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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:CCDC47-GH1 (FusionGDB2 ID:HG57003TG2688)

Fusion Gene Summary for CCDC47-GH1

check button Fusion gene summary
Fusion gene informationFusion gene name: CCDC47-GH1
Fusion gene ID: hg57003tg2688
HgeneTgene
Gene symbol

CCDC47

GH1

Gene ID

57003

2688

Gene namecoiled-coil domain containing 47growth hormone 1
SynonymsGK001|MSTP041|THNSGH|GH-N|GHB5|GHN|IGHD1A|IGHD1B|IGHD2|hGH-N
Cytomap('CCDC47')('GH1')

17q23.3

17q23.3

Type of geneprotein-codingprotein-coding
Descriptioncoiled-coil domain-containing protein 47Caluminsomatotropingrowth hormone B5pituitary growth hormone
Modification date2020031320200322
UniProtAcc.

P01241

Ensembl transtripts involved in fusion geneENST00000225726, ENST00000403162, 
ENST00000582252, 
Fusion gene scores* DoF score6 X 5 X 5=1503 X 2 X 3=18
# samples 63
** MAII scorelog2(6/150*10)=-1.32192809488736
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(3/18*10)=0.736965594166206
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: CCDC47 [Title/Abstract] AND GH1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCCDC47(61838274)-GH1(61995866), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneGH1

GO:0002092

positive regulation of receptor internalization

9360546

TgeneGH1

GO:0010536

positive regulation of activation of Janus kinase activity

8063815|12552091

TgeneGH1

GO:0010828

positive regulation of glucose transmembrane transport

9144201

TgeneGH1

GO:0014068

positive regulation of phosphatidylinositol 3-kinase signaling

7782332

TgeneGH1

GO:0032355

response to estradiol

12552091

TgeneGH1

GO:0040018

positive regulation of multicellular organism growth

7565946|20110402

TgeneGH1

GO:0042531

positive regulation of tyrosine phosphorylation of STAT protein

8923468|12552091

TgeneGH1

GO:0043568

positive regulation of insulin-like growth factor receptor signaling pathway

7565946

TgeneGH1

GO:0046427

positive regulation of JAK-STAT cascade

8063815|8923468

TgeneGH1

GO:0050731

positive regulation of peptidyl-tyrosine phosphorylation

7782332

TgeneGH1

GO:0060396

growth hormone receptor signaling pathway

8063815

TgeneGH1

GO:0070977

bone maturation

20110402


check buttonFusion gene breakpoints across CCDC47 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across GH1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-A1-A0SN-01ACCDC47chr17

61838274

-GH1chr17

61995866

-


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Fusion Gene ORF analysis for CCDC47-GH1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000225726ENST00000323322CCDC47chr17

61838274

-GH1chr17

61995866

-
In-frameENST00000225726ENST00000342364CCDC47chr17

61838274

-GH1chr17

61995866

-
In-frameENST00000225726ENST00000351388CCDC47chr17

61838274

-GH1chr17

61995866

-
In-frameENST00000225726ENST00000458650CCDC47chr17

61838274

-GH1chr17

61995866

-
In-frameENST00000403162ENST00000323322CCDC47chr17

61838274

-GH1chr17

61995866

-
In-frameENST00000403162ENST00000342364CCDC47chr17

61838274

-GH1chr17

61995866

-
In-frameENST00000403162ENST00000351388CCDC47chr17

61838274

-GH1chr17

61995866

-
In-frameENST00000403162ENST00000458650CCDC47chr17

61838274

-GH1chr17

61995866

-
In-frameENST00000582252ENST00000323322CCDC47chr17

61838274

-GH1chr17

61995866

-
In-frameENST00000582252ENST00000342364CCDC47chr17

61838274

-GH1chr17

61995866

-
In-frameENST00000582252ENST00000351388CCDC47chr17

61838274

-GH1chr17

61995866

-
In-frameENST00000582252ENST00000458650CCDC47chr17

61838274

-GH1chr17

61995866

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000225726CCDC47chr1761838274-ENST00000351388GH1chr1761995866-175111183831285300
ENST00000225726CCDC47chr1761838274-ENST00000458650GH1chr1761995866-182311183831360325
ENST00000225726CCDC47chr1761838274-ENST00000323322GH1chr1761995866-186811183831405340
ENST00000225726CCDC47chr1761838274-ENST00000342364GH1chr1761995866-147711183831474364
ENST00000403162CCDC47chr1761838274-ENST00000351388GH1chr1761995866-163310002651167300
ENST00000403162CCDC47chr1761838274-ENST00000458650GH1chr1761995866-170510002651242325
ENST00000403162CCDC47chr1761838274-ENST00000323322GH1chr1761995866-175010002651287340
ENST00000403162CCDC47chr1761838274-ENST00000342364GH1chr1761995866-135910002651356364
ENST00000582252CCDC47chr1761838274-ENST00000351388GH1chr1761995866-15469131781080300
ENST00000582252CCDC47chr1761838274-ENST00000458650GH1chr1761995866-16189131781155325
ENST00000582252CCDC47chr1761838274-ENST00000323322GH1chr1761995866-16639131781200340
ENST00000582252CCDC47chr1761838274-ENST00000342364GH1chr1761995866-12729131781269364

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000225726ENST00000351388CCDC47chr1761838274-GH1chr1761995866-0.0015288340.9984712
ENST00000225726ENST00000458650CCDC47chr1761838274-GH1chr1761995866-0.0014207660.99857926
ENST00000225726ENST00000323322CCDC47chr1761838274-GH1chr1761995866-0.0013639250.99863607
ENST00000225726ENST00000342364CCDC47chr1761838274-GH1chr1761995866-0.065399480.93460053
ENST00000403162ENST00000351388CCDC47chr1761838274-GH1chr1761995866-0.0013290330.99867094
ENST00000403162ENST00000458650CCDC47chr1761838274-GH1chr1761995866-0.0013709610.9986291
ENST00000403162ENST00000323322CCDC47chr1761838274-GH1chr1761995866-0.001339330.9986607
ENST00000403162ENST00000342364CCDC47chr1761838274-GH1chr1761995866-0.040533740.9594663
ENST00000582252ENST00000351388CCDC47chr1761838274-GH1chr1761995866-0.0012582240.9987418
ENST00000582252ENST00000458650CCDC47chr1761838274-GH1chr1761995866-0.0011750120.998825
ENST00000582252ENST00000323322CCDC47chr1761838274-GH1chr1761995866-0.0011261870.9988738
ENST00000582252ENST00000342364CCDC47chr1761838274-GH1chr1761995866-0.051904370.9480956

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Fusion Genomic Features for CCDC47-GH1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for CCDC47-GH1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr17:61838274/chr17:61995866)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.GH1

P01241

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCCDC47chr17:61838274chr17:61995866ENST00000225726-613136_155245484.0TransmembraneHelical
HgeneCCDC47chr17:61838274chr17:61995866ENST00000403162-714136_155245484.0TransmembraneHelical
HgeneCCDC47chr17:61838274chr17:61995866ENST00000582252-612136_155245481.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCCDC47chr17:61838274chr17:61995866ENST00000225726-613450_483245484.0Coiled coilOntology_term=ECO:0000255
HgeneCCDC47chr17:61838274chr17:61995866ENST00000403162-714450_483245484.0Coiled coilOntology_term=ECO:0000255
HgeneCCDC47chr17:61838274chr17:61995866ENST00000582252-612450_483245481.0Coiled coilOntology_term=ECO:0000255


