|
||||||
|
 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:BACH1-OSBPL8 (FusionGDB2 ID:HG571TG114882) |
Fusion Gene Summary for BACH1-OSBPL8 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: BACH1-OSBPL8 | Fusion gene ID: hg571tg114882 | Hgene | Tgene | Gene symbol | BACH1 | OSBPL8 | Gene ID | 571 | 114882 |
| Gene name | BTB domain and CNC homolog 1 | oxysterol binding protein like 8 | |
| Synonyms | BACH-1|BTBD24 | MST120|MSTP120|ORP8|OSBP10 | |
| Cytomap | ('BACH1')('OSBPL8') 21q21.3 | 12q21.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | transcription regulator protein BACH1BTB and CNC homology 1, basic leucine zipper transcription factor 1basic region leucine zipper transcriptional regulator BACH1 | oxysterol-binding protein-related protein 8OSBP-related protein 8 | |
| Modification date | 20200313 | 20200313 | |
| UniProtAcc | O14867 | . | |
| Ensembl transtripts involved in fusion gene | ENST00000286800, ENST00000399921, ENST00000462262, | ||
| Fusion gene scores | * DoF score | 7 X 4 X 7=196 | 13 X 9 X 3=351 |
| # samples | 7 | 13 | |
| ** MAII score | log2(7/196*10)=-1.48542682717024 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(13/351*10)=-1.43295940727611 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: BACH1 [Title/Abstract] AND OSBPL8 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | BACH1(30702014)-OSBPL8(76752591), # samples:2 | ||
| Anticipated loss of major functional domain due to fusion event. | BACH1-OSBPL8 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. BACH1-OSBPL8 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. BACH1-OSBPL8 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. BACH1-OSBPL8 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | BACH1 | GO:0000122 | negative regulation of transcription by RNA polymerase II | 24035498 |
| Hgene | BACH1 | GO:0061418 | regulation of transcription from RNA polymerase II promoter in response to hypoxia | 12511571 |
| Tgene | OSBPL8 | GO:0010891 | negative regulation of sequestering of triglyceride | 23028956 |
| Tgene | OSBPL8 | GO:0015914 | phospholipid transport | 26206935 |
| Tgene | OSBPL8 | GO:0045444 | fat cell differentiation | 23028956 |
| Fusion gene breakpoints across BACH1 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
 |
| Fusion gene breakpoints across OSBPL8 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
 |
| Fusion gene information * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | SARC | TCGA-3B-A9HS-01A | BACH1 | chr21 | 30702014 | - | OSBPL8 | chr12 | 76752591 | - |
| ChimerDB4 | SARC | TCGA-3B-A9HS-01A | BACH1 | chr21 | 30702014 | + | OSBPL8 | chr12 | 76752591 | - |
Top |
Fusion Gene ORF analysis for BACH1-OSBPL8 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-intron | ENST00000286800 | ENST00000552178 | BACH1 | chr21 | 30702014 | + | OSBPL8 | chr12 | 76752591 | - |
| 5CDS-intron | ENST00000399921 | ENST00000552178 | BACH1 | chr21 | 30702014 | + | OSBPL8 | chr12 | 76752591 | - |
| In-frame | ENST00000286800 | ENST00000261183 | BACH1 | chr21 | 30702014 | + | OSBPL8 | chr12 | 76752591 | - |
| In-frame | ENST00000286800 | ENST00000393249 | BACH1 | chr21 | 30702014 | + | OSBPL8 | chr12 | 76752591 | - |
| In-frame | ENST00000286800 | ENST00000393250 | BACH1 | chr21 | 30702014 | + | OSBPL8 | chr12 | 76752591 | - |
| In-frame | ENST00000399921 | ENST00000261183 | BACH1 | chr21 | 30702014 | + | OSBPL8 | chr12 | 76752591 | - |
| In-frame | ENST00000399921 | ENST00000393249 | BACH1 | chr21 | 30702014 | + | OSBPL8 | chr12 | 76752591 | - |
| In-frame | ENST00000399921 | ENST00000393250 | BACH1 | chr21 | 30702014 | + | OSBPL8 | chr12 | 76752591 | - |
| intron-3CDS | ENST00000462262 | ENST00000261183 | BACH1 | chr21 | 30702014 | + | OSBPL8 | chr12 | 76752591 | - |
| intron-3CDS | ENST00000462262 | ENST00000393249 | BACH1 | chr21 | 30702014 | + | OSBPL8 | chr12 | 76752591 | - |
| intron-3CDS | ENST00000462262 | ENST00000393250 | BACH1 | chr21 | 30702014 | + | OSBPL8 | chr12 | 76752591 | - |
| intron-intron | ENST00000462262 | ENST00000552178 | BACH1 | chr21 | 30702014 | + | OSBPL8 | chr12 | 76752591 | - |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000286800 | BACH1 | chr21 | 30702014 | + | ENST00000393249 | OSBPL8 | chr12 | 76752591 | - | 6353 | 1919 | 131 | 2260 | 709 |
| ENST00000286800 | BACH1 | chr21 | 30702014 | + | ENST00000261183 | OSBPL8 | chr12 | 76752591 | - | 6350 | 1919 | 131 | 2260 | 709 |
| ENST00000286800 | BACH1 | chr21 | 30702014 | + | ENST00000393250 | OSBPL8 | chr12 | 76752591 | - | 2314 | 1919 | 131 | 2260 | 709 |
| ENST00000399921 | BACH1 | chr21 | 30702014 | + | ENST00000393249 | OSBPL8 | chr12 | 76752591 | - | 6453 | 2019 | 231 | 2360 | 709 |
| ENST00000399921 | BACH1 | chr21 | 30702014 | + | ENST00000261183 | OSBPL8 | chr12 | 76752591 | - | 6450 | 2019 | 231 | 2360 | 709 |
| ENST00000399921 | BACH1 | chr21 | 30702014 | + | ENST00000393250 | OSBPL8 | chr12 | 76752591 | - | 2414 | 2019 | 231 | 2360 | 709 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000286800 | ENST00000393249 | BACH1 | chr21 | 30702014 | + | OSBPL8 | chr12 | 76752591 | - | 0.000129952 | 0.99987006 |
| ENST00000286800 | ENST00000261183 | BACH1 | chr21 | 30702014 | + | OSBPL8 | chr12 | 76752591 | - | 0.000129436 | 0.99987054 |
| ENST00000286800 | ENST00000393250 | BACH1 | chr21 | 30702014 | + | OSBPL8 | chr12 | 76752591 | - | 0.001397388 | 0.99860257 |
| ENST00000399921 | ENST00000393249 | BACH1 | chr21 | 30702014 | + | OSBPL8 | chr12 | 76752591 | - | 0.00013226 | 0.9998677 |
| ENST00000399921 | ENST00000261183 | BACH1 | chr21 | 30702014 | + | OSBPL8 | chr12 | 76752591 | - | 0.000131764 | 0.9998683 |
| ENST00000399921 | ENST00000393250 | BACH1 | chr21 | 30702014 | + | OSBPL8 | chr12 | 76752591 | - | 0.001228254 | 0.9987717 |
