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in Kim Lab

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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:PLEKHB2-BIRC6 (FusionGDB2 ID:HG55041TG57448)

Fusion Gene Summary for PLEKHB2-BIRC6

check button Fusion gene summary
Fusion gene informationFusion gene name: PLEKHB2-BIRC6
Fusion gene ID: hg55041tg57448
HgeneTgene
Gene symbol

PLEKHB2

BIRC6

Gene ID

55041

57448

Gene namepleckstrin homology domain containing B2baculoviral IAP repeat containing 6
SynonymsEVT2APOLLON|BRUCE
Cytomap('PLEKHB2')('BIRC6')

2q21.1

2p22.3

Type of geneprotein-codingprotein-coding
Descriptionpleckstrin homology domain-containing family B member 2PH domain-containing family B member 2evectin-2pleckstrin homology domain containing, family B (evectins) member 2baculoviral IAP repeat-containing protein 6BIR repeat-containing ubiquitin-conjugating enzymeRING-type E3 ubiquitin transferase BIRC6ubiquitin-conjugating BIR-domain enzyme apollon
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000439822, ENST00000234115, 
ENST00000403716, ENST00000409158, 
ENST00000409279, ENST00000409612, 
ENST00000538982, ENST00000303908, 
ENST00000404460, ENST00000438882, 
ENST00000487980, 
Fusion gene scores* DoF score4 X 2 X 4=3223 X 19 X 14=6118
# samples 529
** MAII scorelog2(5/32*10)=0.643856189774725
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(29/6118*10)=-4.39893530154327
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: PLEKHB2 [Title/Abstract] AND BIRC6 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointPLEKHB2(131897848)-BIRC6(32715108), # samples:1
Anticipated loss of major functional domain due to fusion event.PLEKHB2-BIRC6 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
PLEKHB2-BIRC6 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
PLEKHB2-BIRC6 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
PLEKHB2-BIRC6 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
PLEKHB2-BIRC6 seems lost the major protein functional domain in Tgene partner, which is a CGC due to the frame-shifted ORF.
PLEKHB2-BIRC6 seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across PLEKHB2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across BIRC6 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4PRADTCGA-CH-5792-01APLEKHB2chr2

131897848

+BIRC6chr2

32715108

+


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Fusion Gene ORF analysis for PLEKHB2-BIRC6

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
Frame-shiftENST00000439822ENST00000421745PLEKHB2chr2

131897848

+BIRC6chr2

32715108

+
In-frameENST00000234115ENST00000421745PLEKHB2chr2

131897848

+BIRC6chr2

32715108

+
In-frameENST00000403716ENST00000421745PLEKHB2chr2

131897848

+BIRC6chr2

32715108

+
In-frameENST00000409158ENST00000421745PLEKHB2chr2

131897848

+BIRC6chr2

32715108

+
In-frameENST00000409279ENST00000421745PLEKHB2chr2

131897848

+BIRC6chr2

32715108

+
In-frameENST00000409612ENST00000421745PLEKHB2chr2

131897848

+BIRC6chr2

32715108

+
In-frameENST00000538982ENST00000421745PLEKHB2chr2

131897848

+BIRC6chr2

32715108

+
intron-3CDSENST00000303908ENST00000421745PLEKHB2chr2

131897848

+BIRC6chr2

32715108

+
intron-3CDSENST00000404460ENST00000421745PLEKHB2chr2

131897848

+BIRC6chr2

32715108

+
intron-3CDSENST00000438882ENST00000421745PLEKHB2chr2

131897848

+BIRC6chr2

32715108

+
intron-3CDSENST00000487980ENST00000421745PLEKHB2chr2

131897848

+BIRC6chr2

32715108

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000409158PLEKHB2chr2131897848+ENST00000421745BIRC6chr232715108+8590111634775942415
ENST00000403716PLEKHB2chr2131897848+ENST00000421745BIRC6chr232715108+8566109234775702407
ENST00000234115PLEKHB2chr2131897848+ENST00000421745BIRC6chr232715108+846699225074702406
ENST00000538982PLEKHB2chr2131897848+ENST00000421745BIRC6chr232715108+8030556070342344
ENST00000409612PLEKHB2chr2131897848+ENST00000421745BIRC6chr232715108+8523104948775272346
ENST00000409279PLEKHB2chr2131897848+ENST00000421745BIRC6chr232715108+8801132767278052377

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000409158ENST00000421745PLEKHB2chr2131897848+BIRC6chr232715108+0.0010949110.99890506
ENST00000403716ENST00000421745PLEKHB2chr2131897848+BIRC6chr232715108+0.0010797070.9989203
ENST00000234115ENST00000421745PLEKHB2chr2131897848+BIRC6chr232715108+0.000983640.9990164
ENST00000538982ENST00000421745PLEKHB2chr2131897848+BIRC6chr232715108+0.0007673550.99923265
ENST00000409612ENST00000421745PLEKHB2chr2131897848+BIRC6chr232715108+0.000988130.9990119
ENST00000409279ENST00000421745PLEKHB2chr2131897848+BIRC6chr232715108+0.0011435510.9988564

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Fusion Genomic Features for PLEKHB2-BIRC6


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
PLEKHB2chr2131897848+BIRC6chr232715107+2.58E-050.99997413
PLEKHB2chr2131897848+BIRC6chr232715107+2.58E-050.99997413

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for PLEKHB2-BIRC6


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr2:131897848/chr2:32715108)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePLEKHB2chr2:131897848chr2:32715108ENST00000234115+782_109176222.0DomainPH
HgenePLEKHB2chr2:131897848chr2:32715108ENST00000403716+782_109177223.0DomainPH
HgenePLEKHB2chr2:131897848chr2:32715108ENST00000409158+782_109185231.0DomainPH
HgenePLEKHB2chr2:131897848chr2:32715108ENST00000409279+782_109177223.0DomainPH
HgenePLEKHB2chr2:131897848chr2:32715108ENST00000409612+782_109177223.0DomainPH
HgenePLEKHB2chr2:131897848chr2:32715108ENST00000439822+562_109133171.0DomainPH
TgeneBIRC6chr2:131897848chr2:32715108ENST0000042174541744573_474026984858.0DomainUBC core

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePLEKHB2chr2:131897848chr2:32715108ENST00000438882+172_1090179.0DomainPH
TgeneBIRC6chr2:131897848chr2:32715108ENST0000042174541741660_166826984858.0Compositional biasNote=Poly-Ala
TgeneBIRC6chr2:131897848chr2:32715108ENST00000421745417430_3626984858.0Compositional biasNote=Poly-Ala
TgeneBIRC6chr2:131897848chr2:32715108ENST000004217454174284_35826984858.0RepeatNote=BIR


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Fusion Gene Sequence for PLEKHB2-BIRC6


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>66241_66241_1_PLEKHB2-BIRC6_PLEKHB2_chr2_131897848_ENST00000234115_BIRC6_chr2_32715108_ENST00000421745_length(transcript)=8466nt_BP=992nt
CTTGGACGCCCGGTCCTTCAGTTTTTTGAGCACCTCAAGCTTCTGGCCTACAAAACGCTCCCGGCTCAGCTGGAGCTTTCTGCGCCCGGG
TCCTAGAGTCGCCCATTTCTCTAAGGCGCCTTGGCCCTATTTTTAGAGAGCGGTATTTAGAAACCAAGATTAGGGTGCTAACAATTTTTT
TTTAAATTTTTATATTTTTAAGACAGGATCTCACTTTGTAACACTTCCTTTTAGTGGAAGCGCCGACCTCCTGGGAGACCCACGCCCCCT
GCCGCCTTCCGTCCCGTTTCTCAGAAAACCACCCAGACACCCCGCCCCACCGGCCGGGGCCCGCCGCGCATGCGCGCCGAGGCGTGACGT
CAGAACGGCGGCCAGGACGCCGGACGTGCGGCAGTTGCAGGCGAGCAGGCGAGGAATCGCCGTGGCGTCTTGGTGTTCTCCACGCTGGTT
CGCAGGTGAAGAGATGGCGTTTGTGAAGAGTGGCTGGTTGCTGCGACAGAGTACTATTTTGAAGCGCTGGAAGAAGAACTGGTTTGATCT
GTGGTCGGATGGTCACCTGATCTATTATGATGACCAGACTCGGCAGAATATCGAGGATAAGGTCCACATGCCAATGGACTGCATCAACAT
CCGCACGGGGCAGGAATGTCGGGATACTCAGCCCCCGGATGGAAAGTCAAAAGACTGCATGCTCCAGATTGTTTGTCGAGATGGGAAAAC
AATTAGTCTTTGTGCAGAAAGCACAGATGATTGCTTGGCCTGGAAATTTACACTCCAAGATTCTAGGACAAACACAGCGTATGTGGGCTC
TGCAGTCATGACCGATGAGACATCCGTGGTTTCCTCACCTCCACCATACACGGCCTATGCTGCACCGGCCCCTGAGGCTTATGGCTATGG
GCCATACGGTGGTGCGTACCCGCCAGGAACTCAAGTTGTCTACGCTGCGAATGGGCAGGCGTATGCCGTGCCCTACCAGTACCCATATGC
AGCATCAATAACTAGCTTTCTCACAGTGTTAGCTTGGTATCCCAATACTTTGCTCCGGACATGGTGCCTTGTGCTTCATAGCCTAACACT
CATGACAAACATGCAGCTTAATTCTGGTTCCAGCAGTGCCATTGGAACTCAGGAGAGTACTGCTCATTTGTTGGTTTCAGATCCAAACCT
AATTCATGTATTAGTGAAATTTCTTTCTGGCACCAGTCCACATGGAACAAATCAACACAGTCCACAGGTTGGTCCTACAGCTACACAAGC
TATGCAAGAATTTCTTACTCGATTACAAGTGCATCTTTCTTCAACATGTCCTCAGATATTCAGTGAATTTTTGCTCAAGCTAATTCATAT
ACTTTCAACTGAAAGGGGTGCTTTCCAGACAGGCCAAGGACCTCTCGATGCCCAAGTGAAGCTCTTAGAATTCACTCTGGAGCAGAATTT
TGAAGTCGTTTCAGTTAGTACTATTTCTGCCGTGATAGAATCGGTTACATTTTTAGTGCACCACTATATCACTTGCTCAGACAAAGTAAT
GTCAAGAAGTGGATCAGATAGCTCCGTGGGTGCTCGAGCATGCTTTGGGGGACTCTTTGCCAATCTTATTCGTCCGGGTGATGCAAAAGC
AGTTTGTGGCGAAATGACAAGAGATCAACTCATGTTTGATTTGTTAAAACTTGTTAACATTTTAGTGCAGCTGCCTCTTTCAGGCAATAG
GGAATACAGTGCAAGAGTGTCTGTGACCACAAATACAACAGATAGTGTTTCAGATGAAGAAAAAGTCTCAGGAGGCAAAGATGGCAATGG
AAGCAGTACCAGTGTTCAAGGATCGCCTGCATATGTTGCTGACTTAGTCTTAGCCAACCAACAAATTATGAGCCAGATTTTGTCTGCTCT
GGGCCTGTGTAATAGCAGTGCCATGGCAATGATAATTGGAGCAAGTGGATTACATCTCACTAAACATGAAAACTTTCATGGTGGGTTGGA
TGCCATATCAGTTGGGGATGGATTATTTACCATACTGACAACCCTTAGTAAAAAAGCTTCTACAGTCCACATGATGCTGCAGCCAATTTT
AACATACATGGCCTGTGGATATATGGGCAGACAAGGCTCTCTTGCTACTTGCCAGTTATCTGAGCCATTATTGTGGTTCATTTTGAGAGT
ATTGGATACTAGTGATGCCTTGAAAGCATTTCATGATATGGGTGGTGTTCAGCTCATATGCAATAATATGGTTACTAGTACAAGGGCTAT
TGTGAACACTGCAAGAAGTATGGTATCAACTATTATGAAATTTCTTGACTCTGGTCCAAATAAAGCTGTTGACAGCACATTGAAAACAAG
AATACTAGCTTCTGAGCCTGACAATGCTGAAGGGATTCATAACTTTGCACCCCTCGGTACAATCACATCTAGCAGTCCTACTGCCCAACC
AGCTGAAGTGCTATTGCAGGCCACACCTCCTCACAGAAGAGCTCGCTCTGCTGCTTGGTCCTACATCTTTCTTCCAGAGGAGGCTTGGTG
TGACCTTACCATTCACCTTCCTGCAGCAGTGCTGCTTAAGGAGATACATATCCAGCCTCATCTTGCATCTCTTGCAACCTGCCCTTCCTC
AGTGTCTGTTGAAGTAAGTGCAGATGGGGTAAATATGCTACCTTTGTCCACTCCTGTTGTCACAAGTGGCCTCACCTACATAAAAATTCA
GCTTGTAAAAGCCGAAGTAGCTTCTGCTGTCTGCCTTAGACTACATCGTCCACGGGATGCCAGCACATTAGGCCTTTCACAAATTAAATT
ATTGGGGCTCACTGCTTTTGGTACCACCTCTTCTGCAACAGTTAATAATCCATTCCTTCCATCTGAAGATCAGGTATCCAAAACAAGTAT
TGGATGGTTACGGTTATTACATCATTGCCTTACTCACATAAGTGATCTAGAAGGAATGATGGCAAGTGCAGCTGCACCTACTGCTAATCT
GCTGCAGACTTGTGCGGCCTTATTGATGTCACCTTACTGTGGAATGCATTCACCCAACATCGAGGTTGTGCTTGTAAAGATAGGACTGCA
GTCTACTAGAATTGGCCTGAAGCTCATAGACATTCTCCTGAGAAATTGTGCAGCATCAGGCAGTGATCCTACAGATTTGAATAGTCCTTT
ACTTTTTGGAAGACTAAATGGACTCTCTTCTGACTCTACGATAGATATTCTTTACCAGCTTGGAACAACTCAGGATCCTGGTACAAAAGA
CAGAATTCAGGCCTTGTTAAAATGGGTTAGTGATTCTGCAAGAGTGGCTGCTATGAAGAGAAGTGGCAGGATGAACTACATGTGTCCTAA
CTCCTCAACAGTAGAGTATGGTCTTCTGATGCCATCTCCTTCTCATTTGCACTGTGTAGCAGCCATTCTGTGGCATAGTTATGAGCTGCT
TGTAGAATATGACTTACCAGCACTCCTGGACCAAGAGCTCTTTGAGTTACTTTTTAATTGGTCCATGTCTCTTCCCTGCAATATGGTTTT
GAAGAAAGCTGTTGACAGTCTACTTTGCTCAATGTGTCACGTACACCCAAACTATTTTTCTTTGCTCATGGGCTGGATGGGAATTACCCC
TCCTCCAGTGCAATGTCATCATAGACTGTCCATGACAGATGATAGCAAAAAGCAGGATCTTAGTTCATCTTTAACAGATGACTCTAAAAA
TGCACAAGCACCTCTCGCATTAACTGAATCACATTTGGCTACCCTTGCTTCCTCTTCTCAATCTCCTGAAGCTATTAAACAATTACTAGA
CTCAGGTTTGCCTTCTCTTCTTGTGAGGAGTCTGGCTAGTTTCTGCTTTAGCCACATTTCTAGCTCAGAAAGCATTGCCCAGTCAATAGA
TATTTCCCAGGACAAACTCAGGCGCCATCATGTCCCACAACAATGTAATAAGATGCCTATCACAGCCGACCTAGTTGCTCCTATTCTTAG
GTTTTTGACAGAAGTTGGCAATAGCCATATTATGAAAGATTGGCTTGGTGGTTCTGAAGTCAATCCACTATGGACAGCACTTCTGTTTTT
ATTGTGTCACTCTGGGTCCACTTCTGGAAGCCATAATTTAGGTGCACAACAGACCAGTGCAAGATCAGCTTCTCTTTCTTCAGCTGCTAC
AACAGGACTGACTACTCAACAGCGCACAGCAATTGAGAATGCAACTGTTGCGTTCTTTCTACAGTGCATTTCATGCCATCCTAATAATCA
AAAGCTGATGGCACAGGTTCTTTGTGAACTATTTCAGACATCTCCTCAAAGAGGGAACCTTCCAACATCTGGGAACATTTCAGGGTTTAT
ACGAAGATTATTTTTACAGTTGATGCTGGAAGATGAGAAAGTGACAATGTTTCTTCAGTCTCCATGTCCACTGTACAAAGGTAGAATTAA
TGCTACTAGCCACGTCATCCAGCATCCAATGTATGGAGCAGGCCACAAATTCCGTACTCTTCATTTGCCAGTCTCAACAACATTATCAGA
TGTTCTTGACAGAGTGTCAGATACTCCAAGTATCACAGCTAAATTAATTAGTGAACAAAAAGATGACAAAGAAAAGAAAAACCATGAAGA
GAAAGAAAAAGTTAAAGCGGAAAATGGATTTCAAGACAATTACAGTGTTGTTGTTGCCTCTGGGCTGAAGTCTCAATCTAAACGTGCTGT
GTCAGCTACACCACCTCGCCCACCATCCAGGAGGGGGAGGACAATACCTGATAAAATAGGAAGTACTTCAGGAGCAGAGGCTGCCAACAA
AATAATTACTGTCCCAGTGTTTCACCTGTTTCACAAACTCTTGGCAGGCCAGCCATTGCCAGCTGAAATGACACTTGCCCAGCTTTTAAC
TCTCCTATATGACCGAAAACTTCCTCAGGGTTACCGCTCAATAGATCTGACTGTTAAATTGGGATCAAGAGTTATAACAGACCCCAGTCT
ATCAAAAACAGATTCTTATAAAAGACTACACCCTGAAAAAGATCATGGAGACTTACTTGCTAGCTGTCCAGAAGATGAGGCTCTCACTCC
AGGTGATGAATGCATGGATGGGATACTGGATGAATCTTTGCTTGAAACCTGTCCAATTCAGTCACCATTACAAGTTTTTGCAGGAATGGG
TGGACTGGCTCTTATTGCTGAAAGACTACCCATGCTATATCCAGAAGTAATTCAACAGGTGAGTGCTCCAGTTGTAACATCTACCACTCA
GGAAAAGCCGAAGGATAGCGATCAGTTTGAATGGGTGACCATTGAACAGTCAGGGGAGTTAGTTTATGAAGCACCAGAAACTGTTGCGGC
TGAACCTCCACCTATCAAGTCAGCAGTACAGACCATGTCTCCCATACCTGCCCATTCTTTGGCTGCTTTTGGATTATTTCTTCGTCTTCC
GGGCTATGCGGAAGTGCTACTGAAAGAGAGAAAACATGCCCAGTGCCTTCTTCGATTGGTATTGGGAGTGACAGATGATGGAGAAGGAAG
TCATATTCTTCAATCTCCATCAGCCAATGTGCTTCCAACCCTTCCTTTCCACGTCCTTCGTAGCTTGTTTAGCACTACACCTTTGACAAC
TGATGATGGTGTACTTCTAAGGCGGATGGCATTGGAAATTGGAGCCTTACACCTCATTCTTGTCTGTCTCTCTGCTTTGAGCCACCATTC
CCCACGAGTTCCAAACTCTAGCGTGAATCAAACTGAGCCACAGGTGTCAAGCTCTCATAACCCTACATCAACAGAAGAACAACAGTTATA
TTGGGCCAAAGGGACTGGCTTTGGAACAGGCTCTACAGCTTCTGGGTGGGATGTGGAACAAGCCTTAACTAAGCAAAGGCTGGAAGAGGA
ACATGTTACCTGCCTTCTGCAGGTTCTTGCCAGTTACATAAATCCCGTCAGTAGTGCGGTAAATGGAGAAGCTCAGTCATCTCATGAGAC
TAGAGGGCAGAACAGTAATGCCCTTCCTTCTGTACTTCTCGAGCTTCTCAGTCAGTCCTGCCTCATCCCAGCCATGTCATCTTATCTACG
AAATGATTCAGTTCTGGACATGGCAAGACATGTGCCACTCTATCGGGCACTGCTGGAATTGCTTCGGGCCATTGCTTCTTGTGCTGCCAT
GGTGCCCCTATTGTTGCCCCTTTCTACAGAGAACGGTGAAGAGGAAGAAGAACAGTCAGAATGTCAAACTTCTGTTGGTACATTGTTAGC
CAAAATGAAGACCTGTGTTGATACCTATACCAACCGTTTAAGATCTAAAAGGGAAAATGTTAAAACAGGAGTAAAACCAGATGCGTCTGA
TCAAGAACCAGAAGGACTTACTCTTTTGGTACCAGACATCCAAAAGACTGCTGAGATAGTTTATGCAGCCACCACCAGTTTGCGGCAAGC
AAATCAGGAAAAAAAACTGGGTGAATACTCCAAGAAGGCGGCTATGAAACCCAAACCTTTGTCAGTATTAAAGTCACTTGAAGAAAAATA
TGTGGCTGTTATGAAGAAATTACAGTTTGATACGTTTGAAATGGTTTCTGAAGATGAAGATGGGAAATTGGGATTTAAAGTAAATTACCA
CTACATGTCTCAGGTGAAAAATGCTAATGATGCGAACAGTGCTGCCAGAGCTCGCCGCCTTGCCCAGGAAGCTGTGACGCTTTCAACCTC
ACTGCCTCTGTCTTCATCCTCTAGTGTGTTTGTACGCTGTGATGAGGAGCGACTTGATATCATGAAGGTTCTAATAACTGGTCCAGCGGA
CACCCCTTATGCAAATGGCTGCTTTGAGTTTGATGTGTATTTTCCTCAAGATTATCCCAGTTCACCCCCTCTTGTGAATCTAGAGACAAC
TGGTGGTCATAGCGTGCGATTCAATCCAAACCTTTATAATGATGGCAAGGTTTGTTTAAGCATCTTAAACACGTGGCATGGAAGACCAGA
AGAGAAGTGGAATCCTCAGACCTCAAGCTTTTTGCAAGTGTTGGTGTCTGTCCAGTCCCTTATATTAGTAGCTGAGCCTTATTTTAATGA
ACCGGGATATGAACGGTCTAGAGGCACTCCCAGTGGCACACAGAGTTCTCGAGAATATGATGGAAACATTCGACAAGCAACAGTTAAGTG
GGCAATGCTAGAACAAATCAGAAACCCTTCACCATGTTTTAAAGAGGTAATACACAAACATTTTTACTTGAAAAGAGTTGAGATAATGGC
CCAATGTGAGGAGTGGATTGCGGATATCCAGCAGTACAGCAGTGATAAGCGGGTAGGCAGGACTATGTCTCACCATGCAGCAGCTCTCAA
GCGTCACACTGCTCAGCTCCGCGAAGAGTTGCTGAAACTTCCCTGCCCTGAAGGCTTGGATCCTGACACTGACGATGCCCCAGAGGTGTG
CAGAGCCACAACAGGTGCTGAGGAGACTCTAATGCATGATCAGGTTAAACCCAGCAGCAGCAAAGAACTCCCCAGTGACTTCCAGTTATG
AGCTGCATTGATGTGGACTTCATAGACACAAAGGCTTCGAAGCACAAGCCAAATATGTCAATATTTGTATGTAAGAAACTAATTATGTAA
TAGGTAATGAAACTGAAACTATACTATGCCCTTAAGGAGATCCAGTTTAATTCAAGGTGATCTTTTATTTACCTGTACAGGAGTGTAAAC
TTTTTTGTGCTTTTATTTTTCAATTGTGAGAACCACTGATTGGTATGTTCAACAAATTTGTGTATACAAAGAAATGGATAAATCACTGCT
ATATAAGGGAAACTACCTTAGGAAAGAATGTTTACTGAATGTTTATTTTATTTTATTTTTTTTTTACTATAGAGTGAGGGGTTGTTAACA
AAGAATATATATTGGTCATTCTTACAACTACTATTTAAAGTCAGCAACTTTTCACTGAATTTGATAGATTTTATGTTTGGCCATATCTTC
ATGCTCACATTTGATTTCTGAAGACCTCCTACATACACTTCAATAAAAGTTAAATGGACATACTCCCTCTTTTTTGATTTACTGGTACAT
TTTTAAAATAATAAATCTGCCATAAAATGCATTATATCTGGAGACTTGCACTTGTATGGATGAATTTATTACATTCAACATATTTAATTT
TATGCCTTCTAATTCTAAGATGCAGAAAAAAATAAATGAACATGATTTTATTCTATGCCAACATTTGGGCCTCTGAATGTATCTGTTATT
TGAATTTAAGTATTTGAAAAGGAATGGTCAATTTGAAAGTCATTCTAAACTGATTTTTTTTTTCTAAAGGGCTCCTTTTTTCCTGGACTA
TGTGGTTTTATGACTAAAGTCACATGTATGTATTAAACATTGAGGCTCTGTAGAGGAGAGAGGATGTACCTCTCTGGTGCTGTTACAGTA
CATTCTGTACCTGCCATACAGGCTCATTTTCATGCAAATTCTTCCTAGAGCCAAATAAATAAAGACTTAGGTGAATTAGTATGTCTTGTT

