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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:DNAJC17-ZFYVE19 (FusionGDB2 ID:HG55192TG84936)

Fusion Gene Summary for DNAJC17-ZFYVE19

check button Fusion gene summary
Fusion gene informationFusion gene name: DNAJC17-ZFYVE19
Fusion gene ID: hg55192tg84936
HgeneTgene
Gene symbol

DNAJC17

ZFYVE19

Gene ID

55192

84936

Gene nameDnaJ heat shock protein family (Hsp40) member C17zinc finger FYVE-type containing 19
Synonyms-ANCHR|MPFYVE
Cytomap('DNAJC17')('ZFYVE19')

15q15.1

15q15.1

Type of geneprotein-codingprotein-coding
DescriptiondnaJ homolog subfamily C member 17DnaJ (Hsp40) homolog, subfamily C, member 17abscission/NoCut checkpoint regulatorMLL partner containing FYVE domainzinc finger FYVE domain-containing protein 19zinc finger, FYVE domain containing 19
Modification date2020031320200313
UniProtAcc

Q9NVM6

.
Ensembl transtripts involved in fusion geneENST00000220496, ENST00000558727, 
Fusion gene scores* DoF score8 X 7 X 7=3927 X 8 X 6=336
# samples 138
** MAII scorelog2(13/392*10)=-1.59234203108675
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(8/336*10)=-2.0703893278914
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: DNAJC17 [Title/Abstract] AND ZFYVE19 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointDNAJC17(41071420)-ZFYVE19(41104896), # samples:1
DNAJC17(41071420)-ZFYVE19(41105535), # samples:1
DNAJC17(41071421)-ZFYVE19(41105536), # samples:1
DNAJC17(41071421)-ZFYVE19(41104897), # samples:1
Anticipated loss of major functional domain due to fusion event.DNAJC17-ZFYVE19 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
DNAJC17-ZFYVE19 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
DNAJC17-ZFYVE19 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
DNAJC17-ZFYVE19 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across DNAJC17 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across ZFYVE19 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LIHCTCGA-G3-A25T-01ADNAJC17chr15

41071421

-ZFYVE19chr15

41104897

+
ChimerDB4LIHCTCGA-G3-A25T-01ADNAJC17chr15

41071421

-ZFYVE19chr15

41105536

+
ChimerDB4LIHCTCGA-G3-A25TDNAJC17chr15

41071420

-ZFYVE19chr15

41104896

+
ChimerDB4LIHCTCGA-G3-A25TDNAJC17chr15

41071420

-ZFYVE19chr15

41105535

+


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Fusion Gene ORF analysis for DNAJC17-ZFYVE19

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000220496ENST00000299173DNAJC17chr15

