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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:DENND4C-RHOBTB2 (FusionGDB2 ID:HG55667TG23221)

Fusion Gene Summary for DENND4C-RHOBTB2

check button Fusion gene summary
Fusion gene informationFusion gene name: DENND4C-RHOBTB2
Fusion gene ID: hg55667tg23221
HgeneTgene
Gene symbol

DENND4C

RHOBTB2

Gene ID

55667

23221

Gene nameDENN domain containing 4CRho related BTB domain containing 2
SynonymsC9orf55|C9orf55B|RAB10GEF|bA513M16.3DBC2|EIEE64|p83
Cytomap('DENND4C')('RHOBTB2')

9p22.1

8p21.3

Type of geneprotein-codingprotein-coding
DescriptionDENN domain-containing protein 4CDENN/MADD domain containing 4A pseudogeneDENN/MADD domain containing 4Crho-related BTB domain-containing protein 2deleted in breast cancer 2 gene protein
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000380432, ENST00000434457, 
ENST00000602925, 
Fusion gene scores* DoF score9 X 9 X 6=4863 X 4 X 2=24
# samples 124
** MAII scorelog2(12/486*10)=-2.01792190799726
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(4/24*10)=0.736965594166206
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: DENND4C [Title/Abstract] AND RHOBTB2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointDENND4C(19357152)-RHOBTB2(22861938), # samples:2
DENND4C(19357152)-RHOBTB2(22861937), # samples:2
Anticipated loss of major functional domain due to fusion event.DENND4C-RHOBTB2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
DENND4C-RHOBTB2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across DENND4C (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across RHOBTB2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4PRADTCGA-EJ-7785-01ADENND4Cchr9

19357152

-RHOBTB2chr8

22861938

+
ChimerDB4PRADTCGA-EJ-7785-01ADENND4Cchr9

19357152

+RHOBTB2chr8

22861938

+
ChimerDB4PRADTCGA-EJ-7785DENND4Cchr9

19357152

+RHOBTB2chr8

22861937

+


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Fusion Gene ORF analysis for DENND4C-RHOBTB2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000380432ENST00000523918DENND4Cchr9

19357152

+RHOBTB2chr8

22861938

+
5CDS-3UTRENST00000380432ENST00000523918DENND4Cchr9

19357152

+RHOBTB2chr8

22861937

+
5CDS-3UTRENST00000434457ENST00000523918DENND4Cchr9

19357152

+RHOBTB2chr8

22861938

+
5CDS-3UTRENST00000434457ENST00000523918DENND4Cchr9

19357152

+RHOBTB2chr8

22861937

+
5CDS-3UTRENST00000602925ENST00000523918DENND4Cchr9

19357152

+RHOBTB2chr8

22861938

+
5CDS-3UTRENST00000602925ENST00000523918DENND4Cchr9

19357152

+RHOBTB2chr8

22861937

+
5CDS-5UTRENST00000380432ENST00000251822DENND4Cchr9

19357152

+RHOBTB2chr8

22861938

+
5CDS-5UTRENST00000380432ENST00000251822DENND4Cchr9

19357152

+RHOBTB2chr8

22861937

+
5CDS-5UTRENST00000434457ENST00000251822DENND4Cchr9

19357152

+RHOBTB2chr8

22861938

+
5CDS-5UTRENST00000434457ENST00000251822DENND4Cchr9

19357152

+RHOBTB2chr8

22861937

+
5CDS-5UTRENST00000602925ENST00000251822DENND4Cchr9

19357152

+RHOBTB2chr8

22861938

+
5CDS-5UTRENST00000602925ENST00000251822DENND4Cchr9

19357152

+RHOBTB2chr8

22861937

+
In-frameENST00000380432ENST00000519685DENND4Cchr9

19357152

+RHOBTB2chr8

22861938

+
In-frameENST00000380432ENST00000519685DENND4Cchr9

19357152

+RHOBTB2chr8

22861937

+
In-frameENST00000380432ENST00000522948DENND4Cchr9

19357152

+RHOBTB2chr8

22861938

+
In-frameENST00000380432ENST00000522948DENND4Cchr9

19357152

+RHOBTB2chr8

22861937

+
In-frameENST00000434457ENST00000519685DENND4Cchr9

19357152

+RHOBTB2chr8

22861938

+
In-frameENST00000434457ENST00000519685DENND4Cchr9

19357152

+RHOBTB2chr8

22861937

+
In-frameENST00000434457ENST00000522948DENND4Cchr9

19357152

+RHOBTB2chr8

22861938

+
In-frameENST00000434457ENST00000522948DENND4Cchr9

19357152

+RHOBTB2chr8

22861937

+
In-frameENST00000602925ENST00000519685DENND4Cchr9

19357152

+RHOBTB2chr8

22861938

+
In-frameENST00000602925ENST00000519685DENND4Cchr9

19357152

+RHOBTB2chr8

22861937

+
In-frameENST00000602925ENST00000522948DENND4Cchr9

19357152

+RHOBTB2chr8

22861938

+
In-frameENST00000602925ENST00000522948DENND4Cchr9

19357152

+RHOBTB2chr8

22861937

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000434457DENND4Cchr919357152+ENST00000519685RHOBTB2chr822861938+8546538026675732435
ENST00000434457DENND4Cchr919357152+ENST00000522948RHOBTB2chr822861938+10297538026675732435
ENST00000602925DENND4Cchr919357152+ENST00000519685RHOBTB2chr822861938+8399523326674262386
ENST00000602925DENND4Cchr919357152+ENST00000522948RHOBTB2chr822861938+10150523326674262386
ENST00000380432DENND4Cchr919357152+ENST00000519685RHOBTB2chr822861938+730841423363352100
ENST00000380432DENND4Cchr919357152+ENST00000522948RHOBTB2chr822861938+905941423363352100
ENST00000434457DENND4Cchr919357152+ENST00000519685RHOBTB2chr822861937+8546538026675732435
ENST00000434457DENND4Cchr919357152+ENST00000522948RHOBTB2chr822861937+10297538026675732435
ENST00000602925DENND4Cchr919357152+ENST00000519685RHOBTB2chr822861937+8399523326674262386
ENST00000602925DENND4Cchr919357152+ENST00000522948RHOBTB2chr822861937+10150523326674262386
ENST00000380432DENND4Cchr919357152+ENST00000519685RHOBTB2chr822861937+730841423363352100
ENST00000380432DENND4Cchr919357152+ENST00000522948RHOBTB2chr822861937+905941423363352100

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000434457ENST00000519685DENND4Cchr919357152+RHOBTB2chr822861938+0.0007862130.9992138
ENST00000434457ENST00000522948DENND4Cchr919357152+RHOBTB2chr822861938+0.0008372620.9991628
ENST00000602925ENST00000519685DENND4Cchr919357152+RHOBTB2chr822861938+0.0008552560.9991447
ENST00000602925ENST00000522948DENND4Cchr919357152+RHOBTB2chr822861938+0.0009075750.99909246
ENST00000380432ENST00000519685DENND4Cchr919357152+RHOBTB2chr822861938+0.0006599970.99934
ENST00000380432ENST00000522948DENND4Cchr919357152+RHOBTB2chr822861938+0.0007017510.9992982
ENST00000434457ENST00000519685DENND4Cchr919357152+RHOBTB2chr822861937+0.0007862130.9992138
ENST00000434457ENST00000522948DENND4Cchr919357152+RHOBTB2chr822861937+0.0008372620.9991628
ENST00000602925ENST00000519685DENND4Cchr919357152+RHOBTB2chr822861937+0.0008552560.9991447
ENST00000602925ENST00000522948DENND4Cchr919357152+RHOBTB2chr822861937+0.0009075750.99909246
ENST00000380432ENST00000519685DENND4Cchr919357152+RHOBTB2chr822861937+0.0006599970.99934
ENST00000380432ENST00000522948DENND4Cchr919357152+RHOBTB2chr822861937+0.0007017510.9992982

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Fusion Genomic Features for DENND4C-RHOBTB2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
DENND4Cchr919357152+RHOBTB2chr822861937+7.00E-080.9999999
DENND4Cchr919357152+RHOBTB2chr822861937+7.00E-080.9999999
DENND4Cchr919357152+RHOBTB2chr822861937+7.00E-080.9999999
DENND4Cchr919357152+RHOBTB2chr822861937+7.00E-080.9999999

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for DENND4C-RHOBTB2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr9:19357152/chr8:22861938)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneDENND4Cchr9:19357152chr8:22861937ENST00000380432+2228191_36413691674.0DomainuDENN
HgeneDENND4Cchr9:19357152chr8:22861937ENST00000380432+2228385_52113691674.0DomaincDENN
HgeneDENND4Cchr9:19357152chr8:22861937ENST00000380432+222840_19913691674.0DomainMABP
HgeneDENND4Cchr9:19357152chr8:22861937ENST00000380432+2228523_64113691674.0DomaindDENN
HgeneDENND4Cchr9:19357152chr8:22861938ENST00000380432+2228191_36413691674.0DomainuDENN
HgeneDENND4Cchr9:19357152chr8:22861938ENST00000380432+2228385_52113691674.0DomaincDENN
HgeneDENND4Cchr9:19357152chr8:22861938ENST00000380432+222840_19913691674.0DomainMABP
HgeneDENND4Cchr9:19357152chr8:22861938ENST00000380432+2228523_64113691674.0DomaindDENN
HgeneDENND4Cchr9:19357152chr8:22861937ENST00000380432+2228821_85513691674.0RepeatNote=PPR
HgeneDENND4Cchr9:19357152chr8:22861938ENST00000380432+2228821_85513691674.0RepeatNote=PPR
TgeneRHOBTB2chr9:19357152chr8:22861937ENST00000251822010266_4420728.0DomainBTB 1
TgeneRHOBTB2chr9:19357152chr8:22861937ENST00000251822010500_5670728.0DomainBTB 2
TgeneRHOBTB2chr9:19357152chr8:22861938ENST00000251822010266_4420728.0DomainBTB 1
TgeneRHOBTB2chr9:19357152chr8:22861938ENST00000251822010500_5670728.0DomainBTB 2
TgeneRHOBTB2chr9:19357152chr8:22861937ENST00000251822010140_1430728.0Nucleotide bindingGTP
TgeneRHOBTB2chr9:19357152chr8:22861937ENST0000025182201021_280728.0Nucleotide bindingGTP
TgeneRHOBTB2chr9:19357152chr8:22861937ENST0000025182201084_880728.0Nucleotide bindingGTP
TgeneRHOBTB2chr9:19357152chr8:22861938ENST00000251822010140_1430728.0Nucleotide bindingGTP
TgeneRHOBTB2chr9:19357152chr8:22861938ENST0000025182201021_280728.0Nucleotide bindingGTP
TgeneRHOBTB2chr9:19357152chr8:22861938ENST0000025182201084_880728.0Nucleotide bindingGTP
TgeneRHOBTB2chr9:19357152chr8:22861937ENST000002518220101_2100728.0RegionNote=Rho-like
TgeneRHOBTB2chr9:19357152chr8:22861938ENST000002518220101_2100728.0RegionNote=Rho-like

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


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Fusion Gene Sequence for DENND4C-RHOBTB2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>22263_22263_1_DENND4C-RHOBTB2_DENND4C_chr9_19357152_ENST00000380432_RHOBTB2_chr8_22861937_ENST00000519685_length(transcript)=7308nt_BP=4142nt
TCAGAATCAGATGTACCTCTTTTCTGCCTTCCTATGGGAGCTACTATTGAGTGCTGGGATCCTGAAACCAAATATCCACTTCCAGTTTTT
TCAACTTTTGTCTTGACAGGTTCTTCAGCCAAAAAGGTATATGGAGCTGCCATTCAGTTTTATGAACCTTACTCTCGGGAACTTCTATCA
GAGAAACAGCTTATGCACCTGGGCTTGTTGACGCCTGTGGAGAGAAAAATGGTCTCCAAATCCATCAATACAAACAAATGCATTTGTTTA
CTCTCACACTGGCCTTTTTTTGAAGCTTTTAGGAAATTTCTTATGTTTATCTACAAACTTTCTGTGTCTGGACCACATCCTCTTCCCATT
GAAAAGCACATTTCACATTTTATGCAAAACATCCCTTTTCCTTCACCACAAAGACCGAGAATCCTTGTCCAGCTGTCAGTCCATGATGCA
TTAATATTATCACAGCCAGTTTCTACACCTTTACCACTAAGTGGAGCCAACTTTAGCACCTTGCTAATGAATCTGGGTCCTGAGAATTGT
GCAACACTGCTGCTCTTTGTTTTACTTGAGAGTAAAATTCTGCTGCATTCTCTTAGGCCAGCTGTCTTGACTGGGGTAGCTGAAGCTGTT
GTAGCTATGATCTTTCCATTTCAGTGGCAATGCCCATATATTCCCCTTTGTCCTCTTTCACTGGCTGCAGTGCTTAGTGCACCTTTACCA
TTTATAGTTGGAGTTGACTCAAGGTATTTTGATCTTCATGACCCACCACAAGATGTTGTTTGCATTGACTTGGATACGAACATGTTATAT
GTATCAGATGAAAAGAAGAACATGAACTGGAAGCAACTTCCCAAAAAGCCGTGCAAAAATCTACTTAGCACCTTAAAGAAATTGTATCCC
CAGCTGTCTTCAGTTCACCAAAAAACTCAAGAAGGCTCAGCGATTGACATGACTCCAATTGAAGCAGATTTCTCCTGGCAAAAGAAGATG
ACACAGCTTGAGATGGAAATTCAAGAGGCATTTTTGCGCTTTATGGCGTCTATTTTAAAAGGATATAGAACATATCTCAGACCAATCACA
GAGGCTCCTTCAAATAAAGCCACAGCTGCTGATTCATTGTTTGACCGACAGGGATTTTTAAAAAGTCGAGATCGTGCCTATGCAAAATTC
TATACCCTTTTATCCAAAACACAGATTTTTATTCGTTTCATTGAAGAATGCAGTTTTGTAAGTGATAAAGATACTGGATTAGCATTTTTT
GATGACTGCATAGAAAAGTTGTTTCCTGATAAAGGCACAGAGAAAACAGATAAGGTTGATTTTGATTCAGCAGAAGATACCAGATTGATA
GAACTAGATGATTCACAGAAAAGTGAGCATACTGTATTTATAATGCCGCCAGAGCCACCTCCTGATGATGGAAAGGACCTGTCACCAAAG
TACAGTTACAAATACTTTCCAAGACTGGACCTTAAGCTTTTTGACAGACCGCAGGAGTTGAAACTTTGTTTTAGTAGACACCCTACTGGG
AATAGCATTACAAAGAGTCCACCTCTCATGGCTAAGAGAACTAAACAGGAAATAAAAACAGCTCATAAATTGGCGAAGAGATGTTATACA
AATCCACCACAGTGGGCCAAGTGTCTGTTTAGTCATTGTTACAGTTTATGGTTTATTTGTCTTCCGGCCTATGTTAGAGTTTCTCATCCT
AAAGTCAGAGCACTTCAGCAGGCATATGATGTACTTATTAAGATGAGGAAAACAGATGTGGATCCCTTAGATGAGGTGTGCTATCGAGTA
GTGATGCAGCTTTGTGGACTTTGGGGTCATCCTGTTTTAGCAGTGAGAGTCTTATTTGAAATGAAAACTGCTAGGATAAAGCCTAATGCT
ATTACTTATGGTTATTATAATAAGGTAGTCTTGGAGAGCCCGTGGCCTAGCAGTACCCGCAGTGGTATTTTCTTATGGACGAAGGTACGG
AATGTGGTACGTGGCTTGGCACAGTTTAGGCAGCCGCTTAAAAAGACTGTGCAAAGGTCACAGGTCTCCTCAATATCAGGTGGTCAGTCT
GACCAAGGATACGGGTCTAAGGATGAACTTATAAAGGATGATGCAGAAATTCATGTGCCTGAAGAACAGGCAGCAAGAGAATTGATAACT
AAAACAAAAATGCAAACAGAAGAGGTGTGTGATGCCTCTGCTATTGTGGCAAAACATTCACAACCTAGTCCAGAGCCTCACAGTCCTACT
GAACCTCCTGCATGGGGCAGCAGTATTGTGAAAGTTCCGTCTGGTATATTTGATGTCAACAGCAGGAAAAGTAGCACTGGTAGTATATCA
AATGTGCTGTTTTCTACTCAAGATCCAGTTGAAGATGCAGTCTTTGGCGAAGCTACTAATCTCAAGAAGAATGGTGATAGAGGAGAAAAA
AGACAAAAGCATTTTCCTGAGAGGAGTTGTAGTTTTAGTTCTGAAAGTCGAGCAGGAATGTTGCTTAAGAAGAGTAGTTTGGATTCGAAT
TCAAGTGAAATGGCTATCATGATGGGAGCAGATGCCAAGATTCTCACAGCAGCATTGACATGTCCTAAGACTTCTCTACTTCATATTGCA
AGAACCCATAGCTTTGAGAATGTTAGCTGTCACCTACCTGATAGTAGGACTTGTATGTCTGAAAGCACTTGGAATCCTGAGCACAGATCA
TCTCCGGTGCCAGAGATGCTTGAGGAAAGCCAAGAACTCCTTGAGCCTGTGGTTGATGACGTACCTAAAACTACTGCAACAGTAGATACA
TATGAGAGTCTACTAAGTGATAGTAACAGTAATCAGTCCAGAGACTTGAAAACAGTATCCAAAGATCTGAGGAATAAGAGAAGTAGTTTA
TATGGTATTGCTAAGGTGGTTCAGAGGGAAGATGTTGAAACTGGACTAGATCCTTTGTCTCTTTTAGCCACTGAATGTACAGGAGGAAAA
ACTCCTGATTCTGAAGATAAGTTGTTTTCTCCAGTTATTGCACGTAATCTGGCTGATGAAATAGAAAGCTATATGAACCTAAAAAGTCCC
CTAGGTAGTAAATCTTCTAGTATGGAATTACACAGAGAGGAAAACAGAGAGTCTGGCATGACTACTGCATTTATTCATGCTCTAGAGAGG
AGATCAAGCCTACCTTTAGATCATGGTTCACCAGCACAGGAAAATCCTGAAAGTGAAAAGAGCTCACCTGCAGTGTCCAGGTCTAAAACT
TTTACTGGGCGTTTCAAGCAGCAAACCCCCTCTCGAACTCATAAAGAACGTTCAACTTCTTTGTCAGCACTGGTGCGTTCTTCGCCACAT
GGCTCGTTGGGTTCTGTAGTAAATTCTTTGTCAGGGCTAAAGCTGGATAATATACTCTCAGGGCCCAAGATAGATGTCCTGAAATCTGGT
ATGAAACAAGCAGCGACAGTAGCCAGTAAGATGTGGGTAGCTGTTGCGTCTGCCTACAGCTACTCAGATGATGAGGAAGAAACTAATAGA
GACTACAGCTTCCCAGCTGGCCTAGAAGACCATATTTTGGGGGAGAATATATCGCCTAACACAAGTATCTCAGGGTTGGTCCCCAGTGAA
CTTACCCAGAGCAACACAAGTCTTGGCAGTAGCAGCAGTAGTGGAGATGTAGGAAAACTGCATTATCCAACAGGTGAAGTTCCATTTCCA
AGAGGCATGAAAGGGCAAGACTTTGAAAAATCAGATCATGGTTCTTCTCAAAATACCAGCATGTCTAGCATCTATCAGAATTGTGCAATG
GAGGTTTTGATGTCCAGTTGTTCACAGTGTAGAGCTTGTGGAGCTTTAGTTTATGATGAAGAAATTATGGCTGGATGGACAGCAGATGAC
TCAAATTTGAATACAGCTTGTCCATTCTGTAAAAGCAACTTCTTGCCTCTTCTCAATATAGAATTCAAAGATTTGAGAGGTTCTGCAAGC
TTTTTCCTGAAACCAAGTACCTCTGGTGACAGTTTACAAAGTGGAAGCATTCCATTGGCAAATGAATCCTTGGAGCACAAACCTGTATCC
AGTTTAGCAGAACCTGACTTGATCAACTTTATGGACTTCCCAAAACATAACCAGATCATAACTGAAGAAACAGGCTCTGCAGTTGAACCA
AGGTCCCGTTTAATGGATTCTGACATGGATTATGAAAGGCCAAACGTAGAGACCATCAAGTGCGTTGTGGTGGGGGACAACGCCGTGGGT
AAGACCAGGCTCATCTGTGCCCGCGCTTGCAATGCCACCCTCACCCAGTACCAGCTGCTGGCCACGCATGTGCCCACAGTATGGGCCATC
GACCAATATCGTGTGTGCCAGGAGGTGCTGGAACGCTCCCGAGACGTGGTAGATGATGTCAGCGTCTCTCTGCGCCTCTGGGACACCTTT
GGAGACCACCACAAAGACCGTCGCTTTGCTTATGGGAGATCTGATGTGGTGGTTCTGTGCTTCTCCATTGCCAACCCCAATTCCCTCCAC
CATGTCAAGACCATGTGGTACCCAGAAATCAAGCACTTCTGCCCCCGAGCACCTGTCATCTTGGTGGGCTGCCAGTTGGACCTGCGCTAC
GCTGACCTGGAGGCTGTCAACAGGGCTAGGCGACCCTTGGCTAGGCCCATCAAACCTAATGAAATCCTGCCCCCAGAGAAGGGTCGGGAG
GTGGCCAAGGAGCTGGGCATCCCCTACTATGAGACCAGCGTGGTGGCCCAGTTCGGCATCAAGGACGTCTTTGACAACGCCATCCGAGCT
GCACTCATCTCCCGCCGCCACCTGCAGTTCTGGAAGTCCCACCTCCGCAATGTGCAGCGGCCTCTGCTGCAGGCACCCTTCCTACCCCCC
AAGCCACCGCCCCCGATCATCGTGGTGCCCGACCCTCCCTCCAGCAGCGAGGAGTGCCCCGCCCACCTCCTGGAGGACCCGCTCTGCGCG
GACGTCATCCTGGTGCTGCAGGAGCGGGTGCGCATCTTTGCCCACAAGATCTACCTCTCCACCTCTTCCTCCAAGTTCTATGACCTGTTC
CTCATGGACCTGAGTGAGGGGGAGCTGGGGGGCCCCTCGGAGCCAGGGGGCACCCACCCAGAGGACCACCAGGGCCACTCTGATCAACAC
CACCACCATCACCACCACCACCATGGGCGAGACTTCCTGCTCCGAGCAGCCAGCTTTGACGTGTGCGAGAGCGTGGATGAGGCTGGGGGC
TCCGGTCCTGCTGGCCTCCGTGCTTCCACCAGCGACGGGATCTTACGGGGCAACGGAACAGGGTACCTACCGGGCAGGGGTCGTGTGCTG
TCTTCCTGGAGCCGAGCTTTTGTGAGCATCCAGGAAGAGATGGCAGAAGATCCTCTCACCTACAAATCCCGGCTGATGGTGGTGGTGAAG
ATGGACAGTTCCATCCAGCCGGGGCCCTTCCGGGCTGTCCTCAAGTACCTGTACACGGGGGAGCTAGATGAGAACGAGCGTGACCTCATG
CACATTGCCCACATTGCTGAGCTGCTCGAGGTCTTTGATCTGCGCATGATGGTGGCCAACATTCTCAACAATGAGGCCTTCATGAACCAG
GAGATCACCAAGGCCTTCCACGTCCGCCGGACCAACCGGGTTAAGGAGTGCTTGGCAAAAGGCACCTTCTCAGATGTGACCTTCATCCTG
GATGATGGCACCATCAGCGCCCACAAGCCCCTGTTGATTTCCAGCTGTGACTGGATGGCTGCCATGTTTGGGGGGCCATTTGTGGAGAGC
TCCACCCGGGAGGTGGTGTTTCCCTACACAAGCAAGAGCTGCATGCGGGCCGTGCTGGAATACCTCTACACCGGCATGTTCACCTCCAGC
CCCGACCTGGATGACATGAAGCTCATCATTCTAGCCAACCGCCTCTGCCTGCCACACCTGGTTGCCCTCACAGAGCAGTACACAGTGACC
GGGCTGATGGAAGCGACCCAGATGATGGTGGACATCGATGGGGACGTCCTTGTGTTCCTGGAACTGGCTCAGTTCCACTGTGCGTACCAG
CTGGCCGACTGGTGTCTCCACCACATCTGCACCAACTACAACAACGTGTGCCGCAAGTTCCCCCGAGACATGAAGGCCATGTCCCCAGAA
AACCAGGAGTATTTCGAGAAGCATCGGTGGCCACCTGTGTGGTACCTGAAGGAGGAAGATCATTACCAGCGGGCACGGAAGGAGCGTGAG
AAGGAGGACTACCTCCACCTCAAGCGGCAGCCCAAACGGCGTTGGCTCTTCTGGAACAGTCCATCCTCCCCGTCTTCCTCGGCAGCCTCC
TCCTCATCCCCATCTTCCTCCTCGGCTGTGGTCTGAGATGCTGCCACCCTCTTCTGACCCTGCTGCTGTTGTCCCCATCCGCCTTCACCC
CTCTGCTCTTCCGCATCACCCCATCCACCTTACAGGGACCAGGGGGCCCACGTAACCAGGACCCAGAGGGTGGAGCTCTTCTTACCAGCC
ACCGTGGCTCAGCCAGAGAGGAGCTGAGCCCTGTGGAGCAGAACGGGAACCACCTGCAGAGGTCCCCAGACCCAAAGCAGGACGGGAGAC
AACTGCTTGGAGGAGCGAAGAGCCCTGGCATTTTATCTCTGGGTTTGAGAGCCCTAGAGTCAAAGGGAAAGCCTCCCAGCCTCCAGGGCT
TCTCTGTGTGTCTTGGTTGCTGCTCTGGCCAGGGAGGCAGCCCCACTCCCAGCAAGCAGAAGTGATCCTCGAGGGTCCTGCCCCTGTTGG
CCATATCTTTCCACCGACGGACTTGAGTGTTGCATTTGTTTTGTGGGCATTTCCACACGAAGCCTACTCACACCCTCACTGGAGAAGTCA
GGGTAGAAATTGAGCCTTCAGAGCCCAACTCAAGGCTTCTACATCCTGGGGTGCAGCTGCAAAAGGCCAGACGTGGAAAGGCCTGTATCC
TGCCAGTGTCCCTCCGTCCCAGGGGGCTGTGCTAGCACAGACCTGAGAATGGGGACACAGGTCATTCAGAGCTCCAGGCCTGGAAGCAGT
GCCTCTTGGTGCAACAAGAAACTTCTCCCTCACCCCCTCCTTTACCCTCAGATTTGGAGATGGTAACCAAAGGAAGCAGCTGGGACAGGT
GGAGAAGGAAGTAGGAATGAGTGCACGGCGACCCCGTGCTCCTCAGGGCCCTCCCCTGCCTCTGGGTGGCACTGCTTTTTATAGGGTGGG
GCAAAATTAGCAAAAAACAAAAACCAATGACAACCAAACTGAAACCGAAACGAAAAATCAACAAACACTCTGTCCTCTATCCCTCCAAAG

>22263_22263_1_DENND4C-RHOBTB2_DENND4C_chr9_19357152_ENST00000380432_RHOBTB2_chr8_22861937_ENST00000519685_length(amino acids)=2100AA_BP=1362
MGATIECWDPETKYPLPVFSTFVLTGSSAKKVYGAAIQFYEPYSRELLSEKQLMHLGLLTPVERKMVSKSINTNKCICLLSHWPFFEAFR
KFLMFIYKLSVSGPHPLPIEKHISHFMQNIPFPSPQRPRILVQLSVHDALILSQPVSTPLPLSGANFSTLLMNLGPENCATLLLFVLLES
KILLHSLRPAVLTGVAEAVVAMIFPFQWQCPYIPLCPLSLAAVLSAPLPFIVGVDSRYFDLHDPPQDVVCIDLDTNMLYVSDEKKNMNWK
QLPKKPCKNLLSTLKKLYPQLSSVHQKTQEGSAIDMTPIEADFSWQKKMTQLEMEIQEAFLRFMASILKGYRTYLRPITEAPSNKATAAD
SLFDRQGFLKSRDRAYAKFYTLLSKTQIFIRFIEECSFVSDKDTGLAFFDDCIEKLFPDKGTEKTDKVDFDSAEDTRLIELDDSQKSEHT
VFIMPPEPPPDDGKDLSPKYSYKYFPRLDLKLFDRPQELKLCFSRHPTGNSITKSPPLMAKRTKQEIKTAHKLAKRCYTNPPQWAKCLFS
HCYSLWFICLPAYVRVSHPKVRALQQAYDVLIKMRKTDVDPLDEVCYRVVMQLCGLWGHPVLAVRVLFEMKTARIKPNAITYGYYNKVVL
ESPWPSSTRSGIFLWTKVRNVVRGLAQFRQPLKKTVQRSQVSSISGGQSDQGYGSKDELIKDDAEIHVPEEQAARELITKTKMQTEEVCD
ASAIVAKHSQPSPEPHSPTEPPAWGSSIVKVPSGIFDVNSRKSSTGSISNVLFSTQDPVEDAVFGEATNLKKNGDRGEKRQKHFPERSCS
FSSESRAGMLLKKSSLDSNSSEMAIMMGADAKILTAALTCPKTSLLHIARTHSFENVSCHLPDSRTCMSESTWNPEHRSSPVPEMLEESQ
ELLEPVVDDVPKTTATVDTYESLLSDSNSNQSRDLKTVSKDLRNKRSSLYGIAKVVQREDVETGLDPLSLLATECTGGKTPDSEDKLFSP
VIARNLADEIESYMNLKSPLGSKSSSMELHREENRESGMTTAFIHALERRSSLPLDHGSPAQENPESEKSSPAVSRSKTFTGRFKQQTPS
RTHKERSTSLSALVRSSPHGSLGSVVNSLSGLKLDNILSGPKIDVLKSGMKQAATVASKMWVAVASAYSYSDDEEETNRDYSFPAGLEDH
ILGENISPNTSISGLVPSELTQSNTSLGSSSSSGDVGKLHYPTGEVPFPRGMKGQDFEKSDHGSSQNTSMSSIYQNCAMEVLMSSCSQCR
ACGALVYDEEIMAGWTADDSNLNTACPFCKSNFLPLLNIEFKDLRGSASFFLKPSTSGDSLQSGSIPLANESLEHKPVSSLAEPDLINFM
DFPKHNQIITEETGSAVEPRSRLMDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLE
RSRDVVDDVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARR
PLARPIKPNEILPPEKGREVAKELGIPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQAPFLPPKPPPPIIVVPD
PPSSSEECPAHLLEDPLCADVILVLQERVRIFAHKIYLSTSSSKFYDLFLMDLSEGELGGPSEPGGTHPEDHQGHSDQHHHHHHHHHGRD
FLLRAASFDVCESVDEAGGSGPAGLRASTSDGILRGNGTGYLPGRGRVLSSWSRAFVSIQEEMAEDPLTYKSRLMVVVKMDSSIQPGPFR
AVLKYLYTGELDENERDLMHIAHIAELLEVFDLRMMVANILNNEAFMNQEITKAFHVRRTNRVKECLAKGTFSDVTFILDDGTISAHKPL
LISSCDWMAAMFGGPFVESSTREVVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIILANRLCLPHLVALTEQYTVTGLMEATQMMVD
IDGDVLVFLELAQFHCAYQLADWCLHHICTNYNNVCRKFPRDMKAMSPENQEYFEKHRWPPVWYLKEEDHYQRARKEREKEDYLHLKRQP

