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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:BTBD2-KIAA1109 (FusionGDB2 ID:HG55643TG84162)

Fusion Gene Summary for BTBD2-KIAA1109

check button Fusion gene summary
Fusion gene informationFusion gene name: BTBD2-KIAA1109
Fusion gene ID: hg55643tg84162
HgeneTgene
Gene symbol

BTBD2

KIAA1109

Gene ID

55643

84162

Gene nameBTB domain containing 2KIAA1109
Synonyms-ALKKUCS|FSA|Tweek
Cytomap('BTBD2')('KIAA1109')

19p13.3

4q27

Type of geneprotein-codingprotein-coding
DescriptionBTB/POZ domain-containing protein 2BTB (POZ) domain containing 2transmembrane protein KIAA1109fragile site-associated protein
Modification date2020032720200327
UniProtAcc

Q9BX70

.
Ensembl transtripts involved in fusion geneENST00000255608, ENST00000590646, 
Fusion gene scores* DoF score13 X 11 X 11=15734 X 5 X 3=60
# samples 185
** MAII scorelog2(18/1573*10)=-3.12744985908601
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(5/60*10)=-0.263034405833794
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: BTBD2 [Title/Abstract] AND KIAA1109 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointBTBD2(1990003)-KIAA1109(123107191), # samples:3
Anticipated loss of major functional domain due to fusion event.BTBD2-KIAA1109 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
BTBD2-KIAA1109 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across BTBD2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across KIAA1109 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4SARCTCGA-DX-A3U5-01ABTBD2chr19

1990003

-KIAA1109chr4

123107191

+
ChimerDB4SARCTCGA-DX-A3U5BTBD2chr19

1990002

-KIAA1109chr4

123107190

+


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Fusion Gene ORF analysis for BTBD2-KIAA1109

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000255608ENST00000495260BTBD2chr19

1990003

-KIAA1109chr4

123107191

+
5CDS-intronENST00000255608ENST00000495260BTBD2chr19

1990002

-KIAA1109chr4

123107190

+
In-frameENST00000255608ENST00000264501BTBD2chr19

1990003

-KIAA1109chr4

123107191

+
In-frameENST00000255608ENST00000264501BTBD2chr19

1990002

-KIAA1109chr4

123107190

+
In-frameENST00000255608ENST00000388738BTBD2chr19

1990003

-KIAA1109chr4

123107191

+
In-frameENST00000255608ENST00000388738BTBD2chr19

1990002

-KIAA1109chr4

123107190

+
In-frameENST00000255608ENST00000455637BTBD2chr19

1990003

-KIAA1109chr4

123107191

+
In-frameENST00000255608ENST00000455637BTBD2chr19

1990002

-KIAA1109chr4

123107190

+
intron-3CDSENST00000590646ENST00000264501BTBD2chr19

1990003

-KIAA1109chr4

123107191

+
intron-3CDSENST00000590646ENST00000264501BTBD2chr19

1990002

-KIAA1109chr4

123107190

+
intron-3CDSENST00000590646ENST00000388738BTBD2chr19

1990003

-KIAA1109chr4

123107191

+
intron-3CDSENST00000590646ENST00000388738BTBD2chr19

1990002

-KIAA1109chr4

123107190

+
intron-3CDSENST00000590646ENST00000455637BTBD2chr19

1990003

-KIAA1109chr4

123107191

+
intron-3CDSENST00000590646ENST00000455637BTBD2chr19

1990002

-KIAA1109chr4

123107190

+
intron-intronENST00000590646ENST00000495260BTBD2chr19

1990003

-KIAA1109chr4

123107191

+
intron-intronENST00000590646ENST00000495260BTBD2chr19

1990002

-KIAA1109chr4

123107190

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000255608BTBD2chr191990003-ENST00000264501KIAA1109chr4123107191+16170100517156645215
ENST00000255608BTBD2chr191990003-ENST00000455637KIAA1109chr4123107191+11690100517116893891
ENST00000255608BTBD2chr191990003-ENST00000388738KIAA1109chr4123107191+16176100517156645215
ENST00000255608BTBD2chr191990002-ENST00000264501KIAA1109chr4123107190+16170100517156645215
ENST00000255608BTBD2chr191990002-ENST00000455637KIAA1109chr4123107190+11690100517116893891
ENST00000255608BTBD2chr191990002-ENST00000388738KIAA1109chr4123107190+16176100517156645215

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000255608ENST00000264501BTBD2chr191990003-KIAA1109chr4123107191+0.0002489470.99975103
ENST00000255608ENST00000455637BTBD2chr191990003-KIAA1109chr4123107191+0.0004914220.9995086
ENST00000255608ENST00000388738BTBD2chr191990003-KIAA1109chr4123107191+0.000247380.9997526
ENST00000255608ENST00000264501BTBD2chr191990002-KIAA1109chr4123107190+0.0002489470.99975103
ENST00000255608ENST00000455637BTBD2chr191990002-KIAA1109chr4123107190+0.0004914220.9995086
ENST00000255608ENST00000388738BTBD2chr191990002-KIAA1109chr4123107190+0.000247380.9997526

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Fusion Genomic Features for BTBD2-KIAA1109


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
BTBD2chr191990002-KIAA1109chr4123107190+1.45E-081
BTBD2chr191990002-KIAA1109chr4123107190+1.45E-081
BTBD2chr191990002-KIAA1109chr4123107190+1.45E-081
BTBD2chr191990002-KIAA1109chr4123107190+1.45E-081

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for BTBD2-KIAA1109


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr19:1990003/chr4:123107191)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
BTBD2

Q9BX70

.
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneBTBD2chr19:1990002chr4:123107190ENST00000255608-5941_54329526.0Compositional biasNote=Poly-Ala
HgeneBTBD2chr19:1990003chr4:123107191ENST00000255608-5941_54329526.0Compositional biasNote=Poly-Ala
HgeneBTBD2chr19:1990002chr4:123107190ENST00000255608-59117_187329526.0DomainBTB
HgeneBTBD2chr19:1990003chr4:123107191ENST00000255608-59117_187329526.0DomainBTB
TgeneKIAA1109chr19:1990002chr4:123107190ENST000002645015861154_11571195006.0Compositional biasNote=Poly-Ser
TgeneKIAA1109chr19:1990002chr4:123107190ENST000002645015861226_12331195006.0Compositional biasNote=Poly-Ser
TgeneKIAA1109chr19:1990002chr4:123107190ENST000002645015861237_12401195006.0Compositional biasNote=Poly-Ser
TgeneKIAA1109chr19:1990002chr4:123107190ENST000002645015861417_14211195006.0Compositional biasNote=Poly-Lys
TgeneKIAA1109chr19:1990002chr4:123107190ENST000002645015861544_15471195006.0Compositional biasNote=Poly-Ser
TgeneKIAA1109chr19:1990002chr4:123107190ENST000002645015861991_19941195006.0Compositional biasNote=Poly-Pro
TgeneKIAA1109chr19:1990002chr4:123107190ENST000002645015863838_38411195006.0Compositional biasNote=Poly-Lys
TgeneKIAA1109chr19:1990002chr4:123107190ENST000002645015864110_41581195006.0Compositional biasNote=Ser-rich
TgeneKIAA1109chr19:1990002chr4:123107190ENST00000264501586772_7791195006.0Compositional biasNote=Poly-Ser
TgeneKIAA1109chr19:1990002chr4:123107190ENST000003887383841154_11571195006.0Compositional biasNote=Poly-Ser
TgeneKIAA1109chr19:1990002chr4:123107190ENST000003887383841226_12331195006.0Compositional biasNote=Poly-Ser
TgeneKIAA1109chr19:1990002chr4:123107190ENST000003887383841237_12401195006.0Compositional biasNote=Poly-Ser
TgeneKIAA1109chr19:1990002chr4:123107190ENST000003887383841417_14211195006.0Compositional biasNote=Poly-Lys
TgeneKIAA1109chr19:1990002chr4:123107190ENST000003887383841544_15471195006.0Compositional biasNote=Poly-Ser
TgeneKIAA1109chr19:1990002chr4:123107190ENST000003887383841991_19941195006.0Compositional biasNote=Poly-Pro
TgeneKIAA1109chr19:1990002chr4:123107190ENST000003887383843838_38411195006.0Compositional biasNote=Poly-Lys
TgeneKIAA1109chr19:1990002chr4:123107190ENST000003887383844110_41581195006.0Compositional biasNote=Ser-rich
TgeneKIAA1109chr19:1990002chr4:123107190ENST00000388738384772_7791195006.0Compositional biasNote=Poly-Ser
TgeneKIAA1109chr19:1990002chr4:123107190ENST000004556373641154_11571193681.0Compositional biasNote=Poly-Ser
TgeneKIAA1109chr19:1990002chr4:123107190ENST000004556373641226_12331193681.0Compositional biasNote=Poly-Ser
TgeneKIAA1109chr19:1990002chr4:123107190ENST000004556373641237_12401193681.0Compositional biasNote=Poly-Ser
TgeneKIAA1109chr19:1990002chr4:123107190ENST000004556373641417_14211193681.0Compositional biasNote=Poly-Lys
TgeneKIAA1109chr19:1990002chr4:123107190ENST000004556373641544_15471193681.0Compositional biasNote=Poly-Ser
TgeneKIAA1109chr19:1990002chr4:123107190ENST000004556373641991_19941193681.0Compositional biasNote=Poly-Pro
TgeneKIAA1109chr19:1990002chr4:123107190ENST000004556373643838_38411193681.0Compositional biasNote=Poly-Lys
TgeneKIAA1109chr19:1990002chr4:123107190ENST000004556373644110_41581193681.0Compositional biasNote=Ser-rich
TgeneKIAA1109chr19:1990002chr4:123107190ENST00000455637364772_7791193681.0Compositional biasNote=Poly-Ser
TgeneKIAA1109chr19:1990003chr4:123107191ENST000002645015861154_11571195006.0Compositional biasNote=Poly-Ser
TgeneKIAA1109chr19:1990003chr4:123107191ENST000002645015861226_12331195006.0Compositional biasNote=Poly-Ser
TgeneKIAA1109chr19:1990003chr4:123107191ENST000002645015861237_12401195006.0Compositional biasNote=Poly-Ser
TgeneKIAA1109chr19:1990003chr4:123107191ENST000002645015861417_14211195006.0Compositional biasNote=Poly-Lys
TgeneKIAA1109chr19:1990003chr4:123107191ENST000002645015861544_15471195006.0Compositional biasNote=Poly-Ser
TgeneKIAA1109chr19:1990003chr4:123107191ENST000002645015861991_19941195006.0Compositional biasNote=Poly-Pro
TgeneKIAA1109chr19:1990003chr4:123107191ENST000002645015863838_38411195006.0Compositional biasNote=Poly-Lys
TgeneKIAA1109chr19:1990003chr4:123107191ENST000002645015864110_41581195006.0Compositional biasNote=Ser-rich
TgeneKIAA1109chr19:1990003chr4:123107191ENST00000264501586772_7791195006.0Compositional biasNote=Poly-Ser
TgeneKIAA1109chr19:1990003chr4:123107191ENST000003887383841154_11571195006.0Compositional biasNote=Poly-Ser
TgeneKIAA1109chr19:1990003chr4:123107191ENST000003887383841226_12331195006.0Compositional biasNote=Poly-Ser
TgeneKIAA1109chr19:1990003chr4:123107191ENST000003887383841237_12401195006.0Compositional biasNote=Poly-Ser
TgeneKIAA1109chr19:1990003chr4:123107191ENST000003887383841417_14211195006.0Compositional biasNote=Poly-Lys
TgeneKIAA1109chr19:1990003chr4:123107191ENST000003887383841544_15471195006.0Compositional biasNote=Poly-Ser
TgeneKIAA1109chr19:1990003chr4:123107191ENST000003887383841991_19941195006.0Compositional biasNote=Poly-Pro
TgeneKIAA1109chr19:1990003chr4:123107191ENST000003887383843838_38411195006.0Compositional biasNote=Poly-Lys
TgeneKIAA1109chr19:1990003chr4:123107191ENST000003887383844110_41581195006.0Compositional biasNote=Ser-rich
TgeneKIAA1109chr19:1990003chr4:123107191ENST00000388738384772_7791195006.0Compositional biasNote=Poly-Ser
TgeneKIAA1109chr19:1990003chr4:123107191ENST000004556373641154_11571193681.0Compositional biasNote=Poly-Ser
TgeneKIAA1109chr19:1990003chr4:123107191ENST000004556373641226_12331193681.0Compositional biasNote=Poly-Ser
TgeneKIAA1109chr19:1990003chr4:123107191ENST000004556373641237_12401193681.0Compositional biasNote=Poly-Ser
TgeneKIAA1109chr19:1990003chr4:123107191ENST000004556373641417_14211193681.0Compositional biasNote=Poly-Lys
TgeneKIAA1109chr19:1990003chr4:123107191ENST000004556373641544_15471193681.0Compositional biasNote=Poly-Ser
TgeneKIAA1109chr19:1990003chr4:123107191ENST000004556373641991_19941193681.0Compositional biasNote=Poly-Pro
TgeneKIAA1109chr19:1990003chr4:123107191ENST000004556373643838_38411193681.0Compositional biasNote=Poly-Lys
TgeneKIAA1109chr19:1990003chr4:123107191ENST000004556373644110_41581193681.0Compositional biasNote=Ser-rich
TgeneKIAA1109chr19:1990003chr4:123107191ENST00000455637364772_7791193681.0Compositional biasNote=Poly-Ser

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneKIAA1109chr19:1990002chr4:123107190ENST0000026450158626_461195006.0TransmembraneHelical
TgeneKIAA1109chr19:1990002chr4:123107190ENST0000038873838426_461195006.0TransmembraneHelical
TgeneKIAA1109chr19:1990002chr4:123107190ENST0000045563736426_461193681.0TransmembraneHelical
TgeneKIAA1109chr19:1990003chr4:123107191ENST0000026450158626_461195006.0TransmembraneHelical
TgeneKIAA1109chr19:1990003chr4:123107191ENST0000038873838426_461195006.0TransmembraneHelical
TgeneKIAA1109chr19:1990003chr4:123107191ENST0000045563736426_461193681.0TransmembraneHelical


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Fusion Gene Sequence for BTBD2-KIAA1109


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>10454_10454_1_BTBD2-KIAA1109_BTBD2_chr19_1990002_ENST00000255608_KIAA1109_chr4_123107190_ENST00000264501_length(transcript)=16170nt_BP=1005nt
CACGCCGCAGCCACAAAATGGCGGCGGGTGGGAGCGGCGGGCGTGCGTCGTGCCCGCCGGGGGTCGGGGTCGGCCCGGGCACGGGGGGCA
GTCCCGGGCCCAGCGCCAACGCCGCCGCCACCCCGGCCCCCGGCAACGCGGCCGCCGCCGCCGCCGCCGCCGCCGCCGCCGCCGCCGCCC
CTGGGCCGACGCCGCCCGCCCCGCCGGGCCCCGGGACAGACGCGCAGGCCGCGGGCGCGGAGCGGGCGGAGGAGGCGGCGGGCCCGGGGG
CGGCGGCGCTGCAGCGCGAGGCCGCGTACAACTGGCAGGCCAGCAAGCCCACCGTGCAGGAGCGCTTCGCCTTCCTCTTCAACAACGAGG
TGCTGTGCGACGTGCACTTCCTGGTGGGCAAGGGGCTCAGCTCGCAGCGCATCCCCGCGCACAGGTTCGTGCTGGCCGTGGGCAGCGCCG
TCTTTGATGCCATGTTCAACGGGGGAATGGCCACAACATCCACGGAGATTGAGCTGCCCGACGTGGAACCCGCTGCCTTCCTCGCACTGC
TCAAGTTTCTCTACTCGGACGAGGTGCAGATTGGCCCGGAGACGGTGATGACCACGCTATACACCGCCAAGAAGTACGCGGTGCCAGCGC
TCGAGGCCCATTGCGTGGAGTTCCTGAAGAAGAACCTGCGAGCCGACAACGCCTTCATGCTGCTCACGCAGGCGCGACTCTTCGATGAAC
CGCAGCTGGCCAGCCTGTGCCTGGAGAACATCGACAAAAACACTGCAGACGCCATCACCGCGGAGGGCTTCACCGACATTGACCTGGACA
CGCTGGTGGCTGTCCTGGAGCGCGACACACTGGGCATCCGTGAGGTGCGGCTGTTCAATGCCGTTGTCCGCTGGTCCGAGGCCGAGTGTC
AGCGGCAGCAGCTGCAGGTGACGCCAGAGAACAGGCGGAAGGTTCTGGGCAAGGCCCTGGGCCTCATTCGCTTCCCGCTCATGACCATCG
AGGAGTTCGCTGCAGATCCAAAGGCAGAAACCAGGTTATACATCACAGTCAATGACTTTGAATTTCATGTCTATAATCGCTCGGATCTTT
ATGGACGCCTTCAAGAGTTGTTTGGTTTGGAGCCAACAATAATTCCACCTAAGAAAGATGATGATAAAACACGGGAAATTGGAAGAACAA
GAACCCAATCGAAAATTGAAAGAGTTAAAGTAAAAACAGAATCCCAAGACCCCACATCTTCATGGAGATCACTTATTCCAGTCATAAAGG
TCAATGTGAGCACAGGACGTTTGGCCTTTGGAAATCACTACCAGCCGCAAACTCTGTGCATCAACTTTGATGATGCTTTCTTAACTTATA
CTACAAAACCACCTTCAAGTCATCTTGACCAATTCATGCATATTGTGAAAGGAAAGCTTGAAAATGTTCGAGTCATGCTTGTTCCTAGTC
CAAGATATGTTGGTCTTCAAAATGATGAACCACCGAGATTAATGGGAGAAGGTTTTGTGGTGATGCAGTCAAATGATGTTGACATCTACT
ACTACATGGATGAGCCAGGACTTGTTCCGGAAGAAACAGAAGAAAATATTGAAGGAGAAATGAGCAGTGAGGATTGCAAATTACAAGACT
TGCCTCCATGTTGGGGACTGGATATAGTTTGTGGTAAAGGAACAGATTTTAATTATGGACCATGGGCCGATAGGCAGAGAGATTGTTTGT
GGAAGTTTTTCTTTCCACCTGACTATCAAGTTCTGAAAGTTTCTGAAATTGCACAGCCTGGGAGACCAAGACAGATCCTTGCTTTTGAAT
TACGAATGAATATTATTGCAGATGCTACAATTGATTTGCTGTTTACCAAAAATAGGGAAACAAATGCTGTACATGTAAATGTAGGAGCTG
GCTCATATTTAGAAATTAATATTCCAATGACAGTTGAAGAAAATGGTTACACTCCTGCTATTAAGGGACAACTCTTACATGTGGATGCCA
CTACCAGCATGCAATATCGGACCCTTTTAGAAGCAGAAATGTTAGCATTCCACATCAATGCCAGCTACCCCCGAATATGGAACATGCCGC
AGACATGGCAGTGTGAATTAGAGGTTTATAAAGCCACTTACCACTTCATCTTTGCACAGAAAAACTTCTTTACAGATTTAATTCAAGACT
GGTCTAGTGACAGTCCTCCAGACATTTTTTCATTTGTTCCATATACGTGGAATTTTAAAATCATGTTTCATCAGTTTGAAATGATTTGGG
CTGCTAATCAACACAATTGGATCGACTGTTCTACTAAACAACAGGAAAATGTGTATCTGGCAGCCTGTGGAGAAACACTAAACATTGATT
TTTCTTTGCCTTTTACGGACTTTGTTCCAGCTACATGTAATACCAAGTTCTCTTTAAGAGGAGAAGATGTTGATCTTCATTTGTTTCTAC
CAGACTGCCACCCTAGTAAATATTCTTTATTTATGCTGGTAAAAAATTGCCATCCAAATAAGATGATTCATGATACTGGTATTCCTGCTG
AGTGTCAAAGTGGCCAGAAAACAGTTAAACCAAAATGGCGCAACGTTACTCAGGAAAAGTCTGGTTGGGTTGAATGCTGGACTGTCCCAA
GTGTCATGCTTACAATTGATTATACATGGCATCCAATTTATCCACAAAAAGCAGATGAACAGCTGAAACAATCATTATCAGAAATGGAAG
AGACAATGCTATCTGTATTAAGGCCATCCCAGAAGACATCAGACAGAGTTGTTTCTTCTCCCTCTACTTCTTCACGCCCACCTATTGATC
CCTCAGAACTTCCACCTGATAAACTTCATGTAGAAATGGAACTTTCTCCAGATTCTCAGATAACTCTCTATGGACCTCTACTAAATGCCT
TTTTGTGTATAAAGGAAAACTACTTTGGGGAAGATGACATGTATATGGATTTTGAAGAGGTTATCTCAAGTCCTGTTTTGTCACTGTCAA
CATCATCCAGCTCTGGGTGGACTGCTGTTGGAATGGAAAATGACAAAAAGGAAAATGAAGGTTCAGCCAAGTCAATTCATCCACTTGCCT
TGCGTCCTTGGGATATTACTGTACTTGTTAATTTGTACAAAGTTCATGGGCGTCTTCCTGTTCATGGAACTACTGATGGTCCTGAATGCC
CTACAGCTTTCTTGGAAAGACTATGTTTTGAAATGAAAAAAGGATTTAGGGAGACCATGCTGCAACTTATCCTGTCACCCCTGAATGTGT
TTGTCAGTGATAACTATCAGCAGCGACCCCCTGTGGATGAAGTACTCAGGGAAGGTCACATCAATTTGTCAGGTCTCCAGCTGAGAGCAC
ACGCTATGTTCTCAGCAGAAGGTCTTCCTTTGGGAAGCGATTCCTTAGAATACGCATGGTTAATTGATGTGCAGGCTGGAAGTCTTACAG
CTAAGGTCACAGCACCACAGCTGGCATGCCTCTTGGAGTGGGGACAGACATTTGTTTTTCATGTGGTATGTCGGGAGTATGAACTGGAAA
GACCGAAATCAGTTATAATATGTCAGCATGGAATTGATCGTCGGTTCTGTGAATCCAAGTTGAGTTGTATTCCTGGGCCTTGTCCAACTT
CAGATGATTTGAAATATACTATGATTCGTTTAGCAGTAGATGGAGCCGATATTTACATTGTTGAGCATGGTTGTGCTACAAATATAAAGA
TGGGTGCAATTCGAGTTGCAAACTGTAATCTCCACAATCAATCGGTTGGGGAAGGAATCAGTGCTGCAATTCAGGATTTTCAAGTGAGAC
AGTACATTGAGCAATTAAATAATTGCAGAATTGGACTTCAGCCTGCAGTGCTACGGAGGGCCTATTGGCTTGAAGCTGGGTCAGCCAATT
TAGGACTTATTACTGTTGATATTGCTTTAGCTGCTGACCATCATTCTAAACATGAGGCACAAAGACATTTCTTAGAAACTCATGATGCCA
GAACTAAGAGGTTGTGGTTTTTATGGCCAGATGATATCCTGAAGAATAAGAGGTGTAGAAACAAATGTGGTTGTCTCGGTGGCTGCAGAT
TCTTTGGTGGCACAGTAACTGGCCTAGATTTCTTCAAACTTGAAGAGTTGACACCTTCCAGTAGCTCTGCATTTTCAAGCACAAGTGCAG
AGTCTGATATGTATTATGGACAGTCTCTGCTACAGCCTGGAGAATGGATAATTACTAAAGAAATTCCCAAAATTATAGATGGTAATGTGA
ATGGCATGAAGAGGAAAGAATGGGAAAACAAATCAGTGGGAATAGAAGTAGAGAGAAAAACTCAGCACCTTAGTCTTCAAGTACCATTAC
GATCTCATAGTTCATCCTCTTCCTCAGAAGAGAACAGTAGTTCTAGTGCTGCACAGCCTTTGTTGGCTGGTGAAAAGGAAAGTCCTTCAT
CTGTTGCTGATGACCATTTGGTTCAAAAAGAGTTCTTGCATGGGACAAAAAGAGATGATGGCCAAGCAAGTATCCCTACAGAAATTTCAG
GAAACAGCCCTGTGTCTCCTAATACTCAGGATAAGTCAGTAGGTCAATCTCCTCTTAGATCTCCCTTGAAACGACAAGCCTCTGTCTGTT
CCACCCGTCTTGGAAGTACTAAGAGTCTTACTGCTGCTTTCTATGGGGACAAGCAGCCTGTAACAGTTGGAGTCCAGTTTAGTAGTGATG
TCTCTCGAAGTGATGAGAATGTACTAGACTCACCAAAGCAGAGGAGAAGTTTTGGTTCATTCCCATATACACCATCAGCAGACTCTAATT
CATTTCATCAGTATCGATCAATGGATTCCAGCATGTCAATGGCTGATAGTGAAGCCTACTTTTCTGCTGCTGAGGAATTTGAGCCCATTA
GCAGTGATGAAGGCCCTGGAACTTATCCGGGTAGAAAAAAGAAGAAAAAGCAAACCCAGCAGATTGACTACAGTAGGGGTTCCATATATC
ACAGTGTAGAAGGGCCACTTACTGGACATGGAGAAAGCATTCAGGATTCCAGAACTCTGCCATTCAAAACTCATCCTTCTCAGGCTTCAT
TTGTTTCTGCGTTAGGTGGAGAAGATGATGTTATAGAACATCTATATATTGTAGAAGGTGAGAAAACAGTGGAGAGTGAACAGATTACTC
CGCAACAACCCGTGATGAATTGTTATCAGACTTACCTTACTCAGTTCCAGGTAATTAATTGGTCAGTTAAGCACCCAACCAACAAAAGAA
CCTCTAAATCCTCATTGCATCGTCCCCTTGATCTGGATACACCAACCAGTGAAGAAAGTTCATCGTCATTTGAACAGCTTTCTGTTCCAA
CTTTTAAGGTTATCAAGCAGGGGCTCACAGCTAATTCTTTGCTAGACAGAGGCATGCAACTTTCAGGATCAACTTCAAATACGCCGTATA
CTCCATTGGAAAAAAAACTCGCTGATAACACAGATGATGAAACATTAACAGAAGAGTGGACCCTGGATCAACCAGTGTCCCAGACCAGGA
CAACAGCCATAGTTGAAGTAAAAGGAACTGTTGATATTGTTTTGACTCCCCTGGTGGCTGAAGCTTTAGACAGATATATTGAAGCAATGG
TTCATTGTGCTAGTACCCGACATCCAGCTGCAATTGTAGATGATCTTCATGCTAAAGTCCTCAGGGAAGCTGTCCAAAATAGCAAGACTA
CCTTTTCAGAAAATTTATCTTCCAAACAAGACATTAGAGGAACAAAAACTGAGCAGTCTACAATAGGAACGACTAACCAAGGACAAGCAC
AGACAAATCTTACAATGAAGCAAGATAATGTAACAATTAAAGGTCTTCAGACTAATGTTAGCATACCAAAGGTAAACTTATGTTTGTTAC
AAGCCTCAGTGGAAGAATCTCCAACTACGGCTCCTAGTAGGAGTGTGACTCATGTTTCCCTAGTGGCATTGTGTTTTGACAGAATTGCTA
CACAGGTTCGCATGAACAGAGGTGTGGTTGAAGAGACTTCAAACAATGCAGAACCTGGTAGAACATCAAATTTTGATAGGTATGTTCATG
CCACAAAGATGCAGCCTCAGTCATCTGGATCTCTCAGATCAAATGCTGGAGCAGAAAAAGGCAAAGAAATTGCAGCTAAGTTAAACATTC
ATCGAGTTCATGGGCAACTTAGGGGTCTTGATACAACAGACATTGGGACCTGTGCAATCACTGCTATTCCTTTTGAGAAGTCCAAAGTTT
TATTTACTCTTGAAGAGTTGGATGAATTTACTTTTGTGGATGAAACTGATCAGCAAGCTGTTCCAGATGTAACTCGAATAGGTCCCAGCC
AAGAAAAATGGGGATGGATAATGTTTGAATGTGGACTTGAAAATTTAACCATAAAAGGAGGAAGACAGTCTGGTGCTGTTTTATATAACA
GTTTTGGAATTATGGGTAAAGCTAGTGACACAGAAAGGGGTGGAGTGCTGACATCCAATAATTCTTCTGATTCTCCAACCGGCAGTGGCT
ATAATACTGATGTCTCTGATGATAATCTTCCATGTGACCGGACAAGCCCTTCCTCAGACTTAAATGGAAATTCTGTTTCAGATGAACAGG
ATGAAGGAGTCGAATCTGATGATTTGAAAAAAGATCTACCTCTGATGCCTCCTCCTCCAGATTCATGTAGCATGAAGTTGACCATTAAAG
AAATTTGGTTTAGTTTTGCAGCTCCCACCAATGTGAGATCTCACACACATGCATTTTCTAGGCAGCTGAACCTTTTAAGCACTGCAACAC
CAGCTGTTGGTGCATGGCTTGTTCCCATTGACCAACTCAAGTCATCTTTAAACAAATTGGAAACTGAGGGAACCTTGAGAATTTGTGCTG
TTATGGGATGCATAATGACAGAAGCATTAGAGAATAAAAGTGTACATTTTCCCCTAAGAAGTAAATACAACAGGCTTACAAAAGTTGCTC
GCTTTCTCCAAGAAAATCCTTCATGTTTACTATGTAATATACTACACCACTATCTGCACCAGGCAAATTACTCCATCATTGATGATGCTA
CAATGAGCGATGGACTTCCTGCTTTGGTAACTTTGAAGAAAGGTTTAGTTGCACTGGCAAGGCAGTGGATGAAGTTTATTGTGGTGACAC
CAGCCTTTAAAGGAGTTAGCTTACATAGACCAGCTCAGCCTCTGAAACCTCAAATAGCTATGGACCATGAACATGAAGATGGACTTGGAT
TGGACAATGGGGGTGGTCTTCAAAGTGATACCAGTGCTGATGGAGCAGAATTTGAGTTCGATGCAGCCACAGTCAGTGAACACACAATGC
TATTAGAAGGAACAGCTAACCGGCCTCCACCTGGTAGCTCTGGACCTGTAACTGGAGCTGAGATAATGAGGAAACTTTCTAAAACTCATA
CCCATAGTGACTCTGCATTAAAAATAAAGGGCATTCACCCATATCATTCTCTGAGCTATACCAGTGGAGACACTGCCACTGATTCTCCAG
TGCATGTTGGACGTGCTGGGATGCCAGTAAAGGACAGTCCAAGGAAGGAGAGCCTACTCAGCTACCTGACTGGAAGCTTCCCAAGCCTGC
ACAACCTCCTGGAAGGTACTCCTCAGAGAAGCAGTGCTGCTGTGAAAAGTAGCTCCCTAACGAGAACAGGAAATACAGTAGCCACTGATA
TGTTATCTGAACATCCCTTGCTATCTGAGCCATCATCTGTGAGTTTCTATAATTGGATGTCAAATGCTGTGGGTAATCGAGGAAGTGTGT
TACAAGAATCTCCTGTTACAAAATCAGGACACAATAGTCTTCCCACAGGTGTTGCACCCAATCTTCCAACAATACCCTCAGCCTCAGATT
TCAACACTGTCTTGTCTAGTGACCAAAATACTTTGGATGGGACACATTCTCAGCATAGCACCAGTCAGGATGATGTGGCAGGTGTAGAAG
AAGCAAACCAAGGGTTTCCTGCTGTTCAGCTTGCTGATGCACAGGTTGTTTTCAAGCCTCTTCTGAGTCATACAGGGATCCAGTCACAGG
ATACAATGCCATTCTGCTACCGAATGTACTTTGGAGAACACCTTTCATTTTCAGGGACTTTGGACTGCCTCAGAGCAGATATTGTGGATT
CAGACACAGCCAAAGAGAGAAAAGGCAAAAGAGCAAGAAGGCAAGGCCATGTGAATCTTCCTCCACTTGAGTTCAAACCAGCATTAATGT
TGGGAACCTTTAGCATCAGTGCTGTTGTAATGGAAAAGTCCGTGTGCACCCCTCAGAACTCTACCAGTGCCCTTTCTTTTCATGATCTCA
GCAAGCGGTATTATAACACCTTTCACTGCAACTTTACTATTTCCTGTCAGTCAATAAGCCAGCATGTAGATATGGCTTTGGTTCGTCTTA
TTCATCAGTTTAGCACAATGATAGATGACATCAAAGCAACTCAGACTGATATTAAACTTAGCAGATATACAGCCGGATCTGCTTCCCCAA
CACCTACCTTCAAAACCAGAAAACATCGGGACTTTCGTTCATCTGACTTTAGCCGCAGTTCTAGAGGAAGTCTTAATGGTGGCAATAGAG
TAAATAATGCAAAGAACAAACGGACCAACAATGAGAATAACAAAAAGGAATCTCGAAACAAGAATTCATTAGGAAGATCTGAAAGAAGAA
CATCAAAAGTGTCTAGGAAAGGTTCAAAAGATGTGGTGGATCACATGACTATTCATATGGATGACTCTGATTCAATTACAGTGTCAGAAC
AAAGTGAGCCTTCAGCTGAGTGCTGGCAGAATATGTATAAATTGCTTAACTTCTATTCACTTATCTCCGATCCAACAGGAATATTGGAAA
AGTCTTCAGAAACATTTGGACCAGCAGGAGTTCGGAGCCCTACAGAGCCAACATGTAAAGTTGTGTTTGAGAATGAACAAGACAACAGCA
GTTTGACTAAGACTCAGAGGAAACGTAGCTTGGTAACTTCTGAACCTCAGCATGTTACTCTAATAGTGTTTGGGATTGGCATGGTGAACC
GCACACACCTAGAGGCAGATATTGGTGGACTAACAATGGAATCAGAACTGAAGAGGATCCATGGCAGTTTTACTCTTAAGGAAAAAATGA
AAGATGTTTTACATCAAAAGATGACTGAGACTTGTGCTACTGCTCATATTGGTGGGGTTAATATTGTGCTGCTTGAAGGGATTACACCAA
ATATACAACTGGAGGATTTTCCTACATCTCCTACAAGTACAGCCAAACAAGAGTTTCTAACTGTAGTGAAATGTAGTATTGCCAAGTCCC
AAGCCCTCTACAGTGCCCAAAGAGGGCTGAAGACAAACAATGCTGCTGTGTTCAAAGTAGGAGCTATCAGTATCAACATTCCTCAGCACC
CTGCCACCTTACATAGCATGATGGTTCGAAGTTCTCACCAACTATCTAAACAAATCTCAGACCTAATCAGACAGCCTTCTACAGCCCCAC
AGCCTGTAAAAGAAGATATTGCAACCCCACTACCTTCTGAAAAAACCCCAACAAGTGTTAATCAAACTCCTGTTGAAACAAATGAATTTC
CTCAGCTACCAGAAGGCTTAGAAAAGAAGCCTATTGTTCTTAAATTCAGTGCCATGTTAGATGGTATAGCCATTGGAGCAGCACTTTTAC
CATCTCTGAAAGCAGAATACAAGATGGGAAGAATGAGAAGTCATGGAATGACAGGTGCACAGACAAGATTTACATTTGAGCTGCCAAATC
ACAGATTGCGTTTTACTTCAAAAGTTTCTGCCACAGATATGTCAACCATTCCTCCTTCTGCCAGTCTTAACCTTCCCCCTGTTACCATGT
CAGGGAAATATATAATGGAAGAACATGATAGTTATTCGGATCAGGTGTGGAGTATAGATGAACTGCCTTCTAAACAAGGTTACTATTTAC
AGGGAAATTATCTGCGTTGTGTGGCAGAAGTTGGTTCCTTTGAACATAATCTTACAACTGATCTTCTAAACCACTTGGTATTTGTACAGA
AAGTGTTCATGAAGGAAGTTAATGAAGTAATACAAAAAGTTTCTGGTGGGGAGCAGCCTATTCCTCTCTGGAACGAACATGATGGAACAG
CAGATGGAGATAAACCTAAAATTCTCCTCTATTCCCTAAACTTGCAGTTCAAGGGTATTCAAGTAACGGCCACTACTCCATCAATGAGAG
CTGTAAGATTTGAAACTGGATTGATTGAACTGGAACTTTCTAACCGACTTCAAACCAAAGCTTCACCAGGAAGTAGCAGCTATCTGAAAC
TGTTTGGCAAATGCCAGGTGGATTTAAATCTGGCATTAGGACAAATTGTCAAACATCAGGTTTATGAGGAAGCTGGTTCTGATTTTCATC
AAGTTGCCTATTTTAAAACCAGAATTGGATTAAGAAATGCCCTCCGAGAAGAAATCAGTGGTTCTTCAGATAGGGAAGCTGTGCTTATTA
CTTTGAATAGACCAATTGTTTATGCACAGCCTGTGGCCTTTGATAGAGCTGTGCTGTTTTGGCTGAATTATAAGGCCGCCTATGACAACT
GGAATGAACAACGAATGGCTTTACATAAGGATATTCATATGGCTACAAAGGAAGTAGTAGATATGCTACCTGGTATCCAGCAAACATCAG
CCCAGGCCTTTGGGACTCTTTTTCTCCAGCTCACTGTCAATGATCTGGGAATTTGCCTACCTATCACAAATACTGCACAGTCTAATCATA
CTGGAGACCTTGACACTGGTTCTGCTTTGGTATTAACCATTGAAAGTACTCTCATCACTGCATGCTCTTCAGAGTCTCTGGTTAGCAAAG
GGCATTTCAAAAACTTTTGTATCCGTTTTGCTGATGGATTTGAGACATCATGGGATGACTGGAAACCAGAAATTCATGGGGATTTAGTGA
TGAATGCCTGTGTAGTTCCAGATGGCACCTATGAAGTATGTTCAAGAACTACAGGACAAGCAGCAGCTGAAAGCAGTAGTGCTGGAACCT
GGACACTCAACGTATTGTGGAAAATGTGTGGGATTGATGTTCACATGGATCCTAACATTGGCAAAAGGCTTAATGCTCTGGGCAATACTC
TTACAACACTGACAGGAGAGGAAGACATAGATGACATTGCTGACTTAAATTCAGTGAACATAGCTGACCTGTCAGATGAGGATGAAGTTG
ATACTATGTCTCCCACTATCCATACTGAAGCCACAGATTATCGAAGACAGGCAGCATCTGCTAGCCAGCCGGGAGAACTTAGAGGAAGAA
AAATTATGAAGCGTATAGTGGATATCAGAGAACTGAATGAACAGGCCAAAGTAATAGATGATCTGAAAAAATTAGGTGCAAGTGAAGGAA
CCATAAACCAGGAAATTCAACGTTACCAACAGTTAGAATCTGTGGCTGTGAATGACATTAGAAGAGATGTTCGTAAAAAATTACGGAGGT
CCAGTATGCGGGCTGCTTCCCTAAAGGATAAGTGGGGTTTGAGTTACAAACCAAGTTACAGCCGATCAAAAAGCATTTCTGCTTCTGGAA
GACCACCTCTTAAGCGAATGGAAAGGGCAAGTTCTCGAGTAGGAGAAACTGAAGAGCTCCCAGAAATCCGTGTGGATGCAGCATCTCCTG
GACCTAGAGTAACTTTTAATATCCAGGATACATTTCCAGAGGAGACAGAACTGGACCTTTTGTCAGTAACCATTGAAGGTCCATCCCATT
ATTCATCAAATAGTGAAGGATCATGTTCTGTGTTCAGTTCTCCCAAAACTCCAGGAGGCTTTTCACCAGGCATTCCTTTCCAAACTGAAG
AGGGCCGACGGGATGACAGTTTGTCTTCTACCAGTGAAGATTCCGAGAAGGATGAAAAAGATGAAGACCATGAGAGGGAAAGGTTTTATA
TTTACAGGAAACCCTCACATACGTCTCGTAAAAAAGCAACAGGCTTTGCTGCTGTTCATCAGCTATTTACAGAACGCTGGCCAACAACAC
CAGTCAATAGAAGTCTTAGTGGCACAGCTACAGAGAGAAATATTGACTTTGAACTTGATATACGGGTTGAAATTGATAGTGGAAAATGTG
TACTCCACCCAACCACCCTTCTACAAGAACATGATGATATAAGTTTGAGAAGGAGTTATGATCGAAGTTCCAGGAGCTTAGATCAAGATT
CACCTTCAAAAAAGAAGAAGTTTCAAACTAATTATGCTTCTACCACCCATTTAATGACCGGCAAGAAAGTGCCATCATCTCTACAGACAA
AGCCTAGTGACTTAGAAACAACAGTATTTTACATTCCCGGAGTTGATGTAAAGTTGCATTACAATTCCAAGACGCTAAAGACTGAATCAC
CTAATGCCTCCAGGGGATCTTCCTTGCCAAGAACACTGTCCAAAGAGTCCAAGCTGTATGGTATGAAAGATAGTGCAACATCTCCTCCTT
CTCCTCCTTTACCTTCCACTGTCCAGAGCAAGACTAACACCTTACTTCCTCCCCAGCCCCCACCTATTCCTGCAGCCAAAGGAAAAGGAA
GTGGAGGAGTAAAAACAGCCAAGTTATATGCCTGGGTAGCACTTCAGTCATTGCCAGAAGAAATGGTTATTAGTCCCTGCCTATTAGACT
TTCTGGAAAAAGCTCTGGAAACTATCCCAATTACACCAGTTGAAAGGAATTATACAGCTGTCAGCTCACAAGATGAAGATATGGGACATT
TTGAAATACCAGATCCTATGGAAGAATCAACAACATCACTAGTGTCGTCTTCAACATCTGCTTACTCTTCCTTCCCTGTAGATGTTGTGG
TTTATGTACGAGTTCAGCCCTCACAGATCAAATTTAGCTGTTTACCAGTATCAAGAGTAGAATGCATGTTAAAGCTGCCATCCCTGGATT
TGGTGTTTTCTTCAAACCGAGGAGAACTGGAGACTTTAGGGACTACATATCCTGCAGAGACTTTATCCCCTGGAGGTAATGCTACTCAGA
GTGGAACAAAGACTTCTGCTAGCAAAACTGGAATACCAGGTTCATCGGGATTAGGCAGCCCTCTTGGCCGAAGTCGACATAGTAGTAGTC
AGTCAGACCTGACCAGTTCCAGCAGTAGTTCATCTGGCTTGAGCTTCACTGCATGCATGTCTGACTTTTCCCTTTATGTATTTCATCCAT
ATGGAGCAGGGAAACAAAAAACTGCTGTTTCTGGCCTCACACCTGGATCAGGAGGATTAGGGAATGTGGATGAGGAGCCCACTTCAGTCA
CTGGTCGAAAAGATTCACTCAGTATAAACCTTGAGTTTGTAAAAGTGAGTTTGTCACGGATCAGGCGTTCAGGAGGTGCCTCATTTTTTG
AAAGTCAGTCTGTAAGCAAGTCTGCAAGCAAAATGGATACTACGTTAATAAATATATCTGCTGTTTGTGATATAGGGTCTGCCTCCTTTA
AATATGATATGCGCCGACTCAGTGAAATTCTGGCATTTCCAAGAGCATGGTATAGAAGAAGTATTGCAAGACGTCTATTCCTTGGAGACC
AAACTATAAATTTGCCAACATCTGGCCCAGGGACACCTGATTCCATTGAAGGGGTAAGCCAACACCTTTCCCCTGAATCATCAAGAAAAG
CTTACTGCAAGACCTGGGAGCAGCCAAGTCAGTCAGCCTCCTTCACCCACATGCCTCAGTCACCTAATGTGTTCAATGAGCATATGACAA
ACAGCACCATGTCACCAGGGACAGTAGGACAGAGCCTAAAATCCCCAGCTTCCATAAGATCAAGGAGTGTATCTGATTCTTCAGTTCCTC
GAAGAGATTCACTTTCAAAAACATCAACTCCTTTTAACAAATCAAACAAAGCAGCAAGCCAACAAGGGACCCCATGGGAAACACTTGTCG
TGTTTGCTATCAACTTGAAGCAATTAAACGTTCAAATGAATATGAGTAATGTAATGGGAAATACAACTTGGACAACTAGTGGTTTGAAGA
GCCAGGGCCGTCTGTCAGTAGGAAGTAATCGTGATCGAGAGATCAGCATGTCTGTTGGTCTGGGAAGATCACAATTAGATTCTAAAGGAG
GAGTAGTTGGAGGGACCATAGATGTCAATGCTTTGGAGATGGTTGCTCATATTTCTGAACATCCAAATCAGCAACCCAGTCACAAAATTC
AGATTACTATGGGTTCTACTGAAGCTCGTGTTGATTACATGGGCTCAAGTATCCTCATGGGCATCTTCAGTAATGCTGATCTTAAGCTTC
AGGATGAATGGAAAGTAAACTTGTATAATACATTGGATTCAAGCATAACTGATAAAAGTGAGATTTTCGTCCATGGAGATTTGAAGTGGG
ATATTTTCCAAGTAATGATATCAAGGTCAACCACACCAGATCTGATAAAAATAGGAATGAAGCTCCAGGAATTTTTCACACAACAATTTG
ATACCAGCAAACGAGCTCTGTCTACCTGGGGACCAGTTCCTTACCTTCCGCCAAAGACAATGACTAGCAACCTAGAAAAAAGTTCACAAG
AACAATTACTTGATGCAGCACATCATCGACACTGGCCTGGAGTATTGAAGGTGGTATCAGGATGCCACATATCCTTATTTCAGATTCCAT
TACCAGAAGATGGAATGCAATTTGGAGGATCAATGAGCTTACATGGAAATCATATGACACTGGCATGTTTTCATGGTCCAAATTTTCGTT
CAAAATCTTGGGCCCTTTTTCATTTAGAAGAACCAAATATTGCTTTTTGGACTGAAGCTCAGAAAATCTGGGAAGATGGCTCCAGTGATC
ATTCTACATATATTGTACAAACACTAGATTTTCACCTGGGTCATAATACTATGGTTACCAAACCATGTGGTGCTTTGGAAAGTCCTATGG
CAACAATAACCAAGATAACAAGGCGTCGCCATGAAAATCCACCCCATGGAGTAGCAAGTGTGAAAGAATGGTTCAATTATGTTACAGCTA
CAAGGAATGAAGAGCTAAATCTGCTTCGTAATGTTGATGCTAACAACACTGAGAATAGCACTACTGTGAAGAATTCTAGTTTGTTGAGTG
GATTCAGAGGAGGTTCTAGCTACAACCATGAAACAGAGACTATCTTTGCATTACCAAGGATGCAGCTTGACTTTAAATCCATTCATGTTC
AAGAACCACAGGAGCCTTCATTACAGGATGCCAGCCTGAAGCCAAAAGTAGAATGTAGTGTGGTGACAGAGTTCACTGACCACATTTGTG
TGACTATGGATGCTGAGCTCATCATGTTTCTTCATGATTTAGTATCAGCTTATCTTAAAGAAAAAGAAAAAGCCATCTTTCCACCTCGGA
TTTTATCTACTCGACCAGGACAAAAAAGTCCAATTATTATACATGACGACAATTCCTCTGATAAAGATAGAGAAGATAGCATCACTTATA
CTACTGTGGACTGGAGAGATTTTATGTGCAATACATGGCATCTAGAACCTACTCTTAGATTAATTTCTTGGACTGGAAGAAAGATTGATC
CAGTAGGTGTTGATTATATTCTTCAAAAATTGGGCTTTCATCATGCTAGGACTACTATTCCTAAATGGCTTCAAAGAGGAGTCATGGATC
CACTGGACAAGGTTCTGTCAGTTCTTATCAAAAAGCTCGGTACTGCACTACAGGATGAAAAGGAAAAGAAAGGCAAAGACAAAGAAGAAC
ACTAAAAAAGTAATTTGATCTGTGAACAAATTATGATTGTGTCTGTTTTATTACACTGGAGTGTTTTTTTAGTATAATAATTTGAAATAT
AACTTTAAAATAATTCTAAATTTGTGGCTATAATTAAAAGTTTGTAAGTTAACCTGTTCTAGTTCCATCATTCTGTGTACAGTGAAGTAT
TGCATGATAATGTAAATTTTGTGAAAAACTAGATTAAAATATATAACTGCTTGTTATGGTTTATAATTATATAATGTGCAATACAATTCC
TGCATCTTTAAAATGTCTGCAGAATAACTGTGAATTTTTTTGTTATTGGATTGGCCGTAACTTTTAGAAAAAAATCTTGTTGATGATAAT
GTGATTTTGGGGAGGTCATTAATTGCTTTTTCTTTTTTAAATGTAGACTTATATAAATACCTGTTTGTATATAGCTTGAGTAATTGTGAT
ATGATTGTATACCACTAAAATATTGTTAACTATTATAATAAAGTCACAGTAATGGTTTAA

