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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:CASZ1-SLC9A1 (FusionGDB2 ID:HG54897TG6548)

Fusion Gene Summary for CASZ1-SLC9A1

check button Fusion gene summary
Fusion gene informationFusion gene name: CASZ1-SLC9A1
Fusion gene ID: hg54897tg6548
HgeneTgene
Gene symbol

CASZ1

SLC9A1

Gene ID

54897

6548

Gene namecastor zinc finger 1solute carrier family 9 member A1
SynonymsCAS11|CST|SRG|ZNF693|dJ734G22.1APNH|LIKNS|NHE-1|NHE1|PPP1R143
Cytomap('CASZ1')('SLC9A1')

1p36.22

1p36.11

Type of geneprotein-codingprotein-coding
Descriptionzinc finger protein castor homolog 1castor homolog 1, zinc fingercastor-related proteinsurvival-relatedzinc finger protein 693sodium/hydrogen exchanger 1Na(+)/H(+) exchanger 1Na-Li countertransporterprotein phosphatase 1, regulatory subunit 143solute carrier family 9 (sodium/hydrogen exchanger), isoform 1 (antiporter, Na+/H+, amiloride sensitive)solute carrier family 9 (sod
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000344008, ENST00000377022, 
ENST00000478728, 
Fusion gene scores* DoF score23 X 19 X 12=52449 X 7 X 7=441
# samples 3011
** MAII scorelog2(30/5244*10)=-4.12763327972587
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(11/441*10)=-2.00327513203286
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CASZ1 [Title/Abstract] AND SLC9A1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCASZ1(10753931)-SLC9A1(27440777), # samples:2
Anticipated loss of major functional domain due to fusion event.CASZ1-SLC9A1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
CASZ1-SLC9A1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
CASZ1-SLC9A1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
CASZ1-SLC9A1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
CASZ1-SLC9A1 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
CASZ1-SLC9A1 seems lost the major protein functional domain in Hgene partner, which is a transcription factor due to the frame-shifted ORF.
CASZ1-SLC9A1 seems lost the major protein functional domain in Tgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
CASZ1-SLC9A1 seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneCASZ1

GO:0045893

positive regulation of transcription, DNA-templated

27693370

TgeneSLC9A1

GO:0006883

cellular sodium ion homeostasis

24840010

TgeneSLC9A1

GO:0006885

regulation of pH

8901634

TgeneSLC9A1

GO:0010447

response to acidic pH

8901634

TgeneSLC9A1

GO:0045944

positive regulation of transcription by RNA polymerase II

22688515

TgeneSLC9A1

GO:0051453

regulation of intracellular pH

15035633|24840010

TgeneSLC9A1

GO:0070886

positive regulation of calcineurin-NFAT signaling cascade

22688515

TgeneSLC9A1

GO:0071468

cellular response to acidic pH

24840010

TgeneSLC9A1

GO:0098719

sodium ion import across plasma membrane

24840010

TgeneSLC9A1

GO:1902600

proton transmembrane transport

24840010


check buttonFusion gene breakpoints across CASZ1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across SLC9A1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4PAADTCGA-3A-A9J0-01ACASZ1chr1

10753931

-SLC9A1chr1

27436268

-
ChimerDB4PAADTCGA-3A-A9J0-01ACASZ1chr1

10753931

-SLC9A1chr1

27440777

-
ChimerDB4PAADTCGA-3A-A9J0CASZ1chr1

10753930

-SLC9A1chr1

27440777

-
ChimerDB4PAADTCGA-3A-A9J0CASZ1chr1

10753931

-SLC9A1chr1

27440777

-


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Fusion Gene ORF analysis for CASZ1-SLC9A1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000344008ENST00000374086CASZ1chr1

10753931

-SLC9A1chr1

27436268

-
5CDS-5UTRENST00000344008ENST00000545949CASZ1chr1

10753931

-SLC9A1chr1

27436268

-
5CDS-5UTRENST00000377022ENST00000374086CASZ1chr1

10753931

-SLC9A1chr1

27436268

-
5CDS-5UTRENST00000377022ENST00000545949CASZ1chr1

10753931

-SLC9A1chr1

27436268

-
5CDS-intronENST00000344008ENST00000374086CASZ1chr1

10753930

-SLC9A1chr1

27440777

-
5CDS-intronENST00000344008ENST00000374086CASZ1chr1

10753931

-SLC9A1chr1

27440777

-
5CDS-intronENST00000344008ENST00000490329CASZ1chr1

10753931

-SLC9A1chr1

27436268

-
5CDS-intronENST00000344008ENST00000490329CASZ1chr1

10753930

-SLC9A1chr1

27440777

-
5CDS-intronENST00000344008ENST00000490329CASZ1chr1

10753931

-SLC9A1chr1

27440777

-
5CDS-intronENST00000344008ENST00000545949CASZ1chr1

10753930

-SLC9A1chr1

27440777

-
5CDS-intronENST00000344008ENST00000545949CASZ1chr1

10753931

-SLC9A1chr1

27440777

-
5CDS-intronENST00000377022ENST00000374086CASZ1chr1

10753930

-SLC9A1chr1

27440777

-
5CDS-intronENST00000377022ENST00000374086CASZ1chr1

10753931

-SLC9A1chr1

27440777

-
5CDS-intronENST00000377022ENST00000490329CASZ1chr1

10753931

-SLC9A1chr1

27436268

-
5CDS-intronENST00000377022ENST00000490329CASZ1chr1

10753930

-SLC9A1chr1

27440777

-
5CDS-intronENST00000377022ENST00000490329CASZ1chr1

10753931

-SLC9A1chr1

27440777

-
5CDS-intronENST00000377022ENST00000545949CASZ1chr1

10753930

-SLC9A1chr1

27440777

-
5CDS-intronENST00000377022ENST00000545949CASZ1chr1

10753931

-SLC9A1chr1

27440777

-
5UTR-3CDSENST00000478728ENST00000263980CASZ1chr1

10753931

-SLC9A1chr1

27436268

-
5UTR-3CDSENST00000478728ENST00000263980CASZ1chr1

10753930

-SLC9A1chr1

27440777

-
5UTR-3CDSENST00000478728ENST00000263980CASZ1chr1

10753931

-SLC9A1chr1

27440777

-
5UTR-5UTRENST00000478728ENST00000374086CASZ1chr1

10753931

-SLC9A1chr1

27436268

-
5UTR-5UTRENST00000478728ENST00000545949CASZ1chr1

10753931

-SLC9A1chr1

27436268

-
5UTR-intronENST00000478728ENST00000374086CASZ1chr1

10753930

-SLC9A1chr1

27440777

-
5UTR-intronENST00000478728ENST00000374086CASZ1chr1

10753931

-SLC9A1chr1

27440777

-
5UTR-intronENST00000478728ENST00000490329CASZ1chr1

10753931

-SLC9A1chr1

27436268

-
5UTR-intronENST00000478728ENST00000490329CASZ1chr1

10753930

-SLC9A1chr1

27440777

-
5UTR-intronENST00000478728ENST00000490329CASZ1chr1

10753931

-SLC9A1chr1

27440777

-
5UTR-intronENST00000478728ENST00000545949CASZ1chr1

10753930

-SLC9A1chr1

27440777

-
5UTR-intronENST00000478728ENST00000545949CASZ1chr1

10753931

-SLC9A1chr1

27440777

-
Frame-shiftENST00000344008ENST00000263980CASZ1chr1

10753931

-SLC9A1chr1

27436268

-
Frame-shiftENST00000377022ENST00000263980CASZ1chr1

10753931

-SLC9A1chr1

27436268

-
In-frameENST00000344008ENST00000263980CASZ1chr1

10753930

-SLC9A1chr1

27440777

-
In-frameENST00000344008ENST00000263980CASZ1chr1

10753931

-SLC9A1chr1

27440777

-
In-frameENST00000377022ENST00000263980CASZ1chr1

10753930

-SLC9A1chr1

27440777

-
In-frameENST00000377022ENST00000263980CASZ1chr1

10753931

-SLC9A1chr1

27440777

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000377022CASZ1chr110753930-ENST00000263980SLC9A1chr127440777-39223342852429714
ENST00000344008CASZ1chr110753930-ENST00000263980SLC9A1chr127440777-39243362872431714
ENST00000377022CASZ1chr110753931-ENST00000263980SLC9A1chr127440777-39223342852429714
ENST00000344008CASZ1chr110753931-ENST00000263980SLC9A1chr127440777-39243362872431714

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000377022ENST00000263980CASZ1chr110753930-SLC9A1chr127440777-0.0035744950.99642545
ENST00000344008ENST00000263980CASZ1chr110753930-SLC9A1chr127440777-0.0036369870.996363
ENST00000377022ENST00000263980CASZ1chr110753931-SLC9A1chr127440777-0.0035744950.99642545
ENST00000344008ENST00000263980CASZ1chr110753931-SLC9A1chr127440777-0.0036369870.996363

