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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ANO1-SLC7A8 (FusionGDB2 ID:HG55107TG23428)

Fusion Gene Summary for ANO1-SLC7A8

check button Fusion gene summary
Fusion gene informationFusion gene name: ANO1-SLC7A8
Fusion gene ID: hg55107tg23428
HgeneTgene
Gene symbol

ANO1

SLC7A8

Gene ID

55107

23428

Gene nameanoctamin 1solute carrier family 7 member 8
SynonymsDOG1|ORAOV2|TAOS2|TMEM16ALAT2|LPI-PC1
Cytomap('ANO1')('SLC7A8')

11q13.3

14q11.2

Type of geneprotein-codingprotein-coding
Descriptionanoctamin-1Ca2+-activated Cl- channelanoctamin 1, calcium activated chloride channelcalcium activated chloride channeldiscovered on gastrointestinal stromal tumors protein 1oral cancer overexpressed 2transmembrane protein 16A (eight membrane-spanninlarge neutral amino acids transporter small subunit 2L-type amino acid transporter 2integral membrane protein E16Hsolute carrier family 7 (amino acid transporter light chain, L system), member 8solute carrier family 7 (amino acid transporter, L-type),
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000525494, ENST00000355303, 
ENST00000398543, ENST00000530676, 
ENST00000531349, ENST00000538023, 
ENST00000316296, 
Fusion gene scores* DoF score20 X 18 X 9=32404 X 4 X 4=64
# samples 204
** MAII scorelog2(20/3240*10)=-4.01792190799726
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(4/64*10)=-0.678071905112638
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ANO1 [Title/Abstract] AND SLC7A8 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointANO1(70017145)-SLC7A8(23635749), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneANO1

GO:0006812

cation transport

22946059

TgeneSLC7A8

GO:0006865

amino acid transport

10391915|10574970|15918515


check buttonFusion gene breakpoints across ANO1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across SLC7A8 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUSCTCGA-68-A59J-01AANO1chr11

70017145

-SLC7A8chr14

23635749

-
ChimerDB4LUSCTCGA-68-A59J-01AANO1chr11

70017145

+SLC7A8chr14

23635749

-
ChimerDB4LUSCTCGA-68-A59JANO1chr11

70017145

+SLC7A8chr14

23635749

-


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Fusion Gene ORF analysis for ANO1-SLC7A8

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000525494ENST00000316902ANO1chr11

70017145

+SLC7A8chr14

23635749

-
3UTR-3CDSENST00000525494ENST00000469263ANO1chr11

70017145

+SLC7A8chr14

23635749

-
3UTR-intronENST00000525494ENST00000422941ANO1chr11

70017145

+SLC7A8chr14

23635749

-
3UTR-intronENST00000525494ENST00000453702ANO1chr11

70017145

+SLC7A8chr14

23635749

-
3UTR-intronENST00000525494ENST00000529705ANO1chr11

70017145

+SLC7A8chr14

23635749

-
3UTR-intronENST00000525494ENST00000532568ANO1chr11

70017145

+SLC7A8chr14

23635749

-
5CDS-intronENST00000355303ENST00000422941ANO1chr11

70017145

+SLC7A8chr14

23635749

-
5CDS-intronENST00000355303ENST00000453702ANO1chr11

70017145

+SLC7A8chr14

23635749

-
5CDS-intronENST00000355303ENST00000529705ANO1chr11

70017145

+SLC7A8chr14

23635749

-
5CDS-intronENST00000355303ENST00000532568ANO1chr11

70017145

+SLC7A8chr14

23635749

-
5CDS-intronENST00000398543ENST00000422941ANO1chr11

70017145

+SLC7A8chr14

23635749

-
5CDS-intronENST00000398543ENST00000453702ANO1chr11

70017145

+SLC7A8chr14

23635749

-
5CDS-intronENST00000398543ENST00000529705ANO1chr11

70017145

+SLC7A8chr14

23635749

-
5CDS-intronENST00000398543ENST00000532568ANO1chr11

70017145

+SLC7A8chr14

23635749

-
5CDS-intronENST00000530676ENST00000422941ANO1chr11

70017145

+SLC7A8chr14

23635749

-
5CDS-intronENST00000530676ENST00000453702ANO1chr11

70017145

+SLC7A8chr14

23635749

-
5CDS-intronENST00000530676ENST00000529705ANO1chr11

70017145

+SLC7A8chr14

23635749

-
5CDS-intronENST00000530676ENST00000532568ANO1chr11

70017145

+SLC7A8chr14

23635749

-
5CDS-intronENST00000531349ENST00000422941ANO1chr11

70017145

+SLC7A8chr14

23635749

-
5CDS-intronENST00000531349ENST00000453702ANO1chr11

70017145

+SLC7A8chr14

23635749

-
5CDS-intronENST00000531349ENST00000529705ANO1chr11

70017145

+SLC7A8chr14

23635749

-
5CDS-intronENST00000531349ENST00000532568ANO1chr11

70017145

+SLC7A8chr14

23635749

-
5CDS-intronENST00000538023ENST00000422941ANO1chr11

70017145

+SLC7A8chr14

23635749

-
5CDS-intronENST00000538023ENST00000453702ANO1chr11

70017145

+SLC7A8chr14

23635749

-
5CDS-intronENST00000538023ENST00000529705ANO1chr11

70017145

+SLC7A8chr14

23635749

-
5CDS-intronENST00000538023ENST00000532568ANO1chr11

70017145

+SLC7A8chr14

23635749

-
In-frameENST00000355303ENST00000316902ANO1chr11

70017145

+SLC7A8chr14

23635749

-
In-frameENST00000355303ENST00000469263ANO1chr11

70017145

+SLC7A8chr14

23635749

-
In-frameENST00000398543ENST00000316902ANO1chr11

70017145

+SLC7A8chr14

23635749

-
In-frameENST00000398543ENST00000469263ANO1chr11

70017145

+SLC7A8chr14

23635749

-
In-frameENST00000530676ENST00000316902ANO1chr11

70017145

+SLC7A8chr14

23635749

-
In-frameENST00000530676ENST00000469263ANO1chr11

70017145

+SLC7A8chr14

23635749

-
In-frameENST00000531349ENST00000316902ANO1chr11

70017145

+SLC7A8chr14

23635749

-
In-frameENST00000531349ENST00000469263ANO1chr11

70017145

+SLC7A8chr14

23635749

-
In-frameENST00000538023ENST00000316902ANO1chr11

70017145

+SLC7A8chr14

23635749

-
In-frameENST00000538023ENST00000469263ANO1chr11

70017145

+SLC7A8chr14

23635749

-
intron-3CDSENST00000316296ENST00000316902ANO1chr11

70017145

+SLC7A8chr14

23635749

-
intron-3CDSENST00000316296ENST00000469263ANO1chr11

70017145

+SLC7A8chr14

23635749

-
intron-intronENST00000316296ENST00000422941ANO1chr11

70017145

+SLC7A8chr14

23635749

-
intron-intronENST00000316296ENST00000453702ANO1chr11

70017145

+SLC7A8chr14

23635749

-
intron-intronENST00000316296ENST00000529705ANO1chr11

70017145

+SLC7A8chr14

23635749

-
intron-intronENST00000316296ENST00000532568ANO1chr11

70017145

+SLC7A8chr14

23635749

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000355303ANO1chr1170017145+ENST00000316902SLC7A8chr1423635749-5994265522141111296
ENST00000355303ANO1chr1170017145+ENST00000469263SLC7A8chr1423635749-5334265522133731050
ENST00000398543ANO1chr1170017145+ENST00000316902SLC7A8chr1423635749-564823094937651238
ENST00000398543ANO1chr1170017145+ENST00000469263SLC7A8chr1423635749-49882309493027992
ENST00000538023ANO1chr1170017145+ENST00000316902SLC7A8chr1423635749-573823994938551268
ENST00000538023ANO1chr1170017145+ENST00000469263SLC7A8chr1423635749-507823994931171022
ENST00000530676ANO1chr1170017145+ENST00000316902SLC7A8chr1423635749-5740240124938571202
ENST00000530676ANO1chr1170017145+ENST00000469263SLC7A8chr1423635749-508024012493119956
ENST00000531349ANO1chr1170017145+ENST00000316902SLC7A8chr1423635749-503216931803149989
ENST00000531349ANO1chr1170017145+ENST00000469263SLC7A8chr1423635749-437216931802411743

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000355303ENST00000316902ANO1chr1170017145+SLC7A8chr1423635749-0.0005801310.9994199
ENST00000355303ENST00000469263ANO1chr1170017145+SLC7A8chr1423635749-0.0019102420.99808973
ENST00000398543ENST00000316902ANO1chr1170017145+SLC7A8chr1423635749-0.0007231770.9992768
ENST00000398543ENST00000469263ANO1chr1170017145+SLC7A8chr1423635749-0.000615430.9993845
ENST00000538023ENST00000316902ANO1chr1170017145+SLC7A8chr1423635749-0.0003707890.99962914
ENST00000538023ENST00000469263ANO1chr1170017145+SLC7A8chr1423635749-0.0012859250.9987141
ENST00000530676ENST00000316902ANO1chr1170017145+SLC7A8chr1423635749-0.0012347780.99876523
ENST00000530676ENST00000469263ANO1chr1170017145+SLC7A8chr1423635749-0.0023080790.997692
ENST00000531349ENST00000316902ANO1chr1170017145+SLC7A8chr1423635749-0.0005097560.99949026
ENST00000531349ENST00000469263ANO1chr1170017145+SLC7A8chr1423635749-0.0017479850.998252

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Fusion Genomic Features for ANO1-SLC7A8


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for ANO1-SLC7A8


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr11:70017145/chr14:23635749)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneANO1chr11:70017145chr14:23635749ENST00000355303+22261_333783987.0Topological domainCytoplasmic
HgeneANO1chr11:70017145chr14:23635749ENST00000355303+2226355_406783987.0Topological domainExtracellular
HgeneANO1chr11:70017145chr14:23635749ENST00000355303+2226428_519783987.0Topological domainCytoplasmic
HgeneANO1chr11:70017145chr14:23635749ENST00000355303+2226541_568783987.0Topological domainExtracellular
HgeneANO1chr11:70017145chr14:23635749ENST00000355303+2226590_607783987.0Topological domainCytoplasmic
HgeneANO1chr11:70017145chr14:23635749ENST00000355303+2226629_657783987.0Topological domainExtracellular
HgeneANO1chr11:70017145chr14:23635749ENST00000355303+2226679_725783987.0Topological domainCytoplasmic
HgeneANO1chr11:70017145chr14:23635749ENST00000355303+2226768_784783987.0Topological domainCytoplasmic
HgeneANO1chr11:70017145chr14:23635749ENST00000398543+20241_333637841.0Topological domainCytoplasmic
HgeneANO1chr11:70017145chr14:23635749ENST00000398543+2024355_406637841.0Topological domainExtracellular
HgeneANO1chr11:70017145chr14:23635749ENST00000398543+2024428_519637841.0Topological domainCytoplasmic
HgeneANO1chr11:70017145chr14:23635749ENST00000398543+2024541_568637841.0Topological domainExtracellular
HgeneANO1chr11:70017145chr14:23635749ENST00000398543+2024590_607637841.0Topological domainCytoplasmic
HgeneANO1chr11:70017145chr14:23635749ENST00000530676+20251_333637819.3333333333334Topological domainCytoplasmic
HgeneANO1chr11:70017145chr14:23635749ENST00000530676+2025355_406637819.3333333333334Topological domainExtracellular
HgeneANO1chr11:70017145chr14:23635749ENST00000530676+2025428_519637819.3333333333334Topological domainCytoplasmic
HgeneANO1chr11:70017145chr14:23635749ENST00000530676+2025541_568637819.3333333333334Topological domainExtracellular
HgeneANO1chr11:70017145chr14:23635749ENST00000530676+2025590_607637819.3333333333334Topological domainCytoplasmic
HgeneANO1chr11:70017145chr14:23635749ENST00000355303+2226334_354783987.0TransmembraneHelical
HgeneANO1chr11:70017145chr14:23635749ENST00000355303+2226407_427783987.0TransmembraneHelical
HgeneANO1chr11:70017145chr14:23635749ENST00000355303+2226520_540783987.0TransmembraneHelical
HgeneANO1chr11:70017145chr14:23635749ENST00000355303+2226569_589783987.0TransmembraneHelical
HgeneANO1chr11:70017145chr14:23635749ENST00000355303+2226608_628783987.0TransmembraneHelical
HgeneANO1chr11:70017145chr14:23635749ENST00000355303+2226658_678783987.0TransmembraneHelical
HgeneANO1chr11:70017145chr14:23635749ENST00000355303+2226726_746783987.0TransmembraneHelical
HgeneANO1chr11:70017145chr14:23635749ENST00000355303+2226747_767783987.0TransmembraneHelical
HgeneANO1chr11:70017145chr14:23635749ENST00000398543+2024334_354637841.0TransmembraneHelical
HgeneANO1chr11:70017145chr14:23635749ENST00000398543+2024407_427637841.0TransmembraneHelical
HgeneANO1chr11:70017145chr14:23635749ENST00000398543+2024520_540637841.0TransmembraneHelical
HgeneANO1chr11:70017145chr14:23635749ENST00000398543+2024569_589637841.0TransmembraneHelical
HgeneANO1chr11:70017145chr14:23635749ENST00000398543+2024608_628637841.0TransmembraneHelical
HgeneANO1chr11:70017145chr14:23635749ENST00000530676+2025334_354637819.3333333333334TransmembraneHelical
HgeneANO1chr11:70017145chr14:23635749ENST00000530676+2025407_427637819.3333333333334TransmembraneHelical
HgeneANO1chr11:70017145chr14:23635749ENST00000530676+2025520_540637819.3333333333334TransmembraneHelical
HgeneANO1chr11:70017145chr14:23635749ENST00000530676+2025569_589637819.3333333333334TransmembraneHelical
HgeneANO1chr11:70017145chr14:23635749ENST00000530676+2025608_628637819.3333333333334TransmembraneHelical
TgeneSLC7A8chr11:70017145chr14:23635749ENST00000316902011113_13350536.0TransmembraneHelical
TgeneSLC7A8chr11:70017145chr14:23635749ENST00000316902011155_17550536.0TransmembraneHelical
TgeneSLC7A8chr11:70017145chr14:23635749ENST00000316902011189_20950536.0TransmembraneHelical
TgeneSLC7A8chr11:70017145chr14:23635749ENST00000316902011231_25150536.0TransmembraneHelical
TgeneSLC7A8chr11:70017145chr14:23635749ENST00000316902011268_28850536.0TransmembraneHelical
TgeneSLC7A8chr11:70017145chr14:23635749ENST00000316902011310_33050536.0TransmembraneHelical
TgeneSLC7A8chr11:70017145chr14:23635749ENST00000316902011362_38250536.0TransmembraneHelical
TgeneSLC7A8chr11:70017145chr14:23635749ENST00000316902011388_40850536.0TransmembraneHelical
TgeneSLC7A8chr11:70017145chr14:23635749ENST00000316902011424_44450536.0TransmembraneHelical
TgeneSLC7A8chr11:70017145chr14:23635749ENST00000316902011447_46750536.0TransmembraneHelical
TgeneSLC7A8chr11:70017145chr14:23635749ENST0000031690201172_9250536.0TransmembraneHelical
TgeneSLC7A8chr11:70017145chr14:23635749ENST0000042294108113_1330312.0TransmembraneHelical
TgeneSLC7A8chr11:70017145chr14:23635749ENST0000042294108155_1750312.0TransmembraneHelical
TgeneSLC7A8chr11:70017145chr14:23635749ENST0000042294108189_2090312.0TransmembraneHelical
TgeneSLC7A8chr11:70017145chr14:23635749ENST0000042294108231_2510312.0TransmembraneHelical
TgeneSLC7A8chr11:70017145chr14:23635749ENST0000042294108268_2880312.0TransmembraneHelical
TgeneSLC7A8chr11:70017145chr14:23635749ENST0000042294108310_3300312.0TransmembraneHelical
TgeneSLC7A8chr11:70017145chr14:23635749ENST0000042294108362_3820312.0TransmembraneHelical
TgeneSLC7A8chr11:70017145chr14:23635749ENST0000042294108388_4080312.0TransmembraneHelical
TgeneSLC7A8chr11:70017145chr14:23635749ENST000004229410840_600312.0TransmembraneHelical
TgeneSLC7A8chr11:70017145chr14:23635749ENST0000042294108424_4440312.0TransmembraneHelical
TgeneSLC7A8chr11:70017145chr14:23635749ENST0000042294108447_4670312.0TransmembraneHelical
TgeneSLC7A8chr11:70017145chr14:23635749ENST000004229410872_920312.0TransmembraneHelical
TgeneSLC7A8chr11:70017145chr14:23635749ENST0000045370209113_1330333.0TransmembraneHelical
TgeneSLC7A8chr11:70017145chr14:23635749ENST0000045370209155_1750333.0TransmembraneHelical
TgeneSLC7A8chr11:70017145chr14:23635749ENST0000045370209189_2090333.0TransmembraneHelical
TgeneSLC7A8chr11:70017145chr14:23635749ENST0000045370209231_2510333.0TransmembraneHelical
TgeneSLC7A8chr11:70017145chr14:23635749ENST0000045370209268_2880333.0TransmembraneHelical
TgeneSLC7A8chr11:70017145chr14:23635749ENST0000045370209310_3300333.0TransmembraneHelical
TgeneSLC7A8chr11:70017145chr14:23635749ENST0000045370209362_3820333.0TransmembraneHelical
TgeneSLC7A8chr11:70017145chr14:23635749ENST0000045370209388_4080333.0TransmembraneHelical
TgeneSLC7A8chr11:70017145chr14:23635749ENST000004537020940_600333.0TransmembraneHelical
TgeneSLC7A8chr11:70017145chr14:23635749ENST0000045370209424_4440333.0TransmembraneHelical
TgeneSLC7A8chr11:70017145chr14:23635749ENST0000045370209447_4670333.0TransmembraneHelical
TgeneSLC7A8chr11:70017145chr14:23635749ENST000004537020972_920333.0TransmembraneHelical
TgeneSLC7A8chr11:70017145chr14:23635749ENST0000052970509113_1330431.0TransmembraneHelical
TgeneSLC7A8chr11:70017145chr14:23635749ENST0000052970509155_1750431.0TransmembraneHelical
TgeneSLC7A8chr11:70017145chr14:23635749ENST0000052970509189_2090431.0TransmembraneHelical
TgeneSLC7A8chr11:70017145chr14:23635749ENST0000052970509231_2510431.0TransmembraneHelical
TgeneSLC7A8chr11:70017145chr14:23635749ENST0000052970509268_2880431.0TransmembraneHelical
TgeneSLC7A8chr11:70017145chr14:23635749ENST0000052970509310_3300431.0TransmembraneHelical
TgeneSLC7A8chr11:70017145chr14:23635749ENST0000052970509362_3820431.0TransmembraneHelical
TgeneSLC7A8chr11:70017145chr14:23635749ENST0000052970509388_4080431.0TransmembraneHelical
TgeneSLC7A8chr11:70017145chr14:23635749ENST000005297050940_600431.0TransmembraneHelical
TgeneSLC7A8chr11:70017145chr14:23635749ENST0000052970509424_4440431.0TransmembraneHelical
TgeneSLC7A8chr11:70017145chr14:23635749ENST0000052970509447_4670431.0TransmembraneHelical
TgeneSLC7A8chr11:70017145chr14:23635749ENST000005297050972_920431.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneANO1chr11:70017145chr14:23635749ENST00000316296+1171_3330643.0Topological domainCytoplasmic
HgeneANO1chr11:70017145chr14:23635749ENST00000316296+117355_4060643.0Topological domainExtracellular
HgeneANO1chr11:70017145chr14:23635749ENST00000316296+117428_5190643.0Topological domainCytoplasmic
HgeneANO1chr11:70017145chr14:23635749ENST00000316296+117541_5680643.0Topological domainExtracellular
HgeneANO1chr11:70017145chr14:23635749ENST00000316296+117590_6070643.0Topological domainCytoplasmic
HgeneANO1chr11:70017145chr14:23635749ENST00000316296+117629_6570643.0Topological domainExtracellular
HgeneANO1chr11:70017145chr14:23635749ENST00000316296+117679_7250643.0Topological domainCytoplasmic
HgeneANO1chr11:70017145chr14:23635749ENST00000316296+117768_7840643.0Topological domainCytoplasmic
HgeneANO1chr11:70017145chr14:23635749ENST00000316296+117806_8920643.0Topological domainExtracellular
HgeneANO1chr11:70017145chr14:23635749ENST00000316296+117914_9860643.0Topological domainCytoplasmic
HgeneANO1chr11:70017145chr14:23635749ENST00000355303+2226806_892783987.0Topological domainExtracellular
HgeneANO1chr11:70017145chr14:23635749ENST00000355303+2226914_986783987.0Topological domainCytoplasmic
HgeneANO1chr11:70017145chr14:23635749ENST00000398543+2024629_657637841.0Topological domainExtracellular
HgeneANO1chr11:70017145chr14:23635749ENST00000398543+2024679_725637841.0Topological domainCytoplasmic
HgeneANO1chr11:70017145chr14:23635749ENST00000398543+2024768_784637841.0Topological domainCytoplasmic
HgeneANO1chr11:70017145chr14:23635749ENST00000398543+2024806_892637841.0Topological domainExtracellular
HgeneANO1chr11:70017145chr14:23635749ENST00000398543+2024914_986637841.0Topological domainCytoplasmic
HgeneANO1chr11:70017145chr14:23635749ENST00000530676+2025629_657637819.3333333333334Topological domainExtracellular
HgeneANO1chr11:70017145chr14:23635749ENST00000530676+2025679_725637819.3333333333334Topological domainCytoplasmic
HgeneANO1chr11:70017145chr14:23635749ENST00000530676+2025768_784637819.3333333333334Topological domainCytoplasmic
HgeneANO1chr11:70017145chr14:23635749ENST00000530676+2025806_892637819.3333333333334Topological domainExtracellular
HgeneANO1chr11:70017145chr14:23635749ENST00000530676+2025914_986637819.3333333333334Topological domainCytoplasmic
HgeneANO1chr11:70017145chr14:23635749ENST00000316296+117334_3540643.0TransmembraneHelical
HgeneANO1chr11:70017145chr14:23635749ENST00000316296+117407_4270643.0TransmembraneHelical
HgeneANO1chr11:70017145chr14:23635749ENST00000316296+117520_5400643.0TransmembraneHelical
HgeneANO1chr11:70017145chr14:23635749ENST00000316296+117569_5890643.0TransmembraneHelical
HgeneANO1chr11:70017145chr14:23635749ENST00000316296+117608_6280643.0TransmembraneHelical
HgeneANO1chr11:70017145chr14:23635749ENST00000316296+117658_6780643.0TransmembraneHelical
HgeneANO1chr11:70017145chr14:23635749ENST00000316296+117726_7460643.0TransmembraneHelical
HgeneANO1chr11:70017145chr14:23635749ENST00000316296+117747_7670643.0TransmembraneHelical
HgeneANO1chr11:70017145chr14:23635749ENST00000316296+117785_8050643.0TransmembraneHelical
HgeneANO1chr11:70017145chr14:23635749ENST00000316296+117893_9130643.0TransmembraneHelical
HgeneANO1chr11:70017145chr14:23635749ENST00000355303+2226785_805783987.0TransmembraneHelical
HgeneANO1chr11:70017145chr14:23635749ENST00000355303+2226893_913783987.0TransmembraneHelical
HgeneANO1chr11:70017145chr14:23635749ENST00000398543+2024658_678637841.0TransmembraneHelical
HgeneANO1chr11:70017145chr14:23635749ENST00000398543+2024726_746637841.0TransmembraneHelical
HgeneANO1chr11:70017145chr14:23635749ENST00000398543+2024747_767637841.0TransmembraneHelical
HgeneANO1chr11:70017145chr14:23635749ENST00000398543+2024785_805637841.0TransmembraneHelical
HgeneANO1chr11:70017145chr14:23635749ENST00000398543+2024893_913637841.0TransmembraneHelical
HgeneANO1chr11:70017145chr14:23635749ENST00000530676+2025658_678637819.3333333333334TransmembraneHelical
HgeneANO1chr11:70017145chr14:23635749ENST00000530676+2025726_746637819.3333333333334TransmembraneHelical
HgeneANO1chr11:70017145chr14:23635749ENST00000530676+2025747_767637819.3333333333334TransmembraneHelical
HgeneANO1chr11:70017145chr14:23635749ENST00000530676+2025785_805637819.3333333333334TransmembraneHelical
HgeneANO1chr11:70017145chr14:23635749ENST00000530676+2025893_913637819.3333333333334TransmembraneHelical
TgeneSLC7A8chr11:70017145chr14:23635749ENST0000031690201140_6050536.0TransmembraneHelical


