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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:CCAR1-PAWR (FusionGDB2 ID:HG55749TG5074) |
Fusion Gene Summary for CCAR1-PAWR |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: CCAR1-PAWR | Fusion gene ID: hg55749tg5074 | Hgene | Tgene | Gene symbol | CCAR1 | PAWR | Gene ID | 55749 | 5074 |
| Gene name | cell division cycle and apoptosis regulator 1 | pro-apoptotic WT1 regulator | |
| Synonyms | - | PAR4|Par-4 | |
| Cytomap | ('CCAR1')('PAWR') 10q21.3 | 12q21.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | cell division cycle and apoptosis regulator protein 1cell cycle and apoptosis regulatory protein 1death inducer with SAP domain | PRKC apoptosis WT1 regulator proteinPRKC, apoptosis, WT1, regulatorWT1-interacting proteinprostate apoptosis response protein 4prostate apoptosis response protein PAR-4prostate apoptosis response-4transcriptional repressor PAR4 | |
| Modification date | 20200313 | 20200313 | |
| UniProtAcc | . | . | |
| Ensembl transtripts involved in fusion gene | ENST00000265872, ENST00000535016, ENST00000543719, ENST00000483264, | ||
| Fusion gene scores | * DoF score | 13 X 11 X 8=1144 | 14 X 10 X 7=980 |
| # samples | 17 | 16 | |
| ** MAII score | log2(17/1144*10)=-2.75048040064069 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(16/980*10)=-2.61470984411521 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: CCAR1 [Title/Abstract] AND PAWR [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | CCAR1(70546400)-PAWR(79988215), # samples:1 | ||
| Anticipated loss of major functional domain due to fusion event. | CCAR1-PAWR seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. CCAR1-PAWR seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. CCAR1-PAWR seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. CCAR1-PAWR seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | CCAR1 | GO:0043065 | positive regulation of apoptotic process | 12816952 |
| Fusion gene breakpoints across CCAR1 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across PAWR (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
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Fusion Gene ORF analysis for CCAR1-PAWR |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000535016 | ENST00000328827 | CCAR1 | chr10 | 70546400 | + | PAWR | chr12 | 79988215 | - | 0.000150731 | 0.9998492 |
| ENST00000265872 | ENST00000328827 | CCAR1 | chr10 | 70546400 | + | PAWR | chr12 | 79988215 | - | 0.000131291 | 0.99986875 |
| ENST00000543719 | ENST00000328827 | CCAR1 | chr10 | 70546400 | + | PAWR | chr12 | 79988215 | - | 0.000150495 | 0.99984944 |
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Fusion Genomic Features for CCAR1-PAWR |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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Fusion Protein Features for CCAR1-PAWR |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr10:70546400/chr12:79988215) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | . |
| FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. | FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | PAWR | chr10:70546400 | chr12:79988215 | ENST00000328827 | 4 | 7 | 300_340 | 277 | 341.0 | Region | Note=Leucine-zipper |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | CCAR1 | chr10:70546400 | chr12:79988215 | ENST00000265872 | + | 1 | 25 | 1033_1114 | 0 | 1151.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | CCAR1 | chr10:70546400 | chr12:79988215 | ENST00000265872 | + | 1 | 25 | 594_618 | 0 | 1151.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | CCAR1 | chr10:70546400 | chr12:79988215 | ENST00000535016 | + | 1 | 24 | 1033_1114 | 0 | 1136.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | CCAR1 | chr10:70546400 | chr12:79988215 | ENST00000535016 | + | 1 | 24 | 594_618 | 0 | 1136.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | CCAR1 | chr10:70546400 | chr12:79988215 | ENST00000543719 | + | 1 | 24 | 1033_1114 | 0 | 1136.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | CCAR1 | chr10:70546400 | chr12:79988215 | ENST00000543719 | + | 1 | 24 | 594_618 | 0 | 1136.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | CCAR1 | chr10:70546400 | chr12:79988215 | ENST00000265872 | + | 1 | 25 | 293_361 | 0 | 1151.0 | Compositional bias | Note=Arg-rich |
| Hgene | CCAR1 | chr10:70546400 | chr12:79988215 | ENST00000265872 | + | 1 | 25 | 673_889 | 0 | 1151.0 | Compositional bias | Note=Glu-rich |
| Hgene | CCAR1 | chr10:70546400 | chr12:79988215 | ENST00000265872 | + | 1 | 25 | 73_79 | 0 | 1151.0 | Compositional bias | Note=Poly-Ala |
| Hgene | CCAR1 | chr10:70546400 | chr12:79988215 | ENST00000535016 | + | 1 | 24 | 293_361 | 0 | 1136.0 | Compositional bias | Note=Arg-rich |
| Hgene | CCAR1 | chr10:70546400 | chr12:79988215 | ENST00000535016 | + | 1 | 24 | 673_889 | 0 | 1136.0 | Compositional bias | Note=Glu-rich |
| Hgene | CCAR1 | chr10:70546400 | chr12:79988215 | ENST00000535016 | + | 1 | 24 | 73_79 | 0 | 1136.0 | Compositional bias | Note=Poly-Ala |
| Hgene | CCAR1 | chr10:70546400 | chr12:79988215 | ENST00000543719 | + | 1 | 24 | 293_361 | 0 | 1136.0 | Compositional bias | Note=Arg-rich |
| Hgene | CCAR1 | chr10:70546400 | chr12:79988215 | ENST00000543719 | + | 1 | 24 | 673_889 | 0 | 1136.0 | Compositional bias | Note=Glu-rich |
| Hgene | CCAR1 | chr10:70546400 | chr12:79988215 | ENST00000543719 | + | 1 | 24 | 73_79 | 0 | 1136.0 | Compositional bias | Note=Poly-Ala |
| Hgene | CCAR1 | chr10:70546400 | chr12:79988215 | ENST00000265872 | + | 1 | 25 | 636_670 | 0 | 1151.0 | Domain | SAP |
| Hgene | CCAR1 | chr10:70546400 | chr12:79988215 | ENST00000535016 | + | 1 | 24 | 636_670 | 0 | 1136.0 | Domain | SAP |