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Fusion Genomic Features for CASZ1-SLC9A1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for CASZ1-SLC9A1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr1:10753931/chr1:27440777)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneSLC9A1chr1:10753930chr1:27440777ENST00000263980012382_402117816.0IntramembraneName%3DH10
TgeneSLC9A1chr1:10753930chr1:27440777ENST0000037408605382_402117556.0IntramembraneName%3DH10
TgeneSLC9A1chr1:10753931chr1:27440777ENST00000263980012382_402117816.0IntramembraneName%3DH10
TgeneSLC9A1chr1:10753931chr1:27440777ENST0000037408605382_402117556.0IntramembraneName%3DH10
TgeneSLC9A1chr1:10753930chr1:27440777ENST00000263980012128_129117816.0Topological domainCytoplasmic
TgeneSLC9A1chr1:10753930chr1:27440777ENST00000263980012150_154117816.0Topological domainExtracellular
TgeneSLC9A1chr1:10753930chr1:27440777ENST00000263980012175_191117816.0Topological domainCytoplasmic
TgeneSLC9A1chr1:10753930chr1:27440777ENST00000263980012212_227117816.0Topological domainExtracellular
TgeneSLC9A1chr1:10753930chr1:27440777ENST00000263980012248_256117816.0Topological domainCytoplasmic
TgeneSLC9A1chr1:10753930chr1:27440777ENST00000263980012277_294117816.0Topological domainExtracellular
TgeneSLC9A1chr1:10753930chr1:27440777ENST00000263980012316_338117816.0Topological domainCytoplasmic
TgeneSLC9A1chr1:10753930chr1:27440777ENST00000263980012359_381117816.0Topological domainExtracellular
TgeneSLC9A1chr1:10753930chr1:27440777ENST00000263980012403_410117816.0Topological domainExtracellular
TgeneSLC9A1chr1:10753930chr1:27440777ENST00000263980012431_448117816.0Topological domainCytoplasmic
TgeneSLC9A1chr1:10753930chr1:27440777ENST00000263980012471_479117816.0Topological domainExtracellular
TgeneSLC9A1chr1:10753930chr1:27440777ENST00000263980012500_815117816.0Topological domainCytoplasmic
TgeneSLC9A1chr1:10753930chr1:27440777ENST0000037408605128_129117556.0Topological domainCytoplasmic
TgeneSLC9A1chr1:10753930chr1:27440777ENST0000037408605150_154117556.0Topological domainExtracellular
TgeneSLC9A1chr1:10753930chr1:27440777ENST0000037408605175_191117556.0Topological domainCytoplasmic
TgeneSLC9A1chr1:10753930chr1:27440777ENST0000037408605212_227117556.0Topological domainExtracellular
TgeneSLC9A1chr1:10753930chr1:27440777ENST0000037408605248_256117556.0Topological domainCytoplasmic
TgeneSLC9A1chr1:10753930chr1:27440777ENST0000037408605277_294117556.0Topological domainExtracellular
TgeneSLC9A1chr1:10753930chr1:27440777ENST0000037408605316_338117556.0Topological domainCytoplasmic
TgeneSLC9A1chr1:10753930chr1:27440777ENST0000037408605359_381117556.0Topological domainExtracellular
TgeneSLC9A1chr1:10753930chr1:27440777ENST0000037408605403_410117556.0Topological domainExtracellular
TgeneSLC9A1chr1:10753930chr1:27440777ENST0000037408605431_448117556.0Topological domainCytoplasmic
TgeneSLC9A1chr1:10753930chr1:27440777ENST0000037408605471_479117556.0Topological domainExtracellular
TgeneSLC9A1chr1:10753930chr1:27440777ENST0000037408605500_815117556.0Topological domainCytoplasmic
TgeneSLC9A1chr1:10753931chr1:27440777ENST00000263980012128_129117816.0Topological domainCytoplasmic
TgeneSLC9A1chr1:10753931chr1:27440777ENST00000263980012150_154117816.0Topological domainExtracellular
TgeneSLC9A1chr1:10753931chr1:27440777ENST00000263980012175_191117816.0Topological domainCytoplasmic
TgeneSLC9A1chr1:10753931chr1:27440777ENST00000263980012212_227117816.0Topological domainExtracellular
TgeneSLC9A1chr1:10753931chr1:27440777ENST00000263980012248_256117816.0Topological domainCytoplasmic
TgeneSLC9A1chr1:10753931chr1:27440777ENST00000263980012277_294117816.0Topological domainExtracellular
TgeneSLC9A1chr1:10753931chr1:27440777ENST00000263980012316_338117816.0Topological domainCytoplasmic
TgeneSLC9A1chr1:10753931chr1:27440777ENST00000263980012359_381117816.0Topological domainExtracellular
TgeneSLC9A1chr1:10753931chr1:27440777ENST00000263980012403_410117816.0Topological domainExtracellular
TgeneSLC9A1chr1:10753931chr1:27440777ENST00000263980012431_448117816.0Topological domainCytoplasmic
TgeneSLC9A1chr1:10753931chr1:27440777ENST00000263980012471_479117816.0Topological domainExtracellular
TgeneSLC9A1chr1:10753931chr1:27440777ENST00000263980012500_815117816.0Topological domainCytoplasmic
TgeneSLC9A1chr1:10753931chr1:27440777ENST0000037408605128_129117556.0Topological domainCytoplasmic
TgeneSLC9A1chr1:10753931chr1:27440777ENST0000037408605150_154117556.0Topological domainExtracellular
TgeneSLC9A1chr1:10753931chr1:27440777ENST0000037408605175_191117556.0Topological domainCytoplasmic
TgeneSLC9A1chr1:10753931chr1:27440777ENST0000037408605212_227117556.0Topological domainExtracellular
TgeneSLC9A1chr1:10753931chr1:27440777ENST0000037408605248_256117556.0Topological domainCytoplasmic
TgeneSLC9A1chr1:10753931chr1:27440777ENST0000037408605277_294117556.0Topological domainExtracellular
TgeneSLC9A1chr1:10753931chr1:27440777ENST0000037408605316_338117556.0Topological domainCytoplasmic
TgeneSLC9A1chr1:10753931chr1:27440777ENST0000037408605359_381117556.0Topological domainExtracellular
TgeneSLC9A1chr1:10753931chr1:27440777ENST0000037408605403_410117556.0Topological domainExtracellular
TgeneSLC9A1chr1:10753931chr1:27440777ENST0000037408605431_448117556.0Topological domainCytoplasmic
TgeneSLC9A1chr1:10753931chr1:27440777ENST0000037408605471_479117556.0Topological domainExtracellular
TgeneSLC9A1chr1:10753931chr1:27440777ENST0000037408605500_815117556.0Topological domainCytoplasmic
TgeneSLC9A1chr1:10753930chr1:27440777ENST00000263980012130_149117816.0TransmembraneHelical%3B Name%3DM3
TgeneSLC9A1chr1:10753930chr1:27440777ENST00000263980012155_174117816.0TransmembraneHelical%3B Name%3DM4
TgeneSLC9A1chr1:10753930chr1:27440777ENST00000263980012192_211117816.0TransmembraneHelical%3B Name%3DM5
TgeneSLC9A1chr1:10753930chr1:27440777ENST00000263980012228_247117816.0TransmembraneHelical%3B Name%3DM6
TgeneSLC9A1chr1:10753930chr1:27440777ENST00000263980012257_276117816.0TransmembraneHelical%3B Name%3DM7
TgeneSLC9A1chr1:10753930chr1:27440777ENST00000263980012295_315117816.0TransmembraneHelical%3B Name%3DM8
TgeneSLC9A1chr1:10753930chr1:27440777ENST00000263980012339_358117816.0TransmembraneHelical%3B Name%3DM9
TgeneSLC9A1chr1:10753930chr1:27440777ENST00000263980012411_430117816.0TransmembraneHelical%3B Name%3DM10
TgeneSLC9A1chr1:10753930chr1:27440777ENST00000263980012449_470117816.0TransmembraneHelical%3B Name%3DM11
TgeneSLC9A1chr1:10753930chr1:27440777ENST00000263980012480_499117816.0TransmembraneHelical%3B Name%3DM12
TgeneSLC9A1chr1:10753930chr1:27440777ENST0000037408605130_149117556.0TransmembraneHelical%3B Name%3DM3
TgeneSLC9A1chr1:10753930chr1:27440777ENST0000037408605155_174117556.0TransmembraneHelical%3B Name%3DM4
TgeneSLC9A1chr1:10753930chr1:27440777ENST0000037408605192_211117556.0TransmembraneHelical%3B Name%3DM5
TgeneSLC9A1chr1:10753930chr1:27440777ENST0000037408605228_247117556.0TransmembraneHelical%3B Name%3DM6
TgeneSLC9A1chr1:10753930chr1:27440777ENST0000037408605257_276117556.0TransmembraneHelical%3B Name%3DM7
TgeneSLC9A1chr1:10753930chr1:27440777ENST0000037408605295_315117556.0TransmembraneHelical%3B Name%3DM8
TgeneSLC9A1chr1:10753930chr1:27440777ENST0000037408605339_358117556.0TransmembraneHelical%3B Name%3DM9
TgeneSLC9A1chr1:10753930chr1:27440777ENST0000037408605411_430117556.0TransmembraneHelical%3B Name%3DM10
TgeneSLC9A1chr1:10753930chr1:27440777ENST0000037408605449_470117556.0TransmembraneHelical%3B Name%3DM11
TgeneSLC9A1chr1:10753930chr1:27440777ENST0000037408605480_499117556.0TransmembraneHelical%3B Name%3DM12
TgeneSLC9A1chr1:10753931chr1:27440777ENST00000263980012130_149117816.0TransmembraneHelical%3B Name%3DM3
TgeneSLC9A1chr1:10753931chr1:27440777ENST00000263980012155_174117816.0TransmembraneHelical%3B Name%3DM4
TgeneSLC9A1chr1:10753931chr1:27440777ENST00000263980012192_211117816.0TransmembraneHelical%3B Name%3DM5
TgeneSLC9A1chr1:10753931chr1:27440777ENST00000263980012228_247117816.0TransmembraneHelical%3B Name%3DM6
TgeneSLC9A1chr1:10753931chr1:27440777ENST00000263980012257_276117816.0TransmembraneHelical%3B Name%3DM7
TgeneSLC9A1chr1:10753931chr1:27440777ENST00000263980012295_315117816.0TransmembraneHelical%3B Name%3DM8
TgeneSLC9A1chr1:10753931chr1:27440777ENST00000263980012339_358117816.0TransmembraneHelical%3B Name%3DM9
TgeneSLC9A1chr1:10753931chr1:27440777ENST00000263980012411_430117816.0TransmembraneHelical%3B Name%3DM10
TgeneSLC9A1chr1:10753931chr1:27440777ENST00000263980012449_470117816.0TransmembraneHelical%3B Name%3DM11
TgeneSLC9A1chr1:10753931chr1:27440777ENST00000263980012480_499117816.0TransmembraneHelical%3B Name%3DM12
TgeneSLC9A1chr1:10753931chr1:27440777ENST0000037408605130_149117556.0TransmembraneHelical%3B Name%3DM3
TgeneSLC9A1chr1:10753931chr1:27440777ENST0000037408605155_174117556.0TransmembraneHelical%3B Name%3DM4
TgeneSLC9A1chr1:10753931chr1:27440777ENST0000037408605192_211117556.0TransmembraneHelical%3B Name%3DM5
TgeneSLC9A1chr1:10753931chr1:27440777ENST0000037408605228_247117556.0TransmembraneHelical%3B Name%3DM6
TgeneSLC9A1chr1:10753931chr1:27440777ENST0000037408605257_276117556.0TransmembraneHelical%3B Name%3DM7
TgeneSLC9A1chr1:10753931chr1:27440777ENST0000037408605295_315117556.0TransmembraneHelical%3B Name%3DM8
TgeneSLC9A1chr1:10753931chr1:27440777ENST0000037408605339_358117556.0TransmembraneHelical%3B Name%3DM9
TgeneSLC9A1chr1:10753931chr1:27440777ENST0000037408605411_430117556.0TransmembraneHelical%3B Name%3DM10
TgeneSLC9A1chr1:10753931chr1:27440777ENST0000037408605449_470117556.0TransmembraneHelical%3B Name%3DM11
TgeneSLC9A1chr1:10753931chr1:27440777ENST0000037408605480_499117556.0TransmembraneHelical%3B Name%3DM12