>10454_10454_1_BTBD2-KIAA1109_BTBD2_chr19_1990002_ENST00000255608_KIAA1109_chr4_123107190_ENST00000264501_length(amino acids)=5215AA_BP=329
MAAGGSGGRASCPPGVGVGPGTGGSPGPSANAAATPAPGNAAAAAAAAAAAAAAPGPTPPAPPGPGTDAQAAGAERAEEAAGPGAAALQR
EAAYNWQASKPTVQERFAFLFNNEVLCDVHFLVGKGLSSQRIPAHRFVLAVGSAVFDAMFNGGMATTSTEIELPDVEPAAFLALLKFLYS
DEVQIGPETVMTTLYTAKKYAVPALEAHCVEFLKKNLRADNAFMLLTQARLFDEPQLASLCLENIDKNTADAITAEGFTDIDLDTLVAVL
ERDTLGIREVRLFNAVVRWSEAECQRQQLQVTPENRRKVLGKALGLIRFPLMTIEEFAADPKAETRLYITVNDFEFHVYNRSDLYGRLQE
LFGLEPTIIPPKKDDDKTREIGRTRTQSKIERVKVKTESQDPTSSWRSLIPVIKVNVSTGRLAFGNHYQPQTLCINFDDAFLTYTTKPPS
SHLDQFMHIVKGKLENVRVMLVPSPRYVGLQNDEPPRLMGEGFVVMQSNDVDIYYYMDEPGLVPEETEENIEGEMSSEDCKLQDLPPCWG
LDIVCGKGTDFNYGPWADRQRDCLWKFFFPPDYQVLKVSEIAQPGRPRQILAFELRMNIIADATIDLLFTKNRETNAVHVNVGAGSYLEI
NIPMTVEENGYTPAIKGQLLHVDATTSMQYRTLLEAEMLAFHINASYPRIWNMPQTWQCELEVYKATYHFIFAQKNFFTDLIQDWSSDSP
PDIFSFVPYTWNFKIMFHQFEMIWAANQHNWIDCSTKQQENVYLAACGETLNIDFSLPFTDFVPATCNTKFSLRGEDVDLHLFLPDCHPS
KYSLFMLVKNCHPNKMIHDTGIPAECQSGQKTVKPKWRNVTQEKSGWVECWTVPSVMLTIDYTWHPIYPQKADEQLKQSLSEMEETMLSV
LRPSQKTSDRVVSSPSTSSRPPIDPSELPPDKLHVEMELSPDSQITLYGPLLNAFLCIKENYFGEDDMYMDFEEVISSPVLSLSTSSSSG
WTAVGMENDKKENEGSAKSIHPLALRPWDITVLVNLYKVHGRLPVHGTTDGPECPTAFLERLCFEMKKGFRETMLQLILSPLNVFVSDNY
QQRPPVDEVLREGHINLSGLQLRAHAMFSAEGLPLGSDSLEYAWLIDVQAGSLTAKVTAPQLACLLEWGQTFVFHVVCREYELERPKSVI
ICQHGIDRRFCESKLSCIPGPCPTSDDLKYTMIRLAVDGADIYIVEHGCATNIKMGAIRVANCNLHNQSVGEGISAAIQDFQVRQYIEQL
NNCRIGLQPAVLRRAYWLEAGSANLGLITVDIALAADHHSKHEAQRHFLETHDARTKRLWFLWPDDILKNKRCRNKCGCLGGCRFFGGTV
TGLDFFKLEELTPSSSSAFSSTSAESDMYYGQSLLQPGEWIITKEIPKIIDGNVNGMKRKEWENKSVGIEVERKTQHLSLQVPLRSHSSS
SSSEENSSSSAAQPLLAGEKESPSSVADDHLVQKEFLHGTKRDDGQASIPTEISGNSPVSPNTQDKSVGQSPLRSPLKRQASVCSTRLGS
TKSLTAAFYGDKQPVTVGVQFSSDVSRSDENVLDSPKQRRSFGSFPYTPSADSNSFHQYRSMDSSMSMADSEAYFSAAEEFEPISSDEGP
GTYPGRKKKKKQTQQIDYSRGSIYHSVEGPLTGHGESIQDSRTLPFKTHPSQASFVSALGGEDDVIEHLYIVEGEKTVESEQITPQQPVM
NCYQTYLTQFQVINWSVKHPTNKRTSKSSLHRPLDLDTPTSEESSSSFEQLSVPTFKVIKQGLTANSLLDRGMQLSGSTSNTPYTPLEKK
LADNTDDETLTEEWTLDQPVSQTRTTAIVEVKGTVDIVLTPLVAEALDRYIEAMVHCASTRHPAAIVDDLHAKVLREAVQNSKTTFSENL
SSKQDIRGTKTEQSTIGTTNQGQAQTNLTMKQDNVTIKGLQTNVSIPKVNLCLLQASVEESPTTAPSRSVTHVSLVALCFDRIATQVRMN
RGVVEETSNNAEPGRTSNFDRYVHATKMQPQSSGSLRSNAGAEKGKEIAAKLNIHRVHGQLRGLDTTDIGTCAITAIPFEKSKVLFTLEE
LDEFTFVDETDQQAVPDVTRIGPSQEKWGWIMFECGLENLTIKGGRQSGAVLYNSFGIMGKASDTERGGVLTSNNSSDSPTGSGYNTDVS
DDNLPCDRTSPSSDLNGNSVSDEQDEGVESDDLKKDLPLMPPPPDSCSMKLTIKEIWFSFAAPTNVRSHTHAFSRQLNLLSTATPAVGAW
LVPIDQLKSSLNKLETEGTLRICAVMGCIMTEALENKSVHFPLRSKYNRLTKVARFLQENPSCLLCNILHHYLHQANYSIIDDATMSDGL
PALVTLKKGLVALARQWMKFIVVTPAFKGVSLHRPAQPLKPQIAMDHEHEDGLGLDNGGGLQSDTSADGAEFEFDAATVSEHTMLLEGTA
NRPPPGSSGPVTGAEIMRKLSKTHTHSDSALKIKGIHPYHSLSYTSGDTATDSPVHVGRAGMPVKDSPRKESLLSYLTGSFPSLHNLLEG
TPQRSSAAVKSSSLTRTGNTVATDMLSEHPLLSEPSSVSFYNWMSNAVGNRGSVLQESPVTKSGHNSLPTGVAPNLPTIPSASDFNTVLS
SDQNTLDGTHSQHSTSQDDVAGVEEANQGFPAVQLADAQVVFKPLLSHTGIQSQDTMPFCYRMYFGEHLSFSGTLDCLRADIVDSDTAKE
RKGKRARRQGHVNLPPLEFKPALMLGTFSISAVVMEKSVCTPQNSTSALSFHDLSKRYYNTFHCNFTISCQSISQHVDMALVRLIHQFST
MIDDIKATQTDIKLSRYTAGSASPTPTFKTRKHRDFRSSDFSRSSRGSLNGGNRVNNAKNKRTNNENNKKESRNKNSLGRSERRTSKVSR
KGSKDVVDHMTIHMDDSDSITVSEQSEPSAECWQNMYKLLNFYSLISDPTGILEKSSETFGPAGVRSPTEPTCKVVFENEQDNSSLTKTQ
RKRSLVTSEPQHVTLIVFGIGMVNRTHLEADIGGLTMESELKRIHGSFTLKEKMKDVLHQKMTETCATAHIGGVNIVLLEGITPNIQLED
FPTSPTSTAKQEFLTVVKCSIAKSQALYSAQRGLKTNNAAVFKVGAISINIPQHPATLHSMMVRSSHQLSKQISDLIRQPSTAPQPVKED
IATPLPSEKTPTSVNQTPVETNEFPQLPEGLEKKPIVLKFSAMLDGIAIGAALLPSLKAEYKMGRMRSHGMTGAQTRFTFELPNHRLRFT
SKVSATDMSTIPPSASLNLPPVTMSGKYIMEEHDSYSDQVWSIDELPSKQGYYLQGNYLRCVAEVGSFEHNLTTDLLNHLVFVQKVFMKE
VNEVIQKVSGGEQPIPLWNEHDGTADGDKPKILLYSLNLQFKGIQVTATTPSMRAVRFETGLIELELSNRLQTKASPGSSSYLKLFGKCQ
VDLNLALGQIVKHQVYEEAGSDFHQVAYFKTRIGLRNALREEISGSSDREAVLITLNRPIVYAQPVAFDRAVLFWLNYKAAYDNWNEQRM
ALHKDIHMATKEVVDMLPGIQQTSAQAFGTLFLQLTVNDLGICLPITNTAQSNHTGDLDTGSALVLTIESTLITACSSESLVSKGHFKNF
CIRFADGFETSWDDWKPEIHGDLVMNACVVPDGTYEVCSRTTGQAAAESSSAGTWTLNVLWKMCGIDVHMDPNIGKRLNALGNTLTTLTG
EEDIDDIADLNSVNIADLSDEDEVDTMSPTIHTEATDYRRQAASASQPGELRGRKIMKRIVDIRELNEQAKVIDDLKKLGASEGTINQEI
QRYQQLESVAVNDIRRDVRKKLRRSSMRAASLKDKWGLSYKPSYSRSKSISASGRPPLKRMERASSRVGETEELPEIRVDAASPGPRVTF
NIQDTFPEETELDLLSVTIEGPSHYSSNSEGSCSVFSSPKTPGGFSPGIPFQTEEGRRDDSLSSTSEDSEKDEKDEDHERERFYIYRKPS
HTSRKKATGFAAVHQLFTERWPTTPVNRSLSGTATERNIDFELDIRVEIDSGKCVLHPTTLLQEHDDISLRRSYDRSSRSLDQDSPSKKK
KFQTNYASTTHLMTGKKVPSSLQTKPSDLETTVFYIPGVDVKLHYNSKTLKTESPNASRGSSLPRTLSKESKLYGMKDSATSPPSPPLPS
TVQSKTNTLLPPQPPPIPAAKGKGSGGVKTAKLYAWVALQSLPEEMVISPCLLDFLEKALETIPITPVERNYTAVSSQDEDMGHFEIPDP
MEESTTSLVSSSTSAYSSFPVDVVVYVRVQPSQIKFSCLPVSRVECMLKLPSLDLVFSSNRGELETLGTTYPAETLSPGGNATQSGTKTS
ASKTGIPGSSGLGSPLGRSRHSSSQSDLTSSSSSSSGLSFTACMSDFSLYVFHPYGAGKQKTAVSGLTPGSGGLGNVDEEPTSVTGRKDS
LSINLEFVKVSLSRIRRSGGASFFESQSVSKSASKMDTTLINISAVCDIGSASFKYDMRRLSEILAFPRAWYRRSIARRLFLGDQTINLP
TSGPGTPDSIEGVSQHLSPESSRKAYCKTWEQPSQSASFTHMPQSPNVFNEHMTNSTMSPGTVGQSLKSPASIRSRSVSDSSVPRRDSLS
KTSTPFNKSNKAASQQGTPWETLVVFAINLKQLNVQMNMSNVMGNTTWTTSGLKSQGRLSVGSNRDREISMSVGLGRSQLDSKGGVVGGT
IDVNALEMVAHISEHPNQQPSHKIQITMGSTEARVDYMGSSILMGIFSNADLKLQDEWKVNLYNTLDSSITDKSEIFVHGDLKWDIFQVM
ISRSTTPDLIKIGMKLQEFFTQQFDTSKRALSTWGPVPYLPPKTMTSNLEKSSQEQLLDAAHHRHWPGVLKVVSGCHISLFQIPLPEDGM
QFGGSMSLHGNHMTLACFHGPNFRSKSWALFHLEEPNIAFWTEAQKIWEDGSSDHSTYIVQTLDFHLGHNTMVTKPCGALESPMATITKI
TRRRHENPPHGVASVKEWFNYVTATRNEELNLLRNVDANNTENSTTVKNSSLLSGFRGGSSYNHETETIFALPRMQLDFKSIHVQEPQEP
SLQDASLKPKVECSVVTEFTDHICVTMDAELIMFLHDLVSAYLKEKEKAIFPPRILSTRPGQKSPIIIHDDNSSDKDREDSITYTTVDWR
DFMCNTWHLEPTLRLISWTGRKIDPVGVDYILQKLGFHHARTTIPKWLQRGVMDPLDKVLSVLIKKLGTALQDEKEKKGKDKEEH

