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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ACTR3B-JMJD1C (FusionGDB2 ID:HG57180TG221037)

Fusion Gene Summary for ACTR3B-JMJD1C

check button Fusion gene summary
Fusion gene informationFusion gene name: ACTR3B-JMJD1C
Fusion gene ID: hg57180tg221037
HgeneTgene
Gene symbol

ACTR3B

JMJD1C

Gene ID

57180

221037

Gene nameactin related protein 3Bjumonji domain containing 1C
SynonymsARP11|ARP3BETAKDM3C|TRIP-8|TRIP8
Cytomap('ACTR3B')('JMJD1C')

7q36.1-q36.2

10q21.3

Type of geneprotein-codingprotein-coding
Descriptionactin-related protein 3BARP3 actin related protein 3 homolog BARP3-betaactin-like protein 3Bactin-related protein 3-betaactin-related protein ARP4actin-related protein Arp11probable JmjC domain-containing histone demethylation protein 2CTR-interacting protein 8thyroid hormone receptor interactor 8thyroid receptor-interacting protein 8
Modification date2020031320200313
UniProtAcc.

Q15652

Ensembl transtripts involved in fusion geneENST00000256001, ENST00000377776, 
ENST00000397282, ENST00000537264, 
ENST00000488782, 
Fusion gene scores* DoF score6 X 4 X 4=9619 X 16 X 5=1520
# samples 617
** MAII scorelog2(6/96*10)=-0.678071905112638
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(17/1520*10)=-3.16046467219325
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ACTR3B [Title/Abstract] AND JMJD1C [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointACTR3B(152522207)-JMJD1C(65140242), # samples:1
Anticipated loss of major functional domain due to fusion event.ACTR3B-JMJD1C seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ACTR3B-JMJD1C seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across ACTR3B (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across JMJD1C (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4COADTCGA-A6-5656ACTR3Bchr7

152522207

+JMJD1Cchr10

65140242

-


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Fusion Gene ORF analysis for ACTR3B-JMJD1C

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000256001ENST00000399251ACTR3Bchr7

152522207

+JMJD1Cchr10

65140242

-
5CDS-5UTRENST00000377776ENST00000399251ACTR3Bchr7

152522207

+JMJD1Cchr10

65140242

-
5CDS-5UTRENST00000397282ENST00000399251ACTR3Bchr7

152522207

+JMJD1Cchr10

65140242

-
5CDS-5UTRENST00000537264ENST00000399251ACTR3Bchr7

152522207

+JMJD1Cchr10

65140242

-
5CDS-intronENST00000256001ENST00000402544ACTR3Bchr7

152522207

+JMJD1Cchr10

65140242

-
5CDS-intronENST00000256001ENST00000489372ACTR3Bchr7

152522207

+JMJD1Cchr10

65140242

-
5CDS-intronENST00000256001ENST00000542921ACTR3Bchr7

152522207

+JMJD1Cchr10

65140242

-
5CDS-intronENST00000377776ENST00000402544ACTR3Bchr7

152522207

+JMJD1Cchr10

65140242

-
5CDS-intronENST00000377776ENST00000489372ACTR3Bchr7

152522207

+JMJD1Cchr10

65140242

-
5CDS-intronENST00000377776ENST00000542921ACTR3Bchr7

152522207

+JMJD1Cchr10

65140242

-
5CDS-intronENST00000397282ENST00000402544ACTR3Bchr7

152522207

+JMJD1Cchr10

65140242

-
5CDS-intronENST00000397282ENST00000489372ACTR3Bchr7

152522207

+JMJD1Cchr10

65140242

-
5CDS-intronENST00000397282ENST00000542921ACTR3Bchr7

152522207

+JMJD1Cchr10

65140242

-
5CDS-intronENST00000537264ENST00000402544ACTR3Bchr7

152522207

+JMJD1Cchr10

65140242

-
5CDS-intronENST00000537264ENST00000489372ACTR3Bchr7

152522207

+JMJD1Cchr10

65140242

-
5CDS-intronENST00000537264ENST00000542921ACTR3Bchr7

152522207

+JMJD1Cchr10

65140242

-
In-frameENST00000256001ENST00000399262ACTR3Bchr7

152522207

+JMJD1Cchr10

65140242

-
In-frameENST00000377776ENST00000399262ACTR3Bchr7

152522207

+JMJD1Cchr10

65140242

-
In-frameENST00000397282ENST00000399262ACTR3Bchr7

152522207

+JMJD1Cchr10

65140242

-
In-frameENST00000537264ENST00000399262ACTR3Bchr7

152522207

+JMJD1Cchr10

65140242

-
intron-3CDSENST00000488782ENST00000399262ACTR3Bchr7

152522207

+JMJD1Cchr10

65140242

-
intron-5UTRENST00000488782ENST00000399251ACTR3Bchr7

152522207

+JMJD1Cchr10

65140242

-
intron-intronENST00000488782ENST00000402544ACTR3Bchr7

152522207

+JMJD1Cchr10

65140242

-
intron-intronENST00000488782ENST00000489372ACTR3Bchr7

152522207

+JMJD1Cchr10

65140242

-
intron-intronENST00000488782ENST00000542921ACTR3Bchr7

152522207

+JMJD1Cchr10

65140242

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000377776ACTR3Bchr7152522207+ENST00000399262JMJD1Cchr1065140242-936410854785392830
ENST00000256001ACTR3Bchr7152522207+ENST00000399262JMJD1Cchr1065140242-936410854785392830
ENST00000397282ACTR3Bchr7152522207+ENST00000399262JMJD1Cchr1065140242-926999019284442750
ENST00000537264ACTR3Bchr7152522207+ENST00000399262JMJD1Cchr1065140242-915988010983342741

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000377776ENST00000399262ACTR3Bchr7152522207+JMJD1Cchr1065140242-0.0002755440.99972445
ENST00000256001ENST00000399262ACTR3Bchr7152522207+JMJD1Cchr1065140242-0.0002755440.99972445
ENST00000397282ENST00000399262ACTR3Bchr7152522207+JMJD1Cchr1065140242-0.0003217410.99967825
ENST00000537264ENST00000399262ACTR3Bchr7152522207+JMJD1Cchr1065140242-0.0002794150.9997205

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Fusion Genomic Features for ACTR3B-JMJD1C


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for ACTR3B-JMJD1C


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr7:152522207/chr10:65140242)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.JMJD1C

Q15652

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Probable histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May be involved in hormone-dependent transcriptional activation, by participating in recruitment to androgen-receptor target genes (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneJMJD1Cchr7:152522207chr10:65140242ENST000003992510252274_24980477.0DomainJmjC
TgeneJMJD1Cchr7:152522207chr10:65140242ENST000003992620262274_2498562541.0DomainJmjC
TgeneJMJD1Cchr7:152522207chr10:65140242ENST000005429210252274_249802359.0DomainJmjC
TgeneJMJD1Cchr7:152522207chr10:65140242ENST000003992510252066_20700477.0MotifNote=LXXLL motif
TgeneJMJD1Cchr7:152522207chr10:65140242ENST000003992620262066_2070562541.0MotifNote=LXXLL motif
TgeneJMJD1Cchr7:152522207chr10:65140242ENST000005429210252066_207002359.0MotifNote=LXXLL motif
TgeneJMJD1Cchr7:152522207chr10:65140242ENST000003992510251846_18710477.0Zinc fingerC6-type
TgeneJMJD1Cchr7:152522207chr10:65140242ENST000003992620261846_1871562541.0Zinc fingerC6-type
TgeneJMJD1Cchr7:152522207chr10:65140242ENST000005429210251846_187102359.0Zinc fingerC6-type

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


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Fusion Gene Sequence for ACTR3B-JMJD1C