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCASZ1chr1:10753930chr1:27440777ENST00000344008-4161080_114351167.0Compositional biasNote=Pro-rich
HgeneCASZ1chr1:10753930chr1:27440777ENST00000344008-4161635_167051167.0Compositional biasNote=Ala-rich
HgeneCASZ1chr1:10753930chr1:27440777ENST00000344008-4161672_172951167.0Compositional biasNote=Glu-rich
HgeneCASZ1chr1:10753930chr1:27440777ENST00000344008-4161691_171851167.0Compositional biasNote=Asp-rich
HgeneCASZ1chr1:10753930chr1:27440777ENST00000344008-416384_41751167.0Compositional biasNote=Pro-rich
HgeneCASZ1chr1:10753930chr1:27440777ENST00000377022-4211080_114351760.0Compositional biasNote=Pro-rich
HgeneCASZ1chr1:10753930chr1:27440777ENST00000377022-4211635_167051760.0Compositional biasNote=Ala-rich
HgeneCASZ1chr1:10753930chr1:27440777ENST00000377022-4211672_172951760.0Compositional biasNote=Glu-rich
HgeneCASZ1chr1:10753930chr1:27440777ENST00000377022-4211691_171851760.0Compositional biasNote=Asp-rich
HgeneCASZ1chr1:10753930chr1:27440777ENST00000377022-421384_41751760.0Compositional biasNote=Pro-rich
HgeneCASZ1chr1:10753931chr1:27440777ENST00000344008-4161080_114351167.0Compositional biasNote=Pro-rich
HgeneCASZ1chr1:10753931chr1:27440777ENST00000344008-4161635_167051167.0Compositional biasNote=Ala-rich
HgeneCASZ1chr1:10753931chr1:27440777ENST00000344008-4161672_172951167.0Compositional biasNote=Glu-rich
HgeneCASZ1chr1:10753931chr1:27440777ENST00000344008-4161691_171851167.0Compositional biasNote=Asp-rich
HgeneCASZ1chr1:10753931chr1:27440777ENST00000344008-416384_41751167.0Compositional biasNote=Pro-rich
HgeneCASZ1chr1:10753931chr1:27440777ENST00000377022-4211080_114351760.0Compositional biasNote=Pro-rich
HgeneCASZ1chr1:10753931chr1:27440777ENST00000377022-4211635_167051760.0Compositional biasNote=Ala-rich
HgeneCASZ1chr1:10753931chr1:27440777ENST00000377022-4211672_172951760.0Compositional biasNote=Glu-rich
HgeneCASZ1chr1:10753931chr1:27440777ENST00000377022-4211691_171851760.0Compositional biasNote=Asp-rich
HgeneCASZ1chr1:10753931chr1:27440777ENST00000377022-421384_41751760.0Compositional biasNote=Pro-rich
HgeneCASZ1chr1:10753930chr1:27440777ENST00000344008-4161031_105551167.0Zinc fingerC2H2-type 4
HgeneCASZ1chr1:10753930chr1:27440777ENST00000344008-4161300_132451167.0Zinc fingerC2H2-type 5
HgeneCASZ1chr1:10753930chr1:27440777ENST00000344008-4161457_148151167.0Zinc fingerC2H2-type 6
HgeneCASZ1chr1:10753930chr1:27440777ENST00000344008-4161515_153751167.0Zinc fingerC2H2-type 7
HgeneCASZ1chr1:10753930chr1:27440777ENST00000344008-4161571_159551167.0Zinc fingerC2H2-type 8
HgeneCASZ1chr1:10753930chr1:27440777ENST00000344008-416551_57551167.0Zinc fingerC2H2-type 1
HgeneCASZ1chr1:10753930chr1:27440777ENST00000344008-416610_63451167.0Zinc fingerC2H2-type 2
HgeneCASZ1chr1:10753930chr1:27440777ENST00000344008-416668_69251167.0Zinc fingerC2H2-type 3
HgeneCASZ1chr1:10753930chr1:27440777ENST00000377022-4211031_105551760.0Zinc fingerC2H2-type 4
HgeneCASZ1chr1:10753930chr1:27440777ENST00000377022-4211300_132451760.0Zinc fingerC2H2-type 5
HgeneCASZ1chr1:10753930chr1:27440777ENST00000377022-4211457_148151760.0Zinc fingerC2H2-type 6
HgeneCASZ1chr1:10753930chr1:27440777ENST00000377022-4211515_153751760.0Zinc fingerC2H2-type 7
HgeneCASZ1chr1:10753930chr1:27440777ENST00000377022-4211571_159551760.0Zinc fingerC2H2-type 8
HgeneCASZ1chr1:10753930chr1:27440777ENST00000377022-421551_57551760.0Zinc fingerC2H2-type 1
HgeneCASZ1chr1:10753930chr1:27440777ENST00000377022-421610_63451760.0Zinc fingerC2H2-type 2
HgeneCASZ1chr1:10753930chr1:27440777ENST00000377022-421668_69251760.0Zinc fingerC2H2-type 3
HgeneCASZ1chr1:10753931chr1:27440777ENST00000344008-4161031_105551167.0Zinc fingerC2H2-type 4
HgeneCASZ1chr1:10753931chr1:27440777ENST00000344008-4161300_132451167.0Zinc fingerC2H2-type 5
HgeneCASZ1chr1:10753931chr1:27440777ENST00000344008-4161457_148151167.0Zinc fingerC2H2-type 6
HgeneCASZ1chr1:10753931chr1:27440777ENST00000344008-4161515_153751167.0Zinc fingerC2H2-type 7
HgeneCASZ1chr1:10753931chr1:27440777ENST00000344008-4161571_159551167.0Zinc fingerC2H2-type 8
HgeneCASZ1chr1:10753931chr1:27440777ENST00000344008-416551_57551167.0Zinc fingerC2H2-type 1
HgeneCASZ1chr1:10753931chr1:27440777ENST00000344008-416610_63451167.0Zinc fingerC2H2-type 2
HgeneCASZ1chr1:10753931chr1:27440777ENST00000344008-416668_69251167.0Zinc fingerC2H2-type 3
HgeneCASZ1chr1:10753931chr1:27440777ENST00000377022-4211031_105551760.0Zinc fingerC2H2-type 4
HgeneCASZ1chr1:10753931chr1:27440777ENST00000377022-4211300_132451760.0Zinc fingerC2H2-type 5
HgeneCASZ1chr1:10753931chr1:27440777ENST00000377022-4211457_148151760.0Zinc fingerC2H2-type 6
HgeneCASZ1chr1:10753931chr1:27440777ENST00000377022-4211515_153751760.0Zinc fingerC2H2-type 7
HgeneCASZ1chr1:10753931chr1:27440777ENST00000377022-4211571_159551760.0Zinc fingerC2H2-type 8
HgeneCASZ1chr1:10753931chr1:27440777ENST00000377022-421551_57551760.0Zinc fingerC2H2-type 1
HgeneCASZ1chr1:10753931chr1:27440777ENST00000377022-421610_63451760.0Zinc fingerC2H2-type 2
HgeneCASZ1chr1:10753931chr1:27440777ENST00000377022-421668_69251760.0Zinc fingerC2H2-type 3
TgeneSLC9A1chr1:10753930chr1:27440777ENST000002639800121_12117816.0Topological domainCytoplasmic
TgeneSLC9A1chr1:10753930chr1:27440777ENST0000026398001234_105117816.0Topological domainExtracellular
TgeneSLC9A1chr1:10753930chr1:27440777ENST00000374086051_12117556.0Topological domainCytoplasmic
TgeneSLC9A1chr1:10753930chr1:27440777ENST000003740860534_105117556.0Topological domainExtracellular
TgeneSLC9A1chr1:10753931chr1:27440777ENST000002639800121_12117816.0Topological domainCytoplasmic
TgeneSLC9A1chr1:10753931chr1:27440777ENST0000026398001234_105117816.0Topological domainExtracellular
TgeneSLC9A1chr1:10753931chr1:27440777ENST00000374086051_12117556.0Topological domainCytoplasmic
TgeneSLC9A1chr1:10753931chr1:27440777ENST000003740860534_105117556.0Topological domainExtracellular
TgeneSLC9A1chr1:10753930chr1:27440777ENST00000263980012106_127117816.0TransmembraneHelical%3B Name%3DM2
TgeneSLC9A1chr1:10753930chr1:27440777ENST0000026398001213_33117816.0TransmembraneHelical%3B Name%3DM1
TgeneSLC9A1chr1:10753930chr1:27440777ENST0000037408605106_127117556.0TransmembraneHelical%3B Name%3DM2
TgeneSLC9A1chr1:10753930chr1:27440777ENST000003740860513_33117556.0TransmembraneHelical%3B Name%3DM1
TgeneSLC9A1chr1:10753931chr1:27440777ENST00000263980012106_127117816.0TransmembraneHelical%3B Name%3DM2
TgeneSLC9A1chr1:10753931chr1:27440777ENST0000026398001213_33117816.0TransmembraneHelical%3B Name%3DM1
TgeneSLC9A1chr1:10753931chr1:27440777ENST0000037408605106_127117556.0TransmembraneHelical%3B Name%3DM2
TgeneSLC9A1chr1:10753931chr1:27440777ENST000003740860513_33117556.0TransmembraneHelical%3B Name%3DM1