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Fusion Gene Sequence for CCDC47-GH1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>13814_13814_1_CCDC47-GH1_CCDC47_chr17_61838274_ENST00000225726_GH1_chr17_61995866_ENST00000323322_length(transcript)=1868nt_BP=1118nt
GTAGGAGGATTGGGATAGGCGAGGGCAGTTCCGGCCCAGGGGCGGGGATTATGTAATTTTCCCAAAAGCCCCACCTCGCCTCAGCCGGGC
GGGAGAGAGGGAGGTCTCGCGCTTTCCCCGGGGTTGCGTCCCGCCCCGCAGGCTGCGCGCAGGCGCTGACGAGCCGCTCGCATTCTACGT
AACGGACGGCGGAGGCTACGTGAAGAGAGGCGCGGCGTGACTGAGCTACGGTTCTGGCTGCGTCCTAGAGGCATCCGGGGCAGTAAAACC
GCTGCGATCGCGGAGGCGGCGGCCAGGCCGAGAGGCAGGCCGGGCAGGGGTGTCGGACGCAGGGCGCTGGGCCGGGTTTCGGCTTCGGCC
ACAGCTTTTTTTCTCAAGGTGCAATGAAAGCCTTCCACACTTTCTGTGTTGTCCTTCTGGTGTTTGGGAGTGTCTCTGAAGCCAAGTTTG
ATGATTTTGAGGATGAGGAGGACATAGTAGAGTATGATGATAATGACTTCGCTGAATTTGAGGATGTCATGGAAGACTCTGTTACTGAAT
CTCCTCAACGGGTCATAATCACTGAAGATGATGAAGATGAGACCACTGTGGAGTTGGAAGGGCAGGATGAAAACCAAGAAGGAGATTTTG
AAGATGCAGATACCCAGGAGGGAGATACTGAGAGTGAACCATATGATGATGAAGAATTTGAAGGTTATGAAGACAAACCAGATACTTCTT
CTAGCAAAAATAAAGACCCAATAACGATTGTTGATGTTCCTGCACACCTCCAGAACAGCTGGGAGAGTTATTATCTAGAAATTTTGATGG
TGACTGGTCTGCTTGCTTATATCATGAATTACATCATTGGGAAGAATAAAAACAGTCGCCTTGCACAGGCCTGGTTTAACACTCATAGGG
AGCTTTTGGAGAGCAACTTTACTTTAGTGGGGGATGATGGAACTAACAAAGAAGCCACAAGCACAGGAAAGTTGAACCAGGAGAATGAGC
ACATCTATAACCTGTGGTGTTCTGGTCGAGTGTGCTGTGAGGGCATGCTTATCCAGCTGAGGTTCCTCAAGAGACAAGACTTACTGAATG
TCCTGGCCCGGATGATGAGGCCAGTGAGTGATCAAGTGGCTCCCGGACGTCCCTGCTCCTGGCTTTTGGCCTGCTCTGCCTGCCCTGGCT
TCAAGAGGGCAGTGCCTTCCCAACCATTCCCTTATCCAGGCTTTTTGACAACGCTATGCTCCGCGCCCATCGTCTGCACCAGCTGGCCTT
TGACACCTACCAGGAGTTTGAAGAAGCCTATATCCCAAAGGAACAGAAGTATTCATTCCTGCAGAACCCCCAGACCTCCCTCTGTTTCTC
AGAGTCTATTCCGACACCCTCCAACAGGGAGGAAACACAACAGAAATCCAACCTAGAGCTGCTCCGCATCTCCCTGCTGCTCATCCAGTC
GTGGCTGGAGCCCGTGCAGTTCCTCAGGAGTGTCTTCGCCAACAGCCTGGTGTACGGCGCCTCTGACAGCAACGTCTATGACCTCCTAAA
GGACCTAGAGGAAGGCATCCAAACGCTGATGGGGAGGCTGGAAGATGGCAGCCCCCGGACTGGGCAGATCTTCAAGCAGACCTACAGCAA
GTTCGACACAAACTCACACAACGATGACGCACTACTCAAGAACTACGGGCTGCTCTACTGCTTCAGGAAGGACATGGACAAGGTCGAGAC
ATTCCTGCGCATCGTGCAGTGCCGCTCTGTGGAGGGCAGCTGTGGCTTCTAGCTGCCCGGGTGGCATCCCTGTGACCCCTCCCCAGTGCC

>13814_13814_1_CCDC47-GH1_CCDC47_chr17_61838274_ENST00000225726_GH1_chr17_61995866_ENST00000323322_length(amino acids)=340AA_BP=245
MKAFHTFCVVLLVFGSVSEAKFDDFEDEEDIVEYDDNDFAEFEDVMEDSVTESPQRVIITEDDEDETTVELEGQDENQEGDFEDADTQEG
DTESEPYDDEEFEGYEDKPDTSSSKNKDPITIVDVPAHLQNSWESYYLEILMVTGLLAYIMNYIIGKNKNSRLAQAWFNTHRELLESNFT
LVGDDGTNKEATSTGKLNQENEHIYNLWCSGRVCCEGMLIQLRFLKRQDLLNVLARMMRPVSDQVAPGRPCSWLLACSACPGFKRAVPSQ

--------------------------------------------------------------
>13814_13814_2_CCDC47-GH1_CCDC47_chr17_61838274_ENST00000225726_GH1_chr17_61995866_ENST00000342364_length(transcript)=1477nt_BP=1118nt
GTAGGAGGATTGGGATAGGCGAGGGCAGTTCCGGCCCAGGGGCGGGGATTATGTAATTTTCCCAAAAGCCCCACCTCGCCTCAGCCGGGC
GGGAGAGAGGGAGGTCTCGCGCTTTCCCCGGGGTTGCGTCCCGCCCCGCAGGCTGCGCGCAGGCGCTGACGAGCCGCTCGCATTCTACGT
AACGGACGGCGGAGGCTACGTGAAGAGAGGCGCGGCGTGACTGAGCTACGGTTCTGGCTGCGTCCTAGAGGCATCCGGGGCAGTAAAACC
GCTGCGATCGCGGAGGCGGCGGCCAGGCCGAGAGGCAGGCCGGGCAGGGGTGTCGGACGCAGGGCGCTGGGCCGGGTTTCGGCTTCGGCC
ACAGCTTTTTTTCTCAAGGTGCAATGAAAGCCTTCCACACTTTCTGTGTTGTCCTTCTGGTGTTTGGGAGTGTCTCTGAAGCCAAGTTTG
ATGATTTTGAGGATGAGGAGGACATAGTAGAGTATGATGATAATGACTTCGCTGAATTTGAGGATGTCATGGAAGACTCTGTTACTGAAT
CTCCTCAACGGGTCATAATCACTGAAGATGATGAAGATGAGACCACTGTGGAGTTGGAAGGGCAGGATGAAAACCAAGAAGGAGATTTTG
AAGATGCAGATACCCAGGAGGGAGATACTGAGAGTGAACCATATGATGATGAAGAATTTGAAGGTTATGAAGACAAACCAGATACTTCTT
CTAGCAAAAATAAAGACCCAATAACGATTGTTGATGTTCCTGCACACCTCCAGAACAGCTGGGAGAGTTATTATCTAGAAATTTTGATGG
TGACTGGTCTGCTTGCTTATATCATGAATTACATCATTGGGAAGAATAAAAACAGTCGCCTTGCACAGGCCTGGTTTAACACTCATAGGG
AGCTTTTGGAGAGCAACTTTACTTTAGTGGGGGATGATGGAACTAACAAAGAAGCCACAAGCACAGGAAAGTTGAACCAGGAGAATGAGC
ACATCTATAACCTGTGGTGTTCTGGTCGAGTGTGCTGTGAGGGCATGCTTATCCAGCTGAGGTTCCTCAAGAGACAAGACTTACTGAATG
TCCTGGCCCGGATGATGAGGCCAGTGAGTGATCAAGTGGCTCCCGGACGTCCCTGCTCCTGGCTTTTGGCCTGCTCTGCCTGCCCTGGCT
TCAAGAGGGCAGTGCCTTCCCAACCATTCCCTTATCCAGGCTTTTTGACAACGCTATGCTCCGCGCCCATCGTCTGCACCAGCTGGCCTT
TGACACCTACCAGGAGTTTAGGCTGGAAGATGGCAGCCCCCGGACTGGGCAGATCTTCAAGCAGACCTACAGCAAGTTCGACACAAACTC
ACACAACGATGACGCACTACTCAAGAACTACGGGCTGCTCTACTGCTTCAGGAAGGACATGGACAAGGTCGAGACATTCCTGCGCATCGT