Top

Fusion Gene Sequence for ANO1-SLC7A8


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>4864_4864_1_ANO1-SLC7A8_ANO1_chr11_70017145_ENST00000355303_SLC7A8_chr14_23635749_ENST00000316902_length(transcript)=5994nt_BP=2655nt
AAAGGCGGGCCGGCTGGCGTCCAAGTTCCTGACCAGGCGCGGGCCGGCCCGCGGGACCAGCAGCCGGGTGGCGGCGCGATCGGCCCCGAG
AGGCTCAGGCGCCCCCCGCATCGAGCGCGCGGGCCGGGCGGGCCAGGGCGGCGGGCGGAGCGGGAGGCGGCCACGTCCCCGGCGGGCCTG
GGCGCGGGGAGGCCCGGCCCCCTGCGAGCGCGCCGCGAACGCTGCGGTCTCCGCCCGCAGAGGCCGCCGGGGCCGTGGATGGGGAGGGCG
CGCCGCCCGGCGGTCCCAGCGCACAGGCGGCCACGATGAGGGTCAACGAGAAGTACTCGACGCTCCCGGCCGAGGACCGCAGCGTCCACA
TCATCAACATCTGCGCCATCGAGGACATCGGCTACCTGCCGTCCGAGGGCACGCTGCTGAACTCCTTATCTGTGGACCCTGATGCCGAGT
GCAAGTATGGCCTGTACTTCAGGGACGGCCGGCGCAAGGTGGACTACATCCTGGTGTACCATCACAAGAGGCCCTCGGGCAACCGGACCC
TGGTCAGGAGGGTGCAGCACAGCGACACCCCCTCTGGGGCTCGCAGCGTCAAGCAGGACCACCCCCTGCCGGGCAAGGGGGCGTCGCTGG
ATGCAGGCTCGGGGGAGCCCCCGATGGACTACCACGAGGATGACAAGCGCTTCCGCAGGGAGGAGTACGAGGGCAACCTCCTGGAGGCGG
GCCTGGAGCTGGAGCGGGACGAGGACACTAAAATCCACGGAGTCGGGTTTGTGAAAATCCATGCCCCCTGGAACGTGCTGTGCAGAGAGG
CCGAGTTTCTGAAACTGAAGATGCCGACGAAGAAGATGTACCACATTAATGAGACCCGTGGCCTCCTGAAAAAAATCAACTCTGTGCTCC
AGAAAATCACAGATCCCATCCAGCCCAAAGTGGCTGAGCACAGGCCCCAGACCATGAAGAGACTCTCCTATCCCTTCTCCCGGGAGAAGC
AGCATCTATTTGACTTGTCTGATAAGGATTCCTTTTTCGACAGCAAAACCCGGAGCACGATTGTCTATGAGATCTTGAAGAGAACGACGT
GTACAAAGGCCAAGTACAGCATGGGCATCACGAGCCTGCTGGCCAATGGTGTGTACGCGGCTGCATACCCACTGCACGATGGAGACTACA
ACGGTGAAAACGTCGAGTTCAACGACAGAAAACTCCTGTACGAAGAGTGGGCACGCTATGGAGTTTTCTATAAGTACCAGCCCATCGACC
TGGTCAGGAAGTATTTTGGGGAGAAGATCGGCCTGTACTTCGCCTGGCTGGGCGTGTACACCCAGATGCTCATCCCTGCCTCCATCGTGG
GAATCATTGTCTTCCTGTACGGATGCGCCACCATGGATGAAAACATCCCCAGCATGGAGATGTGTGACCAGAGACACAATATCACCATGT
GCCCGCTTTGCGACAAGACCTGCAGCTACTGGAAGATGAGCTCAGCCTGCGCCACGGCCCGCGCCAGCCACCTCTTCGACAACCCCGCCA
CGGTCTTCTTCTCTGTCTTCATGGCCCTCTGGGCTGCCACCTTCATGGAGCACTGGAAGCGGAAACAGATGCGACTCAACTACCGCTGGG
ACCTCACGGGCTTTGAAGAGGAAGAGGAGGCTGTCAAGGATCATCCTAGAGCTGAATACGAAGCCAGAGTCTTGGAGAAGTCTCTGAAGA
AAGAGTCCAGAAACAAAGAGAAGCGCCGGCATATTCCAGAGGAGTCAACAAACAAATGGAAGCAGAGGGTTAAGACAGCCATGGCGGGGG
TGAAATTGACTGACAAAGTGAAGCTGACATGGAGAGATCGGTTCCCAGCCTACCTCACTAACTTGGTCTCCATCATCTTCATGATTGCAG
TGACGTTTGCCATCGTCCTCGGCGTCATCATCTACAGAATCTCCATGGCCGCCGCCTTGGCCATGAACTCCTCCCCCTCCGTGCGGTCCA
ACATCCGGGTCACAGTCACAGCCACCGCAGTCATCATCAACCTAGTGGTCATCATCCTCCTGGACGAGGTGTATGGCTGCATAGCCCGAT
GGCTCACCAAGATCGAGGTCCCAAAGACGGAGAAAAGCTTTGAGGAGAGGCTGATCTTCAAGGCTTTCCTGCTGAAGTTTGTGAATTCCT
ACACCCCCATCTTTTACGTGGCGTTCTTCAAAGGCCGGTTTGTTGGACGCCCGGGCGACTACGTGTACATTTTCCGTTCCTTCCGAATGG
AAGAGTGTGCGCCAGGGGGCTGCCTGATGGAGCTATGCATCCAGCTCAGCATCATCATGCTGGGGAAACAGCTGATCCAGAACAACCTGT
TCGAGATCGGCATCCCGAAGATGAAGAAGCTCATCCGCTACCTGAAGCTGAAGCAGCAGAGCCCCCCTGACCACGAGGAGTGTGTGAAGA
GGAAACAGCGGTACGAGGTGGATTACAACCTGGAGCCCTTCGCGGGCCTCACCCCAGAGTACATGGAAATGATCATCCAGTTTGGCTTCG
TCACCCTGTTTGTCGCCTCCTTCCCCCTGGCCCCACTGTTTGCGCTGCTGAACAACATCATCGAGATCCGCCTGGACGCCAAAAAGTTTG
TCACTGAGCTCCGAAGGCCGGTAGCTGTCAGAGCCAAAGACATCGGGAACATCATCGGCTCTGGAATCTTTGTCTCGCCAAAGGGAGTGC
TGGAGAATGCTGGTTCTGTGGGCCTTGCTCTCATCGTCTGGATTGTGACGGGCTTCATCACAGTTGTGGGAGCCCTCTGCTATGCTGAAC
TCGGGGTCACCATCCCCAAATCTGGAGGTGACTACTCCTATGTCAAGGACATCTTCGGAGGACTGGCTGGGTTCCTGAGGCTGTGGATTG
CTGTGCTGGTGATCTACCCCACCAACCAGGCTGTCATCGCCCTCACCTTCTCCAACTACGTGCTGCAGCCGCTCTTCCCCACCTGCTTCC
CCCCAGAGTCTGGCCTTCGGCTCCTGGCTGCCATCTGCTTATTGCTCCTCACATGGGTCAACTGTTCCAGTGTGCGGTGGGCCACCCGGG
TTCAAGACATCTTCACAGCTGGGAAGCTCCTGGCCTTGGCCCTGATTATCATCATGGGGATTGTACAGATATGCAAAGGAGAGTACTTCT
GGCTGGAGCCAAAGAATGCATTTGAGAATTTCCAGGAACCTGACATCGGCCTCGTCGCACTGGCTTTCCTTCAGGGCTCCTTTGCCTATG
GAGGCTGGAACTTTCTGAATTACGTGACTGAGGAGCTTGTTGATCCCTACAAGAACCTTCCCAGAGCCATCTTCATCTCCATCCCACTGG
TCACATTTGTGTATGTCTTTGCCAATGTCGCTTATGTCACTGCAATGTCCCCCCAGGAGCTGCTGGCATCCAACGCCGTCGCTGTGACTT
TTGGAGAGAAGCTCCTAGGAGTCATGGCCTGGATCATGCCCATTTCTGTTGCCCTGTCCACATTTGGAGGAGTTAATGGGTCTCTCTTCA
CCTCCTCTCGGCTGTTCTTCGCTGGAGCCCGAGAGGGCCACCTTCCCAGTGTGTTGGCCATGATCCACGTGAAGCGCTGCACCCCAATCC
CAGCCCTGCTCTTCACATGCATCTCCACCCTGCTGATGCTGGTCACCAGCGACATGTACACACTCATCAACTATGTGGGCTTCATCAACT
ACCTCTTCTATGGGGTCACGGTTGCTGGACAGATAGTCCTTCGCTGGAAGAAGCCTGATATCCCCCGCCCCATCAAGATCAACCTGCTGT
TCCCCATCATCTACTTGCTGTTCTGGGCCTTCCTGCTGGTCTTCAGCCTGTGGTCAGAGCCGGTGGTGTGTGGCATTGGCCTGGCCATCA
TGCTGACAGGAGTGCCTGTCTATTTCCTGGGTGTTTACTGGCAACACAAGCCCAAGTGTTTCAGTGACTTCATTGAGCTGCTAACCCTGG
TGAGCCAGAAGATGTGTGTGGTCGTGTACCCCGAGGTGGAGCGGGGCTCAGGGACAGAGGAGGCTAATGAGGACATGGAGGAGCAGCAGC
AGCCCATGTACCAACCCACTCCCACGAAGGACAAGGACGTGGCGGGGCAGCCCCAGCCCTGAGGACCACCATTCCCTGGCTACTCTCTCC
TTCCTCCCCCTTTTATCCTACCTCCCTGCCTTGGTCCTGCCAACACATGCGAGTACACACACACCCCTCTCTCTGCTTTTGTCAGGCAGT
GGTAGGACTTTGGTGTGGGTGGTGAGAAATTGTAAACAAAAACTGACATTCATACCCAAAGAACCAGCCTCTCACCCCAGGGTCCATGTC
CCAGGCCCCACTCCAGTGCTGCCCACACTCCCAGCTGCTGGAGGAGAGGGGAGATGCCAAGGTGCCCTGCAGGACCTCCCTCCGGGCCAC
ACCCTCAGCTGCCTCTTCAGGAACCGGAGCTCATTACTGCCTTCCCTCCCAGGGAGGCCCCTTCAGAGAGGAGAGGCCACAGGAGCTGCA
TTGTGGGGGGACAGGCTCAAGCAATTCTGTCCCCATCAAGGGGTCAGCTGGAGAGACCCAAGACCCTATCTGTTCACCAGGGACCCAAAA
TCCAAGGGGATGCTTCCCTCTGCCCTCTTTCCTGCCCCTCCCCATCATACCTGCACCCACCCCAGCCAGGGCTCCCTGTCCAGAATTCGG
TTCTCCTCAGGACGCCAACTCCCAGAGCTAAGGACCAAGGAGAAGAACAGCCTCTCCACCCCCAAGCCAGGCGGTTGAGGAACATATTGA
GAAAGGTTCAGATTGCAGAAACCCAGCCCTGCCCCTGCCTCCTGCATCCAGCCCCCAACATGGTGCCAAAGCTTCCAGAAGCCAAAAAGC
TTCTGATTTTTAAGGTAGTGGGCATCTCTCTCCTAATGACGAAGCTGCTCAGCAACTCCACCTGCCCGCCGCAGGAAGGAGCAGTCCCCT
GCTATCCCTGCAGCCACTCCCAGCACACCCGCACACAGCCAGCACCACCGCCCCCACCGTGCACTTCTCCTCTCTGGGCCTTGGCTTGGG
ACCAGGTACGAAGGATCCCCAAGCCCTTCAGGCCTGAGATCAGAGCCAGATCAGCCTTAAGTCACCTCCCATCCAAGAACTTGGCCTAAA
AATACTCCCCTATTTCTAACCCTCAGGACGGATCTGATATTAAATGCCTTCCCTGGGAGGAAGGGTGCTTTCCCCCTCCCTAGAGGTGCC
CATTCCATACCCTGGGAGACTGAGGAGAGCATTGGCTGAAGCCCAGTTCCTTTCCCATCCATCCCCAACTCCAATAATCCCCCACTCCTC
GCAGGTCTCAGTGTCATGCTGTCTTGGGGCAGGGTGAAAGGGTAGTGGCAGCAGGGCGCCCACTCTGGAGATCCTCAAAAAAGGCCCTCC
TCTGTGGCTGGCAGCCTCTGACCTTTCCCTGGGCTTCAAAGGAAGGCTATGGAGTTTGCTGTGGGCCCTGCAACCTTCCCAGCCACTCCT
GCTGCACTAAGGACTTAGGATCCTTTTATCACAAATCGGGATTCTCTCCCCCACCCCGAATTCTGTCTGCTTAAACTGGAATACACAGGA
GCCCTTCCTGGCCTGGATGGTGTCTCCCAGCTTCCCCGCCCAGCTTGCCCACCCCATAGTTGGTGAGATGCCAAGTTTGGTCTGAGTTGT
GACCCCTTCAGAGTAGATGCCCGGCAGGCTGGGGTTGGCCCCTGGAGGGTCAGGGGACCATCTTCTTATTCCCTCTTTTCTCATTCCTCC
AACTTCCTCCCCTCCTTCAATTATTTTTTTGTAAAGTTGATGCCTTACTTTTTGGATAAATATTTTTGAAGCTGGTATTTCTATTTCTTT
TGGATTTTTTTTAATGTAAGGTTGTTTTGGGGGATGGAGTTAGAACCTTAATGATAATTTCTTTCGTTTGGTGTAGGTTTTAGAGATTTG

>4864_4864_1_ANO1-SLC7A8_ANO1_chr11_70017145_ENST00000355303_SLC7A8_chr14_23635749_ENST00000316902_length(amino acids)=1296AA_BP=811
MRSPPAEAAGAVDGEGAPPGGPSAQAATMRVNEKYSTLPAEDRSVHIINICAIEDIGYLPSEGTLLNSLSVDPDAECKYGLYFRDGRRKV
DYILVYHHKRPSGNRTLVRRVQHSDTPSGARSVKQDHPLPGKGASLDAGSGEPPMDYHEDDKRFRREEYEGNLLEAGLELERDEDTKIHG
VGFVKIHAPWNVLCREAEFLKLKMPTKKMYHINETRGLLKKINSVLQKITDPIQPKVAEHRPQTMKRLSYPFSREKQHLFDLSDKDSFFD
SKTRSTIVYEILKRTTCTKAKYSMGITSLLANGVYAAAYPLHDGDYNGENVEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEKIGLYF
AWLGVYTQMLIPASIVGIIVFLYGCATMDENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMALWAAT
FMEHWKRKQMRLNYRWDLTGFEEEEEAVKDHPRAEYEARVLEKSLKKESRNKEKRRHIPEESTNKWKQRVKTAMAGVKLTDKVKLTWRDR
FPAYLTNLVSIIFMIAVTFAIVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEKSF
EERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRY
LKLKQQSPPDHEECVKRKQRYEVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAVRAKD
IGNIIGSGIFVSPKGVLENAGSVGLALIVWIVTGFITVVGALCYAELGVTIPKSGGDYSYVKDIFGGLAGFLRLWIAVLVIYPTNQAVIA
LTFSNYVLQPLFPTCFPPESGLRLLAAICLLLLTWVNCSSVRWATRVQDIFTAGKLLALALIIIMGIVQICKGEYFWLEPKNAFENFQEP
DIGLVALAFLQGSFAYGGWNFLNYVTEELVDPYKNLPRAIFISIPLVTFVYVFANVAYVTAMSPQELLASNAVAVTFGEKLLGVMAWIMP
ISVALSTFGGVNGSLFTSSRLFFAGAREGHLPSVLAMIHVKRCTPIPALLFTCISTLLMLVTSDMYTLINYVGFINYLFYGVTVAGQIVL
RWKKPDIPRPIKINLLFPIIYLLFWAFLLVFSLWSEPVVCGIGLAIMLTGVPVYFLGVYWQHKPKCFSDFIELLTLVSQKMCVVVYPEVE

