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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ECHDC2-GTF2I (FusionGDB2 ID:HG55268TG2969)

Fusion Gene Summary for ECHDC2-GTF2I

check button Fusion gene summary
Fusion gene informationFusion gene name: ECHDC2-GTF2I
Fusion gene ID: hg55268tg2969
HgeneTgene
Gene symbol

ECHDC2

GTF2I

Gene ID

55268

2969

Gene nameenoyl-CoA hydratase domain containing 2general transcription factor IIi
Synonyms-BAP135|BTKAP1|DIWS|GTFII-I|IB291|SPIN|TFII-I|WBS|WBSCR6
Cytomap('ECHDC2')('GTF2I')

1p32.3

7q11.23

Type of geneprotein-codingprotein-coding
Descriptionenoyl-CoA hydratase domain-containing protein 2, mitochondrialenoyl Coenzyme A hydratase domain containing 2general transcription factor II-IBTK-associated protein, 135kDBruton tyrosine kinase-associated protein 135SRF-Phox1-interacting proteinWilliams-Beuren syndrome chromosome region 6
Modification date2020031320200313
UniProtAcc

Q86YB7

.
Ensembl transtripts involved in fusion geneENST00000358358, ENST00000371522, 
ENST00000536120, ENST00000541281, 
ENST00000480312, 
Fusion gene scores* DoF score12 X 8 X 6=57621 X 20 X 13=5460
# samples 1225
** MAII scorelog2(12/576*10)=-2.26303440583379
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(25/5460*10)=-4.44890095114513
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ECHDC2 [Title/Abstract] AND GTF2I [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointECHDC2(53373539)-GTF2I(74160675), # samples:1
Anticipated loss of major functional domain due to fusion event.ECHDC2-GTF2I seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ECHDC2-GTF2I seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ECHDC2-GTF2I seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
ECHDC2-GTF2I seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
ECHDC2-GTF2I seems lost the major protein functional domain in Tgene partner, which is a epigenetic factor due to the frame-shifted ORF.
ECHDC2-GTF2I seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
ECHDC2-GTF2I seems lost the major protein functional domain in Tgene partner, which is a transcription factor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneGTF2I

GO:0016525

negative regulation of angiogenesis

19242469


check buttonFusion gene breakpoints across ECHDC2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across GTF2I (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4ACCTCGA-OR-A5J6ECHDC2chr1

53373539

-GTF2Ichr7

74160675

+


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Fusion Gene ORF analysis for ECHDC2-GTF2I

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000358358ENST00000438130ECHDC2chr1

53373539

-GTF2Ichr7

74160675

+
5CDS-3UTRENST00000371522ENST00000438130ECHDC2chr1

53373539

-GTF2Ichr7

74160675

+
5CDS-3UTRENST00000536120ENST00000438130ECHDC2chr1

53373539

-GTF2Ichr7

74160675

+
5CDS-3UTRENST00000541281ENST00000438130ECHDC2chr1

53373539

-GTF2Ichr7

74160675

+
5CDS-intronENST00000358358ENST00000443166ECHDC2chr1

53373539

-GTF2Ichr7

74160675

+
5CDS-intronENST00000371522ENST00000443166ECHDC2chr1

53373539

-GTF2Ichr7

74160675

+
5CDS-intronENST00000536120ENST00000443166ECHDC2chr1

53373539

-GTF2Ichr7

74160675

+
5CDS-intronENST00000541281ENST00000443166ECHDC2chr1

53373539

-GTF2Ichr7

74160675

+
Frame-shiftENST00000536120ENST00000324896ECHDC2chr1

53373539

-GTF2Ichr7

74160675

+
Frame-shiftENST00000536120ENST00000346152ECHDC2chr1

53373539

-GTF2Ichr7

74160675

+
Frame-shiftENST00000536120ENST00000353920ECHDC2chr1

53373539

-GTF2Ichr7

74160675

+
Frame-shiftENST00000536120ENST00000416070ECHDC2chr1

53373539

-GTF2Ichr7

74160675

+
In-frameENST00000358358ENST00000324896ECHDC2chr1

53373539

-GTF2Ichr7

74160675

+
In-frameENST00000358358ENST00000346152ECHDC2chr1

53373539

-GTF2Ichr7

74160675

+
In-frameENST00000358358ENST00000353920ECHDC2chr1

53373539

-GTF2Ichr7

74160675

+
In-frameENST00000358358ENST00000416070ECHDC2chr1

53373539

-GTF2Ichr7

74160675

+
In-frameENST00000371522ENST00000324896ECHDC2chr1

53373539

-GTF2Ichr7

74160675

+
In-frameENST00000371522ENST00000346152ECHDC2chr1

53373539

-GTF2Ichr7

74160675

+
In-frameENST00000371522ENST00000353920ECHDC2chr1

53373539

-GTF2Ichr7

74160675

+
In-frameENST00000371522ENST00000416070ECHDC2chr1

53373539

-GTF2Ichr7

74160675

+
In-frameENST00000541281ENST00000324896ECHDC2chr1

53373539

-GTF2Ichr7

74160675

+
In-frameENST00000541281ENST00000346152ECHDC2chr1

53373539

-GTF2Ichr7

74160675

+
In-frameENST00000541281ENST00000353920ECHDC2chr1

53373539

-GTF2Ichr7

74160675

+
In-frameENST00000541281ENST00000416070ECHDC2chr1

53373539

-GTF2Ichr7

74160675

+
intron-3CDSENST00000480312ENST00000324896ECHDC2chr1

53373539

-GTF2Ichr7

74160675

+
intron-3CDSENST00000480312ENST00000346152ECHDC2chr1

53373539

-GTF2Ichr7

74160675

+
intron-3CDSENST00000480312ENST00000353920ECHDC2chr1

53373539

-GTF2Ichr7

74160675

+
intron-3CDSENST00000480312ENST00000416070ECHDC2chr1

53373539

-GTF2Ichr7

74160675

+
intron-3UTRENST00000480312ENST00000438130ECHDC2chr1

53373539

-GTF2Ichr7

74160675

+
intron-intronENST00000480312ENST00000443166ECHDC2chr1

53373539

-GTF2Ichr7

74160675

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000371522ECHDC2chr153373539-ENST00000324896GTF2Ichr774160675+2624458941461455
ENST00000371522ECHDC2chr153373539-ENST00000353920GTF2Ichr774160675+2624458941461455
ENST00000371522ECHDC2chr153373539-ENST00000346152GTF2Ichr774160675+2624458941461455
ENST00000371522ECHDC2chr153373539-ENST00000416070GTF2Ichr774160675+2628458941461455
ENST00000358358ECHDC2chr153373539-ENST00000324896GTF2Ichr774160675+2583417531420455
ENST00000358358ECHDC2chr153373539-ENST00000353920GTF2Ichr774160675+2583417531420455
ENST00000358358ECHDC2chr153373539-ENST00000346152GTF2Ichr774160675+2583417531420455
ENST00000358358ECHDC2chr153373539-ENST00000416070GTF2Ichr774160675+2587417531420455
ENST00000541281ECHDC2chr153373539-ENST00000324896GTF2Ichr774160675+27625963461599417
ENST00000541281ECHDC2chr153373539-ENST00000353920GTF2Ichr774160675+27625963461599417
ENST00000541281ECHDC2chr153373539-ENST00000346152GTF2Ichr774160675+27625963461599417
ENST00000541281ECHDC2chr153373539-ENST00000416070GTF2Ichr774160675+27665963461599417

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000371522ENST00000324896ECHDC2chr153373539-GTF2Ichr774160675+0.0004928330.9995072
ENST00000371522ENST00000353920ECHDC2chr153373539-GTF2Ichr774160675+0.0004928330.9995072
ENST00000371522ENST00000346152ECHDC2chr153373539-GTF2Ichr774160675+0.0004928330.9995072
ENST00000371522ENST00000416070ECHDC2chr153373539-GTF2Ichr774160675+0.0004855610.99951446
ENST00000358358ENST00000324896ECHDC2chr153373539-GTF2Ichr774160675+0.0004247360.9995753
ENST00000358358ENST00000353920ECHDC2chr153373539-GTF2Ichr774160675+0.0004247360.9995753
ENST00000358358ENST00000346152ECHDC2chr153373539-GTF2Ichr774160675+0.0004247360.9995753
ENST00000358358ENST00000416070ECHDC2chr153373539-GTF2Ichr774160675+0.0004180270.999582
ENST00000541281ENST00000324896ECHDC2chr153373539-GTF2Ichr774160675+0.0005436280.99945635
ENST00000541281ENST00000353920ECHDC2chr153373539-GTF2Ichr774160675+0.0005436280.99945635
ENST00000541281ENST00000346152ECHDC2chr153373539-GTF2Ichr774160675+0.0005436280.99945635
ENST00000541281ENST00000416070ECHDC2chr153373539-GTF2Ichr774160675+0.0005336210.99946636

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Fusion Genomic Features for ECHDC2-GTF2I


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
ECHDC2chr153373539-GTF2Ichr774160675+0.0109104810.98908955
ECHDC2chr153373539-GTF2Ichr774160675+0.0109104810.98908955

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for ECHDC2-GTF2I


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr1:53373539/chr7:74160675)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ECHDC2

Q86YB7

.
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneGTF2Ichr1:53373539chr7:74160675ENST000003248962135692_6956641252.6666666666667Compositional biasNote=Poly-Asn
TgeneGTF2Ichr1:53373539chr7:74160675ENST000003461522034692_6956431256.0Compositional biasNote=Poly-Asn
TgeneGTF2Ichr1:53373539chr7:74160675ENST000003539202034692_6956441257.0Compositional biasNote=Poly-Asn
TgeneGTF2Ichr1:53373539chr7:74160675ENST000004160701933692_6956231237.3333333333333Compositional biasNote=Poly-Asn
TgeneGTF2Ichr1:53373539chr7:74160675ENST000003248962135724_8186641252.6666666666667RepeatNote=GTF2I-like 5
TgeneGTF2Ichr1:53373539chr7:74160675ENST000003248962135859_9536641252.6666666666667RepeatNote=GTF2I-like 6
TgeneGTF2Ichr1:53373539chr7:74160675ENST000003461522034724_8186431256.0RepeatNote=GTF2I-like 5
TgeneGTF2Ichr1:53373539chr7:74160675ENST000003461522034859_9536431256.0RepeatNote=GTF2I-like 6
TgeneGTF2Ichr1:53373539chr7:74160675ENST000003539202034724_8186441257.0RepeatNote=GTF2I-like 5
TgeneGTF2Ichr1:53373539chr7:74160675ENST000003539202034859_9536441257.0RepeatNote=GTF2I-like 6
TgeneGTF2Ichr1:53373539chr7:74160675ENST000004160701933724_8186231237.3333333333333RepeatNote=GTF2I-like 5
TgeneGTF2Ichr1:53373539chr7:74160675ENST000004160701933859_9536231237.3333333333333RepeatNote=GTF2I-like 6

