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Fusion Gene Summary | |
Fusion Gene ORF analysis | |
Fusion Genomic Features | |
Fusion Protein Features | |
Fusion Gene Sequence | |
Fusion Gene PPI analysis | |
Related Drugs | |
Related Diseases |
Fusion gene:ATF7IP-PDGFRB (FusionGDB2 ID:HG55729TG5159) |
Fusion Gene Summary for ATF7IP-PDGFRB |
Fusion gene summary |
Fusion gene information | Fusion gene name: ATF7IP-PDGFRB | Fusion gene ID: hg55729tg5159 | Hgene | Tgene | Gene symbol | ATF7IP | PDGFRB | Gene ID | 55729 | 5159 |
Gene name | activating transcription factor 7 interacting protein | platelet derived growth factor receptor beta | |
Synonyms | AM|ATF-IP|MCAF|MCAF1|p621 | CD140B|IBGC4|IMF1|JTK12|KOGS|PDGFR|PDGFR-1|PDGFR1|PENTT | |
Cytomap | ('ATF7IP')('PDGFRB') 12p13.1 | 5q32 | |
Type of gene | protein-coding | protein-coding | |
Description | activating transcription factor 7-interacting protein 1ATF-interacting proteinATF7-interacting proteinATFa-associated modulatorMBD1-containing chromatin-associated factor 1 | platelet-derived growth factor receptor betaActivated tyrosine kinase PDGFRBCD140 antigen-like family member BNDEL1-PDGFRBPDGF-R-betaPDGFR-betabeta-type platelet-derived growth factor receptorplatelet-derived growth factor receptor 1platelet-deriv | |
Modification date | 20200313 | 20200329 | |
UniProtAcc | . | P09619 | |
Ensembl transtripts involved in fusion gene | ENST00000261168, ENST00000536444, ENST00000540793, ENST00000543189, ENST00000544627, ENST00000541654, | ||
Fusion gene scores | * DoF score | 16 X 15 X 8=1920 | 28 X 26 X 6=4368 |
# samples | 20 | 15 | |
** MAII score | log2(20/1920*10)=-3.26303440583379 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(15/4368*10)=-4.86393845042397 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
Context | PubMed: ATF7IP [Title/Abstract] AND PDGFRB [Title/Abstract] AND fusion [Title/Abstract] | ||
Most frequent breakpoint | ATF7IP(14634119)-PDGFRB(149506177), # samples:2 | ||
Anticipated loss of major functional domain due to fusion event. | ATF7IP-PDGFRB seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. ATF7IP-PDGFRB seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. ATF7IP-PDGFRB seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. ATF7IP-PDGFRB seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. ATF7IP-PDGFRB seems lost the major protein functional domain in Hgene partner, which is a epigenetic factor due to the frame-shifted ORF. ATF7IP-PDGFRB seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF. ATF7IP-PDGFRB seems lost the major protein functional domain in Tgene partner, which is a CGC due to the frame-shifted ORF. ATF7IP-PDGFRB seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF. ATF7IP-PDGFRB seems lost the major protein functional domain in Tgene partner, which is a kinase due to the frame-shifted ORF. |
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
Partner | Gene | GO ID | GO term | PubMed ID |
Hgene | ATF7IP | GO:0006306 | DNA methylation | 12665582 |
Hgene | ATF7IP | GO:0045892 | negative regulation of transcription, DNA-templated | 12665582 |
Hgene | ATF7IP | GO:0045893 | positive regulation of transcription, DNA-templated | 12665582 |
Hgene | ATF7IP | GO:0045898 | regulation of RNA polymerase II transcriptional preinitiation complex assembly | 12665582 |
Tgene | PDGFRB | GO:0007165 | signal transduction | 10821867 |
Tgene | PDGFRB | GO:0010863 | positive regulation of phospholipase C activity | 1653029 |
Tgene | PDGFRB | GO:0018108 | peptidyl-tyrosine phosphorylation | 1653029|2536956|2850496 |
Tgene | PDGFRB | GO:0030335 | positive regulation of cell migration | 17470632 |
Tgene | PDGFRB | GO:0032516 | positive regulation of phosphoprotein phosphatase activity | 7691811 |
Tgene | PDGFRB | GO:0038091 | positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway | 17470632 |
Tgene | PDGFRB | GO:0043552 | positive regulation of phosphatidylinositol 3-kinase activity | 1314164 |
Tgene | PDGFRB | GO:0046777 | protein autophosphorylation | 1314164|2536956|2850496 |
Tgene | PDGFRB | GO:0048008 | platelet-derived growth factor receptor signaling pathway | 1314164|2536956 |
Tgene | PDGFRB | GO:0060326 | cell chemotaxis | 2554309|17991872 |
Fusion gene breakpoints across ATF7IP (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
Fusion gene breakpoints across PDGFRB (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
Fusion gene information * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
ChimerKB4 | . | . | ATF7IP | chr12 | 14613428 | + | PDGFRB | chr5 | 14613428 | - |
ChimerKB4 | . | . | ATF7IP | chr12 | 14633936 | + | PDGFRB | chr5 | 14633936 | - |
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Fusion Gene ORF analysis for ATF7IP-PDGFRB |
Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
intron-intron | ENST00000261168 | ENST00000261799 | ATF7IP | chr12 | 14613428 | + | PDGFRB | chr5 | 14613428 | - |
intron-intron | ENST00000261168 | ENST00000261799 | ATF7IP | chr12 | 14633936 | + | PDGFRB | chr5 | 14633936 | - |
intron-intron | ENST00000261168 | ENST00000523456 | ATF7IP | chr12 | 14613428 | + | PDGFRB | chr5 | 14613428 | - |
intron-intron | ENST00000261168 | ENST00000523456 | ATF7IP | chr12 | 14633936 | + | PDGFRB | chr5 | 14633936 | - |
intron-intron | ENST00000536444 | ENST00000261799 | ATF7IP | chr12 | 14613428 | + | PDGFRB | chr5 | 14613428 | - |
intron-intron | ENST00000536444 | ENST00000261799 | ATF7IP | chr12 | 14633936 | + | PDGFRB | chr5 | 14633936 | - |
intron-intron | ENST00000536444 | ENST00000523456 | ATF7IP | chr12 | 14613428 | + | PDGFRB | chr5 | 14613428 | - |
intron-intron | ENST00000536444 | ENST00000523456 | ATF7IP | chr12 | 14633936 | + | PDGFRB | chr5 | 14633936 | - |
intron-intron | ENST00000540793 | ENST00000261799 | ATF7IP | chr12 | 14613428 | + | PDGFRB | chr5 | 14613428 | - |
intron-intron | ENST00000540793 | ENST00000261799 | ATF7IP | chr12 | 14633936 | + | PDGFRB | chr5 | 14633936 | - |
intron-intron | ENST00000540793 | ENST00000523456 | ATF7IP | chr12 | 14613428 | + | PDGFRB | chr5 | 14613428 | - |
intron-intron | ENST00000540793 | ENST00000523456 | ATF7IP | chr12 | 14633936 | + | PDGFRB | chr5 | 14633936 | - |
intron-intron | ENST00000541654 | ENST00000261799 | ATF7IP | chr12 | 14613428 | + | PDGFRB | chr5 | 14613428 | - |
intron-intron | ENST00000541654 | ENST00000261799 | ATF7IP | chr12 | 14633936 | + | PDGFRB | chr5 | 14633936 | - |
intron-intron | ENST00000541654 | ENST00000523456 | ATF7IP | chr12 | 14613428 | + | PDGFRB | chr5 | 14613428 | - |
intron-intron | ENST00000541654 | ENST00000523456 | ATF7IP | chr12 | 14633936 | + | PDGFRB | chr5 | 14633936 | - |
intron-intron | ENST00000543189 | ENST00000261799 | ATF7IP | chr12 | 14613428 | + | PDGFRB | chr5 | 14613428 | - |
intron-intron | ENST00000543189 | ENST00000261799 | ATF7IP | chr12 | 14633936 | + | PDGFRB | chr5 | 14633936 | - |
intron-intron | ENST00000543189 | ENST00000523456 | ATF7IP | chr12 | 14613428 | + | PDGFRB | chr5 | 14613428 | - |
intron-intron | ENST00000543189 | ENST00000523456 | ATF7IP | chr12 | 14633936 | + | PDGFRB | chr5 | 14633936 | - |
intron-intron | ENST00000544627 | ENST00000261799 | ATF7IP | chr12 | 14613428 | + | PDGFRB | chr5 | 14613428 | - |
intron-intron | ENST00000544627 | ENST00000261799 | ATF7IP | chr12 | 14633936 | + | PDGFRB | chr5 | 14633936 | - |
intron-intron | ENST00000544627 | ENST00000523456 | ATF7IP | chr12 | 14613428 | + | PDGFRB | chr5 | 14613428 | - |