| Hgene | CCAR1 | chr10:70546400 | chr12:79988215 | ENST00000543719 | + | 1 | 24 | 636_670 | 0 | 1136.0 | Domain | SAP |
| Tgene | PAWR | chr10:70546400 | chr12:79988215 | ENST00000328827 | 4 | 7 | 186_206 | 277 | 341.0 | Coiled coil | Ontology_term=ECO:0000255 | |
| Tgene | PAWR | chr10:70546400 | chr12:79988215 | ENST00000328827 | 4 | 7 | 49_120 | 277 | 341.0 | Compositional bias | Note=Ala-rich | |
| Tgene | PAWR | chr10:70546400 | chr12:79988215 | ENST00000328827 | 4 | 7 | 145_161 | 277 | 341.0 | Motif | Nuclear localization signal | |
| Tgene | PAWR | chr10:70546400 | chr12:79988215 | ENST00000328827 | 4 | 7 | 68_72 | 277 | 341.0 | Motif | B30.2/SPRY domain-binding motif | |
| Tgene | PAWR | chr10:70546400 | chr12:79988215 | ENST00000328827 | 4 | 7 | 145_203 | 277 | 341.0 | Region | Note=Selective for apoptosis induction in cancer cells (SAC) |
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Fusion Gene Sequence for CCAR1-PAWR |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >13523_13523_1_CCAR1-PAWR_CCAR1_chr10_70546400_ENST00000265872_PAWR_chr12_79988215_ENST00000328827_length(transcript)=10826nt_BP=2901nt GAAGTTGGCGCATGCGCCTAAAGCTGACGGGTTTGAAATGGCTTCGATGTTAGCCGGGACCCGACTCAGATCGATGCTATAGAAGACAAA CAAGGGAAGGTTTTTTTTCCTTTTGCATCATGGCTCAATTTGGAGGACAGAAGAATCCGCCATGGGCTACTCAGTTTACAGCCACTGCAG TATCACAGCCAGCTGCACTGGGTGTTCAACAGCCATCACTCCTTGGAGCATCTCCTACCATTTATACACAGCAAACTGCATTGGCAGCAG CAGGCCTTACCACACAAACTCCAGCAAACTATCAGTTAACACAAACTGCTGCATTGCAGCAACAAGCCGCAGCTGCAGCAGCTGCATTAC AACAGCAATATTCACAACCTCAGCAGGCCCTGTATAGTGTGCAACAACAGTTACAGCAACCCCAGCAAACCCTCTTAACACAGCCAGCTG TTGCACTGCCTACAAGCCTTAGCCTGTCTACTCCTCAGCCAACAGCACAAATAACTGTATCATATCCAACACCAAGGTCCAGTCAACAGC AAACCCAGCCTCAGAAGCAGCGTGTTTTCACAGGGGTGGTTACAAAACTACATGATACGTTTGGATTTGTGGATGAAGATGTATTCTTTC AGCTTAGTGCTGTCAAAGGGAAAACCCCCCAAGTAGGTGACAGAGTATTGGTTGAAGCTACTTATAATCCTAATATGCCTTTTAAATGGA ATGCACAGAGAATTCAAACACTACCAAATCAGAATCAGTCGCAAACCCAGCCATTACTGAAGACTCCTCCTGCTGTACTTCAGCCAATTG CACCACAGACAACATTTGGTGTTCAGACTCAGCCCCAGCCCCAGTCACTGCTGCAGGCACAGATTTCAGCAGCTTCTATTACACCACTAT TGCAGACTCAACCACAGCCCTTATTACAGCAGCCTCAGCAAAAAGCTGGTTTATTGCAGCCTCCTGTTCGTATAGTTTCACAGCCACAAC CGGCACGACGATTAGATCCCCCATCCCGATTTTCAGGAAGAAATGACAGAGGGGATCAAGTGCCTAACAGAAAAGATGATCGAAGTCGTG AGAGAGAGAGAGAAAGACGTAGATCGAGAGAAAGATCACCTCAGAGGAAACGTTCCCGGGAAAGATCTCCACGAAGAGAGCGAGAGCGAT CACCTCGGAGAGTTCGACGTGTTGTTCCACGTTACACAGTTCAGTTTTCAAAGTTTTCTTTAGATTGTCCCAGTTGTGACATGATGGAAC TAAGGCGCCGTTATCAAAATTTGTATATACCTAGTGACTTTTTTGATGCTCAATTTACATGGGTGGATGCTTTCCCTTTGTCAAGACCAT TTCAGCTGGGAAATTACTGCAATTTTTATGTAATGCACAGAGAAGTAGAGTCCTTAGAAAAAAATATGGCCATTCTTGATCCACCAGATG CTGACCACTTATACAGTGCAAAGGTAATGCTGATGGCTAGCCCTAGTATGGAAGATTTATATCATAAGTCATGTGCTCTTGCTGAGGACC CACAAGAACTTCGAGATGGATTCCAACATCCTGCTAGACTTGTTAAGTTTTTAGTGGGCATGAAAGGCAAGGATGAAGCTATGGCCATTG GAGGCCACTGGTCTCCTTCGTTGGATGGACCAGACCCAGAAAAAGATCCCTCTGTGTTGATTAAGACTGCTATTCGTTGTTGTAAGGCTC TGACAGGCATTGATCTAAGTGTGTGCACACAATGGTACCGTTTTGCAGAGATTCGCTACCATCGCCCTGAGGAGACCCACAAGGGGCGTA CAGTTCCAGCTCATGTGGAGACAGTGGTTTTATTTTTCCCGGATGTTTGGCATTGCCTTCCCACCCGCTCAGAGTGGGAAACCCTCTCCC GAGGATACAAGCAGCAGCTGGTCGAGAAGCTTCAGGGTGAACGCAAGGAGGCTGATGGAGAACAGGATGAAGAAGAGAAGGATGATGGTG AAGCTAAAGAAATTTCTACACCTACCCATTGGTCTAAACTTGATCCAAAGACAATGAAGGTAAATGACCTCCGAAAAGAATTAGAAAGTC GAGCTCTTAGTTCCAAAGGATTAAAATCCCAGTTAATAGCCCGATTGACAAAACAGCTTAAAGTAGAGGAACAAAAAGAAGAACAGAAGG AGTTAGAGAAATCTGAAAAAGAAGAGGATGAGGATGATGATAGGAAATCTGAAGACGATAAAGAGGAAGAAGAAAGGAAACGTCAAGAGG AAATAGAACGCCAGCGTCGAGAAAGAAGATATATTTTGCCTGATGAACCGGCCATCATTGTACATCCAAATTGGGCTGCAAAAAGTGGCA AGTTTGATTGTAGCATCATGTCTTTGAGTGTCCTATTGGACTACAGATTAGAGGATAATAAAGAACATTCATTTGAGGTTTCATTGTTTG CGGAACTTTTCAACGAAATGCTTCAAAGAGATTTTGGTGTCCGTATATACAAATCATTACTGTCTCTTCCTGAGAAAGAGGACAAAAAAG AAAAGGATAAAAAAAGCAAAAAAGATGAGAGAAAAGATAAAAAAGAAGAAAGAGATGATGAAACTGATGAACCAAAACCCAAACGGAGAA AATCAGGCGATGATAAAGATAAAAAAGAAGATAGAGATGAAAGGAAGAAAGAAGATAAAAGAAAAGATGATTCTAAAGATGATGATGAAA CTGAAGAAGATAACAATCAAGATGAATATGACCCTATGGAAGCAGAAGAAGCTGAGGATGAAGAAGATGATAGGGATGAGGAAGAAATGA CCAAACGAGATGACAAAAGAGATATCAACAGATACTGCAAGGAGAGGCCCTCTAAAGATAAGTTTGGAAGAAATACTTTATACTCTTGGA CTACATCTTTCTCGGGCTCAGGAAGTAGTAAGAGAAAGACAAGAAAACCTAAGACTTGTGAGACTGATGCAAGATAAAGAGGAAATGATT GGAAAACTCAAAGAAGAAATTGATTTATTAAATAGAGACCTAGATGACATAGAAGATGAAAATGAACAGCTAAAGCAGGAAAATAAAACT CTTTTGAAAGTTGTGGGTCAGCTGACCAGGTAGAGGATTCAAGACTCAATGTGGAAAAAATATTTTAAACTACTGATTGAATGTTAATGG TCAATGCTAGCACAATATTCCTATGCTGCAATACATTAAAATAACTAAGCAAGTATATTTATTTCTAGCAAACAGATGTTTGTTTTCAAA ATACTTCTTTTTCATTATTGGTTTTAAAAAAGCATTATCCTTTTATCTCACAAATAAGTAATATCTTTCAGTTATTAAATGATAGATAAT GCCTTTTTGGTTTTGTGTGGTATTCAACTAATACATGGTTTAAAGTCACAGCCGTTTGAATATATTTTATCTTGGTAGTACATTTTCTCC CTTAGGAATATACATAGTCTTTGTTTACATGAGTTCAAATACTTTTGGGATGTTACCTTCACATGTCCTATTACTGATGTGTGCAACCTT TTATGTGTTGATGACTCACTCATAAAGGTTTTTGTCTACTGTCATTTGTTCTTTCCACTTATTCTAAGCATTTAGAGTAATAGAGTCATA CTTTTTTATAACAGCAACCTTTTAAAAGGAAAGCTCTTATAAAGTCACTGTCATGTTTTAGTTGACTAAATATAAATTTAAGAGAATACT TGAATTGTGCTATAGTAAATAAAAATTTACTATTTTGTGTTTGAATATTGAAAAATTGAATCACTTTAACTCCTGAAAAACATACAATTG TAATTTCAATGTAAAATTTCTTATGTAGGTACTACCTTTTTTTATCGTTCCAAGGTTTGCTAGTGAACACAGGATATTTTAAAAGTTTTT TATTCTTCGGGCCTGGAAAGTGTACAAAGTCAGTGTAGGAGAAAAAAATCCATATTTTTATATTAGCATGCACACTAAAAACCAAAATAT TATTCATACTTAAAACATTCATACAAAACAATATGTAAGCAGAAATAGTACTAAAATACTTTGCCTAATTTCTAAGTTGAAGAATAACAC TGGGACACAGTTTTTTCATATGAGAGAATATTCCGCTATTTCAAATTTAAGGGATTTTCTTCCTAACATTGAAATTTTAAAAACAGAGTT ACTTCTAAATAATTATACAGATTTTTTCTTCTATTAAATATTATTATTTAGAATTGTTTTTGTATTACATATTCATGTTAAGAACCCCGT CTTCCCTTAAAATACATTAAAATTATGACATTTTTGCTTTGTGATTGAATTTCAAATAGCAGTATGGTATCCTTTTATCTAGTTAATATA TGAAAGTGGCTTGAATATAGTCAAATCCATTTTAGGTACTCTACTGACTTTTTCCTTCACTTGCCAAGCCCTTTTATTGTTCACTGTTAG