--------------------------------------------------------------
>10454_10454_2_BTBD2-KIAA1109_BTBD2_chr19_1990002_ENST00000255608_KIAA1109_chr4_123107190_ENST00000388738_length(transcript)=16176nt_BP=1005nt
CACGCCGCAGCCACAAAATGGCGGCGGGTGGGAGCGGCGGGCGTGCGTCGTGCCCGCCGGGGGTCGGGGTCGGCCCGGGCACGGGGGGCA
GTCCCGGGCCCAGCGCCAACGCCGCCGCCACCCCGGCCCCCGGCAACGCGGCCGCCGCCGCCGCCGCCGCCGCCGCCGCCGCCGCCGCCC
CTGGGCCGACGCCGCCCGCCCCGCCGGGCCCCGGGACAGACGCGCAGGCCGCGGGCGCGGAGCGGGCGGAGGAGGCGGCGGGCCCGGGGG
CGGCGGCGCTGCAGCGCGAGGCCGCGTACAACTGGCAGGCCAGCAAGCCCACCGTGCAGGAGCGCTTCGCCTTCCTCTTCAACAACGAGG
TGCTGTGCGACGTGCACTTCCTGGTGGGCAAGGGGCTCAGCTCGCAGCGCATCCCCGCGCACAGGTTCGTGCTGGCCGTGGGCAGCGCCG
TCTTTGATGCCATGTTCAACGGGGGAATGGCCACAACATCCACGGAGATTGAGCTGCCCGACGTGGAACCCGCTGCCTTCCTCGCACTGC
TCAAGTTTCTCTACTCGGACGAGGTGCAGATTGGCCCGGAGACGGTGATGACCACGCTATACACCGCCAAGAAGTACGCGGTGCCAGCGC
TCGAGGCCCATTGCGTGGAGTTCCTGAAGAAGAACCTGCGAGCCGACAACGCCTTCATGCTGCTCACGCAGGCGCGACTCTTCGATGAAC
CGCAGCTGGCCAGCCTGTGCCTGGAGAACATCGACAAAAACACTGCAGACGCCATCACCGCGGAGGGCTTCACCGACATTGACCTGGACA
CGCTGGTGGCTGTCCTGGAGCGCGACACACTGGGCATCCGTGAGGTGCGGCTGTTCAATGCCGTTGTCCGCTGGTCCGAGGCCGAGTGTC
AGCGGCAGCAGCTGCAGGTGACGCCAGAGAACAGGCGGAAGGTTCTGGGCAAGGCCCTGGGCCTCATTCGCTTCCCGCTCATGACCATCG
AGGAGTTCGCTGCAGATCCAAAGGCAGAAACCAGGTTATACATCACAGTCAATGACTTTGAATTTCATGTCTATAATCGCTCGGATCTTT
ATGGACGCCTTCAAGAGTTGTTTGGTTTGGAGCCAACAATAATTCCACCTAAGAAAGATGATGATAAAACACGGGAAATTGGAAGAACAA
GAACCCAATCGAAAATTGAAAGAGTTAAAGTAAAAACAGAATCCCAAGACCCCACATCTTCATGGAGATCACTTATTCCAGTCATAAAGG
TCAATGTGAGCACAGGACGTTTGGCCTTTGGAAATCACTACCAGCCGCAAACTCTGTGCATCAACTTTGATGATGCTTTCTTAACTTATA
CTACAAAACCACCTTCAAGTCATCTTGACCAATTCATGCATATTGTGAAAGGAAAGCTTGAAAATGTTCGAGTCATGCTTGTTCCTAGTC
CAAGATATGTTGGTCTTCAAAATGATGAACCACCGAGATTAATGGGAGAAGGTTTTGTGGTGATGCAGTCAAATGATGTTGACATCTACT
ACTACATGGATGAGCCAGGACTTGTTCCGGAAGAAACAGAAGAAAATATTGAAGGAGAAATGAGCAGTGAGGATTGCAAATTACAAGACT
TGCCTCCATGTTGGGGACTGGATATAGTTTGTGGTAAAGGAACAGATTTTAATTATGGACCATGGGCCGATAGGCAGAGAGATTGTTTGT
GGAAGTTTTTCTTTCCACCTGACTATCAAGTTCTGAAAGTTTCTGAAATTGCACAGCCTGGGAGACCAAGACAGATCCTTGCTTTTGAAT
TACGAATGAATATTATTGCAGATGCTACAATTGATTTGCTGTTTACCAAAAATAGGGAAACAAATGCTGTACATGTAAATGTAGGAGCTG
GCTCATATTTAGAAATTAATATTCCAATGACAGTTGAAGAAAATGGTTACACTCCTGCTATTAAGGGACAACTCTTACATGTGGATGCCA
CTACCAGCATGCAATATCGGACCCTTTTAGAAGCAGAAATGTTAGCATTCCACATCAATGCCAGCTACCCCCGAATATGGAACATGCCGC
AGACATGGCAGTGTGAATTAGAGGTTTATAAAGCCACTTACCACTTCATCTTTGCACAGAAAAACTTCTTTACAGATTTAATTCAAGACT
GGTCTAGTGACAGTCCTCCAGACATTTTTTCATTTGTTCCATATACGTGGAATTTTAAAATCATGTTTCATCAGTTTGAAATGATTTGGG
CTGCTAATCAACACAATTGGATCGACTGTTCTACTAAACAACAGGAAAATGTGTATCTGGCAGCCTGTGGAGAAACACTAAACATTGATT
TTTCTTTGCCTTTTACGGACTTTGTTCCAGCTACATGTAATACCAAGTTCTCTTTAAGAGGAGAAGATGTTGATCTTCATTTGTTTCTAC
CAGACTGCCACCCTAGTAAATATTCTTTATTTATGCTGGTAAAAAATTGCCATCCAAATAAGATGATTCATGATACTGGTATTCCTGCTG
AGTGTCAAAGTGGCCAGAAAACAGTTAAACCAAAATGGCGCAACGTTACTCAGGAAAAGTCTGGTTGGGTTGAATGCTGGACTGTCCCAA
GTGTCATGCTTACAATTGATTATACATGGCATCCAATTTATCCACAAAAAGCAGATGAACAGCTGAAACAATCATTATCAGAAATGGAAG
AGACAATGCTATCTGTATTAAGGCCATCCCAGAAGACATCAGACAGAGTTGTTTCTTCTCCCTCTACTTCTTCACGCCCACCTATTGATC
CCTCAGAACTTCCACCTGATAAACTTCATGTAGAAATGGAACTTTCTCCAGATTCTCAGATAACTCTCTATGGACCTCTACTAAATGCCT
TTTTGTGTATAAAGGAAAACTACTTTGGGGAAGATGACATGTATATGGATTTTGAAGAGGTTATCTCAAGTCCTGTTTTGTCACTGTCAA
CATCATCCAGCTCTGGGTGGACTGCTGTTGGAATGGAAAATGACAAAAAGGAAAATGAAGGTTCAGCCAAGTCAATTCATCCACTTGCCT
TGCGTCCTTGGGATATTACTGTACTTGTTAATTTGTACAAAGTTCATGGGCGTCTTCCTGTTCATGGAACTACTGATGGTCCTGAATGCC
CTACAGCTTTCTTGGAAAGACTATGTTTTGAAATGAAAAAAGGATTTAGGGAGACCATGCTGCAACTTATCCTGTCACCCCTGAATGTGT
TTGTCAGTGATAACTATCAGCAGCGACCCCCTGTGGATGAAGTACTCAGGGAAGGTCACATCAATTTGTCAGGTCTCCAGCTGAGAGCAC
ACGCTATGTTCTCAGCAGAAGGTCTTCCTTTGGGAAGCGATTCCTTAGAATACGCATGGTTAATTGATGTGCAGGCTGGAAGTCTTACAG
CTAAGGTCACAGCACCACAGCTGGCATGCCTCTTGGAGTGGGGACAGACATTTGTTTTTCATGTGGTATGTCGGGAGTATGAACTGGAAA
GACCGAAATCAGTTATAATATGTCAGCATGGAATTGATCGTCGGTTCTGTGAATCCAAGTTGAGTTGTATTCCTGGGCCTTGTCCAACTT
CAGATGATTTGAAATATACTATGATTCGTTTAGCAGTAGATGGAGCCGATATTTACATTGTTGAGCATGGTTGTGCTACAAATATAAAGA
TGGGTGCAATTCGAGTTGCAAACTGTAATCTCCACAATCAATCGGTTGGGGAAGGAATCAGTGCTGCAATTCAGGATTTTCAAGTGAGAC
AGTACATTGAGCAATTAAATAATTGCAGAATTGGACTTCAGCCTGCAGTGCTACGGAGGGCCTATTGGCTTGAAGCTGGGTCAGCCAATT
TAGGACTTATTACTGTTGATATTGCTTTAGCTGCTGACCATCATTCTAAACATGAGGCACAAAGACATTTCTTAGAAACTCATGATGCCA
GAACTAAGAGGTTGTGGTTTTTATGGCCAGATGATATCCTGAAGAATAAGAGGTGTAGAAACAAATGTGGTTGTCTCGGTGGCTGCAGAT
TCTTTGGTGGCACAGTAACTGGCCTAGATTTCTTCAAACTTGAAGAGTTGACACCTTCCAGTAGCTCTGCATTTTCAAGCACAAGTGCAG
AGTCTGATATGTATTATGGACAGTCTCTGCTACAGCCTGGAGAATGGATAATTACTAAAGAAATTCCCAAAATTATAGATGGTAATGTGA
ATGGCATGAAGAGGAAAGAATGGGAAAACAAATCAGTGGGAATAGAAGTAGAGAGAAAAACTCAGCACCTTAGTCTTCAAGTACCATTAC
GATCTCATAGTTCATCCTCTTCCTCAGAAGAGAACAGTAGTTCTAGTGCTGCACAGCCTTTGTTGGCTGGTGAAAAGGAAAGTCCTTCAT
CTGTTGCTGATGACCATTTGGTTCAAAAAGAGTTCTTGCATGGGACAAAAAGAGATGATGGCCAAGCAAGTATCCCTACAGAAATTTCAG
GAAACAGCCCTGTGTCTCCTAATACTCAGGATAAGTCAGTAGGTCAATCTCCTCTTAGATCTCCCTTGAAACGACAAGCCTCTGTCTGTT
CCACCCGTCTTGGAAGTACTAAGAGTCTTACTGCTGCTTTCTATGGGGACAAGCAGCCTGTAACAGTTGGAGTCCAGTTTAGTAGTGATG
TCTCTCGAAGTGATGAGAATGTACTAGACTCACCAAAGCAGAGGAGAAGTTTTGGTTCATTCCCATATACACCATCAGCAGACTCTAATT
CATTTCATCAGTATCGATCAATGGATTCCAGCATGTCAATGGCTGATAGTGAAGCCTACTTTTCTGCTGCTGAGGAATTTGAGCCCATTA
GCAGTGATGAAGGCCCTGGAACTTATCCGGGTAGAAAAAAGAAGAAAAAGCAAACCCAGCAGATTGACTACAGTAGGGGTTCCATATATC
ACAGTGTAGAAGGGCCACTTACTGGACATGGAGAAAGCATTCAGGATTCCAGAACTCTGCCATTCAAAACTCATCCTTCTCAGGCTTCAT
TTGTTTCTGCGTTAGGTGGAGAAGATGATGTTATAGAACATCTATATATTGTAGAAGGTGAGAAAACAGTGGAGAGTGAACAGATTACTC
CGCAACAACCCGTGATGAATTGTTATCAGACTTACCTTACTCAGTTCCAGGTAATTAATTGGTCAGTTAAGCACCCAACCAACAAAAGAA
CCTCTAAATCCTCATTGCATCGTCCCCTTGATCTGGATACACCAACCAGTGAAGAAAGTTCATCGTCATTTGAACAGCTTTCTGTTCCAA
CTTTTAAGGTTATCAAGCAGGGGCTCACAGCTAATTCTTTGCTAGACAGAGGCATGCAACTTTCAGGATCAACTTCAAATACGCCGTATA
CTCCATTGGAAAAAAAACTCGCTGATAACACAGATGATGAAACATTAACAGAAGAGTGGACCCTGGATCAACCAGTGTCCCAGACCAGGA
CAACAGCCATAGTTGAAGTAAAAGGAACTGTTGATATTGTTTTGACTCCCCTGGTGGCTGAAGCTTTAGACAGATATATTGAAGCAATGG
TTCATTGTGCTAGTACCCGACATCCAGCTGCAATTGTAGATGATCTTCATGCTAAAGTCCTCAGGGAAGCTGTCCAAAATAGCAAGACTA
CCTTTTCAGAAAATTTATCTTCCAAACAAGACATTAGAGGAACAAAAACTGAGCAGTCTACAATAGGAACGACTAACCAAGGACAAGCAC
AGACAAATCTTACAATGAAGCAAGATAATGTAACAATTAAAGGTCTTCAGACTAATGTTAGCATACCAAAGGTAAACTTATGTTTGTTAC
AAGCCTCAGTGGAAGAATCTCCAACTACGGCTCCTAGTAGGAGTGTGACTCATGTTTCCCTAGTGGCATTGTGTTTTGACAGAATTGCTA
CACAGGTTCGCATGAACAGAGGTGTGGTTGAAGAGACTTCAAACAATGCAGAACCTGGTAGAACATCAAATTTTGATAGGTATGTTCATG
CCACAAAGATGCAGCCTCAGTCATCTGGATCTCTCAGATCAAATGCTGGAGCAGAAAAAGGCAAAGAAATTGCAGCTAAGTTAAACATTC
ATCGAGTTCATGGGCAACTTAGGGGTCTTGATACAACAGACATTGGGACCTGTGCAATCACTGCTATTCCTTTTGAGAAGTCCAAAGTTT
TATTTACTCTTGAAGAGTTGGATGAATTTACTTTTGTGGATGAAACTGATCAGCAAGCTGTTCCAGATGTAACTCGAATAGGTCCCAGCC
AAGAAAAATGGGGATGGATAATGTTTGAATGTGGACTTGAAAATTTAACCATAAAAGGAGGAAGACAGTCTGGTGCTGTTTTATATAACA
GTTTTGGAATTATGGGTAAAGCTAGTGACACAGAAAGGGGTGGAGTGCTGACATCCAATAATTCTTCTGATTCTCCAACCGGCAGTGGCT
ATAATACTGATGTCTCTGATGATAATCTTCCATGTGACCGGACAAGCCCTTCCTCAGACTTAAATGGAAATTCTGTTTCAGATGAACAGG
ATGAAGGAGTCGAATCTGATGATTTGAAAAAAGATCTACCTCTGATGCCTCCTCCTCCAGATTCATGTAGCATGAAGTTGACCATTAAAG
AAATTTGGTTTAGTTTTGCAGCTCCCACCAATGTGAGATCTCACACACATGCATTTTCTAGGCAGCTGAACCTTTTAAGCACTGCAACAC
CAGCTGTTGGTGCATGGCTTGTTCCCATTGACCAACTCAAGTCATCTTTAAACAAATTGGAAACTGAGGGAACCTTGAGAATTTGTGCTG
TTATGGGATGCATAATGACAGAAGCATTAGAGAATAAAAGTGTACATTTTCCCCTAAGAAGTAAATACAACAGGCTTACAAAAGTTGCTC
GCTTTCTCCAAGAAAATCCTTCATGTTTACTATGTAATATACTACACCACTATCTGCACCAGGCAAATTACTCCATCATTGATGATGCTA
CAATGAGCGATGGACTTCCTGCTTTGGTAACTTTGAAGAAAGGTTTAGTTGCACTGGCAAGGCAGTGGATGAAGTTTATTGTGGTGACAC
CAGCCTTTAAAGGAGTTAGCTTACATAGACCAGCTCAGCCTCTGAAACCTCAAATAGCTATGGACCATGAACATGAAGATGGACTTGGAT
TGGACAATGGGGGTGGTCTTCAAAGTGATACCAGTGCTGATGGAGCAGAATTTGAGTTCGATGCAGCCACAGTCAGTGAACACACAATGC
TATTAGAAGGAACAGCTAACCGGCCTCCACCTGGTAGCTCTGGACCTGTAACTGGAGCTGAGATAATGAGGAAACTTTCTAAAACTCATA
CCCATAGTGACTCTGCATTAAAAATAAAGGGCATTCACCCATATCATTCTCTGAGCTATACCAGTGGAGACACTGCCACTGATTCTCCAG
TGCATGTTGGACGTGCTGGGATGCCAGTAAAGGACAGTCCAAGGAAGGAGAGCCTACTCAGCTACCTGACTGGAAGCTTCCCAAGCCTGC
ACAACCTCCTGGAAGGTACTCCTCAGAGAAGCAGTGCTGCTGTGAAAAGTAGCTCCCTAACGAGAACAGGAAATACAGTAGCCACTGATA
TGTTATCTGAACATCCCTTGCTATCTGAGCCATCATCTGTGAGTTTCTATAATTGGATGTCAAATGCTGTGGGTAATCGAGGAAGTGTGT
TACAAGAATCTCCTGTTACAAAATCAGGACACAATAGTCTTCCCACAGGTGTTGCACCCAATCTTCCAACAATACCCTCAGCCTCAGATT
TCAACACTGTCTTGTCTAGTGACCAAAATACTTTGGATGGGACACATTCTCAGCATAGCACCAGTCAGGATGATGTGGCAGGTGTAGAAG
AAGCAAACCAAGGGTTTCCTGCTGTTCAGCTTGCTGATGCACAGGTTGTTTTCAAGCCTCTTCTGAGTCATACAGGGATCCAGTCACAGG
ATACAATGCCATTCTGCTACCGAATGTACTTTGGAGAACACCTTTCATTTTCAGGGACTTTGGACTGCCTCAGAGCAGATATTGTGGATT
CAGACACAGCCAAAGAGAGAAAAGGCAAAAGAGCAAGAAGGCAAGGCCATGTGAATCTTCCTCCACTTGAGTTCAAACCAGCATTAATGT
TGGGAACCTTTAGCATCAGTGCTGTTGTAATGGAAAAGTCCGTGTGCACCCCTCAGAACTCTACCAGTGCCCTTTCTTTTCATGATCTCA
GCAAGCGGTATTATAACACCTTTCACTGCAACTTTACTATTTCCTGTCAGTCAATAAGCCAGCATGTAGATATGGCTTTGGTTCGTCTTA
TTCATCAGTTTAGCACAATGATAGATGACATCAAAGCAACTCAGACTGATATTAAACTTAGCAGATATACAGCCGGATCTGCTTCCCCAA
CACCTACCTTCAAAACCAGAAAACATCGGGACTTTCGTTCATCTGACTTTAGCCGCAGTTCTAGAGGAAGTCTTAATGGTGGCAATAGAG
TAAATAATGCAAAGAACAAACGGACCAACAATGAGAATAACAAAAAGGAATCTCGAAACAAGAATTCATTAGGAAGATCTGAAAGAAGAA
CATCAAAAGTGTCTAGGAAAGGTTCAAAAGATGTGGTGGATCACATGACTATTCATATGGATGACTCTGATTCAATTACAGTGTCAGAAC
AAAGTGAGCCTTCAGCTGAGTGCTGGCAGAATATGTATAAATTGCTTAACTTCTATTCACTTATCTCCGATCCAACAGGAATATTGGAAA
AGTCTTCAGAAACATTTGGACCAGCAGGAGTTCGGAGCCCTACAGAGCCAACATGTAAAGTTGTGTTTGAGAATGAACAAGACAACAGCA
GTTTGACTAAGACTCAGAGGAAACGTAGCTTGGTAACTTCTGAACCTCAGCATGTTACTCTAATAGTGTTTGGGATTGGCATGGTGAACC
GCACACACCTAGAGGCAGATATTGGTGGACTAACAATGGAATCAGAACTGAAGAGGATCCATGGCAGTTTTACTCTTAAGGAAAAAATGA
AAGATGTTTTACATCAAAAGATGACTGAGACTTGTGCTACTGCTCATATTGGTGGGGTTAATATTGTGCTGCTTGAAGGGATTACACCAA
ATATACAACTGGAGGATTTTCCTACATCTCCTACAAGTACAGCCAAACAAGAGTTTCTAACTGTAGTGAAATGTAGTATTGCCAAGTCCC
AAGCCCTCTACAGTGCCCAAAGAGGGCTGAAGACAAACAATGCTGCTGTGTTCAAAGTAGGAGCTATCAGTATCAACATTCCTCAGCACC
CTGCCACCTTACATAGCATGATGGTTCGAAGTTCTCACCAACTATCTAAACAAATCTCAGACCTAATCAGACAGCCTTCTACAGCCCCAC
AGCCTGTAAAAGAAGATATTGCAACCCCACTACCTTCTGAAAAAACCCCAACAAGTGTTAATCAAACTCCTGTTGAAACAAATGAATTTC
CTCAGCTACCAGAAGGCTTAGAAAAGAAGCCTATTGTTCTTAAATTCAGTGCCATGTTAGATGGTATAGCCATTGGAGCAGCACTTTTAC
CATCTCTGAAAGCAGAATACAAGATGGGAAGAATGAGAAGTCATGGAATGACAGGTGCACAGACAAGATTTACATTTGAGCTGCCAAATC
ACAGATTGCGTTTTACTTCAAAAGTTTCTGCCACAGATATGTCAACCATTCCTCCTTCTGCCAGTCTTAACCTTCCCCCTGTTACCATGT
CAGGGAAATATATAATGGAAGAACATGATAGTTATTCGGATCAGGTGTGGAGTATAGATGAACTGCCTTCTAAACAAGGTTACTATTTAC
AGGGAAATTATCTGCGTTGTGTGGCAGAAGTTGGTTCCTTTGAACATAATCTTACAACTGATCTTCTAAACCACTTGGTATTTGTACAGA
AAGTGTTCATGAAGGAAGTTAATGAAGTAATACAAAAAGTTTCTGGTGGGGAGCAGCCTATTCCTCTCTGGAACGAACATGATGGAACAG
CAGATGGAGATAAACCTAAAATTCTCCTCTATTCCCTAAACTTGCAGTTCAAGGGTATTCAAGTAACGGCCACTACTCCATCAATGAGAG
CTGTAAGATTTGAAACTGGATTGATTGAACTGGAACTTTCTAACCGACTTCAAACCAAAGCTTCACCAGGAAGTAGCAGCTATCTGAAAC
TGTTTGGCAAATGCCAGGTGGATTTAAATCTGGCATTAGGACAAATTGTCAAACATCAGGTTTATGAGGAAGCTGGTTCTGATTTTCATC
AAGTTGCCTATTTTAAAACCAGAATTGGATTAAGAAATGCCCTCCGAGAAGAAATCAGTGGTTCTTCAGATAGGGAAGCTGTGCTTATTA
CTTTGAATAGACCAATTGTTTATGCACAGCCTGTGGCCTTTGATAGAGCTGTGCTGTTTTGGCTGAATTATAAGGCCGCCTATGACAACT
GGAATGAACAACGAATGGCTTTACATAAGGATATTCATATGGCTACAAAGGAAGTAGTAGATATGCTACCTGGTATCCAGCAAACATCAG
CCCAGGCCTTTGGGACTCTTTTTCTCCAGCTCACTGTCAATGATCTGGGAATTTGCCTACCTATCACAAATACTGCACAGTCTAATCATA
CTGGAGACCTTGACACTGGTTCTGCTTTGGTATTAACCATTGAAAGTACTCTCATCACTGCATGCTCTTCAGAGTCTCTGGTTAGCAAAG
GGCATTTCAAAAACTTTTGTATCCGTTTTGCTGATGGATTTGAGACATCATGGGATGACTGGAAACCAGAAATTCATGGGGATTTAGTGA
TGAATGCCTGTGTAGTTCCAGATGGCACCTATGAAGTATGTTCAAGAACTACAGGACAAGCAGCAGCTGAAAGCAGTAGTGCTGGAACCT
GGACACTCAACGTATTGTGGAAAATGTGTGGGATTGATGTTCACATGGATCCTAACATTGGCAAAAGGCTTAATGCTCTGGGCAATACTC
TTACAACACTGACAGGAGAGGAAGACATAGATGACATTGCTGACTTAAATTCAGTGAACATAGCTGACCTGTCAGATGAGGATGAAGTTG
ATACTATGTCTCCCACTATCCATACTGAAGCCACAGATTATCGAAGACAGGCAGCATCTGCTAGCCAGCCGGGAGAACTTAGAGGAAGAA
AAATTATGAAGCGTATAGTGGATATCAGAGAACTGAATGAACAGGCCAAAGTAATAGATGATCTGAAAAAATTAGGTGCAAGTGAAGGAA
CCATAAACCAGGAAATTCAACGTTACCAACAGTTAGAATCTGTGGCTGTGAATGACATTAGAAGAGATGTTCGTAAAAAATTACGGAGGT
CCAGTATGCGGGCTGCTTCCCTAAAGGATAAGTGGGGTTTGAGTTACAAACCAAGTTACAGCCGATCAAAAAGCATTTCTGCTTCTGGAA
GACCACCTCTTAAGCGAATGGAAAGGGCAAGTTCTCGAGTAGGAGAAACTGAAGAGCTCCCAGAAATCCGTGTGGATGCAGCATCTCCTG
GACCTAGAGTAACTTTTAATATCCAGGATACATTTCCAGAGGAGACAGAACTGGACCTTTTGTCAGTAACCATTGAAGGTCCATCCCATT
ATTCATCAAATAGTGAAGGATCATGTTCTGTGTTCAGTTCTCCCAAAACTCCAGGAGGCTTTTCACCAGGCATTCCTTTCCAAACTGAAG
AGGGCCGACGGGATGACAGTTTGTCTTCTACCAGTGAAGATTCCGAGAAGGATGAAAAAGATGAAGACCATGAGAGGGAAAGGTTTTATA
TTTACAGGAAACCCTCACATACGTCTCGTAAAAAAGCAACAGGCTTTGCTGCTGTTCATCAGCTATTTACAGAACGCTGGCCAACAACAC
CAGTCAATAGAAGTCTTAGTGGCACAGCTACAGAGAGAAATATTGACTTTGAACTTGATATACGGGTTGAAATTGATAGTGGAAAATGTG
TACTCCACCCAACCACCCTTCTACAAGAACATGATGATATAAGTTTGAGAAGGAGTTATGATCGAAGTTCCAGGAGCTTAGATCAAGATT
CACCTTCAAAAAAGAAGAAGTTTCAAACTAATTATGCTTCTACCACCCATTTAATGACCGGCAAGAAAGTGCCATCATCTCTACAGACAA
AGCCTAGTGACTTAGAAACAACAGTATTTTACATTCCCGGAGTTGATGTAAAGTTGCATTACAATTCCAAGACGCTAAAGACTGAATCAC
CTAATGCCTCCAGGGGATCTTCCTTGCCAAGAACACTGTCCAAAGAGTCCAAGCTGTATGGTATGAAAGATAGTGCAACATCTCCTCCTT
CTCCTCCTTTACCTTCCACTGTCCAGAGCAAGACTAACACCTTACTTCCTCCCCAGCCCCCACCTATTCCTGCAGCCAAAGGAAAAGGAA
GTGGAGGAGTAAAAACAGCCAAGTTATATGCCTGGGTAGCACTTCAGTCATTGCCAGAAGAAATGGTTATTAGTCCCTGCCTATTAGACT
TTCTGGAAAAAGCTCTGGAAACTATCCCAATTACACCAGTTGAAAGGAATTATACAGCTGTCAGCTCACAAGATGAAGATATGGGACATT
TTGAAATACCAGATCCTATGGAAGAATCAACAACATCACTAGTGTCGTCTTCAACATCTGCTTACTCTTCCTTCCCTGTAGATGTTGTGG
TTTATGTACGAGTTCAGCCCTCACAGATCAAATTTAGCTGTTTACCAGTATCAAGAGTAGAATGCATGTTAAAGCTGCCATCCCTGGATT
TGGTGTTTTCTTCAAACCGAGGAGAACTGGAGACTTTAGGGACTACATATCCTGCAGAGACTTTATCCCCTGGAGGTAATGCTACTCAGA
GTGGAACAAAGACTTCTGCTAGCAAAACTGGAATACCAGGTTCATCGGGATTAGGCAGCCCTCTTGGCCGAAGTCGACATAGTAGTAGTC
AGTCAGACCTGACCAGTTCCAGCAGTAGTTCATCTGGCTTGAGCTTCACTGCATGCATGTCTGACTTTTCCCTTTATGTATTTCATCCAT
ATGGAGCAGGGAAACAAAAAACTGCTGTTTCTGGCCTCACACCTGGATCAGGAGGATTAGGGAATGTGGATGAGGAGCCCACTTCAGTCA
CTGGTCGAAAAGATTCACTCAGTATAAACCTTGAGTTTGTAAAAGTGAGTTTGTCACGGATCAGGCGTTCAGGAGGTGCCTCATTTTTTG
AAAGTCAGTCTGTAAGCAAGTCTGCAAGCAAAATGGATACTACGTTAATAAATATATCTGCTGTTTGTGATATAGGGTCTGCCTCCTTTA
AATATGATATGCGCCGACTCAGTGAAATTCTGGCATTTCCAAGAGCATGGTATAGAAGAAGTATTGCAAGACGTCTATTCCTTGGAGACC
AAACTATAAATTTGCCAACATCTGGCCCAGGGACACCTGATTCCATTGAAGGGGTAAGCCAACACCTTTCCCCTGAATCATCAAGAAAAG
CTTACTGCAAGACCTGGGAGCAGCCAAGTCAGTCAGCCTCCTTCACCCACATGCCTCAGTCACCTAATGTGTTCAATGAGCATATGACAA
ACAGCACCATGTCACCAGGGACAGTAGGACAGAGCCTAAAATCCCCAGCTTCCATAAGATCAAGGAGTGTATCTGATTCTTCAGTTCCTC
GAAGAGATTCACTTTCAAAAACATCAACTCCTTTTAACAAATCAAACAAAGCAGCAAGCCAACAAGGGACCCCATGGGAAACACTTGTCG
TGTTTGCTATCAACTTGAAGCAATTAAACGTTCAAATGAATATGAGTAATGTAATGGGAAATACAACTTGGACAACTAGTGGTTTGAAGA
GCCAGGGCCGTCTGTCAGTAGGAAGTAATCGTGATCGAGAGATCAGCATGTCTGTTGGTCTGGGAAGATCACAATTAGATTCTAAAGGAG
GAGTAGTTGGAGGGACCATAGATGTCAATGCTTTGGAGATGGTTGCTCATATTTCTGAACATCCAAATCAGCAACCCAGTCACAAAATTC
AGATTACTATGGGTTCTACTGAAGCTCGTGTTGATTACATGGGCTCAAGTATCCTCATGGGCATCTTCAGTAATGCTGATCTTAAGCTTC
AGGATGAATGGAAAGTAAACTTGTATAATACATTGGATTCAAGCATAACTGATAAAAGTGAGATTTTCGTCCATGGAGATTTGAAGTGGG
ATATTTTCCAAGTAATGATATCAAGGTCAACCACACCAGATCTGATAAAAATAGGAATGAAGCTCCAGGAATTTTTCACACAACAATTTG
ATACCAGCAAACGAGCTCTGTCTACCTGGGGACCAGTTCCTTACCTTCCGCCAAAGACAATGACTAGCAACCTAGAAAAAAGTTCACAAG
AACAATTACTTGATGCAGCACATCATCGACACTGGCCTGGAGTATTGAAGGTGGTATCAGGATGCCACATATCCTTATTTCAGATTCCAT
TACCAGAAGATGGAATGCAATTTGGAGGATCAATGAGCTTACATGGAAATCATATGACACTGGCATGTTTTCATGGTCCAAATTTTCGTT
CAAAATCTTGGGCCCTTTTTCATTTAGAAGAACCAAATATTGCTTTTTGGACTGAAGCTCAGAAAATCTGGGAAGATGGCTCCAGTGATC
ATTCTACATATATTGTACAAACACTAGATTTTCACCTGGGTCATAATACTATGGTTACCAAACCATGTGGTGCTTTGGAAAGTCCTATGG
CAACAATAACCAAGATAACAAGGCGTCGCCATGAAAATCCACCCCATGGAGTAGCAAGTGTGAAAGAATGGTTCAATTATGTTACAGCTA
CAAGGAATGAAGAGCTAAATCTGCTTCGTAATGTTGATGCTAACAACACTGAGAATAGCACTACTGTGAAGAATTCTAGTTTGTTGAGTG
GATTCAGAGGAGGTTCTAGCTACAACCATGAAACAGAGACTATCTTTGCATTACCAAGGATGCAGCTTGACTTTAAATCCATTCATGTTC
AAGAACCACAGGAGCCTTCATTACAGGATGCCAGCCTGAAGCCAAAAGTAGAATGTAGTGTGGTGACAGAGTTCACTGACCACATTTGTG
TGACTATGGATGCTGAGCTCATCATGTTTCTTCATGATTTAGTATCAGCTTATCTTAAAGAAAAAGAAAAAGCCATCTTTCCACCTCGGA
TTTTATCTACTCGACCAGGACAAAAAAGTCCAATTATTATACATGACGACAATTCCTCTGATAAAGATAGAGAAGATAGCATCACTTATA
CTACTGTGGACTGGAGAGATTTTATGTGCAATACATGGCATCTAGAACCTACTCTTAGATTAATTTCTTGGACTGGAAGAAAGATTGATC
CAGTAGGTGTTGATTATATTCTTCAAAAATTGGGCTTTCATCATGCTAGGACTACTATTCCTAAATGGCTTCAAAGAGGAGTCATGGATC
CACTGGACAAGGTTCTGTCAGTTCTTATCAAAAAGCTCGGTACTGCACTACAGGATGAAAAGGAAAAGAAAGGCAAAGACAAAGAAGAAC
ACTAAAAAAGTAATTTGATCTGTGAACAAATTATGATTGTGTCTGTTTTATTACACTGGAGTGTTTTTTTAGTATAATAATTTGAAATAT
AACTTTAAAATAATTCTAAATTTGTGGCTATAATTAAAAGTTTGTAAGTTAACCTGTTCTAGTTCCATCATTCTGTGTACAGTGAAGTAT
TGCATGATAATGTAAATTTTGTGAAAAACTAGATTAAAATATATAACTGCTTGTTATGGTTTATAATTATATAATGTGCAATACAATTCC
TGCATCTTTAAAATGTCTGCAGAATAACTGTGAATTTTTTTGTTATTGGATTGGCCGTAACTTTTAGAAAAAAATCTTGTTGATGATAAT
GTGATTTTGGGGAGGTCATTAATTGCTTTTTCTTTTTTAAATGTAGACTTATATAAATACCTGTTTGTATATAGCTTGAGTAATTGTGAT
ATGATTGTATACCACTAAAATATTGTTAACTATTATAATAAAGTCACAGTAATGGTTTAAGTCTGT

>10454_10454_2_BTBD2-KIAA1109_BTBD2_chr19_1990002_ENST00000255608_KIAA1109_chr4_123107190_ENST00000388738_length(amino acids)=5215AA_BP=329
MAAGGSGGRASCPPGVGVGPGTGGSPGPSANAAATPAPGNAAAAAAAAAAAAAAPGPTPPAPPGPGTDAQAAGAERAEEAAGPGAAALQR
EAAYNWQASKPTVQERFAFLFNNEVLCDVHFLVGKGLSSQRIPAHRFVLAVGSAVFDAMFNGGMATTSTEIELPDVEPAAFLALLKFLYS
DEVQIGPETVMTTLYTAKKYAVPALEAHCVEFLKKNLRADNAFMLLTQARLFDEPQLASLCLENIDKNTADAITAEGFTDIDLDTLVAVL
ERDTLGIREVRLFNAVVRWSEAECQRQQLQVTPENRRKVLGKALGLIRFPLMTIEEFAADPKAETRLYITVNDFEFHVYNRSDLYGRLQE
LFGLEPTIIPPKKDDDKTREIGRTRTQSKIERVKVKTESQDPTSSWRSLIPVIKVNVSTGRLAFGNHYQPQTLCINFDDAFLTYTTKPPS
SHLDQFMHIVKGKLENVRVMLVPSPRYVGLQNDEPPRLMGEGFVVMQSNDVDIYYYMDEPGLVPEETEENIEGEMSSEDCKLQDLPPCWG
LDIVCGKGTDFNYGPWADRQRDCLWKFFFPPDYQVLKVSEIAQPGRPRQILAFELRMNIIADATIDLLFTKNRETNAVHVNVGAGSYLEI
NIPMTVEENGYTPAIKGQLLHVDATTSMQYRTLLEAEMLAFHINASYPRIWNMPQTWQCELEVYKATYHFIFAQKNFFTDLIQDWSSDSP
PDIFSFVPYTWNFKIMFHQFEMIWAANQHNWIDCSTKQQENVYLAACGETLNIDFSLPFTDFVPATCNTKFSLRGEDVDLHLFLPDCHPS
KYSLFMLVKNCHPNKMIHDTGIPAECQSGQKTVKPKWRNVTQEKSGWVECWTVPSVMLTIDYTWHPIYPQKADEQLKQSLSEMEETMLSV
LRPSQKTSDRVVSSPSTSSRPPIDPSELPPDKLHVEMELSPDSQITLYGPLLNAFLCIKENYFGEDDMYMDFEEVISSPVLSLSTSSSSG
WTAVGMENDKKENEGSAKSIHPLALRPWDITVLVNLYKVHGRLPVHGTTDGPECPTAFLERLCFEMKKGFRETMLQLILSPLNVFVSDNY
QQRPPVDEVLREGHINLSGLQLRAHAMFSAEGLPLGSDSLEYAWLIDVQAGSLTAKVTAPQLACLLEWGQTFVFHVVCREYELERPKSVI
ICQHGIDRRFCESKLSCIPGPCPTSDDLKYTMIRLAVDGADIYIVEHGCATNIKMGAIRVANCNLHNQSVGEGISAAIQDFQVRQYIEQL
NNCRIGLQPAVLRRAYWLEAGSANLGLITVDIALAADHHSKHEAQRHFLETHDARTKRLWFLWPDDILKNKRCRNKCGCLGGCRFFGGTV
TGLDFFKLEELTPSSSSAFSSTSAESDMYYGQSLLQPGEWIITKEIPKIIDGNVNGMKRKEWENKSVGIEVERKTQHLSLQVPLRSHSSS
SSSEENSSSSAAQPLLAGEKESPSSVADDHLVQKEFLHGTKRDDGQASIPTEISGNSPVSPNTQDKSVGQSPLRSPLKRQASVCSTRLGS
TKSLTAAFYGDKQPVTVGVQFSSDVSRSDENVLDSPKQRRSFGSFPYTPSADSNSFHQYRSMDSSMSMADSEAYFSAAEEFEPISSDEGP
GTYPGRKKKKKQTQQIDYSRGSIYHSVEGPLTGHGESIQDSRTLPFKTHPSQASFVSALGGEDDVIEHLYIVEGEKTVESEQITPQQPVM
NCYQTYLTQFQVINWSVKHPTNKRTSKSSLHRPLDLDTPTSEESSSSFEQLSVPTFKVIKQGLTANSLLDRGMQLSGSTSNTPYTPLEKK
LADNTDDETLTEEWTLDQPVSQTRTTAIVEVKGTVDIVLTPLVAEALDRYIEAMVHCASTRHPAAIVDDLHAKVLREAVQNSKTTFSENL
SSKQDIRGTKTEQSTIGTTNQGQAQTNLTMKQDNVTIKGLQTNVSIPKVNLCLLQASVEESPTTAPSRSVTHVSLVALCFDRIATQVRMN
RGVVEETSNNAEPGRTSNFDRYVHATKMQPQSSGSLRSNAGAEKGKEIAAKLNIHRVHGQLRGLDTTDIGTCAITAIPFEKSKVLFTLEE
LDEFTFVDETDQQAVPDVTRIGPSQEKWGWIMFECGLENLTIKGGRQSGAVLYNSFGIMGKASDTERGGVLTSNNSSDSPTGSGYNTDVS
DDNLPCDRTSPSSDLNGNSVSDEQDEGVESDDLKKDLPLMPPPPDSCSMKLTIKEIWFSFAAPTNVRSHTHAFSRQLNLLSTATPAVGAW
LVPIDQLKSSLNKLETEGTLRICAVMGCIMTEALENKSVHFPLRSKYNRLTKVARFLQENPSCLLCNILHHYLHQANYSIIDDATMSDGL
PALVTLKKGLVALARQWMKFIVVTPAFKGVSLHRPAQPLKPQIAMDHEHEDGLGLDNGGGLQSDTSADGAEFEFDAATVSEHTMLLEGTA
NRPPPGSSGPVTGAEIMRKLSKTHTHSDSALKIKGIHPYHSLSYTSGDTATDSPVHVGRAGMPVKDSPRKESLLSYLTGSFPSLHNLLEG
TPQRSSAAVKSSSLTRTGNTVATDMLSEHPLLSEPSSVSFYNWMSNAVGNRGSVLQESPVTKSGHNSLPTGVAPNLPTIPSASDFNTVLS
SDQNTLDGTHSQHSTSQDDVAGVEEANQGFPAVQLADAQVVFKPLLSHTGIQSQDTMPFCYRMYFGEHLSFSGTLDCLRADIVDSDTAKE
RKGKRARRQGHVNLPPLEFKPALMLGTFSISAVVMEKSVCTPQNSTSALSFHDLSKRYYNTFHCNFTISCQSISQHVDMALVRLIHQFST
MIDDIKATQTDIKLSRYTAGSASPTPTFKTRKHRDFRSSDFSRSSRGSLNGGNRVNNAKNKRTNNENNKKESRNKNSLGRSERRTSKVSR
KGSKDVVDHMTIHMDDSDSITVSEQSEPSAECWQNMYKLLNFYSLISDPTGILEKSSETFGPAGVRSPTEPTCKVVFENEQDNSSLTKTQ
RKRSLVTSEPQHVTLIVFGIGMVNRTHLEADIGGLTMESELKRIHGSFTLKEKMKDVLHQKMTETCATAHIGGVNIVLLEGITPNIQLED
FPTSPTSTAKQEFLTVVKCSIAKSQALYSAQRGLKTNNAAVFKVGAISINIPQHPATLHSMMVRSSHQLSKQISDLIRQPSTAPQPVKED
IATPLPSEKTPTSVNQTPVETNEFPQLPEGLEKKPIVLKFSAMLDGIAIGAALLPSLKAEYKMGRMRSHGMTGAQTRFTFELPNHRLRFT
SKVSATDMSTIPPSASLNLPPVTMSGKYIMEEHDSYSDQVWSIDELPSKQGYYLQGNYLRCVAEVGSFEHNLTTDLLNHLVFVQKVFMKE
VNEVIQKVSGGEQPIPLWNEHDGTADGDKPKILLYSLNLQFKGIQVTATTPSMRAVRFETGLIELELSNRLQTKASPGSSSYLKLFGKCQ
VDLNLALGQIVKHQVYEEAGSDFHQVAYFKTRIGLRNALREEISGSSDREAVLITLNRPIVYAQPVAFDRAVLFWLNYKAAYDNWNEQRM
ALHKDIHMATKEVVDMLPGIQQTSAQAFGTLFLQLTVNDLGICLPITNTAQSNHTGDLDTGSALVLTIESTLITACSSESLVSKGHFKNF
CIRFADGFETSWDDWKPEIHGDLVMNACVVPDGTYEVCSRTTGQAAAESSSAGTWTLNVLWKMCGIDVHMDPNIGKRLNALGNTLTTLTG
EEDIDDIADLNSVNIADLSDEDEVDTMSPTIHTEATDYRRQAASASQPGELRGRKIMKRIVDIRELNEQAKVIDDLKKLGASEGTINQEI
QRYQQLESVAVNDIRRDVRKKLRRSSMRAASLKDKWGLSYKPSYSRSKSISASGRPPLKRMERASSRVGETEELPEIRVDAASPGPRVTF
NIQDTFPEETELDLLSVTIEGPSHYSSNSEGSCSVFSSPKTPGGFSPGIPFQTEEGRRDDSLSSTSEDSEKDEKDEDHERERFYIYRKPS
HTSRKKATGFAAVHQLFTERWPTTPVNRSLSGTATERNIDFELDIRVEIDSGKCVLHPTTLLQEHDDISLRRSYDRSSRSLDQDSPSKKK
KFQTNYASTTHLMTGKKVPSSLQTKPSDLETTVFYIPGVDVKLHYNSKTLKTESPNASRGSSLPRTLSKESKLYGMKDSATSPPSPPLPS
TVQSKTNTLLPPQPPPIPAAKGKGSGGVKTAKLYAWVALQSLPEEMVISPCLLDFLEKALETIPITPVERNYTAVSSQDEDMGHFEIPDP
MEESTTSLVSSSTSAYSSFPVDVVVYVRVQPSQIKFSCLPVSRVECMLKLPSLDLVFSSNRGELETLGTTYPAETLSPGGNATQSGTKTS
ASKTGIPGSSGLGSPLGRSRHSSSQSDLTSSSSSSSGLSFTACMSDFSLYVFHPYGAGKQKTAVSGLTPGSGGLGNVDEEPTSVTGRKDS
LSINLEFVKVSLSRIRRSGGASFFESQSVSKSASKMDTTLINISAVCDIGSASFKYDMRRLSEILAFPRAWYRRSIARRLFLGDQTINLP
TSGPGTPDSIEGVSQHLSPESSRKAYCKTWEQPSQSASFTHMPQSPNVFNEHMTNSTMSPGTVGQSLKSPASIRSRSVSDSSVPRRDSLS
KTSTPFNKSNKAASQQGTPWETLVVFAINLKQLNVQMNMSNVMGNTTWTTSGLKSQGRLSVGSNRDREISMSVGLGRSQLDSKGGVVGGT
IDVNALEMVAHISEHPNQQPSHKIQITMGSTEARVDYMGSSILMGIFSNADLKLQDEWKVNLYNTLDSSITDKSEIFVHGDLKWDIFQVM
ISRSTTPDLIKIGMKLQEFFTQQFDTSKRALSTWGPVPYLPPKTMTSNLEKSSQEQLLDAAHHRHWPGVLKVVSGCHISLFQIPLPEDGM
QFGGSMSLHGNHMTLACFHGPNFRSKSWALFHLEEPNIAFWTEAQKIWEDGSSDHSTYIVQTLDFHLGHNTMVTKPCGALESPMATITKI
TRRRHENPPHGVASVKEWFNYVTATRNEELNLLRNVDANNTENSTTVKNSSLLSGFRGGSSYNHETETIFALPRMQLDFKSIHVQEPQEP
SLQDASLKPKVECSVVTEFTDHICVTMDAELIMFLHDLVSAYLKEKEKAIFPPRILSTRPGQKSPIIIHDDNSSDKDREDSITYTTVDWR
DFMCNTWHLEPTLRLISWTGRKIDPVGVDYILQKLGFHHARTTIPKWLQRGVMDPLDKVLSVLIKKLGTALQDEKEKKGKDKEEH

--------------------------------------------------------------
>10454_10454_3_BTBD2-KIAA1109_BTBD2_chr19_1990002_ENST00000255608_KIAA1109_chr4_123107190_ENST00000455637_length(transcript)=11690nt_BP=1005nt
CACGCCGCAGCCACAAAATGGCGGCGGGTGGGAGCGGCGGGCGTGCGTCGTGCCCGCCGGGGGTCGGGGTCGGCCCGGGCACGGGGGGCA
GTCCCGGGCCCAGCGCCAACGCCGCCGCCACCCCGGCCCCCGGCAACGCGGCCGCCGCCGCCGCCGCCGCCGCCGCCGCCGCCGCCGCCC
CTGGGCCGACGCCGCCCGCCCCGCCGGGCCCCGGGACAGACGCGCAGGCCGCGGGCGCGGAGCGGGCGGAGGAGGCGGCGGGCCCGGGGG
CGGCGGCGCTGCAGCGCGAGGCCGCGTACAACTGGCAGGCCAGCAAGCCCACCGTGCAGGAGCGCTTCGCCTTCCTCTTCAACAACGAGG
TGCTGTGCGACGTGCACTTCCTGGTGGGCAAGGGGCTCAGCTCGCAGCGCATCCCCGCGCACAGGTTCGTGCTGGCCGTGGGCAGCGCCG
TCTTTGATGCCATGTTCAACGGGGGAATGGCCACAACATCCACGGAGATTGAGCTGCCCGACGTGGAACCCGCTGCCTTCCTCGCACTGC
TCAAGTTTCTCTACTCGGACGAGGTGCAGATTGGCCCGGAGACGGTGATGACCACGCTATACACCGCCAAGAAGTACGCGGTGCCAGCGC
TCGAGGCCCATTGCGTGGAGTTCCTGAAGAAGAACCTGCGAGCCGACAACGCCTTCATGCTGCTCACGCAGGCGCGACTCTTCGATGAAC
CGCAGCTGGCCAGCCTGTGCCTGGAGAACATCGACAAAAACACTGCAGACGCCATCACCGCGGAGGGCTTCACCGACATTGACCTGGACA
CGCTGGTGGCTGTCCTGGAGCGCGACACACTGGGCATCCGTGAGGTGCGGCTGTTCAATGCCGTTGTCCGCTGGTCCGAGGCCGAGTGTC
AGCGGCAGCAGCTGCAGGTGACGCCAGAGAACAGGCGGAAGGTTCTGGGCAAGGCCCTGGGCCTCATTCGCTTCCCGCTCATGACCATCG
AGGAGTTCGCTGCAGATCCAAAGGCAGAAACCAGGTTATACATCACAGTCAATGACTTTGAATTTCATGTCTATAATCGCTCGGATCTTT
ATGGACGCCTTCAAGAGTTGTTTGGTTTGGAGCCAACAATAATTCCACCTAAGAAAGATGATGATAAAACACGGGAAATTGGAAGAACAA
GAACCCAATCGAAAATTGAAAGAGTTAAAGTAAAAACAGAATCCCAAGACCCCACATCTTCATGGAGATCACTTATTCCAGTCATAAAGG
TCAATGTGAGCACAGGACGTTTGGCCTTTGGAAATCACTACCAGCCGCAAACTCTGTGCATCAACTTTGATGATGCTTTCTTAACTTATA
CTACAAAACCACCTTCAAGTCATCTTGACCAATTCATGCATATTGTGAAAGGAAAGCTTGAAAATGTTCGAGTCATGCTTGTTCCTAGTC
CAAGATATGTTGGTCTTCAAAATGATGAACCACCGAGATTAATGGGAGAAGGTTTTGTGGTGATGCAGTCAAATGATGTTGACATCTACT
ACTACATGGATGAGCCAGGACTTGTTCCGGAAGAAACAGAAGAAAATATTGAAGGAGAAATGAGCAGTGAGGATTGCAAATTACAAGACT
TGCCTCCATGTTGGGGACTGGATATAGTTTGTGGTAAAGGAACAGATTTTAATTATGGACCATGGGCCGATAGGCAGAGAGATTGTTTGT
GGAAGTTTTTCTTTCCACCTGACTATCAAGTTCTGAAAGTTTCTGAAATTGCACAGCCTGGGAGACCAAGACAGATCCTTGCTTTTGAAT
TACGAATGAATATTATTGCAGATGCTACAATTGATTTGCTGTTTACCAAAAATAGGGAAACAAATGCTGTACATGTAAATGTAGGAGCTG
GCTCATATTTAGAAATTAATATTCCAATGACAGTTGAAGAAAATGGTTACACTCCTGCTATTAAGGGACAACTCTTACATGTGGATGCCA
CTACCAGCATGCAATATCGGACCCTTTTAGAAGCAGAAATGTTAGCATTCCACATCAATGCCAGCTACCCCCGAATATGGAACATGCCGC
AGACATGGCAGTGTGAATTAGAGGTTTATAAAGCCACTTACCACTTCATCTTTGCACAGAAAAACTTCTTTACAGATTTAATTCAAGACT
GGTCTAGTGACAGTCCTCCAGACATTTTTTCATTTGTTCCATATACGTGGAATTTTAAAATCATGTTTCATCAGTTTGAAATGATTTGGG
CTGCTAATCAACACAATTGGATCGACTGTTCTACTAAACAACAGGAAAATGTGTATCTGGCAGCCTGTGGAGAAACACTAAACATTGATT
TTTCTTTGCCTTTTACGGACTTTGTTCCAGCTACATGTAATACCAAGTTCTCTTTAAGAGGAGAAGATGTTGATCTTCATTTGTTTCTAC
CAGACTGCCACCCTAGTAAATATTCTTTATTTATGCTGGTAAAAAATTGCCATCCAAATAAGATGATTCATGATACTGGTATTCCTGCTG
AGTGTCAAAGTGGCCAGAAAACAGTTAAACCAAAATGGCGCAACGTTACTCAGGAAAAGTCTGGTTGGGTTGAATGCTGGACTGTCCCAA
GTGTCATGCTTACAATTGATTATACATGGCATCCAATTTATCCACAAAAAGCAGATGAACAGCTGAAACAATCATTATCAGAAATGGAAG
AGACAATGCTATCTGTATTAAGGCCATCCCAGAAGACATCAGACAGAGTTGTTTCTTCTCCCTCTACTTCTTCACGCCCACCTATTGATC
CCTCAGAACTTCCACCTGATAAACTTCATGTAGAAATGGAACTTTCTCCAGATTCTCAGATAACTCTCTATGGACCTCTACTAAATGCCT
TTTTGTGTATAAAGGAAAACTACTTTGGGGAAGATGACATGTATATGGATTTTGAAGAGGTTATCTCAAGTCCTGTTTTGTCACTGTCAA
CATCATCCAGCTCTGGGTGGACTGCTGTTGGAATGGAAAATGACAAAAAGGAAAATGAAGGTTCAGCCAAGTCAATTCATCCACTTGCCT
TGCGTCCTTGGGATATTACTGTACTTGTTAATTTGTACAAAGTTCATGGGCGTCTTCCTGTTCATGGAACTACTGATGGTCCTGAATGCC
CTACAGCTTTCTTGGAAAGACTATGTTTTGAAATGAAAAAAGGATTTAGGGAGACCATGCTGCAACTTATCCTGTCACCCCTGAATGTGT
TTGTCAGTGATAACTATCAGCAGCGACCCCCTGTGGATGAAGTACTCAGGGAAGGTCACATCAATTTGTCAGGTCTCCAGCTGAGAGCAC
ACGCTATGTTCTCAGCAGAAGGTCTTCCTTTGGGAAGCGATTCCTTAGAATACGCATGGTTAATTGATGTGCAGGCTGGAAGTCTTACAG
CTAAGGTCACAGCACCACAGCTGGCATGCCTCTTGGAGTGGGGACAGACATTTGTTTTTCATGTGGTATGTCGGGAGTATGAACTGGAAA
GACCGAAATCAGTTATAATATGTCAGCATGGAATTGATCGTCGGTTCTGTGAATCCAAGTTGAGTTGTATTCCTGGGCCTTGTCCAACTT
CAGATGATTTGAAATATACTATGATTCGTTTAGCAGTAGATGGAGCCGATATTTACATTGTTGAGCATGGTTGTGCTACAAATATAAAGA
TGGGTGCAATTCGAGTTGCAAACTGTAATCTCCACAATCAATCGGTTGGGGAAGGAATCAGTGCTGCAATTCAGGATTTTCAAGTGAGAC
AGTACATTGAGCAATTAAATAATTGCAGAATTGGACTTCAGCCTGCAGTGCTACGGAGGGCCTATTGGCTTGAAGCTGGGTCAGCCAATT
TAGGACTTATTACTGTTGATATTGCTTTAGCTGCTGACCATCATTCTAAACATGAGGCACAAAGACATTTCTTAGAAACTCATGATGCCA
GAACTAAGAGGTTGTGGTTTTTATGGCCAGATGATATCCTGAAGAATAAGAGGTGTAGAAACAAATGTGGTTGTCTCGGTGGCTGCAGAT
TCTTTGGTGGCACAGTAACTGGCCTAGATTTCTTCAAACTTGAAGAGTTGACACCTTCCAGTAGCTCTGCATTTTCAAGCACAAGTGCAG
AGTCTGATATGTATTATGGACAGTCTCTGCTACAGCCTGGAGAATGGATAATTACTAAAGAAATTCCCAAAATTATAGATGGTAATGTGA
ATGGCATGAAGAGGAAAGAATGGGAAAACAAATCAGTGGGAATAGAAGTAGAGAGAAAAACTCAGCACCTTAGTCTTCAAGTACCATTAC
GATCTCATAGTTCATCCTCTTCCTCAGAAGAGAACAGTAGTTCTAGTGCTGCACAGCCTTTGTTGGCTGGTGAAAAGGAAAGTCCTTCAT
CTGTTGCTGATGACCATTTGGTTCAAAAAGAGTTCTTGCATGGGACAAAAAGAGATGATGGCCAAGCAAGTATCCCTACAGAAATTTCAG
GAAACAGCCCTGTGTCTCCTAATACTCAGGATAAGTCAGTAGGTCAATCTCCTCTTAGATCTCCCTTGAAACGACAAGCCTCTGTCTGTT
CCACCCGTCTTGGAAGTACTAAGAGTCTTACTGCTGCTTTCTATGGGGACAAGCAGCCTGTAACAGTTGGAGTCCAGTTTAGTAGTGATG
TCTCTCGAAGTGATGAGAATGTACTAGACTCACCAAAGCAGAGGAGAAGTTTTGGTTCATTCCCATATACACCATCAGCAGACTCTAATT
CATTTCATCAGTATCGATCAATGGATTCCAGCATGTCAATGGCTGATAGTGAAGCCTACTTTTCTGCTGCTGAGGAATTTGAGCCCATTA
GCAGTGATGAAGGCCCTGGAACTTATCCGGGTAGAAAAAAGAAGAAAAAGCAAACCCAGCAGATTGACTACAGTAGGGGTTCCATATATC
ACAGTGTAGAAGGGCCACTTACTGGACATGGAGAAAGCATTCAGGATTCCAGAACTCTGCCATTCAAAACTCATCCTTCTCAGGCTTCAT
TTGTTTCTGCGTTAGGTGGAGAAGATGATGTTATAGAACATCTATATATTGTAGAAGGTGAGAAAACAGTGGAGAGTGAACAGATTACTC
CGCAACAACCCGTGATGAATTGTTATCAGACTTACCTTACTCAGTTCCAGGTAATTAATTGGTCAGTTAAGCACCCAACCAACAAAAGAA
CCTCTAAATCCTCATTGCATCGTCCCCTTGATCTGGATACACCAACCAGTGAAGAAAGTTCATCGTCATTTGAACAGCTTTCTGTTCCAA
CTTTTAAGGTTATCAAGCAGGGGCTCACAGCTAATTCTTTGCTAGACAGAGGCATGCAACTTTCAGGATCAACTTCAAATACGCCGTATA
CTCCATTGGAAAAAAAACTCGCTGATAACACAGATGATGAAACATTAACAGAAGAGTGGACCCTGGATCAACCAGTGTCCCAGACCAGGA
CAACAGCCATAGTTGAAGTAAAAGGAACTGTTGATATTGTTTTGACTCCCCTGGTGGCTGAAGCTTTAGACAGATATATTGAAGCAATGG
TTCATTGTGCTAGTACCCGACATCCAGCTGCAATTGTAGATGATCTTCATGCTAAAGTCCTCAGGGAAGCTGTCCAAAATAGCAAGACTA
CCTTTTCAGAAAATTTATCTTCCAAACAAGACATTAGAGGAACAAAAACTGAGCAGTCTACAATAGGAACGACTAACCAAGGACAAGCAC
AGACAAATCTTACAATGAAGCAAGATAATGTAACAATTAAAGGTCTTCAGACTAATGTTAGCATACCAAAGGTAAACTTATGTTTGTTAC
AAGCCTCAGTGGAAGAATCTCCAACTACGGCTCCTAGTAGGAGTGTGACTCATGTTTCCCTAGTGGCATTGTGTTTTGACAGAATTGCTA
CACAGGTTCGCATGAACAGAGGTGTGGTTGAAGAGACTTCAAACAATGCAGAACCTGGTAGAACATCAAATTTTGATAGGTATGTTCATG
CCACAAAGATGCAGCCTCAGTCATCTGGATCTCTCAGATCAAATGCTGGAGCAGAAAAAGGCAAAGAAATTGCAGCTAAGTTAAACATTC
ATCGAGTTCATGGGCAACTTAGGGGTCTTGATACAACAGACATTGGGACCTGTGCAATCACTGCTATTCCTTTTGAGAAGTCCAAAGTTT
TATTTACTCTTGAAGAGTTGGATGAATTTACTTTTGTGGATGAAACTGATCAGCAAGCTGTTCCAGATGTAACTCGAATAGGTCCCAGCC
AAGAAAAATGGGGATGGATAATGTTTGAATGTGGACTTGAAAATTTAACCATAAAAGGAGGAAGACAGTCTGGTGCTGTTTTATATAACA
GTTTTGGAATTATGGGTAAAGCTAGTGACACAGAAAGGGGTGGAGTGCTGACATCCAATAATTCTTCTGATTCTCCAACCGGCAGTGGCT
ATAATACTGATGTCTCTGATGATAATCTTCCATGTGACCGGACAAGCCCTTCCTCAGACTTAAATGGAAATTCTGTTTCAGATGAACAGG
ATGAAGGAGTCGAATCTGATGATTTGAAAAAAGATCTACCTCTGATGCCTCCTCCTCCAGATTCATGTAGCATGAAGTTGACCATTAAAG
AAATTTGGTTTAGTTTTGCAGCTCCCACCAATGTGAGATCTCACACACATGCATTTTCTAGGCAGCTGAACCTTTTAAGCACTGCAACAC
CAGCTGTTGGTGCATGGCTTGTTCCCATTGACCAACTCAAGTCATCTTTAAACAAATTGGAAACTGAGGGAACCTTGAGAATTTGTGCTG
TTATGGGATGCATAATGACAGAAGCATTAGAGAATAAAAGTGTACATTTTCCCCTAAGAAGTAAATACAACAGGCTTACAAAAGTTGCTC
GCTTTCTCCAAGAAAATCCTTCATGTTTACTATGTAATATACTACACCACTATCTGCACCAGGCAAATTACTCCATCATTGATGATGCTA
CAATGAGCGATGGACTTCCTGCTTTGGTAACTTTGAAGAAAGGTTTAGTTGCACTGGCAAGGCAGTGGATGAAGTTTATTGTGGTGACAC
CAGCCTTTAAAGGAGTTAGCTTACATAGACCAGCTCAGCCTCTGAAACCTCAAATAGCTATGGACCATGAACATGAAGATGGACTTGGAT
TGGACAATGGGGGTGGTCTTCAAAGTGATACCAGTGCTGATGGAGCAGAATTTGAGTTCGATGCAGCCACAGTCAGTGAACACACAATGC
TATTAGAAGGAACAGCTAACCGGCCTCCACCTGGTAGCTCTGGACCTGTAACTGGAGCTGAGATAATGAGGAAACTTTCTAAAACTCATA
CCCATAGTGACTCTGCATTAAAAATAAAGGGCATTCACCCATATCATTCTCTGAGCTATACCAGTGGAGACACTGCCACTGATTCTCCAG
TGCATGTTGGACGTGCTGGGATGCCAGTAAAGGACAGTCCAAGGAAGGAGAGCCTACTCAGCTACCTGACTGGAAGCTTCCCAAGCCTGC
ACAACCTCCTGGAAGGTACTCCTCAGAGAAGCAGTGCTGCTGTGAAAAGTAGCTCCCTAACGAGAACAGGAAATACAGTAGCCACTGATA
TGTTATCTGAACATCCCTTGCTATCTGAGCCATCATCTGTGAGTTTCTATAATTGGATGTCAAATGCTGTGGGTAATCGAGGAAGTGTGT
TACAAGAATCTCCTGTTACAAAATCAGGACACAATAGTCTTCCCACAGGTGTTGCACCCAATCTTCCAACAATACCCTCAGCCTCAGATT
TCAACACTGTCTTGTCTAGTGACCAAAATACTTTGGATGGGACACATTCTCAGCATAGCACCAGTCAGGATGATGTGGCAGGTGTAGAAG
AAGCAAACCAAGGGTTTCCTGCTGTTCAGCTTGCTGATGCACAGGTTGTTTTCAAGCCTCTTCTGAGTCATACAGGGATCCAGTCACAGG
ATACAATGCCATTCTGCTACCGAATGTACTTTGGAGAACACCTTTCATTTTCAGGGACTTTGGACTGCCTCAGAGCAGATATTGTGGATT
CAGACACAGCCAAAGAGAGAAAAGGCAAAAGAGCAAGAAGGCAAGGCCATGTGAATCTTCCTCCACTTGAGTTCAAACCAGCATTAATGT
TGGGAACCTTTAGCATCAGTGCTGTTGTAATGGAAAAGTCCGTGTGCACCCCTCAGAACTCTACCAGTGCCCTTTCTTTTCATGATCTCA
GCAAGCGGTATTATAACACCTTTCACTGCAACTTTACTATTTCCTGTCAGTCAATAAGCCAGCATGTAGATATGGCTTTGGTTCGTCTTA
TTCATCAGTTTAGCACAATGATAGATGACATCAAAGCAACTCAGACTGATATTAAACTTAGCAGATATACAGCCGGATCTGCTTCCCCAA
CACCTACCTTCAAAACCAGAAAACATCGGGACTTTCGTTCATCTGACTTTAGCCGCAGTTCTAGAGGAAGTCTTAATGGTGGCAATAGAG
TAAATAATGCAAAGAACAAACGGACCAACAATGAGAATAACAAAAAGGAATCTCGAAACAAGAATTCATTAGGAAGATCTGAAAGAAGAA
CATCAAAAGTGTCTAGGAAAGGTTCAAAAGATGTGGTGGATCACATGACTATTCATATGGATGACTCTGATTCAATTACAGTGTCAGAAC
AAAGTGAGCCTTCAGCTGAGTGCTGGCAGAATATGTATAAATTGCTTAACTTCTATTCACTTATCTCCGATCCAACAGGAATATTGGAAA
AGTCTTCAGAAACATTTGGACCAGCAGGAGTTCGGAGCCCTACAGAGCCAACATGTAAAGTTGTGTTTGAGAATGAACAAGACAACAGCA
GTTTGACTAAGACTCAGAGGAAACGTAGCTTGGTAACTTCTGAACCTCAGCATGTTACTCTAATAGTGTTTGGGATTGGCATGGTGAACC
GCACACACCTAGAGGCAGATATTGGTGGACTAACAATGGAATCAGAACTGAAGAGGATCCATGGCAGTTTTACTCTTAAGGAAAAAATGA
AAGATGTTTTACATCAAAAGATGACTGAGACTTGTGCTACTGCTCATATTGGTGGGGTTAATATTGTGCTGCTTGAAGGGATTACACCAA
ATATACAACTGGAGGATTTTCCTACATCTCCTACAAGTACAGCCAAACAAGAGTTTCTAACTGTAGTGAAATGTAGTATTGCCAAGTCCC
AAGCCCTCTACAGTGCCCAAAGAGGGCTGAAGACAAACAATGCTGCTGTGTTCAAAGTAGGAGCTATCAGTATCAACATTCCTCAGCACC
CTGCCACCTTACATAGCATGATGGTTCGAAGTTCTCACCAACTATCTAAACAAATCTCAGACCTAATCAGACAGCCTTCTACAGCCCCAC
AGCCTGTAAAAGAAGATATTGCAACCCCACTACCTTCTGAAAAAACCCCAACAAGTGTTAATCAAACTCCTGTTGAAACAAATGAATTTC
CTCAGCTACCAGAAGGCTTAGAAAAGAAGCCTATTGTTCTTAAATTCAGTGCCATGTTAGATGGTATAGCCATTGGAGCAGCACTTTTAC
CATCTCTGAAAGCAGAATACAAGATGGGAAGAATGAGAAGTCATGGAATGACAGGTGCACAGACAAGATTTACATTTGAGCTGCCAAATC
ACAGATTGCGTTTTACTTCAAAAGTTTCTGCCACAGATATGTCAACCATTCCTCCTTCTGCCAGTCTTAACCTTCCCCCTGTTACCATGT
CAGGGAAATATATAATGGAAGAACATGATAGTTATTCGGATCAGGTGTGGAGTATAGATGAACTGCCTTCTAAACAAGGTTACTATTTAC
AGGGAAATTATCTGCGTTGTGTGGCAGAAGTTGGTTCCTTTGAACATAATCTTACAACTGATCTTCTAAACCACTTGGTATTTGTACAGA
AAGTGTTCATGAAGGAAGTTAATGAAGTAATACAAAAAGTTTCTGGTGGGGAGCAGCCTATTCCTCTCTGGAACGAACATGATGGAACAG
CAGATGGAGATAAACCTAAAATTCTCCTCTATTCCCTAAACTTGCAGTTCAAGGGTATTCAAGTAACGGCCACTACTCCATCAATGAGAG
CTGTAAGATTTGAAACTGGATTGATTGAACTGGAACTTTCTAACCGACTTCAAACCAAAGCTTCACCAGGAAGTAGCAGCTATCTGAAAC
TGTTTGGCAAATGCCAGGTGGATTTAAATCTGGCATTAGGACAAATTGTCAAACATCAGGTTTATGAGGAAGCTGGTTCTGATTTTCATC
AAGTTGCCTATTTTAAAACCAGAATTGGATTAAGAAATGCCCTCCGAGAAGAAATCAGTGGTTCTTCAGATAGGGAAGCTGTGCTTATTA
CTTTGAATAGACCAATTGTTTATGCACAGCCTGTGGCCTTTGATAGAGCTGTGCTGTTTTGGCTGAATTATAAGGCCGCCTATGACAACT
GGAATGAACAACGAATGGCTTTACATAAGGATATTCATATGGCTACAAAGGAAGTAGTAGATATGCTACCTGGTATCCAGCAAACATCAG
CCCAGGCCTTTGGGACTCTTTTTCTCCAGCTCACTGTCAATGATCTGGGAATTTGCCTACCTATCACAAATACTGCACAGTCTAATCATA
CTGGAGACCTTGACACTGGTTCTGCTTTGGTATTAACCATTGAAAGTACTCTCATCACTGCATGCTCTTCAGAGTCTCTGGTTAGCAAAG
GGCATTTCAAAAACTTTTGTATCCGTTTTGCTGATGGATTTGAGACATCATGGGATGACTGGAAACCAGAAATTCATGGGGATTTAGTGA
TGAATGCCTGTGTAGTTCCAGATGGCACCTATGAAGTATGTTCAAGAACTACAGGACAAGCAGCAGCTGAAAGCAGTAGTGCTGGAACCT
GGACACTCAACGTATTGTGGAAAATGTGTGGGATTGATGTTCACATGGATCCTAACATTGGCAAAAGGCTTAATGCTCTGGGCAATACTC
TTACAACACTGACAGGAGAGGAAGACATAGATGACATTGCTGACTTAAATTCAGTGAACATAGCTGACCTGTCAGATGAGGATGAAGTTG
ATACTATGTCTCCCACTATCCATACTGAAGCCACAGATTATCGAAGACAGGCAGCATCTGCTAGCCAGCCGGGAGAACTTAGAGGAAGAA
AAATTATGAAGCGTATAGTGGATATCAGAGAACTGAATGAACAGGCCAAAGTAATAGATGATCTGAAAAAATTAGGTGCAAGTGAAGGAA
CCATAAACCAGGAAATTCAACGTTACCAACAGTTAGAATCTGTGGCTGTGAATGACATTAGAAGAGATGTTCGTAAAAAATTACGGAGGT
CCAGTATGCGGGCTGCTTCCCTAAAGGATAAGTGGGGTTTGAGTTACAAACCAAGTTACAGCCGATCAAAAAGCATTTCTGCTTCTGGAA
GACCACCTCTTAAGCGAATGGAAAGGGCAAGTTCTCGAGTAGGAGAAACTGAAGAGCTCCCAGAAATCCGTGTGGATGCAGCATCTCCTG
GACCTAGAGTAACTTTTAATATCCAGGATACAATAGCAGAAATTAGAAGGAAGAAGATCAGCTTCAAAGTTGTATTCTAA

>10454_10454_3_BTBD2-KIAA1109_BTBD2_chr19_1990002_ENST00000255608_KIAA1109_chr4_123107190_ENST00000455637_length(amino acids)=3891AA_BP=329
MAAGGSGGRASCPPGVGVGPGTGGSPGPSANAAATPAPGNAAAAAAAAAAAAAAPGPTPPAPPGPGTDAQAAGAERAEEAAGPGAAALQR
EAAYNWQASKPTVQERFAFLFNNEVLCDVHFLVGKGLSSQRIPAHRFVLAVGSAVFDAMFNGGMATTSTEIELPDVEPAAFLALLKFLYS
DEVQIGPETVMTTLYTAKKYAVPALEAHCVEFLKKNLRADNAFMLLTQARLFDEPQLASLCLENIDKNTADAITAEGFTDIDLDTLVAVL
ERDTLGIREVRLFNAVVRWSEAECQRQQLQVTPENRRKVLGKALGLIRFPLMTIEEFAADPKAETRLYITVNDFEFHVYNRSDLYGRLQE
LFGLEPTIIPPKKDDDKTREIGRTRTQSKIERVKVKTESQDPTSSWRSLIPVIKVNVSTGRLAFGNHYQPQTLCINFDDAFLTYTTKPPS
SHLDQFMHIVKGKLENVRVMLVPSPRYVGLQNDEPPRLMGEGFVVMQSNDVDIYYYMDEPGLVPEETEENIEGEMSSEDCKLQDLPPCWG
LDIVCGKGTDFNYGPWADRQRDCLWKFFFPPDYQVLKVSEIAQPGRPRQILAFELRMNIIADATIDLLFTKNRETNAVHVNVGAGSYLEI
NIPMTVEENGYTPAIKGQLLHVDATTSMQYRTLLEAEMLAFHINASYPRIWNMPQTWQCELEVYKATYHFIFAQKNFFTDLIQDWSSDSP
PDIFSFVPYTWNFKIMFHQFEMIWAANQHNWIDCSTKQQENVYLAACGETLNIDFSLPFTDFVPATCNTKFSLRGEDVDLHLFLPDCHPS
KYSLFMLVKNCHPNKMIHDTGIPAECQSGQKTVKPKWRNVTQEKSGWVECWTVPSVMLTIDYTWHPIYPQKADEQLKQSLSEMEETMLSV
LRPSQKTSDRVVSSPSTSSRPPIDPSELPPDKLHVEMELSPDSQITLYGPLLNAFLCIKENYFGEDDMYMDFEEVISSPVLSLSTSSSSG
WTAVGMENDKKENEGSAKSIHPLALRPWDITVLVNLYKVHGRLPVHGTTDGPECPTAFLERLCFEMKKGFRETMLQLILSPLNVFVSDNY
QQRPPVDEVLREGHINLSGLQLRAHAMFSAEGLPLGSDSLEYAWLIDVQAGSLTAKVTAPQLACLLEWGQTFVFHVVCREYELERPKSVI
ICQHGIDRRFCESKLSCIPGPCPTSDDLKYTMIRLAVDGADIYIVEHGCATNIKMGAIRVANCNLHNQSVGEGISAAIQDFQVRQYIEQL
NNCRIGLQPAVLRRAYWLEAGSANLGLITVDIALAADHHSKHEAQRHFLETHDARTKRLWFLWPDDILKNKRCRNKCGCLGGCRFFGGTV
TGLDFFKLEELTPSSSSAFSSTSAESDMYYGQSLLQPGEWIITKEIPKIIDGNVNGMKRKEWENKSVGIEVERKTQHLSLQVPLRSHSSS
SSSEENSSSSAAQPLLAGEKESPSSVADDHLVQKEFLHGTKRDDGQASIPTEISGNSPVSPNTQDKSVGQSPLRSPLKRQASVCSTRLGS
TKSLTAAFYGDKQPVTVGVQFSSDVSRSDENVLDSPKQRRSFGSFPYTPSADSNSFHQYRSMDSSMSMADSEAYFSAAEEFEPISSDEGP
GTYPGRKKKKKQTQQIDYSRGSIYHSVEGPLTGHGESIQDSRTLPFKTHPSQASFVSALGGEDDVIEHLYIVEGEKTVESEQITPQQPVM
NCYQTYLTQFQVINWSVKHPTNKRTSKSSLHRPLDLDTPTSEESSSSFEQLSVPTFKVIKQGLTANSLLDRGMQLSGSTSNTPYTPLEKK
LADNTDDETLTEEWTLDQPVSQTRTTAIVEVKGTVDIVLTPLVAEALDRYIEAMVHCASTRHPAAIVDDLHAKVLREAVQNSKTTFSENL
SSKQDIRGTKTEQSTIGTTNQGQAQTNLTMKQDNVTIKGLQTNVSIPKVNLCLLQASVEESPTTAPSRSVTHVSLVALCFDRIATQVRMN
RGVVEETSNNAEPGRTSNFDRYVHATKMQPQSSGSLRSNAGAEKGKEIAAKLNIHRVHGQLRGLDTTDIGTCAITAIPFEKSKVLFTLEE
LDEFTFVDETDQQAVPDVTRIGPSQEKWGWIMFECGLENLTIKGGRQSGAVLYNSFGIMGKASDTERGGVLTSNNSSDSPTGSGYNTDVS
DDNLPCDRTSPSSDLNGNSVSDEQDEGVESDDLKKDLPLMPPPPDSCSMKLTIKEIWFSFAAPTNVRSHTHAFSRQLNLLSTATPAVGAW
LVPIDQLKSSLNKLETEGTLRICAVMGCIMTEALENKSVHFPLRSKYNRLTKVARFLQENPSCLLCNILHHYLHQANYSIIDDATMSDGL
PALVTLKKGLVALARQWMKFIVVTPAFKGVSLHRPAQPLKPQIAMDHEHEDGLGLDNGGGLQSDTSADGAEFEFDAATVSEHTMLLEGTA
NRPPPGSSGPVTGAEIMRKLSKTHTHSDSALKIKGIHPYHSLSYTSGDTATDSPVHVGRAGMPVKDSPRKESLLSYLTGSFPSLHNLLEG
TPQRSSAAVKSSSLTRTGNTVATDMLSEHPLLSEPSSVSFYNWMSNAVGNRGSVLQESPVTKSGHNSLPTGVAPNLPTIPSASDFNTVLS
SDQNTLDGTHSQHSTSQDDVAGVEEANQGFPAVQLADAQVVFKPLLSHTGIQSQDTMPFCYRMYFGEHLSFSGTLDCLRADIVDSDTAKE
RKGKRARRQGHVNLPPLEFKPALMLGTFSISAVVMEKSVCTPQNSTSALSFHDLSKRYYNTFHCNFTISCQSISQHVDMALVRLIHQFST
MIDDIKATQTDIKLSRYTAGSASPTPTFKTRKHRDFRSSDFSRSSRGSLNGGNRVNNAKNKRTNNENNKKESRNKNSLGRSERRTSKVSR
KGSKDVVDHMTIHMDDSDSITVSEQSEPSAECWQNMYKLLNFYSLISDPTGILEKSSETFGPAGVRSPTEPTCKVVFENEQDNSSLTKTQ
RKRSLVTSEPQHVTLIVFGIGMVNRTHLEADIGGLTMESELKRIHGSFTLKEKMKDVLHQKMTETCATAHIGGVNIVLLEGITPNIQLED
FPTSPTSTAKQEFLTVVKCSIAKSQALYSAQRGLKTNNAAVFKVGAISINIPQHPATLHSMMVRSSHQLSKQISDLIRQPSTAPQPVKED
IATPLPSEKTPTSVNQTPVETNEFPQLPEGLEKKPIVLKFSAMLDGIAIGAALLPSLKAEYKMGRMRSHGMTGAQTRFTFELPNHRLRFT
SKVSATDMSTIPPSASLNLPPVTMSGKYIMEEHDSYSDQVWSIDELPSKQGYYLQGNYLRCVAEVGSFEHNLTTDLLNHLVFVQKVFMKE
VNEVIQKVSGGEQPIPLWNEHDGTADGDKPKILLYSLNLQFKGIQVTATTPSMRAVRFETGLIELELSNRLQTKASPGSSSYLKLFGKCQ
VDLNLALGQIVKHQVYEEAGSDFHQVAYFKTRIGLRNALREEISGSSDREAVLITLNRPIVYAQPVAFDRAVLFWLNYKAAYDNWNEQRM
ALHKDIHMATKEVVDMLPGIQQTSAQAFGTLFLQLTVNDLGICLPITNTAQSNHTGDLDTGSALVLTIESTLITACSSESLVSKGHFKNF
CIRFADGFETSWDDWKPEIHGDLVMNACVVPDGTYEVCSRTTGQAAAESSSAGTWTLNVLWKMCGIDVHMDPNIGKRLNALGNTLTTLTG
EEDIDDIADLNSVNIADLSDEDEVDTMSPTIHTEATDYRRQAASASQPGELRGRKIMKRIVDIRELNEQAKVIDDLKKLGASEGTINQEI
QRYQQLESVAVNDIRRDVRKKLRRSSMRAASLKDKWGLSYKPSYSRSKSISASGRPPLKRMERASSRVGETEELPEIRVDAASPGPRVTF
NIQDTIAEIRRKKISFKVVFX

--------------------------------------------------------------
>10454_10454_4_BTBD2-KIAA1109_BTBD2_chr19_1990003_ENST00000255608_KIAA1109_chr4_123107191_ENST00000264501_length(transcript)=16170nt_BP=1005nt
CACGCCGCAGCCACAAAATGGCGGCGGGTGGGAGCGGCGGGCGTGCGTCGTGCCCGCCGGGGGTCGGGGTCGGCCCGGGCACGGGGGGCA
GTCCCGGGCCCAGCGCCAACGCCGCCGCCACCCCGGCCCCCGGCAACGCGGCCGCCGCCGCCGCCGCCGCCGCCGCCGCCGCCGCCGCCC
CTGGGCCGACGCCGCCCGCCCCGCCGGGCCCCGGGACAGACGCGCAGGCCGCGGGCGCGGAGCGGGCGGAGGAGGCGGCGGGCCCGGGGG
CGGCGGCGCTGCAGCGCGAGGCCGCGTACAACTGGCAGGCCAGCAAGCCCACCGTGCAGGAGCGCTTCGCCTTCCTCTTCAACAACGAGG
TGCTGTGCGACGTGCACTTCCTGGTGGGCAAGGGGCTCAGCTCGCAGCGCATCCCCGCGCACAGGTTCGTGCTGGCCGTGGGCAGCGCCG
TCTTTGATGCCATGTTCAACGGGGGAATGGCCACAACATCCACGGAGATTGAGCTGCCCGACGTGGAACCCGCTGCCTTCCTCGCACTGC
TCAAGTTTCTCTACTCGGACGAGGTGCAGATTGGCCCGGAGACGGTGATGACCACGCTATACACCGCCAAGAAGTACGCGGTGCCAGCGC
TCGAGGCCCATTGCGTGGAGTTCCTGAAGAAGAACCTGCGAGCCGACAACGCCTTCATGCTGCTCACGCAGGCGCGACTCTTCGATGAAC
CGCAGCTGGCCAGCCTGTGCCTGGAGAACATCGACAAAAACACTGCAGACGCCATCACCGCGGAGGGCTTCACCGACATTGACCTGGACA
CGCTGGTGGCTGTCCTGGAGCGCGACACACTGGGCATCCGTGAGGTGCGGCTGTTCAATGCCGTTGTCCGCTGGTCCGAGGCCGAGTGTC
AGCGGCAGCAGCTGCAGGTGACGCCAGAGAACAGGCGGAAGGTTCTGGGCAAGGCCCTGGGCCTCATTCGCTTCCCGCTCATGACCATCG
AGGAGTTCGCTGCAGATCCAAAGGCAGAAACCAGGTTATACATCACAGTCAATGACTTTGAATTTCATGTCTATAATCGCTCGGATCTTT
ATGGACGCCTTCAAGAGTTGTTTGGTTTGGAGCCAACAATAATTCCACCTAAGAAAGATGATGATAAAACACGGGAAATTGGAAGAACAA
GAACCCAATCGAAAATTGAAAGAGTTAAAGTAAAAACAGAATCCCAAGACCCCACATCTTCATGGAGATCACTTATTCCAGTCATAAAGG
TCAATGTGAGCACAGGACGTTTGGCCTTTGGAAATCACTACCAGCCGCAAACTCTGTGCATCAACTTTGATGATGCTTTCTTAACTTATA
CTACAAAACCACCTTCAAGTCATCTTGACCAATTCATGCATATTGTGAAAGGAAAGCTTGAAAATGTTCGAGTCATGCTTGTTCCTAGTC
CAAGATATGTTGGTCTTCAAAATGATGAACCACCGAGATTAATGGGAGAAGGTTTTGTGGTGATGCAGTCAAATGATGTTGACATCTACT
ACTACATGGATGAGCCAGGACTTGTTCCGGAAGAAACAGAAGAAAATATTGAAGGAGAAATGAGCAGTGAGGATTGCAAATTACAAGACT
TGCCTCCATGTTGGGGACTGGATATAGTTTGTGGTAAAGGAACAGATTTTAATTATGGACCATGGGCCGATAGGCAGAGAGATTGTTTGT
GGAAGTTTTTCTTTCCACCTGACTATCAAGTTCTGAAAGTTTCTGAAATTGCACAGCCTGGGAGACCAAGACAGATCCTTGCTTTTGAAT
TACGAATGAATATTATTGCAGATGCTACAATTGATTTGCTGTTTACCAAAAATAGGGAAACAAATGCTGTACATGTAAATGTAGGAGCTG
GCTCATATTTAGAAATTAATATTCCAATGACAGTTGAAGAAAATGGTTACACTCCTGCTATTAAGGGACAACTCTTACATGTGGATGCCA
CTACCAGCATGCAATATCGGACCCTTTTAGAAGCAGAAATGTTAGCATTCCACATCAATGCCAGCTACCCCCGAATATGGAACATGCCGC
AGACATGGCAGTGTGAATTAGAGGTTTATAAAGCCACTTACCACTTCATCTTTGCACAGAAAAACTTCTTTACAGATTTAATTCAAGACT
GGTCTAGTGACAGTCCTCCAGACATTTTTTCATTTGTTCCATATACGTGGAATTTTAAAATCATGTTTCATCAGTTTGAAATGATTTGGG
CTGCTAATCAACACAATTGGATCGACTGTTCTACTAAACAACAGGAAAATGTGTATCTGGCAGCCTGTGGAGAAACACTAAACATTGATT
TTTCTTTGCCTTTTACGGACTTTGTTCCAGCTACATGTAATACCAAGTTCTCTTTAAGAGGAGAAGATGTTGATCTTCATTTGTTTCTAC
CAGACTGCCACCCTAGTAAATATTCTTTATTTATGCTGGTAAAAAATTGCCATCCAAATAAGATGATTCATGATACTGGTATTCCTGCTG
AGTGTCAAAGTGGCCAGAAAACAGTTAAACCAAAATGGCGCAACGTTACTCAGGAAAAGTCTGGTTGGGTTGAATGCTGGACTGTCCCAA
GTGTCATGCTTACAATTGATTATACATGGCATCCAATTTATCCACAAAAAGCAGATGAACAGCTGAAACAATCATTATCAGAAATGGAAG
AGACAATGCTATCTGTATTAAGGCCATCCCAGAAGACATCAGACAGAGTTGTTTCTTCTCCCTCTACTTCTTCACGCCCACCTATTGATC
CCTCAGAACTTCCACCTGATAAACTTCATGTAGAAATGGAACTTTCTCCAGATTCTCAGATAACTCTCTATGGACCTCTACTAAATGCCT
TTTTGTGTATAAAGGAAAACTACTTTGGGGAAGATGACATGTATATGGATTTTGAAGAGGTTATCTCAAGTCCTGTTTTGTCACTGTCAA
CATCATCCAGCTCTGGGTGGACTGCTGTTGGAATGGAAAATGACAAAAAGGAAAATGAAGGTTCAGCCAAGTCAATTCATCCACTTGCCT
TGCGTCCTTGGGATATTACTGTACTTGTTAATTTGTACAAAGTTCATGGGCGTCTTCCTGTTCATGGAACTACTGATGGTCCTGAATGCC
CTACAGCTTTCTTGGAAAGACTATGTTTTGAAATGAAAAAAGGATTTAGGGAGACCATGCTGCAACTTATCCTGTCACCCCTGAATGTGT
TTGTCAGTGATAACTATCAGCAGCGACCCCCTGTGGATGAAGTACTCAGGGAAGGTCACATCAATTTGTCAGGTCTCCAGCTGAGAGCAC
ACGCTATGTTCTCAGCAGAAGGTCTTCCTTTGGGAAGCGATTCCTTAGAATACGCATGGTTAATTGATGTGCAGGCTGGAAGTCTTACAG
CTAAGGTCACAGCACCACAGCTGGCATGCCTCTTGGAGTGGGGACAGACATTTGTTTTTCATGTGGTATGTCGGGAGTATGAACTGGAAA
GACCGAAATCAGTTATAATATGTCAGCATGGAATTGATCGTCGGTTCTGTGAATCCAAGTTGAGTTGTATTCCTGGGCCTTGTCCAACTT
CAGATGATTTGAAATATACTATGATTCGTTTAGCAGTAGATGGAGCCGATATTTACATTGTTGAGCATGGTTGTGCTACAAATATAAAGA
TGGGTGCAATTCGAGTTGCAAACTGTAATCTCCACAATCAATCGGTTGGGGAAGGAATCAGTGCTGCAATTCAGGATTTTCAAGTGAGAC
AGTACATTGAGCAATTAAATAATTGCAGAATTGGACTTCAGCCTGCAGTGCTACGGAGGGCCTATTGGCTTGAAGCTGGGTCAGCCAATT
TAGGACTTATTACTGTTGATATTGCTTTAGCTGCTGACCATCATTCTAAACATGAGGCACAAAGACATTTCTTAGAAACTCATGATGCCA
GAACTAAGAGGTTGTGGTTTTTATGGCCAGATGATATCCTGAAGAATAAGAGGTGTAGAAACAAATGTGGTTGTCTCGGTGGCTGCAGAT
TCTTTGGTGGCACAGTAACTGGCCTAGATTTCTTCAAACTTGAAGAGTTGACACCTTCCAGTAGCTCTGCATTTTCAAGCACAAGTGCAG
AGTCTGATATGTATTATGGACAGTCTCTGCTACAGCCTGGAGAATGGATAATTACTAAAGAAATTCCCAAAATTATAGATGGTAATGTGA
ATGGCATGAAGAGGAAAGAATGGGAAAACAAATCAGTGGGAATAGAAGTAGAGAGAAAAACTCAGCACCTTAGTCTTCAAGTACCATTAC
GATCTCATAGTTCATCCTCTTCCTCAGAAGAGAACAGTAGTTCTAGTGCTGCACAGCCTTTGTTGGCTGGTGAAAAGGAAAGTCCTTCAT
CTGTTGCTGATGACCATTTGGTTCAAAAAGAGTTCTTGCATGGGACAAAAAGAGATGATGGCCAAGCAAGTATCCCTACAGAAATTTCAG
GAAACAGCCCTGTGTCTCCTAATACTCAGGATAAGTCAGTAGGTCAATCTCCTCTTAGATCTCCCTTGAAACGACAAGCCTCTGTCTGTT
CCACCCGTCTTGGAAGTACTAAGAGTCTTACTGCTGCTTTCTATGGGGACAAGCAGCCTGTAACAGTTGGAGTCCAGTTTAGTAGTGATG
TCTCTCGAAGTGATGAGAATGTACTAGACTCACCAAAGCAGAGGAGAAGTTTTGGTTCATTCCCATATACACCATCAGCAGACTCTAATT
CATTTCATCAGTATCGATCAATGGATTCCAGCATGTCAATGGCTGATAGTGAAGCCTACTTTTCTGCTGCTGAGGAATTTGAGCCCATTA
GCAGTGATGAAGGCCCTGGAACTTATCCGGGTAGAAAAAAGAAGAAAAAGCAAACCCAGCAGATTGACTACAGTAGGGGTTCCATATATC
ACAGTGTAGAAGGGCCACTTACTGGACATGGAGAAAGCATTCAGGATTCCAGAACTCTGCCATTCAAAACTCATCCTTCTCAGGCTTCAT
TTGTTTCTGCGTTAGGTGGAGAAGATGATGTTATAGAACATCTATATATTGTAGAAGGTGAGAAAACAGTGGAGAGTGAACAGATTACTC
CGCAACAACCCGTGATGAATTGTTATCAGACTTACCTTACTCAGTTCCAGGTAATTAATTGGTCAGTTAAGCACCCAACCAACAAAAGAA
CCTCTAAATCCTCATTGCATCGTCCCCTTGATCTGGATACACCAACCAGTGAAGAAAGTTCATCGTCATTTGAACAGCTTTCTGTTCCAA
CTTTTAAGGTTATCAAGCAGGGGCTCACAGCTAATTCTTTGCTAGACAGAGGCATGCAACTTTCAGGATCAACTTCAAATACGCCGTATA
CTCCATTGGAAAAAAAACTCGCTGATAACACAGATGATGAAACATTAACAGAAGAGTGGACCCTGGATCAACCAGTGTCCCAGACCAGGA
CAACAGCCATAGTTGAAGTAAAAGGAACTGTTGATATTGTTTTGACTCCCCTGGTGGCTGAAGCTTTAGACAGATATATTGAAGCAATGG
TTCATTGTGCTAGTACCCGACATCCAGCTGCAATTGTAGATGATCTTCATGCTAAAGTCCTCAGGGAAGCTGTCCAAAATAGCAAGACTA
CCTTTTCAGAAAATTTATCTTCCAAACAAGACATTAGAGGAACAAAAACTGAGCAGTCTACAATAGGAACGACTAACCAAGGACAAGCAC
AGACAAATCTTACAATGAAGCAAGATAATGTAACAATTAAAGGTCTTCAGACTAATGTTAGCATACCAAAGGTAAACTTATGTTTGTTAC
AAGCCTCAGTGGAAGAATCTCCAACTACGGCTCCTAGTAGGAGTGTGACTCATGTTTCCCTAGTGGCATTGTGTTTTGACAGAATTGCTA
CACAGGTTCGCATGAACAGAGGTGTGGTTGAAGAGACTTCAAACAATGCAGAACCTGGTAGAACATCAAATTTTGATAGGTATGTTCATG
CCACAAAGATGCAGCCTCAGTCATCTGGATCTCTCAGATCAAATGCTGGAGCAGAAAAAGGCAAAGAAATTGCAGCTAAGTTAAACATTC
ATCGAGTTCATGGGCAACTTAGGGGTCTTGATACAACAGACATTGGGACCTGTGCAATCACTGCTATTCCTTTTGAGAAGTCCAAAGTTT
TATTTACTCTTGAAGAGTTGGATGAATTTACTTTTGTGGATGAAACTGATCAGCAAGCTGTTCCAGATGTAACTCGAATAGGTCCCAGCC
AAGAAAAATGGGGATGGATAATGTTTGAATGTGGACTTGAAAATTTAACCATAAAAGGAGGAAGACAGTCTGGTGCTGTTTTATATAACA
GTTTTGGAATTATGGGTAAAGCTAGTGACACAGAAAGGGGTGGAGTGCTGACATCCAATAATTCTTCTGATTCTCCAACCGGCAGTGGCT
ATAATACTGATGTCTCTGATGATAATCTTCCATGTGACCGGACAAGCCCTTCCTCAGACTTAAATGGAAATTCTGTTTCAGATGAACAGG
ATGAAGGAGTCGAATCTGATGATTTGAAAAAAGATCTACCTCTGATGCCTCCTCCTCCAGATTCATGTAGCATGAAGTTGACCATTAAAG
AAATTTGGTTTAGTTTTGCAGCTCCCACCAATGTGAGATCTCACACACATGCATTTTCTAGGCAGCTGAACCTTTTAAGCACTGCAACAC
CAGCTGTTGGTGCATGGCTTGTTCCCATTGACCAACTCAAGTCATCTTTAAACAAATTGGAAACTGAGGGAACCTTGAGAATTTGTGCTG
TTATGGGATGCATAATGACAGAAGCATTAGAGAATAAAAGTGTACATTTTCCCCTAAGAAGTAAATACAACAGGCTTACAAAAGTTGCTC
GCTTTCTCCAAGAAAATCCTTCATGTTTACTATGTAATATACTACACCACTATCTGCACCAGGCAAATTACTCCATCATTGATGATGCTA
CAATGAGCGATGGACTTCCTGCTTTGGTAACTTTGAAGAAAGGTTTAGTTGCACTGGCAAGGCAGTGGATGAAGTTTATTGTGGTGACAC
CAGCCTTTAAAGGAGTTAGCTTACATAGACCAGCTCAGCCTCTGAAACCTCAAATAGCTATGGACCATGAACATGAAGATGGACTTGGAT
TGGACAATGGGGGTGGTCTTCAAAGTGATACCAGTGCTGATGGAGCAGAATTTGAGTTCGATGCAGCCACAGTCAGTGAACACACAATGC
TATTAGAAGGAACAGCTAACCGGCCTCCACCTGGTAGCTCTGGACCTGTAACTGGAGCTGAGATAATGAGGAAACTTTCTAAAACTCATA
CCCATAGTGACTCTGCATTAAAAATAAAGGGCATTCACCCATATCATTCTCTGAGCTATACCAGTGGAGACACTGCCACTGATTCTCCAG
TGCATGTTGGACGTGCTGGGATGCCAGTAAAGGACAGTCCAAGGAAGGAGAGCCTACTCAGCTACCTGACTGGAAGCTTCCCAAGCCTGC
ACAACCTCCTGGAAGGTACTCCTCAGAGAAGCAGTGCTGCTGTGAAAAGTAGCTCCCTAACGAGAACAGGAAATACAGTAGCCACTGATA
TGTTATCTGAACATCCCTTGCTATCTGAGCCATCATCTGTGAGTTTCTATAATTGGATGTCAAATGCTGTGGGTAATCGAGGAAGTGTGT
TACAAGAATCTCCTGTTACAAAATCAGGACACAATAGTCTTCCCACAGGTGTTGCACCCAATCTTCCAACAATACCCTCAGCCTCAGATT
TCAACACTGTCTTGTCTAGTGACCAAAATACTTTGGATGGGACACATTCTCAGCATAGCACCAGTCAGGATGATGTGGCAGGTGTAGAAG
AAGCAAACCAAGGGTTTCCTGCTGTTCAGCTTGCTGATGCACAGGTTGTTTTCAAGCCTCTTCTGAGTCATACAGGGATCCAGTCACAGG
ATACAATGCCATTCTGCTACCGAATGTACTTTGGAGAACACCTTTCATTTTCAGGGACTTTGGACTGCCTCAGAGCAGATATTGTGGATT
CAGACACAGCCAAAGAGAGAAAAGGCAAAAGAGCAAGAAGGCAAGGCCATGTGAATCTTCCTCCACTTGAGTTCAAACCAGCATTAATGT
TGGGAACCTTTAGCATCAGTGCTGTTGTAATGGAAAAGTCCGTGTGCACCCCTCAGAACTCTACCAGTGCCCTTTCTTTTCATGATCTCA
GCAAGCGGTATTATAACACCTTTCACTGCAACTTTACTATTTCCTGTCAGTCAATAAGCCAGCATGTAGATATGGCTTTGGTTCGTCTTA
TTCATCAGTTTAGCACAATGATAGATGACATCAAAGCAACTCAGACTGATATTAAACTTAGCAGATATACAGCCGGATCTGCTTCCCCAA
CACCTACCTTCAAAACCAGAAAACATCGGGACTTTCGTTCATCTGACTTTAGCCGCAGTTCTAGAGGAAGTCTTAATGGTGGCAATAGAG
TAAATAATGCAAAGAACAAACGGACCAACAATGAGAATAACAAAAAGGAATCTCGAAACAAGAATTCATTAGGAAGATCTGAAAGAAGAA
CATCAAAAGTGTCTAGGAAAGGTTCAAAAGATGTGGTGGATCACATGACTATTCATATGGATGACTCTGATTCAATTACAGTGTCAGAAC
AAAGTGAGCCTTCAGCTGAGTGCTGGCAGAATATGTATAAATTGCTTAACTTCTATTCACTTATCTCCGATCCAACAGGAATATTGGAAA
AGTCTTCAGAAACATTTGGACCAGCAGGAGTTCGGAGCCCTACAGAGCCAACATGTAAAGTTGTGTTTGAGAATGAACAAGACAACAGCA
GTTTGACTAAGACTCAGAGGAAACGTAGCTTGGTAACTTCTGAACCTCAGCATGTTACTCTAATAGTGTTTGGGATTGGCATGGTGAACC
GCACACACCTAGAGGCAGATATTGGTGGACTAACAATGGAATCAGAACTGAAGAGGATCCATGGCAGTTTTACTCTTAAGGAAAAAATGA
AAGATGTTTTACATCAAAAGATGACTGAGACTTGTGCTACTGCTCATATTGGTGGGGTTAATATTGTGCTGCTTGAAGGGATTACACCAA
ATATACAACTGGAGGATTTTCCTACATCTCCTACAAGTACAGCCAAACAAGAGTTTCTAACTGTAGTGAAATGTAGTATTGCCAAGTCCC
AAGCCCTCTACAGTGCCCAAAGAGGGCTGAAGACAAACAATGCTGCTGTGTTCAAAGTAGGAGCTATCAGTATCAACATTCCTCAGCACC
CTGCCACCTTACATAGCATGATGGTTCGAAGTTCTCACCAACTATCTAAACAAATCTCAGACCTAATCAGACAGCCTTCTACAGCCCCAC
AGCCTGTAAAAGAAGATATTGCAACCCCACTACCTTCTGAAAAAACCCCAACAAGTGTTAATCAAACTCCTGTTGAAACAAATGAATTTC
CTCAGCTACCAGAAGGCTTAGAAAAGAAGCCTATTGTTCTTAAATTCAGTGCCATGTTAGATGGTATAGCCATTGGAGCAGCACTTTTAC
CATCTCTGAAAGCAGAATACAAGATGGGAAGAATGAGAAGTCATGGAATGACAGGTGCACAGACAAGATTTACATTTGAGCTGCCAAATC
ACAGATTGCGTTTTACTTCAAAAGTTTCTGCCACAGATATGTCAACCATTCCTCCTTCTGCCAGTCTTAACCTTCCCCCTGTTACCATGT
CAGGGAAATATATAATGGAAGAACATGATAGTTATTCGGATCAGGTGTGGAGTATAGATGAACTGCCTTCTAAACAAGGTTACTATTTAC
AGGGAAATTATCTGCGTTGTGTGGCAGAAGTTGGTTCCTTTGAACATAATCTTACAACTGATCTTCTAAACCACTTGGTATTTGTACAGA
AAGTGTTCATGAAGGAAGTTAATGAAGTAATACAAAAAGTTTCTGGTGGGGAGCAGCCTATTCCTCTCTGGAACGAACATGATGGAACAG
CAGATGGAGATAAACCTAAAATTCTCCTCTATTCCCTAAACTTGCAGTTCAAGGGTATTCAAGTAACGGCCACTACTCCATCAATGAGAG
CTGTAAGATTTGAAACTGGATTGATTGAACTGGAACTTTCTAACCGACTTCAAACCAAAGCTTCACCAGGAAGTAGCAGCTATCTGAAAC
TGTTTGGCAAATGCCAGGTGGATTTAAATCTGGCATTAGGACAAATTGTCAAACATCAGGTTTATGAGGAAGCTGGTTCTGATTTTCATC
AAGTTGCCTATTTTAAAACCAGAATTGGATTAAGAAATGCCCTCCGAGAAGAAATCAGTGGTTCTTCAGATAGGGAAGCTGTGCTTATTA
CTTTGAATAGACCAATTGTTTATGCACAGCCTGTGGCCTTTGATAGAGCTGTGCTGTTTTGGCTGAATTATAAGGCCGCCTATGACAACT
GGAATGAACAACGAATGGCTTTACATAAGGATATTCATATGGCTACAAAGGAAGTAGTAGATATGCTACCTGGTATCCAGCAAACATCAG
CCCAGGCCTTTGGGACTCTTTTTCTCCAGCTCACTGTCAATGATCTGGGAATTTGCCTACCTATCACAAATACTGCACAGTCTAATCATA
CTGGAGACCTTGACACTGGTTCTGCTTTGGTATTAACCATTGAAAGTACTCTCATCACTGCATGCTCTTCAGAGTCTCTGGTTAGCAAAG
GGCATTTCAAAAACTTTTGTATCCGTTTTGCTGATGGATTTGAGACATCATGGGATGACTGGAAACCAGAAATTCATGGGGATTTAGTGA
TGAATGCCTGTGTAGTTCCAGATGGCACCTATGAAGTATGTTCAAGAACTACAGGACAAGCAGCAGCTGAAAGCAGTAGTGCTGGAACCT
GGACACTCAACGTATTGTGGAAAATGTGTGGGATTGATGTTCACATGGATCCTAACATTGGCAAAAGGCTTAATGCTCTGGGCAATACTC
TTACAACACTGACAGGAGAGGAAGACATAGATGACATTGCTGACTTAAATTCAGTGAACATAGCTGACCTGTCAGATGAGGATGAAGTTG
ATACTATGTCTCCCACTATCCATACTGAAGCCACAGATTATCGAAGACAGGCAGCATCTGCTAGCCAGCCGGGAGAACTTAGAGGAAGAA
AAATTATGAAGCGTATAGTGGATATCAGAGAACTGAATGAACAGGCCAAAGTAATAGATGATCTGAAAAAATTAGGTGCAAGTGAAGGAA
CCATAAACCAGGAAATTCAACGTTACCAACAGTTAGAATCTGTGGCTGTGAATGACATTAGAAGAGATGTTCGTAAAAAATTACGGAGGT
CCAGTATGCGGGCTGCTTCCCTAAAGGATAAGTGGGGTTTGAGTTACAAACCAAGTTACAGCCGATCAAAAAGCATTTCTGCTTCTGGAA
GACCACCTCTTAAGCGAATGGAAAGGGCAAGTTCTCGAGTAGGAGAAACTGAAGAGCTCCCAGAAATCCGTGTGGATGCAGCATCTCCTG
GACCTAGAGTAACTTTTAATATCCAGGATACATTTCCAGAGGAGACAGAACTGGACCTTTTGTCAGTAACCATTGAAGGTCCATCCCATT
ATTCATCAAATAGTGAAGGATCATGTTCTGTGTTCAGTTCTCCCAAAACTCCAGGAGGCTTTTCACCAGGCATTCCTTTCCAAACTGAAG
AGGGCCGACGGGATGACAGTTTGTCTTCTACCAGTGAAGATTCCGAGAAGGATGAAAAAGATGAAGACCATGAGAGGGAAAGGTTTTATA
TTTACAGGAAACCCTCACATACGTCTCGTAAAAAAGCAACAGGCTTTGCTGCTGTTCATCAGCTATTTACAGAACGCTGGCCAACAACAC
CAGTCAATAGAAGTCTTAGTGGCACAGCTACAGAGAGAAATATTGACTTTGAACTTGATATACGGGTTGAAATTGATAGTGGAAAATGTG
TACTCCACCCAACCACCCTTCTACAAGAACATGATGATATAAGTTTGAGAAGGAGTTATGATCGAAGTTCCAGGAGCTTAGATCAAGATT
CACCTTCAAAAAAGAAGAAGTTTCAAACTAATTATGCTTCTACCACCCATTTAATGACCGGCAAGAAAGTGCCATCATCTCTACAGACAA
AGCCTAGTGACTTAGAAACAACAGTATTTTACATTCCCGGAGTTGATGTAAAGTTGCATTACAATTCCAAGACGCTAAAGACTGAATCAC
CTAATGCCTCCAGGGGATCTTCCTTGCCAAGAACACTGTCCAAAGAGTCCAAGCTGTATGGTATGAAAGATAGTGCAACATCTCCTCCTT
CTCCTCCTTTACCTTCCACTGTCCAGAGCAAGACTAACACCTTACTTCCTCCCCAGCCCCCACCTATTCCTGCAGCCAAAGGAAAAGGAA
GTGGAGGAGTAAAAACAGCCAAGTTATATGCCTGGGTAGCACTTCAGTCATTGCCAGAAGAAATGGTTATTAGTCCCTGCCTATTAGACT
TTCTGGAAAAAGCTCTGGAAACTATCCCAATTACACCAGTTGAAAGGAATTATACAGCTGTCAGCTCACAAGATGAAGATATGGGACATT
TTGAAATACCAGATCCTATGGAAGAATCAACAACATCACTAGTGTCGTCTTCAACATCTGCTTACTCTTCCTTCCCTGTAGATGTTGTGG
TTTATGTACGAGTTCAGCCCTCACAGATCAAATTTAGCTGTTTACCAGTATCAAGAGTAGAATGCATGTTAAAGCTGCCATCCCTGGATT
TGGTGTTTTCTTCAAACCGAGGAGAACTGGAGACTTTAGGGACTACATATCCTGCAGAGACTTTATCCCCTGGAGGTAATGCTACTCAGA
GTGGAACAAAGACTTCTGCTAGCAAAACTGGAATACCAGGTTCATCGGGATTAGGCAGCCCTCTTGGCCGAAGTCGACATAGTAGTAGTC
AGTCAGACCTGACCAGTTCCAGCAGTAGTTCATCTGGCTTGAGCTTCACTGCATGCATGTCTGACTTTTCCCTTTATGTATTTCATCCAT
ATGGAGCAGGGAAACAAAAAACTGCTGTTTCTGGCCTCACACCTGGATCAGGAGGATTAGGGAATGTGGATGAGGAGCCCACTTCAGTCA
CTGGTCGAAAAGATTCACTCAGTATAAACCTTGAGTTTGTAAAAGTGAGTTTGTCACGGATCAGGCGTTCAGGAGGTGCCTCATTTTTTG
AAAGTCAGTCTGTAAGCAAGTCTGCAAGCAAAATGGATACTACGTTAATAAATATATCTGCTGTTTGTGATATAGGGTCTGCCTCCTTTA
AATATGATATGCGCCGACTCAGTGAAATTCTGGCATTTCCAAGAGCATGGTATAGAAGAAGTATTGCAAGACGTCTATTCCTTGGAGACC
AAACTATAAATTTGCCAACATCTGGCCCAGGGACACCTGATTCCATTGAAGGGGTAAGCCAACACCTTTCCCCTGAATCATCAAGAAAAG
CTTACTGCAAGACCTGGGAGCAGCCAAGTCAGTCAGCCTCCTTCACCCACATGCCTCAGTCACCTAATGTGTTCAATGAGCATATGACAA
ACAGCACCATGTCACCAGGGACAGTAGGACAGAGCCTAAAATCCCCAGCTTCCATAAGATCAAGGAGTGTATCTGATTCTTCAGTTCCTC
GAAGAGATTCACTTTCAAAAACATCAACTCCTTTTAACAAATCAAACAAAGCAGCAAGCCAACAAGGGACCCCATGGGAAACACTTGTCG
TGTTTGCTATCAACTTGAAGCAATTAAACGTTCAAATGAATATGAGTAATGTAATGGGAAATACAACTTGGACAACTAGTGGTTTGAAGA
GCCAGGGCCGTCTGTCAGTAGGAAGTAATCGTGATCGAGAGATCAGCATGTCTGTTGGTCTGGGAAGATCACAATTAGATTCTAAAGGAG
GAGTAGTTGGAGGGACCATAGATGTCAATGCTTTGGAGATGGTTGCTCATATTTCTGAACATCCAAATCAGCAACCCAGTCACAAAATTC
AGATTACTATGGGTTCTACTGAAGCTCGTGTTGATTACATGGGCTCAAGTATCCTCATGGGCATCTTCAGTAATGCTGATCTTAAGCTTC
AGGATGAATGGAAAGTAAACTTGTATAATACATTGGATTCAAGCATAACTGATAAAAGTGAGATTTTCGTCCATGGAGATTTGAAGTGGG
ATATTTTCCAAGTAATGATATCAAGGTCAACCACACCAGATCTGATAAAAATAGGAATGAAGCTCCAGGAATTTTTCACACAACAATTTG
ATACCAGCAAACGAGCTCTGTCTACCTGGGGACCAGTTCCTTACCTTCCGCCAAAGACAATGACTAGCAACCTAGAAAAAAGTTCACAAG
AACAATTACTTGATGCAGCACATCATCGACACTGGCCTGGAGTATTGAAGGTGGTATCAGGATGCCACATATCCTTATTTCAGATTCCAT
TACCAGAAGATGGAATGCAATTTGGAGGATCAATGAGCTTACATGGAAATCATATGACACTGGCATGTTTTCATGGTCCAAATTTTCGTT
CAAAATCTTGGGCCCTTTTTCATTTAGAAGAACCAAATATTGCTTTTTGGACTGAAGCTCAGAAAATCTGGGAAGATGGCTCCAGTGATC
ATTCTACATATATTGTACAAACACTAGATTTTCACCTGGGTCATAATACTATGGTTACCAAACCATGTGGTGCTTTGGAAAGTCCTATGG
CAACAATAACCAAGATAACAAGGCGTCGCCATGAAAATCCACCCCATGGAGTAGCAAGTGTGAAAGAATGGTTCAATTATGTTACAGCTA
CAAGGAATGAAGAGCTAAATCTGCTTCGTAATGTTGATGCTAACAACACTGAGAATAGCACTACTGTGAAGAATTCTAGTTTGTTGAGTG
GATTCAGAGGAGGTTCTAGCTACAACCATGAAACAGAGACTATCTTTGCATTACCAAGGATGCAGCTTGACTTTAAATCCATTCATGTTC
AAGAACCACAGGAGCCTTCATTACAGGATGCCAGCCTGAAGCCAAAAGTAGAATGTAGTGTGGTGACAGAGTTCACTGACCACATTTGTG
TGACTATGGATGCTGAGCTCATCATGTTTCTTCATGATTTAGTATCAGCTTATCTTAAAGAAAAAGAAAAAGCCATCTTTCCACCTCGGA
TTTTATCTACTCGACCAGGACAAAAAAGTCCAATTATTATACATGACGACAATTCCTCTGATAAAGATAGAGAAGATAGCATCACTTATA
CTACTGTGGACTGGAGAGATTTTATGTGCAATACATGGCATCTAGAACCTACTCTTAGATTAATTTCTTGGACTGGAAGAAAGATTGATC
CAGTAGGTGTTGATTATATTCTTCAAAAATTGGGCTTTCATCATGCTAGGACTACTATTCCTAAATGGCTTCAAAGAGGAGTCATGGATC
CACTGGACAAGGTTCTGTCAGTTCTTATCAAAAAGCTCGGTACTGCACTACAGGATGAAAAGGAAAAGAAAGGCAAAGACAAAGAAGAAC
ACTAAAAAAGTAATTTGATCTGTGAACAAATTATGATTGTGTCTGTTTTATTACACTGGAGTGTTTTTTTAGTATAATAATTTGAAATAT
AACTTTAAAATAATTCTAAATTTGTGGCTATAATTAAAAGTTTGTAAGTTAACCTGTTCTAGTTCCATCATTCTGTGTACAGTGAAGTAT
TGCATGATAATGTAAATTTTGTGAAAAACTAGATTAAAATATATAACTGCTTGTTATGGTTTATAATTATATAATGTGCAATACAATTCC
TGCATCTTTAAAATGTCTGCAGAATAACTGTGAATTTTTTTGTTATTGGATTGGCCGTAACTTTTAGAAAAAAATCTTGTTGATGATAAT
GTGATTTTGGGGAGGTCATTAATTGCTTTTTCTTTTTTAAATGTAGACTTATATAAATACCTGTTTGTATATAGCTTGAGTAATTGTGAT
ATGATTGTATACCACTAAAATATTGTTAACTATTATAATAAAGTCACAGTAATGGTTTAA