intron-intron | ENST00000544627 | ENST00000523456 | ATF7IP | chr12 | 14633936 | + | PDGFRB | chr5 | 14633936 | - |
ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
ENST00000261168 | ENST00000261799 | ATF7IP | chr12 | 14634119 | + | PDGFRB | chr5 | 149506177 | - | 0.001302262 | 0.99869776 |
ENST00000536444 | ENST00000261799 | ATF7IP | chr12 | 14634119 | + | PDGFRB | chr5 | 149506177 | - | 0.001150028 | 0.99885 |
ENST00000544627 | ENST00000261799 | ATF7IP | chr12 | 14634119 | + | PDGFRB | chr5 | 149506177 | - | 0.001398285 | 0.99860173 |
ENST00000540793 | ENST00000261799 | ATF7IP | chr12 | 14634119 | + | PDGFRB | chr5 | 149506177 | - | 0.001135758 | 0.9988643 |
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Fusion Genomic Features for ATF7IP-PDGFRB |
FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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Fusion Protein Features for ATF7IP-PDGFRB |
Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr12:14634119/chr5:149506177) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
Main function of each fusion partner protein. (from UniProt) |
Hgene | Tgene |
. | PDGFRB |
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. | FUNCTION: Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. Plays a role in the migration of vascular smooth muscle cells and the formation of neointima at vascular injury sites. Required for normal development of the cardiovascular system. Required for normal recruitment of pericytes (mesangial cells) in the kidney glomerulus, and for normal formation of a branched network of capillaries in kidney glomeruli. Promotes rearrangement of the actin cytoskeleton and the formation of membrane ruffles. Binding of its cognate ligands - homodimeric PDGFB, heterodimers formed by PDGFA and PDGFB or homodimeric PDGFD -leads to the activation of several signaling cascades; the response depends on the nature of the bound ligand and is modulated by the formation of heterodimers between PDGFRA and PDGFRB. Phosphorylates PLCG1, PIK3R1, PTPN11, RASA1/GAP, CBL, SHC1 and NCK1. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate, mobilization of cytosolic Ca(2+) and the activation of protein kinase C. Phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, leads to the activation of the AKT1 signaling pathway. Phosphorylation of SHC1, or of the C-terminus of PTPN11, creates a binding site for GRB2, resulting in the activation of HRAS, RAF1 and down-stream MAP kinases, including MAPK1/ERK2 and/or MAPK3/ERK1. Promotes phosphorylation and activation of SRC family kinases. Promotes phosphorylation of PDCD6IP/ALIX and STAM. Receptor signaling is down-regulated by protein phosphatases that dephosphorylate the receptor and its down-stream effectors, and by rapid internalization of the activated receptor. {ECO:0000269|PubMed:11297552, ECO:0000269|PubMed:11331881, ECO:0000269|PubMed:1314164, ECO:0000269|PubMed:1396585, ECO:0000269|PubMed:1653029, ECO:0000269|PubMed:1709159, ECO:0000269|PubMed:1846866, ECO:0000269|PubMed:20494825, ECO:0000269|PubMed:20529858, ECO:0000269|PubMed:21098708, ECO:0000269|PubMed:21679854, ECO:0000269|PubMed:21733313, ECO:0000269|PubMed:2554309, ECO:0000269|PubMed:26599395, ECO:0000269|PubMed:2835772, ECO:0000269|PubMed:2850496, ECO:0000269|PubMed:7685273, ECO:0000269|PubMed:7691811, ECO:0000269|PubMed:7692233, ECO:0000269|PubMed:8195171}. |
Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
- In-frame and retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
Hgene | ATF7IP | chr12:14634119 | chr5:149506177 | ENST00000261168 | + | 13 | 15 | 617_665 | 1093 | 1271.0 | Coiled coil | Ontology_term=ECO:0000255 |
Hgene | ATF7IP | chr12:14634119 | chr5:149506177 | ENST00000540793 | + | 12 | 14 | 617_665 | 1093 | 1271.0 | Coiled coil | Ontology_term=ECO:0000255 |
Hgene | ATF7IP | chr12:14634119 | chr5:149506177 | ENST00000261168 | + | 13 | 15 | 349_580 | 1093 | 1271.0 | Compositional bias | Note=Glu-rich |
Hgene | ATF7IP | chr12:14634119 | chr5:149506177 | ENST00000540793 | + | 12 | 14 | 349_580 | 1093 | 1271.0 | Compositional bias | Note=Glu-rich |
Hgene | ATF7IP | chr12:14634119 | chr5:149506177 | ENST00000261168 | + | 13 | 15 | 553_571 | 1093 | 1271.0 | Motif | Nuclear localization signal |
Hgene | ATF7IP | chr12:14634119 | chr5:149506177 | ENST00000540793 | + | 12 | 14 | 553_571 | 1093 | 1271.0 | Motif | Nuclear localization signal |
Tgene | PDGFRB | chr12:14634119 | chr5:149506177 | ENST00000261799 | 9 | 23 | 600_962 | 526 | 1107.0 | Domain | Protein kinase | |
Tgene | PDGFRB | chr12:14634119 | chr5:149506177 | ENST00000261799 | 9 | 23 | 606_614 | 526 | 1107.0 | Nucleotide binding | ATP | |
Tgene | PDGFRB | chr12:14634119 | chr5:149506177 | ENST00000261799 | 9 | 23 | 554_1106 | 526 | 1107.0 | Topological domain | Cytoplasmic | |
Tgene | PDGFRB | chr12:14634119 | chr5:149506177 | ENST00000261799 | 9 | 23 | 533_553 | 526 | 1107.0 | Transmembrane | Helical |
- In-frame and not-retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
Hgene | ATF7IP | chr12:14634119 | chr5:149506177 | ENST00000543189 | + | 1 | 13 | 617_665 | 0 | 1106.0 | Coiled coil | Ontology_term=ECO:0000255 |
Hgene | ATF7IP | chr12:14634119 | chr5:149506177 | ENST00000543189 | + | 1 | 13 | 349_580 | 0 | 1106.0 | Compositional bias | Note=Glu-rich |
Hgene | ATF7IP | chr12:14634119 | chr5:149506177 | ENST00000261168 | + | 13 | 15 | 1160_1270 | 1093 | 1271.0 | Domain | Fibronectin type-III |
Hgene | ATF7IP | chr12:14634119 | chr5:149506177 | ENST00000540793 | + | 12 | 14 | 1160_1270 | 1093 | 1271.0 | Domain | Fibronectin type-III |
Hgene | ATF7IP | chr12:14634119 | chr5:149506177 | ENST00000543189 | + | 1 | 13 | 1160_1270 | 0 | 1106.0 | Domain | Fibronectin type-III |
Hgene | ATF7IP | chr12:14634119 | chr5:149506177 | ENST00000543189 | + | 1 | 13 | 553_571 | 0 | 1106.0 | Motif | Nuclear localization signal |
Tgene | PDGFRB | chr12:14634119 | chr5:149506177 | ENST00000261799 | 9 | 23 | 129_210 | 526 | 1107.0 | Domain | Note=Ig-like C2-type 2 | |
Tgene | PDGFRB | chr12:14634119 | chr5:149506177 | ENST00000261799 | 9 | 23 | 214_309 | 526 | 1107.0 | Domain | Note=Ig-like C2-type 3 | |
Tgene | PDGFRB | chr12:14634119 | chr5:149506177 | ENST00000261799 | 9 | 23 | 331_403 | 526 | 1107.0 | Domain | Note=Ig-like C2-type 4 | |
Tgene | PDGFRB | chr12:14634119 | chr5:149506177 | ENST00000261799 | 9 | 23 | 33_120 | 526 | 1107.0 | Domain | Note=Ig-like C2-type 1 | |
Tgene | PDGFRB | chr12:14634119 | chr5:149506177 | ENST00000261799 | 9 | 23 | 416_524 | 526 | 1107.0 | Domain | Note=Ig-like C2-type 5 | |
Tgene | PDGFRB | chr12:14634119 | chr5:149506177 | ENST00000261799 | 9 | 23 | 33_532 | 526 | 1107.0 | Topological domain | Extracellular |
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Fusion Gene Sequence for ATF7IP-PDGFRB |
For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
