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in Kim Lab

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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:BBX-WBSCR17 (FusionGDB2 ID:HG56987TG64409)

Fusion Gene Summary for BBX-WBSCR17

check button Fusion gene summary
Fusion gene informationFusion gene name: BBX-WBSCR17
Fusion gene ID: hg56987tg64409
HgeneTgene
Gene symbol

BBX

WBSCR17

Gene ID

56987

64409

Gene nameBBX high mobility group box domain containingpolypeptide N-acetylgalactosaminyltransferase 17
SynonymsARTC1|HBP2|HSPC339|MDS001GALNACT17|GALNT16|GALNT20|GALNTL3|GalNAc-T17|GalNAc-T19|GalNAc-T5L|WBSCR17
Cytomap('BBX')('WBSCR17')

3q13.12

7q11.22

Type of geneprotein-codingprotein-coding
DescriptionHMG box transcription factor BBXAg recognized by Treg cells 1BBX, HMG-box containingHMG box-containing protein 2bobby sox homologx 001 proteinpolypeptide N-acetylgalactosaminyltransferase 17UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase-like 3UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase-like protein 3UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminylt
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000325805, ENST00000402543, 
ENST00000406780, ENST00000415149, 
ENST00000416476, ENST00000473542, 
Fusion gene scores* DoF score14 X 12 X 8=13445 X 3 X 5=75
# samples 175
** MAII scorelog2(17/1344*10)=-2.98292648664106
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(5/75*10)=-0.584962500721156
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: BBX [Title/Abstract] AND WBSCR17 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointBBX(107517567)-WBSCR17(70800536), # samples:2
Anticipated loss of major functional domain due to fusion event.BBX-WBSCR17 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
BBX-WBSCR17 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
BBX-WBSCR17 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
BBX-WBSCR17 seems lost the major protein functional domain in Hgene partner, which is a transcription factor due to the frame-shifted ORF.
BBX-WBSCR17 seems lost the major protein functional domain in Tgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across BBX (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across WBSCR17 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-E2-A15M-01ABBXchr3

107517567

+WBSCR17chr7

70800536

+


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Fusion Gene ORF analysis for BBX-WBSCR17

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000325805ENST00000498380BBXchr3

107517567

+WBSCR17chr7

70800536

+
5CDS-3UTRENST00000402543ENST00000498380BBXchr3

107517567

+WBSCR17chr7

70800536

+
5CDS-3UTRENST00000406780ENST00000498380BBXchr3

107517567

+WBSCR17chr7

70800536

+
5CDS-3UTRENST00000415149ENST00000498380BBXchr3

107517567

+WBSCR17chr7

70800536

+
5CDS-3UTRENST00000416476ENST00000498380BBXchr3

107517567

+WBSCR17chr7

70800536

+
Frame-shiftENST00000416476ENST00000333538BBXchr3

107517567

+WBSCR17chr7

70800536

+
In-frameENST00000325805ENST00000333538BBXchr3

107517567

+WBSCR17chr7

70800536

+
In-frameENST00000402543ENST00000333538BBXchr3

107517567

+WBSCR17chr7

70800536

+
In-frameENST00000406780ENST00000333538BBXchr3

107517567

+WBSCR17chr7

70800536

+
In-frameENST00000415149ENST00000333538BBXchr3

107517567

+WBSCR17chr7

70800536

+
intron-3CDSENST00000473542ENST00000333538BBXchr3

107517567

+WBSCR17chr7

70800536

+
intron-3UTRENST00000473542ENST00000498380BBXchr3

107517567

+WBSCR17chr7

70800536

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)
BP loci
(transcript)
Predicted start
(transcript)
Predicted stop
(transcript)
Seq length
(amino acids)
ENST00000415149BBXchr3107517567+ENST00000333538WBSCR17chr770800536+5800278831543461343
ENST00000402543BBXchr3107517567+ENST00000333538WBSCR17chr770800536+5832282041943781319
ENST00000325805BBXchr3107517567+ENST00000333538WBSCR17chr770800536+5850283827543961373
ENST00000406780BBXchr3107517567+ENST00000333538WBSCR17chr770800536+6010299853745561339

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000415149ENST00000333538BBXchr3107517567+WBSCR17chr770800536+0.0008463870.9991536
ENST00000402543ENST00000333538BBXchr3107517567+WBSCR17chr770800536+0.0008878570.99911207
ENST00000325805ENST00000333538BBXchr3107517567+WBSCR17chr770800536+0.0005726220.99942744
ENST00000406780ENST00000333538BBXchr3107517567+WBSCR17chr770800536+0.0008525080.99914753

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Fusion Genomic Features for BBX-WBSCR17


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
BBXchr3107517567+WBSCR17chr770800535+6.65E-070.9999993
BBXchr3107517567+WBSCR17chr770800535+6.65E-070.9999993

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for BBX-WBSCR17


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr3:107517567/chr7:70800536)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneBBXchr3:107517567chr7:70800536ENST00000325805+1618326_370850942.0Coiled coilOntology_term=ECO:0000255
HgeneBBXchr3:107517567chr7:70800536ENST00000406780+1416326_370820912.0Coiled coilOntology_term=ECO:0000255
HgeneBBXchr3:107517567chr7:70800536ENST00000415149+1517326_370820912.0Coiled coilOntology_term=ECO:0000255
HgeneBBXchr3:107517567chr7:70800536ENST00000325805+161841_50850942.0Compositional biasNote=Poly-Glu
HgeneBBXchr3:107517567chr7:70800536ENST00000325805+1618446_542850942.0Compositional biasNote=Lys-rich
HgeneBBXchr3:107517567chr7:70800536ENST00000325805+1618671_773850942.0Compositional biasNote=Lys-rich
HgeneBBXchr3:107517567chr7:70800536ENST00000406780+141641_50820912.0Compositional biasNote=Poly-Glu
HgeneBBXchr3:107517567chr7:70800536ENST00000406780+1416446_542820912.0Compositional biasNote=Lys-rich
HgeneBBXchr3:107517567chr7:70800536ENST00000406780+1416671_773820912.0Compositional biasNote=Lys-rich
HgeneBBXchr3:107517567chr7:70800536ENST00000415149+151741_50820912.0Compositional biasNote=Poly-Glu
HgeneBBXchr3:107517567chr7:70800536ENST00000415149+1517446_542820912.0Compositional biasNote=Lys-rich
HgeneBBXchr3:107517567chr7:70800536ENST00000415149+1517671_773820912.0Compositional biasNote=Lys-rich
HgeneBBXchr3:107517567chr7:70800536ENST00000325805+161880_148850942.0DNA bindingHMG box
HgeneBBXchr3:107517567chr7:70800536ENST00000406780+141680_148820912.0DNA bindingHMG box
HgeneBBXchr3:107517567chr7:70800536ENST00000415149+151780_148820912.0DNA bindingHMG box
TgeneWBSCR17chr3:107517567chr7:70800536ENST00000333538011465_59479599.0DomainRicin B-type lectin
TgeneWBSCR17chr3:107517567chr7:70800536ENST00000333538011151_26279599.0RegionNote=Catalytic subdomain A
TgeneWBSCR17chr3:107517567chr7:70800536ENST00000333538011319_38179599.0RegionNote=Catalytic subdomain B

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneWBSCR17chr3:107517567chr7:70800536ENST000003335380111_679599.0Topological domainCytoplasmic
TgeneWBSCR17chr3:107517567chr7:70800536ENST0000033353801128_59879599.0Topological domainLumenal
TgeneWBSCR17chr3:107517567chr7:70800536ENST000003335380117_2779599.0TransmembraneHelical%3B Signal-anchor for type II membrane protein


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Fusion Gene Sequence for BBX-WBSCR17


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>9129_9129_1_BBX-WBSCR17_BBX_chr3_107517567_ENST00000325805_WBSCR17_chr7_70800536_ENST00000333538_length(transcript)=5850nt_BP=2838nt
ATGTGGAGCAGTGTACAGTGAAGCGGAGGCAGAGCGGCTCCGCGAGCTTCTCTCCACTTTCCCATAGAGAAACCCTGACTGGCCGCTGAG
GGCTAGCTACACACACGCCCTCACGCCCGGCGAGCCCGCGAGGTCACTATCATATGACAAAGGCTTTGCCGCAGTTCATCTTCCTCCCTG
TGTACTTTCCATTTGCCTTCCTGGAATCCTGCTGCATCACAGAAGCTGGAAGTTCTGATGTTCCACTGAAATCACAATGGAAAGTCTTGA
CTTGACTGGTCACAGTAATGAAAGGCAGTAATAGAAATAAGGATCATTCAGCAGAAGGAGAAGGGGTTGGAAAACGACCAAAACGAAAGT
GTCTTCAGTGGCATCCATTGCTAGCAAAGAAACTTCTTGATTTTTCAGAAGAGGAAGAAGAGGAAGACGAAGAGGAGGATATTGATAAGG
TTCAACTTCTTGGGGCCGATGGCCTAGAGCAAGATGTTGGTGAAACTGAAGATGATGAATCACCAGAGCAGCGAGCCCGGAGACCAATGA
ATGCATTTCTTTTATTTTGCAAACGCCATCGCTCTCTTGTACGTCAGGAACACCCCAGGCTTGATAACCGAGGTGCTACCAAGATACTAG
CTGATTGGTGGGCTGTTCTTGATCCAAAGGAAAAGCAGAAATACACAGACATGGCCAAGGAGTATAAGGATGCATTTATGAAAGCAAATC
CTGGCTACAAATGGTGTCCTACCACAAACAAGCCTGTGAAATCCCCAACACCCACTGTCAATCCACGAAAGAAACTTTGGGCCTTCCCAT
CTGACTCTTCAAGAGACTTGCCAAGCCCCAAGAAAGCAAAGACTGAAGAAATGCCTCAGCTTAACTTTGGAATGGCTGATCCTACTCAAA
TGGGAGGCCTGAGTATGCTGCTGTTAGCTGGAGAACATGCTCTTGGCACACCAGAGGTATCCTCTGGCACATGCAGGCCTGATGTTTCAG
AATCTCCTGAATTACGTCAGAAGTCACCATTGTTTCAGTTTGCCGAGATATCTTCAAGTACGTCCCACTCTGATGCTTCTACAAAGCAGT
GTCAAACATCTGCCTTGTTTCAGTTTGCAGAGATTTCTTCAAACACTTCGCAGTTGGGTGGTGCTGAGCCTGTAAAACGCTGTGGAAAGT
CTGCACTCTTTCAACTGGCAGAGATGTGCCTGGCATCAGAAGGGATGAAAATGGAAGAATCAAAGCTAATAAAAGCAAAAGAATCCGATG
GTGGAAGAATTAAAGAATTAGAGAAGGGAAAGGAAGAAAAAGAAATTAAAATGGAGAAAACAGATGAAACTAGGTTACAGAAGGAAGCAG
AATTTGAAAAATCGGCTAAGGAAAATTTAAGAGATTCTAAGGAATTGAGAAATTTTGAGGCATTGCAAATAGATGACATAATGGCTATAA
AAATGGAAGATCCCAAAGAAATTAGAAAGGAAGAGTTAGAAGAAGATCACAAATGTAGTCATTTTCCTGATTTTTCTTATTCTGCCAGTA
GCAAGATAATAATTAGTGATGTTCCCAGTAGAAAGGATCATATGTGCCATCCTCATGGAATTATGATCATTGAGGATCCCGCAGCATTAA
ACAAGCCAGAAAAGCTAAAAAAGAAAAAGAAGAAAAGCAAAATGGATCGACATGGAAATGATAAATCCACACCCAAGAAGACTTGCAAAA
AGAGGCAGTCTTCGGAATCTGACATTGAGAGCGTCATATATACCATTGAAGCCGTCGCAAAAGGAGACTGGGGCATAGAGAAACTTGGAG
ATACCCCTCGCAAGAAGGTCCGCACATCCTCAAGTGGCAAGGGAAGCATTTTGGATGCCAAGCCACCAAAGAAAAAAGTGAAATCAAGAG
AGAAGAAAATGTCAAAGGAGAAATCCTCAGACACCACCAAAGAGTCAAGACCTCCAGATTTCATTAGTATTTCTGCTAGCAAGAACATTT
CTGGTGAGACACCAGAGGGTATAAAAGCAGAACCATTGACCCCTATGGAAGATGCACTACCACCCAGCCTATCAGGACAGGCCAAGCCTG
AGGACAGTGACTGTCACAGAAAAATAGAAACTTGTGGTTCCAGGAAATCCGAGAGGTCTTGCAAAGGTGCTCTTTATAAAACCCTGGTGT
CTGAGGGCATGCTCACCTCTCTGCGAGCTAATGTTGACAGAGGAAAACGAAGCTCAGGAAAAGGAAACTCCTCTGATCATGAAGGGTGTT
GGAATGAAGAAAGCTGGACATTTAGTCAGAGTGGGACCAGTGGGAGCAAGAAGTTCAAGAAGACAAAGCCAAAAGAAGACTGTCTCCTTG
GCTCCGCAAAGCTGGATGAAGAATTTGAAAAAAAATTCAACAGCCTCCCTCAATATAGTCCTGTTACATTTGACCGGAAATGTGTACCTG
TCCCAAGAAAAAAGAAGAAGACTGGAAATGTGTCCTCAGAACCGACTAAAACCAGCAAAGGTCCTTTCCAGTCTCAGAAAAAGAACTTAT
TCCACAAAATTGTCAGCAAATATAAGCACAAAAAGGAGAAGCCCAATGTTCCGGAAAAAGGAAGTGGGGATAAATGGTCAAACAAGCAAC
TCTTCTTGGATGCCATTCACCCTACAGAAGCCATATTTTCAGAAGACAGAAACACCATGGAGCCTGTTCATAAGGTTAAAAATATCCCAT
CCATTTTCAACACTCCAGAGCCAACAACAACGCAAGAACCTTTGGTGGGCAGCCAAAAGAGAAAAGCAAGGAAAACCAAGATTACACACC
TTGTCAGGACAGCAGATGGCCGGGTATCACCAGCAGGAGGTACTTTGGGCTTATCCAAATCCCTTGGGCTCATTGAAGGTTATGGTGGGC
GGGGTAAAGGGGGCCTTCCGGCTACTCTTTCCCCGGCTGAAGAAGAAAAGGCTAAGGGACCCCATGAGAAGTATGGCTACAATTCATACC
TCAGTGAAAAAATTTCACTGGACCGTTCCATTCCGGATTATCGTCCCACCAAGTGTAAGGAGCTCAAGTACTCCAAGGACCTGCCCCAGA
TATCCATCATATTCATCTTCGTGAACGAGGCCCTGTCGGTGATCCTGCGGTCCGTGCACAGTGCCGTCAATCACACGCCCACACACCTGC
TGAAGGAAATCATTCTGGTGGATGACAACAGCGACGAAGAGGAGCTGAAGGTCCCCCTAGAGGAGTATGTCCACAAACGCTACCCCGGGC
TGGTGAAGGTGGTAAGAAATCAGAAGAGGGAAGGCCTGATCCGCGCTCGCATTGAGGGCTGGAAGGTGGCTACCGGGCAGGTCACTGGCT
TCTTTGATGCCCACGTGGAATTCACCGCTGGCTGGGCTGAGCCGGTTCTATCCCGCATCCAGGAAAACCGGAAGCGTGTGATCCTCCCCT
CCATTGACAACATCAAACAGGACAACTTTGAGGTGCAGCGGTACGAGAACTCGGCCCACGGGTACAGCTGGGAGCTGTGGTGCATGTACA
TCAGCCCCCCAAAAGACTGGTGGGACGCCGGAGACCCTTCTCTCCCCATCAGGACCCCAGCCATGATAGGCTGCTCGTTCGTGGTCAACA
GGAAGTTCTTCGGTGAAATTGGTCTTCTGGATCCTGGCATGGATGTATACGGAGGAGAAAATATTGAACTGGGAATCAAGGTATGGCTCT
GTGGGGGCAGCATGGAGGTCCTTCCTTGCTCACGGGTGGCCCACATTGAGCGGAAGAAGAAGCCATATAATAGCAACATTGGCTTCTACA
CCAAGAGGAATGCTCTTCGCGTTGCTGAGGTCTGGATGGACGATTACAAGTCTCATGTGTACATAGCGTGGAACCTGCCGCTGGAGAATC
CGGGAATTGACATCGGTGATGTCTCCGAAAGAAGAGCATTAAGGAAAAGTTTAAAGTGTAAGAATTTCCAGTGGTACCTGGACCATGTTT
ACCCAGAAATGAGAAGATACAATAATACCGTTGCTTACGGGGAGCTTCGCAACAACAAGGCAAAAGACGTCTGCTTGGACCAGGGGCCGC
TGGAGAACCACACAGCAATATTGTATCCGTGCCATGGCTGGGGACCACAGCTTGCCCGCTACACCAAGGAAGGCTTCCTGCACTTGGGTG
CCCTGGGGACCACCACACTCCTCCCTGACACCCGCTGCCTGGTGGACAACTCCAAGAGTCGGCTGCCCCAGCTCCTGGACTGCGACAAGG
TCAAGAGCAGCCTGTACAAGCGCTGGAACTTCATCCAGAATGGAGCCATCATGAACAAGGGCACGGGACGCTGCCTGGAGGTGGAGAACC
GGGGCCTGGCTGGCATCGACCTCATCCTCCGCAGCTGCACAGGTCAGAGGTGGACCATTAAGAACTCCATCAAGTAGAGGGAGGGAGCTG
GGGCACTGGAGCCTGGCCCCCAGGACATGGCTGCTCCCCCCAACATCTGGACCAGCTGCCCTGGCGGAGAGACAGCAAGGGGCCGGCAGG
TGCTCGATGGGCCCCCCAGGGCTTCTCCAGGGCAGCACAGGGACCCCGGATGAAGACTCTGTCCCCCCTCAGGCATTCAGCTGCCCACAA
GTTTCCTGCACCCTGGAAAAGCCCCCCACCCTTCCTCTGGGAAACTGACAGCTGTCTTCCACAGCCTCTGATGTGGACCTGGTACTGAGG
AGCAAGACTGTCCAGTTCTCCTCCACATCTCCCATCCCAGAATCAGGATCTGGGACTGGCAGGGTCCCCTCCTGTGTCTCATCTCTTGCA
GCAGCAGCTGCTGAACTCCAGCCATCAACACGGTGGGAGGCAGCGGGGGCTTCAGCCATGTCCTAGCTCCCCGCCCTAAAAGGAGGCAGT
GAGGACCAGGCACTATTTCCTCCGAGGTTACTTCTACCCAGATGACACCTGCCTGTTCACGCCCCAAGGCAGCTACTGCCCCTAACCCTT
CCCACCAGGGTAGCTTTGGGCACTGCAGCTCTGGACTTTTCTGGCCCCTCCTGAGATGACCTGATGGAGCTGATGCTTTCTCTCCTAATC
CCTGGGCACTAGGCTCTTATCAGTGTGCTTGGGCCAGCTCTCCTGCCTGTGTCTAGAGGAAGCCAGAGACAGAAATAGGCTAAGCCTGCA
GTAGGATCTCAGCCACAAGGGCCCCGCAGGATGGAGCTGGGTCAAGGACCAGGGAGCCCTGACTCCCAGAGGCTGCCACCGGGGAGAAGC
AGCGGTCCTCCATCCAGAACCTAAGGGCTGAAGCAAAGGCTGCCAGGACCCTTGAAGATGCTTTTGGCTCACCTCATTTCACCCCACGCT
CTGCTGGCTGGCAGAGGAGAAGGCAGTCGTTTCCTCTCTGAAGAGTATTTTTTTCGATTGCCCTCTGGTTAGGGTGCACATATAAATCAG
AGTTAATATATGAACGCGTGTGCATGCACAAGTGTGTGTGTGCCTGCGTGCTGTGCGTGGCAGGGTGTGTGTGTGTGTGTCTGGCTGTGC
GTTCCGGAGTGTGTGACGATGCTGACCTAGCTGTGTGGCCTTGGGCTTGCTGCTTCATTACTCACCTGGATGGGGACGAGGGATGAGAAG
GGTGTGGGTTTGGCCCCATGTCACTGGCCGGAAGGATGTGTCTCAGCCCTGCCCTGTGGGGTGCCCCCGATGGGAGGCTGTCCCATCTCC
CAGTCCCCATCTCTTTTTCCCCACACTGTCCCTGGCCAAGCCCTGCCCAGAGCTGAACCCTGTAGCTGCCCCCTTGCCCTGTGTGGGATT
CGCAGTGTCTCATTTGGTGACGTCTTACTGGTGATCATCTCCTCACCCCATCTCCCACCTTGTGGAATAAATACATGTTAGCACTTCCCA

>9129_9129_1_BBX-WBSCR17_BBX_chr3_107517567_ENST00000325805_WBSCR17_chr7_70800536_ENST00000333538_length(amino acids)=1373AA_BP=853
MVTVMKGSNRNKDHSAEGEGVGKRPKRKCLQWHPLLAKKLLDFSEEEEEEDEEEDIDKVQLLGADGLEQDVGETEDDESPEQRARRPMNA
FLLFCKRHRSLVRQEHPRLDNRGATKILADWWAVLDPKEKQKYTDMAKEYKDAFMKANPGYKWCPTTNKPVKSPTPTVNPRKKLWAFPSD
SSRDLPSPKKAKTEEMPQLNFGMADPTQMGGLSMLLLAGEHALGTPEVSSGTCRPDVSESPELRQKSPLFQFAEISSSTSHSDASTKQCQ
TSALFQFAEISSNTSQLGGAEPVKRCGKSALFQLAEMCLASEGMKMEESKLIKAKESDGGRIKELEKGKEEKEIKMEKTDETRLQKEAEF
EKSAKENLRDSKELRNFEALQIDDIMAIKMEDPKEIRKEELEEDHKCSHFPDFSYSASSKIIISDVPSRKDHMCHPHGIMIIEDPAALNK
PEKLKKKKKKSKMDRHGNDKSTPKKTCKKRQSSESDIESVIYTIEAVAKGDWGIEKLGDTPRKKVRTSSSGKGSILDAKPPKKKVKSREK
KMSKEKSSDTTKESRPPDFISISASKNISGETPEGIKAEPLTPMEDALPPSLSGQAKPEDSDCHRKIETCGSRKSERSCKGALYKTLVSE
GMLTSLRANVDRGKRSSGKGNSSDHEGCWNEESWTFSQSGTSGSKKFKKTKPKEDCLLGSAKLDEEFEKKFNSLPQYSPVTFDRKCVPVP
RKKKKTGNVSSEPTKTSKGPFQSQKKNLFHKIVSKYKHKKEKPNVPEKGSGDKWSNKQLFLDAIHPTEAIFSEDRNTMEPVHKVKNIPSI
FNTPEPTTTQEPLVGSQKRKARKTKITHLVRTADGRVSPAGGTLGLSKSLGLIEGYGGRGKGGLPATLSPAEEEKAKGPHEKYGYNSYLS
EKISLDRSIPDYRPTKCKELKYSKDLPQISIIFIFVNEALSVILRSVHSAVNHTPTHLLKEIILVDDNSDEEELKVPLEEYVHKRYPGLV
KVVRNQKREGLIRARIEGWKVATGQVTGFFDAHVEFTAGWAEPVLSRIQENRKRVILPSIDNIKQDNFEVQRYENSAHGYSWELWCMYIS
PPKDWWDAGDPSLPIRTPAMIGCSFVVNRKFFGEIGLLDPGMDVYGGENIELGIKVWLCGGSMEVLPCSRVAHIERKKKPYNSNIGFYTK
RNALRVAEVWMDDYKSHVYIAWNLPLENPGIDIGDVSERRALRKSLKCKNFQWYLDHVYPEMRRYNNTVAYGELRNNKAKDVCLDQGPLE
NHTAILYPCHGWGPQLARYTKEGFLHLGALGTTTLLPDTRCLVDNSKSRLPQLLDCDKVKSSLYKRWNFIQNGAIMNKGTGRCLEVENRG

--------------------------------------------------------------
>9129_9129_2_BBX-WBSCR17_BBX_chr3_107517567_ENST00000402543_WBSCR17_chr7_70800536_ENST00000333538_length(transcript)=5832nt_BP=2820nt
GGTTGCATGTACTGTATGTGGAGCAGTGTACAGTGAAGCGGAGGCAGAGCGGCTCCGCGAGCTTCTCTCCACTTTCCCATAGAGAAACCC
TGACTGGCCGCTGAGGGCTAGCTACACACACGCCCTCACGCCCGGCGAGCCCGCGAGGTCACTATCATATGACAAAGGCTTTGCCGCAGT
TCATCTTCCTCCCTGTGTACTTTCCATTTGCCTTCCTGGAATCCTGCTGCATCACAGAAGCTGGAAGTTCTGATGTTCCACTGAAATCAC
AATGGAAAGTCTTGACTTGACTGGCACCCTCAGGAAGACCCCAAGCCTCTAGCAGTACCTGGTATCATCTCCAGCATGTTATAGATGTGG
AGGATTCACTGGGATATTGAGAAATACCAGAGGCGAATTGTTCCACTGTAGTCACAGTAATGAAAGGCAGTAATAGAAATAAGGATCATT
CAGCAGAAGGAGAAGGGGTTGGAAAACGACCAAAACGAAAGTGTCTTCAGTGGCATCCATTGCTAGCAAAGAAACTTCTTGATTTTTCAG
AAGAGGAAGAAGAGGAAGACGAAGAGGAGGATATTGATAAGGTTCAACTTCTTGGGGCCGATGGCCTAGAGCAAGATGTTGGTGAAACTG
AAGATGATGAATCACCAGAGCAGCGAGCCCGGAGACCAATGAATGCATTTCTTTTATTTTGCAAACGCCATCGCTCTCTTGTACGTCAGG
AACACCCCAGGCTTGATAACCGAGGTGCTACCAAGATACTAGCTGATTGGTGGGCTGTTCTTGATCCAAAGGAAAAGCAGAAATACACAG
ACATGGCCAAGGAGTATAAGGATGCATTTATGAAAGCAAATCCTGGCTACAAATGGTGTCCTACCACAAACAAGCCTGTGAAATCCCCAA
CACCCACTGTCAATCCACGAAAGAAACTTTGGGCCTTCCCATCTGACTCTTCAAGAGACTTGCCAAGCCCCAAGAAAGCAAAGACTGAAG
AAATGCCTCAGCTTAACTTTGGAATGGCTGATCCTACTCAAATGGGAGGCCTGAGTATGCTGCTGTTAGCTGGAGAACATGCTCTTGGCA
CACCAGAGGTATCCTCTGGCACATGCAGGCCTGATGTTTCAGAATCTCCTGAATTACGTCAGAAGTCACCATTGTTTCAGTTTGCCGAGA
TATCTTCAAGTACGTCCCACTCTGATGCTTCTACAAAGCAGTGTCAAACATCTGCCTTGTTTCAGTTTGCAGAGATTTCTTCAAACACTT
CGCAGTTGGGTGGTGCTGAGCCTGTAAAACGCTGTGGAAAGTCTGCACTCTTTCAACTGGCAGAGATGTGCCTGGCATCAGAAGGGATGA
AAATGGAAGAATCAAAGCTAATAAAAGCAAAAGAATCCGATGGTGGAAGAATTAAAGAATTAGAGAAGGGAAAGGAAGAAAAAGAAATTA
AAATGGAGAAAACAGATGAAACTAGGTTACAGAAGGAAGCAGAATTTGAAAAATCGGCTAAGGAAAATTTAAGAGATTCTAAGGAATTGA
GAAATTTTGAGGCATTGCAAATAGATGACATAATGGCTATAAAAATGGAAGATCCCAAAGAAATTAGAAAGGAAGAGTTAGAAGAAGATC
ACAAATGTAGTCATTTTCCTGATTTTTCTTATTCTGCCAGTAGCAAGATAATAATTAGTGATGTTCCCAGTAGAAAGGATCATATGTGCC
ATCCTCATGGAATTATGATCATTGAGGATCCCGCAGCATTAAACAAGCCAGAAAAGCTAAAAAAGAAAAAGAAGAAAAGCAAAATGGATC
GACATGGAAATGATAAATCCACACCCAAGAAGACTTGCAAAAAGAGGCAGTCTTCGGAATCTGACATTGAGAGCGTCATATATACCATTG
AAGCCGTCGCAAAAGGAGACTGGGGCATAGAGAAACTTGGAGATACCCCTCGCAAGAAGGTCCGCACATCCTCAAGTGGCAAGGGAAGCA
TTTTGGATGCCAAGCCACCAAAGAAAAAAGTGAAATCAAGAGAGAAGAAAATGTCAAAGGAGAAATCCTCAGACACCACCAAAGAGTCAA
GACCTCCAGATTTCATTAGTATTTCTGCTAGCAAGAACATTTCTGGTGAGACACCAGAGGGTATAAAAGCAGAACCATTGACCCCTATGG
AAGATGCACTACCACCCAGCCTATCAGGACAGGCCAAGCCTGAGGACAGTGACTGTCACAGAAAAATAGAAACTTGTGGTTCCAGGAAAT
CCGAGAGGTCTTGCAAAGGTGCTCTTTATAAAACCCTGGTGTCTGAGGGCATGCTCACCTCTCTGCGAGCTAATGTTGACAGAGGAAAAC
GAAGCTCAGGAAAAGGAAACTCCTCTGATCATGAAGGGTGTTGGAATGAAGAAAGCTGGACATTTAGTCAGAGTGGGACCAGTGGGAGCA
AGAAGTTCAAGAAGACAAAGCCAAAAGAAGACTGTCTCCTTGGCTCCGCAAAGCTGGATGAAGAATTTGAAAAAAAATTCAACAGCCTCC
CTCAATATAGTCCTGTTACATTTGACCGGAAATGTGTACCTGTCCCAAGAAAAAAGAAGAAGACTGGAAATGTGTCCTCAGAACCGACTA
AAACCAGCAAAGCCATATTTTCAGAAGACAGAAACACCATGGAGCCTGTTCATAAGGTTAAAAATATCCCATCCATTTTCAACACTCCAG
AGCCAACAACAACGCAAGAACCTTTGGTGGGCAGCCAAAAGAGAAAAGCAAGGAAAACCAAGATTACACACCTTGTCAGGACAGCAGATG
GCCGGGTATCACCAGCAGGAGGTACTTTGGGCTTATCCAAATCCCTTGGGCTCATTGAAGGTTATGGTGGGCGGGGTAAAGGGGGCCTTC
CGGCTACTCTTTCCCCGGCTGAAGAAGAAAAGGCTAAGGGACCCCATGAGAAGTATGGCTACAATTCATACCTCAGTGAAAAAATTTCAC
TGGACCGTTCCATTCCGGATTATCGTCCCACCAAGTGTAAGGAGCTCAAGTACTCCAAGGACCTGCCCCAGATATCCATCATATTCATCT
TCGTGAACGAGGCCCTGTCGGTGATCCTGCGGTCCGTGCACAGTGCCGTCAATCACACGCCCACACACCTGCTGAAGGAAATCATTCTGG
TGGATGACAACAGCGACGAAGAGGAGCTGAAGGTCCCCCTAGAGGAGTATGTCCACAAACGCTACCCCGGGCTGGTGAAGGTGGTAAGAA
ATCAGAAGAGGGAAGGCCTGATCCGCGCTCGCATTGAGGGCTGGAAGGTGGCTACCGGGCAGGTCACTGGCTTCTTTGATGCCCACGTGG
AATTCACCGCTGGCTGGGCTGAGCCGGTTCTATCCCGCATCCAGGAAAACCGGAAGCGTGTGATCCTCCCCTCCATTGACAACATCAAAC
AGGACAACTTTGAGGTGCAGCGGTACGAGAACTCGGCCCACGGGTACAGCTGGGAGCTGTGGTGCATGTACATCAGCCCCCCAAAAGACT
GGTGGGACGCCGGAGACCCTTCTCTCCCCATCAGGACCCCAGCCATGATAGGCTGCTCGTTCGTGGTCAACAGGAAGTTCTTCGGTGAAA
TTGGTCTTCTGGATCCTGGCATGGATGTATACGGAGGAGAAAATATTGAACTGGGAATCAAGGTATGGCTCTGTGGGGGCAGCATGGAGG
TCCTTCCTTGCTCACGGGTGGCCCACATTGAGCGGAAGAAGAAGCCATATAATAGCAACATTGGCTTCTACACCAAGAGGAATGCTCTTC
GCGTTGCTGAGGTCTGGATGGACGATTACAAGTCTCATGTGTACATAGCGTGGAACCTGCCGCTGGAGAATCCGGGAATTGACATCGGTG
ATGTCTCCGAAAGAAGAGCATTAAGGAAAAGTTTAAAGTGTAAGAATTTCCAGTGGTACCTGGACCATGTTTACCCAGAAATGAGAAGAT
ACAATAATACCGTTGCTTACGGGGAGCTTCGCAACAACAAGGCAAAAGACGTCTGCTTGGACCAGGGGCCGCTGGAGAACCACACAGCAA
TATTGTATCCGTGCCATGGCTGGGGACCACAGCTTGCCCGCTACACCAAGGAAGGCTTCCTGCACTTGGGTGCCCTGGGGACCACCACAC
TCCTCCCTGACACCCGCTGCCTGGTGGACAACTCCAAGAGTCGGCTGCCCCAGCTCCTGGACTGCGACAAGGTCAAGAGCAGCCTGTACA
AGCGCTGGAACTTCATCCAGAATGGAGCCATCATGAACAAGGGCACGGGACGCTGCCTGGAGGTGGAGAACCGGGGCCTGGCTGGCATCG
ACCTCATCCTCCGCAGCTGCACAGGTCAGAGGTGGACCATTAAGAACTCCATCAAGTAGAGGGAGGGAGCTGGGGCACTGGAGCCTGGCC
CCCAGGACATGGCTGCTCCCCCCAACATCTGGACCAGCTGCCCTGGCGGAGAGACAGCAAGGGGCCGGCAGGTGCTCGATGGGCCCCCCA
GGGCTTCTCCAGGGCAGCACAGGGACCCCGGATGAAGACTCTGTCCCCCCTCAGGCATTCAGCTGCCCACAAGTTTCCTGCACCCTGGAA
AAGCCCCCCACCCTTCCTCTGGGAAACTGACAGCTGTCTTCCACAGCCTCTGATGTGGACCTGGTACTGAGGAGCAAGACTGTCCAGTTC
TCCTCCACATCTCCCATCCCAGAATCAGGATCTGGGACTGGCAGGGTCCCCTCCTGTGTCTCATCTCTTGCAGCAGCAGCTGCTGAACTC
CAGCCATCAACACGGTGGGAGGCAGCGGGGGCTTCAGCCATGTCCTAGCTCCCCGCCCTAAAAGGAGGCAGTGAGGACCAGGCACTATTT
CCTCCGAGGTTACTTCTACCCAGATGACACCTGCCTGTTCACGCCCCAAGGCAGCTACTGCCCCTAACCCTTCCCACCAGGGTAGCTTTG
GGCACTGCAGCTCTGGACTTTTCTGGCCCCTCCTGAGATGACCTGATGGAGCTGATGCTTTCTCTCCTAATCCCTGGGCACTAGGCTCTT
ATCAGTGTGCTTGGGCCAGCTCTCCTGCCTGTGTCTAGAGGAAGCCAGAGACAGAAATAGGCTAAGCCTGCAGTAGGATCTCAGCCACAA
GGGCCCCGCAGGATGGAGCTGGGTCAAGGACCAGGGAGCCCTGACTCCCAGAGGCTGCCACCGGGGAGAAGCAGCGGTCCTCCATCCAGA
ACCTAAGGGCTGAAGCAAAGGCTGCCAGGACCCTTGAAGATGCTTTTGGCTCACCTCATTTCACCCCACGCTCTGCTGGCTGGCAGAGGA
GAAGGCAGTCGTTTCCTCTCTGAAGAGTATTTTTTTCGATTGCCCTCTGGTTAGGGTGCACATATAAATCAGAGTTAATATATGAACGCG
TGTGCATGCACAAGTGTGTGTGTGCCTGCGTGCTGTGCGTGGCAGGGTGTGTGTGTGTGTGTCTGGCTGTGCGTTCCGGAGTGTGTGACG
ATGCTGACCTAGCTGTGTGGCCTTGGGCTTGCTGCTTCATTACTCACCTGGATGGGGACGAGGGATGAGAAGGGTGTGGGTTTGGCCCCA
TGTCACTGGCCGGAAGGATGTGTCTCAGCCCTGCCCTGTGGGGTGCCCCCGATGGGAGGCTGTCCCATCTCCCAGTCCCCATCTCTTTTT
CCCCACACTGTCCCTGGCCAAGCCCTGCCCAGAGCTGAACCCTGTAGCTGCCCCCTTGCCCTGTGTGGGATTCGCAGTGTCTCATTTGGT

>9129_9129_2_BBX-WBSCR17_BBX_chr3_107517567_ENST00000402543_WBSCR17_chr7_70800536_ENST00000333538_length(amino acids)=1319AA_BP=799
MKGSNRNKDHSAEGEGVGKRPKRKCLQWHPLLAKKLLDFSEEEEEEDEEEDIDKVQLLGADGLEQDVGETEDDESPEQRARRPMNAFLLF
CKRHRSLVRQEHPRLDNRGATKILADWWAVLDPKEKQKYTDMAKEYKDAFMKANPGYKWCPTTNKPVKSPTPTVNPRKKLWAFPSDSSRD
LPSPKKAKTEEMPQLNFGMADPTQMGGLSMLLLAGEHALGTPEVSSGTCRPDVSESPELRQKSPLFQFAEISSSTSHSDASTKQCQTSAL
FQFAEISSNTSQLGGAEPVKRCGKSALFQLAEMCLASEGMKMEESKLIKAKESDGGRIKELEKGKEEKEIKMEKTDETRLQKEAEFEKSA
KENLRDSKELRNFEALQIDDIMAIKMEDPKEIRKEELEEDHKCSHFPDFSYSASSKIIISDVPSRKDHMCHPHGIMIIEDPAALNKPEKL
KKKKKKSKMDRHGNDKSTPKKTCKKRQSSESDIESVIYTIEAVAKGDWGIEKLGDTPRKKVRTSSSGKGSILDAKPPKKKVKSREKKMSK
EKSSDTTKESRPPDFISISASKNISGETPEGIKAEPLTPMEDALPPSLSGQAKPEDSDCHRKIETCGSRKSERSCKGALYKTLVSEGMLT
SLRANVDRGKRSSGKGNSSDHEGCWNEESWTFSQSGTSGSKKFKKTKPKEDCLLGSAKLDEEFEKKFNSLPQYSPVTFDRKCVPVPRKKK
KTGNVSSEPTKTSKAIFSEDRNTMEPVHKVKNIPSIFNTPEPTTTQEPLVGSQKRKARKTKITHLVRTADGRVSPAGGTLGLSKSLGLIE
GYGGRGKGGLPATLSPAEEEKAKGPHEKYGYNSYLSEKISLDRSIPDYRPTKCKELKYSKDLPQISIIFIFVNEALSVILRSVHSAVNHT
PTHLLKEIILVDDNSDEEELKVPLEEYVHKRYPGLVKVVRNQKREGLIRARIEGWKVATGQVTGFFDAHVEFTAGWAEPVLSRIQENRKR
VILPSIDNIKQDNFEVQRYENSAHGYSWELWCMYISPPKDWWDAGDPSLPIRTPAMIGCSFVVNRKFFGEIGLLDPGMDVYGGENIELGI
KVWLCGGSMEVLPCSRVAHIERKKKPYNSNIGFYTKRNALRVAEVWMDDYKSHVYIAWNLPLENPGIDIGDVSERRALRKSLKCKNFQWY
LDHVYPEMRRYNNTVAYGELRNNKAKDVCLDQGPLENHTAILYPCHGWGPQLARYTKEGFLHLGALGTTTLLPDTRCLVDNSKSRLPQLL