--------------------------------------------------------------
>22263_22263_2_DENND4C-RHOBTB2_DENND4C_chr9_19357152_ENST00000380432_RHOBTB2_chr8_22861937_ENST00000522948_length(transcript)=9059nt_BP=4142nt
TCAGAATCAGATGTACCTCTTTTCTGCCTTCCTATGGGAGCTACTATTGAGTGCTGGGATCCTGAAACCAAATATCCACTTCCAGTTTTT
TCAACTTTTGTCTTGACAGGTTCTTCAGCCAAAAAGGTATATGGAGCTGCCATTCAGTTTTATGAACCTTACTCTCGGGAACTTCTATCA
GAGAAACAGCTTATGCACCTGGGCTTGTTGACGCCTGTGGAGAGAAAAATGGTCTCCAAATCCATCAATACAAACAAATGCATTTGTTTA
CTCTCACACTGGCCTTTTTTTGAAGCTTTTAGGAAATTTCTTATGTTTATCTACAAACTTTCTGTGTCTGGACCACATCCTCTTCCCATT
GAAAAGCACATTTCACATTTTATGCAAAACATCCCTTTTCCTTCACCACAAAGACCGAGAATCCTTGTCCAGCTGTCAGTCCATGATGCA
TTAATATTATCACAGCCAGTTTCTACACCTTTACCACTAAGTGGAGCCAACTTTAGCACCTTGCTAATGAATCTGGGTCCTGAGAATTGT
GCAACACTGCTGCTCTTTGTTTTACTTGAGAGTAAAATTCTGCTGCATTCTCTTAGGCCAGCTGTCTTGACTGGGGTAGCTGAAGCTGTT
GTAGCTATGATCTTTCCATTTCAGTGGCAATGCCCATATATTCCCCTTTGTCCTCTTTCACTGGCTGCAGTGCTTAGTGCACCTTTACCA
TTTATAGTTGGAGTTGACTCAAGGTATTTTGATCTTCATGACCCACCACAAGATGTTGTTTGCATTGACTTGGATACGAACATGTTATAT
GTATCAGATGAAAAGAAGAACATGAACTGGAAGCAACTTCCCAAAAAGCCGTGCAAAAATCTACTTAGCACCTTAAAGAAATTGTATCCC
CAGCTGTCTTCAGTTCACCAAAAAACTCAAGAAGGCTCAGCGATTGACATGACTCCAATTGAAGCAGATTTCTCCTGGCAAAAGAAGATG
ACACAGCTTGAGATGGAAATTCAAGAGGCATTTTTGCGCTTTATGGCGTCTATTTTAAAAGGATATAGAACATATCTCAGACCAATCACA
GAGGCTCCTTCAAATAAAGCCACAGCTGCTGATTCATTGTTTGACCGACAGGGATTTTTAAAAAGTCGAGATCGTGCCTATGCAAAATTC
TATACCCTTTTATCCAAAACACAGATTTTTATTCGTTTCATTGAAGAATGCAGTTTTGTAAGTGATAAAGATACTGGATTAGCATTTTTT
GATGACTGCATAGAAAAGTTGTTTCCTGATAAAGGCACAGAGAAAACAGATAAGGTTGATTTTGATTCAGCAGAAGATACCAGATTGATA
GAACTAGATGATTCACAGAAAAGTGAGCATACTGTATTTATAATGCCGCCAGAGCCACCTCCTGATGATGGAAAGGACCTGTCACCAAAG
TACAGTTACAAATACTTTCCAAGACTGGACCTTAAGCTTTTTGACAGACCGCAGGAGTTGAAACTTTGTTTTAGTAGACACCCTACTGGG
AATAGCATTACAAAGAGTCCACCTCTCATGGCTAAGAGAACTAAACAGGAAATAAAAACAGCTCATAAATTGGCGAAGAGATGTTATACA
AATCCACCACAGTGGGCCAAGTGTCTGTTTAGTCATTGTTACAGTTTATGGTTTATTTGTCTTCCGGCCTATGTTAGAGTTTCTCATCCT
AAAGTCAGAGCACTTCAGCAGGCATATGATGTACTTATTAAGATGAGGAAAACAGATGTGGATCCCTTAGATGAGGTGTGCTATCGAGTA
GTGATGCAGCTTTGTGGACTTTGGGGTCATCCTGTTTTAGCAGTGAGAGTCTTATTTGAAATGAAAACTGCTAGGATAAAGCCTAATGCT
ATTACTTATGGTTATTATAATAAGGTAGTCTTGGAGAGCCCGTGGCCTAGCAGTACCCGCAGTGGTATTTTCTTATGGACGAAGGTACGG
AATGTGGTACGTGGCTTGGCACAGTTTAGGCAGCCGCTTAAAAAGACTGTGCAAAGGTCACAGGTCTCCTCAATATCAGGTGGTCAGTCT
GACCAAGGATACGGGTCTAAGGATGAACTTATAAAGGATGATGCAGAAATTCATGTGCCTGAAGAACAGGCAGCAAGAGAATTGATAACT
AAAACAAAAATGCAAACAGAAGAGGTGTGTGATGCCTCTGCTATTGTGGCAAAACATTCACAACCTAGTCCAGAGCCTCACAGTCCTACT
GAACCTCCTGCATGGGGCAGCAGTATTGTGAAAGTTCCGTCTGGTATATTTGATGTCAACAGCAGGAAAAGTAGCACTGGTAGTATATCA
AATGTGCTGTTTTCTACTCAAGATCCAGTTGAAGATGCAGTCTTTGGCGAAGCTACTAATCTCAAGAAGAATGGTGATAGAGGAGAAAAA
AGACAAAAGCATTTTCCTGAGAGGAGTTGTAGTTTTAGTTCTGAAAGTCGAGCAGGAATGTTGCTTAAGAAGAGTAGTTTGGATTCGAAT
TCAAGTGAAATGGCTATCATGATGGGAGCAGATGCCAAGATTCTCACAGCAGCATTGACATGTCCTAAGACTTCTCTACTTCATATTGCA
AGAACCCATAGCTTTGAGAATGTTAGCTGTCACCTACCTGATAGTAGGACTTGTATGTCTGAAAGCACTTGGAATCCTGAGCACAGATCA
TCTCCGGTGCCAGAGATGCTTGAGGAAAGCCAAGAACTCCTTGAGCCTGTGGTTGATGACGTACCTAAAACTACTGCAACAGTAGATACA
TATGAGAGTCTACTAAGTGATAGTAACAGTAATCAGTCCAGAGACTTGAAAACAGTATCCAAAGATCTGAGGAATAAGAGAAGTAGTTTA
TATGGTATTGCTAAGGTGGTTCAGAGGGAAGATGTTGAAACTGGACTAGATCCTTTGTCTCTTTTAGCCACTGAATGTACAGGAGGAAAA
ACTCCTGATTCTGAAGATAAGTTGTTTTCTCCAGTTATTGCACGTAATCTGGCTGATGAAATAGAAAGCTATATGAACCTAAAAAGTCCC
CTAGGTAGTAAATCTTCTAGTATGGAATTACACAGAGAGGAAAACAGAGAGTCTGGCATGACTACTGCATTTATTCATGCTCTAGAGAGG
AGATCAAGCCTACCTTTAGATCATGGTTCACCAGCACAGGAAAATCCTGAAAGTGAAAAGAGCTCACCTGCAGTGTCCAGGTCTAAAACT
TTTACTGGGCGTTTCAAGCAGCAAACCCCCTCTCGAACTCATAAAGAACGTTCAACTTCTTTGTCAGCACTGGTGCGTTCTTCGCCACAT
GGCTCGTTGGGTTCTGTAGTAAATTCTTTGTCAGGGCTAAAGCTGGATAATATACTCTCAGGGCCCAAGATAGATGTCCTGAAATCTGGT
ATGAAACAAGCAGCGACAGTAGCCAGTAAGATGTGGGTAGCTGTTGCGTCTGCCTACAGCTACTCAGATGATGAGGAAGAAACTAATAGA
GACTACAGCTTCCCAGCTGGCCTAGAAGACCATATTTTGGGGGAGAATATATCGCCTAACACAAGTATCTCAGGGTTGGTCCCCAGTGAA
CTTACCCAGAGCAACACAAGTCTTGGCAGTAGCAGCAGTAGTGGAGATGTAGGAAAACTGCATTATCCAACAGGTGAAGTTCCATTTCCA
AGAGGCATGAAAGGGCAAGACTTTGAAAAATCAGATCATGGTTCTTCTCAAAATACCAGCATGTCTAGCATCTATCAGAATTGTGCAATG
GAGGTTTTGATGTCCAGTTGTTCACAGTGTAGAGCTTGTGGAGCTTTAGTTTATGATGAAGAAATTATGGCTGGATGGACAGCAGATGAC
TCAAATTTGAATACAGCTTGTCCATTCTGTAAAAGCAACTTCTTGCCTCTTCTCAATATAGAATTCAAAGATTTGAGAGGTTCTGCAAGC
TTTTTCCTGAAACCAAGTACCTCTGGTGACAGTTTACAAAGTGGAAGCATTCCATTGGCAAATGAATCCTTGGAGCACAAACCTGTATCC
AGTTTAGCAGAACCTGACTTGATCAACTTTATGGACTTCCCAAAACATAACCAGATCATAACTGAAGAAACAGGCTCTGCAGTTGAACCA
AGGTCCCGTTTAATGGATTCTGACATGGATTATGAAAGGCCAAACGTAGAGACCATCAAGTGCGTTGTGGTGGGGGACAACGCCGTGGGT
AAGACCAGGCTCATCTGTGCCCGCGCTTGCAATGCCACCCTCACCCAGTACCAGCTGCTGGCCACGCATGTGCCCACAGTATGGGCCATC
GACCAATATCGTGTGTGCCAGGAGGTGCTGGAACGCTCCCGAGACGTGGTAGATGATGTCAGCGTCTCTCTGCGCCTCTGGGACACCTTT
GGAGACCACCACAAAGACCGTCGCTTTGCTTATGGGAGATCTGATGTGGTGGTTCTGTGCTTCTCCATTGCCAACCCCAATTCCCTCCAC
CATGTCAAGACCATGTGGTACCCAGAAATCAAGCACTTCTGCCCCCGAGCACCTGTCATCTTGGTGGGCTGCCAGTTGGACCTGCGCTAC
GCTGACCTGGAGGCTGTCAACAGGGCTAGGCGACCCTTGGCTAGGCCCATCAAACCTAATGAAATCCTGCCCCCAGAGAAGGGTCGGGAG
GTGGCCAAGGAGCTGGGCATCCCCTACTATGAGACCAGCGTGGTGGCCCAGTTCGGCATCAAGGACGTCTTTGACAACGCCATCCGAGCT
GCACTCATCTCCCGCCGCCACCTGCAGTTCTGGAAGTCCCACCTCCGCAATGTGCAGCGGCCTCTGCTGCAGGCACCCTTCCTACCCCCC
AAGCCACCGCCCCCGATCATCGTGGTGCCCGACCCTCCCTCCAGCAGCGAGGAGTGCCCCGCCCACCTCCTGGAGGACCCGCTCTGCGCG
GACGTCATCCTGGTGCTGCAGGAGCGGGTGCGCATCTTTGCCCACAAGATCTACCTCTCCACCTCTTCCTCCAAGTTCTATGACCTGTTC
CTCATGGACCTGAGTGAGGGGGAGCTGGGGGGCCCCTCGGAGCCAGGGGGCACCCACCCAGAGGACCACCAGGGCCACTCTGATCAACAC
CACCACCATCACCACCACCACCATGGGCGAGACTTCCTGCTCCGAGCAGCCAGCTTTGACGTGTGCGAGAGCGTGGATGAGGCTGGGGGC
TCCGGTCCTGCTGGCCTCCGTGCTTCCACCAGCGACGGGATCTTACGGGGCAACGGAACAGGGTACCTACCGGGCAGGGGTCGTGTGCTG
TCTTCCTGGAGCCGAGCTTTTGTGAGCATCCAGGAAGAGATGGCAGAAGATCCTCTCACCTACAAATCCCGGCTGATGGTGGTGGTGAAG
ATGGACAGTTCCATCCAGCCGGGGCCCTTCCGGGCTGTCCTCAAGTACCTGTACACGGGGGAGCTAGATGAGAACGAGCGTGACCTCATG
CACATTGCCCACATTGCTGAGCTGCTCGAGGTCTTTGATCTGCGCATGATGGTGGCCAACATTCTCAACAATGAGGCCTTCATGAACCAG
GAGATCACCAAGGCCTTCCACGTCCGCCGGACCAACCGGGTTAAGGAGTGCTTGGCAAAAGGCACCTTCTCAGATGTGACCTTCATCCTG
GATGATGGCACCATCAGCGCCCACAAGCCCCTGTTGATTTCCAGCTGTGACTGGATGGCTGCCATGTTTGGGGGGCCATTTGTGGAGAGC
TCCACCCGGGAGGTGGTGTTTCCCTACACAAGCAAGAGCTGCATGCGGGCCGTGCTGGAATACCTCTACACCGGCATGTTCACCTCCAGC
CCCGACCTGGATGACATGAAGCTCATCATTCTAGCCAACCGCCTCTGCCTGCCACACCTGGTTGCCCTCACAGAGCAGTACACAGTGACC
GGGCTGATGGAAGCGACCCAGATGATGGTGGACATCGATGGGGACGTCCTTGTGTTCCTGGAACTGGCTCAGTTCCACTGTGCGTACCAG
CTGGCCGACTGGTGTCTCCACCACATCTGCACCAACTACAACAACGTGTGCCGCAAGTTCCCCCGAGACATGAAGGCCATGTCCCCAGAA
AACCAGGAGTATTTCGAGAAGCATCGGTGGCCACCTGTGTGGTACCTGAAGGAGGAAGATCATTACCAGCGGGCACGGAAGGAGCGTGAG
AAGGAGGACTACCTCCACCTCAAGCGGCAGCCCAAACGGCGTTGGCTCTTCTGGAACAGTCCATCCTCCCCGTCTTCCTCGGCAGCCTCC
TCCTCATCCCCATCTTCCTCCTCGGCTGTGGTCTGAGATGCTGCCACCCTCTTCTGACCCTGCTGCTGTTGTCCCCATCCGCCTTCACCC
CTCTGCTCTTCCGCATCACCCCATCCACCTTACAGGGACCAGGGGGCCCACGTAACCAGGACCCAGAGGGTGGAGCTCTTCTTACCAGCC
ACCGTGGCTCAGCCAGAGAGGAGCTGAGCCCTGTGGAGCAGAACGGGAACCACCTGCAGAGGTCCCCAGACCCAAAGCAGGACGGGAGAC
AACTGCTTGGAGGAGCGAAGAGCCCTGGCATTTTATCTCTGGGTTTGAGAGCCCTAGAGTCAAAGGGAAAGCCTCCCAGCCTCCAGGGCT
TCTCTGTGTGTCTTGGTTGCTGCTCTGGCCAGGGAGGCAGCCCCACTCCCAGCAAGCAGAAGTGATCCTCGAGGGTCCTGCCCCTGTTGG
CCATATCTTTCCACCGACGGACTTGAGTGTTGCATTTGTTTTGTGGGCATTTCCACACGAAGCCTACTCACACCCTCACTGGAGAAGTCA
GGGTAGAAATTGAGCCTTCAGAGCCCAACTCAAGGCTTCTACATCCTGGGGTGCAGCTGCAAAAGGCCAGACGTGGAAAGGCCTGTATCC
TGCCAGTGTCCCTCCGTCCCAGGGGGCTGTGCTAGCACAGACCTGAGAATGGGGACACAGGTCATTCAGAGCTCCAGGCCTGGAAGCAGT
GCCTCTTGGTGCAACAAGAAACTTCTCCCTCACCCCCTCCTTTACCCTCAGATTTGGAGATGGTAACCAAAGGAAGCAGCTGGGACAGGT
GGAGAAGGAAGTAGGAATGAGTGCACGGCGACCCCGTGCTCCTCAGGGCCCTCCCCTGCCTCTGGGTGGCACTGCTTTTTATAGGGTGGG
GCAAAATTAGCAAAAAACAAAAACCAATGACAACCAAACTGAAACCGAAACGAAAAATCAACAAACACTCTGTCCTCTATCCCTCCAAAG
AATGAAAATCAGAAAAAGCCCCTGCCTAGCTCACATTTCTATAAACAGAGGCCCCCATGATGAGGAGGTGAAGATTTAGGTTGCAGAATC
GACTCCAATGCCTTTCAGGAAAGGACTCGGCACTTCTCTGACTGCGGAGGCCCTGACCCTGCCAGCTGGCTCCGAGGGCAACACAGGGGC
CTGGCCTCTAGAGGGCTGGTGATTGAGGGGCCCGGGCTGGCGGCAAAGAGGGGTTTGGTCTCGGGGCTTAAATGGCACCAGACTCTTGCT
TTTGCCCATCTGGAGACTGCAGGCTCCCTTCCTTACCCTCAGAGAGTGCTTATGGTGGGTGTTTTTGCGGGGCTGCAATAGGGGCCAAAA
GTCAGGGAAAGGGGCACTGACCTGTAGTGAAAGGCCACAGGACACAGCCTTATTACTGCTGGGGTGGGATAAGGGGAAGGAGAAGAGGGA
GAATGGAGCAGGAGGAAAAGCAGAGTTGGTCTAGAGAGGAGGAGGGCGGGGCTGGAGGAATGTGGGGGATTGAAACTAGCTCCCAGCCCC
CATGGGGCAGCAGCTGGGCCACAATTGCCCCTTTCCGTTTTCTAACCCCGACTCAGATTTCACCACCCACACTCTTTTTAGGTGTAAAAG
ATGGAGTCCCACGGAGGAGGGGCAGAGCCAGGAGGCAGTGGGGCTGTGGGCTCAGAGCTCAGGAGTCGCCTTACCTGAGAGAGATGTTCT
AGCTGAGAGGGCCTGGCCCTGGGGTGGGCTCCAGGAAAACGCTGGTTAGGCCTGGGATTGAGCTAACCTGAAACAAAGGTAGCAGGCAGG
ACCTAATGACCAGAGGTTAAATCCTCATCAAGAGAGACCAGGCGGCTGGAGGACAAGCGGCTCTAACCCTGGGGGCGGCCATGTTGTCCA
GGCCCAGGCCCCTCCAGGACTGTGGCTGCCTCCCCTCCACGGCCTCCAGGGCGGCTGGCTGGAAAGCCACGCGTATGCTGCCCTCTACAG
GCTGCTCGGCCTCCCTGCAGCTCAGCGCAGCCCAGGGCTCCAAGTGAGGCCCAGAAGCCCATGGGCAGGGCTGGGGGGACGAAGGGGGAA
CCCGGAGCACCTCCACTTCTAGGGAAGATGGACAGCGTGGGGGCACACCTGGGCCTCCCGGAAGCTGTGGACGAAAGGGAGAGCGGGTCC
TCCAGGGCAAGGGGAACGGGAAATAGGTCTCCTAGGTGCCTGAAGCGCTGAGCAACCTGGGTACCCTGGTGGGGATGCAGGGAAGGCCGG
GGCAGAGAAAGTGAAGGTCGACCCAGGGCTGTAGGAAGCCATAGGAGAGTGACCACGGGATTCCCTGAGAAACAGGGCCGGCCCCCCAAC
TTCAGGGACCCACCGCCCATTCCCCGAGAGCTGTCGGAACCAGATGCAACCCGGCAGCCCAGAGAACTCTCCTGGGAGGCTGTGGGTGAG
CCAGGCCAACATTGGTGTCCCTGTCCCCAGAGGGAGGAGCAGGCAGGAGAGAGAGGGGAAGGAGGTATGAATCCCAGTCCCCAGGAACCT
AGCTCTTTAAACTCTGGGGAGTCGGATTCAGGAAACACCCCCAGGAGGCCAAGCCTGAAAACAGAGGGGAGGGAGGAAGGAAGGAGTCCC
AGCAGGAGCACAGCCCTGGTTTCCTGTCACTCAGAGCTGATTCACAGGAGGAGGGGAGGTTGGGGGGCGGGAGACAAAAACCACACCTCT

>22263_22263_2_DENND4C-RHOBTB2_DENND4C_chr9_19357152_ENST00000380432_RHOBTB2_chr8_22861937_ENST00000522948_length(amino acids)=2100AA_BP=1362
MGATIECWDPETKYPLPVFSTFVLTGSSAKKVYGAAIQFYEPYSRELLSEKQLMHLGLLTPVERKMVSKSINTNKCICLLSHWPFFEAFR
KFLMFIYKLSVSGPHPLPIEKHISHFMQNIPFPSPQRPRILVQLSVHDALILSQPVSTPLPLSGANFSTLLMNLGPENCATLLLFVLLES
KILLHSLRPAVLTGVAEAVVAMIFPFQWQCPYIPLCPLSLAAVLSAPLPFIVGVDSRYFDLHDPPQDVVCIDLDTNMLYVSDEKKNMNWK
QLPKKPCKNLLSTLKKLYPQLSSVHQKTQEGSAIDMTPIEADFSWQKKMTQLEMEIQEAFLRFMASILKGYRTYLRPITEAPSNKATAAD
SLFDRQGFLKSRDRAYAKFYTLLSKTQIFIRFIEECSFVSDKDTGLAFFDDCIEKLFPDKGTEKTDKVDFDSAEDTRLIELDDSQKSEHT
VFIMPPEPPPDDGKDLSPKYSYKYFPRLDLKLFDRPQELKLCFSRHPTGNSITKSPPLMAKRTKQEIKTAHKLAKRCYTNPPQWAKCLFS
HCYSLWFICLPAYVRVSHPKVRALQQAYDVLIKMRKTDVDPLDEVCYRVVMQLCGLWGHPVLAVRVLFEMKTARIKPNAITYGYYNKVVL
ESPWPSSTRSGIFLWTKVRNVVRGLAQFRQPLKKTVQRSQVSSISGGQSDQGYGSKDELIKDDAEIHVPEEQAARELITKTKMQTEEVCD
ASAIVAKHSQPSPEPHSPTEPPAWGSSIVKVPSGIFDVNSRKSSTGSISNVLFSTQDPVEDAVFGEATNLKKNGDRGEKRQKHFPERSCS
FSSESRAGMLLKKSSLDSNSSEMAIMMGADAKILTAALTCPKTSLLHIARTHSFENVSCHLPDSRTCMSESTWNPEHRSSPVPEMLEESQ
ELLEPVVDDVPKTTATVDTYESLLSDSNSNQSRDLKTVSKDLRNKRSSLYGIAKVVQREDVETGLDPLSLLATECTGGKTPDSEDKLFSP
VIARNLADEIESYMNLKSPLGSKSSSMELHREENRESGMTTAFIHALERRSSLPLDHGSPAQENPESEKSSPAVSRSKTFTGRFKQQTPS
RTHKERSTSLSALVRSSPHGSLGSVVNSLSGLKLDNILSGPKIDVLKSGMKQAATVASKMWVAVASAYSYSDDEEETNRDYSFPAGLEDH
ILGENISPNTSISGLVPSELTQSNTSLGSSSSSGDVGKLHYPTGEVPFPRGMKGQDFEKSDHGSSQNTSMSSIYQNCAMEVLMSSCSQCR
ACGALVYDEEIMAGWTADDSNLNTACPFCKSNFLPLLNIEFKDLRGSASFFLKPSTSGDSLQSGSIPLANESLEHKPVSSLAEPDLINFM
DFPKHNQIITEETGSAVEPRSRLMDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLE
RSRDVVDDVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARR
PLARPIKPNEILPPEKGREVAKELGIPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQAPFLPPKPPPPIIVVPD
PPSSSEECPAHLLEDPLCADVILVLQERVRIFAHKIYLSTSSSKFYDLFLMDLSEGELGGPSEPGGTHPEDHQGHSDQHHHHHHHHHGRD
FLLRAASFDVCESVDEAGGSGPAGLRASTSDGILRGNGTGYLPGRGRVLSSWSRAFVSIQEEMAEDPLTYKSRLMVVVKMDSSIQPGPFR
AVLKYLYTGELDENERDLMHIAHIAELLEVFDLRMMVANILNNEAFMNQEITKAFHVRRTNRVKECLAKGTFSDVTFILDDGTISAHKPL
LISSCDWMAAMFGGPFVESSTREVVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIILANRLCLPHLVALTEQYTVTGLMEATQMMVD
IDGDVLVFLELAQFHCAYQLADWCLHHICTNYNNVCRKFPRDMKAMSPENQEYFEKHRWPPVWYLKEEDHYQRARKEREKEDYLHLKRQP

--------------------------------------------------------------
>22263_22263_3_DENND4C-RHOBTB2_DENND4C_chr9_19357152_ENST00000380432_RHOBTB2_chr8_22861938_ENST00000519685_length(transcript)=7308nt_BP=4142nt
TCAGAATCAGATGTACCTCTTTTCTGCCTTCCTATGGGAGCTACTATTGAGTGCTGGGATCCTGAAACCAAATATCCACTTCCAGTTTTT
TCAACTTTTGTCTTGACAGGTTCTTCAGCCAAAAAGGTATATGGAGCTGCCATTCAGTTTTATGAACCTTACTCTCGGGAACTTCTATCA
GAGAAACAGCTTATGCACCTGGGCTTGTTGACGCCTGTGGAGAGAAAAATGGTCTCCAAATCCATCAATACAAACAAATGCATTTGTTTA
CTCTCACACTGGCCTTTTTTTGAAGCTTTTAGGAAATTTCTTATGTTTATCTACAAACTTTCTGTGTCTGGACCACATCCTCTTCCCATT
GAAAAGCACATTTCACATTTTATGCAAAACATCCCTTTTCCTTCACCACAAAGACCGAGAATCCTTGTCCAGCTGTCAGTCCATGATGCA
TTAATATTATCACAGCCAGTTTCTACACCTTTACCACTAAGTGGAGCCAACTTTAGCACCTTGCTAATGAATCTGGGTCCTGAGAATTGT
GCAACACTGCTGCTCTTTGTTTTACTTGAGAGTAAAATTCTGCTGCATTCTCTTAGGCCAGCTGTCTTGACTGGGGTAGCTGAAGCTGTT
GTAGCTATGATCTTTCCATTTCAGTGGCAATGCCCATATATTCCCCTTTGTCCTCTTTCACTGGCTGCAGTGCTTAGTGCACCTTTACCA
TTTATAGTTGGAGTTGACTCAAGGTATTTTGATCTTCATGACCCACCACAAGATGTTGTTTGCATTGACTTGGATACGAACATGTTATAT
GTATCAGATGAAAAGAAGAACATGAACTGGAAGCAACTTCCCAAAAAGCCGTGCAAAAATCTACTTAGCACCTTAAAGAAATTGTATCCC
CAGCTGTCTTCAGTTCACCAAAAAACTCAAGAAGGCTCAGCGATTGACATGACTCCAATTGAAGCAGATTTCTCCTGGCAAAAGAAGATG
ACACAGCTTGAGATGGAAATTCAAGAGGCATTTTTGCGCTTTATGGCGTCTATTTTAAAAGGATATAGAACATATCTCAGACCAATCACA
GAGGCTCCTTCAAATAAAGCCACAGCTGCTGATTCATTGTTTGACCGACAGGGATTTTTAAAAAGTCGAGATCGTGCCTATGCAAAATTC
TATACCCTTTTATCCAAAACACAGATTTTTATTCGTTTCATTGAAGAATGCAGTTTTGTAAGTGATAAAGATACTGGATTAGCATTTTTT
GATGACTGCATAGAAAAGTTGTTTCCTGATAAAGGCACAGAGAAAACAGATAAGGTTGATTTTGATTCAGCAGAAGATACCAGATTGATA
GAACTAGATGATTCACAGAAAAGTGAGCATACTGTATTTATAATGCCGCCAGAGCCACCTCCTGATGATGGAAAGGACCTGTCACCAAAG
TACAGTTACAAATACTTTCCAAGACTGGACCTTAAGCTTTTTGACAGACCGCAGGAGTTGAAACTTTGTTTTAGTAGACACCCTACTGGG
AATAGCATTACAAAGAGTCCACCTCTCATGGCTAAGAGAACTAAACAGGAAATAAAAACAGCTCATAAATTGGCGAAGAGATGTTATACA
AATCCACCACAGTGGGCCAAGTGTCTGTTTAGTCATTGTTACAGTTTATGGTTTATTTGTCTTCCGGCCTATGTTAGAGTTTCTCATCCT
AAAGTCAGAGCACTTCAGCAGGCATATGATGTACTTATTAAGATGAGGAAAACAGATGTGGATCCCTTAGATGAGGTGTGCTATCGAGTA
GTGATGCAGCTTTGTGGACTTTGGGGTCATCCTGTTTTAGCAGTGAGAGTCTTATTTGAAATGAAAACTGCTAGGATAAAGCCTAATGCT
ATTACTTATGGTTATTATAATAAGGTAGTCTTGGAGAGCCCGTGGCCTAGCAGTACCCGCAGTGGTATTTTCTTATGGACGAAGGTACGG
AATGTGGTACGTGGCTTGGCACAGTTTAGGCAGCCGCTTAAAAAGACTGTGCAAAGGTCACAGGTCTCCTCAATATCAGGTGGTCAGTCT
GACCAAGGATACGGGTCTAAGGATGAACTTATAAAGGATGATGCAGAAATTCATGTGCCTGAAGAACAGGCAGCAAGAGAATTGATAACT
AAAACAAAAATGCAAACAGAAGAGGTGTGTGATGCCTCTGCTATTGTGGCAAAACATTCACAACCTAGTCCAGAGCCTCACAGTCCTACT
GAACCTCCTGCATGGGGCAGCAGTATTGTGAAAGTTCCGTCTGGTATATTTGATGTCAACAGCAGGAAAAGTAGCACTGGTAGTATATCA
AATGTGCTGTTTTCTACTCAAGATCCAGTTGAAGATGCAGTCTTTGGCGAAGCTACTAATCTCAAGAAGAATGGTGATAGAGGAGAAAAA
AGACAAAAGCATTTTCCTGAGAGGAGTTGTAGTTTTAGTTCTGAAAGTCGAGCAGGAATGTTGCTTAAGAAGAGTAGTTTGGATTCGAAT
TCAAGTGAAATGGCTATCATGATGGGAGCAGATGCCAAGATTCTCACAGCAGCATTGACATGTCCTAAGACTTCTCTACTTCATATTGCA
AGAACCCATAGCTTTGAGAATGTTAGCTGTCACCTACCTGATAGTAGGACTTGTATGTCTGAAAGCACTTGGAATCCTGAGCACAGATCA
TCTCCGGTGCCAGAGATGCTTGAGGAAAGCCAAGAACTCCTTGAGCCTGTGGTTGATGACGTACCTAAAACTACTGCAACAGTAGATACA
TATGAGAGTCTACTAAGTGATAGTAACAGTAATCAGTCCAGAGACTTGAAAACAGTATCCAAAGATCTGAGGAATAAGAGAAGTAGTTTA
TATGGTATTGCTAAGGTGGTTCAGAGGGAAGATGTTGAAACTGGACTAGATCCTTTGTCTCTTTTAGCCACTGAATGTACAGGAGGAAAA
ACTCCTGATTCTGAAGATAAGTTGTTTTCTCCAGTTATTGCACGTAATCTGGCTGATGAAATAGAAAGCTATATGAACCTAAAAAGTCCC
CTAGGTAGTAAATCTTCTAGTATGGAATTACACAGAGAGGAAAACAGAGAGTCTGGCATGACTACTGCATTTATTCATGCTCTAGAGAGG
AGATCAAGCCTACCTTTAGATCATGGTTCACCAGCACAGGAAAATCCTGAAAGTGAAAAGAGCTCACCTGCAGTGTCCAGGTCTAAAACT
TTTACTGGGCGTTTCAAGCAGCAAACCCCCTCTCGAACTCATAAAGAACGTTCAACTTCTTTGTCAGCACTGGTGCGTTCTTCGCCACAT
GGCTCGTTGGGTTCTGTAGTAAATTCTTTGTCAGGGCTAAAGCTGGATAATATACTCTCAGGGCCCAAGATAGATGTCCTGAAATCTGGT
ATGAAACAAGCAGCGACAGTAGCCAGTAAGATGTGGGTAGCTGTTGCGTCTGCCTACAGCTACTCAGATGATGAGGAAGAAACTAATAGA
GACTACAGCTTCCCAGCTGGCCTAGAAGACCATATTTTGGGGGAGAATATATCGCCTAACACAAGTATCTCAGGGTTGGTCCCCAGTGAA
CTTACCCAGAGCAACACAAGTCTTGGCAGTAGCAGCAGTAGTGGAGATGTAGGAAAACTGCATTATCCAACAGGTGAAGTTCCATTTCCA
AGAGGCATGAAAGGGCAAGACTTTGAAAAATCAGATCATGGTTCTTCTCAAAATACCAGCATGTCTAGCATCTATCAGAATTGTGCAATG
GAGGTTTTGATGTCCAGTTGTTCACAGTGTAGAGCTTGTGGAGCTTTAGTTTATGATGAAGAAATTATGGCTGGATGGACAGCAGATGAC
TCAAATTTGAATACAGCTTGTCCATTCTGTAAAAGCAACTTCTTGCCTCTTCTCAATATAGAATTCAAAGATTTGAGAGGTTCTGCAAGC
TTTTTCCTGAAACCAAGTACCTCTGGTGACAGTTTACAAAGTGGAAGCATTCCATTGGCAAATGAATCCTTGGAGCACAAACCTGTATCC
AGTTTAGCAGAACCTGACTTGATCAACTTTATGGACTTCCCAAAACATAACCAGATCATAACTGAAGAAACAGGCTCTGCAGTTGAACCA
AGGTCCCGTTTAATGGATTCTGACATGGATTATGAAAGGCCAAACGTAGAGACCATCAAGTGCGTTGTGGTGGGGGACAACGCCGTGGGT
AAGACCAGGCTCATCTGTGCCCGCGCTTGCAATGCCACCCTCACCCAGTACCAGCTGCTGGCCACGCATGTGCCCACAGTATGGGCCATC
GACCAATATCGTGTGTGCCAGGAGGTGCTGGAACGCTCCCGAGACGTGGTAGATGATGTCAGCGTCTCTCTGCGCCTCTGGGACACCTTT
GGAGACCACCACAAAGACCGTCGCTTTGCTTATGGGAGATCTGATGTGGTGGTTCTGTGCTTCTCCATTGCCAACCCCAATTCCCTCCAC
CATGTCAAGACCATGTGGTACCCAGAAATCAAGCACTTCTGCCCCCGAGCACCTGTCATCTTGGTGGGCTGCCAGTTGGACCTGCGCTAC
GCTGACCTGGAGGCTGTCAACAGGGCTAGGCGACCCTTGGCTAGGCCCATCAAACCTAATGAAATCCTGCCCCCAGAGAAGGGTCGGGAG
GTGGCCAAGGAGCTGGGCATCCCCTACTATGAGACCAGCGTGGTGGCCCAGTTCGGCATCAAGGACGTCTTTGACAACGCCATCCGAGCT
GCACTCATCTCCCGCCGCCACCTGCAGTTCTGGAAGTCCCACCTCCGCAATGTGCAGCGGCCTCTGCTGCAGGCACCCTTCCTACCCCCC
AAGCCACCGCCCCCGATCATCGTGGTGCCCGACCCTCCCTCCAGCAGCGAGGAGTGCCCCGCCCACCTCCTGGAGGACCCGCTCTGCGCG
GACGTCATCCTGGTGCTGCAGGAGCGGGTGCGCATCTTTGCCCACAAGATCTACCTCTCCACCTCTTCCTCCAAGTTCTATGACCTGTTC
CTCATGGACCTGAGTGAGGGGGAGCTGGGGGGCCCCTCGGAGCCAGGGGGCACCCACCCAGAGGACCACCAGGGCCACTCTGATCAACAC
CACCACCATCACCACCACCACCATGGGCGAGACTTCCTGCTCCGAGCAGCCAGCTTTGACGTGTGCGAGAGCGTGGATGAGGCTGGGGGC
TCCGGTCCTGCTGGCCTCCGTGCTTCCACCAGCGACGGGATCTTACGGGGCAACGGAACAGGGTACCTACCGGGCAGGGGTCGTGTGCTG
TCTTCCTGGAGCCGAGCTTTTGTGAGCATCCAGGAAGAGATGGCAGAAGATCCTCTCACCTACAAATCCCGGCTGATGGTGGTGGTGAAG
ATGGACAGTTCCATCCAGCCGGGGCCCTTCCGGGCTGTCCTCAAGTACCTGTACACGGGGGAGCTAGATGAGAACGAGCGTGACCTCATG
CACATTGCCCACATTGCTGAGCTGCTCGAGGTCTTTGATCTGCGCATGATGGTGGCCAACATTCTCAACAATGAGGCCTTCATGAACCAG
GAGATCACCAAGGCCTTCCACGTCCGCCGGACCAACCGGGTTAAGGAGTGCTTGGCAAAAGGCACCTTCTCAGATGTGACCTTCATCCTG
GATGATGGCACCATCAGCGCCCACAAGCCCCTGTTGATTTCCAGCTGTGACTGGATGGCTGCCATGTTTGGGGGGCCATTTGTGGAGAGC
TCCACCCGGGAGGTGGTGTTTCCCTACACAAGCAAGAGCTGCATGCGGGCCGTGCTGGAATACCTCTACACCGGCATGTTCACCTCCAGC
CCCGACCTGGATGACATGAAGCTCATCATTCTAGCCAACCGCCTCTGCCTGCCACACCTGGTTGCCCTCACAGAGCAGTACACAGTGACC
GGGCTGATGGAAGCGACCCAGATGATGGTGGACATCGATGGGGACGTCCTTGTGTTCCTGGAACTGGCTCAGTTCCACTGTGCGTACCAG
CTGGCCGACTGGTGTCTCCACCACATCTGCACCAACTACAACAACGTGTGCCGCAAGTTCCCCCGAGACATGAAGGCCATGTCCCCAGAA
AACCAGGAGTATTTCGAGAAGCATCGGTGGCCACCTGTGTGGTACCTGAAGGAGGAAGATCATTACCAGCGGGCACGGAAGGAGCGTGAG
AAGGAGGACTACCTCCACCTCAAGCGGCAGCCCAAACGGCGTTGGCTCTTCTGGAACAGTCCATCCTCCCCGTCTTCCTCGGCAGCCTCC
TCCTCATCCCCATCTTCCTCCTCGGCTGTGGTCTGAGATGCTGCCACCCTCTTCTGACCCTGCTGCTGTTGTCCCCATCCGCCTTCACCC
CTCTGCTCTTCCGCATCACCCCATCCACCTTACAGGGACCAGGGGGCCCACGTAACCAGGACCCAGAGGGTGGAGCTCTTCTTACCAGCC
ACCGTGGCTCAGCCAGAGAGGAGCTGAGCCCTGTGGAGCAGAACGGGAACCACCTGCAGAGGTCCCCAGACCCAAAGCAGGACGGGAGAC
AACTGCTTGGAGGAGCGAAGAGCCCTGGCATTTTATCTCTGGGTTTGAGAGCCCTAGAGTCAAAGGGAAAGCCTCCCAGCCTCCAGGGCT
TCTCTGTGTGTCTTGGTTGCTGCTCTGGCCAGGGAGGCAGCCCCACTCCCAGCAAGCAGAAGTGATCCTCGAGGGTCCTGCCCCTGTTGG
CCATATCTTTCCACCGACGGACTTGAGTGTTGCATTTGTTTTGTGGGCATTTCCACACGAAGCCTACTCACACCCTCACTGGAGAAGTCA
GGGTAGAAATTGAGCCTTCAGAGCCCAACTCAAGGCTTCTACATCCTGGGGTGCAGCTGCAAAAGGCCAGACGTGGAAAGGCCTGTATCC
TGCCAGTGTCCCTCCGTCCCAGGGGGCTGTGCTAGCACAGACCTGAGAATGGGGACACAGGTCATTCAGAGCTCCAGGCCTGGAAGCAGT
GCCTCTTGGTGCAACAAGAAACTTCTCCCTCACCCCCTCCTTTACCCTCAGATTTGGAGATGGTAACCAAAGGAAGCAGCTGGGACAGGT
GGAGAAGGAAGTAGGAATGAGTGCACGGCGACCCCGTGCTCCTCAGGGCCCTCCCCTGCCTCTGGGTGGCACTGCTTTTTATAGGGTGGG
GCAAAATTAGCAAAAAACAAAAACCAATGACAACCAAACTGAAACCGAAACGAAAAATCAACAAACACTCTGTCCTCTATCCCTCCAAAG

>22263_22263_3_DENND4C-RHOBTB2_DENND4C_chr9_19357152_ENST00000380432_RHOBTB2_chr8_22861938_ENST00000519685_length(amino acids)=2100AA_BP=1362
MGATIECWDPETKYPLPVFSTFVLTGSSAKKVYGAAIQFYEPYSRELLSEKQLMHLGLLTPVERKMVSKSINTNKCICLLSHWPFFEAFR
KFLMFIYKLSVSGPHPLPIEKHISHFMQNIPFPSPQRPRILVQLSVHDALILSQPVSTPLPLSGANFSTLLMNLGPENCATLLLFVLLES
KILLHSLRPAVLTGVAEAVVAMIFPFQWQCPYIPLCPLSLAAVLSAPLPFIVGVDSRYFDLHDPPQDVVCIDLDTNMLYVSDEKKNMNWK
QLPKKPCKNLLSTLKKLYPQLSSVHQKTQEGSAIDMTPIEADFSWQKKMTQLEMEIQEAFLRFMASILKGYRTYLRPITEAPSNKATAAD
SLFDRQGFLKSRDRAYAKFYTLLSKTQIFIRFIEECSFVSDKDTGLAFFDDCIEKLFPDKGTEKTDKVDFDSAEDTRLIELDDSQKSEHT
VFIMPPEPPPDDGKDLSPKYSYKYFPRLDLKLFDRPQELKLCFSRHPTGNSITKSPPLMAKRTKQEIKTAHKLAKRCYTNPPQWAKCLFS
HCYSLWFICLPAYVRVSHPKVRALQQAYDVLIKMRKTDVDPLDEVCYRVVMQLCGLWGHPVLAVRVLFEMKTARIKPNAITYGYYNKVVL
ESPWPSSTRSGIFLWTKVRNVVRGLAQFRQPLKKTVQRSQVSSISGGQSDQGYGSKDELIKDDAEIHVPEEQAARELITKTKMQTEEVCD
ASAIVAKHSQPSPEPHSPTEPPAWGSSIVKVPSGIFDVNSRKSSTGSISNVLFSTQDPVEDAVFGEATNLKKNGDRGEKRQKHFPERSCS
FSSESRAGMLLKKSSLDSNSSEMAIMMGADAKILTAALTCPKTSLLHIARTHSFENVSCHLPDSRTCMSESTWNPEHRSSPVPEMLEESQ
ELLEPVVDDVPKTTATVDTYESLLSDSNSNQSRDLKTVSKDLRNKRSSLYGIAKVVQREDVETGLDPLSLLATECTGGKTPDSEDKLFSP
VIARNLADEIESYMNLKSPLGSKSSSMELHREENRESGMTTAFIHALERRSSLPLDHGSPAQENPESEKSSPAVSRSKTFTGRFKQQTPS
RTHKERSTSLSALVRSSPHGSLGSVVNSLSGLKLDNILSGPKIDVLKSGMKQAATVASKMWVAVASAYSYSDDEEETNRDYSFPAGLEDH
ILGENISPNTSISGLVPSELTQSNTSLGSSSSSGDVGKLHYPTGEVPFPRGMKGQDFEKSDHGSSQNTSMSSIYQNCAMEVLMSSCSQCR
ACGALVYDEEIMAGWTADDSNLNTACPFCKSNFLPLLNIEFKDLRGSASFFLKPSTSGDSLQSGSIPLANESLEHKPVSSLAEPDLINFM
DFPKHNQIITEETGSAVEPRSRLMDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLE
RSRDVVDDVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARR
PLARPIKPNEILPPEKGREVAKELGIPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQAPFLPPKPPPPIIVVPD
PPSSSEECPAHLLEDPLCADVILVLQERVRIFAHKIYLSTSSSKFYDLFLMDLSEGELGGPSEPGGTHPEDHQGHSDQHHHHHHHHHGRD
FLLRAASFDVCESVDEAGGSGPAGLRASTSDGILRGNGTGYLPGRGRVLSSWSRAFVSIQEEMAEDPLTYKSRLMVVVKMDSSIQPGPFR
AVLKYLYTGELDENERDLMHIAHIAELLEVFDLRMMVANILNNEAFMNQEITKAFHVRRTNRVKECLAKGTFSDVTFILDDGTISAHKPL
LISSCDWMAAMFGGPFVESSTREVVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIILANRLCLPHLVALTEQYTVTGLMEATQMMVD
IDGDVLVFLELAQFHCAYQLADWCLHHICTNYNNVCRKFPRDMKAMSPENQEYFEKHRWPPVWYLKEEDHYQRARKEREKEDYLHLKRQP