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneGTF2Ichr1:53373539chr7:74160675ENST000003248962135320_3276641252.6666666666667MotifNuclear localization signal
TgeneGTF2Ichr1:53373539chr7:74160675ENST000003461522034320_3276431256.0MotifNuclear localization signal
TgeneGTF2Ichr1:53373539chr7:74160675ENST000003539202034320_3276441257.0MotifNuclear localization signal
TgeneGTF2Ichr1:53373539chr7:74160675ENST000004160701933320_3276231237.3333333333333MotifNuclear localization signal
TgeneGTF2Ichr1:53373539chr7:74160675ENST000003248962135103_1976641252.6666666666667RepeatNote=GTF2I-like 1
TgeneGTF2Ichr1:53373539chr7:74160675ENST000003248962135352_4466641252.6666666666667RepeatNote=GTF2I-like 2
TgeneGTF2Ichr1:53373539chr7:74160675ENST000003248962135457_5516641252.6666666666667RepeatNote=GTF2I-like 3
TgeneGTF2Ichr1:53373539chr7:74160675ENST000003248962135562_6566641252.6666666666667RepeatNote=GTF2I-like 4
TgeneGTF2Ichr1:53373539chr7:74160675ENST000003461522034103_1976431256.0RepeatNote=GTF2I-like 1
TgeneGTF2Ichr1:53373539chr7:74160675ENST000003461522034352_4466431256.0RepeatNote=GTF2I-like 2
TgeneGTF2Ichr1:53373539chr7:74160675ENST000003461522034457_5516431256.0RepeatNote=GTF2I-like 3
TgeneGTF2Ichr1:53373539chr7:74160675ENST000003461522034562_6566431256.0RepeatNote=GTF2I-like 4
TgeneGTF2Ichr1:53373539chr7:74160675ENST000003539202034103_1976441257.0RepeatNote=GTF2I-like 1
TgeneGTF2Ichr1:53373539chr7:74160675ENST000003539202034352_4466441257.0RepeatNote=GTF2I-like 2
TgeneGTF2Ichr1:53373539chr7:74160675ENST000003539202034457_5516441257.0RepeatNote=GTF2I-like 3
TgeneGTF2Ichr1:53373539chr7:74160675ENST000003539202034562_6566441257.0RepeatNote=GTF2I-like 4
TgeneGTF2Ichr1:53373539chr7:74160675ENST000004160701933103_1976231237.3333333333333RepeatNote=GTF2I-like 1
TgeneGTF2Ichr1:53373539chr7:74160675ENST000004160701933352_4466231237.3333333333333RepeatNote=GTF2I-like 2
TgeneGTF2Ichr1:53373539chr7:74160675ENST000004160701933457_5516231237.3333333333333RepeatNote=GTF2I-like 3
TgeneGTF2Ichr1:53373539chr7:74160675ENST000004160701933562_6566231237.3333333333333RepeatNote=GTF2I-like 4


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Fusion Gene Sequence for ECHDC2-GTF2I


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>24892_24892_1_ECHDC2-GTF2I_ECHDC2_chr1_53373539_ENST00000358358_GTF2I_chr7_74160675_ENST00000324896_length(transcript)=2583nt_BP=417nt
AGCCGAGACGGTGCAGGGCCGGAGAAGCACCTTCACTCCCAGCCTGCGCCCCGATGCTGCGCGTTCTGTGCCTCCTGCGCCCCTGGAGGC
CCCTTCGGGCCCGCGGCTGCGCTTCCGACGGGGCGGCCGGGGGCTCAGAGATCCAAGTGCGCGCCCTGGCGGGTCCGGACCAAGGGATCA
CTGAGATTCTGATGAACAGACCTTCTGCCCGCAATGCCTTGGGGAATGTCTTCGTCAGTGAGCTGCTGGAAACTCTGGCCCAGCTGCGGG
AGGACCGGCAAGTGCGTGTCCTGCTCTTCAGAAGTGGAGTGAAGGGCGTGTTCTGTGCAGGTGCAGACCTGAAGGAGCGGGAACAGATGA
GTGAAGCAGAGGTGGGGGTGTTTGTCCAGCGACTCCGGGGCCTGATGAATGACATCGCTTTGCAGTCCCCCAAAAGACCACGAAGTCCTG
GGAGTAATTCAAAGGTTCCTGAAATTGAGGTCACCGTGGAAGGCCCTAATAACAACAATCCTCAAACCTCAGCTGTTCGAACCCCGACCC
AGACTAACGGTTCTAACGTTCCCTTCAAGCCACGAGGGAGAGAGTTTTCCTTTGAGGCCTGGAATGCCAAAATCACGGACCTAAAACAGA
AAGTTGAAAATCTCTTCAATGAGAAATGTGGGGAAGCTCTTGGCCTTAAACAAGCTGTGAAGGTGCCGTTCGCGTTATTTGAGTCTTTCC
CGGAAGACTTTTATGTGGAAGGCTTACCTGAGGGTGTGCCATTCCGAAGACCATCGACTTTTGGCATTCCGAGGCTGGAGAAGATACTCA
GAAACAAAGCCAAAATTAAGTTCATCATTAAAAAGCCCGAAATGTTTGAGACGGCGATTAAGGAGAGCACCTCCTCTAAGAGCCCTCCCA
GAAAAATAAATTCATCACCCAATGTTAATACTACTGCATCAGGTGTTGAAGACCTTAACATCATTCAGGTGACAATTCCAGATGATGATA
ATGAAAGACTCTCGAAAGTTGAAAAAGCTAGACAGCTAAGAGAACAAGTGAATGACCTCTTTAGTCGGAAATTTGGTGAAGCTATTGGTA
TGGGTTTTCCTGTGAAAGTTCCCTACAGGAAAATCACAATTAACCCTGGCTGTGTGGTGGTTGATGGCATGCCCCCGGGGGTGTCCTTCA
AAGCCCCCAGCTACCTGGAAATCAGCTCCATGAGAAGGATCTTAGACTCTGCCGAGTTTATCAAATTCACGGTCATTAGACCATTTCCAG
GACTTGTGATTAATAACCAGCTGGTTGATCAGAGTGAGTCAGAAGGCCCCGTGATACAAGAATCAGCTGAACCAAGCCAGTTGGAAGTTC
CAGCCACAGAAGAAATAAAAGAGACTGATGGAAGCTCTCAGATCAAGCAAGAACCAGACCCCACGTGGTAGACCTCTTCCCTCCTAGGCT
TAAAGTATCAGTGGTTGAGAAGAGCTTTTCGGACCTGTTACTACCCCAAGCTGTGTAATATACTTGTATAACAGAAATACCTTCTATACA
AACCTTTTTTTCTACTTTTAGATAGAAATGTCTACTTTTTCAGCAGTTCTGTGAATTAAAGAGCAGAGTGACTGTGGGTCTGGAATGGCT
GGTGTACTTGGGAATGTACTATCAGGATTTTACAGCAATGCTGGGAAATGACAGGGAAAATGACAGGAATGAATCTCACCAGATTTTTTA
TGTACTCAGCAGAGCCTTGAGTTACGGTGTTTATTTTCCAATCAAGTGAAGATATCTCCTACTTCTCCTACTGGAACATCTCAGCTTCTG
CAGTGAAGAAAAATTCCTGTGATAGTTCAGTTCTTTAGTTTTTCTATTTGAAAAAAAAAAATCATTTAAATGATCCTTTGTTCACGGCTC
TCCTTAATGACTGAGTGAACAGTTCCTATCTGTATATTTGACTAAACCTTTTCCTAAGCTATCTCTCATGGTTCCTATGTTTTTTTATCA
TAATTAAAAGCAAAACCATCTGGATCACCTAACAGTCAGAGGTCAGTATCTCAGCGTGTGAATTATAGAGGAAATACAGAGAGAACCTCT
TCCACTTTTACTTTTCGTCCAAATAAAATGCATGGTGTACCAGAAGTTGAAGATCGGGTTGAGGATTGGGGCTAGCTCGATGACACTAAG
GCCCCAACATCGCGGGACCTGCTGTGGCGCGGATTCTTAGGAACGCTGTTCTAGCCGGCCCCCTCTCCAGGGGTCGCCGTGGCCGGCATT
ATTTCCTAGTTCTTCTTGTAACCCTGAGGTGCCAGCGCGGGGAGTGAGGAGGGGTCAGGGGGCTAAGGATGCAACCTCTGACGTTCTGCG
CCTTCCTAGGAGAGTCTTACATGTGTTGAGATTTCACAAGCAATGCGAGTTGTAAAATACCAGCTCTACAAGAAGCTAGGCTCTGTGACG
GCATAGTTTTCAGTAGCTTTATCACAATATTCACAATGGAGAATTATATGACATGGTAGCAGAAATAGGCCCTTTTATGTGTTGCTTCTA
TTTTACCTCAAATTGTAGATATAGGGTAATCAATAAAATCCATCCATGCCTTTCACACACTAA

>24892_24892_1_ECHDC2-GTF2I_ECHDC2_chr1_53373539_ENST00000358358_GTF2I_chr7_74160675_ENST00000324896_length(amino acids)=455AA_BP=204
MLRVLCLLRPWRPLRARGCASDGAAGGSEIQVRALAGPDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVF
CAGADLKEREQMSEAEVGVFVQRLRGLMNDIALQSPKRPRSPGSNSKVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREFSF
EAWNAKITDLKQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFET
AIKESTSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGC
VVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIRPFPGLVINNQLVDQSESEGPVIQESAEPSQLEVPATEEIKETDGSSQIKQE
PDPTW

--------------------------------------------------------------
>24892_24892_2_ECHDC2-GTF2I_ECHDC2_chr1_53373539_ENST00000358358_GTF2I_chr7_74160675_ENST00000346152_length(transcript)=2583nt_BP=417nt
AGCCGAGACGGTGCAGGGCCGGAGAAGCACCTTCACTCCCAGCCTGCGCCCCGATGCTGCGCGTTCTGTGCCTCCTGCGCCCCTGGAGGC
CCCTTCGGGCCCGCGGCTGCGCTTCCGACGGGGCGGCCGGGGGCTCAGAGATCCAAGTGCGCGCCCTGGCGGGTCCGGACCAAGGGATCA
CTGAGATTCTGATGAACAGACCTTCTGCCCGCAATGCCTTGGGGAATGTCTTCGTCAGTGAGCTGCTGGAAACTCTGGCCCAGCTGCGGG
AGGACCGGCAAGTGCGTGTCCTGCTCTTCAGAAGTGGAGTGAAGGGCGTGTTCTGTGCAGGTGCAGACCTGAAGGAGCGGGAACAGATGA
GTGAAGCAGAGGTGGGGGTGTTTGTCCAGCGACTCCGGGGCCTGATGAATGACATCGCTTTGCAGTCCCCCAAAAGACCACGAAGTCCTG
GGAGTAATTCAAAGGTTCCTGAAATTGAGGTCACCGTGGAAGGCCCTAATAACAACAATCCTCAAACCTCAGCTGTTCGAACCCCGACCC
AGACTAACGGTTCTAACGTTCCCTTCAAGCCACGAGGGAGAGAGTTTTCCTTTGAGGCCTGGAATGCCAAAATCACGGACCTAAAACAGA
AAGTTGAAAATCTCTTCAATGAGAAATGTGGGGAAGCTCTTGGCCTTAAACAAGCTGTGAAGGTGCCGTTCGCGTTATTTGAGTCTTTCC
CGGAAGACTTTTATGTGGAAGGCTTACCTGAGGGTGTGCCATTCCGAAGACCATCGACTTTTGGCATTCCGAGGCTGGAGAAGATACTCA
GAAACAAAGCCAAAATTAAGTTCATCATTAAAAAGCCCGAAATGTTTGAGACGGCGATTAAGGAGAGCACCTCCTCTAAGAGCCCTCCCA
GAAAAATAAATTCATCACCCAATGTTAATACTACTGCATCAGGTGTTGAAGACCTTAACATCATTCAGGTGACAATTCCAGATGATGATA
ATGAAAGACTCTCGAAAGTTGAAAAAGCTAGACAGCTAAGAGAACAAGTGAATGACCTCTTTAGTCGGAAATTTGGTGAAGCTATTGGTA
TGGGTTTTCCTGTGAAAGTTCCCTACAGGAAAATCACAATTAACCCTGGCTGTGTGGTGGTTGATGGCATGCCCCCGGGGGTGTCCTTCA
AAGCCCCCAGCTACCTGGAAATCAGCTCCATGAGAAGGATCTTAGACTCTGCCGAGTTTATCAAATTCACGGTCATTAGACCATTTCCAG
GACTTGTGATTAATAACCAGCTGGTTGATCAGAGTGAGTCAGAAGGCCCCGTGATACAAGAATCAGCTGAACCAAGCCAGTTGGAAGTTC
CAGCCACAGAAGAAATAAAAGAGACTGATGGAAGCTCTCAGATCAAGCAAGAACCAGACCCCACGTGGTAGACCTCTTCCCTCCTAGGCT
TAAAGTATCAGTGGTTGAGAAGAGCTTTTCGGACCTGTTACTACCCCAAGCTGTGTAATATACTTGTATAACAGAAATACCTTCTATACA
AACCTTTTTTTCTACTTTTAGATAGAAATGTCTACTTTTTCAGCAGTTCTGTGAATTAAAGAGCAGAGTGACTGTGGGTCTGGAATGGCT
GGTGTACTTGGGAATGTACTATCAGGATTTTACAGCAATGCTGGGAAATGACAGGGAAAATGACAGGAATGAATCTCACCAGATTTTTTA
TGTACTCAGCAGAGCCTTGAGTTACGGTGTTTATTTTCCAATCAAGTGAAGATATCTCCTACTTCTCCTACTGGAACATCTCAGCTTCTG
CAGTGAAGAAAAATTCCTGTGATAGTTCAGTTCTTTAGTTTTTCTATTTGAAAAAAAAAAATCATTTAAATGATCCTTTGTTCACGGCTC
TCCTTAATGACTGAGTGAACAGTTCCTATCTGTATATTTGACTAAACCTTTTCCTAAGCTATCTCTCATGGTTCCTATGTTTTTTTATCA
TAATTAAAAGCAAAACCATCTGGATCACCTAACAGTCAGAGGTCAGTATCTCAGCGTGTGAATTATAGAGGAAATACAGAGAGAACCTCT
TCCACTTTTACTTTTCGTCCAAATAAAATGCATGGTGTACCAGAAGTTGAAGATCGGGTTGAGGATTGGGGCTAGCTCGATGACACTAAG
GCCCCAACATCGCGGGACCTGCTGTGGCGCGGATTCTTAGGAACGCTGTTCTAGCCGGCCCCCTCTCCAGGGGTCGCCGTGGCCGGCATT
ATTTCCTAGTTCTTCTTGTAACCCTGAGGTGCCAGCGCGGGGAGTGAGGAGGGGTCAGGGGGCTAAGGATGCAACCTCTGACGTTCTGCG
CCTTCCTAGGAGAGTCTTACATGTGTTGAGATTTCACAAGCAATGCGAGTTGTAAAATACCAGCTCTACAAGAAGCTAGGCTCTGTGACG
GCATAGTTTTCAGTAGCTTTATCACAATATTCACAATGGAGAATTATATGACATGGTAGCAGAAATAGGCCCTTTTATGTGTTGCTTCTA
TTTTACCTCAAATTGTAGATATAGGGTAATCAATAAAATCCATCCATGCCTTTCACACACTAA