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Fusion Gene Sequence for CASZ1-SLC9A1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>13293_13293_1_CASZ1-SLC9A1_CASZ1_chr1_10753930_ENST00000344008_SLC9A1_chr1_27440777_ENST00000263980_length(transcript)=3924nt_BP=336nt
GCATGCGCGCCCGCGGCGCTCCATCCCAAACACACACACATTTTTCCCCCGGACTTGGAAAGTCACCCAAAGCCGCCCCAAGTGCAGGCA
AACAGACCTTGCTGACTGAAGGCAAAGACTCCTCCATCCCACCTGCCCTCCCAGCTGCCACGGCCATCGACCCCTCCTTTACAAGGGGCT
CCTGCAACTCCCCAGCAGCACGTGTTGGAATGGACTTCGGACCCTGGCCTCTTGGGATGCAAAGGATGAAGTGACACCCCCAGCTACATC
CGAGGAGGTTCTAGGACCTGCTACGAGAGTTTGGGACCAAGGAGAAGAGAATGGATCTTGGAACAGGTTTCCATGTGATCCCCACTATCT
CAAGCATCGTCCCGGAGAGCTGCCTGCTGATCGTGGTGGGGCTGCTGGTGGGGGGCCTGATCAAGGGTGTAGGCGAGACACCCCCCTTCC
TGCAGTCCGACGTCTTCTTCCTCTTCCTGCTGCCGCCCATCATCCTGGATGCGGGCTACTTCCTGCCACTGCGGCAGTTCACAGAAAACC
TGGGCACCATCCTGATCTTTGCCGTGGTGGGCACGCTGTGGAACGCCTTCTTCCTGGGCGGCCTCATGTACGCCGTGTGCCTGGTGGGCG
GTGAGCAGATCAACAACATCGGCCTCCTGGACAACCTGCTCTTCGGCAGCATCATCTCGGCCGTGGACCCCGTGGCGGTTCTGGCTGTCT
TTGAGGAAATTCACATCAATGAGCTGCTGCACATCCTTGTTTTTGGGGAGTCCTTGCTCAATGACGCCGTCACTGTGGTCCTGTATCACC
TCTTTGAGGAGTTTGCCAACTACGAACACGTGGGCATCGTGGACATCTTCCTCGGCTTCCTGAGCTTCTTCGTGGTGGCCCTGGGCGGGG
TGCTTGTGGGCGTGGTCTACGGGGTCATCGCAGCCTTCACCTCCCGATTTACCTCCCACATCCGGGTCATCGAGCCGCTCTTCGTCTTCC
TCTACAGCTACATGGCCTACTTGTCAGCCGAGCTCTTCCACCTGTCAGGCATCATGGCGCTCATAGCCTCAGGAGTGGTGATGCGCCCCT
ATGTGGAGGCCAACATCTCCCACAAGTCCCACACCACCATCAAATACTTCCTGAAGATGTGGAGCAGCGTCAGCGAGACCCTCATCTTCA
TCTTCCTCGGCGTCTCCACGGTGGCCGGCTCCCACCACTGGAACTGGACCTTCGTCATCAGCACCCTGCTCTTCTGCCTCATCGCCCGCG
TGCTGGGGGTGCTGGGCCTGACCTGGTTCATCAACAAGTTCCGTATCGTGAAGCTGACCCCCAAGGACCAGTTCATCATCGCCTATGGGG
GCCTGCGAGGGGCCATCGCCTTCTCTCTGGGCTACCTCCTGGACAAGAAGCACTTCCCCATGTGTGACCTGTTCCTCACTGCCATCATCA
CTGTCATCTTCTTCACCGTCTTTGTGCAGGGCATGACCATTCGGCCCCTGGTAGACCTGTTGGCTGTGAAGAAAAAGCAAGAGACGAAGC
GCTCCATCAACGAAGAGATCCACACACAGTTCCTGGACCACCTTCTGACAGGCATCGAAGACATCTGTGGCCACTACGGTCACCACCACT
GGAAGGACAAGCTCAACCGGTTTAATAAGAAATATGTGAAGAAGTGTCTGATAGCTGGCGAGCGCTCCAAGGAGCCCCAGCTCATTGCCT
TCTACCACAAGATGGAGATGAAGCAGGCCATCGAGCTGGTGGAGAGCGGGGGCATGGGCAAGATCCCCTCTGCCGTCTCCACCGTCTCCA
TGCAGAACATCCACCCCAAGTCCCTGCCTTCCGAGCGCATCCTGCCAGCACTGTCCAAGGACAAGGAGGAGGAGATCCGCAAAATCCTGA
GGAACAACTTGCAGAAGACCAGGCAGCGGCTGCGGTCCTACAACAGACACACGCTGGTGGCAGACCCCTACGAGGAAGCCTGGAACCAGA
TGCTGCTCCGGAGGCAGAAGGCCCGGCAGCTGGAGCAGAAGATCAACAACTACCTGACGGTGCCAGCCCACAAGCTGGACTCACCCACCA
TGTCTCGGGCCCGCATCGGCTCAGACCCACTGGCCTATGAGCCGAAGGAGGACCTGCCTGTCATCACCATCGACCCGGCTTCCCCGCAGT
CACCCGAGTCTGTGGACCTGGTGAATGAAGAGCTGAAGGGCAAAGTCTTAGGGTTGAGCCGGGATCCTGCAAAGGTGGCTGAGGAGGACG
AGGACGACGATGGGGGCATCATGATGCGGAGCAAGGAGACTTCGTCCCCAGGAACCGACGATGTCTTCACCCCCGCGCCCAGTGACAGCC
CCAGCTCCCAGAGGATACAGCGCTGCCTCAGTGACCCAGGCCCACACCCTGAGCCTGGGGAGGGAGAACCGTTCTTCCCCAAGGGGCAGT
AACACCAGGGCCAGCAGGCAGCGCCTGTCCCCTCACAGACTCTTCCACCAGAGCAGGGGCTGCTGGGGGCTCCCCTTGCCCTTCCTGACC
CGGATTGGCCCTGCCCCTCCCCCTACCGCATGGCAGCTGGGCCCACAGCCCCCACCCCAGCACAGCTCCTCCCCTGCCGCCTCCCGGGAA
GCATCCTCCCCACCAGAGCTGCCTCCCCAATCCATTTGGCAGAACTGCTGGGGCTGGTGAGGCCGGCCCTGCCCCTCCCTAGATCCAGGC
TTCTCCCGGACCTGGACTAGGGCCTCGGAGGCTCCTCCCTCTGCCTCATCCTCCTCCTCATTCAGACCAATCTTAGTTTCTAACCAAAGA
GTCTCTGGCTCAGCTGTGGTCCCACCCAGGAAGGGAGGGAGCTGAGGCCTCCCTTGAGTAGGCCCTGCTTTATCAGGGGACAAACCAGGG
GTACCAGGCACATGGCTGGGGGAGGGACTGCTGACCCACCAAGGTCTCACACTCCTCCTGCCAGCTCTGTCACCCTGGCCACCACCCAAC
CTGTCCTTACTCAGAGCTGCGGGCTGAGGGCATCTCTGAGTGTCTCTGCCTGGAGCAGGGGTGGTTTCTACGGTGACAGTGACGTGACTC
AGAGCTTTTCGAACTGTGCTCCCACGGGGACCACTGGGCCCCTCAGGGGAAGCTGCTAGGGGAAGGACTGGCCGTGGCTCCAGAATGTGC
TGCCTTTTTAAGTTTTGTTTGTTCACACTCCTATATATGATTGTTTGCACAGAGGGCGCTCCTGTTTTTAAAACATTTTGAAAACCCCTG
GCTGAACAGTGCTCTGCCTCTAACTCCCTCCTCACACTCCAGAATTACCCTTCCTCATCTGTGCCTGTCTGTCCAACCCCTCCCCCACGT
CTCTCTGCCTGCTGGGCTCTTAACTGTTGCTCGAAGACTGTGACATCAGAAGTAACTCCCACTCCTAATCAAGAGTCTCTCCAGCCTCAC
AGATGCTGGCCTCTTGGCACCTGCCTAGCTCTTGGGCCTGACCTCCAGTCCTGCTGGCCTGCTCTTACTTCCCCCACCCTGGGTTTGGCC
CCTGGAACCTTTCCCTTGTGTGTACCACACCCTGCCTGCTGTGGAGCCCATTGTGGAGGCGGTGGGGGGGAGAAGGCCTCCCCTGAGGAT
CCCCTGTCCCCTGGGGCTGGTGGATTGGGCAGAATCCTGGGCCCCCAGAGACCTTTGCCCACACACACTCCTTCCCCTTGTCCCTGGGGC
ACTCCCCCAGGATTGTGCAATAGTCAGAGTGTCCCTTTTTGCAGGGGACTGGGCCATGGGTCCTCGGCCCATCTGTCCATCCTCCTCTCC
ATGCAAGTGCTGTTTGGGCAGGAGTCACCATGCAAGGGTGACATCGACAACCACGTACCAAGCCACCGCAGCTGCTGCCACTCTGCTGCC
TGTACAGAAGAAACTGAATCTTTTTCATATTCTAATAAATCAATGTGAGTTTTT