--------------------------------------------------------------
>4864_4864_2_ANO1-SLC7A8_ANO1_chr11_70017145_ENST00000355303_SLC7A8_chr14_23635749_ENST00000469263_length(transcript)=5334nt_BP=2655nt
AAAGGCGGGCCGGCTGGCGTCCAAGTTCCTGACCAGGCGCGGGCCGGCCCGCGGGACCAGCAGCCGGGTGGCGGCGCGATCGGCCCCGAG
AGGCTCAGGCGCCCCCCGCATCGAGCGCGCGGGCCGGGCGGGCCAGGGCGGCGGGCGGAGCGGGAGGCGGCCACGTCCCCGGCGGGCCTG
GGCGCGGGGAGGCCCGGCCCCCTGCGAGCGCGCCGCGAACGCTGCGGTCTCCGCCCGCAGAGGCCGCCGGGGCCGTGGATGGGGAGGGCG
CGCCGCCCGGCGGTCCCAGCGCACAGGCGGCCACGATGAGGGTCAACGAGAAGTACTCGACGCTCCCGGCCGAGGACCGCAGCGTCCACA
TCATCAACATCTGCGCCATCGAGGACATCGGCTACCTGCCGTCCGAGGGCACGCTGCTGAACTCCTTATCTGTGGACCCTGATGCCGAGT
GCAAGTATGGCCTGTACTTCAGGGACGGCCGGCGCAAGGTGGACTACATCCTGGTGTACCATCACAAGAGGCCCTCGGGCAACCGGACCC
TGGTCAGGAGGGTGCAGCACAGCGACACCCCCTCTGGGGCTCGCAGCGTCAAGCAGGACCACCCCCTGCCGGGCAAGGGGGCGTCGCTGG
ATGCAGGCTCGGGGGAGCCCCCGATGGACTACCACGAGGATGACAAGCGCTTCCGCAGGGAGGAGTACGAGGGCAACCTCCTGGAGGCGG
GCCTGGAGCTGGAGCGGGACGAGGACACTAAAATCCACGGAGTCGGGTTTGTGAAAATCCATGCCCCCTGGAACGTGCTGTGCAGAGAGG
CCGAGTTTCTGAAACTGAAGATGCCGACGAAGAAGATGTACCACATTAATGAGACCCGTGGCCTCCTGAAAAAAATCAACTCTGTGCTCC
AGAAAATCACAGATCCCATCCAGCCCAAAGTGGCTGAGCACAGGCCCCAGACCATGAAGAGACTCTCCTATCCCTTCTCCCGGGAGAAGC
AGCATCTATTTGACTTGTCTGATAAGGATTCCTTTTTCGACAGCAAAACCCGGAGCACGATTGTCTATGAGATCTTGAAGAGAACGACGT
GTACAAAGGCCAAGTACAGCATGGGCATCACGAGCCTGCTGGCCAATGGTGTGTACGCGGCTGCATACCCACTGCACGATGGAGACTACA
ACGGTGAAAACGTCGAGTTCAACGACAGAAAACTCCTGTACGAAGAGTGGGCACGCTATGGAGTTTTCTATAAGTACCAGCCCATCGACC
TGGTCAGGAAGTATTTTGGGGAGAAGATCGGCCTGTACTTCGCCTGGCTGGGCGTGTACACCCAGATGCTCATCCCTGCCTCCATCGTGG
GAATCATTGTCTTCCTGTACGGATGCGCCACCATGGATGAAAACATCCCCAGCATGGAGATGTGTGACCAGAGACACAATATCACCATGT
GCCCGCTTTGCGACAAGACCTGCAGCTACTGGAAGATGAGCTCAGCCTGCGCCACGGCCCGCGCCAGCCACCTCTTCGACAACCCCGCCA
CGGTCTTCTTCTCTGTCTTCATGGCCCTCTGGGCTGCCACCTTCATGGAGCACTGGAAGCGGAAACAGATGCGACTCAACTACCGCTGGG
ACCTCACGGGCTTTGAAGAGGAAGAGGAGGCTGTCAAGGATCATCCTAGAGCTGAATACGAAGCCAGAGTCTTGGAGAAGTCTCTGAAGA
AAGAGTCCAGAAACAAAGAGAAGCGCCGGCATATTCCAGAGGAGTCAACAAACAAATGGAAGCAGAGGGTTAAGACAGCCATGGCGGGGG
TGAAATTGACTGACAAAGTGAAGCTGACATGGAGAGATCGGTTCCCAGCCTACCTCACTAACTTGGTCTCCATCATCTTCATGATTGCAG
TGACGTTTGCCATCGTCCTCGGCGTCATCATCTACAGAATCTCCATGGCCGCCGCCTTGGCCATGAACTCCTCCCCCTCCGTGCGGTCCA
ACATCCGGGTCACAGTCACAGCCACCGCAGTCATCATCAACCTAGTGGTCATCATCCTCCTGGACGAGGTGTATGGCTGCATAGCCCGAT
GGCTCACCAAGATCGAGGTCCCAAAGACGGAGAAAAGCTTTGAGGAGAGGCTGATCTTCAAGGCTTTCCTGCTGAAGTTTGTGAATTCCT
ACACCCCCATCTTTTACGTGGCGTTCTTCAAAGGCCGGTTTGTTGGACGCCCGGGCGACTACGTGTACATTTTCCGTTCCTTCCGAATGG
AAGAGTGTGCGCCAGGGGGCTGCCTGATGGAGCTATGCATCCAGCTCAGCATCATCATGCTGGGGAAACAGCTGATCCAGAACAACCTGT
TCGAGATCGGCATCCCGAAGATGAAGAAGCTCATCCGCTACCTGAAGCTGAAGCAGCAGAGCCCCCCTGACCACGAGGAGTGTGTGAAGA
GGAAACAGCGGTACGAGGTGGATTACAACCTGGAGCCCTTCGCGGGCCTCACCCCAGAGTACATGGAAATGATCATCCAGTTTGGCTTCG
TCACCCTGTTTGTCGCCTCCTTCCCCCTGGCCCCACTGTTTGCGCTGCTGAACAACATCATCGAGATCCGCCTGGACGCCAAAAAGTTTG
TCACTGAGCTCCGAAGGCCGGTAGCTGTCAGAGCCAAAGACATCGGGAACATCATCGGCTCTGGAATCTTTGTCTCGCCAAAGGGAGTGC
TGGAGAATGCTGGTTCTGTGGGCCTTGCTCTCATCGTCTGGATTGTGACGGGCTTCATCACAGTTGTGGGAGCCCTCTGCTATGCTGAAC
TCGGGGTCACCATCCCCAAATCTGGAGGTGACTACTCCTATGTCAAGGACATCTTCGGAGGACTGGCTGGGTTCCTGAGGCTGTGGATTG
CTGTGCTGGTGATCTACCCCACCAACCAGGCTGTCATCGCCCTCACCTTCTCCAACTACGTGCTGCAGCCGCTCTTCCCCACCTGCTTCC
CCCCAGAGTCTGGCCTTCGGCTCCTGGCTGCCATCTGCTTATTGCTCCTCACATGGGTCAACTGTTCCAGTGTGCGGTGGGCCACCCGGG
TTCAAGACATCTTCACAGCTGGGAAGCTCCTGGCCTTGGCCCTGATTATCATCATGGGGATTGTACAGATATGCAAAGGAGAGTACTTCT
GGCTGGAGCCAAAGAATGCATTTGAGAATTTCCAGGAACCTGACATCGGCCTCGTCGCACTGGCTTTCCTTCAGGGCTCCTTTGCCTATG
GAGGCTGGAACTTTCTGAATTACGTGACTGAGGAGCTTGTTGATCCCTACAAAGCTGCTAACCCTGGTGAGCCAGAAGATGTGTGTGGTC
GTGTACCCCGAGGTGGAGCGGGGCTCAGGGACAGAGGAGGCTAATGAGGACATGGAGGAGCAGCAGCAGCCCATGTACCAACCCACTCCC
ACGAAGGACAAGGACGTGGCGGGGCAGCCCCAGCCCTGAGGACCACCATTCCCTGGCTACTCTCTCCTTCCTCCCCCTTTTATCCTACCT
CCCTGCCTTGGTCCTGCCAACACATGCGAGTACACACACACCCCTCTCTCTGCTTTTGTCAGGCAGTGGTAGGACTTTGGTGTGGGTGGT
GAGAAATTGTAAACAAAAACTGACATTCATACCCAAAGAACCAGCCTCTCACCCCAGGGTCCATGTCCCAGGCCCCACTCCAGTGCTGCC
CACACTCCCAGCTGCTGGAGGAGAGGGGAGATGCCAAGGTGCCCTGCAGGACCTCCCTCCGGGCCACACCCTCAGCTGCCTCTTCAGGAA
CCGGAGCTCATTACTGCCTTCCCTCCCAGGGAGGCCCCTTCAGAGAGGAGAGGCCACAGGAGCTGCATTGTGGGGGGACAGGCTCAAGCA
ATTCTGTCCCCATCAAGGGGTCAGCTGGAGAGACCCAAGACCCTATCTGTTCACCAGGGACCCAAAATCCAAGGGGATGCTTCCCTCTGC
CCTCTTTCCTGCCCCTCCCCATCATACCTGCACCCACCCCAGCCAGGGCTCCCTGTCCAGAATTCGGTTCTCCTCAGGACGCCAACTCCC
AGAGCTAAGGACCAAGGAGAAGAACAGCCTCTCCACCCCCAAGCCAGGCGGTTGAGGAACATATTGAGAAAGGTTCAGATTGCAGAAACC
CAGCCCTGCCCCTGCCTCCTGCATCCAGCCCCCAACATGGTGCCAAAGCTTCCAGAAGCCAAAAAGCTTCTGATTTTTAAGGTAGTGGGC
ATCTCTCTCCTAATGACGAAGCTGCTCAGCAACTCCACCTGCCCGCCGCAGGAAGGAGCAGTCCCCTGCTATCCCTGCAGCCACTCCCAG
CACACCCGCACACAGCCAGCACCACCGCCCCCACCGTGCACTTCTCCTCTCTGGGCCTTGGCTTGGGACCAGGTACGAAGGATCCCCAAG
CCCTTCAGGCCTGAGATCAGAGCCAGATCAGCCTTAAGTCACCTCCCATCCAAGAACTTGGCCTAAAAATACTCCCCTATTTCTAACCCT
CAGGACGGATCTGATATTAAATGCCTTCCCTGGGAGGAAGGGTGCTTTCCCCCTCCCTAGAGGTGCCCATTCCATACCCTGGGAGACTGA
GGAGAGCATTGGCTGAAGCCCAGTTCCTTTCCCATCCATCCCCAACTCCAATAATCCCCCACTCCTCGCAGGTCTCAGTGTCATGCTGTC
TTGGGGCAGGGTGAAAGGGTAGTGGCAGCAGGGCGCCCACTCTGGAGATCCTCAAAAAAGGCCCTCCTCTGTGGCTGGCAGCCTCTGACC
TTTCCCTGGGCTTCAAAGGAAGGCTATGGAGTTTGCTGTGGGCCCTGCAACCTTCCCAGCCACTCCTGCTGCACTAAGGACTTAGGATCC
TTTTATCACAAATCGGGATTCTCTCCCCCACCCCGAATTCTGTCTGCTTAAACTGGAATACACAGGAGCCCTTCCTGGCCTGGATGGTGT
CTCCCAGCTTCCCCGCCCAGCTTGCCCACCCCATAGTTGGTGAGATGCCAAGTTTGGTCTGAGTTGTGACCCCTTCAGAGTAGATGCCCG
GCAGGCTGGGGTTGGCCCCTGGAGGGTCAGGGGACCATCTTCTTATTCCCTCTTTTCTCATTCCTCCAACTTCCTCCCCTCCTTCAATTA
TTTTTTTGTAAAGTTGATGCCTTACTTTTTGGATAAATATTTTTGAAGCTGGTATTTCTATTTCTTTTGGATTTTTTTTAATGTAAGGTT
GTTTTGGGGGATGGAGTTAGAACCTTAATGATAATTTCTTTCGTTTGGTGTAGGTTTTAGAGATTTGTTTTGTGGAGAGGTTTTTTTCTT

>4864_4864_2_ANO1-SLC7A8_ANO1_chr11_70017145_ENST00000355303_SLC7A8_chr14_23635749_ENST00000469263_length(amino acids)=1050AA_BP=811
MRSPPAEAAGAVDGEGAPPGGPSAQAATMRVNEKYSTLPAEDRSVHIINICAIEDIGYLPSEGTLLNSLSVDPDAECKYGLYFRDGRRKV
DYILVYHHKRPSGNRTLVRRVQHSDTPSGARSVKQDHPLPGKGASLDAGSGEPPMDYHEDDKRFRREEYEGNLLEAGLELERDEDTKIHG
VGFVKIHAPWNVLCREAEFLKLKMPTKKMYHINETRGLLKKINSVLQKITDPIQPKVAEHRPQTMKRLSYPFSREKQHLFDLSDKDSFFD
SKTRSTIVYEILKRTTCTKAKYSMGITSLLANGVYAAAYPLHDGDYNGENVEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEKIGLYF
AWLGVYTQMLIPASIVGIIVFLYGCATMDENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMALWAAT
FMEHWKRKQMRLNYRWDLTGFEEEEEAVKDHPRAEYEARVLEKSLKKESRNKEKRRHIPEESTNKWKQRVKTAMAGVKLTDKVKLTWRDR
FPAYLTNLVSIIFMIAVTFAIVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEKSF
EERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRY
LKLKQQSPPDHEECVKRKQRYEVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAVRAKD
IGNIIGSGIFVSPKGVLENAGSVGLALIVWIVTGFITVVGALCYAELGVTIPKSGGDYSYVKDIFGGLAGFLRLWIAVLVIYPTNQAVIA
LTFSNYVLQPLFPTCFPPESGLRLLAAICLLLLTWVNCSSVRWATRVQDIFTAGKLLALALIIIMGIVQICKGEYFWLEPKNAFENFQEP

--------------------------------------------------------------
>4864_4864_3_ANO1-SLC7A8_ANO1_chr11_70017145_ENST00000398543_SLC7A8_chr14_23635749_ENST00000316902_length(transcript)=5648nt_BP=2309nt
GGATGGGGAGGGCGCGCCGCCCGGCGGTCCCAGCGCACAGGCGGCCACGATGAGGGTCAACGAGAAGTACTCGACGCTCCCGGCCGAGGA
CCGCAGCGTCCACATCATCAACATCTGCGCCATCGAGGACATCGGCTACCTGCCGTCCGAGGGCACGCTGCTGAACTCCTTATCTGTGGA
CCCTGATGCCGAGTGCAAGTATGGCCTGTACTTCAGGGACGGCCGGCGCAAGGTGGACTACATCCTGGTGTACCATCACAAGAGGCCCTC
GGGCAACCGGACCCTGGTCAGGAGGGTGCAGCACAGCGACACCCCCTCTGGGGCTCGCAGCGTCAAGCAGGACCACCCCCTGCCGGGCAA
GGGGGCGTCGCTGGATGCAGGCTCGGGGGAGCCCCCGATGGACTACCACGAGGATGACAAGCGCTTCCGCAGGGAGGAGTACGAGGGCAA
CCTCCTGGAGGCGGGCCTGGAGCTGGAGCGGGACGAGGACACTAAAATCCACGGAGTCGGGTTTGTGAAAATCCATGCCCCCTGGAACGT
GCTGTGCAGAGAGGCCGAGTTTCTGAAACTGAAGATGCCGACGAAGAAGATGTACCACATTAATGAGACCCGTGGCCTCCTGAAAAAAAT
CAACTCTGTGCTCCAGAAAATCACAGATCCCATCCAGCCCAAAGTGGCTGAGCACAGGCCCCAGACCATGAAGAGACTCTCCTATCCCTT
CTCCCGGGAGAAGCAGCATCTATTTGACTTGTCTGATAAGGATTCCTTTTTCGACAGCAAAACCCGGAGCACGATTGTCTATGAGATCTT
GAAGAGAACGACGTGTACAAAGGCCAAGTACAGCATGGGCATCACGAGCCTGCTGGCCAATGGTGTGTACGCGGCTGCATACCCACTGCA
CGATGGAGACTACAACGGTGAAAACGTCGAGTTCAACGACAGAAAACTCCTGTACGAAGAGTGGGCACGCTATGGAGTTTTCTATAAGTA
CCAGCCCATCGACCTGGTCAGGAAGTATTTTGGGGAGAAGATCGGCCTGTACTTCGCCTGGCTGGGCGTGTACACCCAGATGCTCATCCC
TGCCTCCATCGTGGGAATCATTGTCTTCCTGTACGGATGCGCCACCATGGATGAAAACATCCCCAGCATGGAGATGTGTGACCAGAGACA
CAATATCACCATGTGCCCGCTTTGCGACAAGACCTGCAGCTACTGGAAGATGAGCTCAGCCTGCGCCACGGCCCGCGCCAGCCACCTCTT
CGACAACCCCGCCACGGTCTTCTTCTCTGTCTTCATGGCCCTCTGGGCTGCCACCTTCATGGAGCACTGGAAGCGGAAACAGATGCGACT
CAACTACCGCTGGGACCTCACGGGCTTTGAAGAGGAAGAGGATCATCCTAGAGCTGAATACGAAGCCAGAGTCTTGGAGAAGTCTCTGAA
GAAAGAGTCCAGAAACAAAGAGACTGACAAAGTGAAGCTGACATGGAGAGATCGGTTCCCAGCCTACCTCACTAACTTGGTCTCCATCAT
CTTCATGATTGCAGTGACGTTTGCCATCGTCCTCGGCGTCATCATCTACAGAATCTCCATGGCCGCCGCCTTGGCCATGAACTCCTCCCC
CTCCGTGCGGTCCAACATCCGGGTCACAGTCACAGCCACCGCAGTCATCATCAACCTAGTGGTCATCATCCTCCTGGACGAGGTGTATGG
CTGCATAGCCCGATGGCTCACCAAGATCGAGGTCCCAAAGACGGAGAAAAGCTTTGAGGAGAGGCTGATCTTCAAGGCTTTCCTGCTGAA
GTTTGTGAATTCCTACACCCCCATCTTTTACGTGGCGTTCTTCAAAGGCCGGTTTGTTGGACGCCCGGGCGACTACGTGTACATTTTCCG
TTCCTTCCGAATGGAAGAGTGTGCGCCAGGGGGCTGCCTGATGGAGCTATGCATCCAGCTCAGCATCATCATGCTGGGGAAACAGCTGAT
CCAGAACAACCTGTTCGAGATCGGCATCCCGAAGATGAAGAAGCTCATCCGCTACCTGAAGCTGAAGCAGCAGAGCCCCCCTGACCACGA
GGAGTGTGTGAAGAGGAAACAGCGGTACGAGGTGGATTACAACCTGGAGCCCTTCGCGGGCCTCACCCCAGAGTACATGGAAATGATCAT
CCAGTTTGGCTTCGTCACCCTGTTTGTCGCCTCCTTCCCCCTGGCCCCACTGTTTGCGCTGCTGAACAACATCATCGAGATCCGCCTGGA
CGCCAAAAAGTTTGTCACTGAGCTCCGAAGGCCGGTAGCTGTCAGAGCCAAAGACATCGGGAACATCATCGGCTCTGGAATCTTTGTCTC
GCCAAAGGGAGTGCTGGAGAATGCTGGTTCTGTGGGCCTTGCTCTCATCGTCTGGATTGTGACGGGCTTCATCACAGTTGTGGGAGCCCT
CTGCTATGCTGAACTCGGGGTCACCATCCCCAAATCTGGAGGTGACTACTCCTATGTCAAGGACATCTTCGGAGGACTGGCTGGGTTCCT
GAGGCTGTGGATTGCTGTGCTGGTGATCTACCCCACCAACCAGGCTGTCATCGCCCTCACCTTCTCCAACTACGTGCTGCAGCCGCTCTT
CCCCACCTGCTTCCCCCCAGAGTCTGGCCTTCGGCTCCTGGCTGCCATCTGCTTATTGCTCCTCACATGGGTCAACTGTTCCAGTGTGCG
GTGGGCCACCCGGGTTCAAGACATCTTCACAGCTGGGAAGCTCCTGGCCTTGGCCCTGATTATCATCATGGGGATTGTACAGATATGCAA
AGGAGAGTACTTCTGGCTGGAGCCAAAGAATGCATTTGAGAATTTCCAGGAACCTGACATCGGCCTCGTCGCACTGGCTTTCCTTCAGGG
CTCCTTTGCCTATGGAGGCTGGAACTTTCTGAATTACGTGACTGAGGAGCTTGTTGATCCCTACAAGAACCTTCCCAGAGCCATCTTCAT
CTCCATCCCACTGGTCACATTTGTGTATGTCTTTGCCAATGTCGCTTATGTCACTGCAATGTCCCCCCAGGAGCTGCTGGCATCCAACGC
CGTCGCTGTGACTTTTGGAGAGAAGCTCCTAGGAGTCATGGCCTGGATCATGCCCATTTCTGTTGCCCTGTCCACATTTGGAGGAGTTAA
TGGGTCTCTCTTCACCTCCTCTCGGCTGTTCTTCGCTGGAGCCCGAGAGGGCCACCTTCCCAGTGTGTTGGCCATGATCCACGTGAAGCG
CTGCACCCCAATCCCAGCCCTGCTCTTCACATGCATCTCCACCCTGCTGATGCTGGTCACCAGCGACATGTACACACTCATCAACTATGT
GGGCTTCATCAACTACCTCTTCTATGGGGTCACGGTTGCTGGACAGATAGTCCTTCGCTGGAAGAAGCCTGATATCCCCCGCCCCATCAA
GATCAACCTGCTGTTCCCCATCATCTACTTGCTGTTCTGGGCCTTCCTGCTGGTCTTCAGCCTGTGGTCAGAGCCGGTGGTGTGTGGCAT
TGGCCTGGCCATCATGCTGACAGGAGTGCCTGTCTATTTCCTGGGTGTTTACTGGCAACACAAGCCCAAGTGTTTCAGTGACTTCATTGA
GCTGCTAACCCTGGTGAGCCAGAAGATGTGTGTGGTCGTGTACCCCGAGGTGGAGCGGGGCTCAGGGACAGAGGAGGCTAATGAGGACAT
GGAGGAGCAGCAGCAGCCCATGTACCAACCCACTCCCACGAAGGACAAGGACGTGGCGGGGCAGCCCCAGCCCTGAGGACCACCATTCCC
TGGCTACTCTCTCCTTCCTCCCCCTTTTATCCTACCTCCCTGCCTTGGTCCTGCCAACACATGCGAGTACACACACACCCCTCTCTCTGC
TTTTGTCAGGCAGTGGTAGGACTTTGGTGTGGGTGGTGAGAAATTGTAAACAAAAACTGACATTCATACCCAAAGAACCAGCCTCTCACC
CCAGGGTCCATGTCCCAGGCCCCACTCCAGTGCTGCCCACACTCCCAGCTGCTGGAGGAGAGGGGAGATGCCAAGGTGCCCTGCAGGACC
TCCCTCCGGGCCACACCCTCAGCTGCCTCTTCAGGAACCGGAGCTCATTACTGCCTTCCCTCCCAGGGAGGCCCCTTCAGAGAGGAGAGG
CCACAGGAGCTGCATTGTGGGGGGACAGGCTCAAGCAATTCTGTCCCCATCAAGGGGTCAGCTGGAGAGACCCAAGACCCTATCTGTTCA
CCAGGGACCCAAAATCCAAGGGGATGCTTCCCTCTGCCCTCTTTCCTGCCCCTCCCCATCATACCTGCACCCACCCCAGCCAGGGCTCCC
TGTCCAGAATTCGGTTCTCCTCAGGACGCCAACTCCCAGAGCTAAGGACCAAGGAGAAGAACAGCCTCTCCACCCCCAAGCCAGGCGGTT
GAGGAACATATTGAGAAAGGTTCAGATTGCAGAAACCCAGCCCTGCCCCTGCCTCCTGCATCCAGCCCCCAACATGGTGCCAAAGCTTCC
AGAAGCCAAAAAGCTTCTGATTTTTAAGGTAGTGGGCATCTCTCTCCTAATGACGAAGCTGCTCAGCAACTCCACCTGCCCGCCGCAGGA
AGGAGCAGTCCCCTGCTATCCCTGCAGCCACTCCCAGCACACCCGCACACAGCCAGCACCACCGCCCCCACCGTGCACTTCTCCTCTCTG
GGCCTTGGCTTGGGACCAGGTACGAAGGATCCCCAAGCCCTTCAGGCCTGAGATCAGAGCCAGATCAGCCTTAAGTCACCTCCCATCCAA
GAACTTGGCCTAAAAATACTCCCCTATTTCTAACCCTCAGGACGGATCTGATATTAAATGCCTTCCCTGGGAGGAAGGGTGCTTTCCCCC
TCCCTAGAGGTGCCCATTCCATACCCTGGGAGACTGAGGAGAGCATTGGCTGAAGCCCAGTTCCTTTCCCATCCATCCCCAACTCCAATA
ATCCCCCACTCCTCGCAGGTCTCAGTGTCATGCTGTCTTGGGGCAGGGTGAAAGGGTAGTGGCAGCAGGGCGCCCACTCTGGAGATCCTC
AAAAAAGGCCCTCCTCTGTGGCTGGCAGCCTCTGACCTTTCCCTGGGCTTCAAAGGAAGGCTATGGAGTTTGCTGTGGGCCCTGCAACCT
TCCCAGCCACTCCTGCTGCACTAAGGACTTAGGATCCTTTTATCACAAATCGGGATTCTCTCCCCCACCCCGAATTCTGTCTGCTTAAAC
TGGAATACACAGGAGCCCTTCCTGGCCTGGATGGTGTCTCCCAGCTTCCCCGCCCAGCTTGCCCACCCCATAGTTGGTGAGATGCCAAGT
TTGGTCTGAGTTGTGACCCCTTCAGAGTAGATGCCCGGCAGGCTGGGGTTGGCCCCTGGAGGGTCAGGGGACCATCTTCTTATTCCCTCT
TTTCTCATTCCTCCAACTTCCTCCCCTCCTTCAATTATTTTTTTGTAAAGTTGATGCCTTACTTTTTGGATAAATATTTTTGAAGCTGGT
ATTTCTATTTCTTTTGGATTTTTTTTAATGTAAGGTTGTTTTGGGGGATGGAGTTAGAACCTTAATGATAATTTCTTTCGTTTGGTGTAG