Top |
Fusion Genomic Features for BACH1-OSBPL8 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
 |
Top |
Fusion Protein Features for BACH1-OSBPL8 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr21:30702014/chr12:76752591) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| BACH1 | . |
| FUNCTION: Transcriptional regulator that acts as repressor or activator, depending on the context. Binds to NF-E2 DNA binding sites. Plays important roles in coordinating transcription activation and repression by MAFK (By similarity). Together with MAF, represses the transcription of genes under the control of the NFE2L2 oxidative stress pathway (PubMed:24035498). {ECO:0000250|UniProtKB:P97302, ECO:0000269|PubMed:24035498}. | FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | BACH1 | chr21:30702014 | chr12:76752591 | ENST00000286800 | + | 4 | 5 | 34_100 | 592 | 737.0 | Domain | BTB |
| Hgene | BACH1 | chr21:30702014 | chr12:76752591 | ENST00000399921 | + | 4 | 5 | 34_100 | 592 | 737.0 | Domain | BTB |
| Hgene | BACH1 | chr21:30702014 | chr12:76752591 | ENST00000286800 | + | 4 | 5 | 562_578 | 592 | 737.0 | Region | Basic motif |
| Hgene | BACH1 | chr21:30702014 | chr12:76752591 | ENST00000286800 | + | 4 | 5 | 582_589 | 592 | 737.0 | Region | Leucine-zipper |
| Hgene | BACH1 | chr21:30702014 | chr12:76752591 | ENST00000399921 | + | 4 | 5 | 562_578 | 592 | 737.0 | Region | Basic motif |
| Hgene | BACH1 | chr21:30702014 | chr12:76752591 | ENST00000399921 | + | 4 | 5 | 582_589 | 592 | 737.0 | Region | Leucine-zipper |
| Tgene | OSBPL8 | chr21:30702014 | chr12:76752591 | ENST00000261183 | 20 | 24 | 871_888 | 776 | 890.0 | Transmembrane | Helical | |
| Tgene | OSBPL8 | chr21:30702014 | chr12:76752591 | ENST00000393249 | 22 | 26 | 871_888 | 734 | 848.0 | Transmembrane | Helical | |
| Tgene | OSBPL8 | chr21:30702014 | chr12:76752591 | ENST00000393250 | 19 | 23 | 871_888 | 734 | 848.0 | Transmembrane | Helical |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | BACH1 | chr21:30702014 | chr12:76752591 | ENST00000286800 | + | 4 | 5 | 557_620 | 592 | 737.0 | Domain | bZIP |
| Hgene | BACH1 | chr21:30702014 | chr12:76752591 | ENST00000399921 | + | 4 | 5 | 557_620 | 592 | 737.0 | Domain | bZIP |
| Tgene | OSBPL8 | chr21:30702014 | chr12:76752591 | ENST00000261183 | 20 | 24 | 148_265 | 776 | 890.0 | Domain | PH | |
| Tgene | OSBPL8 | chr21:30702014 | chr12:76752591 | ENST00000393249 | 22 | 26 | 148_265 | 734 | 848.0 | Domain | PH | |
| Tgene | OSBPL8 | chr21:30702014 | chr12:76752591 | ENST00000393250 | 19 | 23 | 148_265 | 734 | 848.0 | Domain | PH | |
| Tgene | OSBPL8 | chr21:30702014 | chr12:76752591 | ENST00000261183 | 20 | 24 | 420_425 | 776 | 890.0 | Region | Phosphatidylserine binding | |
| Tgene | OSBPL8 | chr21:30702014 | chr12:76752591 | ENST00000261183 | 20 | 24 | 482_485 | 776 | 890.0 | Region | Phosphatidylinositol 4-phosphate binding | |
| Tgene | OSBPL8 | chr21:30702014 | chr12:76752591 | ENST00000393249 | 22 | 26 | 420_425 | 734 | 848.0 | Region | Phosphatidylserine binding | |
| Tgene | OSBPL8 | chr21:30702014 | chr12:76752591 | ENST00000393249 | 22 | 26 | 482_485 | 734 | 848.0 | Region | Phosphatidylinositol 4-phosphate binding | |
| Tgene | OSBPL8 | chr21:30702014 | chr12:76752591 | ENST00000393250 | 19 | 23 | 420_425 | 734 | 848.0 | Region | Phosphatidylserine binding | |
| Tgene | OSBPL8 | chr21:30702014 | chr12:76752591 | ENST00000393250 | 19 | 23 | 482_485 | 734 | 848.0 | Region | Phosphatidylinositol 4-phosphate binding |
Top |
Fusion Gene Sequence for BACH1-OSBPL8 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >8826_8826_1_BACH1-OSBPL8_BACH1_chr21_30702014_ENST00000286800_OSBPL8_chr12_76752591_ENST00000261183_length(transcript)=6350nt_BP=1919nt GAGTGAGTCACCTGACCGCTGCCCTCGCCGCCCGCCGGGCGCTCTCGCTTCAGTCAGTCGGGCCGCGCCGCGCCTCAGCTCTGGTTGATG ATAATTAGAAGCATGCTTTCCACTGAACTTCCCGACAACATTTGTTATGCAGAATGTCTCTGAGTGAGAACTCGGTTTTTGCCTATGAAT CTTCTGTGCATAGCACCAATGTTTTACTCAGCCTTAATGACCAGCGGAAGAAAGATGTGCTGTGCGATGTCACCATCTTTGTGGAGGGAC AGCGGTTCCGCGCTCACCGGTCCGTGCTGGCGGCATGCAGCAGTTACTTCCACTCAAGAATCGTAGGCCAGGCTGATGGAGAGCTGAACA TTACTCTTCCAGAAGAGGTGACAGTTAAAGGATTTGAACCTTTAATTCAGTTTGCCTACACTGCTAAACTGATTTTAAGTAAAGAGAATG TGGATGAAGTGTGCAAATGTGTGGAGTTTTTAAGTGTACATAATATTGAGGAATCCTGCTTTCAGTTTCTGAAATTTAAGTTTTTGGACT CCACTGCAGACCAGCAAGAATGCCCAAGAAAAAAATGCTTTTCATCACACTGTCAGAAAACAGACCTTAAACTTTCACTTTTGGACCAGA GGGATCTAGAAACTGATGAAGTGGAGGAATTTCTGGAAAATAAAAATGTTCAGACTCCTCAGTGTAAACTCCGCAGGTATCAAGGAAATG CAAAAGCCTCACCTCCTCTACAAGACAGTGCCAGTCAGACATATGAGTCCATGTGCTTAGAGAAGGATGCTGCTCTGGCCTTGCCTTCTT TATGCCCCAAATACAGAAAATTCCAAAAAGCATTTGGAACTGACAGAGTCCGTACTGGGGAATCTAGTGTCAAAGACATTCATGCTTCTG TTCAGCCAAATGAAAGGTCTGAAAATGAATGCCTGGGAGGAGTCCCGGAGTGTAGAGATTTGCAGGTGATGTTAAAATGTGACGAAAGTA AATTAGCAATGGAACCTGAAGAAACGAAGAAAGATCCTGCTTCTCAGTGCCCAACTGAAAAATCAGAAGTGACTCCTTTCCCCCACAATT CTTCCATAGACCCTCATGGACTTTATTCTTTGTCTCTTTTACACACATATGACCAATATGGTGACTTGAATTTTGCTGGTATGCAAAACA CAACAGTGTTAACAGAAAAGCCTTTGTCAGGTACAGACGTCCAAGAAAAAACATTTGGTGAAAGTCAGGATTTACCTTTGAAATCCGACT TGGGCACCAGGGAAGATAGTAGTGTTGCATCTAGTGATAGGAGTAGTGTGGAGCGAGAAGTGGCAGAACACCTAGCAAAAGGCTTCTGGA GTGACATTTGCAGCACGGACACTCCTTGCCAAATGCAGTTATCACCTGCTGTGGCCAAAGATGGCTCAGAACAGATCTCACAGAAACGGT CTGAGTGTCCGTGGTTAGGTATCAGGATTAGTGAGAGCCCAGAACCAGGTCAAAGGACTTTCACAACATTAAGTTCTGTCAACTGCCCTT TTATAAGTACTCTGAGTACTGAAGGCTGTTCAAGCAATTTGGAAATTGGAAACGATGATTATGTTTCAGAACCCCAGCAAGAACCTTGCC CATATGCTTGTGTCATTAGCTTGGGAGACGACTCTGAGACGGACACCGAAGGAGACAGTGAATCCTGTTCAGCCAGAGAACAAGAATGTG AGGTAAAACTGCCATTCAATGCACAACGGATAATTTCACTGTCTCGAAATGATTTTCAGTCCTTGTTGAAAATGCACAAGCTTACTCCAG AACAGCTGGATTGTATCCATGATATTCGAAGAAGAAGTAAAAACAGAATTGCTGCACAGCGCTGTCGCAAGAGAAAACTTGACTGTATAC AGAATCTTGAATCAGAAATTGAGAAGCTGGTTAGCGTCCCCAAAATGAAACATAAGCCAACCAGGCAACAGAAGAAAGTAGCAAAAGGCT