACTATCTATACAGTATATATTAAAAGAAAGCTTGTACTGTATCTTATTTGATGATATTTATTTTCTCTGCCAAGCT

>4478_4478_4_ANKHD1-TIAM2_ANKHD1_chr5_139828890_ENST00000394723_TIAM2_chr6_155565145_ENST00000461783_length(amino acids)=999AA_BP=414
MLTDSGGGGTSFEEDLDSVAPRSAPAGASEPPPPGGVGLGIRTVRLFGEAGPASGVGSSGGGGSGSGTGGGDAALDFKLAAAVLRTGGGG
GASGSDEDEVSEVESFILDQEDLDNPVLKTTSEIFLSSTAEGADLRTVDPETQARLEALLEAAGIGKLSTADGKAFADPEVLRRLTSSVS
CALDEAAAALTRMKAENSHNAGQVDTRSLAEACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGNK
GDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDH
GAGINTHSNEFKESALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDLSCLFELYLEPLQNETFLTQDEMESLFGSLPEMLE
FQKVFLETLEDGISASSDFNTLETPSQFRKLLFSLGGSFLYYADHFKLYSGFCANHIKVQKVLERAKTDKAFKAFLDARNPTKQHSSTLE
SYLIKPVQRVLKYPLLLKELVSLTDQESEEHYHLTEALKAMEKVASHINEMQKIYEDYGTVFDQLVAEQSGTEKEVTELSMGELLMHSTV
SWLNPFLSLGKARKDLELTVFVFKRAVILVYKENCKLKKKLPSNSRPAHNSTDLDPFKFRWLIPISALQVRLGNPAGTENNSIWELIHTK
SEIEGRPETIFQLCCSDSESKTNIVKVIRSILRENFRRHIKCELPLEKTCKDRLVPLKNRVPVSAKLASSRSLKVLKNSSSNEWTGETGK
GTLLDSDEGSLSSGTQSSGCPTAEGRQDSKSTSPGKYPHPGLADFADNLIKESDILSDEDDDHRQTVKQGSPTKDIEIQFQRLRISEDPD
VHPEAEQQPGPESGEGQKGGEQPKLVRGHFCPIKRKANSTKRDRGTLLKAQIRHQSLDSQSENATIDLNSVLEREFSVQSLTSVVSEECF

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ANKHD1-TIAM2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ANKHD1-TIAM2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ANKHD1-TIAM2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneC0013146Drug abuse1CTD_human
TgeneC0013170Drug habituation1CTD_human
TgeneC0013222Drug Use Disorders1CTD_human
TgeneC0029231Organic Mental Disorders, Substance-Induced1CTD_human
TgeneC0038580Substance Dependence1CTD_human
TgeneC0038586Substance Use Disorders1CTD_human
TgeneC0236969Substance-Related Disorders1CTD_human
TgeneC0740858Substance abuse problem1CTD_human
TgeneC1510472Drug Dependence1CTD_human
TgeneC4316881Prescription Drug Abuse1CTD_human