>7486_7486_1_ATF7IP-PDGFRB_ATF7IP_chr12_14634119_ENST00000261168_PDGFRB_chr5_149506177_ENST00000261799_length(transcript)=7101nt_BP=3433nt GAATCTGCGGAGGCGGCGGCGGTGGCAGCGGCGGCGCGGCGACTGAAGCGCGCGAAAAGCTGAGGCGGCAACGTCGGGGACGGCTGCGCG GGACGGCTCTGTAGGAAGGAACTTGGTTCCCCCTCCCTCAGCTTCCGCCCCAAAAGATTCAGAATGGACAGTTTAGAAGAACCTCAGAAA AAAGTCTTTAAGGCTCGAAAAACGATGAGAGTGAGTGATCGTCAGCAACTTGAAGCAGTGTACAAGGTCAAAGAAGAACTGTTGAAAACT GATGTCAAGCTGTTAAATGGCAACCATGAAAATGGAGATTTGGACCCAACCTCACCTTTGGAAAACATGGATTACATTAAAGACAAGGAA GAGGTGAATGGCATTGAAGAGATTTGTTTTGATCCTGAAGGAAGTAAAGCAGAATGGAAGGAAACACCCTGTATCCTAAGTGTTAATGTA AAAAACAAGCAGGATGATGATTTAAATTGTGAACCTTTGTCTCCCCATAATATAACTCCAGAACCAGTCTCTAAACTGCCTGCTGAACCA GTTTCTGGTGATCCAGCCCCTGGTGATCTGGATGCCGGAGATCCAGCCTCCGGAGTACTGGCCTCTGGTGATTCCACCTCTGGTGATCCC ACCTCTAGCGAGCCCTCCTCTAGTGATGCTGCCTCTGGTGATGCAACCTCTGGTGATGCCCCTTCTGGTGATGTGTCCCCTGGTGATGCC ACCTCTGGTGATGCCACTGCTGATGATCTCTCCTCTGGTGATCCCACCTCTAGTGATCCCATCCCAGGTGAACCGGTCCCTGTTGAACCC ATTTCTGGTGATTGTGCCGCTGATGATATAGCCTCTAGTGAAATAACTTCTGTTGATCTGGCTTCTGGAGCACCAGCTTCCACTGATCCA GCCTCTGATGATCTGGCCTCTGGTGATCTATCCTCTAGTGAACTGGCCTCTGATGATCTGGCCACTGGTGAACTGGCCTCTGATGAGCTG ACTTCTGAATCAACCTTTGATCGTACCTTTGAACCAAAGTCTGTACCAGTTTGTGAACCAGTTCCTGAAATTGACAATATAGAACCAAGT AGCAATAAAGATGATGATTTTCTTGAAAAAAATGGAGCTGATGAAAAATTAGAGCAAATTCAGAGTAAAGACTCATTGGATGAGAAAAAT AAAGCTGATAATAATATTGATGCTAATGAAGAAACTCTAGAAACAGATGATACAACTATTTGTTCAGATCGACCTCCTGAAAATGAAAAG AAGGTAGAGGAAGATATTATCACAGAGCTTGCTCTTGGAGAAGATGCTATATCTAGCAGTATGGAAATTGACCAAGGTGAAAAGAATGAA GATGAAACTTCTGCAGATCTTGTAGAAACGATTAATGAAAATGTTATTGAAGATAACAAAAGTGAGAATATCTTAGAAAATACAGACTCT ATGGAGACAGATGAAATCATTCCTATTTTGGAAAAGCTTGCACCTTCTGAGGATGAACTTACTTGCTTTTCTAAAACATCTCTCCTTCCA ATCGATGAGACAAATCCAGATTTGGAAGAGAAAATGGAAAGTTCTTTTGGTTCACCATCTAAACAAGAAAGTAGTGAGAGTTTGCCAAAA GAAGCCTTTCTGGTCCTCTCTGATGAAGAGGATATTTCGGGTGAAAAAGATGAGTCTGAAGTTATATCGCAAAATGAAACGTGCTCTCCA GCAGAAGTAGAAAGTAATGAAAAGGACAACAAACCTGAGGAAGAAGAGCAAGTAATACATGAAGATGATGAAAGACCTTCTGAGAAAAAT GAATTTTCTAGACGAAAACGTTCTAAATCAGAAGACATGGACAATGTACAGTCTAAACGTCGTCGATATATGGAAGAAGAATATGAGGCA GAATTTCAAGTAAAGATTACAGCCAAAGGAGACATTAACCAGAAACTTCAAAAGGTTATACAGTGGTTGCTGGAAGAAAAATTGTGTGCG CTGCAGTGTGCTGTATTTGATAAGACTTTGGCAGAATTGAAAACACGAGTGGAAAAGATTGAATGTAACAAGAGGCATAAAACAGTTCTC ACTGAACTACAGGCCAAGATAGCCAGGTTAACCAAACGCTTTGAAGCAGCCAAAGAAGATCTTAAGAAAAGACATGAACATCCACCCAAC CCACCAGTATCACCAGGAAAAACTGTAAATGATGTCAACAGCAATAATAACATGTCTTACAGAAATGCAGGCACAGTGAGACAGATGCTG GAGTCCAAAAGAAATGTAAGCGAGAGTGCACCACCATCCTTTCAAACTCCTGTGAATACAGTATCTTCAACCAATCTTGTCACTCCTCCA GCAGTTGTCAGTAGTCAACCTAAATTGCAGACTCCAGTGACTTCGGGTTCCCTCACAGCAACGTCAGTTCTTCCTGCACCCAATACAGCT ACTGTAGTTGCTACTACTCAGGTGCCTAGTGGAAATCCCCAGCCTACAATCTCTTTACAGCCTTTGCCAGTGATTTTGCATGTACCTGTT GCAGTATCCTCCCAGCCTCAGCTTCTACAGAGCCATCCAGGGACTTTGGTGACTAATCAACCATCTGGCAATGTTGAATTCATTTCTGTG CAAAGCCCACCTACAGTGAGTGGTCTTACCAAAAATCCAGTATCCTTGCCATCCTTGCCAAATCCCACTAAACCAAACAACGTTCCTTCT GTGCCCAGTCCTAGTATTCAAAGGAACCCTACTGCCAGTGCTGCACCATTGGGAACAACACTTGCTGTGCAGGCTGTTCCAACAGCACAC TCTATTGTACAAGCCACAAGGACTTCTTTACCCACAGTGGGCCCATCAGGACTCTATAGTCCATCAACTAATCGAGGTCCTATACAGATG AAAATTCCAATTTCTGCATTTAGTACTTCGTCTGCTGCAGAACAGAACAGCAATACCACCCCAAGAATTGAAAACCAGACAAACAAAACA ATAGATGCTTCTGTCAGTAAGAAAGCAGCTGATAGCACATCACAGTGTGGAAAAGCCACTGGCAGTGATTCAAGTGGTGTCATTGATCTC ACAATGGATGATGAAGAGAGTGGAGCTTCACAAGACCCCAAAAAACTAAATCACACTCCTGTATCAACCATGAGTTCTTCTCAGCCTGTG TCACGACCATTGCAACCCATACAACCAGCACCGCCTCTTCAACCATCTGGGGTGCCAACAAGTGGACCATCTCAGACCACCATACACTTA CTACCTACAGCTCCAACTACCGTGAATGTAACACATCGTCCAGTAACTCAGGTGACCACAAGACTCCCTGTACCAAGAGCTCCTGCAAAC CACCAGGTGGTTTATACAACTCTTCCTGCACCACCAGCTCAGGCTCCCTTGCGAGGAACTGTTATGCAGGCTCCTGCTGTTCGGCAGGTC AATCCCCAAAATACCTTGCCCTTTAAGGTGGTGGTGATCTCAGCCATCCTGGCCCTGGTGGTGCTCACCATCATCTCCCTTATCATCCTC ATCATGCTTTGGCAGAAGAAGCCACGTTACGAGATCCGATGGAAGGTGATTGAGTCTGTGAGCTCTGACGGCCATGAGTACATCTACGTG GACCCCATGCAGCTGCCCTATGACTCCACGTGGGAGCTGCCGCGGGACCAGCTTGTGCTGGGACGCACCCTCGGCTCTGGGGCCTTTGGG CAGGTGGTGGAGGCCACGGCTCATGGCCTGAGCCATTCTCAGGCCACGATGAAAGTGGCCGTCAAGATGCTTAAATCCACAGCCCGCAGC AGTGAGAAGCAAGCCCTTATGTCGGAGCTGAAGATCATGAGTCACCTTGGGCCCCACCTGAACGTGGTCAACCTGTTGGGGGCCTGCACC AAAGGAGGACCCATCTATATCATCACTGAGTACTGCCGCTACGGAGACCTGGTGGACTACCTGCACCGCAACAAACACACCTTCCTGCAG CACCACTCCGACAAGCGCCGCCCGCCCAGCGCGGAGCTCTACAGCAATGCTCTGCCCGTTGGGCTCCCCCTGCCCAGCCATGTGTCCTTG ACCGGGGAGAGCGACGGTGGCTACATGGACATGAGCAAGGACGAGTCGGTGGACTATGTGCCCATGCTGGACATGAAAGGAGACGTCAAA TATGCAGACATCGAGTCCTCCAACTACATGGCCCCTTACGATAACTACGTTCCCTCTGCCCCTGAGAGGACCTGCCGAGCAACTTTGATC AACGAGTCTCCAGTGCTAAGCTACATGGACCTCGTGGGCTTCAGCTACCAGGTGGCCAATGGCATGGAGTTTCTGGCCTCCAAGAACTGC GTCCACAGAGACCTGGCGGCTAGGAACGTGCTCATCTGTGAAGGCAAGCTGGTCAAGATCTGTGACTTTGGCCTGGCTCGAGACATCATG CGGGACTCGAATTACATCTCCAAAGGCAGCACCTTTTTGCCTTTAAAGTGGATGGCTCCGGAGAGCATCTTCAACAGCCTCTACACCACC CTGAGCGACGTGTGGTCCTTCGGGATCCTGCTCTGGGAGATCTTCACCTTGGGTGGCACCCCTTACCCAGAGCTGCCCATGAACGAGCAG TTCTACAATGCCATCAAACGGGGTTACCGCATGGCCCAGCCTGCCCATGCCTCCGACGAGATCTATGAGATCATGCAGAAGTGCTGGGAA GAGAAGTTTGAGATTCGGCCCCCCTTCTCCCAGCTGGTGCTGCTTCTCGAGAGACTGTTGGGCGAAGGTTACAAAAAGAAGTACCAGCAG GTGGATGAGGAGTTTCTGAGGAGTGACCACCCAGCCATCCTTCGGTCCCAGGCCCGCTTGCCTGGGTTCCATGGCCTCCGATCTCCCCTG GACACCAGCTCCGTCCTCTATACTGCCGTGCAGCCCAATGAGGGTGACAACGACTATATCATCCCCCTGCCTGACCCCAAACCCGAGGTT GCTGACGAGGGCCCACTGGAGGGTTCCCCCAGCCTAGCCAGCTCCACCCTGAATGAAGTCAACACCTCCTCAACCATCTCCTGTGACAGC CCCCTGGAGCCCCAGGACGAACCAGAGCCAGAGCCCCAGCTTGAGCTCCAGGTGGAGCCGGAGCCAGAGCTGGAACAGTTGCCGGATTCG GGGTGCCCTGCGCCTCGGGCGGAAGCAGAGGATAGCTTCCTGTAGGGGGCTGGCCCCTACCCTGCCCTGCCTGAAGCTCCCCCCCTGCCA GCACCCAGCATCTCCTGGCCTGGCCTGACCGGGCTTCCTGTCAGCCAGGCTGCCCTTATCAGCTGTCCCCTTCTGGAAGCTTTCTGCTCC TGACGTGTTGTGCCCCAAACCCTGGGGCTGGCTTAGGAGGCAAGAAAACTGCAGGGGCCGTGACCAGCCCTCTGCCTCCAGGGAGGCCAA CTGACTCTGAGCCAGGGTTCCCCCAGGGAACTCAGTTTTCCCATATGTAAAATGGGAAAGTTAGGCTTGATGACCCAGAATCTAGGATTC TCTCCCTGGCTGACAGGTGGGGAGACCGAATCCCTCCCTGGGAAGATTCTTGGAGTTACTGAGGTGGTAAATTAACTTTTTTCTGTTCAG CCAGCTACCCCTCAAGGAATCATAGCTCTCTCCTCGCACTTTTATCCACCCAGGAGCTAGGGAAGAGACCCTAGCCTCCCTGGCTGCTGG CTGAGCTAGGGCCTAGCCTTGAGCAGTGTTGCCTCATCCAGAAGAAAGCCAGTCTCCTCCCTATGATGCCAGTCCCTGCGTTCCCTGGCC CGAGCTGGTCTGGGGCCATTAGGCAGCCTAATTAATGCTGGAGGCTGAGCCAAGTACAGGACACCCCCAGCCTGCAGCCCTTGCCCAGGG CACTTGGAGCACACGCAGCCATAGCAAGTGCCTGTGTCCCTGTCCTTCAGGCCCATCAGTCCTGGGGCTTTTTCTTTATCACCCTCAGTC TTAATCCATCCACCAGAGTCTAGAAGGCCAGACGGGCCCCGCATCTGTGATGAGAATGTAAATGTGCCAGTGTGGAGTGGCCACGTGTGT GTGCCAGTATATGGCCCTGGCTCTGCATTGGACCTGCTATGAGGCTTTGGAGGAATCCCTCACCCTCTCTGGGCCTCAGTTTCCCCTTCA AAAAATGAATAAGTCGGACTTATTAACTCTGAGTGCCTTGCCAGCACTAACATTCTAGAGTATTCCAGGTGGTTGCACATTTGTCCAGAT GAAGCAAGGCCATATACCCTAAACTTCCATCCTGGGGGTCAGCTGGGCTCCTGGGAGATTCCAGATCACACATCACACTCTGGGGACTCA GGAACCATGCCCCTTCCCCAGGCCCCCAGCAAGTCTCAAGAACACAGCTGCACAGGCCTTGACTTAGAGTGACAGCCGGTGTCCTGGAAA GCCCCCAGCAGCTGCCCCAGGGACATGGGAAGACCACGGGACCTCTTTCACTACCCACGATGACCTCCGGGGGTATCCTGGGCAAAAGGG ACAAAGAGGGCAAATGAGATCACCTCCTGCAGCCCACCACTCCAGCACCTGTGCCGAGGTCTGCGTCGAAGACAGAATGGACAGTGAGGA CAGTTATGTCTTGTAAAAGACAAGAAGCTTCAGATGGGTACCCCAAGAAGGATGTGAGAGGTGGGCGCTTTGGAGGTTTGCCCCTCACCC ACCAGCTGCCCCATCCCTGAGGCAGCGCTCCATGGGGGTATGGTTTTGTCACTGCCCAGACCTAGCAGTGACATCTCATTGTCCCCAGCC CAGTGGGCATTGGAGGTGCCAGGGGAGTCAGGGTTGTAGCCAAGACGCCCCCGCACGGGGAGGGTTGGGAAGGGGGTGCAGGAAGCTCAA CCCCTCTGGGCACCAACCCTGCATTGCAGGTTGGCACCTTACTTCCCTGGGATCCCCAGAGTTGGTCCAAGGAGGGAGAGTGGGTTCTCA ATACGGTACCAAAGATATAATCACCTAGGTTTACAAATATTTTTAGGACTCACGTTAACTCACATTTATACAGCAGAAATGCTATTTTGT >7486_7486_1_ATF7IP-PDGFRB_ATF7IP_chr12_14634119_ENST00000261168_PDGFRB_chr5_149506177_ENST00000261799_length(amino acids)=1673AA_BP=1094 MDSLEEPQKKVFKARKTMRVSDRQQLEAVYKVKEELLKTDVKLLNGNHENGDLDPTSPLENMDYIKDKEEVNGIEEICFDPEGSKAEWKE TPCILSVNVKNKQDDDLNCEPLSPHNITPEPVSKLPAEPVSGDPAPGDLDAGDPASGVLASGDSTSGDPTSSEPSSSDAASGDATSGDAP SGDVSPGDATSGDATADDLSSGDPTSSDPIPGEPVPVEPISGDCAADDIASSEITSVDLASGAPASTDPASDDLASGDLSSSELASDDLA TGELASDELTSESTFDRTFEPKSVPVCEPVPEIDNIEPSSNKDDDFLEKNGADEKLEQIQSKDSLDEKNKADNNIDANEETLETDDTTIC SDRPPENEKKVEEDIITELALGEDAISSSMEIDQGEKNEDETSADLVETINENVIEDNKSENILENTDSMETDEIIPILEKLAPSEDELT CFSKTSLLPIDETNPDLEEKMESSFGSPSKQESSESLPKEAFLVLSDEEDISGEKDESEVISQNETCSPAEVESNEKDNKPEEEEQVIHE DDERPSEKNEFSRRKRSKSEDMDNVQSKRRRYMEEEYEAEFQVKITAKGDINQKLQKVIQWLLEEKLCALQCAVFDKTLAELKTRVEKIE