41071421

-ZFYVE19chr15

41104897

+
5CDS-intronENST00000220496ENST00000299173DNAJC17chr15

41071420

-ZFYVE19chr15

41104896

+
5CDS-intronENST00000220496ENST00000563530DNAJC17chr15

41071421

-ZFYVE19chr15

41104897

+
5CDS-intronENST00000220496ENST00000563530DNAJC17chr15

41071421

-ZFYVE19chr15

41105536

+
5CDS-intronENST00000220496ENST00000563530DNAJC17chr15

41071420

-ZFYVE19chr15

41104896

+
5CDS-intronENST00000220496ENST00000563530DNAJC17chr15

41071420

-ZFYVE19chr15

41105535

+
In-frameENST00000220496ENST00000299173DNAJC17chr15

41071421

-ZFYVE19chr15

41105536

+
In-frameENST00000220496ENST00000299173DNAJC17chr15

41071420

-ZFYVE19chr15

41105535

+
In-frameENST00000220496ENST00000336455DNAJC17chr15

41071421

-ZFYVE19chr15

41104897

+
In-frameENST00000220496ENST00000336455DNAJC17chr15

41071421

-ZFYVE19chr15

41105536

+
In-frameENST00000220496ENST00000336455DNAJC17chr15

41071420

-ZFYVE19chr15

41104896

+
In-frameENST00000220496ENST00000336455DNAJC17chr15

41071420

-ZFYVE19chr15

41105535

+
In-frameENST00000220496ENST00000355341DNAJC17chr15

41071421

-ZFYVE19chr15

41104897

+
In-frameENST00000220496ENST00000355341DNAJC17chr15

41071421

-ZFYVE19chr15

41105536

+
In-frameENST00000220496ENST00000355341DNAJC17chr15

41071420

-ZFYVE19chr15

41104896

+
In-frameENST00000220496ENST00000355341DNAJC17chr15

41071420

-ZFYVE19chr15

41105535

+
In-frameENST00000220496ENST00000564258DNAJC17chr15

41071421

-ZFYVE19chr15

41104897

+
In-frameENST00000220496ENST00000564258DNAJC17chr15

41071421

-ZFYVE19chr15

41105536

+
In-frameENST00000220496ENST00000564258DNAJC17chr15

41071420

-ZFYVE19chr15

41104896

+
In-frameENST00000220496ENST00000564258DNAJC17chr15

41071420

-ZFYVE19chr15

41105535

+
In-frameENST00000220496ENST00000570108DNAJC17chr15

41071421

-ZFYVE19chr15

41104897

+
In-frameENST00000220496ENST00000570108DNAJC17chr15

41071421

-ZFYVE19chr15

41105536

+
In-frameENST00000220496ENST00000570108DNAJC17chr15

41071420

-ZFYVE19chr15

41104896

+
In-frameENST00000220496ENST00000570108DNAJC17chr15

41071420

-ZFYVE19chr15

41105535

+
intron-3CDSENST00000558727ENST00000299173DNAJC17chr15

41071421

-ZFYVE19chr15

41105536

+
intron-3CDSENST00000558727ENST00000299173DNAJC17chr15

41071420

-ZFYVE19chr15

41105535

+
intron-3CDSENST00000558727ENST00000336455DNAJC17chr15

41071421

-ZFYVE19chr15

41104897

+
intron-3CDSENST00000558727ENST00000336455DNAJC17chr15

41071421

-ZFYVE19chr15

41105536

+
intron-3CDSENST00000558727ENST00000336455DNAJC17chr15

41071420

-ZFYVE19chr15

41104896

+
intron-3CDSENST00000558727ENST00000336455DNAJC17chr15

41071420

-ZFYVE19chr15

41105535

+
intron-3CDSENST00000558727ENST00000355341DNAJC17chr15

41071421

-ZFYVE19chr15

41104897

+
intron-3CDSENST00000558727ENST00000355341DNAJC17chr15

41071421

-ZFYVE19chr15

41105536

+
intron-3CDSENST00000558727ENST00000355341DNAJC17chr15

41071420

-ZFYVE19chr15

41104896

+
intron-3CDSENST00000558727ENST00000355341DNAJC17chr15

41071420

-ZFYVE19chr15

41105535

+
intron-3CDSENST00000558727ENST00000564258DNAJC17chr15

41071421

-ZFYVE19chr15

41104897

+
intron-3CDSENST00000558727ENST00000564258DNAJC17chr15

41071421

-ZFYVE19chr15

41105536

+
intron-3CDSENST00000558727ENST00000564258DNAJC17chr15

41071420

-ZFYVE19chr15

41104896

+
intron-3CDSENST00000558727ENST00000564258DNAJC17chr15

41071420

-ZFYVE19chr15

41105535

+
intron-3CDSENST00000558727ENST00000570108DNAJC17chr15

41071421

-ZFYVE19chr15

41104897

+
intron-3CDSENST00000558727ENST00000570108DNAJC17chr15

41071421

-ZFYVE19chr15

41105536

+
intron-3CDSENST00000558727ENST00000570108DNAJC17chr15

41071420

-ZFYVE19chr15

41104896

+
intron-3CDSENST00000558727ENST00000570108DNAJC17chr15

41071420

-ZFYVE19chr15

41105535

+
intron-intronENST00000558727ENST00000299173DNAJC17chr15

41071421

-ZFYVE19chr15

41104897

+
intron-intronENST00000558727ENST00000299173DNAJC17chr15

41071420

-ZFYVE19chr15

41104896

+
intron-intronENST00000558727ENST00000563530DNAJC17chr15

41071421

-ZFYVE19chr15

41104897

+
intron-intronENST00000558727ENST00000563530DNAJC17chr15

41071421

-ZFYVE19chr15

41105536

+
intron-intronENST00000558727ENST00000563530DNAJC17chr15

41071420

-ZFYVE19chr15

41104896

+
intron-intronENST00000558727ENST00000563530DNAJC17chr15

41071420

-ZFYVE19chr15

41105535

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)
BP loci
(transcript)
Predicted start
(transcript)
Predicted stop
(transcript)
Seq length
(amino acids)