>13293_13293_1_CASZ1-SLC9A1_CASZ1_chr1_10753930_ENST00000344008_SLC9A1_chr1_27440777_ENST00000263980_length(amino acids)=714AA_BP=16
MLREFGTKEKRMDLGTGFHVIPTISSIVPESCLLIVVGLLVGGLIKGVGETPPFLQSDVFFLFLLPPIILDAGYFLPLRQFTENLGTILI
FAVVGTLWNAFFLGGLMYAVCLVGGEQINNIGLLDNLLFGSIISAVDPVAVLAVFEEIHINELLHILVFGESLLNDAVTVVLYHLFEEFA
NYEHVGIVDIFLGFLSFFVVALGGVLVGVVYGVIAAFTSRFTSHIRVIEPLFVFLYSYMAYLSAELFHLSGIMALIASGVVMRPYVEANI
SHKSHTTIKYFLKMWSSVSETLIFIFLGVSTVAGSHHWNWTFVISTLLFCLIARVLGVLGLTWFINKFRIVKLTPKDQFIIAYGGLRGAI
AFSLGYLLDKKHFPMCDLFLTAIITVIFFTVFVQGMTIRPLVDLLAVKKKQETKRSINEEIHTQFLDHLLTGIEDICGHYGHHHWKDKLN
RFNKKYVKKCLIAGERSKEPQLIAFYHKMEMKQAIELVESGGMGKIPSAVSTVSMQNIHPKSLPSERILPALSKDKEEEIRKILRNNLQK
TRQRLRSYNRHTLVADPYEEAWNQMLLRRQKARQLEQKINNYLTVPAHKLDSPTMSRARIGSDPLAYEPKEDLPVITIDPASPQSPESVD
LVNEELKGKVLGLSRDPAKVAEEDEDDDGGIMMRSKETSSPGTDDVFTPAPSDSPSSQRIQRCLSDPGPHPEPGEGEPFFPKGQ

--------------------------------------------------------------
>13293_13293_2_CASZ1-SLC9A1_CASZ1_chr1_10753930_ENST00000377022_SLC9A1_chr1_27440777_ENST00000263980_length(transcript)=3922nt_BP=334nt
ATGCGCGCCCGCGGCGCTCCATCCCAAACACACACACATTTTTCCCCCGGACTTGGAAAGTCACCCAAAGCCGCCCCAAGTGCAGGCAAA
CAGACCTTGCTGACTGAAGGCAAAGACTCCTCCATCCCACCTGCCCTCCCAGCTGCCACGGCCATCGACCCCTCCTTTACAAGGGGCTCC
TGCAACTCCCCAGCAGCACGTGTTGGAATGGACTTCGGACCCTGGCCTCTTGGGATGCAAAGGATGAAGTGACACCCCCAGCTACATCCG
AGGAGGTTCTAGGACCTGCTACGAGAGTTTGGGACCAAGGAGAAGAGAATGGATCTTGGAACAGGTTTCCATGTGATCCCCACTATCTCA
AGCATCGTCCCGGAGAGCTGCCTGCTGATCGTGGTGGGGCTGCTGGTGGGGGGCCTGATCAAGGGTGTAGGCGAGACACCCCCCTTCCTG
CAGTCCGACGTCTTCTTCCTCTTCCTGCTGCCGCCCATCATCCTGGATGCGGGCTACTTCCTGCCACTGCGGCAGTTCACAGAAAACCTG
GGCACCATCCTGATCTTTGCCGTGGTGGGCACGCTGTGGAACGCCTTCTTCCTGGGCGGCCTCATGTACGCCGTGTGCCTGGTGGGCGGT
GAGCAGATCAACAACATCGGCCTCCTGGACAACCTGCTCTTCGGCAGCATCATCTCGGCCGTGGACCCCGTGGCGGTTCTGGCTGTCTTT
GAGGAAATTCACATCAATGAGCTGCTGCACATCCTTGTTTTTGGGGAGTCCTTGCTCAATGACGCCGTCACTGTGGTCCTGTATCACCTC
TTTGAGGAGTTTGCCAACTACGAACACGTGGGCATCGTGGACATCTTCCTCGGCTTCCTGAGCTTCTTCGTGGTGGCCCTGGGCGGGGTG
CTTGTGGGCGTGGTCTACGGGGTCATCGCAGCCTTCACCTCCCGATTTACCTCCCACATCCGGGTCATCGAGCCGCTCTTCGTCTTCCTC
TACAGCTACATGGCCTACTTGTCAGCCGAGCTCTTCCACCTGTCAGGCATCATGGCGCTCATAGCCTCAGGAGTGGTGATGCGCCCCTAT
GTGGAGGCCAACATCTCCCACAAGTCCCACACCACCATCAAATACTTCCTGAAGATGTGGAGCAGCGTCAGCGAGACCCTCATCTTCATC
TTCCTCGGCGTCTCCACGGTGGCCGGCTCCCACCACTGGAACTGGACCTTCGTCATCAGCACCCTGCTCTTCTGCCTCATCGCCCGCGTG
CTGGGGGTGCTGGGCCTGACCTGGTTCATCAACAAGTTCCGTATCGTGAAGCTGACCCCCAAGGACCAGTTCATCATCGCCTATGGGGGC
CTGCGAGGGGCCATCGCCTTCTCTCTGGGCTACCTCCTGGACAAGAAGCACTTCCCCATGTGTGACCTGTTCCTCACTGCCATCATCACT
GTCATCTTCTTCACCGTCTTTGTGCAGGGCATGACCATTCGGCCCCTGGTAGACCTGTTGGCTGTGAAGAAAAAGCAAGAGACGAAGCGC
TCCATCAACGAAGAGATCCACACACAGTTCCTGGACCACCTTCTGACAGGCATCGAAGACATCTGTGGCCACTACGGTCACCACCACTGG
AAGGACAAGCTCAACCGGTTTAATAAGAAATATGTGAAGAAGTGTCTGATAGCTGGCGAGCGCTCCAAGGAGCCCCAGCTCATTGCCTTC
TACCACAAGATGGAGATGAAGCAGGCCATCGAGCTGGTGGAGAGCGGGGGCATGGGCAAGATCCCCTCTGCCGTCTCCACCGTCTCCATG
CAGAACATCCACCCCAAGTCCCTGCCTTCCGAGCGCATCCTGCCAGCACTGTCCAAGGACAAGGAGGAGGAGATCCGCAAAATCCTGAGG
AACAACTTGCAGAAGACCAGGCAGCGGCTGCGGTCCTACAACAGACACACGCTGGTGGCAGACCCCTACGAGGAAGCCTGGAACCAGATG
CTGCTCCGGAGGCAGAAGGCCCGGCAGCTGGAGCAGAAGATCAACAACTACCTGACGGTGCCAGCCCACAAGCTGGACTCACCCACCATG
TCTCGGGCCCGCATCGGCTCAGACCCACTGGCCTATGAGCCGAAGGAGGACCTGCCTGTCATCACCATCGACCCGGCTTCCCCGCAGTCA
CCCGAGTCTGTGGACCTGGTGAATGAAGAGCTGAAGGGCAAAGTCTTAGGGTTGAGCCGGGATCCTGCAAAGGTGGCTGAGGAGGACGAG
GACGACGATGGGGGCATCATGATGCGGAGCAAGGAGACTTCGTCCCCAGGAACCGACGATGTCTTCACCCCCGCGCCCAGTGACAGCCCC
AGCTCCCAGAGGATACAGCGCTGCCTCAGTGACCCAGGCCCACACCCTGAGCCTGGGGAGGGAGAACCGTTCTTCCCCAAGGGGCAGTAA
CACCAGGGCCAGCAGGCAGCGCCTGTCCCCTCACAGACTCTTCCACCAGAGCAGGGGCTGCTGGGGGCTCCCCTTGCCCTTCCTGACCCG
GATTGGCCCTGCCCCTCCCCCTACCGCATGGCAGCTGGGCCCACAGCCCCCACCCCAGCACAGCTCCTCCCCTGCCGCCTCCCGGGAAGC
ATCCTCCCCACCAGAGCTGCCTCCCCAATCCATTTGGCAGAACTGCTGGGGCTGGTGAGGCCGGCCCTGCCCCTCCCTAGATCCAGGCTT
CTCCCGGACCTGGACTAGGGCCTCGGAGGCTCCTCCCTCTGCCTCATCCTCCTCCTCATTCAGACCAATCTTAGTTTCTAACCAAAGAGT
CTCTGGCTCAGCTGTGGTCCCACCCAGGAAGGGAGGGAGCTGAGGCCTCCCTTGAGTAGGCCCTGCTTTATCAGGGGACAAACCAGGGGT
ACCAGGCACATGGCTGGGGGAGGGACTGCTGACCCACCAAGGTCTCACACTCCTCCTGCCAGCTCTGTCACCCTGGCCACCACCCAACCT
GTCCTTACTCAGAGCTGCGGGCTGAGGGCATCTCTGAGTGTCTCTGCCTGGAGCAGGGGTGGTTTCTACGGTGACAGTGACGTGACTCAG
AGCTTTTCGAACTGTGCTCCCACGGGGACCACTGGGCCCCTCAGGGGAAGCTGCTAGGGGAAGGACTGGCCGTGGCTCCAGAATGTGCTG
CCTTTTTAAGTTTTGTTTGTTCACACTCCTATATATGATTGTTTGCACAGAGGGCGCTCCTGTTTTTAAAACATTTTGAAAACCCCTGGC
TGAACAGTGCTCTGCCTCTAACTCCCTCCTCACACTCCAGAATTACCCTTCCTCATCTGTGCCTGTCTGTCCAACCCCTCCCCCACGTCT
CTCTGCCTGCTGGGCTCTTAACTGTTGCTCGAAGACTGTGACATCAGAAGTAACTCCCACTCCTAATCAAGAGTCTCTCCAGCCTCACAG
ATGCTGGCCTCTTGGCACCTGCCTAGCTCTTGGGCCTGACCTCCAGTCCTGCTGGCCTGCTCTTACTTCCCCCACCCTGGGTTTGGCCCC
TGGAACCTTTCCCTTGTGTGTACCACACCCTGCCTGCTGTGGAGCCCATTGTGGAGGCGGTGGGGGGGAGAAGGCCTCCCCTGAGGATCC
CCTGTCCCCTGGGGCTGGTGGATTGGGCAGAATCCTGGGCCCCCAGAGACCTTTGCCCACACACACTCCTTCCCCTTGTCCCTGGGGCAC
TCCCCCAGGATTGTGCAATAGTCAGAGTGTCCCTTTTTGCAGGGGACTGGGCCATGGGTCCTCGGCCCATCTGTCCATCCTCCTCTCCAT
GCAAGTGCTGTTTGGGCAGGAGTCACCATGCAAGGGTGACATCGACAACCACGTACCAAGCCACCGCAGCTGCTGCCACTCTGCTGCCTG
TACAGAAGAAACTGAATCTTTTTCATATTCTAATAAATCAATGTGAGTTTTT