>4864_4864_3_ANO1-SLC7A8_ANO1_chr11_70017145_ENST00000398543_SLC7A8_chr14_23635749_ENST00000316902_length(amino acids)=1238AA_BP=753
MRVNEKYSTLPAEDRSVHIINICAIEDIGYLPSEGTLLNSLSVDPDAECKYGLYFRDGRRKVDYILVYHHKRPSGNRTLVRRVQHSDTPS
GARSVKQDHPLPGKGASLDAGSGEPPMDYHEDDKRFRREEYEGNLLEAGLELERDEDTKIHGVGFVKIHAPWNVLCREAEFLKLKMPTKK
MYHINETRGLLKKINSVLQKITDPIQPKVAEHRPQTMKRLSYPFSREKQHLFDLSDKDSFFDSKTRSTIVYEILKRTTCTKAKYSMGITS
LLANGVYAAAYPLHDGDYNGENVEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEKIGLYFAWLGVYTQMLIPASIVGIIVFLYGCATM
DENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMALWAATFMEHWKRKQMRLNYRWDLTGFEEEEDHP
RAEYEARVLEKSLKKESRNKETDKVKLTWRDRFPAYLTNLVSIIFMIAVTFAIVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATAVI
INLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLMEL
CIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECVKRKQRYEVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAP
LFALLNNIIEIRLDAKKFVTELRRPVAVRAKDIGNIIGSGIFVSPKGVLENAGSVGLALIVWIVTGFITVVGALCYAELGVTIPKSGGDY
SYVKDIFGGLAGFLRLWIAVLVIYPTNQAVIALTFSNYVLQPLFPTCFPPESGLRLLAAICLLLLTWVNCSSVRWATRVQDIFTAGKLLA
LALIIIMGIVQICKGEYFWLEPKNAFENFQEPDIGLVALAFLQGSFAYGGWNFLNYVTEELVDPYKNLPRAIFISIPLVTFVYVFANVAY
VTAMSPQELLASNAVAVTFGEKLLGVMAWIMPISVALSTFGGVNGSLFTSSRLFFAGAREGHLPSVLAMIHVKRCTPIPALLFTCISTLL
MLVTSDMYTLINYVGFINYLFYGVTVAGQIVLRWKKPDIPRPIKINLLFPIIYLLFWAFLLVFSLWSEPVVCGIGLAIMLTGVPVYFLGV

--------------------------------------------------------------
>4864_4864_4_ANO1-SLC7A8_ANO1_chr11_70017145_ENST00000398543_SLC7A8_chr14_23635749_ENST00000469263_length(transcript)=4988nt_BP=2309nt
GGATGGGGAGGGCGCGCCGCCCGGCGGTCCCAGCGCACAGGCGGCCACGATGAGGGTCAACGAGAAGTACTCGACGCTCCCGGCCGAGGA
CCGCAGCGTCCACATCATCAACATCTGCGCCATCGAGGACATCGGCTACCTGCCGTCCGAGGGCACGCTGCTGAACTCCTTATCTGTGGA
CCCTGATGCCGAGTGCAAGTATGGCCTGTACTTCAGGGACGGCCGGCGCAAGGTGGACTACATCCTGGTGTACCATCACAAGAGGCCCTC
GGGCAACCGGACCCTGGTCAGGAGGGTGCAGCACAGCGACACCCCCTCTGGGGCTCGCAGCGTCAAGCAGGACCACCCCCTGCCGGGCAA
GGGGGCGTCGCTGGATGCAGGCTCGGGGGAGCCCCCGATGGACTACCACGAGGATGACAAGCGCTTCCGCAGGGAGGAGTACGAGGGCAA
CCTCCTGGAGGCGGGCCTGGAGCTGGAGCGGGACGAGGACACTAAAATCCACGGAGTCGGGTTTGTGAAAATCCATGCCCCCTGGAACGT
GCTGTGCAGAGAGGCCGAGTTTCTGAAACTGAAGATGCCGACGAAGAAGATGTACCACATTAATGAGACCCGTGGCCTCCTGAAAAAAAT
CAACTCTGTGCTCCAGAAAATCACAGATCCCATCCAGCCCAAAGTGGCTGAGCACAGGCCCCAGACCATGAAGAGACTCTCCTATCCCTT
CTCCCGGGAGAAGCAGCATCTATTTGACTTGTCTGATAAGGATTCCTTTTTCGACAGCAAAACCCGGAGCACGATTGTCTATGAGATCTT
GAAGAGAACGACGTGTACAAAGGCCAAGTACAGCATGGGCATCACGAGCCTGCTGGCCAATGGTGTGTACGCGGCTGCATACCCACTGCA
CGATGGAGACTACAACGGTGAAAACGTCGAGTTCAACGACAGAAAACTCCTGTACGAAGAGTGGGCACGCTATGGAGTTTTCTATAAGTA
CCAGCCCATCGACCTGGTCAGGAAGTATTTTGGGGAGAAGATCGGCCTGTACTTCGCCTGGCTGGGCGTGTACACCCAGATGCTCATCCC
TGCCTCCATCGTGGGAATCATTGTCTTCCTGTACGGATGCGCCACCATGGATGAAAACATCCCCAGCATGGAGATGTGTGACCAGAGACA
CAATATCACCATGTGCCCGCTTTGCGACAAGACCTGCAGCTACTGGAAGATGAGCTCAGCCTGCGCCACGGCCCGCGCCAGCCACCTCTT
CGACAACCCCGCCACGGTCTTCTTCTCTGTCTTCATGGCCCTCTGGGCTGCCACCTTCATGGAGCACTGGAAGCGGAAACAGATGCGACT
CAACTACCGCTGGGACCTCACGGGCTTTGAAGAGGAAGAGGATCATCCTAGAGCTGAATACGAAGCCAGAGTCTTGGAGAAGTCTCTGAA
GAAAGAGTCCAGAAACAAAGAGACTGACAAAGTGAAGCTGACATGGAGAGATCGGTTCCCAGCCTACCTCACTAACTTGGTCTCCATCAT
CTTCATGATTGCAGTGACGTTTGCCATCGTCCTCGGCGTCATCATCTACAGAATCTCCATGGCCGCCGCCTTGGCCATGAACTCCTCCCC
CTCCGTGCGGTCCAACATCCGGGTCACAGTCACAGCCACCGCAGTCATCATCAACCTAGTGGTCATCATCCTCCTGGACGAGGTGTATGG
CTGCATAGCCCGATGGCTCACCAAGATCGAGGTCCCAAAGACGGAGAAAAGCTTTGAGGAGAGGCTGATCTTCAAGGCTTTCCTGCTGAA
GTTTGTGAATTCCTACACCCCCATCTTTTACGTGGCGTTCTTCAAAGGCCGGTTTGTTGGACGCCCGGGCGACTACGTGTACATTTTCCG
TTCCTTCCGAATGGAAGAGTGTGCGCCAGGGGGCTGCCTGATGGAGCTATGCATCCAGCTCAGCATCATCATGCTGGGGAAACAGCTGAT
CCAGAACAACCTGTTCGAGATCGGCATCCCGAAGATGAAGAAGCTCATCCGCTACCTGAAGCTGAAGCAGCAGAGCCCCCCTGACCACGA
GGAGTGTGTGAAGAGGAAACAGCGGTACGAGGTGGATTACAACCTGGAGCCCTTCGCGGGCCTCACCCCAGAGTACATGGAAATGATCAT
CCAGTTTGGCTTCGTCACCCTGTTTGTCGCCTCCTTCCCCCTGGCCCCACTGTTTGCGCTGCTGAACAACATCATCGAGATCCGCCTGGA
CGCCAAAAAGTTTGTCACTGAGCTCCGAAGGCCGGTAGCTGTCAGAGCCAAAGACATCGGGAACATCATCGGCTCTGGAATCTTTGTCTC
GCCAAAGGGAGTGCTGGAGAATGCTGGTTCTGTGGGCCTTGCTCTCATCGTCTGGATTGTGACGGGCTTCATCACAGTTGTGGGAGCCCT
CTGCTATGCTGAACTCGGGGTCACCATCCCCAAATCTGGAGGTGACTACTCCTATGTCAAGGACATCTTCGGAGGACTGGCTGGGTTCCT
GAGGCTGTGGATTGCTGTGCTGGTGATCTACCCCACCAACCAGGCTGTCATCGCCCTCACCTTCTCCAACTACGTGCTGCAGCCGCTCTT
CCCCACCTGCTTCCCCCCAGAGTCTGGCCTTCGGCTCCTGGCTGCCATCTGCTTATTGCTCCTCACATGGGTCAACTGTTCCAGTGTGCG
GTGGGCCACCCGGGTTCAAGACATCTTCACAGCTGGGAAGCTCCTGGCCTTGGCCCTGATTATCATCATGGGGATTGTACAGATATGCAA
AGGAGAGTACTTCTGGCTGGAGCCAAAGAATGCATTTGAGAATTTCCAGGAACCTGACATCGGCCTCGTCGCACTGGCTTTCCTTCAGGG
CTCCTTTGCCTATGGAGGCTGGAACTTTCTGAATTACGTGACTGAGGAGCTTGTTGATCCCTACAAAGCTGCTAACCCTGGTGAGCCAGA
AGATGTGTGTGGTCGTGTACCCCGAGGTGGAGCGGGGCTCAGGGACAGAGGAGGCTAATGAGGACATGGAGGAGCAGCAGCAGCCCATGT
ACCAACCCACTCCCACGAAGGACAAGGACGTGGCGGGGCAGCCCCAGCCCTGAGGACCACCATTCCCTGGCTACTCTCTCCTTCCTCCCC
CTTTTATCCTACCTCCCTGCCTTGGTCCTGCCAACACATGCGAGTACACACACACCCCTCTCTCTGCTTTTGTCAGGCAGTGGTAGGACT
TTGGTGTGGGTGGTGAGAAATTGTAAACAAAAACTGACATTCATACCCAAAGAACCAGCCTCTCACCCCAGGGTCCATGTCCCAGGCCCC
ACTCCAGTGCTGCCCACACTCCCAGCTGCTGGAGGAGAGGGGAGATGCCAAGGTGCCCTGCAGGACCTCCCTCCGGGCCACACCCTCAGC
TGCCTCTTCAGGAACCGGAGCTCATTACTGCCTTCCCTCCCAGGGAGGCCCCTTCAGAGAGGAGAGGCCACAGGAGCTGCATTGTGGGGG
GACAGGCTCAAGCAATTCTGTCCCCATCAAGGGGTCAGCTGGAGAGACCCAAGACCCTATCTGTTCACCAGGGACCCAAAATCCAAGGGG
ATGCTTCCCTCTGCCCTCTTTCCTGCCCCTCCCCATCATACCTGCACCCACCCCAGCCAGGGCTCCCTGTCCAGAATTCGGTTCTCCTCA
GGACGCCAACTCCCAGAGCTAAGGACCAAGGAGAAGAACAGCCTCTCCACCCCCAAGCCAGGCGGTTGAGGAACATATTGAGAAAGGTTC
AGATTGCAGAAACCCAGCCCTGCCCCTGCCTCCTGCATCCAGCCCCCAACATGGTGCCAAAGCTTCCAGAAGCCAAAAAGCTTCTGATTT
TTAAGGTAGTGGGCATCTCTCTCCTAATGACGAAGCTGCTCAGCAACTCCACCTGCCCGCCGCAGGAAGGAGCAGTCCCCTGCTATCCCT
GCAGCCACTCCCAGCACACCCGCACACAGCCAGCACCACCGCCCCCACCGTGCACTTCTCCTCTCTGGGCCTTGGCTTGGGACCAGGTAC
GAAGGATCCCCAAGCCCTTCAGGCCTGAGATCAGAGCCAGATCAGCCTTAAGTCACCTCCCATCCAAGAACTTGGCCTAAAAATACTCCC
CTATTTCTAACCCTCAGGACGGATCTGATATTAAATGCCTTCCCTGGGAGGAAGGGTGCTTTCCCCCTCCCTAGAGGTGCCCATTCCATA
CCCTGGGAGACTGAGGAGAGCATTGGCTGAAGCCCAGTTCCTTTCCCATCCATCCCCAACTCCAATAATCCCCCACTCCTCGCAGGTCTC
AGTGTCATGCTGTCTTGGGGCAGGGTGAAAGGGTAGTGGCAGCAGGGCGCCCACTCTGGAGATCCTCAAAAAAGGCCCTCCTCTGTGGCT
GGCAGCCTCTGACCTTTCCCTGGGCTTCAAAGGAAGGCTATGGAGTTTGCTGTGGGCCCTGCAACCTTCCCAGCCACTCCTGCTGCACTA
AGGACTTAGGATCCTTTTATCACAAATCGGGATTCTCTCCCCCACCCCGAATTCTGTCTGCTTAAACTGGAATACACAGGAGCCCTTCCT
GGCCTGGATGGTGTCTCCCAGCTTCCCCGCCCAGCTTGCCCACCCCATAGTTGGTGAGATGCCAAGTTTGGTCTGAGTTGTGACCCCTTC
AGAGTAGATGCCCGGCAGGCTGGGGTTGGCCCCTGGAGGGTCAGGGGACCATCTTCTTATTCCCTCTTTTCTCATTCCTCCAACTTCCTC
CCCTCCTTCAATTATTTTTTTGTAAAGTTGATGCCTTACTTTTTGGATAAATATTTTTGAAGCTGGTATTTCTATTTCTTTTGGATTTTT
TTTAATGTAAGGTTGTTTTGGGGGATGGAGTTAGAACCTTAATGATAATTTCTTTCGTTTGGTGTAGGTTTTAGAGATTTGTTTTGTGGA

>4864_4864_4_ANO1-SLC7A8_ANO1_chr11_70017145_ENST00000398543_SLC7A8_chr14_23635749_ENST00000469263_length(amino acids)=992AA_BP=753
MRVNEKYSTLPAEDRSVHIINICAIEDIGYLPSEGTLLNSLSVDPDAECKYGLYFRDGRRKVDYILVYHHKRPSGNRTLVRRVQHSDTPS
GARSVKQDHPLPGKGASLDAGSGEPPMDYHEDDKRFRREEYEGNLLEAGLELERDEDTKIHGVGFVKIHAPWNVLCREAEFLKLKMPTKK
MYHINETRGLLKKINSVLQKITDPIQPKVAEHRPQTMKRLSYPFSREKQHLFDLSDKDSFFDSKTRSTIVYEILKRTTCTKAKYSMGITS
LLANGVYAAAYPLHDGDYNGENVEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEKIGLYFAWLGVYTQMLIPASIVGIIVFLYGCATM
DENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMALWAATFMEHWKRKQMRLNYRWDLTGFEEEEDHP
RAEYEARVLEKSLKKESRNKETDKVKLTWRDRFPAYLTNLVSIIFMIAVTFAIVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATAVI
INLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLMEL
CIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECVKRKQRYEVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAP
LFALLNNIIEIRLDAKKFVTELRRPVAVRAKDIGNIIGSGIFVSPKGVLENAGSVGLALIVWIVTGFITVVGALCYAELGVTIPKSGGDY
SYVKDIFGGLAGFLRLWIAVLVIYPTNQAVIALTFSNYVLQPLFPTCFPPESGLRLLAAICLLLLTWVNCSSVRWATRVQDIFTAGKLLA
LALIIIMGIVQICKGEYFWLEPKNAFENFQEPDIGLVALAFLQGSFAYGGWNFLNYVTEELVDPYKAANPGEPEDVCGRVPRGGAGLRDR