>24892_24892_2_ECHDC2-GTF2I_ECHDC2_chr1_53373539_ENST00000358358_GTF2I_chr7_74160675_ENST00000346152_length(amino acids)=455AA_BP=204
MLRVLCLLRPWRPLRARGCASDGAAGGSEIQVRALAGPDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVF
CAGADLKEREQMSEAEVGVFVQRLRGLMNDIALQSPKRPRSPGSNSKVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREFSF
EAWNAKITDLKQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFET
AIKESTSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGC
VVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIRPFPGLVINNQLVDQSESEGPVIQESAEPSQLEVPATEEIKETDGSSQIKQE
PDPTW

--------------------------------------------------------------
>24892_24892_3_ECHDC2-GTF2I_ECHDC2_chr1_53373539_ENST00000358358_GTF2I_chr7_74160675_ENST00000353920_length(transcript)=2583nt_BP=417nt
AGCCGAGACGGTGCAGGGCCGGAGAAGCACCTTCACTCCCAGCCTGCGCCCCGATGCTGCGCGTTCTGTGCCTCCTGCGCCCCTGGAGGC
CCCTTCGGGCCCGCGGCTGCGCTTCCGACGGGGCGGCCGGGGGCTCAGAGATCCAAGTGCGCGCCCTGGCGGGTCCGGACCAAGGGATCA
CTGAGATTCTGATGAACAGACCTTCTGCCCGCAATGCCTTGGGGAATGTCTTCGTCAGTGAGCTGCTGGAAACTCTGGCCCAGCTGCGGG
AGGACCGGCAAGTGCGTGTCCTGCTCTTCAGAAGTGGAGTGAAGGGCGTGTTCTGTGCAGGTGCAGACCTGAAGGAGCGGGAACAGATGA
GTGAAGCAGAGGTGGGGGTGTTTGTCCAGCGACTCCGGGGCCTGATGAATGACATCGCTTTGCAGTCCCCCAAAAGACCACGAAGTCCTG
GGAGTAATTCAAAGGTTCCTGAAATTGAGGTCACCGTGGAAGGCCCTAATAACAACAATCCTCAAACCTCAGCTGTTCGAACCCCGACCC
AGACTAACGGTTCTAACGTTCCCTTCAAGCCACGAGGGAGAGAGTTTTCCTTTGAGGCCTGGAATGCCAAAATCACGGACCTAAAACAGA
AAGTTGAAAATCTCTTCAATGAGAAATGTGGGGAAGCTCTTGGCCTTAAACAAGCTGTGAAGGTGCCGTTCGCGTTATTTGAGTCTTTCC
CGGAAGACTTTTATGTGGAAGGCTTACCTGAGGGTGTGCCATTCCGAAGACCATCGACTTTTGGCATTCCGAGGCTGGAGAAGATACTCA
GAAACAAAGCCAAAATTAAGTTCATCATTAAAAAGCCCGAAATGTTTGAGACGGCGATTAAGGAGAGCACCTCCTCTAAGAGCCCTCCCA
GAAAAATAAATTCATCACCCAATGTTAATACTACTGCATCAGGTGTTGAAGACCTTAACATCATTCAGGTGACAATTCCAGATGATGATA
ATGAAAGACTCTCGAAAGTTGAAAAAGCTAGACAGCTAAGAGAACAAGTGAATGACCTCTTTAGTCGGAAATTTGGTGAAGCTATTGGTA
TGGGTTTTCCTGTGAAAGTTCCCTACAGGAAAATCACAATTAACCCTGGCTGTGTGGTGGTTGATGGCATGCCCCCGGGGGTGTCCTTCA
AAGCCCCCAGCTACCTGGAAATCAGCTCCATGAGAAGGATCTTAGACTCTGCCGAGTTTATCAAATTCACGGTCATTAGACCATTTCCAG
GACTTGTGATTAATAACCAGCTGGTTGATCAGAGTGAGTCAGAAGGCCCCGTGATACAAGAATCAGCTGAACCAAGCCAGTTGGAAGTTC
CAGCCACAGAAGAAATAAAAGAGACTGATGGAAGCTCTCAGATCAAGCAAGAACCAGACCCCACGTGGTAGACCTCTTCCCTCCTAGGCT
TAAAGTATCAGTGGTTGAGAAGAGCTTTTCGGACCTGTTACTACCCCAAGCTGTGTAATATACTTGTATAACAGAAATACCTTCTATACA
AACCTTTTTTTCTACTTTTAGATAGAAATGTCTACTTTTTCAGCAGTTCTGTGAATTAAAGAGCAGAGTGACTGTGGGTCTGGAATGGCT
GGTGTACTTGGGAATGTACTATCAGGATTTTACAGCAATGCTGGGAAATGACAGGGAAAATGACAGGAATGAATCTCACCAGATTTTTTA
TGTACTCAGCAGAGCCTTGAGTTACGGTGTTTATTTTCCAATCAAGTGAAGATATCTCCTACTTCTCCTACTGGAACATCTCAGCTTCTG
CAGTGAAGAAAAATTCCTGTGATAGTTCAGTTCTTTAGTTTTTCTATTTGAAAAAAAAAAATCATTTAAATGATCCTTTGTTCACGGCTC
TCCTTAATGACTGAGTGAACAGTTCCTATCTGTATATTTGACTAAACCTTTTCCTAAGCTATCTCTCATGGTTCCTATGTTTTTTTATCA
TAATTAAAAGCAAAACCATCTGGATCACCTAACAGTCAGAGGTCAGTATCTCAGCGTGTGAATTATAGAGGAAATACAGAGAGAACCTCT
TCCACTTTTACTTTTCGTCCAAATAAAATGCATGGTGTACCAGAAGTTGAAGATCGGGTTGAGGATTGGGGCTAGCTCGATGACACTAAG
GCCCCAACATCGCGGGACCTGCTGTGGCGCGGATTCTTAGGAACGCTGTTCTAGCCGGCCCCCTCTCCAGGGGTCGCCGTGGCCGGCATT
ATTTCCTAGTTCTTCTTGTAACCCTGAGGTGCCAGCGCGGGGAGTGAGGAGGGGTCAGGGGGCTAAGGATGCAACCTCTGACGTTCTGCG
CCTTCCTAGGAGAGTCTTACATGTGTTGAGATTTCACAAGCAATGCGAGTTGTAAAATACCAGCTCTACAAGAAGCTAGGCTCTGTGACG
GCATAGTTTTCAGTAGCTTTATCACAATATTCACAATGGAGAATTATATGACATGGTAGCAGAAATAGGCCCTTTTATGTGTTGCTTCTA
TTTTACCTCAAATTGTAGATATAGGGTAATCAATAAAATCCATCCATGCCTTTCACACACTAA

>24892_24892_3_ECHDC2-GTF2I_ECHDC2_chr1_53373539_ENST00000358358_GTF2I_chr7_74160675_ENST00000353920_length(amino acids)=455AA_BP=204
MLRVLCLLRPWRPLRARGCASDGAAGGSEIQVRALAGPDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVF
CAGADLKEREQMSEAEVGVFVQRLRGLMNDIALQSPKRPRSPGSNSKVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREFSF
EAWNAKITDLKQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFET
AIKESTSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGC
VVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIRPFPGLVINNQLVDQSESEGPVIQESAEPSQLEVPATEEIKETDGSSQIKQE
PDPTW