>10454_10454_4_BTBD2-KIAA1109_BTBD2_chr19_1990003_ENST00000255608_KIAA1109_chr4_123107191_ENST00000264501_length(amino acids)=5215AA_BP=329
MAAGGSGGRASCPPGVGVGPGTGGSPGPSANAAATPAPGNAAAAAAAAAAAAAAPGPTPPAPPGPGTDAQAAGAERAEEAAGPGAAALQR
EAAYNWQASKPTVQERFAFLFNNEVLCDVHFLVGKGLSSQRIPAHRFVLAVGSAVFDAMFNGGMATTSTEIELPDVEPAAFLALLKFLYS
DEVQIGPETVMTTLYTAKKYAVPALEAHCVEFLKKNLRADNAFMLLTQARLFDEPQLASLCLENIDKNTADAITAEGFTDIDLDTLVAVL
ERDTLGIREVRLFNAVVRWSEAECQRQQLQVTPENRRKVLGKALGLIRFPLMTIEEFAADPKAETRLYITVNDFEFHVYNRSDLYGRLQE
LFGLEPTIIPPKKDDDKTREIGRTRTQSKIERVKVKTESQDPTSSWRSLIPVIKVNVSTGRLAFGNHYQPQTLCINFDDAFLTYTTKPPS
SHLDQFMHIVKGKLENVRVMLVPSPRYVGLQNDEPPRLMGEGFVVMQSNDVDIYYYMDEPGLVPEETEENIEGEMSSEDCKLQDLPPCWG
LDIVCGKGTDFNYGPWADRQRDCLWKFFFPPDYQVLKVSEIAQPGRPRQILAFELRMNIIADATIDLLFTKNRETNAVHVNVGAGSYLEI
NIPMTVEENGYTPAIKGQLLHVDATTSMQYRTLLEAEMLAFHINASYPRIWNMPQTWQCELEVYKATYHFIFAQKNFFTDLIQDWSSDSP
PDIFSFVPYTWNFKIMFHQFEMIWAANQHNWIDCSTKQQENVYLAACGETLNIDFSLPFTDFVPATCNTKFSLRGEDVDLHLFLPDCHPS
KYSLFMLVKNCHPNKMIHDTGIPAECQSGQKTVKPKWRNVTQEKSGWVECWTVPSVMLTIDYTWHPIYPQKADEQLKQSLSEMEETMLSV
LRPSQKTSDRVVSSPSTSSRPPIDPSELPPDKLHVEMELSPDSQITLYGPLLNAFLCIKENYFGEDDMYMDFEEVISSPVLSLSTSSSSG
WTAVGMENDKKENEGSAKSIHPLALRPWDITVLVNLYKVHGRLPVHGTTDGPECPTAFLERLCFEMKKGFRETMLQLILSPLNVFVSDNY
QQRPPVDEVLREGHINLSGLQLRAHAMFSAEGLPLGSDSLEYAWLIDVQAGSLTAKVTAPQLACLLEWGQTFVFHVVCREYELERPKSVI
ICQHGIDRRFCESKLSCIPGPCPTSDDLKYTMIRLAVDGADIYIVEHGCATNIKMGAIRVANCNLHNQSVGEGISAAIQDFQVRQYIEQL
NNCRIGLQPAVLRRAYWLEAGSANLGLITVDIALAADHHSKHEAQRHFLETHDARTKRLWFLWPDDILKNKRCRNKCGCLGGCRFFGGTV
TGLDFFKLEELTPSSSSAFSSTSAESDMYYGQSLLQPGEWIITKEIPKIIDGNVNGMKRKEWENKSVGIEVERKTQHLSLQVPLRSHSSS
SSSEENSSSSAAQPLLAGEKESPSSVADDHLVQKEFLHGTKRDDGQASIPTEISGNSPVSPNTQDKSVGQSPLRSPLKRQASVCSTRLGS
TKSLTAAFYGDKQPVTVGVQFSSDVSRSDENVLDSPKQRRSFGSFPYTPSADSNSFHQYRSMDSSMSMADSEAYFSAAEEFEPISSDEGP
GTYPGRKKKKKQTQQIDYSRGSIYHSVEGPLTGHGESIQDSRTLPFKTHPSQASFVSALGGEDDVIEHLYIVEGEKTVESEQITPQQPVM
NCYQTYLTQFQVINWSVKHPTNKRTSKSSLHRPLDLDTPTSEESSSSFEQLSVPTFKVIKQGLTANSLLDRGMQLSGSTSNTPYTPLEKK
LADNTDDETLTEEWTLDQPVSQTRTTAIVEVKGTVDIVLTPLVAEALDRYIEAMVHCASTRHPAAIVDDLHAKVLREAVQNSKTTFSENL
SSKQDIRGTKTEQSTIGTTNQGQAQTNLTMKQDNVTIKGLQTNVSIPKVNLCLLQASVEESPTTAPSRSVTHVSLVALCFDRIATQVRMN
RGVVEETSNNAEPGRTSNFDRYVHATKMQPQSSGSLRSNAGAEKGKEIAAKLNIHRVHGQLRGLDTTDIGTCAITAIPFEKSKVLFTLEE
LDEFTFVDETDQQAVPDVTRIGPSQEKWGWIMFECGLENLTIKGGRQSGAVLYNSFGIMGKASDTERGGVLTSNNSSDSPTGSGYNTDVS
DDNLPCDRTSPSSDLNGNSVSDEQDEGVESDDLKKDLPLMPPPPDSCSMKLTIKEIWFSFAAPTNVRSHTHAFSRQLNLLSTATPAVGAW
LVPIDQLKSSLNKLETEGTLRICAVMGCIMTEALENKSVHFPLRSKYNRLTKVARFLQENPSCLLCNILHHYLHQANYSIIDDATMSDGL
PALVTLKKGLVALARQWMKFIVVTPAFKGVSLHRPAQPLKPQIAMDHEHEDGLGLDNGGGLQSDTSADGAEFEFDAATVSEHTMLLEGTA
NRPPPGSSGPVTGAEIMRKLSKTHTHSDSALKIKGIHPYHSLSYTSGDTATDSPVHVGRAGMPVKDSPRKESLLSYLTGSFPSLHNLLEG
TPQRSSAAVKSSSLTRTGNTVATDMLSEHPLLSEPSSVSFYNWMSNAVGNRGSVLQESPVTKSGHNSLPTGVAPNLPTIPSASDFNTVLS
SDQNTLDGTHSQHSTSQDDVAGVEEANQGFPAVQLADAQVVFKPLLSHTGIQSQDTMPFCYRMYFGEHLSFSGTLDCLRADIVDSDTAKE
RKGKRARRQGHVNLPPLEFKPALMLGTFSISAVVMEKSVCTPQNSTSALSFHDLSKRYYNTFHCNFTISCQSISQHVDMALVRLIHQFST
MIDDIKATQTDIKLSRYTAGSASPTPTFKTRKHRDFRSSDFSRSSRGSLNGGNRVNNAKNKRTNNENNKKESRNKNSLGRSERRTSKVSR
KGSKDVVDHMTIHMDDSDSITVSEQSEPSAECWQNMYKLLNFYSLISDPTGILEKSSETFGPAGVRSPTEPTCKVVFENEQDNSSLTKTQ
RKRSLVTSEPQHVTLIVFGIGMVNRTHLEADIGGLTMESELKRIHGSFTLKEKMKDVLHQKMTETCATAHIGGVNIVLLEGITPNIQLED
FPTSPTSTAKQEFLTVVKCSIAKSQALYSAQRGLKTNNAAVFKVGAISINIPQHPATLHSMMVRSSHQLSKQISDLIRQPSTAPQPVKED
IATPLPSEKTPTSVNQTPVETNEFPQLPEGLEKKPIVLKFSAMLDGIAIGAALLPSLKAEYKMGRMRSHGMTGAQTRFTFELPNHRLRFT
SKVSATDMSTIPPSASLNLPPVTMSGKYIMEEHDSYSDQVWSIDELPSKQGYYLQGNYLRCVAEVGSFEHNLTTDLLNHLVFVQKVFMKE
VNEVIQKVSGGEQPIPLWNEHDGTADGDKPKILLYSLNLQFKGIQVTATTPSMRAVRFETGLIELELSNRLQTKASPGSSSYLKLFGKCQ
VDLNLALGQIVKHQVYEEAGSDFHQVAYFKTRIGLRNALREEISGSSDREAVLITLNRPIVYAQPVAFDRAVLFWLNYKAAYDNWNEQRM
ALHKDIHMATKEVVDMLPGIQQTSAQAFGTLFLQLTVNDLGICLPITNTAQSNHTGDLDTGSALVLTIESTLITACSSESLVSKGHFKNF
CIRFADGFETSWDDWKPEIHGDLVMNACVVPDGTYEVCSRTTGQAAAESSSAGTWTLNVLWKMCGIDVHMDPNIGKRLNALGNTLTTLTG
EEDIDDIADLNSVNIADLSDEDEVDTMSPTIHTEATDYRRQAASASQPGELRGRKIMKRIVDIRELNEQAKVIDDLKKLGASEGTINQEI
QRYQQLESVAVNDIRRDVRKKLRRSSMRAASLKDKWGLSYKPSYSRSKSISASGRPPLKRMERASSRVGETEELPEIRVDAASPGPRVTF
NIQDTFPEETELDLLSVTIEGPSHYSSNSEGSCSVFSSPKTPGGFSPGIPFQTEEGRRDDSLSSTSEDSEKDEKDEDHERERFYIYRKPS
HTSRKKATGFAAVHQLFTERWPTTPVNRSLSGTATERNIDFELDIRVEIDSGKCVLHPTTLLQEHDDISLRRSYDRSSRSLDQDSPSKKK
KFQTNYASTTHLMTGKKVPSSLQTKPSDLETTVFYIPGVDVKLHYNSKTLKTESPNASRGSSLPRTLSKESKLYGMKDSATSPPSPPLPS
TVQSKTNTLLPPQPPPIPAAKGKGSGGVKTAKLYAWVALQSLPEEMVISPCLLDFLEKALETIPITPVERNYTAVSSQDEDMGHFEIPDP
MEESTTSLVSSSTSAYSSFPVDVVVYVRVQPSQIKFSCLPVSRVECMLKLPSLDLVFSSNRGELETLGTTYPAETLSPGGNATQSGTKTS
ASKTGIPGSSGLGSPLGRSRHSSSQSDLTSSSSSSSGLSFTACMSDFSLYVFHPYGAGKQKTAVSGLTPGSGGLGNVDEEPTSVTGRKDS
LSINLEFVKVSLSRIRRSGGASFFESQSVSKSASKMDTTLINISAVCDIGSASFKYDMRRLSEILAFPRAWYRRSIARRLFLGDQTINLP
TSGPGTPDSIEGVSQHLSPESSRKAYCKTWEQPSQSASFTHMPQSPNVFNEHMTNSTMSPGTVGQSLKSPASIRSRSVSDSSVPRRDSLS
KTSTPFNKSNKAASQQGTPWETLVVFAINLKQLNVQMNMSNVMGNTTWTTSGLKSQGRLSVGSNRDREISMSVGLGRSQLDSKGGVVGGT
IDVNALEMVAHISEHPNQQPSHKIQITMGSTEARVDYMGSSILMGIFSNADLKLQDEWKVNLYNTLDSSITDKSEIFVHGDLKWDIFQVM
ISRSTTPDLIKIGMKLQEFFTQQFDTSKRALSTWGPVPYLPPKTMTSNLEKSSQEQLLDAAHHRHWPGVLKVVSGCHISLFQIPLPEDGM
QFGGSMSLHGNHMTLACFHGPNFRSKSWALFHLEEPNIAFWTEAQKIWEDGSSDHSTYIVQTLDFHLGHNTMVTKPCGALESPMATITKI
TRRRHENPPHGVASVKEWFNYVTATRNEELNLLRNVDANNTENSTTVKNSSLLSGFRGGSSYNHETETIFALPRMQLDFKSIHVQEPQEP
SLQDASLKPKVECSVVTEFTDHICVTMDAELIMFLHDLVSAYLKEKEKAIFPPRILSTRPGQKSPIIIHDDNSSDKDREDSITYTTVDWR
DFMCNTWHLEPTLRLISWTGRKIDPVGVDYILQKLGFHHARTTIPKWLQRGVMDPLDKVLSVLIKKLGTALQDEKEKKGKDKEEH