--------------------------------------------------------------
>22263_22263_4_DENND4C-RHOBTB2_DENND4C_chr9_19357152_ENST00000380432_RHOBTB2_chr8_22861938_ENST00000522948_length(transcript)=9059nt_BP=4142nt
TCAGAATCAGATGTACCTCTTTTCTGCCTTCCTATGGGAGCTACTATTGAGTGCTGGGATCCTGAAACCAAATATCCACTTCCAGTTTTT
TCAACTTTTGTCTTGACAGGTTCTTCAGCCAAAAAGGTATATGGAGCTGCCATTCAGTTTTATGAACCTTACTCTCGGGAACTTCTATCA
GAGAAACAGCTTATGCACCTGGGCTTGTTGACGCCTGTGGAGAGAAAAATGGTCTCCAAATCCATCAATACAAACAAATGCATTTGTTTA
CTCTCACACTGGCCTTTTTTTGAAGCTTTTAGGAAATTTCTTATGTTTATCTACAAACTTTCTGTGTCTGGACCACATCCTCTTCCCATT
GAAAAGCACATTTCACATTTTATGCAAAACATCCCTTTTCCTTCACCACAAAGACCGAGAATCCTTGTCCAGCTGTCAGTCCATGATGCA
TTAATATTATCACAGCCAGTTTCTACACCTTTACCACTAAGTGGAGCCAACTTTAGCACCTTGCTAATGAATCTGGGTCCTGAGAATTGT
GCAACACTGCTGCTCTTTGTTTTACTTGAGAGTAAAATTCTGCTGCATTCTCTTAGGCCAGCTGTCTTGACTGGGGTAGCTGAAGCTGTT
GTAGCTATGATCTTTCCATTTCAGTGGCAATGCCCATATATTCCCCTTTGTCCTCTTTCACTGGCTGCAGTGCTTAGTGCACCTTTACCA
TTTATAGTTGGAGTTGACTCAAGGTATTTTGATCTTCATGACCCACCACAAGATGTTGTTTGCATTGACTTGGATACGAACATGTTATAT
GTATCAGATGAAAAGAAGAACATGAACTGGAAGCAACTTCCCAAAAAGCCGTGCAAAAATCTACTTAGCACCTTAAAGAAATTGTATCCC
CAGCTGTCTTCAGTTCACCAAAAAACTCAAGAAGGCTCAGCGATTGACATGACTCCAATTGAAGCAGATTTCTCCTGGCAAAAGAAGATG
ACACAGCTTGAGATGGAAATTCAAGAGGCATTTTTGCGCTTTATGGCGTCTATTTTAAAAGGATATAGAACATATCTCAGACCAATCACA
GAGGCTCCTTCAAATAAAGCCACAGCTGCTGATTCATTGTTTGACCGACAGGGATTTTTAAAAAGTCGAGATCGTGCCTATGCAAAATTC
TATACCCTTTTATCCAAAACACAGATTTTTATTCGTTTCATTGAAGAATGCAGTTTTGTAAGTGATAAAGATACTGGATTAGCATTTTTT
GATGACTGCATAGAAAAGTTGTTTCCTGATAAAGGCACAGAGAAAACAGATAAGGTTGATTTTGATTCAGCAGAAGATACCAGATTGATA
GAACTAGATGATTCACAGAAAAGTGAGCATACTGTATTTATAATGCCGCCAGAGCCACCTCCTGATGATGGAAAGGACCTGTCACCAAAG
TACAGTTACAAATACTTTCCAAGACTGGACCTTAAGCTTTTTGACAGACCGCAGGAGTTGAAACTTTGTTTTAGTAGACACCCTACTGGG
AATAGCATTACAAAGAGTCCACCTCTCATGGCTAAGAGAACTAAACAGGAAATAAAAACAGCTCATAAATTGGCGAAGAGATGTTATACA
AATCCACCACAGTGGGCCAAGTGTCTGTTTAGTCATTGTTACAGTTTATGGTTTATTTGTCTTCCGGCCTATGTTAGAGTTTCTCATCCT
AAAGTCAGAGCACTTCAGCAGGCATATGATGTACTTATTAAGATGAGGAAAACAGATGTGGATCCCTTAGATGAGGTGTGCTATCGAGTA
GTGATGCAGCTTTGTGGACTTTGGGGTCATCCTGTTTTAGCAGTGAGAGTCTTATTTGAAATGAAAACTGCTAGGATAAAGCCTAATGCT
ATTACTTATGGTTATTATAATAAGGTAGTCTTGGAGAGCCCGTGGCCTAGCAGTACCCGCAGTGGTATTTTCTTATGGACGAAGGTACGG
AATGTGGTACGTGGCTTGGCACAGTTTAGGCAGCCGCTTAAAAAGACTGTGCAAAGGTCACAGGTCTCCTCAATATCAGGTGGTCAGTCT
GACCAAGGATACGGGTCTAAGGATGAACTTATAAAGGATGATGCAGAAATTCATGTGCCTGAAGAACAGGCAGCAAGAGAATTGATAACT
AAAACAAAAATGCAAACAGAAGAGGTGTGTGATGCCTCTGCTATTGTGGCAAAACATTCACAACCTAGTCCAGAGCCTCACAGTCCTACT
GAACCTCCTGCATGGGGCAGCAGTATTGTGAAAGTTCCGTCTGGTATATTTGATGTCAACAGCAGGAAAAGTAGCACTGGTAGTATATCA
AATGTGCTGTTTTCTACTCAAGATCCAGTTGAAGATGCAGTCTTTGGCGAAGCTACTAATCTCAAGAAGAATGGTGATAGAGGAGAAAAA
AGACAAAAGCATTTTCCTGAGAGGAGTTGTAGTTTTAGTTCTGAAAGTCGAGCAGGAATGTTGCTTAAGAAGAGTAGTTTGGATTCGAAT
TCAAGTGAAATGGCTATCATGATGGGAGCAGATGCCAAGATTCTCACAGCAGCATTGACATGTCCTAAGACTTCTCTACTTCATATTGCA
AGAACCCATAGCTTTGAGAATGTTAGCTGTCACCTACCTGATAGTAGGACTTGTATGTCTGAAAGCACTTGGAATCCTGAGCACAGATCA
TCTCCGGTGCCAGAGATGCTTGAGGAAAGCCAAGAACTCCTTGAGCCTGTGGTTGATGACGTACCTAAAACTACTGCAACAGTAGATACA
TATGAGAGTCTACTAAGTGATAGTAACAGTAATCAGTCCAGAGACTTGAAAACAGTATCCAAAGATCTGAGGAATAAGAGAAGTAGTTTA
TATGGTATTGCTAAGGTGGTTCAGAGGGAAGATGTTGAAACTGGACTAGATCCTTTGTCTCTTTTAGCCACTGAATGTACAGGAGGAAAA
ACTCCTGATTCTGAAGATAAGTTGTTTTCTCCAGTTATTGCACGTAATCTGGCTGATGAAATAGAAAGCTATATGAACCTAAAAAGTCCC
CTAGGTAGTAAATCTTCTAGTATGGAATTACACAGAGAGGAAAACAGAGAGTCTGGCATGACTACTGCATTTATTCATGCTCTAGAGAGG
AGATCAAGCCTACCTTTAGATCATGGTTCACCAGCACAGGAAAATCCTGAAAGTGAAAAGAGCTCACCTGCAGTGTCCAGGTCTAAAACT
TTTACTGGGCGTTTCAAGCAGCAAACCCCCTCTCGAACTCATAAAGAACGTTCAACTTCTTTGTCAGCACTGGTGCGTTCTTCGCCACAT
GGCTCGTTGGGTTCTGTAGTAAATTCTTTGTCAGGGCTAAAGCTGGATAATATACTCTCAGGGCCCAAGATAGATGTCCTGAAATCTGGT
ATGAAACAAGCAGCGACAGTAGCCAGTAAGATGTGGGTAGCTGTTGCGTCTGCCTACAGCTACTCAGATGATGAGGAAGAAACTAATAGA
GACTACAGCTTCCCAGCTGGCCTAGAAGACCATATTTTGGGGGAGAATATATCGCCTAACACAAGTATCTCAGGGTTGGTCCCCAGTGAA
CTTACCCAGAGCAACACAAGTCTTGGCAGTAGCAGCAGTAGTGGAGATGTAGGAAAACTGCATTATCCAACAGGTGAAGTTCCATTTCCA
AGAGGCATGAAAGGGCAAGACTTTGAAAAATCAGATCATGGTTCTTCTCAAAATACCAGCATGTCTAGCATCTATCAGAATTGTGCAATG
GAGGTTTTGATGTCCAGTTGTTCACAGTGTAGAGCTTGTGGAGCTTTAGTTTATGATGAAGAAATTATGGCTGGATGGACAGCAGATGAC
TCAAATTTGAATACAGCTTGTCCATTCTGTAAAAGCAACTTCTTGCCTCTTCTCAATATAGAATTCAAAGATTTGAGAGGTTCTGCAAGC
TTTTTCCTGAAACCAAGTACCTCTGGTGACAGTTTACAAAGTGGAAGCATTCCATTGGCAAATGAATCCTTGGAGCACAAACCTGTATCC
AGTTTAGCAGAACCTGACTTGATCAACTTTATGGACTTCCCAAAACATAACCAGATCATAACTGAAGAAACAGGCTCTGCAGTTGAACCA
AGGTCCCGTTTAATGGATTCTGACATGGATTATGAAAGGCCAAACGTAGAGACCATCAAGTGCGTTGTGGTGGGGGACAACGCCGTGGGT
AAGACCAGGCTCATCTGTGCCCGCGCTTGCAATGCCACCCTCACCCAGTACCAGCTGCTGGCCACGCATGTGCCCACAGTATGGGCCATC
GACCAATATCGTGTGTGCCAGGAGGTGCTGGAACGCTCCCGAGACGTGGTAGATGATGTCAGCGTCTCTCTGCGCCTCTGGGACACCTTT
GGAGACCACCACAAAGACCGTCGCTTTGCTTATGGGAGATCTGATGTGGTGGTTCTGTGCTTCTCCATTGCCAACCCCAATTCCCTCCAC
CATGTCAAGACCATGTGGTACCCAGAAATCAAGCACTTCTGCCCCCGAGCACCTGTCATCTTGGTGGGCTGCCAGTTGGACCTGCGCTAC
GCTGACCTGGAGGCTGTCAACAGGGCTAGGCGACCCTTGGCTAGGCCCATCAAACCTAATGAAATCCTGCCCCCAGAGAAGGGTCGGGAG
GTGGCCAAGGAGCTGGGCATCCCCTACTATGAGACCAGCGTGGTGGCCCAGTTCGGCATCAAGGACGTCTTTGACAACGCCATCCGAGCT
GCACTCATCTCCCGCCGCCACCTGCAGTTCTGGAAGTCCCACCTCCGCAATGTGCAGCGGCCTCTGCTGCAGGCACCCTTCCTACCCCCC
AAGCCACCGCCCCCGATCATCGTGGTGCCCGACCCTCCCTCCAGCAGCGAGGAGTGCCCCGCCCACCTCCTGGAGGACCCGCTCTGCGCG
GACGTCATCCTGGTGCTGCAGGAGCGGGTGCGCATCTTTGCCCACAAGATCTACCTCTCCACCTCTTCCTCCAAGTTCTATGACCTGTTC
CTCATGGACCTGAGTGAGGGGGAGCTGGGGGGCCCCTCGGAGCCAGGGGGCACCCACCCAGAGGACCACCAGGGCCACTCTGATCAACAC
CACCACCATCACCACCACCACCATGGGCGAGACTTCCTGCTCCGAGCAGCCAGCTTTGACGTGTGCGAGAGCGTGGATGAGGCTGGGGGC
TCCGGTCCTGCTGGCCTCCGTGCTTCCACCAGCGACGGGATCTTACGGGGCAACGGAACAGGGTACCTACCGGGCAGGGGTCGTGTGCTG
TCTTCCTGGAGCCGAGCTTTTGTGAGCATCCAGGAAGAGATGGCAGAAGATCCTCTCACCTACAAATCCCGGCTGATGGTGGTGGTGAAG
ATGGACAGTTCCATCCAGCCGGGGCCCTTCCGGGCTGTCCTCAAGTACCTGTACACGGGGGAGCTAGATGAGAACGAGCGTGACCTCATG
CACATTGCCCACATTGCTGAGCTGCTCGAGGTCTTTGATCTGCGCATGATGGTGGCCAACATTCTCAACAATGAGGCCTTCATGAACCAG
GAGATCACCAAGGCCTTCCACGTCCGCCGGACCAACCGGGTTAAGGAGTGCTTGGCAAAAGGCACCTTCTCAGATGTGACCTTCATCCTG
GATGATGGCACCATCAGCGCCCACAAGCCCCTGTTGATTTCCAGCTGTGACTGGATGGCTGCCATGTTTGGGGGGCCATTTGTGGAGAGC
TCCACCCGGGAGGTGGTGTTTCCCTACACAAGCAAGAGCTGCATGCGGGCCGTGCTGGAATACCTCTACACCGGCATGTTCACCTCCAGC
CCCGACCTGGATGACATGAAGCTCATCATTCTAGCCAACCGCCTCTGCCTGCCACACCTGGTTGCCCTCACAGAGCAGTACACAGTGACC
GGGCTGATGGAAGCGACCCAGATGATGGTGGACATCGATGGGGACGTCCTTGTGTTCCTGGAACTGGCTCAGTTCCACTGTGCGTACCAG
CTGGCCGACTGGTGTCTCCACCACATCTGCACCAACTACAACAACGTGTGCCGCAAGTTCCCCCGAGACATGAAGGCCATGTCCCCAGAA
AACCAGGAGTATTTCGAGAAGCATCGGTGGCCACCTGTGTGGTACCTGAAGGAGGAAGATCATTACCAGCGGGCACGGAAGGAGCGTGAG
AAGGAGGACTACCTCCACCTCAAGCGGCAGCCCAAACGGCGTTGGCTCTTCTGGAACAGTCCATCCTCCCCGTCTTCCTCGGCAGCCTCC
TCCTCATCCCCATCTTCCTCCTCGGCTGTGGTCTGAGATGCTGCCACCCTCTTCTGACCCTGCTGCTGTTGTCCCCATCCGCCTTCACCC
CTCTGCTCTTCCGCATCACCCCATCCACCTTACAGGGACCAGGGGGCCCACGTAACCAGGACCCAGAGGGTGGAGCTCTTCTTACCAGCC
ACCGTGGCTCAGCCAGAGAGGAGCTGAGCCCTGTGGAGCAGAACGGGAACCACCTGCAGAGGTCCCCAGACCCAAAGCAGGACGGGAGAC
AACTGCTTGGAGGAGCGAAGAGCCCTGGCATTTTATCTCTGGGTTTGAGAGCCCTAGAGTCAAAGGGAAAGCCTCCCAGCCTCCAGGGCT
TCTCTGTGTGTCTTGGTTGCTGCTCTGGCCAGGGAGGCAGCCCCACTCCCAGCAAGCAGAAGTGATCCTCGAGGGTCCTGCCCCTGTTGG
CCATATCTTTCCACCGACGGACTTGAGTGTTGCATTTGTTTTGTGGGCATTTCCACACGAAGCCTACTCACACCCTCACTGGAGAAGTCA
GGGTAGAAATTGAGCCTTCAGAGCCCAACTCAAGGCTTCTACATCCTGGGGTGCAGCTGCAAAAGGCCAGACGTGGAAAGGCCTGTATCC
TGCCAGTGTCCCTCCGTCCCAGGGGGCTGTGCTAGCACAGACCTGAGAATGGGGACACAGGTCATTCAGAGCTCCAGGCCTGGAAGCAGT
GCCTCTTGGTGCAACAAGAAACTTCTCCCTCACCCCCTCCTTTACCCTCAGATTTGGAGATGGTAACCAAAGGAAGCAGCTGGGACAGGT
GGAGAAGGAAGTAGGAATGAGTGCACGGCGACCCCGTGCTCCTCAGGGCCCTCCCCTGCCTCTGGGTGGCACTGCTTTTTATAGGGTGGG
GCAAAATTAGCAAAAAACAAAAACCAATGACAACCAAACTGAAACCGAAACGAAAAATCAACAAACACTCTGTCCTCTATCCCTCCAAAG
AATGAAAATCAGAAAAAGCCCCTGCCTAGCTCACATTTCTATAAACAGAGGCCCCCATGATGAGGAGGTGAAGATTTAGGTTGCAGAATC
GACTCCAATGCCTTTCAGGAAAGGACTCGGCACTTCTCTGACTGCGGAGGCCCTGACCCTGCCAGCTGGCTCCGAGGGCAACACAGGGGC
CTGGCCTCTAGAGGGCTGGTGATTGAGGGGCCCGGGCTGGCGGCAAAGAGGGGTTTGGTCTCGGGGCTTAAATGGCACCAGACTCTTGCT
TTTGCCCATCTGGAGACTGCAGGCTCCCTTCCTTACCCTCAGAGAGTGCTTATGGTGGGTGTTTTTGCGGGGCTGCAATAGGGGCCAAAA
GTCAGGGAAAGGGGCACTGACCTGTAGTGAAAGGCCACAGGACACAGCCTTATTACTGCTGGGGTGGGATAAGGGGAAGGAGAAGAGGGA
GAATGGAGCAGGAGGAAAAGCAGAGTTGGTCTAGAGAGGAGGAGGGCGGGGCTGGAGGAATGTGGGGGATTGAAACTAGCTCCCAGCCCC
CATGGGGCAGCAGCTGGGCCACAATTGCCCCTTTCCGTTTTCTAACCCCGACTCAGATTTCACCACCCACACTCTTTTTAGGTGTAAAAG
ATGGAGTCCCACGGAGGAGGGGCAGAGCCAGGAGGCAGTGGGGCTGTGGGCTCAGAGCTCAGGAGTCGCCTTACCTGAGAGAGATGTTCT
AGCTGAGAGGGCCTGGCCCTGGGGTGGGCTCCAGGAAAACGCTGGTTAGGCCTGGGATTGAGCTAACCTGAAACAAAGGTAGCAGGCAGG
ACCTAATGACCAGAGGTTAAATCCTCATCAAGAGAGACCAGGCGGCTGGAGGACAAGCGGCTCTAACCCTGGGGGCGGCCATGTTGTCCA
GGCCCAGGCCCCTCCAGGACTGTGGCTGCCTCCCCTCCACGGCCTCCAGGGCGGCTGGCTGGAAAGCCACGCGTATGCTGCCCTCTACAG
GCTGCTCGGCCTCCCTGCAGCTCAGCGCAGCCCAGGGCTCCAAGTGAGGCCCAGAAGCCCATGGGCAGGGCTGGGGGGACGAAGGGGGAA
CCCGGAGCACCTCCACTTCTAGGGAAGATGGACAGCGTGGGGGCACACCTGGGCCTCCCGGAAGCTGTGGACGAAAGGGAGAGCGGGTCC
TCCAGGGCAAGGGGAACGGGAAATAGGTCTCCTAGGTGCCTGAAGCGCTGAGCAACCTGGGTACCCTGGTGGGGATGCAGGGAAGGCCGG
GGCAGAGAAAGTGAAGGTCGACCCAGGGCTGTAGGAAGCCATAGGAGAGTGACCACGGGATTCCCTGAGAAACAGGGCCGGCCCCCCAAC
TTCAGGGACCCACCGCCCATTCCCCGAGAGCTGTCGGAACCAGATGCAACCCGGCAGCCCAGAGAACTCTCCTGGGAGGCTGTGGGTGAG
CCAGGCCAACATTGGTGTCCCTGTCCCCAGAGGGAGGAGCAGGCAGGAGAGAGAGGGGAAGGAGGTATGAATCCCAGTCCCCAGGAACCT
AGCTCTTTAAACTCTGGGGAGTCGGATTCAGGAAACACCCCCAGGAGGCCAAGCCTGAAAACAGAGGGGAGGGAGGAAGGAAGGAGTCCC
AGCAGGAGCACAGCCCTGGTTTCCTGTCACTCAGAGCTGATTCACAGGAGGAGGGGAGGTTGGGGGGCGGGAGACAAAAACCACACCTCT

>22263_22263_4_DENND4C-RHOBTB2_DENND4C_chr9_19357152_ENST00000380432_RHOBTB2_chr8_22861938_ENST00000522948_length(amino acids)=2100AA_BP=1362
MGATIECWDPETKYPLPVFSTFVLTGSSAKKVYGAAIQFYEPYSRELLSEKQLMHLGLLTPVERKMVSKSINTNKCICLLSHWPFFEAFR
KFLMFIYKLSVSGPHPLPIEKHISHFMQNIPFPSPQRPRILVQLSVHDALILSQPVSTPLPLSGANFSTLLMNLGPENCATLLLFVLLES
KILLHSLRPAVLTGVAEAVVAMIFPFQWQCPYIPLCPLSLAAVLSAPLPFIVGVDSRYFDLHDPPQDVVCIDLDTNMLYVSDEKKNMNWK
QLPKKPCKNLLSTLKKLYPQLSSVHQKTQEGSAIDMTPIEADFSWQKKMTQLEMEIQEAFLRFMASILKGYRTYLRPITEAPSNKATAAD
SLFDRQGFLKSRDRAYAKFYTLLSKTQIFIRFIEECSFVSDKDTGLAFFDDCIEKLFPDKGTEKTDKVDFDSAEDTRLIELDDSQKSEHT
VFIMPPEPPPDDGKDLSPKYSYKYFPRLDLKLFDRPQELKLCFSRHPTGNSITKSPPLMAKRTKQEIKTAHKLAKRCYTNPPQWAKCLFS
HCYSLWFICLPAYVRVSHPKVRALQQAYDVLIKMRKTDVDPLDEVCYRVVMQLCGLWGHPVLAVRVLFEMKTARIKPNAITYGYYNKVVL
ESPWPSSTRSGIFLWTKVRNVVRGLAQFRQPLKKTVQRSQVSSISGGQSDQGYGSKDELIKDDAEIHVPEEQAARELITKTKMQTEEVCD
ASAIVAKHSQPSPEPHSPTEPPAWGSSIVKVPSGIFDVNSRKSSTGSISNVLFSTQDPVEDAVFGEATNLKKNGDRGEKRQKHFPERSCS
FSSESRAGMLLKKSSLDSNSSEMAIMMGADAKILTAALTCPKTSLLHIARTHSFENVSCHLPDSRTCMSESTWNPEHRSSPVPEMLEESQ
ELLEPVVDDVPKTTATVDTYESLLSDSNSNQSRDLKTVSKDLRNKRSSLYGIAKVVQREDVETGLDPLSLLATECTGGKTPDSEDKLFSP
VIARNLADEIESYMNLKSPLGSKSSSMELHREENRESGMTTAFIHALERRSSLPLDHGSPAQENPESEKSSPAVSRSKTFTGRFKQQTPS
RTHKERSTSLSALVRSSPHGSLGSVVNSLSGLKLDNILSGPKIDVLKSGMKQAATVASKMWVAVASAYSYSDDEEETNRDYSFPAGLEDH
ILGENISPNTSISGLVPSELTQSNTSLGSSSSSGDVGKLHYPTGEVPFPRGMKGQDFEKSDHGSSQNTSMSSIYQNCAMEVLMSSCSQCR
ACGALVYDEEIMAGWTADDSNLNTACPFCKSNFLPLLNIEFKDLRGSASFFLKPSTSGDSLQSGSIPLANESLEHKPVSSLAEPDLINFM
DFPKHNQIITEETGSAVEPRSRLMDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLE
RSRDVVDDVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARR
PLARPIKPNEILPPEKGREVAKELGIPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQAPFLPPKPPPPIIVVPD
PPSSSEECPAHLLEDPLCADVILVLQERVRIFAHKIYLSTSSSKFYDLFLMDLSEGELGGPSEPGGTHPEDHQGHSDQHHHHHHHHHGRD
FLLRAASFDVCESVDEAGGSGPAGLRASTSDGILRGNGTGYLPGRGRVLSSWSRAFVSIQEEMAEDPLTYKSRLMVVVKMDSSIQPGPFR
AVLKYLYTGELDENERDLMHIAHIAELLEVFDLRMMVANILNNEAFMNQEITKAFHVRRTNRVKECLAKGTFSDVTFILDDGTISAHKPL
LISSCDWMAAMFGGPFVESSTREVVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIILANRLCLPHLVALTEQYTVTGLMEATQMMVD
IDGDVLVFLELAQFHCAYQLADWCLHHICTNYNNVCRKFPRDMKAMSPENQEYFEKHRWPPVWYLKEEDHYQRARKEREKEDYLHLKRQP

--------------------------------------------------------------
>22263_22263_5_DENND4C-RHOBTB2_DENND4C_chr9_19357152_ENST00000434457_RHOBTB2_chr8_22861937_ENST00000519685_length(transcript)=8546nt_BP=5380nt
GGAGGAAAGGGAGAGGGAGGGGGAAAAGAAAGTGCTGTTTTGTGGAAAGGGGCGGAAGGCGGGGGAGAAAAAGGGAACAGAAACATGGCG
GTCAGGTCTTGGGACGGCTGCGCCGCGGGCAGCTCCTAGGCGACGCGCCGCCCGCACTGTCCGACGGCTCACAGCGCGGAGGCACCCGCG
CGGGCCAGCGCTCCGGCCATCGCCCCTGGCTGTAGGCGGCGCCCCTCGGAGACCCTGCCCGCGAGGCGGCGCAGGCGCAGACCGGACTGA
GGCGGCGGCGGCCGCTGGAGCTAGTCCCCCGCCCTGCCCTGCCGAGCGCGCCCAGTCCGCGAATCCGGTGCTTTCTTGCCCCAGGAAGAA
GCCGTGTCGGGGCTGCGCTGACAGAGGAGCAGGCAGCAGAAAATACAGTAGCAGCCATGATAGAAGACAAAGGACCAAGAGTGACAGACT
ACTTTGTCGTAGCTGGTCTCACTGACACATCTACTCTTTTGGATCAAGAAATAAATCGTTTAGATACTAAGTCAACTGGACCTAAAGCTC
CAATTACAGACATTGCCATTATTATCAAATCAGCTGGAGAAACAGTACCTGAAGGTTACACCTGTGTAGAAGCCACTCCATCAGCTCTCC
AAGCAAACTTGAACTATGGAAGTCTGAAAAGCCCAGAACTTTTCCTCTGTTATAAGAGAGGGAGAGATAAACCACCGCTTACAGATATTG
GAGTTCTATATGAAGGGAAAGAACGGCTTATTCCAGGATGTGAAGTGATCCTAGCCACACCCTATGGTCGCTGTGCCAATGTCAACAATA
GTTCAACTACTTCACAAAGAATCTTTATCACTTATCGAAGGGCTCCTCCAGTTCGACCCCAGAATTCCTTGGCTGTAACTGATATCTGTG
TTATTGTAACCAGTAAAGGAGAAACTCCTCCTCATACCTTCTGCAAAGTTGACAAAAACTTAAATTGTGGAATGTGGGGTTCCAGCGTGT
TTCTGTGTTATAAGAAGTCTGTACCTGCTTCAAATGCAATAGCATATAAGGCTGGTTTAATTTTTAGATATCCAGAAGAGGACTATGAGT
CATTTCCACTCTCAGAATCAGATGTACCTCTTTTCTGCCTTCCTATGGGAGCTACTATTGAGTGCTGGGATCCTGAAACCAAATATCCAC
TTCCAGTTTTTTCAACTTTTGTCTTGACAGGTTCTTCAGCCAAAAAGGTATATGGAGCTGCCATTCAGTTTTATGAACCTTACTCTCGGG
AACTTCTATCAGAGAAACAGCTTATGCACCTGGGCTTGTTGACGCCTGTGGAGAGAAAAATGGTCTCCAAATCCATCAATACAAACAAAT
GCATTTGTTTACTCTCACACTGGCCTTTTTTTGAAGCTTTTAGGAAATTTCTTATGTTTATCTACAAACTTTCTGTGTCTGGACCACATC
CTCTTCCCATTGAAAAGCACATTTCACATTTTATGCAAAACATCCCTTTTCCTTCACCACAAAGACCGAGAATCCTTGTCCAGCTGTCAG
TCCATGATGCATTAATATTATCACAGCCAGTTTCTACACCTTTACCACTAAGTGGAGCCAACTTTAGCACCTTGCTAATGAATCTGGGTC
CTGAGAATTGTGCAACACTGCTGCTCTTTGTTTTACTTGAGAGTAAAATTCTGCTGCATTCTCTTAGGCCAGCTGTCTTGACTGGGGTAG
CTGAAGCTGTTGTAGCTATGATCTTTCCATTTCAGTGGCAATGCCCATATATTCCCCTTTGTCCTCTTTCACTGGCTGCAGTGCTTAGTG
CACCTTTACCATTTATAGTTGGAGTTGACTCAAGGTATTTTGATCTTCATGACCCACCACAAGATGTTGTTTGCATTGACTTGGATACGA
ACATGTTATATGTATCAGATGAAAAGAAGAACATGAACTGGAAGCAACTTCCCAAAAAGCCGTGCAAAAATCTACTTAGCACCTTAAAGA
AATTGTATCCCCAGCTGTCTTCAGTTCACCAAAAAACTCAAGAAGGCTCAGCGATTGACATGACTCCAATTGAAGCAGATTTCTCCTGGC
AAAAGAAGATGACACAGCTTGAGATGGAAATTCAAGAGGCATTTTTGCGCTTTATGGCGTCTATTTTAAAAGGATATAGAACATATCTCA
GACCAATCACAGAGGCTCCTTCAAATAAAGCCACAGCTGCTGATTCATTGTTTGACCGACAGGGATTTTTAAAAAGTCGAGATCGTGCCT
ATGCAAAATTCTATACCCTTTTATCCAAAACACAGATTTTTATTCGTTTCATTGAAGAATGCAGTTTTGTAAGTGATAAAGATACTGGAT
TAGCATTTTTTGATGACTGCATAGAAAAGTTGTTTCCTGATAAAGGCACAGAGAAAACAGATAAGGTTGATTTTGATTCAGCAGAAGATA
CCAGATTGATAGAACTAGATGATTCACAGAAAAGTGAGCATACTGTATTTATAATGCCGCCAGAGCCACCTCCTGATGATGGAAAGGACC
TGTCACCAAAGTACAGTTACAAATACTTTCCAAGACTGGACCTTAAGCTTTTTGACAGACCGCAGGAGTTGAAACTTTGTTTTAGTAGAC
ACCCTACTGGGAATAGCATTACAAAGAGTCCACCTCTCATGGCTAAGAGAACTAAACAGGAAATAAAAACAGCTCATAAATTGGCGAAGA
GATGTTATACAAATCCACCACAGTGGGCCAAGTGTCTGTTTAGTCATTGTTACAGTTTATGGTTTATTTGTCTTCCGGCCTATGTTAGAG
TTTCTCATCCTAAAGTCAGAGCACTTCAGCAGGCATATGATGTACTTATTAAGATGAGGAAAACAGATGTGGATCCCTTAGATGAGGTGT
GCTATCGAGTAGTGATGCAGCTTTGTGGACTTTGGGGTCATCCTGTTTTAGCAGTGAGAGTCTTATTTGAAATGAAAACTGCTAGGATAA
AGCCTAATGCTATTACTTATGGTTATTATAATAAGGTAGTCTTGGAGAGCCCGTGGCCTAGCAGTACCCGCAGTGGTATTTTCTTATGGA
CGAAGGTACGGAATGTGGTACGTGGCTTGGCACAGTTTAGGCAGCCGCTTAAAAAGACTGTGCAAAGGTCACAGGTCTCCTCAATATCAG
CTCTTCAAAATGTCACAGGTGGAAGTGATGGGGACACGGTGAGCCACGGTAGTGTGGATAGTTCTAATGATGCTAACAATGGGGAGCACA
CAGTCTTCGTCAGAGATTTAATCAGGCTTGAGTCCATTGATAATCACTCTAGCACAGGTGGTCAGTCTGACCAAGGATACGGGTCTAAGG
ATGAACTTATAAAGGATGATGCAGAAATTCATGTGCCTGAAGAACAGGCAGCAAGAGAATTGATAACTAAAACAAAAATGCAAACAGAAG
AGGTGTGTGATGCCTCTGCTATTGTGGCAAAACATTCACAACCTAGTCCAGAGCCTCACAGTCCTACTGAACCTCCTGCATGGGGCAGCA
GTATTGTGAAAGTTCCGTCTGGTATATTTGATGTCAACAGCAGGAAAAGTAGCACTGGTAGTATATCAAATGTGCTGTTTTCTACTCAAG
ATCCAGTTGAAGATGCAGTCTTTGGCGAAGCTACTAATCTCAAGAAGAATGGTGATAGAGGAGAAAAAAGACAAAAGCATTTTCCTGAGA
GGAGTTGTAGTTTTAGTTCTGAAAGTCGAGCAGGAATGTTGCTTAAGAAGAGTAGTTTGGATTCGAATTCAAGTGAAATGGCTATCATGA
TGGGAGCAGATGCCAAGATTCTCACAGCAGCATTGACATGTCCTAAGACTTCTCTACTTCATATTGCAAGAACCCATAGCTTTGAGAATG
TTAGCTGTCACCTACCTGATAGTAGGACTTGTATGTCTGAAAGCACTTGGAATCCTGAGCACAGATCATCTCCGGTGCCAGAGATGCTTG
AGGAAAGCCAAGAACTCCTTGAGCCTGTGGTTGATGACGTACCTAAAACTACTGCAACAGTAGATACATATGAGAGTCTACTAAGTGATA
GTAACAGTAATCAGTCCAGAGACTTGAAAACAGTATCCAAAGATCTGAGGAATAAGAGAAGTAGTTTATATGGTATTGCTAAGGTGGTTC
AGAGGGAAGATGTTGAAACTGGACTAGATCCTTTGTCTCTTTTAGCCACTGAATGTACAGGAGGAAAAACTCCTGATTCTGAAGATAAGT
TGTTTTCTCCAGTTATTGCACGTAATCTGGCTGATGAAATAGAAAGCTATATGAACCTAAAAAGTCCCCTAGGTAGTAAATCTTCTAGTA
TGGAATTACACAGAGAGGAAAACAGAGAGTCTGGCATGACTACTGCATTTATTCATGCTCTAGAGAGGAGATCAAGCCTACCTTTAGATC
ATGGTTCACCAGCACAGGAAAATCCTGAAAGTGAAAAGAGCTCACCTGCAGTGTCCAGGTCTAAAACTTTTACTGGGCGTTTCAAGCAGC
AAACCCCCTCTCGAACTCATAAAGAACGTTCAACTTCTTTGTCAGCACTGGTGCGTTCTTCGCCACATGGCTCGTTGGGTTCTGTAGTAA
ATTCTTTGTCAGGGCTAAAGCTGGATAATATACTCTCAGGGCCCAAGATAGATGTCCTGAAATCTGGTATGAAACAAGCAGCGACAGTAG
CCAGTAAGATGTGGGTAGCTGTTGCGTCTGCCTACAGCTACTCAGATGATGAGGAAGAAACTAATAGAGACTACAGCTTCCCAGCTGGCC
TAGAAGACCATATTTTGGGGGAGAATATATCGCCTAACACAAGTATCTCAGGGTTGGTCCCCAGTGAACTTACCCAGAGCAACACAAGTC
TTGGCAGTAGCAGCAGTAGTGGAGATGTAGGAAAACTGCATTATCCAACAGGTGAAGTTCCATTTCCAAGAGGCATGAAAGGGCAAGACT
TTGAAAAATCAGATCATGGTTCTTCTCAAAATACCAGCATGTCTAGCATCTATCAGAATTGTGCAATGGAGGTTTTGATGTCCAGTTGTT
CACAGTGTAGAGCTTGTGGAGCTTTAGTTTATGATGAAGAAATTATGGCTGGATGGACAGCAGATGACTCAAATTTGAATACAGCTTGTC
CATTCTGTAAAAGCAACTTCTTGCCTCTTCTCAATATAGAATTCAAAGATTTGAGAGGTTCTGCAAGCTTTTTCCTGAAACCAAGTACCT
CTGGTGACAGTTTACAAAGTGGAAGCATTCCATTGGCAAATGAATCCTTGGAGCACAAACCTGTATCCAGTTTAGCAGAACCTGACTTGA
TCAACTTTATGGACTTCCCAAAACATAACCAGATCATAACTGAAGAAACAGGCTCTGCAGTTGAACCAAGGTCCCGTTTAATGGATTCTG
ACATGGATTATGAAAGGCCAAACGTAGAGACCATCAAGTGCGTTGTGGTGGGGGACAACGCCGTGGGTAAGACCAGGCTCATCTGTGCCC
GCGCTTGCAATGCCACCCTCACCCAGTACCAGCTGCTGGCCACGCATGTGCCCACAGTATGGGCCATCGACCAATATCGTGTGTGCCAGG
AGGTGCTGGAACGCTCCCGAGACGTGGTAGATGATGTCAGCGTCTCTCTGCGCCTCTGGGACACCTTTGGAGACCACCACAAAGACCGTC
GCTTTGCTTATGGGAGATCTGATGTGGTGGTTCTGTGCTTCTCCATTGCCAACCCCAATTCCCTCCACCATGTCAAGACCATGTGGTACC
CAGAAATCAAGCACTTCTGCCCCCGAGCACCTGTCATCTTGGTGGGCTGCCAGTTGGACCTGCGCTACGCTGACCTGGAGGCTGTCAACA
GGGCTAGGCGACCCTTGGCTAGGCCCATCAAACCTAATGAAATCCTGCCCCCAGAGAAGGGTCGGGAGGTGGCCAAGGAGCTGGGCATCC
CCTACTATGAGACCAGCGTGGTGGCCCAGTTCGGCATCAAGGACGTCTTTGACAACGCCATCCGAGCTGCACTCATCTCCCGCCGCCACC
TGCAGTTCTGGAAGTCCCACCTCCGCAATGTGCAGCGGCCTCTGCTGCAGGCACCCTTCCTACCCCCCAAGCCACCGCCCCCGATCATCG
TGGTGCCCGACCCTCCCTCCAGCAGCGAGGAGTGCCCCGCCCACCTCCTGGAGGACCCGCTCTGCGCGGACGTCATCCTGGTGCTGCAGG
AGCGGGTGCGCATCTTTGCCCACAAGATCTACCTCTCCACCTCTTCCTCCAAGTTCTATGACCTGTTCCTCATGGACCTGAGTGAGGGGG
AGCTGGGGGGCCCCTCGGAGCCAGGGGGCACCCACCCAGAGGACCACCAGGGCCACTCTGATCAACACCACCACCATCACCACCACCACC
ATGGGCGAGACTTCCTGCTCCGAGCAGCCAGCTTTGACGTGTGCGAGAGCGTGGATGAGGCTGGGGGCTCCGGTCCTGCTGGCCTCCGTG
CTTCCACCAGCGACGGGATCTTACGGGGCAACGGAACAGGGTACCTACCGGGCAGGGGTCGTGTGCTGTCTTCCTGGAGCCGAGCTTTTG
TGAGCATCCAGGAAGAGATGGCAGAAGATCCTCTCACCTACAAATCCCGGCTGATGGTGGTGGTGAAGATGGACAGTTCCATCCAGCCGG
GGCCCTTCCGGGCTGTCCTCAAGTACCTGTACACGGGGGAGCTAGATGAGAACGAGCGTGACCTCATGCACATTGCCCACATTGCTGAGC
TGCTCGAGGTCTTTGATCTGCGCATGATGGTGGCCAACATTCTCAACAATGAGGCCTTCATGAACCAGGAGATCACCAAGGCCTTCCACG
TCCGCCGGACCAACCGGGTTAAGGAGTGCTTGGCAAAAGGCACCTTCTCAGATGTGACCTTCATCCTGGATGATGGCACCATCAGCGCCC
ACAAGCCCCTGTTGATTTCCAGCTGTGACTGGATGGCTGCCATGTTTGGGGGGCCATTTGTGGAGAGCTCCACCCGGGAGGTGGTGTTTC
CCTACACAAGCAAGAGCTGCATGCGGGCCGTGCTGGAATACCTCTACACCGGCATGTTCACCTCCAGCCCCGACCTGGATGACATGAAGC
TCATCATTCTAGCCAACCGCCTCTGCCTGCCACACCTGGTTGCCCTCACAGAGCAGTACACAGTGACCGGGCTGATGGAAGCGACCCAGA
TGATGGTGGACATCGATGGGGACGTCCTTGTGTTCCTGGAACTGGCTCAGTTCCACTGTGCGTACCAGCTGGCCGACTGGTGTCTCCACC
ACATCTGCACCAACTACAACAACGTGTGCCGCAAGTTCCCCCGAGACATGAAGGCCATGTCCCCAGAAAACCAGGAGTATTTCGAGAAGC
ATCGGTGGCCACCTGTGTGGTACCTGAAGGAGGAAGATCATTACCAGCGGGCACGGAAGGAGCGTGAGAAGGAGGACTACCTCCACCTCA
AGCGGCAGCCCAAACGGCGTTGGCTCTTCTGGAACAGTCCATCCTCCCCGTCTTCCTCGGCAGCCTCCTCCTCATCCCCATCTTCCTCCT
CGGCTGTGGTCTGAGATGCTGCCACCCTCTTCTGACCCTGCTGCTGTTGTCCCCATCCGCCTTCACCCCTCTGCTCTTCCGCATCACCCC
ATCCACCTTACAGGGACCAGGGGGCCCACGTAACCAGGACCCAGAGGGTGGAGCTCTTCTTACCAGCCACCGTGGCTCAGCCAGAGAGGA
GCTGAGCCCTGTGGAGCAGAACGGGAACCACCTGCAGAGGTCCCCAGACCCAAAGCAGGACGGGAGACAACTGCTTGGAGGAGCGAAGAG
CCCTGGCATTTTATCTCTGGGTTTGAGAGCCCTAGAGTCAAAGGGAAAGCCTCCCAGCCTCCAGGGCTTCTCTGTGTGTCTTGGTTGCTG
CTCTGGCCAGGGAGGCAGCCCCACTCCCAGCAAGCAGAAGTGATCCTCGAGGGTCCTGCCCCTGTTGGCCATATCTTTCCACCGACGGAC
TTGAGTGTTGCATTTGTTTTGTGGGCATTTCCACACGAAGCCTACTCACACCCTCACTGGAGAAGTCAGGGTAGAAATTGAGCCTTCAGA
GCCCAACTCAAGGCTTCTACATCCTGGGGTGCAGCTGCAAAAGGCCAGACGTGGAAAGGCCTGTATCCTGCCAGTGTCCCTCCGTCCCAG
GGGGCTGTGCTAGCACAGACCTGAGAATGGGGACACAGGTCATTCAGAGCTCCAGGCCTGGAAGCAGTGCCTCTTGGTGCAACAAGAAAC
TTCTCCCTCACCCCCTCCTTTACCCTCAGATTTGGAGATGGTAACCAAAGGAAGCAGCTGGGACAGGTGGAGAAGGAAGTAGGAATGAGT
GCACGGCGACCCCGTGCTCCTCAGGGCCCTCCCCTGCCTCTGGGTGGCACTGCTTTTTATAGGGTGGGGCAAAATTAGCAAAAAACAAAA