>66241_66241_1_PLEKHB2-BIRC6_PLEKHB2_chr2_131897848_ENST00000234115_BIRC6_chr2_32715108_ENST00000421745_length(amino acids)=2406AA_BP=247
MGDPRPLPPSVPFLRKPPRHPAPPAGARRACAPRRDVRTAARTPDVRQLQASRRGIAVASWCSPRWFAGEEMAFVKSGWLLRQSTILKRW
KKNWFDLWSDGHLIYYDDQTRQNIEDKVHMPMDCINIRTGQECRDTQPPDGKSKDCMLQIVCRDGKTISLCAESTDDCLAWKFTLQDSRT
NTAYVGSAVMTDETSVVSSPPPYTAYAAPAPEAYGYGPYGGAYPPGTQVVYAANGQAYAVPYQYPYAASITSFLTVLAWYPNTLLRTWCL
VLHSLTLMTNMQLNSGSSSAIGTQESTAHLLVSDPNLIHVLVKFLSGTSPHGTNQHSPQVGPTATQAMQEFLTRLQVHLSSTCPQIFSEF
LLKLIHILSTERGAFQTGQGPLDAQVKLLEFTLEQNFEVVSVSTISAVIESVTFLVHHYITCSDKVMSRSGSDSSVGARACFGGLFANLI
RPGDAKAVCGEMTRDQLMFDLLKLVNILVQLPLSGNREYSARVSVTTNTTDSVSDEEKVSGGKDGNGSSTSVQGSPAYVADLVLANQQIM
SQILSALGLCNSSAMAMIIGASGLHLTKHENFHGGLDAISVGDGLFTILTTLSKKASTVHMMLQPILTYMACGYMGRQGSLATCQLSEPL
LWFILRVLDTSDALKAFHDMGGVQLICNNMVTSTRAIVNTARSMVSTIMKFLDSGPNKAVDSTLKTRILASEPDNAEGIHNFAPLGTITS
SSPTAQPAEVLLQATPPHRRARSAAWSYIFLPEEAWCDLTIHLPAAVLLKEIHIQPHLASLATCPSSVSVEVSADGVNMLPLSTPVVTSG
LTYIKIQLVKAEVASAVCLRLHRPRDASTLGLSQIKLLGLTAFGTTSSATVNNPFLPSEDQVSKTSIGWLRLLHHCLTHISDLEGMMASA
AAPTANLLQTCAALLMSPYCGMHSPNIEVVLVKIGLQSTRIGLKLIDILLRNCAASGSDPTDLNSPLLFGRLNGLSSDSTIDILYQLGTT
QDPGTKDRIQALLKWVSDSARVAAMKRSGRMNYMCPNSSTVEYGLLMPSPSHLHCVAAILWHSYELLVEYDLPALLDQELFELLFNWSMS
LPCNMVLKKAVDSLLCSMCHVHPNYFSLLMGWMGITPPPVQCHHRLSMTDDSKKQDLSSSLTDDSKNAQAPLALTESHLATLASSSQSPE
AIKQLLDSGLPSLLVRSLASFCFSHISSSESIAQSIDISQDKLRRHHVPQQCNKMPITADLVAPILRFLTEVGNSHIMKDWLGGSEVNPL
WTALLFLLCHSGSTSGSHNLGAQQTSARSASLSSAATTGLTTQQRTAIENATVAFFLQCISCHPNNQKLMAQVLCELFQTSPQRGNLPTS
GNISGFIRRLFLQLMLEDEKVTMFLQSPCPLYKGRINATSHVIQHPMYGAGHKFRTLHLPVSTTLSDVLDRVSDTPSITAKLISEQKDDK
EKKNHEEKEKVKAENGFQDNYSVVVASGLKSQSKRAVSATPPRPPSRRGRTIPDKIGSTSGAEAANKIITVPVFHLFHKLLAGQPLPAEM
TLAQLLTLLYDRKLPQGYRSIDLTVKLGSRVITDPSLSKTDSYKRLHPEKDHGDLLASCPEDEALTPGDECMDGILDESLLETCPIQSPL
QVFAGMGGLALIAERLPMLYPEVIQQVSAPVVTSTTQEKPKDSDQFEWVTIEQSGELVYEAPETVAAEPPPIKSAVQTMSPIPAHSLAAF
GLFLRLPGYAEVLLKERKHAQCLLRLVLGVTDDGEGSHILQSPSANVLPTLPFHVLRSLFSTTPLTTDDGVLLRRMALEIGALHLILVCL
SALSHHSPRVPNSSVNQTEPQVSSSHNPTSTEEQQLYWAKGTGFGTGSTASGWDVEQALTKQRLEEEHVTCLLQVLASYINPVSSAVNGE
AQSSHETRGQNSNALPSVLLELLSQSCLIPAMSSYLRNDSVLDMARHVPLYRALLELLRAIASCAAMVPLLLPLSTENGEEEEEQSECQT
SVGTLLAKMKTCVDTYTNRLRSKRENVKTGVKPDASDQEPEGLTLLVPDIQKTAEIVYAATTSLRQANQEKKLGEYSKKAAMKPKPLSVL
KSLEEKYVAVMKKLQFDTFEMVSEDEDGKLGFKVNYHYMSQVKNANDANSAARARRLAQEAVTLSTSLPLSSSSSVFVRCDEERLDIMKV
LITGPADTPYANGCFEFDVYFPQDYPSSPPLVNLETTGGHSVRFNPNLYNDGKVCLSILNTWHGRPEEKWNPQTSSFLQVLVSVQSLILV
AEPYFNEPGYERSRGTPSGTQSSREYDGNIRQATVKWAMLEQIRNPSPCFKEVIHKHFYLKRVEIMAQCEEWIADIQQYSSDKRVGRTMS