--------------------------------------------------------------
>4864_4864_5_ANO1-SLC7A8_ANO1_chr11_70017145_ENST00000530676_SLC7A8_chr14_23635749_ENST00000316902_length(transcript)=5740nt_BP=2401nt
TGAGTCCAGGTCCTCCTGAAGGTCACCAGCACAGCGGGGCCCTGTGTTACTGTAGAGAGAAGTCAGTTGCTTAGTTTCAGCCTCCTGCCG
GCACCAGATGCTGACCAGGCCCTCCCAGGTGGTGAGCAATGCTGTTTCCAGGAGAGGCATCCTAGGGCCAGAGAGGCCAAGGTGCCAGGG
ACATGGCCCCAACTGTCCCCTAACCAGGGGTAGAGGAGTCTAGACCCTTGACATCAACACCTATGAAAGCTGCTGAACTCCTTATCTGTG
GACCCTGATGCCGAGTGCAAGTATGGCCTGTACTTCAGGGACGGCCGGCGCAAGGTGGACTACATCCTGGTGTACCATCACAAGAGGCCC
TCGGGCAACCGGACCCTGGTCAGGAGGGTGCAGCACAGCGACACCCCCTCTGGGGCTCGCAGCGTCAAGCAGGACCACCCCCTGCCGGGC
AAGGGGGCGTCGCTGGATGCAGGCTCGGGGGAGCCCCCGATGGACTACCACGAGGATGACAAGCGCTTCCGCAGGGAGGAGTACGAGGGC
AACCTCCTGGAGGCGGGCCTGGAGCTGGAGCGGGACGAGGACACTAAAATCCACGGAGTCGGGTTTGTGAAAATCCATGCCCCCTGGAAC
GTGCTGTGCAGAGAGGCCGAGTTTCTGAAACTGAAGATGCCGACGAAGAAGATGTACCACATTAATGAGACCCGTGGCCTCCTGAAAAAA
ATCAACTCTGTGCTCCAGAAAATCACAGATCCCATCCAGCCCAAAGTGGCTGAGCACAGGCCCCAGACCATGAAGAGACTCTCCTATCCC
TTCTCCCGGGAGAAGCAGCATCTATTTGACTTGTCTGATAAGGATTCCTTTTTCGACAGCAAAACCCGGAGCACGATTGTCTATGAGATC
TTGAAGAGAACGACGTGTACAAAGGCCAAGTACAGCATGGGCATCACGAGCCTGCTGGCCAATGGTGTGTACGCGGCTGCATACCCACTG
CACGATGGAGACTACAACGGTGAAAACGTCGAGTTCAACGACAGAAAACTCCTGTACGAAGAGTGGGCACGCTATGGAGTTTTCTATAAG
TACCAGCCCATCGACCTGGTCAGGAAGTATTTTGGGGAGAAGATCGGCCTGTACTTCGCCTGGCTGGGCGTGTACACCCAGATGCTCATC
CCTGCCTCCATCGTGGGAATCATTGTCTTCCTGTACGGATGCGCCACCATGGATGAAAACATCCCCAGCATGGAGATGTGTGACCAGAGA
CACAATATCACCATGTGCCCGCTTTGCGACAAGACCTGCAGCTACTGGAAGATGAGCTCAGCCTGCGCCACGGCCCGCGCCAGCCACCTC
TTCGACAACCCCGCCACGGTCTTCTTCTCTGTCTTCATGGCCCTCTGGGCTGCCACCTTCATGGAGCACTGGAAGCGGAAACAGATGCGA
CTCAACTACCGCTGGGACCTCACGGGCTTTGAAGAGGAAGAGGATCATCCTAGAGCTGAATACGAAGCCAGAGTCTTGGAGAAGTCTCTG
AAGAAAGAGTCCAGAAACAAAGAGACTGACAAAGTGAAGCTGACATGGAGAGATCGGTTCCCAGCCTACCTCACTAACTTGGTCTCCATC
ATCTTCATGATTGCAGTGACGTTTGCCATCGTCCTCGGCGTCATCATCTACAGAATCTCCATGGCCGCCGCCTTGGCCATGAACTCCTCC
CCCTCCGTGCGGTCCAACATCCGGGTCACAGTCACAGCCACCGCAGTCATCATCAACCTAGTGGTCATCATCCTCCTGGACGAGGTGTAT
GGCTGCATAGCCCGATGGCTCACCAAGATCGAGGTCCCAAAGACGGAGAAAAGCTTTGAGGAGAGGCTGATCTTCAAGGCTTTCCTGCTG
AAGTTTGTGAATTCCTACACCCCCATCTTTTACGTGGCGTTCTTCAAAGGCCGGTTTGTTGGACGCCCGGGCGACTACGTGTACATTTTC
CGTTCCTTCCGAATGGAAGAGTGTGCGCCAGGGGGCTGCCTGATGGAGCTATGCATCCAGCTCAGCATCATCATGCTGGGGAAACAGCTG
ATCCAGAACAACCTGTTCGAGATCGGCATCCCGAAGATGAAGAAGCTCATCCGCTACCTGAAGCTGAAGCAGCAGAGCCCCCCTGACCAC
GAGGAGTGTGTGAAGAGGAAACAGCGGTACGAGGTGGATTACAACCTGGAGCCCTTCGCGGGCCTCACCCCAGAGTACATGGAAATGATC
ATCCAGTTTGGCTTCGTCACCCTGTTTGTCGCCTCCTTCCCCCTGGCCCCACTGTTTGCGCTGCTGAACAACATCATCGAGATCCGCCTG
GACGCCAAAAAGTTTGTCACTGAGCTCCGAAGGCCGGTAGCTGTCAGAGCCAAAGACATCGGGAACATCATCGGCTCTGGAATCTTTGTC
TCGCCAAAGGGAGTGCTGGAGAATGCTGGTTCTGTGGGCCTTGCTCTCATCGTCTGGATTGTGACGGGCTTCATCACAGTTGTGGGAGCC
CTCTGCTATGCTGAACTCGGGGTCACCATCCCCAAATCTGGAGGTGACTACTCCTATGTCAAGGACATCTTCGGAGGACTGGCTGGGTTC
CTGAGGCTGTGGATTGCTGTGCTGGTGATCTACCCCACCAACCAGGCTGTCATCGCCCTCACCTTCTCCAACTACGTGCTGCAGCCGCTC
TTCCCCACCTGCTTCCCCCCAGAGTCTGGCCTTCGGCTCCTGGCTGCCATCTGCTTATTGCTCCTCACATGGGTCAACTGTTCCAGTGTG
CGGTGGGCCACCCGGGTTCAAGACATCTTCACAGCTGGGAAGCTCCTGGCCTTGGCCCTGATTATCATCATGGGGATTGTACAGATATGC
AAAGGAGAGTACTTCTGGCTGGAGCCAAAGAATGCATTTGAGAATTTCCAGGAACCTGACATCGGCCTCGTCGCACTGGCTTTCCTTCAG
GGCTCCTTTGCCTATGGAGGCTGGAACTTTCTGAATTACGTGACTGAGGAGCTTGTTGATCCCTACAAGAACCTTCCCAGAGCCATCTTC
ATCTCCATCCCACTGGTCACATTTGTGTATGTCTTTGCCAATGTCGCTTATGTCACTGCAATGTCCCCCCAGGAGCTGCTGGCATCCAAC
GCCGTCGCTGTGACTTTTGGAGAGAAGCTCCTAGGAGTCATGGCCTGGATCATGCCCATTTCTGTTGCCCTGTCCACATTTGGAGGAGTT
AATGGGTCTCTCTTCACCTCCTCTCGGCTGTTCTTCGCTGGAGCCCGAGAGGGCCACCTTCCCAGTGTGTTGGCCATGATCCACGTGAAG
CGCTGCACCCCAATCCCAGCCCTGCTCTTCACATGCATCTCCACCCTGCTGATGCTGGTCACCAGCGACATGTACACACTCATCAACTAT
GTGGGCTTCATCAACTACCTCTTCTATGGGGTCACGGTTGCTGGACAGATAGTCCTTCGCTGGAAGAAGCCTGATATCCCCCGCCCCATC
AAGATCAACCTGCTGTTCCCCATCATCTACTTGCTGTTCTGGGCCTTCCTGCTGGTCTTCAGCCTGTGGTCAGAGCCGGTGGTGTGTGGC
ATTGGCCTGGCCATCATGCTGACAGGAGTGCCTGTCTATTTCCTGGGTGTTTACTGGCAACACAAGCCCAAGTGTTTCAGTGACTTCATT
GAGCTGCTAACCCTGGTGAGCCAGAAGATGTGTGTGGTCGTGTACCCCGAGGTGGAGCGGGGCTCAGGGACAGAGGAGGCTAATGAGGAC
ATGGAGGAGCAGCAGCAGCCCATGTACCAACCCACTCCCACGAAGGACAAGGACGTGGCGGGGCAGCCCCAGCCCTGAGGACCACCATTC
CCTGGCTACTCTCTCCTTCCTCCCCCTTTTATCCTACCTCCCTGCCTTGGTCCTGCCAACACATGCGAGTACACACACACCCCTCTCTCT
GCTTTTGTCAGGCAGTGGTAGGACTTTGGTGTGGGTGGTGAGAAATTGTAAACAAAAACTGACATTCATACCCAAAGAACCAGCCTCTCA
CCCCAGGGTCCATGTCCCAGGCCCCACTCCAGTGCTGCCCACACTCCCAGCTGCTGGAGGAGAGGGGAGATGCCAAGGTGCCCTGCAGGA
CCTCCCTCCGGGCCACACCCTCAGCTGCCTCTTCAGGAACCGGAGCTCATTACTGCCTTCCCTCCCAGGGAGGCCCCTTCAGAGAGGAGA
GGCCACAGGAGCTGCATTGTGGGGGGACAGGCTCAAGCAATTCTGTCCCCATCAAGGGGTCAGCTGGAGAGACCCAAGACCCTATCTGTT
CACCAGGGACCCAAAATCCAAGGGGATGCTTCCCTCTGCCCTCTTTCCTGCCCCTCCCCATCATACCTGCACCCACCCCAGCCAGGGCTC
CCTGTCCAGAATTCGGTTCTCCTCAGGACGCCAACTCCCAGAGCTAAGGACCAAGGAGAAGAACAGCCTCTCCACCCCCAAGCCAGGCGG
TTGAGGAACATATTGAGAAAGGTTCAGATTGCAGAAACCCAGCCCTGCCCCTGCCTCCTGCATCCAGCCCCCAACATGGTGCCAAAGCTT
CCAGAAGCCAAAAAGCTTCTGATTTTTAAGGTAGTGGGCATCTCTCTCCTAATGACGAAGCTGCTCAGCAACTCCACCTGCCCGCCGCAG
GAAGGAGCAGTCCCCTGCTATCCCTGCAGCCACTCCCAGCACACCCGCACACAGCCAGCACCACCGCCCCCACCGTGCACTTCTCCTCTC
TGGGCCTTGGCTTGGGACCAGGTACGAAGGATCCCCAAGCCCTTCAGGCCTGAGATCAGAGCCAGATCAGCCTTAAGTCACCTCCCATCC
AAGAACTTGGCCTAAAAATACTCCCCTATTTCTAACCCTCAGGACGGATCTGATATTAAATGCCTTCCCTGGGAGGAAGGGTGCTTTCCC
CCTCCCTAGAGGTGCCCATTCCATACCCTGGGAGACTGAGGAGAGCATTGGCTGAAGCCCAGTTCCTTTCCCATCCATCCCCAACTCCAA
TAATCCCCCACTCCTCGCAGGTCTCAGTGTCATGCTGTCTTGGGGCAGGGTGAAAGGGTAGTGGCAGCAGGGCGCCCACTCTGGAGATCC
TCAAAAAAGGCCCTCCTCTGTGGCTGGCAGCCTCTGACCTTTCCCTGGGCTTCAAAGGAAGGCTATGGAGTTTGCTGTGGGCCCTGCAAC
CTTCCCAGCCACTCCTGCTGCACTAAGGACTTAGGATCCTTTTATCACAAATCGGGATTCTCTCCCCCACCCCGAATTCTGTCTGCTTAA
ACTGGAATACACAGGAGCCCTTCCTGGCCTGGATGGTGTCTCCCAGCTTCCCCGCCCAGCTTGCCCACCCCATAGTTGGTGAGATGCCAA
GTTTGGTCTGAGTTGTGACCCCTTCAGAGTAGATGCCCGGCAGGCTGGGGTTGGCCCCTGGAGGGTCAGGGGACCATCTTCTTATTCCCT
CTTTTCTCATTCCTCCAACTTCCTCCCCTCCTTCAATTATTTTTTTGTAAAGTTGATGCCTTACTTTTTGGATAAATATTTTTGAAGCTG
GTATTTCTATTTCTTTTGGATTTTTTTTAATGTAAGGTTGTTTTGGGGGATGGAGTTAGAACCTTAATGATAATTTCTTTCGTTTGGTGT

>4864_4864_5_ANO1-SLC7A8_ANO1_chr11_70017145_ENST00000530676_SLC7A8_chr14_23635749_ENST00000316902_length(amino acids)=1202AA_BP=717
MLNSLSVDPDAECKYGLYFRDGRRKVDYILVYHHKRPSGNRTLVRRVQHSDTPSGARSVKQDHPLPGKGASLDAGSGEPPMDYHEDDKRF
RREEYEGNLLEAGLELERDEDTKIHGVGFVKIHAPWNVLCREAEFLKLKMPTKKMYHINETRGLLKKINSVLQKITDPIQPKVAEHRPQT
MKRLSYPFSREKQHLFDLSDKDSFFDSKTRSTIVYEILKRTTCTKAKYSMGITSLLANGVYAAAYPLHDGDYNGENVEFNDRKLLYEEWA
RYGVFYKYQPIDLVRKYFGEKIGLYFAWLGVYTQMLIPASIVGIIVFLYGCATMDENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACA
TARASHLFDNPATVFFSVFMALWAATFMEHWKRKQMRLNYRWDLTGFEEEEDHPRAEYEARVLEKSLKKESRNKETDKVKLTWRDRFPAY
LTNLVSIIFMIAVTFAIVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERL
IFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLK
QQSPPDHEECVKRKQRYEVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAVRAKDIGNI
IGSGIFVSPKGVLENAGSVGLALIVWIVTGFITVVGALCYAELGVTIPKSGGDYSYVKDIFGGLAGFLRLWIAVLVIYPTNQAVIALTFS
NYVLQPLFPTCFPPESGLRLLAAICLLLLTWVNCSSVRWATRVQDIFTAGKLLALALIIIMGIVQICKGEYFWLEPKNAFENFQEPDIGL
VALAFLQGSFAYGGWNFLNYVTEELVDPYKNLPRAIFISIPLVTFVYVFANVAYVTAMSPQELLASNAVAVTFGEKLLGVMAWIMPISVA
LSTFGGVNGSLFTSSRLFFAGAREGHLPSVLAMIHVKRCTPIPALLFTCISTLLMLVTSDMYTLINYVGFINYLFYGVTVAGQIVLRWKK
PDIPRPIKINLLFPIIYLLFWAFLLVFSLWSEPVVCGIGLAIMLTGVPVYFLGVYWQHKPKCFSDFIELLTLVSQKMCVVVYPEVERGSG