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>1845_1845_1_ACTR3B-JMJD1C_ACTR3B_chr7_152522207_ENST00000256001_JMJD1C_chr10_65140242_ENST00000399262_length(transcript)=9364nt_BP=1085nt
AGCATCCGGGCTCCCGGCAGCGGCGCTGCGGCGGCTCGCGGGAGACGCTGCGCGCGGGGCTAGCGGGCGGCGGAGCGGACGGCGACGGGG
CGCTCTCGGGCTGCCGGCGGGGCCGAGCGCCGCGCGTCCCGAGCATGGCAGGCTCCCTGCCTCCCTGCGTGGTGGACTGTGGCACCGGGT
ATACCAAGCTTGGCTACGCAGGCAACACTGAGCCCCAGTTCATTATTCCTTCATGTATTGCCATCAGAGAGTCAGCAAAGGTAGTTGACC
AAGCTCAAAGGAGAGTGTTGAGGGGAGTTGATGACCTTGACTTTTTCATAGGAGATGAAGCCATCGATAAACCTACATATGCTACAAAGT
GGCCGATACGACATGGAATCATTGAAGACTGGGATCTTATGGAAAGGTTCATGGAGCAAGTGGTTTTTAAATATCTTCGAGCTGAACCTG
AGGACCATTATTTTTTAATGACAGAACCTCCACTCAATACACCAGAAAACAGAGAGTATCTTGCAGAAATTATGTTTGAATCATTTAACG
TACCAGGACTCTACATTGCAGTTCAGGCAGTGCTGGCCTTGGCGGCATCTTGGACATCTCGACAAGTGGGTGAACGTACGTTAACGGGGA
TAGTCATTGACAGCGGAGATGGAGTCACCCATGTTATCCCAGTGGCAGAAGGTTATGTAATTGGAAGCTGCATCAAACACATCCCGATTG
CAGGTAGAGATATTACGTATTTCATTCAACAGCTGCTAAGGGAGAGGGAGGTGGGAATCCCTCCTGAGCAGTCACTGGAGACCGCAAAAG
CCATTAAGGAGAAATACTGTTACATTTGCCCCGATATAGTCAAGGAATTTGCCAAGTATGATGTGGATCCCCGGAAGTGGATCAAACAGT
ACACGGGTATCAATGCGATCAACCAGAAGAAGTTTGTTATAGACGTTGGTTACGAAAGATTCCTGGGACCTGAAATATTCTTTCACCCGG
AGTTTGCCAACCCAGACTTTATGGAGTCCATCTCAGATGTTGTTGATGAAGTAATACAGAACTGCCCCATCGATGTGCGGCGCCCGCTGT
ATAAGGTGTATGTGGAATTTGATGATCTTGAATGGGATAAACGAGAGTGGGTTAAAGTTTATGAAGATTTTTCAACTTTCTTGGTGGAAT
ACCACTTAATCTGGGCCAAAAGGAATGACCCTAGCCAGACTCAGGGATCAAAGAGCAAACAGATTCAGTGGCCTGCATTGACTTTCAAAC
CTCTGGTTGAAAGAAATATACCCAGTTCAGTCACTGCAGTAGAATTCCTTGTAGATAAGCAACTGGATTTTTTAACTGAAGATAGTGCCT
TTCAGCCCTACCAGGACGACATAGACAGCCTAAACCCAGTTCTCAGGGACAACCCGCAGCTTCATGAGGAAGTGAAAGTCTGGGTAAAGG
AACAAAAGGTTCAGGAGATTTTTATGCAAGGTCCTTATTCCTTAAATGGATACAGAGTGAGAGTATATAGACAAGACTCTGCCACCCAGT
GGTTTACTGGCATAATTACTCATCATGATCTCTTCACCCGCACCATGATCGTTATGAATGATCAGGTACTAGAACCACAGAATGTCGATC
CTTCTATGGTTCAAATGACCTTTCTAGATGATGTTGTTCACTCTTTGTTAAAAGGTGAAAATATTGGCATTACATCACGACGCAGGTCTC
GTGCCAATCAAAACGTCAACGCTGTTCACAGCCATTATACACGTGCCCAAGCAAATAGTCCCAGACCAGCAATGAACTCCCAAGCTGCTG
TACCAAAACAGAATACACACCAGCAACAGCAACAAAGAAGTATCCGTCCAAATAAGAGGAAGGGCTCAGATAGCAGTATACCAGATGAAG
AGAAGATGAAGGAGGAAAAATATGATTATATATCACGAGGAGAAAATCCTAAAGGTAAAAACAAACACTTGATGAATAAAAGAAGGAAAC
CTGAGGAGGATGAAAAGAAACTAAATATGAAAAGACTTCGAACTGACAATGTTTCAGACTTTTCTGAGAGCAGTGACTCAGAAAATTCAA
ATAAGAGAATAATAGATAATTCCTCAGAACAGAAGCCAGAGAATGAATTGAAAAATAAAAATACTTCAAAAATAAATGGAGAAGAAGGAA
AACCCCATAATAATGAGAAGGCAGGAGAAGAGACCCTAAAAAATAGCCAGCCTCCCTGGGATCAAATACAGGAAGATAAAAAACATGAAG
AAGCAGAGAAGCGGAAGTCTGTTGACACTCAGCTTCAAGAAGATATGATTATTCATTCGTCAGAACAGTCCACAGTTTCTGATCATAATT
CTAATGATTTACTTCCTCAGGAATGCAATATGGATAAAACACATACCATGGAATTGCTACCAAAGGAGAAGTTTGTATCCAGACCACCCA
CACCAAAATGTGTTATTGATATTACAAATGACACTAATTTAGAAAAGGTGGCTCAGGAAAACTCAAGTACCTTTGGCCTTCAGACACTTC
AGAAAATGGATCCTAATGTTAGTGATTCAAAACACTCTATTGCAAATGCAAAATTCTTGGAAACAGCAAAAAAAGATTCTGACCAGAGCT
GGGTCAGTGATGTAGTTAAAGTGGATCTAACCCAATCAAGTGTTACAAATGCTTCTTCAGGAAATGATCACTTGAACATGGAAAAAGAGA
AGTATGTCTCTTACATTTCTCCTTTAAGTGCAGTTTCTGTCATGGAAGATAAGCTGCATAAGCGAAGTCCACCTCCAGAGACTATAAAAT
CTAAACTTAATACTTCAGTAGATACTCACAAGATAAAATCCAGCCCATCACCTGAAGTTGTTAAACCCAAAATAACTCATTCTCCTGATT
CTGTAAAGTCTAAGGCCACTTATGTGAACAGCCAAGCTACTGGTGAAAGAAGATTGGCAAATAAGATAGAACATGAGCTATCAAGATGCA
GTTTTCATCCAATTCCTACTCGAAGCAGTACATTAGAAACTACAAAGAGTCCTCTTATCATTGATAAAAATGAGCATTTTACAGTTTACA
GAGATCCTGCACTTATTGGGTCAGAAACAGGAGCTAATCATATTTCACCTTTCCTAAGCCAGCATCCTTTTCCTCTTCACTCCTCATCTC
ATAGAACCTGTTTAAATCCAGGTACCCATCATCCTGCCTTAACTCCTGCACCCCATTTACTAGCCGGATCATCTAGTCAAACTCCATTAC
CTACCATTAACACTCATCCTCTGACTAGTGGTCCACACCATGCTGTTCATCACCCTCATTTACTTCCCACTGTGTTACCTGGAGTGCCTA
CTGCCTCCTTACTTGGTGGCCACCCACGACTAGAGAGTGCTCATGCCAGCAGCTTGAGCCACTTAGCGCTAGCACACCAGCAACAACAAC
AGTTGTTACAGCACCAGTCACCTCATCTTCTTGGACAAGCCCATCCTTCTGCTTCATATAATCAGCTTGGACTTTATCCAATTATTTGGC
AGTATCCAAATGGAACACATGCATACTCAGGACTTGGTTTGCCTTCTTCTAAGTGGGTTCACCCAGAAAATGCAGTTAATGCTGAAGCTT
CATTAAGGAGGAATTCTCCCAGTCCTTGGCTACATCAGCCCACCCCTGTGACCTCAGCAGATGGTATTGGATTACTTAGTCACATTCCTG
TCAGACCTTCCAGTGCAGAGCCTCATCGGCCTCTTAAAATTACAGCCCATTCCAGTCCACCATTGACAAAAACTTTAGTAGATCATCATA
AGGAAGAATTAGAAAGAAAAGCTTTTATGGAACCATTACGGTCTGTTGCATCCACATCAGCCAAAAATGACCTGGATCTAAATAGGTCAC
AGACTGGAAAAGATTGTCACTTACATAGGCATTTTGTGGATCCAGTATTAAATCAGTTACAGAGGCCACCCCAGGAGACTGGAGAGAGGT
TAAACAAATACAAAGAGGAACACCGTCGAATTCTTCAAGAAAGTATTGATGTTGCTCCCTTTACAACTAAAATCAAGGGACTTGAGGGTG
AGAGAGAGAATTATTCCAGAGTGGCATCATCATCTTCCAGTCCTAAAAGCCATATCATCAAACAAGATATGGATGTAGAACGCTCAGTAT
CAGATCTTTATAAAATGAAGCACTCAGTGCCTCAGAGTTTACCCCAAAGTAACTATTTCACTACATTGTCTAATAGTGTGGTCAATGAAC
CACCAAGATCATACCCATCCAAAGAAGTTTCAAATATTTACGGTGATAAACAGAGTAATGCCCTTGCAGCGGCAGCAGCTAATCCTCAAA
CTCTGACTTCATTTATAACATCTCTTTCAAAGCCTCCACCTTTGATTAAACACCAACCAGAAAGTGAAGGTTTAGTAGGCAAGATACCAG
AACATCTTCCACATCAGATTGCATCTCACTCAGTAACAACCTTCAGAAATGATTGTAGGAGTCCTACCCATTTGACAGTTTCTTCTACAA
ATACACTCCGCAGTATGCCTGCATTACATAGAGCACCAGTATTTCACCCACCAATCCATCACAGCCTGGAAAGAAAGGAAGGCAGCTATA
GTAGTCTTTCCCCTCCAACTTTAACTCCGGTGATGCCAGTAAATGCTGGTGGTAAAGTTCAAGAATCACAGAAGCCTCCAACTCTAATAC
CCGAACCAAAAGACTCCCAGGCAAATTTTAAGAGTTCTTCAGAACAGAGTTTGACGGAGATGTGGAGACCTAATAATAACCTCAGCAAAG
AGAAAACTGAATGGCATGTGGAGAAAAGCAGCGGAAAGTTACAGGCTGCTATGGCATCTGTCATTGTGCGTCCATCTTCTAGTACAAAAA
CTGATAGTATGCCAGCAATGCAGTTAGCTTCTAAAGATCGTGTTAGTGAAAGATCTTCAGCTGGGGCACATAAAACAGATTGCCTCAAAC
TAGCAGAAGCCGGAGAAACTGGAAGAATCATTTTGCCAAATGTGAATTCAGACAGTGTTCACACAAAATCTGAAAAAAACTTTCAGGCTG
TCTCACAGGGCAGTGTTCCCAGTTCAGTCATGTCTGCTGTAAATACGATGTGTAATACCAAAACGGATGTAATCACATCTGCTGCCGATA
CTACCAGTGTTTCCAGCTGGGGTGGTTCAGAAGTAATTTCCTCTTTATCAAATACCATTTTGGCCTCTACATCATCAGAATGTGTATCTT
CAAAAAGTGTCAGTCAGCCAGTGGCTCAAAAACAAGAATGCAAGGTCAGCACCACAGCACCAGTTACATTAGCCAGTAGTAAGACAGGAA
GTGTTGTTCAACCCAGTTCTGGGTTCTCAGGCACAACTGATTTTATCCATTTAAAAAAGCACAAGGCAGCATTGGCTGCAGCTCAGTATA
AAAGTAGTAATGCCAGTGAGACTGAACCTAATGCTATAAAAAATCAGACACTTTCAGCCTCCCTTCCTCTGGATAGCACTGTAATCTGTA
GTACAATTAACAAAGCAAACTCTGTAGGAAATGGGCAAGCTTCCCAGACAAGTCAACCAAACTACCATACTAAACTGAAAAAGGCCTGGC
TCACCAGACACTCAGAAGAAGATAAAAATACTAATAAAATGGAAAATTCAGGGAATTCTGTATCAGAAATTATTAAGCCATGTTCTGTCA
ACTTAATAGCCTCTACATCTAGTGATATACAAAATAGTGTAGATAGTAAGATCATAGTTGATAAATATGTAAAAGATGATAAAGTCAACA
GGAGAAAAGCCAAAAGAACTTATGAATCTGGCTCTGAAAGTGGAGACTCAGATGAAAGTGAAAGCAAGTCAGAGCAAAGGACTAAAAGAC
AACCTAAGCCAACTTACAAAAAGAAGCAAAATGATTTGCAAAAGAGAAAAGGTGAAATAGAAGAAGATTTGAAACCCAATGGAGTTCTCA
GCAGGAGTGCCAAAGAAAGAAGTAAACTGAAGTTGCAAAGCAACAGTAATACTGGCATTCCTCGTTCAGTATTGAAAGATTGGCGTAAAG
TCAAGAAGCTGAAGCAAACTGGGGAATCCTTTTTACAGGATGACTCCTGCTGTGAGATAGGGCCTAATTTACAAAAGTGTCGAGAATGTA
GACTTATTCGCAGTAAAAAAGGAGAAGAACCAGCTCACTCACCAGTATTTTGTAGATTTTACTACTTTAGACGGTTGTCATTTAGTAAAA
ACGGAGTAGTTAGAATAGATGGTTTCTCTTCTCCTGACCAATATGATGATGAAGCTATGAGTTTGTGGACACATGAAAATTTTGAAGATG
ATGAACTAGATATAGAGACTTCTAAATATATCTTGGATATAATAGGTGATAAGTTCTGTCAATTAGTAACATCTGAAAAAACAGCTTTGT
CCTGGGTGAAAAAGGATGCCAAAATTGCCTGGAAAAGAGCAGTGAGAGGAGTCCGGGAGATGTGTGATGCATGTGAAGCAACATTGTTTA
ACATTCACTGGGTCTGCCAAAAATGTGGATTTGTGGTCTGCTTAGATTGTTACAAGGCAAAGGAAAGGAAGAGTTCTAGAGATAAAGAAC
TATATGCTTGGATGAAGTGTGTGAAGGGACAGCCTCATGATCACAAACATTTAATGCCAACCCAAATTATACCTGGTTCTGTTTTGACAG
ATCTTCTAGATGCCATGCACACTCTTAGGGAAAAATATGGTATTAAATCCCATTGTCATTGTACTAACAAACAGAATTTACAAGTTGGAA
ATTTTCCTACAATGAATGGTGTATCTCAAGTTTTACAGAATGTTCTTAATCACAGTAATAAAATTTCTCTGTGCATGCCTGAGTCTCAGC
AGCAAAATACTCCTCCGAAGTCTGAGAAAAATGGTGGCAGCAGCCCAGAGAGTGATGTAGGCACAGATAACAAGTTAACTCCTCCAGAAT
CCCAGTCACCACTGCACTGGTTAGCAGATCTTGCAGAGCAAAAAGCCAGAGAGGAAAAAAAAGAAAACAAAGAACTTACCCTTGAAAACC
AAATTAAAGAAGAAAGAGAACAAGACAACTCTGAATCTCCAAATGGCAGAACATCACCTCTTGTGTCCCAGAATAATGAACAAGGCTCAA
CCTTACGGGATTTGCTGACTACAACAGCTGGAAAGCTACGTGTGGGGTCTACAGATGCTGGCATTGCCTTTGCCCCAGTATATTCAATGG
GAGCCCCAAGTAGCAAAAGTGGACGGACTATGCCTAACATTCTTGATGACATAATTGCTTCAGTTGTTGAAAACAAAATTCCACCAAGTA
AAACCTCCAAGATAAATGTAAAACCAGAGCTTAAAGAAGAGCCTGAAGAAAGCATAATATCTGCAGTGGATGAAAATAATAAATTATACA
GTGATATACCACATTCTTGGATCTGTGAGAAGCATATTTTATGGCTTAAGGATTATAAGAATAGCAGTAATTGGAAGCTTTTCAAAGAAT
GTTGGAAACAAGGACAGCCTGCAGTGGTTTCTGGTGTGCATAAGAAAATGAACATTAGCCTATGGAAGGCGGAATCAATTAGTCTTGATT
TTGGAGACCACCAAGCTGATCTCCTGAACTGCAAAGATAGCATCATTTCAAATGCCAATGTTAAGGAATTCTGGGATGGTTTTGAAGAAG
TTTCAAAACGGCAGAAAAACAAGAGTGGAGAAACAGTTGTTTTAAAATTGAAAGACTGGCCTTCAGGAGAAGACTTCAAGACTATGATGC
CAGCAAGATACGAAGATCTTTTAAAAAGTCTGCCATTGCCAGAATATTGTAATCCAGAAGGAAAATTCAATTTGGCCTCTCATTTGCCAG
GATTTTTTGTACGTCCTGATCTAGGACCCAGGTTGTGCAGTGCCTATGGTGTAGTTGCTGCTAAAGATCATGATATAGGAACAACAAATC
TCCATATTGAAGTTTCTGATGTTGTAAATATACTAGTTTATGTTGGCATAGCAAAAGGAAATGGCATTCTCTCAAAAGCAGGAATTCTCA
AGAAATTTGAGGAAGAAGATTTGGATGACATTTTAAGGAAAAGATTGAAGGACTCAAGTGAAATACCTGGTGCTCTGTGGCATATTTATG
CTGGGAAAGATGTTGACAAGATAAGGGAATTTCTTCAAAAGATTTCAAAAGAACAAGGCCTTGAAGTTCTACCAGAACATGATCCAATAC
GTGACCAAAGTTGGTATGTGAACAAAAAGCTCCGTCAAAGGCTGCTTGAAGAATATGGAGTCAGAACCTGTACTCTTATTCAGTTCCTTG
GTGATGCTATTGTTTTGCCAGCGGGAGCACTTCATCAGGTTCAGAATTTTCACAGCTGTATTCAGGTAACTGAAGATTTTGTGTCTCCAG
AACATCTTGTAGAGTCATTTCATTTAACACAGGAACTGAGACTTTTGAAGGAAGAAATCAATTATGATGATAAACTACAGGTTAAAAATA
TTTTGTATCATGCAGTCAAAGAAATGGTGAGAGCCTTGAAGATACACGAGGATGAAGTAGAGGATATGGAAGAAAATTAAGTGTGATCCA
GTTTGATATTTTTAGGTTGTTGAACTGGGATTACTTAACCTTGAATGATGATATGTATGCACACTGACTTTAAGCTTCATAAAACCATCA
GTGCCAAGAAATTCTCTTTGTAGTAATTACTTGTTACTGACACCACAGCAGTATAGCATATGTCACAGCTCCTGTGATTCAATGTTATAA
AACAAGCAGAATTTTAAAAGCAGCACTATATAGCTGTTTTGTATTATAGTGTATATGATGTTTGTGAAAATGCCAGATTTAAAATGATGT
ATTTATTTTTGGTAAAAAATAAAAAATTCTATGCTATATTGTTGATCAAGTGTAAATGTGACCTTGTACAGTTTACTAAAATTACTGATA
TTTTTCACTACATTGAGACAGTTACTGTGAGAATAGGACACAAACACCAGCTATTGCCTGCATCTGGGAAATTGCTGAATCGCACAGCAG
TCATGTCATAATCAGAAAATTACTGCCAAATAATTGTAAAATTTGTAAAGTATAAAGTATATAAAGTAGATACTAAATACAGACACTTCA
ATATTTTGTTGAAGCTATTGACTGTACAATTAAACATTTTCAAAAGGTGTAATTTATTTAAAATTGTCTCATTTTGGTAAAATTTATGTG
AACTTTTAAAGCTAAATATTAAACTTAATATGCTATGTAAATATATACATATATACATTTAATGATGTATTTTTTTAAAACATTGGCTTG
CTTTTGTTAAAGTGCAAGTGTTACATATGGCTTTGTACATTAAAGTTGAAAGGGGTTTTACATTTTCCATTAAAAGGACTTTATCAAAAA