>13814_13814_2_CCDC47-GH1_CCDC47_chr17_61838274_ENST00000225726_GH1_chr17_61995866_ENST00000342364_length(amino acids)=364AA_BP=245
MKAFHTFCVVLLVFGSVSEAKFDDFEDEEDIVEYDDNDFAEFEDVMEDSVTESPQRVIITEDDEDETTVELEGQDENQEGDFEDADTQEG
DTESEPYDDEEFEGYEDKPDTSSSKNKDPITIVDVPAHLQNSWESYYLEILMVTGLLAYIMNYIIGKNKNSRLAQAWFNTHRELLESNFT
LVGDDGTNKEATSTGKLNQENEHIYNLWCSGRVCCEGMLIQLRFLKRQDLLNVLARMMRPVSDQVAPGRPCSWLLACSACPGFKRAVPSQ
PFPYPGFLTTLCSAPIVCTSWPLTPTRSLGWKMAAPGLGRSSSRPTASSTQTHTTMTHYSRTTGCSTASGRTWTRSRHSCASCSAALWRA

--------------------------------------------------------------
>13814_13814_3_CCDC47-GH1_CCDC47_chr17_61838274_ENST00000225726_GH1_chr17_61995866_ENST00000351388_length(transcript)=1751nt_BP=1118nt
GTAGGAGGATTGGGATAGGCGAGGGCAGTTCCGGCCCAGGGGCGGGGATTATGTAATTTTCCCAAAAGCCCCACCTCGCCTCAGCCGGGC
GGGAGAGAGGGAGGTCTCGCGCTTTCCCCGGGGTTGCGTCCCGCCCCGCAGGCTGCGCGCAGGCGCTGACGAGCCGCTCGCATTCTACGT
AACGGACGGCGGAGGCTACGTGAAGAGAGGCGCGGCGTGACTGAGCTACGGTTCTGGCTGCGTCCTAGAGGCATCCGGGGCAGTAAAACC
GCTGCGATCGCGGAGGCGGCGGCCAGGCCGAGAGGCAGGCCGGGCAGGGGTGTCGGACGCAGGGCGCTGGGCCGGGTTTCGGCTTCGGCC
ACAGCTTTTTTTCTCAAGGTGCAATGAAAGCCTTCCACACTTTCTGTGTTGTCCTTCTGGTGTTTGGGAGTGTCTCTGAAGCCAAGTTTG
ATGATTTTGAGGATGAGGAGGACATAGTAGAGTATGATGATAATGACTTCGCTGAATTTGAGGATGTCATGGAAGACTCTGTTACTGAAT
CTCCTCAACGGGTCATAATCACTGAAGATGATGAAGATGAGACCACTGTGGAGTTGGAAGGGCAGGATGAAAACCAAGAAGGAGATTTTG
AAGATGCAGATACCCAGGAGGGAGATACTGAGAGTGAACCATATGATGATGAAGAATTTGAAGGTTATGAAGACAAACCAGATACTTCTT
CTAGCAAAAATAAAGACCCAATAACGATTGTTGATGTTCCTGCACACCTCCAGAACAGCTGGGAGAGTTATTATCTAGAAATTTTGATGG
TGACTGGTCTGCTTGCTTATATCATGAATTACATCATTGGGAAGAATAAAAACAGTCGCCTTGCACAGGCCTGGTTTAACACTCATAGGG
AGCTTTTGGAGAGCAACTTTACTTTAGTGGGGGATGATGGAACTAACAAAGAAGCCACAAGCACAGGAAAGTTGAACCAGGAGAATGAGC
ACATCTATAACCTGTGGTGTTCTGGTCGAGTGTGCTGTGAGGGCATGCTTATCCAGCTGAGGTTCCTCAAGAGACAAGACTTACTGAATG
TCCTGGCCCGGATGATGAGGCCAGTGAGTGATCAAGTGGCTCCCGGACGTCCCTGCTCCTGGCTTTTGGCCTGCTCTGCCTGCCCTGGCT
TCAAGAGGGCAGTGCCTTCCCAACCATTCCCTTATCCAGGCTTTTTGACAACGCTATGCTCCGCGCCCATCGTCTGCACCAGCTGGCCTT
TGACACCTACCAGGAGTTTAACCTAGAGCTGCTCCGCATCTCCCTGCTGCTCATCCAGTCGTGGCTGGAGCCCGTGCAGTTCCTCAGGAG
TGTCTTCGCCAACAGCCTGGTGTACGGCGCCTCTGACAGCAACGTCTATGACCTCCTAAAGGACCTAGAGGAAGGCATCCAAACGCTGAT
GGGGAGGCTGGAAGATGGCAGCCCCCGGACTGGGCAGATCTTCAAGCAGACCTACAGCAAGTTCGACACAAACTCACACAACGATGACGC
ACTACTCAAGAACTACGGGCTGCTCTACTGCTTCAGGAAGGACATGGACAAGGTCGAGACATTCCTGCGCATCGTGCAGTGCCGCTCTGT
GGAGGGCAGCTGTGGCTTCTAGCTGCCCGGGTGGCATCCCTGTGACCCCTCCCCAGTGCCTCTCCTGGCCCTGGAAGTTGCCACTCCAGT

>13814_13814_3_CCDC47-GH1_CCDC47_chr17_61838274_ENST00000225726_GH1_chr17_61995866_ENST00000351388_length(amino acids)=300AA_BP=245
MKAFHTFCVVLLVFGSVSEAKFDDFEDEEDIVEYDDNDFAEFEDVMEDSVTESPQRVIITEDDEDETTVELEGQDENQEGDFEDADTQEG
DTESEPYDDEEFEGYEDKPDTSSSKNKDPITIVDVPAHLQNSWESYYLEILMVTGLLAYIMNYIIGKNKNSRLAQAWFNTHRELLESNFT
LVGDDGTNKEATSTGKLNQENEHIYNLWCSGRVCCEGMLIQLRFLKRQDLLNVLARMMRPVSDQVAPGRPCSWLLACSACPGFKRAVPSQ

--------------------------------------------------------------
>13814_13814_4_CCDC47-GH1_CCDC47_chr17_61838274_ENST00000225726_GH1_chr17_61995866_ENST00000458650_length(transcript)=1823nt_BP=1118nt
GTAGGAGGATTGGGATAGGCGAGGGCAGTTCCGGCCCAGGGGCGGGGATTATGTAATTTTCCCAAAAGCCCCACCTCGCCTCAGCCGGGC
GGGAGAGAGGGAGGTCTCGCGCTTTCCCCGGGGTTGCGTCCCGCCCCGCAGGCTGCGCGCAGGCGCTGACGAGCCGCTCGCATTCTACGT
AACGGACGGCGGAGGCTACGTGAAGAGAGGCGCGGCGTGACTGAGCTACGGTTCTGGCTGCGTCCTAGAGGCATCCGGGGCAGTAAAACC
GCTGCGATCGCGGAGGCGGCGGCCAGGCCGAGAGGCAGGCCGGGCAGGGGTGTCGGACGCAGGGCGCTGGGCCGGGTTTCGGCTTCGGCC
ACAGCTTTTTTTCTCAAGGTGCAATGAAAGCCTTCCACACTTTCTGTGTTGTCCTTCTGGTGTTTGGGAGTGTCTCTGAAGCCAAGTTTG
ATGATTTTGAGGATGAGGAGGACATAGTAGAGTATGATGATAATGACTTCGCTGAATTTGAGGATGTCATGGAAGACTCTGTTACTGAAT
CTCCTCAACGGGTCATAATCACTGAAGATGATGAAGATGAGACCACTGTGGAGTTGGAAGGGCAGGATGAAAACCAAGAAGGAGATTTTG
AAGATGCAGATACCCAGGAGGGAGATACTGAGAGTGAACCATATGATGATGAAGAATTTGAAGGTTATGAAGACAAACCAGATACTTCTT
CTAGCAAAAATAAAGACCCAATAACGATTGTTGATGTTCCTGCACACCTCCAGAACAGCTGGGAGAGTTATTATCTAGAAATTTTGATGG
TGACTGGTCTGCTTGCTTATATCATGAATTACATCATTGGGAAGAATAAAAACAGTCGCCTTGCACAGGCCTGGTTTAACACTCATAGGG
AGCTTTTGGAGAGCAACTTTACTTTAGTGGGGGATGATGGAACTAACAAAGAAGCCACAAGCACAGGAAAGTTGAACCAGGAGAATGAGC
ACATCTATAACCTGTGGTGTTCTGGTCGAGTGTGCTGTGAGGGCATGCTTATCCAGCTGAGGTTCCTCAAGAGACAAGACTTACTGAATG
TCCTGGCCCGGATGATGAGGCCAGTGAGTGATCAAGTGGCTCCCGGACGTCCCTGCTCCTGGCTTTTGGCCTGCTCTGCCTGCCCTGGCT
TCAAGAGGGCAGTGCCTTCCCAACCATTCCCTTATCCAGGCTTTTTGACAACGCTATGCTCCGCGCCCATCGTCTGCACCAGCTGGCCTT
TGACACCTACCAGGAGTTTAACCCCCAGACCTCCCTCTGTTTCTCAGAGTCTATTCCGACACCCTCCAACAGGGAGGAAACACAACAGAA
ATCCAACCTAGAGCTGCTCCGCATCTCCCTGCTGCTCATCCAGTCGTGGCTGGAGCCCGTGCAGTTCCTCAGGAGTGTCTTCGCCAACAG
CCTGGTGTACGGCGCCTCTGACAGCAACGTCTATGACCTCCTAAAGGACCTAGAGGAAGGCATCCAAACGCTGATGGGGAGGCTGGAAGA
TGGCAGCCCCCGGACTGGGCAGATCTTCAAGCAGACCTACAGCAAGTTCGACACAAACTCACACAACGATGACGCACTACTCAAGAACTA
CGGGCTGCTCTACTGCTTCAGGAAGGACATGGACAAGGTCGAGACATTCCTGCGCATCGTGCAGTGCCGCTCTGTGGAGGGCAGCTGTGG
CTTCTAGCTGCCCGGGTGGCATCCCTGTGACCCCTCCCCAGTGCCTCTCCTGGCCCTGGAAGTTGCCACTCCAGTGCCCACCAGCCTTGT