>13293_13293_2_CASZ1-SLC9A1_CASZ1_chr1_10753930_ENST00000377022_SLC9A1_chr1_27440777_ENST00000263980_length(amino acids)=714AA_BP=16
MLREFGTKEKRMDLGTGFHVIPTISSIVPESCLLIVVGLLVGGLIKGVGETPPFLQSDVFFLFLLPPIILDAGYFLPLRQFTENLGTILI
FAVVGTLWNAFFLGGLMYAVCLVGGEQINNIGLLDNLLFGSIISAVDPVAVLAVFEEIHINELLHILVFGESLLNDAVTVVLYHLFEEFA
NYEHVGIVDIFLGFLSFFVVALGGVLVGVVYGVIAAFTSRFTSHIRVIEPLFVFLYSYMAYLSAELFHLSGIMALIASGVVMRPYVEANI
SHKSHTTIKYFLKMWSSVSETLIFIFLGVSTVAGSHHWNWTFVISTLLFCLIARVLGVLGLTWFINKFRIVKLTPKDQFIIAYGGLRGAI
AFSLGYLLDKKHFPMCDLFLTAIITVIFFTVFVQGMTIRPLVDLLAVKKKQETKRSINEEIHTQFLDHLLTGIEDICGHYGHHHWKDKLN
RFNKKYVKKCLIAGERSKEPQLIAFYHKMEMKQAIELVESGGMGKIPSAVSTVSMQNIHPKSLPSERILPALSKDKEEEIRKILRNNLQK
TRQRLRSYNRHTLVADPYEEAWNQMLLRRQKARQLEQKINNYLTVPAHKLDSPTMSRARIGSDPLAYEPKEDLPVITIDPASPQSPESVD
LVNEELKGKVLGLSRDPAKVAEEDEDDDGGIMMRSKETSSPGTDDVFTPAPSDSPSSQRIQRCLSDPGPHPEPGEGEPFFPKGQ

--------------------------------------------------------------
>13293_13293_3_CASZ1-SLC9A1_CASZ1_chr1_10753931_ENST00000344008_SLC9A1_chr1_27440777_ENST00000263980_length(transcript)=3924nt_BP=336nt
GCATGCGCGCCCGCGGCGCTCCATCCCAAACACACACACATTTTTCCCCCGGACTTGGAAAGTCACCCAAAGCCGCCCCAAGTGCAGGCA
AACAGACCTTGCTGACTGAAGGCAAAGACTCCTCCATCCCACCTGCCCTCCCAGCTGCCACGGCCATCGACCCCTCCTTTACAAGGGGCT
CCTGCAACTCCCCAGCAGCACGTGTTGGAATGGACTTCGGACCCTGGCCTCTTGGGATGCAAAGGATGAAGTGACACCCCCAGCTACATC
CGAGGAGGTTCTAGGACCTGCTACGAGAGTTTGGGACCAAGGAGAAGAGAATGGATCTTGGAACAGGTTTCCATGTGATCCCCACTATCT
CAAGCATCGTCCCGGAGAGCTGCCTGCTGATCGTGGTGGGGCTGCTGGTGGGGGGCCTGATCAAGGGTGTAGGCGAGACACCCCCCTTCC
TGCAGTCCGACGTCTTCTTCCTCTTCCTGCTGCCGCCCATCATCCTGGATGCGGGCTACTTCCTGCCACTGCGGCAGTTCACAGAAAACC
TGGGCACCATCCTGATCTTTGCCGTGGTGGGCACGCTGTGGAACGCCTTCTTCCTGGGCGGCCTCATGTACGCCGTGTGCCTGGTGGGCG
GTGAGCAGATCAACAACATCGGCCTCCTGGACAACCTGCTCTTCGGCAGCATCATCTCGGCCGTGGACCCCGTGGCGGTTCTGGCTGTCT
TTGAGGAAATTCACATCAATGAGCTGCTGCACATCCTTGTTTTTGGGGAGTCCTTGCTCAATGACGCCGTCACTGTGGTCCTGTATCACC
TCTTTGAGGAGTTTGCCAACTACGAACACGTGGGCATCGTGGACATCTTCCTCGGCTTCCTGAGCTTCTTCGTGGTGGCCCTGGGCGGGG
TGCTTGTGGGCGTGGTCTACGGGGTCATCGCAGCCTTCACCTCCCGATTTACCTCCCACATCCGGGTCATCGAGCCGCTCTTCGTCTTCC
TCTACAGCTACATGGCCTACTTGTCAGCCGAGCTCTTCCACCTGTCAGGCATCATGGCGCTCATAGCCTCAGGAGTGGTGATGCGCCCCT
ATGTGGAGGCCAACATCTCCCACAAGTCCCACACCACCATCAAATACTTCCTGAAGATGTGGAGCAGCGTCAGCGAGACCCTCATCTTCA
TCTTCCTCGGCGTCTCCACGGTGGCCGGCTCCCACCACTGGAACTGGACCTTCGTCATCAGCACCCTGCTCTTCTGCCTCATCGCCCGCG
TGCTGGGGGTGCTGGGCCTGACCTGGTTCATCAACAAGTTCCGTATCGTGAAGCTGACCCCCAAGGACCAGTTCATCATCGCCTATGGGG
GCCTGCGAGGGGCCATCGCCTTCTCTCTGGGCTACCTCCTGGACAAGAAGCACTTCCCCATGTGTGACCTGTTCCTCACTGCCATCATCA
CTGTCATCTTCTTCACCGTCTTTGTGCAGGGCATGACCATTCGGCCCCTGGTAGACCTGTTGGCTGTGAAGAAAAAGCAAGAGACGAAGC
GCTCCATCAACGAAGAGATCCACACACAGTTCCTGGACCACCTTCTGACAGGCATCGAAGACATCTGTGGCCACTACGGTCACCACCACT
GGAAGGACAAGCTCAACCGGTTTAATAAGAAATATGTGAAGAAGTGTCTGATAGCTGGCGAGCGCTCCAAGGAGCCCCAGCTCATTGCCT
TCTACCACAAGATGGAGATGAAGCAGGCCATCGAGCTGGTGGAGAGCGGGGGCATGGGCAAGATCCCCTCTGCCGTCTCCACCGTCTCCA
TGCAGAACATCCACCCCAAGTCCCTGCCTTCCGAGCGCATCCTGCCAGCACTGTCCAAGGACAAGGAGGAGGAGATCCGCAAAATCCTGA
GGAACAACTTGCAGAAGACCAGGCAGCGGCTGCGGTCCTACAACAGACACACGCTGGTGGCAGACCCCTACGAGGAAGCCTGGAACCAGA
TGCTGCTCCGGAGGCAGAAGGCCCGGCAGCTGGAGCAGAAGATCAACAACTACCTGACGGTGCCAGCCCACAAGCTGGACTCACCCACCA
TGTCTCGGGCCCGCATCGGCTCAGACCCACTGGCCTATGAGCCGAAGGAGGACCTGCCTGTCATCACCATCGACCCGGCTTCCCCGCAGT
CACCCGAGTCTGTGGACCTGGTGAATGAAGAGCTGAAGGGCAAAGTCTTAGGGTTGAGCCGGGATCCTGCAAAGGTGGCTGAGGAGGACG
AGGACGACGATGGGGGCATCATGATGCGGAGCAAGGAGACTTCGTCCCCAGGAACCGACGATGTCTTCACCCCCGCGCCCAGTGACAGCC
CCAGCTCCCAGAGGATACAGCGCTGCCTCAGTGACCCAGGCCCACACCCTGAGCCTGGGGAGGGAGAACCGTTCTTCCCCAAGGGGCAGT
AACACCAGGGCCAGCAGGCAGCGCCTGTCCCCTCACAGACTCTTCCACCAGAGCAGGGGCTGCTGGGGGCTCCCCTTGCCCTTCCTGACC
CGGATTGGCCCTGCCCCTCCCCCTACCGCATGGCAGCTGGGCCCACAGCCCCCACCCCAGCACAGCTCCTCCCCTGCCGCCTCCCGGGAA
GCATCCTCCCCACCAGAGCTGCCTCCCCAATCCATTTGGCAGAACTGCTGGGGCTGGTGAGGCCGGCCCTGCCCCTCCCTAGATCCAGGC
TTCTCCCGGACCTGGACTAGGGCCTCGGAGGCTCCTCCCTCTGCCTCATCCTCCTCCTCATTCAGACCAATCTTAGTTTCTAACCAAAGA
GTCTCTGGCTCAGCTGTGGTCCCACCCAGGAAGGGAGGGAGCTGAGGCCTCCCTTGAGTAGGCCCTGCTTTATCAGGGGACAAACCAGGG
GTACCAGGCACATGGCTGGGGGAGGGACTGCTGACCCACCAAGGTCTCACACTCCTCCTGCCAGCTCTGTCACCCTGGCCACCACCCAAC
CTGTCCTTACTCAGAGCTGCGGGCTGAGGGCATCTCTGAGTGTCTCTGCCTGGAGCAGGGGTGGTTTCTACGGTGACAGTGACGTGACTC
AGAGCTTTTCGAACTGTGCTCCCACGGGGACCACTGGGCCCCTCAGGGGAAGCTGCTAGGGGAAGGACTGGCCGTGGCTCCAGAATGTGC
TGCCTTTTTAAGTTTTGTTTGTTCACACTCCTATATATGATTGTTTGCACAGAGGGCGCTCCTGTTTTTAAAACATTTTGAAAACCCCTG
GCTGAACAGTGCTCTGCCTCTAACTCCCTCCTCACACTCCAGAATTACCCTTCCTCATCTGTGCCTGTCTGTCCAACCCCTCCCCCACGT
CTCTCTGCCTGCTGGGCTCTTAACTGTTGCTCGAAGACTGTGACATCAGAAGTAACTCCCACTCCTAATCAAGAGTCTCTCCAGCCTCAC
AGATGCTGGCCTCTTGGCACCTGCCTAGCTCTTGGGCCTGACCTCCAGTCCTGCTGGCCTGCTCTTACTTCCCCCACCCTGGGTTTGGCC
CCTGGAACCTTTCCCTTGTGTGTACCACACCCTGCCTGCTGTGGAGCCCATTGTGGAGGCGGTGGGGGGGAGAAGGCCTCCCCTGAGGAT
CCCCTGTCCCCTGGGGCTGGTGGATTGGGCAGAATCCTGGGCCCCCAGAGACCTTTGCCCACACACACTCCTTCCCCTTGTCCCTGGGGC
ACTCCCCCAGGATTGTGCAATAGTCAGAGTGTCCCTTTTTGCAGGGGACTGGGCCATGGGTCCTCGGCCCATCTGTCCATCCTCCTCTCC
ATGCAAGTGCTGTTTGGGCAGGAGTCACCATGCAAGGGTGACATCGACAACCACGTACCAAGCCACCGCAGCTGCTGCCACTCTGCTGCC
TGTACAGAAGAAACTGAATCTTTTTCATATTCTAATAAATCAATGTGAGTTTTT