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score

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Fusion Genomic Features for DNAJC17-ZFYVE19


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
DNAJC17chr1541071420-ZFYVE19chr1541104896+6.04E-050.99993956
DNAJC17chr1541071420-ZFYVE19chr1541104896+6.04E-050.99993956
DNAJC17chr1541071420-ZFYVE19chr1541105535+2.49E-101
DNAJC17chr1541071420-ZFYVE19chr1541105535+2.49E-101
DNAJC17chr1541071420-ZFYVE19chr1541104896+6.04E-050.99993956
DNAJC17chr1541071420-ZFYVE19chr1541104896+6.04E-050.99993956
DNAJC17chr1541071420-ZFYVE19chr1541105535+2.49E-101
DNAJC17chr1541071420-ZFYVE19chr1541105535+2.49E-101

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for DNAJC17-ZFYVE19


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr15:41071420/chr15:41104896)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
DNAJC17

Q9NVM6

.
FUNCTION: May negatively affect PAX8-induced thyroglobulin/TG transcription. {ECO:0000250|UniProtKB:Q91WT4}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneDNAJC17chr15:41071420chr15:41104896ENST00000220496-41111_7698305.0DomainJ
HgeneDNAJC17chr15:41071420chr15:41105535ENST00000220496-41111_7698305.0DomainJ
HgeneDNAJC17chr15:41071421chr15:41104897ENST00000220496-41111_7698305.0DomainJ
HgeneDNAJC17chr15:41071421chr15:41105536ENST00000220496-41111_7698305.0DomainJ
TgeneZFYVE19chr15:41071420chr15:41104896ENST00000299173010311_3750404.0Coiled coilOntology_term=ECO:0000255
TgeneZFYVE19chr15:41071420chr15:41104896ENST00000336455612311_375265462.0Coiled coilOntology_term=ECO:0000255
TgeneZFYVE19chr15:41071420chr15:41104896ENST00000355341511311_375275472.0Coiled coilOntology_term=ECO:0000255
TgeneZFYVE19chr15:41071420chr15:41104896ENST00000564258511311_375100297.0Coiled coilOntology_term=ECO:0000255
TgeneZFYVE19chr15:41071420chr15:41105535ENST00000299173510311_375275404.0Coiled coilOntology_term=ECO:0000255
TgeneZFYVE19chr15:41071420chr15:41105535ENST00000564258611311_375168297.0Coiled coilOntology_term=ECO:0000255
TgeneZFYVE19chr15:41071421chr15:41104897ENST00000299173010311_3750404.0Coiled coilOntology_term=ECO:0000255
TgeneZFYVE19chr15:41071421chr15:41104897ENST00000336455612311_375265462.0Coiled coilOntology_term=ECO:0000255
TgeneZFYVE19chr15:41071421chr15:41104897ENST00000355341511311_375275472.0Coiled coilOntology_term=ECO:0000255
TgeneZFYVE19chr15:41071421chr15:41104897ENST00000564258511311_375100297.0Coiled coilOntology_term=ECO:0000255
TgeneZFYVE19chr15:41071421chr15:41105536ENST00000299173510311_375275404.0Coiled coilOntology_term=ECO:0000255