>13814_13814_4_CCDC47-GH1_CCDC47_chr17_61838274_ENST00000225726_GH1_chr17_61995866_ENST00000458650_length(amino acids)=325AA_BP=245
MKAFHTFCVVLLVFGSVSEAKFDDFEDEEDIVEYDDNDFAEFEDVMEDSVTESPQRVIITEDDEDETTVELEGQDENQEGDFEDADTQEG
DTESEPYDDEEFEGYEDKPDTSSSKNKDPITIVDVPAHLQNSWESYYLEILMVTGLLAYIMNYIIGKNKNSRLAQAWFNTHRELLESNFT
LVGDDGTNKEATSTGKLNQENEHIYNLWCSGRVCCEGMLIQLRFLKRQDLLNVLARMMRPVSDQVAPGRPCSWLLACSACPGFKRAVPSQ

--------------------------------------------------------------
>13814_13814_5_CCDC47-GH1_CCDC47_chr17_61838274_ENST00000403162_GH1_chr17_61995866_ENST00000323322_length(transcript)=1750nt_BP=1000nt
AGAGGCGCGGCGTGACTGAGCTACGGTTCTGGCTGCGTCCTAGAGGCATCCGGGGCAGTAAAACCGCTGCGATCGCGGAGGCGGCGGCCA
GGCCGAGAGGCAGGCCGGGCAGGGGTGTCGGACGCAGGGCGCTGGGCCGGGTTTCGGCTTCGGCCACAGGAGTCATAGAGGCTGGGTGGT
CTGGCAAGGACTTGTGCATTTGAGAACTGACAGGTGCAGCGGAGACTTCTAAGAGGGAAAACCAAGCTTTTTTTCTCAAGGTGCAATGAA
AGCCTTCCACACTTTCTGTGTTGTCCTTCTGGTGTTTGGGAGTGTCTCTGAAGCCAAGTTTGATGATTTTGAGGATGAGGAGGACATAGT
AGAGTATGATGATAATGACTTCGCTGAATTTGAGGATGTCATGGAAGACTCTGTTACTGAATCTCCTCAACGGGTCATAATCACTGAAGA
TGATGAAGATGAGACCACTGTGGAGTTGGAAGGGCAGGATGAAAACCAAGAAGGAGATTTTGAAGATGCAGATACCCAGGAGGGAGATAC
TGAGAGTGAACCATATGATGATGAAGAATTTGAAGGTTATGAAGACAAACCAGATACTTCTTCTAGCAAAAATAAAGACCCAATAACGAT
TGTTGATGTTCCTGCACACCTCCAGAACAGCTGGGAGAGTTATTATCTAGAAATTTTGATGGTGACTGGTCTGCTTGCTTATATCATGAA
TTACATCATTGGGAAGAATAAAAACAGTCGCCTTGCACAGGCCTGGTTTAACACTCATAGGGAGCTTTTGGAGAGCAACTTTACTTTAGT
GGGGGATGATGGAACTAACAAAGAAGCCACAAGCACAGGAAAGTTGAACCAGGAGAATGAGCACATCTATAACCTGTGGTGTTCTGGTCG
AGTGTGCTGTGAGGGCATGCTTATCCAGCTGAGGTTCCTCAAGAGACAAGACTTACTGAATGTCCTGGCCCGGATGATGAGGCCAGTGAG
TGATCAAGTGGCTCCCGGACGTCCCTGCTCCTGGCTTTTGGCCTGCTCTGCCTGCCCTGGCTTCAAGAGGGCAGTGCCTTCCCAACCATT
CCCTTATCCAGGCTTTTTGACAACGCTATGCTCCGCGCCCATCGTCTGCACCAGCTGGCCTTTGACACCTACCAGGAGTTTGAAGAAGCC
TATATCCCAAAGGAACAGAAGTATTCATTCCTGCAGAACCCCCAGACCTCCCTCTGTTTCTCAGAGTCTATTCCGACACCCTCCAACAGG
GAGGAAACACAACAGAAATCCAACCTAGAGCTGCTCCGCATCTCCCTGCTGCTCATCCAGTCGTGGCTGGAGCCCGTGCAGTTCCTCAGG
AGTGTCTTCGCCAACAGCCTGGTGTACGGCGCCTCTGACAGCAACGTCTATGACCTCCTAAAGGACCTAGAGGAAGGCATCCAAACGCTG
ATGGGGAGGCTGGAAGATGGCAGCCCCCGGACTGGGCAGATCTTCAAGCAGACCTACAGCAAGTTCGACACAAACTCACACAACGATGAC
GCACTACTCAAGAACTACGGGCTGCTCTACTGCTTCAGGAAGGACATGGACAAGGTCGAGACATTCCTGCGCATCGTGCAGTGCCGCTCT
GTGGAGGGCAGCTGTGGCTTCTAGCTGCCCGGGTGGCATCCCTGTGACCCCTCCCCAGTGCCTCTCCTGGCCCTGGAAGTTGCCACTCCA

>13814_13814_5_CCDC47-GH1_CCDC47_chr17_61838274_ENST00000403162_GH1_chr17_61995866_ENST00000323322_length(amino acids)=340AA_BP=245
MKAFHTFCVVLLVFGSVSEAKFDDFEDEEDIVEYDDNDFAEFEDVMEDSVTESPQRVIITEDDEDETTVELEGQDENQEGDFEDADTQEG
DTESEPYDDEEFEGYEDKPDTSSSKNKDPITIVDVPAHLQNSWESYYLEILMVTGLLAYIMNYIIGKNKNSRLAQAWFNTHRELLESNFT
LVGDDGTNKEATSTGKLNQENEHIYNLWCSGRVCCEGMLIQLRFLKRQDLLNVLARMMRPVSDQVAPGRPCSWLLACSACPGFKRAVPSQ

--------------------------------------------------------------
>13814_13814_6_CCDC47-GH1_CCDC47_chr17_61838274_ENST00000403162_GH1_chr17_61995866_ENST00000342364_length(transcript)=1359nt_BP=1000nt
AGAGGCGCGGCGTGACTGAGCTACGGTTCTGGCTGCGTCCTAGAGGCATCCGGGGCAGTAAAACCGCTGCGATCGCGGAGGCGGCGGCCA
GGCCGAGAGGCAGGCCGGGCAGGGGTGTCGGACGCAGGGCGCTGGGCCGGGTTTCGGCTTCGGCCACAGGAGTCATAGAGGCTGGGTGGT
CTGGCAAGGACTTGTGCATTTGAGAACTGACAGGTGCAGCGGAGACTTCTAAGAGGGAAAACCAAGCTTTTTTTCTCAAGGTGCAATGAA
AGCCTTCCACACTTTCTGTGTTGTCCTTCTGGTGTTTGGGAGTGTCTCTGAAGCCAAGTTTGATGATTTTGAGGATGAGGAGGACATAGT
AGAGTATGATGATAATGACTTCGCTGAATTTGAGGATGTCATGGAAGACTCTGTTACTGAATCTCCTCAACGGGTCATAATCACTGAAGA
TGATGAAGATGAGACCACTGTGGAGTTGGAAGGGCAGGATGAAAACCAAGAAGGAGATTTTGAAGATGCAGATACCCAGGAGGGAGATAC
TGAGAGTGAACCATATGATGATGAAGAATTTGAAGGTTATGAAGACAAACCAGATACTTCTTCTAGCAAAAATAAAGACCCAATAACGAT
TGTTGATGTTCCTGCACACCTCCAGAACAGCTGGGAGAGTTATTATCTAGAAATTTTGATGGTGACTGGTCTGCTTGCTTATATCATGAA
TTACATCATTGGGAAGAATAAAAACAGTCGCCTTGCACAGGCCTGGTTTAACACTCATAGGGAGCTTTTGGAGAGCAACTTTACTTTAGT
GGGGGATGATGGAACTAACAAAGAAGCCACAAGCACAGGAAAGTTGAACCAGGAGAATGAGCACATCTATAACCTGTGGTGTTCTGGTCG
AGTGTGCTGTGAGGGCATGCTTATCCAGCTGAGGTTCCTCAAGAGACAAGACTTACTGAATGTCCTGGCCCGGATGATGAGGCCAGTGAG
TGATCAAGTGGCTCCCGGACGTCCCTGCTCCTGGCTTTTGGCCTGCTCTGCCTGCCCTGGCTTCAAGAGGGCAGTGCCTTCCCAACCATT
CCCTTATCCAGGCTTTTTGACAACGCTATGCTCCGCGCCCATCGTCTGCACCAGCTGGCCTTTGACACCTACCAGGAGTTTAGGCTGGAA
GATGGCAGCCCCCGGACTGGGCAGATCTTCAAGCAGACCTACAGCAAGTTCGACACAAACTCACACAACGATGACGCACTACTCAAGAAC
TACGGGCTGCTCTACTGCTTCAGGAAGGACATGGACAAGGTCGAGACATTCCTGCGCATCGTGCAGTGCCGCTCTGTGGAGGGCAGCTGT

>13814_13814_6_CCDC47-GH1_CCDC47_chr17_61838274_ENST00000403162_GH1_chr17_61995866_ENST00000342364_length(amino acids)=364AA_BP=245
MKAFHTFCVVLLVFGSVSEAKFDDFEDEEDIVEYDDNDFAEFEDVMEDSVTESPQRVIITEDDEDETTVELEGQDENQEGDFEDADTQEG
DTESEPYDDEEFEGYEDKPDTSSSKNKDPITIVDVPAHLQNSWESYYLEILMVTGLLAYIMNYIIGKNKNSRLAQAWFNTHRELLESNFT
LVGDDGTNKEATSTGKLNQENEHIYNLWCSGRVCCEGMLIQLRFLKRQDLLNVLARMMRPVSDQVAPGRPCSWLLACSACPGFKRAVPSQ
PFPYPGFLTTLCSAPIVCTSWPLTPTRSLGWKMAAPGLGRSSSRPTASSTQTHTTMTHYSRTTGCSTASGRTWTRSRHSCASCSAALWRA

--------------------------------------------------------------
>13814_13814_7_CCDC47-GH1_CCDC47_chr17_61838274_ENST00000403162_GH1_chr17_61995866_ENST00000351388_length(transcript)=1633nt_BP=1000nt
AGAGGCGCGGCGTGACTGAGCTACGGTTCTGGCTGCGTCCTAGAGGCATCCGGGGCAGTAAAACCGCTGCGATCGCGGAGGCGGCGGCCA
GGCCGAGAGGCAGGCCGGGCAGGGGTGTCGGACGCAGGGCGCTGGGCCGGGTTTCGGCTTCGGCCACAGGAGTCATAGAGGCTGGGTGGT
CTGGCAAGGACTTGTGCATTTGAGAACTGACAGGTGCAGCGGAGACTTCTAAGAGGGAAAACCAAGCTTTTTTTCTCAAGGTGCAATGAA
AGCCTTCCACACTTTCTGTGTTGTCCTTCTGGTGTTTGGGAGTGTCTCTGAAGCCAAGTTTGATGATTTTGAGGATGAGGAGGACATAGT
AGAGTATGATGATAATGACTTCGCTGAATTTGAGGATGTCATGGAAGACTCTGTTACTGAATCTCCTCAACGGGTCATAATCACTGAAGA
TGATGAAGATGAGACCACTGTGGAGTTGGAAGGGCAGGATGAAAACCAAGAAGGAGATTTTGAAGATGCAGATACCCAGGAGGGAGATAC
TGAGAGTGAACCATATGATGATGAAGAATTTGAAGGTTATGAAGACAAACCAGATACTTCTTCTAGCAAAAATAAAGACCCAATAACGAT
TGTTGATGTTCCTGCACACCTCCAGAACAGCTGGGAGAGTTATTATCTAGAAATTTTGATGGTGACTGGTCTGCTTGCTTATATCATGAA
TTACATCATTGGGAAGAATAAAAACAGTCGCCTTGCACAGGCCTGGTTTAACACTCATAGGGAGCTTTTGGAGAGCAACTTTACTTTAGT
GGGGGATGATGGAACTAACAAAGAAGCCACAAGCACAGGAAAGTTGAACCAGGAGAATGAGCACATCTATAACCTGTGGTGTTCTGGTCG
AGTGTGCTGTGAGGGCATGCTTATCCAGCTGAGGTTCCTCAAGAGACAAGACTTACTGAATGTCCTGGCCCGGATGATGAGGCCAGTGAG
TGATCAAGTGGCTCCCGGACGTCCCTGCTCCTGGCTTTTGGCCTGCTCTGCCTGCCCTGGCTTCAAGAGGGCAGTGCCTTCCCAACCATT
CCCTTATCCAGGCTTTTTGACAACGCTATGCTCCGCGCCCATCGTCTGCACCAGCTGGCCTTTGACACCTACCAGGAGTTTAACCTAGAG
CTGCTCCGCATCTCCCTGCTGCTCATCCAGTCGTGGCTGGAGCCCGTGCAGTTCCTCAGGAGTGTCTTCGCCAACAGCCTGGTGTACGGC
GCCTCTGACAGCAACGTCTATGACCTCCTAAAGGACCTAGAGGAAGGCATCCAAACGCTGATGGGGAGGCTGGAAGATGGCAGCCCCCGG
ACTGGGCAGATCTTCAAGCAGACCTACAGCAAGTTCGACACAAACTCACACAACGATGACGCACTACTCAAGAACTACGGGCTGCTCTAC
TGCTTCAGGAAGGACATGGACAAGGTCGAGACATTCCTGCGCATCGTGCAGTGCCGCTCTGTGGAGGGCAGCTGTGGCTTCTAGCTGCCC
GGGTGGCATCCCTGTGACCCCTCCCCAGTGCCTCTCCTGGCCCTGGAAGTTGCCACTCCAGTGCCCACCAGCCTTGTCCTAATAAAATTA

>13814_13814_7_CCDC47-GH1_CCDC47_chr17_61838274_ENST00000403162_GH1_chr17_61995866_ENST00000351388_length(amino acids)=300AA_BP=245
MKAFHTFCVVLLVFGSVSEAKFDDFEDEEDIVEYDDNDFAEFEDVMEDSVTESPQRVIITEDDEDETTVELEGQDENQEGDFEDADTQEG
DTESEPYDDEEFEGYEDKPDTSSSKNKDPITIVDVPAHLQNSWESYYLEILMVTGLLAYIMNYIIGKNKNSRLAQAWFNTHRELLESNFT
LVGDDGTNKEATSTGKLNQENEHIYNLWCSGRVCCEGMLIQLRFLKRQDLLNVLARMMRPVSDQVAPGRPCSWLLACSACPGFKRAVPSQ

--------------------------------------------------------------
>13814_13814_8_CCDC47-GH1_CCDC47_chr17_61838274_ENST00000403162_GH1_chr17_61995866_ENST00000458650_length(transcript)=1705nt_BP=1000nt
AGAGGCGCGGCGTGACTGAGCTACGGTTCTGGCTGCGTCCTAGAGGCATCCGGGGCAGTAAAACCGCTGCGATCGCGGAGGCGGCGGCCA
GGCCGAGAGGCAGGCCGGGCAGGGGTGTCGGACGCAGGGCGCTGGGCCGGGTTTCGGCTTCGGCCACAGGAGTCATAGAGGCTGGGTGGT
CTGGCAAGGACTTGTGCATTTGAGAACTGACAGGTGCAGCGGAGACTTCTAAGAGGGAAAACCAAGCTTTTTTTCTCAAGGTGCAATGAA
AGCCTTCCACACTTTCTGTGTTGTCCTTCTGGTGTTTGGGAGTGTCTCTGAAGCCAAGTTTGATGATTTTGAGGATGAGGAGGACATAGT
AGAGTATGATGATAATGACTTCGCTGAATTTGAGGATGTCATGGAAGACTCTGTTACTGAATCTCCTCAACGGGTCATAATCACTGAAGA
TGATGAAGATGAGACCACTGTGGAGTTGGAAGGGCAGGATGAAAACCAAGAAGGAGATTTTGAAGATGCAGATACCCAGGAGGGAGATAC
TGAGAGTGAACCATATGATGATGAAGAATTTGAAGGTTATGAAGACAAACCAGATACTTCTTCTAGCAAAAATAAAGACCCAATAACGAT
TGTTGATGTTCCTGCACACCTCCAGAACAGCTGGGAGAGTTATTATCTAGAAATTTTGATGGTGACTGGTCTGCTTGCTTATATCATGAA
TTACATCATTGGGAAGAATAAAAACAGTCGCCTTGCACAGGCCTGGTTTAACACTCATAGGGAGCTTTTGGAGAGCAACTTTACTTTAGT
GGGGGATGATGGAACTAACAAAGAAGCCACAAGCACAGGAAAGTTGAACCAGGAGAATGAGCACATCTATAACCTGTGGTGTTCTGGTCG
AGTGTGCTGTGAGGGCATGCTTATCCAGCTGAGGTTCCTCAAGAGACAAGACTTACTGAATGTCCTGGCCCGGATGATGAGGCCAGTGAG
TGATCAAGTGGCTCCCGGACGTCCCTGCTCCTGGCTTTTGGCCTGCTCTGCCTGCCCTGGCTTCAAGAGGGCAGTGCCTTCCCAACCATT
CCCTTATCCAGGCTTTTTGACAACGCTATGCTCCGCGCCCATCGTCTGCACCAGCTGGCCTTTGACACCTACCAGGAGTTTAACCCCCAG
ACCTCCCTCTGTTTCTCAGAGTCTATTCCGACACCCTCCAACAGGGAGGAAACACAACAGAAATCCAACCTAGAGCTGCTCCGCATCTCC
CTGCTGCTCATCCAGTCGTGGCTGGAGCCCGTGCAGTTCCTCAGGAGTGTCTTCGCCAACAGCCTGGTGTACGGCGCCTCTGACAGCAAC
GTCTATGACCTCCTAAAGGACCTAGAGGAAGGCATCCAAACGCTGATGGGGAGGCTGGAAGATGGCAGCCCCCGGACTGGGCAGATCTTC
AAGCAGACCTACAGCAAGTTCGACACAAACTCACACAACGATGACGCACTACTCAAGAACTACGGGCTGCTCTACTGCTTCAGGAAGGAC
ATGGACAAGGTCGAGACATTCCTGCGCATCGTGCAGTGCCGCTCTGTGGAGGGCAGCTGTGGCTTCTAGCTGCCCGGGTGGCATCCCTGT

>13814_13814_8_CCDC47-GH1_CCDC47_chr17_61838274_ENST00000403162_GH1_chr17_61995866_ENST00000458650_length(amino acids)=325AA_BP=245
MKAFHTFCVVLLVFGSVSEAKFDDFEDEEDIVEYDDNDFAEFEDVMEDSVTESPQRVIITEDDEDETTVELEGQDENQEGDFEDADTQEG
DTESEPYDDEEFEGYEDKPDTSSSKNKDPITIVDVPAHLQNSWESYYLEILMVTGLLAYIMNYIIGKNKNSRLAQAWFNTHRELLESNFT
LVGDDGTNKEATSTGKLNQENEHIYNLWCSGRVCCEGMLIQLRFLKRQDLLNVLARMMRPVSDQVAPGRPCSWLLACSACPGFKRAVPSQ

--------------------------------------------------------------
>13814_13814_9_CCDC47-GH1_CCDC47_chr17_61838274_ENST00000582252_GH1_chr17_61995866_ENST00000323322_length(transcript)=1663nt_BP=913nt
AGAGGCGCGGCGTGACTGAGCTACGGTTCTGGCTGCGTCCTAGAGGCATCCGGGGCAGTAAAACCGCTGCGATCGCGGAGGCGGCGGCCA
GGCCGAGAGGCAGGCCGGGCAGGGGTGTCGGACGCAGGGCGCTGGGCCGGGTTTCGGCTTCGGCCACAGCTTTTTTTCTCAAGGTGCAAT
GAAAGCCTTCCACACTTTCTGTGTTGTCCTTCTGGTGTTTGGGAGTGTCTCTGAAGCCAAGTTTGATGATTTTGAGGATGAGGAGGACAT
AGTAGAGTATGATGATAATGACTTCGCTGAATTTGAGGATGTCATGGAAGACTCTGTTACTGAATCTCCTCAACGGGTCATAATCACTGA
AGATGATGAAGATGAGACCACTGTGGAGTTGGAAGGGCAGGATGAAAACCAAGAAGGAGATTTTGAAGATGCAGATACCCAGGAGGGAGA
TACTGAGAGTGAACCATATGATGATGAAGAATTTGAAGGTTATGAAGACAAACCAGATACTTCTTCTAGCAAAAATAAAGACCCAATAAC
GATTGTTGATGTTCCTGCACACCTCCAGAACAGCTGGGAGAGTTATTATCTAGAAATTTTGATGGTGACTGGTCTGCTTGCTTATATCAT
GAATTACATCATTGGGAAGAATAAAAACAGTCGCCTTGCACAGGCCTGGTTTAACACTCATAGGGAGCTTTTGGAGAGCAACTTTACTTT
AGTGGGGGATGATGGAACTAACAAAGAAGCCACAAGCACAGGAAAGTTGAACCAGGAGAATGAGCACATCTATAACCTGTGGTGTTCTGG
TCGAGTGTGCTGTGAGGGCATGCTTATCCAGCTGAGGTTCCTCAAGAGACAAGACTTACTGAATGTCCTGGCCCGGATGATGAGGCCAGT
GAGTGATCAAGTGGCTCCCGGACGTCCCTGCTCCTGGCTTTTGGCCTGCTCTGCCTGCCCTGGCTTCAAGAGGGCAGTGCCTTCCCAACC
ATTCCCTTATCCAGGCTTTTTGACAACGCTATGCTCCGCGCCCATCGTCTGCACCAGCTGGCCTTTGACACCTACCAGGAGTTTGAAGAA
GCCTATATCCCAAAGGAACAGAAGTATTCATTCCTGCAGAACCCCCAGACCTCCCTCTGTTTCTCAGAGTCTATTCCGACACCCTCCAAC
AGGGAGGAAACACAACAGAAATCCAACCTAGAGCTGCTCCGCATCTCCCTGCTGCTCATCCAGTCGTGGCTGGAGCCCGTGCAGTTCCTC
AGGAGTGTCTTCGCCAACAGCCTGGTGTACGGCGCCTCTGACAGCAACGTCTATGACCTCCTAAAGGACCTAGAGGAAGGCATCCAAACG
CTGATGGGGAGGCTGGAAGATGGCAGCCCCCGGACTGGGCAGATCTTCAAGCAGACCTACAGCAAGTTCGACACAAACTCACACAACGAT
GACGCACTACTCAAGAACTACGGGCTGCTCTACTGCTTCAGGAAGGACATGGACAAGGTCGAGACATTCCTGCGCATCGTGCAGTGCCGC
TCTGTGGAGGGCAGCTGTGGCTTCTAGCTGCCCGGGTGGCATCCCTGTGACCCCTCCCCAGTGCCTCTCCTGGCCCTGGAAGTTGCCACT