CNKRHKTVLTELQAKIARLTKRFEAAKEDLKKRHEHPPNPPVSPGKTVNDVNSNNNMSYRNAGTVRQMLESKRNVSESAPPSFQTPVNTV SSTNLVTPPAVVSSQPKLQTPVTSGSLTATSVLPAPNTATVVATTQVPSGNPQPTISLQPLPVILHVPVAVSSQPQLLQSHPGTLVTNQP SGNVEFISVQSPPTVSGLTKNPVSLPSLPNPTKPNNVPSVPSPSIQRNPTASAAPLGTTLAVQAVPTAHSIVQATRTSLPTVGPSGLYSP STNRGPIQMKIPISAFSTSSAAEQNSNTTPRIENQTNKTIDASVSKKAADSTSQCGKATGSDSSGVIDLTMDDEESGASQDPKKLNHTPV STMSSSQPVSRPLQPIQPAPPLQPSGVPTSGPSQTTIHLLPTAPTTVNVTHRPVTQVTTRLPVPRAPANHQVVYTTLPAPPAQAPLRGTV MQAPAVRQVNPQNTLPFKVVVISAILALVVLTIISLIILIMLWQKKPRYEIRWKVIESVSSDGHEYIYVDPMQLPYDSTWELPRDQLVLG RTLGSGAFGQVVEATAHGLSHSQATMKVAVKMLKSTARSSEKQALMSELKIMSHLGPHLNVVNLLGACTKGGPIYIITEYCRYGDLVDYL HRNKHTFLQHHSDKRRPPSAELYSNALPVGLPLPSHVSLTGESDGGYMDMSKDESVDYVPMLDMKGDVKYADIESSNYMAPYDNYVPSAP ERTCRATLINESPVLSYMDLVGFSYQVANGMEFLASKNCVHRDLAARNVLICEGKLVKICDFGLARDIMRDSNYISKGSTFLPLKWMAPE SIFNSLYTTLSDVWSFGILLWEIFTLGGTPYPELPMNEQFYNAIKRGYRMAQPAHASDEIYEIMQKCWEEKFEIRPPFSQLVLLLERLLG EGYKKKYQQVDEEFLRSDHPAILRSQARLPGFHGLRSPLDTSSVLYTAVQPNEGDNDYIIPLPDPKPEVADEGPLEGSPSLASSTLNEVN -------------------------------------------------------------- >7486_7486_2_ATF7IP-PDGFRB_ATF7IP_chr12_14634119_ENST00000536444_PDGFRB_chr5_149506177_ENST00000261799_length(transcript)=7051nt_BP=3383nt GCGCGCGAAAAGCTGAGGCGGCAACGTCGGGGACGGCTGCGCGGGACGGCTCTGTAGGAAGGAACTTGGTTCCCCCTCCCTCAGCTTCCG CCCCAAAAGATTCAGAATGGACAGTTTAGAAGAACCTCAGAAAAAAGTCTTTAAGGCTCGAAAAACGATGAGAGTGAGTGATCGTCAGCA ACTTGAAGCAGTGTACAAGGTCAAAGAAGAACTGTTGAAAACTGATGTCAAGCTGTTAAATGGCAACCATGAAAATGGAGATTTGGACCC AACCTCACCTTTGGAAAACATGGATTACATTAAAGACAAGGAAGAGGTGAATGGCATTGAAGAGATTTGTTTTGATCCTGAAGGAAGTAA AGCAGAATGGAAGGAAACACCCTGTATCCTAAGTGTTAATGTAAAAAACAAGCAGGATGATGATTTAAATTGTGAACCTTTGTCTCCCCA TAATATAACTCCAGAACCAGTCTCTAAACTGCCTGCTGAACCAGTTTCTGGTGATCCAGCCCCTGGTGATCTGGATGCCGGAGATCCAGC CTCCGGAGTACTGGCCTCTGGTGATTCCACCTCTGGTGATCCCACCTCTAGCGAGCCCTCCTCTAGTGATGCTGCCTCTGGTGATGCAAC CTCTGGTGATGCCCCTTCTGGTGATGTGTCCCCTGGTGATGCCACCTCTGGTGATGCCACTGCTGATGATCTCTCCTCTGGTGATCCCAC CTCTAGTGATCCCATCCCAGGTGAACCGGTCCCTGTTGAACCCATTTCTGGTGATTGTGCCGCTGATGATATAGCCTCTAGTGAAATAAC TTCTGTTGATCTGGCTTCTGGAGCACCAGCTTCCACTGATCCAGCCTCTGATGATCTGGCCTCTGGTGATCTATCCTCTAGTGAACTGGC CTCTGATGATCTGGCCACTGGTGAACTGGCCTCTGATGAGCTGACTTCTGAATCAACCTTTGATCGTACCTTTGAACCAAAGTCTGTACC AGTTTGTGAACCAGTTCCTGAAATTGACAATATAGAACCAAGTAGCAATAAAGATGATGATTTTCTTGAAAAAAATGGAGCTGATGAAAA ATTAGAGCAAATTCAGAGTAAAGACTCATTGGATGAGAAAAATAAAGCTGATAATAATATTGATGCTAATGAAGAAACTCTAGAAACAGA TGATACAACTATTTGTTCAGATCGACCTCCTGAAAATGAAAAGAAGGTAGAGGAAGATATTATCACAGAGCTTGCTCTTGGAGAAGATGC TATATCTAGCAGTATGGAAATTGACCAAGGTGAAAAGAATGAAGATGAAACTTCTGCAGATCTTGTAGAAACGATTAATGAAAATGTTAT TGAAGATAACAAAAGTGAGAATATCTTAGAAAATACAGACTCTATGGAGACAGATGAAATCATTCCTATTTTGGAAAAGCTTGCACCTTC TGAGGATGAACTTACTTGCTTTTCTAAAACATCTCTCCTTCCAATCGATGAGACAAATCCAGATTTGGAAGAGAAAATGGAAAGTTCTTT TGGTTCACCATCTAAACAAGAAAGTAGTGAGAGTTTGCCAAAAGAAGCCTTTCTGGTCCTCTCTGATGAAGAGGATATTTCGGGTGAAAA AGATGAGTCTGAAGTTATATCGCAAAATGAAACGTGCTCTCCAGAAGTAGAAAGTAATGAAAAGGACAACAAACCTGAGGAAGAAGAGCA AGTAATACATGAAGATGATGAAAGACCTTCTGAGAAAAATGAATTTTCTAGACGAAAACGTTCTAAATCAGAAGACATGGACAATGTACA GTCTAAACGTCGTCGATATATGGAAGAAGAATATGAGGCAGAATTTCAAGTAAAGATTACAGCCAAAGGAGACATTAACCAGAAACTTCA AAAGGTTATACAGTGGTTGCTGGAAGAAAAATTGTGTGCGCTGCAGTGTGCTGTATTTGATAAGACTTTGGCAGAATTGAAAACACGAGT GGAAAAGATTGAATGTAACAAGAGGCATAAAACAGTTCTCACTGAACTACAGGCCAAGATAGCCAGGTTAACCAAACGCTTTGAAGCAGC CAAAGAAGATCTTAAGAAAAGACATGAACATCCACCCAACCCACCAGTATCACCAGGAAAAACTGTAAATGATGTCAACAGCAATAATAA CATGTCTTACAGAAATGCAGGCACAGTGAGACAGATGCTGGAGTCCAAAAGAAATGTAAGCGAGAGTGCACCACCATCCTTTCAAACTCC TGTGAATACAGTATCTTCAACCAATCTTGTCACTCCTCCAGCAGTTGTCAGTAGTCAACCTAAATTGCAGACTCCAGTGACTTCGGGTTC CCTCACAGCAACGTCAGTTCTTCCTGCACCCAATACAGCTACTGTAGTTGCTACTACTCAGGTGCCTAGTGGAAATCCCCAGCCTACAAT CTCTTTACAGCCTTTGCCAGTGATTTTGCATGTACCTGTTGCAGTATCCTCCCAGCCTCAGCTTCTACAGAGCCATCCAGGGACTTTGGT GACTAATCAACCATCTGGCAATGTTGAATTCATTTCTGTGCAAAGCCCACCTACAGTGAGTGGTCTTACCAAAAATCCAGTATCCTTGCC ATCCTTGCCAAATCCCACTAAACCAAACAACGTTCCTTCTGTGCCCAGTCCTAGTATTCAAAGGAACCCTACTGCCAGTGCTGCACCATT GGGAACAACACTTGCTGTGCAGGCTGTTCCAACAGCACACTCTATTGTACAAGCCACAAGGACTTCTTTACCCACAGTGGGCCCATCAGG ACTCTATAGTCCATCAACTAATCGAGGTCCTATACAGATGAAAATTCCAATTTCTGCATTTAGTACTTCGTCTGCTGCAGAACAGAACAG CAATACCACCCCAAGAATTGAAAACCAGACAAACAAAACAATAGATGCTTCTGTCAGTAAGAAAGCAGCTGATAGCACATCACAGTGTGG AAAAGCCACTGGCAGTGATTCAAGTGGTGTCATTGATCTCACAATGGATGATGAAGAGAGTGGAGCTTCACAAGACCCCAAAAAACTAAA TCACACTCCTGTATCAACCATGAGTTCTTCTCAGCCTGTGTCACGACCATTGCAACCCATACAACCAGCACCGCCTCTTCAACCATCTGG GGTGCCAACAAGTGGACCATCTCAGACCACCATACACTTACTACCTACAGCTCCAACTACCGTGAATGTAACACATCGTCCAGTAACTCA GGTGACCACAAGACTCCCTGTACCAAGAGCTCCTGCAAACCACCAGGTGGTTTATACAACTCTTCCTGCACCACCAGCTCAGGCTCCCTT GCGAGGAACTGTTATGCAGGCTCCTGCTGTTCGGCAGGTCAATCCCCAAAATACCTTGCCCTTTAAGGTGGTGGTGATCTCAGCCATCCT GGCCCTGGTGGTGCTCACCATCATCTCCCTTATCATCCTCATCATGCTTTGGCAGAAGAAGCCACGTTACGAGATCCGATGGAAGGTGAT TGAGTCTGTGAGCTCTGACGGCCATGAGTACATCTACGTGGACCCCATGCAGCTGCCCTATGACTCCACGTGGGAGCTGCCGCGGGACCA GCTTGTGCTGGGACGCACCCTCGGCTCTGGGGCCTTTGGGCAGGTGGTGGAGGCCACGGCTCATGGCCTGAGCCATTCTCAGGCCACGAT GAAAGTGGCCGTCAAGATGCTTAAATCCACAGCCCGCAGCAGTGAGAAGCAAGCCCTTATGTCGGAGCTGAAGATCATGAGTCACCTTGG GCCCCACCTGAACGTGGTCAACCTGTTGGGGGCCTGCACCAAAGGAGGACCCATCTATATCATCACTGAGTACTGCCGCTACGGAGACCT GGTGGACTACCTGCACCGCAACAAACACACCTTCCTGCAGCACCACTCCGACAAGCGCCGCCCGCCCAGCGCGGAGCTCTACAGCAATGC TCTGCCCGTTGGGCTCCCCCTGCCCAGCCATGTGTCCTTGACCGGGGAGAGCGACGGTGGCTACATGGACATGAGCAAGGACGAGTCGGT GGACTATGTGCCCATGCTGGACATGAAAGGAGACGTCAAATATGCAGACATCGAGTCCTCCAACTACATGGCCCCTTACGATAACTACGT TCCCTCTGCCCCTGAGAGGACCTGCCGAGCAACTTTGATCAACGAGTCTCCAGTGCTAAGCTACATGGACCTCGTGGGCTTCAGCTACCA GGTGGCCAATGGCATGGAGTTTCTGGCCTCCAAGAACTGCGTCCACAGAGACCTGGCGGCTAGGAACGTGCTCATCTGTGAAGGCAAGCT GGTCAAGATCTGTGACTTTGGCCTGGCTCGAGACATCATGCGGGACTCGAATTACATCTCCAAAGGCAGCACCTTTTTGCCTTTAAAGTG GATGGCTCCGGAGAGCATCTTCAACAGCCTCTACACCACCCTGAGCGACGTGTGGTCCTTCGGGATCCTGCTCTGGGAGATCTTCACCTT GGGTGGCACCCCTTACCCAGAGCTGCCCATGAACGAGCAGTTCTACAATGCCATCAAACGGGGTTACCGCATGGCCCAGCCTGCCCATGC CTCCGACGAGATCTATGAGATCATGCAGAAGTGCTGGGAAGAGAAGTTTGAGATTCGGCCCCCCTTCTCCCAGCTGGTGCTGCTTCTCGA GAGACTGTTGGGCGAAGGTTACAAAAAGAAGTACCAGCAGGTGGATGAGGAGTTTCTGAGGAGTGACCACCCAGCCATCCTTCGGTCCCA GGCCCGCTTGCCTGGGTTCCATGGCCTCCGATCTCCCCTGGACACCAGCTCCGTCCTCTATACTGCCGTGCAGCCCAATGAGGGTGACAA CGACTATATCATCCCCCTGCCTGACCCCAAACCCGAGGTTGCTGACGAGGGCCCACTGGAGGGTTCCCCCAGCCTAGCCAGCTCCACCCT GAATGAAGTCAACACCTCCTCAACCATCTCCTGTGACAGCCCCCTGGAGCCCCAGGACGAACCAGAGCCAGAGCCCCAGCTTGAGCTCCA GGTGGAGCCGGAGCCAGAGCTGGAACAGTTGCCGGATTCGGGGTGCCCTGCGCCTCGGGCGGAAGCAGAGGATAGCTTCCTGTAGGGGGC TGGCCCCTACCCTGCCCTGCCTGAAGCTCCCCCCCTGCCAGCACCCAGCATCTCCTGGCCTGGCCTGACCGGGCTTCCTGTCAGCCAGGC TGCCCTTATCAGCTGTCCCCTTCTGGAAGCTTTCTGCTCCTGACGTGTTGTGCCCCAAACCCTGGGGCTGGCTTAGGAGGCAAGAAAACT GCAGGGGCCGTGACCAGCCCTCTGCCTCCAGGGAGGCCAACTGACTCTGAGCCAGGGTTCCCCCAGGGAACTCAGTTTTCCCATATGTAA AATGGGAAAGTTAGGCTTGATGACCCAGAATCTAGGATTCTCTCCCTGGCTGACAGGTGGGGAGACCGAATCCCTCCCTGGGAAGATTCT TGGAGTTACTGAGGTGGTAAATTAACTTTTTTCTGTTCAGCCAGCTACCCCTCAAGGAATCATAGCTCTCTCCTCGCACTTTTATCCACC CAGGAGCTAGGGAAGAGACCCTAGCCTCCCTGGCTGCTGGCTGAGCTAGGGCCTAGCCTTGAGCAGTGTTGCCTCATCCAGAAGAAAGCC AGTCTCCTCCCTATGATGCCAGTCCCTGCGTTCCCTGGCCCGAGCTGGTCTGGGGCCATTAGGCAGCCTAATTAATGCTGGAGGCTGAGC CAAGTACAGGACACCCCCAGCCTGCAGCCCTTGCCCAGGGCACTTGGAGCACACGCAGCCATAGCAAGTGCCTGTGTCCCTGTCCTTCAG GCCCATCAGTCCTGGGGCTTTTTCTTTATCACCCTCAGTCTTAATCCATCCACCAGAGTCTAGAAGGCCAGACGGGCCCCGCATCTGTGA TGAGAATGTAAATGTGCCAGTGTGGAGTGGCCACGTGTGTGTGCCAGTATATGGCCCTGGCTCTGCATTGGACCTGCTATGAGGCTTTGG AGGAATCCCTCACCCTCTCTGGGCCTCAGTTTCCCCTTCAAAAAATGAATAAGTCGGACTTATTAACTCTGAGTGCCTTGCCAGCACTAA CATTCTAGAGTATTCCAGGTGGTTGCACATTTGTCCAGATGAAGCAAGGCCATATACCCTAAACTTCCATCCTGGGGGTCAGCTGGGCTC