TgeneZFYVE19chr15:41071421chr15:41105536ENST00000564258611311_375168297.0Coiled coilOntology_term=ECO:0000255
TgeneZFYVE19chr15:41071420chr15:41104896ENST00000299173010412_4170404.0Compositional biasNote=Poly-Glu
TgeneZFYVE19chr15:41071420chr15:41104896ENST00000299173010421_4440404.0Compositional biasNote=Cys-rich
TgeneZFYVE19chr15:41071420chr15:41104896ENST00000336455612412_417265462.0Compositional biasNote=Poly-Glu
TgeneZFYVE19chr15:41071420chr15:41104896ENST00000336455612421_444265462.0Compositional biasNote=Cys-rich
TgeneZFYVE19chr15:41071420chr15:41104896ENST00000355341511412_417275472.0Compositional biasNote=Poly-Glu
TgeneZFYVE19chr15:41071420chr15:41104896ENST00000355341511421_444275472.0Compositional biasNote=Cys-rich
TgeneZFYVE19chr15:41071420chr15:41104896ENST00000564258511412_417100297.0Compositional biasNote=Poly-Glu
TgeneZFYVE19chr15:41071420chr15:41104896ENST00000564258511421_444100297.0Compositional biasNote=Cys-rich
TgeneZFYVE19chr15:41071420chr15:41105535ENST00000299173510412_417275404.0Compositional biasNote=Poly-Glu
TgeneZFYVE19chr15:41071420chr15:41105535ENST00000299173510421_444275404.0Compositional biasNote=Cys-rich
TgeneZFYVE19chr15:41071420chr15:41105535ENST00000336455712412_417333462.0Compositional biasNote=Poly-Glu
TgeneZFYVE19chr15:41071420chr15:41105535ENST00000336455712421_444333462.0Compositional biasNote=Cys-rich
TgeneZFYVE19chr15:41071420chr15:41105535ENST00000355341611412_417343472.0Compositional biasNote=Poly-Glu
TgeneZFYVE19chr15:41071420chr15:41105535ENST00000355341611421_444343472.0Compositional biasNote=Cys-rich
TgeneZFYVE19chr15:41071420chr15:41105535ENST00000564258611412_417168297.0Compositional biasNote=Poly-Glu
TgeneZFYVE19chr15:41071420chr15:41105535ENST00000564258611421_444168297.0Compositional biasNote=Cys-rich
TgeneZFYVE19chr15:41071421chr15:41104897ENST00000299173010412_4170404.0Compositional biasNote=Poly-Glu
TgeneZFYVE19chr15:41071421chr15:41104897ENST00000299173010421_4440404.0Compositional biasNote=Cys-rich
TgeneZFYVE19chr15:41071421chr15:41104897ENST00000336455612412_417265462.0Compositional biasNote=Poly-Glu
TgeneZFYVE19chr15:41071421chr15:41104897ENST00000336455612421_444265462.0Compositional biasNote=Cys-rich
TgeneZFYVE19chr15:41071421chr15:41104897ENST00000355341511412_417275472.0Compositional biasNote=Poly-Glu
TgeneZFYVE19chr15:41071421chr15:41104897ENST00000355341511421_444275472.0Compositional biasNote=Cys-rich
TgeneZFYVE19chr15:41071421chr15:41104897ENST00000564258511412_417100297.0Compositional biasNote=Poly-Glu
TgeneZFYVE19chr15:41071421chr15:41104897ENST00000564258511421_444100297.0Compositional biasNote=Cys-rich