--------------------------------------------------------------
>10454_10454_5_BTBD2-KIAA1109_BTBD2_chr19_1990003_ENST00000255608_KIAA1109_chr4_123107191_ENST00000388738_length(transcript)=16176nt_BP=1005nt
CACGCCGCAGCCACAAAATGGCGGCGGGTGGGAGCGGCGGGCGTGCGTCGTGCCCGCCGGGGGTCGGGGTCGGCCCGGGCACGGGGGGCA
GTCCCGGGCCCAGCGCCAACGCCGCCGCCACCCCGGCCCCCGGCAACGCGGCCGCCGCCGCCGCCGCCGCCGCCGCCGCCGCCGCCGCCC
CTGGGCCGACGCCGCCCGCCCCGCCGGGCCCCGGGACAGACGCGCAGGCCGCGGGCGCGGAGCGGGCGGAGGAGGCGGCGGGCCCGGGGG
CGGCGGCGCTGCAGCGCGAGGCCGCGTACAACTGGCAGGCCAGCAAGCCCACCGTGCAGGAGCGCTTCGCCTTCCTCTTCAACAACGAGG
TGCTGTGCGACGTGCACTTCCTGGTGGGCAAGGGGCTCAGCTCGCAGCGCATCCCCGCGCACAGGTTCGTGCTGGCCGTGGGCAGCGCCG
TCTTTGATGCCATGTTCAACGGGGGAATGGCCACAACATCCACGGAGATTGAGCTGCCCGACGTGGAACCCGCTGCCTTCCTCGCACTGC
TCAAGTTTCTCTACTCGGACGAGGTGCAGATTGGCCCGGAGACGGTGATGACCACGCTATACACCGCCAAGAAGTACGCGGTGCCAGCGC
TCGAGGCCCATTGCGTGGAGTTCCTGAAGAAGAACCTGCGAGCCGACAACGCCTTCATGCTGCTCACGCAGGCGCGACTCTTCGATGAAC
CGCAGCTGGCCAGCCTGTGCCTGGAGAACATCGACAAAAACACTGCAGACGCCATCACCGCGGAGGGCTTCACCGACATTGACCTGGACA
CGCTGGTGGCTGTCCTGGAGCGCGACACACTGGGCATCCGTGAGGTGCGGCTGTTCAATGCCGTTGTCCGCTGGTCCGAGGCCGAGTGTC
AGCGGCAGCAGCTGCAGGTGACGCCAGAGAACAGGCGGAAGGTTCTGGGCAAGGCCCTGGGCCTCATTCGCTTCCCGCTCATGACCATCG
AGGAGTTCGCTGCAGATCCAAAGGCAGAAACCAGGTTATACATCACAGTCAATGACTTTGAATTTCATGTCTATAATCGCTCGGATCTTT
ATGGACGCCTTCAAGAGTTGTTTGGTTTGGAGCCAACAATAATTCCACCTAAGAAAGATGATGATAAAACACGGGAAATTGGAAGAACAA
GAACCCAATCGAAAATTGAAAGAGTTAAAGTAAAAACAGAATCCCAAGACCCCACATCTTCATGGAGATCACTTATTCCAGTCATAAAGG
TCAATGTGAGCACAGGACGTTTGGCCTTTGGAAATCACTACCAGCCGCAAACTCTGTGCATCAACTTTGATGATGCTTTCTTAACTTATA
CTACAAAACCACCTTCAAGTCATCTTGACCAATTCATGCATATTGTGAAAGGAAAGCTTGAAAATGTTCGAGTCATGCTTGTTCCTAGTC
CAAGATATGTTGGTCTTCAAAATGATGAACCACCGAGATTAATGGGAGAAGGTTTTGTGGTGATGCAGTCAAATGATGTTGACATCTACT
ACTACATGGATGAGCCAGGACTTGTTCCGGAAGAAACAGAAGAAAATATTGAAGGAGAAATGAGCAGTGAGGATTGCAAATTACAAGACT
TGCCTCCATGTTGGGGACTGGATATAGTTTGTGGTAAAGGAACAGATTTTAATTATGGACCATGGGCCGATAGGCAGAGAGATTGTTTGT
GGAAGTTTTTCTTTCCACCTGACTATCAAGTTCTGAAAGTTTCTGAAATTGCACAGCCTGGGAGACCAAGACAGATCCTTGCTTTTGAAT
TACGAATGAATATTATTGCAGATGCTACAATTGATTTGCTGTTTACCAAAAATAGGGAAACAAATGCTGTACATGTAAATGTAGGAGCTG
GCTCATATTTAGAAATTAATATTCCAATGACAGTTGAAGAAAATGGTTACACTCCTGCTATTAAGGGACAACTCTTACATGTGGATGCCA
CTACCAGCATGCAATATCGGACCCTTTTAGAAGCAGAAATGTTAGCATTCCACATCAATGCCAGCTACCCCCGAATATGGAACATGCCGC
AGACATGGCAGTGTGAATTAGAGGTTTATAAAGCCACTTACCACTTCATCTTTGCACAGAAAAACTTCTTTACAGATTTAATTCAAGACT
GGTCTAGTGACAGTCCTCCAGACATTTTTTCATTTGTTCCATATACGTGGAATTTTAAAATCATGTTTCATCAGTTTGAAATGATTTGGG
CTGCTAATCAACACAATTGGATCGACTGTTCTACTAAACAACAGGAAAATGTGTATCTGGCAGCCTGTGGAGAAACACTAAACATTGATT
TTTCTTTGCCTTTTACGGACTTTGTTCCAGCTACATGTAATACCAAGTTCTCTTTAAGAGGAGAAGATGTTGATCTTCATTTGTTTCTAC
CAGACTGCCACCCTAGTAAATATTCTTTATTTATGCTGGTAAAAAATTGCCATCCAAATAAGATGATTCATGATACTGGTATTCCTGCTG
AGTGTCAAAGTGGCCAGAAAACAGTTAAACCAAAATGGCGCAACGTTACTCAGGAAAAGTCTGGTTGGGTTGAATGCTGGACTGTCCCAA
GTGTCATGCTTACAATTGATTATACATGGCATCCAATTTATCCACAAAAAGCAGATGAACAGCTGAAACAATCATTATCAGAAATGGAAG
AGACAATGCTATCTGTATTAAGGCCATCCCAGAAGACATCAGACAGAGTTGTTTCTTCTCCCTCTACTTCTTCACGCCCACCTATTGATC
CCTCAGAACTTCCACCTGATAAACTTCATGTAGAAATGGAACTTTCTCCAGATTCTCAGATAACTCTCTATGGACCTCTACTAAATGCCT
TTTTGTGTATAAAGGAAAACTACTTTGGGGAAGATGACATGTATATGGATTTTGAAGAGGTTATCTCAAGTCCTGTTTTGTCACTGTCAA
CATCATCCAGCTCTGGGTGGACTGCTGTTGGAATGGAAAATGACAAAAAGGAAAATGAAGGTTCAGCCAAGTCAATTCATCCACTTGCCT
TGCGTCCTTGGGATATTACTGTACTTGTTAATTTGTACAAAGTTCATGGGCGTCTTCCTGTTCATGGAACTACTGATGGTCCTGAATGCC
CTACAGCTTTCTTGGAAAGACTATGTTTTGAAATGAAAAAAGGATTTAGGGAGACCATGCTGCAACTTATCCTGTCACCCCTGAATGTGT
TTGTCAGTGATAACTATCAGCAGCGACCCCCTGTGGATGAAGTACTCAGGGAAGGTCACATCAATTTGTCAGGTCTCCAGCTGAGAGCAC
ACGCTATGTTCTCAGCAGAAGGTCTTCCTTTGGGAAGCGATTCCTTAGAATACGCATGGTTAATTGATGTGCAGGCTGGAAGTCTTACAG
CTAAGGTCACAGCACCACAGCTGGCATGCCTCTTGGAGTGGGGACAGACATTTGTTTTTCATGTGGTATGTCGGGAGTATGAACTGGAAA
GACCGAAATCAGTTATAATATGTCAGCATGGAATTGATCGTCGGTTCTGTGAATCCAAGTTGAGTTGTATTCCTGGGCCTTGTCCAACTT
CAGATGATTTGAAATATACTATGATTCGTTTAGCAGTAGATGGAGCCGATATTTACATTGTTGAGCATGGTTGTGCTACAAATATAAAGA
TGGGTGCAATTCGAGTTGCAAACTGTAATCTCCACAATCAATCGGTTGGGGAAGGAATCAGTGCTGCAATTCAGGATTTTCAAGTGAGAC
AGTACATTGAGCAATTAAATAATTGCAGAATTGGACTTCAGCCTGCAGTGCTACGGAGGGCCTATTGGCTTGAAGCTGGGTCAGCCAATT
TAGGACTTATTACTGTTGATATTGCTTTAGCTGCTGACCATCATTCTAAACATGAGGCACAAAGACATTTCTTAGAAACTCATGATGCCA
GAACTAAGAGGTTGTGGTTTTTATGGCCAGATGATATCCTGAAGAATAAGAGGTGTAGAAACAAATGTGGTTGTCTCGGTGGCTGCAGAT
TCTTTGGTGGCACAGTAACTGGCCTAGATTTCTTCAAACTTGAAGAGTTGACACCTTCCAGTAGCTCTGCATTTTCAAGCACAAGTGCAG
AGTCTGATATGTATTATGGACAGTCTCTGCTACAGCCTGGAGAATGGATAATTACTAAAGAAATTCCCAAAATTATAGATGGTAATGTGA
ATGGCATGAAGAGGAAAGAATGGGAAAACAAATCAGTGGGAATAGAAGTAGAGAGAAAAACTCAGCACCTTAGTCTTCAAGTACCATTAC
GATCTCATAGTTCATCCTCTTCCTCAGAAGAGAACAGTAGTTCTAGTGCTGCACAGCCTTTGTTGGCTGGTGAAAAGGAAAGTCCTTCAT
CTGTTGCTGATGACCATTTGGTTCAAAAAGAGTTCTTGCATGGGACAAAAAGAGATGATGGCCAAGCAAGTATCCCTACAGAAATTTCAG
GAAACAGCCCTGTGTCTCCTAATACTCAGGATAAGTCAGTAGGTCAATCTCCTCTTAGATCTCCCTTGAAACGACAAGCCTCTGTCTGTT
CCACCCGTCTTGGAAGTACTAAGAGTCTTACTGCTGCTTTCTATGGGGACAAGCAGCCTGTAACAGTTGGAGTCCAGTTTAGTAGTGATG
TCTCTCGAAGTGATGAGAATGTACTAGACTCACCAAAGCAGAGGAGAAGTTTTGGTTCATTCCCATATACACCATCAGCAGACTCTAATT
CATTTCATCAGTATCGATCAATGGATTCCAGCATGTCAATGGCTGATAGTGAAGCCTACTTTTCTGCTGCTGAGGAATTTGAGCCCATTA
GCAGTGATGAAGGCCCTGGAACTTATCCGGGTAGAAAAAAGAAGAAAAAGCAAACCCAGCAGATTGACTACAGTAGGGGTTCCATATATC
ACAGTGTAGAAGGGCCACTTACTGGACATGGAGAAAGCATTCAGGATTCCAGAACTCTGCCATTCAAAACTCATCCTTCTCAGGCTTCAT
TTGTTTCTGCGTTAGGTGGAGAAGATGATGTTATAGAACATCTATATATTGTAGAAGGTGAGAAAACAGTGGAGAGTGAACAGATTACTC
CGCAACAACCCGTGATGAATTGTTATCAGACTTACCTTACTCAGTTCCAGGTAATTAATTGGTCAGTTAAGCACCCAACCAACAAAAGAA
CCTCTAAATCCTCATTGCATCGTCCCCTTGATCTGGATACACCAACCAGTGAAGAAAGTTCATCGTCATTTGAACAGCTTTCTGTTCCAA
CTTTTAAGGTTATCAAGCAGGGGCTCACAGCTAATTCTTTGCTAGACAGAGGCATGCAACTTTCAGGATCAACTTCAAATACGCCGTATA
CTCCATTGGAAAAAAAACTCGCTGATAACACAGATGATGAAACATTAACAGAAGAGTGGACCCTGGATCAACCAGTGTCCCAGACCAGGA
CAACAGCCATAGTTGAAGTAAAAGGAACTGTTGATATTGTTTTGACTCCCCTGGTGGCTGAAGCTTTAGACAGATATATTGAAGCAATGG
TTCATTGTGCTAGTACCCGACATCCAGCTGCAATTGTAGATGATCTTCATGCTAAAGTCCTCAGGGAAGCTGTCCAAAATAGCAAGACTA
CCTTTTCAGAAAATTTATCTTCCAAACAAGACATTAGAGGAACAAAAACTGAGCAGTCTACAATAGGAACGACTAACCAAGGACAAGCAC
AGACAAATCTTACAATGAAGCAAGATAATGTAACAATTAAAGGTCTTCAGACTAATGTTAGCATACCAAAGGTAAACTTATGTTTGTTAC
AAGCCTCAGTGGAAGAATCTCCAACTACGGCTCCTAGTAGGAGTGTGACTCATGTTTCCCTAGTGGCATTGTGTTTTGACAGAATTGCTA
CACAGGTTCGCATGAACAGAGGTGTGGTTGAAGAGACTTCAAACAATGCAGAACCTGGTAGAACATCAAATTTTGATAGGTATGTTCATG
CCACAAAGATGCAGCCTCAGTCATCTGGATCTCTCAGATCAAATGCTGGAGCAGAAAAAGGCAAAGAAATTGCAGCTAAGTTAAACATTC
ATCGAGTTCATGGGCAACTTAGGGGTCTTGATACAACAGACATTGGGACCTGTGCAATCACTGCTATTCCTTTTGAGAAGTCCAAAGTTT
TATTTACTCTTGAAGAGTTGGATGAATTTACTTTTGTGGATGAAACTGATCAGCAAGCTGTTCCAGATGTAACTCGAATAGGTCCCAGCC
AAGAAAAATGGGGATGGATAATGTTTGAATGTGGACTTGAAAATTTAACCATAAAAGGAGGAAGACAGTCTGGTGCTGTTTTATATAACA
GTTTTGGAATTATGGGTAAAGCTAGTGACACAGAAAGGGGTGGAGTGCTGACATCCAATAATTCTTCTGATTCTCCAACCGGCAGTGGCT
ATAATACTGATGTCTCTGATGATAATCTTCCATGTGACCGGACAAGCCCTTCCTCAGACTTAAATGGAAATTCTGTTTCAGATGAACAGG
ATGAAGGAGTCGAATCTGATGATTTGAAAAAAGATCTACCTCTGATGCCTCCTCCTCCAGATTCATGTAGCATGAAGTTGACCATTAAAG
AAATTTGGTTTAGTTTTGCAGCTCCCACCAATGTGAGATCTCACACACATGCATTTTCTAGGCAGCTGAACCTTTTAAGCACTGCAACAC
CAGCTGTTGGTGCATGGCTTGTTCCCATTGACCAACTCAAGTCATCTTTAAACAAATTGGAAACTGAGGGAACCTTGAGAATTTGTGCTG
TTATGGGATGCATAATGACAGAAGCATTAGAGAATAAAAGTGTACATTTTCCCCTAAGAAGTAAATACAACAGGCTTACAAAAGTTGCTC
GCTTTCTCCAAGAAAATCCTTCATGTTTACTATGTAATATACTACACCACTATCTGCACCAGGCAAATTACTCCATCATTGATGATGCTA
CAATGAGCGATGGACTTCCTGCTTTGGTAACTTTGAAGAAAGGTTTAGTTGCACTGGCAAGGCAGTGGATGAAGTTTATTGTGGTGACAC
CAGCCTTTAAAGGAGTTAGCTTACATAGACCAGCTCAGCCTCTGAAACCTCAAATAGCTATGGACCATGAACATGAAGATGGACTTGGAT
TGGACAATGGGGGTGGTCTTCAAAGTGATACCAGTGCTGATGGAGCAGAATTTGAGTTCGATGCAGCCACAGTCAGTGAACACACAATGC
TATTAGAAGGAACAGCTAACCGGCCTCCACCTGGTAGCTCTGGACCTGTAACTGGAGCTGAGATAATGAGGAAACTTTCTAAAACTCATA
CCCATAGTGACTCTGCATTAAAAATAAAGGGCATTCACCCATATCATTCTCTGAGCTATACCAGTGGAGACACTGCCACTGATTCTCCAG
TGCATGTTGGACGTGCTGGGATGCCAGTAAAGGACAGTCCAAGGAAGGAGAGCCTACTCAGCTACCTGACTGGAAGCTTCCCAAGCCTGC
ACAACCTCCTGGAAGGTACTCCTCAGAGAAGCAGTGCTGCTGTGAAAAGTAGCTCCCTAACGAGAACAGGAAATACAGTAGCCACTGATA
TGTTATCTGAACATCCCTTGCTATCTGAGCCATCATCTGTGAGTTTCTATAATTGGATGTCAAATGCTGTGGGTAATCGAGGAAGTGTGT
TACAAGAATCTCCTGTTACAAAATCAGGACACAATAGTCTTCCCACAGGTGTTGCACCCAATCTTCCAACAATACCCTCAGCCTCAGATT
TCAACACTGTCTTGTCTAGTGACCAAAATACTTTGGATGGGACACATTCTCAGCATAGCACCAGTCAGGATGATGTGGCAGGTGTAGAAG
AAGCAAACCAAGGGTTTCCTGCTGTTCAGCTTGCTGATGCACAGGTTGTTTTCAAGCCTCTTCTGAGTCATACAGGGATCCAGTCACAGG
ATACAATGCCATTCTGCTACCGAATGTACTTTGGAGAACACCTTTCATTTTCAGGGACTTTGGACTGCCTCAGAGCAGATATTGTGGATT
CAGACACAGCCAAAGAGAGAAAAGGCAAAAGAGCAAGAAGGCAAGGCCATGTGAATCTTCCTCCACTTGAGTTCAAACCAGCATTAATGT
TGGGAACCTTTAGCATCAGTGCTGTTGTAATGGAAAAGTCCGTGTGCACCCCTCAGAACTCTACCAGTGCCCTTTCTTTTCATGATCTCA
GCAAGCGGTATTATAACACCTTTCACTGCAACTTTACTATTTCCTGTCAGTCAATAAGCCAGCATGTAGATATGGCTTTGGTTCGTCTTA
TTCATCAGTTTAGCACAATGATAGATGACATCAAAGCAACTCAGACTGATATTAAACTTAGCAGATATACAGCCGGATCTGCTTCCCCAA
CACCTACCTTCAAAACCAGAAAACATCGGGACTTTCGTTCATCTGACTTTAGCCGCAGTTCTAGAGGAAGTCTTAATGGTGGCAATAGAG
TAAATAATGCAAAGAACAAACGGACCAACAATGAGAATAACAAAAAGGAATCTCGAAACAAGAATTCATTAGGAAGATCTGAAAGAAGAA
CATCAAAAGTGTCTAGGAAAGGTTCAAAAGATGTGGTGGATCACATGACTATTCATATGGATGACTCTGATTCAATTACAGTGTCAGAAC
AAAGTGAGCCTTCAGCTGAGTGCTGGCAGAATATGTATAAATTGCTTAACTTCTATTCACTTATCTCCGATCCAACAGGAATATTGGAAA
AGTCTTCAGAAACATTTGGACCAGCAGGAGTTCGGAGCCCTACAGAGCCAACATGTAAAGTTGTGTTTGAGAATGAACAAGACAACAGCA
GTTTGACTAAGACTCAGAGGAAACGTAGCTTGGTAACTTCTGAACCTCAGCATGTTACTCTAATAGTGTTTGGGATTGGCATGGTGAACC
GCACACACCTAGAGGCAGATATTGGTGGACTAACAATGGAATCAGAACTGAAGAGGATCCATGGCAGTTTTACTCTTAAGGAAAAAATGA
AAGATGTTTTACATCAAAAGATGACTGAGACTTGTGCTACTGCTCATATTGGTGGGGTTAATATTGTGCTGCTTGAAGGGATTACACCAA
ATATACAACTGGAGGATTTTCCTACATCTCCTACAAGTACAGCCAAACAAGAGTTTCTAACTGTAGTGAAATGTAGTATTGCCAAGTCCC
AAGCCCTCTACAGTGCCCAAAGAGGGCTGAAGACAAACAATGCTGCTGTGTTCAAAGTAGGAGCTATCAGTATCAACATTCCTCAGCACC
CTGCCACCTTACATAGCATGATGGTTCGAAGTTCTCACCAACTATCTAAACAAATCTCAGACCTAATCAGACAGCCTTCTACAGCCCCAC
AGCCTGTAAAAGAAGATATTGCAACCCCACTACCTTCTGAAAAAACCCCAACAAGTGTTAATCAAACTCCTGTTGAAACAAATGAATTTC
CTCAGCTACCAGAAGGCTTAGAAAAGAAGCCTATTGTTCTTAAATTCAGTGCCATGTTAGATGGTATAGCCATTGGAGCAGCACTTTTAC
CATCTCTGAAAGCAGAATACAAGATGGGAAGAATGAGAAGTCATGGAATGACAGGTGCACAGACAAGATTTACATTTGAGCTGCCAAATC
ACAGATTGCGTTTTACTTCAAAAGTTTCTGCCACAGATATGTCAACCATTCCTCCTTCTGCCAGTCTTAACCTTCCCCCTGTTACCATGT
CAGGGAAATATATAATGGAAGAACATGATAGTTATTCGGATCAGGTGTGGAGTATAGATGAACTGCCTTCTAAACAAGGTTACTATTTAC
AGGGAAATTATCTGCGTTGTGTGGCAGAAGTTGGTTCCTTTGAACATAATCTTACAACTGATCTTCTAAACCACTTGGTATTTGTACAGA
AAGTGTTCATGAAGGAAGTTAATGAAGTAATACAAAAAGTTTCTGGTGGGGAGCAGCCTATTCCTCTCTGGAACGAACATGATGGAACAG
CAGATGGAGATAAACCTAAAATTCTCCTCTATTCCCTAAACTTGCAGTTCAAGGGTATTCAAGTAACGGCCACTACTCCATCAATGAGAG
CTGTAAGATTTGAAACTGGATTGATTGAACTGGAACTTTCTAACCGACTTCAAACCAAAGCTTCACCAGGAAGTAGCAGCTATCTGAAAC
TGTTTGGCAAATGCCAGGTGGATTTAAATCTGGCATTAGGACAAATTGTCAAACATCAGGTTTATGAGGAAGCTGGTTCTGATTTTCATC
AAGTTGCCTATTTTAAAACCAGAATTGGATTAAGAAATGCCCTCCGAGAAGAAATCAGTGGTTCTTCAGATAGGGAAGCTGTGCTTATTA
CTTTGAATAGACCAATTGTTTATGCACAGCCTGTGGCCTTTGATAGAGCTGTGCTGTTTTGGCTGAATTATAAGGCCGCCTATGACAACT
GGAATGAACAACGAATGGCTTTACATAAGGATATTCATATGGCTACAAAGGAAGTAGTAGATATGCTACCTGGTATCCAGCAAACATCAG
CCCAGGCCTTTGGGACTCTTTTTCTCCAGCTCACTGTCAATGATCTGGGAATTTGCCTACCTATCACAAATACTGCACAGTCTAATCATA
CTGGAGACCTTGACACTGGTTCTGCTTTGGTATTAACCATTGAAAGTACTCTCATCACTGCATGCTCTTCAGAGTCTCTGGTTAGCAAAG
GGCATTTCAAAAACTTTTGTATCCGTTTTGCTGATGGATTTGAGACATCATGGGATGACTGGAAACCAGAAATTCATGGGGATTTAGTGA
TGAATGCCTGTGTAGTTCCAGATGGCACCTATGAAGTATGTTCAAGAACTACAGGACAAGCAGCAGCTGAAAGCAGTAGTGCTGGAACCT
GGACACTCAACGTATTGTGGAAAATGTGTGGGATTGATGTTCACATGGATCCTAACATTGGCAAAAGGCTTAATGCTCTGGGCAATACTC
TTACAACACTGACAGGAGAGGAAGACATAGATGACATTGCTGACTTAAATTCAGTGAACATAGCTGACCTGTCAGATGAGGATGAAGTTG
ATACTATGTCTCCCACTATCCATACTGAAGCCACAGATTATCGAAGACAGGCAGCATCTGCTAGCCAGCCGGGAGAACTTAGAGGAAGAA
AAATTATGAAGCGTATAGTGGATATCAGAGAACTGAATGAACAGGCCAAAGTAATAGATGATCTGAAAAAATTAGGTGCAAGTGAAGGAA
CCATAAACCAGGAAATTCAACGTTACCAACAGTTAGAATCTGTGGCTGTGAATGACATTAGAAGAGATGTTCGTAAAAAATTACGGAGGT
CCAGTATGCGGGCTGCTTCCCTAAAGGATAAGTGGGGTTTGAGTTACAAACCAAGTTACAGCCGATCAAAAAGCATTTCTGCTTCTGGAA
GACCACCTCTTAAGCGAATGGAAAGGGCAAGTTCTCGAGTAGGAGAAACTGAAGAGCTCCCAGAAATCCGTGTGGATGCAGCATCTCCTG
GACCTAGAGTAACTTTTAATATCCAGGATACATTTCCAGAGGAGACAGAACTGGACCTTTTGTCAGTAACCATTGAAGGTCCATCCCATT
ATTCATCAAATAGTGAAGGATCATGTTCTGTGTTCAGTTCTCCCAAAACTCCAGGAGGCTTTTCACCAGGCATTCCTTTCCAAACTGAAG
AGGGCCGACGGGATGACAGTTTGTCTTCTACCAGTGAAGATTCCGAGAAGGATGAAAAAGATGAAGACCATGAGAGGGAAAGGTTTTATA
TTTACAGGAAACCCTCACATACGTCTCGTAAAAAAGCAACAGGCTTTGCTGCTGTTCATCAGCTATTTACAGAACGCTGGCCAACAACAC
CAGTCAATAGAAGTCTTAGTGGCACAGCTACAGAGAGAAATATTGACTTTGAACTTGATATACGGGTTGAAATTGATAGTGGAAAATGTG
TACTCCACCCAACCACCCTTCTACAAGAACATGATGATATAAGTTTGAGAAGGAGTTATGATCGAAGTTCCAGGAGCTTAGATCAAGATT
CACCTTCAAAAAAGAAGAAGTTTCAAACTAATTATGCTTCTACCACCCATTTAATGACCGGCAAGAAAGTGCCATCATCTCTACAGACAA
AGCCTAGTGACTTAGAAACAACAGTATTTTACATTCCCGGAGTTGATGTAAAGTTGCATTACAATTCCAAGACGCTAAAGACTGAATCAC
CTAATGCCTCCAGGGGATCTTCCTTGCCAAGAACACTGTCCAAAGAGTCCAAGCTGTATGGTATGAAAGATAGTGCAACATCTCCTCCTT
CTCCTCCTTTACCTTCCACTGTCCAGAGCAAGACTAACACCTTACTTCCTCCCCAGCCCCCACCTATTCCTGCAGCCAAAGGAAAAGGAA
GTGGAGGAGTAAAAACAGCCAAGTTATATGCCTGGGTAGCACTTCAGTCATTGCCAGAAGAAATGGTTATTAGTCCCTGCCTATTAGACT
TTCTGGAAAAAGCTCTGGAAACTATCCCAATTACACCAGTTGAAAGGAATTATACAGCTGTCAGCTCACAAGATGAAGATATGGGACATT
TTGAAATACCAGATCCTATGGAAGAATCAACAACATCACTAGTGTCGTCTTCAACATCTGCTTACTCTTCCTTCCCTGTAGATGTTGTGG
TTTATGTACGAGTTCAGCCCTCACAGATCAAATTTAGCTGTTTACCAGTATCAAGAGTAGAATGCATGTTAAAGCTGCCATCCCTGGATT
TGGTGTTTTCTTCAAACCGAGGAGAACTGGAGACTTTAGGGACTACATATCCTGCAGAGACTTTATCCCCTGGAGGTAATGCTACTCAGA
GTGGAACAAAGACTTCTGCTAGCAAAACTGGAATACCAGGTTCATCGGGATTAGGCAGCCCTCTTGGCCGAAGTCGACATAGTAGTAGTC
AGTCAGACCTGACCAGTTCCAGCAGTAGTTCATCTGGCTTGAGCTTCACTGCATGCATGTCTGACTTTTCCCTTTATGTATTTCATCCAT
ATGGAGCAGGGAAACAAAAAACTGCTGTTTCTGGCCTCACACCTGGATCAGGAGGATTAGGGAATGTGGATGAGGAGCCCACTTCAGTCA
CTGGTCGAAAAGATTCACTCAGTATAAACCTTGAGTTTGTAAAAGTGAGTTTGTCACGGATCAGGCGTTCAGGAGGTGCCTCATTTTTTG
AAAGTCAGTCTGTAAGCAAGTCTGCAAGCAAAATGGATACTACGTTAATAAATATATCTGCTGTTTGTGATATAGGGTCTGCCTCCTTTA
AATATGATATGCGCCGACTCAGTGAAATTCTGGCATTTCCAAGAGCATGGTATAGAAGAAGTATTGCAAGACGTCTATTCCTTGGAGACC
AAACTATAAATTTGCCAACATCTGGCCCAGGGACACCTGATTCCATTGAAGGGGTAAGCCAACACCTTTCCCCTGAATCATCAAGAAAAG
CTTACTGCAAGACCTGGGAGCAGCCAAGTCAGTCAGCCTCCTTCACCCACATGCCTCAGTCACCTAATGTGTTCAATGAGCATATGACAA
ACAGCACCATGTCACCAGGGACAGTAGGACAGAGCCTAAAATCCCCAGCTTCCATAAGATCAAGGAGTGTATCTGATTCTTCAGTTCCTC
GAAGAGATTCACTTTCAAAAACATCAACTCCTTTTAACAAATCAAACAAAGCAGCAAGCCAACAAGGGACCCCATGGGAAACACTTGTCG
TGTTTGCTATCAACTTGAAGCAATTAAACGTTCAAATGAATATGAGTAATGTAATGGGAAATACAACTTGGACAACTAGTGGTTTGAAGA
GCCAGGGCCGTCTGTCAGTAGGAAGTAATCGTGATCGAGAGATCAGCATGTCTGTTGGTCTGGGAAGATCACAATTAGATTCTAAAGGAG
GAGTAGTTGGAGGGACCATAGATGTCAATGCTTTGGAGATGGTTGCTCATATTTCTGAACATCCAAATCAGCAACCCAGTCACAAAATTC
AGATTACTATGGGTTCTACTGAAGCTCGTGTTGATTACATGGGCTCAAGTATCCTCATGGGCATCTTCAGTAATGCTGATCTTAAGCTTC
AGGATGAATGGAAAGTAAACTTGTATAATACATTGGATTCAAGCATAACTGATAAAAGTGAGATTTTCGTCCATGGAGATTTGAAGTGGG
ATATTTTCCAAGTAATGATATCAAGGTCAACCACACCAGATCTGATAAAAATAGGAATGAAGCTCCAGGAATTTTTCACACAACAATTTG
ATACCAGCAAACGAGCTCTGTCTACCTGGGGACCAGTTCCTTACCTTCCGCCAAAGACAATGACTAGCAACCTAGAAAAAAGTTCACAAG
AACAATTACTTGATGCAGCACATCATCGACACTGGCCTGGAGTATTGAAGGTGGTATCAGGATGCCACATATCCTTATTTCAGATTCCAT
TACCAGAAGATGGAATGCAATTTGGAGGATCAATGAGCTTACATGGAAATCATATGACACTGGCATGTTTTCATGGTCCAAATTTTCGTT
CAAAATCTTGGGCCCTTTTTCATTTAGAAGAACCAAATATTGCTTTTTGGACTGAAGCTCAGAAAATCTGGGAAGATGGCTCCAGTGATC
ATTCTACATATATTGTACAAACACTAGATTTTCACCTGGGTCATAATACTATGGTTACCAAACCATGTGGTGCTTTGGAAAGTCCTATGG
CAACAATAACCAAGATAACAAGGCGTCGCCATGAAAATCCACCCCATGGAGTAGCAAGTGTGAAAGAATGGTTCAATTATGTTACAGCTA
CAAGGAATGAAGAGCTAAATCTGCTTCGTAATGTTGATGCTAACAACACTGAGAATAGCACTACTGTGAAGAATTCTAGTTTGTTGAGTG
GATTCAGAGGAGGTTCTAGCTACAACCATGAAACAGAGACTATCTTTGCATTACCAAGGATGCAGCTTGACTTTAAATCCATTCATGTTC
AAGAACCACAGGAGCCTTCATTACAGGATGCCAGCCTGAAGCCAAAAGTAGAATGTAGTGTGGTGACAGAGTTCACTGACCACATTTGTG
TGACTATGGATGCTGAGCTCATCATGTTTCTTCATGATTTAGTATCAGCTTATCTTAAAGAAAAAGAAAAAGCCATCTTTCCACCTCGGA
TTTTATCTACTCGACCAGGACAAAAAAGTCCAATTATTATACATGACGACAATTCCTCTGATAAAGATAGAGAAGATAGCATCACTTATA
CTACTGTGGACTGGAGAGATTTTATGTGCAATACATGGCATCTAGAACCTACTCTTAGATTAATTTCTTGGACTGGAAGAAAGATTGATC
CAGTAGGTGTTGATTATATTCTTCAAAAATTGGGCTTTCATCATGCTAGGACTACTATTCCTAAATGGCTTCAAAGAGGAGTCATGGATC
CACTGGACAAGGTTCTGTCAGTTCTTATCAAAAAGCTCGGTACTGCACTACAGGATGAAAAGGAAAAGAAAGGCAAAGACAAAGAAGAAC
ACTAAAAAAGTAATTTGATCTGTGAACAAATTATGATTGTGTCTGTTTTATTACACTGGAGTGTTTTTTTAGTATAATAATTTGAAATAT
AACTTTAAAATAATTCTAAATTTGTGGCTATAATTAAAAGTTTGTAAGTTAACCTGTTCTAGTTCCATCATTCTGTGTACAGTGAAGTAT
TGCATGATAATGTAAATTTTGTGAAAAACTAGATTAAAATATATAACTGCTTGTTATGGTTTATAATTATATAATGTGCAATACAATTCC
TGCATCTTTAAAATGTCTGCAGAATAACTGTGAATTTTTTTGTTATTGGATTGGCCGTAACTTTTAGAAAAAAATCTTGTTGATGATAAT
GTGATTTTGGGGAGGTCATTAATTGCTTTTTCTTTTTTAAATGTAGACTTATATAAATACCTGTTTGTATATAGCTTGAGTAATTGTGAT
ATGATTGTATACCACTAAAATATTGTTAACTATTATAATAAAGTCACAGTAATGGTTTAAGTCTGT

>10454_10454_5_BTBD2-KIAA1109_BTBD2_chr19_1990003_ENST00000255608_KIAA1109_chr4_123107191_ENST00000388738_length(amino acids)=5215AA_BP=329
MAAGGSGGRASCPPGVGVGPGTGGSPGPSANAAATPAPGNAAAAAAAAAAAAAAPGPTPPAPPGPGTDAQAAGAERAEEAAGPGAAALQR
EAAYNWQASKPTVQERFAFLFNNEVLCDVHFLVGKGLSSQRIPAHRFVLAVGSAVFDAMFNGGMATTSTEIELPDVEPAAFLALLKFLYS
DEVQIGPETVMTTLYTAKKYAVPALEAHCVEFLKKNLRADNAFMLLTQARLFDEPQLASLCLENIDKNTADAITAEGFTDIDLDTLVAVL
ERDTLGIREVRLFNAVVRWSEAECQRQQLQVTPENRRKVLGKALGLIRFPLMTIEEFAADPKAETRLYITVNDFEFHVYNRSDLYGRLQE
LFGLEPTIIPPKKDDDKTREIGRTRTQSKIERVKVKTESQDPTSSWRSLIPVIKVNVSTGRLAFGNHYQPQTLCINFDDAFLTYTTKPPS
SHLDQFMHIVKGKLENVRVMLVPSPRYVGLQNDEPPRLMGEGFVVMQSNDVDIYYYMDEPGLVPEETEENIEGEMSSEDCKLQDLPPCWG
LDIVCGKGTDFNYGPWADRQRDCLWKFFFPPDYQVLKVSEIAQPGRPRQILAFELRMNIIADATIDLLFTKNRETNAVHVNVGAGSYLEI
NIPMTVEENGYTPAIKGQLLHVDATTSMQYRTLLEAEMLAFHINASYPRIWNMPQTWQCELEVYKATYHFIFAQKNFFTDLIQDWSSDSP
PDIFSFVPYTWNFKIMFHQFEMIWAANQHNWIDCSTKQQENVYLAACGETLNIDFSLPFTDFVPATCNTKFSLRGEDVDLHLFLPDCHPS
KYSLFMLVKNCHPNKMIHDTGIPAECQSGQKTVKPKWRNVTQEKSGWVECWTVPSVMLTIDYTWHPIYPQKADEQLKQSLSEMEETMLSV
LRPSQKTSDRVVSSPSTSSRPPIDPSELPPDKLHVEMELSPDSQITLYGPLLNAFLCIKENYFGEDDMYMDFEEVISSPVLSLSTSSSSG
WTAVGMENDKKENEGSAKSIHPLALRPWDITVLVNLYKVHGRLPVHGTTDGPECPTAFLERLCFEMKKGFRETMLQLILSPLNVFVSDNY
QQRPPVDEVLREGHINLSGLQLRAHAMFSAEGLPLGSDSLEYAWLIDVQAGSLTAKVTAPQLACLLEWGQTFVFHVVCREYELERPKSVI
ICQHGIDRRFCESKLSCIPGPCPTSDDLKYTMIRLAVDGADIYIVEHGCATNIKMGAIRVANCNLHNQSVGEGISAAIQDFQVRQYIEQL
NNCRIGLQPAVLRRAYWLEAGSANLGLITVDIALAADHHSKHEAQRHFLETHDARTKRLWFLWPDDILKNKRCRNKCGCLGGCRFFGGTV
TGLDFFKLEELTPSSSSAFSSTSAESDMYYGQSLLQPGEWIITKEIPKIIDGNVNGMKRKEWENKSVGIEVERKTQHLSLQVPLRSHSSS
SSSEENSSSSAAQPLLAGEKESPSSVADDHLVQKEFLHGTKRDDGQASIPTEISGNSPVSPNTQDKSVGQSPLRSPLKRQASVCSTRLGS
TKSLTAAFYGDKQPVTVGVQFSSDVSRSDENVLDSPKQRRSFGSFPYTPSADSNSFHQYRSMDSSMSMADSEAYFSAAEEFEPISSDEGP
GTYPGRKKKKKQTQQIDYSRGSIYHSVEGPLTGHGESIQDSRTLPFKTHPSQASFVSALGGEDDVIEHLYIVEGEKTVESEQITPQQPVM
NCYQTYLTQFQVINWSVKHPTNKRTSKSSLHRPLDLDTPTSEESSSSFEQLSVPTFKVIKQGLTANSLLDRGMQLSGSTSNTPYTPLEKK
LADNTDDETLTEEWTLDQPVSQTRTTAIVEVKGTVDIVLTPLVAEALDRYIEAMVHCASTRHPAAIVDDLHAKVLREAVQNSKTTFSENL
SSKQDIRGTKTEQSTIGTTNQGQAQTNLTMKQDNVTIKGLQTNVSIPKVNLCLLQASVEESPTTAPSRSVTHVSLVALCFDRIATQVRMN
RGVVEETSNNAEPGRTSNFDRYVHATKMQPQSSGSLRSNAGAEKGKEIAAKLNIHRVHGQLRGLDTTDIGTCAITAIPFEKSKVLFTLEE
LDEFTFVDETDQQAVPDVTRIGPSQEKWGWIMFECGLENLTIKGGRQSGAVLYNSFGIMGKASDTERGGVLTSNNSSDSPTGSGYNTDVS
DDNLPCDRTSPSSDLNGNSVSDEQDEGVESDDLKKDLPLMPPPPDSCSMKLTIKEIWFSFAAPTNVRSHTHAFSRQLNLLSTATPAVGAW
LVPIDQLKSSLNKLETEGTLRICAVMGCIMTEALENKSVHFPLRSKYNRLTKVARFLQENPSCLLCNILHHYLHQANYSIIDDATMSDGL
PALVTLKKGLVALARQWMKFIVVTPAFKGVSLHRPAQPLKPQIAMDHEHEDGLGLDNGGGLQSDTSADGAEFEFDAATVSEHTMLLEGTA
NRPPPGSSGPVTGAEIMRKLSKTHTHSDSALKIKGIHPYHSLSYTSGDTATDSPVHVGRAGMPVKDSPRKESLLSYLTGSFPSLHNLLEG
TPQRSSAAVKSSSLTRTGNTVATDMLSEHPLLSEPSSVSFYNWMSNAVGNRGSVLQESPVTKSGHNSLPTGVAPNLPTIPSASDFNTVLS
SDQNTLDGTHSQHSTSQDDVAGVEEANQGFPAVQLADAQVVFKPLLSHTGIQSQDTMPFCYRMYFGEHLSFSGTLDCLRADIVDSDTAKE
RKGKRARRQGHVNLPPLEFKPALMLGTFSISAVVMEKSVCTPQNSTSALSFHDLSKRYYNTFHCNFTISCQSISQHVDMALVRLIHQFST
MIDDIKATQTDIKLSRYTAGSASPTPTFKTRKHRDFRSSDFSRSSRGSLNGGNRVNNAKNKRTNNENNKKESRNKNSLGRSERRTSKVSR
KGSKDVVDHMTIHMDDSDSITVSEQSEPSAECWQNMYKLLNFYSLISDPTGILEKSSETFGPAGVRSPTEPTCKVVFENEQDNSSLTKTQ
RKRSLVTSEPQHVTLIVFGIGMVNRTHLEADIGGLTMESELKRIHGSFTLKEKMKDVLHQKMTETCATAHIGGVNIVLLEGITPNIQLED
FPTSPTSTAKQEFLTVVKCSIAKSQALYSAQRGLKTNNAAVFKVGAISINIPQHPATLHSMMVRSSHQLSKQISDLIRQPSTAPQPVKED
IATPLPSEKTPTSVNQTPVETNEFPQLPEGLEKKPIVLKFSAMLDGIAIGAALLPSLKAEYKMGRMRSHGMTGAQTRFTFELPNHRLRFT
SKVSATDMSTIPPSASLNLPPVTMSGKYIMEEHDSYSDQVWSIDELPSKQGYYLQGNYLRCVAEVGSFEHNLTTDLLNHLVFVQKVFMKE
VNEVIQKVSGGEQPIPLWNEHDGTADGDKPKILLYSLNLQFKGIQVTATTPSMRAVRFETGLIELELSNRLQTKASPGSSSYLKLFGKCQ
VDLNLALGQIVKHQVYEEAGSDFHQVAYFKTRIGLRNALREEISGSSDREAVLITLNRPIVYAQPVAFDRAVLFWLNYKAAYDNWNEQRM
ALHKDIHMATKEVVDMLPGIQQTSAQAFGTLFLQLTVNDLGICLPITNTAQSNHTGDLDTGSALVLTIESTLITACSSESLVSKGHFKNF
CIRFADGFETSWDDWKPEIHGDLVMNACVVPDGTYEVCSRTTGQAAAESSSAGTWTLNVLWKMCGIDVHMDPNIGKRLNALGNTLTTLTG
EEDIDDIADLNSVNIADLSDEDEVDTMSPTIHTEATDYRRQAASASQPGELRGRKIMKRIVDIRELNEQAKVIDDLKKLGASEGTINQEI
QRYQQLESVAVNDIRRDVRKKLRRSSMRAASLKDKWGLSYKPSYSRSKSISASGRPPLKRMERASSRVGETEELPEIRVDAASPGPRVTF
NIQDTFPEETELDLLSVTIEGPSHYSSNSEGSCSVFSSPKTPGGFSPGIPFQTEEGRRDDSLSSTSEDSEKDEKDEDHERERFYIYRKPS
HTSRKKATGFAAVHQLFTERWPTTPVNRSLSGTATERNIDFELDIRVEIDSGKCVLHPTTLLQEHDDISLRRSYDRSSRSLDQDSPSKKK
KFQTNYASTTHLMTGKKVPSSLQTKPSDLETTVFYIPGVDVKLHYNSKTLKTESPNASRGSSLPRTLSKESKLYGMKDSATSPPSPPLPS
TVQSKTNTLLPPQPPPIPAAKGKGSGGVKTAKLYAWVALQSLPEEMVISPCLLDFLEKALETIPITPVERNYTAVSSQDEDMGHFEIPDP
MEESTTSLVSSSTSAYSSFPVDVVVYVRVQPSQIKFSCLPVSRVECMLKLPSLDLVFSSNRGELETLGTTYPAETLSPGGNATQSGTKTS
ASKTGIPGSSGLGSPLGRSRHSSSQSDLTSSSSSSSGLSFTACMSDFSLYVFHPYGAGKQKTAVSGLTPGSGGLGNVDEEPTSVTGRKDS
LSINLEFVKVSLSRIRRSGGASFFESQSVSKSASKMDTTLINISAVCDIGSASFKYDMRRLSEILAFPRAWYRRSIARRLFLGDQTINLP
TSGPGTPDSIEGVSQHLSPESSRKAYCKTWEQPSQSASFTHMPQSPNVFNEHMTNSTMSPGTVGQSLKSPASIRSRSVSDSSVPRRDSLS
KTSTPFNKSNKAASQQGTPWETLVVFAINLKQLNVQMNMSNVMGNTTWTTSGLKSQGRLSVGSNRDREISMSVGLGRSQLDSKGGVVGGT
IDVNALEMVAHISEHPNQQPSHKIQITMGSTEARVDYMGSSILMGIFSNADLKLQDEWKVNLYNTLDSSITDKSEIFVHGDLKWDIFQVM
ISRSTTPDLIKIGMKLQEFFTQQFDTSKRALSTWGPVPYLPPKTMTSNLEKSSQEQLLDAAHHRHWPGVLKVVSGCHISLFQIPLPEDGM
QFGGSMSLHGNHMTLACFHGPNFRSKSWALFHLEEPNIAFWTEAQKIWEDGSSDHSTYIVQTLDFHLGHNTMVTKPCGALESPMATITKI
TRRRHENPPHGVASVKEWFNYVTATRNEELNLLRNVDANNTENSTTVKNSSLLSGFRGGSSYNHETETIFALPRMQLDFKSIHVQEPQEP
SLQDASLKPKVECSVVTEFTDHICVTMDAELIMFLHDLVSAYLKEKEKAIFPPRILSTRPGQKSPIIIHDDNSSDKDREDSITYTTVDWR
DFMCNTWHLEPTLRLISWTGRKIDPVGVDYILQKLGFHHARTTIPKWLQRGVMDPLDKVLSVLIKKLGTALQDEKEKKGKDKEEH