--------------------------------------------------------------
>4864_4864_6_ANO1-SLC7A8_ANO1_chr11_70017145_ENST00000530676_SLC7A8_chr14_23635749_ENST00000469263_length(transcript)=5080nt_BP=2401nt
TGAGTCCAGGTCCTCCTGAAGGTCACCAGCACAGCGGGGCCCTGTGTTACTGTAGAGAGAAGTCAGTTGCTTAGTTTCAGCCTCCTGCCG
GCACCAGATGCTGACCAGGCCCTCCCAGGTGGTGAGCAATGCTGTTTCCAGGAGAGGCATCCTAGGGCCAGAGAGGCCAAGGTGCCAGGG
ACATGGCCCCAACTGTCCCCTAACCAGGGGTAGAGGAGTCTAGACCCTTGACATCAACACCTATGAAAGCTGCTGAACTCCTTATCTGTG
GACCCTGATGCCGAGTGCAAGTATGGCCTGTACTTCAGGGACGGCCGGCGCAAGGTGGACTACATCCTGGTGTACCATCACAAGAGGCCC
TCGGGCAACCGGACCCTGGTCAGGAGGGTGCAGCACAGCGACACCCCCTCTGGGGCTCGCAGCGTCAAGCAGGACCACCCCCTGCCGGGC
AAGGGGGCGTCGCTGGATGCAGGCTCGGGGGAGCCCCCGATGGACTACCACGAGGATGACAAGCGCTTCCGCAGGGAGGAGTACGAGGGC
AACCTCCTGGAGGCGGGCCTGGAGCTGGAGCGGGACGAGGACACTAAAATCCACGGAGTCGGGTTTGTGAAAATCCATGCCCCCTGGAAC
GTGCTGTGCAGAGAGGCCGAGTTTCTGAAACTGAAGATGCCGACGAAGAAGATGTACCACATTAATGAGACCCGTGGCCTCCTGAAAAAA
ATCAACTCTGTGCTCCAGAAAATCACAGATCCCATCCAGCCCAAAGTGGCTGAGCACAGGCCCCAGACCATGAAGAGACTCTCCTATCCC
TTCTCCCGGGAGAAGCAGCATCTATTTGACTTGTCTGATAAGGATTCCTTTTTCGACAGCAAAACCCGGAGCACGATTGTCTATGAGATC
TTGAAGAGAACGACGTGTACAAAGGCCAAGTACAGCATGGGCATCACGAGCCTGCTGGCCAATGGTGTGTACGCGGCTGCATACCCACTG
CACGATGGAGACTACAACGGTGAAAACGTCGAGTTCAACGACAGAAAACTCCTGTACGAAGAGTGGGCACGCTATGGAGTTTTCTATAAG
TACCAGCCCATCGACCTGGTCAGGAAGTATTTTGGGGAGAAGATCGGCCTGTACTTCGCCTGGCTGGGCGTGTACACCCAGATGCTCATC
CCTGCCTCCATCGTGGGAATCATTGTCTTCCTGTACGGATGCGCCACCATGGATGAAAACATCCCCAGCATGGAGATGTGTGACCAGAGA
CACAATATCACCATGTGCCCGCTTTGCGACAAGACCTGCAGCTACTGGAAGATGAGCTCAGCCTGCGCCACGGCCCGCGCCAGCCACCTC
TTCGACAACCCCGCCACGGTCTTCTTCTCTGTCTTCATGGCCCTCTGGGCTGCCACCTTCATGGAGCACTGGAAGCGGAAACAGATGCGA
CTCAACTACCGCTGGGACCTCACGGGCTTTGAAGAGGAAGAGGATCATCCTAGAGCTGAATACGAAGCCAGAGTCTTGGAGAAGTCTCTG
AAGAAAGAGTCCAGAAACAAAGAGACTGACAAAGTGAAGCTGACATGGAGAGATCGGTTCCCAGCCTACCTCACTAACTTGGTCTCCATC
ATCTTCATGATTGCAGTGACGTTTGCCATCGTCCTCGGCGTCATCATCTACAGAATCTCCATGGCCGCCGCCTTGGCCATGAACTCCTCC
CCCTCCGTGCGGTCCAACATCCGGGTCACAGTCACAGCCACCGCAGTCATCATCAACCTAGTGGTCATCATCCTCCTGGACGAGGTGTAT
GGCTGCATAGCCCGATGGCTCACCAAGATCGAGGTCCCAAAGACGGAGAAAAGCTTTGAGGAGAGGCTGATCTTCAAGGCTTTCCTGCTG
AAGTTTGTGAATTCCTACACCCCCATCTTTTACGTGGCGTTCTTCAAAGGCCGGTTTGTTGGACGCCCGGGCGACTACGTGTACATTTTC
CGTTCCTTCCGAATGGAAGAGTGTGCGCCAGGGGGCTGCCTGATGGAGCTATGCATCCAGCTCAGCATCATCATGCTGGGGAAACAGCTG
ATCCAGAACAACCTGTTCGAGATCGGCATCCCGAAGATGAAGAAGCTCATCCGCTACCTGAAGCTGAAGCAGCAGAGCCCCCCTGACCAC
GAGGAGTGTGTGAAGAGGAAACAGCGGTACGAGGTGGATTACAACCTGGAGCCCTTCGCGGGCCTCACCCCAGAGTACATGGAAATGATC
ATCCAGTTTGGCTTCGTCACCCTGTTTGTCGCCTCCTTCCCCCTGGCCCCACTGTTTGCGCTGCTGAACAACATCATCGAGATCCGCCTG
GACGCCAAAAAGTTTGTCACTGAGCTCCGAAGGCCGGTAGCTGTCAGAGCCAAAGACATCGGGAACATCATCGGCTCTGGAATCTTTGTC
TCGCCAAAGGGAGTGCTGGAGAATGCTGGTTCTGTGGGCCTTGCTCTCATCGTCTGGATTGTGACGGGCTTCATCACAGTTGTGGGAGCC
CTCTGCTATGCTGAACTCGGGGTCACCATCCCCAAATCTGGAGGTGACTACTCCTATGTCAAGGACATCTTCGGAGGACTGGCTGGGTTC
CTGAGGCTGTGGATTGCTGTGCTGGTGATCTACCCCACCAACCAGGCTGTCATCGCCCTCACCTTCTCCAACTACGTGCTGCAGCCGCTC
TTCCCCACCTGCTTCCCCCCAGAGTCTGGCCTTCGGCTCCTGGCTGCCATCTGCTTATTGCTCCTCACATGGGTCAACTGTTCCAGTGTG
CGGTGGGCCACCCGGGTTCAAGACATCTTCACAGCTGGGAAGCTCCTGGCCTTGGCCCTGATTATCATCATGGGGATTGTACAGATATGC
AAAGGAGAGTACTTCTGGCTGGAGCCAAAGAATGCATTTGAGAATTTCCAGGAACCTGACATCGGCCTCGTCGCACTGGCTTTCCTTCAG
GGCTCCTTTGCCTATGGAGGCTGGAACTTTCTGAATTACGTGACTGAGGAGCTTGTTGATCCCTACAAAGCTGCTAACCCTGGTGAGCCA
GAAGATGTGTGTGGTCGTGTACCCCGAGGTGGAGCGGGGCTCAGGGACAGAGGAGGCTAATGAGGACATGGAGGAGCAGCAGCAGCCCAT
GTACCAACCCACTCCCACGAAGGACAAGGACGTGGCGGGGCAGCCCCAGCCCTGAGGACCACCATTCCCTGGCTACTCTCTCCTTCCTCC
CCCTTTTATCCTACCTCCCTGCCTTGGTCCTGCCAACACATGCGAGTACACACACACCCCTCTCTCTGCTTTTGTCAGGCAGTGGTAGGA
CTTTGGTGTGGGTGGTGAGAAATTGTAAACAAAAACTGACATTCATACCCAAAGAACCAGCCTCTCACCCCAGGGTCCATGTCCCAGGCC
CCACTCCAGTGCTGCCCACACTCCCAGCTGCTGGAGGAGAGGGGAGATGCCAAGGTGCCCTGCAGGACCTCCCTCCGGGCCACACCCTCA
GCTGCCTCTTCAGGAACCGGAGCTCATTACTGCCTTCCCTCCCAGGGAGGCCCCTTCAGAGAGGAGAGGCCACAGGAGCTGCATTGTGGG
GGGACAGGCTCAAGCAATTCTGTCCCCATCAAGGGGTCAGCTGGAGAGACCCAAGACCCTATCTGTTCACCAGGGACCCAAAATCCAAGG
GGATGCTTCCCTCTGCCCTCTTTCCTGCCCCTCCCCATCATACCTGCACCCACCCCAGCCAGGGCTCCCTGTCCAGAATTCGGTTCTCCT
CAGGACGCCAACTCCCAGAGCTAAGGACCAAGGAGAAGAACAGCCTCTCCACCCCCAAGCCAGGCGGTTGAGGAACATATTGAGAAAGGT
TCAGATTGCAGAAACCCAGCCCTGCCCCTGCCTCCTGCATCCAGCCCCCAACATGGTGCCAAAGCTTCCAGAAGCCAAAAAGCTTCTGAT
TTTTAAGGTAGTGGGCATCTCTCTCCTAATGACGAAGCTGCTCAGCAACTCCACCTGCCCGCCGCAGGAAGGAGCAGTCCCCTGCTATCC
CTGCAGCCACTCCCAGCACACCCGCACACAGCCAGCACCACCGCCCCCACCGTGCACTTCTCCTCTCTGGGCCTTGGCTTGGGACCAGGT
ACGAAGGATCCCCAAGCCCTTCAGGCCTGAGATCAGAGCCAGATCAGCCTTAAGTCACCTCCCATCCAAGAACTTGGCCTAAAAATACTC
CCCTATTTCTAACCCTCAGGACGGATCTGATATTAAATGCCTTCCCTGGGAGGAAGGGTGCTTTCCCCCTCCCTAGAGGTGCCCATTCCA
TACCCTGGGAGACTGAGGAGAGCATTGGCTGAAGCCCAGTTCCTTTCCCATCCATCCCCAACTCCAATAATCCCCCACTCCTCGCAGGTC
TCAGTGTCATGCTGTCTTGGGGCAGGGTGAAAGGGTAGTGGCAGCAGGGCGCCCACTCTGGAGATCCTCAAAAAAGGCCCTCCTCTGTGG
CTGGCAGCCTCTGACCTTTCCCTGGGCTTCAAAGGAAGGCTATGGAGTTTGCTGTGGGCCCTGCAACCTTCCCAGCCACTCCTGCTGCAC
TAAGGACTTAGGATCCTTTTATCACAAATCGGGATTCTCTCCCCCACCCCGAATTCTGTCTGCTTAAACTGGAATACACAGGAGCCCTTC
CTGGCCTGGATGGTGTCTCCCAGCTTCCCCGCCCAGCTTGCCCACCCCATAGTTGGTGAGATGCCAAGTTTGGTCTGAGTTGTGACCCCT
TCAGAGTAGATGCCCGGCAGGCTGGGGTTGGCCCCTGGAGGGTCAGGGGACCATCTTCTTATTCCCTCTTTTCTCATTCCTCCAACTTCC
TCCCCTCCTTCAATTATTTTTTTGTAAAGTTGATGCCTTACTTTTTGGATAAATATTTTTGAAGCTGGTATTTCTATTTCTTTTGGATTT
TTTTTAATGTAAGGTTGTTTTGGGGGATGGAGTTAGAACCTTAATGATAATTTCTTTCGTTTGGTGTAGGTTTTAGAGATTTGTTTTGTG

>4864_4864_6_ANO1-SLC7A8_ANO1_chr11_70017145_ENST00000530676_SLC7A8_chr14_23635749_ENST00000469263_length(amino acids)=956AA_BP=717
MLNSLSVDPDAECKYGLYFRDGRRKVDYILVYHHKRPSGNRTLVRRVQHSDTPSGARSVKQDHPLPGKGASLDAGSGEPPMDYHEDDKRF
RREEYEGNLLEAGLELERDEDTKIHGVGFVKIHAPWNVLCREAEFLKLKMPTKKMYHINETRGLLKKINSVLQKITDPIQPKVAEHRPQT
MKRLSYPFSREKQHLFDLSDKDSFFDSKTRSTIVYEILKRTTCTKAKYSMGITSLLANGVYAAAYPLHDGDYNGENVEFNDRKLLYEEWA
RYGVFYKYQPIDLVRKYFGEKIGLYFAWLGVYTQMLIPASIVGIIVFLYGCATMDENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACA
TARASHLFDNPATVFFSVFMALWAATFMEHWKRKQMRLNYRWDLTGFEEEEDHPRAEYEARVLEKSLKKESRNKETDKVKLTWRDRFPAY
LTNLVSIIFMIAVTFAIVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERL
IFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLK
QQSPPDHEECVKRKQRYEVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAVRAKDIGNI
IGSGIFVSPKGVLENAGSVGLALIVWIVTGFITVVGALCYAELGVTIPKSGGDYSYVKDIFGGLAGFLRLWIAVLVIYPTNQAVIALTFS
NYVLQPLFPTCFPPESGLRLLAAICLLLLTWVNCSSVRWATRVQDIFTAGKLLALALIIIMGIVQICKGEYFWLEPKNAFENFQEPDIGL

--------------------------------------------------------------
>4864_4864_7_ANO1-SLC7A8_ANO1_chr11_70017145_ENST00000531349_SLC7A8_chr14_23635749_ENST00000316902_length(transcript)=5032nt_BP=1693nt
TGGGTCAACCCTCCCTGAATAAATGCCATTGTCTTTCCTTGGAAGATAGCACCAAGGAGGTCTTCATGCGTAACGTGTGACCAGGTCCTC
TCCAGCCACAGCAGACTGTTTCTGCTCGTGGAAGGTGCCTTAAGTAACTGCTCACCCCCCTTCTTGTCTCTGCAATAGGTCTATGAGATC
TTGAAGAGAACGACGTGTACAAAGGCCAAGTACAGCATGGGCATCACGAGCCTGCTGGCCAATGGTGTGTACGCGGCTGCATACCCACTG
CACGATGGAGACTACAACGGTGAAAACGTCGAGTTCAACGACAGAAAACTCCTGTACGAAGAGTGGGCACGCTATGGAGTTTTCTATAAG
TACCAGCCCATCGACCTGGTCAGGAAGTATTTTGGGGAGAAGATCGGCCTGTACTTCGCCTGGCTGGGCGTGTACACCCAGATGCTCATC
CCTGCCTCCATCGTGGGAATCATTGTCTTCCTGTACGGATGCGCCACCATGGATGAAAACATCCCCAGCATGGAGATGTGTGACCAGAGA
CACAATATCACCATGTGCCCGCTTTGCGACAAGACCTGCAGCTACTGGAAGATGAGCTCAGCCTGCGCCACGGCCCGCGCCAGCCACCTC
TTCGACAACCCCGCCACGGTCTTCTTCTCTGTCTTCATGGCCCTCTGGGCTGCCACCTTCATGGAGCACTGGAAGCGGAAACAGATGCGA
CTCAACTACCGCTGGGACCTCACGGGCTTTGAAGAGGAAGAGGAGGCTGTCAAGGATCATCCTAGAGCTGAATACGAAGCCAGAGTCTTG
GAGAAGTCTCTGAAGAAAGAGTCCAGAAACAAAGAGACTGACAAAGTGAAGCTGACATGGAGAGATCGGTTCCCAGCCTACCTCACTAAC
TTGGTCTCCATCATCTTCATGATTGCAGTGACGTTTGCCATCGTCCTCGGCGTCATCATCTACAGAATCTCCATGGCCGCCGCCTTGGCC
ATGAACTCCTCCCCCTCCGTGCGGTCCAACATCCGGGTCACAGTCACAGCCACCGCAGTCATCATCAACCTAGTGGTCATCATCCTCCTG
GACGAGGTGTATGGCTGCATAGCCCGATGGCTCACCAAGATCGAGGTCCCAAAGACGGAGAAAAGCTTTGAGGAGAGGCTGATCTTCAAG
GCTTTCCTGCTGAAGTTTGTGAATTCCTACACCCCCATCTTTTACGTGGCGTTCTTCAAAGGCCGGTTTGTTGGACGCCCGGGCGACTAC
GTGTACATTTTCCGTTCCTTCCGAATGGAAGAGTGTGCGCCAGGGGGCTGCCTGATGGAGCTATGCATCCAGCTCAGCATCATCATGCTG
GGGAAACAGCTGATCCAGAACAACCTGTTCGAGATCGGCATCCCGAAGATGAAGAAGCTCATCCGCTACCTGAAGCTGAAGCAGCAGAGC
CCCCCTGACCACGAGGAGTGTGTGAAGAGGAAACAGCGGTACGAGGTGGATTACAACCTGGAGCCCTTCGCGGGCCTCACCCCAGAGTAC
ATGGAAATGATCATCCAGTTTGGCTTCGTCACCCTGTTTGTCGCCTCCTTCCCCCTGGCCCCACTGTTTGCGCTGCTGAACAACATCATC
GAGATCCGCCTGGACGCCAAAAAGTTTGTCACTGAGCTCCGAAGGCCGGTAGCTGTCAGAGCCAAAGACATCGGGAACATCATCGGCTCT
GGAATCTTTGTCTCGCCAAAGGGAGTGCTGGAGAATGCTGGTTCTGTGGGCCTTGCTCTCATCGTCTGGATTGTGACGGGCTTCATCACA
GTTGTGGGAGCCCTCTGCTATGCTGAACTCGGGGTCACCATCCCCAAATCTGGAGGTGACTACTCCTATGTCAAGGACATCTTCGGAGGA
CTGGCTGGGTTCCTGAGGCTGTGGATTGCTGTGCTGGTGATCTACCCCACCAACCAGGCTGTCATCGCCCTCACCTTCTCCAACTACGTG
CTGCAGCCGCTCTTCCCCACCTGCTTCCCCCCAGAGTCTGGCCTTCGGCTCCTGGCTGCCATCTGCTTATTGCTCCTCACATGGGTCAAC
TGTTCCAGTGTGCGGTGGGCCACCCGGGTTCAAGACATCTTCACAGCTGGGAAGCTCCTGGCCTTGGCCCTGATTATCATCATGGGGATT
GTACAGATATGCAAAGGAGAGTACTTCTGGCTGGAGCCAAAGAATGCATTTGAGAATTTCCAGGAACCTGACATCGGCCTCGTCGCACTG
GCTTTCCTTCAGGGCTCCTTTGCCTATGGAGGCTGGAACTTTCTGAATTACGTGACTGAGGAGCTTGTTGATCCCTACAAGAACCTTCCC
AGAGCCATCTTCATCTCCATCCCACTGGTCACATTTGTGTATGTCTTTGCCAATGTCGCTTATGTCACTGCAATGTCCCCCCAGGAGCTG
CTGGCATCCAACGCCGTCGCTGTGACTTTTGGAGAGAAGCTCCTAGGAGTCATGGCCTGGATCATGCCCATTTCTGTTGCCCTGTCCACA
TTTGGAGGAGTTAATGGGTCTCTCTTCACCTCCTCTCGGCTGTTCTTCGCTGGAGCCCGAGAGGGCCACCTTCCCAGTGTGTTGGCCATG
ATCCACGTGAAGCGCTGCACCCCAATCCCAGCCCTGCTCTTCACATGCATCTCCACCCTGCTGATGCTGGTCACCAGCGACATGTACACA
CTCATCAACTATGTGGGCTTCATCAACTACCTCTTCTATGGGGTCACGGTTGCTGGACAGATAGTCCTTCGCTGGAAGAAGCCTGATATC
CCCCGCCCCATCAAGATCAACCTGCTGTTCCCCATCATCTACTTGCTGTTCTGGGCCTTCCTGCTGGTCTTCAGCCTGTGGTCAGAGCCG
GTGGTGTGTGGCATTGGCCTGGCCATCATGCTGACAGGAGTGCCTGTCTATTTCCTGGGTGTTTACTGGCAACACAAGCCCAAGTGTTTC
AGTGACTTCATTGAGCTGCTAACCCTGGTGAGCCAGAAGATGTGTGTGGTCGTGTACCCCGAGGTGGAGCGGGGCTCAGGGACAGAGGAG
GCTAATGAGGACATGGAGGAGCAGCAGCAGCCCATGTACCAACCCACTCCCACGAAGGACAAGGACGTGGCGGGGCAGCCCCAGCCCTGA
GGACCACCATTCCCTGGCTACTCTCTCCTTCCTCCCCCTTTTATCCTACCTCCCTGCCTTGGTCCTGCCAACACATGCGAGTACACACAC
ACCCCTCTCTCTGCTTTTGTCAGGCAGTGGTAGGACTTTGGTGTGGGTGGTGAGAAATTGTAAACAAAAACTGACATTCATACCCAAAGA
ACCAGCCTCTCACCCCAGGGTCCATGTCCCAGGCCCCACTCCAGTGCTGCCCACACTCCCAGCTGCTGGAGGAGAGGGGAGATGCCAAGG
TGCCCTGCAGGACCTCCCTCCGGGCCACACCCTCAGCTGCCTCTTCAGGAACCGGAGCTCATTACTGCCTTCCCTCCCAGGGAGGCCCCT
TCAGAGAGGAGAGGCCACAGGAGCTGCATTGTGGGGGGACAGGCTCAAGCAATTCTGTCCCCATCAAGGGGTCAGCTGGAGAGACCCAAG
ACCCTATCTGTTCACCAGGGACCCAAAATCCAAGGGGATGCTTCCCTCTGCCCTCTTTCCTGCCCCTCCCCATCATACCTGCACCCACCC
CAGCCAGGGCTCCCTGTCCAGAATTCGGTTCTCCTCAGGACGCCAACTCCCAGAGCTAAGGACCAAGGAGAAGAACAGCCTCTCCACCCC
CAAGCCAGGCGGTTGAGGAACATATTGAGAAAGGTTCAGATTGCAGAAACCCAGCCCTGCCCCTGCCTCCTGCATCCAGCCCCCAACATG
GTGCCAAAGCTTCCAGAAGCCAAAAAGCTTCTGATTTTTAAGGTAGTGGGCATCTCTCTCCTAATGACGAAGCTGCTCAGCAACTCCACC
TGCCCGCCGCAGGAAGGAGCAGTCCCCTGCTATCCCTGCAGCCACTCCCAGCACACCCGCACACAGCCAGCACCACCGCCCCCACCGTGC
ACTTCTCCTCTCTGGGCCTTGGCTTGGGACCAGGTACGAAGGATCCCCAAGCCCTTCAGGCCTGAGATCAGAGCCAGATCAGCCTTAAGT
CACCTCCCATCCAAGAACTTGGCCTAAAAATACTCCCCTATTTCTAACCCTCAGGACGGATCTGATATTAAATGCCTTCCCTGGGAGGAA
GGGTGCTTTCCCCCTCCCTAGAGGTGCCCATTCCATACCCTGGGAGACTGAGGAGAGCATTGGCTGAAGCCCAGTTCCTTTCCCATCCAT
CCCCAACTCCAATAATCCCCCACTCCTCGCAGGTCTCAGTGTCATGCTGTCTTGGGGCAGGGTGAAAGGGTAGTGGCAGCAGGGCGCCCA
CTCTGGAGATCCTCAAAAAAGGCCCTCCTCTGTGGCTGGCAGCCTCTGACCTTTCCCTGGGCTTCAAAGGAAGGCTATGGAGTTTGCTGT
GGGCCCTGCAACCTTCCCAGCCACTCCTGCTGCACTAAGGACTTAGGATCCTTTTATCACAAATCGGGATTCTCTCCCCCACCCCGAATT
CTGTCTGCTTAAACTGGAATACACAGGAGCCCTTCCTGGCCTGGATGGTGTCTCCCAGCTTCCCCGCCCAGCTTGCCCACCCCATAGTTG
GTGAGATGCCAAGTTTGGTCTGAGTTGTGACCCCTTCAGAGTAGATGCCCGGCAGGCTGGGGTTGGCCCCTGGAGGGTCAGGGGACCATC
TTCTTATTCCCTCTTTTCTCATTCCTCCAACTTCCTCCCCTCCTTCAATTATTTTTTTGTAAAGTTGATGCCTTACTTTTTGGATAAATA
TTTTTGAAGCTGGTATTTCTATTTCTTTTGGATTTTTTTTAATGTAAGGTTGTTTTGGGGGATGGAGTTAGAACCTTAATGATAATTTCT