TgeneZFYVE19chr15:41071421chr15:41105536ENST00000299173510412_417275404.0Compositional biasNote=Poly-Glu
TgeneZFYVE19chr15:41071421chr15:41105536ENST00000299173510421_444275404.0Compositional biasNote=Cys-rich
TgeneZFYVE19chr15:41071421chr15:41105536ENST00000336455712412_417333462.0Compositional biasNote=Poly-Glu
TgeneZFYVE19chr15:41071421chr15:41105536ENST00000336455712421_444333462.0Compositional biasNote=Cys-rich
TgeneZFYVE19chr15:41071421chr15:41105536ENST00000355341611412_417343472.0Compositional biasNote=Poly-Glu
TgeneZFYVE19chr15:41071421chr15:41105536ENST00000355341611421_444343472.0Compositional biasNote=Cys-rich
TgeneZFYVE19chr15:41071421chr15:41105536ENST00000564258611412_417168297.0Compositional biasNote=Poly-Glu
TgeneZFYVE19chr15:41071421chr15:41105536ENST00000564258611421_444168297.0Compositional biasNote=Cys-rich
TgeneZFYVE19chr15:41071420chr15:41104896ENST00000299173010174_1870404.0MotifNote=MIM1-A
TgeneZFYVE19chr15:41071420chr15:41104896ENST00000299173010326_3390404.0MotifNote=MIM1-B
TgeneZFYVE19chr15:41071420chr15:41104896ENST00000336455612326_339265462.0MotifNote=MIM1-B
TgeneZFYVE19chr15:41071420chr15:41104896ENST00000355341511326_339275472.0MotifNote=MIM1-B
TgeneZFYVE19chr15:41071420chr15:41104896ENST00000564258511174_187100297.0MotifNote=MIM1-A
TgeneZFYVE19chr15:41071420chr15:41104896ENST00000564258511326_339100297.0MotifNote=MIM1-B
TgeneZFYVE19chr15:41071420chr15:41105535ENST00000299173510326_339275404.0MotifNote=MIM1-B
TgeneZFYVE19chr15:41071420chr15:41105535ENST00000564258611174_187168297.0MotifNote=MIM1-A
TgeneZFYVE19chr15:41071420chr15:41105535ENST00000564258611326_339168297.0MotifNote=MIM1-B
TgeneZFYVE19chr15:41071421chr15:41104897ENST00000299173010174_1870404.0MotifNote=MIM1-A
TgeneZFYVE19chr15:41071421chr15:41104897ENST00000299173010326_3390404.0MotifNote=MIM1-B
TgeneZFYVE19chr15:41071421chr15:41104897ENST00000336455612326_339265462.0MotifNote=MIM1-B
TgeneZFYVE19chr15:41071421chr15:41104897ENST00000355341511326_339275472.0MotifNote=MIM1-B
TgeneZFYVE19chr15:41071421chr15:41104897ENST00000564258511174_187100297.0MotifNote=MIM1-A
TgeneZFYVE19chr15:41071421chr15:41104897ENST00000564258511326_339100297.0MotifNote=MIM1-B
TgeneZFYVE19chr15:41071421chr15:41105536ENST00000299173510326_339275404.0MotifNote=MIM1-B
TgeneZFYVE19chr15:41071421chr15:41105536ENST00000564258611174_187168297.0MotifNote=MIM1-A
TgeneZFYVE19chr15:41071421chr15:41105536ENST00000564258611326_339168297.0MotifNote=MIM1-B
TgeneZFYVE19chr15:41071420chr15:41104896ENST0000029917301074_1330404.0Zinc fingerFYVE-type
TgeneZFYVE19chr15:41071421chr15:41104897ENST0000029917301074_1330404.0Zinc fingerFYVE-type