>13293_13293_3_CASZ1-SLC9A1_CASZ1_chr1_10753931_ENST00000344008_SLC9A1_chr1_27440777_ENST00000263980_length(amino acids)=714AA_BP=16
MLREFGTKEKRMDLGTGFHVIPTISSIVPESCLLIVVGLLVGGLIKGVGETPPFLQSDVFFLFLLPPIILDAGYFLPLRQFTENLGTILI
FAVVGTLWNAFFLGGLMYAVCLVGGEQINNIGLLDNLLFGSIISAVDPVAVLAVFEEIHINELLHILVFGESLLNDAVTVVLYHLFEEFA
NYEHVGIVDIFLGFLSFFVVALGGVLVGVVYGVIAAFTSRFTSHIRVIEPLFVFLYSYMAYLSAELFHLSGIMALIASGVVMRPYVEANI
SHKSHTTIKYFLKMWSSVSETLIFIFLGVSTVAGSHHWNWTFVISTLLFCLIARVLGVLGLTWFINKFRIVKLTPKDQFIIAYGGLRGAI
AFSLGYLLDKKHFPMCDLFLTAIITVIFFTVFVQGMTIRPLVDLLAVKKKQETKRSINEEIHTQFLDHLLTGIEDICGHYGHHHWKDKLN
RFNKKYVKKCLIAGERSKEPQLIAFYHKMEMKQAIELVESGGMGKIPSAVSTVSMQNIHPKSLPSERILPALSKDKEEEIRKILRNNLQK
TRQRLRSYNRHTLVADPYEEAWNQMLLRRQKARQLEQKINNYLTVPAHKLDSPTMSRARIGSDPLAYEPKEDLPVITIDPASPQSPESVD
LVNEELKGKVLGLSRDPAKVAEEDEDDDGGIMMRSKETSSPGTDDVFTPAPSDSPSSQRIQRCLSDPGPHPEPGEGEPFFPKGQ

--------------------------------------------------------------
>13293_13293_4_CASZ1-SLC9A1_CASZ1_chr1_10753931_ENST00000377022_SLC9A1_chr1_27440777_ENST00000263980_length(transcript)=3922nt_BP=334nt
ATGCGCGCCCGCGGCGCTCCATCCCAAACACACACACATTTTTCCCCCGGACTTGGAAAGTCACCCAAAGCCGCCCCAAGTGCAGGCAAA
CAGACCTTGCTGACTGAAGGCAAAGACTCCTCCATCCCACCTGCCCTCCCAGCTGCCACGGCCATCGACCCCTCCTTTACAAGGGGCTCC
TGCAACTCCCCAGCAGCACGTGTTGGAATGGACTTCGGACCCTGGCCTCTTGGGATGCAAAGGATGAAGTGACACCCCCAGCTACATCCG
AGGAGGTTCTAGGACCTGCTACGAGAGTTTGGGACCAAGGAGAAGAGAATGGATCTTGGAACAGGTTTCCATGTGATCCCCACTATCTCA
AGCATCGTCCCGGAGAGCTGCCTGCTGATCGTGGTGGGGCTGCTGGTGGGGGGCCTGATCAAGGGTGTAGGCGAGACACCCCCCTTCCTG
CAGTCCGACGTCTTCTTCCTCTTCCTGCTGCCGCCCATCATCCTGGATGCGGGCTACTTCCTGCCACTGCGGCAGTTCACAGAAAACCTG
GGCACCATCCTGATCTTTGCCGTGGTGGGCACGCTGTGGAACGCCTTCTTCCTGGGCGGCCTCATGTACGCCGTGTGCCTGGTGGGCGGT
GAGCAGATCAACAACATCGGCCTCCTGGACAACCTGCTCTTCGGCAGCATCATCTCGGCCGTGGACCCCGTGGCGGTTCTGGCTGTCTTT
GAGGAAATTCACATCAATGAGCTGCTGCACATCCTTGTTTTTGGGGAGTCCTTGCTCAATGACGCCGTCACTGTGGTCCTGTATCACCTC
TTTGAGGAGTTTGCCAACTACGAACACGTGGGCATCGTGGACATCTTCCTCGGCTTCCTGAGCTTCTTCGTGGTGGCCCTGGGCGGGGTG
CTTGTGGGCGTGGTCTACGGGGTCATCGCAGCCTTCACCTCCCGATTTACCTCCCACATCCGGGTCATCGAGCCGCTCTTCGTCTTCCTC
TACAGCTACATGGCCTACTTGTCAGCCGAGCTCTTCCACCTGTCAGGCATCATGGCGCTCATAGCCTCAGGAGTGGTGATGCGCCCCTAT
GTGGAGGCCAACATCTCCCACAAGTCCCACACCACCATCAAATACTTCCTGAAGATGTGGAGCAGCGTCAGCGAGACCCTCATCTTCATC
TTCCTCGGCGTCTCCACGGTGGCCGGCTCCCACCACTGGAACTGGACCTTCGTCATCAGCACCCTGCTCTTCTGCCTCATCGCCCGCGTG
CTGGGGGTGCTGGGCCTGACCTGGTTCATCAACAAGTTCCGTATCGTGAAGCTGACCCCCAAGGACCAGTTCATCATCGCCTATGGGGGC
CTGCGAGGGGCCATCGCCTTCTCTCTGGGCTACCTCCTGGACAAGAAGCACTTCCCCATGTGTGACCTGTTCCTCACTGCCATCATCACT
GTCATCTTCTTCACCGTCTTTGTGCAGGGCATGACCATTCGGCCCCTGGTAGACCTGTTGGCTGTGAAGAAAAAGCAAGAGACGAAGCGC
TCCATCAACGAAGAGATCCACACACAGTTCCTGGACCACCTTCTGACAGGCATCGAAGACATCTGTGGCCACTACGGTCACCACCACTGG
AAGGACAAGCTCAACCGGTTTAATAAGAAATATGTGAAGAAGTGTCTGATAGCTGGCGAGCGCTCCAAGGAGCCCCAGCTCATTGCCTTC
TACCACAAGATGGAGATGAAGCAGGCCATCGAGCTGGTGGAGAGCGGGGGCATGGGCAAGATCCCCTCTGCCGTCTCCACCGTCTCCATG
CAGAACATCCACCCCAAGTCCCTGCCTTCCGAGCGCATCCTGCCAGCACTGTCCAAGGACAAGGAGGAGGAGATCCGCAAAATCCTGAGG
AACAACTTGCAGAAGACCAGGCAGCGGCTGCGGTCCTACAACAGACACACGCTGGTGGCAGACCCCTACGAGGAAGCCTGGAACCAGATG
CTGCTCCGGAGGCAGAAGGCCCGGCAGCTGGAGCAGAAGATCAACAACTACCTGACGGTGCCAGCCCACAAGCTGGACTCACCCACCATG
TCTCGGGCCCGCATCGGCTCAGACCCACTGGCCTATGAGCCGAAGGAGGACCTGCCTGTCATCACCATCGACCCGGCTTCCCCGCAGTCA
CCCGAGTCTGTGGACCTGGTGAATGAAGAGCTGAAGGGCAAAGTCTTAGGGTTGAGCCGGGATCCTGCAAAGGTGGCTGAGGAGGACGAG
GACGACGATGGGGGCATCATGATGCGGAGCAAGGAGACTTCGTCCCCAGGAACCGACGATGTCTTCACCCCCGCGCCCAGTGACAGCCCC
AGCTCCCAGAGGATACAGCGCTGCCTCAGTGACCCAGGCCCACACCCTGAGCCTGGGGAGGGAGAACCGTTCTTCCCCAAGGGGCAGTAA
CACCAGGGCCAGCAGGCAGCGCCTGTCCCCTCACAGACTCTTCCACCAGAGCAGGGGCTGCTGGGGGCTCCCCTTGCCCTTCCTGACCCG
GATTGGCCCTGCCCCTCCCCCTACCGCATGGCAGCTGGGCCCACAGCCCCCACCCCAGCACAGCTCCTCCCCTGCCGCCTCCCGGGAAGC
ATCCTCCCCACCAGAGCTGCCTCCCCAATCCATTTGGCAGAACTGCTGGGGCTGGTGAGGCCGGCCCTGCCCCTCCCTAGATCCAGGCTT
CTCCCGGACCTGGACTAGGGCCTCGGAGGCTCCTCCCTCTGCCTCATCCTCCTCCTCATTCAGACCAATCTTAGTTTCTAACCAAAGAGT
CTCTGGCTCAGCTGTGGTCCCACCCAGGAAGGGAGGGAGCTGAGGCCTCCCTTGAGTAGGCCCTGCTTTATCAGGGGACAAACCAGGGGT
ACCAGGCACATGGCTGGGGGAGGGACTGCTGACCCACCAAGGTCTCACACTCCTCCTGCCAGCTCTGTCACCCTGGCCACCACCCAACCT
GTCCTTACTCAGAGCTGCGGGCTGAGGGCATCTCTGAGTGTCTCTGCCTGGAGCAGGGGTGGTTTCTACGGTGACAGTGACGTGACTCAG
AGCTTTTCGAACTGTGCTCCCACGGGGACCACTGGGCCCCTCAGGGGAAGCTGCTAGGGGAAGGACTGGCCGTGGCTCCAGAATGTGCTG
CCTTTTTAAGTTTTGTTTGTTCACACTCCTATATATGATTGTTTGCACAGAGGGCGCTCCTGTTTTTAAAACATTTTGAAAACCCCTGGC
TGAACAGTGCTCTGCCTCTAACTCCCTCCTCACACTCCAGAATTACCCTTCCTCATCTGTGCCTGTCTGTCCAACCCCTCCCCCACGTCT
CTCTGCCTGCTGGGCTCTTAACTGTTGCTCGAAGACTGTGACATCAGAAGTAACTCCCACTCCTAATCAAGAGTCTCTCCAGCCTCACAG
ATGCTGGCCTCTTGGCACCTGCCTAGCTCTTGGGCCTGACCTCCAGTCCTGCTGGCCTGCTCTTACTTCCCCCACCCTGGGTTTGGCCCC
TGGAACCTTTCCCTTGTGTGTACCACACCCTGCCTGCTGTGGAGCCCATTGTGGAGGCGGTGGGGGGGAGAAGGCCTCCCCTGAGGATCC
CCTGTCCCCTGGGGCTGGTGGATTGGGCAGAATCCTGGGCCCCCAGAGACCTTTGCCCACACACACTCCTTCCCCTTGTCCCTGGGGCAC
TCCCCCAGGATTGTGCAATAGTCAGAGTGTCCCTTTTTGCAGGGGACTGGGCCATGGGTCCTCGGCCCATCTGTCCATCCTCCTCTCCAT
GCAAGTGCTGTTTGGGCAGGAGTCACCATGCAAGGGTGACATCGACAACCACGTACCAAGCCACCGCAGCTGCTGCCACTCTGCTGCCTG
TACAGAAGAAACTGAATCTTTTTCATATTCTAATAAATCAATGTGAGTTTTT

>13293_13293_4_CASZ1-SLC9A1_CASZ1_chr1_10753931_ENST00000377022_SLC9A1_chr1_27440777_ENST00000263980_length(amino acids)=714AA_BP=16
MLREFGTKEKRMDLGTGFHVIPTISSIVPESCLLIVVGLLVGGLIKGVGETPPFLQSDVFFLFLLPPIILDAGYFLPLRQFTENLGTILI
FAVVGTLWNAFFLGGLMYAVCLVGGEQINNIGLLDNLLFGSIISAVDPVAVLAVFEEIHINELLHILVFGESLLNDAVTVVLYHLFEEFA
NYEHVGIVDIFLGFLSFFVVALGGVLVGVVYGVIAAFTSRFTSHIRVIEPLFVFLYSYMAYLSAELFHLSGIMALIASGVVMRPYVEANI
SHKSHTTIKYFLKMWSSVSETLIFIFLGVSTVAGSHHWNWTFVISTLLFCLIARVLGVLGLTWFINKFRIVKLTPKDQFIIAYGGLRGAI
AFSLGYLLDKKHFPMCDLFLTAIITVIFFTVFVQGMTIRPLVDLLAVKKKQETKRSINEEIHTQFLDHLLTGIEDICGHYGHHHWKDKLN
RFNKKYVKKCLIAGERSKEPQLIAFYHKMEMKQAIELVESGGMGKIPSAVSTVSMQNIHPKSLPSERILPALSKDKEEEIRKILRNNLQK
TRQRLRSYNRHTLVADPYEEAWNQMLLRRQKARQLEQKINNYLTVPAHKLDSPTMSRARIGSDPLAYEPKEDLPVITIDPASPQSPESVD
LVNEELKGKVLGLSRDPAKVAEEDEDDDGGIMMRSKETSSPGTDDVFTPAPSDSPSSQRIQRCLSDPGPHPEPGEGEPFFPKGQ

--------------------------------------------------------------

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Fusion Gene PPI Analysis for CASZ1-SLC9A1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneSLC9A1chr1:10753930chr1:27440777ENST00000263980012515_545117.33333333333333816.0CHP2
TgeneSLC9A1chr1:10753930chr1:27440777ENST0000037408605515_545117.33333333333333556.0CHP2
TgeneSLC9A1chr1:10753931chr1:27440777ENST00000263980012515_545117.33333333333333816.0CHP2
TgeneSLC9A1chr1:10753931chr1:27440777ENST0000037408605515_545117.33333333333333556.0CHP2
TgeneSLC9A1chr1:10753930chr1:27440777ENST00000263980012633_815117.33333333333333816.0TESC
TgeneSLC9A1chr1:10753930chr1:27440777ENST0000037408605633_815117.33333333333333556.0TESC
TgeneSLC9A1chr1:10753931chr1:27440777ENST00000263980012633_815117.33333333333333816.0TESC
TgeneSLC9A1chr1:10753931chr1:27440777ENST0000037408605633_815117.33333333333333556.0TESC
TgeneSLC9A1chr1:10753930chr1:27440777ENST00000263980012503_545117.33333333333333816.0TESC
TgeneSLC9A1chr1:10753930chr1:27440777ENST0000037408605503_545117.33333333333333556.0TESC
TgeneSLC9A1chr1:10753931chr1:27440777ENST00000263980012503_545117.33333333333333816.0TESC
TgeneSLC9A1chr1:10753931chr1:27440777ENST0000037408605503_545117.33333333333333556.0TESC


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CASZ1-SLC9A1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CASZ1-SLC9A1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneCASZ1C0004238Atrial Fibrillation2CTD_human
HgeneCASZ1C0235480Paroxysmal atrial fibrillation2CTD_human
HgeneCASZ1C2585653Persistent atrial fibrillation2CTD_human
HgeneCASZ1C3468561familial atrial fibrillation2CTD_human
HgeneCASZ1C0033578Prostatic Neoplasms1CTD_human
HgeneCASZ1C0038454Cerebrovascular accident1CTD_human
HgeneCASZ1C0376358Malignant neoplasm of prostate1CTD_human
HgeneCASZ1C0751956Acute Cerebrovascular Accidents1CTD_human
TgeneC4225383LICHTENSTEIN-KNORR SYNDROME2CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
TgeneC0002152Alloxan Diabetes1CTD_human
TgeneC0004763Barrett Esophagus1CTD_human
TgeneC0007194Hypertrophic Cardiomyopathy1CTD_human
TgeneC0011853Diabetes Mellitus, Experimental1CTD_human
TgeneC0013604Edema1CTD_human
TgeneC0018801Heart failure1CTD_human
TgeneC0018802Congestive heart failure1CTD_human
TgeneC0023212Left-Sided Heart Failure1CTD_human
TgeneC0030193Pain1CTD_human
TgeneC0035126Reperfusion Injury1CTD_human
TgeneC0036982Shock, Hemorrhagic1CTD_human
TgeneC0038433Streptozotocin Diabetes1CTD_human
TgeneC0151603Anasarca1CTD_human
TgeneC0234230Pain, Burning1CTD_human
TgeneC0234238Ache1CTD_human
TgeneC0234254Radiating pain1CTD_human
TgeneC0235527Heart Failure, Right-Sided1CTD_human
TgeneC0458257Pain, Splitting1CTD_human
TgeneC0458259Pain, Crushing1CTD_human
TgeneC0600519Ventricular Remodeling1CTD_human
TgeneC0600520Left Ventricle Remodeling1CTD_human
TgeneC0751407Pain, Migratory1CTD_human
TgeneC0751408Suffering, Physical1CTD_human
TgeneC1258085Barrett Epithelium1CTD_human
TgeneC1959583Myocardial Failure1CTD_human
TgeneC1961112Heart Decompensation1CTD_human
TgeneC4551472Hypertrophic obstructive cardiomyopathy1CTD_human