>13814_13814_9_CCDC47-GH1_CCDC47_chr17_61838274_ENST00000582252_GH1_chr17_61995866_ENST00000323322_length(amino acids)=340AA_BP=245
MKAFHTFCVVLLVFGSVSEAKFDDFEDEEDIVEYDDNDFAEFEDVMEDSVTESPQRVIITEDDEDETTVELEGQDENQEGDFEDADTQEG
DTESEPYDDEEFEGYEDKPDTSSSKNKDPITIVDVPAHLQNSWESYYLEILMVTGLLAYIMNYIIGKNKNSRLAQAWFNTHRELLESNFT
LVGDDGTNKEATSTGKLNQENEHIYNLWCSGRVCCEGMLIQLRFLKRQDLLNVLARMMRPVSDQVAPGRPCSWLLACSACPGFKRAVPSQ

--------------------------------------------------------------
>13814_13814_10_CCDC47-GH1_CCDC47_chr17_61838274_ENST00000582252_GH1_chr17_61995866_ENST00000342364_length(transcript)=1272nt_BP=913nt
AGAGGCGCGGCGTGACTGAGCTACGGTTCTGGCTGCGTCCTAGAGGCATCCGGGGCAGTAAAACCGCTGCGATCGCGGAGGCGGCGGCCA
GGCCGAGAGGCAGGCCGGGCAGGGGTGTCGGACGCAGGGCGCTGGGCCGGGTTTCGGCTTCGGCCACAGCTTTTTTTCTCAAGGTGCAAT
GAAAGCCTTCCACACTTTCTGTGTTGTCCTTCTGGTGTTTGGGAGTGTCTCTGAAGCCAAGTTTGATGATTTTGAGGATGAGGAGGACAT
AGTAGAGTATGATGATAATGACTTCGCTGAATTTGAGGATGTCATGGAAGACTCTGTTACTGAATCTCCTCAACGGGTCATAATCACTGA
AGATGATGAAGATGAGACCACTGTGGAGTTGGAAGGGCAGGATGAAAACCAAGAAGGAGATTTTGAAGATGCAGATACCCAGGAGGGAGA
TACTGAGAGTGAACCATATGATGATGAAGAATTTGAAGGTTATGAAGACAAACCAGATACTTCTTCTAGCAAAAATAAAGACCCAATAAC
GATTGTTGATGTTCCTGCACACCTCCAGAACAGCTGGGAGAGTTATTATCTAGAAATTTTGATGGTGACTGGTCTGCTTGCTTATATCAT
GAATTACATCATTGGGAAGAATAAAAACAGTCGCCTTGCACAGGCCTGGTTTAACACTCATAGGGAGCTTTTGGAGAGCAACTTTACTTT
AGTGGGGGATGATGGAACTAACAAAGAAGCCACAAGCACAGGAAAGTTGAACCAGGAGAATGAGCACATCTATAACCTGTGGTGTTCTGG
TCGAGTGTGCTGTGAGGGCATGCTTATCCAGCTGAGGTTCCTCAAGAGACAAGACTTACTGAATGTCCTGGCCCGGATGATGAGGCCAGT
GAGTGATCAAGTGGCTCCCGGACGTCCCTGCTCCTGGCTTTTGGCCTGCTCTGCCTGCCCTGGCTTCAAGAGGGCAGTGCCTTCCCAACC
ATTCCCTTATCCAGGCTTTTTGACAACGCTATGCTCCGCGCCCATCGTCTGCACCAGCTGGCCTTTGACACCTACCAGGAGTTTAGGCTG
GAAGATGGCAGCCCCCGGACTGGGCAGATCTTCAAGCAGACCTACAGCAAGTTCGACACAAACTCACACAACGATGACGCACTACTCAAG
AACTACGGGCTGCTCTACTGCTTCAGGAAGGACATGGACAAGGTCGAGACATTCCTGCGCATCGTGCAGTGCCGCTCTGTGGAGGGCAGC

>13814_13814_10_CCDC47-GH1_CCDC47_chr17_61838274_ENST00000582252_GH1_chr17_61995866_ENST00000342364_length(amino acids)=364AA_BP=245
MKAFHTFCVVLLVFGSVSEAKFDDFEDEEDIVEYDDNDFAEFEDVMEDSVTESPQRVIITEDDEDETTVELEGQDENQEGDFEDADTQEG
DTESEPYDDEEFEGYEDKPDTSSSKNKDPITIVDVPAHLQNSWESYYLEILMVTGLLAYIMNYIIGKNKNSRLAQAWFNTHRELLESNFT
LVGDDGTNKEATSTGKLNQENEHIYNLWCSGRVCCEGMLIQLRFLKRQDLLNVLARMMRPVSDQVAPGRPCSWLLACSACPGFKRAVPSQ
PFPYPGFLTTLCSAPIVCTSWPLTPTRSLGWKMAAPGLGRSSSRPTASSTQTHTTMTHYSRTTGCSTASGRTWTRSRHSCASCSAALWRA

--------------------------------------------------------------
>13814_13814_11_CCDC47-GH1_CCDC47_chr17_61838274_ENST00000582252_GH1_chr17_61995866_ENST00000351388_length(transcript)=1546nt_BP=913nt
AGAGGCGCGGCGTGACTGAGCTACGGTTCTGGCTGCGTCCTAGAGGCATCCGGGGCAGTAAAACCGCTGCGATCGCGGAGGCGGCGGCCA
GGCCGAGAGGCAGGCCGGGCAGGGGTGTCGGACGCAGGGCGCTGGGCCGGGTTTCGGCTTCGGCCACAGCTTTTTTTCTCAAGGTGCAAT
GAAAGCCTTCCACACTTTCTGTGTTGTCCTTCTGGTGTTTGGGAGTGTCTCTGAAGCCAAGTTTGATGATTTTGAGGATGAGGAGGACAT
AGTAGAGTATGATGATAATGACTTCGCTGAATTTGAGGATGTCATGGAAGACTCTGTTACTGAATCTCCTCAACGGGTCATAATCACTGA
AGATGATGAAGATGAGACCACTGTGGAGTTGGAAGGGCAGGATGAAAACCAAGAAGGAGATTTTGAAGATGCAGATACCCAGGAGGGAGA
TACTGAGAGTGAACCATATGATGATGAAGAATTTGAAGGTTATGAAGACAAACCAGATACTTCTTCTAGCAAAAATAAAGACCCAATAAC
GATTGTTGATGTTCCTGCACACCTCCAGAACAGCTGGGAGAGTTATTATCTAGAAATTTTGATGGTGACTGGTCTGCTTGCTTATATCAT
GAATTACATCATTGGGAAGAATAAAAACAGTCGCCTTGCACAGGCCTGGTTTAACACTCATAGGGAGCTTTTGGAGAGCAACTTTACTTT
AGTGGGGGATGATGGAACTAACAAAGAAGCCACAAGCACAGGAAAGTTGAACCAGGAGAATGAGCACATCTATAACCTGTGGTGTTCTGG
TCGAGTGTGCTGTGAGGGCATGCTTATCCAGCTGAGGTTCCTCAAGAGACAAGACTTACTGAATGTCCTGGCCCGGATGATGAGGCCAGT
GAGTGATCAAGTGGCTCCCGGACGTCCCTGCTCCTGGCTTTTGGCCTGCTCTGCCTGCCCTGGCTTCAAGAGGGCAGTGCCTTCCCAACC
ATTCCCTTATCCAGGCTTTTTGACAACGCTATGCTCCGCGCCCATCGTCTGCACCAGCTGGCCTTTGACACCTACCAGGAGTTTAACCTA
GAGCTGCTCCGCATCTCCCTGCTGCTCATCCAGTCGTGGCTGGAGCCCGTGCAGTTCCTCAGGAGTGTCTTCGCCAACAGCCTGGTGTAC
GGCGCCTCTGACAGCAACGTCTATGACCTCCTAAAGGACCTAGAGGAAGGCATCCAAACGCTGATGGGGAGGCTGGAAGATGGCAGCCCC
CGGACTGGGCAGATCTTCAAGCAGACCTACAGCAAGTTCGACACAAACTCACACAACGATGACGCACTACTCAAGAACTACGGGCTGCTC
TACTGCTTCAGGAAGGACATGGACAAGGTCGAGACATTCCTGCGCATCGTGCAGTGCCGCTCTGTGGAGGGCAGCTGTGGCTTCTAGCTG
CCCGGGTGGCATCCCTGTGACCCCTCCCCAGTGCCTCTCCTGGCCCTGGAAGTTGCCACTCCAGTGCCCACCAGCCTTGTCCTAATAAAA

>13814_13814_11_CCDC47-GH1_CCDC47_chr17_61838274_ENST00000582252_GH1_chr17_61995866_ENST00000351388_length(amino acids)=300AA_BP=245
MKAFHTFCVVLLVFGSVSEAKFDDFEDEEDIVEYDDNDFAEFEDVMEDSVTESPQRVIITEDDEDETTVELEGQDENQEGDFEDADTQEG
DTESEPYDDEEFEGYEDKPDTSSSKNKDPITIVDVPAHLQNSWESYYLEILMVTGLLAYIMNYIIGKNKNSRLAQAWFNTHRELLESNFT
LVGDDGTNKEATSTGKLNQENEHIYNLWCSGRVCCEGMLIQLRFLKRQDLLNVLARMMRPVSDQVAPGRPCSWLLACSACPGFKRAVPSQ

--------------------------------------------------------------
>13814_13814_12_CCDC47-GH1_CCDC47_chr17_61838274_ENST00000582252_GH1_chr17_61995866_ENST00000458650_length(transcript)=1618nt_BP=913nt
AGAGGCGCGGCGTGACTGAGCTACGGTTCTGGCTGCGTCCTAGAGGCATCCGGGGCAGTAAAACCGCTGCGATCGCGGAGGCGGCGGCCA
GGCCGAGAGGCAGGCCGGGCAGGGGTGTCGGACGCAGGGCGCTGGGCCGGGTTTCGGCTTCGGCCACAGCTTTTTTTCTCAAGGTGCAAT
GAAAGCCTTCCACACTTTCTGTGTTGTCCTTCTGGTGTTTGGGAGTGTCTCTGAAGCCAAGTTTGATGATTTTGAGGATGAGGAGGACAT
AGTAGAGTATGATGATAATGACTTCGCTGAATTTGAGGATGTCATGGAAGACTCTGTTACTGAATCTCCTCAACGGGTCATAATCACTGA
AGATGATGAAGATGAGACCACTGTGGAGTTGGAAGGGCAGGATGAAAACCAAGAAGGAGATTTTGAAGATGCAGATACCCAGGAGGGAGA
TACTGAGAGTGAACCATATGATGATGAAGAATTTGAAGGTTATGAAGACAAACCAGATACTTCTTCTAGCAAAAATAAAGACCCAATAAC
GATTGTTGATGTTCCTGCACACCTCCAGAACAGCTGGGAGAGTTATTATCTAGAAATTTTGATGGTGACTGGTCTGCTTGCTTATATCAT
GAATTACATCATTGGGAAGAATAAAAACAGTCGCCTTGCACAGGCCTGGTTTAACACTCATAGGGAGCTTTTGGAGAGCAACTTTACTTT
AGTGGGGGATGATGGAACTAACAAAGAAGCCACAAGCACAGGAAAGTTGAACCAGGAGAATGAGCACATCTATAACCTGTGGTGTTCTGG
TCGAGTGTGCTGTGAGGGCATGCTTATCCAGCTGAGGTTCCTCAAGAGACAAGACTTACTGAATGTCCTGGCCCGGATGATGAGGCCAGT
GAGTGATCAAGTGGCTCCCGGACGTCCCTGCTCCTGGCTTTTGGCCTGCTCTGCCTGCCCTGGCTTCAAGAGGGCAGTGCCTTCCCAACC
ATTCCCTTATCCAGGCTTTTTGACAACGCTATGCTCCGCGCCCATCGTCTGCACCAGCTGGCCTTTGACACCTACCAGGAGTTTAACCCC
CAGACCTCCCTCTGTTTCTCAGAGTCTATTCCGACACCCTCCAACAGGGAGGAAACACAACAGAAATCCAACCTAGAGCTGCTCCGCATC
TCCCTGCTGCTCATCCAGTCGTGGCTGGAGCCCGTGCAGTTCCTCAGGAGTGTCTTCGCCAACAGCCTGGTGTACGGCGCCTCTGACAGC
AACGTCTATGACCTCCTAAAGGACCTAGAGGAAGGCATCCAAACGCTGATGGGGAGGCTGGAAGATGGCAGCCCCCGGACTGGGCAGATC
TTCAAGCAGACCTACAGCAAGTTCGACACAAACTCACACAACGATGACGCACTACTCAAGAACTACGGGCTGCTCTACTGCTTCAGGAAG
GACATGGACAAGGTCGAGACATTCCTGCGCATCGTGCAGTGCCGCTCTGTGGAGGGCAGCTGTGGCTTCTAGCTGCCCGGGTGGCATCCC

>13814_13814_12_CCDC47-GH1_CCDC47_chr17_61838274_ENST00000582252_GH1_chr17_61995866_ENST00000458650_length(amino acids)=325AA_BP=245
MKAFHTFCVVLLVFGSVSEAKFDDFEDEEDIVEYDDNDFAEFEDVMEDSVTESPQRVIITEDDEDETTVELEGQDENQEGDFEDADTQEG
DTESEPYDDEEFEGYEDKPDTSSSKNKDPITIVDVPAHLQNSWESYYLEILMVTGLLAYIMNYIIGKNKNSRLAQAWFNTHRELLESNFT
LVGDDGTNKEATSTGKLNQENEHIYNLWCSGRVCCEGMLIQLRFLKRQDLLNVLARMMRPVSDQVAPGRPCSWLLACSACPGFKRAVPSQ

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Fusion Gene PPI Analysis for CCDC47-GH1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CCDC47-GH1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CCDC47-GH1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneCCDC47C0343073Wooly hair1GENOMICS_ENGLAND
HgeneCCDC47C0557874Global developmental delay1GENOMICS_ENGLAND
HgeneCCDC47C3714756Intellectual Disability1GENOMICS_ENGLAND
HgeneCCDC47C4021780Abnormality of the liver1GENOMICS_ENGLAND
HgeneCCDC47C4748898TRICHOHEPATONEURODEVELOPMENTAL SYNDROME1GENOMICS_ENGLAND
TgeneC0001206Acromegaly7CTD_human
TgeneC0001973Alcoholic Intoxication, Chronic5PSYGENET
TgeneC0271567Isolated Growth Hormone Deficiency, Type II4CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
TgeneC1849779Kowarski syndrome4CTD_human;ORPHANET;UNIPROT
TgeneC0011570Mental Depression3PSYGENET
TgeneC0011581Depressive disorder3PSYGENET
TgeneC2748571Isolated Growth Hormone Deficiency, Type IB3CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
TgeneC0024668Mammary Neoplasms, Experimental2CTD_human
TgeneC0342573PITUITARY DWARFISM I2CTD_human;GENOMICS_ENGLAND;ORPHANET
TgeneC0346302Growth Hormone-Secreting Pituitary Adenoma2CTD_human
TgeneC3489630Somatotrophinoma, Familial2CTD_human
TgeneC4748435ISOLATED GROWTH HORMONE DEFICIENCY, TYPE V2ORPHANET
TgeneC0007222Cardiovascular Diseases1CTD_human
TgeneC0018273Growth Disorders1CTD_human
TgeneC0021655Insulin Resistance1CTD_human
TgeneC0023893Liver Cirrhosis, Experimental1CTD_human
TgeneC0026846Muscular Atrophy1CTD_human
TgeneC0028754Obesity1CTD_human
TgeneC0032000Pituitary Adenoma1CTD_human
TgeneC0032019Pituitary Neoplasms1CTD_human
TgeneC0032461Polycythemia1CTD_human
TgeneC0041408Turner Syndrome1CTD_human
TgeneC0043094Weight Gain1CTD_human
TgeneC0242526Gonadal Dysgenesis, 45,X1CTD_human
TgeneC0242528Azotemia1CTD_human
TgeneC0270948Neurogenic Muscular Atrophy1CTD_human
TgeneC0346300Pituitary carcinoma1CTD_human
TgeneC0920563Insulin Sensitivity1CTD_human
TgeneC1527168Bonnevie-Ullrich Syndrome1CTD_human
TgeneC1527405Erythrocytosis1CTD_human