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneDNAJC17chr15:41071420chr15:41104896ENST00000220496-411111_11798305.0Compositional biasNote=Poly-Glu
HgeneDNAJC17chr15:41071420chr15:41105535ENST00000220496-411111_11798305.0Compositional biasNote=Poly-Glu
HgeneDNAJC17chr15:41071421chr15:41104897ENST00000220496-411111_11798305.0Compositional biasNote=Poly-Glu
HgeneDNAJC17chr15:41071421chr15:41105536ENST00000220496-411111_11798305.0Compositional biasNote=Poly-Glu
HgeneDNAJC17chr15:41071420chr15:41104896ENST00000220496-411178_24998305.0DomainNote=RRM
HgeneDNAJC17chr15:41071420chr15:41105535ENST00000220496-411178_24998305.0DomainNote=RRM
HgeneDNAJC17chr15:41071421chr15:41104897ENST00000220496-411178_24998305.0DomainNote=RRM
HgeneDNAJC17chr15:41071421chr15:41105536ENST00000220496-411178_24998305.0DomainNote=RRM
TgeneZFYVE19chr15:41071420chr15:41105535ENST00000336455712311_375333462.0Coiled coilOntology_term=ECO:0000255
TgeneZFYVE19chr15:41071420chr15:41105535ENST00000355341611311_375343472.0Coiled coilOntology_term=ECO:0000255
TgeneZFYVE19chr15:41071421chr15:41105536ENST00000336455712311_375333462.0Coiled coilOntology_term=ECO:0000255
TgeneZFYVE19chr15:41071421chr15:41105536ENST00000355341611311_375343472.0Coiled coilOntology_term=ECO:0000255
TgeneZFYVE19chr15:41071420chr15:41104896ENST00000336455612174_187265462.0MotifNote=MIM1-A
TgeneZFYVE19chr15:41071420chr15:41104896ENST00000355341511174_187275472.0MotifNote=MIM1-A
TgeneZFYVE19chr15:41071420chr15:41105535ENST00000299173510174_187275404.0MotifNote=MIM1-A
TgeneZFYVE19chr15:41071420chr15:41105535ENST00000336455712174_187333462.0MotifNote=MIM1-A
TgeneZFYVE19chr15:41071420chr15:41105535ENST00000336455712326_339333462.0MotifNote=MIM1-B
TgeneZFYVE19chr15:41071420chr15:41105535ENST00000355341611174_187343472.0MotifNote=MIM1-A
TgeneZFYVE19chr15:41071420chr15:41105535ENST00000355341611326_339343472.0MotifNote=MIM1-B
TgeneZFYVE19chr15:41071421chr15:41104897ENST00000336455612174_187265462.0MotifNote=MIM1-A
TgeneZFYVE19chr15:41071421chr15:41104897ENST00000355341511174_187275472.0MotifNote=MIM1-A
TgeneZFYVE19chr15:41071421chr15:41105536ENST00000299173510174_187275404.0MotifNote=MIM1-A
TgeneZFYVE19chr15:41071421chr15:41105536ENST00000336455712174_187333462.0MotifNote=MIM1-A
TgeneZFYVE19chr15:41071421chr15:41105536ENST00000336455712326_339333462.0MotifNote=MIM1-B
TgeneZFYVE19chr15:41071421chr15:41105536ENST00000355341611174_187343472.0MotifNote=MIM1-A
TgeneZFYVE19chr15:41071421chr15:41105536ENST00000355341611326_339343472.0MotifNote=MIM1-B
TgeneZFYVE19chr15:41071420chr15:41104896ENST0000033645561274_133265462.0Zinc fingerFYVE-type
TgeneZFYVE19chr15:41071420chr15:41104896ENST0000035534151174_133275472.0Zinc fingerFYVE-type
TgeneZFYVE19chr15:41071420chr15:41104896ENST0000056425851174_133100297.0Zinc fingerFYVE-type
TgeneZFYVE19chr15:41071420chr15:41105535ENST0000029917351074_133275404.0Zinc fingerFYVE-type
TgeneZFYVE19chr15:41071420chr15:41105535ENST0000033645571274_133333462.0Zinc fingerFYVE-type
TgeneZFYVE19chr15:41071420chr15:41105535ENST0000035534161174_133343472.0Zinc fingerFYVE-type
TgeneZFYVE19chr15:41071420chr15:41105535ENST0000056425861174_133168297.0Zinc fingerFYVE-type
TgeneZFYVE19chr15:41071421chr15:41104897ENST0000033645561274_133265462.0Zinc fingerFYVE-type
TgeneZFYVE19chr15:41071421chr15:41104897ENST0000035534151174_133275472.0Zinc fingerFYVE-type
TgeneZFYVE19chr15:41071421chr15:41104897ENST0000056425851174_133100297.0Zinc fingerFYVE-type
TgeneZFYVE19chr15:41071421chr15:41105536ENST0000029917351074_133275404.0Zinc fingerFYVE-type
TgeneZFYVE19chr15:41071421chr15:41105536ENST0000033645571274_133333462.0Zinc fingerFYVE-type
TgeneZFYVE19chr15:41071421chr15:41105536ENST0000035534161174_133343472.0Zinc fingerFYVE-type
TgeneZFYVE19chr15:41071421chr15:41105536ENST0000056425861174_133168297.0Zinc fingerFYVE-type


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Fusion Gene Sequence for DNAJC17-ZFYVE19


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

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Fusion Gene PPI Analysis for DNAJC17-ZFYVE19


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for DNAJC17-ZFYVE19


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for DNAJC17-ZFYVE19


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource