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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:BDP1-MCCC2 (FusionGDB2 ID:HG55814TG64087)

Fusion Gene Summary for BDP1-MCCC2

check button Fusion gene summary
Fusion gene informationFusion gene name: BDP1-MCCC2
Fusion gene ID: hg55814tg64087
HgeneTgene
Gene symbol

BDP1

MCCC2

Gene ID

55814

64087

Gene nameB double prime 1, subunit of RNA polymerase III transcription initiation factor IIIBmethylcrotonoyl-CoA carboxylase 2
SynonymsDFNB112|HSA238520|TAF3B1|TFC5|TFIIIB''|TFIIIB150|TFIIIB90|TFNRMCCB
Cytomap('BDP1')('MCCC2')

5q13.2

5q13.2

Type of geneprotein-codingprotein-coding
Descriptiontranscription factor TFIIIB component B'' homologRNA polymerase III transcription initiation factor B''TATA box binding protein (TBP)-associated factor, RNA polymerase III, GTF3B subunit 1transcription factor IIIB 150transcription factor-like nuclear methylcrotonoyl-CoA carboxylase beta chain, mitochondrial3-methylcrotonyl-CoA carboxylase 23-methylcrotonyl-CoA carboxylase non-biotin-containing subunit3-methylcrotonyl-CoA:carbon dioxide ligase subunit betaMCCase subunit betabiotin carboxylasemeth
Modification date2020031320200322
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000358731, ENST00000380675, 
Fusion gene scores* DoF score8 X 8 X 5=3205 X 7 X 3=105
# samples 96
** MAII scorelog2(9/320*10)=-1.83007499855769
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(6/105*10)=-0.807354922057604
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: BDP1 [Title/Abstract] AND MCCC2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointBDP1(70766316)-MCCC2(70927948), # samples:1
BDP1(70766316)-MCCC2(70922467), # samples:1
Anticipated loss of major functional domain due to fusion event.BDP1-MCCC2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
BDP1-MCCC2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
BDP1-MCCC2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
BDP1-MCCC2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across BDP1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across MCCC2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-A7-A26I-01ABDP1chr5

70766316

+MCCC2chr5

70922467

+
ChimerDB4BRCATCGA-A7-A26I-01ABDP1chr5

70766316

+MCCC2chr5

70927948

+


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Fusion Gene ORF analysis for BDP1-MCCC2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000358731ENST00000510895BDP1chr5

70766316

+MCCC2chr5

70922467

+
5CDS-3UTRENST00000358731ENST00000510895BDP1chr5

70766316

+MCCC2chr5

70927948

+
5CDS-intronENST00000358731ENST00000323375BDP1chr5

70766316

+MCCC2chr5

70922467

+
5UTR-3CDSENST00000380675ENST00000323375BDP1chr5

70766316

+MCCC2chr5

70927948

+
5UTR-3CDSENST00000380675ENST00000340941BDP1chr5

70766316

+MCCC2chr5

70922467

+
5UTR-3CDSENST00000380675ENST00000340941BDP1chr5

70766316

+MCCC2chr5

70927948

+
5UTR-3CDSENST00000380675ENST00000509358BDP1chr5

70766316

+MCCC2chr5

70922467

+
5UTR-3CDSENST00000380675ENST00000509358BDP1chr5

70766316

+MCCC2chr5

70927948

+
5UTR-3UTRENST00000380675ENST00000510895BDP1chr5

70766316

+MCCC2chr5

70922467

+
5UTR-3UTRENST00000380675ENST00000510895BDP1chr5

70766316

+MCCC2chr5

70927948

+
5UTR-intronENST00000380675ENST00000323375BDP1chr5

70766316

+MCCC2chr5

70922467

+
In-frameENST00000358731ENST00000323375BDP1chr5

70766316

+MCCC2chr5

70927948

+
In-frameENST00000358731ENST00000340941BDP1chr5

70766316

+MCCC2chr5

70922467

+
In-frameENST00000358731ENST00000340941BDP1chr5

70766316

+MCCC2chr5

70927948

+
In-frameENST00000358731ENST00000509358BDP1chr5

70766316

+MCCC2chr5

70922467

+
In-frameENST00000358731ENST00000509358BDP1chr5

70766316

+MCCC2chr5

70927948

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)
BP loci
(transcript)
Predicted start
(transcript)
Predicted stop
(transcript)
Seq length
(amino acids)
ENST00000358731BDP1chr570766316+ENST00000340941MCCC2chr570927948+407512772632230655
ENST00000358731BDP1chr570766316+ENST00000509358MCCC2chr570927948+165712772631630455
ENST00000358731BDP1chr570766316+ENST00000323375MCCC2chr570927948+258312772632230655
ENST00000358731BDP1chr570766316+ENST00000340941MCCC2chr570922467+418912772632344693
ENST00000358731BDP1chr570766316+ENST00000509358MCCC2chr570922467+177112772631744493

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000358731ENST00000340941BDP1chr570766316+MCCC2chr570927948+0.000212580.9997874
ENST00000358731ENST00000509358BDP1chr570766316+MCCC2chr570927948+0.000747030.999253
ENST00000358731ENST00000323375BDP1chr570766316+MCCC2chr570927948+0.0002584210.9997416
ENST00000358731ENST00000340941BDP1chr570766316+MCCC2chr570922467+0.0002524750.9997476
ENST00000358731ENST00000509358BDP1chr570766316+MCCC2chr570922467+0.0006883590.9993117

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Fusion Genomic Features for BDP1-MCCC2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
BDP1chr570766316+MCCC2chr570927947+1.85E-081
BDP1chr570766316+MCCC2chr570922466+2.47E-081
BDP1chr570766316+MCCC2chr570927947+1.85E-081
BDP1chr570766316+MCCC2chr570922466+2.47E-081

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for BDP1-MCCC2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr5:70766316/chr5:70927948)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneBDP1chr5:70766316chr5:70922467ENST00000358731+739144_1773382625.0Coiled coilOntology_term=ECO:0000255
HgeneBDP1chr5:70766316chr5:70927948ENST00000358731+739144_1773382625.0Coiled coilOntology_term=ECO:0000255
HgeneBDP1chr5:70766316chr5:70922467ENST00000358731+73984_1193382625.0Compositional biasNote=Ser-rich
HgeneBDP1chr5:70766316chr5:70927948ENST00000358731+73984_1193382625.0Compositional biasNote=Ser-rich
TgeneMCCC2chr5:70766316chr5:70922467ENST00000323375016309_5550526.0DomainCoA carboxyltransferase C-terminal
TgeneMCCC2chr5:70766316chr5:70922467ENST0000032337501649_3060526.0DomainCoA carboxyltransferase N-terminal
TgeneMCCC2chr5:70766316chr5:70922467ENST00000340941517309_555208564.0DomainCoA carboxyltransferase C-terminal
TgeneMCCC2chr5:70766316chr5:70927948ENST00000323375516309_555208526.0DomainCoA carboxyltransferase C-terminal
TgeneMCCC2chr5:70766316chr5:70927948ENST00000340941617309_555246564.0DomainCoA carboxyltransferase C-terminal
TgeneMCCC2chr5:70766316chr5:70922467ENST00000323375016343_3720526.0RegionAcyl-CoA binding
TgeneMCCC2chr5:70766316chr5:70922467ENST0000032337501649_5550526.0RegionCarboxyltransferase
TgeneMCCC2chr5:70766316chr5:70922467ENST00000340941517343_372208564.0RegionAcyl-CoA binding
TgeneMCCC2chr5:70766316chr5:70927948ENST00000323375516343_372208526.0RegionAcyl-CoA binding
TgeneMCCC2chr5:70766316chr5:70927948ENST00000340941617343_372246564.0RegionAcyl-CoA binding

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneBDP1chr5:70766316chr5:70922467ENST00000358731+7391078_11033382625.0Coiled coilOntology_term=ECO:0000255
HgeneBDP1chr5:70766316chr5:70922467ENST00000358731+7391223_12843382625.0Coiled coilOntology_term=ECO:0000255
HgeneBDP1chr5:70766316chr5:70922467ENST00000380675+7381078_110301360.6666666666667Coiled coilOntology_term=ECO:0000255
HgeneBDP1chr5:70766316chr5:70922467ENST00000380675+7381223_128401360.6666666666667Coiled coilOntology_term=ECO:0000255
HgeneBDP1chr5:70766316chr5:70922467ENST00000380675+738144_17701360.6666666666667Coiled coilOntology_term=ECO:0000255
HgeneBDP1chr5:70766316chr5:70927948ENST00000358731+7391078_11033382625.0Coiled coilOntology_term=ECO:0000255
HgeneBDP1chr5:70766316chr5:70927948ENST00000358731+7391223_12843382625.0Coiled coilOntology_term=ECO:0000255
HgeneBDP1chr5:70766316chr5:70927948ENST00000380675+7381078_110301360.6666666666667Coiled coilOntology_term=ECO:0000255
HgeneBDP1chr5:70766316chr5:70927948ENST00000380675+7381223_128401360.6666666666667Coiled coilOntology_term=ECO:0000255
HgeneBDP1chr5:70766316chr5:70927948ENST00000380675+738144_17701360.6666666666667Coiled coilOntology_term=ECO:0000255
HgeneBDP1chr5:70766316chr5:70922467ENST00000380675+73884_11901360.6666666666667Compositional biasNote=Ser-rich
HgeneBDP1chr5:70766316chr5:70927948ENST00000380675+73884_11901360.6666666666667Compositional biasNote=Ser-rich
HgeneBDP1chr5:70766316chr5:70922467ENST00000358731+739295_3453382625.0DomainNote=Myb-like
HgeneBDP1chr5:70766316chr5:70922467ENST00000380675+738295_34501360.6666666666667DomainNote=Myb-like
HgeneBDP1chr5:70766316chr5:70927948ENST00000358731+739295_3453382625.0DomainNote=Myb-like
HgeneBDP1chr5:70766316chr5:70927948ENST00000380675+738295_34501360.6666666666667DomainNote=Myb-like
HgeneBDP1chr5:70766316chr5:70922467ENST00000358731+739355_4703382625.0RegionNote=Required for phosphorylation by CSNK2A1
HgeneBDP1chr5:70766316chr5:70922467ENST00000358731+739823_13273382625.0RegionNote=9 X 55 AA repeats of G-R-R-X-I-S-P-X-E-N-G-X-E-E-V-K-P-X-X-E-M-E-T-D-L-K-X-T-G-R-E-X-X-X-R-E-K-T-X-E-X-X-D-A-X-E-E-I-D-X-D-L-E-E-T
HgeneBDP1chr5:70766316chr5:70922467ENST00000380675+738355_47001360.6666666666667RegionNote=Required for phosphorylation by CSNK2A1
HgeneBDP1chr5:70766316chr5:70922467ENST00000380675+738823_132701360.6666666666667RegionNote=9 X 55 AA repeats of G-R-R-X-I-S-P-X-E-N-G-X-E-E-V-K-P-X-X-E-M-E-T-D-L-K-X-T-G-R-E-X-X-X-R-E-K-T-X-E-X-X-D-A-X-E-E-I-D-X-D-L-E-E-T
HgeneBDP1chr5:70766316chr5:70927948ENST00000358731+739355_4703382625.0RegionNote=Required for phosphorylation by CSNK2A1
HgeneBDP1chr5:70766316chr5:70927948ENST00000358731+739823_13273382625.0RegionNote=9 X 55 AA repeats of G-R-R-X-I-S-P-X-E-N-G-X-E-E-V-K-P-X-X-E-M-E-T-D-L-K-X-T-G-R-E-X-X-X-R-E-K-T-X-E-X-X-D-A-X-E-E-I-D-X-D-L-E-E-T
HgeneBDP1chr5:70766316chr5:70927948ENST00000380675+738355_47001360.6666666666667RegionNote=Required for phosphorylation by CSNK2A1
HgeneBDP1chr5:70766316chr5:70927948ENST00000380675+738823_132701360.6666666666667RegionNote=9 X 55 AA repeats of G-R-R-X-I-S-P-X-E-N-G-X-E-E-V-K-P-X-X-E-M-E-T-D-L-K-X-T-G-R-E-X-X-X-R-E-K-T-X-E-X-X-D-A-X-E-E-I-D-X-D-L-E-E-T
HgeneBDP1chr5:70766316chr5:70922467ENST00000358731+7391041_10943382625.0RepeatNote=5
HgeneBDP1chr5:70766316chr5:70922467ENST00000358731+7391095_11483382625.0RepeatNote=6
HgeneBDP1chr5:70766316chr5:70922467ENST00000358731+7391149_12033382625.0RepeatNote=7
HgeneBDP1chr5:70766316chr5:70922467ENST00000358731+7391204_12573382625.0RepeatNote=8%3B approximate
HgeneBDP1chr5:70766316chr5:70922467ENST00000358731+7391258_13273382625.0RepeatNote=9%3B approximate
HgeneBDP1chr5:70766316chr5:70922467ENST00000358731+739823_8773382625.0RepeatNote=1%3B approximate
HgeneBDP1chr5:70766316chr5:70922467ENST00000358731+739878_9323382625.0RepeatNote=2
HgeneBDP1chr5:70766316chr5:70922467ENST00000358731+739933_9873382625.0RepeatNote=3
HgeneBDP1chr5:70766316chr5:70922467ENST00000358731+739988_10403382625.0RepeatNote=4
HgeneBDP1chr5:70766316chr5:70922467ENST00000380675+7381041_109401360.6666666666667RepeatNote=5
HgeneBDP1chr5:70766316chr5:70922467ENST00000380675+7381095_114801360.6666666666667RepeatNote=6
HgeneBDP1chr5:70766316chr5:70922467ENST00000380675+7381149_120301360.6666666666667RepeatNote=7
HgeneBDP1chr5:70766316chr5:70922467ENST00000380675+7381204_125701360.6666666666667RepeatNote=8%3B approximate
HgeneBDP1chr5:70766316chr5:70922467ENST00000380675+7381258_132701360.6666666666667RepeatNote=9%3B approximate
HgeneBDP1chr5:70766316chr5:70922467ENST00000380675+738823_87701360.6666666666667RepeatNote=1%3B approximate
HgeneBDP1chr5:70766316chr5:70922467ENST00000380675+738878_93201360.6666666666667RepeatNote=2
HgeneBDP1chr5:70766316chr5:70922467ENST00000380675+738933_98701360.6666666666667RepeatNote=3
HgeneBDP1chr5:70766316chr5:70922467ENST00000380675+738988_104001360.6666666666667RepeatNote=4
HgeneBDP1chr5:70766316chr5:70927948ENST00000358731+7391041_10943382625.0RepeatNote=5
HgeneBDP1chr5:70766316chr5:70927948ENST00000358731+7391095_11483382625.0RepeatNote=6
HgeneBDP1chr5:70766316chr5:70927948ENST00000358731+7391149_12033382625.0RepeatNote=7
HgeneBDP1chr5:70766316chr5:70927948ENST00000358731+7391204_12573382625.0RepeatNote=8%3B approximate
HgeneBDP1chr5:70766316chr5:70927948ENST00000358731+7391258_13273382625.0RepeatNote=9%3B approximate
HgeneBDP1chr5:70766316chr5:70927948ENST00000358731+739823_8773382625.0RepeatNote=1%3B approximate
HgeneBDP1chr5:70766316chr5:70927948ENST00000358731+739878_9323382625.0RepeatNote=2
HgeneBDP1chr5:70766316chr5:70927948ENST00000358731+739933_9873382625.0RepeatNote=3
HgeneBDP1chr5:70766316chr5:70927948ENST00000358731+739988_10403382625.0RepeatNote=4
HgeneBDP1chr5:70766316chr5:70927948ENST00000380675+7381041_109401360.6666666666667RepeatNote=5
HgeneBDP1chr5:70766316chr5:70927948ENST00000380675+7381095_114801360.6666666666667RepeatNote=6
HgeneBDP1chr5:70766316chr5:70927948ENST00000380675+7381149_120301360.6666666666667RepeatNote=7
HgeneBDP1chr5:70766316chr5:70927948ENST00000380675+7381204_125701360.6666666666667RepeatNote=8%3B approximate
HgeneBDP1chr5:70766316chr5:70927948ENST00000380675+7381258_132701360.6666666666667RepeatNote=9%3B approximate
HgeneBDP1chr5:70766316chr5:70927948ENST00000380675+738823_87701360.6666666666667RepeatNote=1%3B approximate
HgeneBDP1chr5:70766316chr5:70927948ENST00000380675+738878_93201360.6666666666667RepeatNote=2
HgeneBDP1chr5:70766316chr5:70927948ENST00000380675+738933_98701360.6666666666667RepeatNote=3
HgeneBDP1chr5:70766316chr5:70927948ENST00000380675+738988_104001360.6666666666667RepeatNote=4
TgeneMCCC2chr5:70766316chr5:70922467ENST0000034094151749_306208564.0DomainCoA carboxyltransferase N-terminal
TgeneMCCC2chr5:70766316chr5:70927948ENST0000032337551649_306208526.0DomainCoA carboxyltransferase N-terminal
TgeneMCCC2chr5:70766316chr5:70927948ENST0000034094161749_306246564.0DomainCoA carboxyltransferase N-terminal
TgeneMCCC2chr5:70766316chr5:70922467ENST0000034094151749_555208564.0RegionCarboxyltransferase
TgeneMCCC2chr5:70766316chr5:70927948ENST0000032337551649_555208526.0RegionCarboxyltransferase
TgeneMCCC2chr5:70766316chr5:70927948ENST0000034094161749_555246564.0RegionCarboxyltransferase


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Fusion Gene Sequence for BDP1-MCCC2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>9570_9570_1_BDP1-MCCC2_BDP1_chr5_70766316_ENST00000358731_MCCC2_chr5_70922467_ENST00000340941_length(transcript)=4189nt_BP=1277nt
AGTTGCGGCGTCCTGTGAGCGCGGGGATGCTGGGAGGAGGGTGAAATTTAGCCATCGGTGTGTGGCAGGGTCATGAAAAAGCGGCGGCGG
CGGGAGAGAGGAGGAGGCGGCGGCGGGGCAGTGAAACTACGGTAGCTGCCCCCTGAGCTGGTGGTGTGGCTTTGTGGGGAGGGCGTAGTT
CCTAATCCCCTTTCCGGGCAGCCGCCGGGGCTCGGGGCTGTGAGCGGCCGTGAGGCTGCCTCCCCGGGCCCCCTGCCTCCGCCATGTTCC
GCAGGGCACGCCTTAGCGTGAAGCCGAATGTCAGGCCTGGTGTAGGCGCCAGGGGCTCCACAGCTTCCAATCCCCAGCGTGGACGGGAGT
CTCCCAGGCCGCCGGATCCTGCCACGGACTCTGCTTCCAAGCCCGCGGAGCCCACAGATGTGCCCACAGTCGATTTCGGTGGAGCGGAGC
CCCAAGAAAAGGCTCCTAGGAGCAGTACTGAAAAGACTGGTGGTGACAATGATGTTGAAGAATCCAGTAGATCTTCCTCTACTGTTTCAC
AGAGAAGAAAGCGAATATCAAGTACTTCTAGCCTGGTTAAGTCTAGTGTCAGTGTTCCTTCAGAATCTCATCCCTTATCTACAATTAATC
AAGAGGCTCCACAGCCAACTGCCACTTCAACAAAAGAGAAACAGCCATGCTCAGACAGATACCGAATATACAAAGCCCAGAAACTGAGGG
AAATGTTAAAAGAAGAATTGAGAAAAGAGAAGAAACAATGGAAAAACAAATATGCTATAAATGAAAGTCAGAGGCCACCAGATCGTTCAA
AAATGACTATGAGAGACTTCATATATTATCTACCAGATAATAATCCAATGACTTCTTCACTGGAACAAGAAAAGAAAACTGAAAAGCCAT
CGACTCCAGTCCAGACAAGAGAGCAAGAAGGTAAGAGTACTCCTAATGCTGAAGATAATGAAATGGAAGAAGAGACAGATGATGGGCCAT
TACTGGTTCCTCGAGTAAAAGTGGCAGAAGATGGTTCCATTATTTTGGATGAAGAAAGTTTAACTGTAGAAGTTTTAAGAACAAAAGGCC
CTTGTGTTGTTGAAGAAAATGACCCCATATTTGAGCGCGGTTCTACAACTACATACTCCAGCTTTAGGAAAAACTATTACTCTAAACCAT
GGTCAAATAAAGAAACAGATATGTTTTTTTTAGCCATCAGCATGGTAGGAACTGACTTTTCTATGATCGGACAACTTTTTCCTCACAGAG
CAAGGATAGAAATTAAGATCGCAGTGGTCATGGGCTCCTGCACCGCAGGAGGAGCCTATGTGCCTGCCATGGCTGATGAAAACATCATTG
TACGCAAGCAGGGTACCATTTTCTTGGCAGGACCCCCCTTGGTTAAAGCGGCAACTGGGGAAGAAGTATCTGCTGAGGATCTTGGAGGTG
CTGATCTTCATTGCAGAAAGTCTGGAGTAAGTGACCACTGGGCTTTGGATGATCATCATGCCCTTCACTTAACTAGGAAGGTTGTGAGGA
ATCTAAATTATCAGAAGAAATTGGATGTCACCATTGAACCTTCTGAAGAGCCTTTATTTCCTGCTGATGAATTGTATGGAATAGTTGGTG
CTAACCTTAAGAGGAGCTTTGATGTCCGAGAGGTCATTGCTAGAATCGTGGATGGAAGCAGATTCACTGAGTTCAAAGCCTTTTATGGAG
ACACATTAGTTACAGGATTTGCTCGAATATTTGGGTACCCAGTAGGTATCGTTGGAAACAACGGAGTTCTCTTTTCTGAATCTGCAAAAA
AGGGTACTCACTTTGTCCAGTTATGCTGCCAAAGAAATATTCCTCTGCTGTTCCTTCAAAACATTACTGGATTTATGGTTGGTAGAGAGT
ATGAAGCTGAAGGAATTGCCAAGGATGGTGCCAAGATGGTGGCCGCTGTGGCCTGTGCCCAAGTGCCTAAGATAACCCTCATCATTGGGG
GCTCCTATGGAGCCGGAAACTATGGGATGTGTGGCAGAGCATATAGCCCAAGATTTCTCTACATTTGGCCAAATGCTCGTATCTCAGTGA
TGGGAGGAGAGCAGGCAGCCAATGTGTTGGCCACGATAACAAAGGACCAAAGAGCCCGGGAAGGAAAGCAGTTCTCCAGTGCTGATGAAG
CGGCTTTAAAAGAGCCCATCATTAAGAAGTTTGAAGAGGAAGGAAACCCTTACTATTCCAGCGCAAGGGTATGGGATGATGGGATCATTG
ATCCAGCAGACACCAGACTGGTCTTGGGTCTCAGTTTTAGTGCAGCCCTCAACGCACCAATAGAGAAGACTGACTTCGGTATCTTCAGGA
TGTAACTGGAATAAAGGATGTTTTCTGTTGGACATGTACTGAAAATTAACACATGTAGTAGCCTTAAAATTTTAGACTTCTCGAACATGA
GGCTGTTACAGTAATTTTTTTAACACTGTGCATTGTACTTTTCTACCTTAAAAAAATCAGTGAGGATATTTATTTAATGAACATCAATTC
CTTTTAAATTTTCTTAGAGAAATTTCTCTGTGGCTCAGTTTTACCACCCATAAAGCGGAGACAGTAATTTACGGTTATCCTTTCTGACCC
ACAAAGTATGAAAAGTTCTGTAATCTGTAAACTCAGTTCTGTAATCTGTATTATTGAGATGATTAATATAAAGTTGTATTTTCACTGAAA
TGATTGTTTTGCTGGTTATGCTTGGTGATATTTTAGCGGGCTTATTTTTGAAAGGCATCTGTTACTTCAGTGGCATAAAGTGCCCTCACA
CTGCTGTGCAGCCATCACCACCATTCATCTCCAGAATTTGTTCTCAGTCCCAAACTGAAACTATACCATTCAAACAACAGCGCTCCCCAT
TTCCCCCTCCCCCGAGCCCATGACATCTCCTTATTATTATTTTTTTTTTGAGACAGGGTGTTTCTCTGTTGCCCAGGCTGGAGTGCGGTG
GTGTGATCTCGGCTCACTGCAGCTTCCACCTCCCGGGTTCAAGCGATTCTTGTGCCTCAGCCTCCCAAGCAGCTGGGACTATAGGCACGC
ACCACCACACCCAGCTAAGTTCTGTATTTTTAGCAGAGACGGGATTTCACTAGGTTGCCCAGGCTGGTCTCAAACTACTGACCTCAAGTG
ATCCACCCGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACCGCGCCTGACCACATCTCCTTATTCTTAAATGTATGTGTT
TCTCATGGTTTGATTTATTCTTGCTGGGCCATTTCAGCCCCTGTCATGGCTTCACTCGCCATCTAAATGCAGATGATTACTGCCTTGACG
GTTCTTAACCCAGCTCTCCCCTGAGCTGCAGGCCTGCATATCCAGTAGGTCTACTGGACATCTGTACTGGTTGTTGTGGAGGAACCTCTG
GCTTGCTCATTAAGTCCTACTGATTTTCACTATCCCCTGAATTTCCCCACTTATTTTTGTCTTTCACTATCGCAGGCCTTAGAAGAGGTC
TACCTGCCTCCAGTCTTACCTAGTCCAGTCTACCCCCTGGAGTTAGAATGGCCATCCTGAAGTGAAAAGTAATGTCAGATTACTCCCTTC
AGTGATTTCTTGTAGAAGTGCCAATCCCTGAATGCCACCAAGATCTTAATCTTCACATCTTTAATCTTATCTCTTTGACTCCTCTTTACA
CCGGAGAACGGCTCCAGCTGTTCTAGCTCTCTTTCAGTTCTTTGAACCTTCCCACCTTAGGGTCTATAAGGTTCCCTCTGCCCAAATTGT
TCTACTCTCCCTTCTTCTTCAACACATCCTTCAGTTTAAGCACTTGCTTCTCTCAGTTTAAACTCCACTTCCTTAGGGATGTCTCTGTGA
CCTCCCTGTGCTGGATTAGCTTCCCTACTCTATGCTCTTGTAAAACACTATCTACTTCCTTTGTCATAAACTCATCATTTTCCTATAAAC
ATTAATATTGTCCTCCTGCTAGAATGTAAGCTCCGTGAGAGCAAGGATCCTCCTGTTTACCCTGTACCTCCAATGTCTGGCACTTGTAGG
TGCTCAAATATTCGTTGAATGAATGAAAAATCCATATTGTAATTGATGTCCTCTGGCCACATAGTTTTAAAATTAGGTGATTGATTATAT

>9570_9570_1_BDP1-MCCC2_BDP1_chr5_70766316_ENST00000358731_MCCC2_chr5_70922467_ENST00000340941_length(amino acids)=693AA_BP=0
MFRRARLSVKPNVRPGVGARGSTASNPQRGRESPRPPDPATDSASKPAEPTDVPTVDFGGAEPQEKAPRSSTEKTGGDNDVEESSRSSST
VSQRRKRISSTSSLVKSSVSVPSESHPLSTINQEAPQPTATSTKEKQPCSDRYRIYKAQKLREMLKEELRKEKKQWKNKYAINESQRPPD
RSKMTMRDFIYYLPDNNPMTSSLEQEKKTEKPSTPVQTREQEGKSTPNAEDNEMEEETDDGPLLVPRVKVAEDGSIILDEESLTVEVLRT
KGPCVVEENDPIFERGSTTTYSSFRKNYYSKPWSNKETDMFFLAISMVGTDFSMIGQLFPHRARIEIKIAVVMGSCTAGGAYVPAMADEN
IIVRKQGTIFLAGPPLVKAATGEEVSAEDLGGADLHCRKSGVSDHWALDDHHALHLTRKVVRNLNYQKKLDVTIEPSEEPLFPADELYGI
VGANLKRSFDVREVIARIVDGSRFTEFKAFYGDTLVTGFARIFGYPVGIVGNNGVLFSESAKKGTHFVQLCCQRNIPLLFLQNITGFMVG
REYEAEGIAKDGAKMVAAVACAQVPKITLIIGGSYGAGNYGMCGRAYSPRFLYIWPNARISVMGGEQAANVLATITKDQRAREGKQFSSA

--------------------------------------------------------------
>9570_9570_2_BDP1-MCCC2_BDP1_chr5_70766316_ENST00000358731_MCCC2_chr5_70922467_ENST00000509358_length(transcript)=1771nt_BP=1277nt
AGTTGCGGCGTCCTGTGAGCGCGGGGATGCTGGGAGGAGGGTGAAATTTAGCCATCGGTGTGTGGCAGGGTCATGAAAAAGCGGCGGCGG
CGGGAGAGAGGAGGAGGCGGCGGCGGGGCAGTGAAACTACGGTAGCTGCCCCCTGAGCTGGTGGTGTGGCTTTGTGGGGAGGGCGTAGTT
CCTAATCCCCTTTCCGGGCAGCCGCCGGGGCTCGGGGCTGTGAGCGGCCGTGAGGCTGCCTCCCCGGGCCCCCTGCCTCCGCCATGTTCC
GCAGGGCACGCCTTAGCGTGAAGCCGAATGTCAGGCCTGGTGTAGGCGCCAGGGGCTCCACAGCTTCCAATCCCCAGCGTGGACGGGAGT
CTCCCAGGCCGCCGGATCCTGCCACGGACTCTGCTTCCAAGCCCGCGGAGCCCACAGATGTGCCCACAGTCGATTTCGGTGGAGCGGAGC
CCCAAGAAAAGGCTCCTAGGAGCAGTACTGAAAAGACTGGTGGTGACAATGATGTTGAAGAATCCAGTAGATCTTCCTCTACTGTTTCAC
AGAGAAGAAAGCGAATATCAAGTACTTCTAGCCTGGTTAAGTCTAGTGTCAGTGTTCCTTCAGAATCTCATCCCTTATCTACAATTAATC
AAGAGGCTCCACAGCCAACTGCCACTTCAACAAAAGAGAAACAGCCATGCTCAGACAGATACCGAATATACAAAGCCCAGAAACTGAGGG
AAATGTTAAAAGAAGAATTGAGAAAAGAGAAGAAACAATGGAAAAACAAATATGCTATAAATGAAAGTCAGAGGCCACCAGATCGTTCAA
AAATGACTATGAGAGACTTCATATATTATCTACCAGATAATAATCCAATGACTTCTTCACTGGAACAAGAAAAGAAAACTGAAAAGCCAT
CGACTCCAGTCCAGACAAGAGAGCAAGAAGGTAAGAGTACTCCTAATGCTGAAGATAATGAAATGGAAGAAGAGACAGATGATGGGCCAT
TACTGGTTCCTCGAGTAAAAGTGGCAGAAGATGGTTCCATTATTTTGGATGAAGAAAGTTTAACTGTAGAAGTTTTAAGAACAAAAGGCC
CTTGTGTTGTTGAAGAAAATGACCCCATATTTGAGCGCGGTTCTACAACTACATACTCCAGCTTTAGGAAAAACTATTACTCTAAACCAT
GGTCAAATAAAGAAACAGATATGTTTTTTTTAGCCATCAGCATGGTAGGAACTGACTTTTCTATGATCGGACAACTTTTTCCTCACAGAG
CAAGGATAGAAATTAAGATCGCAGTGGTCATGGGCTCCTGCACCGCAGGAGGAGCCTATGTGCCTGCCATGGCTGATGAAAACATCATTG
TACGCAAGCAGGGTACCATTTTCTTGGCAGGACCCCCCTTGGTTAAAGCGGCAACTGGGGAAGAAGTATCTGCTGAGGATCTTGGAGGTG
CTGATCTTCATTGCAGAAAGTCTGGAGTAAGTGACCACTGGGCTTTGGATGATCATCATGCCCTTCACTTAACTAGGAAGGTTGTGAGGA
ATCTAAATTATCAGAAGAAATTGGATGTCACCATTGAACCTTCTGAAGAGCCTTTATTTCCTGCTGATGAATTGTATGGAATAGTTGGTG
CTAACCTTAAGAGGAGCTTTGATGTCCGAGAGGTCATTGCTAGAATCGTGGATGGAAGCAGATTCACTGAGTTCAAAGCCTTTTATGGAG

>9570_9570_2_BDP1-MCCC2_BDP1_chr5_70766316_ENST00000358731_MCCC2_chr5_70922467_ENST00000509358_length(amino acids)=493AA_BP=0
MFRRARLSVKPNVRPGVGARGSTASNPQRGRESPRPPDPATDSASKPAEPTDVPTVDFGGAEPQEKAPRSSTEKTGGDNDVEESSRSSST
VSQRRKRISSTSSLVKSSVSVPSESHPLSTINQEAPQPTATSTKEKQPCSDRYRIYKAQKLREMLKEELRKEKKQWKNKYAINESQRPPD
RSKMTMRDFIYYLPDNNPMTSSLEQEKKTEKPSTPVQTREQEGKSTPNAEDNEMEEETDDGPLLVPRVKVAEDGSIILDEESLTVEVLRT
KGPCVVEENDPIFERGSTTTYSSFRKNYYSKPWSNKETDMFFLAISMVGTDFSMIGQLFPHRARIEIKIAVVMGSCTAGGAYVPAMADEN
IIVRKQGTIFLAGPPLVKAATGEEVSAEDLGGADLHCRKSGVSDHWALDDHHALHLTRKVVRNLNYQKKLDVTIEPSEEPLFPADELYGI

--------------------------------------------------------------
>9570_9570_3_BDP1-MCCC2_BDP1_chr5_70766316_ENST00000358731_MCCC2_chr5_70927948_ENST00000323375_length(transcript)=2583nt_BP=1277nt
AGTTGCGGCGTCCTGTGAGCGCGGGGATGCTGGGAGGAGGGTGAAATTTAGCCATCGGTGTGTGGCAGGGTCATGAAAAAGCGGCGGCGG
CGGGAGAGAGGAGGAGGCGGCGGCGGGGCAGTGAAACTACGGTAGCTGCCCCCTGAGCTGGTGGTGTGGCTTTGTGGGGAGGGCGTAGTT
CCTAATCCCCTTTCCGGGCAGCCGCCGGGGCTCGGGGCTGTGAGCGGCCGTGAGGCTGCCTCCCCGGGCCCCCTGCCTCCGCCATGTTCC
GCAGGGCACGCCTTAGCGTGAAGCCGAATGTCAGGCCTGGTGTAGGCGCCAGGGGCTCCACAGCTTCCAATCCCCAGCGTGGACGGGAGT
CTCCCAGGCCGCCGGATCCTGCCACGGACTCTGCTTCCAAGCCCGCGGAGCCCACAGATGTGCCCACAGTCGATTTCGGTGGAGCGGAGC
CCCAAGAAAAGGCTCCTAGGAGCAGTACTGAAAAGACTGGTGGTGACAATGATGTTGAAGAATCCAGTAGATCTTCCTCTACTGTTTCAC
AGAGAAGAAAGCGAATATCAAGTACTTCTAGCCTGGTTAAGTCTAGTGTCAGTGTTCCTTCAGAATCTCATCCCTTATCTACAATTAATC
AAGAGGCTCCACAGCCAACTGCCACTTCAACAAAAGAGAAACAGCCATGCTCAGACAGATACCGAATATACAAAGCCCAGAAACTGAGGG
AAATGTTAAAAGAAGAATTGAGAAAAGAGAAGAAACAATGGAAAAACAAATATGCTATAAATGAAAGTCAGAGGCCACCAGATCGTTCAA
AAATGACTATGAGAGACTTCATATATTATCTACCAGATAATAATCCAATGACTTCTTCACTGGAACAAGAAAAGAAAACTGAAAAGCCAT
CGACTCCAGTCCAGACAAGAGAGCAAGAAGGTAAGAGTACTCCTAATGCTGAAGATAATGAAATGGAAGAAGAGACAGATGATGGGCCAT
TACTGGTTCCTCGAGTAAAAGTGGCAGAAGATGGTTCCATTATTTTGGATGAAGAAAGTTTAACTGTAGAAGTTTTAAGAACAAAAGGCC
CTTGTGTTGTTGAAGAAAATGACCCCATATTTGAGCGCGGTTCTACAACTACATACTCCAGCTTTAGGAAAAACTATTACTCTAAACCAT
GGTCAAATAAAGAAACAGATATGTTTTTTTTAGCCATCAGCATGGTAGGAACTGACTTTTCTATGATCGGACAACTTTTTCCTCACAGAG
CAAGGATAGAAATTAAGGTTAAAGCGGCAACTGGGGAAGAAGTATCTGCTGAGGATCTTGGAGGTGCTGATCTTCATTGCAGAAAGTCTG
GAGTAAGTGACCACTGGGCTTTGGATGATCATCATGCCCTTCACTTAACTAGGAAGGTTGTGAGGAATCTAAATTATCAGAAGAAATTGG
ATGTCACCATTGAACCTTCTGAAGAGCCTTTATTTCCTGCTGATGAATTGTATGGAATAGTTGGTGCTAACCTTAAGAGGAGCTTTGATG
TCCGAGAGGTCATTGCTAGAATCGTGGATGGAAGCAGATTCACTGAGTTCAAAGCCTTTTATGGAGACACATTAGTTACAGGATTTGCTC
GAATATTTGGGTACCCAGTAGGTATCGTTGGAAACAACGGAGTTCTCTTTTCTGAATCTGCAAAAAAGGGTACTCACTTTGTCCAGTTAT
GCTGCCAAAGAAATATTCCTCTGCTGTTCCTTCAAAACATTACTGGATTTATGGTTGGTAGAGAGTATGAAGCTGAAGGAATTGCCAAGG
ATGGTGCCAAGATGGTGGCCGCTGTGGCCTGTGCCCAAGTGCCTAAGATAACCCTCATCATTGGGGGCTCCTATGGAGCCGGAAACTATG
GGATGTGTGGCAGAGCATATAGCCCAAGATTTCTCTACATTTGGCCAAATGCTCGTATCTCAGTGATGGGAGGAGAGCAGGCAGCCAATG
TGTTGGCCACGATAACAAAGGACCAAAGAGCCCGGGAAGGAAAGCAGTTCTCCAGTGCTGATGAAGCGGCTTTAAAAGAGCCCATCATTA
AGAAGTTTGAAGAGGAAGGAAACCCTTACTATTCCAGCGCAAGGGTATGGGATGATGGGATCATTGATCCAGCAGACACCAGACTGGTCT
TGGGTCTCAGTTTTAGTGCAGCCCTCAACGCACCAATAGAGAAGACTGACTTCGGTATCTTCAGGATGTAACTGGAATAAAGGATGTTTT
CTGTTGGACATGTACTGAAAATTAACACATGTAGTAGCCTTAAAATTTTAGACTTCTCGAACATGAGGCTGTTACAGTAATTTTTTTAAC
ACTGTGCATTGTACTTTTCTACCTTAAAAAAATCAGTGAGGATATTTATTTAATGAACATCAATTCCTTTTAAATTTTCTTAGAGAAATT
TCTCTGTGGCTCAGTTTTACCACCCATAAAGCGGAGACAGTAATTTACGGTTATCCTTTCTGACCCACAAAGTATGAAAAGTTCTGTAAT

>9570_9570_3_BDP1-MCCC2_BDP1_chr5_70766316_ENST00000358731_MCCC2_chr5_70927948_ENST00000323375_length(amino acids)=655AA_BP=0
MFRRARLSVKPNVRPGVGARGSTASNPQRGRESPRPPDPATDSASKPAEPTDVPTVDFGGAEPQEKAPRSSTEKTGGDNDVEESSRSSST
VSQRRKRISSTSSLVKSSVSVPSESHPLSTINQEAPQPTATSTKEKQPCSDRYRIYKAQKLREMLKEELRKEKKQWKNKYAINESQRPPD
RSKMTMRDFIYYLPDNNPMTSSLEQEKKTEKPSTPVQTREQEGKSTPNAEDNEMEEETDDGPLLVPRVKVAEDGSIILDEESLTVEVLRT
KGPCVVEENDPIFERGSTTTYSSFRKNYYSKPWSNKETDMFFLAISMVGTDFSMIGQLFPHRARIEIKVKAATGEEVSAEDLGGADLHCR
KSGVSDHWALDDHHALHLTRKVVRNLNYQKKLDVTIEPSEEPLFPADELYGIVGANLKRSFDVREVIARIVDGSRFTEFKAFYGDTLVTG
FARIFGYPVGIVGNNGVLFSESAKKGTHFVQLCCQRNIPLLFLQNITGFMVGREYEAEGIAKDGAKMVAAVACAQVPKITLIIGGSYGAG
NYGMCGRAYSPRFLYIWPNARISVMGGEQAANVLATITKDQRAREGKQFSSADEAALKEPIIKKFEEEGNPYYSSARVWDDGIIDPADTR

--------------------------------------------------------------
>9570_9570_4_BDP1-MCCC2_BDP1_chr5_70766316_ENST00000358731_MCCC2_chr5_70927948_ENST00000340941_length(transcript)=4075nt_BP=1277nt
AGTTGCGGCGTCCTGTGAGCGCGGGGATGCTGGGAGGAGGGTGAAATTTAGCCATCGGTGTGTGGCAGGGTCATGAAAAAGCGGCGGCGG
CGGGAGAGAGGAGGAGGCGGCGGCGGGGCAGTGAAACTACGGTAGCTGCCCCCTGAGCTGGTGGTGTGGCTTTGTGGGGAGGGCGTAGTT
CCTAATCCCCTTTCCGGGCAGCCGCCGGGGCTCGGGGCTGTGAGCGGCCGTGAGGCTGCCTCCCCGGGCCCCCTGCCTCCGCCATGTTCC
GCAGGGCACGCCTTAGCGTGAAGCCGAATGTCAGGCCTGGTGTAGGCGCCAGGGGCTCCACAGCTTCCAATCCCCAGCGTGGACGGGAGT
CTCCCAGGCCGCCGGATCCTGCCACGGACTCTGCTTCCAAGCCCGCGGAGCCCACAGATGTGCCCACAGTCGATTTCGGTGGAGCGGAGC
CCCAAGAAAAGGCTCCTAGGAGCAGTACTGAAAAGACTGGTGGTGACAATGATGTTGAAGAATCCAGTAGATCTTCCTCTACTGTTTCAC
AGAGAAGAAAGCGAATATCAAGTACTTCTAGCCTGGTTAAGTCTAGTGTCAGTGTTCCTTCAGAATCTCATCCCTTATCTACAATTAATC
AAGAGGCTCCACAGCCAACTGCCACTTCAACAAAAGAGAAACAGCCATGCTCAGACAGATACCGAATATACAAAGCCCAGAAACTGAGGG
AAATGTTAAAAGAAGAATTGAGAAAAGAGAAGAAACAATGGAAAAACAAATATGCTATAAATGAAAGTCAGAGGCCACCAGATCGTTCAA
AAATGACTATGAGAGACTTCATATATTATCTACCAGATAATAATCCAATGACTTCTTCACTGGAACAAGAAAAGAAAACTGAAAAGCCAT
CGACTCCAGTCCAGACAAGAGAGCAAGAAGGTAAGAGTACTCCTAATGCTGAAGATAATGAAATGGAAGAAGAGACAGATGATGGGCCAT
TACTGGTTCCTCGAGTAAAAGTGGCAGAAGATGGTTCCATTATTTTGGATGAAGAAAGTTTAACTGTAGAAGTTTTAAGAACAAAAGGCC
CTTGTGTTGTTGAAGAAAATGACCCCATATTTGAGCGCGGTTCTACAACTACATACTCCAGCTTTAGGAAAAACTATTACTCTAAACCAT
GGTCAAATAAAGAAACAGATATGTTTTTTTTAGCCATCAGCATGGTAGGAACTGACTTTTCTATGATCGGACAACTTTTTCCTCACAGAG
CAAGGATAGAAATTAAGGTTAAAGCGGCAACTGGGGAAGAAGTATCTGCTGAGGATCTTGGAGGTGCTGATCTTCATTGCAGAAAGTCTG
GAGTAAGTGACCACTGGGCTTTGGATGATCATCATGCCCTTCACTTAACTAGGAAGGTTGTGAGGAATCTAAATTATCAGAAGAAATTGG
ATGTCACCATTGAACCTTCTGAAGAGCCTTTATTTCCTGCTGATGAATTGTATGGAATAGTTGGTGCTAACCTTAAGAGGAGCTTTGATG
TCCGAGAGGTCATTGCTAGAATCGTGGATGGAAGCAGATTCACTGAGTTCAAAGCCTTTTATGGAGACACATTAGTTACAGGATTTGCTC
GAATATTTGGGTACCCAGTAGGTATCGTTGGAAACAACGGAGTTCTCTTTTCTGAATCTGCAAAAAAGGGTACTCACTTTGTCCAGTTAT
GCTGCCAAAGAAATATTCCTCTGCTGTTCCTTCAAAACATTACTGGATTTATGGTTGGTAGAGAGTATGAAGCTGAAGGAATTGCCAAGG
ATGGTGCCAAGATGGTGGCCGCTGTGGCCTGTGCCCAAGTGCCTAAGATAACCCTCATCATTGGGGGCTCCTATGGAGCCGGAAACTATG
GGATGTGTGGCAGAGCATATAGCCCAAGATTTCTCTACATTTGGCCAAATGCTCGTATCTCAGTGATGGGAGGAGAGCAGGCAGCCAATG
TGTTGGCCACGATAACAAAGGACCAAAGAGCCCGGGAAGGAAAGCAGTTCTCCAGTGCTGATGAAGCGGCTTTAAAAGAGCCCATCATTA
AGAAGTTTGAAGAGGAAGGAAACCCTTACTATTCCAGCGCAAGGGTATGGGATGATGGGATCATTGATCCAGCAGACACCAGACTGGTCT
TGGGTCTCAGTTTTAGTGCAGCCCTCAACGCACCAATAGAGAAGACTGACTTCGGTATCTTCAGGATGTAACTGGAATAAAGGATGTTTT
CTGTTGGACATGTACTGAAAATTAACACATGTAGTAGCCTTAAAATTTTAGACTTCTCGAACATGAGGCTGTTACAGTAATTTTTTTAAC
ACTGTGCATTGTACTTTTCTACCTTAAAAAAATCAGTGAGGATATTTATTTAATGAACATCAATTCCTTTTAAATTTTCTTAGAGAAATT
TCTCTGTGGCTCAGTTTTACCACCCATAAAGCGGAGACAGTAATTTACGGTTATCCTTTCTGACCCACAAAGTATGAAAAGTTCTGTAAT
CTGTAAACTCAGTTCTGTAATCTGTATTATTGAGATGATTAATATAAAGTTGTATTTTCACTGAAATGATTGTTTTGCTGGTTATGCTTG
GTGATATTTTAGCGGGCTTATTTTTGAAAGGCATCTGTTACTTCAGTGGCATAAAGTGCCCTCACACTGCTGTGCAGCCATCACCACCAT
TCATCTCCAGAATTTGTTCTCAGTCCCAAACTGAAACTATACCATTCAAACAACAGCGCTCCCCATTTCCCCCTCCCCCGAGCCCATGAC
ATCTCCTTATTATTATTTTTTTTTTGAGACAGGGTGTTTCTCTGTTGCCCAGGCTGGAGTGCGGTGGTGTGATCTCGGCTCACTGCAGCT
TCCACCTCCCGGGTTCAAGCGATTCTTGTGCCTCAGCCTCCCAAGCAGCTGGGACTATAGGCACGCACCACCACACCCAGCTAAGTTCTG
TATTTTTAGCAGAGACGGGATTTCACTAGGTTGCCCAGGCTGGTCTCAAACTACTGACCTCAAGTGATCCACCCGCCTCGGCCTCCCAAA
GTGCTGGGATTACAGGTGTGAGCCACCGCGCCTGACCACATCTCCTTATTCTTAAATGTATGTGTTTCTCATGGTTTGATTTATTCTTGC
TGGGCCATTTCAGCCCCTGTCATGGCTTCACTCGCCATCTAAATGCAGATGATTACTGCCTTGACGGTTCTTAACCCAGCTCTCCCCTGA
GCTGCAGGCCTGCATATCCAGTAGGTCTACTGGACATCTGTACTGGTTGTTGTGGAGGAACCTCTGGCTTGCTCATTAAGTCCTACTGAT
TTTCACTATCCCCTGAATTTCCCCACTTATTTTTGTCTTTCACTATCGCAGGCCTTAGAAGAGGTCTACCTGCCTCCAGTCTTACCTAGT
CCAGTCTACCCCCTGGAGTTAGAATGGCCATCCTGAAGTGAAAAGTAATGTCAGATTACTCCCTTCAGTGATTTCTTGTAGAAGTGCCAA
TCCCTGAATGCCACCAAGATCTTAATCTTCACATCTTTAATCTTATCTCTTTGACTCCTCTTTACACCGGAGAACGGCTCCAGCTGTTCT
AGCTCTCTTTCAGTTCTTTGAACCTTCCCACCTTAGGGTCTATAAGGTTCCCTCTGCCCAAATTGTTCTACTCTCCCTTCTTCTTCAACA
CATCCTTCAGTTTAAGCACTTGCTTCTCTCAGTTTAAACTCCACTTCCTTAGGGATGTCTCTGTGACCTCCCTGTGCTGGATTAGCTTCC
CTACTCTATGCTCTTGTAAAACACTATCTACTTCCTTTGTCATAAACTCATCATTTTCCTATAAACATTAATATTGTCCTCCTGCTAGAA
TGTAAGCTCCGTGAGAGCAAGGATCCTCCTGTTTACCCTGTACCTCCAATGTCTGGCACTTGTAGGTGCTCAAATATTCGTTGAATGAAT
GAAAAATCCATATTGTAATTGATGTCCTCTGGCCACATAGTTTTAAAATTAGGTGATTGATTATATGACCGAATAGAACTATCAAATGTT

>9570_9570_4_BDP1-MCCC2_BDP1_chr5_70766316_ENST00000358731_MCCC2_chr5_70927948_ENST00000340941_length(amino acids)=655AA_BP=0
MFRRARLSVKPNVRPGVGARGSTASNPQRGRESPRPPDPATDSASKPAEPTDVPTVDFGGAEPQEKAPRSSTEKTGGDNDVEESSRSSST
VSQRRKRISSTSSLVKSSVSVPSESHPLSTINQEAPQPTATSTKEKQPCSDRYRIYKAQKLREMLKEELRKEKKQWKNKYAINESQRPPD
RSKMTMRDFIYYLPDNNPMTSSLEQEKKTEKPSTPVQTREQEGKSTPNAEDNEMEEETDDGPLLVPRVKVAEDGSIILDEESLTVEVLRT
KGPCVVEENDPIFERGSTTTYSSFRKNYYSKPWSNKETDMFFLAISMVGTDFSMIGQLFPHRARIEIKVKAATGEEVSAEDLGGADLHCR
KSGVSDHWALDDHHALHLTRKVVRNLNYQKKLDVTIEPSEEPLFPADELYGIVGANLKRSFDVREVIARIVDGSRFTEFKAFYGDTLVTG
FARIFGYPVGIVGNNGVLFSESAKKGTHFVQLCCQRNIPLLFLQNITGFMVGREYEAEGIAKDGAKMVAAVACAQVPKITLIIGGSYGAG
NYGMCGRAYSPRFLYIWPNARISVMGGEQAANVLATITKDQRAREGKQFSSADEAALKEPIIKKFEEEGNPYYSSARVWDDGIIDPADTR

--------------------------------------------------------------
>9570_9570_5_BDP1-MCCC2_BDP1_chr5_70766316_ENST00000358731_MCCC2_chr5_70927948_ENST00000509358_length(transcript)=1657nt_BP=1277nt
AGTTGCGGCGTCCTGTGAGCGCGGGGATGCTGGGAGGAGGGTGAAATTTAGCCATCGGTGTGTGGCAGGGTCATGAAAAAGCGGCGGCGG
CGGGAGAGAGGAGGAGGCGGCGGCGGGGCAGTGAAACTACGGTAGCTGCCCCCTGAGCTGGTGGTGTGGCTTTGTGGGGAGGGCGTAGTT
CCTAATCCCCTTTCCGGGCAGCCGCCGGGGCTCGGGGCTGTGAGCGGCCGTGAGGCTGCCTCCCCGGGCCCCCTGCCTCCGCCATGTTCC
GCAGGGCACGCCTTAGCGTGAAGCCGAATGTCAGGCCTGGTGTAGGCGCCAGGGGCTCCACAGCTTCCAATCCCCAGCGTGGACGGGAGT
CTCCCAGGCCGCCGGATCCTGCCACGGACTCTGCTTCCAAGCCCGCGGAGCCCACAGATGTGCCCACAGTCGATTTCGGTGGAGCGGAGC
CCCAAGAAAAGGCTCCTAGGAGCAGTACTGAAAAGACTGGTGGTGACAATGATGTTGAAGAATCCAGTAGATCTTCCTCTACTGTTTCAC
AGAGAAGAAAGCGAATATCAAGTACTTCTAGCCTGGTTAAGTCTAGTGTCAGTGTTCCTTCAGAATCTCATCCCTTATCTACAATTAATC
AAGAGGCTCCACAGCCAACTGCCACTTCAACAAAAGAGAAACAGCCATGCTCAGACAGATACCGAATATACAAAGCCCAGAAACTGAGGG
AAATGTTAAAAGAAGAATTGAGAAAAGAGAAGAAACAATGGAAAAACAAATATGCTATAAATGAAAGTCAGAGGCCACCAGATCGTTCAA
AAATGACTATGAGAGACTTCATATATTATCTACCAGATAATAATCCAATGACTTCTTCACTGGAACAAGAAAAGAAAACTGAAAAGCCAT
CGACTCCAGTCCAGACAAGAGAGCAAGAAGGTAAGAGTACTCCTAATGCTGAAGATAATGAAATGGAAGAAGAGACAGATGATGGGCCAT
TACTGGTTCCTCGAGTAAAAGTGGCAGAAGATGGTTCCATTATTTTGGATGAAGAAAGTTTAACTGTAGAAGTTTTAAGAACAAAAGGCC
CTTGTGTTGTTGAAGAAAATGACCCCATATTTGAGCGCGGTTCTACAACTACATACTCCAGCTTTAGGAAAAACTATTACTCTAAACCAT
GGTCAAATAAAGAAACAGATATGTTTTTTTTAGCCATCAGCATGGTAGGAACTGACTTTTCTATGATCGGACAACTTTTTCCTCACAGAG
CAAGGATAGAAATTAAGGTTAAAGCGGCAACTGGGGAAGAAGTATCTGCTGAGGATCTTGGAGGTGCTGATCTTCATTGCAGAAAGTCTG
GAGTAAGTGACCACTGGGCTTTGGATGATCATCATGCCCTTCACTTAACTAGGAAGGTTGTGAGGAATCTAAATTATCAGAAGAAATTGG
ATGTCACCATTGAACCTTCTGAAGAGCCTTTATTTCCTGCTGATGAATTGTATGGAATAGTTGGTGCTAACCTTAAGAGGAGCTTTGATG
TCCGAGAGGTCATTGCTAGAATCGTGGATGGAAGCAGATTCACTGAGTTCAAAGCCTTTTATGGAGACACATTAGTTACAGGTATAAAGG

>9570_9570_5_BDP1-MCCC2_BDP1_chr5_70766316_ENST00000358731_MCCC2_chr5_70927948_ENST00000509358_length(amino acids)=455AA_BP=0
MFRRARLSVKPNVRPGVGARGSTASNPQRGRESPRPPDPATDSASKPAEPTDVPTVDFGGAEPQEKAPRSSTEKTGGDNDVEESSRSSST
VSQRRKRISSTSSLVKSSVSVPSESHPLSTINQEAPQPTATSTKEKQPCSDRYRIYKAQKLREMLKEELRKEKKQWKNKYAINESQRPPD
RSKMTMRDFIYYLPDNNPMTSSLEQEKKTEKPSTPVQTREQEGKSTPNAEDNEMEEETDDGPLLVPRVKVAEDGSIILDEESLTVEVLRT
KGPCVVEENDPIFERGSTTTYSSFRKNYYSKPWSNKETDMFFLAISMVGTDFSMIGQLFPHRARIEIKVKAATGEEVSAEDLGGADLHCR
KSGVSDHWALDDHHALHLTRKVVRNLNYQKKLDVTIEPSEEPLFPADELYGIVGANLKRSFDVREVIARIVDGSRFTEFKAFYGDTLVTG

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Fusion Gene PPI Analysis for BDP1-MCCC2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
HgeneBDP1chr5:70766316chr5:70922467ENST00000358731+7391_299338.02625.0ZBTB43
HgeneBDP1chr5:70766316chr5:70927948ENST00000358731+7391_299338.02625.0ZBTB43


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneBDP1chr5:70766316chr5:70922467ENST00000380675+7381_29901360.6666666666667ZBTB43
HgeneBDP1chr5:70766316chr5:70927948ENST00000380675+7381_29901360.6666666666667ZBTB43


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for BDP1-MCCC2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for BDP1-MCCC2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneBDP1C3711374Nonsyndromic Deafness1CLINGEN
TgeneC18594993-methylcrotonyl CoA carboxylase 2 deficiency12CTD_human;GENOMICS_ENGLAND;UNIPROT
TgeneC02686003-methylcrotonyl CoA carboxylase 1 deficiency6CLINGEN;ORPHANET