CTGGGAGATTCCAGATCACACATCACACTCTGGGGACTCAGGAACCATGCCCCTTCCCCAGGCCCCCAGCAAGTCTCAAGAACACAGCTG CACAGGCCTTGACTTAGAGTGACAGCCGGTGTCCTGGAAAGCCCCCAGCAGCTGCCCCAGGGACATGGGAAGACCACGGGACCTCTTTCA CTACCCACGATGACCTCCGGGGGTATCCTGGGCAAAAGGGACAAAGAGGGCAAATGAGATCACCTCCTGCAGCCCACCACTCCAGCACCT GTGCCGAGGTCTGCGTCGAAGACAGAATGGACAGTGAGGACAGTTATGTCTTGTAAAAGACAAGAAGCTTCAGATGGGTACCCCAAGAAG GATGTGAGAGGTGGGCGCTTTGGAGGTTTGCCCCTCACCCACCAGCTGCCCCATCCCTGAGGCAGCGCTCCATGGGGGTATGGTTTTGTC ACTGCCCAGACCTAGCAGTGACATCTCATTGTCCCCAGCCCAGTGGGCATTGGAGGTGCCAGGGGAGTCAGGGTTGTAGCCAAGACGCCC CCGCACGGGGAGGGTTGGGAAGGGGGTGCAGGAAGCTCAACCCCTCTGGGCACCAACCCTGCATTGCAGGTTGGCACCTTACTTCCCTGG GATCCCCAGAGTTGGTCCAAGGAGGGAGAGTGGGTTCTCAATACGGTACCAAAGATATAATCACCTAGGTTTACAAATATTTTTAGGACT CACGTTAACTCACATTTATACAGCAGAAATGCTATTTTGTATGCTGTTGAGTTTTTCTATCTGTGTACTTTTTTTTAAGGGAAAGATTTT >7486_7486_2_ATF7IP-PDGFRB_ATF7IP_chr12_14634119_ENST00000536444_PDGFRB_chr5_149506177_ENST00000261799_length(amino acids)=1672AA_BP=1093 MDSLEEPQKKVFKARKTMRVSDRQQLEAVYKVKEELLKTDVKLLNGNHENGDLDPTSPLENMDYIKDKEEVNGIEEICFDPEGSKAEWKE TPCILSVNVKNKQDDDLNCEPLSPHNITPEPVSKLPAEPVSGDPAPGDLDAGDPASGVLASGDSTSGDPTSSEPSSSDAASGDATSGDAP SGDVSPGDATSGDATADDLSSGDPTSSDPIPGEPVPVEPISGDCAADDIASSEITSVDLASGAPASTDPASDDLASGDLSSSELASDDLA TGELASDELTSESTFDRTFEPKSVPVCEPVPEIDNIEPSSNKDDDFLEKNGADEKLEQIQSKDSLDEKNKADNNIDANEETLETDDTTIC SDRPPENEKKVEEDIITELALGEDAISSSMEIDQGEKNEDETSADLVETINENVIEDNKSENILENTDSMETDEIIPILEKLAPSEDELT CFSKTSLLPIDETNPDLEEKMESSFGSPSKQESSESLPKEAFLVLSDEEDISGEKDESEVISQNETCSPEVESNEKDNKPEEEEQVIHED DERPSEKNEFSRRKRSKSEDMDNVQSKRRRYMEEEYEAEFQVKITAKGDINQKLQKVIQWLLEEKLCALQCAVFDKTLAELKTRVEKIEC NKRHKTVLTELQAKIARLTKRFEAAKEDLKKRHEHPPNPPVSPGKTVNDVNSNNNMSYRNAGTVRQMLESKRNVSESAPPSFQTPVNTVS STNLVTPPAVVSSQPKLQTPVTSGSLTATSVLPAPNTATVVATTQVPSGNPQPTISLQPLPVILHVPVAVSSQPQLLQSHPGTLVTNQPS GNVEFISVQSPPTVSGLTKNPVSLPSLPNPTKPNNVPSVPSPSIQRNPTASAAPLGTTLAVQAVPTAHSIVQATRTSLPTVGPSGLYSPS TNRGPIQMKIPISAFSTSSAAEQNSNTTPRIENQTNKTIDASVSKKAADSTSQCGKATGSDSSGVIDLTMDDEESGASQDPKKLNHTPVS TMSSSQPVSRPLQPIQPAPPLQPSGVPTSGPSQTTIHLLPTAPTTVNVTHRPVTQVTTRLPVPRAPANHQVVYTTLPAPPAQAPLRGTVM QAPAVRQVNPQNTLPFKVVVISAILALVVLTIISLIILIMLWQKKPRYEIRWKVIESVSSDGHEYIYVDPMQLPYDSTWELPRDQLVLGR TLGSGAFGQVVEATAHGLSHSQATMKVAVKMLKSTARSSEKQALMSELKIMSHLGPHLNVVNLLGACTKGGPIYIITEYCRYGDLVDYLH RNKHTFLQHHSDKRRPPSAELYSNALPVGLPLPSHVSLTGESDGGYMDMSKDESVDYVPMLDMKGDVKYADIESSNYMAPYDNYVPSAPE RTCRATLINESPVLSYMDLVGFSYQVANGMEFLASKNCVHRDLAARNVLICEGKLVKICDFGLARDIMRDSNYISKGSTFLPLKWMAPES IFNSLYTTLSDVWSFGILLWEIFTLGGTPYPELPMNEQFYNAIKRGYRMAQPAHASDEIYEIMQKCWEEKFEIRPPFSQLVLLLERLLGE GYKKKYQQVDEEFLRSDHPAILRSQARLPGFHGLRSPLDTSSVLYTAVQPNEGDNDYIIPLPDPKPEVADEGPLEGSPSLASSTLNEVNT -------------------------------------------------------------- >7486_7486_3_ATF7IP-PDGFRB_ATF7IP_chr12_14634119_ENST00000540793_PDGFRB_chr5_149506177_ENST00000261799_length(transcript)=7103nt_BP=3435nt TAGTATACAACAAGCAGTAGGTTTTCTATGTCTTAAACATTACATGAAATGTGCTGCTTGCATCTCTTCTAAGATCAATTTGTATTAAGT CTACAATTAGGTGGCTTCTGTTTCAGTTATTAAACTCTCTTTCTCTTTTTTCTTAAAGATTCAGAATGGACAGTTTAGAAGAACCTCAGA AAAAAGTCTTTAAGGCTCGAAAAACGATGAGAGTGAGTGATCGTCAGCAACTTGAAGCAGTGTACAAGGTCAAAGAAGAACTGTTGAAAA CTGATGTCAAGCTGTTAAATGGCAACCATGAAAATGGAGATTTGGACCCAACCTCACCTTTGGAAAACATGGATTACATTAAAGACAAGG AAGAGGTGAATGGCATTGAAGAGATTTGTTTTGATCCTGAAGGAAGTAAAGCAGAATGGAAGGAAACACCCTGTATCCTAAGTGTTAATG TAAAAAACAAGCAGGATGATGATTTAAATTGTGAACCTTTGTCTCCCCATAATATAACTCCAGAACCAGTCTCTAAACTGCCTGCTGAAC CAGTTTCTGGTGATCCAGCCCCTGGTGATCTGGATGCCGGAGATCCAGCCTCCGGAGTACTGGCCTCTGGTGATTCCACCTCTGGTGATC CCACCTCTAGCGAGCCCTCCTCTAGTGATGCTGCCTCTGGTGATGCAACCTCTGGTGATGCCCCTTCTGGTGATGTGTCCCCTGGTGATG CCACCTCTGGTGATGCCACTGCTGATGATCTCTCCTCTGGTGATCCCACCTCTAGTGATCCCATCCCAGGTGAACCGGTCCCTGTTGAAC CCATTTCTGGTGATTGTGCCGCTGATGATATAGCCTCTAGTGAAATAACTTCTGTTGATCTGGCTTCTGGAGCACCAGCTTCCACTGATC CAGCCTCTGATGATCTGGCCTCTGGTGATCTATCCTCTAGTGAACTGGCCTCTGATGATCTGGCCACTGGTGAACTGGCCTCTGATGAGC TGACTTCTGAATCAACCTTTGATCGTACCTTTGAACCAAAGTCTGTACCAGTTTGTGAACCAGTTCCTGAAATTGACAATATAGAACCAA GTAGCAATAAAGATGATGATTTTCTTGAAAAAAATGGAGCTGATGAAAAATTAGAGCAAATTCAGAGTAAAGACTCATTGGATGAGAAAA ATAAAGCTGATAATAATATTGATGCTAATGAAGAAACTCTAGAAACAGATGATACAACTATTTGTTCAGATCGACCTCCTGAAAATGAAA AGAAGGTAGAGGAAGATATTATCACAGAGCTTGCTCTTGGAGAAGATGCTATATCTAGCAGTATGGAAATTGACCAAGGTGAAAAGAATG AAGATGAAACTTCTGCAGATCTTGTAGAAACGATTAATGAAAATGTTATTGAAGATAACAAAAGTGAGAATATCTTAGAAAATACAGACT CTATGGAGACAGATGAAATCATTCCTATTTTGGAAAAGCTTGCACCTTCTGAGGATGAACTTACTTGCTTTTCTAAAACATCTCTCCTTC CAATCGATGAGACAAATCCAGATTTGGAAGAGAAAATGGAAAGTTCTTTTGGTTCACCATCTAAACAAGAAAGTAGTGAGAGTTTGCCAA AAGAAGCCTTTCTGGTCCTCTCTGATGAAGAGGATATTTCGGGTGAAAAAGATGAGTCTGAAGTTATATCGCAAAATGAAACGTGCTCTC CAGCAGAAGTAGAAAGTAATGAAAAGGACAACAAACCTGAGGAAGAAGAGCAAGTAATACATGAAGATGATGAAAGACCTTCTGAGAAAA ATGAATTTTCTAGACGAAAACGTTCTAAATCAGAAGACATGGACAATGTACAGTCTAAACGTCGTCGATATATGGAAGAAGAATATGAGG CAGAATTTCAAGTAAAGATTACAGCCAAAGGAGACATTAACCAGAAACTTCAAAAGGTTATACAGTGGTTGCTGGAAGAAAAATTGTGTG CGCTGCAGTGTGCTGTATTTGATAAGACTTTGGCAGAATTGAAAACACGAGTGGAAAAGATTGAATGTAACAAGAGGCATAAAACAGTTC TCACTGAACTACAGGCCAAGATAGCCAGGTTAACCAAACGCTTTGAAGCAGCCAAAGAAGATCTTAAGAAAAGACATGAACATCCACCCA ACCCACCAGTATCACCAGGAAAAACTGTAAATGATGTCAACAGCAATAATAACATGTCTTACAGAAATGCAGGCACAGTGAGACAGATGC TGGAGTCCAAAAGAAATGTAAGCGAGAGTGCACCACCATCCTTTCAAACTCCTGTGAATACAGTATCTTCAACCAATCTTGTCACTCCTC CAGCAGTTGTCAGTAGTCAACCTAAATTGCAGACTCCAGTGACTTCGGGTTCCCTCACAGCAACGTCAGTTCTTCCTGCACCCAATACAG CTACTGTAGTTGCTACTACTCAGGTGCCTAGTGGAAATCCCCAGCCTACAATCTCTTTACAGCCTTTGCCAGTGATTTTGCATGTACCTG TTGCAGTATCCTCCCAGCCTCAGCTTCTACAGAGCCATCCAGGGACTTTGGTGACTAATCAACCATCTGGCAATGTTGAATTCATTTCTG TGCAAAGCCCACCTACAGTGAGTGGTCTTACCAAAAATCCAGTATCCTTGCCATCCTTGCCAAATCCCACTAAACCAAACAACGTTCCTT CTGTGCCCAGTCCTAGTATTCAAAGGAACCCTACTGCCAGTGCTGCACCATTGGGAACAACACTTGCTGTGCAGGCTGTTCCAACAGCAC ACTCTATTGTACAAGCCACAAGGACTTCTTTACCCACAGTGGGCCCATCAGGACTCTATAGTCCATCAACTAATCGAGGTCCTATACAGA TGAAAATTCCAATTTCTGCATTTAGTACTTCGTCTGCTGCAGAACAGAACAGCAATACCACCCCAAGAATTGAAAACCAGACAAACAAAA CAATAGATGCTTCTGTCAGTAAGAAAGCAGCTGATAGCACATCACAGTGTGGAAAAGCCACTGGCAGTGATTCAAGTGGTGTCATTGATC TCACAATGGATGATGAAGAGAGTGGAGCTTCACAAGACCCCAAAAAACTAAATCACACTCCTGTATCAACCATGAGTTCTTCTCAGCCTG TGTCACGACCATTGCAACCCATACAACCAGCACCGCCTCTTCAACCATCTGGGGTGCCAACAAGTGGACCATCTCAGACCACCATACACT TACTACCTACAGCTCCAACTACCGTGAATGTAACACATCGTCCAGTAACTCAGGTGACCACAAGACTCCCTGTACCAAGAGCTCCTGCAA ACCACCAGGTGGTTTATACAACTCTTCCTGCACCACCAGCTCAGGCTCCCTTGCGAGGAACTGTTATGCAGGCTCCTGCTGTTCGGCAGG TCAATCCCCAAAATACCTTGCCCTTTAAGGTGGTGGTGATCTCAGCCATCCTGGCCCTGGTGGTGCTCACCATCATCTCCCTTATCATCC TCATCATGCTTTGGCAGAAGAAGCCACGTTACGAGATCCGATGGAAGGTGATTGAGTCTGTGAGCTCTGACGGCCATGAGTACATCTACG TGGACCCCATGCAGCTGCCCTATGACTCCACGTGGGAGCTGCCGCGGGACCAGCTTGTGCTGGGACGCACCCTCGGCTCTGGGGCCTTTG GGCAGGTGGTGGAGGCCACGGCTCATGGCCTGAGCCATTCTCAGGCCACGATGAAAGTGGCCGTCAAGATGCTTAAATCCACAGCCCGCA GCAGTGAGAAGCAAGCCCTTATGTCGGAGCTGAAGATCATGAGTCACCTTGGGCCCCACCTGAACGTGGTCAACCTGTTGGGGGCCTGCA CCAAAGGAGGACCCATCTATATCATCACTGAGTACTGCCGCTACGGAGACCTGGTGGACTACCTGCACCGCAACAAACACACCTTCCTGC AGCACCACTCCGACAAGCGCCGCCCGCCCAGCGCGGAGCTCTACAGCAATGCTCTGCCCGTTGGGCTCCCCCTGCCCAGCCATGTGTCCT TGACCGGGGAGAGCGACGGTGGCTACATGGACATGAGCAAGGACGAGTCGGTGGACTATGTGCCCATGCTGGACATGAAAGGAGACGTCA AATATGCAGACATCGAGTCCTCCAACTACATGGCCCCTTACGATAACTACGTTCCCTCTGCCCCTGAGAGGACCTGCCGAGCAACTTTGA TCAACGAGTCTCCAGTGCTAAGCTACATGGACCTCGTGGGCTTCAGCTACCAGGTGGCCAATGGCATGGAGTTTCTGGCCTCCAAGAACT GCGTCCACAGAGACCTGGCGGCTAGGAACGTGCTCATCTGTGAAGGCAAGCTGGTCAAGATCTGTGACTTTGGCCTGGCTCGAGACATCA TGCGGGACTCGAATTACATCTCCAAAGGCAGCACCTTTTTGCCTTTAAAGTGGATGGCTCCGGAGAGCATCTTCAACAGCCTCTACACCA CCCTGAGCGACGTGTGGTCCTTCGGGATCCTGCTCTGGGAGATCTTCACCTTGGGTGGCACCCCTTACCCAGAGCTGCCCATGAACGAGC AGTTCTACAATGCCATCAAACGGGGTTACCGCATGGCCCAGCCTGCCCATGCCTCCGACGAGATCTATGAGATCATGCAGAAGTGCTGGG AAGAGAAGTTTGAGATTCGGCCCCCCTTCTCCCAGCTGGTGCTGCTTCTCGAGAGACTGTTGGGCGAAGGTTACAAAAAGAAGTACCAGC AGGTGGATGAGGAGTTTCTGAGGAGTGACCACCCAGCCATCCTTCGGTCCCAGGCCCGCTTGCCTGGGTTCCATGGCCTCCGATCTCCCC TGGACACCAGCTCCGTCCTCTATACTGCCGTGCAGCCCAATGAGGGTGACAACGACTATATCATCCCCCTGCCTGACCCCAAACCCGAGG TTGCTGACGAGGGCCCACTGGAGGGTTCCCCCAGCCTAGCCAGCTCCACCCTGAATGAAGTCAACACCTCCTCAACCATCTCCTGTGACA GCCCCCTGGAGCCCCAGGACGAACCAGAGCCAGAGCCCCAGCTTGAGCTCCAGGTGGAGCCGGAGCCAGAGCTGGAACAGTTGCCGGATT CGGGGTGCCCTGCGCCTCGGGCGGAAGCAGAGGATAGCTTCCTGTAGGGGGCTGGCCCCTACCCTGCCCTGCCTGAAGCTCCCCCCCTGC CAGCACCCAGCATCTCCTGGCCTGGCCTGACCGGGCTTCCTGTCAGCCAGGCTGCCCTTATCAGCTGTCCCCTTCTGGAAGCTTTCTGCT CCTGACGTGTTGTGCCCCAAACCCTGGGGCTGGCTTAGGAGGCAAGAAAACTGCAGGGGCCGTGACCAGCCCTCTGCCTCCAGGGAGGCC AACTGACTCTGAGCCAGGGTTCCCCCAGGGAACTCAGTTTTCCCATATGTAAAATGGGAAAGTTAGGCTTGATGACCCAGAATCTAGGAT TCTCTCCCTGGCTGACAGGTGGGGAGACCGAATCCCTCCCTGGGAAGATTCTTGGAGTTACTGAGGTGGTAAATTAACTTTTTTCTGTTC AGCCAGCTACCCCTCAAGGAATCATAGCTCTCTCCTCGCACTTTTATCCACCCAGGAGCTAGGGAAGAGACCCTAGCCTCCCTGGCTGCT GGCTGAGCTAGGGCCTAGCCTTGAGCAGTGTTGCCTCATCCAGAAGAAAGCCAGTCTCCTCCCTATGATGCCAGTCCCTGCGTTCCCTGG CCCGAGCTGGTCTGGGGCCATTAGGCAGCCTAATTAATGCTGGAGGCTGAGCCAAGTACAGGACACCCCCAGCCTGCAGCCCTTGCCCAG GGCACTTGGAGCACACGCAGCCATAGCAAGTGCCTGTGTCCCTGTCCTTCAGGCCCATCAGTCCTGGGGCTTTTTCTTTATCACCCTCAG TCTTAATCCATCCACCAGAGTCTAGAAGGCCAGACGGGCCCCGCATCTGTGATGAGAATGTAAATGTGCCAGTGTGGAGTGGCCACGTGT GTGTGCCAGTATATGGCCCTGGCTCTGCATTGGACCTGCTATGAGGCTTTGGAGGAATCCCTCACCCTCTCTGGGCCTCAGTTTCCCCTT CAAAAAATGAATAAGTCGGACTTATTAACTCTGAGTGCCTTGCCAGCACTAACATTCTAGAGTATTCCAGGTGGTTGCACATTTGTCCAG ATGAAGCAAGGCCATATACCCTAAACTTCCATCCTGGGGGTCAGCTGGGCTCCTGGGAGATTCCAGATCACACATCACACTCTGGGGACT CAGGAACCATGCCCCTTCCCCAGGCCCCCAGCAAGTCTCAAGAACACAGCTGCACAGGCCTTGACTTAGAGTGACAGCCGGTGTCCTGGA AAGCCCCCAGCAGCTGCCCCAGGGACATGGGAAGACCACGGGACCTCTTTCACTACCCACGATGACCTCCGGGGGTATCCTGGGCAAAAG GGACAAAGAGGGCAAATGAGATCACCTCCTGCAGCCCACCACTCCAGCACCTGTGCCGAGGTCTGCGTCGAAGACAGAATGGACAGTGAG GACAGTTATGTCTTGTAAAAGACAAGAAGCTTCAGATGGGTACCCCAAGAAGGATGTGAGAGGTGGGCGCTTTGGAGGTTTGCCCCTCAC CCACCAGCTGCCCCATCCCTGAGGCAGCGCTCCATGGGGGTATGGTTTTGTCACTGCCCAGACCTAGCAGTGACATCTCATTGTCCCCAG CCCAGTGGGCATTGGAGGTGCCAGGGGAGTCAGGGTTGTAGCCAAGACGCCCCCGCACGGGGAGGGTTGGGAAGGGGGTGCAGGAAGCTC AACCCCTCTGGGCACCAACCCTGCATTGCAGGTTGGCACCTTACTTCCCTGGGATCCCCAGAGTTGGTCCAAGGAGGGAGAGTGGGTTCT CAATACGGTACCAAAGATATAATCACCTAGGTTTACAAATATTTTTAGGACTCACGTTAACTCACATTTATACAGCAGAAATGCTATTTT >7486_7486_3_ATF7IP-PDGFRB_ATF7IP_chr12_14634119_ENST00000540793_PDGFRB_chr5_149506177_ENST00000261799_length(amino acids)=1673AA_BP=1094 MDSLEEPQKKVFKARKTMRVSDRQQLEAVYKVKEELLKTDVKLLNGNHENGDLDPTSPLENMDYIKDKEEVNGIEEICFDPEGSKAEWKE TPCILSVNVKNKQDDDLNCEPLSPHNITPEPVSKLPAEPVSGDPAPGDLDAGDPASGVLASGDSTSGDPTSSEPSSSDAASGDATSGDAP SGDVSPGDATSGDATADDLSSGDPTSSDPIPGEPVPVEPISGDCAADDIASSEITSVDLASGAPASTDPASDDLASGDLSSSELASDDLA TGELASDELTSESTFDRTFEPKSVPVCEPVPEIDNIEPSSNKDDDFLEKNGADEKLEQIQSKDSLDEKNKADNNIDANEETLETDDTTIC SDRPPENEKKVEEDIITELALGEDAISSSMEIDQGEKNEDETSADLVETINENVIEDNKSENILENTDSMETDEIIPILEKLAPSEDELT CFSKTSLLPIDETNPDLEEKMESSFGSPSKQESSESLPKEAFLVLSDEEDISGEKDESEVISQNETCSPAEVESNEKDNKPEEEEQVIHE DDERPSEKNEFSRRKRSKSEDMDNVQSKRRRYMEEEYEAEFQVKITAKGDINQKLQKVIQWLLEEKLCALQCAVFDKTLAELKTRVEKIE CNKRHKTVLTELQAKIARLTKRFEAAKEDLKKRHEHPPNPPVSPGKTVNDVNSNNNMSYRNAGTVRQMLESKRNVSESAPPSFQTPVNTV SSTNLVTPPAVVSSQPKLQTPVTSGSLTATSVLPAPNTATVVATTQVPSGNPQPTISLQPLPVILHVPVAVSSQPQLLQSHPGTLVTNQP SGNVEFISVQSPPTVSGLTKNPVSLPSLPNPTKPNNVPSVPSPSIQRNPTASAAPLGTTLAVQAVPTAHSIVQATRTSLPTVGPSGLYSP STNRGPIQMKIPISAFSTSSAAEQNSNTTPRIENQTNKTIDASVSKKAADSTSQCGKATGSDSSGVIDLTMDDEESGASQDPKKLNHTPV STMSSSQPVSRPLQPIQPAPPLQPSGVPTSGPSQTTIHLLPTAPTTVNVTHRPVTQVTTRLPVPRAPANHQVVYTTLPAPPAQAPLRGTV MQAPAVRQVNPQNTLPFKVVVISAILALVVLTIISLIILIMLWQKKPRYEIRWKVIESVSSDGHEYIYVDPMQLPYDSTWELPRDQLVLG RTLGSGAFGQVVEATAHGLSHSQATMKVAVKMLKSTARSSEKQALMSELKIMSHLGPHLNVVNLLGACTKGGPIYIITEYCRYGDLVDYL HRNKHTFLQHHSDKRRPPSAELYSNALPVGLPLPSHVSLTGESDGGYMDMSKDESVDYVPMLDMKGDVKYADIESSNYMAPYDNYVPSAP ERTCRATLINESPVLSYMDLVGFSYQVANGMEFLASKNCVHRDLAARNVLICEGKLVKICDFGLARDIMRDSNYISKGSTFLPLKWMAPE SIFNSLYTTLSDVWSFGILLWEIFTLGGTPYPELPMNEQFYNAIKRGYRMAQPAHASDEIYEIMQKCWEEKFEIRPPFSQLVLLLERLLG EGYKKKYQQVDEEFLRSDHPAILRSQARLPGFHGLRSPLDTSSVLYTAVQPNEGDNDYIIPLPDPKPEVADEGPLEGSPSLASSTLNEVN -------------------------------------------------------------- >7486_7486_4_ATF7IP-PDGFRB_ATF7IP_chr12_14634119_ENST00000544627_PDGFRB_chr5_149506177_ENST00000261799_length(transcript)=7292nt_BP=3624nt GACGGGATTCACAGGCATTATGTTACAAAACTGGCTTGCTGCCTTCTGTTTTCTTTTTCTGTGTCCTGTGTAGCTGCATTGTTTGTTGCA GTATATGCATTAGCTGTTGTCTATGTTCAGTTTCCTGCAGGCTGACAAAGTGGGAGGGGCTTTGTTTGTTACATAGCTGAGTTTTCACTG TGTGAGTTCTTGAGTGCACATTGCAGCCATCTTAATTACACTTTTGTGCAACTGAGACTGTGCAGCTGTCTCAAAATGGCTGCTAACCTA GTCTTTGTAGCTGCTTAGGCAGCAAGTATGTCAGTGAGGAGACTTGTCACATGCATCAGGACCAGAGATTCAGAATGGACAGTTTAGAAG AACCTCAGAAAAAAGTCTTTAAGGCTCGAAAAACGATGAGAGTGAGTGATCGTCAGCAACTTGAAGCAGTGTACAAGGTCAAAGAAGAAC TGTTGAAAACTGATGTCAAGCTGTTAAATGGCAACCATGAAAATGGAGATTTGGACCCAACCTCACCTTTGGAAAACATGGATTACATTA AAGACAAGGAAGAGGTGAATGGCATTGAAGAGATTTGTTTTGATCCTGAAGGAAGTAAAGCAGAATGGAAGGAAACACCCTGTATCCTAA GTGTTAATGTAAAAAACAAGCAGGATGATGATTTAAATTGTGAACCTTTGTCTCCCCATAATATAACTCCAGAACCAGTCTCTAAACTGC CTGCTGAACCAGTTTCTGGTGATCCAGCCCCTGGTGATCTGGATGCCGGAGATCCAGCCTCCGGAGTACTGGCCTCTGGTGATTCCACCT CTGGTGATCCCACCTCTAGCGAGCCCTCCTCTAGTGATGCTGCCTCTGGTGATGCAACCTCTGGTGATGCCCCTTCTGGTGATGTGTCCC CTGGTGATGCCACCTCTGGTGATGCCACTGCTGATGATCTCTCCTCTGGTGATCCCACCTCTAGTGATCCCATCCCAGGTGAACCGGTCC CTGTTGAACCCATTTCTGGTGATTGTGCCGCTGATGATATAGCCTCTAGTGAAATAACTTCTGTTGATCTGGCTTCTGGAGCACCAGCTT CCACTGATCCAGCCTCTGATGATCTGGCCTCTGGTGATCTATCCTCTAGTGAACTGGCCTCTGATGATCTGGCCACTGGTGAACTGGCCT CTGATGAGCTGACTTCTGAATCAACCTTTGATCGTACCTTTGAACCAAAGTCTGTACCAGTTTGTGAACCAGTTCCTGAAATTGACAATA TAGAACCAAGTAGCAATAAAGATGATGATTTTCTTGAAAAAAATGGAGCTGATGAAAAATTAGAGCAAATTCAGAGTAAAGACTCATTGG ATGAGAAAAATAAAGCTGATAATAATATTGATGCTAATGAAGAAACTCTAGAAACAGATGATACAACTATTTGTTCAGATCGACCTCCTG AAAATGAAAAGAAGGTAGAGGAAGATATTATCACAGAGCTTGCTCTTGGAGAAGATGCTATATCTAGCAGTATGGAAATTGACCAAGGTG AAAAGAATGAAGATGAAACTTCTGCAGATCTTGTAGAAACGATTAATGAAAATGTTATTGAAGATAACAAAAGTGAGAATATCTTAGAAA ATACAGACTCTATGGAGACAGATGAAATCATTCCTATTTTGGAAAAGCTTGCACCTTCTGAGGATGAACTTACTTGCTTTTCTAAAACAT CTCTCCTTCCAATCGATGAGACAAATCCAGATTTGGAAGAGAAAATGGAAAGTTCTTTTGGTTCACCATCTAAACAAGAAAGTAGTGAGA GTTTGCCAAAAGAAGCCTTTCTGGTCCTCTCTGATGAAGAGGATATTTCGGGTGAAAAAGATGAGTCTGAAGTTATATCGCAAAATGAAA CGTGCTCTCCAGCAGAAGTAGAAAGTAATGAAAAGGACAACAAACCTGAGGAAGAAGAGCAAGTAATACATGAAGATGATGAAAGACCTT CTGAGAAAAATGAATTTTCTAGACGAAAACGTTCTAAATCAGAAGACATGGACAATGTACAGTCTAAACGTCGTCGATATATGGAAGAAG AATATGAGGCAGAATTTCAAGTAAAGATTACAGCCAAAGGAGACATTAACCAGAAACTTCAAAAGGTTATACAGTGGTTGCTGGAAGAAA AATTGTGTGCGCTGCAGTGTGCTGTATTTGATAAGACTTTGGCAGAATTGAAAACACGAGTGGAAAAGATTGAATGTAACAAGAGGCATA AAACAGTTCTCACTGAACTACAGGCCAAGATAGCCAGGTTAACCAAACGCTTTGAAGCAGCCAAAGAAGATCTTAAGAAAAGACATGAAC ATCCACCCAACCCACCAGTATCACCAGGAAAAACTGTAAATGATGTCAACAGCAATAATAACATGTCTTACAGAAATGCAGGCACAGTGA GACAGATGCTGGAGTCCAAAAGAAATGTAAGCGAGAGTGCACCACCATCCTTTCAAACTCCTGTGAATACAGTATCTTCAACCAATCTTG TCACTCCTCCAGCAGTTGTCAGTAGTCAACCTAAATTGCAGACTCCAGTGACTTCGGGTTCCCTCACAGCAACGTCAGTTCTTCCTGCAC CCAATACAGCTACTGTAGTTGCTACTACTCAGGTGCCTAGTGGAAATCCCCAGCCTACAATCTCTTTACAGCCTTTGCCAGTGATTTTGC ATGTACCTGTTGCAGTATCCTCCCAGCCTCAGCTTCTACAGAGCCATCCAGGGACTTTGGTGACTAATCAACCATCTGGCAATGTTGAAT TCATTTCTGTGCAAAGCCCACCTACAGTGAGTGGTCTTACCAAAAATCCAGTATCCTTGCCATCCTTGCCAAATCCCACTAAACCAAACA ACGTTCCTTCTGTGCCCAGTCCTAGTATTCAAAGGAACCCTACTGCCAGTGCTGCACCATTGGGAACAACACTTGCTGTGCAGGCTGTTC CAACAGCACACTCTATTGTACAAGCCACAAGGACTTCTTTACCCACAGTGGGCCCATCAGGACTCTATAGTCCATCAACTAATCGAGGTC CTATACAGATGAAAATTCCAATTTCTGCATTTAGTACTTCGTCTGCTGCAGAACAGAACAGCAATACCACCCCAAGAATTGAAAACCAGA CAAACAAAACAATAGATGCTTCTGTCAGTAAGAAAGCAGCTGATAGCACATCACAGTGTGGAAAAGCCACTGGCAGTGATTCAAGTGGTG TCATTGATCTCACAATGGATGATGAAGAGAGTGGAGCTTCACAAGACCCCAAAAAACTAAATCACACTCCTGTATCAACCATGAGTTCTT CTCAGCCTGTGTCACGACCATTGCAACCCATACAACCAGCACCGCCTCTTCAACCATCTGGGGTGCCAACAAGTGGACCATCTCAGACCA CCATACACTTACTACCTACAGCTCCAACTACCGTGAATGTAACACATCGTCCAGTAACTCAGGTGACCACAAGACTCCCTGTACCAAGAG CTCCTGCAAACCACCAGGTGGTTTATACAACTCTTCCTGCACCACCAGCTCAGGCTCCCTTGCGAGGAACTGTTATGCAGGCTCCTGCTG TTCGGCAGGTCAATCCCCAAAATACCTTGCCCTTTAAGGTGGTGGTGATCTCAGCCATCCTGGCCCTGGTGGTGCTCACCATCATCTCCC TTATCATCCTCATCATGCTTTGGCAGAAGAAGCCACGTTACGAGATCCGATGGAAGGTGATTGAGTCTGTGAGCTCTGACGGCCATGAGT ACATCTACGTGGACCCCATGCAGCTGCCCTATGACTCCACGTGGGAGCTGCCGCGGGACCAGCTTGTGCTGGGACGCACCCTCGGCTCTG GGGCCTTTGGGCAGGTGGTGGAGGCCACGGCTCATGGCCTGAGCCATTCTCAGGCCACGATGAAAGTGGCCGTCAAGATGCTTAAATCCA CAGCCCGCAGCAGTGAGAAGCAAGCCCTTATGTCGGAGCTGAAGATCATGAGTCACCTTGGGCCCCACCTGAACGTGGTCAACCTGTTGG GGGCCTGCACCAAAGGAGGACCCATCTATATCATCACTGAGTACTGCCGCTACGGAGACCTGGTGGACTACCTGCACCGCAACAAACACA CCTTCCTGCAGCACCACTCCGACAAGCGCCGCCCGCCCAGCGCGGAGCTCTACAGCAATGCTCTGCCCGTTGGGCTCCCCCTGCCCAGCC ATGTGTCCTTGACCGGGGAGAGCGACGGTGGCTACATGGACATGAGCAAGGACGAGTCGGTGGACTATGTGCCCATGCTGGACATGAAAG GAGACGTCAAATATGCAGACATCGAGTCCTCCAACTACATGGCCCCTTACGATAACTACGTTCCCTCTGCCCCTGAGAGGACCTGCCGAG CAACTTTGATCAACGAGTCTCCAGTGCTAAGCTACATGGACCTCGTGGGCTTCAGCTACCAGGTGGCCAATGGCATGGAGTTTCTGGCCT CCAAGAACTGCGTCCACAGAGACCTGGCGGCTAGGAACGTGCTCATCTGTGAAGGCAAGCTGGTCAAGATCTGTGACTTTGGCCTGGCTC GAGACATCATGCGGGACTCGAATTACATCTCCAAAGGCAGCACCTTTTTGCCTTTAAAGTGGATGGCTCCGGAGAGCATCTTCAACAGCC TCTACACCACCCTGAGCGACGTGTGGTCCTTCGGGATCCTGCTCTGGGAGATCTTCACCTTGGGTGGCACCCCTTACCCAGAGCTGCCCA TGAACGAGCAGTTCTACAATGCCATCAAACGGGGTTACCGCATGGCCCAGCCTGCCCATGCCTCCGACGAGATCTATGAGATCATGCAGA AGTGCTGGGAAGAGAAGTTTGAGATTCGGCCCCCCTTCTCCCAGCTGGTGCTGCTTCTCGAGAGACTGTTGGGCGAAGGTTACAAAAAGA AGTACCAGCAGGTGGATGAGGAGTTTCTGAGGAGTGACCACCCAGCCATCCTTCGGTCCCAGGCCCGCTTGCCTGGGTTCCATGGCCTCC GATCTCCCCTGGACACCAGCTCCGTCCTCTATACTGCCGTGCAGCCCAATGAGGGTGACAACGACTATATCATCCCCCTGCCTGACCCCA AACCCGAGGTTGCTGACGAGGGCCCACTGGAGGGTTCCCCCAGCCTAGCCAGCTCCACCCTGAATGAAGTCAACACCTCCTCAACCATCT CCTGTGACAGCCCCCTGGAGCCCCAGGACGAACCAGAGCCAGAGCCCCAGCTTGAGCTCCAGGTGGAGCCGGAGCCAGAGCTGGAACAGT TGCCGGATTCGGGGTGCCCTGCGCCTCGGGCGGAAGCAGAGGATAGCTTCCTGTAGGGGGCTGGCCCCTACCCTGCCCTGCCTGAAGCTC CCCCCCTGCCAGCACCCAGCATCTCCTGGCCTGGCCTGACCGGGCTTCCTGTCAGCCAGGCTGCCCTTATCAGCTGTCCCCTTCTGGAAG CTTTCTGCTCCTGACGTGTTGTGCCCCAAACCCTGGGGCTGGCTTAGGAGGCAAGAAAACTGCAGGGGCCGTGACCAGCCCTCTGCCTCC AGGGAGGCCAACTGACTCTGAGCCAGGGTTCCCCCAGGGAACTCAGTTTTCCCATATGTAAAATGGGAAAGTTAGGCTTGATGACCCAGA ATCTAGGATTCTCTCCCTGGCTGACAGGTGGGGAGACCGAATCCCTCCCTGGGAAGATTCTTGGAGTTACTGAGGTGGTAAATTAACTTT TTTCTGTTCAGCCAGCTACCCCTCAAGGAATCATAGCTCTCTCCTCGCACTTTTATCCACCCAGGAGCTAGGGAAGAGACCCTAGCCTCC CTGGCTGCTGGCTGAGCTAGGGCCTAGCCTTGAGCAGTGTTGCCTCATCCAGAAGAAAGCCAGTCTCCTCCCTATGATGCCAGTCCCTGC GTTCCCTGGCCCGAGCTGGTCTGGGGCCATTAGGCAGCCTAATTAATGCTGGAGGCTGAGCCAAGTACAGGACACCCCCAGCCTGCAGCC CTTGCCCAGGGCACTTGGAGCACACGCAGCCATAGCAAGTGCCTGTGTCCCTGTCCTTCAGGCCCATCAGTCCTGGGGCTTTTTCTTTAT CACCCTCAGTCTTAATCCATCCACCAGAGTCTAGAAGGCCAGACGGGCCCCGCATCTGTGATGAGAATGTAAATGTGCCAGTGTGGAGTG GCCACGTGTGTGTGCCAGTATATGGCCCTGGCTCTGCATTGGACCTGCTATGAGGCTTTGGAGGAATCCCTCACCCTCTCTGGGCCTCAG TTTCCCCTTCAAAAAATGAATAAGTCGGACTTATTAACTCTGAGTGCCTTGCCAGCACTAACATTCTAGAGTATTCCAGGTGGTTGCACA TTTGTCCAGATGAAGCAAGGCCATATACCCTAAACTTCCATCCTGGGGGTCAGCTGGGCTCCTGGGAGATTCCAGATCACACATCACACT CTGGGGACTCAGGAACCATGCCCCTTCCCCAGGCCCCCAGCAAGTCTCAAGAACACAGCTGCACAGGCCTTGACTTAGAGTGACAGCCGG TGTCCTGGAAAGCCCCCAGCAGCTGCCCCAGGGACATGGGAAGACCACGGGACCTCTTTCACTACCCACGATGACCTCCGGGGGTATCCT GGGCAAAAGGGACAAAGAGGGCAAATGAGATCACCTCCTGCAGCCCACCACTCCAGCACCTGTGCCGAGGTCTGCGTCGAAGACAGAATG GACAGTGAGGACAGTTATGTCTTGTAAAAGACAAGAAGCTTCAGATGGGTACCCCAAGAAGGATGTGAGAGGTGGGCGCTTTGGAGGTTT GCCCCTCACCCACCAGCTGCCCCATCCCTGAGGCAGCGCTCCATGGGGGTATGGTTTTGTCACTGCCCAGACCTAGCAGTGACATCTCAT TGTCCCCAGCCCAGTGGGCATTGGAGGTGCCAGGGGAGTCAGGGTTGTAGCCAAGACGCCCCCGCACGGGGAGGGTTGGGAAGGGGGTGC AGGAAGCTCAACCCCTCTGGGCACCAACCCTGCATTGCAGGTTGGCACCTTACTTCCCTGGGATCCCCAGAGTTGGTCCAAGGAGGGAGA GTGGGTTCTCAATACGGTACCAAAGATATAATCACCTAGGTTTACAAATATTTTTAGGACTCACGTTAACTCACATTTATACAGCAGAAA TGCTATTTTGTATGCTGTTGAGTTTTTCTATCTGTGTACTTTTTTTTAAGGGAAAGATTTTAATATTAAACCTGGTGCTTCTCACTCACA >7486_7486_4_ATF7IP-PDGFRB_ATF7IP_chr12_14634119_ENST00000544627_PDGFRB_chr5_149506177_ENST00000261799_length(amino acids)=1681AA_BP=1102 MHQDQRFRMDSLEEPQKKVFKARKTMRVSDRQQLEAVYKVKEELLKTDVKLLNGNHENGDLDPTSPLENMDYIKDKEEVNGIEEICFDPE GSKAEWKETPCILSVNVKNKQDDDLNCEPLSPHNITPEPVSKLPAEPVSGDPAPGDLDAGDPASGVLASGDSTSGDPTSSEPSSSDAASG DATSGDAPSGDVSPGDATSGDATADDLSSGDPTSSDPIPGEPVPVEPISGDCAADDIASSEITSVDLASGAPASTDPASDDLASGDLSSS ELASDDLATGELASDELTSESTFDRTFEPKSVPVCEPVPEIDNIEPSSNKDDDFLEKNGADEKLEQIQSKDSLDEKNKADNNIDANEETL ETDDTTICSDRPPENEKKVEEDIITELALGEDAISSSMEIDQGEKNEDETSADLVETINENVIEDNKSENILENTDSMETDEIIPILEKL APSEDELTCFSKTSLLPIDETNPDLEEKMESSFGSPSKQESSESLPKEAFLVLSDEEDISGEKDESEVISQNETCSPAEVESNEKDNKPE EEEQVIHEDDERPSEKNEFSRRKRSKSEDMDNVQSKRRRYMEEEYEAEFQVKITAKGDINQKLQKVIQWLLEEKLCALQCAVFDKTLAEL KTRVEKIECNKRHKTVLTELQAKIARLTKRFEAAKEDLKKRHEHPPNPPVSPGKTVNDVNSNNNMSYRNAGTVRQMLESKRNVSESAPPS FQTPVNTVSSTNLVTPPAVVSSQPKLQTPVTSGSLTATSVLPAPNTATVVATTQVPSGNPQPTISLQPLPVILHVPVAVSSQPQLLQSHP GTLVTNQPSGNVEFISVQSPPTVSGLTKNPVSLPSLPNPTKPNNVPSVPSPSIQRNPTASAAPLGTTLAVQAVPTAHSIVQATRTSLPTV GPSGLYSPSTNRGPIQMKIPISAFSTSSAAEQNSNTTPRIENQTNKTIDASVSKKAADSTSQCGKATGSDSSGVIDLTMDDEESGASQDP KKLNHTPVSTMSSSQPVSRPLQPIQPAPPLQPSGVPTSGPSQTTIHLLPTAPTTVNVTHRPVTQVTTRLPVPRAPANHQVVYTTLPAPPA QAPLRGTVMQAPAVRQVNPQNTLPFKVVVISAILALVVLTIISLIILIMLWQKKPRYEIRWKVIESVSSDGHEYIYVDPMQLPYDSTWEL PRDQLVLGRTLGSGAFGQVVEATAHGLSHSQATMKVAVKMLKSTARSSEKQALMSELKIMSHLGPHLNVVNLLGACTKGGPIYIITEYCR YGDLVDYLHRNKHTFLQHHSDKRRPPSAELYSNALPVGLPLPSHVSLTGESDGGYMDMSKDESVDYVPMLDMKGDVKYADIESSNYMAPY DNYVPSAPERTCRATLINESPVLSYMDLVGFSYQVANGMEFLASKNCVHRDLAARNVLICEGKLVKICDFGLARDIMRDSNYISKGSTFL PLKWMAPESIFNSLYTTLSDVWSFGILLWEIFTLGGTPYPELPMNEQFYNAIKRGYRMAQPAHASDEIYEIMQKCWEEKFEIRPPFSQLV LLLERLLGEGYKKKYQQVDEEFLRSDHPAILRSQARLPGFHGLRSPLDTSSVLYTAVQPNEGDNDYIIPLPDPKPEVADEGPLEGSPSLA -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for ATF7IP-PDGFRB |
Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
Hgene | Hgene's interactors | Tgene | Tgene's interactors |
- Retained PPIs in in-frame fusion. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
Hgene | ATF7IP | chr12:14634119 | chr5:149506177 | ENST00000261168 | + | 13 | 15 | 562_817 | 1093.3333333333333 | 1271.0 | SETDB1 |
Hgene | ATF7IP | chr12:14634119 | chr5:149506177 | ENST00000540793 | + | 12 | 14 | 562_817 | 1093.3333333333333 | 1271.0 | SETDB1 |
Hgene | ATF7IP | chr12:14634119 | chr5:149506177 | ENST00000261168 | + | 13 | 15 | 965_975 | 1093.3333333333333 | 1271.0 | SUMO |
Hgene | ATF7IP | chr12:14634119 | chr5:149506177 | ENST00000540793 | + | 12 | 14 | 965_975 | 1093.3333333333333 | 1271.0 | SUMO |
- Lost PPIs in in-frame fusion. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
Hgene | ATF7IP | chr12:14634119 | chr5:149506177 | ENST00000261168 | + | 13 | 15 | 1154_1270 | 1093.3333333333333 | 1271.0 | MBD1 |
Hgene | ATF7IP | chr12:14634119 | chr5:149506177 | ENST00000540793 | + | 12 | 14 | 1154_1270 | 1093.3333333333333 | 1271.0 | MBD1 |
Hgene | ATF7IP | chr12:14634119 | chr5:149506177 | ENST00000543189 | + | 1 | 13 | 1154_1270 | 0 | 1106.0 | MBD1 |