ATTCCTCCCCAGAACCTGACATTCAAGACTCCTCTGGAAGTGAAGCTCAATCAGTAAAACCAAGTACAAGAAGAAAGAAAGGAATAGAAC TGGGAGACATTCAGAGTTCCATCGAATCTATAAAACAAACACAGGAAGAAATTAAAAGAAATATTATGGCTCTTCGAAATCATTTAGTTT CAAGCACACCGGCCACGGATTATTTTCTGCAACAAAAAGACTACTTCATCATTTTCCTCCTGATTTTGCTTCAAGTCATAATAAACTTCA TGTTCAAGTAGAAGTTCTCTACCATTGAATCAGTGAACTAGAAAGATCTGATTTGGCCTGGGACCAGTGTTCAAGTTGGTTTGGTCTTTA TTAAAAATCACAATATTCCGAAAACAAAAAAACCTAGGAGATAAATGTAGAGGTATTGACTTTTCGTATCTTTTATCTTCACACTGAAAC AAGAGCTATCCTATTTGATTATTAAAGTGAGCTATGTGTTAAGTGCCAGGACATTTCTAGCTTTTGTGAGAATGTGTCTACATATGAGTA TAATAAACCCACATGTATACACAATTGTCTCTTATGTACTCCTACCTGACAGTAGTCTTTGTATTCTATAGTATGTTCTGAGATATAATG TTAACATTGTTCATAACAAAAAATGCTATCAATCTTATAAATATATGTAATCTATTTTCTTCATAAAACAGGCACAAAAGTTTTATCAGT AAGGAATTACAGATTGAGAAATGATGGAATAATAGACATAATTAATTCAATACACTACTGTTAAAATCATTTGCAAAGCACTCAGCTCAA TTATCTTCTTAGAAAGAAAGAAAAAGTATGAATGGTCAAAATGAATACATCGAGAGAGATAAATGGCAAATTGCTTTTTTAAAAGTTTAC ATAAGTTTTTTTTAACCCCTAGAATTTAATATTTGTAGATGCAGGTAAATATATATACTTACGTGTATATCAGTATAAAAACACTGGTGT GCAATTAATTGGATTGATTATAATACCACCTTAAGCACTTGCTGAAAAAAGTGTGGTCAAAATTGATTGCTGTCCTTTTGTCTTATTTTT GTTTTTCTTAAGTCAGCTGGTTCATAACATAGGCCAAATTCTAGAGATGTTTATAGAGCATTTGAAGTGCTGATAATTTATGTTTTTTCA TTATGAAAACTTATTTTAGCTTTAGACTCCAGTGTGTTCAGTGAATAAGTAGAATATAAAAAAATATAACCAGTATTTTACTTCAAAAGC CAAAAAGAGGCAATAAGAAAAGACACTTTGTGGTGGCCTTTATGTGTGCATTAAAATTGGTTTCTGTAAAACGTGTAATAAGTTGAGTAT CTACGAAGAGTATCAAGTTCTGAAGTTTAATTTTTTTATTATCCTCCTCTCTTCTTAGTAACTTCTTTCTGTGGCAAAACCACAATTCTT TAAGATTCCTATTGTTCAGGCTAAGGCAAATTTTTTTGTTTGTTTCTTCAGTTTAATATTTTGATTTTGTGTTTTTACGTAAATATTTAT ATTCCTTGAAAGCAATTTTTGCCAAGGTAGTTCAGTTTAGGAATATGTTGTTCTAAAATATGTCTTAGAATCCTGAAAGCATAGATTTTG AAATGTTTTTTTAATGAAAATGAAGGTCAGAGAGAATAATTGCCCTGACCACATTTGCCTTTCAGTAGGAGGAGGCTGTGAAATAGTAAA ATTATAATCGTTTATGCCATGATAAATACAAGATTGGTAAATAAATACATTGATTGGTAAATTATGAGAATCAAAATGATAAAAAGAGCC TGCTTTTTTCCCTAACCAATATAGCTATCTTAAGTATCCTTAGGTTTCTGTGAAGAACCATTTCCCATGTTTTCTTGGCAAAATAATGCT GTATTCCATATGTACATGTGAAATGATGTTTTAAATTGATAAAAGCTTAAATAAGATCTACCTATACCCAGTATTTTCATGATATTAGAA CAAATGGGTTTTTGGTTATATTTTATATTTGTCAATATAATTTTTGTATTCACATTCTGTTACACTCTGCCTATTCATTGATATATGATA TTCTGTAAATATTGTACAATTTGATCTTTTTTATGGTTTAAATTAGTTAATTACATACAAATTGATTGGCTTATCACAAAAATCATTTCA TCAGTAAACCTTGTTAACATTTTGTACTGGTGACCCACCTCTTAGGACTTTGGTCTTATCCACGTGTATGTTGTTTTCATTTGGTCCAAA TAATATTTTATTTGTATGGGTATCTTCTAAGACTAAATAGGTAGTTGTGTTCTTTATTTTTAAAATTTCTTTTTAGAGCAAATGTTATGG GTTCTTACCCAAAGAGTCAAAAACTATTTCTTAAGAAAGAGCAGAGTTATTCATGACTGTTCTTTATACACTAAAAGCATGCATCTAATC TAATAGTCCTCTTATTATGCTTTTAGTTGTATGAGTCTCTTTCTATGAACTGAACACAAAACTCAGGAATTGGTGGCTTAATTTTAGATC AGTGCTTGTACTAGGCTTAGTTATATGAATCTTTATAACACATAATTACTAACTTTGTAGCCATATATGTAATTGACTTTGAATGTTATT TACCTGAAATTAATCTTCCTTCACACATGGACCGTAAACGGTTCCCAGTTGTCTGAGAGCCTCATGAGGGTTTCTAGGATTTATGACCTT ATGACCAGTTTTTTTCATTTACCAAGATTTTATTTTCCTACATGAAAATTTAATTGAGTAATAATTATTCACATGTGCATTTTCTTTTTA GCTGTTAAATGTACTATGCCATCATCCACCATTTAGTAAAATGTAGCTGGCCCAGGACATGTAAAAAAAAAAAAAAAACAACAACAATAA ATAGGGCATGTGAAATGTTAAGTTACAGCAATAGATATTTTATTTGTATTTCATGTTAGTACTTTTTTGTTTTATATCACTTATAAAGGT ACAGTGTACTCTTTGTCACAGCTCAGTTGGTAACCGCATTCCATTGAAAAGTTGGCCTTGTAAAATACAACTCTCATTTAATATTCATGC TTTTGTGCCTTTAAGAAAATATTTTTTGTCATTTTTTGTGTTACAGAACTATAATGTGATTCAAGGTGTTTATAGGCTTGTCATAAAAGG GTCATTTCTGTGTGTTACTTTCTTTTTATATAGCTATAGTATATTTAAACAATAATACTATCTTTTATAGGGGTTTGTCTATTTACCTAT TCTTTACTCAGACATTGATGTAGACTTGTCAGATTATTCTGAGTATTGTTAACAGTGCCTTTTCGATGGAATCACACTTTTTGGCTGTCA CCTTGTGCCATATACACACAAAATTTTGTGGAAGGCAGTTTTAACTTTCTGAAGAATATCTGTCAAAATTTAAGAAAACAAATGTATAAA ATTCCATTTTTTCCAGTGTTTAGCATTTCTAGTAAGCAGTGAGGTTGTTTGACATACAGTGATGATGGCATTATTGATAAGCCATACATG AGACTGCAGATTATATTGAATCATATTAAATGTACAGAAATAAAATATTAGATTTATATCAAATTTTCCAATTTGAACCAGTGGGGAAAA TCCCACAGAAATCAGTAAGTTTACATTTCAATTTCTATCTTATTTGACTAAGTGGAAAGAGATTCTTTAAAATGTATAACCTGCCATTAT GTAATTTGGTTTCATTTTATTCTACCTGTTGTGTGAGTTTAGTATATTTAATTTACTTTTTGTTACTCTTTACATACTGTTTATTTTTGT TAGTTTTTAATTGAAGATGGACTGTTGAAATTGTATAGGACCAGTGTCTTATTAATATGATTAATATATTTAGAAGAGCCACGTGAAACC CATGACAAAATGAATGTGAATATTCTTTCTAAAAATTTAGAAAATGTTATCTTTTTGCATTTATTATGTAAAACTGTTTTACAGTATCAA AATTTTTCACTTAAAGAAAAAAAATGCCATGAAACATTTGAACTGATGAGCCACAGAACTTCAGTTGAAATTTTTTTCACTTTTTAGCAT GCTAAATATACATCTGAGTTTAAATGTTCTGTTTAATGGCCATTCATAAATTCAAGCACTACCACTGGTCAGTTTTGTGTGATAGAATAA AAATATGTTACCTGCAGTGTAAGTACAGCACACTGTCAAATTCTTTTCCTTAAGGTGCACAGTAAATGTACAGATAGTTATAGGCCACTG TTTTGTAATGTAGTACATTTCTAATCTATTATTCCTAACCTATTATAACTGTTTGCAGAAAGAAAAGAATTTTTCTAATAATCTGTAAAA >8826_8826_1_BACH1-OSBPL8_BACH1_chr21_30702014_ENST00000286800_OSBPL8_chr12_76752591_ENST00000261183_length(amino acids)=709AA_BP=596 MLCRMSLSENSVFAYESSVHSTNVLLSLNDQRKKDVLCDVTIFVEGQRFRAHRSVLAACSSYFHSRIVGQADGELNITLPEEVTVKGFEP LIQFAYTAKLILSKENVDEVCKCVEFLSVHNIEESCFQFLKFKFLDSTADQQECPRKKCFSSHCQKTDLKLSLLDQRDLETDEVEEFLEN KNVQTPQCKLRRYQGNAKASPPLQDSASQTYESMCLEKDAALALPSLCPKYRKFQKAFGTDRVRTGESSVKDIHASVQPNERSENECLGG VPECRDLQVMLKCDESKLAMEPEETKKDPASQCPTEKSEVTPFPHNSSIDPHGLYSLSLLHTYDQYGDLNFAGMQNTTVLTEKPLSGTDV QEKTFGESQDLPLKSDLGTREDSSVASSDRSSVEREVAEHLAKGFWSDICSTDTPCQMQLSPAVAKDGSEQISQKRSECPWLGIRISESP EPGQRTFTTLSSVNCPFISTLSTEGCSSNLEIGNDDYVSEPQQEPCPYACVISLGDDSETDTEGDSESCSAREQECEVKLPFNAQRIISL SRNDFQSLLKMHKLTPEQLDCIHDIRRRSKNRIAAQRCRKRKLDCIQNLESEIEKLVSVPKMKHKPTRQQKKVAKGYSSPEPDIQDSSGS -------------------------------------------------------------- >8826_8826_2_BACH1-OSBPL8_BACH1_chr21_30702014_ENST00000286800_OSBPL8_chr12_76752591_ENST00000393249_length(transcript)=6353nt_BP=1919nt GAGTGAGTCACCTGACCGCTGCCCTCGCCGCCCGCCGGGCGCTCTCGCTTCAGTCAGTCGGGCCGCGCCGCGCCTCAGCTCTGGTTGATG ATAATTAGAAGCATGCTTTCCACTGAACTTCCCGACAACATTTGTTATGCAGAATGTCTCTGAGTGAGAACTCGGTTTTTGCCTATGAAT CTTCTGTGCATAGCACCAATGTTTTACTCAGCCTTAATGACCAGCGGAAGAAAGATGTGCTGTGCGATGTCACCATCTTTGTGGAGGGAC AGCGGTTCCGCGCTCACCGGTCCGTGCTGGCGGCATGCAGCAGTTACTTCCACTCAAGAATCGTAGGCCAGGCTGATGGAGAGCTGAACA