>1845_1845_1_ACTR3B-JMJD1C_ACTR3B_chr7_152522207_ENST00000256001_JMJD1C_chr10_65140242_ENST00000399262_length(amino acids)=2830AA_BP=346
MRAGLAGGGADGDGALSGCRRGRAPRVPSMAGSLPPCVVDCGTGYTKLGYAGNTEPQFIIPSCIAIRESAKVVDQAQRRVLRGVDDLDFF
IGDEAIDKPTYATKWPIRHGIIEDWDLMERFMEQVVFKYLRAEPEDHYFLMTEPPLNTPENREYLAEIMFESFNVPGLYIAVQAVLALAA
SWTSRQVGERTLTGIVIDSGDGVTHVIPVAEGYVIGSCIKHIPIAGRDITYFIQQLLREREVGIPPEQSLETAKAIKEKYCYICPDIVKE
FAKYDVDPRKWIKQYTGINAINQKKFVIDVGYERFLGPEIFFHPEFANPDFMESISDVVDEVIQNCPIDVRRPLYKVYVEFDDLEWDKRE
WVKVYEDFSTFLVEYHLIWAKRNDPSQTQGSKSKQIQWPALTFKPLVERNIPSSVTAVEFLVDKQLDFLTEDSAFQPYQDDIDSLNPVLR
DNPQLHEEVKVWVKEQKVQEIFMQGPYSLNGYRVRVYRQDSATQWFTGIITHHDLFTRTMIVMNDQVLEPQNVDPSMVQMTFLDDVVHSL
LKGENIGITSRRRSRANQNVNAVHSHYTRAQANSPRPAMNSQAAVPKQNTHQQQQQRSIRPNKRKGSDSSIPDEEKMKEEKYDYISRGEN
PKGKNKHLMNKRRKPEEDEKKLNMKRLRTDNVSDFSESSDSENSNKRIIDNSSEQKPENELKNKNTSKINGEEGKPHNNEKAGEETLKNS
QPPWDQIQEDKKHEEAEKRKSVDTQLQEDMIIHSSEQSTVSDHNSNDLLPQECNMDKTHTMELLPKEKFVSRPPTPKCVIDITNDTNLEK
VAQENSSTFGLQTLQKMDPNVSDSKHSIANAKFLETAKKDSDQSWVSDVVKVDLTQSSVTNASSGNDHLNMEKEKYVSYISPLSAVSVME
DKLHKRSPPPETIKSKLNTSVDTHKIKSSPSPEVVKPKITHSPDSVKSKATYVNSQATGERRLANKIEHELSRCSFHPIPTRSSTLETTK
SPLIIDKNEHFTVYRDPALIGSETGANHISPFLSQHPFPLHSSSHRTCLNPGTHHPALTPAPHLLAGSSSQTPLPTINTHPLTSGPHHAV
HHPHLLPTVLPGVPTASLLGGHPRLESAHASSLSHLALAHQQQQQLLQHQSPHLLGQAHPSASYNQLGLYPIIWQYPNGTHAYSGLGLPS
SKWVHPENAVNAEASLRRNSPSPWLHQPTPVTSADGIGLLSHIPVRPSSAEPHRPLKITAHSSPPLTKTLVDHHKEELERKAFMEPLRSV
ASTSAKNDLDLNRSQTGKDCHLHRHFVDPVLNQLQRPPQETGERLNKYKEEHRRILQESIDVAPFTTKIKGLEGERENYSRVASSSSSPK
SHIIKQDMDVERSVSDLYKMKHSVPQSLPQSNYFTTLSNSVVNEPPRSYPSKEVSNIYGDKQSNALAAAAANPQTLTSFITSLSKPPPLI
KHQPESEGLVGKIPEHLPHQIASHSVTTFRNDCRSPTHLTVSSTNTLRSMPALHRAPVFHPPIHHSLERKEGSYSSLSPPTLTPVMPVNA
GGKVQESQKPPTLIPEPKDSQANFKSSSEQSLTEMWRPNNNLSKEKTEWHVEKSSGKLQAAMASVIVRPSSSTKTDSMPAMQLASKDRVS
ERSSAGAHKTDCLKLAEAGETGRIILPNVNSDSVHTKSEKNFQAVSQGSVPSSVMSAVNTMCNTKTDVITSAADTTSVSSWGGSEVISSL
SNTILASTSSECVSSKSVSQPVAQKQECKVSTTAPVTLASSKTGSVVQPSSGFSGTTDFIHLKKHKAALAAAQYKSSNASETEPNAIKNQ
TLSASLPLDSTVICSTINKANSVGNGQASQTSQPNYHTKLKKAWLTRHSEEDKNTNKMENSGNSVSEIIKPCSVNLIASTSSDIQNSVDS
KIIVDKYVKDDKVNRRKAKRTYESGSESGDSDESESKSEQRTKRQPKPTYKKKQNDLQKRKGEIEEDLKPNGVLSRSAKERSKLKLQSNS
NTGIPRSVLKDWRKVKKLKQTGESFLQDDSCCEIGPNLQKCRECRLIRSKKGEEPAHSPVFCRFYYFRRLSFSKNGVVRIDGFSSPDQYD
DEAMSLWTHENFEDDELDIETSKYILDIIGDKFCQLVTSEKTALSWVKKDAKIAWKRAVRGVREMCDACEATLFNIHWVCQKCGFVVCLD
CYKAKERKSSRDKELYAWMKCVKGQPHDHKHLMPTQIIPGSVLTDLLDAMHTLREKYGIKSHCHCTNKQNLQVGNFPTMNGVSQVLQNVL
NHSNKISLCMPESQQQNTPPKSEKNGGSSPESDVGTDNKLTPPESQSPLHWLADLAEQKAREEKKENKELTLENQIKEEREQDNSESPNG
RTSPLVSQNNEQGSTLRDLLTTTAGKLRVGSTDAGIAFAPVYSMGAPSSKSGRTMPNILDDIIASVVENKIPPSKTSKINVKPELKEEPE
ESIISAVDENNKLYSDIPHSWICEKHILWLKDYKNSSNWKLFKECWKQGQPAVVSGVHKKMNISLWKAESISLDFGDHQADLLNCKDSII
SNANVKEFWDGFEEVSKRQKNKSGETVVLKLKDWPSGEDFKTMMPARYEDLLKSLPLPEYCNPEGKFNLASHLPGFFVRPDLGPRLCSAY
GVVAAKDHDIGTTNLHIEVSDVVNILVYVGIAKGNGILSKAGILKKFEEEDLDDILRKRLKDSSEIPGALWHIYAGKDVDKIREFLQKIS
KEQGLEVLPEHDPIRDQSWYVNKKLRQRLLEEYGVRTCTLIQFLGDAIVLPAGALHQVQNFHSCIQVTEDFVSPEHLVESFHLTQELRLL