--------------------------------------------------------------
>24892_24892_4_ECHDC2-GTF2I_ECHDC2_chr1_53373539_ENST00000358358_GTF2I_chr7_74160675_ENST00000416070_length(transcript)=2587nt_BP=417nt
AGCCGAGACGGTGCAGGGCCGGAGAAGCACCTTCACTCCCAGCCTGCGCCCCGATGCTGCGCGTTCTGTGCCTCCTGCGCCCCTGGAGGC
CCCTTCGGGCCCGCGGCTGCGCTTCCGACGGGGCGGCCGGGGGCTCAGAGATCCAAGTGCGCGCCCTGGCGGGTCCGGACCAAGGGATCA
CTGAGATTCTGATGAACAGACCTTCTGCCCGCAATGCCTTGGGGAATGTCTTCGTCAGTGAGCTGCTGGAAACTCTGGCCCAGCTGCGGG
AGGACCGGCAAGTGCGTGTCCTGCTCTTCAGAAGTGGAGTGAAGGGCGTGTTCTGTGCAGGTGCAGACCTGAAGGAGCGGGAACAGATGA
GTGAAGCAGAGGTGGGGGTGTTTGTCCAGCGACTCCGGGGCCTGATGAATGACATCGCTTTGCAGTCCCCCAAAAGACCACGAAGTCCTG
GGAGTAATTCAAAGGTTCCTGAAATTGAGGTCACCGTGGAAGGCCCTAATAACAACAATCCTCAAACCTCAGCTGTTCGAACCCCGACCC
AGACTAACGGTTCTAACGTTCCCTTCAAGCCACGAGGGAGAGAGTTTTCCTTTGAGGCCTGGAATGCCAAAATCACGGACCTAAAACAGA
AAGTTGAAAATCTCTTCAATGAGAAATGTGGGGAAGCTCTTGGCCTTAAACAAGCTGTGAAGGTGCCGTTCGCGTTATTTGAGTCTTTCC
CGGAAGACTTTTATGTGGAAGGCTTACCTGAGGGTGTGCCATTCCGAAGACCATCGACTTTTGGCATTCCGAGGCTGGAGAAGATACTCA
GAAACAAAGCCAAAATTAAGTTCATCATTAAAAAGCCCGAAATGTTTGAGACGGCGATTAAGGAGAGCACCTCCTCTAAGAGCCCTCCCA
GAAAAATAAATTCATCACCCAATGTTAATACTACTGCATCAGGTGTTGAAGACCTTAACATCATTCAGGTGACAATTCCAGATGATGATA
ATGAAAGACTCTCGAAAGTTGAAAAAGCTAGACAGCTAAGAGAACAAGTGAATGACCTCTTTAGTCGGAAATTTGGTGAAGCTATTGGTA
TGGGTTTTCCTGTGAAAGTTCCCTACAGGAAAATCACAATTAACCCTGGCTGTGTGGTGGTTGATGGCATGCCCCCGGGGGTGTCCTTCA
AAGCCCCCAGCTACCTGGAAATCAGCTCCATGAGAAGGATCTTAGACTCTGCCGAGTTTATCAAATTCACGGTCATTAGACCATTTCCAG
GACTTGTGATTAATAACCAGCTGGTTGATCAGAGTGAGTCAGAAGGCCCCGTGATACAAGAATCAGCTGAACCAAGCCAGTTGGAAGTTC
CAGCCACAGAAGAAATAAAAGAGACTGATGGAAGCTCTCAGATCAAGCAAGAACCAGACCCCACGTGGTAGACCTCTTCCCTCCTAGGCT
TAAAGTATCAGTGGTTGAGAAGAGCTTTTCGGACCTGTTACTACCCCAAGCTGTGTAATATACTTGTATAACAGAAATACCTTCTATACA
AACCTTTTTTTCTACTTTTAGATAGAAATGTCTACTTTTTCAGCAGTTCTGTGAATTAAAGAGCAGAGTGACTGTGGGTCTGGAATGGCT
GGTGTACTTGGGAATGTACTATCAGGATTTTACAGCAATGCTGGGAAATGACAGGGAAAATGACAGGAATGAATCTCACCAGATTTTTTA
TGTACTCAGCAGAGCCTTGAGTTACGGTGTTTATTTTCCAATCAAGTGAAGATATCTCCTACTTCTCCTACTGGAACATCTCAGCTTCTG
CAGTGAAGAAAAATTCCTGTGATAGTTCAGTTCTTTAGTTTTTCTATTTGAAAAAAAAAAATCATTTAAATGATCCTTTGTTCACGGCTC
TCCTTAATGACTGAGTGAACAGTTCCTATCTGTATATTTGACTAAACCTTTTCCTAAGCTATCTCTCATGGTTCCTATGTTTTTTTATCA
TAATTAAAAGCAAAACCATCTGGATCACCTAACAGTCAGAGGTCAGTATCTCAGCGTGTGAATTATAGAGGAAATACAGAGAGAACCTCT
TCCACTTTTACTTTTCGTCCAAATAAAATGCATGGTGTACCAGAAGTTGAAGATCGGGTTGAGGATTGGGGCTAGCTCGATGACACTAAG
GCCCCAACATCGCGGGACCTGCTGTGGCGCGGATTCTTAGGAACGCTGTTCTAGCCGGCCCCCTCTCCAGGGGTCGCCGTGGCCGGCATT
ATTTCCTAGTTCTTCTTGTAACCCTGAGGTGCCAGCGCGGGGAGTGAGGAGGGGTCAGGGGGCTAAGGATGCAACCTCTGACGTTCTGCG
CCTTCCTAGGAGAGTCTTACATGTGTTGAGATTTCACAAGCAATGCGAGTTGTAAAATACCAGCTCTACAAGAAGCTAGGCTCTGTGACG
GCATAGTTTTCAGTAGCTTTATCACAATATTCACAATGGAGAATTATATGACATGGTAGCAGAAATAGGCCCTTTTATGTGTTGCTTCTA
TTTTACCTCAAATTGTAGATATAGGGTAATCAATAAAATCCATCCATGCCTTTCACACACTAAGTCA

>24892_24892_4_ECHDC2-GTF2I_ECHDC2_chr1_53373539_ENST00000358358_GTF2I_chr7_74160675_ENST00000416070_length(amino acids)=455AA_BP=204
MLRVLCLLRPWRPLRARGCASDGAAGGSEIQVRALAGPDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVF
CAGADLKEREQMSEAEVGVFVQRLRGLMNDIALQSPKRPRSPGSNSKVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREFSF
EAWNAKITDLKQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFET
AIKESTSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGC
VVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIRPFPGLVINNQLVDQSESEGPVIQESAEPSQLEVPATEEIKETDGSSQIKQE
PDPTW

--------------------------------------------------------------
>24892_24892_5_ECHDC2-GTF2I_ECHDC2_chr1_53373539_ENST00000371522_GTF2I_chr7_74160675_ENST00000324896_length(transcript)=2624nt_BP=458nt
GAAGGCTTCGCCCGACGCCGGAACTGCGAGCTCTCAGCGGGAGCCGAGACGGTGCAGGGCCGGAGAAGCACCTTCACTCCCAGCCTGCGC
CCCGATGCTGCGCGTTCTGTGCCTCCTGCGCCCCTGGAGGCCCCTTCGGGCCCGCGGCTGCGCTTCCGACGGGGCGGCCGGGGGCTCAGA
GATCCAAGTGCGCGCCCTGGCGGGTCCGGACCAAGGGATCACTGAGATTCTGATGAACAGACCTTCTGCCCGCAATGCCTTGGGGAATGT
CTTCGTCAGTGAGCTGCTGGAAACTCTGGCCCAGCTGCGGGAGGACCGGCAAGTGCGTGTCCTGCTCTTCAGAAGTGGAGTGAAGGGCGT
GTTCTGTGCAGGTGCAGACCTGAAGGAGCGGGAACAGATGAGTGAAGCAGAGGTGGGGGTGTTTGTCCAGCGACTCCGGGGCCTGATGAA
TGACATCGCTTTGCAGTCCCCCAAAAGACCACGAAGTCCTGGGAGTAATTCAAAGGTTCCTGAAATTGAGGTCACCGTGGAAGGCCCTAA
TAACAACAATCCTCAAACCTCAGCTGTTCGAACCCCGACCCAGACTAACGGTTCTAACGTTCCCTTCAAGCCACGAGGGAGAGAGTTTTC
CTTTGAGGCCTGGAATGCCAAAATCACGGACCTAAAACAGAAAGTTGAAAATCTCTTCAATGAGAAATGTGGGGAAGCTCTTGGCCTTAA
ACAAGCTGTGAAGGTGCCGTTCGCGTTATTTGAGTCTTTCCCGGAAGACTTTTATGTGGAAGGCTTACCTGAGGGTGTGCCATTCCGAAG
ACCATCGACTTTTGGCATTCCGAGGCTGGAGAAGATACTCAGAAACAAAGCCAAAATTAAGTTCATCATTAAAAAGCCCGAAATGTTTGA
GACGGCGATTAAGGAGAGCACCTCCTCTAAGAGCCCTCCCAGAAAAATAAATTCATCACCCAATGTTAATACTACTGCATCAGGTGTTGA
AGACCTTAACATCATTCAGGTGACAATTCCAGATGATGATAATGAAAGACTCTCGAAAGTTGAAAAAGCTAGACAGCTAAGAGAACAAGT
GAATGACCTCTTTAGTCGGAAATTTGGTGAAGCTATTGGTATGGGTTTTCCTGTGAAAGTTCCCTACAGGAAAATCACAATTAACCCTGG
CTGTGTGGTGGTTGATGGCATGCCCCCGGGGGTGTCCTTCAAAGCCCCCAGCTACCTGGAAATCAGCTCCATGAGAAGGATCTTAGACTC
TGCCGAGTTTATCAAATTCACGGTCATTAGACCATTTCCAGGACTTGTGATTAATAACCAGCTGGTTGATCAGAGTGAGTCAGAAGGCCC
CGTGATACAAGAATCAGCTGAACCAAGCCAGTTGGAAGTTCCAGCCACAGAAGAAATAAAAGAGACTGATGGAAGCTCTCAGATCAAGCA
AGAACCAGACCCCACGTGGTAGACCTCTTCCCTCCTAGGCTTAAAGTATCAGTGGTTGAGAAGAGCTTTTCGGACCTGTTACTACCCCAA
GCTGTGTAATATACTTGTATAACAGAAATACCTTCTATACAAACCTTTTTTTCTACTTTTAGATAGAAATGTCTACTTTTTCAGCAGTTC
TGTGAATTAAAGAGCAGAGTGACTGTGGGTCTGGAATGGCTGGTGTACTTGGGAATGTACTATCAGGATTTTACAGCAATGCTGGGAAAT
GACAGGGAAAATGACAGGAATGAATCTCACCAGATTTTTTATGTACTCAGCAGAGCCTTGAGTTACGGTGTTTATTTTCCAATCAAGTGA
AGATATCTCCTACTTCTCCTACTGGAACATCTCAGCTTCTGCAGTGAAGAAAAATTCCTGTGATAGTTCAGTTCTTTAGTTTTTCTATTT
GAAAAAAAAAAATCATTTAAATGATCCTTTGTTCACGGCTCTCCTTAATGACTGAGTGAACAGTTCCTATCTGTATATTTGACTAAACCT
TTTCCTAAGCTATCTCTCATGGTTCCTATGTTTTTTTATCATAATTAAAAGCAAAACCATCTGGATCACCTAACAGTCAGAGGTCAGTAT
CTCAGCGTGTGAATTATAGAGGAAATACAGAGAGAACCTCTTCCACTTTTACTTTTCGTCCAAATAAAATGCATGGTGTACCAGAAGTTG
AAGATCGGGTTGAGGATTGGGGCTAGCTCGATGACACTAAGGCCCCAACATCGCGGGACCTGCTGTGGCGCGGATTCTTAGGAACGCTGT
TCTAGCCGGCCCCCTCTCCAGGGGTCGCCGTGGCCGGCATTATTTCCTAGTTCTTCTTGTAACCCTGAGGTGCCAGCGCGGGGAGTGAGG
AGGGGTCAGGGGGCTAAGGATGCAACCTCTGACGTTCTGCGCCTTCCTAGGAGAGTCTTACATGTGTTGAGATTTCACAAGCAATGCGAG
TTGTAAAATACCAGCTCTACAAGAAGCTAGGCTCTGTGACGGCATAGTTTTCAGTAGCTTTATCACAATATTCACAATGGAGAATTATAT
GACATGGTAGCAGAAATAGGCCCTTTTATGTGTTGCTTCTATTTTACCTCAAATTGTAGATATAGGGTAATCAATAAAATCCATCCATGC
CTTTCACACACTAA

>24892_24892_5_ECHDC2-GTF2I_ECHDC2_chr1_53373539_ENST00000371522_GTF2I_chr7_74160675_ENST00000324896_length(amino acids)=455AA_BP=204
MLRVLCLLRPWRPLRARGCASDGAAGGSEIQVRALAGPDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVF
CAGADLKEREQMSEAEVGVFVQRLRGLMNDIALQSPKRPRSPGSNSKVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREFSF
EAWNAKITDLKQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFET
AIKESTSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGC
VVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIRPFPGLVINNQLVDQSESEGPVIQESAEPSQLEVPATEEIKETDGSSQIKQE
PDPTW

--------------------------------------------------------------
>24892_24892_6_ECHDC2-GTF2I_ECHDC2_chr1_53373539_ENST00000371522_GTF2I_chr7_74160675_ENST00000346152_length(transcript)=2624nt_BP=458nt
GAAGGCTTCGCCCGACGCCGGAACTGCGAGCTCTCAGCGGGAGCCGAGACGGTGCAGGGCCGGAGAAGCACCTTCACTCCCAGCCTGCGC
CCCGATGCTGCGCGTTCTGTGCCTCCTGCGCCCCTGGAGGCCCCTTCGGGCCCGCGGCTGCGCTTCCGACGGGGCGGCCGGGGGCTCAGA
GATCCAAGTGCGCGCCCTGGCGGGTCCGGACCAAGGGATCACTGAGATTCTGATGAACAGACCTTCTGCCCGCAATGCCTTGGGGAATGT
CTTCGTCAGTGAGCTGCTGGAAACTCTGGCCCAGCTGCGGGAGGACCGGCAAGTGCGTGTCCTGCTCTTCAGAAGTGGAGTGAAGGGCGT
GTTCTGTGCAGGTGCAGACCTGAAGGAGCGGGAACAGATGAGTGAAGCAGAGGTGGGGGTGTTTGTCCAGCGACTCCGGGGCCTGATGAA
TGACATCGCTTTGCAGTCCCCCAAAAGACCACGAAGTCCTGGGAGTAATTCAAAGGTTCCTGAAATTGAGGTCACCGTGGAAGGCCCTAA
TAACAACAATCCTCAAACCTCAGCTGTTCGAACCCCGACCCAGACTAACGGTTCTAACGTTCCCTTCAAGCCACGAGGGAGAGAGTTTTC
CTTTGAGGCCTGGAATGCCAAAATCACGGACCTAAAACAGAAAGTTGAAAATCTCTTCAATGAGAAATGTGGGGAAGCTCTTGGCCTTAA
ACAAGCTGTGAAGGTGCCGTTCGCGTTATTTGAGTCTTTCCCGGAAGACTTTTATGTGGAAGGCTTACCTGAGGGTGTGCCATTCCGAAG
ACCATCGACTTTTGGCATTCCGAGGCTGGAGAAGATACTCAGAAACAAAGCCAAAATTAAGTTCATCATTAAAAAGCCCGAAATGTTTGA
GACGGCGATTAAGGAGAGCACCTCCTCTAAGAGCCCTCCCAGAAAAATAAATTCATCACCCAATGTTAATACTACTGCATCAGGTGTTGA
AGACCTTAACATCATTCAGGTGACAATTCCAGATGATGATAATGAAAGACTCTCGAAAGTTGAAAAAGCTAGACAGCTAAGAGAACAAGT
GAATGACCTCTTTAGTCGGAAATTTGGTGAAGCTATTGGTATGGGTTTTCCTGTGAAAGTTCCCTACAGGAAAATCACAATTAACCCTGG
CTGTGTGGTGGTTGATGGCATGCCCCCGGGGGTGTCCTTCAAAGCCCCCAGCTACCTGGAAATCAGCTCCATGAGAAGGATCTTAGACTC
TGCCGAGTTTATCAAATTCACGGTCATTAGACCATTTCCAGGACTTGTGATTAATAACCAGCTGGTTGATCAGAGTGAGTCAGAAGGCCC
CGTGATACAAGAATCAGCTGAACCAAGCCAGTTGGAAGTTCCAGCCACAGAAGAAATAAAAGAGACTGATGGAAGCTCTCAGATCAAGCA
AGAACCAGACCCCACGTGGTAGACCTCTTCCCTCCTAGGCTTAAAGTATCAGTGGTTGAGAAGAGCTTTTCGGACCTGTTACTACCCCAA
GCTGTGTAATATACTTGTATAACAGAAATACCTTCTATACAAACCTTTTTTTCTACTTTTAGATAGAAATGTCTACTTTTTCAGCAGTTC
TGTGAATTAAAGAGCAGAGTGACTGTGGGTCTGGAATGGCTGGTGTACTTGGGAATGTACTATCAGGATTTTACAGCAATGCTGGGAAAT
GACAGGGAAAATGACAGGAATGAATCTCACCAGATTTTTTATGTACTCAGCAGAGCCTTGAGTTACGGTGTTTATTTTCCAATCAAGTGA
AGATATCTCCTACTTCTCCTACTGGAACATCTCAGCTTCTGCAGTGAAGAAAAATTCCTGTGATAGTTCAGTTCTTTAGTTTTTCTATTT
GAAAAAAAAAAATCATTTAAATGATCCTTTGTTCACGGCTCTCCTTAATGACTGAGTGAACAGTTCCTATCTGTATATTTGACTAAACCT
TTTCCTAAGCTATCTCTCATGGTTCCTATGTTTTTTTATCATAATTAAAAGCAAAACCATCTGGATCACCTAACAGTCAGAGGTCAGTAT
CTCAGCGTGTGAATTATAGAGGAAATACAGAGAGAACCTCTTCCACTTTTACTTTTCGTCCAAATAAAATGCATGGTGTACCAGAAGTTG
AAGATCGGGTTGAGGATTGGGGCTAGCTCGATGACACTAAGGCCCCAACATCGCGGGACCTGCTGTGGCGCGGATTCTTAGGAACGCTGT
TCTAGCCGGCCCCCTCTCCAGGGGTCGCCGTGGCCGGCATTATTTCCTAGTTCTTCTTGTAACCCTGAGGTGCCAGCGCGGGGAGTGAGG
AGGGGTCAGGGGGCTAAGGATGCAACCTCTGACGTTCTGCGCCTTCCTAGGAGAGTCTTACATGTGTTGAGATTTCACAAGCAATGCGAG
TTGTAAAATACCAGCTCTACAAGAAGCTAGGCTCTGTGACGGCATAGTTTTCAGTAGCTTTATCACAATATTCACAATGGAGAATTATAT
GACATGGTAGCAGAAATAGGCCCTTTTATGTGTTGCTTCTATTTTACCTCAAATTGTAGATATAGGGTAATCAATAAAATCCATCCATGC
CTTTCACACACTAA

>24892_24892_6_ECHDC2-GTF2I_ECHDC2_chr1_53373539_ENST00000371522_GTF2I_chr7_74160675_ENST00000346152_length(amino acids)=455AA_BP=204
MLRVLCLLRPWRPLRARGCASDGAAGGSEIQVRALAGPDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVF
CAGADLKEREQMSEAEVGVFVQRLRGLMNDIALQSPKRPRSPGSNSKVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREFSF
EAWNAKITDLKQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFET
AIKESTSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGC
VVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIRPFPGLVINNQLVDQSESEGPVIQESAEPSQLEVPATEEIKETDGSSQIKQE
PDPTW

--------------------------------------------------------------
>24892_24892_7_ECHDC2-GTF2I_ECHDC2_chr1_53373539_ENST00000371522_GTF2I_chr7_74160675_ENST00000353920_length(transcript)=2624nt_BP=458nt
GAAGGCTTCGCCCGACGCCGGAACTGCGAGCTCTCAGCGGGAGCCGAGACGGTGCAGGGCCGGAGAAGCACCTTCACTCCCAGCCTGCGC
CCCGATGCTGCGCGTTCTGTGCCTCCTGCGCCCCTGGAGGCCCCTTCGGGCCCGCGGCTGCGCTTCCGACGGGGCGGCCGGGGGCTCAGA
GATCCAAGTGCGCGCCCTGGCGGGTCCGGACCAAGGGATCACTGAGATTCTGATGAACAGACCTTCTGCCCGCAATGCCTTGGGGAATGT
CTTCGTCAGTGAGCTGCTGGAAACTCTGGCCCAGCTGCGGGAGGACCGGCAAGTGCGTGTCCTGCTCTTCAGAAGTGGAGTGAAGGGCGT
GTTCTGTGCAGGTGCAGACCTGAAGGAGCGGGAACAGATGAGTGAAGCAGAGGTGGGGGTGTTTGTCCAGCGACTCCGGGGCCTGATGAA
TGACATCGCTTTGCAGTCCCCCAAAAGACCACGAAGTCCTGGGAGTAATTCAAAGGTTCCTGAAATTGAGGTCACCGTGGAAGGCCCTAA
TAACAACAATCCTCAAACCTCAGCTGTTCGAACCCCGACCCAGACTAACGGTTCTAACGTTCCCTTCAAGCCACGAGGGAGAGAGTTTTC
CTTTGAGGCCTGGAATGCCAAAATCACGGACCTAAAACAGAAAGTTGAAAATCTCTTCAATGAGAAATGTGGGGAAGCTCTTGGCCTTAA
ACAAGCTGTGAAGGTGCCGTTCGCGTTATTTGAGTCTTTCCCGGAAGACTTTTATGTGGAAGGCTTACCTGAGGGTGTGCCATTCCGAAG
ACCATCGACTTTTGGCATTCCGAGGCTGGAGAAGATACTCAGAAACAAAGCCAAAATTAAGTTCATCATTAAAAAGCCCGAAATGTTTGA
GACGGCGATTAAGGAGAGCACCTCCTCTAAGAGCCCTCCCAGAAAAATAAATTCATCACCCAATGTTAATACTACTGCATCAGGTGTTGA
AGACCTTAACATCATTCAGGTGACAATTCCAGATGATGATAATGAAAGACTCTCGAAAGTTGAAAAAGCTAGACAGCTAAGAGAACAAGT
GAATGACCTCTTTAGTCGGAAATTTGGTGAAGCTATTGGTATGGGTTTTCCTGTGAAAGTTCCCTACAGGAAAATCACAATTAACCCTGG
CTGTGTGGTGGTTGATGGCATGCCCCCGGGGGTGTCCTTCAAAGCCCCCAGCTACCTGGAAATCAGCTCCATGAGAAGGATCTTAGACTC
TGCCGAGTTTATCAAATTCACGGTCATTAGACCATTTCCAGGACTTGTGATTAATAACCAGCTGGTTGATCAGAGTGAGTCAGAAGGCCC
CGTGATACAAGAATCAGCTGAACCAAGCCAGTTGGAAGTTCCAGCCACAGAAGAAATAAAAGAGACTGATGGAAGCTCTCAGATCAAGCA
AGAACCAGACCCCACGTGGTAGACCTCTTCCCTCCTAGGCTTAAAGTATCAGTGGTTGAGAAGAGCTTTTCGGACCTGTTACTACCCCAA
GCTGTGTAATATACTTGTATAACAGAAATACCTTCTATACAAACCTTTTTTTCTACTTTTAGATAGAAATGTCTACTTTTTCAGCAGTTC
TGTGAATTAAAGAGCAGAGTGACTGTGGGTCTGGAATGGCTGGTGTACTTGGGAATGTACTATCAGGATTTTACAGCAATGCTGGGAAAT
GACAGGGAAAATGACAGGAATGAATCTCACCAGATTTTTTATGTACTCAGCAGAGCCTTGAGTTACGGTGTTTATTTTCCAATCAAGTGA
AGATATCTCCTACTTCTCCTACTGGAACATCTCAGCTTCTGCAGTGAAGAAAAATTCCTGTGATAGTTCAGTTCTTTAGTTTTTCTATTT
GAAAAAAAAAAATCATTTAAATGATCCTTTGTTCACGGCTCTCCTTAATGACTGAGTGAACAGTTCCTATCTGTATATTTGACTAAACCT
TTTCCTAAGCTATCTCTCATGGTTCCTATGTTTTTTTATCATAATTAAAAGCAAAACCATCTGGATCACCTAACAGTCAGAGGTCAGTAT
CTCAGCGTGTGAATTATAGAGGAAATACAGAGAGAACCTCTTCCACTTTTACTTTTCGTCCAAATAAAATGCATGGTGTACCAGAAGTTG
AAGATCGGGTTGAGGATTGGGGCTAGCTCGATGACACTAAGGCCCCAACATCGCGGGACCTGCTGTGGCGCGGATTCTTAGGAACGCTGT
TCTAGCCGGCCCCCTCTCCAGGGGTCGCCGTGGCCGGCATTATTTCCTAGTTCTTCTTGTAACCCTGAGGTGCCAGCGCGGGGAGTGAGG
AGGGGTCAGGGGGCTAAGGATGCAACCTCTGACGTTCTGCGCCTTCCTAGGAGAGTCTTACATGTGTTGAGATTTCACAAGCAATGCGAG
TTGTAAAATACCAGCTCTACAAGAAGCTAGGCTCTGTGACGGCATAGTTTTCAGTAGCTTTATCACAATATTCACAATGGAGAATTATAT
GACATGGTAGCAGAAATAGGCCCTTTTATGTGTTGCTTCTATTTTACCTCAAATTGTAGATATAGGGTAATCAATAAAATCCATCCATGC
CTTTCACACACTAA