TTACTCTTCCAGAAGAGGTGACAGTTAAAGGATTTGAACCTTTAATTCAGTTTGCCTACACTGCTAAACTGATTTTAAGTAAAGAGAATG TGGATGAAGTGTGCAAATGTGTGGAGTTTTTAAGTGTACATAATATTGAGGAATCCTGCTTTCAGTTTCTGAAATTTAAGTTTTTGGACT CCACTGCAGACCAGCAAGAATGCCCAAGAAAAAAATGCTTTTCATCACACTGTCAGAAAACAGACCTTAAACTTTCACTTTTGGACCAGA GGGATCTAGAAACTGATGAAGTGGAGGAATTTCTGGAAAATAAAAATGTTCAGACTCCTCAGTGTAAACTCCGCAGGTATCAAGGAAATG CAAAAGCCTCACCTCCTCTACAAGACAGTGCCAGTCAGACATATGAGTCCATGTGCTTAGAGAAGGATGCTGCTCTGGCCTTGCCTTCTT TATGCCCCAAATACAGAAAATTCCAAAAAGCATTTGGAACTGACAGAGTCCGTACTGGGGAATCTAGTGTCAAAGACATTCATGCTTCTG TTCAGCCAAATGAAAGGTCTGAAAATGAATGCCTGGGAGGAGTCCCGGAGTGTAGAGATTTGCAGGTGATGTTAAAATGTGACGAAAGTA AATTAGCAATGGAACCTGAAGAAACGAAGAAAGATCCTGCTTCTCAGTGCCCAACTGAAAAATCAGAAGTGACTCCTTTCCCCCACAATT CTTCCATAGACCCTCATGGACTTTATTCTTTGTCTCTTTTACACACATATGACCAATATGGTGACTTGAATTTTGCTGGTATGCAAAACA CAACAGTGTTAACAGAAAAGCCTTTGTCAGGTACAGACGTCCAAGAAAAAACATTTGGTGAAAGTCAGGATTTACCTTTGAAATCCGACT TGGGCACCAGGGAAGATAGTAGTGTTGCATCTAGTGATAGGAGTAGTGTGGAGCGAGAAGTGGCAGAACACCTAGCAAAAGGCTTCTGGA GTGACATTTGCAGCACGGACACTCCTTGCCAAATGCAGTTATCACCTGCTGTGGCCAAAGATGGCTCAGAACAGATCTCACAGAAACGGT CTGAGTGTCCGTGGTTAGGTATCAGGATTAGTGAGAGCCCAGAACCAGGTCAAAGGACTTTCACAACATTAAGTTCTGTCAACTGCCCTT TTATAAGTACTCTGAGTACTGAAGGCTGTTCAAGCAATTTGGAAATTGGAAACGATGATTATGTTTCAGAACCCCAGCAAGAACCTTGCC CATATGCTTGTGTCATTAGCTTGGGAGACGACTCTGAGACGGACACCGAAGGAGACAGTGAATCCTGTTCAGCCAGAGAACAAGAATGTG AGGTAAAACTGCCATTCAATGCACAACGGATAATTTCACTGTCTCGAAATGATTTTCAGTCCTTGTTGAAAATGCACAAGCTTACTCCAG AACAGCTGGATTGTATCCATGATATTCGAAGAAGAAGTAAAAACAGAATTGCTGCACAGCGCTGTCGCAAGAGAAAACTTGACTGTATAC AGAATCTTGAATCAGAAATTGAGAAGCTGGTTAGCGTCCCCAAAATGAAACATAAGCCAACCAGGCAACAGAAGAAAGTAGCAAAAGGCT ATTCCTCCCCAGAACCTGACATTCAAGACTCCTCTGGAAGTGAAGCTCAATCAGTAAAACCAAGTACAAGAAGAAAGAAAGGAATAGAAC TGGGAGACATTCAGAGTTCCATCGAATCTATAAAACAAACACAGGAAGAAATTAAAAGAAATATTATGGCTCTTCGAAATCATTTAGTTT CAAGCACACCGGCCACGGATTATTTTCTGCAACAAAAAGACTACTTCATCATTTTCCTCCTGATTTTGCTTCAAGTCATAATAAACTTCA TGTTCAAGTAGAAGTTCTCTACCATTGAATCAGTGAACTAGAAAGATCTGATTTGGCCTGGGACCAGTGTTCAAGTTGGTTTGGTCTTTA TTAAAAATCACAATATTCCGAAAACAAAAAAACCTAGGAGATAAATGTAGAGGTATTGACTTTTCGTATCTTTTATCTTCACACTGAAAC AAGAGCTATCCTATTTGATTATTAAAGTGAGCTATGTGTTAAGTGCCAGGACATTTCTAGCTTTTGTGAGAATGTGTCTACATATGAGTA TAATAAACCCACATGTATACACAATTGTCTCTTATGTACTCCTACCTGACAGTAGTCTTTGTATTCTATAGTATGTTCTGAGATATAATG TTAACATTGTTCATAACAAAAAATGCTATCAATCTTATAAATATATGTAATCTATTTTCTTCATAAAACAGGCACAAAAGTTTTATCAGT AAGGAATTACAGATTGAGAAATGATGGAATAATAGACATAATTAATTCAATACACTACTGTTAAAATCATTTGCAAAGCACTCAGCTCAA TTATCTTCTTAGAAAGAAAGAAAAAGTATGAATGGTCAAAATGAATACATCGAGAGAGATAAATGGCAAATTGCTTTTTTAAAAGTTTAC ATAAGTTTTTTTTAACCCCTAGAATTTAATATTTGTAGATGCAGGTAAATATATATACTTACGTGTATATCAGTATAAAAACACTGGTGT GCAATTAATTGGATTGATTATAATACCACCTTAAGCACTTGCTGAAAAAAGTGTGGTCAAAATTGATTGCTGTCCTTTTGTCTTATTTTT GTTTTTCTTAAGTCAGCTGGTTCATAACATAGGCCAAATTCTAGAGATGTTTATAGAGCATTTGAAGTGCTGATAATTTATGTTTTTTCA TTATGAAAACTTATTTTAGCTTTAGACTCCAGTGTGTTCAGTGAATAAGTAGAATATAAAAAAATATAACCAGTATTTTACTTCAAAAGC CAAAAAGAGGCAATAAGAAAAGACACTTTGTGGTGGCCTTTATGTGTGCATTAAAATTGGTTTCTGTAAAACGTGTAATAAGTTGAGTAT CTACGAAGAGTATCAAGTTCTGAAGTTTAATTTTTTTATTATCCTCCTCTCTTCTTAGTAACTTCTTTCTGTGGCAAAACCACAATTCTT TAAGATTCCTATTGTTCAGGCTAAGGCAAATTTTTTTGTTTGTTTCTTCAGTTTAATATTTTGATTTTGTGTTTTTACGTAAATATTTAT ATTCCTTGAAAGCAATTTTTGCCAAGGTAGTTCAGTTTAGGAATATGTTGTTCTAAAATATGTCTTAGAATCCTGAAAGCATAGATTTTG AAATGTTTTTTTAATGAAAATGAAGGTCAGAGAGAATAATTGCCCTGACCACATTTGCCTTTCAGTAGGAGGAGGCTGTGAAATAGTAAA ATTATAATCGTTTATGCCATGATAAATACAAGATTGGTAAATAAATACATTGATTGGTAAATTATGAGAATCAAAATGATAAAAAGAGCC TGCTTTTTTCCCTAACCAATATAGCTATCTTAAGTATCCTTAGGTTTCTGTGAAGAACCATTTCCCATGTTTTCTTGGCAAAATAATGCT GTATTCCATATGTACATGTGAAATGATGTTTTAAATTGATAAAAGCTTAAATAAGATCTACCTATACCCAGTATTTTCATGATATTAGAA CAAATGGGTTTTTGGTTATATTTTATATTTGTCAATATAATTTTTGTATTCACATTCTGTTACACTCTGCCTATTCATTGATATATGATA TTCTGTAAATATTGTACAATTTGATCTTTTTTATGGTTTAAATTAGTTAATTACATACAAATTGATTGGCTTATCACAAAAATCATTTCA TCAGTAAACCTTGTTAACATTTTGTACTGGTGACCCACCTCTTAGGACTTTGGTCTTATCCACGTGTATGTTGTTTTCATTTGGTCCAAA TAATATTTTATTTGTATGGGTATCTTCTAAGACTAAATAGGTAGTTGTGTTCTTTATTTTTAAAATTTCTTTTTAGAGCAAATGTTATGG GTTCTTACCCAAAGAGTCAAAAACTATTTCTTAAGAAAGAGCAGAGTTATTCATGACTGTTCTTTATACACTAAAAGCATGCATCTAATC TAATAGTCCTCTTATTATGCTTTTAGTTGTATGAGTCTCTTTCTATGAACTGAACACAAAACTCAGGAATTGGTGGCTTAATTTTAGATC AGTGCTTGTACTAGGCTTAGTTATATGAATCTTTATAACACATAATTACTAACTTTGTAGCCATATATGTAATTGACTTTGAATGTTATT TACCTGAAATTAATCTTCCTTCACACATGGACCGTAAACGGTTCCCAGTTGTCTGAGAGCCTCATGAGGGTTTCTAGGATTTATGACCTT ATGACCAGTTTTTTTCATTTACCAAGATTTTATTTTCCTACATGAAAATTTAATTGAGTAATAATTATTCACATGTGCATTTTCTTTTTA GCTGTTAAATGTACTATGCCATCATCCACCATTTAGTAAAATGTAGCTGGCCCAGGACATGTAAAAAAAAAAAAAAAACAACAACAATAA ATAGGGCATGTGAAATGTTAAGTTACAGCAATAGATATTTTATTTGTATTTCATGTTAGTACTTTTTTGTTTTATATCACTTATAAAGGT ACAGTGTACTCTTTGTCACAGCTCAGTTGGTAACCGCATTCCATTGAAAAGTTGGCCTTGTAAAATACAACTCTCATTTAATATTCATGC TTTTGTGCCTTTAAGAAAATATTTTTTGTCATTTTTTGTGTTACAGAACTATAATGTGATTCAAGGTGTTTATAGGCTTGTCATAAAAGG GTCATTTCTGTGTGTTACTTTCTTTTTATATAGCTATAGTATATTTAAACAATAATACTATCTTTTATAGGGGTTTGTCTATTTACCTAT TCTTTACTCAGACATTGATGTAGACTTGTCAGATTATTCTGAGTATTGTTAACAGTGCCTTTTCGATGGAATCACACTTTTTGGCTGTCA CCTTGTGCCATATACACACAAAATTTTGTGGAAGGCAGTTTTAACTTTCTGAAGAATATCTGTCAAAATTTAAGAAAACAAATGTATAAA ATTCCATTTTTTCCAGTGTTTAGCATTTCTAGTAAGCAGTGAGGTTGTTTGACATACAGTGATGATGGCATTATTGATAAGCCATACATG AGACTGCAGATTATATTGAATCATATTAAATGTACAGAAATAAAATATTAGATTTATATCAAATTTTCCAATTTGAACCAGTGGGGAAAA TCCCACAGAAATCAGTAAGTTTACATTTCAATTTCTATCTTATTTGACTAAGTGGAAAGAGATTCTTTAAAATGTATAACCTGCCATTAT GTAATTTGGTTTCATTTTATTCTACCTGTTGTGTGAGTTTAGTATATTTAATTTACTTTTTGTTACTCTTTACATACTGTTTATTTTTGT TAGTTTTTAATTGAAGATGGACTGTTGAAATTGTATAGGACCAGTGTCTTATTAATATGATTAATATATTTAGAAGAGCCACGTGAAACC CATGACAAAATGAATGTGAATATTCTTTCTAAAAATTTAGAAAATGTTATCTTTTTGCATTTATTATGTAAAACTGTTTTACAGTATCAA AATTTTTCACTTAAAGAAAAAAAATGCCATGAAACATTTGAACTGATGAGCCACAGAACTTCAGTTGAAATTTTTTTCACTTTTTAGCAT