>22263_22263_5_DENND4C-RHOBTB2_DENND4C_chr9_19357152_ENST00000434457_RHOBTB2_chr8_22861937_ENST00000519685_length(amino acids)=2435AA_BP=1697
MRRRRPLELVPRPALPSAPSPRIRCFLAPGRSRVGAALTEEQAAENTVAAMIEDKGPRVTDYFVVAGLTDTSTLLDQEINRLDTKSTGPK
APITDIAIIIKSAGETVPEGYTCVEATPSALQANLNYGSLKSPELFLCYKRGRDKPPLTDIGVLYEGKERLIPGCEVILATPYGRCANVN
NSSTTSQRIFITYRRAPPVRPQNSLAVTDICVIVTSKGETPPHTFCKVDKNLNCGMWGSSVFLCYKKSVPASNAIAYKAGLIFRYPEEDY
ESFPLSESDVPLFCLPMGATIECWDPETKYPLPVFSTFVLTGSSAKKVYGAAIQFYEPYSRELLSEKQLMHLGLLTPVERKMVSKSINTN
KCICLLSHWPFFEAFRKFLMFIYKLSVSGPHPLPIEKHISHFMQNIPFPSPQRPRILVQLSVHDALILSQPVSTPLPLSGANFSTLLMNL
GPENCATLLLFVLLESKILLHSLRPAVLTGVAEAVVAMIFPFQWQCPYIPLCPLSLAAVLSAPLPFIVGVDSRYFDLHDPPQDVVCIDLD
TNMLYVSDEKKNMNWKQLPKKPCKNLLSTLKKLYPQLSSVHQKTQEGSAIDMTPIEADFSWQKKMTQLEMEIQEAFLRFMASILKGYRTY
LRPITEAPSNKATAADSLFDRQGFLKSRDRAYAKFYTLLSKTQIFIRFIEECSFVSDKDTGLAFFDDCIEKLFPDKGTEKTDKVDFDSAE
DTRLIELDDSQKSEHTVFIMPPEPPPDDGKDLSPKYSYKYFPRLDLKLFDRPQELKLCFSRHPTGNSITKSPPLMAKRTKQEIKTAHKLA
KRCYTNPPQWAKCLFSHCYSLWFICLPAYVRVSHPKVRALQQAYDVLIKMRKTDVDPLDEVCYRVVMQLCGLWGHPVLAVRVLFEMKTAR
IKPNAITYGYYNKVVLESPWPSSTRSGIFLWTKVRNVVRGLAQFRQPLKKTVQRSQVSSISALQNVTGGSDGDTVSHGSVDSSNDANNGE
HTVFVRDLIRLESIDNHSSTGGQSDQGYGSKDELIKDDAEIHVPEEQAARELITKTKMQTEEVCDASAIVAKHSQPSPEPHSPTEPPAWG
SSIVKVPSGIFDVNSRKSSTGSISNVLFSTQDPVEDAVFGEATNLKKNGDRGEKRQKHFPERSCSFSSESRAGMLLKKSSLDSNSSEMAI
MMGADAKILTAALTCPKTSLLHIARTHSFENVSCHLPDSRTCMSESTWNPEHRSSPVPEMLEESQELLEPVVDDVPKTTATVDTYESLLS
DSNSNQSRDLKTVSKDLRNKRSSLYGIAKVVQREDVETGLDPLSLLATECTGGKTPDSEDKLFSPVIARNLADEIESYMNLKSPLGSKSS
SMELHREENRESGMTTAFIHALERRSSLPLDHGSPAQENPESEKSSPAVSRSKTFTGRFKQQTPSRTHKERSTSLSALVRSSPHGSLGSV
VNSLSGLKLDNILSGPKIDVLKSGMKQAATVASKMWVAVASAYSYSDDEEETNRDYSFPAGLEDHILGENISPNTSISGLVPSELTQSNT
SLGSSSSSGDVGKLHYPTGEVPFPRGMKGQDFEKSDHGSSQNTSMSSIYQNCAMEVLMSSCSQCRACGALVYDEEIMAGWTADDSNLNTA
CPFCKSNFLPLLNIEFKDLRGSASFFLKPSTSGDSLQSGSIPLANESLEHKPVSSLAEPDLINFMDFPKHNQIITEETGSAVEPRSRLMD
SDMDYERPNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDDVSVSLRLWDTFGDHHKD
RRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKELG
IPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQAPFLPPKPPPPIIVVPDPPSSSEECPAHLLEDPLCADVILVL
QERVRIFAHKIYLSTSSSKFYDLFLMDLSEGELGGPSEPGGTHPEDHQGHSDQHHHHHHHHHGRDFLLRAASFDVCESVDEAGGSGPAGL
RASTSDGILRGNGTGYLPGRGRVLSSWSRAFVSIQEEMAEDPLTYKSRLMVVVKMDSSIQPGPFRAVLKYLYTGELDENERDLMHIAHIA
ELLEVFDLRMMVANILNNEAFMNQEITKAFHVRRTNRVKECLAKGTFSDVTFILDDGTISAHKPLLISSCDWMAAMFGGPFVESSTREVV
FPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIILANRLCLPHLVALTEQYTVTGLMEATQMMVDIDGDVLVFLELAQFHCAYQLADWCL
HHICTNYNNVCRKFPRDMKAMSPENQEYFEKHRWPPVWYLKEEDHYQRARKEREKEDYLHLKRQPKRRWLFWNSPSSPSSSAASSSSPSS

--------------------------------------------------------------
>22263_22263_6_DENND4C-RHOBTB2_DENND4C_chr9_19357152_ENST00000434457_RHOBTB2_chr8_22861937_ENST00000522948_length(transcript)=10297nt_BP=5380nt
GGAGGAAAGGGAGAGGGAGGGGGAAAAGAAAGTGCTGTTTTGTGGAAAGGGGCGGAAGGCGGGGGAGAAAAAGGGAACAGAAACATGGCG
GTCAGGTCTTGGGACGGCTGCGCCGCGGGCAGCTCCTAGGCGACGCGCCGCCCGCACTGTCCGACGGCTCACAGCGCGGAGGCACCCGCG
CGGGCCAGCGCTCCGGCCATCGCCCCTGGCTGTAGGCGGCGCCCCTCGGAGACCCTGCCCGCGAGGCGGCGCAGGCGCAGACCGGACTGA
GGCGGCGGCGGCCGCTGGAGCTAGTCCCCCGCCCTGCCCTGCCGAGCGCGCCCAGTCCGCGAATCCGGTGCTTTCTTGCCCCAGGAAGAA
GCCGTGTCGGGGCTGCGCTGACAGAGGAGCAGGCAGCAGAAAATACAGTAGCAGCCATGATAGAAGACAAAGGACCAAGAGTGACAGACT
ACTTTGTCGTAGCTGGTCTCACTGACACATCTACTCTTTTGGATCAAGAAATAAATCGTTTAGATACTAAGTCAACTGGACCTAAAGCTC
CAATTACAGACATTGCCATTATTATCAAATCAGCTGGAGAAACAGTACCTGAAGGTTACACCTGTGTAGAAGCCACTCCATCAGCTCTCC
AAGCAAACTTGAACTATGGAAGTCTGAAAAGCCCAGAACTTTTCCTCTGTTATAAGAGAGGGAGAGATAAACCACCGCTTACAGATATTG
GAGTTCTATATGAAGGGAAAGAACGGCTTATTCCAGGATGTGAAGTGATCCTAGCCACACCCTATGGTCGCTGTGCCAATGTCAACAATA
GTTCAACTACTTCACAAAGAATCTTTATCACTTATCGAAGGGCTCCTCCAGTTCGACCCCAGAATTCCTTGGCTGTAACTGATATCTGTG
TTATTGTAACCAGTAAAGGAGAAACTCCTCCTCATACCTTCTGCAAAGTTGACAAAAACTTAAATTGTGGAATGTGGGGTTCCAGCGTGT
TTCTGTGTTATAAGAAGTCTGTACCTGCTTCAAATGCAATAGCATATAAGGCTGGTTTAATTTTTAGATATCCAGAAGAGGACTATGAGT
CATTTCCACTCTCAGAATCAGATGTACCTCTTTTCTGCCTTCCTATGGGAGCTACTATTGAGTGCTGGGATCCTGAAACCAAATATCCAC
TTCCAGTTTTTTCAACTTTTGTCTTGACAGGTTCTTCAGCCAAAAAGGTATATGGAGCTGCCATTCAGTTTTATGAACCTTACTCTCGGG
AACTTCTATCAGAGAAACAGCTTATGCACCTGGGCTTGTTGACGCCTGTGGAGAGAAAAATGGTCTCCAAATCCATCAATACAAACAAAT
GCATTTGTTTACTCTCACACTGGCCTTTTTTTGAAGCTTTTAGGAAATTTCTTATGTTTATCTACAAACTTTCTGTGTCTGGACCACATC
CTCTTCCCATTGAAAAGCACATTTCACATTTTATGCAAAACATCCCTTTTCCTTCACCACAAAGACCGAGAATCCTTGTCCAGCTGTCAG
TCCATGATGCATTAATATTATCACAGCCAGTTTCTACACCTTTACCACTAAGTGGAGCCAACTTTAGCACCTTGCTAATGAATCTGGGTC
CTGAGAATTGTGCAACACTGCTGCTCTTTGTTTTACTTGAGAGTAAAATTCTGCTGCATTCTCTTAGGCCAGCTGTCTTGACTGGGGTAG
CTGAAGCTGTTGTAGCTATGATCTTTCCATTTCAGTGGCAATGCCCATATATTCCCCTTTGTCCTCTTTCACTGGCTGCAGTGCTTAGTG
CACCTTTACCATTTATAGTTGGAGTTGACTCAAGGTATTTTGATCTTCATGACCCACCACAAGATGTTGTTTGCATTGACTTGGATACGA
ACATGTTATATGTATCAGATGAAAAGAAGAACATGAACTGGAAGCAACTTCCCAAAAAGCCGTGCAAAAATCTACTTAGCACCTTAAAGA
AATTGTATCCCCAGCTGTCTTCAGTTCACCAAAAAACTCAAGAAGGCTCAGCGATTGACATGACTCCAATTGAAGCAGATTTCTCCTGGC
AAAAGAAGATGACACAGCTTGAGATGGAAATTCAAGAGGCATTTTTGCGCTTTATGGCGTCTATTTTAAAAGGATATAGAACATATCTCA
GACCAATCACAGAGGCTCCTTCAAATAAAGCCACAGCTGCTGATTCATTGTTTGACCGACAGGGATTTTTAAAAAGTCGAGATCGTGCCT
ATGCAAAATTCTATACCCTTTTATCCAAAACACAGATTTTTATTCGTTTCATTGAAGAATGCAGTTTTGTAAGTGATAAAGATACTGGAT
TAGCATTTTTTGATGACTGCATAGAAAAGTTGTTTCCTGATAAAGGCACAGAGAAAACAGATAAGGTTGATTTTGATTCAGCAGAAGATA
CCAGATTGATAGAACTAGATGATTCACAGAAAAGTGAGCATACTGTATTTATAATGCCGCCAGAGCCACCTCCTGATGATGGAAAGGACC
TGTCACCAAAGTACAGTTACAAATACTTTCCAAGACTGGACCTTAAGCTTTTTGACAGACCGCAGGAGTTGAAACTTTGTTTTAGTAGAC
ACCCTACTGGGAATAGCATTACAAAGAGTCCACCTCTCATGGCTAAGAGAACTAAACAGGAAATAAAAACAGCTCATAAATTGGCGAAGA
GATGTTATACAAATCCACCACAGTGGGCCAAGTGTCTGTTTAGTCATTGTTACAGTTTATGGTTTATTTGTCTTCCGGCCTATGTTAGAG
TTTCTCATCCTAAAGTCAGAGCACTTCAGCAGGCATATGATGTACTTATTAAGATGAGGAAAACAGATGTGGATCCCTTAGATGAGGTGT
GCTATCGAGTAGTGATGCAGCTTTGTGGACTTTGGGGTCATCCTGTTTTAGCAGTGAGAGTCTTATTTGAAATGAAAACTGCTAGGATAA
AGCCTAATGCTATTACTTATGGTTATTATAATAAGGTAGTCTTGGAGAGCCCGTGGCCTAGCAGTACCCGCAGTGGTATTTTCTTATGGA
CGAAGGTACGGAATGTGGTACGTGGCTTGGCACAGTTTAGGCAGCCGCTTAAAAAGACTGTGCAAAGGTCACAGGTCTCCTCAATATCAG
CTCTTCAAAATGTCACAGGTGGAAGTGATGGGGACACGGTGAGCCACGGTAGTGTGGATAGTTCTAATGATGCTAACAATGGGGAGCACA
CAGTCTTCGTCAGAGATTTAATCAGGCTTGAGTCCATTGATAATCACTCTAGCACAGGTGGTCAGTCTGACCAAGGATACGGGTCTAAGG
ATGAACTTATAAAGGATGATGCAGAAATTCATGTGCCTGAAGAACAGGCAGCAAGAGAATTGATAACTAAAACAAAAATGCAAACAGAAG
AGGTGTGTGATGCCTCTGCTATTGTGGCAAAACATTCACAACCTAGTCCAGAGCCTCACAGTCCTACTGAACCTCCTGCATGGGGCAGCA
GTATTGTGAAAGTTCCGTCTGGTATATTTGATGTCAACAGCAGGAAAAGTAGCACTGGTAGTATATCAAATGTGCTGTTTTCTACTCAAG
ATCCAGTTGAAGATGCAGTCTTTGGCGAAGCTACTAATCTCAAGAAGAATGGTGATAGAGGAGAAAAAAGACAAAAGCATTTTCCTGAGA
GGAGTTGTAGTTTTAGTTCTGAAAGTCGAGCAGGAATGTTGCTTAAGAAGAGTAGTTTGGATTCGAATTCAAGTGAAATGGCTATCATGA
TGGGAGCAGATGCCAAGATTCTCACAGCAGCATTGACATGTCCTAAGACTTCTCTACTTCATATTGCAAGAACCCATAGCTTTGAGAATG
TTAGCTGTCACCTACCTGATAGTAGGACTTGTATGTCTGAAAGCACTTGGAATCCTGAGCACAGATCATCTCCGGTGCCAGAGATGCTTG
AGGAAAGCCAAGAACTCCTTGAGCCTGTGGTTGATGACGTACCTAAAACTACTGCAACAGTAGATACATATGAGAGTCTACTAAGTGATA
GTAACAGTAATCAGTCCAGAGACTTGAAAACAGTATCCAAAGATCTGAGGAATAAGAGAAGTAGTTTATATGGTATTGCTAAGGTGGTTC
AGAGGGAAGATGTTGAAACTGGACTAGATCCTTTGTCTCTTTTAGCCACTGAATGTACAGGAGGAAAAACTCCTGATTCTGAAGATAAGT
TGTTTTCTCCAGTTATTGCACGTAATCTGGCTGATGAAATAGAAAGCTATATGAACCTAAAAAGTCCCCTAGGTAGTAAATCTTCTAGTA
TGGAATTACACAGAGAGGAAAACAGAGAGTCTGGCATGACTACTGCATTTATTCATGCTCTAGAGAGGAGATCAAGCCTACCTTTAGATC
ATGGTTCACCAGCACAGGAAAATCCTGAAAGTGAAAAGAGCTCACCTGCAGTGTCCAGGTCTAAAACTTTTACTGGGCGTTTCAAGCAGC
AAACCCCCTCTCGAACTCATAAAGAACGTTCAACTTCTTTGTCAGCACTGGTGCGTTCTTCGCCACATGGCTCGTTGGGTTCTGTAGTAA
ATTCTTTGTCAGGGCTAAAGCTGGATAATATACTCTCAGGGCCCAAGATAGATGTCCTGAAATCTGGTATGAAACAAGCAGCGACAGTAG
CCAGTAAGATGTGGGTAGCTGTTGCGTCTGCCTACAGCTACTCAGATGATGAGGAAGAAACTAATAGAGACTACAGCTTCCCAGCTGGCC
TAGAAGACCATATTTTGGGGGAGAATATATCGCCTAACACAAGTATCTCAGGGTTGGTCCCCAGTGAACTTACCCAGAGCAACACAAGTC
TTGGCAGTAGCAGCAGTAGTGGAGATGTAGGAAAACTGCATTATCCAACAGGTGAAGTTCCATTTCCAAGAGGCATGAAAGGGCAAGACT
TTGAAAAATCAGATCATGGTTCTTCTCAAAATACCAGCATGTCTAGCATCTATCAGAATTGTGCAATGGAGGTTTTGATGTCCAGTTGTT
CACAGTGTAGAGCTTGTGGAGCTTTAGTTTATGATGAAGAAATTATGGCTGGATGGACAGCAGATGACTCAAATTTGAATACAGCTTGTC
CATTCTGTAAAAGCAACTTCTTGCCTCTTCTCAATATAGAATTCAAAGATTTGAGAGGTTCTGCAAGCTTTTTCCTGAAACCAAGTACCT
CTGGTGACAGTTTACAAAGTGGAAGCATTCCATTGGCAAATGAATCCTTGGAGCACAAACCTGTATCCAGTTTAGCAGAACCTGACTTGA
TCAACTTTATGGACTTCCCAAAACATAACCAGATCATAACTGAAGAAACAGGCTCTGCAGTTGAACCAAGGTCCCGTTTAATGGATTCTG
ACATGGATTATGAAAGGCCAAACGTAGAGACCATCAAGTGCGTTGTGGTGGGGGACAACGCCGTGGGTAAGACCAGGCTCATCTGTGCCC
GCGCTTGCAATGCCACCCTCACCCAGTACCAGCTGCTGGCCACGCATGTGCCCACAGTATGGGCCATCGACCAATATCGTGTGTGCCAGG
AGGTGCTGGAACGCTCCCGAGACGTGGTAGATGATGTCAGCGTCTCTCTGCGCCTCTGGGACACCTTTGGAGACCACCACAAAGACCGTC
GCTTTGCTTATGGGAGATCTGATGTGGTGGTTCTGTGCTTCTCCATTGCCAACCCCAATTCCCTCCACCATGTCAAGACCATGTGGTACC
CAGAAATCAAGCACTTCTGCCCCCGAGCACCTGTCATCTTGGTGGGCTGCCAGTTGGACCTGCGCTACGCTGACCTGGAGGCTGTCAACA
GGGCTAGGCGACCCTTGGCTAGGCCCATCAAACCTAATGAAATCCTGCCCCCAGAGAAGGGTCGGGAGGTGGCCAAGGAGCTGGGCATCC
CCTACTATGAGACCAGCGTGGTGGCCCAGTTCGGCATCAAGGACGTCTTTGACAACGCCATCCGAGCTGCACTCATCTCCCGCCGCCACC
TGCAGTTCTGGAAGTCCCACCTCCGCAATGTGCAGCGGCCTCTGCTGCAGGCACCCTTCCTACCCCCCAAGCCACCGCCCCCGATCATCG
TGGTGCCCGACCCTCCCTCCAGCAGCGAGGAGTGCCCCGCCCACCTCCTGGAGGACCCGCTCTGCGCGGACGTCATCCTGGTGCTGCAGG
AGCGGGTGCGCATCTTTGCCCACAAGATCTACCTCTCCACCTCTTCCTCCAAGTTCTATGACCTGTTCCTCATGGACCTGAGTGAGGGGG
AGCTGGGGGGCCCCTCGGAGCCAGGGGGCACCCACCCAGAGGACCACCAGGGCCACTCTGATCAACACCACCACCATCACCACCACCACC
ATGGGCGAGACTTCCTGCTCCGAGCAGCCAGCTTTGACGTGTGCGAGAGCGTGGATGAGGCTGGGGGCTCCGGTCCTGCTGGCCTCCGTG
CTTCCACCAGCGACGGGATCTTACGGGGCAACGGAACAGGGTACCTACCGGGCAGGGGTCGTGTGCTGTCTTCCTGGAGCCGAGCTTTTG
TGAGCATCCAGGAAGAGATGGCAGAAGATCCTCTCACCTACAAATCCCGGCTGATGGTGGTGGTGAAGATGGACAGTTCCATCCAGCCGG
GGCCCTTCCGGGCTGTCCTCAAGTACCTGTACACGGGGGAGCTAGATGAGAACGAGCGTGACCTCATGCACATTGCCCACATTGCTGAGC
TGCTCGAGGTCTTTGATCTGCGCATGATGGTGGCCAACATTCTCAACAATGAGGCCTTCATGAACCAGGAGATCACCAAGGCCTTCCACG
TCCGCCGGACCAACCGGGTTAAGGAGTGCTTGGCAAAAGGCACCTTCTCAGATGTGACCTTCATCCTGGATGATGGCACCATCAGCGCCC
ACAAGCCCCTGTTGATTTCCAGCTGTGACTGGATGGCTGCCATGTTTGGGGGGCCATTTGTGGAGAGCTCCACCCGGGAGGTGGTGTTTC
CCTACACAAGCAAGAGCTGCATGCGGGCCGTGCTGGAATACCTCTACACCGGCATGTTCACCTCCAGCCCCGACCTGGATGACATGAAGC
TCATCATTCTAGCCAACCGCCTCTGCCTGCCACACCTGGTTGCCCTCACAGAGCAGTACACAGTGACCGGGCTGATGGAAGCGACCCAGA
TGATGGTGGACATCGATGGGGACGTCCTTGTGTTCCTGGAACTGGCTCAGTTCCACTGTGCGTACCAGCTGGCCGACTGGTGTCTCCACC
ACATCTGCACCAACTACAACAACGTGTGCCGCAAGTTCCCCCGAGACATGAAGGCCATGTCCCCAGAAAACCAGGAGTATTTCGAGAAGC
ATCGGTGGCCACCTGTGTGGTACCTGAAGGAGGAAGATCATTACCAGCGGGCACGGAAGGAGCGTGAGAAGGAGGACTACCTCCACCTCA
AGCGGCAGCCCAAACGGCGTTGGCTCTTCTGGAACAGTCCATCCTCCCCGTCTTCCTCGGCAGCCTCCTCCTCATCCCCATCTTCCTCCT
CGGCTGTGGTCTGAGATGCTGCCACCCTCTTCTGACCCTGCTGCTGTTGTCCCCATCCGCCTTCACCCCTCTGCTCTTCCGCATCACCCC
ATCCACCTTACAGGGACCAGGGGGCCCACGTAACCAGGACCCAGAGGGTGGAGCTCTTCTTACCAGCCACCGTGGCTCAGCCAGAGAGGA
GCTGAGCCCTGTGGAGCAGAACGGGAACCACCTGCAGAGGTCCCCAGACCCAAAGCAGGACGGGAGACAACTGCTTGGAGGAGCGAAGAG
CCCTGGCATTTTATCTCTGGGTTTGAGAGCCCTAGAGTCAAAGGGAAAGCCTCCCAGCCTCCAGGGCTTCTCTGTGTGTCTTGGTTGCTG
CTCTGGCCAGGGAGGCAGCCCCACTCCCAGCAAGCAGAAGTGATCCTCGAGGGTCCTGCCCCTGTTGGCCATATCTTTCCACCGACGGAC
TTGAGTGTTGCATTTGTTTTGTGGGCATTTCCACACGAAGCCTACTCACACCCTCACTGGAGAAGTCAGGGTAGAAATTGAGCCTTCAGA
GCCCAACTCAAGGCTTCTACATCCTGGGGTGCAGCTGCAAAAGGCCAGACGTGGAAAGGCCTGTATCCTGCCAGTGTCCCTCCGTCCCAG
GGGGCTGTGCTAGCACAGACCTGAGAATGGGGACACAGGTCATTCAGAGCTCCAGGCCTGGAAGCAGTGCCTCTTGGTGCAACAAGAAAC
TTCTCCCTCACCCCCTCCTTTACCCTCAGATTTGGAGATGGTAACCAAAGGAAGCAGCTGGGACAGGTGGAGAAGGAAGTAGGAATGAGT
GCACGGCGACCCCGTGCTCCTCAGGGCCCTCCCCTGCCTCTGGGTGGCACTGCTTTTTATAGGGTGGGGCAAAATTAGCAAAAAACAAAA
ACCAATGACAACCAAACTGAAACCGAAACGAAAAATCAACAAACACTCTGTCCTCTATCCCTCCAAAGAATGAAAATCAGAAAAAGCCCC
TGCCTAGCTCACATTTCTATAAACAGAGGCCCCCATGATGAGGAGGTGAAGATTTAGGTTGCAGAATCGACTCCAATGCCTTTCAGGAAA
GGACTCGGCACTTCTCTGACTGCGGAGGCCCTGACCCTGCCAGCTGGCTCCGAGGGCAACACAGGGGCCTGGCCTCTAGAGGGCTGGTGA
TTGAGGGGCCCGGGCTGGCGGCAAAGAGGGGTTTGGTCTCGGGGCTTAAATGGCACCAGACTCTTGCTTTTGCCCATCTGGAGACTGCAG
GCTCCCTTCCTTACCCTCAGAGAGTGCTTATGGTGGGTGTTTTTGCGGGGCTGCAATAGGGGCCAAAAGTCAGGGAAAGGGGCACTGACC
TGTAGTGAAAGGCCACAGGACACAGCCTTATTACTGCTGGGGTGGGATAAGGGGAAGGAGAAGAGGGAGAATGGAGCAGGAGGAAAAGCA
GAGTTGGTCTAGAGAGGAGGAGGGCGGGGCTGGAGGAATGTGGGGGATTGAAACTAGCTCCCAGCCCCCATGGGGCAGCAGCTGGGCCAC
AATTGCCCCTTTCCGTTTTCTAACCCCGACTCAGATTTCACCACCCACACTCTTTTTAGGTGTAAAAGATGGAGTCCCACGGAGGAGGGG
CAGAGCCAGGAGGCAGTGGGGCTGTGGGCTCAGAGCTCAGGAGTCGCCTTACCTGAGAGAGATGTTCTAGCTGAGAGGGCCTGGCCCTGG
GGTGGGCTCCAGGAAAACGCTGGTTAGGCCTGGGATTGAGCTAACCTGAAACAAAGGTAGCAGGCAGGACCTAATGACCAGAGGTTAAAT
CCTCATCAAGAGAGACCAGGCGGCTGGAGGACAAGCGGCTCTAACCCTGGGGGCGGCCATGTTGTCCAGGCCCAGGCCCCTCCAGGACTG
TGGCTGCCTCCCCTCCACGGCCTCCAGGGCGGCTGGCTGGAAAGCCACGCGTATGCTGCCCTCTACAGGCTGCTCGGCCTCCCTGCAGCT
CAGCGCAGCCCAGGGCTCCAAGTGAGGCCCAGAAGCCCATGGGCAGGGCTGGGGGGACGAAGGGGGAACCCGGAGCACCTCCACTTCTAG
GGAAGATGGACAGCGTGGGGGCACACCTGGGCCTCCCGGAAGCTGTGGACGAAAGGGAGAGCGGGTCCTCCAGGGCAAGGGGAACGGGAA
ATAGGTCTCCTAGGTGCCTGAAGCGCTGAGCAACCTGGGTACCCTGGTGGGGATGCAGGGAAGGCCGGGGCAGAGAAAGTGAAGGTCGAC
CCAGGGCTGTAGGAAGCCATAGGAGAGTGACCACGGGATTCCCTGAGAAACAGGGCCGGCCCCCCAACTTCAGGGACCCACCGCCCATTC
CCCGAGAGCTGTCGGAACCAGATGCAACCCGGCAGCCCAGAGAACTCTCCTGGGAGGCTGTGGGTGAGCCAGGCCAACATTGGTGTCCCT
GTCCCCAGAGGGAGGAGCAGGCAGGAGAGAGAGGGGAAGGAGGTATGAATCCCAGTCCCCAGGAACCTAGCTCTTTAAACTCTGGGGAGT
CGGATTCAGGAAACACCCCCAGGAGGCCAAGCCTGAAAACAGAGGGGAGGGAGGAAGGAAGGAGTCCCAGCAGGAGCACAGCCCTGGTTT
CCTGTCACTCAGAGCTGATTCACAGGAGGAGGGGAGGTTGGGGGGCGGGAGACAAAAACCACACCTCTTTTTATATAAGGTTTCATATTT

>22263_22263_6_DENND4C-RHOBTB2_DENND4C_chr9_19357152_ENST00000434457_RHOBTB2_chr8_22861937_ENST00000522948_length(amino acids)=2435AA_BP=1697
MRRRRPLELVPRPALPSAPSPRIRCFLAPGRSRVGAALTEEQAAENTVAAMIEDKGPRVTDYFVVAGLTDTSTLLDQEINRLDTKSTGPK
APITDIAIIIKSAGETVPEGYTCVEATPSALQANLNYGSLKSPELFLCYKRGRDKPPLTDIGVLYEGKERLIPGCEVILATPYGRCANVN
NSSTTSQRIFITYRRAPPVRPQNSLAVTDICVIVTSKGETPPHTFCKVDKNLNCGMWGSSVFLCYKKSVPASNAIAYKAGLIFRYPEEDY
ESFPLSESDVPLFCLPMGATIECWDPETKYPLPVFSTFVLTGSSAKKVYGAAIQFYEPYSRELLSEKQLMHLGLLTPVERKMVSKSINTN
KCICLLSHWPFFEAFRKFLMFIYKLSVSGPHPLPIEKHISHFMQNIPFPSPQRPRILVQLSVHDALILSQPVSTPLPLSGANFSTLLMNL
GPENCATLLLFVLLESKILLHSLRPAVLTGVAEAVVAMIFPFQWQCPYIPLCPLSLAAVLSAPLPFIVGVDSRYFDLHDPPQDVVCIDLD
TNMLYVSDEKKNMNWKQLPKKPCKNLLSTLKKLYPQLSSVHQKTQEGSAIDMTPIEADFSWQKKMTQLEMEIQEAFLRFMASILKGYRTY
LRPITEAPSNKATAADSLFDRQGFLKSRDRAYAKFYTLLSKTQIFIRFIEECSFVSDKDTGLAFFDDCIEKLFPDKGTEKTDKVDFDSAE
DTRLIELDDSQKSEHTVFIMPPEPPPDDGKDLSPKYSYKYFPRLDLKLFDRPQELKLCFSRHPTGNSITKSPPLMAKRTKQEIKTAHKLA
KRCYTNPPQWAKCLFSHCYSLWFICLPAYVRVSHPKVRALQQAYDVLIKMRKTDVDPLDEVCYRVVMQLCGLWGHPVLAVRVLFEMKTAR
IKPNAITYGYYNKVVLESPWPSSTRSGIFLWTKVRNVVRGLAQFRQPLKKTVQRSQVSSISALQNVTGGSDGDTVSHGSVDSSNDANNGE
HTVFVRDLIRLESIDNHSSTGGQSDQGYGSKDELIKDDAEIHVPEEQAARELITKTKMQTEEVCDASAIVAKHSQPSPEPHSPTEPPAWG
SSIVKVPSGIFDVNSRKSSTGSISNVLFSTQDPVEDAVFGEATNLKKNGDRGEKRQKHFPERSCSFSSESRAGMLLKKSSLDSNSSEMAI
MMGADAKILTAALTCPKTSLLHIARTHSFENVSCHLPDSRTCMSESTWNPEHRSSPVPEMLEESQELLEPVVDDVPKTTATVDTYESLLS
DSNSNQSRDLKTVSKDLRNKRSSLYGIAKVVQREDVETGLDPLSLLATECTGGKTPDSEDKLFSPVIARNLADEIESYMNLKSPLGSKSS
SMELHREENRESGMTTAFIHALERRSSLPLDHGSPAQENPESEKSSPAVSRSKTFTGRFKQQTPSRTHKERSTSLSALVRSSPHGSLGSV
VNSLSGLKLDNILSGPKIDVLKSGMKQAATVASKMWVAVASAYSYSDDEEETNRDYSFPAGLEDHILGENISPNTSISGLVPSELTQSNT
SLGSSSSSGDVGKLHYPTGEVPFPRGMKGQDFEKSDHGSSQNTSMSSIYQNCAMEVLMSSCSQCRACGALVYDEEIMAGWTADDSNLNTA
CPFCKSNFLPLLNIEFKDLRGSASFFLKPSTSGDSLQSGSIPLANESLEHKPVSSLAEPDLINFMDFPKHNQIITEETGSAVEPRSRLMD
SDMDYERPNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDDVSVSLRLWDTFGDHHKD
RRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKELG
IPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQAPFLPPKPPPPIIVVPDPPSSSEECPAHLLEDPLCADVILVL
QERVRIFAHKIYLSTSSSKFYDLFLMDLSEGELGGPSEPGGTHPEDHQGHSDQHHHHHHHHHGRDFLLRAASFDVCESVDEAGGSGPAGL
RASTSDGILRGNGTGYLPGRGRVLSSWSRAFVSIQEEMAEDPLTYKSRLMVVVKMDSSIQPGPFRAVLKYLYTGELDENERDLMHIAHIA
ELLEVFDLRMMVANILNNEAFMNQEITKAFHVRRTNRVKECLAKGTFSDVTFILDDGTISAHKPLLISSCDWMAAMFGGPFVESSTREVV
FPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIILANRLCLPHLVALTEQYTVTGLMEATQMMVDIDGDVLVFLELAQFHCAYQLADWCL
HHICTNYNNVCRKFPRDMKAMSPENQEYFEKHRWPPVWYLKEEDHYQRARKEREKEDYLHLKRQPKRRWLFWNSPSSPSSSAASSSSPSS