Hgene | ATF7IP | chr12:14634119 | chr5:149506177 | ENST00000543189 | + | 1 | 13 | 562_817 | 0 | 1106.0 | SETDB1 |
Hgene | ATF7IP | chr12:14634119 | chr5:149506177 | ENST00000543189 | + | 1 | 13 | 965_975 | 0 | 1106.0 | SUMO |
- Retained PPIs, but lost function due to frame-shift fusion. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for ATF7IP-PDGFRB |
Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Tgene | PDGFRB | P09619 | DB00619 | Imatinib | Antagonist | Small molecule | Approved |
Tgene | PDGFRB | P09619 | DB00619 | Imatinib | Antagonist | Small molecule | Approved |
Tgene | PDGFRB | P09619 | DB00619 | Imatinib | Antagonist | Small molecule | Approved |
Tgene | PDGFRB | P09619 | DB06589 | Pazopanib | Inhibitor | Small molecule | Approved |
Tgene | PDGFRB | P09619 | DB06589 | Pazopanib | Inhibitor | Small molecule | Approved |
Tgene | PDGFRB | P09619 | DB06589 | Pazopanib | Inhibitor | Small molecule | Approved |
Tgene | PDGFRB | P09619 | DB08896 | Regorafenib | Inhibitor | Small molecule | Approved |
Tgene | PDGFRB | P09619 | DB08896 | Regorafenib | Inhibitor | Small molecule | Approved |
Tgene | PDGFRB | P09619 | DB08896 | Regorafenib | Inhibitor | Small molecule | Approved |
Tgene | PDGFRB | P09619 | DB09079 | Nintedanib | Inhibitor | Small molecule | Approved |
Tgene | PDGFRB | P09619 | DB09079 | Nintedanib | Inhibitor | Small molecule | Approved |
Tgene | PDGFRB | P09619 | DB09079 | Nintedanib | Inhibitor | Small molecule | Approved |
Tgene | PDGFRB | P09619 | DB10770 | Foreskin fibroblast (neonatal) | Agonist | Biotech | Approved |
Tgene | PDGFRB | P09619 | DB10770 | Foreskin fibroblast (neonatal) | Agonist | Biotech | Approved |
Tgene | PDGFRB | P09619 | DB10770 | Foreskin fibroblast (neonatal) | Agonist | Biotech | Approved |
Tgene | PDGFRB | P09619 | DB14840 | Ripretinib | Inhibitor | Small molecule | Approved |
Tgene | PDGFRB | P09619 | DB14840 | Ripretinib | Inhibitor | Small molecule | Approved |
Tgene | PDGFRB | P09619 | DB14840 | Ripretinib | Inhibitor | Small molecule | Approved |
Tgene | PDGFRB | P09619 | DB00102 | Becaplermin | Biotech | Approved|Investigational | |
Tgene | PDGFRB | P09619 | DB00102 | Becaplermin | Biotech | Approved|Investigational | |
Tgene | PDGFRB | P09619 | DB00102 | Becaplermin | Biotech | Approved|Investigational | |
Tgene | PDGFRB | P09619 | DB00398 | Sorafenib | Antagonist | Small molecule | Approved|Investigational |
Tgene | PDGFRB | P09619 | DB00398 | Sorafenib | Antagonist | Small molecule | Approved|Investigational |
Tgene | PDGFRB | P09619 | DB00398 | Sorafenib | Antagonist | Small molecule | Approved|Investigational |
Tgene | PDGFRB | P09619 | DB01254 | Dasatinib | Antagonist | Small molecule | Approved|Investigational |
Tgene | PDGFRB | P09619 | DB01254 | Dasatinib | Antagonist | Small molecule | Approved|Investigational |
Tgene | PDGFRB | P09619 | DB01254 | Dasatinib | Antagonist | Small molecule | Approved|Investigational |
Tgene | PDGFRB | P09619 | DB01268 | Sunitinib | Inhibitor | Small molecule | Approved|Investigational |
Tgene | PDGFRB | P09619 | DB01268 | Sunitinib | Inhibitor | Small molecule | Approved|Investigational |
Tgene | PDGFRB | P09619 | DB01268 | Sunitinib | Inhibitor | Small molecule | Approved|Investigational |
Tgene | PDGFRB | P09619 | DB06595 | Midostaurin | Antagonist|Inhibitor | Small molecule | Approved|Investigational |
Tgene | PDGFRB | P09619 | DB06595 | Midostaurin | Antagonist|Inhibitor | Small molecule | Approved|Investigational |
Tgene | PDGFRB | P09619 | DB06595 | Midostaurin | Antagonist|Inhibitor | Small molecule | Approved|Investigational |
Tgene | PDGFRB | P09619 | DB12010 | Fostamatinib | Inhibitor | Small molecule | Approved|Investigational |
Tgene | PDGFRB | P09619 | DB12010 | Fostamatinib | Inhibitor | Small molecule | Approved|Investigational |
Tgene | PDGFRB | P09619 | DB12010 | Fostamatinib | Inhibitor | Small molecule | Approved|Investigational |
Tgene | PDGFRB | P09619 | DB12147 | Erdafitinib | Substrate | Small molecule | Approved|Investigational |
Tgene | PDGFRB | P09619 | DB12147 | Erdafitinib | Substrate | Small molecule | Approved|Investigational |
Tgene | PDGFRB | P09619 | DB12147 | Erdafitinib | Substrate | Small molecule | Approved|Investigational |
Tgene | PDGFRB | P09619 | DB12978 | Pexidartinib | Inhibitor | Small molecule | Approved|Investigational |
Tgene | PDGFRB | P09619 | DB12978 | Pexidartinib | Inhibitor | Small molecule | Approved|Investigational |
Tgene | PDGFRB | P09619 | DB12978 | Pexidartinib | Inhibitor | Small molecule | Approved|Investigational |
Tgene | PDGFRB | P09619 | DB15822 | Pralsetinib | Inhibitor | Small molecule | Approved|Investigational |
Tgene | PDGFRB | P09619 | DB15822 | Pralsetinib | Inhibitor | Small molecule | Approved|Investigational |
Tgene | PDGFRB | P09619 | DB15822 | Pralsetinib | Inhibitor | Small molecule | Approved|Investigational |
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Related Diseases for ATF7IP-PDGFRB |
Diseases associated with fusion partners. (DisGeNet 4.0) |
Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
Hgene | ATF7IP | C0023485 | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma | 1 | CTD_human |
Hgene | ATF7IP | C0027654 | Embryonal Neoplasm | 1 | CTD_human |
Hgene | ATF7IP | C0027658 | Neoplasms, Germ Cell and Embryonal | 1 | CTD_human |
Hgene | ATF7IP | C0039590 | Testicular Neoplasms | 1 | CTD_human |
Hgene | ATF7IP | C0153594 | Malignant neoplasm of testis | 1 | CTD_human |
Hgene | ATF7IP | C0205851 | Germ cell tumor | 1 | CTD_human |
Hgene | ATF7IP | C0205852 | Neoplasms, Embryonal and Mixed | 1 | CTD_human |
Hgene | ATF7IP | C0740345 | Germ Cell Cancer | 1 | CTD_human |
Hgene | ATF7IP | C0751364 | Cancer, Embryonal | 1 | CTD_human |
Hgene | ATF7IP | C0751365 | Cancer, Embryonal and Mixed | 1 | CTD_human |
Hgene | ATF7IP | C1720811 | Tumor of Rete Testis | 1 | CTD_human |
Tgene | C3554321 | BASAL GANGLIA CALCIFICATION, IDIOPATHIC, 4 | 6 | CTD_human;GENOMICS_ENGLAND;UNIPROT | |
Tgene | C0393590 | Fahr's syndrome (disorder) | 3 | GENOMICS_ENGLAND;ORPHANET | |
Tgene | C4225270 | Kosaki overgrowth syndrome | 3 | CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT | |
Tgene | C4551572 | MYOFIBROMATOSIS, INFANTILE, 1 | 3 | GENOMICS_ENGLAND;UNIPROT | |
Tgene | C0013421 | Dystonia | 2 | GENOMICS_ENGLAND | |
Tgene | C0023480 | Leukemia, Myelomonocytic, Chronic | 2 | ORPHANET | |
Tgene | C0023893 | Liver Cirrhosis, Experimental | 2 | CTD_human | |
Tgene | C0036341 | Schizophrenia | 2 | PSYGENET | |
Tgene | C0432284 | Infantile myofibromatosis | 2 | CTD_human;GENOMICS_ENGLAND;ORPHANET | |
Tgene | C0004782 | Basal Ganglia Diseases | 1 | CTD_human | |
Tgene | C0006663 | Calcinosis | 1 | CTD_human | |
Tgene | C0015371 | Extrapyramidal Disorders | 1 | CTD_human | |
Tgene | C0036337 | Schizoaffective Disorder | 1 | PSYGENET | |
Tgene | C0206648 | Myofibromatosis | 1 | GENOMICS_ENGLAND | |
Tgene | C0263628 | Tumoral calcinosis | 1 | CTD_human | |
Tgene | C0521174 | Microcalcification | 1 | CTD_human | |
Tgene | C0750951 | Lenticulostriate Disorders | 1 | CTD_human | |
Tgene | C1333046 | Myeloproliferative Neoplasm, Unclassifiable | 1 | ORPHANET | |
Tgene | C1866182 | Penttinen-Aula syndrome | 1 | CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT | |
Tgene | C3472621 | Myeloid neoplasm with beta-type platelet-derived growth factor receptor gene rearrangement | 1 | ORPHANET | |
Tgene | C3714756 | Intellectual Disability | 1 | GENOMICS_ENGLAND |