--------------------------------------------------------------
>66241_66241_2_PLEKHB2-BIRC6_PLEKHB2_chr2_131897848_ENST00000403716_BIRC6_chr2_32715108_ENST00000421745_length(transcript)=8566nt_BP=1092nt
ATACTTTAGGTTATAACTTAATGCAATGTACTTTATATTGCTGCTCAAATTGTCCCAGGCGCGGCCCCCGGAAGCTCTCTGGGTAGATCC
CTGCGCCCTTGGACGCCCGGTCCTTCAGTTTTTTGAGCACCTCAAGCTTCTGGCCTACAAAACGCTCCCGGCTCAGCTGGAGCTTTCTGC
GCCCGGGTCCTAGAGTCGCCCATTTCTCTAAGGCGCCTTGGCCCTATTTTTAGAGAGCGGTATTTAGAAACCAAGATTAGGGTGCTAACA
ATTTTTTTTTAAATTTTTATATTTTTAAGACAGGATCTCACTTTGTAACACTTCCTTTTAGTGGAAGCGCCGACCTCCTGGGAGACCCAC
GCCCCCTGCCGCCTTCCGTCCCGTTTCTCAGAAAACCACCCAGACACCCCGCCCCACCGGCCGGGGCCCGCCGCGCATGCGCGCCGAGGC
GTGACGTCAGAACGGCGGCCAGGACGCCGGACGTGCGGCAGTTGCAGGCGAGCAGGCGAGGAATCGCCGTGGCGTCTTGGTGTTCTCCAC
GCTGGTTCGCAGGTGAAGAGATGGCGTTTGTGAAGAGTGGCTGGTTGCTGCGACAGAGTACTATTTTGAAGCGCTGGAAGAAGAACTGGT
TTGATCTGTGGTCGGATGGTCACCTGATCTATTATGATGACCAGACTCGGCAGAATATCGAGGATAAGGTCCACATGCCAATGGACTGCA
TCAACATCCGCACGGGGCAGGAATGTCGGGATACTCAGCCCCCGGATGGAAAGTCAAAAGACTGCATGCTCCAGATTGTTTGTCGAGATG
GGAAAACAATTAGTCTTTGTGCAGAAAGCACAGATGATTGCTTGGCCTGGAAATTTACACTCCAAGATTCTAGGACAAACACAGCGTATG
TGGGCTCTGCAGTCATGACCGATGAGACATCCGTGGTTTCCTCACCTCCACCATACACGGCCTATGCTGCACCGGCCCCTGAGCAGGCTT
ATGGCTATGGGCCATACGGTGGTGCGTACCCGCCAGGAACTCAAGTTGTCTACGCTGCGAATGGGCAGGCGTATGCCGTGCCCTACCAGT
ACCCATATGCAGCATCAATAACTAGCTTTCTCACAGTGTTAGCTTGGTATCCCAATACTTTGCTCCGGACATGGTGCCTTGTGCTTCATA
GCCTAACACTCATGACAAACATGCAGCTTAATTCTGGTTCCAGCAGTGCCATTGGAACTCAGGAGAGTACTGCTCATTTGTTGGTTTCAG
ATCCAAACCTAATTCATGTATTAGTGAAATTTCTTTCTGGCACCAGTCCACATGGAACAAATCAACACAGTCCACAGGTTGGTCCTACAG
CTACACAAGCTATGCAAGAATTTCTTACTCGATTACAAGTGCATCTTTCTTCAACATGTCCTCAGATATTCAGTGAATTTTTGCTCAAGC
TAATTCATATACTTTCAACTGAAAGGGGTGCTTTCCAGACAGGCCAAGGACCTCTCGATGCCCAAGTGAAGCTCTTAGAATTCACTCTGG
AGCAGAATTTTGAAGTCGTTTCAGTTAGTACTATTTCTGCCGTGATAGAATCGGTTACATTTTTAGTGCACCACTATATCACTTGCTCAG
ACAAAGTAATGTCAAGAAGTGGATCAGATAGCTCCGTGGGTGCTCGAGCATGCTTTGGGGGACTCTTTGCCAATCTTATTCGTCCGGGTG
ATGCAAAAGCAGTTTGTGGCGAAATGACAAGAGATCAACTCATGTTTGATTTGTTAAAACTTGTTAACATTTTAGTGCAGCTGCCTCTTT
CAGGCAATAGGGAATACAGTGCAAGAGTGTCTGTGACCACAAATACAACAGATAGTGTTTCAGATGAAGAAAAAGTCTCAGGAGGCAAAG
ATGGCAATGGAAGCAGTACCAGTGTTCAAGGATCGCCTGCATATGTTGCTGACTTAGTCTTAGCCAACCAACAAATTATGAGCCAGATTT
TGTCTGCTCTGGGCCTGTGTAATAGCAGTGCCATGGCAATGATAATTGGAGCAAGTGGATTACATCTCACTAAACATGAAAACTTTCATG
GTGGGTTGGATGCCATATCAGTTGGGGATGGATTATTTACCATACTGACAACCCTTAGTAAAAAAGCTTCTACAGTCCACATGATGCTGC
AGCCAATTTTAACATACATGGCCTGTGGATATATGGGCAGACAAGGCTCTCTTGCTACTTGCCAGTTATCTGAGCCATTATTGTGGTTCA
TTTTGAGAGTATTGGATACTAGTGATGCCTTGAAAGCATTTCATGATATGGGTGGTGTTCAGCTCATATGCAATAATATGGTTACTAGTA
CAAGGGCTATTGTGAACACTGCAAGAAGTATGGTATCAACTATTATGAAATTTCTTGACTCTGGTCCAAATAAAGCTGTTGACAGCACAT
TGAAAACAAGAATACTAGCTTCTGAGCCTGACAATGCTGAAGGGATTCATAACTTTGCACCCCTCGGTACAATCACATCTAGCAGTCCTA
CTGCCCAACCAGCTGAAGTGCTATTGCAGGCCACACCTCCTCACAGAAGAGCTCGCTCTGCTGCTTGGTCCTACATCTTTCTTCCAGAGG
AGGCTTGGTGTGACCTTACCATTCACCTTCCTGCAGCAGTGCTGCTTAAGGAGATACATATCCAGCCTCATCTTGCATCTCTTGCAACCT
GCCCTTCCTCAGTGTCTGTTGAAGTAAGTGCAGATGGGGTAAATATGCTACCTTTGTCCACTCCTGTTGTCACAAGTGGCCTCACCTACA
TAAAAATTCAGCTTGTAAAAGCCGAAGTAGCTTCTGCTGTCTGCCTTAGACTACATCGTCCACGGGATGCCAGCACATTAGGCCTTTCAC
AAATTAAATTATTGGGGCTCACTGCTTTTGGTACCACCTCTTCTGCAACAGTTAATAATCCATTCCTTCCATCTGAAGATCAGGTATCCA
AAACAAGTATTGGATGGTTACGGTTATTACATCATTGCCTTACTCACATAAGTGATCTAGAAGGAATGATGGCAAGTGCAGCTGCACCTA
CTGCTAATCTGCTGCAGACTTGTGCGGCCTTATTGATGTCACCTTACTGTGGAATGCATTCACCCAACATCGAGGTTGTGCTTGTAAAGA
TAGGACTGCAGTCTACTAGAATTGGCCTGAAGCTCATAGACATTCTCCTGAGAAATTGTGCAGCATCAGGCAGTGATCCTACAGATTTGA
ATAGTCCTTTACTTTTTGGAAGACTAAATGGACTCTCTTCTGACTCTACGATAGATATTCTTTACCAGCTTGGAACAACTCAGGATCCTG
GTACAAAAGACAGAATTCAGGCCTTGTTAAAATGGGTTAGTGATTCTGCAAGAGTGGCTGCTATGAAGAGAAGTGGCAGGATGAACTACA
TGTGTCCTAACTCCTCAACAGTAGAGTATGGTCTTCTGATGCCATCTCCTTCTCATTTGCACTGTGTAGCAGCCATTCTGTGGCATAGTT
ATGAGCTGCTTGTAGAATATGACTTACCAGCACTCCTGGACCAAGAGCTCTTTGAGTTACTTTTTAATTGGTCCATGTCTCTTCCCTGCA
ATATGGTTTTGAAGAAAGCTGTTGACAGTCTACTTTGCTCAATGTGTCACGTACACCCAAACTATTTTTCTTTGCTCATGGGCTGGATGG
GAATTACCCCTCCTCCAGTGCAATGTCATCATAGACTGTCCATGACAGATGATAGCAAAAAGCAGGATCTTAGTTCATCTTTAACAGATG
ACTCTAAAAATGCACAAGCACCTCTCGCATTAACTGAATCACATTTGGCTACCCTTGCTTCCTCTTCTCAATCTCCTGAAGCTATTAAAC
AATTACTAGACTCAGGTTTGCCTTCTCTTCTTGTGAGGAGTCTGGCTAGTTTCTGCTTTAGCCACATTTCTAGCTCAGAAAGCATTGCCC
AGTCAATAGATATTTCCCAGGACAAACTCAGGCGCCATCATGTCCCACAACAATGTAATAAGATGCCTATCACAGCCGACCTAGTTGCTC
CTATTCTTAGGTTTTTGACAGAAGTTGGCAATAGCCATATTATGAAAGATTGGCTTGGTGGTTCTGAAGTCAATCCACTATGGACAGCAC
TTCTGTTTTTATTGTGTCACTCTGGGTCCACTTCTGGAAGCCATAATTTAGGTGCACAACAGACCAGTGCAAGATCAGCTTCTCTTTCTT
CAGCTGCTACAACAGGACTGACTACTCAACAGCGCACAGCAATTGAGAATGCAACTGTTGCGTTCTTTCTACAGTGCATTTCATGCCATC
CTAATAATCAAAAGCTGATGGCACAGGTTCTTTGTGAACTATTTCAGACATCTCCTCAAAGAGGGAACCTTCCAACATCTGGGAACATTT
CAGGGTTTATACGAAGATTATTTTTACAGTTGATGCTGGAAGATGAGAAAGTGACAATGTTTCTTCAGTCTCCATGTCCACTGTACAAAG
GTAGAATTAATGCTACTAGCCACGTCATCCAGCATCCAATGTATGGAGCAGGCCACAAATTCCGTACTCTTCATTTGCCAGTCTCAACAA
CATTATCAGATGTTCTTGACAGAGTGTCAGATACTCCAAGTATCACAGCTAAATTAATTAGTGAACAAAAAGATGACAAAGAAAAGAAAA
ACCATGAAGAGAAAGAAAAAGTTAAAGCGGAAAATGGATTTCAAGACAATTACAGTGTTGTTGTTGCCTCTGGGCTGAAGTCTCAATCTA
AACGTGCTGTGTCAGCTACACCACCTCGCCCACCATCCAGGAGGGGGAGGACAATACCTGATAAAATAGGAAGTACTTCAGGAGCAGAGG
CTGCCAACAAAATAATTACTGTCCCAGTGTTTCACCTGTTTCACAAACTCTTGGCAGGCCAGCCATTGCCAGCTGAAATGACACTTGCCC
AGCTTTTAACTCTCCTATATGACCGAAAACTTCCTCAGGGTTACCGCTCAATAGATCTGACTGTTAAATTGGGATCAAGAGTTATAACAG
ACCCCAGTCTATCAAAAACAGATTCTTATAAAAGACTACACCCTGAAAAAGATCATGGAGACTTACTTGCTAGCTGTCCAGAAGATGAGG
CTCTCACTCCAGGTGATGAATGCATGGATGGGATACTGGATGAATCTTTGCTTGAAACCTGTCCAATTCAGTCACCATTACAAGTTTTTG
CAGGAATGGGTGGACTGGCTCTTATTGCTGAAAGACTACCCATGCTATATCCAGAAGTAATTCAACAGGTGAGTGCTCCAGTTGTAACAT
CTACCACTCAGGAAAAGCCGAAGGATAGCGATCAGTTTGAATGGGTGACCATTGAACAGTCAGGGGAGTTAGTTTATGAAGCACCAGAAA
CTGTTGCGGCTGAACCTCCACCTATCAAGTCAGCAGTACAGACCATGTCTCCCATACCTGCCCATTCTTTGGCTGCTTTTGGATTATTTC
TTCGTCTTCCGGGCTATGCGGAAGTGCTACTGAAAGAGAGAAAACATGCCCAGTGCCTTCTTCGATTGGTATTGGGAGTGACAGATGATG
GAGAAGGAAGTCATATTCTTCAATCTCCATCAGCCAATGTGCTTCCAACCCTTCCTTTCCACGTCCTTCGTAGCTTGTTTAGCACTACAC
CTTTGACAACTGATGATGGTGTACTTCTAAGGCGGATGGCATTGGAAATTGGAGCCTTACACCTCATTCTTGTCTGTCTCTCTGCTTTGA
GCCACCATTCCCCACGAGTTCCAAACTCTAGCGTGAATCAAACTGAGCCACAGGTGTCAAGCTCTCATAACCCTACATCAACAGAAGAAC
AACAGTTATATTGGGCCAAAGGGACTGGCTTTGGAACAGGCTCTACAGCTTCTGGGTGGGATGTGGAACAAGCCTTAACTAAGCAAAGGC
TGGAAGAGGAACATGTTACCTGCCTTCTGCAGGTTCTTGCCAGTTACATAAATCCCGTCAGTAGTGCGGTAAATGGAGAAGCTCAGTCAT
CTCATGAGACTAGAGGGCAGAACAGTAATGCCCTTCCTTCTGTACTTCTCGAGCTTCTCAGTCAGTCCTGCCTCATCCCAGCCATGTCAT
CTTATCTACGAAATGATTCAGTTCTGGACATGGCAAGACATGTGCCACTCTATCGGGCACTGCTGGAATTGCTTCGGGCCATTGCTTCTT
GTGCTGCCATGGTGCCCCTATTGTTGCCCCTTTCTACAGAGAACGGTGAAGAGGAAGAAGAACAGTCAGAATGTCAAACTTCTGTTGGTA
CATTGTTAGCCAAAATGAAGACCTGTGTTGATACCTATACCAACCGTTTAAGATCTAAAAGGGAAAATGTTAAAACAGGAGTAAAACCAG
ATGCGTCTGATCAAGAACCAGAAGGACTTACTCTTTTGGTACCAGACATCCAAAAGACTGCTGAGATAGTTTATGCAGCCACCACCAGTT
TGCGGCAAGCAAATCAGGAAAAAAAACTGGGTGAATACTCCAAGAAGGCGGCTATGAAACCCAAACCTTTGTCAGTATTAAAGTCACTTG
AAGAAAAATATGTGGCTGTTATGAAGAAATTACAGTTTGATACGTTTGAAATGGTTTCTGAAGATGAAGATGGGAAATTGGGATTTAAAG
TAAATTACCACTACATGTCTCAGGTGAAAAATGCTAATGATGCGAACAGTGCTGCCAGAGCTCGCCGCCTTGCCCAGGAAGCTGTGACGC
TTTCAACCTCACTGCCTCTGTCTTCATCCTCTAGTGTGTTTGTACGCTGTGATGAGGAGCGACTTGATATCATGAAGGTTCTAATAACTG
GTCCAGCGGACACCCCTTATGCAAATGGCTGCTTTGAGTTTGATGTGTATTTTCCTCAAGATTATCCCAGTTCACCCCCTCTTGTGAATC
TAGAGACAACTGGTGGTCATAGCGTGCGATTCAATCCAAACCTTTATAATGATGGCAAGGTTTGTTTAAGCATCTTAAACACGTGGCATG
GAAGACCAGAAGAGAAGTGGAATCCTCAGACCTCAAGCTTTTTGCAAGTGTTGGTGTCTGTCCAGTCCCTTATATTAGTAGCTGAGCCTT
ATTTTAATGAACCGGGATATGAACGGTCTAGAGGCACTCCCAGTGGCACACAGAGTTCTCGAGAATATGATGGAAACATTCGACAAGCAA
CAGTTAAGTGGGCAATGCTAGAACAAATCAGAAACCCTTCACCATGTTTTAAAGAGGTAATACACAAACATTTTTACTTGAAAAGAGTTG
AGATAATGGCCCAATGTGAGGAGTGGATTGCGGATATCCAGCAGTACAGCAGTGATAAGCGGGTAGGCAGGACTATGTCTCACCATGCAG
CAGCTCTCAAGCGTCACACTGCTCAGCTCCGCGAAGAGTTGCTGAAACTTCCCTGCCCTGAAGGCTTGGATCCTGACACTGACGATGCCC
CAGAGGTGTGCAGAGCCACAACAGGTGCTGAGGAGACTCTAATGCATGATCAGGTTAAACCCAGCAGCAGCAAAGAACTCCCCAGTGACT
TCCAGTTATGAGCTGCATTGATGTGGACTTCATAGACACAAAGGCTTCGAAGCACAAGCCAAATATGTCAATATTTGTATGTAAGAAACT
AATTATGTAATAGGTAATGAAACTGAAACTATACTATGCCCTTAAGGAGATCCAGTTTAATTCAAGGTGATCTTTTATTTACCTGTACAG
GAGTGTAAACTTTTTTGTGCTTTTATTTTTCAATTGTGAGAACCACTGATTGGTATGTTCAACAAATTTGTGTATACAAAGAAATGGATA
AATCACTGCTATATAAGGGAAACTACCTTAGGAAAGAATGTTTACTGAATGTTTATTTTATTTTATTTTTTTTTTACTATAGAGTGAGGG
GTTGTTAACAAAGAATATATATTGGTCATTCTTACAACTACTATTTAAAGTCAGCAACTTTTCACTGAATTTGATAGATTTTATGTTTGG
CCATATCTTCATGCTCACATTTGATTTCTGAAGACCTCCTACATACACTTCAATAAAAGTTAAATGGACATACTCCCTCTTTTTTGATTT
ACTGGTACATTTTTAAAATAATAAATCTGCCATAAAATGCATTATATCTGGAGACTTGCACTTGTATGGATGAATTTATTACATTCAACA
TATTTAATTTTATGCCTTCTAATTCTAAGATGCAGAAAAAAATAAATGAACATGATTTTATTCTATGCCAACATTTGGGCCTCTGAATGT
ATCTGTTATTTGAATTTAAGTATTTGAAAAGGAATGGTCAATTTGAAAGTCATTCTAAACTGATTTTTTTTTTCTAAAGGGCTCCTTTTT
TCCTGGACTATGTGGTTTTATGACTAAAGTCACATGTATGTATTAAACATTGAGGCTCTGTAGAGGAGAGAGGATGTACCTCTCTGGTGC
TGTTACAGTACATTCTGTACCTGCCATACAGGCTCATTTTCATGCAAATTCTTCCTAGAGCCAAATAAATAAAGACTTAGGTGAATTAGT

>66241_66241_2_PLEKHB2-BIRC6_PLEKHB2_chr2_131897848_ENST00000403716_BIRC6_chr2_32715108_ENST00000421745_length(amino acids)=2407AA_BP=248
MGDPRPLPPSVPFLRKPPRHPAPPAGARRACAPRRDVRTAARTPDVRQLQASRRGIAVASWCSPRWFAGEEMAFVKSGWLLRQSTILKRW
KKNWFDLWSDGHLIYYDDQTRQNIEDKVHMPMDCINIRTGQECRDTQPPDGKSKDCMLQIVCRDGKTISLCAESTDDCLAWKFTLQDSRT
NTAYVGSAVMTDETSVVSSPPPYTAYAAPAPEQAYGYGPYGGAYPPGTQVVYAANGQAYAVPYQYPYAASITSFLTVLAWYPNTLLRTWC
LVLHSLTLMTNMQLNSGSSSAIGTQESTAHLLVSDPNLIHVLVKFLSGTSPHGTNQHSPQVGPTATQAMQEFLTRLQVHLSSTCPQIFSE
FLLKLIHILSTERGAFQTGQGPLDAQVKLLEFTLEQNFEVVSVSTISAVIESVTFLVHHYITCSDKVMSRSGSDSSVGARACFGGLFANL
IRPGDAKAVCGEMTRDQLMFDLLKLVNILVQLPLSGNREYSARVSVTTNTTDSVSDEEKVSGGKDGNGSSTSVQGSPAYVADLVLANQQI
MSQILSALGLCNSSAMAMIIGASGLHLTKHENFHGGLDAISVGDGLFTILTTLSKKASTVHMMLQPILTYMACGYMGRQGSLATCQLSEP
LLWFILRVLDTSDALKAFHDMGGVQLICNNMVTSTRAIVNTARSMVSTIMKFLDSGPNKAVDSTLKTRILASEPDNAEGIHNFAPLGTIT
SSSPTAQPAEVLLQATPPHRRARSAAWSYIFLPEEAWCDLTIHLPAAVLLKEIHIQPHLASLATCPSSVSVEVSADGVNMLPLSTPVVTS
GLTYIKIQLVKAEVASAVCLRLHRPRDASTLGLSQIKLLGLTAFGTTSSATVNNPFLPSEDQVSKTSIGWLRLLHHCLTHISDLEGMMAS
AAAPTANLLQTCAALLMSPYCGMHSPNIEVVLVKIGLQSTRIGLKLIDILLRNCAASGSDPTDLNSPLLFGRLNGLSSDSTIDILYQLGT
TQDPGTKDRIQALLKWVSDSARVAAMKRSGRMNYMCPNSSTVEYGLLMPSPSHLHCVAAILWHSYELLVEYDLPALLDQELFELLFNWSM
SLPCNMVLKKAVDSLLCSMCHVHPNYFSLLMGWMGITPPPVQCHHRLSMTDDSKKQDLSSSLTDDSKNAQAPLALTESHLATLASSSQSP
EAIKQLLDSGLPSLLVRSLASFCFSHISSSESIAQSIDISQDKLRRHHVPQQCNKMPITADLVAPILRFLTEVGNSHIMKDWLGGSEVNP
LWTALLFLLCHSGSTSGSHNLGAQQTSARSASLSSAATTGLTTQQRTAIENATVAFFLQCISCHPNNQKLMAQVLCELFQTSPQRGNLPT
SGNISGFIRRLFLQLMLEDEKVTMFLQSPCPLYKGRINATSHVIQHPMYGAGHKFRTLHLPVSTTLSDVLDRVSDTPSITAKLISEQKDD
KEKKNHEEKEKVKAENGFQDNYSVVVASGLKSQSKRAVSATPPRPPSRRGRTIPDKIGSTSGAEAANKIITVPVFHLFHKLLAGQPLPAE
MTLAQLLTLLYDRKLPQGYRSIDLTVKLGSRVITDPSLSKTDSYKRLHPEKDHGDLLASCPEDEALTPGDECMDGILDESLLETCPIQSP
LQVFAGMGGLALIAERLPMLYPEVIQQVSAPVVTSTTQEKPKDSDQFEWVTIEQSGELVYEAPETVAAEPPPIKSAVQTMSPIPAHSLAA
FGLFLRLPGYAEVLLKERKHAQCLLRLVLGVTDDGEGSHILQSPSANVLPTLPFHVLRSLFSTTPLTTDDGVLLRRMALEIGALHLILVC
LSALSHHSPRVPNSSVNQTEPQVSSSHNPTSTEEQQLYWAKGTGFGTGSTASGWDVEQALTKQRLEEEHVTCLLQVLASYINPVSSAVNG
EAQSSHETRGQNSNALPSVLLELLSQSCLIPAMSSYLRNDSVLDMARHVPLYRALLELLRAIASCAAMVPLLLPLSTENGEEEEEQSECQ
TSVGTLLAKMKTCVDTYTNRLRSKRENVKTGVKPDASDQEPEGLTLLVPDIQKTAEIVYAATTSLRQANQEKKLGEYSKKAAMKPKPLSV
LKSLEEKYVAVMKKLQFDTFEMVSEDEDGKLGFKVNYHYMSQVKNANDANSAARARRLAQEAVTLSTSLPLSSSSSVFVRCDEERLDIMK
VLITGPADTPYANGCFEFDVYFPQDYPSSPPLVNLETTGGHSVRFNPNLYNDGKVCLSILNTWHGRPEEKWNPQTSSFLQVLVSVQSLIL
VAEPYFNEPGYERSRGTPSGTQSSREYDGNIRQATVKWAMLEQIRNPSPCFKEVIHKHFYLKRVEIMAQCEEWIADIQQYSSDKRVGRTM