--------------------------------------------------------------
>22263_22263_7_DENND4C-RHOBTB2_DENND4C_chr9_19357152_ENST00000434457_RHOBTB2_chr8_22861938_ENST00000519685_length(transcript)=8546nt_BP=5380nt
GGAGGAAAGGGAGAGGGAGGGGGAAAAGAAAGTGCTGTTTTGTGGAAAGGGGCGGAAGGCGGGGGAGAAAAAGGGAACAGAAACATGGCG
GTCAGGTCTTGGGACGGCTGCGCCGCGGGCAGCTCCTAGGCGACGCGCCGCCCGCACTGTCCGACGGCTCACAGCGCGGAGGCACCCGCG
CGGGCCAGCGCTCCGGCCATCGCCCCTGGCTGTAGGCGGCGCCCCTCGGAGACCCTGCCCGCGAGGCGGCGCAGGCGCAGACCGGACTGA
GGCGGCGGCGGCCGCTGGAGCTAGTCCCCCGCCCTGCCCTGCCGAGCGCGCCCAGTCCGCGAATCCGGTGCTTTCTTGCCCCAGGAAGAA
GCCGTGTCGGGGCTGCGCTGACAGAGGAGCAGGCAGCAGAAAATACAGTAGCAGCCATGATAGAAGACAAAGGACCAAGAGTGACAGACT
ACTTTGTCGTAGCTGGTCTCACTGACACATCTACTCTTTTGGATCAAGAAATAAATCGTTTAGATACTAAGTCAACTGGACCTAAAGCTC
CAATTACAGACATTGCCATTATTATCAAATCAGCTGGAGAAACAGTACCTGAAGGTTACACCTGTGTAGAAGCCACTCCATCAGCTCTCC
AAGCAAACTTGAACTATGGAAGTCTGAAAAGCCCAGAACTTTTCCTCTGTTATAAGAGAGGGAGAGATAAACCACCGCTTACAGATATTG
GAGTTCTATATGAAGGGAAAGAACGGCTTATTCCAGGATGTGAAGTGATCCTAGCCACACCCTATGGTCGCTGTGCCAATGTCAACAATA
GTTCAACTACTTCACAAAGAATCTTTATCACTTATCGAAGGGCTCCTCCAGTTCGACCCCAGAATTCCTTGGCTGTAACTGATATCTGTG
TTATTGTAACCAGTAAAGGAGAAACTCCTCCTCATACCTTCTGCAAAGTTGACAAAAACTTAAATTGTGGAATGTGGGGTTCCAGCGTGT
TTCTGTGTTATAAGAAGTCTGTACCTGCTTCAAATGCAATAGCATATAAGGCTGGTTTAATTTTTAGATATCCAGAAGAGGACTATGAGT
CATTTCCACTCTCAGAATCAGATGTACCTCTTTTCTGCCTTCCTATGGGAGCTACTATTGAGTGCTGGGATCCTGAAACCAAATATCCAC
TTCCAGTTTTTTCAACTTTTGTCTTGACAGGTTCTTCAGCCAAAAAGGTATATGGAGCTGCCATTCAGTTTTATGAACCTTACTCTCGGG
AACTTCTATCAGAGAAACAGCTTATGCACCTGGGCTTGTTGACGCCTGTGGAGAGAAAAATGGTCTCCAAATCCATCAATACAAACAAAT
GCATTTGTTTACTCTCACACTGGCCTTTTTTTGAAGCTTTTAGGAAATTTCTTATGTTTATCTACAAACTTTCTGTGTCTGGACCACATC
CTCTTCCCATTGAAAAGCACATTTCACATTTTATGCAAAACATCCCTTTTCCTTCACCACAAAGACCGAGAATCCTTGTCCAGCTGTCAG
TCCATGATGCATTAATATTATCACAGCCAGTTTCTACACCTTTACCACTAAGTGGAGCCAACTTTAGCACCTTGCTAATGAATCTGGGTC
CTGAGAATTGTGCAACACTGCTGCTCTTTGTTTTACTTGAGAGTAAAATTCTGCTGCATTCTCTTAGGCCAGCTGTCTTGACTGGGGTAG
CTGAAGCTGTTGTAGCTATGATCTTTCCATTTCAGTGGCAATGCCCATATATTCCCCTTTGTCCTCTTTCACTGGCTGCAGTGCTTAGTG
CACCTTTACCATTTATAGTTGGAGTTGACTCAAGGTATTTTGATCTTCATGACCCACCACAAGATGTTGTTTGCATTGACTTGGATACGA
ACATGTTATATGTATCAGATGAAAAGAAGAACATGAACTGGAAGCAACTTCCCAAAAAGCCGTGCAAAAATCTACTTAGCACCTTAAAGA
AATTGTATCCCCAGCTGTCTTCAGTTCACCAAAAAACTCAAGAAGGCTCAGCGATTGACATGACTCCAATTGAAGCAGATTTCTCCTGGC
AAAAGAAGATGACACAGCTTGAGATGGAAATTCAAGAGGCATTTTTGCGCTTTATGGCGTCTATTTTAAAAGGATATAGAACATATCTCA
GACCAATCACAGAGGCTCCTTCAAATAAAGCCACAGCTGCTGATTCATTGTTTGACCGACAGGGATTTTTAAAAAGTCGAGATCGTGCCT
ATGCAAAATTCTATACCCTTTTATCCAAAACACAGATTTTTATTCGTTTCATTGAAGAATGCAGTTTTGTAAGTGATAAAGATACTGGAT
TAGCATTTTTTGATGACTGCATAGAAAAGTTGTTTCCTGATAAAGGCACAGAGAAAACAGATAAGGTTGATTTTGATTCAGCAGAAGATA
CCAGATTGATAGAACTAGATGATTCACAGAAAAGTGAGCATACTGTATTTATAATGCCGCCAGAGCCACCTCCTGATGATGGAAAGGACC
TGTCACCAAAGTACAGTTACAAATACTTTCCAAGACTGGACCTTAAGCTTTTTGACAGACCGCAGGAGTTGAAACTTTGTTTTAGTAGAC
ACCCTACTGGGAATAGCATTACAAAGAGTCCACCTCTCATGGCTAAGAGAACTAAACAGGAAATAAAAACAGCTCATAAATTGGCGAAGA
GATGTTATACAAATCCACCACAGTGGGCCAAGTGTCTGTTTAGTCATTGTTACAGTTTATGGTTTATTTGTCTTCCGGCCTATGTTAGAG
TTTCTCATCCTAAAGTCAGAGCACTTCAGCAGGCATATGATGTACTTATTAAGATGAGGAAAACAGATGTGGATCCCTTAGATGAGGTGT
GCTATCGAGTAGTGATGCAGCTTTGTGGACTTTGGGGTCATCCTGTTTTAGCAGTGAGAGTCTTATTTGAAATGAAAACTGCTAGGATAA
AGCCTAATGCTATTACTTATGGTTATTATAATAAGGTAGTCTTGGAGAGCCCGTGGCCTAGCAGTACCCGCAGTGGTATTTTCTTATGGA
CGAAGGTACGGAATGTGGTACGTGGCTTGGCACAGTTTAGGCAGCCGCTTAAAAAGACTGTGCAAAGGTCACAGGTCTCCTCAATATCAG
CTCTTCAAAATGTCACAGGTGGAAGTGATGGGGACACGGTGAGCCACGGTAGTGTGGATAGTTCTAATGATGCTAACAATGGGGAGCACA
CAGTCTTCGTCAGAGATTTAATCAGGCTTGAGTCCATTGATAATCACTCTAGCACAGGTGGTCAGTCTGACCAAGGATACGGGTCTAAGG
ATGAACTTATAAAGGATGATGCAGAAATTCATGTGCCTGAAGAACAGGCAGCAAGAGAATTGATAACTAAAACAAAAATGCAAACAGAAG
AGGTGTGTGATGCCTCTGCTATTGTGGCAAAACATTCACAACCTAGTCCAGAGCCTCACAGTCCTACTGAACCTCCTGCATGGGGCAGCA
GTATTGTGAAAGTTCCGTCTGGTATATTTGATGTCAACAGCAGGAAAAGTAGCACTGGTAGTATATCAAATGTGCTGTTTTCTACTCAAG
ATCCAGTTGAAGATGCAGTCTTTGGCGAAGCTACTAATCTCAAGAAGAATGGTGATAGAGGAGAAAAAAGACAAAAGCATTTTCCTGAGA
GGAGTTGTAGTTTTAGTTCTGAAAGTCGAGCAGGAATGTTGCTTAAGAAGAGTAGTTTGGATTCGAATTCAAGTGAAATGGCTATCATGA
TGGGAGCAGATGCCAAGATTCTCACAGCAGCATTGACATGTCCTAAGACTTCTCTACTTCATATTGCAAGAACCCATAGCTTTGAGAATG
TTAGCTGTCACCTACCTGATAGTAGGACTTGTATGTCTGAAAGCACTTGGAATCCTGAGCACAGATCATCTCCGGTGCCAGAGATGCTTG
AGGAAAGCCAAGAACTCCTTGAGCCTGTGGTTGATGACGTACCTAAAACTACTGCAACAGTAGATACATATGAGAGTCTACTAAGTGATA
GTAACAGTAATCAGTCCAGAGACTTGAAAACAGTATCCAAAGATCTGAGGAATAAGAGAAGTAGTTTATATGGTATTGCTAAGGTGGTTC
AGAGGGAAGATGTTGAAACTGGACTAGATCCTTTGTCTCTTTTAGCCACTGAATGTACAGGAGGAAAAACTCCTGATTCTGAAGATAAGT
TGTTTTCTCCAGTTATTGCACGTAATCTGGCTGATGAAATAGAAAGCTATATGAACCTAAAAAGTCCCCTAGGTAGTAAATCTTCTAGTA
TGGAATTACACAGAGAGGAAAACAGAGAGTCTGGCATGACTACTGCATTTATTCATGCTCTAGAGAGGAGATCAAGCCTACCTTTAGATC
ATGGTTCACCAGCACAGGAAAATCCTGAAAGTGAAAAGAGCTCACCTGCAGTGTCCAGGTCTAAAACTTTTACTGGGCGTTTCAAGCAGC
AAACCCCCTCTCGAACTCATAAAGAACGTTCAACTTCTTTGTCAGCACTGGTGCGTTCTTCGCCACATGGCTCGTTGGGTTCTGTAGTAA
ATTCTTTGTCAGGGCTAAAGCTGGATAATATACTCTCAGGGCCCAAGATAGATGTCCTGAAATCTGGTATGAAACAAGCAGCGACAGTAG
CCAGTAAGATGTGGGTAGCTGTTGCGTCTGCCTACAGCTACTCAGATGATGAGGAAGAAACTAATAGAGACTACAGCTTCCCAGCTGGCC
TAGAAGACCATATTTTGGGGGAGAATATATCGCCTAACACAAGTATCTCAGGGTTGGTCCCCAGTGAACTTACCCAGAGCAACACAAGTC
TTGGCAGTAGCAGCAGTAGTGGAGATGTAGGAAAACTGCATTATCCAACAGGTGAAGTTCCATTTCCAAGAGGCATGAAAGGGCAAGACT
TTGAAAAATCAGATCATGGTTCTTCTCAAAATACCAGCATGTCTAGCATCTATCAGAATTGTGCAATGGAGGTTTTGATGTCCAGTTGTT
CACAGTGTAGAGCTTGTGGAGCTTTAGTTTATGATGAAGAAATTATGGCTGGATGGACAGCAGATGACTCAAATTTGAATACAGCTTGTC
CATTCTGTAAAAGCAACTTCTTGCCTCTTCTCAATATAGAATTCAAAGATTTGAGAGGTTCTGCAAGCTTTTTCCTGAAACCAAGTACCT
CTGGTGACAGTTTACAAAGTGGAAGCATTCCATTGGCAAATGAATCCTTGGAGCACAAACCTGTATCCAGTTTAGCAGAACCTGACTTGA
TCAACTTTATGGACTTCCCAAAACATAACCAGATCATAACTGAAGAAACAGGCTCTGCAGTTGAACCAAGGTCCCGTTTAATGGATTCTG
ACATGGATTATGAAAGGCCAAACGTAGAGACCATCAAGTGCGTTGTGGTGGGGGACAACGCCGTGGGTAAGACCAGGCTCATCTGTGCCC
GCGCTTGCAATGCCACCCTCACCCAGTACCAGCTGCTGGCCACGCATGTGCCCACAGTATGGGCCATCGACCAATATCGTGTGTGCCAGG
AGGTGCTGGAACGCTCCCGAGACGTGGTAGATGATGTCAGCGTCTCTCTGCGCCTCTGGGACACCTTTGGAGACCACCACAAAGACCGTC
GCTTTGCTTATGGGAGATCTGATGTGGTGGTTCTGTGCTTCTCCATTGCCAACCCCAATTCCCTCCACCATGTCAAGACCATGTGGTACC
CAGAAATCAAGCACTTCTGCCCCCGAGCACCTGTCATCTTGGTGGGCTGCCAGTTGGACCTGCGCTACGCTGACCTGGAGGCTGTCAACA
GGGCTAGGCGACCCTTGGCTAGGCCCATCAAACCTAATGAAATCCTGCCCCCAGAGAAGGGTCGGGAGGTGGCCAAGGAGCTGGGCATCC
CCTACTATGAGACCAGCGTGGTGGCCCAGTTCGGCATCAAGGACGTCTTTGACAACGCCATCCGAGCTGCACTCATCTCCCGCCGCCACC
TGCAGTTCTGGAAGTCCCACCTCCGCAATGTGCAGCGGCCTCTGCTGCAGGCACCCTTCCTACCCCCCAAGCCACCGCCCCCGATCATCG
TGGTGCCCGACCCTCCCTCCAGCAGCGAGGAGTGCCCCGCCCACCTCCTGGAGGACCCGCTCTGCGCGGACGTCATCCTGGTGCTGCAGG
AGCGGGTGCGCATCTTTGCCCACAAGATCTACCTCTCCACCTCTTCCTCCAAGTTCTATGACCTGTTCCTCATGGACCTGAGTGAGGGGG
AGCTGGGGGGCCCCTCGGAGCCAGGGGGCACCCACCCAGAGGACCACCAGGGCCACTCTGATCAACACCACCACCATCACCACCACCACC
ATGGGCGAGACTTCCTGCTCCGAGCAGCCAGCTTTGACGTGTGCGAGAGCGTGGATGAGGCTGGGGGCTCCGGTCCTGCTGGCCTCCGTG
CTTCCACCAGCGACGGGATCTTACGGGGCAACGGAACAGGGTACCTACCGGGCAGGGGTCGTGTGCTGTCTTCCTGGAGCCGAGCTTTTG
TGAGCATCCAGGAAGAGATGGCAGAAGATCCTCTCACCTACAAATCCCGGCTGATGGTGGTGGTGAAGATGGACAGTTCCATCCAGCCGG
GGCCCTTCCGGGCTGTCCTCAAGTACCTGTACACGGGGGAGCTAGATGAGAACGAGCGTGACCTCATGCACATTGCCCACATTGCTGAGC
TGCTCGAGGTCTTTGATCTGCGCATGATGGTGGCCAACATTCTCAACAATGAGGCCTTCATGAACCAGGAGATCACCAAGGCCTTCCACG
TCCGCCGGACCAACCGGGTTAAGGAGTGCTTGGCAAAAGGCACCTTCTCAGATGTGACCTTCATCCTGGATGATGGCACCATCAGCGCCC
ACAAGCCCCTGTTGATTTCCAGCTGTGACTGGATGGCTGCCATGTTTGGGGGGCCATTTGTGGAGAGCTCCACCCGGGAGGTGGTGTTTC
CCTACACAAGCAAGAGCTGCATGCGGGCCGTGCTGGAATACCTCTACACCGGCATGTTCACCTCCAGCCCCGACCTGGATGACATGAAGC
TCATCATTCTAGCCAACCGCCTCTGCCTGCCACACCTGGTTGCCCTCACAGAGCAGTACACAGTGACCGGGCTGATGGAAGCGACCCAGA
TGATGGTGGACATCGATGGGGACGTCCTTGTGTTCCTGGAACTGGCTCAGTTCCACTGTGCGTACCAGCTGGCCGACTGGTGTCTCCACC
ACATCTGCACCAACTACAACAACGTGTGCCGCAAGTTCCCCCGAGACATGAAGGCCATGTCCCCAGAAAACCAGGAGTATTTCGAGAAGC
ATCGGTGGCCACCTGTGTGGTACCTGAAGGAGGAAGATCATTACCAGCGGGCACGGAAGGAGCGTGAGAAGGAGGACTACCTCCACCTCA
AGCGGCAGCCCAAACGGCGTTGGCTCTTCTGGAACAGTCCATCCTCCCCGTCTTCCTCGGCAGCCTCCTCCTCATCCCCATCTTCCTCCT
CGGCTGTGGTCTGAGATGCTGCCACCCTCTTCTGACCCTGCTGCTGTTGTCCCCATCCGCCTTCACCCCTCTGCTCTTCCGCATCACCCC
ATCCACCTTACAGGGACCAGGGGGCCCACGTAACCAGGACCCAGAGGGTGGAGCTCTTCTTACCAGCCACCGTGGCTCAGCCAGAGAGGA
GCTGAGCCCTGTGGAGCAGAACGGGAACCACCTGCAGAGGTCCCCAGACCCAAAGCAGGACGGGAGACAACTGCTTGGAGGAGCGAAGAG
CCCTGGCATTTTATCTCTGGGTTTGAGAGCCCTAGAGTCAAAGGGAAAGCCTCCCAGCCTCCAGGGCTTCTCTGTGTGTCTTGGTTGCTG
CTCTGGCCAGGGAGGCAGCCCCACTCCCAGCAAGCAGAAGTGATCCTCGAGGGTCCTGCCCCTGTTGGCCATATCTTTCCACCGACGGAC
TTGAGTGTTGCATTTGTTTTGTGGGCATTTCCACACGAAGCCTACTCACACCCTCACTGGAGAAGTCAGGGTAGAAATTGAGCCTTCAGA
GCCCAACTCAAGGCTTCTACATCCTGGGGTGCAGCTGCAAAAGGCCAGACGTGGAAAGGCCTGTATCCTGCCAGTGTCCCTCCGTCCCAG
GGGGCTGTGCTAGCACAGACCTGAGAATGGGGACACAGGTCATTCAGAGCTCCAGGCCTGGAAGCAGTGCCTCTTGGTGCAACAAGAAAC
TTCTCCCTCACCCCCTCCTTTACCCTCAGATTTGGAGATGGTAACCAAAGGAAGCAGCTGGGACAGGTGGAGAAGGAAGTAGGAATGAGT
GCACGGCGACCCCGTGCTCCTCAGGGCCCTCCCCTGCCTCTGGGTGGCACTGCTTTTTATAGGGTGGGGCAAAATTAGCAAAAAACAAAA

>22263_22263_7_DENND4C-RHOBTB2_DENND4C_chr9_19357152_ENST00000434457_RHOBTB2_chr8_22861938_ENST00000519685_length(amino acids)=2435AA_BP=1697
MRRRRPLELVPRPALPSAPSPRIRCFLAPGRSRVGAALTEEQAAENTVAAMIEDKGPRVTDYFVVAGLTDTSTLLDQEINRLDTKSTGPK
APITDIAIIIKSAGETVPEGYTCVEATPSALQANLNYGSLKSPELFLCYKRGRDKPPLTDIGVLYEGKERLIPGCEVILATPYGRCANVN
NSSTTSQRIFITYRRAPPVRPQNSLAVTDICVIVTSKGETPPHTFCKVDKNLNCGMWGSSVFLCYKKSVPASNAIAYKAGLIFRYPEEDY
ESFPLSESDVPLFCLPMGATIECWDPETKYPLPVFSTFVLTGSSAKKVYGAAIQFYEPYSRELLSEKQLMHLGLLTPVERKMVSKSINTN
KCICLLSHWPFFEAFRKFLMFIYKLSVSGPHPLPIEKHISHFMQNIPFPSPQRPRILVQLSVHDALILSQPVSTPLPLSGANFSTLLMNL
GPENCATLLLFVLLESKILLHSLRPAVLTGVAEAVVAMIFPFQWQCPYIPLCPLSLAAVLSAPLPFIVGVDSRYFDLHDPPQDVVCIDLD
TNMLYVSDEKKNMNWKQLPKKPCKNLLSTLKKLYPQLSSVHQKTQEGSAIDMTPIEADFSWQKKMTQLEMEIQEAFLRFMASILKGYRTY
LRPITEAPSNKATAADSLFDRQGFLKSRDRAYAKFYTLLSKTQIFIRFIEECSFVSDKDTGLAFFDDCIEKLFPDKGTEKTDKVDFDSAE
DTRLIELDDSQKSEHTVFIMPPEPPPDDGKDLSPKYSYKYFPRLDLKLFDRPQELKLCFSRHPTGNSITKSPPLMAKRTKQEIKTAHKLA
KRCYTNPPQWAKCLFSHCYSLWFICLPAYVRVSHPKVRALQQAYDVLIKMRKTDVDPLDEVCYRVVMQLCGLWGHPVLAVRVLFEMKTAR
IKPNAITYGYYNKVVLESPWPSSTRSGIFLWTKVRNVVRGLAQFRQPLKKTVQRSQVSSISALQNVTGGSDGDTVSHGSVDSSNDANNGE
HTVFVRDLIRLESIDNHSSTGGQSDQGYGSKDELIKDDAEIHVPEEQAARELITKTKMQTEEVCDASAIVAKHSQPSPEPHSPTEPPAWG
SSIVKVPSGIFDVNSRKSSTGSISNVLFSTQDPVEDAVFGEATNLKKNGDRGEKRQKHFPERSCSFSSESRAGMLLKKSSLDSNSSEMAI
MMGADAKILTAALTCPKTSLLHIARTHSFENVSCHLPDSRTCMSESTWNPEHRSSPVPEMLEESQELLEPVVDDVPKTTATVDTYESLLS
DSNSNQSRDLKTVSKDLRNKRSSLYGIAKVVQREDVETGLDPLSLLATECTGGKTPDSEDKLFSPVIARNLADEIESYMNLKSPLGSKSS
SMELHREENRESGMTTAFIHALERRSSLPLDHGSPAQENPESEKSSPAVSRSKTFTGRFKQQTPSRTHKERSTSLSALVRSSPHGSLGSV
VNSLSGLKLDNILSGPKIDVLKSGMKQAATVASKMWVAVASAYSYSDDEEETNRDYSFPAGLEDHILGENISPNTSISGLVPSELTQSNT
SLGSSSSSGDVGKLHYPTGEVPFPRGMKGQDFEKSDHGSSQNTSMSSIYQNCAMEVLMSSCSQCRACGALVYDEEIMAGWTADDSNLNTA
CPFCKSNFLPLLNIEFKDLRGSASFFLKPSTSGDSLQSGSIPLANESLEHKPVSSLAEPDLINFMDFPKHNQIITEETGSAVEPRSRLMD
SDMDYERPNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDDVSVSLRLWDTFGDHHKD
RRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKELG
IPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQAPFLPPKPPPPIIVVPDPPSSSEECPAHLLEDPLCADVILVL
QERVRIFAHKIYLSTSSSKFYDLFLMDLSEGELGGPSEPGGTHPEDHQGHSDQHHHHHHHHHGRDFLLRAASFDVCESVDEAGGSGPAGL
RASTSDGILRGNGTGYLPGRGRVLSSWSRAFVSIQEEMAEDPLTYKSRLMVVVKMDSSIQPGPFRAVLKYLYTGELDENERDLMHIAHIA
ELLEVFDLRMMVANILNNEAFMNQEITKAFHVRRTNRVKECLAKGTFSDVTFILDDGTISAHKPLLISSCDWMAAMFGGPFVESSTREVV
FPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIILANRLCLPHLVALTEQYTVTGLMEATQMMVDIDGDVLVFLELAQFHCAYQLADWCL
HHICTNYNNVCRKFPRDMKAMSPENQEYFEKHRWPPVWYLKEEDHYQRARKEREKEDYLHLKRQPKRRWLFWNSPSSPSSSAASSSSPSS

--------------------------------------------------------------
>22263_22263_8_DENND4C-RHOBTB2_DENND4C_chr9_19357152_ENST00000434457_RHOBTB2_chr8_22861938_ENST00000522948_length(transcript)=10297nt_BP=5380nt
GGAGGAAAGGGAGAGGGAGGGGGAAAAGAAAGTGCTGTTTTGTGGAAAGGGGCGGAAGGCGGGGGAGAAAAAGGGAACAGAAACATGGCG
GTCAGGTCTTGGGACGGCTGCGCCGCGGGCAGCTCCTAGGCGACGCGCCGCCCGCACTGTCCGACGGCTCACAGCGCGGAGGCACCCGCG
CGGGCCAGCGCTCCGGCCATCGCCCCTGGCTGTAGGCGGCGCCCCTCGGAGACCCTGCCCGCGAGGCGGCGCAGGCGCAGACCGGACTGA
GGCGGCGGCGGCCGCTGGAGCTAGTCCCCCGCCCTGCCCTGCCGAGCGCGCCCAGTCCGCGAATCCGGTGCTTTCTTGCCCCAGGAAGAA
GCCGTGTCGGGGCTGCGCTGACAGAGGAGCAGGCAGCAGAAAATACAGTAGCAGCCATGATAGAAGACAAAGGACCAAGAGTGACAGACT
ACTTTGTCGTAGCTGGTCTCACTGACACATCTACTCTTTTGGATCAAGAAATAAATCGTTTAGATACTAAGTCAACTGGACCTAAAGCTC
CAATTACAGACATTGCCATTATTATCAAATCAGCTGGAGAAACAGTACCTGAAGGTTACACCTGTGTAGAAGCCACTCCATCAGCTCTCC
AAGCAAACTTGAACTATGGAAGTCTGAAAAGCCCAGAACTTTTCCTCTGTTATAAGAGAGGGAGAGATAAACCACCGCTTACAGATATTG
GAGTTCTATATGAAGGGAAAGAACGGCTTATTCCAGGATGTGAAGTGATCCTAGCCACACCCTATGGTCGCTGTGCCAATGTCAACAATA
GTTCAACTACTTCACAAAGAATCTTTATCACTTATCGAAGGGCTCCTCCAGTTCGACCCCAGAATTCCTTGGCTGTAACTGATATCTGTG
TTATTGTAACCAGTAAAGGAGAAACTCCTCCTCATACCTTCTGCAAAGTTGACAAAAACTTAAATTGTGGAATGTGGGGTTCCAGCGTGT
TTCTGTGTTATAAGAAGTCTGTACCTGCTTCAAATGCAATAGCATATAAGGCTGGTTTAATTTTTAGATATCCAGAAGAGGACTATGAGT
CATTTCCACTCTCAGAATCAGATGTACCTCTTTTCTGCCTTCCTATGGGAGCTACTATTGAGTGCTGGGATCCTGAAACCAAATATCCAC
TTCCAGTTTTTTCAACTTTTGTCTTGACAGGTTCTTCAGCCAAAAAGGTATATGGAGCTGCCATTCAGTTTTATGAACCTTACTCTCGGG
AACTTCTATCAGAGAAACAGCTTATGCACCTGGGCTTGTTGACGCCTGTGGAGAGAAAAATGGTCTCCAAATCCATCAATACAAACAAAT
GCATTTGTTTACTCTCACACTGGCCTTTTTTTGAAGCTTTTAGGAAATTTCTTATGTTTATCTACAAACTTTCTGTGTCTGGACCACATC
CTCTTCCCATTGAAAAGCACATTTCACATTTTATGCAAAACATCCCTTTTCCTTCACCACAAAGACCGAGAATCCTTGTCCAGCTGTCAG
TCCATGATGCATTAATATTATCACAGCCAGTTTCTACACCTTTACCACTAAGTGGAGCCAACTTTAGCACCTTGCTAATGAATCTGGGTC
CTGAGAATTGTGCAACACTGCTGCTCTTTGTTTTACTTGAGAGTAAAATTCTGCTGCATTCTCTTAGGCCAGCTGTCTTGACTGGGGTAG
CTGAAGCTGTTGTAGCTATGATCTTTCCATTTCAGTGGCAATGCCCATATATTCCCCTTTGTCCTCTTTCACTGGCTGCAGTGCTTAGTG
CACCTTTACCATTTATAGTTGGAGTTGACTCAAGGTATTTTGATCTTCATGACCCACCACAAGATGTTGTTTGCATTGACTTGGATACGA
ACATGTTATATGTATCAGATGAAAAGAAGAACATGAACTGGAAGCAACTTCCCAAAAAGCCGTGCAAAAATCTACTTAGCACCTTAAAGA
AATTGTATCCCCAGCTGTCTTCAGTTCACCAAAAAACTCAAGAAGGCTCAGCGATTGACATGACTCCAATTGAAGCAGATTTCTCCTGGC
AAAAGAAGATGACACAGCTTGAGATGGAAATTCAAGAGGCATTTTTGCGCTTTATGGCGTCTATTTTAAAAGGATATAGAACATATCTCA
GACCAATCACAGAGGCTCCTTCAAATAAAGCCACAGCTGCTGATTCATTGTTTGACCGACAGGGATTTTTAAAAAGTCGAGATCGTGCCT
ATGCAAAATTCTATACCCTTTTATCCAAAACACAGATTTTTATTCGTTTCATTGAAGAATGCAGTTTTGTAAGTGATAAAGATACTGGAT
TAGCATTTTTTGATGACTGCATAGAAAAGTTGTTTCCTGATAAAGGCACAGAGAAAACAGATAAGGTTGATTTTGATTCAGCAGAAGATA
CCAGATTGATAGAACTAGATGATTCACAGAAAAGTGAGCATACTGTATTTATAATGCCGCCAGAGCCACCTCCTGATGATGGAAAGGACC
TGTCACCAAAGTACAGTTACAAATACTTTCCAAGACTGGACCTTAAGCTTTTTGACAGACCGCAGGAGTTGAAACTTTGTTTTAGTAGAC
ACCCTACTGGGAATAGCATTACAAAGAGTCCACCTCTCATGGCTAAGAGAACTAAACAGGAAATAAAAACAGCTCATAAATTGGCGAAGA
GATGTTATACAAATCCACCACAGTGGGCCAAGTGTCTGTTTAGTCATTGTTACAGTTTATGGTTTATTTGTCTTCCGGCCTATGTTAGAG
TTTCTCATCCTAAAGTCAGAGCACTTCAGCAGGCATATGATGTACTTATTAAGATGAGGAAAACAGATGTGGATCCCTTAGATGAGGTGT
GCTATCGAGTAGTGATGCAGCTTTGTGGACTTTGGGGTCATCCTGTTTTAGCAGTGAGAGTCTTATTTGAAATGAAAACTGCTAGGATAA
AGCCTAATGCTATTACTTATGGTTATTATAATAAGGTAGTCTTGGAGAGCCCGTGGCCTAGCAGTACCCGCAGTGGTATTTTCTTATGGA
CGAAGGTACGGAATGTGGTACGTGGCTTGGCACAGTTTAGGCAGCCGCTTAAAAAGACTGTGCAAAGGTCACAGGTCTCCTCAATATCAG
CTCTTCAAAATGTCACAGGTGGAAGTGATGGGGACACGGTGAGCCACGGTAGTGTGGATAGTTCTAATGATGCTAACAATGGGGAGCACA
CAGTCTTCGTCAGAGATTTAATCAGGCTTGAGTCCATTGATAATCACTCTAGCACAGGTGGTCAGTCTGACCAAGGATACGGGTCTAAGG
ATGAACTTATAAAGGATGATGCAGAAATTCATGTGCCTGAAGAACAGGCAGCAAGAGAATTGATAACTAAAACAAAAATGCAAACAGAAG
AGGTGTGTGATGCCTCTGCTATTGTGGCAAAACATTCACAACCTAGTCCAGAGCCTCACAGTCCTACTGAACCTCCTGCATGGGGCAGCA
GTATTGTGAAAGTTCCGTCTGGTATATTTGATGTCAACAGCAGGAAAAGTAGCACTGGTAGTATATCAAATGTGCTGTTTTCTACTCAAG
ATCCAGTTGAAGATGCAGTCTTTGGCGAAGCTACTAATCTCAAGAAGAATGGTGATAGAGGAGAAAAAAGACAAAAGCATTTTCCTGAGA
GGAGTTGTAGTTTTAGTTCTGAAAGTCGAGCAGGAATGTTGCTTAAGAAGAGTAGTTTGGATTCGAATTCAAGTGAAATGGCTATCATGA
TGGGAGCAGATGCCAAGATTCTCACAGCAGCATTGACATGTCCTAAGACTTCTCTACTTCATATTGCAAGAACCCATAGCTTTGAGAATG
TTAGCTGTCACCTACCTGATAGTAGGACTTGTATGTCTGAAAGCACTTGGAATCCTGAGCACAGATCATCTCCGGTGCCAGAGATGCTTG
AGGAAAGCCAAGAACTCCTTGAGCCTGTGGTTGATGACGTACCTAAAACTACTGCAACAGTAGATACATATGAGAGTCTACTAAGTGATA
GTAACAGTAATCAGTCCAGAGACTTGAAAACAGTATCCAAAGATCTGAGGAATAAGAGAAGTAGTTTATATGGTATTGCTAAGGTGGTTC
AGAGGGAAGATGTTGAAACTGGACTAGATCCTTTGTCTCTTTTAGCCACTGAATGTACAGGAGGAAAAACTCCTGATTCTGAAGATAAGT
TGTTTTCTCCAGTTATTGCACGTAATCTGGCTGATGAAATAGAAAGCTATATGAACCTAAAAAGTCCCCTAGGTAGTAAATCTTCTAGTA
TGGAATTACACAGAGAGGAAAACAGAGAGTCTGGCATGACTACTGCATTTATTCATGCTCTAGAGAGGAGATCAAGCCTACCTTTAGATC
ATGGTTCACCAGCACAGGAAAATCCTGAAAGTGAAAAGAGCTCACCTGCAGTGTCCAGGTCTAAAACTTTTACTGGGCGTTTCAAGCAGC
AAACCCCCTCTCGAACTCATAAAGAACGTTCAACTTCTTTGTCAGCACTGGTGCGTTCTTCGCCACATGGCTCGTTGGGTTCTGTAGTAA
ATTCTTTGTCAGGGCTAAAGCTGGATAATATACTCTCAGGGCCCAAGATAGATGTCCTGAAATCTGGTATGAAACAAGCAGCGACAGTAG
CCAGTAAGATGTGGGTAGCTGTTGCGTCTGCCTACAGCTACTCAGATGATGAGGAAGAAACTAATAGAGACTACAGCTTCCCAGCTGGCC
TAGAAGACCATATTTTGGGGGAGAATATATCGCCTAACACAAGTATCTCAGGGTTGGTCCCCAGTGAACTTACCCAGAGCAACACAAGTC
TTGGCAGTAGCAGCAGTAGTGGAGATGTAGGAAAACTGCATTATCCAACAGGTGAAGTTCCATTTCCAAGAGGCATGAAAGGGCAAGACT
TTGAAAAATCAGATCATGGTTCTTCTCAAAATACCAGCATGTCTAGCATCTATCAGAATTGTGCAATGGAGGTTTTGATGTCCAGTTGTT
CACAGTGTAGAGCTTGTGGAGCTTTAGTTTATGATGAAGAAATTATGGCTGGATGGACAGCAGATGACTCAAATTTGAATACAGCTTGTC
CATTCTGTAAAAGCAACTTCTTGCCTCTTCTCAATATAGAATTCAAAGATTTGAGAGGTTCTGCAAGCTTTTTCCTGAAACCAAGTACCT
CTGGTGACAGTTTACAAAGTGGAAGCATTCCATTGGCAAATGAATCCTTGGAGCACAAACCTGTATCCAGTTTAGCAGAACCTGACTTGA
TCAACTTTATGGACTTCCCAAAACATAACCAGATCATAACTGAAGAAACAGGCTCTGCAGTTGAACCAAGGTCCCGTTTAATGGATTCTG
ACATGGATTATGAAAGGCCAAACGTAGAGACCATCAAGTGCGTTGTGGTGGGGGACAACGCCGTGGGTAAGACCAGGCTCATCTGTGCCC
GCGCTTGCAATGCCACCCTCACCCAGTACCAGCTGCTGGCCACGCATGTGCCCACAGTATGGGCCATCGACCAATATCGTGTGTGCCAGG
AGGTGCTGGAACGCTCCCGAGACGTGGTAGATGATGTCAGCGTCTCTCTGCGCCTCTGGGACACCTTTGGAGACCACCACAAAGACCGTC
GCTTTGCTTATGGGAGATCTGATGTGGTGGTTCTGTGCTTCTCCATTGCCAACCCCAATTCCCTCCACCATGTCAAGACCATGTGGTACC
CAGAAATCAAGCACTTCTGCCCCCGAGCACCTGTCATCTTGGTGGGCTGCCAGTTGGACCTGCGCTACGCTGACCTGGAGGCTGTCAACA
GGGCTAGGCGACCCTTGGCTAGGCCCATCAAACCTAATGAAATCCTGCCCCCAGAGAAGGGTCGGGAGGTGGCCAAGGAGCTGGGCATCC
CCTACTATGAGACCAGCGTGGTGGCCCAGTTCGGCATCAAGGACGTCTTTGACAACGCCATCCGAGCTGCACTCATCTCCCGCCGCCACC
TGCAGTTCTGGAAGTCCCACCTCCGCAATGTGCAGCGGCCTCTGCTGCAGGCACCCTTCCTACCCCCCAAGCCACCGCCCCCGATCATCG
TGGTGCCCGACCCTCCCTCCAGCAGCGAGGAGTGCCCCGCCCACCTCCTGGAGGACCCGCTCTGCGCGGACGTCATCCTGGTGCTGCAGG
AGCGGGTGCGCATCTTTGCCCACAAGATCTACCTCTCCACCTCTTCCTCCAAGTTCTATGACCTGTTCCTCATGGACCTGAGTGAGGGGG
AGCTGGGGGGCCCCTCGGAGCCAGGGGGCACCCACCCAGAGGACCACCAGGGCCACTCTGATCAACACCACCACCATCACCACCACCACC
ATGGGCGAGACTTCCTGCTCCGAGCAGCCAGCTTTGACGTGTGCGAGAGCGTGGATGAGGCTGGGGGCTCCGGTCCTGCTGGCCTCCGTG
CTTCCACCAGCGACGGGATCTTACGGGGCAACGGAACAGGGTACCTACCGGGCAGGGGTCGTGTGCTGTCTTCCTGGAGCCGAGCTTTTG
TGAGCATCCAGGAAGAGATGGCAGAAGATCCTCTCACCTACAAATCCCGGCTGATGGTGGTGGTGAAGATGGACAGTTCCATCCAGCCGG
GGCCCTTCCGGGCTGTCCTCAAGTACCTGTACACGGGGGAGCTAGATGAGAACGAGCGTGACCTCATGCACATTGCCCACATTGCTGAGC
TGCTCGAGGTCTTTGATCTGCGCATGATGGTGGCCAACATTCTCAACAATGAGGCCTTCATGAACCAGGAGATCACCAAGGCCTTCCACG
TCCGCCGGACCAACCGGGTTAAGGAGTGCTTGGCAAAAGGCACCTTCTCAGATGTGACCTTCATCCTGGATGATGGCACCATCAGCGCCC
ACAAGCCCCTGTTGATTTCCAGCTGTGACTGGATGGCTGCCATGTTTGGGGGGCCATTTGTGGAGAGCTCCACCCGGGAGGTGGTGTTTC
CCTACACAAGCAAGAGCTGCATGCGGGCCGTGCTGGAATACCTCTACACCGGCATGTTCACCTCCAGCCCCGACCTGGATGACATGAAGC
TCATCATTCTAGCCAACCGCCTCTGCCTGCCACACCTGGTTGCCCTCACAGAGCAGTACACAGTGACCGGGCTGATGGAAGCGACCCAGA
TGATGGTGGACATCGATGGGGACGTCCTTGTGTTCCTGGAACTGGCTCAGTTCCACTGTGCGTACCAGCTGGCCGACTGGTGTCTCCACC
ACATCTGCACCAACTACAACAACGTGTGCCGCAAGTTCCCCCGAGACATGAAGGCCATGTCCCCAGAAAACCAGGAGTATTTCGAGAAGC
ATCGGTGGCCACCTGTGTGGTACCTGAAGGAGGAAGATCATTACCAGCGGGCACGGAAGGAGCGTGAGAAGGAGGACTACCTCCACCTCA
AGCGGCAGCCCAAACGGCGTTGGCTCTTCTGGAACAGTCCATCCTCCCCGTCTTCCTCGGCAGCCTCCTCCTCATCCCCATCTTCCTCCT
CGGCTGTGGTCTGAGATGCTGCCACCCTCTTCTGACCCTGCTGCTGTTGTCCCCATCCGCCTTCACCCCTCTGCTCTTCCGCATCACCCC
ATCCACCTTACAGGGACCAGGGGGCCCACGTAACCAGGACCCAGAGGGTGGAGCTCTTCTTACCAGCCACCGTGGCTCAGCCAGAGAGGA
GCTGAGCCCTGTGGAGCAGAACGGGAACCACCTGCAGAGGTCCCCAGACCCAAAGCAGGACGGGAGACAACTGCTTGGAGGAGCGAAGAG
CCCTGGCATTTTATCTCTGGGTTTGAGAGCCCTAGAGTCAAAGGGAAAGCCTCCCAGCCTCCAGGGCTTCTCTGTGTGTCTTGGTTGCTG
CTCTGGCCAGGGAGGCAGCCCCACTCCCAGCAAGCAGAAGTGATCCTCGAGGGTCCTGCCCCTGTTGGCCATATCTTTCCACCGACGGAC
TTGAGTGTTGCATTTGTTTTGTGGGCATTTCCACACGAAGCCTACTCACACCCTCACTGGAGAAGTCAGGGTAGAAATTGAGCCTTCAGA
GCCCAACTCAAGGCTTCTACATCCTGGGGTGCAGCTGCAAAAGGCCAGACGTGGAAAGGCCTGTATCCTGCCAGTGTCCCTCCGTCCCAG
GGGGCTGTGCTAGCACAGACCTGAGAATGGGGACACAGGTCATTCAGAGCTCCAGGCCTGGAAGCAGTGCCTCTTGGTGCAACAAGAAAC
TTCTCCCTCACCCCCTCCTTTACCCTCAGATTTGGAGATGGTAACCAAAGGAAGCAGCTGGGACAGGTGGAGAAGGAAGTAGGAATGAGT
GCACGGCGACCCCGTGCTCCTCAGGGCCCTCCCCTGCCTCTGGGTGGCACTGCTTTTTATAGGGTGGGGCAAAATTAGCAAAAAACAAAA
ACCAATGACAACCAAACTGAAACCGAAACGAAAAATCAACAAACACTCTGTCCTCTATCCCTCCAAAGAATGAAAATCAGAAAAAGCCCC
TGCCTAGCTCACATTTCTATAAACAGAGGCCCCCATGATGAGGAGGTGAAGATTTAGGTTGCAGAATCGACTCCAATGCCTTTCAGGAAA
GGACTCGGCACTTCTCTGACTGCGGAGGCCCTGACCCTGCCAGCTGGCTCCGAGGGCAACACAGGGGCCTGGCCTCTAGAGGGCTGGTGA
TTGAGGGGCCCGGGCTGGCGGCAAAGAGGGGTTTGGTCTCGGGGCTTAAATGGCACCAGACTCTTGCTTTTGCCCATCTGGAGACTGCAG
GCTCCCTTCCTTACCCTCAGAGAGTGCTTATGGTGGGTGTTTTTGCGGGGCTGCAATAGGGGCCAAAAGTCAGGGAAAGGGGCACTGACC
TGTAGTGAAAGGCCACAGGACACAGCCTTATTACTGCTGGGGTGGGATAAGGGGAAGGAGAAGAGGGAGAATGGAGCAGGAGGAAAAGCA
GAGTTGGTCTAGAGAGGAGGAGGGCGGGGCTGGAGGAATGTGGGGGATTGAAACTAGCTCCCAGCCCCCATGGGGCAGCAGCTGGGCCAC
AATTGCCCCTTTCCGTTTTCTAACCCCGACTCAGATTTCACCACCCACACTCTTTTTAGGTGTAAAAGATGGAGTCCCACGGAGGAGGGG
CAGAGCCAGGAGGCAGTGGGGCTGTGGGCTCAGAGCTCAGGAGTCGCCTTACCTGAGAGAGATGTTCTAGCTGAGAGGGCCTGGCCCTGG
GGTGGGCTCCAGGAAAACGCTGGTTAGGCCTGGGATTGAGCTAACCTGAAACAAAGGTAGCAGGCAGGACCTAATGACCAGAGGTTAAAT
CCTCATCAAGAGAGACCAGGCGGCTGGAGGACAAGCGGCTCTAACCCTGGGGGCGGCCATGTTGTCCAGGCCCAGGCCCCTCCAGGACTG
TGGCTGCCTCCCCTCCACGGCCTCCAGGGCGGCTGGCTGGAAAGCCACGCGTATGCTGCCCTCTACAGGCTGCTCGGCCTCCCTGCAGCT
CAGCGCAGCCCAGGGCTCCAAGTGAGGCCCAGAAGCCCATGGGCAGGGCTGGGGGGACGAAGGGGGAACCCGGAGCACCTCCACTTCTAG
GGAAGATGGACAGCGTGGGGGCACACCTGGGCCTCCCGGAAGCTGTGGACGAAAGGGAGAGCGGGTCCTCCAGGGCAAGGGGAACGGGAA
ATAGGTCTCCTAGGTGCCTGAAGCGCTGAGCAACCTGGGTACCCTGGTGGGGATGCAGGGAAGGCCGGGGCAGAGAAAGTGAAGGTCGAC
CCAGGGCTGTAGGAAGCCATAGGAGAGTGACCACGGGATTCCCTGAGAAACAGGGCCGGCCCCCCAACTTCAGGGACCCACCGCCCATTC
CCCGAGAGCTGTCGGAACCAGATGCAACCCGGCAGCCCAGAGAACTCTCCTGGGAGGCTGTGGGTGAGCCAGGCCAACATTGGTGTCCCT
GTCCCCAGAGGGAGGAGCAGGCAGGAGAGAGAGGGGAAGGAGGTATGAATCCCAGTCCCCAGGAACCTAGCTCTTTAAACTCTGGGGAGT
CGGATTCAGGAAACACCCCCAGGAGGCCAAGCCTGAAAACAGAGGGGAGGGAGGAAGGAAGGAGTCCCAGCAGGAGCACAGCCCTGGTTT
CCTGTCACTCAGAGCTGATTCACAGGAGGAGGGGAGGTTGGGGGGCGGGAGACAAAAACCACACCTCTTTTTATATAAGGTTTCATATTT

>22263_22263_8_DENND4C-RHOBTB2_DENND4C_chr9_19357152_ENST00000434457_RHOBTB2_chr8_22861938_ENST00000522948_length(amino acids)=2435AA_BP=1697
MRRRRPLELVPRPALPSAPSPRIRCFLAPGRSRVGAALTEEQAAENTVAAMIEDKGPRVTDYFVVAGLTDTSTLLDQEINRLDTKSTGPK
APITDIAIIIKSAGETVPEGYTCVEATPSALQANLNYGSLKSPELFLCYKRGRDKPPLTDIGVLYEGKERLIPGCEVILATPYGRCANVN
NSSTTSQRIFITYRRAPPVRPQNSLAVTDICVIVTSKGETPPHTFCKVDKNLNCGMWGSSVFLCYKKSVPASNAIAYKAGLIFRYPEEDY
ESFPLSESDVPLFCLPMGATIECWDPETKYPLPVFSTFVLTGSSAKKVYGAAIQFYEPYSRELLSEKQLMHLGLLTPVERKMVSKSINTN
KCICLLSHWPFFEAFRKFLMFIYKLSVSGPHPLPIEKHISHFMQNIPFPSPQRPRILVQLSVHDALILSQPVSTPLPLSGANFSTLLMNL
GPENCATLLLFVLLESKILLHSLRPAVLTGVAEAVVAMIFPFQWQCPYIPLCPLSLAAVLSAPLPFIVGVDSRYFDLHDPPQDVVCIDLD
TNMLYVSDEKKNMNWKQLPKKPCKNLLSTLKKLYPQLSSVHQKTQEGSAIDMTPIEADFSWQKKMTQLEMEIQEAFLRFMASILKGYRTY
LRPITEAPSNKATAADSLFDRQGFLKSRDRAYAKFYTLLSKTQIFIRFIEECSFVSDKDTGLAFFDDCIEKLFPDKGTEKTDKVDFDSAE
DTRLIELDDSQKSEHTVFIMPPEPPPDDGKDLSPKYSYKYFPRLDLKLFDRPQELKLCFSRHPTGNSITKSPPLMAKRTKQEIKTAHKLA
KRCYTNPPQWAKCLFSHCYSLWFICLPAYVRVSHPKVRALQQAYDVLIKMRKTDVDPLDEVCYRVVMQLCGLWGHPVLAVRVLFEMKTAR
IKPNAITYGYYNKVVLESPWPSSTRSGIFLWTKVRNVVRGLAQFRQPLKKTVQRSQVSSISALQNVTGGSDGDTVSHGSVDSSNDANNGE
HTVFVRDLIRLESIDNHSSTGGQSDQGYGSKDELIKDDAEIHVPEEQAARELITKTKMQTEEVCDASAIVAKHSQPSPEPHSPTEPPAWG
SSIVKVPSGIFDVNSRKSSTGSISNVLFSTQDPVEDAVFGEATNLKKNGDRGEKRQKHFPERSCSFSSESRAGMLLKKSSLDSNSSEMAI
MMGADAKILTAALTCPKTSLLHIARTHSFENVSCHLPDSRTCMSESTWNPEHRSSPVPEMLEESQELLEPVVDDVPKTTATVDTYESLLS
DSNSNQSRDLKTVSKDLRNKRSSLYGIAKVVQREDVETGLDPLSLLATECTGGKTPDSEDKLFSPVIARNLADEIESYMNLKSPLGSKSS
SMELHREENRESGMTTAFIHALERRSSLPLDHGSPAQENPESEKSSPAVSRSKTFTGRFKQQTPSRTHKERSTSLSALVRSSPHGSLGSV
VNSLSGLKLDNILSGPKIDVLKSGMKQAATVASKMWVAVASAYSYSDDEEETNRDYSFPAGLEDHILGENISPNTSISGLVPSELTQSNT
SLGSSSSSGDVGKLHYPTGEVPFPRGMKGQDFEKSDHGSSQNTSMSSIYQNCAMEVLMSSCSQCRACGALVYDEEIMAGWTADDSNLNTA
CPFCKSNFLPLLNIEFKDLRGSASFFLKPSTSGDSLQSGSIPLANESLEHKPVSSLAEPDLINFMDFPKHNQIITEETGSAVEPRSRLMD
SDMDYERPNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDDVSVSLRLWDTFGDHHKD
RRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKELG
IPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQAPFLPPKPPPPIIVVPDPPSSSEECPAHLLEDPLCADVILVL
QERVRIFAHKIYLSTSSSKFYDLFLMDLSEGELGGPSEPGGTHPEDHQGHSDQHHHHHHHHHGRDFLLRAASFDVCESVDEAGGSGPAGL
RASTSDGILRGNGTGYLPGRGRVLSSWSRAFVSIQEEMAEDPLTYKSRLMVVVKMDSSIQPGPFRAVLKYLYTGELDENERDLMHIAHIA
ELLEVFDLRMMVANILNNEAFMNQEITKAFHVRRTNRVKECLAKGTFSDVTFILDDGTISAHKPLLISSCDWMAAMFGGPFVESSTREVV
FPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIILANRLCLPHLVALTEQYTVTGLMEATQMMVDIDGDVLVFLELAQFHCAYQLADWCL
HHICTNYNNVCRKFPRDMKAMSPENQEYFEKHRWPPVWYLKEEDHYQRARKEREKEDYLHLKRQPKRRWLFWNSPSSPSSSAASSSSPSS

--------------------------------------------------------------
>22263_22263_9_DENND4C-RHOBTB2_DENND4C_chr9_19357152_ENST00000602925_RHOBTB2_chr8_22861937_ENST00000519685_length(transcript)=8399nt_BP=5233nt
GGAGGAAAGGGAGAGGGAGGGGGAAAAGAAAGTGCTGTTTTGTGGAAAGGGGCGGAAGGCGGGGGAGAAAAAGGGAACAGAAACATGGCG
GTCAGGTCTTGGGACGGCTGCGCCGCGGGCAGCTCCTAGGCGACGCGCCGCCCGCACTGTCCGACGGCTCACAGCGCGGAGGCACCCGCG
CGGGCCAGCGCTCCGGCCATCGCCCCTGGCTGTAGGCGGCGCCCCTCGGAGACCCTGCCCGCGAGGCGGCGCAGGCGCAGACCGGACTGA
GGCGGCGGCGGCCGCTGGAGCTAGTCCCCCGCCCTGCCCTGCCGAGCGCGCCCAGTCCGCGAATCCGGTGCTTTCTTGCCCCAGGAAGAA
GCCGTGTCGGGGCTGCGCTGACAGAGGAGCAGGCAGCAGAAAATACAGTAGCAGCCATGATAGAAGACAAAGGACCAAGAGTGACAGACT
ACTTTGTCGTAGCTGGTCTCACTGACACATCTACTCTTTTGGATCAAGAAATAAATCGTTTAGATACTAAGTCAACTGGACCTAAAGCTC
CAATTACAGACATTGCCATTATTATCAAATCAGCTGGAGAAACAGTACCTGAAGGTTACACCTGTGTAGAAGCCACTCCATCAGCTCTCC
AAGCAAACTTGAACTATGGAAGTCTGAAAAGCCCAGAACTTTTCCTCTGTTATAAGAGAGGGAGAGATAAACCACCGCTTACAGATATTG
GAGTTCTATATGAAGGGAAAGAACGGCTTATTCCAGGATGTGAAGTGATCCTAGCCACACCCTATGGTCGCTGTGCCAATGTCAACAATA
GTTCAACTACTTCACAAAGAATCTTTATCACTTATCGAAGGGCTCCTCCAGTTCGACCCCAGAATTCCTTGGCTGTAACTGATATCTGTG
TTATTGTAACCAGTAAAGGAGAAACTCCTCCTCATACCTTCTGCAAAGTTGACAAAAACTTAAATTGTGGAATGTGGGGTTCCAGCGTGT
TTCTGTGTTATAAGAAGTCTGTACCTGCTTCAAATGCAATAGCATATAAGGCTGGTTTAATTTTTAGATATCCAGAAGAGGACTATGAGT
CATTTCCACTCTCAGAATCAGATGTACCTCTTTTCTGCCTTCCTATGGGAGCTACTATTGAGTGCTGGGATCCTGAAACCAAATATCCAC
TTCCAGTTTTTTCAACTTTTGTCTTGACAGGTTCTTCAGCCAAAAAGGTATATGGAGCTGCCATTCAGTTTTATGAACCTTACTCTCGGG
AACTTCTATCAGAGAAACAGCTTATGCACCTGGGCTTGTTGACGCCTGTGGAGAGAAAAATGGTCTCCAAATCCATCAATACAAACAAAT
GCATTTGTTTACTCTCACACTGGCCTTTTTTTGAAGCTTTTAGGAAATTTCTTATGTTTATCTACAAACTTTCTGTGTCTGGACCACATC
CTCTTCCCATTGAAAAGCACATTTCACATTTTATGCAAAACATCCCTTTTCCTTCACCACAAAGACCGAGAATCCTTGTCCAGCTGTCAG
TCCATGATGCATTAATATTATCACAGCCAGTTTCTACACCTTTACCACTAAGTGGAGCCAACTTTAGCACCTTGCTAATGAATCTGGGTC
CTGAGAATTGTGCAACACTGCTGCTCTTTGTTTTACTTGAGAGTAAAATTCTGCTGCATTCTCTTAGGCCAGCTGTCTTGACTGGGGTAG
CTGAAGCTGTTGTAGCTATGATCTTTCCATTTCAGTGGCAATGCCCATATATTCCCCTTTGTCCTCTTTCACTGGCTGCAGTGCTTAGTG
CACCTTTACCATTTATAGTTGGAGTTGACTCAAGGTATTTTGATCTTCATGACCCACCACAAGATGTTGTTTGCATTGACTTGGATACGA
ACATGTTATATGTATCAGATGAAAAGAAGAACATGAACTGGAAGCAACTTCCCAAAAAGCCGTGCAAAAATCTACTTAGCACCTTAAAGA
AATTGTATCCCCAGCTGTCTTCAGTTCACCAAAAAACTCAAGAAGGCTCAGCGATTGACATGACTCCAATTGAAGCAGATTTCTCCTGGC
AAAAGAAGATGACACAGCTTGAGATGGAAATTCAAGAGGCATTTTTGCGCTTTATGGCGTCTATTTTAAAAGGATATAGAACATATCTCA
GACCAATCACAGAGGCTCCTTCAAATAAAGCCACAGCTGCTGATTCATTGTTTGACCGACAGGGATTTTTAAAAAGTCGAGATCGTGCCT
ATGCAAAATTCTATACCCTTTTATCCAAAACACAGATTTTTATTCGTTTCATTGAAGAATGCAGTTTTGTAAGTGATAAAGATACTGGAT
TAGCATTTTTTGATGACTGCATAGAAAAGTTGTTTCCTGATAAAGGCACAGAGAAAACAGATAAGGTTGATTTTGATTCAGCAGAAGATA
CCAGATTGATAGAACTAGATGATTCACAGAAAAGTGAGCATACTGTATTTATAATGCCGCCAGAGCCACCTCCTGATGATGGAAAGGACC
TGTCACCAAAGTACAGTTACAAATACTTTCCAAGACTGGACCTTAAGCTTTTTGACAGACCGCAGGAGTTGAAACTTTGTTTTAGTAGAC
ACCCTACTGGGAATAGCATTACAAAGAGTCCACCTCTCATGGCTAAGAGAACTAAACAGGAAATAAAAACAGCTCATAAATTGGCGAAGA
GATGTTATACAAATCCACCACAGTGGGCCAAGTGTCTGTTTAGTCATTGTTACAGTTTATGGTTTATTTGTCTTCCGGCCTATGTTAGAG
TTTCTCATCCTAAAGTCAGAGCACTTCAGCAGGCATATGATGTACTTATTAAGATGAGGAAAACAGATGTGGATCCCTTAGATGAGGTGT
GCTATCGAGTAGTGATGCAGCTTTGTGGACTTTGGGGTCATCCTGTTTTAGCAGTGAGAGTCTTATTTGAAATGAAAACTGCTAGGATAA
AGCCTAATGCTATTACTTATGGTTATTATAATAAGGTAGTCTTGGAGAGCCCGTGGCCTAGCAGTACCCGCAGTGGTATTTTCTTATGGA
CGAAGGTACGGAATGTGGTACGTGGCTTGGCACAGTTTAGGCAGCCGCTTAAAAAGACTGTGCAAAGGTCACAGGTCTCCTCAATATCAG
GTGGTCAGTCTGACCAAGGATACGGGTCTAAGGATGAACTTATAAAGGATGATGCAGAAATTCATGTGCCTGAAGAACAGGCAGCAAGAG
AATTGATAACTAAAACAAAAATGCAAACAGAAGAGGTGTGTGATGCCTCTGCTATTGTGGCAAAACATTCACAACCTAGTCCAGAGCCTC
ACAGTCCTACTGAACCTCCTGCATGGGGCAGCAGTATTGTGAAAGTTCCGTCTGGTATATTTGATGTCAACAGCAGGAAAAGTAGCACTG
GTAGTATATCAAATGTGCTGTTTTCTACTCAAGATCCAGTTGAAGATGCAGTCTTTGGCGAAGCTACTAATCTCAAGAAGAATGGTGATA
GAGGAGAAAAAAGACAAAAGCATTTTCCTGAGAGGAGTTGTAGTTTTAGTTCTGAAAGTCGAGCAGGAATGTTGCTTAAGAAGAGTAGTT
TGGATTCGAATTCAAGTGAAATGGCTATCATGATGGGAGCAGATGCCAAGATTCTCACAGCAGCATTGACATGTCCTAAGACTTCTCTAC
TTCATATTGCAAGAACCCATAGCTTTGAGAATGTTAGCTGTCACCTACCTGATAGTAGGACTTGTATGTCTGAAAGCACTTGGAATCCTG
AGCACAGATCATCTCCGGTGCCAGAGATGCTTGAGGAAAGCCAAGAACTCCTTGAGCCTGTGGTTGATGACGTACCTAAAACTACTGCAA
CAGTAGATACATATGAGAGTCTACTAAGTGATAGTAACAGTAATCAGTCCAGAGACTTGAAAACAGTATCCAAAGATCTGAGGAATAAGA
GAAGTAGTTTATATGGTATTGCTAAGGTGGTTCAGAGGGAAGATGTTGAAACTGGACTAGATCCTTTGTCTCTTTTAGCCACTGAATGTA
CAGGAGGAAAAACTCCTGATTCTGAAGATAAGTTGTTTTCTCCAGTTATTGCACGTAATCTGGCTGATGAAATAGAAAGCTATATGAACC
TAAAAAGTCCCCTAGGTAGTAAATCTTCTAGTATGGAATTACACAGAGAGGAAAACAGAGAGTCTGGCATGACTACTGCATTTATTCATG
CTCTAGAGAGGAGATCAAGCCTACCTTTAGATCATGGTTCACCAGCACAGGAAAATCCTGAAAGTGAAAAGAGCTCACCTGCAGTGTCCA
GGTCTAAAACTTTTACTGGGCGTTTCAAGCAGCAAACCCCCTCTCGAACTCATAAAGAACGTTCAACTTCTTTGTCAGCACTGGTGCGTT
CTTCGCCACATGGCTCGTTGGGTTCTGTAGTAAATTCTTTGTCAGGGCTAAAGCTGGATAATATACTCTCAGGGCCCAAGATAGATGTCC
TGAAATCTGGTATGAAACAAGCAGCGACAGTAGCCAGTAAGATGTGGGTAGCTGTTGCGTCTGCCTACAGCTACTCAGATGATGAGGAAG
AAACTAATAGAGACTACAGCTTCCCAGCTGGCCTAGAAGACCATATTTTGGGGGAGAATATATCGCCTAACACAAGTATCTCAGGGTTGG
TCCCCAGTGAACTTACCCAGAGCAACACAAGTCTTGGCAGTAGCAGCAGTAGTGGAGATGTAGGAAAACTGCATTATCCAACAGGTGAAG
TTCCATTTCCAAGAGGCATGAAAGGGCAAGACTTTGAAAAATCAGATCATGGTTCTTCTCAAAATACCAGCATGTCTAGCATCTATCAGA
ATTGTGCAATGGAGGTTTTGATGTCCAGTTGTTCACAGTGTAGAGCTTGTGGAGCTTTAGTTTATGATGAAGAAATTATGGCTGGATGGA
CAGCAGATGACTCAAATTTGAATACAGCTTGTCCATTCTGTAAAAGCAACTTCTTGCCTCTTCTCAATATAGAATTCAAAGATTTGAGAG
GTTCTGCAAGCTTTTTCCTGAAACCAAGTACCTCTGGTGACAGTTTACAAAGTGGAAGCATTCCATTGGCAAATGAATCCTTGGAGCACA
AACCTGTATCCAGTTTAGCAGAACCTGACTTGATCAACTTTATGGACTTCCCAAAACATAACCAGATCATAACTGAAGAAACAGGCTCTG
CAGTTGAACCAAGGTCCCGTTTAATGGATTCTGACATGGATTATGAAAGGCCAAACGTAGAGACCATCAAGTGCGTTGTGGTGGGGGACA
ACGCCGTGGGTAAGACCAGGCTCATCTGTGCCCGCGCTTGCAATGCCACCCTCACCCAGTACCAGCTGCTGGCCACGCATGTGCCCACAG
TATGGGCCATCGACCAATATCGTGTGTGCCAGGAGGTGCTGGAACGCTCCCGAGACGTGGTAGATGATGTCAGCGTCTCTCTGCGCCTCT
GGGACACCTTTGGAGACCACCACAAAGACCGTCGCTTTGCTTATGGGAGATCTGATGTGGTGGTTCTGTGCTTCTCCATTGCCAACCCCA
ATTCCCTCCACCATGTCAAGACCATGTGGTACCCAGAAATCAAGCACTTCTGCCCCCGAGCACCTGTCATCTTGGTGGGCTGCCAGTTGG
ACCTGCGCTACGCTGACCTGGAGGCTGTCAACAGGGCTAGGCGACCCTTGGCTAGGCCCATCAAACCTAATGAAATCCTGCCCCCAGAGA
AGGGTCGGGAGGTGGCCAAGGAGCTGGGCATCCCCTACTATGAGACCAGCGTGGTGGCCCAGTTCGGCATCAAGGACGTCTTTGACAACG
CCATCCGAGCTGCACTCATCTCCCGCCGCCACCTGCAGTTCTGGAAGTCCCACCTCCGCAATGTGCAGCGGCCTCTGCTGCAGGCACCCT
TCCTACCCCCCAAGCCACCGCCCCCGATCATCGTGGTGCCCGACCCTCCCTCCAGCAGCGAGGAGTGCCCCGCCCACCTCCTGGAGGACC
CGCTCTGCGCGGACGTCATCCTGGTGCTGCAGGAGCGGGTGCGCATCTTTGCCCACAAGATCTACCTCTCCACCTCTTCCTCCAAGTTCT
ATGACCTGTTCCTCATGGACCTGAGTGAGGGGGAGCTGGGGGGCCCCTCGGAGCCAGGGGGCACCCACCCAGAGGACCACCAGGGCCACT
CTGATCAACACCACCACCATCACCACCACCACCATGGGCGAGACTTCCTGCTCCGAGCAGCCAGCTTTGACGTGTGCGAGAGCGTGGATG
AGGCTGGGGGCTCCGGTCCTGCTGGCCTCCGTGCTTCCACCAGCGACGGGATCTTACGGGGCAACGGAACAGGGTACCTACCGGGCAGGG
GTCGTGTGCTGTCTTCCTGGAGCCGAGCTTTTGTGAGCATCCAGGAAGAGATGGCAGAAGATCCTCTCACCTACAAATCCCGGCTGATGG
TGGTGGTGAAGATGGACAGTTCCATCCAGCCGGGGCCCTTCCGGGCTGTCCTCAAGTACCTGTACACGGGGGAGCTAGATGAGAACGAGC
GTGACCTCATGCACATTGCCCACATTGCTGAGCTGCTCGAGGTCTTTGATCTGCGCATGATGGTGGCCAACATTCTCAACAATGAGGCCT
TCATGAACCAGGAGATCACCAAGGCCTTCCACGTCCGCCGGACCAACCGGGTTAAGGAGTGCTTGGCAAAAGGCACCTTCTCAGATGTGA
CCTTCATCCTGGATGATGGCACCATCAGCGCCCACAAGCCCCTGTTGATTTCCAGCTGTGACTGGATGGCTGCCATGTTTGGGGGGCCAT
TTGTGGAGAGCTCCACCCGGGAGGTGGTGTTTCCCTACACAAGCAAGAGCTGCATGCGGGCCGTGCTGGAATACCTCTACACCGGCATGT
TCACCTCCAGCCCCGACCTGGATGACATGAAGCTCATCATTCTAGCCAACCGCCTCTGCCTGCCACACCTGGTTGCCCTCACAGAGCAGT
ACACAGTGACCGGGCTGATGGAAGCGACCCAGATGATGGTGGACATCGATGGGGACGTCCTTGTGTTCCTGGAACTGGCTCAGTTCCACT
GTGCGTACCAGCTGGCCGACTGGTGTCTCCACCACATCTGCACCAACTACAACAACGTGTGCCGCAAGTTCCCCCGAGACATGAAGGCCA
TGTCCCCAGAAAACCAGGAGTATTTCGAGAAGCATCGGTGGCCACCTGTGTGGTACCTGAAGGAGGAAGATCATTACCAGCGGGCACGGA
AGGAGCGTGAGAAGGAGGACTACCTCCACCTCAAGCGGCAGCCCAAACGGCGTTGGCTCTTCTGGAACAGTCCATCCTCCCCGTCTTCCT
CGGCAGCCTCCTCCTCATCCCCATCTTCCTCCTCGGCTGTGGTCTGAGATGCTGCCACCCTCTTCTGACCCTGCTGCTGTTGTCCCCATC
CGCCTTCACCCCTCTGCTCTTCCGCATCACCCCATCCACCTTACAGGGACCAGGGGGCCCACGTAACCAGGACCCAGAGGGTGGAGCTCT
TCTTACCAGCCACCGTGGCTCAGCCAGAGAGGAGCTGAGCCCTGTGGAGCAGAACGGGAACCACCTGCAGAGGTCCCCAGACCCAAAGCA
GGACGGGAGACAACTGCTTGGAGGAGCGAAGAGCCCTGGCATTTTATCTCTGGGTTTGAGAGCCCTAGAGTCAAAGGGAAAGCCTCCCAG
CCTCCAGGGCTTCTCTGTGTGTCTTGGTTGCTGCTCTGGCCAGGGAGGCAGCCCCACTCCCAGCAAGCAGAAGTGATCCTCGAGGGTCCT
GCCCCTGTTGGCCATATCTTTCCACCGACGGACTTGAGTGTTGCATTTGTTTTGTGGGCATTTCCACACGAAGCCTACTCACACCCTCAC
TGGAGAAGTCAGGGTAGAAATTGAGCCTTCAGAGCCCAACTCAAGGCTTCTACATCCTGGGGTGCAGCTGCAAAAGGCCAGACGTGGAAA
GGCCTGTATCCTGCCAGTGTCCCTCCGTCCCAGGGGGCTGTGCTAGCACAGACCTGAGAATGGGGACACAGGTCATTCAGAGCTCCAGGC
CTGGAAGCAGTGCCTCTTGGTGCAACAAGAAACTTCTCCCTCACCCCCTCCTTTACCCTCAGATTTGGAGATGGTAACCAAAGGAAGCAG
CTGGGACAGGTGGAGAAGGAAGTAGGAATGAGTGCACGGCGACCCCGTGCTCCTCAGGGCCCTCCCCTGCCTCTGGGTGGCACTGCTTTT
TATAGGGTGGGGCAAAATTAGCAAAAAACAAAAACCAATGACAACCAAACTGAAACCGAAACGAAAAATCAACAAACACTCTGTCCTCTA

>22263_22263_9_DENND4C-RHOBTB2_DENND4C_chr9_19357152_ENST00000602925_RHOBTB2_chr8_22861937_ENST00000519685_length(amino acids)=2386AA_BP=1648
MRRRRPLELVPRPALPSAPSPRIRCFLAPGRSRVGAALTEEQAAENTVAAMIEDKGPRVTDYFVVAGLTDTSTLLDQEINRLDTKSTGPK
APITDIAIIIKSAGETVPEGYTCVEATPSALQANLNYGSLKSPELFLCYKRGRDKPPLTDIGVLYEGKERLIPGCEVILATPYGRCANVN
NSSTTSQRIFITYRRAPPVRPQNSLAVTDICVIVTSKGETPPHTFCKVDKNLNCGMWGSSVFLCYKKSVPASNAIAYKAGLIFRYPEEDY
ESFPLSESDVPLFCLPMGATIECWDPETKYPLPVFSTFVLTGSSAKKVYGAAIQFYEPYSRELLSEKQLMHLGLLTPVERKMVSKSINTN
KCICLLSHWPFFEAFRKFLMFIYKLSVSGPHPLPIEKHISHFMQNIPFPSPQRPRILVQLSVHDALILSQPVSTPLPLSGANFSTLLMNL
GPENCATLLLFVLLESKILLHSLRPAVLTGVAEAVVAMIFPFQWQCPYIPLCPLSLAAVLSAPLPFIVGVDSRYFDLHDPPQDVVCIDLD
TNMLYVSDEKKNMNWKQLPKKPCKNLLSTLKKLYPQLSSVHQKTQEGSAIDMTPIEADFSWQKKMTQLEMEIQEAFLRFMASILKGYRTY
LRPITEAPSNKATAADSLFDRQGFLKSRDRAYAKFYTLLSKTQIFIRFIEECSFVSDKDTGLAFFDDCIEKLFPDKGTEKTDKVDFDSAE
DTRLIELDDSQKSEHTVFIMPPEPPPDDGKDLSPKYSYKYFPRLDLKLFDRPQELKLCFSRHPTGNSITKSPPLMAKRTKQEIKTAHKLA
KRCYTNPPQWAKCLFSHCYSLWFICLPAYVRVSHPKVRALQQAYDVLIKMRKTDVDPLDEVCYRVVMQLCGLWGHPVLAVRVLFEMKTAR
IKPNAITYGYYNKVVLESPWPSSTRSGIFLWTKVRNVVRGLAQFRQPLKKTVQRSQVSSISGGQSDQGYGSKDELIKDDAEIHVPEEQAA
RELITKTKMQTEEVCDASAIVAKHSQPSPEPHSPTEPPAWGSSIVKVPSGIFDVNSRKSSTGSISNVLFSTQDPVEDAVFGEATNLKKNG
DRGEKRQKHFPERSCSFSSESRAGMLLKKSSLDSNSSEMAIMMGADAKILTAALTCPKTSLLHIARTHSFENVSCHLPDSRTCMSESTWN
PEHRSSPVPEMLEESQELLEPVVDDVPKTTATVDTYESLLSDSNSNQSRDLKTVSKDLRNKRSSLYGIAKVVQREDVETGLDPLSLLATE
CTGGKTPDSEDKLFSPVIARNLADEIESYMNLKSPLGSKSSSMELHREENRESGMTTAFIHALERRSSLPLDHGSPAQENPESEKSSPAV
SRSKTFTGRFKQQTPSRTHKERSTSLSALVRSSPHGSLGSVVNSLSGLKLDNILSGPKIDVLKSGMKQAATVASKMWVAVASAYSYSDDE
EETNRDYSFPAGLEDHILGENISPNTSISGLVPSELTQSNTSLGSSSSSGDVGKLHYPTGEVPFPRGMKGQDFEKSDHGSSQNTSMSSIY
QNCAMEVLMSSCSQCRACGALVYDEEIMAGWTADDSNLNTACPFCKSNFLPLLNIEFKDLRGSASFFLKPSTSGDSLQSGSIPLANESLE
HKPVSSLAEPDLINFMDFPKHNQIITEETGSAVEPRSRLMDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVP
TVWAIDQYRVCQEVLERSRDVVDDVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPRAPVILVGCQ
LDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKELGIPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQA
PFLPPKPPPPIIVVPDPPSSSEECPAHLLEDPLCADVILVLQERVRIFAHKIYLSTSSSKFYDLFLMDLSEGELGGPSEPGGTHPEDHQG
HSDQHHHHHHHHHGRDFLLRAASFDVCESVDEAGGSGPAGLRASTSDGILRGNGTGYLPGRGRVLSSWSRAFVSIQEEMAEDPLTYKSRL
MVVVKMDSSIQPGPFRAVLKYLYTGELDENERDLMHIAHIAELLEVFDLRMMVANILNNEAFMNQEITKAFHVRRTNRVKECLAKGTFSD
VTFILDDGTISAHKPLLISSCDWMAAMFGGPFVESSTREVVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIILANRLCLPHLVALTE
QYTVTGLMEATQMMVDIDGDVLVFLELAQFHCAYQLADWCLHHICTNYNNVCRKFPRDMKAMSPENQEYFEKHRWPPVWYLKEEDHYQRA

--------------------------------------------------------------
>22263_22263_10_DENND4C-RHOBTB2_DENND4C_chr9_19357152_ENST00000602925_RHOBTB2_chr8_22861937_ENST00000522948_length(transcript)=10150nt_BP=5233nt
GGAGGAAAGGGAGAGGGAGGGGGAAAAGAAAGTGCTGTTTTGTGGAAAGGGGCGGAAGGCGGGGGAGAAAAAGGGAACAGAAACATGGCG
GTCAGGTCTTGGGACGGCTGCGCCGCGGGCAGCTCCTAGGCGACGCGCCGCCCGCACTGTCCGACGGCTCACAGCGCGGAGGCACCCGCG
CGGGCCAGCGCTCCGGCCATCGCCCCTGGCTGTAGGCGGCGCCCCTCGGAGACCCTGCCCGCGAGGCGGCGCAGGCGCAGACCGGACTGA
GGCGGCGGCGGCCGCTGGAGCTAGTCCCCCGCCCTGCCCTGCCGAGCGCGCCCAGTCCGCGAATCCGGTGCTTTCTTGCCCCAGGAAGAA
GCCGTGTCGGGGCTGCGCTGACAGAGGAGCAGGCAGCAGAAAATACAGTAGCAGCCATGATAGAAGACAAAGGACCAAGAGTGACAGACT
ACTTTGTCGTAGCTGGTCTCACTGACACATCTACTCTTTTGGATCAAGAAATAAATCGTTTAGATACTAAGTCAACTGGACCTAAAGCTC
CAATTACAGACATTGCCATTATTATCAAATCAGCTGGAGAAACAGTACCTGAAGGTTACACCTGTGTAGAAGCCACTCCATCAGCTCTCC
AAGCAAACTTGAACTATGGAAGTCTGAAAAGCCCAGAACTTTTCCTCTGTTATAAGAGAGGGAGAGATAAACCACCGCTTACAGATATTG
GAGTTCTATATGAAGGGAAAGAACGGCTTATTCCAGGATGTGAAGTGATCCTAGCCACACCCTATGGTCGCTGTGCCAATGTCAACAATA
GTTCAACTACTTCACAAAGAATCTTTATCACTTATCGAAGGGCTCCTCCAGTTCGACCCCAGAATTCCTTGGCTGTAACTGATATCTGTG
TTATTGTAACCAGTAAAGGAGAAACTCCTCCTCATACCTTCTGCAAAGTTGACAAAAACTTAAATTGTGGAATGTGGGGTTCCAGCGTGT
TTCTGTGTTATAAGAAGTCTGTACCTGCTTCAAATGCAATAGCATATAAGGCTGGTTTAATTTTTAGATATCCAGAAGAGGACTATGAGT
CATTTCCACTCTCAGAATCAGATGTACCTCTTTTCTGCCTTCCTATGGGAGCTACTATTGAGTGCTGGGATCCTGAAACCAAATATCCAC
TTCCAGTTTTTTCAACTTTTGTCTTGACAGGTTCTTCAGCCAAAAAGGTATATGGAGCTGCCATTCAGTTTTATGAACCTTACTCTCGGG
AACTTCTATCAGAGAAACAGCTTATGCACCTGGGCTTGTTGACGCCTGTGGAGAGAAAAATGGTCTCCAAATCCATCAATACAAACAAAT
GCATTTGTTTACTCTCACACTGGCCTTTTTTTGAAGCTTTTAGGAAATTTCTTATGTTTATCTACAAACTTTCTGTGTCTGGACCACATC
CTCTTCCCATTGAAAAGCACATTTCACATTTTATGCAAAACATCCCTTTTCCTTCACCACAAAGACCGAGAATCCTTGTCCAGCTGTCAG
TCCATGATGCATTAATATTATCACAGCCAGTTTCTACACCTTTACCACTAAGTGGAGCCAACTTTAGCACCTTGCTAATGAATCTGGGTC
CTGAGAATTGTGCAACACTGCTGCTCTTTGTTTTACTTGAGAGTAAAATTCTGCTGCATTCTCTTAGGCCAGCTGTCTTGACTGGGGTAG
CTGAAGCTGTTGTAGCTATGATCTTTCCATTTCAGTGGCAATGCCCATATATTCCCCTTTGTCCTCTTTCACTGGCTGCAGTGCTTAGTG
CACCTTTACCATTTATAGTTGGAGTTGACTCAAGGTATTTTGATCTTCATGACCCACCACAAGATGTTGTTTGCATTGACTTGGATACGA
ACATGTTATATGTATCAGATGAAAAGAAGAACATGAACTGGAAGCAACTTCCCAAAAAGCCGTGCAAAAATCTACTTAGCACCTTAAAGA
AATTGTATCCCCAGCTGTCTTCAGTTCACCAAAAAACTCAAGAAGGCTCAGCGATTGACATGACTCCAATTGAAGCAGATTTCTCCTGGC
AAAAGAAGATGACACAGCTTGAGATGGAAATTCAAGAGGCATTTTTGCGCTTTATGGCGTCTATTTTAAAAGGATATAGAACATATCTCA
GACCAATCACAGAGGCTCCTTCAAATAAAGCCACAGCTGCTGATTCATTGTTTGACCGACAGGGATTTTTAAAAAGTCGAGATCGTGCCT
ATGCAAAATTCTATACCCTTTTATCCAAAACACAGATTTTTATTCGTTTCATTGAAGAATGCAGTTTTGTAAGTGATAAAGATACTGGAT
TAGCATTTTTTGATGACTGCATAGAAAAGTTGTTTCCTGATAAAGGCACAGAGAAAACAGATAAGGTTGATTTTGATTCAGCAGAAGATA
CCAGATTGATAGAACTAGATGATTCACAGAAAAGTGAGCATACTGTATTTATAATGCCGCCAGAGCCACCTCCTGATGATGGAAAGGACC
TGTCACCAAAGTACAGTTACAAATACTTTCCAAGACTGGACCTTAAGCTTTTTGACAGACCGCAGGAGTTGAAACTTTGTTTTAGTAGAC
ACCCTACTGGGAATAGCATTACAAAGAGTCCACCTCTCATGGCTAAGAGAACTAAACAGGAAATAAAAACAGCTCATAAATTGGCGAAGA
GATGTTATACAAATCCACCACAGTGGGCCAAGTGTCTGTTTAGTCATTGTTACAGTTTATGGTTTATTTGTCTTCCGGCCTATGTTAGAG
TTTCTCATCCTAAAGTCAGAGCACTTCAGCAGGCATATGATGTACTTATTAAGATGAGGAAAACAGATGTGGATCCCTTAGATGAGGTGT
GCTATCGAGTAGTGATGCAGCTTTGTGGACTTTGGGGTCATCCTGTTTTAGCAGTGAGAGTCTTATTTGAAATGAAAACTGCTAGGATAA
AGCCTAATGCTATTACTTATGGTTATTATAATAAGGTAGTCTTGGAGAGCCCGTGGCCTAGCAGTACCCGCAGTGGTATTTTCTTATGGA
CGAAGGTACGGAATGTGGTACGTGGCTTGGCACAGTTTAGGCAGCCGCTTAAAAAGACTGTGCAAAGGTCACAGGTCTCCTCAATATCAG
GTGGTCAGTCTGACCAAGGATACGGGTCTAAGGATGAACTTATAAAGGATGATGCAGAAATTCATGTGCCTGAAGAACAGGCAGCAAGAG
AATTGATAACTAAAACAAAAATGCAAACAGAAGAGGTGTGTGATGCCTCTGCTATTGTGGCAAAACATTCACAACCTAGTCCAGAGCCTC
ACAGTCCTACTGAACCTCCTGCATGGGGCAGCAGTATTGTGAAAGTTCCGTCTGGTATATTTGATGTCAACAGCAGGAAAAGTAGCACTG
GTAGTATATCAAATGTGCTGTTTTCTACTCAAGATCCAGTTGAAGATGCAGTCTTTGGCGAAGCTACTAATCTCAAGAAGAATGGTGATA
GAGGAGAAAAAAGACAAAAGCATTTTCCTGAGAGGAGTTGTAGTTTTAGTTCTGAAAGTCGAGCAGGAATGTTGCTTAAGAAGAGTAGTT
TGGATTCGAATTCAAGTGAAATGGCTATCATGATGGGAGCAGATGCCAAGATTCTCACAGCAGCATTGACATGTCCTAAGACTTCTCTAC
TTCATATTGCAAGAACCCATAGCTTTGAGAATGTTAGCTGTCACCTACCTGATAGTAGGACTTGTATGTCTGAAAGCACTTGGAATCCTG
AGCACAGATCATCTCCGGTGCCAGAGATGCTTGAGGAAAGCCAAGAACTCCTTGAGCCTGTGGTTGATGACGTACCTAAAACTACTGCAA
CAGTAGATACATATGAGAGTCTACTAAGTGATAGTAACAGTAATCAGTCCAGAGACTTGAAAACAGTATCCAAAGATCTGAGGAATAAGA
GAAGTAGTTTATATGGTATTGCTAAGGTGGTTCAGAGGGAAGATGTTGAAACTGGACTAGATCCTTTGTCTCTTTTAGCCACTGAATGTA
CAGGAGGAAAAACTCCTGATTCTGAAGATAAGTTGTTTTCTCCAGTTATTGCACGTAATCTGGCTGATGAAATAGAAAGCTATATGAACC
TAAAAAGTCCCCTAGGTAGTAAATCTTCTAGTATGGAATTACACAGAGAGGAAAACAGAGAGTCTGGCATGACTACTGCATTTATTCATG
CTCTAGAGAGGAGATCAAGCCTACCTTTAGATCATGGTTCACCAGCACAGGAAAATCCTGAAAGTGAAAAGAGCTCACCTGCAGTGTCCA
GGTCTAAAACTTTTACTGGGCGTTTCAAGCAGCAAACCCCCTCTCGAACTCATAAAGAACGTTCAACTTCTTTGTCAGCACTGGTGCGTT
CTTCGCCACATGGCTCGTTGGGTTCTGTAGTAAATTCTTTGTCAGGGCTAAAGCTGGATAATATACTCTCAGGGCCCAAGATAGATGTCC
TGAAATCTGGTATGAAACAAGCAGCGACAGTAGCCAGTAAGATGTGGGTAGCTGTTGCGTCTGCCTACAGCTACTCAGATGATGAGGAAG
AAACTAATAGAGACTACAGCTTCCCAGCTGGCCTAGAAGACCATATTTTGGGGGAGAATATATCGCCTAACACAAGTATCTCAGGGTTGG
TCCCCAGTGAACTTACCCAGAGCAACACAAGTCTTGGCAGTAGCAGCAGTAGTGGAGATGTAGGAAAACTGCATTATCCAACAGGTGAAG
TTCCATTTCCAAGAGGCATGAAAGGGCAAGACTTTGAAAAATCAGATCATGGTTCTTCTCAAAATACCAGCATGTCTAGCATCTATCAGA
ATTGTGCAATGGAGGTTTTGATGTCCAGTTGTTCACAGTGTAGAGCTTGTGGAGCTTTAGTTTATGATGAAGAAATTATGGCTGGATGGA
CAGCAGATGACTCAAATTTGAATACAGCTTGTCCATTCTGTAAAAGCAACTTCTTGCCTCTTCTCAATATAGAATTCAAAGATTTGAGAG
GTTCTGCAAGCTTTTTCCTGAAACCAAGTACCTCTGGTGACAGTTTACAAAGTGGAAGCATTCCATTGGCAAATGAATCCTTGGAGCACA
AACCTGTATCCAGTTTAGCAGAACCTGACTTGATCAACTTTATGGACTTCCCAAAACATAACCAGATCATAACTGAAGAAACAGGCTCTG
CAGTTGAACCAAGGTCCCGTTTAATGGATTCTGACATGGATTATGAAAGGCCAAACGTAGAGACCATCAAGTGCGTTGTGGTGGGGGACA
ACGCCGTGGGTAAGACCAGGCTCATCTGTGCCCGCGCTTGCAATGCCACCCTCACCCAGTACCAGCTGCTGGCCACGCATGTGCCCACAG
TATGGGCCATCGACCAATATCGTGTGTGCCAGGAGGTGCTGGAACGCTCCCGAGACGTGGTAGATGATGTCAGCGTCTCTCTGCGCCTCT
GGGACACCTTTGGAGACCACCACAAAGACCGTCGCTTTGCTTATGGGAGATCTGATGTGGTGGTTCTGTGCTTCTCCATTGCCAACCCCA
ATTCCCTCCACCATGTCAAGACCATGTGGTACCCAGAAATCAAGCACTTCTGCCCCCGAGCACCTGTCATCTTGGTGGGCTGCCAGTTGG
ACCTGCGCTACGCTGACCTGGAGGCTGTCAACAGGGCTAGGCGACCCTTGGCTAGGCCCATCAAACCTAATGAAATCCTGCCCCCAGAGA
AGGGTCGGGAGGTGGCCAAGGAGCTGGGCATCCCCTACTATGAGACCAGCGTGGTGGCCCAGTTCGGCATCAAGGACGTCTTTGACAACG
CCATCCGAGCTGCACTCATCTCCCGCCGCCACCTGCAGTTCTGGAAGTCCCACCTCCGCAATGTGCAGCGGCCTCTGCTGCAGGCACCCT
TCCTACCCCCCAAGCCACCGCCCCCGATCATCGTGGTGCCCGACCCTCCCTCCAGCAGCGAGGAGTGCCCCGCCCACCTCCTGGAGGACC
CGCTCTGCGCGGACGTCATCCTGGTGCTGCAGGAGCGGGTGCGCATCTTTGCCCACAAGATCTACCTCTCCACCTCTTCCTCCAAGTTCT
ATGACCTGTTCCTCATGGACCTGAGTGAGGGGGAGCTGGGGGGCCCCTCGGAGCCAGGGGGCACCCACCCAGAGGACCACCAGGGCCACT
CTGATCAACACCACCACCATCACCACCACCACCATGGGCGAGACTTCCTGCTCCGAGCAGCCAGCTTTGACGTGTGCGAGAGCGTGGATG
AGGCTGGGGGCTCCGGTCCTGCTGGCCTCCGTGCTTCCACCAGCGACGGGATCTTACGGGGCAACGGAACAGGGTACCTACCGGGCAGGG
GTCGTGTGCTGTCTTCCTGGAGCCGAGCTTTTGTGAGCATCCAGGAAGAGATGGCAGAAGATCCTCTCACCTACAAATCCCGGCTGATGG
TGGTGGTGAAGATGGACAGTTCCATCCAGCCGGGGCCCTTCCGGGCTGTCCTCAAGTACCTGTACACGGGGGAGCTAGATGAGAACGAGC
GTGACCTCATGCACATTGCCCACATTGCTGAGCTGCTCGAGGTCTTTGATCTGCGCATGATGGTGGCCAACATTCTCAACAATGAGGCCT
TCATGAACCAGGAGATCACCAAGGCCTTCCACGTCCGCCGGACCAACCGGGTTAAGGAGTGCTTGGCAAAAGGCACCTTCTCAGATGTGA
CCTTCATCCTGGATGATGGCACCATCAGCGCCCACAAGCCCCTGTTGATTTCCAGCTGTGACTGGATGGCTGCCATGTTTGGGGGGCCAT
TTGTGGAGAGCTCCACCCGGGAGGTGGTGTTTCCCTACACAAGCAAGAGCTGCATGCGGGCCGTGCTGGAATACCTCTACACCGGCATGT
TCACCTCCAGCCCCGACCTGGATGACATGAAGCTCATCATTCTAGCCAACCGCCTCTGCCTGCCACACCTGGTTGCCCTCACAGAGCAGT
ACACAGTGACCGGGCTGATGGAAGCGACCCAGATGATGGTGGACATCGATGGGGACGTCCTTGTGTTCCTGGAACTGGCTCAGTTCCACT
GTGCGTACCAGCTGGCCGACTGGTGTCTCCACCACATCTGCACCAACTACAACAACGTGTGCCGCAAGTTCCCCCGAGACATGAAGGCCA
TGTCCCCAGAAAACCAGGAGTATTTCGAGAAGCATCGGTGGCCACCTGTGTGGTACCTGAAGGAGGAAGATCATTACCAGCGGGCACGGA
AGGAGCGTGAGAAGGAGGACTACCTCCACCTCAAGCGGCAGCCCAAACGGCGTTGGCTCTTCTGGAACAGTCCATCCTCCCCGTCTTCCT
CGGCAGCCTCCTCCTCATCCCCATCTTCCTCCTCGGCTGTGGTCTGAGATGCTGCCACCCTCTTCTGACCCTGCTGCTGTTGTCCCCATC
CGCCTTCACCCCTCTGCTCTTCCGCATCACCCCATCCACCTTACAGGGACCAGGGGGCCCACGTAACCAGGACCCAGAGGGTGGAGCTCT
TCTTACCAGCCACCGTGGCTCAGCCAGAGAGGAGCTGAGCCCTGTGGAGCAGAACGGGAACCACCTGCAGAGGTCCCCAGACCCAAAGCA
GGACGGGAGACAACTGCTTGGAGGAGCGAAGAGCCCTGGCATTTTATCTCTGGGTTTGAGAGCCCTAGAGTCAAAGGGAAAGCCTCCCAG
CCTCCAGGGCTTCTCTGTGTGTCTTGGTTGCTGCTCTGGCCAGGGAGGCAGCCCCACTCCCAGCAAGCAGAAGTGATCCTCGAGGGTCCT
GCCCCTGTTGGCCATATCTTTCCACCGACGGACTTGAGTGTTGCATTTGTTTTGTGGGCATTTCCACACGAAGCCTACTCACACCCTCAC
TGGAGAAGTCAGGGTAGAAATTGAGCCTTCAGAGCCCAACTCAAGGCTTCTACATCCTGGGGTGCAGCTGCAAAAGGCCAGACGTGGAAA
GGCCTGTATCCTGCCAGTGTCCCTCCGTCCCAGGGGGCTGTGCTAGCACAGACCTGAGAATGGGGACACAGGTCATTCAGAGCTCCAGGC
CTGGAAGCAGTGCCTCTTGGTGCAACAAGAAACTTCTCCCTCACCCCCTCCTTTACCCTCAGATTTGGAGATGGTAACCAAAGGAAGCAG
CTGGGACAGGTGGAGAAGGAAGTAGGAATGAGTGCACGGCGACCCCGTGCTCCTCAGGGCCCTCCCCTGCCTCTGGGTGGCACTGCTTTT
TATAGGGTGGGGCAAAATTAGCAAAAAACAAAAACCAATGACAACCAAACTGAAACCGAAACGAAAAATCAACAAACACTCTGTCCTCTA
TCCCTCCAAAGAATGAAAATCAGAAAAAGCCCCTGCCTAGCTCACATTTCTATAAACAGAGGCCCCCATGATGAGGAGGTGAAGATTTAG
GTTGCAGAATCGACTCCAATGCCTTTCAGGAAAGGACTCGGCACTTCTCTGACTGCGGAGGCCCTGACCCTGCCAGCTGGCTCCGAGGGC
AACACAGGGGCCTGGCCTCTAGAGGGCTGGTGATTGAGGGGCCCGGGCTGGCGGCAAAGAGGGGTTTGGTCTCGGGGCTTAAATGGCACC
AGACTCTTGCTTTTGCCCATCTGGAGACTGCAGGCTCCCTTCCTTACCCTCAGAGAGTGCTTATGGTGGGTGTTTTTGCGGGGCTGCAAT
AGGGGCCAAAAGTCAGGGAAAGGGGCACTGACCTGTAGTGAAAGGCCACAGGACACAGCCTTATTACTGCTGGGGTGGGATAAGGGGAAG
GAGAAGAGGGAGAATGGAGCAGGAGGAAAAGCAGAGTTGGTCTAGAGAGGAGGAGGGCGGGGCTGGAGGAATGTGGGGGATTGAAACTAG
CTCCCAGCCCCCATGGGGCAGCAGCTGGGCCACAATTGCCCCTTTCCGTTTTCTAACCCCGACTCAGATTTCACCACCCACACTCTTTTT
AGGTGTAAAAGATGGAGTCCCACGGAGGAGGGGCAGAGCCAGGAGGCAGTGGGGCTGTGGGCTCAGAGCTCAGGAGTCGCCTTACCTGAG
AGAGATGTTCTAGCTGAGAGGGCCTGGCCCTGGGGTGGGCTCCAGGAAAACGCTGGTTAGGCCTGGGATTGAGCTAACCTGAAACAAAGG
TAGCAGGCAGGACCTAATGACCAGAGGTTAAATCCTCATCAAGAGAGACCAGGCGGCTGGAGGACAAGCGGCTCTAACCCTGGGGGCGGC
CATGTTGTCCAGGCCCAGGCCCCTCCAGGACTGTGGCTGCCTCCCCTCCACGGCCTCCAGGGCGGCTGGCTGGAAAGCCACGCGTATGCT
GCCCTCTACAGGCTGCTCGGCCTCCCTGCAGCTCAGCGCAGCCCAGGGCTCCAAGTGAGGCCCAGAAGCCCATGGGCAGGGCTGGGGGGA
CGAAGGGGGAACCCGGAGCACCTCCACTTCTAGGGAAGATGGACAGCGTGGGGGCACACCTGGGCCTCCCGGAAGCTGTGGACGAAAGGG
AGAGCGGGTCCTCCAGGGCAAGGGGAACGGGAAATAGGTCTCCTAGGTGCCTGAAGCGCTGAGCAACCTGGGTACCCTGGTGGGGATGCA
GGGAAGGCCGGGGCAGAGAAAGTGAAGGTCGACCCAGGGCTGTAGGAAGCCATAGGAGAGTGACCACGGGATTCCCTGAGAAACAGGGCC
GGCCCCCCAACTTCAGGGACCCACCGCCCATTCCCCGAGAGCTGTCGGAACCAGATGCAACCCGGCAGCCCAGAGAACTCTCCTGGGAGG
CTGTGGGTGAGCCAGGCCAACATTGGTGTCCCTGTCCCCAGAGGGAGGAGCAGGCAGGAGAGAGAGGGGAAGGAGGTATGAATCCCAGTC
CCCAGGAACCTAGCTCTTTAAACTCTGGGGAGTCGGATTCAGGAAACACCCCCAGGAGGCCAAGCCTGAAAACAGAGGGGAGGGAGGAAG
GAAGGAGTCCCAGCAGGAGCACAGCCCTGGTTTCCTGTCACTCAGAGCTGATTCACAGGAGGAGGGGAGGTTGGGGGGCGGGAGACAAAA

>22263_22263_10_DENND4C-RHOBTB2_DENND4C_chr9_19357152_ENST00000602925_RHOBTB2_chr8_22861937_ENST00000522948_length(amino acids)=2386AA_BP=1648
MRRRRPLELVPRPALPSAPSPRIRCFLAPGRSRVGAALTEEQAAENTVAAMIEDKGPRVTDYFVVAGLTDTSTLLDQEINRLDTKSTGPK
APITDIAIIIKSAGETVPEGYTCVEATPSALQANLNYGSLKSPELFLCYKRGRDKPPLTDIGVLYEGKERLIPGCEVILATPYGRCANVN
NSSTTSQRIFITYRRAPPVRPQNSLAVTDICVIVTSKGETPPHTFCKVDKNLNCGMWGSSVFLCYKKSVPASNAIAYKAGLIFRYPEEDY
ESFPLSESDVPLFCLPMGATIECWDPETKYPLPVFSTFVLTGSSAKKVYGAAIQFYEPYSRELLSEKQLMHLGLLTPVERKMVSKSINTN
KCICLLSHWPFFEAFRKFLMFIYKLSVSGPHPLPIEKHISHFMQNIPFPSPQRPRILVQLSVHDALILSQPVSTPLPLSGANFSTLLMNL
GPENCATLLLFVLLESKILLHSLRPAVLTGVAEAVVAMIFPFQWQCPYIPLCPLSLAAVLSAPLPFIVGVDSRYFDLHDPPQDVVCIDLD
TNMLYVSDEKKNMNWKQLPKKPCKNLLSTLKKLYPQLSSVHQKTQEGSAIDMTPIEADFSWQKKMTQLEMEIQEAFLRFMASILKGYRTY
LRPITEAPSNKATAADSLFDRQGFLKSRDRAYAKFYTLLSKTQIFIRFIEECSFVSDKDTGLAFFDDCIEKLFPDKGTEKTDKVDFDSAE
DTRLIELDDSQKSEHTVFIMPPEPPPDDGKDLSPKYSYKYFPRLDLKLFDRPQELKLCFSRHPTGNSITKSPPLMAKRTKQEIKTAHKLA
KRCYTNPPQWAKCLFSHCYSLWFICLPAYVRVSHPKVRALQQAYDVLIKMRKTDVDPLDEVCYRVVMQLCGLWGHPVLAVRVLFEMKTAR
IKPNAITYGYYNKVVLESPWPSSTRSGIFLWTKVRNVVRGLAQFRQPLKKTVQRSQVSSISGGQSDQGYGSKDELIKDDAEIHVPEEQAA
RELITKTKMQTEEVCDASAIVAKHSQPSPEPHSPTEPPAWGSSIVKVPSGIFDVNSRKSSTGSISNVLFSTQDPVEDAVFGEATNLKKNG
DRGEKRQKHFPERSCSFSSESRAGMLLKKSSLDSNSSEMAIMMGADAKILTAALTCPKTSLLHIARTHSFENVSCHLPDSRTCMSESTWN
PEHRSSPVPEMLEESQELLEPVVDDVPKTTATVDTYESLLSDSNSNQSRDLKTVSKDLRNKRSSLYGIAKVVQREDVETGLDPLSLLATE
CTGGKTPDSEDKLFSPVIARNLADEIESYMNLKSPLGSKSSSMELHREENRESGMTTAFIHALERRSSLPLDHGSPAQENPESEKSSPAV
SRSKTFTGRFKQQTPSRTHKERSTSLSALVRSSPHGSLGSVVNSLSGLKLDNILSGPKIDVLKSGMKQAATVASKMWVAVASAYSYSDDE
EETNRDYSFPAGLEDHILGENISPNTSISGLVPSELTQSNTSLGSSSSSGDVGKLHYPTGEVPFPRGMKGQDFEKSDHGSSQNTSMSSIY
QNCAMEVLMSSCSQCRACGALVYDEEIMAGWTADDSNLNTACPFCKSNFLPLLNIEFKDLRGSASFFLKPSTSGDSLQSGSIPLANESLE
HKPVSSLAEPDLINFMDFPKHNQIITEETGSAVEPRSRLMDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVP
TVWAIDQYRVCQEVLERSRDVVDDVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPRAPVILVGCQ
LDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKELGIPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQA
PFLPPKPPPPIIVVPDPPSSSEECPAHLLEDPLCADVILVLQERVRIFAHKIYLSTSSSKFYDLFLMDLSEGELGGPSEPGGTHPEDHQG
HSDQHHHHHHHHHGRDFLLRAASFDVCESVDEAGGSGPAGLRASTSDGILRGNGTGYLPGRGRVLSSWSRAFVSIQEEMAEDPLTYKSRL
MVVVKMDSSIQPGPFRAVLKYLYTGELDENERDLMHIAHIAELLEVFDLRMMVANILNNEAFMNQEITKAFHVRRTNRVKECLAKGTFSD
VTFILDDGTISAHKPLLISSCDWMAAMFGGPFVESSTREVVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIILANRLCLPHLVALTE
QYTVTGLMEATQMMVDIDGDVLVFLELAQFHCAYQLADWCLHHICTNYNNVCRKFPRDMKAMSPENQEYFEKHRWPPVWYLKEEDHYQRA

--------------------------------------------------------------
>22263_22263_11_DENND4C-RHOBTB2_DENND4C_chr9_19357152_ENST00000602925_RHOBTB2_chr8_22861938_ENST00000519685_length(transcript)=8399nt_BP=5233nt
GGAGGAAAGGGAGAGGGAGGGGGAAAAGAAAGTGCTGTTTTGTGGAAAGGGGCGGAAGGCGGGGGAGAAAAAGGGAACAGAAACATGGCG
GTCAGGTCTTGGGACGGCTGCGCCGCGGGCAGCTCCTAGGCGACGCGCCGCCCGCACTGTCCGACGGCTCACAGCGCGGAGGCACCCGCG
CGGGCCAGCGCTCCGGCCATCGCCCCTGGCTGTAGGCGGCGCCCCTCGGAGACCCTGCCCGCGAGGCGGCGCAGGCGCAGACCGGACTGA
GGCGGCGGCGGCCGCTGGAGCTAGTCCCCCGCCCTGCCCTGCCGAGCGCGCCCAGTCCGCGAATCCGGTGCTTTCTTGCCCCAGGAAGAA
GCCGTGTCGGGGCTGCGCTGACAGAGGAGCAGGCAGCAGAAAATACAGTAGCAGCCATGATAGAAGACAAAGGACCAAGAGTGACAGACT
ACTTTGTCGTAGCTGGTCTCACTGACACATCTACTCTTTTGGATCAAGAAATAAATCGTTTAGATACTAAGTCAACTGGACCTAAAGCTC
CAATTACAGACATTGCCATTATTATCAAATCAGCTGGAGAAACAGTACCTGAAGGTTACACCTGTGTAGAAGCCACTCCATCAGCTCTCC
AAGCAAACTTGAACTATGGAAGTCTGAAAAGCCCAGAACTTTTCCTCTGTTATAAGAGAGGGAGAGATAAACCACCGCTTACAGATATTG
GAGTTCTATATGAAGGGAAAGAACGGCTTATTCCAGGATGTGAAGTGATCCTAGCCACACCCTATGGTCGCTGTGCCAATGTCAACAATA
GTTCAACTACTTCACAAAGAATCTTTATCACTTATCGAAGGGCTCCTCCAGTTCGACCCCAGAATTCCTTGGCTGTAACTGATATCTGTG
TTATTGTAACCAGTAAAGGAGAAACTCCTCCTCATACCTTCTGCAAAGTTGACAAAAACTTAAATTGTGGAATGTGGGGTTCCAGCGTGT
TTCTGTGTTATAAGAAGTCTGTACCTGCTTCAAATGCAATAGCATATAAGGCTGGTTTAATTTTTAGATATCCAGAAGAGGACTATGAGT
CATTTCCACTCTCAGAATCAGATGTACCTCTTTTCTGCCTTCCTATGGGAGCTACTATTGAGTGCTGGGATCCTGAAACCAAATATCCAC
TTCCAGTTTTTTCAACTTTTGTCTTGACAGGTTCTTCAGCCAAAAAGGTATATGGAGCTGCCATTCAGTTTTATGAACCTTACTCTCGGG
AACTTCTATCAGAGAAACAGCTTATGCACCTGGGCTTGTTGACGCCTGTGGAGAGAAAAATGGTCTCCAAATCCATCAATACAAACAAAT
GCATTTGTTTACTCTCACACTGGCCTTTTTTTGAAGCTTTTAGGAAATTTCTTATGTTTATCTACAAACTTTCTGTGTCTGGACCACATC
CTCTTCCCATTGAAAAGCACATTTCACATTTTATGCAAAACATCCCTTTTCCTTCACCACAAAGACCGAGAATCCTTGTCCAGCTGTCAG
TCCATGATGCATTAATATTATCACAGCCAGTTTCTACACCTTTACCACTAAGTGGAGCCAACTTTAGCACCTTGCTAATGAATCTGGGTC
CTGAGAATTGTGCAACACTGCTGCTCTTTGTTTTACTTGAGAGTAAAATTCTGCTGCATTCTCTTAGGCCAGCTGTCTTGACTGGGGTAG
CTGAAGCTGTTGTAGCTATGATCTTTCCATTTCAGTGGCAATGCCCATATATTCCCCTTTGTCCTCTTTCACTGGCTGCAGTGCTTAGTG
CACCTTTACCATTTATAGTTGGAGTTGACTCAAGGTATTTTGATCTTCATGACCCACCACAAGATGTTGTTTGCATTGACTTGGATACGA
ACATGTTATATGTATCAGATGAAAAGAAGAACATGAACTGGAAGCAACTTCCCAAAAAGCCGTGCAAAAATCTACTTAGCACCTTAAAGA
AATTGTATCCCCAGCTGTCTTCAGTTCACCAAAAAACTCAAGAAGGCTCAGCGATTGACATGACTCCAATTGAAGCAGATTTCTCCTGGC
AAAAGAAGATGACACAGCTTGAGATGGAAATTCAAGAGGCATTTTTGCGCTTTATGGCGTCTATTTTAAAAGGATATAGAACATATCTCA
GACCAATCACAGAGGCTCCTTCAAATAAAGCCACAGCTGCTGATTCATTGTTTGACCGACAGGGATTTTTAAAAAGTCGAGATCGTGCCT
ATGCAAAATTCTATACCCTTTTATCCAAAACACAGATTTTTATTCGTTTCATTGAAGAATGCAGTTTTGTAAGTGATAAAGATACTGGAT
TAGCATTTTTTGATGACTGCATAGAAAAGTTGTTTCCTGATAAAGGCACAGAGAAAACAGATAAGGTTGATTTTGATTCAGCAGAAGATA
CCAGATTGATAGAACTAGATGATTCACAGAAAAGTGAGCATACTGTATTTATAATGCCGCCAGAGCCACCTCCTGATGATGGAAAGGACC
TGTCACCAAAGTACAGTTACAAATACTTTCCAAGACTGGACCTTAAGCTTTTTGACAGACCGCAGGAGTTGAAACTTTGTTTTAGTAGAC
ACCCTACTGGGAATAGCATTACAAAGAGTCCACCTCTCATGGCTAAGAGAACTAAACAGGAAATAAAAACAGCTCATAAATTGGCGAAGA
GATGTTATACAAATCCACCACAGTGGGCCAAGTGTCTGTTTAGTCATTGTTACAGTTTATGGTTTATTTGTCTTCCGGCCTATGTTAGAG
TTTCTCATCCTAAAGTCAGAGCACTTCAGCAGGCATATGATGTACTTATTAAGATGAGGAAAACAGATGTGGATCCCTTAGATGAGGTGT
GCTATCGAGTAGTGATGCAGCTTTGTGGACTTTGGGGTCATCCTGTTTTAGCAGTGAGAGTCTTATTTGAAATGAAAACTGCTAGGATAA
AGCCTAATGCTATTACTTATGGTTATTATAATAAGGTAGTCTTGGAGAGCCCGTGGCCTAGCAGTACCCGCAGTGGTATTTTCTTATGGA
CGAAGGTACGGAATGTGGTACGTGGCTTGGCACAGTTTAGGCAGCCGCTTAAAAAGACTGTGCAAAGGTCACAGGTCTCCTCAATATCAG
GTGGTCAGTCTGACCAAGGATACGGGTCTAAGGATGAACTTATAAAGGATGATGCAGAAATTCATGTGCCTGAAGAACAGGCAGCAAGAG
AATTGATAACTAAAACAAAAATGCAAACAGAAGAGGTGTGTGATGCCTCTGCTATTGTGGCAAAACATTCACAACCTAGTCCAGAGCCTC
ACAGTCCTACTGAACCTCCTGCATGGGGCAGCAGTATTGTGAAAGTTCCGTCTGGTATATTTGATGTCAACAGCAGGAAAAGTAGCACTG
GTAGTATATCAAATGTGCTGTTTTCTACTCAAGATCCAGTTGAAGATGCAGTCTTTGGCGAAGCTACTAATCTCAAGAAGAATGGTGATA
GAGGAGAAAAAAGACAAAAGCATTTTCCTGAGAGGAGTTGTAGTTTTAGTTCTGAAAGTCGAGCAGGAATGTTGCTTAAGAAGAGTAGTT
TGGATTCGAATTCAAGTGAAATGGCTATCATGATGGGAGCAGATGCCAAGATTCTCACAGCAGCATTGACATGTCCTAAGACTTCTCTAC
TTCATATTGCAAGAACCCATAGCTTTGAGAATGTTAGCTGTCACCTACCTGATAGTAGGACTTGTATGTCTGAAAGCACTTGGAATCCTG
AGCACAGATCATCTCCGGTGCCAGAGATGCTTGAGGAAAGCCAAGAACTCCTTGAGCCTGTGGTTGATGACGTACCTAAAACTACTGCAA
CAGTAGATACATATGAGAGTCTACTAAGTGATAGTAACAGTAATCAGTCCAGAGACTTGAAAACAGTATCCAAAGATCTGAGGAATAAGA
GAAGTAGTTTATATGGTATTGCTAAGGTGGTTCAGAGGGAAGATGTTGAAACTGGACTAGATCCTTTGTCTCTTTTAGCCACTGAATGTA
CAGGAGGAAAAACTCCTGATTCTGAAGATAAGTTGTTTTCTCCAGTTATTGCACGTAATCTGGCTGATGAAATAGAAAGCTATATGAACC
TAAAAAGTCCCCTAGGTAGTAAATCTTCTAGTATGGAATTACACAGAGAGGAAAACAGAGAGTCTGGCATGACTACTGCATTTATTCATG
CTCTAGAGAGGAGATCAAGCCTACCTTTAGATCATGGTTCACCAGCACAGGAAAATCCTGAAAGTGAAAAGAGCTCACCTGCAGTGTCCA
GGTCTAAAACTTTTACTGGGCGTTTCAAGCAGCAAACCCCCTCTCGAACTCATAAAGAACGTTCAACTTCTTTGTCAGCACTGGTGCGTT
CTTCGCCACATGGCTCGTTGGGTTCTGTAGTAAATTCTTTGTCAGGGCTAAAGCTGGATAATATACTCTCAGGGCCCAAGATAGATGTCC
TGAAATCTGGTATGAAACAAGCAGCGACAGTAGCCAGTAAGATGTGGGTAGCTGTTGCGTCTGCCTACAGCTACTCAGATGATGAGGAAG
AAACTAATAGAGACTACAGCTTCCCAGCTGGCCTAGAAGACCATATTTTGGGGGAGAATATATCGCCTAACACAAGTATCTCAGGGTTGG
TCCCCAGTGAACTTACCCAGAGCAACACAAGTCTTGGCAGTAGCAGCAGTAGTGGAGATGTAGGAAAACTGCATTATCCAACAGGTGAAG
TTCCATTTCCAAGAGGCATGAAAGGGCAAGACTTTGAAAAATCAGATCATGGTTCTTCTCAAAATACCAGCATGTCTAGCATCTATCAGA
ATTGTGCAATGGAGGTTTTGATGTCCAGTTGTTCACAGTGTAGAGCTTGTGGAGCTTTAGTTTATGATGAAGAAATTATGGCTGGATGGA
CAGCAGATGACTCAAATTTGAATACAGCTTGTCCATTCTGTAAAAGCAACTTCTTGCCTCTTCTCAATATAGAATTCAAAGATTTGAGAG
GTTCTGCAAGCTTTTTCCTGAAACCAAGTACCTCTGGTGACAGTTTACAAAGTGGAAGCATTCCATTGGCAAATGAATCCTTGGAGCACA
AACCTGTATCCAGTTTAGCAGAACCTGACTTGATCAACTTTATGGACTTCCCAAAACATAACCAGATCATAACTGAAGAAACAGGCTCTG
CAGTTGAACCAAGGTCCCGTTTAATGGATTCTGACATGGATTATGAAAGGCCAAACGTAGAGACCATCAAGTGCGTTGTGGTGGGGGACA
ACGCCGTGGGTAAGACCAGGCTCATCTGTGCCCGCGCTTGCAATGCCACCCTCACCCAGTACCAGCTGCTGGCCACGCATGTGCCCACAG
TATGGGCCATCGACCAATATCGTGTGTGCCAGGAGGTGCTGGAACGCTCCCGAGACGTGGTAGATGATGTCAGCGTCTCTCTGCGCCTCT
GGGACACCTTTGGAGACCACCACAAAGACCGTCGCTTTGCTTATGGGAGATCTGATGTGGTGGTTCTGTGCTTCTCCATTGCCAACCCCA
ATTCCCTCCACCATGTCAAGACCATGTGGTACCCAGAAATCAAGCACTTCTGCCCCCGAGCACCTGTCATCTTGGTGGGCTGCCAGTTGG
ACCTGCGCTACGCTGACCTGGAGGCTGTCAACAGGGCTAGGCGACCCTTGGCTAGGCCCATCAAACCTAATGAAATCCTGCCCCCAGAGA
AGGGTCGGGAGGTGGCCAAGGAGCTGGGCATCCCCTACTATGAGACCAGCGTGGTGGCCCAGTTCGGCATCAAGGACGTCTTTGACAACG
CCATCCGAGCTGCACTCATCTCCCGCCGCCACCTGCAGTTCTGGAAGTCCCACCTCCGCAATGTGCAGCGGCCTCTGCTGCAGGCACCCT
TCCTACCCCCCAAGCCACCGCCCCCGATCATCGTGGTGCCCGACCCTCCCTCCAGCAGCGAGGAGTGCCCCGCCCACCTCCTGGAGGACC
CGCTCTGCGCGGACGTCATCCTGGTGCTGCAGGAGCGGGTGCGCATCTTTGCCCACAAGATCTACCTCTCCACCTCTTCCTCCAAGTTCT
ATGACCTGTTCCTCATGGACCTGAGTGAGGGGGAGCTGGGGGGCCCCTCGGAGCCAGGGGGCACCCACCCAGAGGACCACCAGGGCCACT
CTGATCAACACCACCACCATCACCACCACCACCATGGGCGAGACTTCCTGCTCCGAGCAGCCAGCTTTGACGTGTGCGAGAGCGTGGATG
AGGCTGGGGGCTCCGGTCCTGCTGGCCTCCGTGCTTCCACCAGCGACGGGATCTTACGGGGCAACGGAACAGGGTACCTACCGGGCAGGG
GTCGTGTGCTGTCTTCCTGGAGCCGAGCTTTTGTGAGCATCCAGGAAGAGATGGCAGAAGATCCTCTCACCTACAAATCCCGGCTGATGG
TGGTGGTGAAGATGGACAGTTCCATCCAGCCGGGGCCCTTCCGGGCTGTCCTCAAGTACCTGTACACGGGGGAGCTAGATGAGAACGAGC
GTGACCTCATGCACATTGCCCACATTGCTGAGCTGCTCGAGGTCTTTGATCTGCGCATGATGGTGGCCAACATTCTCAACAATGAGGCCT
TCATGAACCAGGAGATCACCAAGGCCTTCCACGTCCGCCGGACCAACCGGGTTAAGGAGTGCTTGGCAAAAGGCACCTTCTCAGATGTGA
CCTTCATCCTGGATGATGGCACCATCAGCGCCCACAAGCCCCTGTTGATTTCCAGCTGTGACTGGATGGCTGCCATGTTTGGGGGGCCAT
TTGTGGAGAGCTCCACCCGGGAGGTGGTGTTTCCCTACACAAGCAAGAGCTGCATGCGGGCCGTGCTGGAATACCTCTACACCGGCATGT
TCACCTCCAGCCCCGACCTGGATGACATGAAGCTCATCATTCTAGCCAACCGCCTCTGCCTGCCACACCTGGTTGCCCTCACAGAGCAGT
ACACAGTGACCGGGCTGATGGAAGCGACCCAGATGATGGTGGACATCGATGGGGACGTCCTTGTGTTCCTGGAACTGGCTCAGTTCCACT
GTGCGTACCAGCTGGCCGACTGGTGTCTCCACCACATCTGCACCAACTACAACAACGTGTGCCGCAAGTTCCCCCGAGACATGAAGGCCA
TGTCCCCAGAAAACCAGGAGTATTTCGAGAAGCATCGGTGGCCACCTGTGTGGTACCTGAAGGAGGAAGATCATTACCAGCGGGCACGGA
AGGAGCGTGAGAAGGAGGACTACCTCCACCTCAAGCGGCAGCCCAAACGGCGTTGGCTCTTCTGGAACAGTCCATCCTCCCCGTCTTCCT
CGGCAGCCTCCTCCTCATCCCCATCTTCCTCCTCGGCTGTGGTCTGAGATGCTGCCACCCTCTTCTGACCCTGCTGCTGTTGTCCCCATC
CGCCTTCACCCCTCTGCTCTTCCGCATCACCCCATCCACCTTACAGGGACCAGGGGGCCCACGTAACCAGGACCCAGAGGGTGGAGCTCT
TCTTACCAGCCACCGTGGCTCAGCCAGAGAGGAGCTGAGCCCTGTGGAGCAGAACGGGAACCACCTGCAGAGGTCCCCAGACCCAAAGCA
GGACGGGAGACAACTGCTTGGAGGAGCGAAGAGCCCTGGCATTTTATCTCTGGGTTTGAGAGCCCTAGAGTCAAAGGGAAAGCCTCCCAG
CCTCCAGGGCTTCTCTGTGTGTCTTGGTTGCTGCTCTGGCCAGGGAGGCAGCCCCACTCCCAGCAAGCAGAAGTGATCCTCGAGGGTCCT
GCCCCTGTTGGCCATATCTTTCCACCGACGGACTTGAGTGTTGCATTTGTTTTGTGGGCATTTCCACACGAAGCCTACTCACACCCTCAC
TGGAGAAGTCAGGGTAGAAATTGAGCCTTCAGAGCCCAACTCAAGGCTTCTACATCCTGGGGTGCAGCTGCAAAAGGCCAGACGTGGAAA
GGCCTGTATCCTGCCAGTGTCCCTCCGTCCCAGGGGGCTGTGCTAGCACAGACCTGAGAATGGGGACACAGGTCATTCAGAGCTCCAGGC
CTGGAAGCAGTGCCTCTTGGTGCAACAAGAAACTTCTCCCTCACCCCCTCCTTTACCCTCAGATTTGGAGATGGTAACCAAAGGAAGCAG
CTGGGACAGGTGGAGAAGGAAGTAGGAATGAGTGCACGGCGACCCCGTGCTCCTCAGGGCCCTCCCCTGCCTCTGGGTGGCACTGCTTTT
TATAGGGTGGGGCAAAATTAGCAAAAAACAAAAACCAATGACAACCAAACTGAAACCGAAACGAAAAATCAACAAACACTCTGTCCTCTA

>22263_22263_11_DENND4C-RHOBTB2_DENND4C_chr9_19357152_ENST00000602925_RHOBTB2_chr8_22861938_ENST00000519685_length(amino acids)=2386AA_BP=1648
MRRRRPLELVPRPALPSAPSPRIRCFLAPGRSRVGAALTEEQAAENTVAAMIEDKGPRVTDYFVVAGLTDTSTLLDQEINRLDTKSTGPK
APITDIAIIIKSAGETVPEGYTCVEATPSALQANLNYGSLKSPELFLCYKRGRDKPPLTDIGVLYEGKERLIPGCEVILATPYGRCANVN
NSSTTSQRIFITYRRAPPVRPQNSLAVTDICVIVTSKGETPPHTFCKVDKNLNCGMWGSSVFLCYKKSVPASNAIAYKAGLIFRYPEEDY
ESFPLSESDVPLFCLPMGATIECWDPETKYPLPVFSTFVLTGSSAKKVYGAAIQFYEPYSRELLSEKQLMHLGLLTPVERKMVSKSINTN
KCICLLSHWPFFEAFRKFLMFIYKLSVSGPHPLPIEKHISHFMQNIPFPSPQRPRILVQLSVHDALILSQPVSTPLPLSGANFSTLLMNL
GPENCATLLLFVLLESKILLHSLRPAVLTGVAEAVVAMIFPFQWQCPYIPLCPLSLAAVLSAPLPFIVGVDSRYFDLHDPPQDVVCIDLD
TNMLYVSDEKKNMNWKQLPKKPCKNLLSTLKKLYPQLSSVHQKTQEGSAIDMTPIEADFSWQKKMTQLEMEIQEAFLRFMASILKGYRTY
LRPITEAPSNKATAADSLFDRQGFLKSRDRAYAKFYTLLSKTQIFIRFIEECSFVSDKDTGLAFFDDCIEKLFPDKGTEKTDKVDFDSAE
DTRLIELDDSQKSEHTVFIMPPEPPPDDGKDLSPKYSYKYFPRLDLKLFDRPQELKLCFSRHPTGNSITKSPPLMAKRTKQEIKTAHKLA
KRCYTNPPQWAKCLFSHCYSLWFICLPAYVRVSHPKVRALQQAYDVLIKMRKTDVDPLDEVCYRVVMQLCGLWGHPVLAVRVLFEMKTAR
IKPNAITYGYYNKVVLESPWPSSTRSGIFLWTKVRNVVRGLAQFRQPLKKTVQRSQVSSISGGQSDQGYGSKDELIKDDAEIHVPEEQAA
RELITKTKMQTEEVCDASAIVAKHSQPSPEPHSPTEPPAWGSSIVKVPSGIFDVNSRKSSTGSISNVLFSTQDPVEDAVFGEATNLKKNG
DRGEKRQKHFPERSCSFSSESRAGMLLKKSSLDSNSSEMAIMMGADAKILTAALTCPKTSLLHIARTHSFENVSCHLPDSRTCMSESTWN
PEHRSSPVPEMLEESQELLEPVVDDVPKTTATVDTYESLLSDSNSNQSRDLKTVSKDLRNKRSSLYGIAKVVQREDVETGLDPLSLLATE
CTGGKTPDSEDKLFSPVIARNLADEIESYMNLKSPLGSKSSSMELHREENRESGMTTAFIHALERRSSLPLDHGSPAQENPESEKSSPAV
SRSKTFTGRFKQQTPSRTHKERSTSLSALVRSSPHGSLGSVVNSLSGLKLDNILSGPKIDVLKSGMKQAATVASKMWVAVASAYSYSDDE
EETNRDYSFPAGLEDHILGENISPNTSISGLVPSELTQSNTSLGSSSSSGDVGKLHYPTGEVPFPRGMKGQDFEKSDHGSSQNTSMSSIY
QNCAMEVLMSSCSQCRACGALVYDEEIMAGWTADDSNLNTACPFCKSNFLPLLNIEFKDLRGSASFFLKPSTSGDSLQSGSIPLANESLE
HKPVSSLAEPDLINFMDFPKHNQIITEETGSAVEPRSRLMDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVP
TVWAIDQYRVCQEVLERSRDVVDDVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPRAPVILVGCQ
LDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKELGIPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQA
PFLPPKPPPPIIVVPDPPSSSEECPAHLLEDPLCADVILVLQERVRIFAHKIYLSTSSSKFYDLFLMDLSEGELGGPSEPGGTHPEDHQG
HSDQHHHHHHHHHGRDFLLRAASFDVCESVDEAGGSGPAGLRASTSDGILRGNGTGYLPGRGRVLSSWSRAFVSIQEEMAEDPLTYKSRL
MVVVKMDSSIQPGPFRAVLKYLYTGELDENERDLMHIAHIAELLEVFDLRMMVANILNNEAFMNQEITKAFHVRRTNRVKECLAKGTFSD
VTFILDDGTISAHKPLLISSCDWMAAMFGGPFVESSTREVVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIILANRLCLPHLVALTE
QYTVTGLMEATQMMVDIDGDVLVFLELAQFHCAYQLADWCLHHICTNYNNVCRKFPRDMKAMSPENQEYFEKHRWPPVWYLKEEDHYQRA

--------------------------------------------------------------
>22263_22263_12_DENND4C-RHOBTB2_DENND4C_chr9_19357152_ENST00000602925_RHOBTB2_chr8_22861938_ENST00000522948_length(transcript)=10150nt_BP=5233nt
GGAGGAAAGGGAGAGGGAGGGGGAAAAGAAAGTGCTGTTTTGTGGAAAGGGGCGGAAGGCGGGGGAGAAAAAGGGAACAGAAACATGGCG
GTCAGGTCTTGGGACGGCTGCGCCGCGGGCAGCTCCTAGGCGACGCGCCGCCCGCACTGTCCGACGGCTCACAGCGCGGAGGCACCCGCG
CGGGCCAGCGCTCCGGCCATCGCCCCTGGCTGTAGGCGGCGCCCCTCGGAGACCCTGCCCGCGAGGCGGCGCAGGCGCAGACCGGACTGA
GGCGGCGGCGGCCGCTGGAGCTAGTCCCCCGCCCTGCCCTGCCGAGCGCGCCCAGTCCGCGAATCCGGTGCTTTCTTGCCCCAGGAAGAA
GCCGTGTCGGGGCTGCGCTGACAGAGGAGCAGGCAGCAGAAAATACAGTAGCAGCCATGATAGAAGACAAAGGACCAAGAGTGACAGACT
ACTTTGTCGTAGCTGGTCTCACTGACACATCTACTCTTTTGGATCAAGAAATAAATCGTTTAGATACTAAGTCAACTGGACCTAAAGCTC
CAATTACAGACATTGCCATTATTATCAAATCAGCTGGAGAAACAGTACCTGAAGGTTACACCTGTGTAGAAGCCACTCCATCAGCTCTCC
AAGCAAACTTGAACTATGGAAGTCTGAAAAGCCCAGAACTTTTCCTCTGTTATAAGAGAGGGAGAGATAAACCACCGCTTACAGATATTG
GAGTTCTATATGAAGGGAAAGAACGGCTTATTCCAGGATGTGAAGTGATCCTAGCCACACCCTATGGTCGCTGTGCCAATGTCAACAATA
GTTCAACTACTTCACAAAGAATCTTTATCACTTATCGAAGGGCTCCTCCAGTTCGACCCCAGAATTCCTTGGCTGTAACTGATATCTGTG
TTATTGTAACCAGTAAAGGAGAAACTCCTCCTCATACCTTCTGCAAAGTTGACAAAAACTTAAATTGTGGAATGTGGGGTTCCAGCGTGT
TTCTGTGTTATAAGAAGTCTGTACCTGCTTCAAATGCAATAGCATATAAGGCTGGTTTAATTTTTAGATATCCAGAAGAGGACTATGAGT
CATTTCCACTCTCAGAATCAGATGTACCTCTTTTCTGCCTTCCTATGGGAGCTACTATTGAGTGCTGGGATCCTGAAACCAAATATCCAC
TTCCAGTTTTTTCAACTTTTGTCTTGACAGGTTCTTCAGCCAAAAAGGTATATGGAGCTGCCATTCAGTTTTATGAACCTTACTCTCGGG
AACTTCTATCAGAGAAACAGCTTATGCACCTGGGCTTGTTGACGCCTGTGGAGAGAAAAATGGTCTCCAAATCCATCAATACAAACAAAT
GCATTTGTTTACTCTCACACTGGCCTTTTTTTGAAGCTTTTAGGAAATTTCTTATGTTTATCTACAAACTTTCTGTGTCTGGACCACATC
CTCTTCCCATTGAAAAGCACATTTCACATTTTATGCAAAACATCCCTTTTCCTTCACCACAAAGACCGAGAATCCTTGTCCAGCTGTCAG
TCCATGATGCATTAATATTATCACAGCCAGTTTCTACACCTTTACCACTAAGTGGAGCCAACTTTAGCACCTTGCTAATGAATCTGGGTC
CTGAGAATTGTGCAACACTGCTGCTCTTTGTTTTACTTGAGAGTAAAATTCTGCTGCATTCTCTTAGGCCAGCTGTCTTGACTGGGGTAG
CTGAAGCTGTTGTAGCTATGATCTTTCCATTTCAGTGGCAATGCCCATATATTCCCCTTTGTCCTCTTTCACTGGCTGCAGTGCTTAGTG
CACCTTTACCATTTATAGTTGGAGTTGACTCAAGGTATTTTGATCTTCATGACCCACCACAAGATGTTGTTTGCATTGACTTGGATACGA
ACATGTTATATGTATCAGATGAAAAGAAGAACATGAACTGGAAGCAACTTCCCAAAAAGCCGTGCAAAAATCTACTTAGCACCTTAAAGA
AATTGTATCCCCAGCTGTCTTCAGTTCACCAAAAAACTCAAGAAGGCTCAGCGATTGACATGACTCCAATTGAAGCAGATTTCTCCTGGC
AAAAGAAGATGACACAGCTTGAGATGGAAATTCAAGAGGCATTTTTGCGCTTTATGGCGTCTATTTTAAAAGGATATAGAACATATCTCA
GACCAATCACAGAGGCTCCTTCAAATAAAGCCACAGCTGCTGATTCATTGTTTGACCGACAGGGATTTTTAAAAAGTCGAGATCGTGCCT
ATGCAAAATTCTATACCCTTTTATCCAAAACACAGATTTTTATTCGTTTCATTGAAGAATGCAGTTTTGTAAGTGATAAAGATACTGGAT
TAGCATTTTTTGATGACTGCATAGAAAAGTTGTTTCCTGATAAAGGCACAGAGAAAACAGATAAGGTTGATTTTGATTCAGCAGAAGATA
CCAGATTGATAGAACTAGATGATTCACAGAAAAGTGAGCATACTGTATTTATAATGCCGCCAGAGCCACCTCCTGATGATGGAAAGGACC
TGTCACCAAAGTACAGTTACAAATACTTTCCAAGACTGGACCTTAAGCTTTTTGACAGACCGCAGGAGTTGAAACTTTGTTTTAGTAGAC
ACCCTACTGGGAATAGCATTACAAAGAGTCCACCTCTCATGGCTAAGAGAACTAAACAGGAAATAAAAACAGCTCATAAATTGGCGAAGA
GATGTTATACAAATCCACCACAGTGGGCCAAGTGTCTGTTTAGTCATTGTTACAGTTTATGGTTTATTTGTCTTCCGGCCTATGTTAGAG
TTTCTCATCCTAAAGTCAGAGCACTTCAGCAGGCATATGATGTACTTATTAAGATGAGGAAAACAGATGTGGATCCCTTAGATGAGGTGT
GCTATCGAGTAGTGATGCAGCTTTGTGGACTTTGGGGTCATCCTGTTTTAGCAGTGAGAGTCTTATTTGAAATGAAAACTGCTAGGATAA
AGCCTAATGCTATTACTTATGGTTATTATAATAAGGTAGTCTTGGAGAGCCCGTGGCCTAGCAGTACCCGCAGTGGTATTTTCTTATGGA
CGAAGGTACGGAATGTGGTACGTGGCTTGGCACAGTTTAGGCAGCCGCTTAAAAAGACTGTGCAAAGGTCACAGGTCTCCTCAATATCAG
GTGGTCAGTCTGACCAAGGATACGGGTCTAAGGATGAACTTATAAAGGATGATGCAGAAATTCATGTGCCTGAAGAACAGGCAGCAAGAG
AATTGATAACTAAAACAAAAATGCAAACAGAAGAGGTGTGTGATGCCTCTGCTATTGTGGCAAAACATTCACAACCTAGTCCAGAGCCTC
ACAGTCCTACTGAACCTCCTGCATGGGGCAGCAGTATTGTGAAAGTTCCGTCTGGTATATTTGATGTCAACAGCAGGAAAAGTAGCACTG
GTAGTATATCAAATGTGCTGTTTTCTACTCAAGATCCAGTTGAAGATGCAGTCTTTGGCGAAGCTACTAATCTCAAGAAGAATGGTGATA
GAGGAGAAAAAAGACAAAAGCATTTTCCTGAGAGGAGTTGTAGTTTTAGTTCTGAAAGTCGAGCAGGAATGTTGCTTAAGAAGAGTAGTT
TGGATTCGAATTCAAGTGAAATGGCTATCATGATGGGAGCAGATGCCAAGATTCTCACAGCAGCATTGACATGTCCTAAGACTTCTCTAC
TTCATATTGCAAGAACCCATAGCTTTGAGAATGTTAGCTGTCACCTACCTGATAGTAGGACTTGTATGTCTGAAAGCACTTGGAATCCTG
AGCACAGATCATCTCCGGTGCCAGAGATGCTTGAGGAAAGCCAAGAACTCCTTGAGCCTGTGGTTGATGACGTACCTAAAACTACTGCAA
CAGTAGATACATATGAGAGTCTACTAAGTGATAGTAACAGTAATCAGTCCAGAGACTTGAAAACAGTATCCAAAGATCTGAGGAATAAGA
GAAGTAGTTTATATGGTATTGCTAAGGTGGTTCAGAGGGAAGATGTTGAAACTGGACTAGATCCTTTGTCTCTTTTAGCCACTGAATGTA
CAGGAGGAAAAACTCCTGATTCTGAAGATAAGTTGTTTTCTCCAGTTATTGCACGTAATCTGGCTGATGAAATAGAAAGCTATATGAACC
TAAAAAGTCCCCTAGGTAGTAAATCTTCTAGTATGGAATTACACAGAGAGGAAAACAGAGAGTCTGGCATGACTACTGCATTTATTCATG
CTCTAGAGAGGAGATCAAGCCTACCTTTAGATCATGGTTCACCAGCACAGGAAAATCCTGAAAGTGAAAAGAGCTCACCTGCAGTGTCCA
GGTCTAAAACTTTTACTGGGCGTTTCAAGCAGCAAACCCCCTCTCGAACTCATAAAGAACGTTCAACTTCTTTGTCAGCACTGGTGCGTT
CTTCGCCACATGGCTCGTTGGGTTCTGTAGTAAATTCTTTGTCAGGGCTAAAGCTGGATAATATACTCTCAGGGCCCAAGATAGATGTCC
TGAAATCTGGTATGAAACAAGCAGCGACAGTAGCCAGTAAGATGTGGGTAGCTGTTGCGTCTGCCTACAGCTACTCAGATGATGAGGAAG
AAACTAATAGAGACTACAGCTTCCCAGCTGGCCTAGAAGACCATATTTTGGGGGAGAATATATCGCCTAACACAAGTATCTCAGGGTTGG
TCCCCAGTGAACTTACCCAGAGCAACACAAGTCTTGGCAGTAGCAGCAGTAGTGGAGATGTAGGAAAACTGCATTATCCAACAGGTGAAG
TTCCATTTCCAAGAGGCATGAAAGGGCAAGACTTTGAAAAATCAGATCATGGTTCTTCTCAAAATACCAGCATGTCTAGCATCTATCAGA
ATTGTGCAATGGAGGTTTTGATGTCCAGTTGTTCACAGTGTAGAGCTTGTGGAGCTTTAGTTTATGATGAAGAAATTATGGCTGGATGGA
CAGCAGATGACTCAAATTTGAATACAGCTTGTCCATTCTGTAAAAGCAACTTCTTGCCTCTTCTCAATATAGAATTCAAAGATTTGAGAG
GTTCTGCAAGCTTTTTCCTGAAACCAAGTACCTCTGGTGACAGTTTACAAAGTGGAAGCATTCCATTGGCAAATGAATCCTTGGAGCACA
AACCTGTATCCAGTTTAGCAGAACCTGACTTGATCAACTTTATGGACTTCCCAAAACATAACCAGATCATAACTGAAGAAACAGGCTCTG
CAGTTGAACCAAGGTCCCGTTTAATGGATTCTGACATGGATTATGAAAGGCCAAACGTAGAGACCATCAAGTGCGTTGTGGTGGGGGACA
ACGCCGTGGGTAAGACCAGGCTCATCTGTGCCCGCGCTTGCAATGCCACCCTCACCCAGTACCAGCTGCTGGCCACGCATGTGCCCACAG
TATGGGCCATCGACCAATATCGTGTGTGCCAGGAGGTGCTGGAACGCTCCCGAGACGTGGTAGATGATGTCAGCGTCTCTCTGCGCCTCT
GGGACACCTTTGGAGACCACCACAAAGACCGTCGCTTTGCTTATGGGAGATCTGATGTGGTGGTTCTGTGCTTCTCCATTGCCAACCCCA
ATTCCCTCCACCATGTCAAGACCATGTGGTACCCAGAAATCAAGCACTTCTGCCCCCGAGCACCTGTCATCTTGGTGGGCTGCCAGTTGG
ACCTGCGCTACGCTGACCTGGAGGCTGTCAACAGGGCTAGGCGACCCTTGGCTAGGCCCATCAAACCTAATGAAATCCTGCCCCCAGAGA
AGGGTCGGGAGGTGGCCAAGGAGCTGGGCATCCCCTACTATGAGACCAGCGTGGTGGCCCAGTTCGGCATCAAGGACGTCTTTGACAACG
CCATCCGAGCTGCACTCATCTCCCGCCGCCACCTGCAGTTCTGGAAGTCCCACCTCCGCAATGTGCAGCGGCCTCTGCTGCAGGCACCCT
TCCTACCCCCCAAGCCACCGCCCCCGATCATCGTGGTGCCCGACCCTCCCTCCAGCAGCGAGGAGTGCCCCGCCCACCTCCTGGAGGACC
CGCTCTGCGCGGACGTCATCCTGGTGCTGCAGGAGCGGGTGCGCATCTTTGCCCACAAGATCTACCTCTCCACCTCTTCCTCCAAGTTCT
ATGACCTGTTCCTCATGGACCTGAGTGAGGGGGAGCTGGGGGGCCCCTCGGAGCCAGGGGGCACCCACCCAGAGGACCACCAGGGCCACT
CTGATCAACACCACCACCATCACCACCACCACCATGGGCGAGACTTCCTGCTCCGAGCAGCCAGCTTTGACGTGTGCGAGAGCGTGGATG
AGGCTGGGGGCTCCGGTCCTGCTGGCCTCCGTGCTTCCACCAGCGACGGGATCTTACGGGGCAACGGAACAGGGTACCTACCGGGCAGGG
GTCGTGTGCTGTCTTCCTGGAGCCGAGCTTTTGTGAGCATCCAGGAAGAGATGGCAGAAGATCCTCTCACCTACAAATCCCGGCTGATGG
TGGTGGTGAAGATGGACAGTTCCATCCAGCCGGGGCCCTTCCGGGCTGTCCTCAAGTACCTGTACACGGGGGAGCTAGATGAGAACGAGC
GTGACCTCATGCACATTGCCCACATTGCTGAGCTGCTCGAGGTCTTTGATCTGCGCATGATGGTGGCCAACATTCTCAACAATGAGGCCT
TCATGAACCAGGAGATCACCAAGGCCTTCCACGTCCGCCGGACCAACCGGGTTAAGGAGTGCTTGGCAAAAGGCACCTTCTCAGATGTGA
CCTTCATCCTGGATGATGGCACCATCAGCGCCCACAAGCCCCTGTTGATTTCCAGCTGTGACTGGATGGCTGCCATGTTTGGGGGGCCAT
TTGTGGAGAGCTCCACCCGGGAGGTGGTGTTTCCCTACACAAGCAAGAGCTGCATGCGGGCCGTGCTGGAATACCTCTACACCGGCATGT
TCACCTCCAGCCCCGACCTGGATGACATGAAGCTCATCATTCTAGCCAACCGCCTCTGCCTGCCACACCTGGTTGCCCTCACAGAGCAGT
ACACAGTGACCGGGCTGATGGAAGCGACCCAGATGATGGTGGACATCGATGGGGACGTCCTTGTGTTCCTGGAACTGGCTCAGTTCCACT
GTGCGTACCAGCTGGCCGACTGGTGTCTCCACCACATCTGCACCAACTACAACAACGTGTGCCGCAAGTTCCCCCGAGACATGAAGGCCA
TGTCCCCAGAAAACCAGGAGTATTTCGAGAAGCATCGGTGGCCACCTGTGTGGTACCTGAAGGAGGAAGATCATTACCAGCGGGCACGGA
AGGAGCGTGAGAAGGAGGACTACCTCCACCTCAAGCGGCAGCCCAAACGGCGTTGGCTCTTCTGGAACAGTCCATCCTCCCCGTCTTCCT
CGGCAGCCTCCTCCTCATCCCCATCTTCCTCCTCGGCTGTGGTCTGAGATGCTGCCACCCTCTTCTGACCCTGCTGCTGTTGTCCCCATC
CGCCTTCACCCCTCTGCTCTTCCGCATCACCCCATCCACCTTACAGGGACCAGGGGGCCCACGTAACCAGGACCCAGAGGGTGGAGCTCT
TCTTACCAGCCACCGTGGCTCAGCCAGAGAGGAGCTGAGCCCTGTGGAGCAGAACGGGAACCACCTGCAGAGGTCCCCAGACCCAAAGCA
GGACGGGAGACAACTGCTTGGAGGAGCGAAGAGCCCTGGCATTTTATCTCTGGGTTTGAGAGCCCTAGAGTCAAAGGGAAAGCCTCCCAG
CCTCCAGGGCTTCTCTGTGTGTCTTGGTTGCTGCTCTGGCCAGGGAGGCAGCCCCACTCCCAGCAAGCAGAAGTGATCCTCGAGGGTCCT
GCCCCTGTTGGCCATATCTTTCCACCGACGGACTTGAGTGTTGCATTTGTTTTGTGGGCATTTCCACACGAAGCCTACTCACACCCTCAC
TGGAGAAGTCAGGGTAGAAATTGAGCCTTCAGAGCCCAACTCAAGGCTTCTACATCCTGGGGTGCAGCTGCAAAAGGCCAGACGTGGAAA
GGCCTGTATCCTGCCAGTGTCCCTCCGTCCCAGGGGGCTGTGCTAGCACAGACCTGAGAATGGGGACACAGGTCATTCAGAGCTCCAGGC
CTGGAAGCAGTGCCTCTTGGTGCAACAAGAAACTTCTCCCTCACCCCCTCCTTTACCCTCAGATTTGGAGATGGTAACCAAAGGAAGCAG
CTGGGACAGGTGGAGAAGGAAGTAGGAATGAGTGCACGGCGACCCCGTGCTCCTCAGGGCCCTCCCCTGCCTCTGGGTGGCACTGCTTTT
TATAGGGTGGGGCAAAATTAGCAAAAAACAAAAACCAATGACAACCAAACTGAAACCGAAACGAAAAATCAACAAACACTCTGTCCTCTA
TCCCTCCAAAGAATGAAAATCAGAAAAAGCCCCTGCCTAGCTCACATTTCTATAAACAGAGGCCCCCATGATGAGGAGGTGAAGATTTAG
GTTGCAGAATCGACTCCAATGCCTTTCAGGAAAGGACTCGGCACTTCTCTGACTGCGGAGGCCCTGACCCTGCCAGCTGGCTCCGAGGGC
AACACAGGGGCCTGGCCTCTAGAGGGCTGGTGATTGAGGGGCCCGGGCTGGCGGCAAAGAGGGGTTTGGTCTCGGGGCTTAAATGGCACC
AGACTCTTGCTTTTGCCCATCTGGAGACTGCAGGCTCCCTTCCTTACCCTCAGAGAGTGCTTATGGTGGGTGTTTTTGCGGGGCTGCAAT
AGGGGCCAAAAGTCAGGGAAAGGGGCACTGACCTGTAGTGAAAGGCCACAGGACACAGCCTTATTACTGCTGGGGTGGGATAAGGGGAAG
GAGAAGAGGGAGAATGGAGCAGGAGGAAAAGCAGAGTTGGTCTAGAGAGGAGGAGGGCGGGGCTGGAGGAATGTGGGGGATTGAAACTAG
CTCCCAGCCCCCATGGGGCAGCAGCTGGGCCACAATTGCCCCTTTCCGTTTTCTAACCCCGACTCAGATTTCACCACCCACACTCTTTTT
AGGTGTAAAAGATGGAGTCCCACGGAGGAGGGGCAGAGCCAGGAGGCAGTGGGGCTGTGGGCTCAGAGCTCAGGAGTCGCCTTACCTGAG
AGAGATGTTCTAGCTGAGAGGGCCTGGCCCTGGGGTGGGCTCCAGGAAAACGCTGGTTAGGCCTGGGATTGAGCTAACCTGAAACAAAGG
TAGCAGGCAGGACCTAATGACCAGAGGTTAAATCCTCATCAAGAGAGACCAGGCGGCTGGAGGACAAGCGGCTCTAACCCTGGGGGCGGC
CATGTTGTCCAGGCCCAGGCCCCTCCAGGACTGTGGCTGCCTCCCCTCCACGGCCTCCAGGGCGGCTGGCTGGAAAGCCACGCGTATGCT
GCCCTCTACAGGCTGCTCGGCCTCCCTGCAGCTCAGCGCAGCCCAGGGCTCCAAGTGAGGCCCAGAAGCCCATGGGCAGGGCTGGGGGGA
CGAAGGGGGAACCCGGAGCACCTCCACTTCTAGGGAAGATGGACAGCGTGGGGGCACACCTGGGCCTCCCGGAAGCTGTGGACGAAAGGG
AGAGCGGGTCCTCCAGGGCAAGGGGAACGGGAAATAGGTCTCCTAGGTGCCTGAAGCGCTGAGCAACCTGGGTACCCTGGTGGGGATGCA
GGGAAGGCCGGGGCAGAGAAAGTGAAGGTCGACCCAGGGCTGTAGGAAGCCATAGGAGAGTGACCACGGGATTCCCTGAGAAACAGGGCC
GGCCCCCCAACTTCAGGGACCCACCGCCCATTCCCCGAGAGCTGTCGGAACCAGATGCAACCCGGCAGCCCAGAGAACTCTCCTGGGAGG
CTGTGGGTGAGCCAGGCCAACATTGGTGTCCCTGTCCCCAGAGGGAGGAGCAGGCAGGAGAGAGAGGGGAAGGAGGTATGAATCCCAGTC
CCCAGGAACCTAGCTCTTTAAACTCTGGGGAGTCGGATTCAGGAAACACCCCCAGGAGGCCAAGCCTGAAAACAGAGGGGAGGGAGGAAG
GAAGGAGTCCCAGCAGGAGCACAGCCCTGGTTTCCTGTCACTCAGAGCTGATTCACAGGAGGAGGGGAGGTTGGGGGGCGGGAGACAAAA

>22263_22263_12_DENND4C-RHOBTB2_DENND4C_chr9_19357152_ENST00000602925_RHOBTB2_chr8_22861938_ENST00000522948_length(amino acids)=2386AA_BP=1648
MRRRRPLELVPRPALPSAPSPRIRCFLAPGRSRVGAALTEEQAAENTVAAMIEDKGPRVTDYFVVAGLTDTSTLLDQEINRLDTKSTGPK
APITDIAIIIKSAGETVPEGYTCVEATPSALQANLNYGSLKSPELFLCYKRGRDKPPLTDIGVLYEGKERLIPGCEVILATPYGRCANVN
NSSTTSQRIFITYRRAPPVRPQNSLAVTDICVIVTSKGETPPHTFCKVDKNLNCGMWGSSVFLCYKKSVPASNAIAYKAGLIFRYPEEDY
ESFPLSESDVPLFCLPMGATIECWDPETKYPLPVFSTFVLTGSSAKKVYGAAIQFYEPYSRELLSEKQLMHLGLLTPVERKMVSKSINTN
KCICLLSHWPFFEAFRKFLMFIYKLSVSGPHPLPIEKHISHFMQNIPFPSPQRPRILVQLSVHDALILSQPVSTPLPLSGANFSTLLMNL
GPENCATLLLFVLLESKILLHSLRPAVLTGVAEAVVAMIFPFQWQCPYIPLCPLSLAAVLSAPLPFIVGVDSRYFDLHDPPQDVVCIDLD
TNMLYVSDEKKNMNWKQLPKKPCKNLLSTLKKLYPQLSSVHQKTQEGSAIDMTPIEADFSWQKKMTQLEMEIQEAFLRFMASILKGYRTY
LRPITEAPSNKATAADSLFDRQGFLKSRDRAYAKFYTLLSKTQIFIRFIEECSFVSDKDTGLAFFDDCIEKLFPDKGTEKTDKVDFDSAE
DTRLIELDDSQKSEHTVFIMPPEPPPDDGKDLSPKYSYKYFPRLDLKLFDRPQELKLCFSRHPTGNSITKSPPLMAKRTKQEIKTAHKLA
KRCYTNPPQWAKCLFSHCYSLWFICLPAYVRVSHPKVRALQQAYDVLIKMRKTDVDPLDEVCYRVVMQLCGLWGHPVLAVRVLFEMKTAR
IKPNAITYGYYNKVVLESPWPSSTRSGIFLWTKVRNVVRGLAQFRQPLKKTVQRSQVSSISGGQSDQGYGSKDELIKDDAEIHVPEEQAA
RELITKTKMQTEEVCDASAIVAKHSQPSPEPHSPTEPPAWGSSIVKVPSGIFDVNSRKSSTGSISNVLFSTQDPVEDAVFGEATNLKKNG
DRGEKRQKHFPERSCSFSSESRAGMLLKKSSLDSNSSEMAIMMGADAKILTAALTCPKTSLLHIARTHSFENVSCHLPDSRTCMSESTWN
PEHRSSPVPEMLEESQELLEPVVDDVPKTTATVDTYESLLSDSNSNQSRDLKTVSKDLRNKRSSLYGIAKVVQREDVETGLDPLSLLATE
CTGGKTPDSEDKLFSPVIARNLADEIESYMNLKSPLGSKSSSMELHREENRESGMTTAFIHALERRSSLPLDHGSPAQENPESEKSSPAV
SRSKTFTGRFKQQTPSRTHKERSTSLSALVRSSPHGSLGSVVNSLSGLKLDNILSGPKIDVLKSGMKQAATVASKMWVAVASAYSYSDDE
EETNRDYSFPAGLEDHILGENISPNTSISGLVPSELTQSNTSLGSSSSSGDVGKLHYPTGEVPFPRGMKGQDFEKSDHGSSQNTSMSSIY
QNCAMEVLMSSCSQCRACGALVYDEEIMAGWTADDSNLNTACPFCKSNFLPLLNIEFKDLRGSASFFLKPSTSGDSLQSGSIPLANESLE
HKPVSSLAEPDLINFMDFPKHNQIITEETGSAVEPRSRLMDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVP
TVWAIDQYRVCQEVLERSRDVVDDVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPRAPVILVGCQ
LDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKELGIPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQA
PFLPPKPPPPIIVVPDPPSSSEECPAHLLEDPLCADVILVLQERVRIFAHKIYLSTSSSKFYDLFLMDLSEGELGGPSEPGGTHPEDHQG
HSDQHHHHHHHHHGRDFLLRAASFDVCESVDEAGGSGPAGLRASTSDGILRGNGTGYLPGRGRVLSSWSRAFVSIQEEMAEDPLTYKSRL
MVVVKMDSSIQPGPFRAVLKYLYTGELDENERDLMHIAHIAELLEVFDLRMMVANILNNEAFMNQEITKAFHVRRTNRVKECLAKGTFSD
VTFILDDGTISAHKPLLISSCDWMAAMFGGPFVESSTREVVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIILANRLCLPHLVALTE
QYTVTGLMEATQMMVDIDGDVLVFLELAQFHCAYQLADWCLHHICTNYNNVCRKFPRDMKAMSPENQEYFEKHRWPPVWYLKEEDHYQRA

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Fusion Gene PPI Analysis for DENND4C-RHOBTB2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for DENND4C-RHOBTB2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for DENND4C-RHOBTB2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneC4693899EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 643GENOMICS_ENGLAND;UNIPROT
TgeneC0036572Seizures1GENOMICS_ENGLAND
TgeneC0557874Global developmental delay1GENOMICS_ENGLAND
TgeneC1847514Postnatal microcephaly1GENOMICS_ENGLAND
TgeneC3714756Intellectual Disability1GENOMICS_ENGLAND
TgeneC4721453Peripheral Nervous System Diseases1CTD_human