>24892_24892_7_ECHDC2-GTF2I_ECHDC2_chr1_53373539_ENST00000371522_GTF2I_chr7_74160675_ENST00000353920_length(amino acids)=455AA_BP=204
MLRVLCLLRPWRPLRARGCASDGAAGGSEIQVRALAGPDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVF
CAGADLKEREQMSEAEVGVFVQRLRGLMNDIALQSPKRPRSPGSNSKVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREFSF
EAWNAKITDLKQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFET
AIKESTSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGC
VVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIRPFPGLVINNQLVDQSESEGPVIQESAEPSQLEVPATEEIKETDGSSQIKQE
PDPTW

--------------------------------------------------------------
>24892_24892_8_ECHDC2-GTF2I_ECHDC2_chr1_53373539_ENST00000371522_GTF2I_chr7_74160675_ENST00000416070_length(transcript)=2628nt_BP=458nt
GAAGGCTTCGCCCGACGCCGGAACTGCGAGCTCTCAGCGGGAGCCGAGACGGTGCAGGGCCGGAGAAGCACCTTCACTCCCAGCCTGCGC
CCCGATGCTGCGCGTTCTGTGCCTCCTGCGCCCCTGGAGGCCCCTTCGGGCCCGCGGCTGCGCTTCCGACGGGGCGGCCGGGGGCTCAGA
GATCCAAGTGCGCGCCCTGGCGGGTCCGGACCAAGGGATCACTGAGATTCTGATGAACAGACCTTCTGCCCGCAATGCCTTGGGGAATGT
CTTCGTCAGTGAGCTGCTGGAAACTCTGGCCCAGCTGCGGGAGGACCGGCAAGTGCGTGTCCTGCTCTTCAGAAGTGGAGTGAAGGGCGT
GTTCTGTGCAGGTGCAGACCTGAAGGAGCGGGAACAGATGAGTGAAGCAGAGGTGGGGGTGTTTGTCCAGCGACTCCGGGGCCTGATGAA
TGACATCGCTTTGCAGTCCCCCAAAAGACCACGAAGTCCTGGGAGTAATTCAAAGGTTCCTGAAATTGAGGTCACCGTGGAAGGCCCTAA
TAACAACAATCCTCAAACCTCAGCTGTTCGAACCCCGACCCAGACTAACGGTTCTAACGTTCCCTTCAAGCCACGAGGGAGAGAGTTTTC
CTTTGAGGCCTGGAATGCCAAAATCACGGACCTAAAACAGAAAGTTGAAAATCTCTTCAATGAGAAATGTGGGGAAGCTCTTGGCCTTAA
ACAAGCTGTGAAGGTGCCGTTCGCGTTATTTGAGTCTTTCCCGGAAGACTTTTATGTGGAAGGCTTACCTGAGGGTGTGCCATTCCGAAG
ACCATCGACTTTTGGCATTCCGAGGCTGGAGAAGATACTCAGAAACAAAGCCAAAATTAAGTTCATCATTAAAAAGCCCGAAATGTTTGA
GACGGCGATTAAGGAGAGCACCTCCTCTAAGAGCCCTCCCAGAAAAATAAATTCATCACCCAATGTTAATACTACTGCATCAGGTGTTGA
AGACCTTAACATCATTCAGGTGACAATTCCAGATGATGATAATGAAAGACTCTCGAAAGTTGAAAAAGCTAGACAGCTAAGAGAACAAGT
GAATGACCTCTTTAGTCGGAAATTTGGTGAAGCTATTGGTATGGGTTTTCCTGTGAAAGTTCCCTACAGGAAAATCACAATTAACCCTGG
CTGTGTGGTGGTTGATGGCATGCCCCCGGGGGTGTCCTTCAAAGCCCCCAGCTACCTGGAAATCAGCTCCATGAGAAGGATCTTAGACTC
TGCCGAGTTTATCAAATTCACGGTCATTAGACCATTTCCAGGACTTGTGATTAATAACCAGCTGGTTGATCAGAGTGAGTCAGAAGGCCC
CGTGATACAAGAATCAGCTGAACCAAGCCAGTTGGAAGTTCCAGCCACAGAAGAAATAAAAGAGACTGATGGAAGCTCTCAGATCAAGCA
AGAACCAGACCCCACGTGGTAGACCTCTTCCCTCCTAGGCTTAAAGTATCAGTGGTTGAGAAGAGCTTTTCGGACCTGTTACTACCCCAA
GCTGTGTAATATACTTGTATAACAGAAATACCTTCTATACAAACCTTTTTTTCTACTTTTAGATAGAAATGTCTACTTTTTCAGCAGTTC
TGTGAATTAAAGAGCAGAGTGACTGTGGGTCTGGAATGGCTGGTGTACTTGGGAATGTACTATCAGGATTTTACAGCAATGCTGGGAAAT
GACAGGGAAAATGACAGGAATGAATCTCACCAGATTTTTTATGTACTCAGCAGAGCCTTGAGTTACGGTGTTTATTTTCCAATCAAGTGA
AGATATCTCCTACTTCTCCTACTGGAACATCTCAGCTTCTGCAGTGAAGAAAAATTCCTGTGATAGTTCAGTTCTTTAGTTTTTCTATTT
GAAAAAAAAAAATCATTTAAATGATCCTTTGTTCACGGCTCTCCTTAATGACTGAGTGAACAGTTCCTATCTGTATATTTGACTAAACCT
TTTCCTAAGCTATCTCTCATGGTTCCTATGTTTTTTTATCATAATTAAAAGCAAAACCATCTGGATCACCTAACAGTCAGAGGTCAGTAT
CTCAGCGTGTGAATTATAGAGGAAATACAGAGAGAACCTCTTCCACTTTTACTTTTCGTCCAAATAAAATGCATGGTGTACCAGAAGTTG
AAGATCGGGTTGAGGATTGGGGCTAGCTCGATGACACTAAGGCCCCAACATCGCGGGACCTGCTGTGGCGCGGATTCTTAGGAACGCTGT
TCTAGCCGGCCCCCTCTCCAGGGGTCGCCGTGGCCGGCATTATTTCCTAGTTCTTCTTGTAACCCTGAGGTGCCAGCGCGGGGAGTGAGG
AGGGGTCAGGGGGCTAAGGATGCAACCTCTGACGTTCTGCGCCTTCCTAGGAGAGTCTTACATGTGTTGAGATTTCACAAGCAATGCGAG
TTGTAAAATACCAGCTCTACAAGAAGCTAGGCTCTGTGACGGCATAGTTTTCAGTAGCTTTATCACAATATTCACAATGGAGAATTATAT
GACATGGTAGCAGAAATAGGCCCTTTTATGTGTTGCTTCTATTTTACCTCAAATTGTAGATATAGGGTAATCAATAAAATCCATCCATGC
CTTTCACACACTAAGTCA

>24892_24892_8_ECHDC2-GTF2I_ECHDC2_chr1_53373539_ENST00000371522_GTF2I_chr7_74160675_ENST00000416070_length(amino acids)=455AA_BP=204
MLRVLCLLRPWRPLRARGCASDGAAGGSEIQVRALAGPDQGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVF
CAGADLKEREQMSEAEVGVFVQRLRGLMNDIALQSPKRPRSPGSNSKVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREFSF
EAWNAKITDLKQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFET
AIKESTSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGC
VVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIRPFPGLVINNQLVDQSESEGPVIQESAEPSQLEVPATEEIKETDGSSQIKQE
PDPTW

--------------------------------------------------------------
>24892_24892_9_ECHDC2-GTF2I_ECHDC2_chr1_53373539_ENST00000541281_GTF2I_chr7_74160675_ENST00000324896_length(transcript)=2762nt_BP=596nt
AGAAGCACCTTCACTCCCAGCCTGCGCCCCGATGCTGCGCGTTCTGTGCCTCCTGCGCCCCTGGAGGCCCCTTCGGGCCCGCGGCTGCGC
TTCCGACGGGGCGGCCGGGGGCTCAGAGATCCAAGTGCGCGCCCTGGCGGGTCCGGACCAAGGCTGTAGGTTCCATGAGGACAGGCCTTG
AGTCTGTCCTGGTCTCTGGAATCACGGTGTCTAGTAGAGGCCAGCACACAGCAAATATATAAATGTACAAATGAGTGAATGAAGAGAATC
TGATTGGCCTTAAGGAACTTACGCACTTAAAATAATTGGGCAGAAGAGAAGCAGTGAAGGAGTGCAGAGGCATCACCTGAAAGGGATCAC
TGAGATTCTGATGAACAGACCTTCTGCCCGCAATGCCTTGGGGAATGTCTTCGTCAGTGAGCTGCTGGAAACTCTGGCCCAGCTGCGGGA
GGACCGGCAAGTGCGTGTCCTGCTCTTCAGAAGTGGAGTGAAGGGCGTGTTCTGTGCAGGTGCAGACCTGAAGGAGCGGGAACAGATGAG
TGAAGCAGAGGTGGGGGTGTTTGTCCAGCGACTCCGGGGCCTGATGAATGACATCGCTTTGCAGTCCCCCAAAAGACCACGAAGTCCTGG
GAGTAATTCAAAGGTTCCTGAAATTGAGGTCACCGTGGAAGGCCCTAATAACAACAATCCTCAAACCTCAGCTGTTCGAACCCCGACCCA
GACTAACGGTTCTAACGTTCCCTTCAAGCCACGAGGGAGAGAGTTTTCCTTTGAGGCCTGGAATGCCAAAATCACGGACCTAAAACAGAA
AGTTGAAAATCTCTTCAATGAGAAATGTGGGGAAGCTCTTGGCCTTAAACAAGCTGTGAAGGTGCCGTTCGCGTTATTTGAGTCTTTCCC
GGAAGACTTTTATGTGGAAGGCTTACCTGAGGGTGTGCCATTCCGAAGACCATCGACTTTTGGCATTCCGAGGCTGGAGAAGATACTCAG
AAACAAAGCCAAAATTAAGTTCATCATTAAAAAGCCCGAAATGTTTGAGACGGCGATTAAGGAGAGCACCTCCTCTAAGAGCCCTCCCAG
AAAAATAAATTCATCACCCAATGTTAATACTACTGCATCAGGTGTTGAAGACCTTAACATCATTCAGGTGACAATTCCAGATGATGATAA
TGAAAGACTCTCGAAAGTTGAAAAAGCTAGACAGCTAAGAGAACAAGTGAATGACCTCTTTAGTCGGAAATTTGGTGAAGCTATTGGTAT
GGGTTTTCCTGTGAAAGTTCCCTACAGGAAAATCACAATTAACCCTGGCTGTGTGGTGGTTGATGGCATGCCCCCGGGGGTGTCCTTCAA
AGCCCCCAGCTACCTGGAAATCAGCTCCATGAGAAGGATCTTAGACTCTGCCGAGTTTATCAAATTCACGGTCATTAGACCATTTCCAGG
ACTTGTGATTAATAACCAGCTGGTTGATCAGAGTGAGTCAGAAGGCCCCGTGATACAAGAATCAGCTGAACCAAGCCAGTTGGAAGTTCC
AGCCACAGAAGAAATAAAAGAGACTGATGGAAGCTCTCAGATCAAGCAAGAACCAGACCCCACGTGGTAGACCTCTTCCCTCCTAGGCTT
AAAGTATCAGTGGTTGAGAAGAGCTTTTCGGACCTGTTACTACCCCAAGCTGTGTAATATACTTGTATAACAGAAATACCTTCTATACAA
ACCTTTTTTTCTACTTTTAGATAGAAATGTCTACTTTTTCAGCAGTTCTGTGAATTAAAGAGCAGAGTGACTGTGGGTCTGGAATGGCTG
GTGTACTTGGGAATGTACTATCAGGATTTTACAGCAATGCTGGGAAATGACAGGGAAAATGACAGGAATGAATCTCACCAGATTTTTTAT
GTACTCAGCAGAGCCTTGAGTTACGGTGTTTATTTTCCAATCAAGTGAAGATATCTCCTACTTCTCCTACTGGAACATCTCAGCTTCTGC
AGTGAAGAAAAATTCCTGTGATAGTTCAGTTCTTTAGTTTTTCTATTTGAAAAAAAAAAATCATTTAAATGATCCTTTGTTCACGGCTCT
CCTTAATGACTGAGTGAACAGTTCCTATCTGTATATTTGACTAAACCTTTTCCTAAGCTATCTCTCATGGTTCCTATGTTTTTTTATCAT
AATTAAAAGCAAAACCATCTGGATCACCTAACAGTCAGAGGTCAGTATCTCAGCGTGTGAATTATAGAGGAAATACAGAGAGAACCTCTT
CCACTTTTACTTTTCGTCCAAATAAAATGCATGGTGTACCAGAAGTTGAAGATCGGGTTGAGGATTGGGGCTAGCTCGATGACACTAAGG
CCCCAACATCGCGGGACCTGCTGTGGCGCGGATTCTTAGGAACGCTGTTCTAGCCGGCCCCCTCTCCAGGGGTCGCCGTGGCCGGCATTA
TTTCCTAGTTCTTCTTGTAACCCTGAGGTGCCAGCGCGGGGAGTGAGGAGGGGTCAGGGGGCTAAGGATGCAACCTCTGACGTTCTGCGC
CTTCCTAGGAGAGTCTTACATGTGTTGAGATTTCACAAGCAATGCGAGTTGTAAAATACCAGCTCTACAAGAAGCTAGGCTCTGTGACGG
CATAGTTTTCAGTAGCTTTATCACAATATTCACAATGGAGAATTATATGACATGGTAGCAGAAATAGGCCCTTTTATGTGTTGCTTCTAT
TTTACCTCAAATTGTAGATATAGGGTAATCAATAAAATCCATCCATGCCTTTCACACACTAA

>24892_24892_9_ECHDC2-GTF2I_ECHDC2_chr1_53373539_ENST00000541281_GTF2I_chr7_74160675_ENST00000324896_length(amino acids)=417AA_BP=166
MKGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQMSEAEVGVFVQRLRGLMNDIALQSPKR
PRSPGSNSKVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREFSFEAWNAKITDLKQKVENLFNEKCGEALGLKQAVKVPFAL
FESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTASGVEDLNIIQVTI
PDDDNERLSKVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVI
RPFPGLVINNQLVDQSESEGPVIQESAEPSQLEVPATEEIKETDGSSQIKQEPDPTW

--------------------------------------------------------------
>24892_24892_10_ECHDC2-GTF2I_ECHDC2_chr1_53373539_ENST00000541281_GTF2I_chr7_74160675_ENST00000346152_length(transcript)=2762nt_BP=596nt
AGAAGCACCTTCACTCCCAGCCTGCGCCCCGATGCTGCGCGTTCTGTGCCTCCTGCGCCCCTGGAGGCCCCTTCGGGCCCGCGGCTGCGC
TTCCGACGGGGCGGCCGGGGGCTCAGAGATCCAAGTGCGCGCCCTGGCGGGTCCGGACCAAGGCTGTAGGTTCCATGAGGACAGGCCTTG
AGTCTGTCCTGGTCTCTGGAATCACGGTGTCTAGTAGAGGCCAGCACACAGCAAATATATAAATGTACAAATGAGTGAATGAAGAGAATC
TGATTGGCCTTAAGGAACTTACGCACTTAAAATAATTGGGCAGAAGAGAAGCAGTGAAGGAGTGCAGAGGCATCACCTGAAAGGGATCAC
TGAGATTCTGATGAACAGACCTTCTGCCCGCAATGCCTTGGGGAATGTCTTCGTCAGTGAGCTGCTGGAAACTCTGGCCCAGCTGCGGGA
GGACCGGCAAGTGCGTGTCCTGCTCTTCAGAAGTGGAGTGAAGGGCGTGTTCTGTGCAGGTGCAGACCTGAAGGAGCGGGAACAGATGAG
TGAAGCAGAGGTGGGGGTGTTTGTCCAGCGACTCCGGGGCCTGATGAATGACATCGCTTTGCAGTCCCCCAAAAGACCACGAAGTCCTGG
GAGTAATTCAAAGGTTCCTGAAATTGAGGTCACCGTGGAAGGCCCTAATAACAACAATCCTCAAACCTCAGCTGTTCGAACCCCGACCCA
GACTAACGGTTCTAACGTTCCCTTCAAGCCACGAGGGAGAGAGTTTTCCTTTGAGGCCTGGAATGCCAAAATCACGGACCTAAAACAGAA
AGTTGAAAATCTCTTCAATGAGAAATGTGGGGAAGCTCTTGGCCTTAAACAAGCTGTGAAGGTGCCGTTCGCGTTATTTGAGTCTTTCCC
GGAAGACTTTTATGTGGAAGGCTTACCTGAGGGTGTGCCATTCCGAAGACCATCGACTTTTGGCATTCCGAGGCTGGAGAAGATACTCAG
AAACAAAGCCAAAATTAAGTTCATCATTAAAAAGCCCGAAATGTTTGAGACGGCGATTAAGGAGAGCACCTCCTCTAAGAGCCCTCCCAG
AAAAATAAATTCATCACCCAATGTTAATACTACTGCATCAGGTGTTGAAGACCTTAACATCATTCAGGTGACAATTCCAGATGATGATAA
TGAAAGACTCTCGAAAGTTGAAAAAGCTAGACAGCTAAGAGAACAAGTGAATGACCTCTTTAGTCGGAAATTTGGTGAAGCTATTGGTAT
GGGTTTTCCTGTGAAAGTTCCCTACAGGAAAATCACAATTAACCCTGGCTGTGTGGTGGTTGATGGCATGCCCCCGGGGGTGTCCTTCAA
AGCCCCCAGCTACCTGGAAATCAGCTCCATGAGAAGGATCTTAGACTCTGCCGAGTTTATCAAATTCACGGTCATTAGACCATTTCCAGG
ACTTGTGATTAATAACCAGCTGGTTGATCAGAGTGAGTCAGAAGGCCCCGTGATACAAGAATCAGCTGAACCAAGCCAGTTGGAAGTTCC
AGCCACAGAAGAAATAAAAGAGACTGATGGAAGCTCTCAGATCAAGCAAGAACCAGACCCCACGTGGTAGACCTCTTCCCTCCTAGGCTT
AAAGTATCAGTGGTTGAGAAGAGCTTTTCGGACCTGTTACTACCCCAAGCTGTGTAATATACTTGTATAACAGAAATACCTTCTATACAA
ACCTTTTTTTCTACTTTTAGATAGAAATGTCTACTTTTTCAGCAGTTCTGTGAATTAAAGAGCAGAGTGACTGTGGGTCTGGAATGGCTG
GTGTACTTGGGAATGTACTATCAGGATTTTACAGCAATGCTGGGAAATGACAGGGAAAATGACAGGAATGAATCTCACCAGATTTTTTAT
GTACTCAGCAGAGCCTTGAGTTACGGTGTTTATTTTCCAATCAAGTGAAGATATCTCCTACTTCTCCTACTGGAACATCTCAGCTTCTGC
AGTGAAGAAAAATTCCTGTGATAGTTCAGTTCTTTAGTTTTTCTATTTGAAAAAAAAAAATCATTTAAATGATCCTTTGTTCACGGCTCT
CCTTAATGACTGAGTGAACAGTTCCTATCTGTATATTTGACTAAACCTTTTCCTAAGCTATCTCTCATGGTTCCTATGTTTTTTTATCAT
AATTAAAAGCAAAACCATCTGGATCACCTAACAGTCAGAGGTCAGTATCTCAGCGTGTGAATTATAGAGGAAATACAGAGAGAACCTCTT
CCACTTTTACTTTTCGTCCAAATAAAATGCATGGTGTACCAGAAGTTGAAGATCGGGTTGAGGATTGGGGCTAGCTCGATGACACTAAGG
CCCCAACATCGCGGGACCTGCTGTGGCGCGGATTCTTAGGAACGCTGTTCTAGCCGGCCCCCTCTCCAGGGGTCGCCGTGGCCGGCATTA
TTTCCTAGTTCTTCTTGTAACCCTGAGGTGCCAGCGCGGGGAGTGAGGAGGGGTCAGGGGGCTAAGGATGCAACCTCTGACGTTCTGCGC
CTTCCTAGGAGAGTCTTACATGTGTTGAGATTTCACAAGCAATGCGAGTTGTAAAATACCAGCTCTACAAGAAGCTAGGCTCTGTGACGG
CATAGTTTTCAGTAGCTTTATCACAATATTCACAATGGAGAATTATATGACATGGTAGCAGAAATAGGCCCTTTTATGTGTTGCTTCTAT
TTTACCTCAAATTGTAGATATAGGGTAATCAATAAAATCCATCCATGCCTTTCACACACTAA

>24892_24892_10_ECHDC2-GTF2I_ECHDC2_chr1_53373539_ENST00000541281_GTF2I_chr7_74160675_ENST00000346152_length(amino acids)=417AA_BP=166
MKGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQMSEAEVGVFVQRLRGLMNDIALQSPKR
PRSPGSNSKVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREFSFEAWNAKITDLKQKVENLFNEKCGEALGLKQAVKVPFAL
FESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTASGVEDLNIIQVTI
PDDDNERLSKVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVI
RPFPGLVINNQLVDQSESEGPVIQESAEPSQLEVPATEEIKETDGSSQIKQEPDPTW