>4864_4864_7_ANO1-SLC7A8_ANO1_chr11_70017145_ENST00000531349_SLC7A8_chr14_23635749_ENST00000316902_length(amino acids)=989AA_BP=504
MKRTTCTKAKYSMGITSLLANGVYAAAYPLHDGDYNGENVEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEKIGLYFAWLGVYTQMLI
PASIVGIIVFLYGCATMDENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMALWAATFMEHWKRKQMR
LNYRWDLTGFEEEEEAVKDHPRAEYEARVLEKSLKKESRNKETDKVKLTWRDRFPAYLTNLVSIIFMIAVTFAIVLGVIIYRISMAAALA
MNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDY
VYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECVKRKQRYEVDYNLEPFAGLTPEY
MEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAVRAKDIGNIIGSGIFVSPKGVLENAGSVGLALIVWIVTGFIT
VVGALCYAELGVTIPKSGGDYSYVKDIFGGLAGFLRLWIAVLVIYPTNQAVIALTFSNYVLQPLFPTCFPPESGLRLLAAICLLLLTWVN
CSSVRWATRVQDIFTAGKLLALALIIIMGIVQICKGEYFWLEPKNAFENFQEPDIGLVALAFLQGSFAYGGWNFLNYVTEELVDPYKNLP
RAIFISIPLVTFVYVFANVAYVTAMSPQELLASNAVAVTFGEKLLGVMAWIMPISVALSTFGGVNGSLFTSSRLFFAGAREGHLPSVLAM
IHVKRCTPIPALLFTCISTLLMLVTSDMYTLINYVGFINYLFYGVTVAGQIVLRWKKPDIPRPIKINLLFPIIYLLFWAFLLVFSLWSEP

--------------------------------------------------------------
>4864_4864_8_ANO1-SLC7A8_ANO1_chr11_70017145_ENST00000531349_SLC7A8_chr14_23635749_ENST00000469263_length(transcript)=4372nt_BP=1693nt
TGGGTCAACCCTCCCTGAATAAATGCCATTGTCTTTCCTTGGAAGATAGCACCAAGGAGGTCTTCATGCGTAACGTGTGACCAGGTCCTC
TCCAGCCACAGCAGACTGTTTCTGCTCGTGGAAGGTGCCTTAAGTAACTGCTCACCCCCCTTCTTGTCTCTGCAATAGGTCTATGAGATC
TTGAAGAGAACGACGTGTACAAAGGCCAAGTACAGCATGGGCATCACGAGCCTGCTGGCCAATGGTGTGTACGCGGCTGCATACCCACTG
CACGATGGAGACTACAACGGTGAAAACGTCGAGTTCAACGACAGAAAACTCCTGTACGAAGAGTGGGCACGCTATGGAGTTTTCTATAAG
TACCAGCCCATCGACCTGGTCAGGAAGTATTTTGGGGAGAAGATCGGCCTGTACTTCGCCTGGCTGGGCGTGTACACCCAGATGCTCATC
CCTGCCTCCATCGTGGGAATCATTGTCTTCCTGTACGGATGCGCCACCATGGATGAAAACATCCCCAGCATGGAGATGTGTGACCAGAGA
CACAATATCACCATGTGCCCGCTTTGCGACAAGACCTGCAGCTACTGGAAGATGAGCTCAGCCTGCGCCACGGCCCGCGCCAGCCACCTC
TTCGACAACCCCGCCACGGTCTTCTTCTCTGTCTTCATGGCCCTCTGGGCTGCCACCTTCATGGAGCACTGGAAGCGGAAACAGATGCGA
CTCAACTACCGCTGGGACCTCACGGGCTTTGAAGAGGAAGAGGAGGCTGTCAAGGATCATCCTAGAGCTGAATACGAAGCCAGAGTCTTG
GAGAAGTCTCTGAAGAAAGAGTCCAGAAACAAAGAGACTGACAAAGTGAAGCTGACATGGAGAGATCGGTTCCCAGCCTACCTCACTAAC
TTGGTCTCCATCATCTTCATGATTGCAGTGACGTTTGCCATCGTCCTCGGCGTCATCATCTACAGAATCTCCATGGCCGCCGCCTTGGCC
ATGAACTCCTCCCCCTCCGTGCGGTCCAACATCCGGGTCACAGTCACAGCCACCGCAGTCATCATCAACCTAGTGGTCATCATCCTCCTG
GACGAGGTGTATGGCTGCATAGCCCGATGGCTCACCAAGATCGAGGTCCCAAAGACGGAGAAAAGCTTTGAGGAGAGGCTGATCTTCAAG
GCTTTCCTGCTGAAGTTTGTGAATTCCTACACCCCCATCTTTTACGTGGCGTTCTTCAAAGGCCGGTTTGTTGGACGCCCGGGCGACTAC
GTGTACATTTTCCGTTCCTTCCGAATGGAAGAGTGTGCGCCAGGGGGCTGCCTGATGGAGCTATGCATCCAGCTCAGCATCATCATGCTG
GGGAAACAGCTGATCCAGAACAACCTGTTCGAGATCGGCATCCCGAAGATGAAGAAGCTCATCCGCTACCTGAAGCTGAAGCAGCAGAGC
CCCCCTGACCACGAGGAGTGTGTGAAGAGGAAACAGCGGTACGAGGTGGATTACAACCTGGAGCCCTTCGCGGGCCTCACCCCAGAGTAC
ATGGAAATGATCATCCAGTTTGGCTTCGTCACCCTGTTTGTCGCCTCCTTCCCCCTGGCCCCACTGTTTGCGCTGCTGAACAACATCATC
GAGATCCGCCTGGACGCCAAAAAGTTTGTCACTGAGCTCCGAAGGCCGGTAGCTGTCAGAGCCAAAGACATCGGGAACATCATCGGCTCT
GGAATCTTTGTCTCGCCAAAGGGAGTGCTGGAGAATGCTGGTTCTGTGGGCCTTGCTCTCATCGTCTGGATTGTGACGGGCTTCATCACA
GTTGTGGGAGCCCTCTGCTATGCTGAACTCGGGGTCACCATCCCCAAATCTGGAGGTGACTACTCCTATGTCAAGGACATCTTCGGAGGA
CTGGCTGGGTTCCTGAGGCTGTGGATTGCTGTGCTGGTGATCTACCCCACCAACCAGGCTGTCATCGCCCTCACCTTCTCCAACTACGTG
CTGCAGCCGCTCTTCCCCACCTGCTTCCCCCCAGAGTCTGGCCTTCGGCTCCTGGCTGCCATCTGCTTATTGCTCCTCACATGGGTCAAC
TGTTCCAGTGTGCGGTGGGCCACCCGGGTTCAAGACATCTTCACAGCTGGGAAGCTCCTGGCCTTGGCCCTGATTATCATCATGGGGATT
GTACAGATATGCAAAGGAGAGTACTTCTGGCTGGAGCCAAAGAATGCATTTGAGAATTTCCAGGAACCTGACATCGGCCTCGTCGCACTG
GCTTTCCTTCAGGGCTCCTTTGCCTATGGAGGCTGGAACTTTCTGAATTACGTGACTGAGGAGCTTGTTGATCCCTACAAAGCTGCTAAC
CCTGGTGAGCCAGAAGATGTGTGTGGTCGTGTACCCCGAGGTGGAGCGGGGCTCAGGGACAGAGGAGGCTAATGAGGACATGGAGGAGCA
GCAGCAGCCCATGTACCAACCCACTCCCACGAAGGACAAGGACGTGGCGGGGCAGCCCCAGCCCTGAGGACCACCATTCCCTGGCTACTC
TCTCCTTCCTCCCCCTTTTATCCTACCTCCCTGCCTTGGTCCTGCCAACACATGCGAGTACACACACACCCCTCTCTCTGCTTTTGTCAG
GCAGTGGTAGGACTTTGGTGTGGGTGGTGAGAAATTGTAAACAAAAACTGACATTCATACCCAAAGAACCAGCCTCTCACCCCAGGGTCC
ATGTCCCAGGCCCCACTCCAGTGCTGCCCACACTCCCAGCTGCTGGAGGAGAGGGGAGATGCCAAGGTGCCCTGCAGGACCTCCCTCCGG
GCCACACCCTCAGCTGCCTCTTCAGGAACCGGAGCTCATTACTGCCTTCCCTCCCAGGGAGGCCCCTTCAGAGAGGAGAGGCCACAGGAG
CTGCATTGTGGGGGGACAGGCTCAAGCAATTCTGTCCCCATCAAGGGGTCAGCTGGAGAGACCCAAGACCCTATCTGTTCACCAGGGACC
CAAAATCCAAGGGGATGCTTCCCTCTGCCCTCTTTCCTGCCCCTCCCCATCATACCTGCACCCACCCCAGCCAGGGCTCCCTGTCCAGAA
TTCGGTTCTCCTCAGGACGCCAACTCCCAGAGCTAAGGACCAAGGAGAAGAACAGCCTCTCCACCCCCAAGCCAGGCGGTTGAGGAACAT
ATTGAGAAAGGTTCAGATTGCAGAAACCCAGCCCTGCCCCTGCCTCCTGCATCCAGCCCCCAACATGGTGCCAAAGCTTCCAGAAGCCAA
AAAGCTTCTGATTTTTAAGGTAGTGGGCATCTCTCTCCTAATGACGAAGCTGCTCAGCAACTCCACCTGCCCGCCGCAGGAAGGAGCAGT
CCCCTGCTATCCCTGCAGCCACTCCCAGCACACCCGCACACAGCCAGCACCACCGCCCCCACCGTGCACTTCTCCTCTCTGGGCCTTGGC
TTGGGACCAGGTACGAAGGATCCCCAAGCCCTTCAGGCCTGAGATCAGAGCCAGATCAGCCTTAAGTCACCTCCCATCCAAGAACTTGGC
CTAAAAATACTCCCCTATTTCTAACCCTCAGGACGGATCTGATATTAAATGCCTTCCCTGGGAGGAAGGGTGCTTTCCCCCTCCCTAGAG
GTGCCCATTCCATACCCTGGGAGACTGAGGAGAGCATTGGCTGAAGCCCAGTTCCTTTCCCATCCATCCCCAACTCCAATAATCCCCCAC
TCCTCGCAGGTCTCAGTGTCATGCTGTCTTGGGGCAGGGTGAAAGGGTAGTGGCAGCAGGGCGCCCACTCTGGAGATCCTCAAAAAAGGC
CCTCCTCTGTGGCTGGCAGCCTCTGACCTTTCCCTGGGCTTCAAAGGAAGGCTATGGAGTTTGCTGTGGGCCCTGCAACCTTCCCAGCCA
CTCCTGCTGCACTAAGGACTTAGGATCCTTTTATCACAAATCGGGATTCTCTCCCCCACCCCGAATTCTGTCTGCTTAAACTGGAATACA
CAGGAGCCCTTCCTGGCCTGGATGGTGTCTCCCAGCTTCCCCGCCCAGCTTGCCCACCCCATAGTTGGTGAGATGCCAAGTTTGGTCTGA
GTTGTGACCCCTTCAGAGTAGATGCCCGGCAGGCTGGGGTTGGCCCCTGGAGGGTCAGGGGACCATCTTCTTATTCCCTCTTTTCTCATT
CCTCCAACTTCCTCCCCTCCTTCAATTATTTTTTTGTAAAGTTGATGCCTTACTTTTTGGATAAATATTTTTGAAGCTGGTATTTCTATT
TCTTTTGGATTTTTTTTAATGTAAGGTTGTTTTGGGGGATGGAGTTAGAACCTTAATGATAATTTCTTTCGTTTGGTGTAGGTTTTAGAG

>4864_4864_8_ANO1-SLC7A8_ANO1_chr11_70017145_ENST00000531349_SLC7A8_chr14_23635749_ENST00000469263_length(amino acids)=743AA_BP=504
MKRTTCTKAKYSMGITSLLANGVYAAAYPLHDGDYNGENVEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEKIGLYFAWLGVYTQMLI
PASIVGIIVFLYGCATMDENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMALWAATFMEHWKRKQMR
LNYRWDLTGFEEEEEAVKDHPRAEYEARVLEKSLKKESRNKETDKVKLTWRDRFPAYLTNLVSIIFMIAVTFAIVLGVIIYRISMAAALA
MNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDY
VYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECVKRKQRYEVDYNLEPFAGLTPEY
MEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAVRAKDIGNIIGSGIFVSPKGVLENAGSVGLALIVWIVTGFIT
VVGALCYAELGVTIPKSGGDYSYVKDIFGGLAGFLRLWIAVLVIYPTNQAVIALTFSNYVLQPLFPTCFPPESGLRLLAAICLLLLTWVN
CSSVRWATRVQDIFTAGKLLALALIIIMGIVQICKGEYFWLEPKNAFENFQEPDIGLVALAFLQGSFAYGGWNFLNYVTEELVDPYKAAN

--------------------------------------------------------------
>4864_4864_9_ANO1-SLC7A8_ANO1_chr11_70017145_ENST00000538023_SLC7A8_chr14_23635749_ENST00000316902_length(transcript)=5738nt_BP=2399nt
GGATGGGGAGGGCGCGCCGCCCGGCGGTCCCAGCGCACAGGCGGCCACGATGAGGGTCAACGAGAAGTACTCGACGCTCCCGGCCGAGGA
CCGCAGCGTCCACATCATCAACATCTGCGCCATCGAGGACATCGGCTACCTGCCGTCCGAGGGCACGCTGCTGAACTCCTTATCTGTGGA
CCCTGATGCCGAGTGCAAGTATGGCCTGTACTTCAGGGACGGCCGGCGCAAGGTGGACTACATCCTGGTGTACCATCACAAGAGGCCCTC
GGGCAACCGGACCCTGGTCAGGAGGGTGCAGCACAGCGACACCCCCTCTGGGGCTCGCAGCGTCAAGCAGGACCACCCCCTGCCGGGCAA
GGGGGCGTCGCTGGATGCAGGCTCGGGGGAGCCCCCGATGGACTACCACGAGGATGACAAGCGCTTCCGCAGGGAGGAGTACGAGGGCAA
CCTCCTGGAGGCGGGCCTGGAGCTGGAGCGGGACGAGGACACTAAAATCCACGGAGTCGGGTTTGTGAAAATCCATGCCCCCTGGAACGT
GCTGTGCAGAGAGGCCGAGTTTCTGAAACTGAAGATGCCGACGAAGAAGATGTACCACATTAATGAGACCCGTGGCCTCCTGAAAAAAAT
CAACTCTGTGCTCCAGAAAATCACAGATCCCATCCAGCCCAAAGTGGCTGAGCACAGGCCCCAGACCATGAAGAGACTCTCCTATCCCTT
CTCCCGGGAGAAGCAGCATCTATTTGACTTGTCTGATAAGGATTCCTTTTTCGACAGCAAAACCCGGAGCACGATTGTCTATGAGATCTT
GAAGAGAACGACGTGTACAAAGGCCAAGTACAGCATGGGCATCACGAGCCTGCTGGCCAATGGTGTGTACGCGGCTGCATACCCACTGCA
CGATGGAGACTACAACGGTGAAAACGTCGAGTTCAACGACAGAAAACTCCTGTACGAAGAGTGGGCACGCTATGGAGTTTTCTATAAGTA
CCAGCCCATCGACCTGGTCAGGAAGTATTTTGGGGAGAAGATCGGCCTGTACTTCGCCTGGCTGGGCGTGTACACCCAGATGCTCATCCC
TGCCTCCATCGTGGGAATCATTGTCTTCCTGTACGGATGCGCCACCATGGATGAAAACATCCCCAGCATGGAGATGTGTGACCAGAGACA
CAATATCACCATGTGCCCGCTTTGCGACAAGACCTGCAGCTACTGGAAGATGAGCTCAGCCTGCGCCACGGCCCGCGCCAGCCACCTCTT
CGACAACCCCGCCACGGTCTTCTTCTCTGTCTTCATGGCCCTCTGGGCTGCCACCTTCATGGAGCACTGGAAGCGGAAACAGATGCGACT
CAACTACCGCTGGGACCTCACGGGCTTTGAAGAGGAAGAGAAAGCACTTCTGGATCATCCTAGAGCTGAATACGAAGCCAGAGTCTTGGA
GAAGTCTCTGAAGAAAGAGTCCAGAAACAAAGAGAAGCGCCGGCATATTCCAGAGGAGTCAACAAACAAATGGAAGCAGAGGGTTAAGAC
AGCCATGGCGGGGGTGAAATTGACTGACAAAGTGAAGCTGACATGGAGAGATCGGTTCCCAGCCTACCTCACTAACTTGGTCTCCATCAT
CTTCATGATTGCAGTGACGTTTGCCATCGTCCTCGGCGTCATCATCTACAGAATCTCCATGGCCGCCGCCTTGGCCATGAACTCCTCCCC
CTCCGTGCGGTCCAACATCCGGGTCACAGTCACAGCCACCGCAGTCATCATCAACCTAGTGGTCATCATCCTCCTGGACGAGGTGTATGG
CTGCATAGCCCGATGGCTCACCAAGATCGAGGTCCCAAAGACGGAGAAAAGCTTTGAGGAGAGGCTGATCTTCAAGGCTTTCCTGCTGAA
GTTTGTGAATTCCTACACCCCCATCTTTTACGTGGCGTTCTTCAAAGGCCGGTTTGTTGGACGCCCGGGCGACTACGTGTACATTTTCCG
TTCCTTCCGAATGGAAGAGTGTGCGCCAGGGGGCTGCCTGATGGAGCTATGCATCCAGCTCAGCATCATCATGCTGGGGAAACAGCTGAT
CCAGAACAACCTGTTCGAGATCGGCATCCCGAAGATGAAGAAGCTCATCCGCTACCTGAAGCTGAAGCAGCAGAGCCCCCCTGACCACGA
GGAGTGTGTGAAGAGGAAACAGCGGTACGAGGTGGATTACAACCTGGAGCCCTTCGCGGGCCTCACCCCAGAGTACATGGAAATGATCAT
CCAGTTTGGCTTCGTCACCCTGTTTGTCGCCTCCTTCCCCCTGGCCCCACTGTTTGCGCTGCTGAACAACATCATCGAGATCCGCCTGGA
CGCCAAAAAGTTTGTCACTGAGCTCCGAAGGCCGGTAGCTGTCAGAGCCAAAGACATCGGGAACATCATCGGCTCTGGAATCTTTGTCTC
GCCAAAGGGAGTGCTGGAGAATGCTGGTTCTGTGGGCCTTGCTCTCATCGTCTGGATTGTGACGGGCTTCATCACAGTTGTGGGAGCCCT
CTGCTATGCTGAACTCGGGGTCACCATCCCCAAATCTGGAGGTGACTACTCCTATGTCAAGGACATCTTCGGAGGACTGGCTGGGTTCCT
GAGGCTGTGGATTGCTGTGCTGGTGATCTACCCCACCAACCAGGCTGTCATCGCCCTCACCTTCTCCAACTACGTGCTGCAGCCGCTCTT
CCCCACCTGCTTCCCCCCAGAGTCTGGCCTTCGGCTCCTGGCTGCCATCTGCTTATTGCTCCTCACATGGGTCAACTGTTCCAGTGTGCG
GTGGGCCACCCGGGTTCAAGACATCTTCACAGCTGGGAAGCTCCTGGCCTTGGCCCTGATTATCATCATGGGGATTGTACAGATATGCAA
AGGAGAGTACTTCTGGCTGGAGCCAAAGAATGCATTTGAGAATTTCCAGGAACCTGACATCGGCCTCGTCGCACTGGCTTTCCTTCAGGG
CTCCTTTGCCTATGGAGGCTGGAACTTTCTGAATTACGTGACTGAGGAGCTTGTTGATCCCTACAAGAACCTTCCCAGAGCCATCTTCAT
CTCCATCCCACTGGTCACATTTGTGTATGTCTTTGCCAATGTCGCTTATGTCACTGCAATGTCCCCCCAGGAGCTGCTGGCATCCAACGC
CGTCGCTGTGACTTTTGGAGAGAAGCTCCTAGGAGTCATGGCCTGGATCATGCCCATTTCTGTTGCCCTGTCCACATTTGGAGGAGTTAA
TGGGTCTCTCTTCACCTCCTCTCGGCTGTTCTTCGCTGGAGCCCGAGAGGGCCACCTTCCCAGTGTGTTGGCCATGATCCACGTGAAGCG
CTGCACCCCAATCCCAGCCCTGCTCTTCACATGCATCTCCACCCTGCTGATGCTGGTCACCAGCGACATGTACACACTCATCAACTATGT
GGGCTTCATCAACTACCTCTTCTATGGGGTCACGGTTGCTGGACAGATAGTCCTTCGCTGGAAGAAGCCTGATATCCCCCGCCCCATCAA
GATCAACCTGCTGTTCCCCATCATCTACTTGCTGTTCTGGGCCTTCCTGCTGGTCTTCAGCCTGTGGTCAGAGCCGGTGGTGTGTGGCAT
TGGCCTGGCCATCATGCTGACAGGAGTGCCTGTCTATTTCCTGGGTGTTTACTGGCAACACAAGCCCAAGTGTTTCAGTGACTTCATTGA
GCTGCTAACCCTGGTGAGCCAGAAGATGTGTGTGGTCGTGTACCCCGAGGTGGAGCGGGGCTCAGGGACAGAGGAGGCTAATGAGGACAT
GGAGGAGCAGCAGCAGCCCATGTACCAACCCACTCCCACGAAGGACAAGGACGTGGCGGGGCAGCCCCAGCCCTGAGGACCACCATTCCC
TGGCTACTCTCTCCTTCCTCCCCCTTTTATCCTACCTCCCTGCCTTGGTCCTGCCAACACATGCGAGTACACACACACCCCTCTCTCTGC
TTTTGTCAGGCAGTGGTAGGACTTTGGTGTGGGTGGTGAGAAATTGTAAACAAAAACTGACATTCATACCCAAAGAACCAGCCTCTCACC
CCAGGGTCCATGTCCCAGGCCCCACTCCAGTGCTGCCCACACTCCCAGCTGCTGGAGGAGAGGGGAGATGCCAAGGTGCCCTGCAGGACC
TCCCTCCGGGCCACACCCTCAGCTGCCTCTTCAGGAACCGGAGCTCATTACTGCCTTCCCTCCCAGGGAGGCCCCTTCAGAGAGGAGAGG
CCACAGGAGCTGCATTGTGGGGGGACAGGCTCAAGCAATTCTGTCCCCATCAAGGGGTCAGCTGGAGAGACCCAAGACCCTATCTGTTCA
CCAGGGACCCAAAATCCAAGGGGATGCTTCCCTCTGCCCTCTTTCCTGCCCCTCCCCATCATACCTGCACCCACCCCAGCCAGGGCTCCC
TGTCCAGAATTCGGTTCTCCTCAGGACGCCAACTCCCAGAGCTAAGGACCAAGGAGAAGAACAGCCTCTCCACCCCCAAGCCAGGCGGTT
GAGGAACATATTGAGAAAGGTTCAGATTGCAGAAACCCAGCCCTGCCCCTGCCTCCTGCATCCAGCCCCCAACATGGTGCCAAAGCTTCC
AGAAGCCAAAAAGCTTCTGATTTTTAAGGTAGTGGGCATCTCTCTCCTAATGACGAAGCTGCTCAGCAACTCCACCTGCCCGCCGCAGGA
AGGAGCAGTCCCCTGCTATCCCTGCAGCCACTCCCAGCACACCCGCACACAGCCAGCACCACCGCCCCCACCGTGCACTTCTCCTCTCTG
GGCCTTGGCTTGGGACCAGGTACGAAGGATCCCCAAGCCCTTCAGGCCTGAGATCAGAGCCAGATCAGCCTTAAGTCACCTCCCATCCAA
GAACTTGGCCTAAAAATACTCCCCTATTTCTAACCCTCAGGACGGATCTGATATTAAATGCCTTCCCTGGGAGGAAGGGTGCTTTCCCCC
TCCCTAGAGGTGCCCATTCCATACCCTGGGAGACTGAGGAGAGCATTGGCTGAAGCCCAGTTCCTTTCCCATCCATCCCCAACTCCAATA
ATCCCCCACTCCTCGCAGGTCTCAGTGTCATGCTGTCTTGGGGCAGGGTGAAAGGGTAGTGGCAGCAGGGCGCCCACTCTGGAGATCCTC
AAAAAAGGCCCTCCTCTGTGGCTGGCAGCCTCTGACCTTTCCCTGGGCTTCAAAGGAAGGCTATGGAGTTTGCTGTGGGCCCTGCAACCT
TCCCAGCCACTCCTGCTGCACTAAGGACTTAGGATCCTTTTATCACAAATCGGGATTCTCTCCCCCACCCCGAATTCTGTCTGCTTAAAC
TGGAATACACAGGAGCCCTTCCTGGCCTGGATGGTGTCTCCCAGCTTCCCCGCCCAGCTTGCCCACCCCATAGTTGGTGAGATGCCAAGT
TTGGTCTGAGTTGTGACCCCTTCAGAGTAGATGCCCGGCAGGCTGGGGTTGGCCCCTGGAGGGTCAGGGGACCATCTTCTTATTCCCTCT
TTTCTCATTCCTCCAACTTCCTCCCCTCCTTCAATTATTTTTTTGTAAAGTTGATGCCTTACTTTTTGGATAAATATTTTTGAAGCTGGT
ATTTCTATTTCTTTTGGATTTTTTTTAATGTAAGGTTGTTTTGGGGGATGGAGTTAGAACCTTAATGATAATTTCTTTCGTTTGGTGTAG

>4864_4864_9_ANO1-SLC7A8_ANO1_chr11_70017145_ENST00000538023_SLC7A8_chr14_23635749_ENST00000316902_length(amino acids)=1268AA_BP=783
MRVNEKYSTLPAEDRSVHIINICAIEDIGYLPSEGTLLNSLSVDPDAECKYGLYFRDGRRKVDYILVYHHKRPSGNRTLVRRVQHSDTPS
GARSVKQDHPLPGKGASLDAGSGEPPMDYHEDDKRFRREEYEGNLLEAGLELERDEDTKIHGVGFVKIHAPWNVLCREAEFLKLKMPTKK
MYHINETRGLLKKINSVLQKITDPIQPKVAEHRPQTMKRLSYPFSREKQHLFDLSDKDSFFDSKTRSTIVYEILKRTTCTKAKYSMGITS
LLANGVYAAAYPLHDGDYNGENVEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEKIGLYFAWLGVYTQMLIPASIVGIIVFLYGCATM
DENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMALWAATFMEHWKRKQMRLNYRWDLTGFEEEEKAL
LDHPRAEYEARVLEKSLKKESRNKEKRRHIPEESTNKWKQRVKTAMAGVKLTDKVKLTWRDRFPAYLTNLVSIIFMIAVTFAIVLGVIIY
RISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKG
RFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECVKRKQRYEVDYNLE
PFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAVRAKDIGNIIGSGIFVSPKGVLENAGSVGLALI
VWIVTGFITVVGALCYAELGVTIPKSGGDYSYVKDIFGGLAGFLRLWIAVLVIYPTNQAVIALTFSNYVLQPLFPTCFPPESGLRLLAAI
CLLLLTWVNCSSVRWATRVQDIFTAGKLLALALIIIMGIVQICKGEYFWLEPKNAFENFQEPDIGLVALAFLQGSFAYGGWNFLNYVTEE
LVDPYKNLPRAIFISIPLVTFVYVFANVAYVTAMSPQELLASNAVAVTFGEKLLGVMAWIMPISVALSTFGGVNGSLFTSSRLFFAGARE
GHLPSVLAMIHVKRCTPIPALLFTCISTLLMLVTSDMYTLINYVGFINYLFYGVTVAGQIVLRWKKPDIPRPIKINLLFPIIYLLFWAFL
LVFSLWSEPVVCGIGLAIMLTGVPVYFLGVYWQHKPKCFSDFIELLTLVSQKMCVVVYPEVERGSGTEEANEDMEEQQQPMYQPTPTKDK

--------------------------------------------------------------
>4864_4864_10_ANO1-SLC7A8_ANO1_chr11_70017145_ENST00000538023_SLC7A8_chr14_23635749_ENST00000469263_length(transcript)=5078nt_BP=2399nt
GGATGGGGAGGGCGCGCCGCCCGGCGGTCCCAGCGCACAGGCGGCCACGATGAGGGTCAACGAGAAGTACTCGACGCTCCCGGCCGAGGA
CCGCAGCGTCCACATCATCAACATCTGCGCCATCGAGGACATCGGCTACCTGCCGTCCGAGGGCACGCTGCTGAACTCCTTATCTGTGGA
CCCTGATGCCGAGTGCAAGTATGGCCTGTACTTCAGGGACGGCCGGCGCAAGGTGGACTACATCCTGGTGTACCATCACAAGAGGCCCTC
GGGCAACCGGACCCTGGTCAGGAGGGTGCAGCACAGCGACACCCCCTCTGGGGCTCGCAGCGTCAAGCAGGACCACCCCCTGCCGGGCAA
GGGGGCGTCGCTGGATGCAGGCTCGGGGGAGCCCCCGATGGACTACCACGAGGATGACAAGCGCTTCCGCAGGGAGGAGTACGAGGGCAA
CCTCCTGGAGGCGGGCCTGGAGCTGGAGCGGGACGAGGACACTAAAATCCACGGAGTCGGGTTTGTGAAAATCCATGCCCCCTGGAACGT
GCTGTGCAGAGAGGCCGAGTTTCTGAAACTGAAGATGCCGACGAAGAAGATGTACCACATTAATGAGACCCGTGGCCTCCTGAAAAAAAT
CAACTCTGTGCTCCAGAAAATCACAGATCCCATCCAGCCCAAAGTGGCTGAGCACAGGCCCCAGACCATGAAGAGACTCTCCTATCCCTT
CTCCCGGGAGAAGCAGCATCTATTTGACTTGTCTGATAAGGATTCCTTTTTCGACAGCAAAACCCGGAGCACGATTGTCTATGAGATCTT
GAAGAGAACGACGTGTACAAAGGCCAAGTACAGCATGGGCATCACGAGCCTGCTGGCCAATGGTGTGTACGCGGCTGCATACCCACTGCA
CGATGGAGACTACAACGGTGAAAACGTCGAGTTCAACGACAGAAAACTCCTGTACGAAGAGTGGGCACGCTATGGAGTTTTCTATAAGTA
CCAGCCCATCGACCTGGTCAGGAAGTATTTTGGGGAGAAGATCGGCCTGTACTTCGCCTGGCTGGGCGTGTACACCCAGATGCTCATCCC
TGCCTCCATCGTGGGAATCATTGTCTTCCTGTACGGATGCGCCACCATGGATGAAAACATCCCCAGCATGGAGATGTGTGACCAGAGACA
CAATATCACCATGTGCCCGCTTTGCGACAAGACCTGCAGCTACTGGAAGATGAGCTCAGCCTGCGCCACGGCCCGCGCCAGCCACCTCTT
CGACAACCCCGCCACGGTCTTCTTCTCTGTCTTCATGGCCCTCTGGGCTGCCACCTTCATGGAGCACTGGAAGCGGAAACAGATGCGACT
CAACTACCGCTGGGACCTCACGGGCTTTGAAGAGGAAGAGAAAGCACTTCTGGATCATCCTAGAGCTGAATACGAAGCCAGAGTCTTGGA
GAAGTCTCTGAAGAAAGAGTCCAGAAACAAAGAGAAGCGCCGGCATATTCCAGAGGAGTCAACAAACAAATGGAAGCAGAGGGTTAAGAC
AGCCATGGCGGGGGTGAAATTGACTGACAAAGTGAAGCTGACATGGAGAGATCGGTTCCCAGCCTACCTCACTAACTTGGTCTCCATCAT
CTTCATGATTGCAGTGACGTTTGCCATCGTCCTCGGCGTCATCATCTACAGAATCTCCATGGCCGCCGCCTTGGCCATGAACTCCTCCCC
CTCCGTGCGGTCCAACATCCGGGTCACAGTCACAGCCACCGCAGTCATCATCAACCTAGTGGTCATCATCCTCCTGGACGAGGTGTATGG
CTGCATAGCCCGATGGCTCACCAAGATCGAGGTCCCAAAGACGGAGAAAAGCTTTGAGGAGAGGCTGATCTTCAAGGCTTTCCTGCTGAA
GTTTGTGAATTCCTACACCCCCATCTTTTACGTGGCGTTCTTCAAAGGCCGGTTTGTTGGACGCCCGGGCGACTACGTGTACATTTTCCG
TTCCTTCCGAATGGAAGAGTGTGCGCCAGGGGGCTGCCTGATGGAGCTATGCATCCAGCTCAGCATCATCATGCTGGGGAAACAGCTGAT
CCAGAACAACCTGTTCGAGATCGGCATCCCGAAGATGAAGAAGCTCATCCGCTACCTGAAGCTGAAGCAGCAGAGCCCCCCTGACCACGA
GGAGTGTGTGAAGAGGAAACAGCGGTACGAGGTGGATTACAACCTGGAGCCCTTCGCGGGCCTCACCCCAGAGTACATGGAAATGATCAT
CCAGTTTGGCTTCGTCACCCTGTTTGTCGCCTCCTTCCCCCTGGCCCCACTGTTTGCGCTGCTGAACAACATCATCGAGATCCGCCTGGA
CGCCAAAAAGTTTGTCACTGAGCTCCGAAGGCCGGTAGCTGTCAGAGCCAAAGACATCGGGAACATCATCGGCTCTGGAATCTTTGTCTC
GCCAAAGGGAGTGCTGGAGAATGCTGGTTCTGTGGGCCTTGCTCTCATCGTCTGGATTGTGACGGGCTTCATCACAGTTGTGGGAGCCCT
CTGCTATGCTGAACTCGGGGTCACCATCCCCAAATCTGGAGGTGACTACTCCTATGTCAAGGACATCTTCGGAGGACTGGCTGGGTTCCT
GAGGCTGTGGATTGCTGTGCTGGTGATCTACCCCACCAACCAGGCTGTCATCGCCCTCACCTTCTCCAACTACGTGCTGCAGCCGCTCTT
CCCCACCTGCTTCCCCCCAGAGTCTGGCCTTCGGCTCCTGGCTGCCATCTGCTTATTGCTCCTCACATGGGTCAACTGTTCCAGTGTGCG
GTGGGCCACCCGGGTTCAAGACATCTTCACAGCTGGGAAGCTCCTGGCCTTGGCCCTGATTATCATCATGGGGATTGTACAGATATGCAA
AGGAGAGTACTTCTGGCTGGAGCCAAAGAATGCATTTGAGAATTTCCAGGAACCTGACATCGGCCTCGTCGCACTGGCTTTCCTTCAGGG
CTCCTTTGCCTATGGAGGCTGGAACTTTCTGAATTACGTGACTGAGGAGCTTGTTGATCCCTACAAAGCTGCTAACCCTGGTGAGCCAGA
AGATGTGTGTGGTCGTGTACCCCGAGGTGGAGCGGGGCTCAGGGACAGAGGAGGCTAATGAGGACATGGAGGAGCAGCAGCAGCCCATGT
ACCAACCCACTCCCACGAAGGACAAGGACGTGGCGGGGCAGCCCCAGCCCTGAGGACCACCATTCCCTGGCTACTCTCTCCTTCCTCCCC
CTTTTATCCTACCTCCCTGCCTTGGTCCTGCCAACACATGCGAGTACACACACACCCCTCTCTCTGCTTTTGTCAGGCAGTGGTAGGACT
TTGGTGTGGGTGGTGAGAAATTGTAAACAAAAACTGACATTCATACCCAAAGAACCAGCCTCTCACCCCAGGGTCCATGTCCCAGGCCCC
ACTCCAGTGCTGCCCACACTCCCAGCTGCTGGAGGAGAGGGGAGATGCCAAGGTGCCCTGCAGGACCTCCCTCCGGGCCACACCCTCAGC
TGCCTCTTCAGGAACCGGAGCTCATTACTGCCTTCCCTCCCAGGGAGGCCCCTTCAGAGAGGAGAGGCCACAGGAGCTGCATTGTGGGGG
GACAGGCTCAAGCAATTCTGTCCCCATCAAGGGGTCAGCTGGAGAGACCCAAGACCCTATCTGTTCACCAGGGACCCAAAATCCAAGGGG
ATGCTTCCCTCTGCCCTCTTTCCTGCCCCTCCCCATCATACCTGCACCCACCCCAGCCAGGGCTCCCTGTCCAGAATTCGGTTCTCCTCA
GGACGCCAACTCCCAGAGCTAAGGACCAAGGAGAAGAACAGCCTCTCCACCCCCAAGCCAGGCGGTTGAGGAACATATTGAGAAAGGTTC
AGATTGCAGAAACCCAGCCCTGCCCCTGCCTCCTGCATCCAGCCCCCAACATGGTGCCAAAGCTTCCAGAAGCCAAAAAGCTTCTGATTT
TTAAGGTAGTGGGCATCTCTCTCCTAATGACGAAGCTGCTCAGCAACTCCACCTGCCCGCCGCAGGAAGGAGCAGTCCCCTGCTATCCCT
GCAGCCACTCCCAGCACACCCGCACACAGCCAGCACCACCGCCCCCACCGTGCACTTCTCCTCTCTGGGCCTTGGCTTGGGACCAGGTAC
GAAGGATCCCCAAGCCCTTCAGGCCTGAGATCAGAGCCAGATCAGCCTTAAGTCACCTCCCATCCAAGAACTTGGCCTAAAAATACTCCC
CTATTTCTAACCCTCAGGACGGATCTGATATTAAATGCCTTCCCTGGGAGGAAGGGTGCTTTCCCCCTCCCTAGAGGTGCCCATTCCATA
CCCTGGGAGACTGAGGAGAGCATTGGCTGAAGCCCAGTTCCTTTCCCATCCATCCCCAACTCCAATAATCCCCCACTCCTCGCAGGTCTC
AGTGTCATGCTGTCTTGGGGCAGGGTGAAAGGGTAGTGGCAGCAGGGCGCCCACTCTGGAGATCCTCAAAAAAGGCCCTCCTCTGTGGCT
GGCAGCCTCTGACCTTTCCCTGGGCTTCAAAGGAAGGCTATGGAGTTTGCTGTGGGCCCTGCAACCTTCCCAGCCACTCCTGCTGCACTA
AGGACTTAGGATCCTTTTATCACAAATCGGGATTCTCTCCCCCACCCCGAATTCTGTCTGCTTAAACTGGAATACACAGGAGCCCTTCCT
GGCCTGGATGGTGTCTCCCAGCTTCCCCGCCCAGCTTGCCCACCCCATAGTTGGTGAGATGCCAAGTTTGGTCTGAGTTGTGACCCCTTC
AGAGTAGATGCCCGGCAGGCTGGGGTTGGCCCCTGGAGGGTCAGGGGACCATCTTCTTATTCCCTCTTTTCTCATTCCTCCAACTTCCTC
CCCTCCTTCAATTATTTTTTTGTAAAGTTGATGCCTTACTTTTTGGATAAATATTTTTGAAGCTGGTATTTCTATTTCTTTTGGATTTTT
TTTAATGTAAGGTTGTTTTGGGGGATGGAGTTAGAACCTTAATGATAATTTCTTTCGTTTGGTGTAGGTTTTAGAGATTTGTTTTGTGGA

>4864_4864_10_ANO1-SLC7A8_ANO1_chr11_70017145_ENST00000538023_SLC7A8_chr14_23635749_ENST00000469263_length(amino acids)=1022AA_BP=783
MRVNEKYSTLPAEDRSVHIINICAIEDIGYLPSEGTLLNSLSVDPDAECKYGLYFRDGRRKVDYILVYHHKRPSGNRTLVRRVQHSDTPS
GARSVKQDHPLPGKGASLDAGSGEPPMDYHEDDKRFRREEYEGNLLEAGLELERDEDTKIHGVGFVKIHAPWNVLCREAEFLKLKMPTKK
MYHINETRGLLKKINSVLQKITDPIQPKVAEHRPQTMKRLSYPFSREKQHLFDLSDKDSFFDSKTRSTIVYEILKRTTCTKAKYSMGITS
LLANGVYAAAYPLHDGDYNGENVEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEKIGLYFAWLGVYTQMLIPASIVGIIVFLYGCATM
DENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMALWAATFMEHWKRKQMRLNYRWDLTGFEEEEKAL
LDHPRAEYEARVLEKSLKKESRNKEKRRHIPEESTNKWKQRVKTAMAGVKLTDKVKLTWRDRFPAYLTNLVSIIFMIAVTFAIVLGVIIY
RISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKG
RFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECVKRKQRYEVDYNLE
PFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAVRAKDIGNIIGSGIFVSPKGVLENAGSVGLALI
VWIVTGFITVVGALCYAELGVTIPKSGGDYSYVKDIFGGLAGFLRLWIAVLVIYPTNQAVIALTFSNYVLQPLFPTCFPPESGLRLLAAI
CLLLLTWVNCSSVRWATRVQDIFTAGKLLALALIIIMGIVQICKGEYFWLEPKNAFENFQEPDIGLVALAFLQGSFAYGGWNFLNYVTEE

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Fusion Gene PPI Analysis for ANO1-SLC7A8


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ANO1-SLC7A8


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ANO1-SLC7A8


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneC0014175Endometriosis1CTD_human
TgeneC0269102Endometrioma1CTD_human