--------------------------------------------------------------
>10454_10454_6_BTBD2-KIAA1109_BTBD2_chr19_1990003_ENST00000255608_KIAA1109_chr4_123107191_ENST00000455637_length(transcript)=11690nt_BP=1005nt
CACGCCGCAGCCACAAAATGGCGGCGGGTGGGAGCGGCGGGCGTGCGTCGTGCCCGCCGGGGGTCGGGGTCGGCCCGGGCACGGGGGGCA
GTCCCGGGCCCAGCGCCAACGCCGCCGCCACCCCGGCCCCCGGCAACGCGGCCGCCGCCGCCGCCGCCGCCGCCGCCGCCGCCGCCGCCC
CTGGGCCGACGCCGCCCGCCCCGCCGGGCCCCGGGACAGACGCGCAGGCCGCGGGCGCGGAGCGGGCGGAGGAGGCGGCGGGCCCGGGGG
CGGCGGCGCTGCAGCGCGAGGCCGCGTACAACTGGCAGGCCAGCAAGCCCACCGTGCAGGAGCGCTTCGCCTTCCTCTTCAACAACGAGG
TGCTGTGCGACGTGCACTTCCTGGTGGGCAAGGGGCTCAGCTCGCAGCGCATCCCCGCGCACAGGTTCGTGCTGGCCGTGGGCAGCGCCG
TCTTTGATGCCATGTTCAACGGGGGAATGGCCACAACATCCACGGAGATTGAGCTGCCCGACGTGGAACCCGCTGCCTTCCTCGCACTGC
TCAAGTTTCTCTACTCGGACGAGGTGCAGATTGGCCCGGAGACGGTGATGACCACGCTATACACCGCCAAGAAGTACGCGGTGCCAGCGC
TCGAGGCCCATTGCGTGGAGTTCCTGAAGAAGAACCTGCGAGCCGACAACGCCTTCATGCTGCTCACGCAGGCGCGACTCTTCGATGAAC
CGCAGCTGGCCAGCCTGTGCCTGGAGAACATCGACAAAAACACTGCAGACGCCATCACCGCGGAGGGCTTCACCGACATTGACCTGGACA
CGCTGGTGGCTGTCCTGGAGCGCGACACACTGGGCATCCGTGAGGTGCGGCTGTTCAATGCCGTTGTCCGCTGGTCCGAGGCCGAGTGTC
AGCGGCAGCAGCTGCAGGTGACGCCAGAGAACAGGCGGAAGGTTCTGGGCAAGGCCCTGGGCCTCATTCGCTTCCCGCTCATGACCATCG
AGGAGTTCGCTGCAGATCCAAAGGCAGAAACCAGGTTATACATCACAGTCAATGACTTTGAATTTCATGTCTATAATCGCTCGGATCTTT
ATGGACGCCTTCAAGAGTTGTTTGGTTTGGAGCCAACAATAATTCCACCTAAGAAAGATGATGATAAAACACGGGAAATTGGAAGAACAA
GAACCCAATCGAAAATTGAAAGAGTTAAAGTAAAAACAGAATCCCAAGACCCCACATCTTCATGGAGATCACTTATTCCAGTCATAAAGG
TCAATGTGAGCACAGGACGTTTGGCCTTTGGAAATCACTACCAGCCGCAAACTCTGTGCATCAACTTTGATGATGCTTTCTTAACTTATA
CTACAAAACCACCTTCAAGTCATCTTGACCAATTCATGCATATTGTGAAAGGAAAGCTTGAAAATGTTCGAGTCATGCTTGTTCCTAGTC
CAAGATATGTTGGTCTTCAAAATGATGAACCACCGAGATTAATGGGAGAAGGTTTTGTGGTGATGCAGTCAAATGATGTTGACATCTACT
ACTACATGGATGAGCCAGGACTTGTTCCGGAAGAAACAGAAGAAAATATTGAAGGAGAAATGAGCAGTGAGGATTGCAAATTACAAGACT
TGCCTCCATGTTGGGGACTGGATATAGTTTGTGGTAAAGGAACAGATTTTAATTATGGACCATGGGCCGATAGGCAGAGAGATTGTTTGT
GGAAGTTTTTCTTTCCACCTGACTATCAAGTTCTGAAAGTTTCTGAAATTGCACAGCCTGGGAGACCAAGACAGATCCTTGCTTTTGAAT
TACGAATGAATATTATTGCAGATGCTACAATTGATTTGCTGTTTACCAAAAATAGGGAAACAAATGCTGTACATGTAAATGTAGGAGCTG
GCTCATATTTAGAAATTAATATTCCAATGACAGTTGAAGAAAATGGTTACACTCCTGCTATTAAGGGACAACTCTTACATGTGGATGCCA
CTACCAGCATGCAATATCGGACCCTTTTAGAAGCAGAAATGTTAGCATTCCACATCAATGCCAGCTACCCCCGAATATGGAACATGCCGC
AGACATGGCAGTGTGAATTAGAGGTTTATAAAGCCACTTACCACTTCATCTTTGCACAGAAAAACTTCTTTACAGATTTAATTCAAGACT
GGTCTAGTGACAGTCCTCCAGACATTTTTTCATTTGTTCCATATACGTGGAATTTTAAAATCATGTTTCATCAGTTTGAAATGATTTGGG
CTGCTAATCAACACAATTGGATCGACTGTTCTACTAAACAACAGGAAAATGTGTATCTGGCAGCCTGTGGAGAAACACTAAACATTGATT
TTTCTTTGCCTTTTACGGACTTTGTTCCAGCTACATGTAATACCAAGTTCTCTTTAAGAGGAGAAGATGTTGATCTTCATTTGTTTCTAC
CAGACTGCCACCCTAGTAAATATTCTTTATTTATGCTGGTAAAAAATTGCCATCCAAATAAGATGATTCATGATACTGGTATTCCTGCTG
AGTGTCAAAGTGGCCAGAAAACAGTTAAACCAAAATGGCGCAACGTTACTCAGGAAAAGTCTGGTTGGGTTGAATGCTGGACTGTCCCAA
GTGTCATGCTTACAATTGATTATACATGGCATCCAATTTATCCACAAAAAGCAGATGAACAGCTGAAACAATCATTATCAGAAATGGAAG
AGACAATGCTATCTGTATTAAGGCCATCCCAGAAGACATCAGACAGAGTTGTTTCTTCTCCCTCTACTTCTTCACGCCCACCTATTGATC
CCTCAGAACTTCCACCTGATAAACTTCATGTAGAAATGGAACTTTCTCCAGATTCTCAGATAACTCTCTATGGACCTCTACTAAATGCCT
TTTTGTGTATAAAGGAAAACTACTTTGGGGAAGATGACATGTATATGGATTTTGAAGAGGTTATCTCAAGTCCTGTTTTGTCACTGTCAA
CATCATCCAGCTCTGGGTGGACTGCTGTTGGAATGGAAAATGACAAAAAGGAAAATGAAGGTTCAGCCAAGTCAATTCATCCACTTGCCT
TGCGTCCTTGGGATATTACTGTACTTGTTAATTTGTACAAAGTTCATGGGCGTCTTCCTGTTCATGGAACTACTGATGGTCCTGAATGCC
CTACAGCTTTCTTGGAAAGACTATGTTTTGAAATGAAAAAAGGATTTAGGGAGACCATGCTGCAACTTATCCTGTCACCCCTGAATGTGT
TTGTCAGTGATAACTATCAGCAGCGACCCCCTGTGGATGAAGTACTCAGGGAAGGTCACATCAATTTGTCAGGTCTCCAGCTGAGAGCAC
ACGCTATGTTCTCAGCAGAAGGTCTTCCTTTGGGAAGCGATTCCTTAGAATACGCATGGTTAATTGATGTGCAGGCTGGAAGTCTTACAG
CTAAGGTCACAGCACCACAGCTGGCATGCCTCTTGGAGTGGGGACAGACATTTGTTTTTCATGTGGTATGTCGGGAGTATGAACTGGAAA
GACCGAAATCAGTTATAATATGTCAGCATGGAATTGATCGTCGGTTCTGTGAATCCAAGTTGAGTTGTATTCCTGGGCCTTGTCCAACTT
CAGATGATTTGAAATATACTATGATTCGTTTAGCAGTAGATGGAGCCGATATTTACATTGTTGAGCATGGTTGTGCTACAAATATAAAGA
TGGGTGCAATTCGAGTTGCAAACTGTAATCTCCACAATCAATCGGTTGGGGAAGGAATCAGTGCTGCAATTCAGGATTTTCAAGTGAGAC
AGTACATTGAGCAATTAAATAATTGCAGAATTGGACTTCAGCCTGCAGTGCTACGGAGGGCCTATTGGCTTGAAGCTGGGTCAGCCAATT
TAGGACTTATTACTGTTGATATTGCTTTAGCTGCTGACCATCATTCTAAACATGAGGCACAAAGACATTTCTTAGAAACTCATGATGCCA
GAACTAAGAGGTTGTGGTTTTTATGGCCAGATGATATCCTGAAGAATAAGAGGTGTAGAAACAAATGTGGTTGTCTCGGTGGCTGCAGAT
TCTTTGGTGGCACAGTAACTGGCCTAGATTTCTTCAAACTTGAAGAGTTGACACCTTCCAGTAGCTCTGCATTTTCAAGCACAAGTGCAG
AGTCTGATATGTATTATGGACAGTCTCTGCTACAGCCTGGAGAATGGATAATTACTAAAGAAATTCCCAAAATTATAGATGGTAATGTGA
ATGGCATGAAGAGGAAAGAATGGGAAAACAAATCAGTGGGAATAGAAGTAGAGAGAAAAACTCAGCACCTTAGTCTTCAAGTACCATTAC
GATCTCATAGTTCATCCTCTTCCTCAGAAGAGAACAGTAGTTCTAGTGCTGCACAGCCTTTGTTGGCTGGTGAAAAGGAAAGTCCTTCAT
CTGTTGCTGATGACCATTTGGTTCAAAAAGAGTTCTTGCATGGGACAAAAAGAGATGATGGCCAAGCAAGTATCCCTACAGAAATTTCAG
GAAACAGCCCTGTGTCTCCTAATACTCAGGATAAGTCAGTAGGTCAATCTCCTCTTAGATCTCCCTTGAAACGACAAGCCTCTGTCTGTT
CCACCCGTCTTGGAAGTACTAAGAGTCTTACTGCTGCTTTCTATGGGGACAAGCAGCCTGTAACAGTTGGAGTCCAGTTTAGTAGTGATG
TCTCTCGAAGTGATGAGAATGTACTAGACTCACCAAAGCAGAGGAGAAGTTTTGGTTCATTCCCATATACACCATCAGCAGACTCTAATT
CATTTCATCAGTATCGATCAATGGATTCCAGCATGTCAATGGCTGATAGTGAAGCCTACTTTTCTGCTGCTGAGGAATTTGAGCCCATTA
GCAGTGATGAAGGCCCTGGAACTTATCCGGGTAGAAAAAAGAAGAAAAAGCAAACCCAGCAGATTGACTACAGTAGGGGTTCCATATATC
ACAGTGTAGAAGGGCCACTTACTGGACATGGAGAAAGCATTCAGGATTCCAGAACTCTGCCATTCAAAACTCATCCTTCTCAGGCTTCAT
TTGTTTCTGCGTTAGGTGGAGAAGATGATGTTATAGAACATCTATATATTGTAGAAGGTGAGAAAACAGTGGAGAGTGAACAGATTACTC
CGCAACAACCCGTGATGAATTGTTATCAGACTTACCTTACTCAGTTCCAGGTAATTAATTGGTCAGTTAAGCACCCAACCAACAAAAGAA
CCTCTAAATCCTCATTGCATCGTCCCCTTGATCTGGATACACCAACCAGTGAAGAAAGTTCATCGTCATTTGAACAGCTTTCTGTTCCAA
CTTTTAAGGTTATCAAGCAGGGGCTCACAGCTAATTCTTTGCTAGACAGAGGCATGCAACTTTCAGGATCAACTTCAAATACGCCGTATA
CTCCATTGGAAAAAAAACTCGCTGATAACACAGATGATGAAACATTAACAGAAGAGTGGACCCTGGATCAACCAGTGTCCCAGACCAGGA
CAACAGCCATAGTTGAAGTAAAAGGAACTGTTGATATTGTTTTGACTCCCCTGGTGGCTGAAGCTTTAGACAGATATATTGAAGCAATGG
TTCATTGTGCTAGTACCCGACATCCAGCTGCAATTGTAGATGATCTTCATGCTAAAGTCCTCAGGGAAGCTGTCCAAAATAGCAAGACTA
CCTTTTCAGAAAATTTATCTTCCAAACAAGACATTAGAGGAACAAAAACTGAGCAGTCTACAATAGGAACGACTAACCAAGGACAAGCAC
AGACAAATCTTACAATGAAGCAAGATAATGTAACAATTAAAGGTCTTCAGACTAATGTTAGCATACCAAAGGTAAACTTATGTTTGTTAC
AAGCCTCAGTGGAAGAATCTCCAACTACGGCTCCTAGTAGGAGTGTGACTCATGTTTCCCTAGTGGCATTGTGTTTTGACAGAATTGCTA
CACAGGTTCGCATGAACAGAGGTGTGGTTGAAGAGACTTCAAACAATGCAGAACCTGGTAGAACATCAAATTTTGATAGGTATGTTCATG
CCACAAAGATGCAGCCTCAGTCATCTGGATCTCTCAGATCAAATGCTGGAGCAGAAAAAGGCAAAGAAATTGCAGCTAAGTTAAACATTC
ATCGAGTTCATGGGCAACTTAGGGGTCTTGATACAACAGACATTGGGACCTGTGCAATCACTGCTATTCCTTTTGAGAAGTCCAAAGTTT
TATTTACTCTTGAAGAGTTGGATGAATTTACTTTTGTGGATGAAACTGATCAGCAAGCTGTTCCAGATGTAACTCGAATAGGTCCCAGCC
AAGAAAAATGGGGATGGATAATGTTTGAATGTGGACTTGAAAATTTAACCATAAAAGGAGGAAGACAGTCTGGTGCTGTTTTATATAACA
GTTTTGGAATTATGGGTAAAGCTAGTGACACAGAAAGGGGTGGAGTGCTGACATCCAATAATTCTTCTGATTCTCCAACCGGCAGTGGCT
ATAATACTGATGTCTCTGATGATAATCTTCCATGTGACCGGACAAGCCCTTCCTCAGACTTAAATGGAAATTCTGTTTCAGATGAACAGG
ATGAAGGAGTCGAATCTGATGATTTGAAAAAAGATCTACCTCTGATGCCTCCTCCTCCAGATTCATGTAGCATGAAGTTGACCATTAAAG
AAATTTGGTTTAGTTTTGCAGCTCCCACCAATGTGAGATCTCACACACATGCATTTTCTAGGCAGCTGAACCTTTTAAGCACTGCAACAC
CAGCTGTTGGTGCATGGCTTGTTCCCATTGACCAACTCAAGTCATCTTTAAACAAATTGGAAACTGAGGGAACCTTGAGAATTTGTGCTG
TTATGGGATGCATAATGACAGAAGCATTAGAGAATAAAAGTGTACATTTTCCCCTAAGAAGTAAATACAACAGGCTTACAAAAGTTGCTC
GCTTTCTCCAAGAAAATCCTTCATGTTTACTATGTAATATACTACACCACTATCTGCACCAGGCAAATTACTCCATCATTGATGATGCTA
CAATGAGCGATGGACTTCCTGCTTTGGTAACTTTGAAGAAAGGTTTAGTTGCACTGGCAAGGCAGTGGATGAAGTTTATTGTGGTGACAC
CAGCCTTTAAAGGAGTTAGCTTACATAGACCAGCTCAGCCTCTGAAACCTCAAATAGCTATGGACCATGAACATGAAGATGGACTTGGAT
TGGACAATGGGGGTGGTCTTCAAAGTGATACCAGTGCTGATGGAGCAGAATTTGAGTTCGATGCAGCCACAGTCAGTGAACACACAATGC
TATTAGAAGGAACAGCTAACCGGCCTCCACCTGGTAGCTCTGGACCTGTAACTGGAGCTGAGATAATGAGGAAACTTTCTAAAACTCATA
CCCATAGTGACTCTGCATTAAAAATAAAGGGCATTCACCCATATCATTCTCTGAGCTATACCAGTGGAGACACTGCCACTGATTCTCCAG
TGCATGTTGGACGTGCTGGGATGCCAGTAAAGGACAGTCCAAGGAAGGAGAGCCTACTCAGCTACCTGACTGGAAGCTTCCCAAGCCTGC
ACAACCTCCTGGAAGGTACTCCTCAGAGAAGCAGTGCTGCTGTGAAAAGTAGCTCCCTAACGAGAACAGGAAATACAGTAGCCACTGATA
TGTTATCTGAACATCCCTTGCTATCTGAGCCATCATCTGTGAGTTTCTATAATTGGATGTCAAATGCTGTGGGTAATCGAGGAAGTGTGT
TACAAGAATCTCCTGTTACAAAATCAGGACACAATAGTCTTCCCACAGGTGTTGCACCCAATCTTCCAACAATACCCTCAGCCTCAGATT
TCAACACTGTCTTGTCTAGTGACCAAAATACTTTGGATGGGACACATTCTCAGCATAGCACCAGTCAGGATGATGTGGCAGGTGTAGAAG
AAGCAAACCAAGGGTTTCCTGCTGTTCAGCTTGCTGATGCACAGGTTGTTTTCAAGCCTCTTCTGAGTCATACAGGGATCCAGTCACAGG
ATACAATGCCATTCTGCTACCGAATGTACTTTGGAGAACACCTTTCATTTTCAGGGACTTTGGACTGCCTCAGAGCAGATATTGTGGATT
CAGACACAGCCAAAGAGAGAAAAGGCAAAAGAGCAAGAAGGCAAGGCCATGTGAATCTTCCTCCACTTGAGTTCAAACCAGCATTAATGT
TGGGAACCTTTAGCATCAGTGCTGTTGTAATGGAAAAGTCCGTGTGCACCCCTCAGAACTCTACCAGTGCCCTTTCTTTTCATGATCTCA
GCAAGCGGTATTATAACACCTTTCACTGCAACTTTACTATTTCCTGTCAGTCAATAAGCCAGCATGTAGATATGGCTTTGGTTCGTCTTA
TTCATCAGTTTAGCACAATGATAGATGACATCAAAGCAACTCAGACTGATATTAAACTTAGCAGATATACAGCCGGATCTGCTTCCCCAA
CACCTACCTTCAAAACCAGAAAACATCGGGACTTTCGTTCATCTGACTTTAGCCGCAGTTCTAGAGGAAGTCTTAATGGTGGCAATAGAG
TAAATAATGCAAAGAACAAACGGACCAACAATGAGAATAACAAAAAGGAATCTCGAAACAAGAATTCATTAGGAAGATCTGAAAGAAGAA
CATCAAAAGTGTCTAGGAAAGGTTCAAAAGATGTGGTGGATCACATGACTATTCATATGGATGACTCTGATTCAATTACAGTGTCAGAAC
AAAGTGAGCCTTCAGCTGAGTGCTGGCAGAATATGTATAAATTGCTTAACTTCTATTCACTTATCTCCGATCCAACAGGAATATTGGAAA
AGTCTTCAGAAACATTTGGACCAGCAGGAGTTCGGAGCCCTACAGAGCCAACATGTAAAGTTGTGTTTGAGAATGAACAAGACAACAGCA
GTTTGACTAAGACTCAGAGGAAACGTAGCTTGGTAACTTCTGAACCTCAGCATGTTACTCTAATAGTGTTTGGGATTGGCATGGTGAACC
GCACACACCTAGAGGCAGATATTGGTGGACTAACAATGGAATCAGAACTGAAGAGGATCCATGGCAGTTTTACTCTTAAGGAAAAAATGA
AAGATGTTTTACATCAAAAGATGACTGAGACTTGTGCTACTGCTCATATTGGTGGGGTTAATATTGTGCTGCTTGAAGGGATTACACCAA
ATATACAACTGGAGGATTTTCCTACATCTCCTACAAGTACAGCCAAACAAGAGTTTCTAACTGTAGTGAAATGTAGTATTGCCAAGTCCC
AAGCCCTCTACAGTGCCCAAAGAGGGCTGAAGACAAACAATGCTGCTGTGTTCAAAGTAGGAGCTATCAGTATCAACATTCCTCAGCACC
CTGCCACCTTACATAGCATGATGGTTCGAAGTTCTCACCAACTATCTAAACAAATCTCAGACCTAATCAGACAGCCTTCTACAGCCCCAC
AGCCTGTAAAAGAAGATATTGCAACCCCACTACCTTCTGAAAAAACCCCAACAAGTGTTAATCAAACTCCTGTTGAAACAAATGAATTTC
CTCAGCTACCAGAAGGCTTAGAAAAGAAGCCTATTGTTCTTAAATTCAGTGCCATGTTAGATGGTATAGCCATTGGAGCAGCACTTTTAC
CATCTCTGAAAGCAGAATACAAGATGGGAAGAATGAGAAGTCATGGAATGACAGGTGCACAGACAAGATTTACATTTGAGCTGCCAAATC
ACAGATTGCGTTTTACTTCAAAAGTTTCTGCCACAGATATGTCAACCATTCCTCCTTCTGCCAGTCTTAACCTTCCCCCTGTTACCATGT
CAGGGAAATATATAATGGAAGAACATGATAGTTATTCGGATCAGGTGTGGAGTATAGATGAACTGCCTTCTAAACAAGGTTACTATTTAC
AGGGAAATTATCTGCGTTGTGTGGCAGAAGTTGGTTCCTTTGAACATAATCTTACAACTGATCTTCTAAACCACTTGGTATTTGTACAGA
AAGTGTTCATGAAGGAAGTTAATGAAGTAATACAAAAAGTTTCTGGTGGGGAGCAGCCTATTCCTCTCTGGAACGAACATGATGGAACAG
CAGATGGAGATAAACCTAAAATTCTCCTCTATTCCCTAAACTTGCAGTTCAAGGGTATTCAAGTAACGGCCACTACTCCATCAATGAGAG
CTGTAAGATTTGAAACTGGATTGATTGAACTGGAACTTTCTAACCGACTTCAAACCAAAGCTTCACCAGGAAGTAGCAGCTATCTGAAAC
TGTTTGGCAAATGCCAGGTGGATTTAAATCTGGCATTAGGACAAATTGTCAAACATCAGGTTTATGAGGAAGCTGGTTCTGATTTTCATC
AAGTTGCCTATTTTAAAACCAGAATTGGATTAAGAAATGCCCTCCGAGAAGAAATCAGTGGTTCTTCAGATAGGGAAGCTGTGCTTATTA
CTTTGAATAGACCAATTGTTTATGCACAGCCTGTGGCCTTTGATAGAGCTGTGCTGTTTTGGCTGAATTATAAGGCCGCCTATGACAACT
GGAATGAACAACGAATGGCTTTACATAAGGATATTCATATGGCTACAAAGGAAGTAGTAGATATGCTACCTGGTATCCAGCAAACATCAG
CCCAGGCCTTTGGGACTCTTTTTCTCCAGCTCACTGTCAATGATCTGGGAATTTGCCTACCTATCACAAATACTGCACAGTCTAATCATA
CTGGAGACCTTGACACTGGTTCTGCTTTGGTATTAACCATTGAAAGTACTCTCATCACTGCATGCTCTTCAGAGTCTCTGGTTAGCAAAG
GGCATTTCAAAAACTTTTGTATCCGTTTTGCTGATGGATTTGAGACATCATGGGATGACTGGAAACCAGAAATTCATGGGGATTTAGTGA
TGAATGCCTGTGTAGTTCCAGATGGCACCTATGAAGTATGTTCAAGAACTACAGGACAAGCAGCAGCTGAAAGCAGTAGTGCTGGAACCT
GGACACTCAACGTATTGTGGAAAATGTGTGGGATTGATGTTCACATGGATCCTAACATTGGCAAAAGGCTTAATGCTCTGGGCAATACTC
TTACAACACTGACAGGAGAGGAAGACATAGATGACATTGCTGACTTAAATTCAGTGAACATAGCTGACCTGTCAGATGAGGATGAAGTTG
ATACTATGTCTCCCACTATCCATACTGAAGCCACAGATTATCGAAGACAGGCAGCATCTGCTAGCCAGCCGGGAGAACTTAGAGGAAGAA
AAATTATGAAGCGTATAGTGGATATCAGAGAACTGAATGAACAGGCCAAAGTAATAGATGATCTGAAAAAATTAGGTGCAAGTGAAGGAA
CCATAAACCAGGAAATTCAACGTTACCAACAGTTAGAATCTGTGGCTGTGAATGACATTAGAAGAGATGTTCGTAAAAAATTACGGAGGT
CCAGTATGCGGGCTGCTTCCCTAAAGGATAAGTGGGGTTTGAGTTACAAACCAAGTTACAGCCGATCAAAAAGCATTTCTGCTTCTGGAA
GACCACCTCTTAAGCGAATGGAAAGGGCAAGTTCTCGAGTAGGAGAAACTGAAGAGCTCCCAGAAATCCGTGTGGATGCAGCATCTCCTG
GACCTAGAGTAACTTTTAATATCCAGGATACAATAGCAGAAATTAGAAGGAAGAAGATCAGCTTCAAAGTTGTATTCTAA

>10454_10454_6_BTBD2-KIAA1109_BTBD2_chr19_1990003_ENST00000255608_KIAA1109_chr4_123107191_ENST00000455637_length(amino acids)=3891AA_BP=329
MAAGGSGGRASCPPGVGVGPGTGGSPGPSANAAATPAPGNAAAAAAAAAAAAAAPGPTPPAPPGPGTDAQAAGAERAEEAAGPGAAALQR
EAAYNWQASKPTVQERFAFLFNNEVLCDVHFLVGKGLSSQRIPAHRFVLAVGSAVFDAMFNGGMATTSTEIELPDVEPAAFLALLKFLYS
DEVQIGPETVMTTLYTAKKYAVPALEAHCVEFLKKNLRADNAFMLLTQARLFDEPQLASLCLENIDKNTADAITAEGFTDIDLDTLVAVL
ERDTLGIREVRLFNAVVRWSEAECQRQQLQVTPENRRKVLGKALGLIRFPLMTIEEFAADPKAETRLYITVNDFEFHVYNRSDLYGRLQE
LFGLEPTIIPPKKDDDKTREIGRTRTQSKIERVKVKTESQDPTSSWRSLIPVIKVNVSTGRLAFGNHYQPQTLCINFDDAFLTYTTKPPS
SHLDQFMHIVKGKLENVRVMLVPSPRYVGLQNDEPPRLMGEGFVVMQSNDVDIYYYMDEPGLVPEETEENIEGEMSSEDCKLQDLPPCWG
LDIVCGKGTDFNYGPWADRQRDCLWKFFFPPDYQVLKVSEIAQPGRPRQILAFELRMNIIADATIDLLFTKNRETNAVHVNVGAGSYLEI
NIPMTVEENGYTPAIKGQLLHVDATTSMQYRTLLEAEMLAFHINASYPRIWNMPQTWQCELEVYKATYHFIFAQKNFFTDLIQDWSSDSP
PDIFSFVPYTWNFKIMFHQFEMIWAANQHNWIDCSTKQQENVYLAACGETLNIDFSLPFTDFVPATCNTKFSLRGEDVDLHLFLPDCHPS
KYSLFMLVKNCHPNKMIHDTGIPAECQSGQKTVKPKWRNVTQEKSGWVECWTVPSVMLTIDYTWHPIYPQKADEQLKQSLSEMEETMLSV
LRPSQKTSDRVVSSPSTSSRPPIDPSELPPDKLHVEMELSPDSQITLYGPLLNAFLCIKENYFGEDDMYMDFEEVISSPVLSLSTSSSSG
WTAVGMENDKKENEGSAKSIHPLALRPWDITVLVNLYKVHGRLPVHGTTDGPECPTAFLERLCFEMKKGFRETMLQLILSPLNVFVSDNY
QQRPPVDEVLREGHINLSGLQLRAHAMFSAEGLPLGSDSLEYAWLIDVQAGSLTAKVTAPQLACLLEWGQTFVFHVVCREYELERPKSVI
ICQHGIDRRFCESKLSCIPGPCPTSDDLKYTMIRLAVDGADIYIVEHGCATNIKMGAIRVANCNLHNQSVGEGISAAIQDFQVRQYIEQL
NNCRIGLQPAVLRRAYWLEAGSANLGLITVDIALAADHHSKHEAQRHFLETHDARTKRLWFLWPDDILKNKRCRNKCGCLGGCRFFGGTV
TGLDFFKLEELTPSSSSAFSSTSAESDMYYGQSLLQPGEWIITKEIPKIIDGNVNGMKRKEWENKSVGIEVERKTQHLSLQVPLRSHSSS
SSSEENSSSSAAQPLLAGEKESPSSVADDHLVQKEFLHGTKRDDGQASIPTEISGNSPVSPNTQDKSVGQSPLRSPLKRQASVCSTRLGS
TKSLTAAFYGDKQPVTVGVQFSSDVSRSDENVLDSPKQRRSFGSFPYTPSADSNSFHQYRSMDSSMSMADSEAYFSAAEEFEPISSDEGP
GTYPGRKKKKKQTQQIDYSRGSIYHSVEGPLTGHGESIQDSRTLPFKTHPSQASFVSALGGEDDVIEHLYIVEGEKTVESEQITPQQPVM
NCYQTYLTQFQVINWSVKHPTNKRTSKSSLHRPLDLDTPTSEESSSSFEQLSVPTFKVIKQGLTANSLLDRGMQLSGSTSNTPYTPLEKK
LADNTDDETLTEEWTLDQPVSQTRTTAIVEVKGTVDIVLTPLVAEALDRYIEAMVHCASTRHPAAIVDDLHAKVLREAVQNSKTTFSENL
SSKQDIRGTKTEQSTIGTTNQGQAQTNLTMKQDNVTIKGLQTNVSIPKVNLCLLQASVEESPTTAPSRSVTHVSLVALCFDRIATQVRMN
RGVVEETSNNAEPGRTSNFDRYVHATKMQPQSSGSLRSNAGAEKGKEIAAKLNIHRVHGQLRGLDTTDIGTCAITAIPFEKSKVLFTLEE
LDEFTFVDETDQQAVPDVTRIGPSQEKWGWIMFECGLENLTIKGGRQSGAVLYNSFGIMGKASDTERGGVLTSNNSSDSPTGSGYNTDVS
DDNLPCDRTSPSSDLNGNSVSDEQDEGVESDDLKKDLPLMPPPPDSCSMKLTIKEIWFSFAAPTNVRSHTHAFSRQLNLLSTATPAVGAW
LVPIDQLKSSLNKLETEGTLRICAVMGCIMTEALENKSVHFPLRSKYNRLTKVARFLQENPSCLLCNILHHYLHQANYSIIDDATMSDGL
PALVTLKKGLVALARQWMKFIVVTPAFKGVSLHRPAQPLKPQIAMDHEHEDGLGLDNGGGLQSDTSADGAEFEFDAATVSEHTMLLEGTA
NRPPPGSSGPVTGAEIMRKLSKTHTHSDSALKIKGIHPYHSLSYTSGDTATDSPVHVGRAGMPVKDSPRKESLLSYLTGSFPSLHNLLEG
TPQRSSAAVKSSSLTRTGNTVATDMLSEHPLLSEPSSVSFYNWMSNAVGNRGSVLQESPVTKSGHNSLPTGVAPNLPTIPSASDFNTVLS
SDQNTLDGTHSQHSTSQDDVAGVEEANQGFPAVQLADAQVVFKPLLSHTGIQSQDTMPFCYRMYFGEHLSFSGTLDCLRADIVDSDTAKE
RKGKRARRQGHVNLPPLEFKPALMLGTFSISAVVMEKSVCTPQNSTSALSFHDLSKRYYNTFHCNFTISCQSISQHVDMALVRLIHQFST
MIDDIKATQTDIKLSRYTAGSASPTPTFKTRKHRDFRSSDFSRSSRGSLNGGNRVNNAKNKRTNNENNKKESRNKNSLGRSERRTSKVSR
KGSKDVVDHMTIHMDDSDSITVSEQSEPSAECWQNMYKLLNFYSLISDPTGILEKSSETFGPAGVRSPTEPTCKVVFENEQDNSSLTKTQ
RKRSLVTSEPQHVTLIVFGIGMVNRTHLEADIGGLTMESELKRIHGSFTLKEKMKDVLHQKMTETCATAHIGGVNIVLLEGITPNIQLED
FPTSPTSTAKQEFLTVVKCSIAKSQALYSAQRGLKTNNAAVFKVGAISINIPQHPATLHSMMVRSSHQLSKQISDLIRQPSTAPQPVKED
IATPLPSEKTPTSVNQTPVETNEFPQLPEGLEKKPIVLKFSAMLDGIAIGAALLPSLKAEYKMGRMRSHGMTGAQTRFTFELPNHRLRFT
SKVSATDMSTIPPSASLNLPPVTMSGKYIMEEHDSYSDQVWSIDELPSKQGYYLQGNYLRCVAEVGSFEHNLTTDLLNHLVFVQKVFMKE
VNEVIQKVSGGEQPIPLWNEHDGTADGDKPKILLYSLNLQFKGIQVTATTPSMRAVRFETGLIELELSNRLQTKASPGSSSYLKLFGKCQ
VDLNLALGQIVKHQVYEEAGSDFHQVAYFKTRIGLRNALREEISGSSDREAVLITLNRPIVYAQPVAFDRAVLFWLNYKAAYDNWNEQRM
ALHKDIHMATKEVVDMLPGIQQTSAQAFGTLFLQLTVNDLGICLPITNTAQSNHTGDLDTGSALVLTIESTLITACSSESLVSKGHFKNF
CIRFADGFETSWDDWKPEIHGDLVMNACVVPDGTYEVCSRTTGQAAAESSSAGTWTLNVLWKMCGIDVHMDPNIGKRLNALGNTLTTLTG
EEDIDDIADLNSVNIADLSDEDEVDTMSPTIHTEATDYRRQAASASQPGELRGRKIMKRIVDIRELNEQAKVIDDLKKLGASEGTINQEI
QRYQQLESVAVNDIRRDVRKKLRRSSMRAASLKDKWGLSYKPSYSRSKSISASGRPPLKRMERASSRVGETEELPEIRVDAASPGPRVTF
NIQDTIAEIRRKKISFKVVFX

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Fusion Gene PPI Analysis for BTBD2-KIAA1109


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for BTBD2-KIAA1109


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for BTBD2-KIAA1109


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneC4693347ALKURAYA-KUCINSKAS SYNDROME4GENOMICS_ENGLAND;UNIPROT
TgeneC0036572Seizures1GENOMICS_ENGLAND