GCTAAATATACATCTGAGTTTAAATGTTCTGTTTAATGGCCATTCATAAATTCAAGCACTACCACTGGTCAGTTTTGTGTGATAGAATAA AAATATGTTACCTGCAGTGTAAGTACAGCACACTGTCAAATTCTTTTCCTTAAGGTGCACAGTAAATGTACAGATAGTTATAGGCCACTG TTTTGTAATGTAGTACATTTCTAATCTATTATTCCTAACCTATTATAACTGTTTGCAGAAAGAAAAGAATTTTTCTAATAATCTGTAAAA >8826_8826_2_BACH1-OSBPL8_BACH1_chr21_30702014_ENST00000286800_OSBPL8_chr12_76752591_ENST00000393249_length(amino acids)=709AA_BP=596 MLCRMSLSENSVFAYESSVHSTNVLLSLNDQRKKDVLCDVTIFVEGQRFRAHRSVLAACSSYFHSRIVGQADGELNITLPEEVTVKGFEP LIQFAYTAKLILSKENVDEVCKCVEFLSVHNIEESCFQFLKFKFLDSTADQQECPRKKCFSSHCQKTDLKLSLLDQRDLETDEVEEFLEN KNVQTPQCKLRRYQGNAKASPPLQDSASQTYESMCLEKDAALALPSLCPKYRKFQKAFGTDRVRTGESSVKDIHASVQPNERSENECLGG VPECRDLQVMLKCDESKLAMEPEETKKDPASQCPTEKSEVTPFPHNSSIDPHGLYSLSLLHTYDQYGDLNFAGMQNTTVLTEKPLSGTDV QEKTFGESQDLPLKSDLGTREDSSVASSDRSSVEREVAEHLAKGFWSDICSTDTPCQMQLSPAVAKDGSEQISQKRSECPWLGIRISESP EPGQRTFTTLSSVNCPFISTLSTEGCSSNLEIGNDDYVSEPQQEPCPYACVISLGDDSETDTEGDSESCSAREQECEVKLPFNAQRIISL SRNDFQSLLKMHKLTPEQLDCIHDIRRRSKNRIAAQRCRKRKLDCIQNLESEIEKLVSVPKMKHKPTRQQKKVAKGYSSPEPDIQDSSGS -------------------------------------------------------------- >8826_8826_3_BACH1-OSBPL8_BACH1_chr21_30702014_ENST00000286800_OSBPL8_chr12_76752591_ENST00000393250_length(transcript)=2314nt_BP=1919nt GAGTGAGTCACCTGACCGCTGCCCTCGCCGCCCGCCGGGCGCTCTCGCTTCAGTCAGTCGGGCCGCGCCGCGCCTCAGCTCTGGTTGATG ATAATTAGAAGCATGCTTTCCACTGAACTTCCCGACAACATTTGTTATGCAGAATGTCTCTGAGTGAGAACTCGGTTTTTGCCTATGAAT CTTCTGTGCATAGCACCAATGTTTTACTCAGCCTTAATGACCAGCGGAAGAAAGATGTGCTGTGCGATGTCACCATCTTTGTGGAGGGAC AGCGGTTCCGCGCTCACCGGTCCGTGCTGGCGGCATGCAGCAGTTACTTCCACTCAAGAATCGTAGGCCAGGCTGATGGAGAGCTGAACA TTACTCTTCCAGAAGAGGTGACAGTTAAAGGATTTGAACCTTTAATTCAGTTTGCCTACACTGCTAAACTGATTTTAAGTAAAGAGAATG TGGATGAAGTGTGCAAATGTGTGGAGTTTTTAAGTGTACATAATATTGAGGAATCCTGCTTTCAGTTTCTGAAATTTAAGTTTTTGGACT CCACTGCAGACCAGCAAGAATGCCCAAGAAAAAAATGCTTTTCATCACACTGTCAGAAAACAGACCTTAAACTTTCACTTTTGGACCAGA GGGATCTAGAAACTGATGAAGTGGAGGAATTTCTGGAAAATAAAAATGTTCAGACTCCTCAGTGTAAACTCCGCAGGTATCAAGGAAATG CAAAAGCCTCACCTCCTCTACAAGACAGTGCCAGTCAGACATATGAGTCCATGTGCTTAGAGAAGGATGCTGCTCTGGCCTTGCCTTCTT TATGCCCCAAATACAGAAAATTCCAAAAAGCATTTGGAACTGACAGAGTCCGTACTGGGGAATCTAGTGTCAAAGACATTCATGCTTCTG TTCAGCCAAATGAAAGGTCTGAAAATGAATGCCTGGGAGGAGTCCCGGAGTGTAGAGATTTGCAGGTGATGTTAAAATGTGACGAAAGTA AATTAGCAATGGAACCTGAAGAAACGAAGAAAGATCCTGCTTCTCAGTGCCCAACTGAAAAATCAGAAGTGACTCCTTTCCCCCACAATT CTTCCATAGACCCTCATGGACTTTATTCTTTGTCTCTTTTACACACATATGACCAATATGGTGACTTGAATTTTGCTGGTATGCAAAACA CAACAGTGTTAACAGAAAAGCCTTTGTCAGGTACAGACGTCCAAGAAAAAACATTTGGTGAAAGTCAGGATTTACCTTTGAAATCCGACT TGGGCACCAGGGAAGATAGTAGTGTTGCATCTAGTGATAGGAGTAGTGTGGAGCGAGAAGTGGCAGAACACCTAGCAAAAGGCTTCTGGA GTGACATTTGCAGCACGGACACTCCTTGCCAAATGCAGTTATCACCTGCTGTGGCCAAAGATGGCTCAGAACAGATCTCACAGAAACGGT CTGAGTGTCCGTGGTTAGGTATCAGGATTAGTGAGAGCCCAGAACCAGGTCAAAGGACTTTCACAACATTAAGTTCTGTCAACTGCCCTT TTATAAGTACTCTGAGTACTGAAGGCTGTTCAAGCAATTTGGAAATTGGAAACGATGATTATGTTTCAGAACCCCAGCAAGAACCTTGCC CATATGCTTGTGTCATTAGCTTGGGAGACGACTCTGAGACGGACACCGAAGGAGACAGTGAATCCTGTTCAGCCAGAGAACAAGAATGTG AGGTAAAACTGCCATTCAATGCACAACGGATAATTTCACTGTCTCGAAATGATTTTCAGTCCTTGTTGAAAATGCACAAGCTTACTCCAG AACAGCTGGATTGTATCCATGATATTCGAAGAAGAAGTAAAAACAGAATTGCTGCACAGCGCTGTCGCAAGAGAAAACTTGACTGTATAC AGAATCTTGAATCAGAAATTGAGAAGCTGGTTAGCGTCCCCAAAATGAAACATAAGCCAACCAGGCAACAGAAGAAAGTAGCAAAAGGCT ATTCCTCCCCAGAACCTGACATTCAAGACTCCTCTGGAAGTGAAGCTCAATCAGTAAAACCAAGTACAAGAAGAAAGAAAGGAATAGAAC TGGGAGACATTCAGAGTTCCATCGAATCTATAAAACAAACACAGGAAGAAATTAAAAGAAATATTATGGCTCTTCGAAATCATTTAGTTT CAAGCACACCGGCCACGGATTATTTTCTGCAACAAAAAGACTACTTCATCATTTTCCTCCTGATTTTGCTTCAAGTCATAATAAACTTCA >8826_8826_3_BACH1-OSBPL8_BACH1_chr21_30702014_ENST00000286800_OSBPL8_chr12_76752591_ENST00000393250_length(amino acids)=709AA_BP=596 MLCRMSLSENSVFAYESSVHSTNVLLSLNDQRKKDVLCDVTIFVEGQRFRAHRSVLAACSSYFHSRIVGQADGELNITLPEEVTVKGFEP LIQFAYTAKLILSKENVDEVCKCVEFLSVHNIEESCFQFLKFKFLDSTADQQECPRKKCFSSHCQKTDLKLSLLDQRDLETDEVEEFLEN KNVQTPQCKLRRYQGNAKASPPLQDSASQTYESMCLEKDAALALPSLCPKYRKFQKAFGTDRVRTGESSVKDIHASVQPNERSENECLGG VPECRDLQVMLKCDESKLAMEPEETKKDPASQCPTEKSEVTPFPHNSSIDPHGLYSLSLLHTYDQYGDLNFAGMQNTTVLTEKPLSGTDV QEKTFGESQDLPLKSDLGTREDSSVASSDRSSVEREVAEHLAKGFWSDICSTDTPCQMQLSPAVAKDGSEQISQKRSECPWLGIRISESP EPGQRTFTTLSSVNCPFISTLSTEGCSSNLEIGNDDYVSEPQQEPCPYACVISLGDDSETDTEGDSESCSAREQECEVKLPFNAQRIISL SRNDFQSLLKMHKLTPEQLDCIHDIRRRSKNRIAAQRCRKRKLDCIQNLESEIEKLVSVPKMKHKPTRQQKKVAKGYSSPEPDIQDSSGS -------------------------------------------------------------- >8826_8826_4_BACH1-OSBPL8_BACH1_chr21_30702014_ENST00000399921_OSBPL8_chr12_76752591_ENST00000261183_length(transcript)=6450nt_BP=2019nt GTCTACTCAGCCCGGTGGCTGTCGCGCGTGGAATCGCGTAAGAAAAGCCGAGTTTGTGGCTGGGGAGAGAAGGCCACCGTGCTGAGCTGG ATTTAGCGAAGACTGGTTTTGGGGACCGGAGAGCCCAGGACTCCCTTTGTTGGAGTTTTGCCCACGCGTTGTAATTAAGCCTCGCACAAT ATGGTTGATGATAATTAGAAGCATGCTTTCCACTGAACTTCCCGACAACATTTGTTATGCAGAATGTCTCTGAGTGAGAACTCGGTTTTT GCCTATGAATCTTCTGTGCATAGCACCAATGTTTTACTCAGCCTTAATGACCAGCGGAAGAAAGATGTGCTGTGCGATGTCACCATCTTT GTGGAGGGACAGCGGTTCCGCGCTCACCGGTCCGTGCTGGCGGCATGCAGCAGTTACTTCCACTCAAGAATCGTAGGCCAGGCTGATGGA GAGCTGAACATTACTCTTCCAGAAGAGGTGACAGTTAAAGGATTTGAACCTTTAATTCAGTTTGCCTACACTGCTAAACTGATTTTAAGT AAAGAGAATGTGGATGAAGTGTGCAAATGTGTGGAGTTTTTAAGTGTACATAATATTGAGGAATCCTGCTTTCAGTTTCTGAAATTTAAG TTTTTGGACTCCACTGCAGACCAGCAAGAATGCCCAAGAAAAAAATGCTTTTCATCACACTGTCAGAAAACAGACCTTAAACTTTCACTT TTGGACCAGAGGGATCTAGAAACTGATGAAGTGGAGGAATTTCTGGAAAATAAAAATGTTCAGACTCCTCAGTGTAAACTCCGCAGGTAT CAAGGAAATGCAAAAGCCTCACCTCCTCTACAAGACAGTGCCAGTCAGACATATGAGTCCATGTGCTTAGAGAAGGATGCTGCTCTGGCC TTGCCTTCTTTATGCCCCAAATACAGAAAATTCCAAAAAGCATTTGGAACTGACAGAGTCCGTACTGGGGAATCTAGTGTCAAAGACATT CATGCTTCTGTTCAGCCAAATGAAAGGTCTGAAAATGAATGCCTGGGAGGAGTCCCGGAGTGTAGAGATTTGCAGGTGATGTTAAAATGT GACGAAAGTAAATTAGCAATGGAACCTGAAGAAACGAAGAAAGATCCTGCTTCTCAGTGCCCAACTGAAAAATCAGAAGTGACTCCTTTC CCCCACAATTCTTCCATAGACCCTCATGGACTTTATTCTTTGTCTCTTTTACACACATATGACCAATATGGTGACTTGAATTTTGCTGGT ATGCAAAACACAACAGTGTTAACAGAAAAGCCTTTGTCAGGTACAGACGTCCAAGAAAAAACATTTGGTGAAAGTCAGGATTTACCTTTG AAATCCGACTTGGGCACCAGGGAAGATAGTAGTGTTGCATCTAGTGATAGGAGTAGTGTGGAGCGAGAAGTGGCAGAACACCTAGCAAAA GGCTTCTGGAGTGACATTTGCAGCACGGACACTCCTTGCCAAATGCAGTTATCACCTGCTGTGGCCAAAGATGGCTCAGAACAGATCTCA CAGAAACGGTCTGAGTGTCCGTGGTTAGGTATCAGGATTAGTGAGAGCCCAGAACCAGGTCAAAGGACTTTCACAACATTAAGTTCTGTC AACTGCCCTTTTATAAGTACTCTGAGTACTGAAGGCTGTTCAAGCAATTTGGAAATTGGAAACGATGATTATGTTTCAGAACCCCAGCAA GAACCTTGCCCATATGCTTGTGTCATTAGCTTGGGAGACGACTCTGAGACGGACACCGAAGGAGACAGTGAATCCTGTTCAGCCAGAGAA CAAGAATGTGAGGTAAAACTGCCATTCAATGCACAACGGATAATTTCACTGTCTCGAAATGATTTTCAGTCCTTGTTGAAAATGCACAAG CTTACTCCAGAACAGCTGGATTGTATCCATGATATTCGAAGAAGAAGTAAAAACAGAATTGCTGCACAGCGCTGTCGCAAGAGAAAACTT GACTGTATACAGAATCTTGAATCAGAAATTGAGAAGCTGGTTAGCGTCCCCAAAATGAAACATAAGCCAACCAGGCAACAGAAGAAAGTA GCAAAAGGCTATTCCTCCCCAGAACCTGACATTCAAGACTCCTCTGGAAGTGAAGCTCAATCAGTAAAACCAAGTACAAGAAGAAAGAAA GGAATAGAACTGGGAGACATTCAGAGTTCCATCGAATCTATAAAACAAACACAGGAAGAAATTAAAAGAAATATTATGGCTCTTCGAAAT CATTTAGTTTCAAGCACACCGGCCACGGATTATTTTCTGCAACAAAAAGACTACTTCATCATTTTCCTCCTGATTTTGCTTCAAGTCATA ATAAACTTCATGTTCAAGTAGAAGTTCTCTACCATTGAATCAGTGAACTAGAAAGATCTGATTTGGCCTGGGACCAGTGTTCAAGTTGGT TTGGTCTTTATTAAAAATCACAATATTCCGAAAACAAAAAAACCTAGGAGATAAATGTAGAGGTATTGACTTTTCGTATCTTTTATCTTC ACACTGAAACAAGAGCTATCCTATTTGATTATTAAAGTGAGCTATGTGTTAAGTGCCAGGACATTTCTAGCTTTTGTGAGAATGTGTCTA CATATGAGTATAATAAACCCACATGTATACACAATTGTCTCTTATGTACTCCTACCTGACAGTAGTCTTTGTATTCTATAGTATGTTCTG AGATATAATGTTAACATTGTTCATAACAAAAAATGCTATCAATCTTATAAATATATGTAATCTATTTTCTTCATAAAACAGGCACAAAAG TTTTATCAGTAAGGAATTACAGATTGAGAAATGATGGAATAATAGACATAATTAATTCAATACACTACTGTTAAAATCATTTGCAAAGCA CTCAGCTCAATTATCTTCTTAGAAAGAAAGAAAAAGTATGAATGGTCAAAATGAATACATCGAGAGAGATAAATGGCAAATTGCTTTTTT AAAAGTTTACATAAGTTTTTTTTAACCCCTAGAATTTAATATTTGTAGATGCAGGTAAATATATATACTTACGTGTATATCAGTATAAAA ACACTGGTGTGCAATTAATTGGATTGATTATAATACCACCTTAAGCACTTGCTGAAAAAAGTGTGGTCAAAATTGATTGCTGTCCTTTTG TCTTATTTTTGTTTTTCTTAAGTCAGCTGGTTCATAACATAGGCCAAATTCTAGAGATGTTTATAGAGCATTTGAAGTGCTGATAATTTA TGTTTTTTCATTATGAAAACTTATTTTAGCTTTAGACTCCAGTGTGTTCAGTGAATAAGTAGAATATAAAAAAATATAACCAGTATTTTA CTTCAAAAGCCAAAAAGAGGCAATAAGAAAAGACACTTTGTGGTGGCCTTTATGTGTGCATTAAAATTGGTTTCTGTAAAACGTGTAATA AGTTGAGTATCTACGAAGAGTATCAAGTTCTGAAGTTTAATTTTTTTATTATCCTCCTCTCTTCTTAGTAACTTCTTTCTGTGGCAAAAC CACAATTCTTTAAGATTCCTATTGTTCAGGCTAAGGCAAATTTTTTTGTTTGTTTCTTCAGTTTAATATTTTGATTTTGTGTTTTTACGT AAATATTTATATTCCTTGAAAGCAATTTTTGCCAAGGTAGTTCAGTTTAGGAATATGTTGTTCTAAAATATGTCTTAGAATCCTGAAAGC ATAGATTTTGAAATGTTTTTTTAATGAAAATGAAGGTCAGAGAGAATAATTGCCCTGACCACATTTGCCTTTCAGTAGGAGGAGGCTGTG AAATAGTAAAATTATAATCGTTTATGCCATGATAAATACAAGATTGGTAAATAAATACATTGATTGGTAAATTATGAGAATCAAAATGAT AAAAAGAGCCTGCTTTTTTCCCTAACCAATATAGCTATCTTAAGTATCCTTAGGTTTCTGTGAAGAACCATTTCCCATGTTTTCTTGGCA AAATAATGCTGTATTCCATATGTACATGTGAAATGATGTTTTAAATTGATAAAAGCTTAAATAAGATCTACCTATACCCAGTATTTTCAT GATATTAGAACAAATGGGTTTTTGGTTATATTTTATATTTGTCAATATAATTTTTGTATTCACATTCTGTTACACTCTGCCTATTCATTG ATATATGATATTCTGTAAATATTGTACAATTTGATCTTTTTTATGGTTTAAATTAGTTAATTACATACAAATTGATTGGCTTATCACAAA AATCATTTCATCAGTAAACCTTGTTAACATTTTGTACTGGTGACCCACCTCTTAGGACTTTGGTCTTATCCACGTGTATGTTGTTTTCAT TTGGTCCAAATAATATTTTATTTGTATGGGTATCTTCTAAGACTAAATAGGTAGTTGTGTTCTTTATTTTTAAAATTTCTTTTTAGAGCA AATGTTATGGGTTCTTACCCAAAGAGTCAAAAACTATTTCTTAAGAAAGAGCAGAGTTATTCATGACTGTTCTTTATACACTAAAAGCAT GCATCTAATCTAATAGTCCTCTTATTATGCTTTTAGTTGTATGAGTCTCTTTCTATGAACTGAACACAAAACTCAGGAATTGGTGGCTTA ATTTTAGATCAGTGCTTGTACTAGGCTTAGTTATATGAATCTTTATAACACATAATTACTAACTTTGTAGCCATATATGTAATTGACTTT GAATGTTATTTACCTGAAATTAATCTTCCTTCACACATGGACCGTAAACGGTTCCCAGTTGTCTGAGAGCCTCATGAGGGTTTCTAGGAT TTATGACCTTATGACCAGTTTTTTTCATTTACCAAGATTTTATTTTCCTACATGAAAATTTAATTGAGTAATAATTATTCACATGTGCAT TTTCTTTTTAGCTGTTAAATGTACTATGCCATCATCCACCATTTAGTAAAATGTAGCTGGCCCAGGACATGTAAAAAAAAAAAAAAAACA ACAACAATAAATAGGGCATGTGAAATGTTAAGTTACAGCAATAGATATTTTATTTGTATTTCATGTTAGTACTTTTTTGTTTTATATCAC TTATAAAGGTACAGTGTACTCTTTGTCACAGCTCAGTTGGTAACCGCATTCCATTGAAAAGTTGGCCTTGTAAAATACAACTCTCATTTA ATATTCATGCTTTTGTGCCTTTAAGAAAATATTTTTTGTCATTTTTTGTGTTACAGAACTATAATGTGATTCAAGGTGTTTATAGGCTTG TCATAAAAGGGTCATTTCTGTGTGTTACTTTCTTTTTATATAGCTATAGTATATTTAAACAATAATACTATCTTTTATAGGGGTTTGTCT ATTTACCTATTCTTTACTCAGACATTGATGTAGACTTGTCAGATTATTCTGAGTATTGTTAACAGTGCCTTTTCGATGGAATCACACTTT TTGGCTGTCACCTTGTGCCATATACACACAAAATTTTGTGGAAGGCAGTTTTAACTTTCTGAAGAATATCTGTCAAAATTTAAGAAAACA AATGTATAAAATTCCATTTTTTCCAGTGTTTAGCATTTCTAGTAAGCAGTGAGGTTGTTTGACATACAGTGATGATGGCATTATTGATAA GCCATACATGAGACTGCAGATTATATTGAATCATATTAAATGTACAGAAATAAAATATTAGATTTATATCAAATTTTCCAATTTGAACCA GTGGGGAAAATCCCACAGAAATCAGTAAGTTTACATTTCAATTTCTATCTTATTTGACTAAGTGGAAAGAGATTCTTTAAAATGTATAAC CTGCCATTATGTAATTTGGTTTCATTTTATTCTACCTGTTGTGTGAGTTTAGTATATTTAATTTACTTTTTGTTACTCTTTACATACTGT TTATTTTTGTTAGTTTTTAATTGAAGATGGACTGTTGAAATTGTATAGGACCAGTGTCTTATTAATATGATTAATATATTTAGAAGAGCC ACGTGAAACCCATGACAAAATGAATGTGAATATTCTTTCTAAAAATTTAGAAAATGTTATCTTTTTGCATTTATTATGTAAAACTGTTTT ACAGTATCAAAATTTTTCACTTAAAGAAAAAAAATGCCATGAAACATTTGAACTGATGAGCCACAGAACTTCAGTTGAAATTTTTTTCAC TTTTTAGCATGCTAAATATACATCTGAGTTTAAATGTTCTGTTTAATGGCCATTCATAAATTCAAGCACTACCACTGGTCAGTTTTGTGT GATAGAATAAAAATATGTTACCTGCAGTGTAAGTACAGCACACTGTCAAATTCTTTTCCTTAAGGTGCACAGTAAATGTACAGATAGTTA TAGGCCACTGTTTTGTAATGTAGTACATTTCTAATCTATTATTCCTAACCTATTATAACTGTTTGCAGAAAGAAAAGAATTTTTCTAATA >8826_8826_4_BACH1-OSBPL8_BACH1_chr21_30702014_ENST00000399921_OSBPL8_chr12_76752591_ENST00000261183_length(amino acids)=709AA_BP=596 MLCRMSLSENSVFAYESSVHSTNVLLSLNDQRKKDVLCDVTIFVEGQRFRAHRSVLAACSSYFHSRIVGQADGELNITLPEEVTVKGFEP LIQFAYTAKLILSKENVDEVCKCVEFLSVHNIEESCFQFLKFKFLDSTADQQECPRKKCFSSHCQKTDLKLSLLDQRDLETDEVEEFLEN KNVQTPQCKLRRYQGNAKASPPLQDSASQTYESMCLEKDAALALPSLCPKYRKFQKAFGTDRVRTGESSVKDIHASVQPNERSENECLGG VPECRDLQVMLKCDESKLAMEPEETKKDPASQCPTEKSEVTPFPHNSSIDPHGLYSLSLLHTYDQYGDLNFAGMQNTTVLTEKPLSGTDV QEKTFGESQDLPLKSDLGTREDSSVASSDRSSVEREVAEHLAKGFWSDICSTDTPCQMQLSPAVAKDGSEQISQKRSECPWLGIRISESP