--------------------------------------------------------------
>24892_24892_11_ECHDC2-GTF2I_ECHDC2_chr1_53373539_ENST00000541281_GTF2I_chr7_74160675_ENST00000353920_length(transcript)=2762nt_BP=596nt
AGAAGCACCTTCACTCCCAGCCTGCGCCCCGATGCTGCGCGTTCTGTGCCTCCTGCGCCCCTGGAGGCCCCTTCGGGCCCGCGGCTGCGC
TTCCGACGGGGCGGCCGGGGGCTCAGAGATCCAAGTGCGCGCCCTGGCGGGTCCGGACCAAGGCTGTAGGTTCCATGAGGACAGGCCTTG
AGTCTGTCCTGGTCTCTGGAATCACGGTGTCTAGTAGAGGCCAGCACACAGCAAATATATAAATGTACAAATGAGTGAATGAAGAGAATC
TGATTGGCCTTAAGGAACTTACGCACTTAAAATAATTGGGCAGAAGAGAAGCAGTGAAGGAGTGCAGAGGCATCACCTGAAAGGGATCAC
TGAGATTCTGATGAACAGACCTTCTGCCCGCAATGCCTTGGGGAATGTCTTCGTCAGTGAGCTGCTGGAAACTCTGGCCCAGCTGCGGGA
GGACCGGCAAGTGCGTGTCCTGCTCTTCAGAAGTGGAGTGAAGGGCGTGTTCTGTGCAGGTGCAGACCTGAAGGAGCGGGAACAGATGAG
TGAAGCAGAGGTGGGGGTGTTTGTCCAGCGACTCCGGGGCCTGATGAATGACATCGCTTTGCAGTCCCCCAAAAGACCACGAAGTCCTGG
GAGTAATTCAAAGGTTCCTGAAATTGAGGTCACCGTGGAAGGCCCTAATAACAACAATCCTCAAACCTCAGCTGTTCGAACCCCGACCCA
GACTAACGGTTCTAACGTTCCCTTCAAGCCACGAGGGAGAGAGTTTTCCTTTGAGGCCTGGAATGCCAAAATCACGGACCTAAAACAGAA
AGTTGAAAATCTCTTCAATGAGAAATGTGGGGAAGCTCTTGGCCTTAAACAAGCTGTGAAGGTGCCGTTCGCGTTATTTGAGTCTTTCCC
GGAAGACTTTTATGTGGAAGGCTTACCTGAGGGTGTGCCATTCCGAAGACCATCGACTTTTGGCATTCCGAGGCTGGAGAAGATACTCAG
AAACAAAGCCAAAATTAAGTTCATCATTAAAAAGCCCGAAATGTTTGAGACGGCGATTAAGGAGAGCACCTCCTCTAAGAGCCCTCCCAG
AAAAATAAATTCATCACCCAATGTTAATACTACTGCATCAGGTGTTGAAGACCTTAACATCATTCAGGTGACAATTCCAGATGATGATAA
TGAAAGACTCTCGAAAGTTGAAAAAGCTAGACAGCTAAGAGAACAAGTGAATGACCTCTTTAGTCGGAAATTTGGTGAAGCTATTGGTAT
GGGTTTTCCTGTGAAAGTTCCCTACAGGAAAATCACAATTAACCCTGGCTGTGTGGTGGTTGATGGCATGCCCCCGGGGGTGTCCTTCAA
AGCCCCCAGCTACCTGGAAATCAGCTCCATGAGAAGGATCTTAGACTCTGCCGAGTTTATCAAATTCACGGTCATTAGACCATTTCCAGG
ACTTGTGATTAATAACCAGCTGGTTGATCAGAGTGAGTCAGAAGGCCCCGTGATACAAGAATCAGCTGAACCAAGCCAGTTGGAAGTTCC
AGCCACAGAAGAAATAAAAGAGACTGATGGAAGCTCTCAGATCAAGCAAGAACCAGACCCCACGTGGTAGACCTCTTCCCTCCTAGGCTT
AAAGTATCAGTGGTTGAGAAGAGCTTTTCGGACCTGTTACTACCCCAAGCTGTGTAATATACTTGTATAACAGAAATACCTTCTATACAA
ACCTTTTTTTCTACTTTTAGATAGAAATGTCTACTTTTTCAGCAGTTCTGTGAATTAAAGAGCAGAGTGACTGTGGGTCTGGAATGGCTG
GTGTACTTGGGAATGTACTATCAGGATTTTACAGCAATGCTGGGAAATGACAGGGAAAATGACAGGAATGAATCTCACCAGATTTTTTAT
GTACTCAGCAGAGCCTTGAGTTACGGTGTTTATTTTCCAATCAAGTGAAGATATCTCCTACTTCTCCTACTGGAACATCTCAGCTTCTGC
AGTGAAGAAAAATTCCTGTGATAGTTCAGTTCTTTAGTTTTTCTATTTGAAAAAAAAAAATCATTTAAATGATCCTTTGTTCACGGCTCT
CCTTAATGACTGAGTGAACAGTTCCTATCTGTATATTTGACTAAACCTTTTCCTAAGCTATCTCTCATGGTTCCTATGTTTTTTTATCAT
AATTAAAAGCAAAACCATCTGGATCACCTAACAGTCAGAGGTCAGTATCTCAGCGTGTGAATTATAGAGGAAATACAGAGAGAACCTCTT
CCACTTTTACTTTTCGTCCAAATAAAATGCATGGTGTACCAGAAGTTGAAGATCGGGTTGAGGATTGGGGCTAGCTCGATGACACTAAGG
CCCCAACATCGCGGGACCTGCTGTGGCGCGGATTCTTAGGAACGCTGTTCTAGCCGGCCCCCTCTCCAGGGGTCGCCGTGGCCGGCATTA
TTTCCTAGTTCTTCTTGTAACCCTGAGGTGCCAGCGCGGGGAGTGAGGAGGGGTCAGGGGGCTAAGGATGCAACCTCTGACGTTCTGCGC
CTTCCTAGGAGAGTCTTACATGTGTTGAGATTTCACAAGCAATGCGAGTTGTAAAATACCAGCTCTACAAGAAGCTAGGCTCTGTGACGG
CATAGTTTTCAGTAGCTTTATCACAATATTCACAATGGAGAATTATATGACATGGTAGCAGAAATAGGCCCTTTTATGTGTTGCTTCTAT
TTTACCTCAAATTGTAGATATAGGGTAATCAATAAAATCCATCCATGCCTTTCACACACTAA

>24892_24892_11_ECHDC2-GTF2I_ECHDC2_chr1_53373539_ENST00000541281_GTF2I_chr7_74160675_ENST00000353920_length(amino acids)=417AA_BP=166
MKGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQMSEAEVGVFVQRLRGLMNDIALQSPKR
PRSPGSNSKVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREFSFEAWNAKITDLKQKVENLFNEKCGEALGLKQAVKVPFAL
FESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTASGVEDLNIIQVTI
PDDDNERLSKVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVI
RPFPGLVINNQLVDQSESEGPVIQESAEPSQLEVPATEEIKETDGSSQIKQEPDPTW

--------------------------------------------------------------
>24892_24892_12_ECHDC2-GTF2I_ECHDC2_chr1_53373539_ENST00000541281_GTF2I_chr7_74160675_ENST00000416070_length(transcript)=2766nt_BP=596nt
AGAAGCACCTTCACTCCCAGCCTGCGCCCCGATGCTGCGCGTTCTGTGCCTCCTGCGCCCCTGGAGGCCCCTTCGGGCCCGCGGCTGCGC
TTCCGACGGGGCGGCCGGGGGCTCAGAGATCCAAGTGCGCGCCCTGGCGGGTCCGGACCAAGGCTGTAGGTTCCATGAGGACAGGCCTTG
AGTCTGTCCTGGTCTCTGGAATCACGGTGTCTAGTAGAGGCCAGCACACAGCAAATATATAAATGTACAAATGAGTGAATGAAGAGAATC
TGATTGGCCTTAAGGAACTTACGCACTTAAAATAATTGGGCAGAAGAGAAGCAGTGAAGGAGTGCAGAGGCATCACCTGAAAGGGATCAC
TGAGATTCTGATGAACAGACCTTCTGCCCGCAATGCCTTGGGGAATGTCTTCGTCAGTGAGCTGCTGGAAACTCTGGCCCAGCTGCGGGA
GGACCGGCAAGTGCGTGTCCTGCTCTTCAGAAGTGGAGTGAAGGGCGTGTTCTGTGCAGGTGCAGACCTGAAGGAGCGGGAACAGATGAG
TGAAGCAGAGGTGGGGGTGTTTGTCCAGCGACTCCGGGGCCTGATGAATGACATCGCTTTGCAGTCCCCCAAAAGACCACGAAGTCCTGG
GAGTAATTCAAAGGTTCCTGAAATTGAGGTCACCGTGGAAGGCCCTAATAACAACAATCCTCAAACCTCAGCTGTTCGAACCCCGACCCA
GACTAACGGTTCTAACGTTCCCTTCAAGCCACGAGGGAGAGAGTTTTCCTTTGAGGCCTGGAATGCCAAAATCACGGACCTAAAACAGAA
AGTTGAAAATCTCTTCAATGAGAAATGTGGGGAAGCTCTTGGCCTTAAACAAGCTGTGAAGGTGCCGTTCGCGTTATTTGAGTCTTTCCC
GGAAGACTTTTATGTGGAAGGCTTACCTGAGGGTGTGCCATTCCGAAGACCATCGACTTTTGGCATTCCGAGGCTGGAGAAGATACTCAG
AAACAAAGCCAAAATTAAGTTCATCATTAAAAAGCCCGAAATGTTTGAGACGGCGATTAAGGAGAGCACCTCCTCTAAGAGCCCTCCCAG
AAAAATAAATTCATCACCCAATGTTAATACTACTGCATCAGGTGTTGAAGACCTTAACATCATTCAGGTGACAATTCCAGATGATGATAA
TGAAAGACTCTCGAAAGTTGAAAAAGCTAGACAGCTAAGAGAACAAGTGAATGACCTCTTTAGTCGGAAATTTGGTGAAGCTATTGGTAT
GGGTTTTCCTGTGAAAGTTCCCTACAGGAAAATCACAATTAACCCTGGCTGTGTGGTGGTTGATGGCATGCCCCCGGGGGTGTCCTTCAA
AGCCCCCAGCTACCTGGAAATCAGCTCCATGAGAAGGATCTTAGACTCTGCCGAGTTTATCAAATTCACGGTCATTAGACCATTTCCAGG
ACTTGTGATTAATAACCAGCTGGTTGATCAGAGTGAGTCAGAAGGCCCCGTGATACAAGAATCAGCTGAACCAAGCCAGTTGGAAGTTCC
AGCCACAGAAGAAATAAAAGAGACTGATGGAAGCTCTCAGATCAAGCAAGAACCAGACCCCACGTGGTAGACCTCTTCCCTCCTAGGCTT
AAAGTATCAGTGGTTGAGAAGAGCTTTTCGGACCTGTTACTACCCCAAGCTGTGTAATATACTTGTATAACAGAAATACCTTCTATACAA
ACCTTTTTTTCTACTTTTAGATAGAAATGTCTACTTTTTCAGCAGTTCTGTGAATTAAAGAGCAGAGTGACTGTGGGTCTGGAATGGCTG
GTGTACTTGGGAATGTACTATCAGGATTTTACAGCAATGCTGGGAAATGACAGGGAAAATGACAGGAATGAATCTCACCAGATTTTTTAT
GTACTCAGCAGAGCCTTGAGTTACGGTGTTTATTTTCCAATCAAGTGAAGATATCTCCTACTTCTCCTACTGGAACATCTCAGCTTCTGC
AGTGAAGAAAAATTCCTGTGATAGTTCAGTTCTTTAGTTTTTCTATTTGAAAAAAAAAAATCATTTAAATGATCCTTTGTTCACGGCTCT
CCTTAATGACTGAGTGAACAGTTCCTATCTGTATATTTGACTAAACCTTTTCCTAAGCTATCTCTCATGGTTCCTATGTTTTTTTATCAT
AATTAAAAGCAAAACCATCTGGATCACCTAACAGTCAGAGGTCAGTATCTCAGCGTGTGAATTATAGAGGAAATACAGAGAGAACCTCTT
CCACTTTTACTTTTCGTCCAAATAAAATGCATGGTGTACCAGAAGTTGAAGATCGGGTTGAGGATTGGGGCTAGCTCGATGACACTAAGG
CCCCAACATCGCGGGACCTGCTGTGGCGCGGATTCTTAGGAACGCTGTTCTAGCCGGCCCCCTCTCCAGGGGTCGCCGTGGCCGGCATTA
TTTCCTAGTTCTTCTTGTAACCCTGAGGTGCCAGCGCGGGGAGTGAGGAGGGGTCAGGGGGCTAAGGATGCAACCTCTGACGTTCTGCGC
CTTCCTAGGAGAGTCTTACATGTGTTGAGATTTCACAAGCAATGCGAGTTGTAAAATACCAGCTCTACAAGAAGCTAGGCTCTGTGACGG
CATAGTTTTCAGTAGCTTTATCACAATATTCACAATGGAGAATTATATGACATGGTAGCAGAAATAGGCCCTTTTATGTGTTGCTTCTAT
TTTACCTCAAATTGTAGATATAGGGTAATCAATAAAATCCATCCATGCCTTTCACACACTAAGTCA

>24892_24892_12_ECHDC2-GTF2I_ECHDC2_chr1_53373539_ENST00000541281_GTF2I_chr7_74160675_ENST00000416070_length(amino acids)=417AA_BP=166
MKGITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQMSEAEVGVFVQRLRGLMNDIALQSPKR
PRSPGSNSKVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREFSFEAWNAKITDLKQKVENLFNEKCGEALGLKQAVKVPFAL
FESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTASGVEDLNIIQVTI
PDDDNERLSKVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVI
RPFPGLVINNQLVDQSESEGPVIQESAEPSQLEVPATEEIKETDGSSQIKQEPDPTW

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ECHDC2-GTF2I


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ECHDC2-GTF2I


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ECHDC2-GTF2I


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneC0004238Atrial Fibrillation2CTD_human
TgeneC0175702Williams Syndrome2CTD_human
TgeneC0235480Paroxysmal atrial fibrillation2CTD_human
TgeneC2585653Persistent atrial fibrillation2CTD_human
TgeneC3468561familial atrial fibrillation2CTD_human
TgeneC0023467Leukemia, Myelocytic, Acute1CTD_human
TgeneC0026998Acute Myeloid Leukemia, M11CTD_human
TgeneC0086981Sicca Syndrome1CTD_human
TgeneC1266101Thymic epithelial tumor1CTD_human
TgeneC1510586Autism Spectrum Disorders1CTD_human
TgeneC1527336Sjogren's Syndrome1CTD_human
TgeneC1879321Acute Myeloid Leukemia (AML-M2)1CTD_human