AAAAATAGAGAAGGTGAGACAGCTGGGGGAAAATGTGGAGTAAATGATAATCAAATGTTGAATTCTAAAAGTCTCTACATTTACCTAGGT TGGCTTTCTCCCCCAGTTCAGAAGTTTCCAGCTTGGCCAATCATCAGAATCACTTGAGGAACTTAGAAAGAACTCCCTGGCTGTAGCTCC TATGTAGGTTTAGGTTGAGACTCTGGATTCCACAATTTTTAAAGGTTACCATCTGAGGTTTCTGATCATAGTCTACTTTTGAAGCAGCTG CTGCTGTTTCTTTATTCCATTGAACACCCTGGAATTGACATAATTTTATCTATCAGCATTTCTCCCCTTTTAGTTTATTTAATAATTAAC CCGGTCTCCAGGGCAGTTTTCATATGACCATGTGTATATTCACTGCTCACGAAAAAGTTTAATGTTAGATTACCAAATTTAATATAGTTA CAGAATTACTGCATAAGGGCTTCCCTTCTTGGAGACTCTTACCCAGCATGGGAACAGTGATCTGCCCACATGACAGGGTGGTATGCCAGG CATAGTTAACTGCTTTTGGTTGTGAGGTACTCATCTTCCTTTAGTTACCCTTAGTTATGTGGCACACATGTCCTTATTGCCTAGTTCGTC ATCCACACTTTGGATCTTGTGAAAATGCTGTTAGTATCCAACCTTAAAATATATTAGTATATGGGTTTTTATTAAAAGAATTACTTTGAA TTTTCTATTTAATTCATATGTAAATAAAGGAACATTTCATTTCACTTAAAAAAATTATATCAGTTATTAGGCTGGGTGCAGTGGCTCATG CCTGTAATCCCAGCACTTTGGGAGGCCAAGGCGGGTGGATTACCAGAGTTCGGGAGTTTGAGACCAGCTTGACCAACATGGAGAAACCCC GTCTCTACTAAAAATACAAAATTAGCCAGGTGTGGTGGCGCATGCCTGTAATCCTGGCTACTCAGGAGGCTGAGGCAGGAGAATCGCTTG AAAACCCAGGAGACAGAGGTTGCGGTGAGCTGAGATTGCGCCATTGTACTCCAGCCTGGGCAAGAAGAGCGAAACTCTGTCTCCAAAAAA AAAAAAAAAAAAATTATTAATACTTTTAAAGACTGAGCTGTTTAAGAATTTTTTGGGGAACATTTCTAGCAGTGATTTTTTTGGCCTTTA ATGATAGCGTAAAGACAGGAGCCTTACAACTTAGGCAAAGCATTTCACATGCAGTCCTTCTTCCATCTCAAAATATGTACTTATTTTACA TACAGAATTTTACACTAACCATTGAAAAATAAAGTAGGATCTGCTACAGTTTCACCTGAAAATTTATAAAAAGTGTTGAGATTGGTAGAA GGTAGTTTTTAAGTACATGTGCACTACCCTAAAAGACTTGTCTATTGTCAATAAAGTGTTAGTATTTGTGAAATTATTATTCCTGTTCAG AAATACTATTTCTTAAATCTCCTGGGAATTTGTGGCATAATAAAGCACATTCAAAGTTCTAATGTATTTATGAGCTCATTTTCAAAATAG TAAGTTTGTCATCTTTAAAATGAACATGACTTGCCTCCTTGATTTCTGAAATGAATTAATTGAAGATTGCTATAGTAATCTTTATTTCAT CTTTCTAGAGTTGTTGACAATTTTATTATACAACAGTTACCATTAGAGAAGGAGGGAAGGGCTTTTGGGTGTGTATTTATAGGTACTAAG GGATTTACTAAATATAGTAGATTAGCACTGTCACACTTGTTCAAGTAGTTTCAAACATAGAAAATTAAGTATCAGGTATGTGGAGCAATG TAGTTTTTTTTTTTCTTCAGTTTAAAAAATTTTTAATTGTGGTAGAAGCAATGTATTCTTAAGGTGAAAAACCTACCTCGGTTACATGTG GTTTGTGTTTTTTGGATTAATCTGGATTTTATAATTAGAAATAAAAATGTAAGATTTTGAATCCACTTAATTTCTTGAAAATAGTACAAG TCAGTGTAATAGAGAAGCATTCATATATTCAACACTGTAAGACAAAACAGCAGAGACCTTGGATTTGATAATTGATCTGATATCCTGGAC AGTATTCATATGTACAGTGATAGGTATCTTTCTTTGGAGTTTTTTTTTTGTGCATATGTGTATAGTTTTATGGGTTCTGAGTTGGTGACC AGTAAGTTGCATGTAGTGCTGGCACTTACTTAATAACTATTCATGATATTGTTAATAACTTGTTATAGGATTGTATTCCCAATTACAGTC TCTAAGATTGTAATTGATATTATCTGAGAGGTAGTGTGACAACTTTCTTTTGTTGTTACATTAAGCCGAAAACATAATACTAATAGACAA CTAACAGTTTGCTTATCAGGCACATCAACTAAGGCACCTCCCCCCATGCTAAGTTTCTCCTGGATATATGGAAGTTGATTGTTTCCCAGT TTAAAAACTTGAACTAATATCTCCTAAGAAAATCTGAGTCCATATTGTTTTTATTTTACTTAGCTAGAATCTCATAGCATGTTAAAGTCA TATCCTTATCCCCACTAAAAATAACTATGTCTATGTGAGAGGAATATAGTATGTGGGAGCTGTATTAAATACTATTACAGGTGTTACAGA ATCTTTAAATAAATGGACATGGACCAACTTTCCATCTAGTAGTGTACGATCTATATAGTGCATGTCAGTAGCACAAAATGCAGTCTTAGC ATTAGCCTGTCTAATCTGAATAGTTTACTCAAAAGTACTTCTTTGTGTTAAGTATTCAGCCACTGTTTTTAGATCTAGTTAATAGGTTCT ATTTAATTTGCTACAACATTTACTGAATGGTGGAGTGAAAAAACTGATGCATACTGGGAAATATCTACCATTTTTTAAAGATAATGTTAA TTAGGAAAAGAACACTTTTAAGGAATTTATAGCAGTGATGAAATGAATTCAGTTATATCAGATACACCAAACTGTTGATGGTATTTAAAT GTGACTTCAAGTTAGTATTTCTGTATATATTATTGATTACTGGTTTGTTTTTAGATATGTAAGTCTGTTCTAATCTACAGTTCACATATC GACAGTTACTCTGGTAATAATAGAATGTTAGTGATGATCACTTGGTGGATGTTGATTAAGTGCCTGTGTTTTGTTTCCTCCTCTGGATAC CAAATAGGTGTATGCTACTTTTTTGGTGAACTTATTTCTTGGAAGATTTGGCTATGCTATTCAGGGTTTTTATTCTTATGTTTTTCTTCT AAATTTAAGTAGCATCCTGCTGCTACCATATTAAAGCTAAAATTTAACTTTTGCTGAAGAATCAGCTAATTCAGGTAATCCAAATATTTG TGGAAAAACATCTGGATAATTTATTGAACACATTAGTATTGTGTTAGACAGCTTTGATCATTCCCATTTCATAGGTTTTTATTGTGGAAT AGTCAACTTAATATAGATTCACTTTCAATTTGCATGTATAAAGTAATACTCAATAAAATTTTTTTCATTTATTTTTCAACAGTGGTTATT TTTTTTCTTCCTGTACTATCAGTAAAATCCTGACTATGAGTTTTACTTTTGAAGCTAAAGGATAATGCTGGTAATCTAATTATGTACCTC TTACAGAAACCATATGCAGCACTTTAAAAATCTTTATTTGGTATATTATTTTAGGTGGACAATGATTTAAGACTCAAAGCCATCATATTA AGGTCTAAATACATTAGTGGTGGGGTTTCTCGAATAAATGAGGAAGTGCACAAAAGTTCAGCCTGACTGAAAATTTTAATTGTGTTTTAA AACTACATGAATAATTTCTTGATTCAAAATCAGAACTCTTATAAACTAAATCTGATGGTGTCCAAAGAATTTCAGGTCCTTCAAAGTTTG TAAAAGATAAGTAGGGGCCTAGGAATATAAAAATTTAGACTTTTTTAGTAAATGGTTTACATAACCTTTTGTCTTAATTTGTCATTCTTC ATACACAGGCACAAGCTAATCAGTCTTCTCTACTTCTAGAACTCTAAATCTTCTCAGTAATGTCATACAAGTCTAACAAGAGGAAAAGCA TCCTTAAGTCAGTCTATTTAGATAAACTCTTCAAGTCCCTATATAAGGACGTATTCCACTAGCAAGCCAGTAAATTTTTCCAAGGTCACA TAATCTTACATGAAATGGAACCTTTCATCTTAGACTTCATCAAACTCAATTTTTTCCCTTCTAGATTCACTTTGTGTTTATGCATGCATG CACGCGTGCACACAATTCTATCAGCAGCTGTAAACTACCCACATATTTTCTTAATCTCATTTTTTCAGTTTTTCTTCATCTTTAAAAGAG GTTACATTTCATTCCTGGTCAACTCTTAAAAAGAATTATGTAATGTTGGGCCTTCATATTAAAGAGAGAGACTGGTTATAAGATCCTTTA CAGTCCATTCATTTTATTCTGATGTCTAACCAGATAGACACTAGCAAGCAAAACTTCCCTCTTAATCCTGGACCAAATGCATAATTTTAC TGTCACTTTCAAAAATCTGTTATGACTGAATCAAAATCCTTTTAAAGAAAGGAAAAAGCTCCTTTTGTGTCAAATAGTTGAACAACATGA AAACAGTATGAGCCGGTTAAAGATAGATTGAATTTTTACTTTACACATATGAAAAACAGTAAGTTTTGACTGCTGTGTATGTTATTCATG TTAATATGTGCTCAGTTATTCACTATTGTTAATCCACATATAATCAGTTGCTATCCCTGGTTAGACACACTATGGAACTTGAAATGCACA ATATTTACATTGTTAGAGGCTTCTATCCAAATATCTGCATTCCTTTAAAATGTGAACTATTTGCTGTGATTAACCAAAGGTAGATTATGT CATCAGTGGACATTTTAGCTTTATGGAAACAAATTATTAAGAAATGAATAGAAAGGTGTCTTTTTCTTTGTGTAGTGCAAAAGCCTAAAG CTATCAGTCAAAGGCCTAAGAAATCCACATTTGAAAAACGTAAATCATGATTGGTAAGAATACATTCATCTGATAGTATTGAGAAAAGTT GAAAAACTGTTAGCCTTCCATAACACATTAAACATTTTATGTATGGATGGCTGAAAGTATTGAGAAAAGCTGAAAAACTGTTAGCCTTCC ATAACACATTAAACGTTTTGTGTATGGATGGCTTAGGACAATAAACAACATCATTAAAGTAAAATTATGTCAGTCTGTTCATATTAACTT ATTTAAATCAATGAAAATTTTGATGAGATGACTAAATGGATGCTTTGGAAATGCAGGATTATAGGAGGCCTAAAAGTGCATCTTGTTTCT TGTAACCCTTTTAAAACCAATATGCCTGGCTAGGTGCAGTGGCTCATGCCTGTAATACCAACGGGGTAACACAGGGTTATGCCGTCTATA CAAAAAAATAAATGAGCTGGGCAAGATGGCATGCACCTGTAGTCCCAGCTGCTTGGTAGGCTGAGGGGGAAGGATTGCTTGAGCCTGGGA GGTCGAGACTGCAGTGAGCCAAGATCACACCACTGCACTCCAGCCTGGGTGACAGAGCAAGACTCTACCTCAAAAATAAAAATAATCAAT ATAGTTTCAATGAAGCAAAGCATCTCAGGTAACAATTTGAGCATAACTTTAACCATAACTTATGATAGCATAATAACATTCATTAGTAAT TCAGTAGCCGTATGTGCCAGGCTGTGTTAGGTGCTTTATATATTGTTTAATTTTTAAAAACTTGTGGAGTGTACAGATTGGTAAGGTGAC ATTGTATCACAAAGCTAGTCTTTGAGTCCAAAGTTTTGTGGTTTTATGTTATGATATACTTTTATCATGGAATTGTCTTATTAAATGTTT TGCCAGTGGTTCTTAAAGTGTGTTTCTGACACCAGTAGCATTGACTTCACTTAGAAACCTGTTAGAAATACAAATTATTTGGCCCCACCC AACACTTGAGTCACAAACTTTGCAGATGGGGCTCAATCTGTTTTAACAAGCGCTTCATGTAATTTTGATGCAGGCCTAAGTTTTTGAGCC ACTGCAGTATGCATTTCTATTTTTAAGCAAAGATCTTGGTCTTTCTTTTTGGACATTGTAGAAATAACATGAACTTGTTTTTTGTTTGTT TTTGTTTTGTTTTGTTTTAAGCTCCTGATCTTTGTTGGTTATGTTGCAAAAGATTGTATCAGGAGAAGCCTCAGCATGGACATTGGCATC CTGACATAACCCCCATTAATTTAGTATTCTTTCTGAAACTCAAATGGATTCTCAAGTCCAAGAGACTATGGAATAAAATCATTGTTTGTC TGTGTTAAGTTTTATCTCTGTTATTGCCTGAAGACTTTTGGTAACAATAATGCGCTTTCATCAAACTTTTAAGACTTGATTGGAAAAAAT >13523_13523_1_CCAR1-PAWR_CCAR1_chr10_70546400_ENST00000265872_PAWR_chr12_79988215_ENST00000328827_length(amino acids)=945AA_BP=927 MAQFGGQKNPPWATQFTATAVSQPAALGVQQPSLLGASPTIYTQQTALAAAGLTTQTPANYQLTQTAALQQQAAAAAAALQQQYSQPQQA LYSVQQQLQQPQQTLLTQPAVALPTSLSLSTPQPTAQITVSYPTPRSSQQQTQPQKQRVFTGVVTKLHDTFGFVDEDVFFQLSAVKGKTP QVGDRVLVEATYNPNMPFKWNAQRIQTLPNQNQSQTQPLLKTPPAVLQPIAPQTTFGVQTQPQPQSLLQAQISAASITPLLQTQPQPLLQ QPQQKAGLLQPPVRIVSQPQPARRLDPPSRFSGRNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVRRVVP RYTVQFSKFSLDCPSCDMMELRRRYQNLYIPSDFFDAQFTWVDAFPLSRPFQLGNYCNFYVMHREVESLEKNMAILDPPDADHLYSAKVM LMASPSMEDLYHKSCALAEDPQELRDGFQHPARLVKFLVGMKGKDEAMAIGGHWSPSLDGPDPEKDPSVLIKTAIRCCKALTGIDLSVCT QWYRFAEIRYHRPEETHKGRTVPAHVETVVLFFPDVWHCLPTRSEWETLSRGYKQQLVEKLQGERKEADGEQDEEEKDDGEAKEISTPTH WSKLDPKTMKVNDLRKELESRALSSKGLKSQLIARLTKQLKVEEQKEEQKELEKSEKEEDEDDDRKSEDDKEEEERKRQEEIERQRRERR YILPDEPAIIVHPNWAAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVSLFAELFNEMLQRDFGVRIYKSLLSLPEKEDKKEKDKKSKKDE RKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRKDDSKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDKRDIN -------------------------------------------------------------- >13523_13523_2_CCAR1-PAWR_CCAR1_chr10_70546400_ENST00000535016_PAWR_chr12_79988215_ENST00000328827_length(transcript)=10781nt_BP=2856nt GAAGTTGGCGCATGCGCCTAAAGCTGACGGGTTTGAAATGGCTTCGATGTTAGCCGGGACCCGACTCAGATCGATGCTATAGAAGACAAA CAAGGGAAGGTTTTTTTTCCTTTTGCATCATGGCTCAATTTGGAGGACAGAAGAATCCGCCATGGGCTACTCAGTTTACAGCCACTGCAG TATCACAGCCAGCTGCACTGGGTGTTCAACAGCCATCACTCCTTGGAGCATCTCCTACCATTTATACACAGCAAACTGCATTGGCAGCAG CAGGCCTTACCACACAAACTCCAGCAAACTATCAGTTAACACAAACTGCTGCATTGCAGCAACAAGCCGCAGCTGCAGCAGCTGCATTAC AACAGTTACAGCAACCCCAGCAAACCCTCTTAACACAGCCAGCTGTTGCACTGCCTACAAGCCTTAGCCTGTCTACTCCTCAGCCAACAG CACAAATAACTGTATCATATCCAACACCAAGGTCCAGTCAACAGCAAACCCAGCCTCAGAAGCAGCGTGTTTTCACAGGGGTGGTTACAA AACTACATGATACGTTTGGATTTGTGGATGAAGATGTATTCTTTCAGCTTAGTGCTGTCAAAGGGAAAACCCCCCAAGTAGGTGACAGAG TATTGGTTGAAGCTACTTATAATCCTAATATGCCTTTTAAATGGAATGCACAGAGAATTCAAACACTACCAAATCAGAATCAGTCGCAAA CCCAGCCATTACTGAAGACTCCTCCTGCTGTACTTCAGCCAATTGCACCACAGACAACATTTGGTGTTCAGACTCAGCCCCAGCCCCAGT CACTGCTGCAGGCACAGATTTCAGCAGCTTCTATTACACCACTATTGCAGACTCAACCACAGCCCTTATTACAGCAGCCTCAGCAAAAAG CTGGTTTATTGCAGCCTCCTGTTCGTATAGTTTCACAGCCACAACCGGCACGACGATTAGATCCCCCATCCCGATTTTCAGGAAGAAATG ACAGAGGGGATCAAGTGCCTAACAGAAAAGATGATCGAAGTCGTGAGAGAGAGAGAGAAAGACGTAGATCGAGAGAAAGATCACCTCAGA GGAAACGTTCCCGGGAAAGATCTCCACGAAGAGAGCGAGAGCGATCACCTCGGAGAGTTCGACGTGTTGTTCCACGTTACACAGTTCAGT TTTCAAAGTTTTCTTTAGATTGTCCCAGTTGTGACATGATGGAACTAAGGCGCCGTTATCAAAATTTGTATATACCTAGTGACTTTTTTG ATGCTCAATTTACATGGGTGGATGCTTTCCCTTTGTCAAGACCATTTCAGCTGGGAAATTACTGCAATTTTTATGTAATGCACAGAGAAG TAGAGTCCTTAGAAAAAAATATGGCCATTCTTGATCCACCAGATGCTGACCACTTATACAGTGCAAAGGTAATGCTGATGGCTAGCCCTA GTATGGAAGATTTATATCATAAGTCATGTGCTCTTGCTGAGGACCCACAAGAACTTCGAGATGGATTCCAACATCCTGCTAGACTTGTTA AGTTTTTAGTGGGCATGAAAGGCAAGGATGAAGCTATGGCCATTGGAGGCCACTGGTCTCCTTCGTTGGATGGACCAGACCCAGAAAAAG ATCCCTCTGTGTTGATTAAGACTGCTATTCGTTGTTGTAAGGCTCTGACAGGCATTGATCTAAGTGTGTGCACACAATGGTACCGTTTTG CAGAGATTCGCTACCATCGCCCTGAGGAGACCCACAAGGGGCGTACAGTTCCAGCTCATGTGGAGACAGTGGTTTTATTTTTCCCGGATG TTTGGCATTGCCTTCCCACCCGCTCAGAGTGGGAAACCCTCTCCCGAGGATACAAGCAGCAGCTGGTCGAGAAGCTTCAGGGTGAACGCA AGGAGGCTGATGGAGAACAGGATGAAGAAGAGAAGGATGATGGTGAAGCTAAAGAAATTTCTACACCTACCCATTGGTCTAAACTTGATC CAAAGACAATGAAGGTAAATGACCTCCGAAAAGAATTAGAAAGTCGAGCTCTTAGTTCCAAAGGATTAAAATCCCAGTTAATAGCCCGAT TGACAAAACAGCTTAAAGTAGAGGAACAAAAAGAAGAACAGAAGGAGTTAGAGAAATCTGAAAAAGAAGAGGATGAGGATGATGATAGGA AATCTGAAGACGATAAAGAGGAAGAAGAAAGGAAACGTCAAGAGGAAATAGAACGCCAGCGTCGAGAAAGAAGATATATTTTGCCTGATG AACCGGCCATCATTGTACATCCAAATTGGGCTGCAAAAAGTGGCAAGTTTGATTGTAGCATCATGTCTTTGAGTGTCCTATTGGACTACA GATTAGAGGATAATAAAGAACATTCATTTGAGGTTTCATTGTTTGCGGAACTTTTCAACGAAATGCTTCAAAGAGATTTTGGTGTCCGTA TATACAAATCATTACTGTCTCTTCCTGAGAAAGAGGACAAAAAAGAAAAGGATAAAAAAAGCAAAAAAGATGAGAGAAAAGATAAAAAAG AAGAAAGAGATGATGAAACTGATGAACCAAAACCCAAACGGAGAAAATCAGGCGATGATAAAGATAAAAAAGAAGATAGAGATGAAAGGA AGAAAGAAGATAAAAGAAAAGATGATTCTAAAGATGATGATGAAACTGAAGAAGATAACAATCAAGATGAATATGACCCTATGGAAGCAG AAGAAGCTGAGGATGAAGAAGATGATAGGGATGAGGAAGAAATGACCAAACGAGATGACAAAAGAGATATCAACAGATACTGCAAGGAGA GGCCCTCTAAAGATAAGTTTGGAAGAAATACTTTATACTCTTGGACTACATCTTTCTCGGGCTCAGGAAGTAGTAAGAGAAAGACAAGAA AACCTAAGACTTGTGAGACTGATGCAAGATAAAGAGGAAATGATTGGAAAACTCAAAGAAGAAATTGATTTATTAAATAGAGACCTAGAT GACATAGAAGATGAAAATGAACAGCTAAAGCAGGAAAATAAAACTCTTTTGAAAGTTGTGGGTCAGCTGACCAGGTAGAGGATTCAAGAC TCAATGTGGAAAAAATATTTTAAACTACTGATTGAATGTTAATGGTCAATGCTAGCACAATATTCCTATGCTGCAATACATTAAAATAAC TAAGCAAGTATATTTATTTCTAGCAAACAGATGTTTGTTTTCAAAATACTTCTTTTTCATTATTGGTTTTAAAAAAGCATTATCCTTTTA TCTCACAAATAAGTAATATCTTTCAGTTATTAAATGATAGATAATGCCTTTTTGGTTTTGTGTGGTATTCAACTAATACATGGTTTAAAG TCACAGCCGTTTGAATATATTTTATCTTGGTAGTACATTTTCTCCCTTAGGAATATACATAGTCTTTGTTTACATGAGTTCAAATACTTT TGGGATGTTACCTTCACATGTCCTATTACTGATGTGTGCAACCTTTTATGTGTTGATGACTCACTCATAAAGGTTTTTGTCTACTGTCAT TTGTTCTTTCCACTTATTCTAAGCATTTAGAGTAATAGAGTCATACTTTTTTATAACAGCAACCTTTTAAAAGGAAAGCTCTTATAAAGT CACTGTCATGTTTTAGTTGACTAAATATAAATTTAAGAGAATACTTGAATTGTGCTATAGTAAATAAAAATTTACTATTTTGTGTTTGAA TATTGAAAAATTGAATCACTTTAACTCCTGAAAAACATACAATTGTAATTTCAATGTAAAATTTCTTATGTAGGTACTACCTTTTTTTAT CGTTCCAAGGTTTGCTAGTGAACACAGGATATTTTAAAAGTTTTTTATTCTTCGGGCCTGGAAAGTGTACAAAGTCAGTGTAGGAGAAAA AAATCCATATTTTTATATTAGCATGCACACTAAAAACCAAAATATTATTCATACTTAAAACATTCATACAAAACAATATGTAAGCAGAAA TAGTACTAAAATACTTTGCCTAATTTCTAAGTTGAAGAATAACACTGGGACACAGTTTTTTCATATGAGAGAATATTCCGCTATTTCAAA TTTAAGGGATTTTCTTCCTAACATTGAAATTTTAAAAACAGAGTTACTTCTAAATAATTATACAGATTTTTTCTTCTATTAAATATTATT ATTTAGAATTGTTTTTGTATTACATATTCATGTTAAGAACCCCGTCTTCCCTTAAAATACATTAAAATTATGACATTTTTGCTTTGTGAT TGAATTTCAAATAGCAGTATGGTATCCTTTTATCTAGTTAATATATGAAAGTGGCTTGAATATAGTCAAATCCATTTTAGGTACTCTACT GACTTTTTCCTTCACTTGCCAAGCCCTTTTATTGTTCACTGTTAGAAAAATAGAGAAGGTGAGACAGCTGGGGGAAAATGTGGAGTAAAT GATAATCAAATGTTGAATTCTAAAAGTCTCTACATTTACCTAGGTTGGCTTTCTCCCCCAGTTCAGAAGTTTCCAGCTTGGCCAATCATC AGAATCACTTGAGGAACTTAGAAAGAACTCCCTGGCTGTAGCTCCTATGTAGGTTTAGGTTGAGACTCTGGATTCCACAATTTTTAAAGG TTACCATCTGAGGTTTCTGATCATAGTCTACTTTTGAAGCAGCTGCTGCTGTTTCTTTATTCCATTGAACACCCTGGAATTGACATAATT TTATCTATCAGCATTTCTCCCCTTTTAGTTTATTTAATAATTAACCCGGTCTCCAGGGCAGTTTTCATATGACCATGTGTATATTCACTG CTCACGAAAAAGTTTAATGTTAGATTACCAAATTTAATATAGTTACAGAATTACTGCATAAGGGCTTCCCTTCTTGGAGACTCTTACCCA GCATGGGAACAGTGATCTGCCCACATGACAGGGTGGTATGCCAGGCATAGTTAACTGCTTTTGGTTGTGAGGTACTCATCTTCCTTTAGT TACCCTTAGTTATGTGGCACACATGTCCTTATTGCCTAGTTCGTCATCCACACTTTGGATCTTGTGAAAATGCTGTTAGTATCCAACCTT AAAATATATTAGTATATGGGTTTTTATTAAAAGAATTACTTTGAATTTTCTATTTAATTCATATGTAAATAAAGGAACATTTCATTTCAC TTAAAAAAATTATATCAGTTATTAGGCTGGGTGCAGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGCGGGTGGATTACCA GAGTTCGGGAGTTTGAGACCAGCTTGACCAACATGGAGAAACCCCGTCTCTACTAAAAATACAAAATTAGCCAGGTGTGGTGGCGCATGC CTGTAATCCTGGCTACTCAGGAGGCTGAGGCAGGAGAATCGCTTGAAAACCCAGGAGACAGAGGTTGCGGTGAGCTGAGATTGCGCCATT GTACTCCAGCCTGGGCAAGAAGAGCGAAACTCTGTCTCCAAAAAAAAAAAAAAAAAAATTATTAATACTTTTAAAGACTGAGCTGTTTAA GAATTTTTTGGGGAACATTTCTAGCAGTGATTTTTTTGGCCTTTAATGATAGCGTAAAGACAGGAGCCTTACAACTTAGGCAAAGCATTT CACATGCAGTCCTTCTTCCATCTCAAAATATGTACTTATTTTACATACAGAATTTTACACTAACCATTGAAAAATAAAGTAGGATCTGCT ACAGTTTCACCTGAAAATTTATAAAAAGTGTTGAGATTGGTAGAAGGTAGTTTTTAAGTACATGTGCACTACCCTAAAAGACTTGTCTAT TGTCAATAAAGTGTTAGTATTTGTGAAATTATTATTCCTGTTCAGAAATACTATTTCTTAAATCTCCTGGGAATTTGTGGCATAATAAAG CACATTCAAAGTTCTAATGTATTTATGAGCTCATTTTCAAAATAGTAAGTTTGTCATCTTTAAAATGAACATGACTTGCCTCCTTGATTT CTGAAATGAATTAATTGAAGATTGCTATAGTAATCTTTATTTCATCTTTCTAGAGTTGTTGACAATTTTATTATACAACAGTTACCATTA GAGAAGGAGGGAAGGGCTTTTGGGTGTGTATTTATAGGTACTAAGGGATTTACTAAATATAGTAGATTAGCACTGTCACACTTGTTCAAG TAGTTTCAAACATAGAAAATTAAGTATCAGGTATGTGGAGCAATGTAGTTTTTTTTTTTCTTCAGTTTAAAAAATTTTTAATTGTGGTAG AAGCAATGTATTCTTAAGGTGAAAAACCTACCTCGGTTACATGTGGTTTGTGTTTTTTGGATTAATCTGGATTTTATAATTAGAAATAAA AATGTAAGATTTTGAATCCACTTAATTTCTTGAAAATAGTACAAGTCAGTGTAATAGAGAAGCATTCATATATTCAACACTGTAAGACAA AACAGCAGAGACCTTGGATTTGATAATTGATCTGATATCCTGGACAGTATTCATATGTACAGTGATAGGTATCTTTCTTTGGAGTTTTTT TTTTGTGCATATGTGTATAGTTTTATGGGTTCTGAGTTGGTGACCAGTAAGTTGCATGTAGTGCTGGCACTTACTTAATAACTATTCATG ATATTGTTAATAACTTGTTATAGGATTGTATTCCCAATTACAGTCTCTAAGATTGTAATTGATATTATCTGAGAGGTAGTGTGACAACTT TCTTTTGTTGTTACATTAAGCCGAAAACATAATACTAATAGACAACTAACAGTTTGCTTATCAGGCACATCAACTAAGGCACCTCCCCCC ATGCTAAGTTTCTCCTGGATATATGGAAGTTGATTGTTTCCCAGTTTAAAAACTTGAACTAATATCTCCTAAGAAAATCTGAGTCCATAT TGTTTTTATTTTACTTAGCTAGAATCTCATAGCATGTTAAAGTCATATCCTTATCCCCACTAAAAATAACTATGTCTATGTGAGAGGAAT ATAGTATGTGGGAGCTGTATTAAATACTATTACAGGTGTTACAGAATCTTTAAATAAATGGACATGGACCAACTTTCCATCTAGTAGTGT ACGATCTATATAGTGCATGTCAGTAGCACAAAATGCAGTCTTAGCATTAGCCTGTCTAATCTGAATAGTTTACTCAAAAGTACTTCTTTG TGTTAAGTATTCAGCCACTGTTTTTAGATCTAGTTAATAGGTTCTATTTAATTTGCTACAACATTTACTGAATGGTGGAGTGAAAAAACT GATGCATACTGGGAAATATCTACCATTTTTTAAAGATAATGTTAATTAGGAAAAGAACACTTTTAAGGAATTTATAGCAGTGATGAAATG AATTCAGTTATATCAGATACACCAAACTGTTGATGGTATTTAAATGTGACTTCAAGTTAGTATTTCTGTATATATTATTGATTACTGGTT TGTTTTTAGATATGTAAGTCTGTTCTAATCTACAGTTCACATATCGACAGTTACTCTGGTAATAATAGAATGTTAGTGATGATCACTTGG TGGATGTTGATTAAGTGCCTGTGTTTTGTTTCCTCCTCTGGATACCAAATAGGTGTATGCTACTTTTTTGGTGAACTTATTTCTTGGAAG ATTTGGCTATGCTATTCAGGGTTTTTATTCTTATGTTTTTCTTCTAAATTTAAGTAGCATCCTGCTGCTACCATATTAAAGCTAAAATTT AACTTTTGCTGAAGAATCAGCTAATTCAGGTAATCCAAATATTTGTGGAAAAACATCTGGATAATTTATTGAACACATTAGTATTGTGTT AGACAGCTTTGATCATTCCCATTTCATAGGTTTTTATTGTGGAATAGTCAACTTAATATAGATTCACTTTCAATTTGCATGTATAAAGTA ATACTCAATAAAATTTTTTTCATTTATTTTTCAACAGTGGTTATTTTTTTTCTTCCTGTACTATCAGTAAAATCCTGACTATGAGTTTTA CTTTTGAAGCTAAAGGATAATGCTGGTAATCTAATTATGTACCTCTTACAGAAACCATATGCAGCACTTTAAAAATCTTTATTTGGTATA TTATTTTAGGTGGACAATGATTTAAGACTCAAAGCCATCATATTAAGGTCTAAATACATTAGTGGTGGGGTTTCTCGAATAAATGAGGAA GTGCACAAAAGTTCAGCCTGACTGAAAATTTTAATTGTGTTTTAAAACTACATGAATAATTTCTTGATTCAAAATCAGAACTCTTATAAA CTAAATCTGATGGTGTCCAAAGAATTTCAGGTCCTTCAAAGTTTGTAAAAGATAAGTAGGGGCCTAGGAATATAAAAATTTAGACTTTTT TAGTAAATGGTTTACATAACCTTTTGTCTTAATTTGTCATTCTTCATACACAGGCACAAGCTAATCAGTCTTCTCTACTTCTAGAACTCT AAATCTTCTCAGTAATGTCATACAAGTCTAACAAGAGGAAAAGCATCCTTAAGTCAGTCTATTTAGATAAACTCTTCAAGTCCCTATATA AGGACGTATTCCACTAGCAAGCCAGTAAATTTTTCCAAGGTCACATAATCTTACATGAAATGGAACCTTTCATCTTAGACTTCATCAAAC TCAATTTTTTCCCTTCTAGATTCACTTTGTGTTTATGCATGCATGCACGCGTGCACACAATTCTATCAGCAGCTGTAAACTACCCACATA TTTTCTTAATCTCATTTTTTCAGTTTTTCTTCATCTTTAAAAGAGGTTACATTTCATTCCTGGTCAACTCTTAAAAAGAATTATGTAATG TTGGGCCTTCATATTAAAGAGAGAGACTGGTTATAAGATCCTTTACAGTCCATTCATTTTATTCTGATGTCTAACCAGATAGACACTAGC AAGCAAAACTTCCCTCTTAATCCTGGACCAAATGCATAATTTTACTGTCACTTTCAAAAATCTGTTATGACTGAATCAAAATCCTTTTAA AGAAAGGAAAAAGCTCCTTTTGTGTCAAATAGTTGAACAACATGAAAACAGTATGAGCCGGTTAAAGATAGATTGAATTTTTACTTTACA CATATGAAAAACAGTAAGTTTTGACTGCTGTGTATGTTATTCATGTTAATATGTGCTCAGTTATTCACTATTGTTAATCCACATATAATC AGTTGCTATCCCTGGTTAGACACACTATGGAACTTGAAATGCACAATATTTACATTGTTAGAGGCTTCTATCCAAATATCTGCATTCCTT TAAAATGTGAACTATTTGCTGTGATTAACCAAAGGTAGATTATGTCATCAGTGGACATTTTAGCTTTATGGAAACAAATTATTAAGAAAT GAATAGAAAGGTGTCTTTTTCTTTGTGTAGTGCAAAAGCCTAAAGCTATCAGTCAAAGGCCTAAGAAATCCACATTTGAAAAACGTAAAT CATGATTGGTAAGAATACATTCATCTGATAGTATTGAGAAAAGTTGAAAAACTGTTAGCCTTCCATAACACATTAAACATTTTATGTATG GATGGCTGAAAGTATTGAGAAAAGCTGAAAAACTGTTAGCCTTCCATAACACATTAAACGTTTTGTGTATGGATGGCTTAGGACAATAAA CAACATCATTAAAGTAAAATTATGTCAGTCTGTTCATATTAACTTATTTAAATCAATGAAAATTTTGATGAGATGACTAAATGGATGCTT TGGAAATGCAGGATTATAGGAGGCCTAAAAGTGCATCTTGTTTCTTGTAACCCTTTTAAAACCAATATGCCTGGCTAGGTGCAGTGGCTC ATGCCTGTAATACCAACGGGGTAACACAGGGTTATGCCGTCTATACAAAAAAATAAATGAGCTGGGCAAGATGGCATGCACCTGTAGTCC CAGCTGCTTGGTAGGCTGAGGGGGAAGGATTGCTTGAGCCTGGGAGGTCGAGACTGCAGTGAGCCAAGATCACACCACTGCACTCCAGCC TGGGTGACAGAGCAAGACTCTACCTCAAAAATAAAAATAATCAATATAGTTTCAATGAAGCAAAGCATCTCAGGTAACAATTTGAGCATA ACTTTAACCATAACTTATGATAGCATAATAACATTCATTAGTAATTCAGTAGCCGTATGTGCCAGGCTGTGTTAGGTGCTTTATATATTG TTTAATTTTTAAAAACTTGTGGAGTGTACAGATTGGTAAGGTGACATTGTATCACAAAGCTAGTCTTTGAGTCCAAAGTTTTGTGGTTTT ATGTTATGATATACTTTTATCATGGAATTGTCTTATTAAATGTTTTGCCAGTGGTTCTTAAAGTGTGTTTCTGACACCAGTAGCATTGAC TTCACTTAGAAACCTGTTAGAAATACAAATTATTTGGCCCCACCCAACACTTGAGTCACAAACTTTGCAGATGGGGCTCAATCTGTTTTA ACAAGCGCTTCATGTAATTTTGATGCAGGCCTAAGTTTTTGAGCCACTGCAGTATGCATTTCTATTTTTAAGCAAAGATCTTGGTCTTTC TTTTTGGACATTGTAGAAATAACATGAACTTGTTTTTTGTTTGTTTTTGTTTTGTTTTGTTTTAAGCTCCTGATCTTTGTTGGTTATGTT GCAAAAGATTGTATCAGGAGAAGCCTCAGCATGGACATTGGCATCCTGACATAACCCCCATTAATTTAGTATTCTTTCTGAAACTCAAAT GGATTCTCAAGTCCAAGAGACTATGGAATAAAATCATTGTTTGTCTGTGTTAAGTTTTATCTCTGTTATTGCCTGAAGACTTTTGGTAAC >13523_13523_2_CCAR1-PAWR_CCAR1_chr10_70546400_ENST00000535016_PAWR_chr12_79988215_ENST00000328827_length(amino acids)=930AA_BP=912 MAQFGGQKNPPWATQFTATAVSQPAALGVQQPSLLGASPTIYTQQTALAAAGLTTQTPANYQLTQTAALQQQAAAAAAALQQLQQPQQTL LTQPAVALPTSLSLSTPQPTAQITVSYPTPRSSQQQTQPQKQRVFTGVVTKLHDTFGFVDEDVFFQLSAVKGKTPQVGDRVLVEATYNPN MPFKWNAQRIQTLPNQNQSQTQPLLKTPPAVLQPIAPQTTFGVQTQPQPQSLLQAQISAASITPLLQTQPQPLLQQPQQKAGLLQPPVRI VSQPQPARRLDPPSRFSGRNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVRRVVPRYTVQFSKFSLDCPS CDMMELRRRYQNLYIPSDFFDAQFTWVDAFPLSRPFQLGNYCNFYVMHREVESLEKNMAILDPPDADHLYSAKVMLMASPSMEDLYHKSC ALAEDPQELRDGFQHPARLVKFLVGMKGKDEAMAIGGHWSPSLDGPDPEKDPSVLIKTAIRCCKALTGIDLSVCTQWYRFAEIRYHRPEE THKGRTVPAHVETVVLFFPDVWHCLPTRSEWETLSRGYKQQLVEKLQGERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKVNDLR KELESRALSSKGLKSQLIARLTKQLKVEEQKEEQKELEKSEKEEDEDDDRKSEDDKEEEERKRQEEIERQRRERRYILPDEPAIIVHPNW AAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVSLFAELFNEMLQRDFGVRIYKSLLSLPEKEDKKEKDKKSKKDERKDKKEERDDETDEP KPKRRKSGDDKDKKEDRDERKKEDKRKDDSKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDKRDINRYCKERPSKDKFGRN -------------------------------------------------------------- >13523_13523_3_CCAR1-PAWR_CCAR1_chr10_70546400_ENST00000543719_PAWR_chr12_79988215_ENST00000328827_length(transcript)=10775nt_BP=2850nt TGCGCCTAAAGCTGACGGGTTTGAAATGGCTTCGATGTTAGCCGGGACCCGACTCAGGTGAAGATCGATGCTATAGAAGACAAACAAGGG AAGGTTTTTTTTCCTTTTGCATCATGGCTCAATTTGGAGGACAGAAGAATCCGCCATGGGCTACTCAGTTTACAGCCACTGCAGTATCAC AGCCAGCTGCACTGGGTGTTCAACAGCCATCACTCCTTGGAGCATCTCCTACCATTTATACACAGCAAACTGCATTGGCAGCAGCAGGCC TTACCACACAAACTCCAGCAAACTATCAGTTAACACAAACTGCTGCATTGCAGCAACAAGCCGCAGCTGCAGCAGCTGCATTACAACAGT TACAGCAACCCCAGCAAACCCTCTTAACACAGCCAGCTGTTGCACTGCCTACAAGCCTTAGCCTGTCTACTCCTCAGCCAACAGCACAAA TAACTGTATCATATCCAACACCAAGGTCCAGTCAACAGCAAACCCAGCCTCAGAAGCAGCGTGTTTTCACAGGGGTGGTTACAAAACTAC ATGATACGTTTGGATTTGTGGATGAAGATGTATTCTTTCAGCTTAGTGCTGTCAAAGGGAAAACCCCCCAAGTAGGTGACAGAGTATTGG TTGAAGCTACTTATAATCCTAATATGCCTTTTAAATGGAATGCACAGAGAATTCAAACACTACCAAATCAGAATCAGTCGCAAACCCAGC CATTACTGAAGACTCCTCCTGCTGTACTTCAGCCAATTGCACCACAGACAACATTTGGTGTTCAGACTCAGCCCCAGCCCCAGTCACTGC TGCAGGCACAGATTTCAGCAGCTTCTATTACACCACTATTGCAGACTCAACCACAGCCCTTATTACAGCAGCCTCAGCAAAAAGCTGGTT TATTGCAGCCTCCTGTTCGTATAGTTTCACAGCCACAACCGGCACGACGATTAGATCCCCCATCCCGATTTTCAGGAAGAAATGACAGAG GGGATCAAGTGCCTAACAGAAAAGATGATCGAAGTCGTGAGAGAGAGAGAGAAAGACGTAGATCGAGAGAAAGATCACCTCAGAGGAAAC GTTCCCGGGAAAGATCTCCACGAAGAGAGCGAGAGCGATCACCTCGGAGAGTTCGACGTGTTGTTCCACGTTACACAGTTCAGTTTTCAA AGTTTTCTTTAGATTGTCCCAGTTGTGACATGATGGAACTAAGGCGCCGTTATCAAAATTTGTATATACCTAGTGACTTTTTTGATGCTC AATTTACATGGGTGGATGCTTTCCCTTTGTCAAGACCATTTCAGCTGGGAAATTACTGCAATTTTTATGTAATGCACAGAGAAGTAGAGT CCTTAGAAAAAAATATGGCCATTCTTGATCCACCAGATGCTGACCACTTATACAGTGCAAAGGTAATGCTGATGGCTAGCCCTAGTATGG AAGATTTATATCATAAGTCATGTGCTCTTGCTGAGGACCCACAAGAACTTCGAGATGGATTCCAACATCCTGCTAGACTTGTTAAGTTTT TAGTGGGCATGAAAGGCAAGGATGAAGCTATGGCCATTGGAGGCCACTGGTCTCCTTCGTTGGATGGACCAGACCCAGAAAAAGATCCCT CTGTGTTGATTAAGACTGCTATTCGTTGTTGTAAGGCTCTGACAGGCATTGATCTAAGTGTGTGCACACAATGGTACCGTTTTGCAGAGA TTCGCTACCATCGCCCTGAGGAGACCCACAAGGGGCGTACAGTTCCAGCTCATGTGGAGACAGTGGTTTTATTTTTCCCGGATGTTTGGC ATTGCCTTCCCACCCGCTCAGAGTGGGAAACCCTCTCCCGAGGATACAAGCAGCAGCTGGTCGAGAAGCTTCAGGGTGAACGCAAGGAGG CTGATGGAGAACAGGATGAAGAAGAGAAGGATGATGGTGAAGCTAAAGAAATTTCTACACCTACCCATTGGTCTAAACTTGATCCAAAGA CAATGAAGGTAAATGACCTCCGAAAAGAATTAGAAAGTCGAGCTCTTAGTTCCAAAGGATTAAAATCCCAGTTAATAGCCCGATTGACAA AACAGCTTAAAGTAGAGGAACAAAAAGAAGAACAGAAGGAGTTAGAGAAATCTGAAAAAGAAGAGGATGAGGATGATGATAGGAAATCTG AAGACGATAAAGAGGAAGAAGAAAGGAAACGTCAAGAGGAAATAGAACGCCAGCGTCGAGAAAGAAGATATATTTTGCCTGATGAACCGG CCATCATTGTACATCCAAATTGGGCTGCAAAAAGTGGCAAGTTTGATTGTAGCATCATGTCTTTGAGTGTCCTATTGGACTACAGATTAG AGGATAATAAAGAACATTCATTTGAGGTTTCATTGTTTGCGGAACTTTTCAACGAAATGCTTCAAAGAGATTTTGGTGTCCGTATATACA AATCATTACTGTCTCTTCCTGAGAAAGAGGACAAAAAAGAAAAGGATAAAAAAAGCAAAAAAGATGAGAGAAAAGATAAAAAAGAAGAAA GAGATGATGAAACTGATGAACCAAAACCCAAACGGAGAAAATCAGGCGATGATAAAGATAAAAAAGAAGATAGAGATGAAAGGAAGAAAG AAGATAAAAGAAAAGATGATTCTAAAGATGATGATGAAACTGAAGAAGATAACAATCAAGATGAATATGACCCTATGGAAGCAGAAGAAG CTGAGGATGAAGAAGATGATAGGGATGAGGAAGAAATGACCAAACGAGATGACAAAAGAGATATCAACAGATACTGCAAGGAGAGGCCCT CTAAAGATAAGTTTGGAAGAAATACTTTATACTCTTGGACTACATCTTTCTCGGGCTCAGGAAGTAGTAAGAGAAAGACAAGAAAACCTA AGACTTGTGAGACTGATGCAAGATAAAGAGGAAATGATTGGAAAACTCAAAGAAGAAATTGATTTATTAAATAGAGACCTAGATGACATA GAAGATGAAAATGAACAGCTAAAGCAGGAAAATAAAACTCTTTTGAAAGTTGTGGGTCAGCTGACCAGGTAGAGGATTCAAGACTCAATG TGGAAAAAATATTTTAAACTACTGATTGAATGTTAATGGTCAATGCTAGCACAATATTCCTATGCTGCAATACATTAAAATAACTAAGCA AGTATATTTATTTCTAGCAAACAGATGTTTGTTTTCAAAATACTTCTTTTTCATTATTGGTTTTAAAAAAGCATTATCCTTTTATCTCAC AAATAAGTAATATCTTTCAGTTATTAAATGATAGATAATGCCTTTTTGGTTTTGTGTGGTATTCAACTAATACATGGTTTAAAGTCACAG CCGTTTGAATATATTTTATCTTGGTAGTACATTTTCTCCCTTAGGAATATACATAGTCTTTGTTTACATGAGTTCAAATACTTTTGGGAT GTTACCTTCACATGTCCTATTACTGATGTGTGCAACCTTTTATGTGTTGATGACTCACTCATAAAGGTTTTTGTCTACTGTCATTTGTTC TTTCCACTTATTCTAAGCATTTAGAGTAATAGAGTCATACTTTTTTATAACAGCAACCTTTTAAAAGGAAAGCTCTTATAAAGTCACTGT CATGTTTTAGTTGACTAAATATAAATTTAAGAGAATACTTGAATTGTGCTATAGTAAATAAAAATTTACTATTTTGTGTTTGAATATTGA AAAATTGAATCACTTTAACTCCTGAAAAACATACAATTGTAATTTCAATGTAAAATTTCTTATGTAGGTACTACCTTTTTTTATCGTTCC AAGGTTTGCTAGTGAACACAGGATATTTTAAAAGTTTTTTATTCTTCGGGCCTGGAAAGTGTACAAAGTCAGTGTAGGAGAAAAAAATCC ATATTTTTATATTAGCATGCACACTAAAAACCAAAATATTATTCATACTTAAAACATTCATACAAAACAATATGTAAGCAGAAATAGTAC TAAAATACTTTGCCTAATTTCTAAGTTGAAGAATAACACTGGGACACAGTTTTTTCATATGAGAGAATATTCCGCTATTTCAAATTTAAG GGATTTTCTTCCTAACATTGAAATTTTAAAAACAGAGTTACTTCTAAATAATTATACAGATTTTTTCTTCTATTAAATATTATTATTTAG AATTGTTTTTGTATTACATATTCATGTTAAGAACCCCGTCTTCCCTTAAAATACATTAAAATTATGACATTTTTGCTTTGTGATTGAATT TCAAATAGCAGTATGGTATCCTTTTATCTAGTTAATATATGAAAGTGGCTTGAATATAGTCAAATCCATTTTAGGTACTCTACTGACTTT TTCCTTCACTTGCCAAGCCCTTTTATTGTTCACTGTTAGAAAAATAGAGAAGGTGAGACAGCTGGGGGAAAATGTGGAGTAAATGATAAT CAAATGTTGAATTCTAAAAGTCTCTACATTTACCTAGGTTGGCTTTCTCCCCCAGTTCAGAAGTTTCCAGCTTGGCCAATCATCAGAATC ACTTGAGGAACTTAGAAAGAACTCCCTGGCTGTAGCTCCTATGTAGGTTTAGGTTGAGACTCTGGATTCCACAATTTTTAAAGGTTACCA TCTGAGGTTTCTGATCATAGTCTACTTTTGAAGCAGCTGCTGCTGTTTCTTTATTCCATTGAACACCCTGGAATTGACATAATTTTATCT ATCAGCATTTCTCCCCTTTTAGTTTATTTAATAATTAACCCGGTCTCCAGGGCAGTTTTCATATGACCATGTGTATATTCACTGCTCACG AAAAAGTTTAATGTTAGATTACCAAATTTAATATAGTTACAGAATTACTGCATAAGGGCTTCCCTTCTTGGAGACTCTTACCCAGCATGG GAACAGTGATCTGCCCACATGACAGGGTGGTATGCCAGGCATAGTTAACTGCTTTTGGTTGTGAGGTACTCATCTTCCTTTAGTTACCCT TAGTTATGTGGCACACATGTCCTTATTGCCTAGTTCGTCATCCACACTTTGGATCTTGTGAAAATGCTGTTAGTATCCAACCTTAAAATA TATTAGTATATGGGTTTTTATTAAAAGAATTACTTTGAATTTTCTATTTAATTCATATGTAAATAAAGGAACATTTCATTTCACTTAAAA AAATTATATCAGTTATTAGGCTGGGTGCAGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGCGGGTGGATTACCAGAGTTC GGGAGTTTGAGACCAGCTTGACCAACATGGAGAAACCCCGTCTCTACTAAAAATACAAAATTAGCCAGGTGTGGTGGCGCATGCCTGTAA TCCTGGCTACTCAGGAGGCTGAGGCAGGAGAATCGCTTGAAAACCCAGGAGACAGAGGTTGCGGTGAGCTGAGATTGCGCCATTGTACTC CAGCCTGGGCAAGAAGAGCGAAACTCTGTCTCCAAAAAAAAAAAAAAAAAAATTATTAATACTTTTAAAGACTGAGCTGTTTAAGAATTT TTTGGGGAACATTTCTAGCAGTGATTTTTTTGGCCTTTAATGATAGCGTAAAGACAGGAGCCTTACAACTTAGGCAAAGCATTTCACATG CAGTCCTTCTTCCATCTCAAAATATGTACTTATTTTACATACAGAATTTTACACTAACCATTGAAAAATAAAGTAGGATCTGCTACAGTT TCACCTGAAAATTTATAAAAAGTGTTGAGATTGGTAGAAGGTAGTTTTTAAGTACATGTGCACTACCCTAAAAGACTTGTCTATTGTCAA TAAAGTGTTAGTATTTGTGAAATTATTATTCCTGTTCAGAAATACTATTTCTTAAATCTCCTGGGAATTTGTGGCATAATAAAGCACATT CAAAGTTCTAATGTATTTATGAGCTCATTTTCAAAATAGTAAGTTTGTCATCTTTAAAATGAACATGACTTGCCTCCTTGATTTCTGAAA TGAATTAATTGAAGATTGCTATAGTAATCTTTATTTCATCTTTCTAGAGTTGTTGACAATTTTATTATACAACAGTTACCATTAGAGAAG GAGGGAAGGGCTTTTGGGTGTGTATTTATAGGTACTAAGGGATTTACTAAATATAGTAGATTAGCACTGTCACACTTGTTCAAGTAGTTT CAAACATAGAAAATTAAGTATCAGGTATGTGGAGCAATGTAGTTTTTTTTTTTCTTCAGTTTAAAAAATTTTTAATTGTGGTAGAAGCAA TGTATTCTTAAGGTGAAAAACCTACCTCGGTTACATGTGGTTTGTGTTTTTTGGATTAATCTGGATTTTATAATTAGAAATAAAAATGTA AGATTTTGAATCCACTTAATTTCTTGAAAATAGTACAAGTCAGTGTAATAGAGAAGCATTCATATATTCAACACTGTAAGACAAAACAGC AGAGACCTTGGATTTGATAATTGATCTGATATCCTGGACAGTATTCATATGTACAGTGATAGGTATCTTTCTTTGGAGTTTTTTTTTTGT GCATATGTGTATAGTTTTATGGGTTCTGAGTTGGTGACCAGTAAGTTGCATGTAGTGCTGGCACTTACTTAATAACTATTCATGATATTG TTAATAACTTGTTATAGGATTGTATTCCCAATTACAGTCTCTAAGATTGTAATTGATATTATCTGAGAGGTAGTGTGACAACTTTCTTTT GTTGTTACATTAAGCCGAAAACATAATACTAATAGACAACTAACAGTTTGCTTATCAGGCACATCAACTAAGGCACCTCCCCCCATGCTA AGTTTCTCCTGGATATATGGAAGTTGATTGTTTCCCAGTTTAAAAACTTGAACTAATATCTCCTAAGAAAATCTGAGTCCATATTGTTTT TATTTTACTTAGCTAGAATCTCATAGCATGTTAAAGTCATATCCTTATCCCCACTAAAAATAACTATGTCTATGTGAGAGGAATATAGTA TGTGGGAGCTGTATTAAATACTATTACAGGTGTTACAGAATCTTTAAATAAATGGACATGGACCAACTTTCCATCTAGTAGTGTACGATC TATATAGTGCATGTCAGTAGCACAAAATGCAGTCTTAGCATTAGCCTGTCTAATCTGAATAGTTTACTCAAAAGTACTTCTTTGTGTTAA GTATTCAGCCACTGTTTTTAGATCTAGTTAATAGGTTCTATTTAATTTGCTACAACATTTACTGAATGGTGGAGTGAAAAAACTGATGCA TACTGGGAAATATCTACCATTTTTTAAAGATAATGTTAATTAGGAAAAGAACACTTTTAAGGAATTTATAGCAGTGATGAAATGAATTCA GTTATATCAGATACACCAAACTGTTGATGGTATTTAAATGTGACTTCAAGTTAGTATTTCTGTATATATTATTGATTACTGGTTTGTTTT TAGATATGTAAGTCTGTTCTAATCTACAGTTCACATATCGACAGTTACTCTGGTAATAATAGAATGTTAGTGATGATCACTTGGTGGATG TTGATTAAGTGCCTGTGTTTTGTTTCCTCCTCTGGATACCAAATAGGTGTATGCTACTTTTTTGGTGAACTTATTTCTTGGAAGATTTGG CTATGCTATTCAGGGTTTTTATTCTTATGTTTTTCTTCTAAATTTAAGTAGCATCCTGCTGCTACCATATTAAAGCTAAAATTTAACTTT TGCTGAAGAATCAGCTAATTCAGGTAATCCAAATATTTGTGGAAAAACATCTGGATAATTTATTGAACACATTAGTATTGTGTTAGACAG CTTTGATCATTCCCATTTCATAGGTTTTTATTGTGGAATAGTCAACTTAATATAGATTCACTTTCAATTTGCATGTATAAAGTAATACTC AATAAAATTTTTTTCATTTATTTTTCAACAGTGGTTATTTTTTTTCTTCCTGTACTATCAGTAAAATCCTGACTATGAGTTTTACTTTTG AAGCTAAAGGATAATGCTGGTAATCTAATTATGTACCTCTTACAGAAACCATATGCAGCACTTTAAAAATCTTTATTTGGTATATTATTT TAGGTGGACAATGATTTAAGACTCAAAGCCATCATATTAAGGTCTAAATACATTAGTGGTGGGGTTTCTCGAATAAATGAGGAAGTGCAC AAAAGTTCAGCCTGACTGAAAATTTTAATTGTGTTTTAAAACTACATGAATAATTTCTTGATTCAAAATCAGAACTCTTATAAACTAAAT CTGATGGTGTCCAAAGAATTTCAGGTCCTTCAAAGTTTGTAAAAGATAAGTAGGGGCCTAGGAATATAAAAATTTAGACTTTTTTAGTAA ATGGTTTACATAACCTTTTGTCTTAATTTGTCATTCTTCATACACAGGCACAAGCTAATCAGTCTTCTCTACTTCTAGAACTCTAAATCT TCTCAGTAATGTCATACAAGTCTAACAAGAGGAAAAGCATCCTTAAGTCAGTCTATTTAGATAAACTCTTCAAGTCCCTATATAAGGACG TATTCCACTAGCAAGCCAGTAAATTTTTCCAAGGTCACATAATCTTACATGAAATGGAACCTTTCATCTTAGACTTCATCAAACTCAATT TTTTCCCTTCTAGATTCACTTTGTGTTTATGCATGCATGCACGCGTGCACACAATTCTATCAGCAGCTGTAAACTACCCACATATTTTCT TAATCTCATTTTTTCAGTTTTTCTTCATCTTTAAAAGAGGTTACATTTCATTCCTGGTCAACTCTTAAAAAGAATTATGTAATGTTGGGC CTTCATATTAAAGAGAGAGACTGGTTATAAGATCCTTTACAGTCCATTCATTTTATTCTGATGTCTAACCAGATAGACACTAGCAAGCAA AACTTCCCTCTTAATCCTGGACCAAATGCATAATTTTACTGTCACTTTCAAAAATCTGTTATGACTGAATCAAAATCCTTTTAAAGAAAG GAAAAAGCTCCTTTTGTGTCAAATAGTTGAACAACATGAAAACAGTATGAGCCGGTTAAAGATAGATTGAATTTTTACTTTACACATATG AAAAACAGTAAGTTTTGACTGCTGTGTATGTTATTCATGTTAATATGTGCTCAGTTATTCACTATTGTTAATCCACATATAATCAGTTGC TATCCCTGGTTAGACACACTATGGAACTTGAAATGCACAATATTTACATTGTTAGAGGCTTCTATCCAAATATCTGCATTCCTTTAAAAT GTGAACTATTTGCTGTGATTAACCAAAGGTAGATTATGTCATCAGTGGACATTTTAGCTTTATGGAAACAAATTATTAAGAAATGAATAG AAAGGTGTCTTTTTCTTTGTGTAGTGCAAAAGCCTAAAGCTATCAGTCAAAGGCCTAAGAAATCCACATTTGAAAAACGTAAATCATGAT TGGTAAGAATACATTCATCTGATAGTATTGAGAAAAGTTGAAAAACTGTTAGCCTTCCATAACACATTAAACATTTTATGTATGGATGGC TGAAAGTATTGAGAAAAGCTGAAAAACTGTTAGCCTTCCATAACACATTAAACGTTTTGTGTATGGATGGCTTAGGACAATAAACAACAT CATTAAAGTAAAATTATGTCAGTCTGTTCATATTAACTTATTTAAATCAATGAAAATTTTGATGAGATGACTAAATGGATGCTTTGGAAA TGCAGGATTATAGGAGGCCTAAAAGTGCATCTTGTTTCTTGTAACCCTTTTAAAACCAATATGCCTGGCTAGGTGCAGTGGCTCATGCCT GTAATACCAACGGGGTAACACAGGGTTATGCCGTCTATACAAAAAAATAAATGAGCTGGGCAAGATGGCATGCACCTGTAGTCCCAGCTG CTTGGTAGGCTGAGGGGGAAGGATTGCTTGAGCCTGGGAGGTCGAGACTGCAGTGAGCCAAGATCACACCACTGCACTCCAGCCTGGGTG ACAGAGCAAGACTCTACCTCAAAAATAAAAATAATCAATATAGTTTCAATGAAGCAAAGCATCTCAGGTAACAATTTGAGCATAACTTTA ACCATAACTTATGATAGCATAATAACATTCATTAGTAATTCAGTAGCCGTATGTGCCAGGCTGTGTTAGGTGCTTTATATATTGTTTAAT TTTTAAAAACTTGTGGAGTGTACAGATTGGTAAGGTGACATTGTATCACAAAGCTAGTCTTTGAGTCCAAAGTTTTGTGGTTTTATGTTA TGATATACTTTTATCATGGAATTGTCTTATTAAATGTTTTGCCAGTGGTTCTTAAAGTGTGTTTCTGACACCAGTAGCATTGACTTCACT TAGAAACCTGTTAGAAATACAAATTATTTGGCCCCACCCAACACTTGAGTCACAAACTTTGCAGATGGGGCTCAATCTGTTTTAACAAGC GCTTCATGTAATTTTGATGCAGGCCTAAGTTTTTGAGCCACTGCAGTATGCATTTCTATTTTTAAGCAAAGATCTTGGTCTTTCTTTTTG GACATTGTAGAAATAACATGAACTTGTTTTTTGTTTGTTTTTGTTTTGTTTTGTTTTAAGCTCCTGATCTTTGTTGGTTATGTTGCAAAA GATTGTATCAGGAGAAGCCTCAGCATGGACATTGGCATCCTGACATAACCCCCATTAATTTAGTATTCTTTCTGAAACTCAAATGGATTC TCAAGTCCAAGAGACTATGGAATAAAATCATTGTTTGTCTGTGTTAAGTTTTATCTCTGTTATTGCCTGAAGACTTTTGGTAACAATAAT >13523_13523_3_CCAR1-PAWR_CCAR1_chr10_70546400_ENST00000543719_PAWR_chr12_79988215_ENST00000328827_length(amino acids)=930AA_BP=912 MAQFGGQKNPPWATQFTATAVSQPAALGVQQPSLLGASPTIYTQQTALAAAGLTTQTPANYQLTQTAALQQQAAAAAAALQQLQQPQQTL LTQPAVALPTSLSLSTPQPTAQITVSYPTPRSSQQQTQPQKQRVFTGVVTKLHDTFGFVDEDVFFQLSAVKGKTPQVGDRVLVEATYNPN MPFKWNAQRIQTLPNQNQSQTQPLLKTPPAVLQPIAPQTTFGVQTQPQPQSLLQAQISAASITPLLQTQPQPLLQQPQQKAGLLQPPVRI VSQPQPARRLDPPSRFSGRNDRGDQVPNRKDDRSRERERERRRSRERSPQRKRSRERSPRRERERSPRRVRRVVPRYTVQFSKFSLDCPS CDMMELRRRYQNLYIPSDFFDAQFTWVDAFPLSRPFQLGNYCNFYVMHREVESLEKNMAILDPPDADHLYSAKVMLMASPSMEDLYHKSC ALAEDPQELRDGFQHPARLVKFLVGMKGKDEAMAIGGHWSPSLDGPDPEKDPSVLIKTAIRCCKALTGIDLSVCTQWYRFAEIRYHRPEE THKGRTVPAHVETVVLFFPDVWHCLPTRSEWETLSRGYKQQLVEKLQGERKEADGEQDEEEKDDGEAKEISTPTHWSKLDPKTMKVNDLR KELESRALSSKGLKSQLIARLTKQLKVEEQKEEQKELEKSEKEEDEDDDRKSEDDKEEEERKRQEEIERQRRERRYILPDEPAIIVHPNW AAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVSLFAELFNEMLQRDFGVRIYKSLLSLPEKEDKKEKDKKSKKDERKDKKEERDDETDEP KPKRRKSGDDKDKKEDRDERKKEDKRKDDSKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDKRDINRYCKERPSKDKFGRN -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for CCAR1-PAWR |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| Hgene | CCAR1 | chr10:70546400 | chr12:79988215 | ENST00000265872 | + | 1 | 25 | 1_249 | 0 | 1151.0 | AR |
| Hgene | CCAR1 | chr10:70546400 | chr12:79988215 | ENST00000535016 | + | 1 | 24 | 1_249 | 0 | 1136.0 | AR |
| Hgene | CCAR1 | chr10:70546400 | chr12:79988215 | ENST00000543719 | + | 1 | 24 | 1_249 | 0 | 1136.0 | AR |
| Hgene | CCAR1 | chr10:70546400 | chr12:79988215 | ENST00000265872 | + | 1 | 25 | 643_1150 | 0 | 1151.0 | GATA1 |
| Hgene | CCAR1 | chr10:70546400 | chr12:79988215 | ENST00000535016 | + | 1 | 24 | 643_1150 | 0 | 1136.0 | GATA1 |
| Hgene | CCAR1 | chr10:70546400 | chr12:79988215 | ENST00000543719 | + | 1 | 24 | 643_1150 | 0 | 1136.0 | GATA1 |
| Hgene | CCAR1 | chr10:70546400 | chr12:79988215 | ENST00000265872 | + | 1 | 25 | 203_660 | 0 | 1151.0 | GATA2 |
| Hgene | CCAR1 | chr10:70546400 | chr12:79988215 | ENST00000535016 | + | 1 | 24 | 203_660 | 0 | 1136.0 | GATA2 |
| Hgene | CCAR1 | chr10:70546400 | chr12:79988215 | ENST00000543719 | + | 1 | 24 | 203_660 | 0 | 1136.0 | GATA2 |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for CCAR1-PAWR |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for CCAR1-PAWR |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | C0036341 | Schizophrenia | 2 | PSYGENET | |
| Tgene | C0041696 | Unipolar Depression | 2 | PSYGENET | |
| Tgene | C1269683 | Major Depressive Disorder | 2 | PSYGENET | |
| Tgene | C0001418 | Adenocarcinoma | 1 | CTD_human | |
| Tgene | C0014170 | Endometrial Neoplasms | 1 | CTD_human | |
| Tgene | C0033578 | Prostatic Neoplasms | 1 | CTD_human | |
| Tgene | C0033975 | Psychotic Disorders | 1 | PSYGENET | |
| Tgene | C0205641 | Adenocarcinoma, Basal Cell | 1 | CTD_human | |
| Tgene | C0205642 | Adenocarcinoma, Oxyphilic | 1 | CTD_human | |
| Tgene | C0205643 | Carcinoma, Cribriform | 1 | CTD_human | |
| Tgene | C0205644 | Carcinoma, Granular Cell | 1 | CTD_human | |
| Tgene | C0205645 | Adenocarcinoma, Tubular | 1 | CTD_human | |
| Tgene | C0376358 | Malignant neoplasm of prostate | 1 | CTD_human | |
| Tgene | C0476089 | Endometrial Carcinoma | 1 | CTD_human |
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