--------------------------------------------------------------
>66241_66241_3_PLEKHB2-BIRC6_PLEKHB2_chr2_131897848_ENST00000409158_BIRC6_chr2_32715108_ENST00000421745_length(transcript)=8590nt_BP=1116nt
ATACTTTAGGTTATAACTTAATGCAATGTACTTTATATTGCTGCTCAAATTGTCCCAGGCGCGGCCCCCGGAAGCTCTCTGGGTAGATCC
CTGCGCCCTTGGACGCCCGGTCCTTCAGTTTTTTGAGCACCTCAAGCTTCTGGCCTACAAAACGCTCCCGGCTCAGCTGGAGCTTTCTGC
GCCCGGGTCCTAGAGTCGCCCATTTCTCTAAGGCGCCTTGGCCCTATTTTTAGAGAGCGGTATTTAGAAACCAAGATTAGGGTGCTAACA
ATTTTTTTTTAAATTTTTATATTTTTAAGACAGGATCTCACTTTGTAACACTTCCTTTTAGTGGAAGCGCCGACCTCCTGGGAGACCCAC
GCCCCCTGCCGCCTTCCGTCCCGTTTCTCAGAAAACCACCCAGACACCCCGCCCCACCGGCCGGGGCCCGCCGCGCATGCGCGCCGAGGC
GTGACGTCAGAACGGCGGCCAGGACGCCGGACGTGCGGCAGTTGCAGGCGAGCAGGCGAGGAATCGCCGTGGCGTCTTGGTGTTCTCCAC
GCTGGTTCGCAGGTGAAGAGATGGCGTTTGTGAAGAGTGGCTGGTTGCTGCGACAGAGTACTATTTTGAAGCGCTGGAAGAAGAACTGGT
TTGATCTGTGGTCGGATGGTCACCTGATCTATTATGATGACCAGACTCGGCAGAATATCGAGGATAAGGTCCACATGCCAATGGACTGCA
TCAACATCCGCACGGGGCAGGAATGTCGGGATACTCAGCCCCCGGATGGAAAGTCAAAAGACTGCATGCTCCAGATTGTTTGTCGAGATG
GGAAAACAATTAGTCTTTGTGCAGAAAGCACAGATGATTGCTTGGCCTGGAAATTTACACTCCAAGATTCTAGGACAAACACAGCGTATG
TGGGCTCTGCAGTCATGACCGATGAGACATCCGTGGTTTCCTCACCTCCACCATACACGGCCTATGCTGCACCGGCCCCTGAGGTAGGGA
GAACCCTGAGCCTCCAGCAGGCTTATGGCTATGGGCCATACGGTGGTGCGTACCCGCCAGGAACTCAAGTTGTCTACGCTGCGAATGGGC
AGGCGTATGCCGTGCCCTACCAGTACCCATATGCAGCATCAATAACTAGCTTTCTCACAGTGTTAGCTTGGTATCCCAATACTTTGCTCC
GGACATGGTGCCTTGTGCTTCATAGCCTAACACTCATGACAAACATGCAGCTTAATTCTGGTTCCAGCAGTGCCATTGGAACTCAGGAGA
GTACTGCTCATTTGTTGGTTTCAGATCCAAACCTAATTCATGTATTAGTGAAATTTCTTTCTGGCACCAGTCCACATGGAACAAATCAAC
ACAGTCCACAGGTTGGTCCTACAGCTACACAAGCTATGCAAGAATTTCTTACTCGATTACAAGTGCATCTTTCTTCAACATGTCCTCAGA
TATTCAGTGAATTTTTGCTCAAGCTAATTCATATACTTTCAACTGAAAGGGGTGCTTTCCAGACAGGCCAAGGACCTCTCGATGCCCAAG
TGAAGCTCTTAGAATTCACTCTGGAGCAGAATTTTGAAGTCGTTTCAGTTAGTACTATTTCTGCCGTGATAGAATCGGTTACATTTTTAG
TGCACCACTATATCACTTGCTCAGACAAAGTAATGTCAAGAAGTGGATCAGATAGCTCCGTGGGTGCTCGAGCATGCTTTGGGGGACTCT
TTGCCAATCTTATTCGTCCGGGTGATGCAAAAGCAGTTTGTGGCGAAATGACAAGAGATCAACTCATGTTTGATTTGTTAAAACTTGTTA
ACATTTTAGTGCAGCTGCCTCTTTCAGGCAATAGGGAATACAGTGCAAGAGTGTCTGTGACCACAAATACAACAGATAGTGTTTCAGATG
AAGAAAAAGTCTCAGGAGGCAAAGATGGCAATGGAAGCAGTACCAGTGTTCAAGGATCGCCTGCATATGTTGCTGACTTAGTCTTAGCCA
ACCAACAAATTATGAGCCAGATTTTGTCTGCTCTGGGCCTGTGTAATAGCAGTGCCATGGCAATGATAATTGGAGCAAGTGGATTACATC
TCACTAAACATGAAAACTTTCATGGTGGGTTGGATGCCATATCAGTTGGGGATGGATTATTTACCATACTGACAACCCTTAGTAAAAAAG
CTTCTACAGTCCACATGATGCTGCAGCCAATTTTAACATACATGGCCTGTGGATATATGGGCAGACAAGGCTCTCTTGCTACTTGCCAGT
TATCTGAGCCATTATTGTGGTTCATTTTGAGAGTATTGGATACTAGTGATGCCTTGAAAGCATTTCATGATATGGGTGGTGTTCAGCTCA
TATGCAATAATATGGTTACTAGTACAAGGGCTATTGTGAACACTGCAAGAAGTATGGTATCAACTATTATGAAATTTCTTGACTCTGGTC
CAAATAAAGCTGTTGACAGCACATTGAAAACAAGAATACTAGCTTCTGAGCCTGACAATGCTGAAGGGATTCATAACTTTGCACCCCTCG
GTACAATCACATCTAGCAGTCCTACTGCCCAACCAGCTGAAGTGCTATTGCAGGCCACACCTCCTCACAGAAGAGCTCGCTCTGCTGCTT
GGTCCTACATCTTTCTTCCAGAGGAGGCTTGGTGTGACCTTACCATTCACCTTCCTGCAGCAGTGCTGCTTAAGGAGATACATATCCAGC
CTCATCTTGCATCTCTTGCAACCTGCCCTTCCTCAGTGTCTGTTGAAGTAAGTGCAGATGGGGTAAATATGCTACCTTTGTCCACTCCTG
TTGTCACAAGTGGCCTCACCTACATAAAAATTCAGCTTGTAAAAGCCGAAGTAGCTTCTGCTGTCTGCCTTAGACTACATCGTCCACGGG
ATGCCAGCACATTAGGCCTTTCACAAATTAAATTATTGGGGCTCACTGCTTTTGGTACCACCTCTTCTGCAACAGTTAATAATCCATTCC
TTCCATCTGAAGATCAGGTATCCAAAACAAGTATTGGATGGTTACGGTTATTACATCATTGCCTTACTCACATAAGTGATCTAGAAGGAA
TGATGGCAAGTGCAGCTGCACCTACTGCTAATCTGCTGCAGACTTGTGCGGCCTTATTGATGTCACCTTACTGTGGAATGCATTCACCCA
ACATCGAGGTTGTGCTTGTAAAGATAGGACTGCAGTCTACTAGAATTGGCCTGAAGCTCATAGACATTCTCCTGAGAAATTGTGCAGCAT
CAGGCAGTGATCCTACAGATTTGAATAGTCCTTTACTTTTTGGAAGACTAAATGGACTCTCTTCTGACTCTACGATAGATATTCTTTACC
AGCTTGGAACAACTCAGGATCCTGGTACAAAAGACAGAATTCAGGCCTTGTTAAAATGGGTTAGTGATTCTGCAAGAGTGGCTGCTATGA
AGAGAAGTGGCAGGATGAACTACATGTGTCCTAACTCCTCAACAGTAGAGTATGGTCTTCTGATGCCATCTCCTTCTCATTTGCACTGTG
TAGCAGCCATTCTGTGGCATAGTTATGAGCTGCTTGTAGAATATGACTTACCAGCACTCCTGGACCAAGAGCTCTTTGAGTTACTTTTTA
ATTGGTCCATGTCTCTTCCCTGCAATATGGTTTTGAAGAAAGCTGTTGACAGTCTACTTTGCTCAATGTGTCACGTACACCCAAACTATT
TTTCTTTGCTCATGGGCTGGATGGGAATTACCCCTCCTCCAGTGCAATGTCATCATAGACTGTCCATGACAGATGATAGCAAAAAGCAGG
ATCTTAGTTCATCTTTAACAGATGACTCTAAAAATGCACAAGCACCTCTCGCATTAACTGAATCACATTTGGCTACCCTTGCTTCCTCTT
CTCAATCTCCTGAAGCTATTAAACAATTACTAGACTCAGGTTTGCCTTCTCTTCTTGTGAGGAGTCTGGCTAGTTTCTGCTTTAGCCACA
TTTCTAGCTCAGAAAGCATTGCCCAGTCAATAGATATTTCCCAGGACAAACTCAGGCGCCATCATGTCCCACAACAATGTAATAAGATGC
CTATCACAGCCGACCTAGTTGCTCCTATTCTTAGGTTTTTGACAGAAGTTGGCAATAGCCATATTATGAAAGATTGGCTTGGTGGTTCTG
AAGTCAATCCACTATGGACAGCACTTCTGTTTTTATTGTGTCACTCTGGGTCCACTTCTGGAAGCCATAATTTAGGTGCACAACAGACCA
GTGCAAGATCAGCTTCTCTTTCTTCAGCTGCTACAACAGGACTGACTACTCAACAGCGCACAGCAATTGAGAATGCAACTGTTGCGTTCT
TTCTACAGTGCATTTCATGCCATCCTAATAATCAAAAGCTGATGGCACAGGTTCTTTGTGAACTATTTCAGACATCTCCTCAAAGAGGGA
ACCTTCCAACATCTGGGAACATTTCAGGGTTTATACGAAGATTATTTTTACAGTTGATGCTGGAAGATGAGAAAGTGACAATGTTTCTTC
AGTCTCCATGTCCACTGTACAAAGGTAGAATTAATGCTACTAGCCACGTCATCCAGCATCCAATGTATGGAGCAGGCCACAAATTCCGTA
CTCTTCATTTGCCAGTCTCAACAACATTATCAGATGTTCTTGACAGAGTGTCAGATACTCCAAGTATCACAGCTAAATTAATTAGTGAAC
AAAAAGATGACAAAGAAAAGAAAAACCATGAAGAGAAAGAAAAAGTTAAAGCGGAAAATGGATTTCAAGACAATTACAGTGTTGTTGTTG
CCTCTGGGCTGAAGTCTCAATCTAAACGTGCTGTGTCAGCTACACCACCTCGCCCACCATCCAGGAGGGGGAGGACAATACCTGATAAAA
TAGGAAGTACTTCAGGAGCAGAGGCTGCCAACAAAATAATTACTGTCCCAGTGTTTCACCTGTTTCACAAACTCTTGGCAGGCCAGCCAT
TGCCAGCTGAAATGACACTTGCCCAGCTTTTAACTCTCCTATATGACCGAAAACTTCCTCAGGGTTACCGCTCAATAGATCTGACTGTTA
AATTGGGATCAAGAGTTATAACAGACCCCAGTCTATCAAAAACAGATTCTTATAAAAGACTACACCCTGAAAAAGATCATGGAGACTTAC
TTGCTAGCTGTCCAGAAGATGAGGCTCTCACTCCAGGTGATGAATGCATGGATGGGATACTGGATGAATCTTTGCTTGAAACCTGTCCAA
TTCAGTCACCATTACAAGTTTTTGCAGGAATGGGTGGACTGGCTCTTATTGCTGAAAGACTACCCATGCTATATCCAGAAGTAATTCAAC
AGGTGAGTGCTCCAGTTGTAACATCTACCACTCAGGAAAAGCCGAAGGATAGCGATCAGTTTGAATGGGTGACCATTGAACAGTCAGGGG
AGTTAGTTTATGAAGCACCAGAAACTGTTGCGGCTGAACCTCCACCTATCAAGTCAGCAGTACAGACCATGTCTCCCATACCTGCCCATT
CTTTGGCTGCTTTTGGATTATTTCTTCGTCTTCCGGGCTATGCGGAAGTGCTACTGAAAGAGAGAAAACATGCCCAGTGCCTTCTTCGAT
TGGTATTGGGAGTGACAGATGATGGAGAAGGAAGTCATATTCTTCAATCTCCATCAGCCAATGTGCTTCCAACCCTTCCTTTCCACGTCC
TTCGTAGCTTGTTTAGCACTACACCTTTGACAACTGATGATGGTGTACTTCTAAGGCGGATGGCATTGGAAATTGGAGCCTTACACCTCA
TTCTTGTCTGTCTCTCTGCTTTGAGCCACCATTCCCCACGAGTTCCAAACTCTAGCGTGAATCAAACTGAGCCACAGGTGTCAAGCTCTC
ATAACCCTACATCAACAGAAGAACAACAGTTATATTGGGCCAAAGGGACTGGCTTTGGAACAGGCTCTACAGCTTCTGGGTGGGATGTGG
AACAAGCCTTAACTAAGCAAAGGCTGGAAGAGGAACATGTTACCTGCCTTCTGCAGGTTCTTGCCAGTTACATAAATCCCGTCAGTAGTG
CGGTAAATGGAGAAGCTCAGTCATCTCATGAGACTAGAGGGCAGAACAGTAATGCCCTTCCTTCTGTACTTCTCGAGCTTCTCAGTCAGT
CCTGCCTCATCCCAGCCATGTCATCTTATCTACGAAATGATTCAGTTCTGGACATGGCAAGACATGTGCCACTCTATCGGGCACTGCTGG
AATTGCTTCGGGCCATTGCTTCTTGTGCTGCCATGGTGCCCCTATTGTTGCCCCTTTCTACAGAGAACGGTGAAGAGGAAGAAGAACAGT
CAGAATGTCAAACTTCTGTTGGTACATTGTTAGCCAAAATGAAGACCTGTGTTGATACCTATACCAACCGTTTAAGATCTAAAAGGGAAA
ATGTTAAAACAGGAGTAAAACCAGATGCGTCTGATCAAGAACCAGAAGGACTTACTCTTTTGGTACCAGACATCCAAAAGACTGCTGAGA
TAGTTTATGCAGCCACCACCAGTTTGCGGCAAGCAAATCAGGAAAAAAAACTGGGTGAATACTCCAAGAAGGCGGCTATGAAACCCAAAC
CTTTGTCAGTATTAAAGTCACTTGAAGAAAAATATGTGGCTGTTATGAAGAAATTACAGTTTGATACGTTTGAAATGGTTTCTGAAGATG
AAGATGGGAAATTGGGATTTAAAGTAAATTACCACTACATGTCTCAGGTGAAAAATGCTAATGATGCGAACAGTGCTGCCAGAGCTCGCC
GCCTTGCCCAGGAAGCTGTGACGCTTTCAACCTCACTGCCTCTGTCTTCATCCTCTAGTGTGTTTGTACGCTGTGATGAGGAGCGACTTG
ATATCATGAAGGTTCTAATAACTGGTCCAGCGGACACCCCTTATGCAAATGGCTGCTTTGAGTTTGATGTGTATTTTCCTCAAGATTATC
CCAGTTCACCCCCTCTTGTGAATCTAGAGACAACTGGTGGTCATAGCGTGCGATTCAATCCAAACCTTTATAATGATGGCAAGGTTTGTT
TAAGCATCTTAAACACGTGGCATGGAAGACCAGAAGAGAAGTGGAATCCTCAGACCTCAAGCTTTTTGCAAGTGTTGGTGTCTGTCCAGT
CCCTTATATTAGTAGCTGAGCCTTATTTTAATGAACCGGGATATGAACGGTCTAGAGGCACTCCCAGTGGCACACAGAGTTCTCGAGAAT
ATGATGGAAACATTCGACAAGCAACAGTTAAGTGGGCAATGCTAGAACAAATCAGAAACCCTTCACCATGTTTTAAAGAGGTAATACACA
AACATTTTTACTTGAAAAGAGTTGAGATAATGGCCCAATGTGAGGAGTGGATTGCGGATATCCAGCAGTACAGCAGTGATAAGCGGGTAG
GCAGGACTATGTCTCACCATGCAGCAGCTCTCAAGCGTCACACTGCTCAGCTCCGCGAAGAGTTGCTGAAACTTCCCTGCCCTGAAGGCT
TGGATCCTGACACTGACGATGCCCCAGAGGTGTGCAGAGCCACAACAGGTGCTGAGGAGACTCTAATGCATGATCAGGTTAAACCCAGCA
GCAGCAAAGAACTCCCCAGTGACTTCCAGTTATGAGCTGCATTGATGTGGACTTCATAGACACAAAGGCTTCGAAGCACAAGCCAAATAT
GTCAATATTTGTATGTAAGAAACTAATTATGTAATAGGTAATGAAACTGAAACTATACTATGCCCTTAAGGAGATCCAGTTTAATTCAAG
GTGATCTTTTATTTACCTGTACAGGAGTGTAAACTTTTTTGTGCTTTTATTTTTCAATTGTGAGAACCACTGATTGGTATGTTCAACAAA
TTTGTGTATACAAAGAAATGGATAAATCACTGCTATATAAGGGAAACTACCTTAGGAAAGAATGTTTACTGAATGTTTATTTTATTTTAT
TTTTTTTTTACTATAGAGTGAGGGGTTGTTAACAAAGAATATATATTGGTCATTCTTACAACTACTATTTAAAGTCAGCAACTTTTCACT
GAATTTGATAGATTTTATGTTTGGCCATATCTTCATGCTCACATTTGATTTCTGAAGACCTCCTACATACACTTCAATAAAAGTTAAATG
GACATACTCCCTCTTTTTTGATTTACTGGTACATTTTTAAAATAATAAATCTGCCATAAAATGCATTATATCTGGAGACTTGCACTTGTA
TGGATGAATTTATTACATTCAACATATTTAATTTTATGCCTTCTAATTCTAAGATGCAGAAAAAAATAAATGAACATGATTTTATTCTAT
GCCAACATTTGGGCCTCTGAATGTATCTGTTATTTGAATTTAAGTATTTGAAAAGGAATGGTCAATTTGAAAGTCATTCTAAACTGATTT
TTTTTTTCTAAAGGGCTCCTTTTTTCCTGGACTATGTGGTTTTATGACTAAAGTCACATGTATGTATTAAACATTGAGGCTCTGTAGAGG
AGAGAGGATGTACCTCTCTGGTGCTGTTACAGTACATTCTGTACCTGCCATACAGGCTCATTTTCATGCAAATTCTTCCTAGAGCCAAAT

>66241_66241_3_PLEKHB2-BIRC6_PLEKHB2_chr2_131897848_ENST00000409158_BIRC6_chr2_32715108_ENST00000421745_length(amino acids)=2415AA_BP=256
MGDPRPLPPSVPFLRKPPRHPAPPAGARRACAPRRDVRTAARTPDVRQLQASRRGIAVASWCSPRWFAGEEMAFVKSGWLLRQSTILKRW
KKNWFDLWSDGHLIYYDDQTRQNIEDKVHMPMDCINIRTGQECRDTQPPDGKSKDCMLQIVCRDGKTISLCAESTDDCLAWKFTLQDSRT
NTAYVGSAVMTDETSVVSSPPPYTAYAAPAPEVGRTLSLQQAYGYGPYGGAYPPGTQVVYAANGQAYAVPYQYPYAASITSFLTVLAWYP
NTLLRTWCLVLHSLTLMTNMQLNSGSSSAIGTQESTAHLLVSDPNLIHVLVKFLSGTSPHGTNQHSPQVGPTATQAMQEFLTRLQVHLSS
TCPQIFSEFLLKLIHILSTERGAFQTGQGPLDAQVKLLEFTLEQNFEVVSVSTISAVIESVTFLVHHYITCSDKVMSRSGSDSSVGARAC
FGGLFANLIRPGDAKAVCGEMTRDQLMFDLLKLVNILVQLPLSGNREYSARVSVTTNTTDSVSDEEKVSGGKDGNGSSTSVQGSPAYVAD
LVLANQQIMSQILSALGLCNSSAMAMIIGASGLHLTKHENFHGGLDAISVGDGLFTILTTLSKKASTVHMMLQPILTYMACGYMGRQGSL
ATCQLSEPLLWFILRVLDTSDALKAFHDMGGVQLICNNMVTSTRAIVNTARSMVSTIMKFLDSGPNKAVDSTLKTRILASEPDNAEGIHN
FAPLGTITSSSPTAQPAEVLLQATPPHRRARSAAWSYIFLPEEAWCDLTIHLPAAVLLKEIHIQPHLASLATCPSSVSVEVSADGVNMLP
LSTPVVTSGLTYIKIQLVKAEVASAVCLRLHRPRDASTLGLSQIKLLGLTAFGTTSSATVNNPFLPSEDQVSKTSIGWLRLLHHCLTHIS
DLEGMMASAAAPTANLLQTCAALLMSPYCGMHSPNIEVVLVKIGLQSTRIGLKLIDILLRNCAASGSDPTDLNSPLLFGRLNGLSSDSTI
DILYQLGTTQDPGTKDRIQALLKWVSDSARVAAMKRSGRMNYMCPNSSTVEYGLLMPSPSHLHCVAAILWHSYELLVEYDLPALLDQELF
ELLFNWSMSLPCNMVLKKAVDSLLCSMCHVHPNYFSLLMGWMGITPPPVQCHHRLSMTDDSKKQDLSSSLTDDSKNAQAPLALTESHLAT
LASSSQSPEAIKQLLDSGLPSLLVRSLASFCFSHISSSESIAQSIDISQDKLRRHHVPQQCNKMPITADLVAPILRFLTEVGNSHIMKDW
LGGSEVNPLWTALLFLLCHSGSTSGSHNLGAQQTSARSASLSSAATTGLTTQQRTAIENATVAFFLQCISCHPNNQKLMAQVLCELFQTS
PQRGNLPTSGNISGFIRRLFLQLMLEDEKVTMFLQSPCPLYKGRINATSHVIQHPMYGAGHKFRTLHLPVSTTLSDVLDRVSDTPSITAK
LISEQKDDKEKKNHEEKEKVKAENGFQDNYSVVVASGLKSQSKRAVSATPPRPPSRRGRTIPDKIGSTSGAEAANKIITVPVFHLFHKLL
AGQPLPAEMTLAQLLTLLYDRKLPQGYRSIDLTVKLGSRVITDPSLSKTDSYKRLHPEKDHGDLLASCPEDEALTPGDECMDGILDESLL
ETCPIQSPLQVFAGMGGLALIAERLPMLYPEVIQQVSAPVVTSTTQEKPKDSDQFEWVTIEQSGELVYEAPETVAAEPPPIKSAVQTMSP
IPAHSLAAFGLFLRLPGYAEVLLKERKHAQCLLRLVLGVTDDGEGSHILQSPSANVLPTLPFHVLRSLFSTTPLTTDDGVLLRRMALEIG
ALHLILVCLSALSHHSPRVPNSSVNQTEPQVSSSHNPTSTEEQQLYWAKGTGFGTGSTASGWDVEQALTKQRLEEEHVTCLLQVLASYIN
PVSSAVNGEAQSSHETRGQNSNALPSVLLELLSQSCLIPAMSSYLRNDSVLDMARHVPLYRALLELLRAIASCAAMVPLLLPLSTENGEE
EEEQSECQTSVGTLLAKMKTCVDTYTNRLRSKRENVKTGVKPDASDQEPEGLTLLVPDIQKTAEIVYAATTSLRQANQEKKLGEYSKKAA
MKPKPLSVLKSLEEKYVAVMKKLQFDTFEMVSEDEDGKLGFKVNYHYMSQVKNANDANSAARARRLAQEAVTLSTSLPLSSSSSVFVRCD
EERLDIMKVLITGPADTPYANGCFEFDVYFPQDYPSSPPLVNLETTGGHSVRFNPNLYNDGKVCLSILNTWHGRPEEKWNPQTSSFLQVL
VSVQSLILVAEPYFNEPGYERSRGTPSGTQSSREYDGNIRQATVKWAMLEQIRNPSPCFKEVIHKHFYLKRVEIMAQCEEWIADIQQYSS

--------------------------------------------------------------
>66241_66241_4_PLEKHB2-BIRC6_PLEKHB2_chr2_131897848_ENST00000409279_BIRC6_chr2_32715108_ENST00000421745_length(transcript)=8801nt_BP=1327nt
AAAAAAAAGCTAAAGCAGAAAACAAAAGTGGCCCATGGTCTCAGCTTCCAGATAATAACTATTGATTTCAAAAAATAAAATGGCCTGGGA
TTACAGGCATGAGCTGCTGCGCCCGGCCAATTTTTGTATTTTTAGTAGAGATGAGGTTTCACCATGTTGGCCAGGCTGGTCTCGAATTCC
TGACCTCAGGTGATCCACCCTCCTCGGCCTGAGCCACCGTGCCCAGCCGTGACTGTTTCTTCTAATTTATCACTTTTAAAGTCTCATTTA
ACTTTTTTTCCATACAGAAGATTTAAATTTTTATGGAGTTGACTTTATGAACCTTTTTCTTGATGACTTTTGTTTTTTTGCCCTGACCTG
GCCACTCCACGTCACTCACTGCTGACACCAGTGCAGCACCCCTGCCTGGGCCATGTGGACCCCACTGGGAACGCCAAATGTAGGCACCTC
AGGGCTCCAGCAAGCCACGAGAATCCCCCATGTCCTTGACAGAGCTAAATCCTGTGTCCCTGGGGCTGCTTTATGTTTGTTGAGTGGTGT
TAGACTCGGTCAGGTGGGCTGGGTGGTGAGGCTGAAGGCGAGTGTGGGAGGAAGGGAGGGGGTACAGAGTGCGGGGCACATGAACCCCAA
TGAGGAGGTGTTTGTTAAATGCCAGGGGGGCACTGAGCTAAAATGGCCTTGGGCCCTTCCTCAGCTGATGCTGAAGGGGATAAGGATAGA
GACTCGGGCCGGACAGGCTATTCTCTTTCTGGGTATGATTTTGAACCTGCCTGTTTTTGTTCTGTAGGTGAAGAGATGGCGTTTGTGAAG
AGTGGCTGGTTGCTGCGACAGAGTACTATTTTGAAGCGCTGGAAGAAGAACTGGTTTGATCTGTGGTCGGATGGTCACCTGATCTATTAT
GATGACCAGACTCGGCAGAATATCGAGGATAAGGTCCACATGCCAATGGACTGCATCAACATCCGCACGGGGCAGGAATGTCGGGATACT
CAGCCCCCGGATGGAAAGTCAAAAGACTGCATGCTCCAGATTGTTTGTCGAGATGGGAAAACAATTAGTCTTTGTGCAGAAAGCACAGAT
GATTGCTTGGCCTGGAAATTTACACTCCAAGATTCTAGGACAAACACAGCGTATGTGGGCTCTGCAGTCATGACCGATGAGACATCCGTG
GTTTCCTCACCTCCACCATACACGGCCTATGCTGCACCGGCCCCTGAGCAGGCTTATGGCTATGGGCCATACGGTGGTGCGTACCCGCCA
GGAACTCAAGTTGTCTACGCTGCGAATGGGCAGGCGTATGCCGTGCCCTACCAGTACCCATATGCAGCATCAATAACTAGCTTTCTCACA
GTGTTAGCTTGGTATCCCAATACTTTGCTCCGGACATGGTGCCTTGTGCTTCATAGCCTAACACTCATGACAAACATGCAGCTTAATTCT
GGTTCCAGCAGTGCCATTGGAACTCAGGAGAGTACTGCTCATTTGTTGGTTTCAGATCCAAACCTAATTCATGTATTAGTGAAATTTCTT
TCTGGCACCAGTCCACATGGAACAAATCAACACAGTCCACAGGTTGGTCCTACAGCTACACAAGCTATGCAAGAATTTCTTACTCGATTA
CAAGTGCATCTTTCTTCAACATGTCCTCAGATATTCAGTGAATTTTTGCTCAAGCTAATTCATATACTTTCAACTGAAAGGGGTGCTTTC
CAGACAGGCCAAGGACCTCTCGATGCCCAAGTGAAGCTCTTAGAATTCACTCTGGAGCAGAATTTTGAAGTCGTTTCAGTTAGTACTATT
TCTGCCGTGATAGAATCGGTTACATTTTTAGTGCACCACTATATCACTTGCTCAGACAAAGTAATGTCAAGAAGTGGATCAGATAGCTCC
GTGGGTGCTCGAGCATGCTTTGGGGGACTCTTTGCCAATCTTATTCGTCCGGGTGATGCAAAAGCAGTTTGTGGCGAAATGACAAGAGAT
CAACTCATGTTTGATTTGTTAAAACTTGTTAACATTTTAGTGCAGCTGCCTCTTTCAGGCAATAGGGAATACAGTGCAAGAGTGTCTGTG
ACCACAAATACAACAGATAGTGTTTCAGATGAAGAAAAAGTCTCAGGAGGCAAAGATGGCAATGGAAGCAGTACCAGTGTTCAAGGATCG
CCTGCATATGTTGCTGACTTAGTCTTAGCCAACCAACAAATTATGAGCCAGATTTTGTCTGCTCTGGGCCTGTGTAATAGCAGTGCCATG
GCAATGATAATTGGAGCAAGTGGATTACATCTCACTAAACATGAAAACTTTCATGGTGGGTTGGATGCCATATCAGTTGGGGATGGATTA
TTTACCATACTGACAACCCTTAGTAAAAAAGCTTCTACAGTCCACATGATGCTGCAGCCAATTTTAACATACATGGCCTGTGGATATATG
GGCAGACAAGGCTCTCTTGCTACTTGCCAGTTATCTGAGCCATTATTGTGGTTCATTTTGAGAGTATTGGATACTAGTGATGCCTTGAAA
GCATTTCATGATATGGGTGGTGTTCAGCTCATATGCAATAATATGGTTACTAGTACAAGGGCTATTGTGAACACTGCAAGAAGTATGGTA
TCAACTATTATGAAATTTCTTGACTCTGGTCCAAATAAAGCTGTTGACAGCACATTGAAAACAAGAATACTAGCTTCTGAGCCTGACAAT
GCTGAAGGGATTCATAACTTTGCACCCCTCGGTACAATCACATCTAGCAGTCCTACTGCCCAACCAGCTGAAGTGCTATTGCAGGCCACA
CCTCCTCACAGAAGAGCTCGCTCTGCTGCTTGGTCCTACATCTTTCTTCCAGAGGAGGCTTGGTGTGACCTTACCATTCACCTTCCTGCA
GCAGTGCTGCTTAAGGAGATACATATCCAGCCTCATCTTGCATCTCTTGCAACCTGCCCTTCCTCAGTGTCTGTTGAAGTAAGTGCAGAT
GGGGTAAATATGCTACCTTTGTCCACTCCTGTTGTCACAAGTGGCCTCACCTACATAAAAATTCAGCTTGTAAAAGCCGAAGTAGCTTCT
GCTGTCTGCCTTAGACTACATCGTCCACGGGATGCCAGCACATTAGGCCTTTCACAAATTAAATTATTGGGGCTCACTGCTTTTGGTACC
ACCTCTTCTGCAACAGTTAATAATCCATTCCTTCCATCTGAAGATCAGGTATCCAAAACAAGTATTGGATGGTTACGGTTATTACATCAT
TGCCTTACTCACATAAGTGATCTAGAAGGAATGATGGCAAGTGCAGCTGCACCTACTGCTAATCTGCTGCAGACTTGTGCGGCCTTATTG
ATGTCACCTTACTGTGGAATGCATTCACCCAACATCGAGGTTGTGCTTGTAAAGATAGGACTGCAGTCTACTAGAATTGGCCTGAAGCTC
ATAGACATTCTCCTGAGAAATTGTGCAGCATCAGGCAGTGATCCTACAGATTTGAATAGTCCTTTACTTTTTGGAAGACTAAATGGACTC
TCTTCTGACTCTACGATAGATATTCTTTACCAGCTTGGAACAACTCAGGATCCTGGTACAAAAGACAGAATTCAGGCCTTGTTAAAATGG
GTTAGTGATTCTGCAAGAGTGGCTGCTATGAAGAGAAGTGGCAGGATGAACTACATGTGTCCTAACTCCTCAACAGTAGAGTATGGTCTT
CTGATGCCATCTCCTTCTCATTTGCACTGTGTAGCAGCCATTCTGTGGCATAGTTATGAGCTGCTTGTAGAATATGACTTACCAGCACTC
CTGGACCAAGAGCTCTTTGAGTTACTTTTTAATTGGTCCATGTCTCTTCCCTGCAATATGGTTTTGAAGAAAGCTGTTGACAGTCTACTT
TGCTCAATGTGTCACGTACACCCAAACTATTTTTCTTTGCTCATGGGCTGGATGGGAATTACCCCTCCTCCAGTGCAATGTCATCATAGA
CTGTCCATGACAGATGATAGCAAAAAGCAGGATCTTAGTTCATCTTTAACAGATGACTCTAAAAATGCACAAGCACCTCTCGCATTAACT
GAATCACATTTGGCTACCCTTGCTTCCTCTTCTCAATCTCCTGAAGCTATTAAACAATTACTAGACTCAGGTTTGCCTTCTCTTCTTGTG
AGGAGTCTGGCTAGTTTCTGCTTTAGCCACATTTCTAGCTCAGAAAGCATTGCCCAGTCAATAGATATTTCCCAGGACAAACTCAGGCGC
CATCATGTCCCACAACAATGTAATAAGATGCCTATCACAGCCGACCTAGTTGCTCCTATTCTTAGGTTTTTGACAGAAGTTGGCAATAGC
CATATTATGAAAGATTGGCTTGGTGGTTCTGAAGTCAATCCACTATGGACAGCACTTCTGTTTTTATTGTGTCACTCTGGGTCCACTTCT
GGAAGCCATAATTTAGGTGCACAACAGACCAGTGCAAGATCAGCTTCTCTTTCTTCAGCTGCTACAACAGGACTGACTACTCAACAGCGC
ACAGCAATTGAGAATGCAACTGTTGCGTTCTTTCTACAGTGCATTTCATGCCATCCTAATAATCAAAAGCTGATGGCACAGGTTCTTTGT
GAACTATTTCAGACATCTCCTCAAAGAGGGAACCTTCCAACATCTGGGAACATTTCAGGGTTTATACGAAGATTATTTTTACAGTTGATG
CTGGAAGATGAGAAAGTGACAATGTTTCTTCAGTCTCCATGTCCACTGTACAAAGGTAGAATTAATGCTACTAGCCACGTCATCCAGCAT
CCAATGTATGGAGCAGGCCACAAATTCCGTACTCTTCATTTGCCAGTCTCAACAACATTATCAGATGTTCTTGACAGAGTGTCAGATACT
CCAAGTATCACAGCTAAATTAATTAGTGAACAAAAAGATGACAAAGAAAAGAAAAACCATGAAGAGAAAGAAAAAGTTAAAGCGGAAAAT
GGATTTCAAGACAATTACAGTGTTGTTGTTGCCTCTGGGCTGAAGTCTCAATCTAAACGTGCTGTGTCAGCTACACCACCTCGCCCACCA
TCCAGGAGGGGGAGGACAATACCTGATAAAATAGGAAGTACTTCAGGAGCAGAGGCTGCCAACAAAATAATTACTGTCCCAGTGTTTCAC
CTGTTTCACAAACTCTTGGCAGGCCAGCCATTGCCAGCTGAAATGACACTTGCCCAGCTTTTAACTCTCCTATATGACCGAAAACTTCCT
CAGGGTTACCGCTCAATAGATCTGACTGTTAAATTGGGATCAAGAGTTATAACAGACCCCAGTCTATCAAAAACAGATTCTTATAAAAGA
CTACACCCTGAAAAAGATCATGGAGACTTACTTGCTAGCTGTCCAGAAGATGAGGCTCTCACTCCAGGTGATGAATGCATGGATGGGATA
CTGGATGAATCTTTGCTTGAAACCTGTCCAATTCAGTCACCATTACAAGTTTTTGCAGGAATGGGTGGACTGGCTCTTATTGCTGAAAGA
CTACCCATGCTATATCCAGAAGTAATTCAACAGGTGAGTGCTCCAGTTGTAACATCTACCACTCAGGAAAAGCCGAAGGATAGCGATCAG
TTTGAATGGGTGACCATTGAACAGTCAGGGGAGTTAGTTTATGAAGCACCAGAAACTGTTGCGGCTGAACCTCCACCTATCAAGTCAGCA
GTACAGACCATGTCTCCCATACCTGCCCATTCTTTGGCTGCTTTTGGATTATTTCTTCGTCTTCCGGGCTATGCGGAAGTGCTACTGAAA
GAGAGAAAACATGCCCAGTGCCTTCTTCGATTGGTATTGGGAGTGACAGATGATGGAGAAGGAAGTCATATTCTTCAATCTCCATCAGCC
AATGTGCTTCCAACCCTTCCTTTCCACGTCCTTCGTAGCTTGTTTAGCACTACACCTTTGACAACTGATGATGGTGTACTTCTAAGGCGG
ATGGCATTGGAAATTGGAGCCTTACACCTCATTCTTGTCTGTCTCTCTGCTTTGAGCCACCATTCCCCACGAGTTCCAAACTCTAGCGTG
AATCAAACTGAGCCACAGGTGTCAAGCTCTCATAACCCTACATCAACAGAAGAACAACAGTTATATTGGGCCAAAGGGACTGGCTTTGGA
ACAGGCTCTACAGCTTCTGGGTGGGATGTGGAACAAGCCTTAACTAAGCAAAGGCTGGAAGAGGAACATGTTACCTGCCTTCTGCAGGTT
CTTGCCAGTTACATAAATCCCGTCAGTAGTGCGGTAAATGGAGAAGCTCAGTCATCTCATGAGACTAGAGGGCAGAACAGTAATGCCCTT
CCTTCTGTACTTCTCGAGCTTCTCAGTCAGTCCTGCCTCATCCCAGCCATGTCATCTTATCTACGAAATGATTCAGTTCTGGACATGGCA
AGACATGTGCCACTCTATCGGGCACTGCTGGAATTGCTTCGGGCCATTGCTTCTTGTGCTGCCATGGTGCCCCTATTGTTGCCCCTTTCT
ACAGAGAACGGTGAAGAGGAAGAAGAACAGTCAGAATGTCAAACTTCTGTTGGTACATTGTTAGCCAAAATGAAGACCTGTGTTGATACC
TATACCAACCGTTTAAGATCTAAAAGGGAAAATGTTAAAACAGGAGTAAAACCAGATGCGTCTGATCAAGAACCAGAAGGACTTACTCTT
TTGGTACCAGACATCCAAAAGACTGCTGAGATAGTTTATGCAGCCACCACCAGTTTGCGGCAAGCAAATCAGGAAAAAAAACTGGGTGAA
TACTCCAAGAAGGCGGCTATGAAACCCAAACCTTTGTCAGTATTAAAGTCACTTGAAGAAAAATATGTGGCTGTTATGAAGAAATTACAG
TTTGATACGTTTGAAATGGTTTCTGAAGATGAAGATGGGAAATTGGGATTTAAAGTAAATTACCACTACATGTCTCAGGTGAAAAATGCT
AATGATGCGAACAGTGCTGCCAGAGCTCGCCGCCTTGCCCAGGAAGCTGTGACGCTTTCAACCTCACTGCCTCTGTCTTCATCCTCTAGT
GTGTTTGTACGCTGTGATGAGGAGCGACTTGATATCATGAAGGTTCTAATAACTGGTCCAGCGGACACCCCTTATGCAAATGGCTGCTTT
GAGTTTGATGTGTATTTTCCTCAAGATTATCCCAGTTCACCCCCTCTTGTGAATCTAGAGACAACTGGTGGTCATAGCGTGCGATTCAAT
CCAAACCTTTATAATGATGGCAAGGTTTGTTTAAGCATCTTAAACACGTGGCATGGAAGACCAGAAGAGAAGTGGAATCCTCAGACCTCA
AGCTTTTTGCAAGTGTTGGTGTCTGTCCAGTCCCTTATATTAGTAGCTGAGCCTTATTTTAATGAACCGGGATATGAACGGTCTAGAGGC
ACTCCCAGTGGCACACAGAGTTCTCGAGAATATGATGGAAACATTCGACAAGCAACAGTTAAGTGGGCAATGCTAGAACAAATCAGAAAC
CCTTCACCATGTTTTAAAGAGGTAATACACAAACATTTTTACTTGAAAAGAGTTGAGATAATGGCCCAATGTGAGGAGTGGATTGCGGAT
ATCCAGCAGTACAGCAGTGATAAGCGGGTAGGCAGGACTATGTCTCACCATGCAGCAGCTCTCAAGCGTCACACTGCTCAGCTCCGCGAA
GAGTTGCTGAAACTTCCCTGCCCTGAAGGCTTGGATCCTGACACTGACGATGCCCCAGAGGTGTGCAGAGCCACAACAGGTGCTGAGGAG
ACTCTAATGCATGATCAGGTTAAACCCAGCAGCAGCAAAGAACTCCCCAGTGACTTCCAGTTATGAGCTGCATTGATGTGGACTTCATAG
ACACAAAGGCTTCGAAGCACAAGCCAAATATGTCAATATTTGTATGTAAGAAACTAATTATGTAATAGGTAATGAAACTGAAACTATACT
ATGCCCTTAAGGAGATCCAGTTTAATTCAAGGTGATCTTTTATTTACCTGTACAGGAGTGTAAACTTTTTTGTGCTTTTATTTTTCAATT
GTGAGAACCACTGATTGGTATGTTCAACAAATTTGTGTATACAAAGAAATGGATAAATCACTGCTATATAAGGGAAACTACCTTAGGAAA
GAATGTTTACTGAATGTTTATTTTATTTTATTTTTTTTTTACTATAGAGTGAGGGGTTGTTAACAAAGAATATATATTGGTCATTCTTAC
AACTACTATTTAAAGTCAGCAACTTTTCACTGAATTTGATAGATTTTATGTTTGGCCATATCTTCATGCTCACATTTGATTTCTGAAGAC
CTCCTACATACACTTCAATAAAAGTTAAATGGACATACTCCCTCTTTTTTGATTTACTGGTACATTTTTAAAATAATAAATCTGCCATAA
AATGCATTATATCTGGAGACTTGCACTTGTATGGATGAATTTATTACATTCAACATATTTAATTTTATGCCTTCTAATTCTAAGATGCAG
AAAAAAATAAATGAACATGATTTTATTCTATGCCAACATTTGGGCCTCTGAATGTATCTGTTATTTGAATTTAAGTATTTGAAAAGGAAT
GGTCAATTTGAAAGTCATTCTAAACTGATTTTTTTTTTCTAAAGGGCTCCTTTTTTCCTGGACTATGTGGTTTTATGACTAAAGTCACAT
GTATGTATTAAACATTGAGGCTCTGTAGAGGAGAGAGGATGTACCTCTCTGGTGCTGTTACAGTACATTCTGTACCTGCCATACAGGCTC

>66241_66241_4_PLEKHB2-BIRC6_PLEKHB2_chr2_131897848_ENST00000409279_BIRC6_chr2_32715108_ENST00000421745_length(amino acids)=2377AA_BP=218
MALGPSSADAEGDKDRDSGRTGYSLSGYDFEPACFCSVGEEMAFVKSGWLLRQSTILKRWKKNWFDLWSDGHLIYYDDQTRQNIEDKVHM
PMDCINIRTGQECRDTQPPDGKSKDCMLQIVCRDGKTISLCAESTDDCLAWKFTLQDSRTNTAYVGSAVMTDETSVVSSPPPYTAYAAPA
PEQAYGYGPYGGAYPPGTQVVYAANGQAYAVPYQYPYAASITSFLTVLAWYPNTLLRTWCLVLHSLTLMTNMQLNSGSSSAIGTQESTAH
LLVSDPNLIHVLVKFLSGTSPHGTNQHSPQVGPTATQAMQEFLTRLQVHLSSTCPQIFSEFLLKLIHILSTERGAFQTGQGPLDAQVKLL
EFTLEQNFEVVSVSTISAVIESVTFLVHHYITCSDKVMSRSGSDSSVGARACFGGLFANLIRPGDAKAVCGEMTRDQLMFDLLKLVNILV
QLPLSGNREYSARVSVTTNTTDSVSDEEKVSGGKDGNGSSTSVQGSPAYVADLVLANQQIMSQILSALGLCNSSAMAMIIGASGLHLTKH
ENFHGGLDAISVGDGLFTILTTLSKKASTVHMMLQPILTYMACGYMGRQGSLATCQLSEPLLWFILRVLDTSDALKAFHDMGGVQLICNN
MVTSTRAIVNTARSMVSTIMKFLDSGPNKAVDSTLKTRILASEPDNAEGIHNFAPLGTITSSSPTAQPAEVLLQATPPHRRARSAAWSYI
FLPEEAWCDLTIHLPAAVLLKEIHIQPHLASLATCPSSVSVEVSADGVNMLPLSTPVVTSGLTYIKIQLVKAEVASAVCLRLHRPRDAST
LGLSQIKLLGLTAFGTTSSATVNNPFLPSEDQVSKTSIGWLRLLHHCLTHISDLEGMMASAAAPTANLLQTCAALLMSPYCGMHSPNIEV
VLVKIGLQSTRIGLKLIDILLRNCAASGSDPTDLNSPLLFGRLNGLSSDSTIDILYQLGTTQDPGTKDRIQALLKWVSDSARVAAMKRSG
RMNYMCPNSSTVEYGLLMPSPSHLHCVAAILWHSYELLVEYDLPALLDQELFELLFNWSMSLPCNMVLKKAVDSLLCSMCHVHPNYFSLL
MGWMGITPPPVQCHHRLSMTDDSKKQDLSSSLTDDSKNAQAPLALTESHLATLASSSQSPEAIKQLLDSGLPSLLVRSLASFCFSHISSS
ESIAQSIDISQDKLRRHHVPQQCNKMPITADLVAPILRFLTEVGNSHIMKDWLGGSEVNPLWTALLFLLCHSGSTSGSHNLGAQQTSARS
ASLSSAATTGLTTQQRTAIENATVAFFLQCISCHPNNQKLMAQVLCELFQTSPQRGNLPTSGNISGFIRRLFLQLMLEDEKVTMFLQSPC
PLYKGRINATSHVIQHPMYGAGHKFRTLHLPVSTTLSDVLDRVSDTPSITAKLISEQKDDKEKKNHEEKEKVKAENGFQDNYSVVVASGL
KSQSKRAVSATPPRPPSRRGRTIPDKIGSTSGAEAANKIITVPVFHLFHKLLAGQPLPAEMTLAQLLTLLYDRKLPQGYRSIDLTVKLGS
RVITDPSLSKTDSYKRLHPEKDHGDLLASCPEDEALTPGDECMDGILDESLLETCPIQSPLQVFAGMGGLALIAERLPMLYPEVIQQVSA
PVVTSTTQEKPKDSDQFEWVTIEQSGELVYEAPETVAAEPPPIKSAVQTMSPIPAHSLAAFGLFLRLPGYAEVLLKERKHAQCLLRLVLG
VTDDGEGSHILQSPSANVLPTLPFHVLRSLFSTTPLTTDDGVLLRRMALEIGALHLILVCLSALSHHSPRVPNSSVNQTEPQVSSSHNPT
STEEQQLYWAKGTGFGTGSTASGWDVEQALTKQRLEEEHVTCLLQVLASYINPVSSAVNGEAQSSHETRGQNSNALPSVLLELLSQSCLI
PAMSSYLRNDSVLDMARHVPLYRALLELLRAIASCAAMVPLLLPLSTENGEEEEEQSECQTSVGTLLAKMKTCVDTYTNRLRSKRENVKT
GVKPDASDQEPEGLTLLVPDIQKTAEIVYAATTSLRQANQEKKLGEYSKKAAMKPKPLSVLKSLEEKYVAVMKKLQFDTFEMVSEDEDGK
LGFKVNYHYMSQVKNANDANSAARARRLAQEAVTLSTSLPLSSSSSVFVRCDEERLDIMKVLITGPADTPYANGCFEFDVYFPQDYPSSP
PLVNLETTGGHSVRFNPNLYNDGKVCLSILNTWHGRPEEKWNPQTSSFLQVLVSVQSLILVAEPYFNEPGYERSRGTPSGTQSSREYDGN
IRQATVKWAMLEQIRNPSPCFKEVIHKHFYLKRVEIMAQCEEWIADIQQYSSDKRVGRTMSHHAAALKRHTAQLREELLKLPCPEGLDPD

--------------------------------------------------------------
>66241_66241_5_PLEKHB2-BIRC6_PLEKHB2_chr2_131897848_ENST00000409612_BIRC6_chr2_32715108_ENST00000421745_length(transcript)=8523nt_BP=1049nt
GAAAGAGAGCTGGAGAACTGGGATATCATGAGGAGTTGTAGACAGTTAAACCTGAATTCTAGCTTTTGGAACAAAATAGTAATGTAATTG
TAGCAGTTCTCACTTTTTTATTTTTTATTTTTTTGAGACGGAGTTTCACTCCTGTTGCTTAGGCTGGAGTGCGATGGCGCAGTCTCGGCT
CACTGCAACCTCCGCTTCCCGGGTTCAAGGGAGTCCCCTGCCTCTGCCCCCCAAATAGCTGGGATTACAGGCGTGCGCCACCATGCTCGG
CTAATTTTTTGTATTTTTAATAGAGATGGGGTTTCACTATGTTGGTCAGGCTGGTCTCGAACTCCTGACCTCAGGTGATCCGCCTGCCTT
GGCCTCCCAAAGTGTTGGGATTATAGGCGTGAGCCAACGCGCCTGGCCAATTCTCACTTTTGGACCATCTACTACAGGGCTGTTTGGACA
TACCTCCTTTAATTGTCACAGTAACCCCATGACGTAATTGGTTGTGCCTGGTCATACAGGTGAAGAGATGGCGTTTGTGAAGAGTGGCTG
GTTGCTGCGACAGAGTACTATTTTGAAGCGCTGGAAGAAGAACTGGTTTGATCTGTGGTCGGATGGTCACCTGATCTATTATGATGACCA
GACTCGGCAGAATATCGAGGATAAGGTCCACATGCCAATGGACTGCATCAACATCCGCACGGGGCAGGAATGTCGGGATACTCAGCCCCC
GGATGGAAAGTCAAAAGACTGCATGCTCCAGATTGTTTGTCGAGATGGGAAAACAATTAGTCTTTGTGCAGAAAGCACAGATGATTGCTT
GGCCTGGAAATTTACACTCCAAGATTCTAGGACAAACACAGCGTATGTGGGCTCTGCAGTCATGACCGATGAGACATCCGTGGTTTCCTC
ACCTCCACCATACACGGCCTATGCTGCACCGGCCCCTGAGCAGGCTTATGGCTATGGGCCATACGGTGGTGCGTACCCGCCAGGAACTCA
AGTTGTCTACGCTGCGAATGGGCAGGCGTATGCCGTGCCCTACCAGTACCCATATGCAGCATCAATAACTAGCTTTCTCACAGTGTTAGC
TTGGTATCCCAATACTTTGCTCCGGACATGGTGCCTTGTGCTTCATAGCCTAACACTCATGACAAACATGCAGCTTAATTCTGGTTCCAG
CAGTGCCATTGGAACTCAGGAGAGTACTGCTCATTTGTTGGTTTCAGATCCAAACCTAATTCATGTATTAGTGAAATTTCTTTCTGGCAC
CAGTCCACATGGAACAAATCAACACAGTCCACAGGTTGGTCCTACAGCTACACAAGCTATGCAAGAATTTCTTACTCGATTACAAGTGCA
TCTTTCTTCAACATGTCCTCAGATATTCAGTGAATTTTTGCTCAAGCTAATTCATATACTTTCAACTGAAAGGGGTGCTTTCCAGACAGG
CCAAGGACCTCTCGATGCCCAAGTGAAGCTCTTAGAATTCACTCTGGAGCAGAATTTTGAAGTCGTTTCAGTTAGTACTATTTCTGCCGT
GATAGAATCGGTTACATTTTTAGTGCACCACTATATCACTTGCTCAGACAAAGTAATGTCAAGAAGTGGATCAGATAGCTCCGTGGGTGC
TCGAGCATGCTTTGGGGGACTCTTTGCCAATCTTATTCGTCCGGGTGATGCAAAAGCAGTTTGTGGCGAAATGACAAGAGATCAACTCAT
GTTTGATTTGTTAAAACTTGTTAACATTTTAGTGCAGCTGCCTCTTTCAGGCAATAGGGAATACAGTGCAAGAGTGTCTGTGACCACAAA
TACAACAGATAGTGTTTCAGATGAAGAAAAAGTCTCAGGAGGCAAAGATGGCAATGGAAGCAGTACCAGTGTTCAAGGATCGCCTGCATA
TGTTGCTGACTTAGTCTTAGCCAACCAACAAATTATGAGCCAGATTTTGTCTGCTCTGGGCCTGTGTAATAGCAGTGCCATGGCAATGAT
AATTGGAGCAAGTGGATTACATCTCACTAAACATGAAAACTTTCATGGTGGGTTGGATGCCATATCAGTTGGGGATGGATTATTTACCAT
ACTGACAACCCTTAGTAAAAAAGCTTCTACAGTCCACATGATGCTGCAGCCAATTTTAACATACATGGCCTGTGGATATATGGGCAGACA
AGGCTCTCTTGCTACTTGCCAGTTATCTGAGCCATTATTGTGGTTCATTTTGAGAGTATTGGATACTAGTGATGCCTTGAAAGCATTTCA
TGATATGGGTGGTGTTCAGCTCATATGCAATAATATGGTTACTAGTACAAGGGCTATTGTGAACACTGCAAGAAGTATGGTATCAACTAT
TATGAAATTTCTTGACTCTGGTCCAAATAAAGCTGTTGACAGCACATTGAAAACAAGAATACTAGCTTCTGAGCCTGACAATGCTGAAGG
GATTCATAACTTTGCACCCCTCGGTACAATCACATCTAGCAGTCCTACTGCCCAACCAGCTGAAGTGCTATTGCAGGCCACACCTCCTCA
CAGAAGAGCTCGCTCTGCTGCTTGGTCCTACATCTTTCTTCCAGAGGAGGCTTGGTGTGACCTTACCATTCACCTTCCTGCAGCAGTGCT
GCTTAAGGAGATACATATCCAGCCTCATCTTGCATCTCTTGCAACCTGCCCTTCCTCAGTGTCTGTTGAAGTAAGTGCAGATGGGGTAAA
TATGCTACCTTTGTCCACTCCTGTTGTCACAAGTGGCCTCACCTACATAAAAATTCAGCTTGTAAAAGCCGAAGTAGCTTCTGCTGTCTG
CCTTAGACTACATCGTCCACGGGATGCCAGCACATTAGGCCTTTCACAAATTAAATTATTGGGGCTCACTGCTTTTGGTACCACCTCTTC
TGCAACAGTTAATAATCCATTCCTTCCATCTGAAGATCAGGTATCCAAAACAAGTATTGGATGGTTACGGTTATTACATCATTGCCTTAC
TCACATAAGTGATCTAGAAGGAATGATGGCAAGTGCAGCTGCACCTACTGCTAATCTGCTGCAGACTTGTGCGGCCTTATTGATGTCACC
TTACTGTGGAATGCATTCACCCAACATCGAGGTTGTGCTTGTAAAGATAGGACTGCAGTCTACTAGAATTGGCCTGAAGCTCATAGACAT
TCTCCTGAGAAATTGTGCAGCATCAGGCAGTGATCCTACAGATTTGAATAGTCCTTTACTTTTTGGAAGACTAAATGGACTCTCTTCTGA
CTCTACGATAGATATTCTTTACCAGCTTGGAACAACTCAGGATCCTGGTACAAAAGACAGAATTCAGGCCTTGTTAAAATGGGTTAGTGA
TTCTGCAAGAGTGGCTGCTATGAAGAGAAGTGGCAGGATGAACTACATGTGTCCTAACTCCTCAACAGTAGAGTATGGTCTTCTGATGCC
ATCTCCTTCTCATTTGCACTGTGTAGCAGCCATTCTGTGGCATAGTTATGAGCTGCTTGTAGAATATGACTTACCAGCACTCCTGGACCA
AGAGCTCTTTGAGTTACTTTTTAATTGGTCCATGTCTCTTCCCTGCAATATGGTTTTGAAGAAAGCTGTTGACAGTCTACTTTGCTCAAT
GTGTCACGTACACCCAAACTATTTTTCTTTGCTCATGGGCTGGATGGGAATTACCCCTCCTCCAGTGCAATGTCATCATAGACTGTCCAT
GACAGATGATAGCAAAAAGCAGGATCTTAGTTCATCTTTAACAGATGACTCTAAAAATGCACAAGCACCTCTCGCATTAACTGAATCACA
TTTGGCTACCCTTGCTTCCTCTTCTCAATCTCCTGAAGCTATTAAACAATTACTAGACTCAGGTTTGCCTTCTCTTCTTGTGAGGAGTCT
GGCTAGTTTCTGCTTTAGCCACATTTCTAGCTCAGAAAGCATTGCCCAGTCAATAGATATTTCCCAGGACAAACTCAGGCGCCATCATGT
CCCACAACAATGTAATAAGATGCCTATCACAGCCGACCTAGTTGCTCCTATTCTTAGGTTTTTGACAGAAGTTGGCAATAGCCATATTAT
GAAAGATTGGCTTGGTGGTTCTGAAGTCAATCCACTATGGACAGCACTTCTGTTTTTATTGTGTCACTCTGGGTCCACTTCTGGAAGCCA
TAATTTAGGTGCACAACAGACCAGTGCAAGATCAGCTTCTCTTTCTTCAGCTGCTACAACAGGACTGACTACTCAACAGCGCACAGCAAT
TGAGAATGCAACTGTTGCGTTCTTTCTACAGTGCATTTCATGCCATCCTAATAATCAAAAGCTGATGGCACAGGTTCTTTGTGAACTATT
TCAGACATCTCCTCAAAGAGGGAACCTTCCAACATCTGGGAACATTTCAGGGTTTATACGAAGATTATTTTTACAGTTGATGCTGGAAGA
TGAGAAAGTGACAATGTTTCTTCAGTCTCCATGTCCACTGTACAAAGGTAGAATTAATGCTACTAGCCACGTCATCCAGCATCCAATGTA
TGGAGCAGGCCACAAATTCCGTACTCTTCATTTGCCAGTCTCAACAACATTATCAGATGTTCTTGACAGAGTGTCAGATACTCCAAGTAT
CACAGCTAAATTAATTAGTGAACAAAAAGATGACAAAGAAAAGAAAAACCATGAAGAGAAAGAAAAAGTTAAAGCGGAAAATGGATTTCA
AGACAATTACAGTGTTGTTGTTGCCTCTGGGCTGAAGTCTCAATCTAAACGTGCTGTGTCAGCTACACCACCTCGCCCACCATCCAGGAG
GGGGAGGACAATACCTGATAAAATAGGAAGTACTTCAGGAGCAGAGGCTGCCAACAAAATAATTACTGTCCCAGTGTTTCACCTGTTTCA
CAAACTCTTGGCAGGCCAGCCATTGCCAGCTGAAATGACACTTGCCCAGCTTTTAACTCTCCTATATGACCGAAAACTTCCTCAGGGTTA
CCGCTCAATAGATCTGACTGTTAAATTGGGATCAAGAGTTATAACAGACCCCAGTCTATCAAAAACAGATTCTTATAAAAGACTACACCC
TGAAAAAGATCATGGAGACTTACTTGCTAGCTGTCCAGAAGATGAGGCTCTCACTCCAGGTGATGAATGCATGGATGGGATACTGGATGA
ATCTTTGCTTGAAACCTGTCCAATTCAGTCACCATTACAAGTTTTTGCAGGAATGGGTGGACTGGCTCTTATTGCTGAAAGACTACCCAT
GCTATATCCAGAAGTAATTCAACAGGTGAGTGCTCCAGTTGTAACATCTACCACTCAGGAAAAGCCGAAGGATAGCGATCAGTTTGAATG
GGTGACCATTGAACAGTCAGGGGAGTTAGTTTATGAAGCACCAGAAACTGTTGCGGCTGAACCTCCACCTATCAAGTCAGCAGTACAGAC
CATGTCTCCCATACCTGCCCATTCTTTGGCTGCTTTTGGATTATTTCTTCGTCTTCCGGGCTATGCGGAAGTGCTACTGAAAGAGAGAAA
ACATGCCCAGTGCCTTCTTCGATTGGTATTGGGAGTGACAGATGATGGAGAAGGAAGTCATATTCTTCAATCTCCATCAGCCAATGTGCT
TCCAACCCTTCCTTTCCACGTCCTTCGTAGCTTGTTTAGCACTACACCTTTGACAACTGATGATGGTGTACTTCTAAGGCGGATGGCATT
GGAAATTGGAGCCTTACACCTCATTCTTGTCTGTCTCTCTGCTTTGAGCCACCATTCCCCACGAGTTCCAAACTCTAGCGTGAATCAAAC
TGAGCCACAGGTGTCAAGCTCTCATAACCCTACATCAACAGAAGAACAACAGTTATATTGGGCCAAAGGGACTGGCTTTGGAACAGGCTC
TACAGCTTCTGGGTGGGATGTGGAACAAGCCTTAACTAAGCAAAGGCTGGAAGAGGAACATGTTACCTGCCTTCTGCAGGTTCTTGCCAG
TTACATAAATCCCGTCAGTAGTGCGGTAAATGGAGAAGCTCAGTCATCTCATGAGACTAGAGGGCAGAACAGTAATGCCCTTCCTTCTGT
ACTTCTCGAGCTTCTCAGTCAGTCCTGCCTCATCCCAGCCATGTCATCTTATCTACGAAATGATTCAGTTCTGGACATGGCAAGACATGT
GCCACTCTATCGGGCACTGCTGGAATTGCTTCGGGCCATTGCTTCTTGTGCTGCCATGGTGCCCCTATTGTTGCCCCTTTCTACAGAGAA
CGGTGAAGAGGAAGAAGAACAGTCAGAATGTCAAACTTCTGTTGGTACATTGTTAGCCAAAATGAAGACCTGTGTTGATACCTATACCAA
CCGTTTAAGATCTAAAAGGGAAAATGTTAAAACAGGAGTAAAACCAGATGCGTCTGATCAAGAACCAGAAGGACTTACTCTTTTGGTACC
AGACATCCAAAAGACTGCTGAGATAGTTTATGCAGCCACCACCAGTTTGCGGCAAGCAAATCAGGAAAAAAAACTGGGTGAATACTCCAA
GAAGGCGGCTATGAAACCCAAACCTTTGTCAGTATTAAAGTCACTTGAAGAAAAATATGTGGCTGTTATGAAGAAATTACAGTTTGATAC
GTTTGAAATGGTTTCTGAAGATGAAGATGGGAAATTGGGATTTAAAGTAAATTACCACTACATGTCTCAGGTGAAAAATGCTAATGATGC
GAACAGTGCTGCCAGAGCTCGCCGCCTTGCCCAGGAAGCTGTGACGCTTTCAACCTCACTGCCTCTGTCTTCATCCTCTAGTGTGTTTGT
ACGCTGTGATGAGGAGCGACTTGATATCATGAAGGTTCTAATAACTGGTCCAGCGGACACCCCTTATGCAAATGGCTGCTTTGAGTTTGA
TGTGTATTTTCCTCAAGATTATCCCAGTTCACCCCCTCTTGTGAATCTAGAGACAACTGGTGGTCATAGCGTGCGATTCAATCCAAACCT
TTATAATGATGGCAAGGTTTGTTTAAGCATCTTAAACACGTGGCATGGAAGACCAGAAGAGAAGTGGAATCCTCAGACCTCAAGCTTTTT
GCAAGTGTTGGTGTCTGTCCAGTCCCTTATATTAGTAGCTGAGCCTTATTTTAATGAACCGGGATATGAACGGTCTAGAGGCACTCCCAG
TGGCACACAGAGTTCTCGAGAATATGATGGAAACATTCGACAAGCAACAGTTAAGTGGGCAATGCTAGAACAAATCAGAAACCCTTCACC
ATGTTTTAAAGAGGTAATACACAAACATTTTTACTTGAAAAGAGTTGAGATAATGGCCCAATGTGAGGAGTGGATTGCGGATATCCAGCA
GTACAGCAGTGATAAGCGGGTAGGCAGGACTATGTCTCACCATGCAGCAGCTCTCAAGCGTCACACTGCTCAGCTCCGCGAAGAGTTGCT
GAAACTTCCCTGCCCTGAAGGCTTGGATCCTGACACTGACGATGCCCCAGAGGTGTGCAGAGCCACAACAGGTGCTGAGGAGACTCTAAT
GCATGATCAGGTTAAACCCAGCAGCAGCAAAGAACTCCCCAGTGACTTCCAGTTATGAGCTGCATTGATGTGGACTTCATAGACACAAAG
GCTTCGAAGCACAAGCCAAATATGTCAATATTTGTATGTAAGAAACTAATTATGTAATAGGTAATGAAACTGAAACTATACTATGCCCTT
AAGGAGATCCAGTTTAATTCAAGGTGATCTTTTATTTACCTGTACAGGAGTGTAAACTTTTTTGTGCTTTTATTTTTCAATTGTGAGAAC
CACTGATTGGTATGTTCAACAAATTTGTGTATACAAAGAAATGGATAAATCACTGCTATATAAGGGAAACTACCTTAGGAAAGAATGTTT
ACTGAATGTTTATTTTATTTTATTTTTTTTTTACTATAGAGTGAGGGGTTGTTAACAAAGAATATATATTGGTCATTCTTACAACTACTA
TTTAAAGTCAGCAACTTTTCACTGAATTTGATAGATTTTATGTTTGGCCATATCTTCATGCTCACATTTGATTTCTGAAGACCTCCTACA
TACACTTCAATAAAAGTTAAATGGACATACTCCCTCTTTTTTGATTTACTGGTACATTTTTAAAATAATAAATCTGCCATAAAATGCATT
ATATCTGGAGACTTGCACTTGTATGGATGAATTTATTACATTCAACATATTTAATTTTATGCCTTCTAATTCTAAGATGCAGAAAAAAAT
AAATGAACATGATTTTATTCTATGCCAACATTTGGGCCTCTGAATGTATCTGTTATTTGAATTTAAGTATTTGAAAAGGAATGGTCAATT
TGAAAGTCATTCTAAACTGATTTTTTTTTTCTAAAGGGCTCCTTTTTTCCTGGACTATGTGGTTTTATGACTAAAGTCACATGTATGTAT
TAAACATTGAGGCTCTGTAGAGGAGAGAGGATGTACCTCTCTGGTGCTGTTACAGTACATTCTGTACCTGCCATACAGGCTCATTTTCAT

>66241_66241_5_PLEKHB2-BIRC6_PLEKHB2_chr2_131897848_ENST00000409612_BIRC6_chr2_32715108_ENST00000421745_length(amino acids)=2346AA_BP=187
MVVPGHTGEEMAFVKSGWLLRQSTILKRWKKNWFDLWSDGHLIYYDDQTRQNIEDKVHMPMDCINIRTGQECRDTQPPDGKSKDCMLQIV
CRDGKTISLCAESTDDCLAWKFTLQDSRTNTAYVGSAVMTDETSVVSSPPPYTAYAAPAPEQAYGYGPYGGAYPPGTQVVYAANGQAYAV
PYQYPYAASITSFLTVLAWYPNTLLRTWCLVLHSLTLMTNMQLNSGSSSAIGTQESTAHLLVSDPNLIHVLVKFLSGTSPHGTNQHSPQV
GPTATQAMQEFLTRLQVHLSSTCPQIFSEFLLKLIHILSTERGAFQTGQGPLDAQVKLLEFTLEQNFEVVSVSTISAVIESVTFLVHHYI
TCSDKVMSRSGSDSSVGARACFGGLFANLIRPGDAKAVCGEMTRDQLMFDLLKLVNILVQLPLSGNREYSARVSVTTNTTDSVSDEEKVS
GGKDGNGSSTSVQGSPAYVADLVLANQQIMSQILSALGLCNSSAMAMIIGASGLHLTKHENFHGGLDAISVGDGLFTILTTLSKKASTVH
MMLQPILTYMACGYMGRQGSLATCQLSEPLLWFILRVLDTSDALKAFHDMGGVQLICNNMVTSTRAIVNTARSMVSTIMKFLDSGPNKAV
DSTLKTRILASEPDNAEGIHNFAPLGTITSSSPTAQPAEVLLQATPPHRRARSAAWSYIFLPEEAWCDLTIHLPAAVLLKEIHIQPHLAS
LATCPSSVSVEVSADGVNMLPLSTPVVTSGLTYIKIQLVKAEVASAVCLRLHRPRDASTLGLSQIKLLGLTAFGTTSSATVNNPFLPSED
QVSKTSIGWLRLLHHCLTHISDLEGMMASAAAPTANLLQTCAALLMSPYCGMHSPNIEVVLVKIGLQSTRIGLKLIDILLRNCAASGSDP
TDLNSPLLFGRLNGLSSDSTIDILYQLGTTQDPGTKDRIQALLKWVSDSARVAAMKRSGRMNYMCPNSSTVEYGLLMPSPSHLHCVAAIL
WHSYELLVEYDLPALLDQELFELLFNWSMSLPCNMVLKKAVDSLLCSMCHVHPNYFSLLMGWMGITPPPVQCHHRLSMTDDSKKQDLSSS
LTDDSKNAQAPLALTESHLATLASSSQSPEAIKQLLDSGLPSLLVRSLASFCFSHISSSESIAQSIDISQDKLRRHHVPQQCNKMPITAD
LVAPILRFLTEVGNSHIMKDWLGGSEVNPLWTALLFLLCHSGSTSGSHNLGAQQTSARSASLSSAATTGLTTQQRTAIENATVAFFLQCI
SCHPNNQKLMAQVLCELFQTSPQRGNLPTSGNISGFIRRLFLQLMLEDEKVTMFLQSPCPLYKGRINATSHVIQHPMYGAGHKFRTLHLP
VSTTLSDVLDRVSDTPSITAKLISEQKDDKEKKNHEEKEKVKAENGFQDNYSVVVASGLKSQSKRAVSATPPRPPSRRGRTIPDKIGSTS
GAEAANKIITVPVFHLFHKLLAGQPLPAEMTLAQLLTLLYDRKLPQGYRSIDLTVKLGSRVITDPSLSKTDSYKRLHPEKDHGDLLASCP
EDEALTPGDECMDGILDESLLETCPIQSPLQVFAGMGGLALIAERLPMLYPEVIQQVSAPVVTSTTQEKPKDSDQFEWVTIEQSGELVYE
APETVAAEPPPIKSAVQTMSPIPAHSLAAFGLFLRLPGYAEVLLKERKHAQCLLRLVLGVTDDGEGSHILQSPSANVLPTLPFHVLRSLF
STTPLTTDDGVLLRRMALEIGALHLILVCLSALSHHSPRVPNSSVNQTEPQVSSSHNPTSTEEQQLYWAKGTGFGTGSTASGWDVEQALT
KQRLEEEHVTCLLQVLASYINPVSSAVNGEAQSSHETRGQNSNALPSVLLELLSQSCLIPAMSSYLRNDSVLDMARHVPLYRALLELLRA
IASCAAMVPLLLPLSTENGEEEEEQSECQTSVGTLLAKMKTCVDTYTNRLRSKRENVKTGVKPDASDQEPEGLTLLVPDIQKTAEIVYAA
TTSLRQANQEKKLGEYSKKAAMKPKPLSVLKSLEEKYVAVMKKLQFDTFEMVSEDEDGKLGFKVNYHYMSQVKNANDANSAARARRLAQE
AVTLSTSLPLSSSSSVFVRCDEERLDIMKVLITGPADTPYANGCFEFDVYFPQDYPSSPPLVNLETTGGHSVRFNPNLYNDGKVCLSILN
TWHGRPEEKWNPQTSSFLQVLVSVQSLILVAEPYFNEPGYERSRGTPSGTQSSREYDGNIRQATVKWAMLEQIRNPSPCFKEVIHKHFYL
KRVEIMAQCEEWIADIQQYSSDKRVGRTMSHHAAALKRHTAQLREELLKLPCPEGLDPDTDDAPEVCRATTGAEETLMHDQVKPSSSKEL

--------------------------------------------------------------
>66241_66241_6_PLEKHB2-BIRC6_PLEKHB2_chr2_131897848_ENST00000538982_BIRC6_chr2_32715108_ENST00000421745_length(transcript)=8030nt_BP=556nt
TTGCAGGCGAGCAGGCGAGGAATCGCCGTGGCGTCTTGGTGTTCTCCACGCTGGTTCGCAGGTACTATTTTGAAGCGCTGGAAGAAGAAC
TGGTTTGATCTGTGGTCGGATGGTCACCTGATCTATTATGATGACCAGACTCGGCAGAATATCGAGGATAAGGTCCACATGCCAATGGAC
TGCATCAACATCCGCACGGGGCAGGAATGTCGGGATACTCAGCCCCCGGATGGAAAGTCAAAAGACTGCATGCTCCAGATTGTTTGTCGA
GATGGGAAAACAATTAGTCTTTGTGCAGAAAGCACAGATGATTGCTTGGCCTGGAAATTTACACTCCAAGATTCTAGGACAAACACAGCG
TATGTGGGCTCTGCAGTCATGACCGATGAGACATCCGTGGTTTCCTCACCTCCACCATACACGGCCTATGCTGCACCGGCCCCTGAGCAG
GCTTATGGCTATGGGCCATACGGTGGTGCGTACCCGCCAGGAACTCAAGTTGTCTACGCTGCGAATGGGCAGGCGTATGCCGTGCCCTAC
CAGTACCCATATGCAGCATCAATAACTAGCTTTCTCACAGTGTTAGCTTGGTATCCCAATACTTTGCTCCGGACATGGTGCCTTGTGCTT
CATAGCCTAACACTCATGACAAACATGCAGCTTAATTCTGGTTCCAGCAGTGCCATTGGAACTCAGGAGAGTACTGCTCATTTGTTGGTT
TCAGATCCAAACCTAATTCATGTATTAGTGAAATTTCTTTCTGGCACCAGTCCACATGGAACAAATCAACACAGTCCACAGGTTGGTCCT
ACAGCTACACAAGCTATGCAAGAATTTCTTACTCGATTACAAGTGCATCTTTCTTCAACATGTCCTCAGATATTCAGTGAATTTTTGCTC
AAGCTAATTCATATACTTTCAACTGAAAGGGGTGCTTTCCAGACAGGCCAAGGACCTCTCGATGCCCAAGTGAAGCTCTTAGAATTCACT
CTGGAGCAGAATTTTGAAGTCGTTTCAGTTAGTACTATTTCTGCCGTGATAGAATCGGTTACATTTTTAGTGCACCACTATATCACTTGC
TCAGACAAAGTAATGTCAAGAAGTGGATCAGATAGCTCCGTGGGTGCTCGAGCATGCTTTGGGGGACTCTTTGCCAATCTTATTCGTCCG
GGTGATGCAAAAGCAGTTTGTGGCGAAATGACAAGAGATCAACTCATGTTTGATTTGTTAAAACTTGTTAACATTTTAGTGCAGCTGCCT
CTTTCAGGCAATAGGGAATACAGTGCAAGAGTGTCTGTGACCACAAATACAACAGATAGTGTTTCAGATGAAGAAAAAGTCTCAGGAGGC
AAAGATGGCAATGGAAGCAGTACCAGTGTTCAAGGATCGCCTGCATATGTTGCTGACTTAGTCTTAGCCAACCAACAAATTATGAGCCAG
ATTTTGTCTGCTCTGGGCCTGTGTAATAGCAGTGCCATGGCAATGATAATTGGAGCAAGTGGATTACATCTCACTAAACATGAAAACTTT
CATGGTGGGTTGGATGCCATATCAGTTGGGGATGGATTATTTACCATACTGACAACCCTTAGTAAAAAAGCTTCTACAGTCCACATGATG
CTGCAGCCAATTTTAACATACATGGCCTGTGGATATATGGGCAGACAAGGCTCTCTTGCTACTTGCCAGTTATCTGAGCCATTATTGTGG
TTCATTTTGAGAGTATTGGATACTAGTGATGCCTTGAAAGCATTTCATGATATGGGTGGTGTTCAGCTCATATGCAATAATATGGTTACT
AGTACAAGGGCTATTGTGAACACTGCAAGAAGTATGGTATCAACTATTATGAAATTTCTTGACTCTGGTCCAAATAAAGCTGTTGACAGC
ACATTGAAAACAAGAATACTAGCTTCTGAGCCTGACAATGCTGAAGGGATTCATAACTTTGCACCCCTCGGTACAATCACATCTAGCAGT
CCTACTGCCCAACCAGCTGAAGTGCTATTGCAGGCCACACCTCCTCACAGAAGAGCTCGCTCTGCTGCTTGGTCCTACATCTTTCTTCCA
GAGGAGGCTTGGTGTGACCTTACCATTCACCTTCCTGCAGCAGTGCTGCTTAAGGAGATACATATCCAGCCTCATCTTGCATCTCTTGCA
ACCTGCCCTTCCTCAGTGTCTGTTGAAGTAAGTGCAGATGGGGTAAATATGCTACCTTTGTCCACTCCTGTTGTCACAAGTGGCCTCACC
TACATAAAAATTCAGCTTGTAAAAGCCGAAGTAGCTTCTGCTGTCTGCCTTAGACTACATCGTCCACGGGATGCCAGCACATTAGGCCTT
TCACAAATTAAATTATTGGGGCTCACTGCTTTTGGTACCACCTCTTCTGCAACAGTTAATAATCCATTCCTTCCATCTGAAGATCAGGTA
TCCAAAACAAGTATTGGATGGTTACGGTTATTACATCATTGCCTTACTCACATAAGTGATCTAGAAGGAATGATGGCAAGTGCAGCTGCA
CCTACTGCTAATCTGCTGCAGACTTGTGCGGCCTTATTGATGTCACCTTACTGTGGAATGCATTCACCCAACATCGAGGTTGTGCTTGTA
AAGATAGGACTGCAGTCTACTAGAATTGGCCTGAAGCTCATAGACATTCTCCTGAGAAATTGTGCAGCATCAGGCAGTGATCCTACAGAT
TTGAATAGTCCTTTACTTTTTGGAAGACTAAATGGACTCTCTTCTGACTCTACGATAGATATTCTTTACCAGCTTGGAACAACTCAGGAT
CCTGGTACAAAAGACAGAATTCAGGCCTTGTTAAAATGGGTTAGTGATTCTGCAAGAGTGGCTGCTATGAAGAGAAGTGGCAGGATGAAC
TACATGTGTCCTAACTCCTCAACAGTAGAGTATGGTCTTCTGATGCCATCTCCTTCTCATTTGCACTGTGTAGCAGCCATTCTGTGGCAT
AGTTATGAGCTGCTTGTAGAATATGACTTACCAGCACTCCTGGACCAAGAGCTCTTTGAGTTACTTTTTAATTGGTCCATGTCTCTTCCC
TGCAATATGGTTTTGAAGAAAGCTGTTGACAGTCTACTTTGCTCAATGTGTCACGTACACCCAAACTATTTTTCTTTGCTCATGGGCTGG
ATGGGAATTACCCCTCCTCCAGTGCAATGTCATCATAGACTGTCCATGACAGATGATAGCAAAAAGCAGGATCTTAGTTCATCTTTAACA
GATGACTCTAAAAATGCACAAGCACCTCTCGCATTAACTGAATCACATTTGGCTACCCTTGCTTCCTCTTCTCAATCTCCTGAAGCTATT
AAACAATTACTAGACTCAGGTTTGCCTTCTCTTCTTGTGAGGAGTCTGGCTAGTTTCTGCTTTAGCCACATTTCTAGCTCAGAAAGCATT
GCCCAGTCAATAGATATTTCCCAGGACAAACTCAGGCGCCATCATGTCCCACAACAATGTAATAAGATGCCTATCACAGCCGACCTAGTT
GCTCCTATTCTTAGGTTTTTGACAGAAGTTGGCAATAGCCATATTATGAAAGATTGGCTTGGTGGTTCTGAAGTCAATCCACTATGGACA
GCACTTCTGTTTTTATTGTGTCACTCTGGGTCCACTTCTGGAAGCCATAATTTAGGTGCACAACAGACCAGTGCAAGATCAGCTTCTCTT
TCTTCAGCTGCTACAACAGGACTGACTACTCAACAGCGCACAGCAATTGAGAATGCAACTGTTGCGTTCTTTCTACAGTGCATTTCATGC
CATCCTAATAATCAAAAGCTGATGGCACAGGTTCTTTGTGAACTATTTCAGACATCTCCTCAAAGAGGGAACCTTCCAACATCTGGGAAC
ATTTCAGGGTTTATACGAAGATTATTTTTACAGTTGATGCTGGAAGATGAGAAAGTGACAATGTTTCTTCAGTCTCCATGTCCACTGTAC
AAAGGTAGAATTAATGCTACTAGCCACGTCATCCAGCATCCAATGTATGGAGCAGGCCACAAATTCCGTACTCTTCATTTGCCAGTCTCA
ACAACATTATCAGATGTTCTTGACAGAGTGTCAGATACTCCAAGTATCACAGCTAAATTAATTAGTGAACAAAAAGATGACAAAGAAAAG
AAAAACCATGAAGAGAAAGAAAAAGTTAAAGCGGAAAATGGATTTCAAGACAATTACAGTGTTGTTGTTGCCTCTGGGCTGAAGTCTCAA
TCTAAACGTGCTGTGTCAGCTACACCACCTCGCCCACCATCCAGGAGGGGGAGGACAATACCTGATAAAATAGGAAGTACTTCAGGAGCA
GAGGCTGCCAACAAAATAATTACTGTCCCAGTGTTTCACCTGTTTCACAAACTCTTGGCAGGCCAGCCATTGCCAGCTGAAATGACACTT
GCCCAGCTTTTAACTCTCCTATATGACCGAAAACTTCCTCAGGGTTACCGCTCAATAGATCTGACTGTTAAATTGGGATCAAGAGTTATA
ACAGACCCCAGTCTATCAAAAACAGATTCTTATAAAAGACTACACCCTGAAAAAGATCATGGAGACTTACTTGCTAGCTGTCCAGAAGAT
GAGGCTCTCACTCCAGGTGATGAATGCATGGATGGGATACTGGATGAATCTTTGCTTGAAACCTGTCCAATTCAGTCACCATTACAAGTT
TTTGCAGGAATGGGTGGACTGGCTCTTATTGCTGAAAGACTACCCATGCTATATCCAGAAGTAATTCAACAGGTGAGTGCTCCAGTTGTA
ACATCTACCACTCAGGAAAAGCCGAAGGATAGCGATCAGTTTGAATGGGTGACCATTGAACAGTCAGGGGAGTTAGTTTATGAAGCACCA
GAAACTGTTGCGGCTGAACCTCCACCTATCAAGTCAGCAGTACAGACCATGTCTCCCATACCTGCCCATTCTTTGGCTGCTTTTGGATTA
TTTCTTCGTCTTCCGGGCTATGCGGAAGTGCTACTGAAAGAGAGAAAACATGCCCAGTGCCTTCTTCGATTGGTATTGGGAGTGACAGAT
GATGGAGAAGGAAGTCATATTCTTCAATCTCCATCAGCCAATGTGCTTCCAACCCTTCCTTTCCACGTCCTTCGTAGCTTGTTTAGCACT
ACACCTTTGACAACTGATGATGGTGTACTTCTAAGGCGGATGGCATTGGAAATTGGAGCCTTACACCTCATTCTTGTCTGTCTCTCTGCT
TTGAGCCACCATTCCCCACGAGTTCCAAACTCTAGCGTGAATCAAACTGAGCCACAGGTGTCAAGCTCTCATAACCCTACATCAACAGAA
GAACAACAGTTATATTGGGCCAAAGGGACTGGCTTTGGAACAGGCTCTACAGCTTCTGGGTGGGATGTGGAACAAGCCTTAACTAAGCAA
AGGCTGGAAGAGGAACATGTTACCTGCCTTCTGCAGGTTCTTGCCAGTTACATAAATCCCGTCAGTAGTGCGGTAAATGGAGAAGCTCAG
TCATCTCATGAGACTAGAGGGCAGAACAGTAATGCCCTTCCTTCTGTACTTCTCGAGCTTCTCAGTCAGTCCTGCCTCATCCCAGCCATG
TCATCTTATCTACGAAATGATTCAGTTCTGGACATGGCAAGACATGTGCCACTCTATCGGGCACTGCTGGAATTGCTTCGGGCCATTGCT
TCTTGTGCTGCCATGGTGCCCCTATTGTTGCCCCTTTCTACAGAGAACGGTGAAGAGGAAGAAGAACAGTCAGAATGTCAAACTTCTGTT
GGTACATTGTTAGCCAAAATGAAGACCTGTGTTGATACCTATACCAACCGTTTAAGATCTAAAAGGGAAAATGTTAAAACAGGAGTAAAA
CCAGATGCGTCTGATCAAGAACCAGAAGGACTTACTCTTTTGGTACCAGACATCCAAAAGACTGCTGAGATAGTTTATGCAGCCACCACC
AGTTTGCGGCAAGCAAATCAGGAAAAAAAACTGGGTGAATACTCCAAGAAGGCGGCTATGAAACCCAAACCTTTGTCAGTATTAAAGTCA
CTTGAAGAAAAATATGTGGCTGTTATGAAGAAATTACAGTTTGATACGTTTGAAATGGTTTCTGAAGATGAAGATGGGAAATTGGGATTT
AAAGTAAATTACCACTACATGTCTCAGGTGAAAAATGCTAATGATGCGAACAGTGCTGCCAGAGCTCGCCGCCTTGCCCAGGAAGCTGTG
ACGCTTTCAACCTCACTGCCTCTGTCTTCATCCTCTAGTGTGTTTGTACGCTGTGATGAGGAGCGACTTGATATCATGAAGGTTCTAATA
ACTGGTCCAGCGGACACCCCTTATGCAAATGGCTGCTTTGAGTTTGATGTGTATTTTCCTCAAGATTATCCCAGTTCACCCCCTCTTGTG
AATCTAGAGACAACTGGTGGTCATAGCGTGCGATTCAATCCAAACCTTTATAATGATGGCAAGGTTTGTTTAAGCATCTTAAACACGTGG
CATGGAAGACCAGAAGAGAAGTGGAATCCTCAGACCTCAAGCTTTTTGCAAGTGTTGGTGTCTGTCCAGTCCCTTATATTAGTAGCTGAG
CCTTATTTTAATGAACCGGGATATGAACGGTCTAGAGGCACTCCCAGTGGCACACAGAGTTCTCGAGAATATGATGGAAACATTCGACAA
GCAACAGTTAAGTGGGCAATGCTAGAACAAATCAGAAACCCTTCACCATGTTTTAAAGAGGTAATACACAAACATTTTTACTTGAAAAGA
GTTGAGATAATGGCCCAATGTGAGGAGTGGATTGCGGATATCCAGCAGTACAGCAGTGATAAGCGGGTAGGCAGGACTATGTCTCACCAT
GCAGCAGCTCTCAAGCGTCACACTGCTCAGCTCCGCGAAGAGTTGCTGAAACTTCCCTGCCCTGAAGGCTTGGATCCTGACACTGACGAT
GCCCCAGAGGTGTGCAGAGCCACAACAGGTGCTGAGGAGACTCTAATGCATGATCAGGTTAAACCCAGCAGCAGCAAAGAACTCCCCAGT
GACTTCCAGTTATGAGCTGCATTGATGTGGACTTCATAGACACAAAGGCTTCGAAGCACAAGCCAAATATGTCAATATTTGTATGTAAGA
AACTAATTATGTAATAGGTAATGAAACTGAAACTATACTATGCCCTTAAGGAGATCCAGTTTAATTCAAGGTGATCTTTTATTTACCTGT
ACAGGAGTGTAAACTTTTTTGTGCTTTTATTTTTCAATTGTGAGAACCACTGATTGGTATGTTCAACAAATTTGTGTATACAAAGAAATG
GATAAATCACTGCTATATAAGGGAAACTACCTTAGGAAAGAATGTTTACTGAATGTTTATTTTATTTTATTTTTTTTTTACTATAGAGTG
AGGGGTTGTTAACAAAGAATATATATTGGTCATTCTTACAACTACTATTTAAAGTCAGCAACTTTTCACTGAATTTGATAGATTTTATGT
TTGGCCATATCTTCATGCTCACATTTGATTTCTGAAGACCTCCTACATACACTTCAATAAAAGTTAAATGGACATACTCCCTCTTTTTTG
ATTTACTGGTACATTTTTAAAATAATAAATCTGCCATAAAATGCATTATATCTGGAGACTTGCACTTGTATGGATGAATTTATTACATTC
AACATATTTAATTTTATGCCTTCTAATTCTAAGATGCAGAAAAAAATAAATGAACATGATTTTATTCTATGCCAACATTTGGGCCTCTGA
ATGTATCTGTTATTTGAATTTAAGTATTTGAAAAGGAATGGTCAATTTGAAAGTCATTCTAAACTGATTTTTTTTTTCTAAAGGGCTCCT
TTTTTCCTGGACTATGTGGTTTTATGACTAAAGTCACATGTATGTATTAAACATTGAGGCTCTGTAGAGGAGAGAGGATGTACCTCTCTG
GTGCTGTTACAGTACATTCTGTACCTGCCATACAGGCTCATTTTCATGCAAATTCTTCCTAGAGCCAAATAAATAAAGACTTAGGTGAAT

>66241_66241_6_PLEKHB2-BIRC6_PLEKHB2_chr2_131897848_ENST00000538982_BIRC6_chr2_32715108_ENST00000421745_length(amino acids)=2344AA_BP=185
LQASRRGIAVASWCSPRWFAGTILKRWKKNWFDLWSDGHLIYYDDQTRQNIEDKVHMPMDCINIRTGQECRDTQPPDGKSKDCMLQIVCR
DGKTISLCAESTDDCLAWKFTLQDSRTNTAYVGSAVMTDETSVVSSPPPYTAYAAPAPEQAYGYGPYGGAYPPGTQVVYAANGQAYAVPY
QYPYAASITSFLTVLAWYPNTLLRTWCLVLHSLTLMTNMQLNSGSSSAIGTQESTAHLLVSDPNLIHVLVKFLSGTSPHGTNQHSPQVGP
TATQAMQEFLTRLQVHLSSTCPQIFSEFLLKLIHILSTERGAFQTGQGPLDAQVKLLEFTLEQNFEVVSVSTISAVIESVTFLVHHYITC
SDKVMSRSGSDSSVGARACFGGLFANLIRPGDAKAVCGEMTRDQLMFDLLKLVNILVQLPLSGNREYSARVSVTTNTTDSVSDEEKVSGG
KDGNGSSTSVQGSPAYVADLVLANQQIMSQILSALGLCNSSAMAMIIGASGLHLTKHENFHGGLDAISVGDGLFTILTTLSKKASTVHMM
LQPILTYMACGYMGRQGSLATCQLSEPLLWFILRVLDTSDALKAFHDMGGVQLICNNMVTSTRAIVNTARSMVSTIMKFLDSGPNKAVDS
TLKTRILASEPDNAEGIHNFAPLGTITSSSPTAQPAEVLLQATPPHRRARSAAWSYIFLPEEAWCDLTIHLPAAVLLKEIHIQPHLASLA
TCPSSVSVEVSADGVNMLPLSTPVVTSGLTYIKIQLVKAEVASAVCLRLHRPRDASTLGLSQIKLLGLTAFGTTSSATVNNPFLPSEDQV
SKTSIGWLRLLHHCLTHISDLEGMMASAAAPTANLLQTCAALLMSPYCGMHSPNIEVVLVKIGLQSTRIGLKLIDILLRNCAASGSDPTD
LNSPLLFGRLNGLSSDSTIDILYQLGTTQDPGTKDRIQALLKWVSDSARVAAMKRSGRMNYMCPNSSTVEYGLLMPSPSHLHCVAAILWH
SYELLVEYDLPALLDQELFELLFNWSMSLPCNMVLKKAVDSLLCSMCHVHPNYFSLLMGWMGITPPPVQCHHRLSMTDDSKKQDLSSSLT
DDSKNAQAPLALTESHLATLASSSQSPEAIKQLLDSGLPSLLVRSLASFCFSHISSSESIAQSIDISQDKLRRHHVPQQCNKMPITADLV
APILRFLTEVGNSHIMKDWLGGSEVNPLWTALLFLLCHSGSTSGSHNLGAQQTSARSASLSSAATTGLTTQQRTAIENATVAFFLQCISC
HPNNQKLMAQVLCELFQTSPQRGNLPTSGNISGFIRRLFLQLMLEDEKVTMFLQSPCPLYKGRINATSHVIQHPMYGAGHKFRTLHLPVS
TTLSDVLDRVSDTPSITAKLISEQKDDKEKKNHEEKEKVKAENGFQDNYSVVVASGLKSQSKRAVSATPPRPPSRRGRTIPDKIGSTSGA
EAANKIITVPVFHLFHKLLAGQPLPAEMTLAQLLTLLYDRKLPQGYRSIDLTVKLGSRVITDPSLSKTDSYKRLHPEKDHGDLLASCPED
EALTPGDECMDGILDESLLETCPIQSPLQVFAGMGGLALIAERLPMLYPEVIQQVSAPVVTSTTQEKPKDSDQFEWVTIEQSGELVYEAP
ETVAAEPPPIKSAVQTMSPIPAHSLAAFGLFLRLPGYAEVLLKERKHAQCLLRLVLGVTDDGEGSHILQSPSANVLPTLPFHVLRSLFST
TPLTTDDGVLLRRMALEIGALHLILVCLSALSHHSPRVPNSSVNQTEPQVSSSHNPTSTEEQQLYWAKGTGFGTGSTASGWDVEQALTKQ
RLEEEHVTCLLQVLASYINPVSSAVNGEAQSSHETRGQNSNALPSVLLELLSQSCLIPAMSSYLRNDSVLDMARHVPLYRALLELLRAIA
SCAAMVPLLLPLSTENGEEEEEQSECQTSVGTLLAKMKTCVDTYTNRLRSKRENVKTGVKPDASDQEPEGLTLLVPDIQKTAEIVYAATT
SLRQANQEKKLGEYSKKAAMKPKPLSVLKSLEEKYVAVMKKLQFDTFEMVSEDEDGKLGFKVNYHYMSQVKNANDANSAARARRLAQEAV
TLSTSLPLSSSSSVFVRCDEERLDIMKVLITGPADTPYANGCFEFDVYFPQDYPSSPPLVNLETTGGHSVRFNPNLYNDGKVCLSILNTW
HGRPEEKWNPQTSSFLQVLVSVQSLILVAEPYFNEPGYERSRGTPSGTQSSREYDGNIRQATVKWAMLEQIRNPSPCFKEVIHKHFYLKR
VEIMAQCEEWIADIQQYSSDKRVGRTMSHHAAALKRHTAQLREELLKLPCPEGLDPDTDDAPEVCRATTGAEETLMHDQVKPSSSKELPS

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Fusion Gene PPI Analysis for PLEKHB2-BIRC6


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for PLEKHB2-BIRC6


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for PLEKHB2-BIRC6


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneC0006826Malignant Neoplasms1CTD_human
TgeneC0027651Neoplasms1CTD_human
TgeneC0086692Benign Neoplasm1CTD_human