EPGQRTFTTLSSVNCPFISTLSTEGCSSNLEIGNDDYVSEPQQEPCPYACVISLGDDSETDTEGDSESCSAREQECEVKLPFNAQRIISL SRNDFQSLLKMHKLTPEQLDCIHDIRRRSKNRIAAQRCRKRKLDCIQNLESEIEKLVSVPKMKHKPTRQQKKVAKGYSSPEPDIQDSSGS -------------------------------------------------------------- >8826_8826_5_BACH1-OSBPL8_BACH1_chr21_30702014_ENST00000399921_OSBPL8_chr12_76752591_ENST00000393249_length(transcript)=6453nt_BP=2019nt GTCTACTCAGCCCGGTGGCTGTCGCGCGTGGAATCGCGTAAGAAAAGCCGAGTTTGTGGCTGGGGAGAGAAGGCCACCGTGCTGAGCTGG ATTTAGCGAAGACTGGTTTTGGGGACCGGAGAGCCCAGGACTCCCTTTGTTGGAGTTTTGCCCACGCGTTGTAATTAAGCCTCGCACAAT ATGGTTGATGATAATTAGAAGCATGCTTTCCACTGAACTTCCCGACAACATTTGTTATGCAGAATGTCTCTGAGTGAGAACTCGGTTTTT GCCTATGAATCTTCTGTGCATAGCACCAATGTTTTACTCAGCCTTAATGACCAGCGGAAGAAAGATGTGCTGTGCGATGTCACCATCTTT GTGGAGGGACAGCGGTTCCGCGCTCACCGGTCCGTGCTGGCGGCATGCAGCAGTTACTTCCACTCAAGAATCGTAGGCCAGGCTGATGGA GAGCTGAACATTACTCTTCCAGAAGAGGTGACAGTTAAAGGATTTGAACCTTTAATTCAGTTTGCCTACACTGCTAAACTGATTTTAAGT AAAGAGAATGTGGATGAAGTGTGCAAATGTGTGGAGTTTTTAAGTGTACATAATATTGAGGAATCCTGCTTTCAGTTTCTGAAATTTAAG TTTTTGGACTCCACTGCAGACCAGCAAGAATGCCCAAGAAAAAAATGCTTTTCATCACACTGTCAGAAAACAGACCTTAAACTTTCACTT TTGGACCAGAGGGATCTAGAAACTGATGAAGTGGAGGAATTTCTGGAAAATAAAAATGTTCAGACTCCTCAGTGTAAACTCCGCAGGTAT CAAGGAAATGCAAAAGCCTCACCTCCTCTACAAGACAGTGCCAGTCAGACATATGAGTCCATGTGCTTAGAGAAGGATGCTGCTCTGGCC TTGCCTTCTTTATGCCCCAAATACAGAAAATTCCAAAAAGCATTTGGAACTGACAGAGTCCGTACTGGGGAATCTAGTGTCAAAGACATT CATGCTTCTGTTCAGCCAAATGAAAGGTCTGAAAATGAATGCCTGGGAGGAGTCCCGGAGTGTAGAGATTTGCAGGTGATGTTAAAATGT GACGAAAGTAAATTAGCAATGGAACCTGAAGAAACGAAGAAAGATCCTGCTTCTCAGTGCCCAACTGAAAAATCAGAAGTGACTCCTTTC CCCCACAATTCTTCCATAGACCCTCATGGACTTTATTCTTTGTCTCTTTTACACACATATGACCAATATGGTGACTTGAATTTTGCTGGT ATGCAAAACACAACAGTGTTAACAGAAAAGCCTTTGTCAGGTACAGACGTCCAAGAAAAAACATTTGGTGAAAGTCAGGATTTACCTTTG AAATCCGACTTGGGCACCAGGGAAGATAGTAGTGTTGCATCTAGTGATAGGAGTAGTGTGGAGCGAGAAGTGGCAGAACACCTAGCAAAA GGCTTCTGGAGTGACATTTGCAGCACGGACACTCCTTGCCAAATGCAGTTATCACCTGCTGTGGCCAAAGATGGCTCAGAACAGATCTCA CAGAAACGGTCTGAGTGTCCGTGGTTAGGTATCAGGATTAGTGAGAGCCCAGAACCAGGTCAAAGGACTTTCACAACATTAAGTTCTGTC AACTGCCCTTTTATAAGTACTCTGAGTACTGAAGGCTGTTCAAGCAATTTGGAAATTGGAAACGATGATTATGTTTCAGAACCCCAGCAA GAACCTTGCCCATATGCTTGTGTCATTAGCTTGGGAGACGACTCTGAGACGGACACCGAAGGAGACAGTGAATCCTGTTCAGCCAGAGAA CAAGAATGTGAGGTAAAACTGCCATTCAATGCACAACGGATAATTTCACTGTCTCGAAATGATTTTCAGTCCTTGTTGAAAATGCACAAG CTTACTCCAGAACAGCTGGATTGTATCCATGATATTCGAAGAAGAAGTAAAAACAGAATTGCTGCACAGCGCTGTCGCAAGAGAAAACTT GACTGTATACAGAATCTTGAATCAGAAATTGAGAAGCTGGTTAGCGTCCCCAAAATGAAACATAAGCCAACCAGGCAACAGAAGAAAGTA GCAAAAGGCTATTCCTCCCCAGAACCTGACATTCAAGACTCCTCTGGAAGTGAAGCTCAATCAGTAAAACCAAGTACAAGAAGAAAGAAA GGAATAGAACTGGGAGACATTCAGAGTTCCATCGAATCTATAAAACAAACACAGGAAGAAATTAAAAGAAATATTATGGCTCTTCGAAAT CATTTAGTTTCAAGCACACCGGCCACGGATTATTTTCTGCAACAAAAAGACTACTTCATCATTTTCCTCCTGATTTTGCTTCAAGTCATA ATAAACTTCATGTTCAAGTAGAAGTTCTCTACCATTGAATCAGTGAACTAGAAAGATCTGATTTGGCCTGGGACCAGTGTTCAAGTTGGT TTGGTCTTTATTAAAAATCACAATATTCCGAAAACAAAAAAACCTAGGAGATAAATGTAGAGGTATTGACTTTTCGTATCTTTTATCTTC ACACTGAAACAAGAGCTATCCTATTTGATTATTAAAGTGAGCTATGTGTTAAGTGCCAGGACATTTCTAGCTTTTGTGAGAATGTGTCTA CATATGAGTATAATAAACCCACATGTATACACAATTGTCTCTTATGTACTCCTACCTGACAGTAGTCTTTGTATTCTATAGTATGTTCTG AGATATAATGTTAACATTGTTCATAACAAAAAATGCTATCAATCTTATAAATATATGTAATCTATTTTCTTCATAAAACAGGCACAAAAG TTTTATCAGTAAGGAATTACAGATTGAGAAATGATGGAATAATAGACATAATTAATTCAATACACTACTGTTAAAATCATTTGCAAAGCA CTCAGCTCAATTATCTTCTTAGAAAGAAAGAAAAAGTATGAATGGTCAAAATGAATACATCGAGAGAGATAAATGGCAAATTGCTTTTTT AAAAGTTTACATAAGTTTTTTTTAACCCCTAGAATTTAATATTTGTAGATGCAGGTAAATATATATACTTACGTGTATATCAGTATAAAA ACACTGGTGTGCAATTAATTGGATTGATTATAATACCACCTTAAGCACTTGCTGAAAAAAGTGTGGTCAAAATTGATTGCTGTCCTTTTG TCTTATTTTTGTTTTTCTTAAGTCAGCTGGTTCATAACATAGGCCAAATTCTAGAGATGTTTATAGAGCATTTGAAGTGCTGATAATTTA TGTTTTTTCATTATGAAAACTTATTTTAGCTTTAGACTCCAGTGTGTTCAGTGAATAAGTAGAATATAAAAAAATATAACCAGTATTTTA CTTCAAAAGCCAAAAAGAGGCAATAAGAAAAGACACTTTGTGGTGGCCTTTATGTGTGCATTAAAATTGGTTTCTGTAAAACGTGTAATA AGTTGAGTATCTACGAAGAGTATCAAGTTCTGAAGTTTAATTTTTTTATTATCCTCCTCTCTTCTTAGTAACTTCTTTCTGTGGCAAAAC CACAATTCTTTAAGATTCCTATTGTTCAGGCTAAGGCAAATTTTTTTGTTTGTTTCTTCAGTTTAATATTTTGATTTTGTGTTTTTACGT AAATATTTATATTCCTTGAAAGCAATTTTTGCCAAGGTAGTTCAGTTTAGGAATATGTTGTTCTAAAATATGTCTTAGAATCCTGAAAGC ATAGATTTTGAAATGTTTTTTTAATGAAAATGAAGGTCAGAGAGAATAATTGCCCTGACCACATTTGCCTTTCAGTAGGAGGAGGCTGTG AAATAGTAAAATTATAATCGTTTATGCCATGATAAATACAAGATTGGTAAATAAATACATTGATTGGTAAATTATGAGAATCAAAATGAT AAAAAGAGCCTGCTTTTTTCCCTAACCAATATAGCTATCTTAAGTATCCTTAGGTTTCTGTGAAGAACCATTTCCCATGTTTTCTTGGCA AAATAATGCTGTATTCCATATGTACATGTGAAATGATGTTTTAAATTGATAAAAGCTTAAATAAGATCTACCTATACCCAGTATTTTCAT GATATTAGAACAAATGGGTTTTTGGTTATATTTTATATTTGTCAATATAATTTTTGTATTCACATTCTGTTACACTCTGCCTATTCATTG ATATATGATATTCTGTAAATATTGTACAATTTGATCTTTTTTATGGTTTAAATTAGTTAATTACATACAAATTGATTGGCTTATCACAAA AATCATTTCATCAGTAAACCTTGTTAACATTTTGTACTGGTGACCCACCTCTTAGGACTTTGGTCTTATCCACGTGTATGTTGTTTTCAT TTGGTCCAAATAATATTTTATTTGTATGGGTATCTTCTAAGACTAAATAGGTAGTTGTGTTCTTTATTTTTAAAATTTCTTTTTAGAGCA AATGTTATGGGTTCTTACCCAAAGAGTCAAAAACTATTTCTTAAGAAAGAGCAGAGTTATTCATGACTGTTCTTTATACACTAAAAGCAT GCATCTAATCTAATAGTCCTCTTATTATGCTTTTAGTTGTATGAGTCTCTTTCTATGAACTGAACACAAAACTCAGGAATTGGTGGCTTA ATTTTAGATCAGTGCTTGTACTAGGCTTAGTTATATGAATCTTTATAACACATAATTACTAACTTTGTAGCCATATATGTAATTGACTTT GAATGTTATTTACCTGAAATTAATCTTCCTTCACACATGGACCGTAAACGGTTCCCAGTTGTCTGAGAGCCTCATGAGGGTTTCTAGGAT TTATGACCTTATGACCAGTTTTTTTCATTTACCAAGATTTTATTTTCCTACATGAAAATTTAATTGAGTAATAATTATTCACATGTGCAT TTTCTTTTTAGCTGTTAAATGTACTATGCCATCATCCACCATTTAGTAAAATGTAGCTGGCCCAGGACATGTAAAAAAAAAAAAAAAACA ACAACAATAAATAGGGCATGTGAAATGTTAAGTTACAGCAATAGATATTTTATTTGTATTTCATGTTAGTACTTTTTTGTTTTATATCAC TTATAAAGGTACAGTGTACTCTTTGTCACAGCTCAGTTGGTAACCGCATTCCATTGAAAAGTTGGCCTTGTAAAATACAACTCTCATTTA ATATTCATGCTTTTGTGCCTTTAAGAAAATATTTTTTGTCATTTTTTGTGTTACAGAACTATAATGTGATTCAAGGTGTTTATAGGCTTG TCATAAAAGGGTCATTTCTGTGTGTTACTTTCTTTTTATATAGCTATAGTATATTTAAACAATAATACTATCTTTTATAGGGGTTTGTCT ATTTACCTATTCTTTACTCAGACATTGATGTAGACTTGTCAGATTATTCTGAGTATTGTTAACAGTGCCTTTTCGATGGAATCACACTTT TTGGCTGTCACCTTGTGCCATATACACACAAAATTTTGTGGAAGGCAGTTTTAACTTTCTGAAGAATATCTGTCAAAATTTAAGAAAACA AATGTATAAAATTCCATTTTTTCCAGTGTTTAGCATTTCTAGTAAGCAGTGAGGTTGTTTGACATACAGTGATGATGGCATTATTGATAA GCCATACATGAGACTGCAGATTATATTGAATCATATTAAATGTACAGAAATAAAATATTAGATTTATATCAAATTTTCCAATTTGAACCA GTGGGGAAAATCCCACAGAAATCAGTAAGTTTACATTTCAATTTCTATCTTATTTGACTAAGTGGAAAGAGATTCTTTAAAATGTATAAC CTGCCATTATGTAATTTGGTTTCATTTTATTCTACCTGTTGTGTGAGTTTAGTATATTTAATTTACTTTTTGTTACTCTTTACATACTGT TTATTTTTGTTAGTTTTTAATTGAAGATGGACTGTTGAAATTGTATAGGACCAGTGTCTTATTAATATGATTAATATATTTAGAAGAGCC ACGTGAAACCCATGACAAAATGAATGTGAATATTCTTTCTAAAAATTTAGAAAATGTTATCTTTTTGCATTTATTATGTAAAACTGTTTT ACAGTATCAAAATTTTTCACTTAAAGAAAAAAAATGCCATGAAACATTTGAACTGATGAGCCACAGAACTTCAGTTGAAATTTTTTTCAC TTTTTAGCATGCTAAATATACATCTGAGTTTAAATGTTCTGTTTAATGGCCATTCATAAATTCAAGCACTACCACTGGTCAGTTTTGTGT GATAGAATAAAAATATGTTACCTGCAGTGTAAGTACAGCACACTGTCAAATTCTTTTCCTTAAGGTGCACAGTAAATGTACAGATAGTTA TAGGCCACTGTTTTGTAATGTAGTACATTTCTAATCTATTATTCCTAACCTATTATAACTGTTTGCAGAAAGAAAAGAATTTTTCTAATA >8826_8826_5_BACH1-OSBPL8_BACH1_chr21_30702014_ENST00000399921_OSBPL8_chr12_76752591_ENST00000393249_length(amino acids)=709AA_BP=596 MLCRMSLSENSVFAYESSVHSTNVLLSLNDQRKKDVLCDVTIFVEGQRFRAHRSVLAACSSYFHSRIVGQADGELNITLPEEVTVKGFEP LIQFAYTAKLILSKENVDEVCKCVEFLSVHNIEESCFQFLKFKFLDSTADQQECPRKKCFSSHCQKTDLKLSLLDQRDLETDEVEEFLEN KNVQTPQCKLRRYQGNAKASPPLQDSASQTYESMCLEKDAALALPSLCPKYRKFQKAFGTDRVRTGESSVKDIHASVQPNERSENECLGG VPECRDLQVMLKCDESKLAMEPEETKKDPASQCPTEKSEVTPFPHNSSIDPHGLYSLSLLHTYDQYGDLNFAGMQNTTVLTEKPLSGTDV QEKTFGESQDLPLKSDLGTREDSSVASSDRSSVEREVAEHLAKGFWSDICSTDTPCQMQLSPAVAKDGSEQISQKRSECPWLGIRISESP EPGQRTFTTLSSVNCPFISTLSTEGCSSNLEIGNDDYVSEPQQEPCPYACVISLGDDSETDTEGDSESCSAREQECEVKLPFNAQRIISL SRNDFQSLLKMHKLTPEQLDCIHDIRRRSKNRIAAQRCRKRKLDCIQNLESEIEKLVSVPKMKHKPTRQQKKVAKGYSSPEPDIQDSSGS -------------------------------------------------------------- >8826_8826_6_BACH1-OSBPL8_BACH1_chr21_30702014_ENST00000399921_OSBPL8_chr12_76752591_ENST00000393250_length(transcript)=2414nt_BP=2019nt GTCTACTCAGCCCGGTGGCTGTCGCGCGTGGAATCGCGTAAGAAAAGCCGAGTTTGTGGCTGGGGAGAGAAGGCCACCGTGCTGAGCTGG ATTTAGCGAAGACTGGTTTTGGGGACCGGAGAGCCCAGGACTCCCTTTGTTGGAGTTTTGCCCACGCGTTGTAATTAAGCCTCGCACAAT ATGGTTGATGATAATTAGAAGCATGCTTTCCACTGAACTTCCCGACAACATTTGTTATGCAGAATGTCTCTGAGTGAGAACTCGGTTTTT GCCTATGAATCTTCTGTGCATAGCACCAATGTTTTACTCAGCCTTAATGACCAGCGGAAGAAAGATGTGCTGTGCGATGTCACCATCTTT GTGGAGGGACAGCGGTTCCGCGCTCACCGGTCCGTGCTGGCGGCATGCAGCAGTTACTTCCACTCAAGAATCGTAGGCCAGGCTGATGGA GAGCTGAACATTACTCTTCCAGAAGAGGTGACAGTTAAAGGATTTGAACCTTTAATTCAGTTTGCCTACACTGCTAAACTGATTTTAAGT AAAGAGAATGTGGATGAAGTGTGCAAATGTGTGGAGTTTTTAAGTGTACATAATATTGAGGAATCCTGCTTTCAGTTTCTGAAATTTAAG TTTTTGGACTCCACTGCAGACCAGCAAGAATGCCCAAGAAAAAAATGCTTTTCATCACACTGTCAGAAAACAGACCTTAAACTTTCACTT TTGGACCAGAGGGATCTAGAAACTGATGAAGTGGAGGAATTTCTGGAAAATAAAAATGTTCAGACTCCTCAGTGTAAACTCCGCAGGTAT CAAGGAAATGCAAAAGCCTCACCTCCTCTACAAGACAGTGCCAGTCAGACATATGAGTCCATGTGCTTAGAGAAGGATGCTGCTCTGGCC TTGCCTTCTTTATGCCCCAAATACAGAAAATTCCAAAAAGCATTTGGAACTGACAGAGTCCGTACTGGGGAATCTAGTGTCAAAGACATT CATGCTTCTGTTCAGCCAAATGAAAGGTCTGAAAATGAATGCCTGGGAGGAGTCCCGGAGTGTAGAGATTTGCAGGTGATGTTAAAATGT GACGAAAGTAAATTAGCAATGGAACCTGAAGAAACGAAGAAAGATCCTGCTTCTCAGTGCCCAACTGAAAAATCAGAAGTGACTCCTTTC CCCCACAATTCTTCCATAGACCCTCATGGACTTTATTCTTTGTCTCTTTTACACACATATGACCAATATGGTGACTTGAATTTTGCTGGT ATGCAAAACACAACAGTGTTAACAGAAAAGCCTTTGTCAGGTACAGACGTCCAAGAAAAAACATTTGGTGAAAGTCAGGATTTACCTTTG AAATCCGACTTGGGCACCAGGGAAGATAGTAGTGTTGCATCTAGTGATAGGAGTAGTGTGGAGCGAGAAGTGGCAGAACACCTAGCAAAA GGCTTCTGGAGTGACATTTGCAGCACGGACACTCCTTGCCAAATGCAGTTATCACCTGCTGTGGCCAAAGATGGCTCAGAACAGATCTCA CAGAAACGGTCTGAGTGTCCGTGGTTAGGTATCAGGATTAGTGAGAGCCCAGAACCAGGTCAAAGGACTTTCACAACATTAAGTTCTGTC AACTGCCCTTTTATAAGTACTCTGAGTACTGAAGGCTGTTCAAGCAATTTGGAAATTGGAAACGATGATTATGTTTCAGAACCCCAGCAA GAACCTTGCCCATATGCTTGTGTCATTAGCTTGGGAGACGACTCTGAGACGGACACCGAAGGAGACAGTGAATCCTGTTCAGCCAGAGAA CAAGAATGTGAGGTAAAACTGCCATTCAATGCACAACGGATAATTTCACTGTCTCGAAATGATTTTCAGTCCTTGTTGAAAATGCACAAG CTTACTCCAGAACAGCTGGATTGTATCCATGATATTCGAAGAAGAAGTAAAAACAGAATTGCTGCACAGCGCTGTCGCAAGAGAAAACTT GACTGTATACAGAATCTTGAATCAGAAATTGAGAAGCTGGTTAGCGTCCCCAAAATGAAACATAAGCCAACCAGGCAACAGAAGAAAGTA GCAAAAGGCTATTCCTCCCCAGAACCTGACATTCAAGACTCCTCTGGAAGTGAAGCTCAATCAGTAAAACCAAGTACAAGAAGAAAGAAA GGAATAGAACTGGGAGACATTCAGAGTTCCATCGAATCTATAAAACAAACACAGGAAGAAATTAAAAGAAATATTATGGCTCTTCGAAAT CATTTAGTTTCAAGCACACCGGCCACGGATTATTTTCTGCAACAAAAAGACTACTTCATCATTTTCCTCCTGATTTTGCTTCAAGTCATA >8826_8826_6_BACH1-OSBPL8_BACH1_chr21_30702014_ENST00000399921_OSBPL8_chr12_76752591_ENST00000393250_length(amino acids)=709AA_BP=596 MLCRMSLSENSVFAYESSVHSTNVLLSLNDQRKKDVLCDVTIFVEGQRFRAHRSVLAACSSYFHSRIVGQADGELNITLPEEVTVKGFEP LIQFAYTAKLILSKENVDEVCKCVEFLSVHNIEESCFQFLKFKFLDSTADQQECPRKKCFSSHCQKTDLKLSLLDQRDLETDEVEEFLEN KNVQTPQCKLRRYQGNAKASPPLQDSASQTYESMCLEKDAALALPSLCPKYRKFQKAFGTDRVRTGESSVKDIHASVQPNERSENECLGG VPECRDLQVMLKCDESKLAMEPEETKKDPASQCPTEKSEVTPFPHNSSIDPHGLYSLSLLHTYDQYGDLNFAGMQNTTVLTEKPLSGTDV QEKTFGESQDLPLKSDLGTREDSSVASSDRSSVEREVAEHLAKGFWSDICSTDTPCQMQLSPAVAKDGSEQISQKRSECPWLGIRISESP EPGQRTFTTLSSVNCPFISTLSTEGCSSNLEIGNDDYVSEPQQEPCPYACVISLGDDSETDTEGDSESCSAREQECEVKLPFNAQRIISL SRNDFQSLLKMHKLTPEQLDCIHDIRRRSKNRIAAQRCRKRKLDCIQNLESEIEKLVSVPKMKHKPTRQQKKVAKGYSSPEPDIQDSSGS -------------------------------------------------------------- |
Top |
Fusion Gene PPI Analysis for BACH1-OSBPL8 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
Top |
Related Drugs for BACH1-OSBPL8 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
Related Diseases for BACH1-OSBPL8 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | C0043094 | Weight Gain | 1 | CTD_human |
Copyright 2021-Present -The University of Texas Health Science Center at Houston (UTHealth)
Web File Viewing | Emergency Information |Campus Carry|Site Policies