--------------------------------------------------------------
>1845_1845_2_ACTR3B-JMJD1C_ACTR3B_chr7_152522207_ENST00000377776_JMJD1C_chr10_65140242_ENST00000399262_length(transcript)=9364nt_BP=1085nt
AGCATCCGGGCTCCCGGCAGCGGCGCTGCGGCGGCTCGCGGGAGACGCTGCGCGCGGGGCTAGCGGGCGGCGGAGCGGACGGCGACGGGG
CGCTCTCGGGCTGCCGGCGGGGCCGAGCGCCGCGCGTCCCGAGCATGGCAGGCTCCCTGCCTCCCTGCGTGGTGGACTGTGGCACCGGGT
ATACCAAGCTTGGCTACGCAGGCAACACTGAGCCCCAGTTCATTATTCCTTCATGTATTGCCATCAGAGAGTCAGCAAAGGTAGTTGACC
AAGCTCAAAGGAGAGTGTTGAGGGGAGTTGATGACCTTGACTTTTTCATAGGAGATGAAGCCATCGATAAACCTACATATGCTACAAAGT
GGCCGATACGACATGGAATCATTGAAGACTGGGATCTTATGGAAAGGTTCATGGAGCAAGTGGTTTTTAAATATCTTCGAGCTGAACCTG
AGGACCATTATTTTTTAATGACAGAACCTCCACTCAATACACCAGAAAACAGAGAGTATCTTGCAGAAATTATGTTTGAATCATTTAACG
TACCAGGACTCTACATTGCAGTTCAGGCAGTGCTGGCCTTGGCGGCATCTTGGACATCTCGACAAGTGGGTGAACGTACGTTAACGGGGA
TAGTCATTGACAGCGGAGATGGAGTCACCCATGTTATCCCAGTGGCAGAAGGTTATGTAATTGGAAGCTGCATCAAACACATCCCGATTG
CAGGTAGAGATATTACGTATTTCATTCAACAGCTGCTAAGGGAGAGGGAGGTGGGAATCCCTCCTGAGCAGTCACTGGAGACCGCAAAAG
CCATTAAGGAGAAATACTGTTACATTTGCCCCGATATAGTCAAGGAATTTGCCAAGTATGATGTGGATCCCCGGAAGTGGATCAAACAGT
ACACGGGTATCAATGCGATCAACCAGAAGAAGTTTGTTATAGACGTTGGTTACGAAAGATTCCTGGGACCTGAAATATTCTTTCACCCGG
AGTTTGCCAACCCAGACTTTATGGAGTCCATCTCAGATGTTGTTGATGAAGTAATACAGAACTGCCCCATCGATGTGCGGCGCCCGCTGT
ATAAGGTGTATGTGGAATTTGATGATCTTGAATGGGATAAACGAGAGTGGGTTAAAGTTTATGAAGATTTTTCAACTTTCTTGGTGGAAT
ACCACTTAATCTGGGCCAAAAGGAATGACCCTAGCCAGACTCAGGGATCAAAGAGCAAACAGATTCAGTGGCCTGCATTGACTTTCAAAC
CTCTGGTTGAAAGAAATATACCCAGTTCAGTCACTGCAGTAGAATTCCTTGTAGATAAGCAACTGGATTTTTTAACTGAAGATAGTGCCT
TTCAGCCCTACCAGGACGACATAGACAGCCTAAACCCAGTTCTCAGGGACAACCCGCAGCTTCATGAGGAAGTGAAAGTCTGGGTAAAGG
AACAAAAGGTTCAGGAGATTTTTATGCAAGGTCCTTATTCCTTAAATGGATACAGAGTGAGAGTATATAGACAAGACTCTGCCACCCAGT
GGTTTACTGGCATAATTACTCATCATGATCTCTTCACCCGCACCATGATCGTTATGAATGATCAGGTACTAGAACCACAGAATGTCGATC
CTTCTATGGTTCAAATGACCTTTCTAGATGATGTTGTTCACTCTTTGTTAAAAGGTGAAAATATTGGCATTACATCACGACGCAGGTCTC
GTGCCAATCAAAACGTCAACGCTGTTCACAGCCATTATACACGTGCCCAAGCAAATAGTCCCAGACCAGCAATGAACTCCCAAGCTGCTG
TACCAAAACAGAATACACACCAGCAACAGCAACAAAGAAGTATCCGTCCAAATAAGAGGAAGGGCTCAGATAGCAGTATACCAGATGAAG
AGAAGATGAAGGAGGAAAAATATGATTATATATCACGAGGAGAAAATCCTAAAGGTAAAAACAAACACTTGATGAATAAAAGAAGGAAAC
CTGAGGAGGATGAAAAGAAACTAAATATGAAAAGACTTCGAACTGACAATGTTTCAGACTTTTCTGAGAGCAGTGACTCAGAAAATTCAA
ATAAGAGAATAATAGATAATTCCTCAGAACAGAAGCCAGAGAATGAATTGAAAAATAAAAATACTTCAAAAATAAATGGAGAAGAAGGAA
AACCCCATAATAATGAGAAGGCAGGAGAAGAGACCCTAAAAAATAGCCAGCCTCCCTGGGATCAAATACAGGAAGATAAAAAACATGAAG
AAGCAGAGAAGCGGAAGTCTGTTGACACTCAGCTTCAAGAAGATATGATTATTCATTCGTCAGAACAGTCCACAGTTTCTGATCATAATT
CTAATGATTTACTTCCTCAGGAATGCAATATGGATAAAACACATACCATGGAATTGCTACCAAAGGAGAAGTTTGTATCCAGACCACCCA
CACCAAAATGTGTTATTGATATTACAAATGACACTAATTTAGAAAAGGTGGCTCAGGAAAACTCAAGTACCTTTGGCCTTCAGACACTTC
AGAAAATGGATCCTAATGTTAGTGATTCAAAACACTCTATTGCAAATGCAAAATTCTTGGAAACAGCAAAAAAAGATTCTGACCAGAGCT
GGGTCAGTGATGTAGTTAAAGTGGATCTAACCCAATCAAGTGTTACAAATGCTTCTTCAGGAAATGATCACTTGAACATGGAAAAAGAGA
AGTATGTCTCTTACATTTCTCCTTTAAGTGCAGTTTCTGTCATGGAAGATAAGCTGCATAAGCGAAGTCCACCTCCAGAGACTATAAAAT
CTAAACTTAATACTTCAGTAGATACTCACAAGATAAAATCCAGCCCATCACCTGAAGTTGTTAAACCCAAAATAACTCATTCTCCTGATT
CTGTAAAGTCTAAGGCCACTTATGTGAACAGCCAAGCTACTGGTGAAAGAAGATTGGCAAATAAGATAGAACATGAGCTATCAAGATGCA
GTTTTCATCCAATTCCTACTCGAAGCAGTACATTAGAAACTACAAAGAGTCCTCTTATCATTGATAAAAATGAGCATTTTACAGTTTACA
GAGATCCTGCACTTATTGGGTCAGAAACAGGAGCTAATCATATTTCACCTTTCCTAAGCCAGCATCCTTTTCCTCTTCACTCCTCATCTC
ATAGAACCTGTTTAAATCCAGGTACCCATCATCCTGCCTTAACTCCTGCACCCCATTTACTAGCCGGATCATCTAGTCAAACTCCATTAC
CTACCATTAACACTCATCCTCTGACTAGTGGTCCACACCATGCTGTTCATCACCCTCATTTACTTCCCACTGTGTTACCTGGAGTGCCTA
CTGCCTCCTTACTTGGTGGCCACCCACGACTAGAGAGTGCTCATGCCAGCAGCTTGAGCCACTTAGCGCTAGCACACCAGCAACAACAAC
AGTTGTTACAGCACCAGTCACCTCATCTTCTTGGACAAGCCCATCCTTCTGCTTCATATAATCAGCTTGGACTTTATCCAATTATTTGGC
AGTATCCAAATGGAACACATGCATACTCAGGACTTGGTTTGCCTTCTTCTAAGTGGGTTCACCCAGAAAATGCAGTTAATGCTGAAGCTT
CATTAAGGAGGAATTCTCCCAGTCCTTGGCTACATCAGCCCACCCCTGTGACCTCAGCAGATGGTATTGGATTACTTAGTCACATTCCTG
TCAGACCTTCCAGTGCAGAGCCTCATCGGCCTCTTAAAATTACAGCCCATTCCAGTCCACCATTGACAAAAACTTTAGTAGATCATCATA
AGGAAGAATTAGAAAGAAAAGCTTTTATGGAACCATTACGGTCTGTTGCATCCACATCAGCCAAAAATGACCTGGATCTAAATAGGTCAC
AGACTGGAAAAGATTGTCACTTACATAGGCATTTTGTGGATCCAGTATTAAATCAGTTACAGAGGCCACCCCAGGAGACTGGAGAGAGGT
TAAACAAATACAAAGAGGAACACCGTCGAATTCTTCAAGAAAGTATTGATGTTGCTCCCTTTACAACTAAAATCAAGGGACTTGAGGGTG
AGAGAGAGAATTATTCCAGAGTGGCATCATCATCTTCCAGTCCTAAAAGCCATATCATCAAACAAGATATGGATGTAGAACGCTCAGTAT
CAGATCTTTATAAAATGAAGCACTCAGTGCCTCAGAGTTTACCCCAAAGTAACTATTTCACTACATTGTCTAATAGTGTGGTCAATGAAC
CACCAAGATCATACCCATCCAAAGAAGTTTCAAATATTTACGGTGATAAACAGAGTAATGCCCTTGCAGCGGCAGCAGCTAATCCTCAAA
CTCTGACTTCATTTATAACATCTCTTTCAAAGCCTCCACCTTTGATTAAACACCAACCAGAAAGTGAAGGTTTAGTAGGCAAGATACCAG
AACATCTTCCACATCAGATTGCATCTCACTCAGTAACAACCTTCAGAAATGATTGTAGGAGTCCTACCCATTTGACAGTTTCTTCTACAA
ATACACTCCGCAGTATGCCTGCATTACATAGAGCACCAGTATTTCACCCACCAATCCATCACAGCCTGGAAAGAAAGGAAGGCAGCTATA
GTAGTCTTTCCCCTCCAACTTTAACTCCGGTGATGCCAGTAAATGCTGGTGGTAAAGTTCAAGAATCACAGAAGCCTCCAACTCTAATAC
CCGAACCAAAAGACTCCCAGGCAAATTTTAAGAGTTCTTCAGAACAGAGTTTGACGGAGATGTGGAGACCTAATAATAACCTCAGCAAAG
AGAAAACTGAATGGCATGTGGAGAAAAGCAGCGGAAAGTTACAGGCTGCTATGGCATCTGTCATTGTGCGTCCATCTTCTAGTACAAAAA
CTGATAGTATGCCAGCAATGCAGTTAGCTTCTAAAGATCGTGTTAGTGAAAGATCTTCAGCTGGGGCACATAAAACAGATTGCCTCAAAC
TAGCAGAAGCCGGAGAAACTGGAAGAATCATTTTGCCAAATGTGAATTCAGACAGTGTTCACACAAAATCTGAAAAAAACTTTCAGGCTG
TCTCACAGGGCAGTGTTCCCAGTTCAGTCATGTCTGCTGTAAATACGATGTGTAATACCAAAACGGATGTAATCACATCTGCTGCCGATA
CTACCAGTGTTTCCAGCTGGGGTGGTTCAGAAGTAATTTCCTCTTTATCAAATACCATTTTGGCCTCTACATCATCAGAATGTGTATCTT
CAAAAAGTGTCAGTCAGCCAGTGGCTCAAAAACAAGAATGCAAGGTCAGCACCACAGCACCAGTTACATTAGCCAGTAGTAAGACAGGAA
GTGTTGTTCAACCCAGTTCTGGGTTCTCAGGCACAACTGATTTTATCCATTTAAAAAAGCACAAGGCAGCATTGGCTGCAGCTCAGTATA
AAAGTAGTAATGCCAGTGAGACTGAACCTAATGCTATAAAAAATCAGACACTTTCAGCCTCCCTTCCTCTGGATAGCACTGTAATCTGTA
GTACAATTAACAAAGCAAACTCTGTAGGAAATGGGCAAGCTTCCCAGACAAGTCAACCAAACTACCATACTAAACTGAAAAAGGCCTGGC
TCACCAGACACTCAGAAGAAGATAAAAATACTAATAAAATGGAAAATTCAGGGAATTCTGTATCAGAAATTATTAAGCCATGTTCTGTCA
ACTTAATAGCCTCTACATCTAGTGATATACAAAATAGTGTAGATAGTAAGATCATAGTTGATAAATATGTAAAAGATGATAAAGTCAACA
GGAGAAAAGCCAAAAGAACTTATGAATCTGGCTCTGAAAGTGGAGACTCAGATGAAAGTGAAAGCAAGTCAGAGCAAAGGACTAAAAGAC
AACCTAAGCCAACTTACAAAAAGAAGCAAAATGATTTGCAAAAGAGAAAAGGTGAAATAGAAGAAGATTTGAAACCCAATGGAGTTCTCA
GCAGGAGTGCCAAAGAAAGAAGTAAACTGAAGTTGCAAAGCAACAGTAATACTGGCATTCCTCGTTCAGTATTGAAAGATTGGCGTAAAG
TCAAGAAGCTGAAGCAAACTGGGGAATCCTTTTTACAGGATGACTCCTGCTGTGAGATAGGGCCTAATTTACAAAAGTGTCGAGAATGTA
GACTTATTCGCAGTAAAAAAGGAGAAGAACCAGCTCACTCACCAGTATTTTGTAGATTTTACTACTTTAGACGGTTGTCATTTAGTAAAA
ACGGAGTAGTTAGAATAGATGGTTTCTCTTCTCCTGACCAATATGATGATGAAGCTATGAGTTTGTGGACACATGAAAATTTTGAAGATG
ATGAACTAGATATAGAGACTTCTAAATATATCTTGGATATAATAGGTGATAAGTTCTGTCAATTAGTAACATCTGAAAAAACAGCTTTGT
CCTGGGTGAAAAAGGATGCCAAAATTGCCTGGAAAAGAGCAGTGAGAGGAGTCCGGGAGATGTGTGATGCATGTGAAGCAACATTGTTTA
ACATTCACTGGGTCTGCCAAAAATGTGGATTTGTGGTCTGCTTAGATTGTTACAAGGCAAAGGAAAGGAAGAGTTCTAGAGATAAAGAAC
TATATGCTTGGATGAAGTGTGTGAAGGGACAGCCTCATGATCACAAACATTTAATGCCAACCCAAATTATACCTGGTTCTGTTTTGACAG
ATCTTCTAGATGCCATGCACACTCTTAGGGAAAAATATGGTATTAAATCCCATTGTCATTGTACTAACAAACAGAATTTACAAGTTGGAA
ATTTTCCTACAATGAATGGTGTATCTCAAGTTTTACAGAATGTTCTTAATCACAGTAATAAAATTTCTCTGTGCATGCCTGAGTCTCAGC
AGCAAAATACTCCTCCGAAGTCTGAGAAAAATGGTGGCAGCAGCCCAGAGAGTGATGTAGGCACAGATAACAAGTTAACTCCTCCAGAAT
CCCAGTCACCACTGCACTGGTTAGCAGATCTTGCAGAGCAAAAAGCCAGAGAGGAAAAAAAAGAAAACAAAGAACTTACCCTTGAAAACC
AAATTAAAGAAGAAAGAGAACAAGACAACTCTGAATCTCCAAATGGCAGAACATCACCTCTTGTGTCCCAGAATAATGAACAAGGCTCAA
CCTTACGGGATTTGCTGACTACAACAGCTGGAAAGCTACGTGTGGGGTCTACAGATGCTGGCATTGCCTTTGCCCCAGTATATTCAATGG
GAGCCCCAAGTAGCAAAAGTGGACGGACTATGCCTAACATTCTTGATGACATAATTGCTTCAGTTGTTGAAAACAAAATTCCACCAAGTA
AAACCTCCAAGATAAATGTAAAACCAGAGCTTAAAGAAGAGCCTGAAGAAAGCATAATATCTGCAGTGGATGAAAATAATAAATTATACA
GTGATATACCACATTCTTGGATCTGTGAGAAGCATATTTTATGGCTTAAGGATTATAAGAATAGCAGTAATTGGAAGCTTTTCAAAGAAT
GTTGGAAACAAGGACAGCCTGCAGTGGTTTCTGGTGTGCATAAGAAAATGAACATTAGCCTATGGAAGGCGGAATCAATTAGTCTTGATT
TTGGAGACCACCAAGCTGATCTCCTGAACTGCAAAGATAGCATCATTTCAAATGCCAATGTTAAGGAATTCTGGGATGGTTTTGAAGAAG
TTTCAAAACGGCAGAAAAACAAGAGTGGAGAAACAGTTGTTTTAAAATTGAAAGACTGGCCTTCAGGAGAAGACTTCAAGACTATGATGC
CAGCAAGATACGAAGATCTTTTAAAAAGTCTGCCATTGCCAGAATATTGTAATCCAGAAGGAAAATTCAATTTGGCCTCTCATTTGCCAG
GATTTTTTGTACGTCCTGATCTAGGACCCAGGTTGTGCAGTGCCTATGGTGTAGTTGCTGCTAAAGATCATGATATAGGAACAACAAATC
TCCATATTGAAGTTTCTGATGTTGTAAATATACTAGTTTATGTTGGCATAGCAAAAGGAAATGGCATTCTCTCAAAAGCAGGAATTCTCA
AGAAATTTGAGGAAGAAGATTTGGATGACATTTTAAGGAAAAGATTGAAGGACTCAAGTGAAATACCTGGTGCTCTGTGGCATATTTATG
CTGGGAAAGATGTTGACAAGATAAGGGAATTTCTTCAAAAGATTTCAAAAGAACAAGGCCTTGAAGTTCTACCAGAACATGATCCAATAC
GTGACCAAAGTTGGTATGTGAACAAAAAGCTCCGTCAAAGGCTGCTTGAAGAATATGGAGTCAGAACCTGTACTCTTATTCAGTTCCTTG
GTGATGCTATTGTTTTGCCAGCGGGAGCACTTCATCAGGTTCAGAATTTTCACAGCTGTATTCAGGTAACTGAAGATTTTGTGTCTCCAG
AACATCTTGTAGAGTCATTTCATTTAACACAGGAACTGAGACTTTTGAAGGAAGAAATCAATTATGATGATAAACTACAGGTTAAAAATA
TTTTGTATCATGCAGTCAAAGAAATGGTGAGAGCCTTGAAGATACACGAGGATGAAGTAGAGGATATGGAAGAAAATTAAGTGTGATCCA
GTTTGATATTTTTAGGTTGTTGAACTGGGATTACTTAACCTTGAATGATGATATGTATGCACACTGACTTTAAGCTTCATAAAACCATCA
GTGCCAAGAAATTCTCTTTGTAGTAATTACTTGTTACTGACACCACAGCAGTATAGCATATGTCACAGCTCCTGTGATTCAATGTTATAA
AACAAGCAGAATTTTAAAAGCAGCACTATATAGCTGTTTTGTATTATAGTGTATATGATGTTTGTGAAAATGCCAGATTTAAAATGATGT
ATTTATTTTTGGTAAAAAATAAAAAATTCTATGCTATATTGTTGATCAAGTGTAAATGTGACCTTGTACAGTTTACTAAAATTACTGATA
TTTTTCACTACATTGAGACAGTTACTGTGAGAATAGGACACAAACACCAGCTATTGCCTGCATCTGGGAAATTGCTGAATCGCACAGCAG
TCATGTCATAATCAGAAAATTACTGCCAAATAATTGTAAAATTTGTAAAGTATAAAGTATATAAAGTAGATACTAAATACAGACACTTCA
ATATTTTGTTGAAGCTATTGACTGTACAATTAAACATTTTCAAAAGGTGTAATTTATTTAAAATTGTCTCATTTTGGTAAAATTTATGTG
AACTTTTAAAGCTAAATATTAAACTTAATATGCTATGTAAATATATACATATATACATTTAATGATGTATTTTTTTAAAACATTGGCTTG
CTTTTGTTAAAGTGCAAGTGTTACATATGGCTTTGTACATTAAAGTTGAAAGGGGTTTTACATTTTCCATTAAAAGGACTTTATCAAAAA

>1845_1845_2_ACTR3B-JMJD1C_ACTR3B_chr7_152522207_ENST00000377776_JMJD1C_chr10_65140242_ENST00000399262_length(amino acids)=2830AA_BP=346
MRAGLAGGGADGDGALSGCRRGRAPRVPSMAGSLPPCVVDCGTGYTKLGYAGNTEPQFIIPSCIAIRESAKVVDQAQRRVLRGVDDLDFF
IGDEAIDKPTYATKWPIRHGIIEDWDLMERFMEQVVFKYLRAEPEDHYFLMTEPPLNTPENREYLAEIMFESFNVPGLYIAVQAVLALAA
SWTSRQVGERTLTGIVIDSGDGVTHVIPVAEGYVIGSCIKHIPIAGRDITYFIQQLLREREVGIPPEQSLETAKAIKEKYCYICPDIVKE
FAKYDVDPRKWIKQYTGINAINQKKFVIDVGYERFLGPEIFFHPEFANPDFMESISDVVDEVIQNCPIDVRRPLYKVYVEFDDLEWDKRE
WVKVYEDFSTFLVEYHLIWAKRNDPSQTQGSKSKQIQWPALTFKPLVERNIPSSVTAVEFLVDKQLDFLTEDSAFQPYQDDIDSLNPVLR
DNPQLHEEVKVWVKEQKVQEIFMQGPYSLNGYRVRVYRQDSATQWFTGIITHHDLFTRTMIVMNDQVLEPQNVDPSMVQMTFLDDVVHSL
LKGENIGITSRRRSRANQNVNAVHSHYTRAQANSPRPAMNSQAAVPKQNTHQQQQQRSIRPNKRKGSDSSIPDEEKMKEEKYDYISRGEN
PKGKNKHLMNKRRKPEEDEKKLNMKRLRTDNVSDFSESSDSENSNKRIIDNSSEQKPENELKNKNTSKINGEEGKPHNNEKAGEETLKNS
QPPWDQIQEDKKHEEAEKRKSVDTQLQEDMIIHSSEQSTVSDHNSNDLLPQECNMDKTHTMELLPKEKFVSRPPTPKCVIDITNDTNLEK
VAQENSSTFGLQTLQKMDPNVSDSKHSIANAKFLETAKKDSDQSWVSDVVKVDLTQSSVTNASSGNDHLNMEKEKYVSYISPLSAVSVME
DKLHKRSPPPETIKSKLNTSVDTHKIKSSPSPEVVKPKITHSPDSVKSKATYVNSQATGERRLANKIEHELSRCSFHPIPTRSSTLETTK
SPLIIDKNEHFTVYRDPALIGSETGANHISPFLSQHPFPLHSSSHRTCLNPGTHHPALTPAPHLLAGSSSQTPLPTINTHPLTSGPHHAV
HHPHLLPTVLPGVPTASLLGGHPRLESAHASSLSHLALAHQQQQQLLQHQSPHLLGQAHPSASYNQLGLYPIIWQYPNGTHAYSGLGLPS
SKWVHPENAVNAEASLRRNSPSPWLHQPTPVTSADGIGLLSHIPVRPSSAEPHRPLKITAHSSPPLTKTLVDHHKEELERKAFMEPLRSV
ASTSAKNDLDLNRSQTGKDCHLHRHFVDPVLNQLQRPPQETGERLNKYKEEHRRILQESIDVAPFTTKIKGLEGERENYSRVASSSSSPK
SHIIKQDMDVERSVSDLYKMKHSVPQSLPQSNYFTTLSNSVVNEPPRSYPSKEVSNIYGDKQSNALAAAAANPQTLTSFITSLSKPPPLI
KHQPESEGLVGKIPEHLPHQIASHSVTTFRNDCRSPTHLTVSSTNTLRSMPALHRAPVFHPPIHHSLERKEGSYSSLSPPTLTPVMPVNA
GGKVQESQKPPTLIPEPKDSQANFKSSSEQSLTEMWRPNNNLSKEKTEWHVEKSSGKLQAAMASVIVRPSSSTKTDSMPAMQLASKDRVS
ERSSAGAHKTDCLKLAEAGETGRIILPNVNSDSVHTKSEKNFQAVSQGSVPSSVMSAVNTMCNTKTDVITSAADTTSVSSWGGSEVISSL
SNTILASTSSECVSSKSVSQPVAQKQECKVSTTAPVTLASSKTGSVVQPSSGFSGTTDFIHLKKHKAALAAAQYKSSNASETEPNAIKNQ
TLSASLPLDSTVICSTINKANSVGNGQASQTSQPNYHTKLKKAWLTRHSEEDKNTNKMENSGNSVSEIIKPCSVNLIASTSSDIQNSVDS
KIIVDKYVKDDKVNRRKAKRTYESGSESGDSDESESKSEQRTKRQPKPTYKKKQNDLQKRKGEIEEDLKPNGVLSRSAKERSKLKLQSNS
NTGIPRSVLKDWRKVKKLKQTGESFLQDDSCCEIGPNLQKCRECRLIRSKKGEEPAHSPVFCRFYYFRRLSFSKNGVVRIDGFSSPDQYD
DEAMSLWTHENFEDDELDIETSKYILDIIGDKFCQLVTSEKTALSWVKKDAKIAWKRAVRGVREMCDACEATLFNIHWVCQKCGFVVCLD
CYKAKERKSSRDKELYAWMKCVKGQPHDHKHLMPTQIIPGSVLTDLLDAMHTLREKYGIKSHCHCTNKQNLQVGNFPTMNGVSQVLQNVL
NHSNKISLCMPESQQQNTPPKSEKNGGSSPESDVGTDNKLTPPESQSPLHWLADLAEQKAREEKKENKELTLENQIKEEREQDNSESPNG
RTSPLVSQNNEQGSTLRDLLTTTAGKLRVGSTDAGIAFAPVYSMGAPSSKSGRTMPNILDDIIASVVENKIPPSKTSKINVKPELKEEPE
ESIISAVDENNKLYSDIPHSWICEKHILWLKDYKNSSNWKLFKECWKQGQPAVVSGVHKKMNISLWKAESISLDFGDHQADLLNCKDSII
SNANVKEFWDGFEEVSKRQKNKSGETVVLKLKDWPSGEDFKTMMPARYEDLLKSLPLPEYCNPEGKFNLASHLPGFFVRPDLGPRLCSAY
GVVAAKDHDIGTTNLHIEVSDVVNILVYVGIAKGNGILSKAGILKKFEEEDLDDILRKRLKDSSEIPGALWHIYAGKDVDKIREFLQKIS
KEQGLEVLPEHDPIRDQSWYVNKKLRQRLLEEYGVRTCTLIQFLGDAIVLPAGALHQVQNFHSCIQVTEDFVSPEHLVESFHLTQELRLL

--------------------------------------------------------------
>1845_1845_3_ACTR3B-JMJD1C_ACTR3B_chr7_152522207_ENST00000397282_JMJD1C_chr10_65140242_ENST00000399262_length(transcript)=9269nt_BP=990nt
GGGAGACGCTGCGCGCGGGGCTAGCGGGCGGCGGAGCGGACGGCGACGGGGCGCTCTCGGGCTGCCGGCGGGGCCGAGCGCCGCGCGTCC
CGAGCATGGCAGGCTCCCTGCCTCCCTGCGTGGTGGACTGTGGCACCGGGTATTGCCATCAGAGAGTCAGCAAAGGTAGTTGACCAAGCT
CAAAGGAGAGTGTTGAGGGGAGTTGATGACCTTGACTTTTTCATAGGAGATGAAGCCATCGATAAACCTACATATGCTACAAAGTGGCCG
ATACGACATGGAATCATTGAAGACTGGGATCTTATGGAAAGGTTCATGGAGCAAGTGGTTTTTAAATATCTTCGAGCTGAACCTGAGGAC
CATTATTTTTTAATGACAGAACCTCCACTCAATACACCAGAAAACAGAGAGTATCTTGCAGAAATTATGTTTGAATCATTTAACGTACCA
GGACTCTACATTGCAGTTCAGGCAGTGCTGGCCTTGGCGGCATCTTGGACATCTCGACAAGTGGGTGAACGTACGTTAACGGGGATAGTC
ATTGACAGCGGAGATGGAGTCACCCATGTTATCCCAGTGGCAGAAGGTTATGTAATTGGAAGCTGCATCAAACACATCCCGATTGCAGGT
AGAGATATTACGTATTTCATTCAACAGCTGCTAAGGGAGAGGGAGGTGGGAATCCCTCCTGAGCAGTCACTGGAGACCGCAAAAGCCATT
AAGGAGAAATACTGTTACATTTGCCCCGATATAGTCAAGGAATTTGCCAAGTATGATGTGGATCCCCGGAAGTGGATCAAACAGTACACG
GGTATCAATGCGATCAACCAGAAGAAGTTTGTTATAGACGTTGGTTACGAAAGATTCCTGGGACCTGAAATATTCTTTCACCCGGAGTTT
GCCAACCCAGACTTTATGGAGTCCATCTCAGATGTTGTTGATGAAGTAATACAGAACTGCCCCATCGATGTGCGGCGCCCGCTGTATAAG
GTGTATGTGGAATTTGATGATCTTGAATGGGATAAACGAGAGTGGGTTAAAGTTTATGAAGATTTTTCAACTTTCTTGGTGGAATACCAC
TTAATCTGGGCCAAAAGGAATGACCCTAGCCAGACTCAGGGATCAAAGAGCAAACAGATTCAGTGGCCTGCATTGACTTTCAAACCTCTG
GTTGAAAGAAATATACCCAGTTCAGTCACTGCAGTAGAATTCCTTGTAGATAAGCAACTGGATTTTTTAACTGAAGATAGTGCCTTTCAG
CCCTACCAGGACGACATAGACAGCCTAAACCCAGTTCTCAGGGACAACCCGCAGCTTCATGAGGAAGTGAAAGTCTGGGTAAAGGAACAA
AAGGTTCAGGAGATTTTTATGCAAGGTCCTTATTCCTTAAATGGATACAGAGTGAGAGTATATAGACAAGACTCTGCCACCCAGTGGTTT
ACTGGCATAATTACTCATCATGATCTCTTCACCCGCACCATGATCGTTATGAATGATCAGGTACTAGAACCACAGAATGTCGATCCTTCT
ATGGTTCAAATGACCTTTCTAGATGATGTTGTTCACTCTTTGTTAAAAGGTGAAAATATTGGCATTACATCACGACGCAGGTCTCGTGCC
AATCAAAACGTCAACGCTGTTCACAGCCATTATACACGTGCCCAAGCAAATAGTCCCAGACCAGCAATGAACTCCCAAGCTGCTGTACCA
AAACAGAATACACACCAGCAACAGCAACAAAGAAGTATCCGTCCAAATAAGAGGAAGGGCTCAGATAGCAGTATACCAGATGAAGAGAAG
ATGAAGGAGGAAAAATATGATTATATATCACGAGGAGAAAATCCTAAAGGTAAAAACAAACACTTGATGAATAAAAGAAGGAAACCTGAG
GAGGATGAAAAGAAACTAAATATGAAAAGACTTCGAACTGACAATGTTTCAGACTTTTCTGAGAGCAGTGACTCAGAAAATTCAAATAAG
AGAATAATAGATAATTCCTCAGAACAGAAGCCAGAGAATGAATTGAAAAATAAAAATACTTCAAAAATAAATGGAGAAGAAGGAAAACCC
CATAATAATGAGAAGGCAGGAGAAGAGACCCTAAAAAATAGCCAGCCTCCCTGGGATCAAATACAGGAAGATAAAAAACATGAAGAAGCA
GAGAAGCGGAAGTCTGTTGACACTCAGCTTCAAGAAGATATGATTATTCATTCGTCAGAACAGTCCACAGTTTCTGATCATAATTCTAAT
GATTTACTTCCTCAGGAATGCAATATGGATAAAACACATACCATGGAATTGCTACCAAAGGAGAAGTTTGTATCCAGACCACCCACACCA
AAATGTGTTATTGATATTACAAATGACACTAATTTAGAAAAGGTGGCTCAGGAAAACTCAAGTACCTTTGGCCTTCAGACACTTCAGAAA
ATGGATCCTAATGTTAGTGATTCAAAACACTCTATTGCAAATGCAAAATTCTTGGAAACAGCAAAAAAAGATTCTGACCAGAGCTGGGTC
AGTGATGTAGTTAAAGTGGATCTAACCCAATCAAGTGTTACAAATGCTTCTTCAGGAAATGATCACTTGAACATGGAAAAAGAGAAGTAT
GTCTCTTACATTTCTCCTTTAAGTGCAGTTTCTGTCATGGAAGATAAGCTGCATAAGCGAAGTCCACCTCCAGAGACTATAAAATCTAAA
CTTAATACTTCAGTAGATACTCACAAGATAAAATCCAGCCCATCACCTGAAGTTGTTAAACCCAAAATAACTCATTCTCCTGATTCTGTA
AAGTCTAAGGCCACTTATGTGAACAGCCAAGCTACTGGTGAAAGAAGATTGGCAAATAAGATAGAACATGAGCTATCAAGATGCAGTTTT
CATCCAATTCCTACTCGAAGCAGTACATTAGAAACTACAAAGAGTCCTCTTATCATTGATAAAAATGAGCATTTTACAGTTTACAGAGAT
CCTGCACTTATTGGGTCAGAAACAGGAGCTAATCATATTTCACCTTTCCTAAGCCAGCATCCTTTTCCTCTTCACTCCTCATCTCATAGA
ACCTGTTTAAATCCAGGTACCCATCATCCTGCCTTAACTCCTGCACCCCATTTACTAGCCGGATCATCTAGTCAAACTCCATTACCTACC
ATTAACACTCATCCTCTGACTAGTGGTCCACACCATGCTGTTCATCACCCTCATTTACTTCCCACTGTGTTACCTGGAGTGCCTACTGCC
TCCTTACTTGGTGGCCACCCACGACTAGAGAGTGCTCATGCCAGCAGCTTGAGCCACTTAGCGCTAGCACACCAGCAACAACAACAGTTG
TTACAGCACCAGTCACCTCATCTTCTTGGACAAGCCCATCCTTCTGCTTCATATAATCAGCTTGGACTTTATCCAATTATTTGGCAGTAT
CCAAATGGAACACATGCATACTCAGGACTTGGTTTGCCTTCTTCTAAGTGGGTTCACCCAGAAAATGCAGTTAATGCTGAAGCTTCATTA
AGGAGGAATTCTCCCAGTCCTTGGCTACATCAGCCCACCCCTGTGACCTCAGCAGATGGTATTGGATTACTTAGTCACATTCCTGTCAGA
CCTTCCAGTGCAGAGCCTCATCGGCCTCTTAAAATTACAGCCCATTCCAGTCCACCATTGACAAAAACTTTAGTAGATCATCATAAGGAA
GAATTAGAAAGAAAAGCTTTTATGGAACCATTACGGTCTGTTGCATCCACATCAGCCAAAAATGACCTGGATCTAAATAGGTCACAGACT
GGAAAAGATTGTCACTTACATAGGCATTTTGTGGATCCAGTATTAAATCAGTTACAGAGGCCACCCCAGGAGACTGGAGAGAGGTTAAAC
AAATACAAAGAGGAACACCGTCGAATTCTTCAAGAAAGTATTGATGTTGCTCCCTTTACAACTAAAATCAAGGGACTTGAGGGTGAGAGA
GAGAATTATTCCAGAGTGGCATCATCATCTTCCAGTCCTAAAAGCCATATCATCAAACAAGATATGGATGTAGAACGCTCAGTATCAGAT
CTTTATAAAATGAAGCACTCAGTGCCTCAGAGTTTACCCCAAAGTAACTATTTCACTACATTGTCTAATAGTGTGGTCAATGAACCACCA
AGATCATACCCATCCAAAGAAGTTTCAAATATTTACGGTGATAAACAGAGTAATGCCCTTGCAGCGGCAGCAGCTAATCCTCAAACTCTG
ACTTCATTTATAACATCTCTTTCAAAGCCTCCACCTTTGATTAAACACCAACCAGAAAGTGAAGGTTTAGTAGGCAAGATACCAGAACAT
CTTCCACATCAGATTGCATCTCACTCAGTAACAACCTTCAGAAATGATTGTAGGAGTCCTACCCATTTGACAGTTTCTTCTACAAATACA
CTCCGCAGTATGCCTGCATTACATAGAGCACCAGTATTTCACCCACCAATCCATCACAGCCTGGAAAGAAAGGAAGGCAGCTATAGTAGT
CTTTCCCCTCCAACTTTAACTCCGGTGATGCCAGTAAATGCTGGTGGTAAAGTTCAAGAATCACAGAAGCCTCCAACTCTAATACCCGAA
CCAAAAGACTCCCAGGCAAATTTTAAGAGTTCTTCAGAACAGAGTTTGACGGAGATGTGGAGACCTAATAATAACCTCAGCAAAGAGAAA
ACTGAATGGCATGTGGAGAAAAGCAGCGGAAAGTTACAGGCTGCTATGGCATCTGTCATTGTGCGTCCATCTTCTAGTACAAAAACTGAT
AGTATGCCAGCAATGCAGTTAGCTTCTAAAGATCGTGTTAGTGAAAGATCTTCAGCTGGGGCACATAAAACAGATTGCCTCAAACTAGCA
GAAGCCGGAGAAACTGGAAGAATCATTTTGCCAAATGTGAATTCAGACAGTGTTCACACAAAATCTGAAAAAAACTTTCAGGCTGTCTCA
CAGGGCAGTGTTCCCAGTTCAGTCATGTCTGCTGTAAATACGATGTGTAATACCAAAACGGATGTAATCACATCTGCTGCCGATACTACC
AGTGTTTCCAGCTGGGGTGGTTCAGAAGTAATTTCCTCTTTATCAAATACCATTTTGGCCTCTACATCATCAGAATGTGTATCTTCAAAA
AGTGTCAGTCAGCCAGTGGCTCAAAAACAAGAATGCAAGGTCAGCACCACAGCACCAGTTACATTAGCCAGTAGTAAGACAGGAAGTGTT
GTTCAACCCAGTTCTGGGTTCTCAGGCACAACTGATTTTATCCATTTAAAAAAGCACAAGGCAGCATTGGCTGCAGCTCAGTATAAAAGT
AGTAATGCCAGTGAGACTGAACCTAATGCTATAAAAAATCAGACACTTTCAGCCTCCCTTCCTCTGGATAGCACTGTAATCTGTAGTACA
ATTAACAAAGCAAACTCTGTAGGAAATGGGCAAGCTTCCCAGACAAGTCAACCAAACTACCATACTAAACTGAAAAAGGCCTGGCTCACC
AGACACTCAGAAGAAGATAAAAATACTAATAAAATGGAAAATTCAGGGAATTCTGTATCAGAAATTATTAAGCCATGTTCTGTCAACTTA
ATAGCCTCTACATCTAGTGATATACAAAATAGTGTAGATAGTAAGATCATAGTTGATAAATATGTAAAAGATGATAAAGTCAACAGGAGA
AAAGCCAAAAGAACTTATGAATCTGGCTCTGAAAGTGGAGACTCAGATGAAAGTGAAAGCAAGTCAGAGCAAAGGACTAAAAGACAACCT
AAGCCAACTTACAAAAAGAAGCAAAATGATTTGCAAAAGAGAAAAGGTGAAATAGAAGAAGATTTGAAACCCAATGGAGTTCTCAGCAGG
AGTGCCAAAGAAAGAAGTAAACTGAAGTTGCAAAGCAACAGTAATACTGGCATTCCTCGTTCAGTATTGAAAGATTGGCGTAAAGTCAAG
AAGCTGAAGCAAACTGGGGAATCCTTTTTACAGGATGACTCCTGCTGTGAGATAGGGCCTAATTTACAAAAGTGTCGAGAATGTAGACTT
ATTCGCAGTAAAAAAGGAGAAGAACCAGCTCACTCACCAGTATTTTGTAGATTTTACTACTTTAGACGGTTGTCATTTAGTAAAAACGGA
GTAGTTAGAATAGATGGTTTCTCTTCTCCTGACCAATATGATGATGAAGCTATGAGTTTGTGGACACATGAAAATTTTGAAGATGATGAA
CTAGATATAGAGACTTCTAAATATATCTTGGATATAATAGGTGATAAGTTCTGTCAATTAGTAACATCTGAAAAAACAGCTTTGTCCTGG
GTGAAAAAGGATGCCAAAATTGCCTGGAAAAGAGCAGTGAGAGGAGTCCGGGAGATGTGTGATGCATGTGAAGCAACATTGTTTAACATT
CACTGGGTCTGCCAAAAATGTGGATTTGTGGTCTGCTTAGATTGTTACAAGGCAAAGGAAAGGAAGAGTTCTAGAGATAAAGAACTATAT
GCTTGGATGAAGTGTGTGAAGGGACAGCCTCATGATCACAAACATTTAATGCCAACCCAAATTATACCTGGTTCTGTTTTGACAGATCTT
CTAGATGCCATGCACACTCTTAGGGAAAAATATGGTATTAAATCCCATTGTCATTGTACTAACAAACAGAATTTACAAGTTGGAAATTTT
CCTACAATGAATGGTGTATCTCAAGTTTTACAGAATGTTCTTAATCACAGTAATAAAATTTCTCTGTGCATGCCTGAGTCTCAGCAGCAA
AATACTCCTCCGAAGTCTGAGAAAAATGGTGGCAGCAGCCCAGAGAGTGATGTAGGCACAGATAACAAGTTAACTCCTCCAGAATCCCAG
TCACCACTGCACTGGTTAGCAGATCTTGCAGAGCAAAAAGCCAGAGAGGAAAAAAAAGAAAACAAAGAACTTACCCTTGAAAACCAAATT
AAAGAAGAAAGAGAACAAGACAACTCTGAATCTCCAAATGGCAGAACATCACCTCTTGTGTCCCAGAATAATGAACAAGGCTCAACCTTA
CGGGATTTGCTGACTACAACAGCTGGAAAGCTACGTGTGGGGTCTACAGATGCTGGCATTGCCTTTGCCCCAGTATATTCAATGGGAGCC
CCAAGTAGCAAAAGTGGACGGACTATGCCTAACATTCTTGATGACATAATTGCTTCAGTTGTTGAAAACAAAATTCCACCAAGTAAAACC
TCCAAGATAAATGTAAAACCAGAGCTTAAAGAAGAGCCTGAAGAAAGCATAATATCTGCAGTGGATGAAAATAATAAATTATACAGTGAT
ATACCACATTCTTGGATCTGTGAGAAGCATATTTTATGGCTTAAGGATTATAAGAATAGCAGTAATTGGAAGCTTTTCAAAGAATGTTGG
AAACAAGGACAGCCTGCAGTGGTTTCTGGTGTGCATAAGAAAATGAACATTAGCCTATGGAAGGCGGAATCAATTAGTCTTGATTTTGGA
GACCACCAAGCTGATCTCCTGAACTGCAAAGATAGCATCATTTCAAATGCCAATGTTAAGGAATTCTGGGATGGTTTTGAAGAAGTTTCA
AAACGGCAGAAAAACAAGAGTGGAGAAACAGTTGTTTTAAAATTGAAAGACTGGCCTTCAGGAGAAGACTTCAAGACTATGATGCCAGCA
AGATACGAAGATCTTTTAAAAAGTCTGCCATTGCCAGAATATTGTAATCCAGAAGGAAAATTCAATTTGGCCTCTCATTTGCCAGGATTT
TTTGTACGTCCTGATCTAGGACCCAGGTTGTGCAGTGCCTATGGTGTAGTTGCTGCTAAAGATCATGATATAGGAACAACAAATCTCCAT
ATTGAAGTTTCTGATGTTGTAAATATACTAGTTTATGTTGGCATAGCAAAAGGAAATGGCATTCTCTCAAAAGCAGGAATTCTCAAGAAA
TTTGAGGAAGAAGATTTGGATGACATTTTAAGGAAAAGATTGAAGGACTCAAGTGAAATACCTGGTGCTCTGTGGCATATTTATGCTGGG
AAAGATGTTGACAAGATAAGGGAATTTCTTCAAAAGATTTCAAAAGAACAAGGCCTTGAAGTTCTACCAGAACATGATCCAATACGTGAC
CAAAGTTGGTATGTGAACAAAAAGCTCCGTCAAAGGCTGCTTGAAGAATATGGAGTCAGAACCTGTACTCTTATTCAGTTCCTTGGTGAT
GCTATTGTTTTGCCAGCGGGAGCACTTCATCAGGTTCAGAATTTTCACAGCTGTATTCAGGTAACTGAAGATTTTGTGTCTCCAGAACAT
CTTGTAGAGTCATTTCATTTAACACAGGAACTGAGACTTTTGAAGGAAGAAATCAATTATGATGATAAACTACAGGTTAAAAATATTTTG
TATCATGCAGTCAAAGAAATGGTGAGAGCCTTGAAGATACACGAGGATGAAGTAGAGGATATGGAAGAAAATTAAGTGTGATCCAGTTTG
ATATTTTTAGGTTGTTGAACTGGGATTACTTAACCTTGAATGATGATATGTATGCACACTGACTTTAAGCTTCATAAAACCATCAGTGCC
AAGAAATTCTCTTTGTAGTAATTACTTGTTACTGACACCACAGCAGTATAGCATATGTCACAGCTCCTGTGATTCAATGTTATAAAACAA
GCAGAATTTTAAAAGCAGCACTATATAGCTGTTTTGTATTATAGTGTATATGATGTTTGTGAAAATGCCAGATTTAAAATGATGTATTTA
TTTTTGGTAAAAAATAAAAAATTCTATGCTATATTGTTGATCAAGTGTAAATGTGACCTTGTACAGTTTACTAAAATTACTGATATTTTT
CACTACATTGAGACAGTTACTGTGAGAATAGGACACAAACACCAGCTATTGCCTGCATCTGGGAAATTGCTGAATCGCACAGCAGTCATG
TCATAATCAGAAAATTACTGCCAAATAATTGTAAAATTTGTAAAGTATAAAGTATATAAAGTAGATACTAAATACAGACACTTCAATATT
TTGTTGAAGCTATTGACTGTACAATTAAACATTTTCAAAAGGTGTAATTTATTTAAAATTGTCTCATTTTGGTAAAATTTATGTGAACTT
TTAAAGCTAAATATTAAACTTAATATGCTATGTAAATATATACATATATACATTTAATGATGTATTTTTTTAAAACATTGGCTTGCTTTT

>1845_1845_3_ACTR3B-JMJD1C_ACTR3B_chr7_152522207_ENST00000397282_JMJD1C_chr10_65140242_ENST00000399262_length(amino acids)=2750AA_BP=266
MRGVDDLDFFIGDEAIDKPTYATKWPIRHGIIEDWDLMERFMEQVVFKYLRAEPEDHYFLMTEPPLNTPENREYLAEIMFESFNVPGLYI
AVQAVLALAASWTSRQVGERTLTGIVIDSGDGVTHVIPVAEGYVIGSCIKHIPIAGRDITYFIQQLLREREVGIPPEQSLETAKAIKEKY
CYICPDIVKEFAKYDVDPRKWIKQYTGINAINQKKFVIDVGYERFLGPEIFFHPEFANPDFMESISDVVDEVIQNCPIDVRRPLYKVYVE
FDDLEWDKREWVKVYEDFSTFLVEYHLIWAKRNDPSQTQGSKSKQIQWPALTFKPLVERNIPSSVTAVEFLVDKQLDFLTEDSAFQPYQD
DIDSLNPVLRDNPQLHEEVKVWVKEQKVQEIFMQGPYSLNGYRVRVYRQDSATQWFTGIITHHDLFTRTMIVMNDQVLEPQNVDPSMVQM
TFLDDVVHSLLKGENIGITSRRRSRANQNVNAVHSHYTRAQANSPRPAMNSQAAVPKQNTHQQQQQRSIRPNKRKGSDSSIPDEEKMKEE
KYDYISRGENPKGKNKHLMNKRRKPEEDEKKLNMKRLRTDNVSDFSESSDSENSNKRIIDNSSEQKPENELKNKNTSKINGEEGKPHNNE
KAGEETLKNSQPPWDQIQEDKKHEEAEKRKSVDTQLQEDMIIHSSEQSTVSDHNSNDLLPQECNMDKTHTMELLPKEKFVSRPPTPKCVI
DITNDTNLEKVAQENSSTFGLQTLQKMDPNVSDSKHSIANAKFLETAKKDSDQSWVSDVVKVDLTQSSVTNASSGNDHLNMEKEKYVSYI
SPLSAVSVMEDKLHKRSPPPETIKSKLNTSVDTHKIKSSPSPEVVKPKITHSPDSVKSKATYVNSQATGERRLANKIEHELSRCSFHPIP
TRSSTLETTKSPLIIDKNEHFTVYRDPALIGSETGANHISPFLSQHPFPLHSSSHRTCLNPGTHHPALTPAPHLLAGSSSQTPLPTINTH
PLTSGPHHAVHHPHLLPTVLPGVPTASLLGGHPRLESAHASSLSHLALAHQQQQQLLQHQSPHLLGQAHPSASYNQLGLYPIIWQYPNGT
HAYSGLGLPSSKWVHPENAVNAEASLRRNSPSPWLHQPTPVTSADGIGLLSHIPVRPSSAEPHRPLKITAHSSPPLTKTLVDHHKEELER
KAFMEPLRSVASTSAKNDLDLNRSQTGKDCHLHRHFVDPVLNQLQRPPQETGERLNKYKEEHRRILQESIDVAPFTTKIKGLEGERENYS
RVASSSSSPKSHIIKQDMDVERSVSDLYKMKHSVPQSLPQSNYFTTLSNSVVNEPPRSYPSKEVSNIYGDKQSNALAAAAANPQTLTSFI
TSLSKPPPLIKHQPESEGLVGKIPEHLPHQIASHSVTTFRNDCRSPTHLTVSSTNTLRSMPALHRAPVFHPPIHHSLERKEGSYSSLSPP
TLTPVMPVNAGGKVQESQKPPTLIPEPKDSQANFKSSSEQSLTEMWRPNNNLSKEKTEWHVEKSSGKLQAAMASVIVRPSSSTKTDSMPA
MQLASKDRVSERSSAGAHKTDCLKLAEAGETGRIILPNVNSDSVHTKSEKNFQAVSQGSVPSSVMSAVNTMCNTKTDVITSAADTTSVSS
WGGSEVISSLSNTILASTSSECVSSKSVSQPVAQKQECKVSTTAPVTLASSKTGSVVQPSSGFSGTTDFIHLKKHKAALAAAQYKSSNAS
ETEPNAIKNQTLSASLPLDSTVICSTINKANSVGNGQASQTSQPNYHTKLKKAWLTRHSEEDKNTNKMENSGNSVSEIIKPCSVNLIAST
SSDIQNSVDSKIIVDKYVKDDKVNRRKAKRTYESGSESGDSDESESKSEQRTKRQPKPTYKKKQNDLQKRKGEIEEDLKPNGVLSRSAKE
RSKLKLQSNSNTGIPRSVLKDWRKVKKLKQTGESFLQDDSCCEIGPNLQKCRECRLIRSKKGEEPAHSPVFCRFYYFRRLSFSKNGVVRI
DGFSSPDQYDDEAMSLWTHENFEDDELDIETSKYILDIIGDKFCQLVTSEKTALSWVKKDAKIAWKRAVRGVREMCDACEATLFNIHWVC
QKCGFVVCLDCYKAKERKSSRDKELYAWMKCVKGQPHDHKHLMPTQIIPGSVLTDLLDAMHTLREKYGIKSHCHCTNKQNLQVGNFPTMN
GVSQVLQNVLNHSNKISLCMPESQQQNTPPKSEKNGGSSPESDVGTDNKLTPPESQSPLHWLADLAEQKAREEKKENKELTLENQIKEER
EQDNSESPNGRTSPLVSQNNEQGSTLRDLLTTTAGKLRVGSTDAGIAFAPVYSMGAPSSKSGRTMPNILDDIIASVVENKIPPSKTSKIN
VKPELKEEPEESIISAVDENNKLYSDIPHSWICEKHILWLKDYKNSSNWKLFKECWKQGQPAVVSGVHKKMNISLWKAESISLDFGDHQA
DLLNCKDSIISNANVKEFWDGFEEVSKRQKNKSGETVVLKLKDWPSGEDFKTMMPARYEDLLKSLPLPEYCNPEGKFNLASHLPGFFVRP
DLGPRLCSAYGVVAAKDHDIGTTNLHIEVSDVVNILVYVGIAKGNGILSKAGILKKFEEEDLDDILRKRLKDSSEIPGALWHIYAGKDVD
KIREFLQKISKEQGLEVLPEHDPIRDQSWYVNKKLRQRLLEEYGVRTCTLIQFLGDAIVLPAGALHQVQNFHSCIQVTEDFVSPEHLVES

--------------------------------------------------------------
>1845_1845_4_ACTR3B-JMJD1C_ACTR3B_chr7_152522207_ENST00000537264_JMJD1C_chr10_65140242_ENST00000399262_length(transcript)=9159nt_BP=880nt
GGCGACGGGGCGCTCTCGGGCTGCCGGCGGGGCCGAGCGCCGCGCGTCCCGAGCATGGCAGGCTCCCTGCCTCCCTGCGTGGTGGACTGT
GGCACCGGGTATACCAAGCTTGGCTACGCAGGCAACACTGAGCCCCAGTTCATTATTCCTTCATTGGCCGATACGACATGGAATCATTGA
AGACTGGGATCTTATGGAAAGGTTCATGGAGCAAGTGGTTTTTAAATATCTTCGAGCTGAACCTGAGGACCATTATTTTTTAATGACAGA
ACCTCCACTCAATACACCAGAAAACAGAGAGTATCTTGCAGAAATTATGTTTGAATCATTTAACGTACCAGGACTCTACATTGCAGTTCA
GGCAGTGCTGGCCTTGGCGGCATCTTGGACATCTCGACAAGTGGGTGAACGTACGTTAACGGGGATAGTCATTGACAGCGGAGATGGAGT
CACCCATGTTATCCCAGTGGCAGAAGGTTATGTAATTGGAAGCTGCATCAAACACATCCCGATTGCAGGTAGAGATATTACGTATTTCAT
TCAACAGCTGCTAAGGGAGAGGGAGGTGGGAATCCCTCCTGAGCAGTCACTGGAGACCGCAAAAGCCATTAAGGAGAAATACTGTTACAT
TTGCCCCGATATAGTCAAGGAATTTGCCAAGTATGATGTGGATCCCCGGAAGTGGATCAAACAGTACACGGGTATCAATGCGATCAACCA
GAAGAAGTTTGTTATAGACGTTGGTTACGAAAGATTCCTGGGACCTGAAATATTCTTTCACCCGGAGTTTGCCAACCCAGACTTTATGGA
GTCCATCTCAGATGTTGTTGATGAAGTAATACAGAACTGCCCCATCGATGTGCGGCGCCCGCTGTATAAGGTGTATGTGGAATTTGATGA
TCTTGAATGGGATAAACGAGAGTGGGTTAAAGTTTATGAAGATTTTTCAACTTTCTTGGTGGAATACCACTTAATCTGGGCCAAAAGGAA
TGACCCTAGCCAGACTCAGGGATCAAAGAGCAAACAGATTCAGTGGCCTGCATTGACTTTCAAACCTCTGGTTGAAAGAAATATACCCAG
TTCAGTCACTGCAGTAGAATTCCTTGTAGATAAGCAACTGGATTTTTTAACTGAAGATAGTGCCTTTCAGCCCTACCAGGACGACATAGA
CAGCCTAAACCCAGTTCTCAGGGACAACCCGCAGCTTCATGAGGAAGTGAAAGTCTGGGTAAAGGAACAAAAGGTTCAGGAGATTTTTAT
GCAAGGTCCTTATTCCTTAAATGGATACAGAGTGAGAGTATATAGACAAGACTCTGCCACCCAGTGGTTTACTGGCATAATTACTCATCA
TGATCTCTTCACCCGCACCATGATCGTTATGAATGATCAGGTACTAGAACCACAGAATGTCGATCCTTCTATGGTTCAAATGACCTTTCT
AGATGATGTTGTTCACTCTTTGTTAAAAGGTGAAAATATTGGCATTACATCACGACGCAGGTCTCGTGCCAATCAAAACGTCAACGCTGT
TCACAGCCATTATACACGTGCCCAAGCAAATAGTCCCAGACCAGCAATGAACTCCCAAGCTGCTGTACCAAAACAGAATACACACCAGCA
ACAGCAACAAAGAAGTATCCGTCCAAATAAGAGGAAGGGCTCAGATAGCAGTATACCAGATGAAGAGAAGATGAAGGAGGAAAAATATGA
TTATATATCACGAGGAGAAAATCCTAAAGGTAAAAACAAACACTTGATGAATAAAAGAAGGAAACCTGAGGAGGATGAAAAGAAACTAAA
TATGAAAAGACTTCGAACTGACAATGTTTCAGACTTTTCTGAGAGCAGTGACTCAGAAAATTCAAATAAGAGAATAATAGATAATTCCTC
AGAACAGAAGCCAGAGAATGAATTGAAAAATAAAAATACTTCAAAAATAAATGGAGAAGAAGGAAAACCCCATAATAATGAGAAGGCAGG
AGAAGAGACCCTAAAAAATAGCCAGCCTCCCTGGGATCAAATACAGGAAGATAAAAAACATGAAGAAGCAGAGAAGCGGAAGTCTGTTGA
CACTCAGCTTCAAGAAGATATGATTATTCATTCGTCAGAACAGTCCACAGTTTCTGATCATAATTCTAATGATTTACTTCCTCAGGAATG
CAATATGGATAAAACACATACCATGGAATTGCTACCAAAGGAGAAGTTTGTATCCAGACCACCCACACCAAAATGTGTTATTGATATTAC
AAATGACACTAATTTAGAAAAGGTGGCTCAGGAAAACTCAAGTACCTTTGGCCTTCAGACACTTCAGAAAATGGATCCTAATGTTAGTGA
TTCAAAACACTCTATTGCAAATGCAAAATTCTTGGAAACAGCAAAAAAAGATTCTGACCAGAGCTGGGTCAGTGATGTAGTTAAAGTGGA
TCTAACCCAATCAAGTGTTACAAATGCTTCTTCAGGAAATGATCACTTGAACATGGAAAAAGAGAAGTATGTCTCTTACATTTCTCCTTT
AAGTGCAGTTTCTGTCATGGAAGATAAGCTGCATAAGCGAAGTCCACCTCCAGAGACTATAAAATCTAAACTTAATACTTCAGTAGATAC
TCACAAGATAAAATCCAGCCCATCACCTGAAGTTGTTAAACCCAAAATAACTCATTCTCCTGATTCTGTAAAGTCTAAGGCCACTTATGT
GAACAGCCAAGCTACTGGTGAAAGAAGATTGGCAAATAAGATAGAACATGAGCTATCAAGATGCAGTTTTCATCCAATTCCTACTCGAAG
CAGTACATTAGAAACTACAAAGAGTCCTCTTATCATTGATAAAAATGAGCATTTTACAGTTTACAGAGATCCTGCACTTATTGGGTCAGA
AACAGGAGCTAATCATATTTCACCTTTCCTAAGCCAGCATCCTTTTCCTCTTCACTCCTCATCTCATAGAACCTGTTTAAATCCAGGTAC
CCATCATCCTGCCTTAACTCCTGCACCCCATTTACTAGCCGGATCATCTAGTCAAACTCCATTACCTACCATTAACACTCATCCTCTGAC
TAGTGGTCCACACCATGCTGTTCATCACCCTCATTTACTTCCCACTGTGTTACCTGGAGTGCCTACTGCCTCCTTACTTGGTGGCCACCC
ACGACTAGAGAGTGCTCATGCCAGCAGCTTGAGCCACTTAGCGCTAGCACACCAGCAACAACAACAGTTGTTACAGCACCAGTCACCTCA
TCTTCTTGGACAAGCCCATCCTTCTGCTTCATATAATCAGCTTGGACTTTATCCAATTATTTGGCAGTATCCAAATGGAACACATGCATA
CTCAGGACTTGGTTTGCCTTCTTCTAAGTGGGTTCACCCAGAAAATGCAGTTAATGCTGAAGCTTCATTAAGGAGGAATTCTCCCAGTCC
TTGGCTACATCAGCCCACCCCTGTGACCTCAGCAGATGGTATTGGATTACTTAGTCACATTCCTGTCAGACCTTCCAGTGCAGAGCCTCA
TCGGCCTCTTAAAATTACAGCCCATTCCAGTCCACCATTGACAAAAACTTTAGTAGATCATCATAAGGAAGAATTAGAAAGAAAAGCTTT
TATGGAACCATTACGGTCTGTTGCATCCACATCAGCCAAAAATGACCTGGATCTAAATAGGTCACAGACTGGAAAAGATTGTCACTTACA
TAGGCATTTTGTGGATCCAGTATTAAATCAGTTACAGAGGCCACCCCAGGAGACTGGAGAGAGGTTAAACAAATACAAAGAGGAACACCG
TCGAATTCTTCAAGAAAGTATTGATGTTGCTCCCTTTACAACTAAAATCAAGGGACTTGAGGGTGAGAGAGAGAATTATTCCAGAGTGGC
ATCATCATCTTCCAGTCCTAAAAGCCATATCATCAAACAAGATATGGATGTAGAACGCTCAGTATCAGATCTTTATAAAATGAAGCACTC
AGTGCCTCAGAGTTTACCCCAAAGTAACTATTTCACTACATTGTCTAATAGTGTGGTCAATGAACCACCAAGATCATACCCATCCAAAGA
AGTTTCAAATATTTACGGTGATAAACAGAGTAATGCCCTTGCAGCGGCAGCAGCTAATCCTCAAACTCTGACTTCATTTATAACATCTCT
TTCAAAGCCTCCACCTTTGATTAAACACCAACCAGAAAGTGAAGGTTTAGTAGGCAAGATACCAGAACATCTTCCACATCAGATTGCATC
TCACTCAGTAACAACCTTCAGAAATGATTGTAGGAGTCCTACCCATTTGACAGTTTCTTCTACAAATACACTCCGCAGTATGCCTGCATT
ACATAGAGCACCAGTATTTCACCCACCAATCCATCACAGCCTGGAAAGAAAGGAAGGCAGCTATAGTAGTCTTTCCCCTCCAACTTTAAC
TCCGGTGATGCCAGTAAATGCTGGTGGTAAAGTTCAAGAATCACAGAAGCCTCCAACTCTAATACCCGAACCAAAAGACTCCCAGGCAAA
TTTTAAGAGTTCTTCAGAACAGAGTTTGACGGAGATGTGGAGACCTAATAATAACCTCAGCAAAGAGAAAACTGAATGGCATGTGGAGAA
AAGCAGCGGAAAGTTACAGGCTGCTATGGCATCTGTCATTGTGCGTCCATCTTCTAGTACAAAAACTGATAGTATGCCAGCAATGCAGTT
AGCTTCTAAAGATCGTGTTAGTGAAAGATCTTCAGCTGGGGCACATAAAACAGATTGCCTCAAACTAGCAGAAGCCGGAGAAACTGGAAG
AATCATTTTGCCAAATGTGAATTCAGACAGTGTTCACACAAAATCTGAAAAAAACTTTCAGGCTGTCTCACAGGGCAGTGTTCCCAGTTC
AGTCATGTCTGCTGTAAATACGATGTGTAATACCAAAACGGATGTAATCACATCTGCTGCCGATACTACCAGTGTTTCCAGCTGGGGTGG
TTCAGAAGTAATTTCCTCTTTATCAAATACCATTTTGGCCTCTACATCATCAGAATGTGTATCTTCAAAAAGTGTCAGTCAGCCAGTGGC
TCAAAAACAAGAATGCAAGGTCAGCACCACAGCACCAGTTACATTAGCCAGTAGTAAGACAGGAAGTGTTGTTCAACCCAGTTCTGGGTT
CTCAGGCACAACTGATTTTATCCATTTAAAAAAGCACAAGGCAGCATTGGCTGCAGCTCAGTATAAAAGTAGTAATGCCAGTGAGACTGA
ACCTAATGCTATAAAAAATCAGACACTTTCAGCCTCCCTTCCTCTGGATAGCACTGTAATCTGTAGTACAATTAACAAAGCAAACTCTGT
AGGAAATGGGCAAGCTTCCCAGACAAGTCAACCAAACTACCATACTAAACTGAAAAAGGCCTGGCTCACCAGACACTCAGAAGAAGATAA
AAATACTAATAAAATGGAAAATTCAGGGAATTCTGTATCAGAAATTATTAAGCCATGTTCTGTCAACTTAATAGCCTCTACATCTAGTGA
TATACAAAATAGTGTAGATAGTAAGATCATAGTTGATAAATATGTAAAAGATGATAAAGTCAACAGGAGAAAAGCCAAAAGAACTTATGA
ATCTGGCTCTGAAAGTGGAGACTCAGATGAAAGTGAAAGCAAGTCAGAGCAAAGGACTAAAAGACAACCTAAGCCAACTTACAAAAAGAA
GCAAAATGATTTGCAAAAGAGAAAAGGTGAAATAGAAGAAGATTTGAAACCCAATGGAGTTCTCAGCAGGAGTGCCAAAGAAAGAAGTAA
ACTGAAGTTGCAAAGCAACAGTAATACTGGCATTCCTCGTTCAGTATTGAAAGATTGGCGTAAAGTCAAGAAGCTGAAGCAAACTGGGGA
ATCCTTTTTACAGGATGACTCCTGCTGTGAGATAGGGCCTAATTTACAAAAGTGTCGAGAATGTAGACTTATTCGCAGTAAAAAAGGAGA
AGAACCAGCTCACTCACCAGTATTTTGTAGATTTTACTACTTTAGACGGTTGTCATTTAGTAAAAACGGAGTAGTTAGAATAGATGGTTT
CTCTTCTCCTGACCAATATGATGATGAAGCTATGAGTTTGTGGACACATGAAAATTTTGAAGATGATGAACTAGATATAGAGACTTCTAA
ATATATCTTGGATATAATAGGTGATAAGTTCTGTCAATTAGTAACATCTGAAAAAACAGCTTTGTCCTGGGTGAAAAAGGATGCCAAAAT
TGCCTGGAAAAGAGCAGTGAGAGGAGTCCGGGAGATGTGTGATGCATGTGAAGCAACATTGTTTAACATTCACTGGGTCTGCCAAAAATG
TGGATTTGTGGTCTGCTTAGATTGTTACAAGGCAAAGGAAAGGAAGAGTTCTAGAGATAAAGAACTATATGCTTGGATGAAGTGTGTGAA
GGGACAGCCTCATGATCACAAACATTTAATGCCAACCCAAATTATACCTGGTTCTGTTTTGACAGATCTTCTAGATGCCATGCACACTCT
TAGGGAAAAATATGGTATTAAATCCCATTGTCATTGTACTAACAAACAGAATTTACAAGTTGGAAATTTTCCTACAATGAATGGTGTATC
TCAAGTTTTACAGAATGTTCTTAATCACAGTAATAAAATTTCTCTGTGCATGCCTGAGTCTCAGCAGCAAAATACTCCTCCGAAGTCTGA
GAAAAATGGTGGCAGCAGCCCAGAGAGTGATGTAGGCACAGATAACAAGTTAACTCCTCCAGAATCCCAGTCACCACTGCACTGGTTAGC
AGATCTTGCAGAGCAAAAAGCCAGAGAGGAAAAAAAAGAAAACAAAGAACTTACCCTTGAAAACCAAATTAAAGAAGAAAGAGAACAAGA
CAACTCTGAATCTCCAAATGGCAGAACATCACCTCTTGTGTCCCAGAATAATGAACAAGGCTCAACCTTACGGGATTTGCTGACTACAAC
AGCTGGAAAGCTACGTGTGGGGTCTACAGATGCTGGCATTGCCTTTGCCCCAGTATATTCAATGGGAGCCCCAAGTAGCAAAAGTGGACG
GACTATGCCTAACATTCTTGATGACATAATTGCTTCAGTTGTTGAAAACAAAATTCCACCAAGTAAAACCTCCAAGATAAATGTAAAACC
AGAGCTTAAAGAAGAGCCTGAAGAAAGCATAATATCTGCAGTGGATGAAAATAATAAATTATACAGTGATATACCACATTCTTGGATCTG
TGAGAAGCATATTTTATGGCTTAAGGATTATAAGAATAGCAGTAATTGGAAGCTTTTCAAAGAATGTTGGAAACAAGGACAGCCTGCAGT
GGTTTCTGGTGTGCATAAGAAAATGAACATTAGCCTATGGAAGGCGGAATCAATTAGTCTTGATTTTGGAGACCACCAAGCTGATCTCCT
GAACTGCAAAGATAGCATCATTTCAAATGCCAATGTTAAGGAATTCTGGGATGGTTTTGAAGAAGTTTCAAAACGGCAGAAAAACAAGAG
TGGAGAAACAGTTGTTTTAAAATTGAAAGACTGGCCTTCAGGAGAAGACTTCAAGACTATGATGCCAGCAAGATACGAAGATCTTTTAAA
AAGTCTGCCATTGCCAGAATATTGTAATCCAGAAGGAAAATTCAATTTGGCCTCTCATTTGCCAGGATTTTTTGTACGTCCTGATCTAGG
ACCCAGGTTGTGCAGTGCCTATGGTGTAGTTGCTGCTAAAGATCATGATATAGGAACAACAAATCTCCATATTGAAGTTTCTGATGTTGT
AAATATACTAGTTTATGTTGGCATAGCAAAAGGAAATGGCATTCTCTCAAAAGCAGGAATTCTCAAGAAATTTGAGGAAGAAGATTTGGA
TGACATTTTAAGGAAAAGATTGAAGGACTCAAGTGAAATACCTGGTGCTCTGTGGCATATTTATGCTGGGAAAGATGTTGACAAGATAAG
GGAATTTCTTCAAAAGATTTCAAAAGAACAAGGCCTTGAAGTTCTACCAGAACATGATCCAATACGTGACCAAAGTTGGTATGTGAACAA
AAAGCTCCGTCAAAGGCTGCTTGAAGAATATGGAGTCAGAACCTGTACTCTTATTCAGTTCCTTGGTGATGCTATTGTTTTGCCAGCGGG
AGCACTTCATCAGGTTCAGAATTTTCACAGCTGTATTCAGGTAACTGAAGATTTTGTGTCTCCAGAACATCTTGTAGAGTCATTTCATTT
AACACAGGAACTGAGACTTTTGAAGGAAGAAATCAATTATGATGATAAACTACAGGTTAAAAATATTTTGTATCATGCAGTCAAAGAAAT
GGTGAGAGCCTTGAAGATACACGAGGATGAAGTAGAGGATATGGAAGAAAATTAAGTGTGATCCAGTTTGATATTTTTAGGTTGTTGAAC
TGGGATTACTTAACCTTGAATGATGATATGTATGCACACTGACTTTAAGCTTCATAAAACCATCAGTGCCAAGAAATTCTCTTTGTAGTA
ATTACTTGTTACTGACACCACAGCAGTATAGCATATGTCACAGCTCCTGTGATTCAATGTTATAAAACAAGCAGAATTTTAAAAGCAGCA
CTATATAGCTGTTTTGTATTATAGTGTATATGATGTTTGTGAAAATGCCAGATTTAAAATGATGTATTTATTTTTGGTAAAAAATAAAAA
ATTCTATGCTATATTGTTGATCAAGTGTAAATGTGACCTTGTACAGTTTACTAAAATTACTGATATTTTTCACTACATTGAGACAGTTAC
TGTGAGAATAGGACACAAACACCAGCTATTGCCTGCATCTGGGAAATTGCTGAATCGCACAGCAGTCATGTCATAATCAGAAAATTACTG
CCAAATAATTGTAAAATTTGTAAAGTATAAAGTATATAAAGTAGATACTAAATACAGACACTTCAATATTTTGTTGAAGCTATTGACTGT
ACAATTAAACATTTTCAAAAGGTGTAATTTATTTAAAATTGTCTCATTTTGGTAAAATTTATGTGAACTTTTAAAGCTAAATATTAAACT
TAATATGCTATGTAAATATATACATATATACATTTAATGATGTATTTTTTTAAAACATTGGCTTGCTTTTGTTAAAGTGCAAGTGTTACA

>1845_1845_4_ACTR3B-JMJD1C_ACTR3B_chr7_152522207_ENST00000537264_JMJD1C_chr10_65140242_ENST00000399262_length(amino acids)=2741AA_BP=257
MATQATLSPSSLFLHWPIRHGIIEDWDLMERFMEQVVFKYLRAEPEDHYFLMTEPPLNTPENREYLAEIMFESFNVPGLYIAVQAVLALA
ASWTSRQVGERTLTGIVIDSGDGVTHVIPVAEGYVIGSCIKHIPIAGRDITYFIQQLLREREVGIPPEQSLETAKAIKEKYCYICPDIVK
EFAKYDVDPRKWIKQYTGINAINQKKFVIDVGYERFLGPEIFFHPEFANPDFMESISDVVDEVIQNCPIDVRRPLYKVYVEFDDLEWDKR
EWVKVYEDFSTFLVEYHLIWAKRNDPSQTQGSKSKQIQWPALTFKPLVERNIPSSVTAVEFLVDKQLDFLTEDSAFQPYQDDIDSLNPVL
RDNPQLHEEVKVWVKEQKVQEIFMQGPYSLNGYRVRVYRQDSATQWFTGIITHHDLFTRTMIVMNDQVLEPQNVDPSMVQMTFLDDVVHS
LLKGENIGITSRRRSRANQNVNAVHSHYTRAQANSPRPAMNSQAAVPKQNTHQQQQQRSIRPNKRKGSDSSIPDEEKMKEEKYDYISRGE
NPKGKNKHLMNKRRKPEEDEKKLNMKRLRTDNVSDFSESSDSENSNKRIIDNSSEQKPENELKNKNTSKINGEEGKPHNNEKAGEETLKN
SQPPWDQIQEDKKHEEAEKRKSVDTQLQEDMIIHSSEQSTVSDHNSNDLLPQECNMDKTHTMELLPKEKFVSRPPTPKCVIDITNDTNLE
KVAQENSSTFGLQTLQKMDPNVSDSKHSIANAKFLETAKKDSDQSWVSDVVKVDLTQSSVTNASSGNDHLNMEKEKYVSYISPLSAVSVM
EDKLHKRSPPPETIKSKLNTSVDTHKIKSSPSPEVVKPKITHSPDSVKSKATYVNSQATGERRLANKIEHELSRCSFHPIPTRSSTLETT
KSPLIIDKNEHFTVYRDPALIGSETGANHISPFLSQHPFPLHSSSHRTCLNPGTHHPALTPAPHLLAGSSSQTPLPTINTHPLTSGPHHA
VHHPHLLPTVLPGVPTASLLGGHPRLESAHASSLSHLALAHQQQQQLLQHQSPHLLGQAHPSASYNQLGLYPIIWQYPNGTHAYSGLGLP
SSKWVHPENAVNAEASLRRNSPSPWLHQPTPVTSADGIGLLSHIPVRPSSAEPHRPLKITAHSSPPLTKTLVDHHKEELERKAFMEPLRS
VASTSAKNDLDLNRSQTGKDCHLHRHFVDPVLNQLQRPPQETGERLNKYKEEHRRILQESIDVAPFTTKIKGLEGERENYSRVASSSSSP
KSHIIKQDMDVERSVSDLYKMKHSVPQSLPQSNYFTTLSNSVVNEPPRSYPSKEVSNIYGDKQSNALAAAAANPQTLTSFITSLSKPPPL
IKHQPESEGLVGKIPEHLPHQIASHSVTTFRNDCRSPTHLTVSSTNTLRSMPALHRAPVFHPPIHHSLERKEGSYSSLSPPTLTPVMPVN
AGGKVQESQKPPTLIPEPKDSQANFKSSSEQSLTEMWRPNNNLSKEKTEWHVEKSSGKLQAAMASVIVRPSSSTKTDSMPAMQLASKDRV
SERSSAGAHKTDCLKLAEAGETGRIILPNVNSDSVHTKSEKNFQAVSQGSVPSSVMSAVNTMCNTKTDVITSAADTTSVSSWGGSEVISS
LSNTILASTSSECVSSKSVSQPVAQKQECKVSTTAPVTLASSKTGSVVQPSSGFSGTTDFIHLKKHKAALAAAQYKSSNASETEPNAIKN
QTLSASLPLDSTVICSTINKANSVGNGQASQTSQPNYHTKLKKAWLTRHSEEDKNTNKMENSGNSVSEIIKPCSVNLIASTSSDIQNSVD
SKIIVDKYVKDDKVNRRKAKRTYESGSESGDSDESESKSEQRTKRQPKPTYKKKQNDLQKRKGEIEEDLKPNGVLSRSAKERSKLKLQSN
SNTGIPRSVLKDWRKVKKLKQTGESFLQDDSCCEIGPNLQKCRECRLIRSKKGEEPAHSPVFCRFYYFRRLSFSKNGVVRIDGFSSPDQY
DDEAMSLWTHENFEDDELDIETSKYILDIIGDKFCQLVTSEKTALSWVKKDAKIAWKRAVRGVREMCDACEATLFNIHWVCQKCGFVVCL
DCYKAKERKSSRDKELYAWMKCVKGQPHDHKHLMPTQIIPGSVLTDLLDAMHTLREKYGIKSHCHCTNKQNLQVGNFPTMNGVSQVLQNV
LNHSNKISLCMPESQQQNTPPKSEKNGGSSPESDVGTDNKLTPPESQSPLHWLADLAEQKAREEKKENKELTLENQIKEEREQDNSESPN
GRTSPLVSQNNEQGSTLRDLLTTTAGKLRVGSTDAGIAFAPVYSMGAPSSKSGRTMPNILDDIIASVVENKIPPSKTSKINVKPELKEEP
EESIISAVDENNKLYSDIPHSWICEKHILWLKDYKNSSNWKLFKECWKQGQPAVVSGVHKKMNISLWKAESISLDFGDHQADLLNCKDSI
ISNANVKEFWDGFEEVSKRQKNKSGETVVLKLKDWPSGEDFKTMMPARYEDLLKSLPLPEYCNPEGKFNLASHLPGFFVRPDLGPRLCSA
YGVVAAKDHDIGTTNLHIEVSDVVNILVYVGIAKGNGILSKAGILKKFEEEDLDDILRKRLKDSSEIPGALWHIYAGKDVDKIREFLQKI
SKEQGLEVLPEHDPIRDQSWYVNKKLRQRLLEEYGVRTCTLIQFLGDAIVLPAGALHQVQNFHSCIQVTEDFVSPEHLVESFHLTQELRL

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Fusion Gene PPI Analysis for ACTR3B-JMJD1C


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ACTR3B-JMJD1C


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ACTR3B-JMJD1C


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneC0004352Autistic Disorder1CTD_human
TgeneC0010606Adenoid Cystic Carcinoma1CTD_human
TgeneC0012236DiGeorge Syndrome1ORPHANET
TgeneC0087031Juvenile-Onset Still Disease1CTD_human
TgeneC0220704Shprintzen syndrome1ORPHANET
TgeneC0431406Asymmetric crying face association1ORPHANET
TgeneC0795907CONOTRUNCAL ANOMALY FACE SYNDROME1ORPHANET
TgeneC1333813Central Nervous System Germinoma1ORPHANET
TgeneC293634622q11 Deletion Syndrome1ORPHANET
TgeneC326610122q11 partial monosomy syndrome1ORPHANET
TgeneC3495559Juvenile arthritis1CTD_human
TgeneC3714758Juvenile psoriatic arthritis1CTD_human
TgeneC4552091Polyarthritis, Juvenile, Rheumatoid Factor Negative1CTD_human
TgeneC4704862Polyarthritis, Juvenile, Rheumatoid Factor Positive1CTD_human