--------------------------------------------------------------
>9129_9129_3_BBX-WBSCR17_BBX_chr3_107517567_ENST00000406780_WBSCR17_chr7_70800536_ENST00000333538_length(transcript)=6010nt_BP=2998nt
TGCTCAGATCAGCTTCCTGCTTCTCATGAAAGCTGTTCCCCTATAAAGCTGGTCTGCTTTCACTGAAAGAATTATATTCATAAGTCTGAG
GCTGGTTTTGTGGAAGTATTGTTGGTTTGGTTTCCTTTGGGGGATGAAGGAGGAGGAAACAATTTTTTTTAAAAAAAAAGTGGGGGCAGG
CTGAAAGAGCAAAATCATCTTGAATTTTGTTGTCACATCGTGCCGGTGTTATAACCAGCTCTGTAGACTGCCGCACTGAAAACATTTCTG
TGAGAGAATCCTGCTGCATCACAGAAGCTGGAAGTTCTGATGTTCCACTGAAATCACAATGGAAAGTCTTGACTTGACTGGTAAGAGCTG
TTGTGAAGGTACATCTTACTTACTTACCTGGAAGCAGTGAGGCAGTCAAGAATTATGTGCTGTCAGAGCTGGTCTCAGCATGATCAAGGA
AGTGTGATCATTGGATATTTTTTTCTTGTCAATTTTATTATTTTTTAAAGTGTGACTTTTATTGATCTCCATTATCAAGTCACAGTAATG
AAAGGCAGTAATAGAAATAAGGATCATTCAGCAGAAGGAGAAGGGGTTGGAAAACGACCAAAACGAAAGTGTCTTCAGTGGCATCCATTG
CTAGCAAAGAAACTTCTTGATTTTTCAGAAGAGGAAGAAGAGGAAGACGAAGAGGAGGATATTGATAAGGTTCAACTTCTTGGGGCCGAT
GGCCTAGAGCAAGATGTTGGTGAAACTGAAGATGATGAATCACCAGAGCAGCGAGCCCGGAGACCAATGAATGCATTTCTTTTATTTTGC
AAACGCCATCGCTCTCTTGTACGTCAGGAACACCCCAGGCTTGATAACCGAGGTGCTACCAAGATACTAGCTGATTGGTGGGCTGTTCTT
GATCCAAAGGAAAAGCAGAAATACACAGACATGGCCAAGGAGTATAAGGATGCATTTATGAAAGCAAATCCTGGCTACAAATGGTGTCCT
ACCACAAACAAGCCTGTGAAATCCCCAACACCCACTGTCAATCCACGAAAGAAACTTTGGGCCTTCCCATCTGACTCTTCAAGAGACTTG
CCAAGCCCCAAGAAAGCAAAGACTGAAGAAATGCCTCAGCTTAACTTTGGAATGGCTGATCCTACTCAAATGGGAGGCCTGAGTATGCTG
CTGTTAGCTGGAGAACATGCTCTTGGCACACCAGAGGTATCCTCTGGCACATGCAGGCCTGATGTTTCAGAATCTCCTGAATTACGTCAG
AAGTCACCATTGTTTCAGTTTGCCGAGATATCTTCAAGTACGTCCCACTCTGATGCTTCTACAAAGCAGTGTCAAACATCTGCCTTGTTT
CAGTTTGCAGAGATTTCTTCAAACACTTCGCAGTTGGGTGGTGCTGAGCCTGTAAAACGCTGTGGAAAGTCTGCACTCTTTCAACTGGCA
GAGATGTGCCTGGCATCAGAAGGGATGAAAATGGAAGAATCAAAGCTAATAAAAGCAAAAGAATCCGATGGTGGAAGAATTAAAGAATTA
GAGAAGGGAAAGGAAGAAAAAGAAATTAAAATGGAGAAAACAGATGAAACTAGGTTACAGAAGGAAGCAGAATTTGAAAAATCGGCTAAG
GAAAATTTAAGAGATTCTAAGGAATTGAGAAATTTTGAGGCATTGCAAATAGATGACATAATGGCTATAAAAATGGAAGATCCCAAAGAA
ATTAGAAAGGAAGAGTTAGAAGAAGATCACAAATGTAGTCATTTTCCTGATTTTTCTTATTCTGCCAGTAGCAAGATAATAATTAGTGAT
GTTCCCAGTAGAAAGGATCATATGTGCCATCCTCATGGAATTATGATCATTGAGGATCCCGCAGCATTAAACAAGCCAGAAAAGCTAAAA
AAGAAAAAGAAGAAAAGCAAAATGGATCGACATGGAAATGATAAATCCACACCCAAGAAGACTTGCAAAAAGAGGCAGTCTTCGGAATCT
GACATTGAGAGCGTCATATATACCATTGAAGCCGTCGCAAAAGGAGACTGGGGCATAGAGAAACTTGGAGATACCCCTCGCAAGAAGGTC
CGCACATCCTCAAGTGGCAAGGGAAGCATTTTGGATGCCAAGCCACCAAAGAAAAAAGTGAAATCAAGAGAGAAGAAAATGTCAAAGGAG
AAATCCTCAGACACCACCAAAGAGTCAAGACCTCCAGATTTCATTAGTATTTCTGCTAGCAAGAACATTTCTGGTGAGACACCAGAGGGT
ATAAAAGCAGAACCATTGACCCCTATGGAAGATGCACTACCACCCAGCCTATCAGGACAGGCCAAGCCTGAGGACAGTGACTGTCACAGA
AAAATAGAAACTTGTGGTTCCAGGAAATCCGAGAGGTCTTGCAAAGGTGCTCTTTATAAAACCCTGGTGTCTGAGGGCATGCTCACCTCT
CTGCGAGCTAATGTTGACAGAGGAAAACGAAGCTCAGGAAAAGGAAACTCCTCTGATCATGAAGGGTGTTGGAATGAAGAAAGCTGGACA
TTTAGTCAGAGTGGGACCAGTGGGAGCAAGAAGTTCAAGAAGACAAAGCCAAAAGAAGACTGTCTCCTTGGCTCCGCAAAGCTGGATGAA
GAATTTGAAAAAAAATTCAACAGCCTCCCTCAATATAGTCCTGTTACATTTGACCGGAAATGTGTACCTGTCCCAAGAAAAAAGAAGAAG
ACTGGAAATGTGTCCTCAGAACCGACTAAAACCAGCAAAGGAAGTGGGGATAAATGGTCAAACAAGCAACTCTTCTTGGATGCCATTCAC
CCTACAGAAGCCATATTTTCAGAAGACAGAAACACCATGGAGCCTGTTCATAAGGTTAAAAATATCCCATCCATTTTCAACACTCCAGAG
CCAACAACAACGCAAGAACCTTTGGTGGGCAGCCAAAAGAGAAAAGCAAGGAAAACCAAGATTACACACCTTGTCAGGACAGCAGATGGC
CGGGTATCACCAGCAGGAGGTACTTTGGGCTTATCCAAATCCCTTGGGCTCATTGAAGGTTATGGTGGGCGGGGTAAAGGGGGCCTTCCG
GCTACTCTTTCCCCGGCTGAAGAAGAAAAGGCTAAGGGACCCCATGAGAAGTATGGCTACAATTCATACCTCAGTGAAAAAATTTCACTG
GACCGTTCCATTCCGGATTATCGTCCCACCAAGTGTAAGGAGCTCAAGTACTCCAAGGACCTGCCCCAGATATCCATCATATTCATCTTC
GTGAACGAGGCCCTGTCGGTGATCCTGCGGTCCGTGCACAGTGCCGTCAATCACACGCCCACACACCTGCTGAAGGAAATCATTCTGGTG
GATGACAACAGCGACGAAGAGGAGCTGAAGGTCCCCCTAGAGGAGTATGTCCACAAACGCTACCCCGGGCTGGTGAAGGTGGTAAGAAAT
CAGAAGAGGGAAGGCCTGATCCGCGCTCGCATTGAGGGCTGGAAGGTGGCTACCGGGCAGGTCACTGGCTTCTTTGATGCCCACGTGGAA
TTCACCGCTGGCTGGGCTGAGCCGGTTCTATCCCGCATCCAGGAAAACCGGAAGCGTGTGATCCTCCCCTCCATTGACAACATCAAACAG
GACAACTTTGAGGTGCAGCGGTACGAGAACTCGGCCCACGGGTACAGCTGGGAGCTGTGGTGCATGTACATCAGCCCCCCAAAAGACTGG
TGGGACGCCGGAGACCCTTCTCTCCCCATCAGGACCCCAGCCATGATAGGCTGCTCGTTCGTGGTCAACAGGAAGTTCTTCGGTGAAATT
GGTCTTCTGGATCCTGGCATGGATGTATACGGAGGAGAAAATATTGAACTGGGAATCAAGGTATGGCTCTGTGGGGGCAGCATGGAGGTC
CTTCCTTGCTCACGGGTGGCCCACATTGAGCGGAAGAAGAAGCCATATAATAGCAACATTGGCTTCTACACCAAGAGGAATGCTCTTCGC
GTTGCTGAGGTCTGGATGGACGATTACAAGTCTCATGTGTACATAGCGTGGAACCTGCCGCTGGAGAATCCGGGAATTGACATCGGTGAT
GTCTCCGAAAGAAGAGCATTAAGGAAAAGTTTAAAGTGTAAGAATTTCCAGTGGTACCTGGACCATGTTTACCCAGAAATGAGAAGATAC
AATAATACCGTTGCTTACGGGGAGCTTCGCAACAACAAGGCAAAAGACGTCTGCTTGGACCAGGGGCCGCTGGAGAACCACACAGCAATA
TTGTATCCGTGCCATGGCTGGGGACCACAGCTTGCCCGCTACACCAAGGAAGGCTTCCTGCACTTGGGTGCCCTGGGGACCACCACACTC
CTCCCTGACACCCGCTGCCTGGTGGACAACTCCAAGAGTCGGCTGCCCCAGCTCCTGGACTGCGACAAGGTCAAGAGCAGCCTGTACAAG
CGCTGGAACTTCATCCAGAATGGAGCCATCATGAACAAGGGCACGGGACGCTGCCTGGAGGTGGAGAACCGGGGCCTGGCTGGCATCGAC
CTCATCCTCCGCAGCTGCACAGGTCAGAGGTGGACCATTAAGAACTCCATCAAGTAGAGGGAGGGAGCTGGGGCACTGGAGCCTGGCCCC
CAGGACATGGCTGCTCCCCCCAACATCTGGACCAGCTGCCCTGGCGGAGAGACAGCAAGGGGCCGGCAGGTGCTCGATGGGCCCCCCAGG
GCTTCTCCAGGGCAGCACAGGGACCCCGGATGAAGACTCTGTCCCCCCTCAGGCATTCAGCTGCCCACAAGTTTCCTGCACCCTGGAAAA
GCCCCCCACCCTTCCTCTGGGAAACTGACAGCTGTCTTCCACAGCCTCTGATGTGGACCTGGTACTGAGGAGCAAGACTGTCCAGTTCTC
CTCCACATCTCCCATCCCAGAATCAGGATCTGGGACTGGCAGGGTCCCCTCCTGTGTCTCATCTCTTGCAGCAGCAGCTGCTGAACTCCA
GCCATCAACACGGTGGGAGGCAGCGGGGGCTTCAGCCATGTCCTAGCTCCCCGCCCTAAAAGGAGGCAGTGAGGACCAGGCACTATTTCC
TCCGAGGTTACTTCTACCCAGATGACACCTGCCTGTTCACGCCCCAAGGCAGCTACTGCCCCTAACCCTTCCCACCAGGGTAGCTTTGGG
CACTGCAGCTCTGGACTTTTCTGGCCCCTCCTGAGATGACCTGATGGAGCTGATGCTTTCTCTCCTAATCCCTGGGCACTAGGCTCTTAT
CAGTGTGCTTGGGCCAGCTCTCCTGCCTGTGTCTAGAGGAAGCCAGAGACAGAAATAGGCTAAGCCTGCAGTAGGATCTCAGCCACAAGG
GCCCCGCAGGATGGAGCTGGGTCAAGGACCAGGGAGCCCTGACTCCCAGAGGCTGCCACCGGGGAGAAGCAGCGGTCCTCCATCCAGAAC
CTAAGGGCTGAAGCAAAGGCTGCCAGGACCCTTGAAGATGCTTTTGGCTCACCTCATTTCACCCCACGCTCTGCTGGCTGGCAGAGGAGA
AGGCAGTCGTTTCCTCTCTGAAGAGTATTTTTTTCGATTGCCCTCTGGTTAGGGTGCACATATAAATCAGAGTTAATATATGAACGCGTG
TGCATGCACAAGTGTGTGTGTGCCTGCGTGCTGTGCGTGGCAGGGTGTGTGTGTGTGTGTCTGGCTGTGCGTTCCGGAGTGTGTGACGAT
GCTGACCTAGCTGTGTGGCCTTGGGCTTGCTGCTTCATTACTCACCTGGATGGGGACGAGGGATGAGAAGGGTGTGGGTTTGGCCCCATG
TCACTGGCCGGAAGGATGTGTCTCAGCCCTGCCCTGTGGGGTGCCCCCGATGGGAGGCTGTCCCATCTCCCAGTCCCCATCTCTTTTTCC
CCACACTGTCCCTGGCCAAGCCCTGCCCAGAGCTGAACCCTGTAGCTGCCCCCTTGCCCTGTGTGGGATTCGCAGTGTCTCATTTGGTGA

>9129_9129_3_BBX-WBSCR17_BBX_chr3_107517567_ENST00000406780_WBSCR17_chr7_70800536_ENST00000333538_length(amino acids)=1339AA_BP=819
MKGSNRNKDHSAEGEGVGKRPKRKCLQWHPLLAKKLLDFSEEEEEEDEEEDIDKVQLLGADGLEQDVGETEDDESPEQRARRPMNAFLLF
CKRHRSLVRQEHPRLDNRGATKILADWWAVLDPKEKQKYTDMAKEYKDAFMKANPGYKWCPTTNKPVKSPTPTVNPRKKLWAFPSDSSRD
LPSPKKAKTEEMPQLNFGMADPTQMGGLSMLLLAGEHALGTPEVSSGTCRPDVSESPELRQKSPLFQFAEISSSTSHSDASTKQCQTSAL
FQFAEISSNTSQLGGAEPVKRCGKSALFQLAEMCLASEGMKMEESKLIKAKESDGGRIKELEKGKEEKEIKMEKTDETRLQKEAEFEKSA
KENLRDSKELRNFEALQIDDIMAIKMEDPKEIRKEELEEDHKCSHFPDFSYSASSKIIISDVPSRKDHMCHPHGIMIIEDPAALNKPEKL
KKKKKKSKMDRHGNDKSTPKKTCKKRQSSESDIESVIYTIEAVAKGDWGIEKLGDTPRKKVRTSSSGKGSILDAKPPKKKVKSREKKMSK
EKSSDTTKESRPPDFISISASKNISGETPEGIKAEPLTPMEDALPPSLSGQAKPEDSDCHRKIETCGSRKSERSCKGALYKTLVSEGMLT
SLRANVDRGKRSSGKGNSSDHEGCWNEESWTFSQSGTSGSKKFKKTKPKEDCLLGSAKLDEEFEKKFNSLPQYSPVTFDRKCVPVPRKKK
KTGNVSSEPTKTSKGSGDKWSNKQLFLDAIHPTEAIFSEDRNTMEPVHKVKNIPSIFNTPEPTTTQEPLVGSQKRKARKTKITHLVRTAD
GRVSPAGGTLGLSKSLGLIEGYGGRGKGGLPATLSPAEEEKAKGPHEKYGYNSYLSEKISLDRSIPDYRPTKCKELKYSKDLPQISIIFI
FVNEALSVILRSVHSAVNHTPTHLLKEIILVDDNSDEEELKVPLEEYVHKRYPGLVKVVRNQKREGLIRARIEGWKVATGQVTGFFDAHV
EFTAGWAEPVLSRIQENRKRVILPSIDNIKQDNFEVQRYENSAHGYSWELWCMYISPPKDWWDAGDPSLPIRTPAMIGCSFVVNRKFFGE
IGLLDPGMDVYGGENIELGIKVWLCGGSMEVLPCSRVAHIERKKKPYNSNIGFYTKRNALRVAEVWMDDYKSHVYIAWNLPLENPGIDIG
DVSERRALRKSLKCKNFQWYLDHVYPEMRRYNNTVAYGELRNNKAKDVCLDQGPLENHTAILYPCHGWGPQLARYTKEGFLHLGALGTTT

--------------------------------------------------------------
>9129_9129_4_BBX-WBSCR17_BBX_chr3_107517567_ENST00000415149_WBSCR17_chr7_70800536_ENST00000333538_length(transcript)=5800nt_BP=2788nt
AAAATGAGTGTTTTCAGTCTCTCCGGGTTGCATGTACTGTATGTGGAGCAGTGTACAGTGAAGCGGAGGCAGAGCGGCTCCGCGAGCTTC
TCTCCACTTTCCCATAGAGAAACCCTGACTGGCCGCTGAGGGCTAGCTACACACACGCCCTCACGCCCGGCGAGCCCGCGAGGTCACTAT
CATATGACAAAGGCTTTGCCGCAGTTCATCTTCCTCCCTGTGTACTTTCCATTTGCCTTCCTGGAATCCTGCTGCATCACAGAAGCTGGA
AGTTCTGATGTTCCACTGAAATCACAATGGAAAGTCTTGACTTGACTGGTCACAGTAATGAAAGGCAGTAATAGAAATAAGGATCATTCA
GCAGAAGGAGAAGGGGTTGGAAAACGACCAAAACGAAAGTGTCTTCAGTGGCATCCATTGCTAGCAAAGAAACTTCTTGATTTTTCAGAA
GAGGAAGAAGAGGAAGACGAAGAGGAGGATATTGATAAGGTTCAACTTCTTGGGGCCGATGGCCTAGAGCAAGATGTTGGTGAAACTGAA
GATGATGAATCACCAGAGCAGCGAGCCCGGAGACCAATGAATGCATTTCTTTTATTTTGCAAACGCCATCGCTCTCTTGTACGTCAGGAA
CACCCCAGGCTTGATAACCGAGGTGCTACCAAGATACTAGCTGATTGGTGGGCTGTTCTTGATCCAAAGGAAAAGCAGAAATACACAGAC
ATGGCCAAGGAGTATAAGGATGCATTTATGAAAGCAAATCCTGGCTACAAATGGTGTCCTACCACAAACAAGCCTGTGAAATCCCCAACA
CCCACTGTCAATCCACGAAAGAAACTTTGGGCCTTCCCATCTGACTCTTCAAGAGACTTGCCAAGCCCCAAGAAAGCAAAGACTGAAGAA
ATGCCTCAGCTTAACTTTGGAATGGCTGATCCTACTCAAATGGGAGGCCTGAGTATGCTGCTGTTAGCTGGAGAACATGCTCTTGGCACA
CCAGAGGTATCCTCTGGCACATGCAGGCCTGATGTTTCAGAATCTCCTGAATTACGTCAGAAGTCACCATTGTTTCAGTTTGCCGAGATA
TCTTCAAGTACGTCCCACTCTGATGCTTCTACAAAGCAGTGTCAAACATCTGCCTTGTTTCAGTTTGCAGAGATTTCTTCAAACACTTCG
CAGTTGGGTGGTGCTGAGCCTGTAAAACGCTGTGGAAAGTCTGCACTCTTTCAACTGGCAGAGATGTGCCTGGCATCAGAAGGGATGAAA
ATGGAAGAATCAAAGCTAATAAAAGCAAAAGAATCCGATGGTGGAAGAATTAAAGAATTAGAGAAGGGAAAGGAAGAAAAAGAAATTAAA
ATGGAGAAAACAGATGAAACTAGGTTACAGAAGGAAGCAGAATTTGAAAAATCGGCTAAGGAAAATTTAAGAGATTCTAAGGAATTGAGA
AATTTTGAGGCATTGCAAATAGATGACATAATGGCTATAAAAATGGAAGATCCCAAAGAAATTAGAAAGGAAGAGTTAGAAGAAGATCAC
AAATGTAGTCATTTTCCTGATTTTTCTTATTCTGCCAGTAGCAAGATAATAATTAGTGATGTTCCCAGTAGAAAGGATCATATGTGCCAT
CCTCATGGAATTATGATCATTGAGGATCCCGCAGCATTAAACAAGCCAGAAAAGCTAAAAAAGAAAAAGAAGAAAAGCAAAATGGATCGA
CATGGAAATGATAAATCCACACCCAAGAAGACTTGCAAAAAGAGGCAGTCTTCGGAATCTGACATTGAGAGCGTCATATATACCATTGAA
GCCGTCGCAAAAGGAGACTGGGGCATAGAGAAACTTGGAGATACCCCTCGCAAGAAGGTCCGCACATCCTCAAGTGGCAAGGGAAGCATT
TTGGATGCCAAGCCACCAAAGAAAAAAGTGAAATCAAGAGAGAAGAAAATGTCAAAGGAGAAATCCTCAGACACCACCAAAGAGTCAAGA
CCTCCAGATTTCATTAGTATTTCTGCTAGCAAGAACATTTCTGGTGAGACACCAGAGGGTATAAAAGCAGAACCATTGACCCCTATGGAA
GATGCACTACCACCCAGCCTATCAGGACAGGCCAAGCCTGAGGACAGTGACTGTCACAGAAAAATAGAAACTTGTGGTTCCAGGAAATCC
GAGAGGTCTTGCAAAGGTGCTCTTTATAAAACCCTGGTGTCTGAGGGCATGCTCACCTCTCTGCGAGCTAATGTTGACAGAGGAAAACGA
AGCTCAGGAAAAGGAAACTCCTCTGATCATGAAGGGTGTTGGAATGAAGAAAGCTGGACATTTAGTCAGAGTGGGACCAGTGGGAGCAAG
AAGTTCAAGAAGACAAAGCCAAAAGAAGACTGTCTCCTTGGCTCCGCAAAGCTGGATGAAGAATTTGAAAAAAAATTCAACAGCCTCCCT
CAATATAGTCCTGTTACATTTGACCGGAAATGTGTACCTGTCCCAAGAAAAAAGAAGAAGACTGGAAATGTGTCCTCAGAACCGACTAAA
ACCAGCAAAGGAAGTGGGGATAAATGGTCAAACAAGCAACTCTTCTTGGATGCCATTCACCCTACAGAAGCCATATTTTCAGAAGACAGA
AACACCATGGAGCCTGTTCATAAGGTTAAAAATATCCCATCCATTTTCAACACTCCAGAGCCAACAACAACGCAAGAACCTTTGGTGGGC
AGCCAAAAGAGAAAAGCAAGGAAAACCAAGATTACACACCTTGTCAGGACAGCAGATGGCCGGGTATCACCAGCAGGAGGTACTTTGGGC
TTATCCAAATCCCTTGGGCTCATTGAAGGTTATGGTGGGCGGGGTAAAGGGGGCCTTCCGGCTACTCTTTCCCCGGCTGAAGAAGAAAAG
GCTAAGGGACCCCATGAGAAGTATGGCTACAATTCATACCTCAGTGAAAAAATTTCACTGGACCGTTCCATTCCGGATTATCGTCCCACC
AAGTGTAAGGAGCTCAAGTACTCCAAGGACCTGCCCCAGATATCCATCATATTCATCTTCGTGAACGAGGCCCTGTCGGTGATCCTGCGG
TCCGTGCACAGTGCCGTCAATCACACGCCCACACACCTGCTGAAGGAAATCATTCTGGTGGATGACAACAGCGACGAAGAGGAGCTGAAG
GTCCCCCTAGAGGAGTATGTCCACAAACGCTACCCCGGGCTGGTGAAGGTGGTAAGAAATCAGAAGAGGGAAGGCCTGATCCGCGCTCGC
ATTGAGGGCTGGAAGGTGGCTACCGGGCAGGTCACTGGCTTCTTTGATGCCCACGTGGAATTCACCGCTGGCTGGGCTGAGCCGGTTCTA
TCCCGCATCCAGGAAAACCGGAAGCGTGTGATCCTCCCCTCCATTGACAACATCAAACAGGACAACTTTGAGGTGCAGCGGTACGAGAAC
TCGGCCCACGGGTACAGCTGGGAGCTGTGGTGCATGTACATCAGCCCCCCAAAAGACTGGTGGGACGCCGGAGACCCTTCTCTCCCCATC
AGGACCCCAGCCATGATAGGCTGCTCGTTCGTGGTCAACAGGAAGTTCTTCGGTGAAATTGGTCTTCTGGATCCTGGCATGGATGTATAC
GGAGGAGAAAATATTGAACTGGGAATCAAGGTATGGCTCTGTGGGGGCAGCATGGAGGTCCTTCCTTGCTCACGGGTGGCCCACATTGAG
CGGAAGAAGAAGCCATATAATAGCAACATTGGCTTCTACACCAAGAGGAATGCTCTTCGCGTTGCTGAGGTCTGGATGGACGATTACAAG
TCTCATGTGTACATAGCGTGGAACCTGCCGCTGGAGAATCCGGGAATTGACATCGGTGATGTCTCCGAAAGAAGAGCATTAAGGAAAAGT
TTAAAGTGTAAGAATTTCCAGTGGTACCTGGACCATGTTTACCCAGAAATGAGAAGATACAATAATACCGTTGCTTACGGGGAGCTTCGC
AACAACAAGGCAAAAGACGTCTGCTTGGACCAGGGGCCGCTGGAGAACCACACAGCAATATTGTATCCGTGCCATGGCTGGGGACCACAG
CTTGCCCGCTACACCAAGGAAGGCTTCCTGCACTTGGGTGCCCTGGGGACCACCACACTCCTCCCTGACACCCGCTGCCTGGTGGACAAC
TCCAAGAGTCGGCTGCCCCAGCTCCTGGACTGCGACAAGGTCAAGAGCAGCCTGTACAAGCGCTGGAACTTCATCCAGAATGGAGCCATC
ATGAACAAGGGCACGGGACGCTGCCTGGAGGTGGAGAACCGGGGCCTGGCTGGCATCGACCTCATCCTCCGCAGCTGCACAGGTCAGAGG
TGGACCATTAAGAACTCCATCAAGTAGAGGGAGGGAGCTGGGGCACTGGAGCCTGGCCCCCAGGACATGGCTGCTCCCCCCAACATCTGG
ACCAGCTGCCCTGGCGGAGAGACAGCAAGGGGCCGGCAGGTGCTCGATGGGCCCCCCAGGGCTTCTCCAGGGCAGCACAGGGACCCCGGA
TGAAGACTCTGTCCCCCCTCAGGCATTCAGCTGCCCACAAGTTTCCTGCACCCTGGAAAAGCCCCCCACCCTTCCTCTGGGAAACTGACA
GCTGTCTTCCACAGCCTCTGATGTGGACCTGGTACTGAGGAGCAAGACTGTCCAGTTCTCCTCCACATCTCCCATCCCAGAATCAGGATC
TGGGACTGGCAGGGTCCCCTCCTGTGTCTCATCTCTTGCAGCAGCAGCTGCTGAACTCCAGCCATCAACACGGTGGGAGGCAGCGGGGGC
TTCAGCCATGTCCTAGCTCCCCGCCCTAAAAGGAGGCAGTGAGGACCAGGCACTATTTCCTCCGAGGTTACTTCTACCCAGATGACACCT
GCCTGTTCACGCCCCAAGGCAGCTACTGCCCCTAACCCTTCCCACCAGGGTAGCTTTGGGCACTGCAGCTCTGGACTTTTCTGGCCCCTC
CTGAGATGACCTGATGGAGCTGATGCTTTCTCTCCTAATCCCTGGGCACTAGGCTCTTATCAGTGTGCTTGGGCCAGCTCTCCTGCCTGT
GTCTAGAGGAAGCCAGAGACAGAAATAGGCTAAGCCTGCAGTAGGATCTCAGCCACAAGGGCCCCGCAGGATGGAGCTGGGTCAAGGACC
AGGGAGCCCTGACTCCCAGAGGCTGCCACCGGGGAGAAGCAGCGGTCCTCCATCCAGAACCTAAGGGCTGAAGCAAAGGCTGCCAGGACC
CTTGAAGATGCTTTTGGCTCACCTCATTTCACCCCACGCTCTGCTGGCTGGCAGAGGAGAAGGCAGTCGTTTCCTCTCTGAAGAGTATTT
TTTTCGATTGCCCTCTGGTTAGGGTGCACATATAAATCAGAGTTAATATATGAACGCGTGTGCATGCACAAGTGTGTGTGTGCCTGCGTG
CTGTGCGTGGCAGGGTGTGTGTGTGTGTGTCTGGCTGTGCGTTCCGGAGTGTGTGACGATGCTGACCTAGCTGTGTGGCCTTGGGCTTGC
TGCTTCATTACTCACCTGGATGGGGACGAGGGATGAGAAGGGTGTGGGTTTGGCCCCATGTCACTGGCCGGAAGGATGTGTCTCAGCCCT
GCCCTGTGGGGTGCCCCCGATGGGAGGCTGTCCCATCTCCCAGTCCCCATCTCTTTTTCCCCACACTGTCCCTGGCCAAGCCCTGCCCAG
AGCTGAACCCTGTAGCTGCCCCCTTGCCCTGTGTGGGATTCGCAGTGTCTCATTTGGTGACGTCTTACTGGTGATCATCTCCTCACCCCA

>9129_9129_4_BBX-WBSCR17_BBX_chr3_107517567_ENST00000415149_WBSCR17_chr7_70800536_ENST00000333538_length(amino acids)=1343AA_BP=823
MVTVMKGSNRNKDHSAEGEGVGKRPKRKCLQWHPLLAKKLLDFSEEEEEEDEEEDIDKVQLLGADGLEQDVGETEDDESPEQRARRPMNA
FLLFCKRHRSLVRQEHPRLDNRGATKILADWWAVLDPKEKQKYTDMAKEYKDAFMKANPGYKWCPTTNKPVKSPTPTVNPRKKLWAFPSD
SSRDLPSPKKAKTEEMPQLNFGMADPTQMGGLSMLLLAGEHALGTPEVSSGTCRPDVSESPELRQKSPLFQFAEISSSTSHSDASTKQCQ
TSALFQFAEISSNTSQLGGAEPVKRCGKSALFQLAEMCLASEGMKMEESKLIKAKESDGGRIKELEKGKEEKEIKMEKTDETRLQKEAEF
EKSAKENLRDSKELRNFEALQIDDIMAIKMEDPKEIRKEELEEDHKCSHFPDFSYSASSKIIISDVPSRKDHMCHPHGIMIIEDPAALNK
PEKLKKKKKKSKMDRHGNDKSTPKKTCKKRQSSESDIESVIYTIEAVAKGDWGIEKLGDTPRKKVRTSSSGKGSILDAKPPKKKVKSREK
KMSKEKSSDTTKESRPPDFISISASKNISGETPEGIKAEPLTPMEDALPPSLSGQAKPEDSDCHRKIETCGSRKSERSCKGALYKTLVSE
GMLTSLRANVDRGKRSSGKGNSSDHEGCWNEESWTFSQSGTSGSKKFKKTKPKEDCLLGSAKLDEEFEKKFNSLPQYSPVTFDRKCVPVP
RKKKKTGNVSSEPTKTSKGSGDKWSNKQLFLDAIHPTEAIFSEDRNTMEPVHKVKNIPSIFNTPEPTTTQEPLVGSQKRKARKTKITHLV
RTADGRVSPAGGTLGLSKSLGLIEGYGGRGKGGLPATLSPAEEEKAKGPHEKYGYNSYLSEKISLDRSIPDYRPTKCKELKYSKDLPQIS
IIFIFVNEALSVILRSVHSAVNHTPTHLLKEIILVDDNSDEEELKVPLEEYVHKRYPGLVKVVRNQKREGLIRARIEGWKVATGQVTGFF
DAHVEFTAGWAEPVLSRIQENRKRVILPSIDNIKQDNFEVQRYENSAHGYSWELWCMYISPPKDWWDAGDPSLPIRTPAMIGCSFVVNRK
FFGEIGLLDPGMDVYGGENIELGIKVWLCGGSMEVLPCSRVAHIERKKKPYNSNIGFYTKRNALRVAEVWMDDYKSHVYIAWNLPLENPG
IDIGDVSERRALRKSLKCKNFQWYLDHVYPEMRRYNNTVAYGELRNNKAKDVCLDQGPLENHTAILYPCHGWGPQLARYTKEGFLHLGAL

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Fusion Gene PPI Analysis for BBX-WBSCR17


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for BBX-WBSCR17


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for BBX-WBSCR17


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource