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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:RNF213-CSNK1D (FusionGDB2 ID:HG57674TG1453)

Fusion Gene Summary for RNF213-CSNK1D

check button Fusion gene summary
Fusion gene informationFusion gene name: RNF213-CSNK1D
Fusion gene ID: hg57674tg1453
HgeneTgene
Gene symbol

RNF213

CSNK1D

Gene ID

57674

1453

Gene namering finger protein 213casein kinase 1 delta
SynonymsALO17|C17orf27|KIAA1618|MYMY2|MYSTR|NET57ASPS|CKI-delta|CKId|CKIdelta|FASPS2|HCKID
Cytomap('RNF213')('CSNK1D')

17q25.3

17q25.3

Type of geneprotein-codingprotein-coding
DescriptionE3 ubiquitin-protein ligase RNF213ALK lymphoma oligomerization partner on chromosome 17RING-type E3 ubiquitin transferase RNF213mysterincasein kinase I isoform deltacasein kinase Itau-protein kinase CSNK1D
Modification date2020031320200313
UniProtAcc

Q63HN8

.
Ensembl transtripts involved in fusion geneENST00000336301, ENST00000508628, 
ENST00000582970, ENST00000319921, 
ENST00000427003, ENST00000456466, 
ENST00000319921, ENST00000336301, 
ENST00000427003, ENST00000456466, 
ENST00000582970, ENST00000508628, 
Fusion gene scores* DoF score34 X 32 X 16=1740820 X 19 X 9=3420
# samples 4122
** MAII scorelog2(41/17408*10)=-5.40798274174489
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(22/3420*10)=-3.9584208962486
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: RNF213 [Title/Abstract] AND CSNK1D [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointRNF213(78354787)-CSNK1D(80211120), # samples:2
Anticipated loss of major functional domain due to fusion event.RNF213-CSNK1D seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
RNF213-CSNK1D seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
RNF213-CSNK1D seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
RNF213-CSNK1D seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
CSNK1D-RNF213 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
CSNK1D-RNF213 seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
CSNK1D-RNF213 seems lost the major protein functional domain in Hgene partner, which is a kinase due to the frame-shifted ORF.
CSNK1D-RNF213 seems lost the major protein functional domain in Tgene partner, which is a CGC due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneRNF213

GO:0016567

protein ubiquitination

21799892

HgeneRNF213

GO:0051260

protein homooligomerization

24658080|26126547

HgeneRNF213

GO:0051865

protein autoubiquitination

21799892

TgeneCSNK1D

GO:0006468

protein phosphorylation

16618118

TgeneCSNK1D

GO:0018105

peptidyl-serine phosphorylation

25500533

TgeneCSNK1D

GO:0051225

spindle assembly

10826492


check buttonFusion gene breakpoints across RNF213 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across CSNK1D (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4HNSCTCGA-CV-7414RNF213chr17

78354787

+CSNK1Dchr17

80211120

-


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Fusion Gene ORF analysis for RNF213-CSNK1D

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000336301ENST00000578904RNF213chr17

78354787

+CSNK1Dchr17

80211120

-
5CDS-5UTRENST00000508628ENST00000578904RNF213chr17

78354787

+CSNK1Dchr17

80211120

-
5CDS-5UTRENST00000582970ENST00000578904RNF213chr17

78354787

+CSNK1Dchr17

80211120

-
In-frameENST00000336301ENST00000314028RNF213chr17

78354787

+CSNK1Dchr17

80211120

-
In-frameENST00000336301ENST00000392334RNF213chr17

78354787

+CSNK1Dchr17

80211120

-
In-frameENST00000336301ENST00000398519RNF213chr17

78354787

+CSNK1Dchr17

80211120

-
In-frameENST00000508628ENST00000314028RNF213chr17

78354787

+CSNK1Dchr17

80211120

-
In-frameENST00000508628ENST00000392334RNF213chr17

78354787

+CSNK1Dchr17

80211120

-
In-frameENST00000508628ENST00000398519RNF213chr17

78354787

+CSNK1Dchr17

80211120

-
In-frameENST00000582970ENST00000314028RNF213chr17

78354787

+CSNK1Dchr17

80211120

-
In-frameENST00000582970ENST00000392334RNF213chr17

78354787

+CSNK1Dchr17

80211120

-
In-frameENST00000582970ENST00000398519RNF213chr17

78354787

+CSNK1Dchr17

80211120

-
intron-3CDSENST00000319921ENST00000314028RNF213chr17

78354787

+CSNK1Dchr17

80211120

-
intron-3CDSENST00000319921ENST00000392334RNF213chr17

78354787

+CSNK1Dchr17

80211120

-
intron-3CDSENST00000319921ENST00000398519RNF213chr17

78354787

+CSNK1Dchr17

80211120

-
intron-3CDSENST00000427003ENST00000314028RNF213chr17

78354787

+CSNK1Dchr17

80211120

-
intron-3CDSENST00000427003ENST00000392334RNF213chr17

78354787

+CSNK1Dchr17

80211120

-
intron-3CDSENST00000427003ENST00000398519RNF213chr17

78354787

+CSNK1Dchr17

80211120

-
intron-3CDSENST00000456466ENST00000314028RNF213chr17

78354787

+CSNK1Dchr17

80211120

-
intron-3CDSENST00000456466ENST00000392334RNF213chr17

78354787

+CSNK1Dchr17

80211120

-
intron-3CDSENST00000456466ENST00000398519RNF213chr17

78354787

+CSNK1Dchr17

80211120

-
intron-5UTRENST00000319921ENST00000578904RNF213chr17

78354787

+CSNK1Dchr17

80211120

-
intron-5UTRENST00000427003ENST00000578904RNF213chr17

78354787

+CSNK1Dchr17

80211120

-
intron-5UTRENST00000456466ENST00000578904RNF213chr17

78354787

+CSNK1Dchr17

80211120

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000508628RNF213chr1778354787+ENST00000398519CSNK1Dchr1780211120-1528614089145150364963
ENST00000508628RNF213chr1778354787+ENST00000314028CSNK1Dchr1780211120-1711514089145150004951
ENST00000508628RNF213chr1778354787+ENST00000392334CSNK1Dchr1780211120-1548414089145149824945
ENST00000582970RNF213chr1778354787+ENST00000398519CSNK1Dchr1780211120-1513713940143148874914
ENST00000582970RNF213chr1778354787+ENST00000314028CSNK1Dchr1780211120-1696613940143148514902
ENST00000582970RNF213chr1778354787+ENST00000392334CSNK1Dchr1780211120-1533513940143148334896
ENST00000336301RNF213chr1778354787+ENST00000398519CSNK1Dchr1780211120-92138016089632987
ENST00000336301RNF213chr1778354787+ENST00000314028CSNK1Dchr1780211120-110428016089272975
ENST00000336301RNF213chr1778354787+ENST00000392334CSNK1Dchr1780211120-94118016089092969

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000508628ENST00000398519RNF213chr1778354787+CSNK1Dchr1780211120-0.0025648750.99743515
ENST00000508628ENST00000314028RNF213chr1778354787+CSNK1Dchr1780211120-0.0026672050.9973328
ENST00000508628ENST00000392334RNF213chr1778354787+CSNK1Dchr1780211120-0.0023240470.99767596
ENST00000582970ENST00000398519RNF213chr1778354787+CSNK1Dchr1780211120-0.0024192230.99758077
ENST00000582970ENST00000314028RNF213chr1778354787+CSNK1Dchr1780211120-0.0025223610.9974776
ENST00000582970ENST00000392334RNF213chr1778354787+CSNK1Dchr1780211120-0.0022033460.99779665
ENST00000336301ENST00000398519RNF213chr1778354787+CSNK1Dchr1780211120-0.0019834430.9980166
ENST00000336301ENST00000314028RNF213chr1778354787+CSNK1Dchr1780211120-0.0017555650.9982444
ENST00000336301ENST00000392334RNF213chr1778354787+CSNK1Dchr1780211120-0.0017836080.99821633

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Fusion Genomic Features for RNF213-CSNK1D


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for RNF213-CSNK1D


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr17:78354787/chr17:80211120)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
RNF213

Q63HN8

.
FUNCTION: Atypical E3 ubiquitin ligase that can catalyze ubiquitination of both proteins and lipids, and which is involved in various processes, such as lipid metabolism, angiogenesis and cell-autonomous immunity (PubMed:21799892, PubMed:26126547, PubMed:26278786, PubMed:26766444, PubMed:30705059, PubMed:32139119, PubMed:34012115). Acts as a key immune sensor by catalyzing ubiquitination of the lipid A moiety of bacterial lipopolysaccharide (LPS) via its RZ-type zinc-finger: restricts the proliferation of cytosolic bacteria, such as Salmonella, by generating the bacterial ubiquitin coat through the ubiquitination of LPS (PubMed:34012115). Also acts indirectly by mediating the recruitment of the LUBAC complex, which conjugates linear polyubiquitin chains (PubMed:34012115). Ubiquitination of LPS triggers cell-autonomous immunity, such as antibacterial autophagy, leading to degradation of the microbial invader (PubMed:34012115). Involved in lipid metabolism by regulating fat storage and lipid droplet formation; act by inhibiting the lipolytic process (PubMed:30705059). Also regulates lipotoxicity by inhibiting desaturation of fatty acids (PubMed:30846318). Also acts as an E3 ubiquitin-protein ligase via its RING-type zinc finger: mediates 'Lys-63'-linked ubiquitination of target proteins (PubMed:32139119, PubMed:33842849). Involved in the non-canonical Wnt signaling pathway in vascular development: acts by mediating ubiquitination and degradation of FLNA and NFATC2 downstream of RSPO3, leading to inhibit the non-canonical Wnt signaling pathway and promoting vessel regression (PubMed:26766444). Also has ATPase activity; ATPase activity is required for ubiquitination of LPS (PubMed:34012115). {ECO:0000269|PubMed:21799892, ECO:0000269|PubMed:26126547, ECO:0000269|PubMed:26278786, ECO:0000269|PubMed:26766444, ECO:0000269|PubMed:30705059, ECO:0000269|PubMed:30846318, ECO:0000269|PubMed:32139119, ECO:0000269|PubMed:33842849, ECO:0000269|PubMed:34012115}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneRNF213chr17:78354787chr17:80211120ENST00000508628+5769343_37446485257.0Coiled coilOntology_term=ECO:0000255
HgeneRNF213chr17:78354787chr17:80211120ENST00000582970+5668343_37445995208.0Coiled coilOntology_term=ECO:0000255
HgeneRNF213chr17:78354787chr17:80211120ENST00000508628+57693997_403646485257.0Zinc fingerRING-type
HgeneRNF213chr17:78354787chr17:80211120ENST00000582970+56683997_403645995208.0Zinc fingerRING-type
TgeneCSNK1Dchr17:78354787chr17:80211120ENST0000031402829278_364112416.0RegionNote=Centrosomal localization signal (CLS)
TgeneCSNK1Dchr17:78354787chr17:80211120ENST0000031402829317_342112416.0RegionAutoinhibitory
TgeneCSNK1Dchr17:78354787chr17:80211120ENST00000392334210278_364112420.3333333333333RegionNote=Centrosomal localization signal (CLS)
TgeneCSNK1Dchr17:78354787chr17:80211120ENST00000392334210317_342112420.3333333333333RegionAutoinhibitory

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneRNF213chr17:78354787chr17:80211120ENST00000319921+117343_37401064.0Coiled coilOntology_term=ECO:0000255
HgeneRNF213chr17:78354787chr17:80211120ENST00000319921+1173997_403601064.0Zinc fingerRING-type
TgeneCSNK1Dchr17:78354787chr17:80211120ENST00000314028299_277112416.0DomainProtein kinase
TgeneCSNK1Dchr17:78354787chr17:80211120ENST000003923342109_277112420.3333333333333DomainProtein kinase
TgeneCSNK1Dchr17:78354787chr17:80211120ENST000003140282915_23112416.0Nucleotide bindingATP
TgeneCSNK1Dchr17:78354787chr17:80211120ENST0000039233421015_23112420.3333333333333Nucleotide bindingATP


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Fusion Gene Sequence for RNF213-CSNK1D


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>74967_74967_1_RNF213-CSNK1D_RNF213_chr17_78354787_ENST00000336301_CSNK1D_chr17_80211120_ENST00000314028_length(transcript)=11042nt_BP=8016nt
ATGGTCTGTGATGGGGACTGGGAGCACTGCTACCTCCCCTCTGCCTTCAGCCAGCACAAGGTCTTCGTCACCCCCCAGGCACCCCTCGAG
GCCATCCAAGCCTACCTGGCAGGTCACTACCGGGTCCCGAAGCAGACCCTGTCGGCGGCAGCCGTGTTCAATGACCGGCTGTGTGTTGGG
ATCGTGGCCTCGGAGCGAGCAGGTGTTGGAAAGTCTCTGTACGTGAAGAGGTTGCACGACAAAATGAAGATGCAGTTAAACGTGAAAAAT
GTGCCTCTGAAAACAATTCGACTGATCGACCCTCAGGTGGATGAGAGCCGAGTCCTGGGCGCCCTGCTGCCCTTCCTGGATGCGCAGTAT
CAGAAGGTCCCCGTGCTCTTTCACCTGGACGTGACCTCCTCAGTGCAGACTGGAATTTGGGTGTTTCTTTTCAAGCTCCTCATTTTACAA
TACTTAATGGATATAAATGGGAAAATGTGGCTTCGGAACCCCTGCCATTTGTATATCGTTGAAATCCTGGAAAGGAGGACGTCAGTGCCG
TCGAGGAGCTCTTCAGCGCTGCGTACACGTGTACCCCAGTTCAGTTTTCTTGACATCTTCCCAAAAGTCACCTGCAGGCCTCCCAAAGAG
GTGATAGACATGGAGCTGAGTGCCCTGAGGAGTGACACAGAGCCTGGGATGGATCTGTGGGAGTTCTGCAGCGAAACTTTCCAAAGACCT
TACCAGTATTTAAGACGATTCAATCAAAACCAAGACCTAGACACGTTTCAGTATCAAGAAGGCTCTGTCGAAGGCACCCCGGAGGAATGC
CTCCAGCATTTCCTGTTTCACTGCGGGGTAATAAACCCATCCTGGTCAGAGCTTCGGAACTTTGCTCGGTTCCTGAATTATCAGCTCAGA
GATTGTGAGGCCTCTCTCTTCTGCAATCCGAGTTTTATTGGCGACACACTGAGGGGCTTCAAGAAGTTCGTGGTGACCTTCATGATCTTT
ATGGCAAGAGATTTTGCCACACCATCACTCCACACCTCTGACCAAAGCCCGGGGAAGCACATGGTCACCATGGATGGGGTTAGGGAAGAA
GATCTAGCGCCCTTCTCCCTCCGGAAGAGGTGGGAGTCGGAGCCTCACCCATACGTTTTCTTCAATGACGACCACACAACCATGACATTC
ATCGGCTTCCATCTGCAGCCCAACATCAACGGCAGTGTCGATGCCATCAGTCACTTGACTGGGAAGGTCATCAAGAGAGACGTCATGACC
AGGGACCTGTACCAGGGCCTGCTGCTCCAGAGGGTGCCCTTCAATGTCGACTTTGATAAACTGCCCAGACACAAGAAACTTGAGAGGCTC
TGCCTGACCTTAGGGATCCCCCAGGCCACCGACCCCGACAAAACGTATGAGCTCACAACCGACAATATGCTTAAAATCCTTGCCATCGAG
ATGCGGTTCCGGTGTGGGATCCCGGTTATCATCATGGGAGAAACTGGCTGTGGGAAAACCAGGCTTATTAAATTCCTTAGCGACCTGCGG
CGTGGTGGTACCAATGCTGACACCATAAAGCTGGTCAAGGTGCACGGAGGAACAACTGCAGACATGATCTACTCCAGAGTCAGGGAGGCT
GAAAATGTGGCCTTCGCCAATAAGGACCAACATCAGTTGGACACCATCTTGTTTTTTGATGAAGCCAACACAACGGAAGCTATAAGCTGT
ATCAAAGAAGTCCTGTGTGATCATATGGTGGATGGCCAGCCTCTGGCTGAGGACTCTGGCCTGCATATTATAGCTGCCTGCAATCCATAC
CGGAAGCACTCTGAGGAGATGATCTGCCGTTTGGAGTCAGCTGGTTTGGGCTACAGGGTTAGTATGGAGGAGACGGCCGACAGGCTGGGC
TCCATTCCTCTGAGGCAGCTGGTATACCGGGTCCATGCTCTGCCCCCGAGCCTGATTCCTCTGGTGTGGGACTTTGGACAACTGAGTGAC
GTTGCTGAAAAGCTCTACATCCAGCAGATTGTCCAGAGACTGGTTGAGTCCATCAGCCTAGATGAAAACGGGACTCGCGTGATCACAGAA
GTCCTCTGCGCCTCTCAGGGTTTCATGAGGAAAACAGAAGATGAGTGCAGCTTTGTCAGCCTCAGGGACGTGGAGCGCTGTGTGAAAGTT
TTCAGGTGGTTCCACGAGCACAGCGCGATGCTCTTAGCGCAGCTGAATGCCTTTCTCTCCAAGTCCAGCGTCAGCAAAAATCACACCGAG
AGAGATCCCGTCCTCTGGTCGTTGATGCTGGCCATCGGGGTGTGTTACCATGCCTCTTTAGAAAAGAAAGACTCATATCGGAAAGCCATC
GCCAGGTTCTTTCCGAAACCGTATGACGACAGCAGGCTGCTTCTGGATGAAATAACACGGGCACAGGATCTTTTTCTGGACGGCGTACCT
CTGAGGAAAACCATCGCCAAGAACTTGGCCTTGAAGGAGAACGTCTTCATGATGGTCGTCTGCATCGAGCTGAAGATTCCCCTCTTCCTG
GTGGGGAAGCCCGGCAGCTCCAAGTCTCTCGCCAAGACCATCGTGGCAGACGCCATGCAGGGCCCGGCTGCCTACTCAGATCTCTTCCGC
AGCCTGAAGCAGGTCCACCTGGTGTCCTTCCAGTGCAGCCCGCACTCCACCCCACAGGGCATCATCAGCACCTTCCGGCAGTGCGCCCGC
TTTCAGCAGGGGAAGGACCTGCAGCAGTACGTCTCTGTGGTGGTGTTAGATGAGGTGGGGCTGGCGGAAGACTCACCCAAAATGCCCCTG
AAGACTCTGCACCCGCTGCTGGAAGACGGATGCATTGAAGACGATCCCGCCCCCCACAAAAAGGTCGGCTTCGTGGGCATCTCCAACTGG
GCCCTTGACCCTGCCAAGATGAACCGGGGCATTTTTGTGTCACGTGGCAGCCCCAACGAGACAGAGCTCATAGAGAGCGCCAAGGGCATC
TGCTCCTCAGACATCCTCGTCCAGGACCGAGTCCAAGGGTACTTTGCGTCCTTTGCCAAAGCCTACGAAACGGTGTGTAAGCGCCAGGAC
AAGGAATTCTTCGGGCTTCGTGACTACTACAGCCTCATCAAAATGGTCTTTGCTGCAGCAAAGGCTTCAAATAGAAAGCCTTCCCCGCAA
GACATTGCACAGGCTGTCCTTAGGAACTTCAGTGGCAAGGATGACATCCAAGCTTTGGACATCTTTCTGGCCAATTTGCCCGAGGCCAAG
TGCTCAGAGGAAGTCAGCCCCATGCAGCTGATCAAACAGAACATCTTTGGGCCTTCTCAGAAGGTGCCGGGTGGAGAGCAGGAAGATGCT
GAGTCCCGCTACTTACTCGTGCTGACCAAAAACTACGTGGCACTGCAGATCCTGCAGCAGACATTCTTCGAGGGGGACCAGCAGCCGGAG
ATTATTTTTGGTTCTGGTTTCCCCAAGGACCAAGAGTACACCCAGCTCTGCAGAAACATCAATCGTGTGAAGATCTGCATGGAAACAGGC
AAGATGGTGTTGCTTCTCAACCTGCAGAACCTCTACGAGAGCCTCTACGACGCACTCAACCAGTACTACGTCCACCTCGGCGGCCAGAAG
TACGTGGACCTCGGTCTGGGGACCCACCGCGTCAAATGTCGGGTTCACCCCAACTTCCGCCTGATTGTCATTGAAGAGAAAGACGTCGTG
TACAAACACTTTCCCATCCCCCTCATTAACCGGCTGGAGAAGCACTATCTGGATATCAACACGGTGCTGGAGAAATGGCAGAAGAGCATC
GTGGAGGAGCTCTGTGCGTGGGTGGAGAAGTTCATCAATGTCAAAGCACATCATTTCCAGAAGAGGCACAAATACAGCCCCTCTGACGTC
TTCATCGGCTACCACTCGGACGCCTGCGCGTCTGTGGTGCTGCAGGTCATAGAGAGGCAGGGTCCCCGGGCCTTGACGGAGGAACTTCAC
CAGAAGGTGTCTGAGGAGGCCAAATCGATCCTGCTGAACTGCGCTACGCCCGATGCCGTGGTCCGGCTGAGCGCCTACTCGCTGGGCGGG
TTCGCAGCGGAGTGGCTGTCGCAGGAGTACTTTCACAGACAGAGGCACAACTCCTTTGCAGATTTCCTTCAGGCACACCTGCACACGGCA
GACCTGGAGCGCCACGCCATCTTCACAGAGATCACCACTTTCTCCAGGCTGCTAACAAGTCACGACTGTGAAATTTTAGAATCAGAGGTC
ACAGGCAGGGCTCCGAAACCCACACTCCTGTGGCTGCAGCAGTTTGACACCGAGTACTCATTCCTCAAAGAAGTCCGAAACTGTTTAACG
AATACAGCCAAATGTAAAATCCTCATTTTTCAGACAGATTTTGAAGATGGAATCCGTAGCGCCCAGCTCATTGCCTCAGCTAAGTATTCT
GTTATAAATGAAATCAACAAAATACGAGAAAATGAGGACCGTATCTTCGTCTATTTCATCACAAAACTGTCCCGGGTGGGAAGAGGAACA
GCCTATGTGGGCTTCCACGGAGGGCTGTGGCAGTCTGTCCACATCGATGACCTCCGGAGATCCACCCTCATGGTTTCTGATGTGACCAGG
CTGCAGCATGTCACCATCAGCCAGCTGTTCGCGCCCGGAGACTTGCCTGAGCTGGGCTTGGAACACCGGGCGGAAGACGGCCATGAGGAG
GCGATGGAGACGGAGGCCAGCACATCAGGGGAGGTGGCAGAGGTGGCAGAGGAGGCCATGGAAACAGAAAGTTCTGAGAAGGTGGGAAAG
GAAACCTCTGAACTCGGAGGCAGTGATGTGTCGATCCTGGACACCACCAGGCTGCTGAGAAGCTGTGTGCAGAGCGCCGTGGGCATGCTC
AGAGACCAGAACGAGAGCTGCACGCGCAATATGCGGAGGGTGGTGCTCCTCCTGGGCCTCTTGAATGAGGATGACGCGTGCCACGCCTCT
TTCTTGCGGGTATCCAAGATGCGCCTCAGTGTCTTTTTAAAGAAGCAAGAAGAGAGCCAGTTTCACCCTCTGGAGTGGTTGGCAAGGGAA
GCCTGCAACCAGGACGCTCTCCAGGAGGCGGGCACATTCAGGCACACCCTCTGGAAGCGGGTCCAAGGTGCTGTCACCCCTCTGCTGGCG
AGCATGATATCATTCATCGACAGAGACGGCAACCTAGAGTTACTGACCAGGCCAGATACTCCGCCCTGGGCAAGAGATCTTTGGATGTTT
ATTTTCAGTGACACGATGCTTCTGAACATTCCTCTTGTGATGAATAATGAAAGACATAAAGGTGAGATGGCCTACATCGTGGTGCAGAAC
CACATGAACCTTTCCGAGAACGCTTCCAACAACGTCCCTTTCAGCTGGAAAATCAAGGACTATCTGGAGGAGCTGTGGGTCCAGGCTCAG
TACATCACAGACGCAGAAGGACTGCCCAAGAAGTTCGTGGACATCTTTCAGCAGACTCCTCTGGGCAGGTTTCTTGCCCAGCTCCATGGA
GAGCCGCAGCAGGAACTTCTTCAGTGTTACTTGAAGGATTTCATTCTCTTGACCATGCGTGTGTCAACGGAGGAGGAATTAAAGTTTCTG
CAGATGGCTCTGTGGTCCTGCACTAGGAAACTGAAAGCGGCGTCAGAAGCGCCCGAGGAAGAGGTTTCCTTACCGTGGGTGCACCTTGCC
TACCAGCGTTTCAGAAGCCGTCTGCAGAACTTTTCCAGAATCCTGACCATCTACCCTCAGGTTCTCCACAGCCTGATGGAAGCCCGTTGG
AACCATGAGCTGGCTGGATGTGAGATGACCCTGGACGCATTTGCCGCAATGGCCTGCACGGAGATGCTGACAAGAAACACCCTGAAGCCC
AGTCCCCAGGCGTGGCTACAGTTGGTGAAGAATCTTTCCATGCCGCTGGAGCTCATCTGCTCCGATGAGCACATGCAAGGCAGCGGGAGC
CTGGCCCAGGCTGTCATCAGGGAAGTCAGAGCCCAGTGGAGTCGGATTTTCTCCACCGCACTCTTCGTGGAGCACGTGCTCCTAGGAACC
GAGAGCCGCGTCCCCGAGTTACAGGGGCTGGTGACCGAGCACGTCTTCTTACTAGACAAGTGTCTTCGAGAGAACTCTGACGTGAAGACG
CACGGGCCTTTTGAGGCCGTGATGCGCACTCTCTGTGAATGCAAGGAGACAGCCAGCAAGACCCTCAGCAGGTTTGGGATTCAGCCGTGC
TCCATCTGCCTGGGAGATGCAAAGGACCCCGTCTGTCTGCCCTGCGACCACGTGCACTGCCTGCGCTGCCTCAGGGCCTGGTTTGCCTCA
GAGCAGATGATATGCCCCTACTGTTTAACTGCCTTGCCAGACGAATTCTCTCCAGCTGTTTCCCAAGCGCACAGGGAAGCCATTGAAAAG
CATGCCCGCTTCCGGCAGATGTGCAACAGTTTCTTCGTAGACCTGGTGTCCACCATTTGCTTCAAGGACAACGCTCCGCCTGAGAAGGAA
GTGATTGAGAGCCTGCTCTCTCTCCTCTTCGTCCAAAAGGGGCGCTTAAGAGATGCTGCCCAGAGACACTGTGAACACACAAAATCTCTC
TCTCCATTCAATGATGTTGTGGATAAGACTCCTGTCATCCGCTCAGTGATACTGAAACTGCTTTTGAAGTACAGCTTTCATGATGTAAAA
GATTATATTCAGGAATATTTGACCCTGTTAAAAAAGAAAGCATTCATAACTGAAGATAAAACTGAACTGTACATGCTCTTCATCAACTGC
CTGGAGGATTCAATACTTGAGAAGACCAGTGCTTACTCCAGAAATGATGAACTGAACCACCTAGAAGAGGAAGGTCGTTTCCTTAAGGCA
TATTCTCCAGCAAGCCGGGGCCGAGAGCCTGCCAACGAGGCCTCGGTTGAATACCTGCAAGAGGTGGCCCGGATCCGCCTCTGCCTCGAC
AGAGCTGCAGATTTCCTCTCGGAGCCTGAGGGAGGCCCAGAGATGGCCAAGGAGAAGCAGTGCTACCTGCAGCAAGTCAAGCAGTTCTGT
ATCCGGGTGGAGAACGACTGGCACCGGGTGTACCTGGTGCGGAAGCTCAGCAGCCAGCGGGGGATGGAGTTCGTGCAGGGCCTCTCCAAG
CCCGGCCGCCCGCACCAGTGGGTGTTTCCCAAGGACGTTGTCAAGCAGCAGGGGCTGCGGCAGGACCACCCAGGCCAGATGGATAGGTAC
CTGGTGTACGGCGATGAATACAAGGCTCTCCGTGATGCTGTGGCCAAAGCTGTCCTCGAGTGCAAGCCACTGGGCATTAAGACTGCTCTG
AAGGCCTGCAAGACCCCCCAAAGCCAGCAGTCAGCCTACTTCCTGTTAACACTGTTTAGAGAGGTGGCTATTTTGTACAGATCCCACAAT
GCAAGCCTCCACCCCACGCCAGAGCAATGTGAAGCTGTGAGCAAATTCATTGGCGAATGCAAGATCCTTTCACCTCCTGATATCAGCCGT
TTTGCAACATCGCTCGTGGACAATTCTGTGCCATTGTTGAGGGCGGGGCCTAGTGACAGCAACCTTGATGGAACGGTGACAGAAATGGCC
ATTCATGCTGCAGCCGTCCTTCTGTGTGGACAGAATGAACTCTTGGAGCCCCTAAAGAATCTGGCCTTCTCCCCAGCCACCATGGCGCAT
GCTTTTCTTCCAACCATGCCTGAAGACTTGCTGGCTCAAGCTCGGAGGTGGAAGGGTCTGGAGCGAGTCCACTGGTACACTTGTCCCAAC
GGCCATCCTTGCTCCGTGGGAGAGTGTGGCAGGCCGATGGAACAGAGCATCTGCATTGACTGCCATGCGCCGATTGGAGGCATTGACCAC
AAACCTCGGGACGGCTTTCATCTGGTCAAAGACAAGGCAGACAGAACGCAGACCGGCCACGTGCTGGGCAACCCGCAGCGGAGAGACGTG
GTGACATGTGACCGAGGGCTGCCCCCAGTGGTCTTCCTCCTTATCCGGCTACTCACTCACTTGGCTCTGCTTCTGGGAGCGTCCCAGAGT
TCCCAGATCAGTCGCATCGAATACATTCATTCAAAGAACTTCATCCACCGGGATGTGAAGCCAGACAACTTCCTCATGGGCCTGGGGAAG
AAGGGCAACCTGGTGTACATCATCGACTTCGGGCTGGCCAAGAAGTACCGGGATGCACGCACCCACCAGCACATCCCCTATCGTGAGAAC
AAGAACCTCACGGGGACGGCGCGGTACGCCTCCATCAACACGCACCTTGGAATTGAACAATCCCGAAGAGATGACTTGGAGTCTCTGGGC
TACGTGCTAATGTACTTCAACCTGGGCTCTCTCCCCTGGCAGGGGCTGAAGGCTGCCACCAAGAGACAGAAATACGAAAGGATTAGCGAG
AAGAAAATGTCCACCCCCATCGAAGTGTTGTGTAAAGGCTACCCTTCCGAATTTGCCACATACCTGAATTTCTGCCGTTCCTTGCGTTTT
GACGACAAGCCTGACTACTCGTACCTGCGGCAGCTTTTCCGGAATCTGTTCCATCGCCAGGGCTTCTCCTATGACTACGTGTTCGACTGG
AACATGCTCAAATTTGGTGCCAGCCGGGCCGCCGATGACGCCGAGCGGGAGCGCAGGGACCGAGAGGAGCGGCTGAGACACTCGCGGAAC
CCGGCTACCCGCGGCCTCCCTTCCACAGCCTCCGGCCGCCTGCGGGGGACGCAGGAAGTGGCTCCCCCCACACCCCTCACCCCTACCTCA
CACACGGCTAACACCTCCCCCCGGCCCGTCTCCGGCATGGAGAGAGAGCGGAAAGTGAGTATGCGGCTGCACCGCGGGGCCCCCGTCAAC
ATCTCCTCGTCCGACCTCACAGGCCGACAAGATACCTCTCGCATGTCCACCTCACAGATTCCTGGTCGGGTGGCTTCCAGTGGTCTTCAG
TCTGTCGTGCACCGATGAGAACTCTCCTTATTGCTGTGAAGGGCAGACAATGCATGGCTGATCTACTCTGTTACCAATGGCTTTACTAGT
GACACGTCCCCCGGTCTAGGATCGAAATGTTAACACCGGGAGCTCTCCAGGCCACTCACCCAGCGACGCTCGTGGGGGAAACATACTAAA
CGGACAGACTCCAAGAGCTGCCACCGCTGGGGCTGCACTGCGGCCCCCCACGTGAACTCGGTTGTAACGGGGCTGGGAAGAAAAGCAGAG
AGAGAATTGCAGAGAATCAGACTCCTTTTCCAGGGCCTCAGCTCCCTCCAGTGGTGGCCGCCCTGTACTCCCTGACGATTCCACTGTAAC
TACCAATCTTCTACTTGGTTAAGACAGTTTTGTATCATTTTGCTAAAAATTATTGGCTTAAATCTGTGTAAAGAAAATCTGTCTTTTTAT
TGTTTCTTGTCTGTTTTTGCAGTCTTACAAAAAAAATGTTGACTAAGGAATTCTGAGACAGGCTGGCTTGGAGTTAGTGTATGAGGTGGA
GTCGGGCAGGGAGAAGGTGCAGGTGGATCTCAAGGGTGTGTGCTGTGTTTGTTTTGCAGTGTTTTATTGTCCGCTTTGGAGAGGAGATTT
CTCATCAAAAGTCCGTGGTGTGTGTGTGTGCCCGTGTGTGGTGGGACCTCTTCAACCTGATTTTGGCGTCTCACCCTCCCTCCTCCCGTA
ATTGACATGCCTGCTGTCAGGAACTCTTGAGGCCCTCGGAGAGCAGTTAGGGACCGCAGGCTGCCGCGGGGCAGGGGTGCAGTGGGTGTT
ACCAGGCAAAGCACTGCGCGCTTCTTCCCCAGGAGGTGGGCAGGCAGCTGAGAGCTTGGAAGCAGAGGCTTTGAGACCCTAGCAGGACAA
TTGGGAGTCCCAGGATTCAAGGTGGAAGATGCGTTTCTGGTCCCTTGGGAGAGGACTGTGAACCGAGAGGTGGTTACTGTAGTGTTTGTT
GCCTTGCTGCCTTTGCACTCAGTCCATTTTCTCAGCACTCAATGCTCCTGTGCGGATTGGCACTCCGTCTGTATGAATGCCTGTGCTTAA
AACCAGGAGCGGGGCTGTCCTTGCCACGTGCCAAGACTAGCTCAGAAAAGCCGGCAGGCCAGAAGGACCCACCCTGAGGTGCCAAGGAGC
AGGTGACTCTCCCAACCGGACCCAGAACCTTCACGGCCAGAAAGTAGAGTCTGCGCTGTGACCTTCTGTTGGGCGCGTGTCTGTTGGTCA
GAAGTGAAGCAGCGTGCGTGGGGCCGAGTCCCACCAGAAGGCAGGTGGCCTCCGTGAGCTGGTGCTGCCCCAGGCTCCATGCTGCTGTGC
CCTGAGGTTCCCAGGATGCCTTCTCGCCTCTCACTCCGCAGCACTTGGGCGGTAGCCAGTGGCCATGTGCTCCCAACCCCAATGCGCAGG
GCAGTCTGTGTTCGTGGGCACTTCGGCTGGACCCCATCACGATGGACGATGTTCCCTTTGGACTCTAGGGCTTCGAAGGTGTGCACCTTG
GTTCTCCCTTCTCCTCCCCAGAGTTCCCCGGATGCCATAACTGGCTGGCGTCCCAGAACACAGTTGTTCACCCCCCCACCAGCTGGCTGG
CCGTCTGCCTGAGCCCATGGATGCTTTCTCAATCCTAGGCTGGTTACTGTGTAAGCGTTTTGGAGTACGGGGCCTTGAGCGGGTGGGAGC
TGTGTGTTGAAGTACAGAGGGAGGTTGGGGTGGGTCAGAGCCGAGTTAAGAGATTTTCTTTGTTGCTGGACCCCTTCTTGAAGGTAGACG
TCCCCCACCCGGAGAGACGTCGCGCTGTGGCCTGAAGTGGCGCAAGCTTGCTTTGTAAATATCTGTGGTCCCGATGTAGTGCCCAGAACG
TTTGTGCGAGGCAGCTCTGCGCCCGGGTTCCAGCCCGAGCCTCGCCGGGTCGCGTCTTCGGAGTGCTTGTGACAGTCCTTGCCCAGTATC
TAGTCCCCGTCGCCCCGTGCAGGAGACGTAGGTAGGACGTCGTGTCAGCTGTGCACTGACGGCCAGTCTCCGAGCTGTGCGTTTGTATCG

>74967_74967_1_RNF213-CSNK1D_RNF213_chr17_78354787_ENST00000336301_CSNK1D_chr17_80211120_ENST00000314028_length(amino acids)=2975AA_BP=2670
MVCDGDWEHCYLPSAFSQHKVFVTPQAPLEAIQAYLAGHYRVPKQTLSAAAVFNDRLCVGIVASERAGVGKSLYVKRLHDKMKMQLNVKN
VPLKTIRLIDPQVDESRVLGALLPFLDAQYQKVPVLFHLDVTSSVQTGIWVFLFKLLILQYLMDINGKMWLRNPCHLYIVEILERRTSVP
SRSSSALRTRVPQFSFLDIFPKVTCRPPKEVIDMELSALRSDTEPGMDLWEFCSETFQRPYQYLRRFNQNQDLDTFQYQEGSVEGTPEEC
LQHFLFHCGVINPSWSELRNFARFLNYQLRDCEASLFCNPSFIGDTLRGFKKFVVTFMIFMARDFATPSLHTSDQSPGKHMVTMDGVREE
DLAPFSLRKRWESEPHPYVFFNDDHTTMTFIGFHLQPNINGSVDAISHLTGKVIKRDVMTRDLYQGLLLQRVPFNVDFDKLPRHKKLERL
CLTLGIPQATDPDKTYELTTDNMLKILAIEMRFRCGIPVIIMGETGCGKTRLIKFLSDLRRGGTNADTIKLVKVHGGTTADMIYSRVREA
ENVAFANKDQHQLDTILFFDEANTTEAISCIKEVLCDHMVDGQPLAEDSGLHIIAACNPYRKHSEEMICRLESAGLGYRVSMEETADRLG
SIPLRQLVYRVHALPPSLIPLVWDFGQLSDVAEKLYIQQIVQRLVESISLDENGTRVITEVLCASQGFMRKTEDECSFVSLRDVERCVKV
FRWFHEHSAMLLAQLNAFLSKSSVSKNHTERDPVLWSLMLAIGVCYHASLEKKDSYRKAIARFFPKPYDDSRLLLDEITRAQDLFLDGVP
LRKTIAKNLALKENVFMMVVCIELKIPLFLVGKPGSSKSLAKTIVADAMQGPAAYSDLFRSLKQVHLVSFQCSPHSTPQGIISTFRQCAR
FQQGKDLQQYVSVVVLDEVGLAEDSPKMPLKTLHPLLEDGCIEDDPAPHKKVGFVGISNWALDPAKMNRGIFVSRGSPNETELIESAKGI
CSSDILVQDRVQGYFASFAKAYETVCKRQDKEFFGLRDYYSLIKMVFAAAKASNRKPSPQDIAQAVLRNFSGKDDIQALDIFLANLPEAK
CSEEVSPMQLIKQNIFGPSQKVPGGEQEDAESRYLLVLTKNYVALQILQQTFFEGDQQPEIIFGSGFPKDQEYTQLCRNINRVKICMETG
KMVLLLNLQNLYESLYDALNQYYVHLGGQKYVDLGLGTHRVKCRVHPNFRLIVIEEKDVVYKHFPIPLINRLEKHYLDINTVLEKWQKSI
VEELCAWVEKFINVKAHHFQKRHKYSPSDVFIGYHSDACASVVLQVIERQGPRALTEELHQKVSEEAKSILLNCATPDAVVRLSAYSLGG
FAAEWLSQEYFHRQRHNSFADFLQAHLHTADLERHAIFTEITTFSRLLTSHDCEILESEVTGRAPKPTLLWLQQFDTEYSFLKEVRNCLT
NTAKCKILIFQTDFEDGIRSAQLIASAKYSVINEINKIRENEDRIFVYFITKLSRVGRGTAYVGFHGGLWQSVHIDDLRRSTLMVSDVTR
LQHVTISQLFAPGDLPELGLEHRAEDGHEEAMETEASTSGEVAEVAEEAMETESSEKVGKETSELGGSDVSILDTTRLLRSCVQSAVGML
RDQNESCTRNMRRVVLLLGLLNEDDACHASFLRVSKMRLSVFLKKQEESQFHPLEWLAREACNQDALQEAGTFRHTLWKRVQGAVTPLLA
SMISFIDRDGNLELLTRPDTPPWARDLWMFIFSDTMLLNIPLVMNNERHKGEMAYIVVQNHMNLSENASNNVPFSWKIKDYLEELWVQAQ
YITDAEGLPKKFVDIFQQTPLGRFLAQLHGEPQQELLQCYLKDFILLTMRVSTEEELKFLQMALWSCTRKLKAASEAPEEEVSLPWVHLA
YQRFRSRLQNFSRILTIYPQVLHSLMEARWNHELAGCEMTLDAFAAMACTEMLTRNTLKPSPQAWLQLVKNLSMPLELICSDEHMQGSGS
LAQAVIREVRAQWSRIFSTALFVEHVLLGTESRVPELQGLVTEHVFLLDKCLRENSDVKTHGPFEAVMRTLCECKETASKTLSRFGIQPC
SICLGDAKDPVCLPCDHVHCLRCLRAWFASEQMICPYCLTALPDEFSPAVSQAHREAIEKHARFRQMCNSFFVDLVSTICFKDNAPPEKE
VIESLLSLLFVQKGRLRDAAQRHCEHTKSLSPFNDVVDKTPVIRSVILKLLLKYSFHDVKDYIQEYLTLLKKKAFITEDKTELYMLFINC
LEDSILEKTSAYSRNDELNHLEEEGRFLKAYSPASRGREPANEASVEYLQEVARIRLCLDRAADFLSEPEGGPEMAKEKQCYLQQVKQFC
IRVENDWHRVYLVRKLSSQRGMEFVQGLSKPGRPHQWVFPKDVVKQQGLRQDHPGQMDRYLVYGDEYKALRDAVAKAVLECKPLGIKTAL
KACKTPQSQQSAYFLLTLFREVAILYRSHNASLHPTPEQCEAVSKFIGECKILSPPDISRFATSLVDNSVPLLRAGPSDSNLDGTVTEMA
IHAAAVLLCGQNELLEPLKNLAFSPATMAHAFLPTMPEDLLAQARRWKGLERVHWYTCPNGHPCSVGECGRPMEQSICIDCHAPIGGIDH
KPRDGFHLVKDKADRTQTGHVLGNPQRRDVVTCDRGLPPVVFLLIRLLTHLALLLGASQSSQISRIEYIHSKNFIHRDVKPDNFLMGLGK
KGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISE
KKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGASRAADDAERERRDREERLRHSRN
PATRGLPSTASGRLRGTQEVAPPTPLTPTSHTANTSPRPVSGMERERKVSMRLHRGAPVNISSSDLTGRQDTSRMSTSQIPGRVASSGLQ

--------------------------------------------------------------
>74967_74967_2_RNF213-CSNK1D_RNF213_chr17_78354787_ENST00000336301_CSNK1D_chr17_80211120_ENST00000392334_length(transcript)=9411nt_BP=8016nt
ATGGTCTGTGATGGGGACTGGGAGCACTGCTACCTCCCCTCTGCCTTCAGCCAGCACAAGGTCTTCGTCACCCCCCAGGCACCCCTCGAG
GCCATCCAAGCCTACCTGGCAGGTCACTACCGGGTCCCGAAGCAGACCCTGTCGGCGGCAGCCGTGTTCAATGACCGGCTGTGTGTTGGG
ATCGTGGCCTCGGAGCGAGCAGGTGTTGGAAAGTCTCTGTACGTGAAGAGGTTGCACGACAAAATGAAGATGCAGTTAAACGTGAAAAAT
GTGCCTCTGAAAACAATTCGACTGATCGACCCTCAGGTGGATGAGAGCCGAGTCCTGGGCGCCCTGCTGCCCTTCCTGGATGCGCAGTAT
CAGAAGGTCCCCGTGCTCTTTCACCTGGACGTGACCTCCTCAGTGCAGACTGGAATTTGGGTGTTTCTTTTCAAGCTCCTCATTTTACAA
TACTTAATGGATATAAATGGGAAAATGTGGCTTCGGAACCCCTGCCATTTGTATATCGTTGAAATCCTGGAAAGGAGGACGTCAGTGCCG
TCGAGGAGCTCTTCAGCGCTGCGTACACGTGTACCCCAGTTCAGTTTTCTTGACATCTTCCCAAAAGTCACCTGCAGGCCTCCCAAAGAG
GTGATAGACATGGAGCTGAGTGCCCTGAGGAGTGACACAGAGCCTGGGATGGATCTGTGGGAGTTCTGCAGCGAAACTTTCCAAAGACCT
TACCAGTATTTAAGACGATTCAATCAAAACCAAGACCTAGACACGTTTCAGTATCAAGAAGGCTCTGTCGAAGGCACCCCGGAGGAATGC
CTCCAGCATTTCCTGTTTCACTGCGGGGTAATAAACCCATCCTGGTCAGAGCTTCGGAACTTTGCTCGGTTCCTGAATTATCAGCTCAGA
GATTGTGAGGCCTCTCTCTTCTGCAATCCGAGTTTTATTGGCGACACACTGAGGGGCTTCAAGAAGTTCGTGGTGACCTTCATGATCTTT
ATGGCAAGAGATTTTGCCACACCATCACTCCACACCTCTGACCAAAGCCCGGGGAAGCACATGGTCACCATGGATGGGGTTAGGGAAGAA
GATCTAGCGCCCTTCTCCCTCCGGAAGAGGTGGGAGTCGGAGCCTCACCCATACGTTTTCTTCAATGACGACCACACAACCATGACATTC
ATCGGCTTCCATCTGCAGCCCAACATCAACGGCAGTGTCGATGCCATCAGTCACTTGACTGGGAAGGTCATCAAGAGAGACGTCATGACC
AGGGACCTGTACCAGGGCCTGCTGCTCCAGAGGGTGCCCTTCAATGTCGACTTTGATAAACTGCCCAGACACAAGAAACTTGAGAGGCTC
TGCCTGACCTTAGGGATCCCCCAGGCCACCGACCCCGACAAAACGTATGAGCTCACAACCGACAATATGCTTAAAATCCTTGCCATCGAG
ATGCGGTTCCGGTGTGGGATCCCGGTTATCATCATGGGAGAAACTGGCTGTGGGAAAACCAGGCTTATTAAATTCCTTAGCGACCTGCGG
CGTGGTGGTACCAATGCTGACACCATAAAGCTGGTCAAGGTGCACGGAGGAACAACTGCAGACATGATCTACTCCAGAGTCAGGGAGGCT
GAAAATGTGGCCTTCGCCAATAAGGACCAACATCAGTTGGACACCATCTTGTTTTTTGATGAAGCCAACACAACGGAAGCTATAAGCTGT
ATCAAAGAAGTCCTGTGTGATCATATGGTGGATGGCCAGCCTCTGGCTGAGGACTCTGGCCTGCATATTATAGCTGCCTGCAATCCATAC
CGGAAGCACTCTGAGGAGATGATCTGCCGTTTGGAGTCAGCTGGTTTGGGCTACAGGGTTAGTATGGAGGAGACGGCCGACAGGCTGGGC
TCCATTCCTCTGAGGCAGCTGGTATACCGGGTCCATGCTCTGCCCCCGAGCCTGATTCCTCTGGTGTGGGACTTTGGACAACTGAGTGAC
GTTGCTGAAAAGCTCTACATCCAGCAGATTGTCCAGAGACTGGTTGAGTCCATCAGCCTAGATGAAAACGGGACTCGCGTGATCACAGAA
GTCCTCTGCGCCTCTCAGGGTTTCATGAGGAAAACAGAAGATGAGTGCAGCTTTGTCAGCCTCAGGGACGTGGAGCGCTGTGTGAAAGTT
TTCAGGTGGTTCCACGAGCACAGCGCGATGCTCTTAGCGCAGCTGAATGCCTTTCTCTCCAAGTCCAGCGTCAGCAAAAATCACACCGAG
AGAGATCCCGTCCTCTGGTCGTTGATGCTGGCCATCGGGGTGTGTTACCATGCCTCTTTAGAAAAGAAAGACTCATATCGGAAAGCCATC
GCCAGGTTCTTTCCGAAACCGTATGACGACAGCAGGCTGCTTCTGGATGAAATAACACGGGCACAGGATCTTTTTCTGGACGGCGTACCT
CTGAGGAAAACCATCGCCAAGAACTTGGCCTTGAAGGAGAACGTCTTCATGATGGTCGTCTGCATCGAGCTGAAGATTCCCCTCTTCCTG
GTGGGGAAGCCCGGCAGCTCCAAGTCTCTCGCCAAGACCATCGTGGCAGACGCCATGCAGGGCCCGGCTGCCTACTCAGATCTCTTCCGC
AGCCTGAAGCAGGTCCACCTGGTGTCCTTCCAGTGCAGCCCGCACTCCACCCCACAGGGCATCATCAGCACCTTCCGGCAGTGCGCCCGC
TTTCAGCAGGGGAAGGACCTGCAGCAGTACGTCTCTGTGGTGGTGTTAGATGAGGTGGGGCTGGCGGAAGACTCACCCAAAATGCCCCTG
AAGACTCTGCACCCGCTGCTGGAAGACGGATGCATTGAAGACGATCCCGCCCCCCACAAAAAGGTCGGCTTCGTGGGCATCTCCAACTGG
GCCCTTGACCCTGCCAAGATGAACCGGGGCATTTTTGTGTCACGTGGCAGCCCCAACGAGACAGAGCTCATAGAGAGCGCCAAGGGCATC
TGCTCCTCAGACATCCTCGTCCAGGACCGAGTCCAAGGGTACTTTGCGTCCTTTGCCAAAGCCTACGAAACGGTGTGTAAGCGCCAGGAC
AAGGAATTCTTCGGGCTTCGTGACTACTACAGCCTCATCAAAATGGTCTTTGCTGCAGCAAAGGCTTCAAATAGAAAGCCTTCCCCGCAA
GACATTGCACAGGCTGTCCTTAGGAACTTCAGTGGCAAGGATGACATCCAAGCTTTGGACATCTTTCTGGCCAATTTGCCCGAGGCCAAG
TGCTCAGAGGAAGTCAGCCCCATGCAGCTGATCAAACAGAACATCTTTGGGCCTTCTCAGAAGGTGCCGGGTGGAGAGCAGGAAGATGCT
GAGTCCCGCTACTTACTCGTGCTGACCAAAAACTACGTGGCACTGCAGATCCTGCAGCAGACATTCTTCGAGGGGGACCAGCAGCCGGAG
ATTATTTTTGGTTCTGGTTTCCCCAAGGACCAAGAGTACACCCAGCTCTGCAGAAACATCAATCGTGTGAAGATCTGCATGGAAACAGGC
AAGATGGTGTTGCTTCTCAACCTGCAGAACCTCTACGAGAGCCTCTACGACGCACTCAACCAGTACTACGTCCACCTCGGCGGCCAGAAG
TACGTGGACCTCGGTCTGGGGACCCACCGCGTCAAATGTCGGGTTCACCCCAACTTCCGCCTGATTGTCATTGAAGAGAAAGACGTCGTG
TACAAACACTTTCCCATCCCCCTCATTAACCGGCTGGAGAAGCACTATCTGGATATCAACACGGTGCTGGAGAAATGGCAGAAGAGCATC
GTGGAGGAGCTCTGTGCGTGGGTGGAGAAGTTCATCAATGTCAAAGCACATCATTTCCAGAAGAGGCACAAATACAGCCCCTCTGACGTC
TTCATCGGCTACCACTCGGACGCCTGCGCGTCTGTGGTGCTGCAGGTCATAGAGAGGCAGGGTCCCCGGGCCTTGACGGAGGAACTTCAC
CAGAAGGTGTCTGAGGAGGCCAAATCGATCCTGCTGAACTGCGCTACGCCCGATGCCGTGGTCCGGCTGAGCGCCTACTCGCTGGGCGGG
TTCGCAGCGGAGTGGCTGTCGCAGGAGTACTTTCACAGACAGAGGCACAACTCCTTTGCAGATTTCCTTCAGGCACACCTGCACACGGCA
GACCTGGAGCGCCACGCCATCTTCACAGAGATCACCACTTTCTCCAGGCTGCTAACAAGTCACGACTGTGAAATTTTAGAATCAGAGGTC
ACAGGCAGGGCTCCGAAACCCACACTCCTGTGGCTGCAGCAGTTTGACACCGAGTACTCATTCCTCAAAGAAGTCCGAAACTGTTTAACG
AATACAGCCAAATGTAAAATCCTCATTTTTCAGACAGATTTTGAAGATGGAATCCGTAGCGCCCAGCTCATTGCCTCAGCTAAGTATTCT
GTTATAAATGAAATCAACAAAATACGAGAAAATGAGGACCGTATCTTCGTCTATTTCATCACAAAACTGTCCCGGGTGGGAAGAGGAACA
GCCTATGTGGGCTTCCACGGAGGGCTGTGGCAGTCTGTCCACATCGATGACCTCCGGAGATCCACCCTCATGGTTTCTGATGTGACCAGG
CTGCAGCATGTCACCATCAGCCAGCTGTTCGCGCCCGGAGACTTGCCTGAGCTGGGCTTGGAACACCGGGCGGAAGACGGCCATGAGGAG
GCGATGGAGACGGAGGCCAGCACATCAGGGGAGGTGGCAGAGGTGGCAGAGGAGGCCATGGAAACAGAAAGTTCTGAGAAGGTGGGAAAG
GAAACCTCTGAACTCGGAGGCAGTGATGTGTCGATCCTGGACACCACCAGGCTGCTGAGAAGCTGTGTGCAGAGCGCCGTGGGCATGCTC
AGAGACCAGAACGAGAGCTGCACGCGCAATATGCGGAGGGTGGTGCTCCTCCTGGGCCTCTTGAATGAGGATGACGCGTGCCACGCCTCT
TTCTTGCGGGTATCCAAGATGCGCCTCAGTGTCTTTTTAAAGAAGCAAGAAGAGAGCCAGTTTCACCCTCTGGAGTGGTTGGCAAGGGAA
GCCTGCAACCAGGACGCTCTCCAGGAGGCGGGCACATTCAGGCACACCCTCTGGAAGCGGGTCCAAGGTGCTGTCACCCCTCTGCTGGCG
AGCATGATATCATTCATCGACAGAGACGGCAACCTAGAGTTACTGACCAGGCCAGATACTCCGCCCTGGGCAAGAGATCTTTGGATGTTT
ATTTTCAGTGACACGATGCTTCTGAACATTCCTCTTGTGATGAATAATGAAAGACATAAAGGTGAGATGGCCTACATCGTGGTGCAGAAC
CACATGAACCTTTCCGAGAACGCTTCCAACAACGTCCCTTTCAGCTGGAAAATCAAGGACTATCTGGAGGAGCTGTGGGTCCAGGCTCAG
TACATCACAGACGCAGAAGGACTGCCCAAGAAGTTCGTGGACATCTTTCAGCAGACTCCTCTGGGCAGGTTTCTTGCCCAGCTCCATGGA
GAGCCGCAGCAGGAACTTCTTCAGTGTTACTTGAAGGATTTCATTCTCTTGACCATGCGTGTGTCAACGGAGGAGGAATTAAAGTTTCTG
CAGATGGCTCTGTGGTCCTGCACTAGGAAACTGAAAGCGGCGTCAGAAGCGCCCGAGGAAGAGGTTTCCTTACCGTGGGTGCACCTTGCC
TACCAGCGTTTCAGAAGCCGTCTGCAGAACTTTTCCAGAATCCTGACCATCTACCCTCAGGTTCTCCACAGCCTGATGGAAGCCCGTTGG
AACCATGAGCTGGCTGGATGTGAGATGACCCTGGACGCATTTGCCGCAATGGCCTGCACGGAGATGCTGACAAGAAACACCCTGAAGCCC
AGTCCCCAGGCGTGGCTACAGTTGGTGAAGAATCTTTCCATGCCGCTGGAGCTCATCTGCTCCGATGAGCACATGCAAGGCAGCGGGAGC
CTGGCCCAGGCTGTCATCAGGGAAGTCAGAGCCCAGTGGAGTCGGATTTTCTCCACCGCACTCTTCGTGGAGCACGTGCTCCTAGGAACC
GAGAGCCGCGTCCCCGAGTTACAGGGGCTGGTGACCGAGCACGTCTTCTTACTAGACAAGTGTCTTCGAGAGAACTCTGACGTGAAGACG
CACGGGCCTTTTGAGGCCGTGATGCGCACTCTCTGTGAATGCAAGGAGACAGCCAGCAAGACCCTCAGCAGGTTTGGGATTCAGCCGTGC
TCCATCTGCCTGGGAGATGCAAAGGACCCCGTCTGTCTGCCCTGCGACCACGTGCACTGCCTGCGCTGCCTCAGGGCCTGGTTTGCCTCA
GAGCAGATGATATGCCCCTACTGTTTAACTGCCTTGCCAGACGAATTCTCTCCAGCTGTTTCCCAAGCGCACAGGGAAGCCATTGAAAAG
CATGCCCGCTTCCGGCAGATGTGCAACAGTTTCTTCGTAGACCTGGTGTCCACCATTTGCTTCAAGGACAACGCTCCGCCTGAGAAGGAA
GTGATTGAGAGCCTGCTCTCTCTCCTCTTCGTCCAAAAGGGGCGCTTAAGAGATGCTGCCCAGAGACACTGTGAACACACAAAATCTCTC
TCTCCATTCAATGATGTTGTGGATAAGACTCCTGTCATCCGCTCAGTGATACTGAAACTGCTTTTGAAGTACAGCTTTCATGATGTAAAA
GATTATATTCAGGAATATTTGACCCTGTTAAAAAAGAAAGCATTCATAACTGAAGATAAAACTGAACTGTACATGCTCTTCATCAACTGC
CTGGAGGATTCAATACTTGAGAAGACCAGTGCTTACTCCAGAAATGATGAACTGAACCACCTAGAAGAGGAAGGTCGTTTCCTTAAGGCA
TATTCTCCAGCAAGCCGGGGCCGAGAGCCTGCCAACGAGGCCTCGGTTGAATACCTGCAAGAGGTGGCCCGGATCCGCCTCTGCCTCGAC
AGAGCTGCAGATTTCCTCTCGGAGCCTGAGGGAGGCCCAGAGATGGCCAAGGAGAAGCAGTGCTACCTGCAGCAAGTCAAGCAGTTCTGT
ATCCGGGTGGAGAACGACTGGCACCGGGTGTACCTGGTGCGGAAGCTCAGCAGCCAGCGGGGGATGGAGTTCGTGCAGGGCCTCTCCAAG
CCCGGCCGCCCGCACCAGTGGGTGTTTCCCAAGGACGTTGTCAAGCAGCAGGGGCTGCGGCAGGACCACCCAGGCCAGATGGATAGGTAC
CTGGTGTACGGCGATGAATACAAGGCTCTCCGTGATGCTGTGGCCAAAGCTGTCCTCGAGTGCAAGCCACTGGGCATTAAGACTGCTCTG
AAGGCCTGCAAGACCCCCCAAAGCCAGCAGTCAGCCTACTTCCTGTTAACACTGTTTAGAGAGGTGGCTATTTTGTACAGATCCCACAAT
GCAAGCCTCCACCCCACGCCAGAGCAATGTGAAGCTGTGAGCAAATTCATTGGCGAATGCAAGATCCTTTCACCTCCTGATATCAGCCGT
TTTGCAACATCGCTCGTGGACAATTCTGTGCCATTGTTGAGGGCGGGGCCTAGTGACAGCAACCTTGATGGAACGGTGACAGAAATGGCC
ATTCATGCTGCAGCCGTCCTTCTGTGTGGACAGAATGAACTCTTGGAGCCCCTAAAGAATCTGGCCTTCTCCCCAGCCACCATGGCGCAT
GCTTTTCTTCCAACCATGCCTGAAGACTTGCTGGCTCAAGCTCGGAGGTGGAAGGGTCTGGAGCGAGTCCACTGGTACACTTGTCCCAAC
GGCCATCCTTGCTCCGTGGGAGAGTGTGGCAGGCCGATGGAACAGAGCATCTGCATTGACTGCCATGCGCCGATTGGAGGCATTGACCAC
AAACCTCGGGACGGCTTTCATCTGGTCAAAGACAAGGCAGACAGAACGCAGACCGGCCACGTGCTGGGCAACCCGCAGCGGAGAGACGTG
GTGACATGTGACCGAGGGCTGCCCCCAGTGGTCTTCCTCCTTATCCGGCTACTCACTCACTTGGCTCTGCTTCTGGGAGCGTCCCAGAGT
TCCCAGATCAGTCGCATCGAATACATTCATTCAAAGAACTTCATCCACCGGGATGTGAAGCCAGACAACTTCCTCATGGGCCTGGGGAAG
AAGGGCAACCTGGTGTACATCATCGACTTCGGGCTGGCCAAGAAGTACCGGGATGCACGCACCCACCAGCACATCCCCTATCGTGAGAAC
AAGAACCTCACGGGGACGGCGCGGTACGCCTCCATCAACACGCACCTTGGAATTGAACAATCCCGAAGAGATGACTTGGAGTCTCTGGGC
TACGTGCTAATGTACTTCAACCTGGGCTCTCTCCCCTGGCAGGGGCTGAAGGCTGCCACCAAGAGACAGAAATACGAAAGGATTAGCGAG
AAGAAAATGTCCACCCCCATCGAAGTGTTGTGTAAAGGCTACCCTTCCGAATTTGCCACATACCTGAATTTCTGCCGTTCCTTGCGTTTT
GACGACAAGCCTGACTACTCGTACCTGCGGCAGCTTTTCCGGAATCTGTTCCATCGCCAGGGCTTCTCCTATGACTACGTGTTCGACTGG
AACATGCTCAAATTTGGTGCCAGCCGGGCCGCCGATGACGCCGAGCGGGAGCGCAGGGACCGAGAGGAGCGGCTGAGACACTCGCGGAAC
CCGGCTACCCGCGGCCTCCCTTCCACAGCCTCCGGCCGCCTGCGGGGGACGCAGGAAGTGGCTCCCCCCACACCCCTCACCCCTACCTCA
CACACGGCTAACACCTCCCCCCGGCCCGTCTCCGGCATGGAGAGAGAGCGGAAAGTGAGTATGCGGCTGCACCGCGGGGCCCCCGTCAAC
ATCTCCTCGTCCGACCTCACAGGCCGACAAGATACCTCTCGCATGTCCACCTCACAGAATAGCATTCCTTTCGAACACCACGGCAAGTAG
CTGCTCGTCTCCCATCGGAAGGCAGCACTGGATTCCTGGTCGGGTGGCTTCCAGTGGTCTTCAGTCTGTCGTGCACCGATGAGAACTCTC
CTTATTGCTGTGAAGGGCAGACAATGCATGGCTGATCTACTCTGTTACCAATGGCTTTACTAGTGACACGTCCCCCGGTCTAGGATCGAA
ATGTTAACACCGGGAGCTCTCCAGGCCACTCACCCAGCGACGCTCGTGGGGGAAACATACTAAACGGACAGACTCCAAGAGCTGCCACCG
CTGGGGCTGCACTGCGGCCCCCCACGTGAACTCGGTTGTAACGGGGCTGGGAAGAAAAGCAGAGAGAGAATTGCAGAGAATCAGACTCCT
TTTCCAGGGCCTCAGCTCCCTCCAGTGGTGGCCGCCCTGTACTCCCTGACGATTCCACTGTAACTACCAATCTTCTACTTGGTTAAGACA

>74967_74967_2_RNF213-CSNK1D_RNF213_chr17_78354787_ENST00000336301_CSNK1D_chr17_80211120_ENST00000392334_length(amino acids)=2969AA_BP=2670
MVCDGDWEHCYLPSAFSQHKVFVTPQAPLEAIQAYLAGHYRVPKQTLSAAAVFNDRLCVGIVASERAGVGKSLYVKRLHDKMKMQLNVKN
VPLKTIRLIDPQVDESRVLGALLPFLDAQYQKVPVLFHLDVTSSVQTGIWVFLFKLLILQYLMDINGKMWLRNPCHLYIVEILERRTSVP
SRSSSALRTRVPQFSFLDIFPKVTCRPPKEVIDMELSALRSDTEPGMDLWEFCSETFQRPYQYLRRFNQNQDLDTFQYQEGSVEGTPEEC
LQHFLFHCGVINPSWSELRNFARFLNYQLRDCEASLFCNPSFIGDTLRGFKKFVVTFMIFMARDFATPSLHTSDQSPGKHMVTMDGVREE
DLAPFSLRKRWESEPHPYVFFNDDHTTMTFIGFHLQPNINGSVDAISHLTGKVIKRDVMTRDLYQGLLLQRVPFNVDFDKLPRHKKLERL
CLTLGIPQATDPDKTYELTTDNMLKILAIEMRFRCGIPVIIMGETGCGKTRLIKFLSDLRRGGTNADTIKLVKVHGGTTADMIYSRVREA
ENVAFANKDQHQLDTILFFDEANTTEAISCIKEVLCDHMVDGQPLAEDSGLHIIAACNPYRKHSEEMICRLESAGLGYRVSMEETADRLG
SIPLRQLVYRVHALPPSLIPLVWDFGQLSDVAEKLYIQQIVQRLVESISLDENGTRVITEVLCASQGFMRKTEDECSFVSLRDVERCVKV
FRWFHEHSAMLLAQLNAFLSKSSVSKNHTERDPVLWSLMLAIGVCYHASLEKKDSYRKAIARFFPKPYDDSRLLLDEITRAQDLFLDGVP
LRKTIAKNLALKENVFMMVVCIELKIPLFLVGKPGSSKSLAKTIVADAMQGPAAYSDLFRSLKQVHLVSFQCSPHSTPQGIISTFRQCAR
FQQGKDLQQYVSVVVLDEVGLAEDSPKMPLKTLHPLLEDGCIEDDPAPHKKVGFVGISNWALDPAKMNRGIFVSRGSPNETELIESAKGI
CSSDILVQDRVQGYFASFAKAYETVCKRQDKEFFGLRDYYSLIKMVFAAAKASNRKPSPQDIAQAVLRNFSGKDDIQALDIFLANLPEAK
CSEEVSPMQLIKQNIFGPSQKVPGGEQEDAESRYLLVLTKNYVALQILQQTFFEGDQQPEIIFGSGFPKDQEYTQLCRNINRVKICMETG
KMVLLLNLQNLYESLYDALNQYYVHLGGQKYVDLGLGTHRVKCRVHPNFRLIVIEEKDVVYKHFPIPLINRLEKHYLDINTVLEKWQKSI
VEELCAWVEKFINVKAHHFQKRHKYSPSDVFIGYHSDACASVVLQVIERQGPRALTEELHQKVSEEAKSILLNCATPDAVVRLSAYSLGG
FAAEWLSQEYFHRQRHNSFADFLQAHLHTADLERHAIFTEITTFSRLLTSHDCEILESEVTGRAPKPTLLWLQQFDTEYSFLKEVRNCLT
NTAKCKILIFQTDFEDGIRSAQLIASAKYSVINEINKIRENEDRIFVYFITKLSRVGRGTAYVGFHGGLWQSVHIDDLRRSTLMVSDVTR
LQHVTISQLFAPGDLPELGLEHRAEDGHEEAMETEASTSGEVAEVAEEAMETESSEKVGKETSELGGSDVSILDTTRLLRSCVQSAVGML
RDQNESCTRNMRRVVLLLGLLNEDDACHASFLRVSKMRLSVFLKKQEESQFHPLEWLAREACNQDALQEAGTFRHTLWKRVQGAVTPLLA
SMISFIDRDGNLELLTRPDTPPWARDLWMFIFSDTMLLNIPLVMNNERHKGEMAYIVVQNHMNLSENASNNVPFSWKIKDYLEELWVQAQ
YITDAEGLPKKFVDIFQQTPLGRFLAQLHGEPQQELLQCYLKDFILLTMRVSTEEELKFLQMALWSCTRKLKAASEAPEEEVSLPWVHLA
YQRFRSRLQNFSRILTIYPQVLHSLMEARWNHELAGCEMTLDAFAAMACTEMLTRNTLKPSPQAWLQLVKNLSMPLELICSDEHMQGSGS
LAQAVIREVRAQWSRIFSTALFVEHVLLGTESRVPELQGLVTEHVFLLDKCLRENSDVKTHGPFEAVMRTLCECKETASKTLSRFGIQPC
SICLGDAKDPVCLPCDHVHCLRCLRAWFASEQMICPYCLTALPDEFSPAVSQAHREAIEKHARFRQMCNSFFVDLVSTICFKDNAPPEKE
VIESLLSLLFVQKGRLRDAAQRHCEHTKSLSPFNDVVDKTPVIRSVILKLLLKYSFHDVKDYIQEYLTLLKKKAFITEDKTELYMLFINC
LEDSILEKTSAYSRNDELNHLEEEGRFLKAYSPASRGREPANEASVEYLQEVARIRLCLDRAADFLSEPEGGPEMAKEKQCYLQQVKQFC
IRVENDWHRVYLVRKLSSQRGMEFVQGLSKPGRPHQWVFPKDVVKQQGLRQDHPGQMDRYLVYGDEYKALRDAVAKAVLECKPLGIKTAL
KACKTPQSQQSAYFLLTLFREVAILYRSHNASLHPTPEQCEAVSKFIGECKILSPPDISRFATSLVDNSVPLLRAGPSDSNLDGTVTEMA
IHAAAVLLCGQNELLEPLKNLAFSPATMAHAFLPTMPEDLLAQARRWKGLERVHWYTCPNGHPCSVGECGRPMEQSICIDCHAPIGGIDH
KPRDGFHLVKDKADRTQTGHVLGNPQRRDVVTCDRGLPPVVFLLIRLLTHLALLLGASQSSQISRIEYIHSKNFIHRDVKPDNFLMGLGK
KGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISE
KKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGASRAADDAERERRDREERLRHSRN

--------------------------------------------------------------
>74967_74967_3_RNF213-CSNK1D_RNF213_chr17_78354787_ENST00000336301_CSNK1D_chr17_80211120_ENST00000398519_length(transcript)=9213nt_BP=8016nt
ATGGTCTGTGATGGGGACTGGGAGCACTGCTACCTCCCCTCTGCCTTCAGCCAGCACAAGGTCTTCGTCACCCCCCAGGCACCCCTCGAG
GCCATCCAAGCCTACCTGGCAGGTCACTACCGGGTCCCGAAGCAGACCCTGTCGGCGGCAGCCGTGTTCAATGACCGGCTGTGTGTTGGG
ATCGTGGCCTCGGAGCGAGCAGGTGTTGGAAAGTCTCTGTACGTGAAGAGGTTGCACGACAAAATGAAGATGCAGTTAAACGTGAAAAAT
GTGCCTCTGAAAACAATTCGACTGATCGACCCTCAGGTGGATGAGAGCCGAGTCCTGGGCGCCCTGCTGCCCTTCCTGGATGCGCAGTAT
CAGAAGGTCCCCGTGCTCTTTCACCTGGACGTGACCTCCTCAGTGCAGACTGGAATTTGGGTGTTTCTTTTCAAGCTCCTCATTTTACAA
TACTTAATGGATATAAATGGGAAAATGTGGCTTCGGAACCCCTGCCATTTGTATATCGTTGAAATCCTGGAAAGGAGGACGTCAGTGCCG
TCGAGGAGCTCTTCAGCGCTGCGTACACGTGTACCCCAGTTCAGTTTTCTTGACATCTTCCCAAAAGTCACCTGCAGGCCTCCCAAAGAG
GTGATAGACATGGAGCTGAGTGCCCTGAGGAGTGACACAGAGCCTGGGATGGATCTGTGGGAGTTCTGCAGCGAAACTTTCCAAAGACCT
TACCAGTATTTAAGACGATTCAATCAAAACCAAGACCTAGACACGTTTCAGTATCAAGAAGGCTCTGTCGAAGGCACCCCGGAGGAATGC
CTCCAGCATTTCCTGTTTCACTGCGGGGTAATAAACCCATCCTGGTCAGAGCTTCGGAACTTTGCTCGGTTCCTGAATTATCAGCTCAGA
GATTGTGAGGCCTCTCTCTTCTGCAATCCGAGTTTTATTGGCGACACACTGAGGGGCTTCAAGAAGTTCGTGGTGACCTTCATGATCTTT
ATGGCAAGAGATTTTGCCACACCATCACTCCACACCTCTGACCAAAGCCCGGGGAAGCACATGGTCACCATGGATGGGGTTAGGGAAGAA
GATCTAGCGCCCTTCTCCCTCCGGAAGAGGTGGGAGTCGGAGCCTCACCCATACGTTTTCTTCAATGACGACCACACAACCATGACATTC
ATCGGCTTCCATCTGCAGCCCAACATCAACGGCAGTGTCGATGCCATCAGTCACTTGACTGGGAAGGTCATCAAGAGAGACGTCATGACC
AGGGACCTGTACCAGGGCCTGCTGCTCCAGAGGGTGCCCTTCAATGTCGACTTTGATAAACTGCCCAGACACAAGAAACTTGAGAGGCTC
TGCCTGACCTTAGGGATCCCCCAGGCCACCGACCCCGACAAAACGTATGAGCTCACAACCGACAATATGCTTAAAATCCTTGCCATCGAG
ATGCGGTTCCGGTGTGGGATCCCGGTTATCATCATGGGAGAAACTGGCTGTGGGAAAACCAGGCTTATTAAATTCCTTAGCGACCTGCGG
CGTGGTGGTACCAATGCTGACACCATAAAGCTGGTCAAGGTGCACGGAGGAACAACTGCAGACATGATCTACTCCAGAGTCAGGGAGGCT
GAAAATGTGGCCTTCGCCAATAAGGACCAACATCAGTTGGACACCATCTTGTTTTTTGATGAAGCCAACACAACGGAAGCTATAAGCTGT
ATCAAAGAAGTCCTGTGTGATCATATGGTGGATGGCCAGCCTCTGGCTGAGGACTCTGGCCTGCATATTATAGCTGCCTGCAATCCATAC
CGGAAGCACTCTGAGGAGATGATCTGCCGTTTGGAGTCAGCTGGTTTGGGCTACAGGGTTAGTATGGAGGAGACGGCCGACAGGCTGGGC
TCCATTCCTCTGAGGCAGCTGGTATACCGGGTCCATGCTCTGCCCCCGAGCCTGATTCCTCTGGTGTGGGACTTTGGACAACTGAGTGAC
GTTGCTGAAAAGCTCTACATCCAGCAGATTGTCCAGAGACTGGTTGAGTCCATCAGCCTAGATGAAAACGGGACTCGCGTGATCACAGAA
GTCCTCTGCGCCTCTCAGGGTTTCATGAGGAAAACAGAAGATGAGTGCAGCTTTGTCAGCCTCAGGGACGTGGAGCGCTGTGTGAAAGTT
TTCAGGTGGTTCCACGAGCACAGCGCGATGCTCTTAGCGCAGCTGAATGCCTTTCTCTCCAAGTCCAGCGTCAGCAAAAATCACACCGAG
AGAGATCCCGTCCTCTGGTCGTTGATGCTGGCCATCGGGGTGTGTTACCATGCCTCTTTAGAAAAGAAAGACTCATATCGGAAAGCCATC
GCCAGGTTCTTTCCGAAACCGTATGACGACAGCAGGCTGCTTCTGGATGAAATAACACGGGCACAGGATCTTTTTCTGGACGGCGTACCT
CTGAGGAAAACCATCGCCAAGAACTTGGCCTTGAAGGAGAACGTCTTCATGATGGTCGTCTGCATCGAGCTGAAGATTCCCCTCTTCCTG
GTGGGGAAGCCCGGCAGCTCCAAGTCTCTCGCCAAGACCATCGTGGCAGACGCCATGCAGGGCCCGGCTGCCTACTCAGATCTCTTCCGC
AGCCTGAAGCAGGTCCACCTGGTGTCCTTCCAGTGCAGCCCGCACTCCACCCCACAGGGCATCATCAGCACCTTCCGGCAGTGCGCCCGC
TTTCAGCAGGGGAAGGACCTGCAGCAGTACGTCTCTGTGGTGGTGTTAGATGAGGTGGGGCTGGCGGAAGACTCACCCAAAATGCCCCTG
AAGACTCTGCACCCGCTGCTGGAAGACGGATGCATTGAAGACGATCCCGCCCCCCACAAAAAGGTCGGCTTCGTGGGCATCTCCAACTGG
GCCCTTGACCCTGCCAAGATGAACCGGGGCATTTTTGTGTCACGTGGCAGCCCCAACGAGACAGAGCTCATAGAGAGCGCCAAGGGCATC
TGCTCCTCAGACATCCTCGTCCAGGACCGAGTCCAAGGGTACTTTGCGTCCTTTGCCAAAGCCTACGAAACGGTGTGTAAGCGCCAGGAC
AAGGAATTCTTCGGGCTTCGTGACTACTACAGCCTCATCAAAATGGTCTTTGCTGCAGCAAAGGCTTCAAATAGAAAGCCTTCCCCGCAA
GACATTGCACAGGCTGTCCTTAGGAACTTCAGTGGCAAGGATGACATCCAAGCTTTGGACATCTTTCTGGCCAATTTGCCCGAGGCCAAG
TGCTCAGAGGAAGTCAGCCCCATGCAGCTGATCAAACAGAACATCTTTGGGCCTTCTCAGAAGGTGCCGGGTGGAGAGCAGGAAGATGCT
GAGTCCCGCTACTTACTCGTGCTGACCAAAAACTACGTGGCACTGCAGATCCTGCAGCAGACATTCTTCGAGGGGGACCAGCAGCCGGAG
ATTATTTTTGGTTCTGGTTTCCCCAAGGACCAAGAGTACACCCAGCTCTGCAGAAACATCAATCGTGTGAAGATCTGCATGGAAACAGGC
AAGATGGTGTTGCTTCTCAACCTGCAGAACCTCTACGAGAGCCTCTACGACGCACTCAACCAGTACTACGTCCACCTCGGCGGCCAGAAG
TACGTGGACCTCGGTCTGGGGACCCACCGCGTCAAATGTCGGGTTCACCCCAACTTCCGCCTGATTGTCATTGAAGAGAAAGACGTCGTG
TACAAACACTTTCCCATCCCCCTCATTAACCGGCTGGAGAAGCACTATCTGGATATCAACACGGTGCTGGAGAAATGGCAGAAGAGCATC
GTGGAGGAGCTCTGTGCGTGGGTGGAGAAGTTCATCAATGTCAAAGCACATCATTTCCAGAAGAGGCACAAATACAGCCCCTCTGACGTC
TTCATCGGCTACCACTCGGACGCCTGCGCGTCTGTGGTGCTGCAGGTCATAGAGAGGCAGGGTCCCCGGGCCTTGACGGAGGAACTTCAC
CAGAAGGTGTCTGAGGAGGCCAAATCGATCCTGCTGAACTGCGCTACGCCCGATGCCGTGGTCCGGCTGAGCGCCTACTCGCTGGGCGGG
TTCGCAGCGGAGTGGCTGTCGCAGGAGTACTTTCACAGACAGAGGCACAACTCCTTTGCAGATTTCCTTCAGGCACACCTGCACACGGCA
GACCTGGAGCGCCACGCCATCTTCACAGAGATCACCACTTTCTCCAGGCTGCTAACAAGTCACGACTGTGAAATTTTAGAATCAGAGGTC
ACAGGCAGGGCTCCGAAACCCACACTCCTGTGGCTGCAGCAGTTTGACACCGAGTACTCATTCCTCAAAGAAGTCCGAAACTGTTTAACG
AATACAGCCAAATGTAAAATCCTCATTTTTCAGACAGATTTTGAAGATGGAATCCGTAGCGCCCAGCTCATTGCCTCAGCTAAGTATTCT
GTTATAAATGAAATCAACAAAATACGAGAAAATGAGGACCGTATCTTCGTCTATTTCATCACAAAACTGTCCCGGGTGGGAAGAGGAACA
GCCTATGTGGGCTTCCACGGAGGGCTGTGGCAGTCTGTCCACATCGATGACCTCCGGAGATCCACCCTCATGGTTTCTGATGTGACCAGG
CTGCAGCATGTCACCATCAGCCAGCTGTTCGCGCCCGGAGACTTGCCTGAGCTGGGCTTGGAACACCGGGCGGAAGACGGCCATGAGGAG
GCGATGGAGACGGAGGCCAGCACATCAGGGGAGGTGGCAGAGGTGGCAGAGGAGGCCATGGAAACAGAAAGTTCTGAGAAGGTGGGAAAG
GAAACCTCTGAACTCGGAGGCAGTGATGTGTCGATCCTGGACACCACCAGGCTGCTGAGAAGCTGTGTGCAGAGCGCCGTGGGCATGCTC
AGAGACCAGAACGAGAGCTGCACGCGCAATATGCGGAGGGTGGTGCTCCTCCTGGGCCTCTTGAATGAGGATGACGCGTGCCACGCCTCT
TTCTTGCGGGTATCCAAGATGCGCCTCAGTGTCTTTTTAAAGAAGCAAGAAGAGAGCCAGTTTCACCCTCTGGAGTGGTTGGCAAGGGAA
GCCTGCAACCAGGACGCTCTCCAGGAGGCGGGCACATTCAGGCACACCCTCTGGAAGCGGGTCCAAGGTGCTGTCACCCCTCTGCTGGCG
AGCATGATATCATTCATCGACAGAGACGGCAACCTAGAGTTACTGACCAGGCCAGATACTCCGCCCTGGGCAAGAGATCTTTGGATGTTT
ATTTTCAGTGACACGATGCTTCTGAACATTCCTCTTGTGATGAATAATGAAAGACATAAAGGTGAGATGGCCTACATCGTGGTGCAGAAC
CACATGAACCTTTCCGAGAACGCTTCCAACAACGTCCCTTTCAGCTGGAAAATCAAGGACTATCTGGAGGAGCTGTGGGTCCAGGCTCAG
TACATCACAGACGCAGAAGGACTGCCCAAGAAGTTCGTGGACATCTTTCAGCAGACTCCTCTGGGCAGGTTTCTTGCCCAGCTCCATGGA
GAGCCGCAGCAGGAACTTCTTCAGTGTTACTTGAAGGATTTCATTCTCTTGACCATGCGTGTGTCAACGGAGGAGGAATTAAAGTTTCTG
CAGATGGCTCTGTGGTCCTGCACTAGGAAACTGAAAGCGGCGTCAGAAGCGCCCGAGGAAGAGGTTTCCTTACCGTGGGTGCACCTTGCC
TACCAGCGTTTCAGAAGCCGTCTGCAGAACTTTTCCAGAATCCTGACCATCTACCCTCAGGTTCTCCACAGCCTGATGGAAGCCCGTTGG
AACCATGAGCTGGCTGGATGTGAGATGACCCTGGACGCATTTGCCGCAATGGCCTGCACGGAGATGCTGACAAGAAACACCCTGAAGCCC
AGTCCCCAGGCGTGGCTACAGTTGGTGAAGAATCTTTCCATGCCGCTGGAGCTCATCTGCTCCGATGAGCACATGCAAGGCAGCGGGAGC
CTGGCCCAGGCTGTCATCAGGGAAGTCAGAGCCCAGTGGAGTCGGATTTTCTCCACCGCACTCTTCGTGGAGCACGTGCTCCTAGGAACC
GAGAGCCGCGTCCCCGAGTTACAGGGGCTGGTGACCGAGCACGTCTTCTTACTAGACAAGTGTCTTCGAGAGAACTCTGACGTGAAGACG
CACGGGCCTTTTGAGGCCGTGATGCGCACTCTCTGTGAATGCAAGGAGACAGCCAGCAAGACCCTCAGCAGGTTTGGGATTCAGCCGTGC
TCCATCTGCCTGGGAGATGCAAAGGACCCCGTCTGTCTGCCCTGCGACCACGTGCACTGCCTGCGCTGCCTCAGGGCCTGGTTTGCCTCA
GAGCAGATGATATGCCCCTACTGTTTAACTGCCTTGCCAGACGAATTCTCTCCAGCTGTTTCCCAAGCGCACAGGGAAGCCATTGAAAAG
CATGCCCGCTTCCGGCAGATGTGCAACAGTTTCTTCGTAGACCTGGTGTCCACCATTTGCTTCAAGGACAACGCTCCGCCTGAGAAGGAA
GTGATTGAGAGCCTGCTCTCTCTCCTCTTCGTCCAAAAGGGGCGCTTAAGAGATGCTGCCCAGAGACACTGTGAACACACAAAATCTCTC
TCTCCATTCAATGATGTTGTGGATAAGACTCCTGTCATCCGCTCAGTGATACTGAAACTGCTTTTGAAGTACAGCTTTCATGATGTAAAA
GATTATATTCAGGAATATTTGACCCTGTTAAAAAAGAAAGCATTCATAACTGAAGATAAAACTGAACTGTACATGCTCTTCATCAACTGC
CTGGAGGATTCAATACTTGAGAAGACCAGTGCTTACTCCAGAAATGATGAACTGAACCACCTAGAAGAGGAAGGTCGTTTCCTTAAGGCA
TATTCTCCAGCAAGCCGGGGCCGAGAGCCTGCCAACGAGGCCTCGGTTGAATACCTGCAAGAGGTGGCCCGGATCCGCCTCTGCCTCGAC
AGAGCTGCAGATTTCCTCTCGGAGCCTGAGGGAGGCCCAGAGATGGCCAAGGAGAAGCAGTGCTACCTGCAGCAAGTCAAGCAGTTCTGT
ATCCGGGTGGAGAACGACTGGCACCGGGTGTACCTGGTGCGGAAGCTCAGCAGCCAGCGGGGGATGGAGTTCGTGCAGGGCCTCTCCAAG
CCCGGCCGCCCGCACCAGTGGGTGTTTCCCAAGGACGTTGTCAAGCAGCAGGGGCTGCGGCAGGACCACCCAGGCCAGATGGATAGGTAC
CTGGTGTACGGCGATGAATACAAGGCTCTCCGTGATGCTGTGGCCAAAGCTGTCCTCGAGTGCAAGCCACTGGGCATTAAGACTGCTCTG
AAGGCCTGCAAGACCCCCCAAAGCCAGCAGTCAGCCTACTTCCTGTTAACACTGTTTAGAGAGGTGGCTATTTTGTACAGATCCCACAAT
GCAAGCCTCCACCCCACGCCAGAGCAATGTGAAGCTGTGAGCAAATTCATTGGCGAATGCAAGATCCTTTCACCTCCTGATATCAGCCGT
TTTGCAACATCGCTCGTGGACAATTCTGTGCCATTGTTGAGGGCGGGGCCTAGTGACAGCAACCTTGATGGAACGGTGACAGAAATGGCC
ATTCATGCTGCAGCCGTCCTTCTGTGTGGACAGAATGAACTCTTGGAGCCCCTAAAGAATCTGGCCTTCTCCCCAGCCACCATGGCGCAT
GCTTTTCTTCCAACCATGCCTGAAGACTTGCTGGCTCAAGCTCGGAGGTGGAAGGGTCTGGAGCGAGTCCACTGGTACACTTGTCCCAAC
GGCCATCCTTGCTCCGTGGGAGAGTGTGGCAGGCCGATGGAACAGAGCATCTGCATTGACTGCCATGCGCCGATTGGAGGCATTGACCAC
AAACCTCGGGACGGCTTTCATCTGGTCAAAGACAAGGCAGACAGAACGCAGACCGGCCACGTGCTGGGCAACCCGCAGCGGAGAGACGTG
GTGACATGTGACCGAGGGCTGCCCCCAGTGGTCTTCCTCCTTATCCGGCTACTCACTCACTTGGCTCTGCTTCTGGGAGCGTCCCAGAGT
TCCCAGATCAGTCGCATCGAATACATTCATTCAAAGAACTTCATCCACCGGGATGTGAAGCCAGACAACTTCCTCATGGGCCTGGGGAAG
AAGGGCAACCTGGTGTACATCATCGACTTCGGGCTGGCCAAGAAGTACCGGGATGCACGCACCCACCAGCACATCCCCTATCGTGAGAAC
AAGAACCTCACGGGGACGGCGCGGTACGCCTCCATCAACACGCACCTTGGAATTGAACAATCCCGAAGAGATGACTTGGAGTCTCTGGGC
TACGTGCTAATGTACTTCAACCTGGGCTCTCTCCCCTGGCAGGGGCTGAAGGCTGCCACCAAGAGACAGAAATACGAAAGGATTAGCGAG
AAGAAAATGTCCACCCCCATCGAAGTGTTGTGTAAAGGCTACCCTTCCGAATTTGCCACATACCTGAATTTCTGCCGTTCCTTGCGTTTT
GACGACAAGCCTGACTACTCGTACCTGCGGCAGCTTTTCCGGAATCTGTTCCATCGCCAGGGCTTCTCCTATGACTACGTGTTCGACTGG
AACATGCTCAAATTTGGTGCCAGCCGGGCCGCCGATGACGCCGAGCGGGAGCGCAGGGACCGAGAGGAGCGGCTGAGACACTCGCGGAAC
CCGGCTACCCGCGGCCTCCCTTCCACAGCCTCCGGCCGCCTGCGGGGGACGCAGGAAGTGGCTCCCCCCACACCCCTCACCCCTACCTCA
CACACGGCTAACACCTCCCCCCGGCCCGTCTCCGGCATGGAGAGAGAGCGGAAAGTGAGTATGCGGCTGCACCGCGGGGCCCCCGTCAAC
ATCTCCTCGTCCGACCTCACAGGCCGACAAGATACCTCTCGCATGTCCACCTCACAGAGGAGCAGGGACATGGCATCTCTCCGGCTGCAC
GCGGCCCGCCAGGGCACCCGCTGCCGTCCCCAGCGCCCACGACGCACCTACTGAGGGCCCCGGCGGCCTCTGACCGGGCTCCCAGCCACG
CAGGCCACTGCTGGCCACGAGGGCAGGTGGGTGTTAGGTGTCCAGGACAAGCCCAAGCGCTGGGCCGGGCTGGATGGAGGACAGGGTGCA
AAGACCAGCCCTGGGCACTGACCACACCACGCACACTGCCAGCCAGGCAGAGGGGCGAAAAAGGGAAGGCAGGAGGGTCCTGTTTCTTAA

>74967_74967_3_RNF213-CSNK1D_RNF213_chr17_78354787_ENST00000336301_CSNK1D_chr17_80211120_ENST00000398519_length(amino acids)=2987AA_BP=2670
MVCDGDWEHCYLPSAFSQHKVFVTPQAPLEAIQAYLAGHYRVPKQTLSAAAVFNDRLCVGIVASERAGVGKSLYVKRLHDKMKMQLNVKN
VPLKTIRLIDPQVDESRVLGALLPFLDAQYQKVPVLFHLDVTSSVQTGIWVFLFKLLILQYLMDINGKMWLRNPCHLYIVEILERRTSVP
SRSSSALRTRVPQFSFLDIFPKVTCRPPKEVIDMELSALRSDTEPGMDLWEFCSETFQRPYQYLRRFNQNQDLDTFQYQEGSVEGTPEEC
LQHFLFHCGVINPSWSELRNFARFLNYQLRDCEASLFCNPSFIGDTLRGFKKFVVTFMIFMARDFATPSLHTSDQSPGKHMVTMDGVREE
DLAPFSLRKRWESEPHPYVFFNDDHTTMTFIGFHLQPNINGSVDAISHLTGKVIKRDVMTRDLYQGLLLQRVPFNVDFDKLPRHKKLERL
CLTLGIPQATDPDKTYELTTDNMLKILAIEMRFRCGIPVIIMGETGCGKTRLIKFLSDLRRGGTNADTIKLVKVHGGTTADMIYSRVREA
ENVAFANKDQHQLDTILFFDEANTTEAISCIKEVLCDHMVDGQPLAEDSGLHIIAACNPYRKHSEEMICRLESAGLGYRVSMEETADRLG
SIPLRQLVYRVHALPPSLIPLVWDFGQLSDVAEKLYIQQIVQRLVESISLDENGTRVITEVLCASQGFMRKTEDECSFVSLRDVERCVKV
FRWFHEHSAMLLAQLNAFLSKSSVSKNHTERDPVLWSLMLAIGVCYHASLEKKDSYRKAIARFFPKPYDDSRLLLDEITRAQDLFLDGVP
LRKTIAKNLALKENVFMMVVCIELKIPLFLVGKPGSSKSLAKTIVADAMQGPAAYSDLFRSLKQVHLVSFQCSPHSTPQGIISTFRQCAR
FQQGKDLQQYVSVVVLDEVGLAEDSPKMPLKTLHPLLEDGCIEDDPAPHKKVGFVGISNWALDPAKMNRGIFVSRGSPNETELIESAKGI
CSSDILVQDRVQGYFASFAKAYETVCKRQDKEFFGLRDYYSLIKMVFAAAKASNRKPSPQDIAQAVLRNFSGKDDIQALDIFLANLPEAK
CSEEVSPMQLIKQNIFGPSQKVPGGEQEDAESRYLLVLTKNYVALQILQQTFFEGDQQPEIIFGSGFPKDQEYTQLCRNINRVKICMETG
KMVLLLNLQNLYESLYDALNQYYVHLGGQKYVDLGLGTHRVKCRVHPNFRLIVIEEKDVVYKHFPIPLINRLEKHYLDINTVLEKWQKSI
VEELCAWVEKFINVKAHHFQKRHKYSPSDVFIGYHSDACASVVLQVIERQGPRALTEELHQKVSEEAKSILLNCATPDAVVRLSAYSLGG
FAAEWLSQEYFHRQRHNSFADFLQAHLHTADLERHAIFTEITTFSRLLTSHDCEILESEVTGRAPKPTLLWLQQFDTEYSFLKEVRNCLT
NTAKCKILIFQTDFEDGIRSAQLIASAKYSVINEINKIRENEDRIFVYFITKLSRVGRGTAYVGFHGGLWQSVHIDDLRRSTLMVSDVTR
LQHVTISQLFAPGDLPELGLEHRAEDGHEEAMETEASTSGEVAEVAEEAMETESSEKVGKETSELGGSDVSILDTTRLLRSCVQSAVGML
RDQNESCTRNMRRVVLLLGLLNEDDACHASFLRVSKMRLSVFLKKQEESQFHPLEWLAREACNQDALQEAGTFRHTLWKRVQGAVTPLLA
SMISFIDRDGNLELLTRPDTPPWARDLWMFIFSDTMLLNIPLVMNNERHKGEMAYIVVQNHMNLSENASNNVPFSWKIKDYLEELWVQAQ
YITDAEGLPKKFVDIFQQTPLGRFLAQLHGEPQQELLQCYLKDFILLTMRVSTEEELKFLQMALWSCTRKLKAASEAPEEEVSLPWVHLA
YQRFRSRLQNFSRILTIYPQVLHSLMEARWNHELAGCEMTLDAFAAMACTEMLTRNTLKPSPQAWLQLVKNLSMPLELICSDEHMQGSGS
LAQAVIREVRAQWSRIFSTALFVEHVLLGTESRVPELQGLVTEHVFLLDKCLRENSDVKTHGPFEAVMRTLCECKETASKTLSRFGIQPC
SICLGDAKDPVCLPCDHVHCLRCLRAWFASEQMICPYCLTALPDEFSPAVSQAHREAIEKHARFRQMCNSFFVDLVSTICFKDNAPPEKE
VIESLLSLLFVQKGRLRDAAQRHCEHTKSLSPFNDVVDKTPVIRSVILKLLLKYSFHDVKDYIQEYLTLLKKKAFITEDKTELYMLFINC
LEDSILEKTSAYSRNDELNHLEEEGRFLKAYSPASRGREPANEASVEYLQEVARIRLCLDRAADFLSEPEGGPEMAKEKQCYLQQVKQFC
IRVENDWHRVYLVRKLSSQRGMEFVQGLSKPGRPHQWVFPKDVVKQQGLRQDHPGQMDRYLVYGDEYKALRDAVAKAVLECKPLGIKTAL
KACKTPQSQQSAYFLLTLFREVAILYRSHNASLHPTPEQCEAVSKFIGECKILSPPDISRFATSLVDNSVPLLRAGPSDSNLDGTVTEMA
IHAAAVLLCGQNELLEPLKNLAFSPATMAHAFLPTMPEDLLAQARRWKGLERVHWYTCPNGHPCSVGECGRPMEQSICIDCHAPIGGIDH
KPRDGFHLVKDKADRTQTGHVLGNPQRRDVVTCDRGLPPVVFLLIRLLTHLALLLGASQSSQISRIEYIHSKNFIHRDVKPDNFLMGLGK
KGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISE
KKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGASRAADDAERERRDREERLRHSRN
PATRGLPSTASGRLRGTQEVAPPTPLTPTSHTANTSPRPVSGMERERKVSMRLHRGAPVNISSSDLTGRQDTSRMSTSQRSRDMASLRLH

--------------------------------------------------------------
>74967_74967_4_RNF213-CSNK1D_RNF213_chr17_78354787_ENST00000508628_CSNK1D_chr17_80211120_ENST00000314028_length(transcript)=17115nt_BP=14089nt
GACAGCGCGCGGCAGGCGGCGAGCTCGGGGGCCGCAGAAAATGAAACTGAAGCCGTGGTCACGTGACAGGACATGTAGTATATAGCAGGC
TGCCAGCGACTCCTGCTCTTGCTTCTGGATCTGCAGGGCAGTCCCAGCAGGACCCATGGAGTGTCCTTCGTGCCAGCATGTCTCCAAGGA
GGAAACCCCCAAGTTCTGCAGCCAGTGCGGAGAGAGGCTGCCTCCTGCAGCCCCCATAGCAGATTCTGAGAACAATAACTCCACAATGGC
GTCGGCCTCGGAGGGTGAAATGGAGTGTGGGCAGGAGCTGAAGGAGGAAGGGGGCCCGTGCTTGTTCCCGGGCTCAGACAGTTGGCAAGA
AAACCCCGAGGAGCCCTGTTCCAAAGCCTCCTGGACCGTCCAAGAAGGAGCTACATCAGAGGTTTTGGTAGATGCTGCTGTAGACCTCAT
ATCCGATGAATGGGAAGCTGCTAATGCCATACCCAGCAAGAGAAGGAAGCAGGATGCAGCCCCGCTTGAGGCCGCCAGCGTGCCTTCTGC
AGACTGTGAGCAGAGCAAAAAGAAGAAAAGGAAGAAGAAAAAGAAGGGGAACAAGTCCGCTTCCTCAGAGCTGGCTTCCTTGCCCCTTTC
TCCTGCCAGCCCCTGTCACCTGACTTTGCTTTCAAACCCGTGGCCTCAGGACACAGCCCTGCCCCACAGCCAAGCCCAGCAGAGTGGCCC
CACTGGCCAGCCGAGCCAGCCCCCAGGCACAGCCACCACGCCACTGGAGGGTGACGGCCTCTCCGCGCCCACCGAGGTTGGCGACAGCCC
CCTGCAGGCCCAGGCTTTGGGAGAGGCAGGAGTGGCCACAGGAAGTGAGGCTCAGAGCAGCCCGCAATTCCAGGACCACACGGAAGGGGA
GGACCAGGACGCTTCCATCCCCTCTGGGGGCAGAGGCCTGTCCCAGGAGGGGACCGGTCCCCCCACCTCTGCTGGTGAAGGCCATTCTAG
GACTGAAGATGCTGCCCAGGAGCTCCTGTTGCCTGAGTCAAAAGGAGGCAGCTCTGAGCCCGGGACAGAACTGCAGACCACCGAGCAACA
GGCAGGGGCCTCAGCCTCTATGGCAGTTGATGCTGTAGCTGAGCCAGCCAATGCAGTTAAAGGGGCCGGGAAGGAAATGAAAGAGAAGAC
CCAGAGAATGAAACAGCCACCAGCAACCACTCCTCCTTTCAAAACACACTGCCAGGAAGCTGAGACCAAGACCAAGGACGAGATGGCTGC
TGCTGAAGAAAAAGTCGGTAAGAATGAACAAGGGGAGCCTGAAGACCTCAAGAAGCCAGAGGGGAAGAACAGAAGTGCAGCTGCTGTGAA
AAACGAGAAGGAGCAAAAAAACCAGGAAGCAGATGTCCAGGAAGTGAAGGCAAGCACGCTGAGCCCGGGTGGAGGAGTCACCGTGTTCTT
CCACGCCATCATCTCTCTTCATTTCCCATTCAATCCTGACCTCCATAAAGTCTTCATCAGAGGAGGAGAAGAATTTGGGGAGTCAAAATG
GGACAGCAATATCTGTGAGCTGCACTACACCAGAGACTTGGGTCATGACCGCGTTCTTGTTGAAGGCATTGTCTGCATTTCCAAGAAGCA
CCTAGATAAATACATTCCTTACAAGTACGTCATTTATAATGGGGAATCTTTTGAGTATGAGTTCATTTACAAGCACCAGCAGAAGAAGGG
CGAGTACGTCAACCGCTGTCTGTTCATAAAATCTTCACTTCTGGGCTCAGGAGACTGGCATCAGTACTATGACATAGTTTATATGAAGCC
TCATGGGAGACTCCAGAAAGTCATGAACCACATCACAGACGGGCCGAGGAAGGACCTGGTGAAGGGGAAGCAGATTGCCGCTGCGCTCAT
GCTGGACAGCACCTTCAGCATCCTGCAGACCTGGGACACCATCAACCTGAACAGCTTCTTCACCCAGTTCGAGCAGTTTTGCTTTGTCCT
GCAACAGCCTATGATTTATGAAGGACAGGCACAGCTGTGGACCGATTTGCAGTACAGGGAGAAAGAGGTGAAGAGATACCTGTGGCAACA
TCTGAAAAAACACGTGGTACCATTGCCGGACGGAAAAAGCACGGACTTTTTGCCTGTGGACTGCCCAGTGAGGAGTAAACTGAAAACAGG
CCTGATTGTCCTTTTTGTAGTGGAAAAAATTGAGCTTTTATTAGAAGGCAGCCTGGACTGGTTGTGTCACCTCCTAACCTCAGATGCCAG
CTCACCAGATGAGTTTCACCGTGACCTAAGCCACATCCTTGGGATACCTCAGAGCTGGCGGCTGTACCTGGTGAACCTGTGCCAAAGATG
CATGGACACAAGGACGTACACCTGGCTGGGCGCCCTGCCTGTCCTGCACTGCTGTATGGAGCTGGCCCCGCGGCACAAGGATGCCTGGAG
ACAGCCTGAGGACACCTGGGCCGCTCTGGAGGGACTCTCCTTCTCACCGTTCCGGGAACAAATGCTAGATACGAGTTCCCTACTTCAGTT
TATGAGAGAGAAGCAGCATTTGCTGAGCATAGACGAGCCTCTCTTCCGGTCCTGGTTTAGTCTGCTACCTCTGAGTCACCTGGTTATGTA
TATGGAAAACTTCATTGAGCACCTGGGTCGTTTTCCTGCTCATATCCTGGACTGTCTTTCAGGGATTTACTACCGGCTTCCGGGACTTGA
GCAAGTCTTGAATACGCAGGATGTTCAGGATGTTCAGAACGTTCAGAACATTTTAGAAATGCTGTTGCGACTCCTGGACACTTACCGGGA
CAAGATTCCCGAGGAGGCCTTGTCACCATCCTACCTGACTGTGTGTCTGAAACTGCATGAAGCCATCTGCAGCAGCACAAAGCTACTTAA
GTTTTACGAGCTGCCAGCCTTATCTGCCGAGATTGTCTGCAGAATGATTAGACTTCTATCTCTGGTGGATTCTGCAGGACAGAGAGATGA
AACTGGAAATAATTCAGTCCAAACAGTCTTCCAAGGGACCCTTGCTGCTACGAAAAGGTGGCTCCGAGAAGTTTTTACAAAGAACATGCT
CACATCTTCAGGTGCCTCATTCACATACGTCAAGGAAATTGAGGTCTGGAGGCGGCTGGTGGAAATCCAATTCCCCGCGGAGCATGGCTG
GAAGGAGTCGTTGCTGGGAGACATGGAATGGAGGCTCACAAAGGAGGAACCCCTCTCCCAGATCACTGCCTACTGCAATAGTTGCTGGGA
CACCAAAGGCTTAGAGGACAGTGTGGCCAAGACCTTCGAGAAATGCATCATTGAAGCCGTGAGCTCAGCCTGCCAGTCTCAGACCAGTAT
CCTTCAGGGGTTCTCTTACTCTGATTTGCGGAAATTTGGCATCGTCTTGTCTGCTGTGATCACTAAGTCCTGGCCTAGGACCGCGGACAA
CTTCAATGACATTTTAAAGCATCTGCTCACGTTGGCAGATGTCAAGCACGTCTTCAGATTGTGTGGAACCGACGAGAAAATACTAGCAAA
TGTCACAGAGGATGCCAAGAGGCTGATAGCTGTTGCCGACTCTGTGTTGACGAAAGTTGTTGGTGACCTCCTAAGTGGCACGATTTTAGT
TGGACAACTGGAGCTGATTATAAAGCACAAGAATCAGTTTCTTGACATCTGGCAACTGAGGGAAAAAAGTCTTTCACCCCAGGATGAACA
ATGTGCTGTGGAGGAAGCACTGGATTGGAGAAGGGAGGAACTGTTACTTCTAAAGAAAGAGAAAAGATGTGTTGATAGTCTCCTGAAGAT
GTGTGGGAACGTGAAACATCTGATACAAGTGGACTTTGGAGTGCTTGCAGTAAGACACTCACAAGACCTCAGCAGTAAAAGATTAAATGA
CACCGTGACAGTGAGACTGTCCACCTCCTCGAACTCGCAGAGGGCAACGCATTACCACCTGAGCTCCCAGGTCCAAGAAATGGCTGGGAA
GATAGACTTGCTCAGAGACAGCCACATCTTCCAGCTCTTCTGGCGGGAAGCCGCAGAGCCGCTGAGTGAGCCTAAGGAGGACCAGGAAGC
CGCAGAGTTGCTGAGTGAGCCCGAAGAAGAATCAGAAAGGCACATCCTTGAGCTTGAAGAGGTGTATGACTATTTGTATCAGCCTTCTTA
CAGAAAGTTCATTAAGTTGCACCAGGATCTAAAGTCAGGAGAGGTCACCCTTGCAGAGATTGATGTCATCTTCAAGGACTTTGTGAATAA
ATACACGGACCTGGATTCAGAACTTAAGATCATGTGCACCGTGGACCACCAGGACCAAAGAGATTGGATCAAGGACCGAGTCGAACAGAT
CAAGGAATACCATCACCTGCACCAGGCTGTCCACGCAGCCAAGGTCATCTTGCAGGTCAAAGAGAGCCTGGGACTGAACGGTGACTTCAG
TGTTCTCAACACTTTACTAAATTTTACTGATAACTTCGACGACTTTCGCCGTGAAACACTGGACCAGATCAACCAGGAGCTCATCCAGGC
CAAAAAGCTGCTCCAGGACATCAGCGAGGCCCGGTGCAAGGGGCTGCAGGCTCTGTCCCTGAGAAAGGAGTTCATCTGCTGGGTCCGGGA
GGCTCTTGGAGGCATCAATGAGCTGAAGGTGTTTGTGGACCTGGCCTCCATCTCAGCGGGGGAGAATGACATTGATGTGGACCGGGTGGC
CTGCTTCCATGACGCTGTGCAGGGCTACGCATCCCTGCTATTTAAGCTGGACCCCAGCGTGGACTTCAGTGCATTCATGAAGCATCTGAA
AAAGCTGTGGAAGGCTCTGGATAAGGACCAGTACCTGCCCAGGAAACTGTGTGACTCCGCCAGGAACTTGGAATGGCTGAAGACTGTGAA
TGAGAGTCATGGGTCTGTGGAACGCTCATCCCTGACCCTGGCCACGGCCATCAACCAAAGAGGCATCTATGTGATCCAGGCGCCCAAAGG
TGGCCAAAAGATTTCCCCAGACACGGTTCTGCACTTGATCCTTCCTGAGAGCCCTGGCAGCCACGAGGAGTCACGAGAGTACTCTTTAGA
GGAGGTGAAGGAGCTTTTGAACAAGTTGATGCTGATGTCTGGCAAGAAGGATCGTAACAACACGGAAGTGGAGAGGTTTTCAGAGGTCTT
CTGCAGTGTGCAGAGGCTCAGCCAGGCCTTCATCGACCTGCACTCTGCTGGGAATATGCTGTTCAGGACGTGGATCGCCATGGCCTACTG
CTCCCCCAAGCAGGGTGTGTCCCTCCAAATGGACTTTGGCTTGGACCTGGTGACGGAGCTTAAAGAAGGTGGAGATGTCACTGAGCTGCT
GGCAGCCCTCTGCAGGCAGATGGAGCACTTCCTTGACAGCTGGAAGAGATTTGTGACCCAGAAGCGAATGGAGCACTTTTACCTGAACTT
CTACACGGCAGAGCAGCTGGTTTACCTGAGCACTGAGCTCAGGAAGCAGCCCCCGAGTGATGCCGCCCTAACGATGCTATCCTTCATCAA
AAGCAACTGCACCCTGAGGGATGTCTTAAGGGCCTCTGTGGGGTGTGGGAGTGAGGCCGCCAGGTACCGCATGAGGAGAGTCATGGAAGA
GCTCCCGCTGATGCTCTTATCAGAGTTCAGCCTGGTGGACAAGCTGAGGATCATCATGGAGCAGTCCATGAGGTGCCTTCCTGCCTTCCT
GCCCGACTGCCTCGACCTAGAGACCCTTGGCCACTGTCTGGCTCACCTGGCAGGGATGGGTGGGTCTCCCGTGGAGCGTTGTCTCCCGAG
AGGTCTGCAGGTCGGCCAGCCCAACCTCGTCGTCTGTGGCCACTCCGAGGTGTTGCCAGCCGCCCTGGCTGTCTACATGCAAACCCCAAG
CCAGCCCCTGCCCACTTACGATGAGGTGCTGCTCTGCACCCCGGCAACCACCTTTGAGGAGGTGGCACTGTTGCTGCGCCGCTGCCTGAC
CCTGGGCTCCCTGGGGCACAAGGTCTACAGCCTGCTGTTCGCAGATCAGCTGAGCTACGAGGTGGCACGCCAAGCGGAGGAGCTTTTCCA
CAATCTGTGCACGCAGCAGCACCGAGAAGACTACCAGCTCGTCATGGTCTGTGATGGGGACTGGGAGCACTGCTACCTCCCCTCTGCCTT
CAGCCAGCACAAGGTCTTCGTCACCCCCCAGGCACCCCTCGAGGCCATCCAAGCCTACCTGGCAGGTCACTACCGGGTCCCGAAGCAGAC
CCTGTCGGCGGCAGCCGTGTTCAATGACCGGCTGTGTGTTGGGATCGTGGCCTCGGAGCGAGCAGGTGTTGGAAAGTCTCTGTACGTGAA
GAGGTTGCACGACAAAATGAAGATGCAGTTAAACGTGAAAAATGTGCCTCTGAAAACAATTCGACTGATCGACCCTCAGGTGGATGAGAG
CCGAGTCCTGGGCGCCCTGCTGCCCTTCCTGGATGCGCAGTATCAGAAGGTCCCCGTGCTCTTTCACCTGGACGTGACCTCCTCAGTGCA
GACTGGAATTTGGGTGTTTCTTTTCAAGCTCCTCATTTTACAATACTTAATGGATATAAATGGGAAAATGTGGCTTCGGAACCCCTGCCA
TTTGTATATCGTTGAAATCCTGGAAAGGAGGACGTCAGTGCCGTCGAGGAGCTCTTCAGCGCTGCGTACACGTGTACCCCAGTTCAGTTT
TCTTGACATCTTCCCAAAAGTCACCTGCAGGCCTCCCAAAGAGGTGATAGACATGGAGCTGAGTGCCCTGAGGAGTGACACAGAGCCTGG
GATGGATCTGTGGGAGTTCTGCAGCGAAACTTTCCAAAGACCTTACCAGTATTTAAGACGATTCAATCAAAACCAAGACCTAGACACGTT
TCAGTATCAAGAAGGCTCTGTCGAAGGCACCCCGGAGGAATGCCTCCAGCATTTCCTGTTTCACTGCGGGGTAATAAACCCATCCTGGTC
AGAGCTTCGGAACTTTGCTCGGTTCCTGAATTATCAGCTCAGAGATTGTGAGGCCTCTCTCTTCTGCAATCCGAGTTTTATTGGCGACAC
ACTGAGGGGCTTCAAGAAGTTCGTGGTGACCTTCATGATCTTTATGGCAAGAGATTTTGCCACACCATCACTCCACACCTCTGACCAAAG
CCCGGGGAAGCACATGGTCACCATGGATGGGGTTAGGGAAGAAGATCTAGCGCCCTTCTCCCTCCGGAAGAGGTGGGAGTCGGAGCCTCA
CCCATACGTTTTCTTCAATGACGACCACACAACCATGACATTCATCGGCTTCCATCTGCAGCCCAACATCAACGGCAGTGTCGATGCCAT
CAGTCACTTGACTGGGAAGGTCATCAAGAGAGACGTCATGACCAGGGACCTGTACCAGGGCCTGCTGCTCCAGAGGGTGCCCTTCAATGT
CGACTTTGATAAACTGCCCAGACACAAGAAACTTGAGAGGCTCTGCCTGACCTTAGGGATCCCCCAGGCCACCGACCCCGACAAAACGTA
TGAGCTCACAACCGACAATATGCTTAAAATCCTTGCCATCGAGATGCGGTTCCGGTGTGGGATCCCGGTTATCATCATGGGAGAAACTGG
CTGTGGGAAAACCAGGCTTATTAAATTCCTTAGCGACCTGCGGCGTGGTGGTACCAATGCTGACACCATAAAGCTGGTCAAGGTGCACGG
AGGAACAACTGCAGACATGATCTACTCCAGAGTCAGGGAGGCTGAAAATGTGGCCTTCGCCAATAAGGACCAACATCAGTTGGACACCAT
CTTGTTTTTTGATGAAGCCAACACAACGGAAGCTATAAGCTGTATCAAAGAAGTCCTGTGTGATCATATGGTGGATGGCCAGCCTCTGGC
TGAGGACTCTGGCCTGCATATTATAGCTGCCTGCAATCCATACCGGAAGCACTCTGAGGAGATGATCTGCCGTTTGGAGTCAGCTGGTTT
GGGCTACAGGGTTAGTATGGAGGAGACGGCCGACAGGCTGGGCTCCATTCCTCTGAGGCAGCTGGTATACCGGGTCCATGCTCTGCCCCC
GAGCCTGATTCCTCTGGTGTGGGACTTTGGACAACTGAGTGACGTTGCTGAAAAGCTCTACATCCAGCAGATTGTCCAGAGACTGGTTGA
GTCCATCAGCCTAGATGAAAACGGGACTCGCGTGATCACAGAAGTCCTCTGCGCCTCTCAGGGTTTCATGAGGAAAACAGAAGATGAGTG
CAGCTTTGTCAGCCTCAGGGACGTGGAGCGCTGTGTGAAAGTTTTCAGGTGGTTCCACGAGCACAGCGCGATGCTCTTAGCGCAGCTGAA
TGCCTTTCTCTCCAAGTCCAGCGTCAGCAAAAATCACACCGAGAGAGATCCCGTCCTCTGGTCGTTGATGCTGGCCATCGGGGTGTGTTA
CCATGCCTCTTTAGAAAAGAAAGACTCATATCGGAAAGCCATCGCCAGGTTCTTTCCGAAACCGTATGACGACAGCAGGCTGCTTCTGGA
TGAAATAACACGGGCACAGGATCTTTTTCTGGACGGCGTACCTCTGAGGAAAACCATCGCCAAGAACTTGGCCTTGAAGGAGAACGTCTT
CATGATGGTCGTCTGCATCGAGCTGAAGATTCCCCTCTTCCTGGTGGGGAAGCCCGGCAGCTCCAAGTCTCTCGCCAAGACCATCGTGGC
AGACGCCATGCAGGGCCCGGCTGCCTACTCAGATCTCTTCCGCAGCCTGAAGCAGGTCCACCTGGTGTCCTTCCAGTGCAGCCCGCACTC
CACCCCACAGGGCATCATCAGCACCTTCCGGCAGTGCGCCCGCTTTCAGCAGGGGAAGGACCTGCAGCAGTACGTCTCTGTGGTGGTGTT
AGATGAGGTGGGGCTGGCGGAAGACTCACCCAAAATGCCCCTGAAGACTCTGCACCCGCTGCTGGAAGACGGATGCATTGAAGACGATCC
CGCCCCCCACAAAAAGGTCGGCTTCGTGGGCATCTCCAACTGGGCCCTTGACCCTGCCAAGATGAACCGGGGCATTTTTGTGTCACGTGG
CAGCCCCAACGAGACAGAGCTCATAGAGAGCGCCAAGGGCATCTGCTCCTCAGACATCCTCGTCCAGGACCGAGTCCAAGGGTACTTTGC
GTCCTTTGCCAAAGCCTACGAAACGGTGTGTAAGCGCCAGGACAAGGAATTCTTCGGGCTTCGTGACTACTACAGCCTCATCAAAATGGT
CTTTGCTGCAGCAAAGGCTTCAAATAGAAAGCCTTCCCCGCAAGACATTGCACAGGCTGTCCTTAGGAACTTCAGTGGCAAGGATGACAT
CCAAGCTTTGGACATCTTTCTGGCCAATTTGCCCGAGGCCAAGTGCTCAGAGGAAGTCAGCCCCATGCAGCTGATCAAACAGAACATCTT
TGGGCCTTCTCAGAAGGTGCCGGGTGGAGAGCAGGAAGATGCTGAGTCCCGCTACTTACTCGTGCTGACCAAAAACTACGTGGCACTGCA
GATCCTGCAGCAGACATTCTTCGAGGGGGACCAGCAGCCGGAGATTATTTTTGGTTCTGGTTTCCCCAAGGACCAAGAGTACACCCAGCT
CTGCAGAAACATCAATCGTGTGAAGATCTGCATGGAAACAGGCAAGATGGTGTTGCTTCTCAACCTGCAGAACCTCTACGAGAGCCTCTA
CGACGCACTCAACCAGTACTACGTCCACCTCGGCGGCCAGAAGTACGTGGACCTCGGTCTGGGGACCCACCGCGTCAAATGTCGGGTTCA
CCCCAACTTCCGCCTGATTGTCATTGAAGAGAAAGACGTCGTGTACAAACACTTTCCCATCCCCCTCATTAACCGGCTGGAGAAGCACTA
TCTGGATATCAACACGGTGCTGGAGAAATGGCAGAAGAGCATCGTGGAGGAGCTCTGTGCGTGGGTGGAGAAGTTCATCAATGTCAAAGC
ACATCATTTCCAGAAGAGGCACAAATACAGCCCCTCTGACGTCTTCATCGGCTACCACTCGGACGCCTGCGCGTCTGTGGTGCTGCAGGT
CATAGAGAGGCAGGGTCCCCGGGCCTTGACGGAGGAACTTCACCAGAAGGTGTCTGAGGAGGCCAAATCGATCCTGCTGAACTGCGCTAC
GCCCGATGCCGTGGTCCGGCTGAGCGCCTACTCGCTGGGCGGGTTCGCAGCGGAGTGGCTGTCGCAGGAGTACTTTCACAGACAGAGGCA
CAACTCCTTTGCAGATTTCCTTCAGGCACACCTGCACACGGCAGACCTGGAGCGCCACGCCATCTTCACAGAGATCACCACTTTCTCCAG
GCTGCTAACAAGTCACGACTGTGAAATTTTAGAATCAGAGGTCACAGGCAGGGCTCCGAAACCCACACTCCTGTGGCTGCAGCAGTTTGA
CACCGAGTACTCATTCCTCAAAGAAGTCCGAAACTGTTTAACGAATACAGCCAAATGTAAAATCCTCATTTTTCAGACAGATTTTGAAGA
TGGAATCCGTAGCGCCCAGCTCATTGCCTCAGCTAAGTATTCTGTTATAAATGAAATCAACAAAATACGAGAAAATGAGGACCGTATCTT
CGTCTATTTCATCACAAAACTGTCCCGGGTGGGAAGAGGAACAGCCTATGTGGGCTTCCACGGAGGGCTGTGGCAGTCTGTCCACATCGA
TGACCTCCGGAGATCCACCCTCATGGTTTCTGATGTGACCAGGCTGCAGCATGTCACCATCAGCCAGCTGTTCGCGCCCGGAGACTTGCC
TGAGCTGGGCTTGGAACACCGGGCGGAAGACGGCCATGAGGAGGCGATGGAGACGGAGGCCAGCACATCAGGGGAGGTGGCAGAGGTGGC
AGAGGAGGCCATGGAAACAGAAAGTTCTGAGAAGGTGGGAAAGGAAACCTCTGAACTCGGAGGCAGTGATGTGTCGATCCTGGACACCAC
CAGGCTGCTGAGAAGCTGTGTGCAGAGCGCCGTGGGCATGCTCAGAGACCAGAACGAGAGCTGCACGCGCAATATGCGGAGGGTGGTGCT
CCTCCTGGGCCTCTTGAATGAGGATGACGCGTGCCACGCCTCTTTCTTGCGGGTATCCAAGATGCGCCTCAGTGTCTTTTTAAAGAAGCA
AGAAGAGAGCCAGTTTCACCCTCTGGAGTGGTTGGCAAGGGAAGCCTGCAACCAGGACGCTCTCCAGGAGGCGGGCACATTCAGGCACAC
CCTCTGGAAGCGGGTCCAAGGTGCTGTCACCCCTCTGCTGGCGAGCATGATATCATTCATCGACAGAGACGGCAACCTAGAGTTACTGAC
CAGGCCAGATACTCCGCCCTGGGCAAGAGATCTTTGGATGTTTATTTTCAGTGACACGATGCTTCTGAACATTCCTCTTGTGATGAATAA
TGAAAGACATAAAGGTGAGATGGCCTACATCGTGGTGCAGAACCACATGAACCTTTCCGAGAACGCTTCCAACAACGTCCCTTTCAGCTG
GAAAATCAAGGACTATCTGGAGGAGCTGTGGGTCCAGGCTCAGTACATCACAGACGCAGAAGGACTGCCCAAGAAGTTCGTGGACATCTT
TCAGCAGACTCCTCTGGGCAGGTTTCTTGCCCAGCTCCATGGAGAGCCGCAGCAGGAACTTCTTCAGTGTTACTTGAAGGATTTCATTCT
CTTGACCATGCGTGTGTCAACGGAGGAGGAATTAAAGTTTCTGCAGATGGCTCTGTGGTCCTGCACTAGGAAACTGAAAGCGGCGTCAGA
AGCGCCCGAGGAAGAGGTTTCCTTACCGTGGGTGCACCTTGCCTACCAGCGTTTCAGAAGCCGTCTGCAGAACTTTTCCAGAATCCTGAC
CATCTACCCTCAGGTTCTCCACAGCCTGATGGAAGCCCGTTGGAACCATGAGCTGGCTGGATGTGAGATGACCCTGGACGCATTTGCCGC
AATGGCCTGCACGGAGATGCTGACAAGAAACACCCTGAAGCCCAGTCCCCAGGCGTGGCTACAGTTGGTGAAGAATCTTTCCATGCCGCT
GGAGCTCATCTGCTCCGATGAGCACATGCAAGGCAGCGGGAGCCTGGCCCAGGCTGTCATCAGGGAAGTCAGAGCCCAGTGGAGTCGGAT
TTTCTCCACCGCACTCTTCGTGGAGCACGTGCTCCTAGGAACCGAGAGCCGCGTCCCCGAGTTACAGGGGCTGGTGACCGAGCACGTCTT
CTTACTAGACAAGTGTCTTCGAGAGAACTCTGACGTGAAGACGCACGGGCCTTTTGAGGCCGTGATGCGCACTCTCTGTGAATGCAAGGA
GACAGCCAGCAAGACCCTCAGCAGGTTTGGGATTCAGCCGTGCTCCATCTGCCTGGGAGATGCAAAGGACCCCGTCTGTCTGCCCTGCGA
CCACGTGCACTGCCTGCGCTGCCTCAGGGCCTGGTTTGCCTCAGAGCAGATGATATGCCCCTACTGTTTAACTGCCTTGCCAGACGAATT
CTCTCCAGCTGTTTCCCAAGCGCACAGGGAAGCCATTGAAAAGCATGCCCGCTTCCGGCAGATGTGCAACAGTTTCTTCGTAGACCTGGT
GTCCACCATTTGCTTCAAGGACAACGCTCCGCCTGAGAAGGAAGTGATTGAGAGCCTGCTCTCTCTCCTCTTCGTCCAAAAGGGGCGCTT
AAGAGATGCTGCCCAGAGACACTGTGAACACACAAAATCTCTCTCTCCATTCAATGATGTTGTGGATAAGACTCCTGTCATCCGCTCAGT
GATACTGAAACTGCTTTTGAAGTACAGCTTTCATGATGTAAAAGATTATATTCAGGAATATTTGACCCTGTTAAAAAAGAAAGCATTCAT
AACTGAAGATAAAACTGAACTGTACATGCTCTTCATCAACTGCCTGGAGGATTCAATACTTGAGAAGACCAGTGCTTACTCCAGAAATGA
TGAACTGAACCACCTAGAAGAGGAAGGTCGTTTCCTTAAGGCATATTCTCCAGCAAGCCGGGGCCGAGAGCCTGCCAACGAGGCCTCGGT
TGAATACCTGCAAGAGGTGGCCCGGATCCGCCTCTGCCTCGACAGAGCTGCAGATTTCCTCTCGGAGCCTGAGGGAGGCCCAGAGATGGC
CAAGGAGAAGCAGTGCTACCTGCAGCAAGTCAAGCAGTTCTGTATCCGGGTGGAGAACGACTGGCACCGGGTGTACCTGGTGCGGAAGCT
CAGCAGCCAGCGGGGGATGGAGTTCGTGCAGGGCCTCTCCAAGCCCGGCCGCCCGCACCAGTGGGTGTTTCCCAAGGACGTTGTCAAGCA
GCAGGGGCTGCGGCAGGACCACCCAGGCCAGATGGATAGGTACCTGGTGTACGGCGATGAATACAAGGCTCTCCGTGATGCTGTGGCCAA
AGCTGTCCTCGAGTGCAAGCCACTGGGCATTAAGACTGCTCTGAAGGCCTGCAAGACCCCCCAAAGCCAGCAGTCAGCCTACTTCCTGTT
AACACTGTTTAGAGAGGTGGCTATTTTGTACAGATCCCACAATGCAAGCCTCCACCCCACGCCAGAGCAATGTGAAGCTGTGAGCAAATT
CATTGGCGAATGCAAGATCCTTTCACCTCCTGATATCAGCCGTTTTGCAACATCGCTCGTGGACAATTCTGTGCCATTGTTGAGGGCGGG
GCCTAGTGACAGCAACCTTGATGGAACGGTGACAGAAATGGCCATTCATGCTGCAGCCGTCCTTCTGTGTGGACAGAATGAACTCTTGGA
GCCCCTAAAGAATCTGGCCTTCTCCCCAGCCACCATGGCGCATGCTTTTCTTCCAACCATGCCTGAAGACTTGCTGGCTCAAGCTCGGAG
GTGGAAGGGTCTGGAGCGAGTCCACTGGTACACTTGTCCCAACGGCCATCCTTGCTCCGTGGGAGAGTGTGGCAGGCCGATGGAACAGAG
CATCTGCATTGACTGCCATGCGCCGATTGGAGGCATTGACCACAAACCTCGGGACGGCTTTCATCTGGTCAAAGACAAGGCAGACAGAAC
GCAGACCGGCCACGTGCTGGGCAACCCGCAGCGGAGAGACGTGGTGACATGTGACCGAGGGCTGCCCCCAGTGGTCTTCCTCCTTATCCG
GCTACTCACTCACTTGGCTCTGCTTCTGGGAGCGTCCCAGAGTTCCCAGATCAGTCGCATCGAATACATTCATTCAAAGAACTTCATCCA
CCGGGATGTGAAGCCAGACAACTTCCTCATGGGCCTGGGGAAGAAGGGCAACCTGGTGTACATCATCGACTTCGGGCTGGCCAAGAAGTA
CCGGGATGCACGCACCCACCAGCACATCCCCTATCGTGAGAACAAGAACCTCACGGGGACGGCGCGGTACGCCTCCATCAACACGCACCT
TGGAATTGAACAATCCCGAAGAGATGACTTGGAGTCTCTGGGCTACGTGCTAATGTACTTCAACCTGGGCTCTCTCCCCTGGCAGGGGCT
GAAGGCTGCCACCAAGAGACAGAAATACGAAAGGATTAGCGAGAAGAAAATGTCCACCCCCATCGAAGTGTTGTGTAAAGGCTACCCTTC
CGAATTTGCCACATACCTGAATTTCTGCCGTTCCTTGCGTTTTGACGACAAGCCTGACTACTCGTACCTGCGGCAGCTTTTCCGGAATCT
GTTCCATCGCCAGGGCTTCTCCTATGACTACGTGTTCGACTGGAACATGCTCAAATTTGGTGCCAGCCGGGCCGCCGATGACGCCGAGCG
GGAGCGCAGGGACCGAGAGGAGCGGCTGAGACACTCGCGGAACCCGGCTACCCGCGGCCTCCCTTCCACAGCCTCCGGCCGCCTGCGGGG
GACGCAGGAAGTGGCTCCCCCCACACCCCTCACCCCTACCTCACACACGGCTAACACCTCCCCCCGGCCCGTCTCCGGCATGGAGAGAGA
GCGGAAAGTGAGTATGCGGCTGCACCGCGGGGCCCCCGTCAACATCTCCTCGTCCGACCTCACAGGCCGACAAGATACCTCTCGCATGTC
CACCTCACAGATTCCTGGTCGGGTGGCTTCCAGTGGTCTTCAGTCTGTCGTGCACCGATGAGAACTCTCCTTATTGCTGTGAAGGGCAGA
CAATGCATGGCTGATCTACTCTGTTACCAATGGCTTTACTAGTGACACGTCCCCCGGTCTAGGATCGAAATGTTAACACCGGGAGCTCTC
CAGGCCACTCACCCAGCGACGCTCGTGGGGGAAACATACTAAACGGACAGACTCCAAGAGCTGCCACCGCTGGGGCTGCACTGCGGCCCC
CCACGTGAACTCGGTTGTAACGGGGCTGGGAAGAAAAGCAGAGAGAGAATTGCAGAGAATCAGACTCCTTTTCCAGGGCCTCAGCTCCCT
CCAGTGGTGGCCGCCCTGTACTCCCTGACGATTCCACTGTAACTACCAATCTTCTACTTGGTTAAGACAGTTTTGTATCATTTTGCTAAA
AATTATTGGCTTAAATCTGTGTAAAGAAAATCTGTCTTTTTATTGTTTCTTGTCTGTTTTTGCAGTCTTACAAAAAAAATGTTGACTAAG
GAATTCTGAGACAGGCTGGCTTGGAGTTAGTGTATGAGGTGGAGTCGGGCAGGGAGAAGGTGCAGGTGGATCTCAAGGGTGTGTGCTGTG
TTTGTTTTGCAGTGTTTTATTGTCCGCTTTGGAGAGGAGATTTCTCATCAAAAGTCCGTGGTGTGTGTGTGTGCCCGTGTGTGGTGGGAC
CTCTTCAACCTGATTTTGGCGTCTCACCCTCCCTCCTCCCGTAATTGACATGCCTGCTGTCAGGAACTCTTGAGGCCCTCGGAGAGCAGT
TAGGGACCGCAGGCTGCCGCGGGGCAGGGGTGCAGTGGGTGTTACCAGGCAAAGCACTGCGCGCTTCTTCCCCAGGAGGTGGGCAGGCAG
CTGAGAGCTTGGAAGCAGAGGCTTTGAGACCCTAGCAGGACAATTGGGAGTCCCAGGATTCAAGGTGGAAGATGCGTTTCTGGTCCCTTG
GGAGAGGACTGTGAACCGAGAGGTGGTTACTGTAGTGTTTGTTGCCTTGCTGCCTTTGCACTCAGTCCATTTTCTCAGCACTCAATGCTC
CTGTGCGGATTGGCACTCCGTCTGTATGAATGCCTGTGCTTAAAACCAGGAGCGGGGCTGTCCTTGCCACGTGCCAAGACTAGCTCAGAA
AAGCCGGCAGGCCAGAAGGACCCACCCTGAGGTGCCAAGGAGCAGGTGACTCTCCCAACCGGACCCAGAACCTTCACGGCCAGAAAGTAG
AGTCTGCGCTGTGACCTTCTGTTGGGCGCGTGTCTGTTGGTCAGAAGTGAAGCAGCGTGCGTGGGGCCGAGTCCCACCAGAAGGCAGGTG
GCCTCCGTGAGCTGGTGCTGCCCCAGGCTCCATGCTGCTGTGCCCTGAGGTTCCCAGGATGCCTTCTCGCCTCTCACTCCGCAGCACTTG
GGCGGTAGCCAGTGGCCATGTGCTCCCAACCCCAATGCGCAGGGCAGTCTGTGTTCGTGGGCACTTCGGCTGGACCCCATCACGATGGAC
GATGTTCCCTTTGGACTCTAGGGCTTCGAAGGTGTGCACCTTGGTTCTCCCTTCTCCTCCCCAGAGTTCCCCGGATGCCATAACTGGCTG
GCGTCCCAGAACACAGTTGTTCACCCCCCCACCAGCTGGCTGGCCGTCTGCCTGAGCCCATGGATGCTTTCTCAATCCTAGGCTGGTTAC
TGTGTAAGCGTTTTGGAGTACGGGGCCTTGAGCGGGTGGGAGCTGTGTGTTGAAGTACAGAGGGAGGTTGGGGTGGGTCAGAGCCGAGTT
AAGAGATTTTCTTTGTTGCTGGACCCCTTCTTGAAGGTAGACGTCCCCCACCCGGAGAGACGTCGCGCTGTGGCCTGAAGTGGCGCAAGC
TTGCTTTGTAAATATCTGTGGTCCCGATGTAGTGCCCAGAACGTTTGTGCGAGGCAGCTCTGCGCCCGGGTTCCAGCCCGAGCCTCGCCG
GGTCGCGTCTTCGGAGTGCTTGTGACAGTCCTTGCCCAGTATCTAGTCCCCGTCGCCCCGTGCAGGAGACGTAGGTAGGACGTCGTGTCA
GCTGTGCACTGACGGCCAGTCTCCGAGCTGTGCGTTTGTATCGCCACTGTATTTGTGTACTTTAACAATCGTGTAAATAATAAATTCATA

>74967_74967_4_RNF213-CSNK1D_RNF213_chr17_78354787_ENST00000508628_CSNK1D_chr17_80211120_ENST00000314028_length(amino acids)=4951AA_BP=4646
MECPSCQHVSKEETPKFCSQCGERLPPAAPIADSENNNSTMASASEGEMECGQELKEEGGPCLFPGSDSWQENPEEPCSKASWTVQEGAT
SEVLVDAAVDLISDEWEAANAIPSKRRKQDAAPLEAASVPSADCEQSKKKKRKKKKKGNKSASSELASLPLSPASPCHLTLLSNPWPQDT
ALPHSQAQQSGPTGQPSQPPGTATTPLEGDGLSAPTEVGDSPLQAQALGEAGVATGSEAQSSPQFQDHTEGEDQDASIPSGGRGLSQEGT
GPPTSAGEGHSRTEDAAQELLLPESKGGSSEPGTELQTTEQQAGASASMAVDAVAEPANAVKGAGKEMKEKTQRMKQPPATTPPFKTHCQ
EAETKTKDEMAAAEEKVGKNEQGEPEDLKKPEGKNRSAAAVKNEKEQKNQEADVQEVKASTLSPGGGVTVFFHAIISLHFPFNPDLHKVF
IRGGEEFGESKWDSNICELHYTRDLGHDRVLVEGIVCISKKHLDKYIPYKYVIYNGESFEYEFIYKHQQKKGEYVNRCLFIKSSLLGSGD
WHQYYDIVYMKPHGRLQKVMNHITDGPRKDLVKGKQIAAALMLDSTFSILQTWDTINLNSFFTQFEQFCFVLQQPMIYEGQAQLWTDLQY
REKEVKRYLWQHLKKHVVPLPDGKSTDFLPVDCPVRSKLKTGLIVLFVVEKIELLLEGSLDWLCHLLTSDASSPDEFHRDLSHILGIPQS
WRLYLVNLCQRCMDTRTYTWLGALPVLHCCMELAPRHKDAWRQPEDTWAALEGLSFSPFREQMLDTSSLLQFMREKQHLLSIDEPLFRSW
FSLLPLSHLVMYMENFIEHLGRFPAHILDCLSGIYYRLPGLEQVLNTQDVQDVQNVQNILEMLLRLLDTYRDKIPEEALSPSYLTVCLKL
HEAICSSTKLLKFYELPALSAEIVCRMIRLLSLVDSAGQRDETGNNSVQTVFQGTLAATKRWLREVFTKNMLTSSGASFTYVKEIEVWRR
LVEIQFPAEHGWKESLLGDMEWRLTKEEPLSQITAYCNSCWDTKGLEDSVAKTFEKCIIEAVSSACQSQTSILQGFSYSDLRKFGIVLSA
VITKSWPRTADNFNDILKHLLTLADVKHVFRLCGTDEKILANVTEDAKRLIAVADSVLTKVVGDLLSGTILVGQLELIIKHKNQFLDIWQ
LREKSLSPQDEQCAVEEALDWRREELLLLKKEKRCVDSLLKMCGNVKHLIQVDFGVLAVRHSQDLSSKRLNDTVTVRLSTSSNSQRATHY
HLSSQVQEMAGKIDLLRDSHIFQLFWREAAEPLSEPKEDQEAAELLSEPEEESERHILELEEVYDYLYQPSYRKFIKLHQDLKSGEVTLA
EIDVIFKDFVNKYTDLDSELKIMCTVDHQDQRDWIKDRVEQIKEYHHLHQAVHAAKVILQVKESLGLNGDFSVLNTLLNFTDNFDDFRRE
TLDQINQELIQAKKLLQDISEARCKGLQALSLRKEFICWVREALGGINELKVFVDLASISAGENDIDVDRVACFHDAVQGYASLLFKLDP
SVDFSAFMKHLKKLWKALDKDQYLPRKLCDSARNLEWLKTVNESHGSVERSSLTLATAINQRGIYVIQAPKGGQKISPDTVLHLILPESP
GSHEESREYSLEEVKELLNKLMLMSGKKDRNNTEVERFSEVFCSVQRLSQAFIDLHSAGNMLFRTWIAMAYCSPKQGVSLQMDFGLDLVT
ELKEGGDVTELLAALCRQMEHFLDSWKRFVTQKRMEHFYLNFYTAEQLVYLSTELRKQPPSDAALTMLSFIKSNCTLRDVLRASVGCGSE
AARYRMRRVMEELPLMLLSEFSLVDKLRIIMEQSMRCLPAFLPDCLDLETLGHCLAHLAGMGGSPVERCLPRGLQVGQPNLVVCGHSEVL
PAALAVYMQTPSQPLPTYDEVLLCTPATTFEEVALLLRRCLTLGSLGHKVYSLLFADQLSYEVARQAEELFHNLCTQQHREDYQLVMVCD
GDWEHCYLPSAFSQHKVFVTPQAPLEAIQAYLAGHYRVPKQTLSAAAVFNDRLCVGIVASERAGVGKSLYVKRLHDKMKMQLNVKNVPLK
TIRLIDPQVDESRVLGALLPFLDAQYQKVPVLFHLDVTSSVQTGIWVFLFKLLILQYLMDINGKMWLRNPCHLYIVEILERRTSVPSRSS
SALRTRVPQFSFLDIFPKVTCRPPKEVIDMELSALRSDTEPGMDLWEFCSETFQRPYQYLRRFNQNQDLDTFQYQEGSVEGTPEECLQHF
LFHCGVINPSWSELRNFARFLNYQLRDCEASLFCNPSFIGDTLRGFKKFVVTFMIFMARDFATPSLHTSDQSPGKHMVTMDGVREEDLAP
FSLRKRWESEPHPYVFFNDDHTTMTFIGFHLQPNINGSVDAISHLTGKVIKRDVMTRDLYQGLLLQRVPFNVDFDKLPRHKKLERLCLTL
GIPQATDPDKTYELTTDNMLKILAIEMRFRCGIPVIIMGETGCGKTRLIKFLSDLRRGGTNADTIKLVKVHGGTTADMIYSRVREAENVA
FANKDQHQLDTILFFDEANTTEAISCIKEVLCDHMVDGQPLAEDSGLHIIAACNPYRKHSEEMICRLESAGLGYRVSMEETADRLGSIPL
RQLVYRVHALPPSLIPLVWDFGQLSDVAEKLYIQQIVQRLVESISLDENGTRVITEVLCASQGFMRKTEDECSFVSLRDVERCVKVFRWF
HEHSAMLLAQLNAFLSKSSVSKNHTERDPVLWSLMLAIGVCYHASLEKKDSYRKAIARFFPKPYDDSRLLLDEITRAQDLFLDGVPLRKT
IAKNLALKENVFMMVVCIELKIPLFLVGKPGSSKSLAKTIVADAMQGPAAYSDLFRSLKQVHLVSFQCSPHSTPQGIISTFRQCARFQQG
KDLQQYVSVVVLDEVGLAEDSPKMPLKTLHPLLEDGCIEDDPAPHKKVGFVGISNWALDPAKMNRGIFVSRGSPNETELIESAKGICSSD
ILVQDRVQGYFASFAKAYETVCKRQDKEFFGLRDYYSLIKMVFAAAKASNRKPSPQDIAQAVLRNFSGKDDIQALDIFLANLPEAKCSEE
VSPMQLIKQNIFGPSQKVPGGEQEDAESRYLLVLTKNYVALQILQQTFFEGDQQPEIIFGSGFPKDQEYTQLCRNINRVKICMETGKMVL
LLNLQNLYESLYDALNQYYVHLGGQKYVDLGLGTHRVKCRVHPNFRLIVIEEKDVVYKHFPIPLINRLEKHYLDINTVLEKWQKSIVEEL
CAWVEKFINVKAHHFQKRHKYSPSDVFIGYHSDACASVVLQVIERQGPRALTEELHQKVSEEAKSILLNCATPDAVVRLSAYSLGGFAAE
WLSQEYFHRQRHNSFADFLQAHLHTADLERHAIFTEITTFSRLLTSHDCEILESEVTGRAPKPTLLWLQQFDTEYSFLKEVRNCLTNTAK
CKILIFQTDFEDGIRSAQLIASAKYSVINEINKIRENEDRIFVYFITKLSRVGRGTAYVGFHGGLWQSVHIDDLRRSTLMVSDVTRLQHV
TISQLFAPGDLPELGLEHRAEDGHEEAMETEASTSGEVAEVAEEAMETESSEKVGKETSELGGSDVSILDTTRLLRSCVQSAVGMLRDQN
ESCTRNMRRVVLLLGLLNEDDACHASFLRVSKMRLSVFLKKQEESQFHPLEWLAREACNQDALQEAGTFRHTLWKRVQGAVTPLLASMIS
FIDRDGNLELLTRPDTPPWARDLWMFIFSDTMLLNIPLVMNNERHKGEMAYIVVQNHMNLSENASNNVPFSWKIKDYLEELWVQAQYITD
AEGLPKKFVDIFQQTPLGRFLAQLHGEPQQELLQCYLKDFILLTMRVSTEEELKFLQMALWSCTRKLKAASEAPEEEVSLPWVHLAYQRF
RSRLQNFSRILTIYPQVLHSLMEARWNHELAGCEMTLDAFAAMACTEMLTRNTLKPSPQAWLQLVKNLSMPLELICSDEHMQGSGSLAQA
VIREVRAQWSRIFSTALFVEHVLLGTESRVPELQGLVTEHVFLLDKCLRENSDVKTHGPFEAVMRTLCECKETASKTLSRFGIQPCSICL
GDAKDPVCLPCDHVHCLRCLRAWFASEQMICPYCLTALPDEFSPAVSQAHREAIEKHARFRQMCNSFFVDLVSTICFKDNAPPEKEVIES
LLSLLFVQKGRLRDAAQRHCEHTKSLSPFNDVVDKTPVIRSVILKLLLKYSFHDVKDYIQEYLTLLKKKAFITEDKTELYMLFINCLEDS
ILEKTSAYSRNDELNHLEEEGRFLKAYSPASRGREPANEASVEYLQEVARIRLCLDRAADFLSEPEGGPEMAKEKQCYLQQVKQFCIRVE
NDWHRVYLVRKLSSQRGMEFVQGLSKPGRPHQWVFPKDVVKQQGLRQDHPGQMDRYLVYGDEYKALRDAVAKAVLECKPLGIKTALKACK
TPQSQQSAYFLLTLFREVAILYRSHNASLHPTPEQCEAVSKFIGECKILSPPDISRFATSLVDNSVPLLRAGPSDSNLDGTVTEMAIHAA
AVLLCGQNELLEPLKNLAFSPATMAHAFLPTMPEDLLAQARRWKGLERVHWYTCPNGHPCSVGECGRPMEQSICIDCHAPIGGIDHKPRD
GFHLVKDKADRTQTGHVLGNPQRRDVVTCDRGLPPVVFLLIRLLTHLALLLGASQSSQISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNL
VYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMS
TPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGASRAADDAERERRDREERLRHSRNPATR
GLPSTASGRLRGTQEVAPPTPLTPTSHTANTSPRPVSGMERERKVSMRLHRGAPVNISSSDLTGRQDTSRMSTSQIPGRVASSGLQSVVH

--------------------------------------------------------------
>74967_74967_5_RNF213-CSNK1D_RNF213_chr17_78354787_ENST00000508628_CSNK1D_chr17_80211120_ENST00000392334_length(transcript)=15484nt_BP=14089nt
GACAGCGCGCGGCAGGCGGCGAGCTCGGGGGCCGCAGAAAATGAAACTGAAGCCGTGGTCACGTGACAGGACATGTAGTATATAGCAGGC
TGCCAGCGACTCCTGCTCTTGCTTCTGGATCTGCAGGGCAGTCCCAGCAGGACCCATGGAGTGTCCTTCGTGCCAGCATGTCTCCAAGGA
GGAAACCCCCAAGTTCTGCAGCCAGTGCGGAGAGAGGCTGCCTCCTGCAGCCCCCATAGCAGATTCTGAGAACAATAACTCCACAATGGC
GTCGGCCTCGGAGGGTGAAATGGAGTGTGGGCAGGAGCTGAAGGAGGAAGGGGGCCCGTGCTTGTTCCCGGGCTCAGACAGTTGGCAAGA
AAACCCCGAGGAGCCCTGTTCCAAAGCCTCCTGGACCGTCCAAGAAGGAGCTACATCAGAGGTTTTGGTAGATGCTGCTGTAGACCTCAT
ATCCGATGAATGGGAAGCTGCTAATGCCATACCCAGCAAGAGAAGGAAGCAGGATGCAGCCCCGCTTGAGGCCGCCAGCGTGCCTTCTGC
AGACTGTGAGCAGAGCAAAAAGAAGAAAAGGAAGAAGAAAAAGAAGGGGAACAAGTCCGCTTCCTCAGAGCTGGCTTCCTTGCCCCTTTC
TCCTGCCAGCCCCTGTCACCTGACTTTGCTTTCAAACCCGTGGCCTCAGGACACAGCCCTGCCCCACAGCCAAGCCCAGCAGAGTGGCCC
CACTGGCCAGCCGAGCCAGCCCCCAGGCACAGCCACCACGCCACTGGAGGGTGACGGCCTCTCCGCGCCCACCGAGGTTGGCGACAGCCC
CCTGCAGGCCCAGGCTTTGGGAGAGGCAGGAGTGGCCACAGGAAGTGAGGCTCAGAGCAGCCCGCAATTCCAGGACCACACGGAAGGGGA
GGACCAGGACGCTTCCATCCCCTCTGGGGGCAGAGGCCTGTCCCAGGAGGGGACCGGTCCCCCCACCTCTGCTGGTGAAGGCCATTCTAG
GACTGAAGATGCTGCCCAGGAGCTCCTGTTGCCTGAGTCAAAAGGAGGCAGCTCTGAGCCCGGGACAGAACTGCAGACCACCGAGCAACA
GGCAGGGGCCTCAGCCTCTATGGCAGTTGATGCTGTAGCTGAGCCAGCCAATGCAGTTAAAGGGGCCGGGAAGGAAATGAAAGAGAAGAC
CCAGAGAATGAAACAGCCACCAGCAACCACTCCTCCTTTCAAAACACACTGCCAGGAAGCTGAGACCAAGACCAAGGACGAGATGGCTGC
TGCTGAAGAAAAAGTCGGTAAGAATGAACAAGGGGAGCCTGAAGACCTCAAGAAGCCAGAGGGGAAGAACAGAAGTGCAGCTGCTGTGAA
AAACGAGAAGGAGCAAAAAAACCAGGAAGCAGATGTCCAGGAAGTGAAGGCAAGCACGCTGAGCCCGGGTGGAGGAGTCACCGTGTTCTT
CCACGCCATCATCTCTCTTCATTTCCCATTCAATCCTGACCTCCATAAAGTCTTCATCAGAGGAGGAGAAGAATTTGGGGAGTCAAAATG
GGACAGCAATATCTGTGAGCTGCACTACACCAGAGACTTGGGTCATGACCGCGTTCTTGTTGAAGGCATTGTCTGCATTTCCAAGAAGCA
CCTAGATAAATACATTCCTTACAAGTACGTCATTTATAATGGGGAATCTTTTGAGTATGAGTTCATTTACAAGCACCAGCAGAAGAAGGG
CGAGTACGTCAACCGCTGTCTGTTCATAAAATCTTCACTTCTGGGCTCAGGAGACTGGCATCAGTACTATGACATAGTTTATATGAAGCC
TCATGGGAGACTCCAGAAAGTCATGAACCACATCACAGACGGGCCGAGGAAGGACCTGGTGAAGGGGAAGCAGATTGCCGCTGCGCTCAT
GCTGGACAGCACCTTCAGCATCCTGCAGACCTGGGACACCATCAACCTGAACAGCTTCTTCACCCAGTTCGAGCAGTTTTGCTTTGTCCT
GCAACAGCCTATGATTTATGAAGGACAGGCACAGCTGTGGACCGATTTGCAGTACAGGGAGAAAGAGGTGAAGAGATACCTGTGGCAACA
TCTGAAAAAACACGTGGTACCATTGCCGGACGGAAAAAGCACGGACTTTTTGCCTGTGGACTGCCCAGTGAGGAGTAAACTGAAAACAGG
CCTGATTGTCCTTTTTGTAGTGGAAAAAATTGAGCTTTTATTAGAAGGCAGCCTGGACTGGTTGTGTCACCTCCTAACCTCAGATGCCAG
CTCACCAGATGAGTTTCACCGTGACCTAAGCCACATCCTTGGGATACCTCAGAGCTGGCGGCTGTACCTGGTGAACCTGTGCCAAAGATG
CATGGACACAAGGACGTACACCTGGCTGGGCGCCCTGCCTGTCCTGCACTGCTGTATGGAGCTGGCCCCGCGGCACAAGGATGCCTGGAG
ACAGCCTGAGGACACCTGGGCCGCTCTGGAGGGACTCTCCTTCTCACCGTTCCGGGAACAAATGCTAGATACGAGTTCCCTACTTCAGTT
TATGAGAGAGAAGCAGCATTTGCTGAGCATAGACGAGCCTCTCTTCCGGTCCTGGTTTAGTCTGCTACCTCTGAGTCACCTGGTTATGTA
TATGGAAAACTTCATTGAGCACCTGGGTCGTTTTCCTGCTCATATCCTGGACTGTCTTTCAGGGATTTACTACCGGCTTCCGGGACTTGA
GCAAGTCTTGAATACGCAGGATGTTCAGGATGTTCAGAACGTTCAGAACATTTTAGAAATGCTGTTGCGACTCCTGGACACTTACCGGGA
CAAGATTCCCGAGGAGGCCTTGTCACCATCCTACCTGACTGTGTGTCTGAAACTGCATGAAGCCATCTGCAGCAGCACAAAGCTACTTAA
GTTTTACGAGCTGCCAGCCTTATCTGCCGAGATTGTCTGCAGAATGATTAGACTTCTATCTCTGGTGGATTCTGCAGGACAGAGAGATGA
AACTGGAAATAATTCAGTCCAAACAGTCTTCCAAGGGACCCTTGCTGCTACGAAAAGGTGGCTCCGAGAAGTTTTTACAAAGAACATGCT
CACATCTTCAGGTGCCTCATTCACATACGTCAAGGAAATTGAGGTCTGGAGGCGGCTGGTGGAAATCCAATTCCCCGCGGAGCATGGCTG
GAAGGAGTCGTTGCTGGGAGACATGGAATGGAGGCTCACAAAGGAGGAACCCCTCTCCCAGATCACTGCCTACTGCAATAGTTGCTGGGA
CACCAAAGGCTTAGAGGACAGTGTGGCCAAGACCTTCGAGAAATGCATCATTGAAGCCGTGAGCTCAGCCTGCCAGTCTCAGACCAGTAT
CCTTCAGGGGTTCTCTTACTCTGATTTGCGGAAATTTGGCATCGTCTTGTCTGCTGTGATCACTAAGTCCTGGCCTAGGACCGCGGACAA
CTTCAATGACATTTTAAAGCATCTGCTCACGTTGGCAGATGTCAAGCACGTCTTCAGATTGTGTGGAACCGACGAGAAAATACTAGCAAA
TGTCACAGAGGATGCCAAGAGGCTGATAGCTGTTGCCGACTCTGTGTTGACGAAAGTTGTTGGTGACCTCCTAAGTGGCACGATTTTAGT
TGGACAACTGGAGCTGATTATAAAGCACAAGAATCAGTTTCTTGACATCTGGCAACTGAGGGAAAAAAGTCTTTCACCCCAGGATGAACA
ATGTGCTGTGGAGGAAGCACTGGATTGGAGAAGGGAGGAACTGTTACTTCTAAAGAAAGAGAAAAGATGTGTTGATAGTCTCCTGAAGAT
GTGTGGGAACGTGAAACATCTGATACAAGTGGACTTTGGAGTGCTTGCAGTAAGACACTCACAAGACCTCAGCAGTAAAAGATTAAATGA
CACCGTGACAGTGAGACTGTCCACCTCCTCGAACTCGCAGAGGGCAACGCATTACCACCTGAGCTCCCAGGTCCAAGAAATGGCTGGGAA
GATAGACTTGCTCAGAGACAGCCACATCTTCCAGCTCTTCTGGCGGGAAGCCGCAGAGCCGCTGAGTGAGCCTAAGGAGGACCAGGAAGC
CGCAGAGTTGCTGAGTGAGCCCGAAGAAGAATCAGAAAGGCACATCCTTGAGCTTGAAGAGGTGTATGACTATTTGTATCAGCCTTCTTA
CAGAAAGTTCATTAAGTTGCACCAGGATCTAAAGTCAGGAGAGGTCACCCTTGCAGAGATTGATGTCATCTTCAAGGACTTTGTGAATAA
ATACACGGACCTGGATTCAGAACTTAAGATCATGTGCACCGTGGACCACCAGGACCAAAGAGATTGGATCAAGGACCGAGTCGAACAGAT
CAAGGAATACCATCACCTGCACCAGGCTGTCCACGCAGCCAAGGTCATCTTGCAGGTCAAAGAGAGCCTGGGACTGAACGGTGACTTCAG
TGTTCTCAACACTTTACTAAATTTTACTGATAACTTCGACGACTTTCGCCGTGAAACACTGGACCAGATCAACCAGGAGCTCATCCAGGC
CAAAAAGCTGCTCCAGGACATCAGCGAGGCCCGGTGCAAGGGGCTGCAGGCTCTGTCCCTGAGAAAGGAGTTCATCTGCTGGGTCCGGGA
GGCTCTTGGAGGCATCAATGAGCTGAAGGTGTTTGTGGACCTGGCCTCCATCTCAGCGGGGGAGAATGACATTGATGTGGACCGGGTGGC
CTGCTTCCATGACGCTGTGCAGGGCTACGCATCCCTGCTATTTAAGCTGGACCCCAGCGTGGACTTCAGTGCATTCATGAAGCATCTGAA
AAAGCTGTGGAAGGCTCTGGATAAGGACCAGTACCTGCCCAGGAAACTGTGTGACTCCGCCAGGAACTTGGAATGGCTGAAGACTGTGAA
TGAGAGTCATGGGTCTGTGGAACGCTCATCCCTGACCCTGGCCACGGCCATCAACCAAAGAGGCATCTATGTGATCCAGGCGCCCAAAGG
TGGCCAAAAGATTTCCCCAGACACGGTTCTGCACTTGATCCTTCCTGAGAGCCCTGGCAGCCACGAGGAGTCACGAGAGTACTCTTTAGA
GGAGGTGAAGGAGCTTTTGAACAAGTTGATGCTGATGTCTGGCAAGAAGGATCGTAACAACACGGAAGTGGAGAGGTTTTCAGAGGTCTT
CTGCAGTGTGCAGAGGCTCAGCCAGGCCTTCATCGACCTGCACTCTGCTGGGAATATGCTGTTCAGGACGTGGATCGCCATGGCCTACTG
CTCCCCCAAGCAGGGTGTGTCCCTCCAAATGGACTTTGGCTTGGACCTGGTGACGGAGCTTAAAGAAGGTGGAGATGTCACTGAGCTGCT
GGCAGCCCTCTGCAGGCAGATGGAGCACTTCCTTGACAGCTGGAAGAGATTTGTGACCCAGAAGCGAATGGAGCACTTTTACCTGAACTT
CTACACGGCAGAGCAGCTGGTTTACCTGAGCACTGAGCTCAGGAAGCAGCCCCCGAGTGATGCCGCCCTAACGATGCTATCCTTCATCAA
AAGCAACTGCACCCTGAGGGATGTCTTAAGGGCCTCTGTGGGGTGTGGGAGTGAGGCCGCCAGGTACCGCATGAGGAGAGTCATGGAAGA
GCTCCCGCTGATGCTCTTATCAGAGTTCAGCCTGGTGGACAAGCTGAGGATCATCATGGAGCAGTCCATGAGGTGCCTTCCTGCCTTCCT
GCCCGACTGCCTCGACCTAGAGACCCTTGGCCACTGTCTGGCTCACCTGGCAGGGATGGGTGGGTCTCCCGTGGAGCGTTGTCTCCCGAG
AGGTCTGCAGGTCGGCCAGCCCAACCTCGTCGTCTGTGGCCACTCCGAGGTGTTGCCAGCCGCCCTGGCTGTCTACATGCAAACCCCAAG
CCAGCCCCTGCCCACTTACGATGAGGTGCTGCTCTGCACCCCGGCAACCACCTTTGAGGAGGTGGCACTGTTGCTGCGCCGCTGCCTGAC
CCTGGGCTCCCTGGGGCACAAGGTCTACAGCCTGCTGTTCGCAGATCAGCTGAGCTACGAGGTGGCACGCCAAGCGGAGGAGCTTTTCCA
CAATCTGTGCACGCAGCAGCACCGAGAAGACTACCAGCTCGTCATGGTCTGTGATGGGGACTGGGAGCACTGCTACCTCCCCTCTGCCTT
CAGCCAGCACAAGGTCTTCGTCACCCCCCAGGCACCCCTCGAGGCCATCCAAGCCTACCTGGCAGGTCACTACCGGGTCCCGAAGCAGAC
CCTGTCGGCGGCAGCCGTGTTCAATGACCGGCTGTGTGTTGGGATCGTGGCCTCGGAGCGAGCAGGTGTTGGAAAGTCTCTGTACGTGAA
GAGGTTGCACGACAAAATGAAGATGCAGTTAAACGTGAAAAATGTGCCTCTGAAAACAATTCGACTGATCGACCCTCAGGTGGATGAGAG
CCGAGTCCTGGGCGCCCTGCTGCCCTTCCTGGATGCGCAGTATCAGAAGGTCCCCGTGCTCTTTCACCTGGACGTGACCTCCTCAGTGCA
GACTGGAATTTGGGTGTTTCTTTTCAAGCTCCTCATTTTACAATACTTAATGGATATAAATGGGAAAATGTGGCTTCGGAACCCCTGCCA
TTTGTATATCGTTGAAATCCTGGAAAGGAGGACGTCAGTGCCGTCGAGGAGCTCTTCAGCGCTGCGTACACGTGTACCCCAGTTCAGTTT
TCTTGACATCTTCCCAAAAGTCACCTGCAGGCCTCCCAAAGAGGTGATAGACATGGAGCTGAGTGCCCTGAGGAGTGACACAGAGCCTGG
GATGGATCTGTGGGAGTTCTGCAGCGAAACTTTCCAAAGACCTTACCAGTATTTAAGACGATTCAATCAAAACCAAGACCTAGACACGTT
TCAGTATCAAGAAGGCTCTGTCGAAGGCACCCCGGAGGAATGCCTCCAGCATTTCCTGTTTCACTGCGGGGTAATAAACCCATCCTGGTC
AGAGCTTCGGAACTTTGCTCGGTTCCTGAATTATCAGCTCAGAGATTGTGAGGCCTCTCTCTTCTGCAATCCGAGTTTTATTGGCGACAC
ACTGAGGGGCTTCAAGAAGTTCGTGGTGACCTTCATGATCTTTATGGCAAGAGATTTTGCCACACCATCACTCCACACCTCTGACCAAAG
CCCGGGGAAGCACATGGTCACCATGGATGGGGTTAGGGAAGAAGATCTAGCGCCCTTCTCCCTCCGGAAGAGGTGGGAGTCGGAGCCTCA
CCCATACGTTTTCTTCAATGACGACCACACAACCATGACATTCATCGGCTTCCATCTGCAGCCCAACATCAACGGCAGTGTCGATGCCAT
CAGTCACTTGACTGGGAAGGTCATCAAGAGAGACGTCATGACCAGGGACCTGTACCAGGGCCTGCTGCTCCAGAGGGTGCCCTTCAATGT
CGACTTTGATAAACTGCCCAGACACAAGAAACTTGAGAGGCTCTGCCTGACCTTAGGGATCCCCCAGGCCACCGACCCCGACAAAACGTA
TGAGCTCACAACCGACAATATGCTTAAAATCCTTGCCATCGAGATGCGGTTCCGGTGTGGGATCCCGGTTATCATCATGGGAGAAACTGG
CTGTGGGAAAACCAGGCTTATTAAATTCCTTAGCGACCTGCGGCGTGGTGGTACCAATGCTGACACCATAAAGCTGGTCAAGGTGCACGG
AGGAACAACTGCAGACATGATCTACTCCAGAGTCAGGGAGGCTGAAAATGTGGCCTTCGCCAATAAGGACCAACATCAGTTGGACACCAT
CTTGTTTTTTGATGAAGCCAACACAACGGAAGCTATAAGCTGTATCAAAGAAGTCCTGTGTGATCATATGGTGGATGGCCAGCCTCTGGC
TGAGGACTCTGGCCTGCATATTATAGCTGCCTGCAATCCATACCGGAAGCACTCTGAGGAGATGATCTGCCGTTTGGAGTCAGCTGGTTT
GGGCTACAGGGTTAGTATGGAGGAGACGGCCGACAGGCTGGGCTCCATTCCTCTGAGGCAGCTGGTATACCGGGTCCATGCTCTGCCCCC
GAGCCTGATTCCTCTGGTGTGGGACTTTGGACAACTGAGTGACGTTGCTGAAAAGCTCTACATCCAGCAGATTGTCCAGAGACTGGTTGA
GTCCATCAGCCTAGATGAAAACGGGACTCGCGTGATCACAGAAGTCCTCTGCGCCTCTCAGGGTTTCATGAGGAAAACAGAAGATGAGTG
CAGCTTTGTCAGCCTCAGGGACGTGGAGCGCTGTGTGAAAGTTTTCAGGTGGTTCCACGAGCACAGCGCGATGCTCTTAGCGCAGCTGAA
TGCCTTTCTCTCCAAGTCCAGCGTCAGCAAAAATCACACCGAGAGAGATCCCGTCCTCTGGTCGTTGATGCTGGCCATCGGGGTGTGTTA
CCATGCCTCTTTAGAAAAGAAAGACTCATATCGGAAAGCCATCGCCAGGTTCTTTCCGAAACCGTATGACGACAGCAGGCTGCTTCTGGA
TGAAATAACACGGGCACAGGATCTTTTTCTGGACGGCGTACCTCTGAGGAAAACCATCGCCAAGAACTTGGCCTTGAAGGAGAACGTCTT
CATGATGGTCGTCTGCATCGAGCTGAAGATTCCCCTCTTCCTGGTGGGGAAGCCCGGCAGCTCCAAGTCTCTCGCCAAGACCATCGTGGC
AGACGCCATGCAGGGCCCGGCTGCCTACTCAGATCTCTTCCGCAGCCTGAAGCAGGTCCACCTGGTGTCCTTCCAGTGCAGCCCGCACTC
CACCCCACAGGGCATCATCAGCACCTTCCGGCAGTGCGCCCGCTTTCAGCAGGGGAAGGACCTGCAGCAGTACGTCTCTGTGGTGGTGTT
AGATGAGGTGGGGCTGGCGGAAGACTCACCCAAAATGCCCCTGAAGACTCTGCACCCGCTGCTGGAAGACGGATGCATTGAAGACGATCC
CGCCCCCCACAAAAAGGTCGGCTTCGTGGGCATCTCCAACTGGGCCCTTGACCCTGCCAAGATGAACCGGGGCATTTTTGTGTCACGTGG
CAGCCCCAACGAGACAGAGCTCATAGAGAGCGCCAAGGGCATCTGCTCCTCAGACATCCTCGTCCAGGACCGAGTCCAAGGGTACTTTGC
GTCCTTTGCCAAAGCCTACGAAACGGTGTGTAAGCGCCAGGACAAGGAATTCTTCGGGCTTCGTGACTACTACAGCCTCATCAAAATGGT
CTTTGCTGCAGCAAAGGCTTCAAATAGAAAGCCTTCCCCGCAAGACATTGCACAGGCTGTCCTTAGGAACTTCAGTGGCAAGGATGACAT
CCAAGCTTTGGACATCTTTCTGGCCAATTTGCCCGAGGCCAAGTGCTCAGAGGAAGTCAGCCCCATGCAGCTGATCAAACAGAACATCTT
TGGGCCTTCTCAGAAGGTGCCGGGTGGAGAGCAGGAAGATGCTGAGTCCCGCTACTTACTCGTGCTGACCAAAAACTACGTGGCACTGCA
GATCCTGCAGCAGACATTCTTCGAGGGGGACCAGCAGCCGGAGATTATTTTTGGTTCTGGTTTCCCCAAGGACCAAGAGTACACCCAGCT
CTGCAGAAACATCAATCGTGTGAAGATCTGCATGGAAACAGGCAAGATGGTGTTGCTTCTCAACCTGCAGAACCTCTACGAGAGCCTCTA
CGACGCACTCAACCAGTACTACGTCCACCTCGGCGGCCAGAAGTACGTGGACCTCGGTCTGGGGACCCACCGCGTCAAATGTCGGGTTCA
CCCCAACTTCCGCCTGATTGTCATTGAAGAGAAAGACGTCGTGTACAAACACTTTCCCATCCCCCTCATTAACCGGCTGGAGAAGCACTA
TCTGGATATCAACACGGTGCTGGAGAAATGGCAGAAGAGCATCGTGGAGGAGCTCTGTGCGTGGGTGGAGAAGTTCATCAATGTCAAAGC
ACATCATTTCCAGAAGAGGCACAAATACAGCCCCTCTGACGTCTTCATCGGCTACCACTCGGACGCCTGCGCGTCTGTGGTGCTGCAGGT
CATAGAGAGGCAGGGTCCCCGGGCCTTGACGGAGGAACTTCACCAGAAGGTGTCTGAGGAGGCCAAATCGATCCTGCTGAACTGCGCTAC
GCCCGATGCCGTGGTCCGGCTGAGCGCCTACTCGCTGGGCGGGTTCGCAGCGGAGTGGCTGTCGCAGGAGTACTTTCACAGACAGAGGCA
CAACTCCTTTGCAGATTTCCTTCAGGCACACCTGCACACGGCAGACCTGGAGCGCCACGCCATCTTCACAGAGATCACCACTTTCTCCAG
GCTGCTAACAAGTCACGACTGTGAAATTTTAGAATCAGAGGTCACAGGCAGGGCTCCGAAACCCACACTCCTGTGGCTGCAGCAGTTTGA
CACCGAGTACTCATTCCTCAAAGAAGTCCGAAACTGTTTAACGAATACAGCCAAATGTAAAATCCTCATTTTTCAGACAGATTTTGAAGA
TGGAATCCGTAGCGCCCAGCTCATTGCCTCAGCTAAGTATTCTGTTATAAATGAAATCAACAAAATACGAGAAAATGAGGACCGTATCTT
CGTCTATTTCATCACAAAACTGTCCCGGGTGGGAAGAGGAACAGCCTATGTGGGCTTCCACGGAGGGCTGTGGCAGTCTGTCCACATCGA
TGACCTCCGGAGATCCACCCTCATGGTTTCTGATGTGACCAGGCTGCAGCATGTCACCATCAGCCAGCTGTTCGCGCCCGGAGACTTGCC
TGAGCTGGGCTTGGAACACCGGGCGGAAGACGGCCATGAGGAGGCGATGGAGACGGAGGCCAGCACATCAGGGGAGGTGGCAGAGGTGGC
AGAGGAGGCCATGGAAACAGAAAGTTCTGAGAAGGTGGGAAAGGAAACCTCTGAACTCGGAGGCAGTGATGTGTCGATCCTGGACACCAC
CAGGCTGCTGAGAAGCTGTGTGCAGAGCGCCGTGGGCATGCTCAGAGACCAGAACGAGAGCTGCACGCGCAATATGCGGAGGGTGGTGCT
CCTCCTGGGCCTCTTGAATGAGGATGACGCGTGCCACGCCTCTTTCTTGCGGGTATCCAAGATGCGCCTCAGTGTCTTTTTAAAGAAGCA
AGAAGAGAGCCAGTTTCACCCTCTGGAGTGGTTGGCAAGGGAAGCCTGCAACCAGGACGCTCTCCAGGAGGCGGGCACATTCAGGCACAC
CCTCTGGAAGCGGGTCCAAGGTGCTGTCACCCCTCTGCTGGCGAGCATGATATCATTCATCGACAGAGACGGCAACCTAGAGTTACTGAC
CAGGCCAGATACTCCGCCCTGGGCAAGAGATCTTTGGATGTTTATTTTCAGTGACACGATGCTTCTGAACATTCCTCTTGTGATGAATAA
TGAAAGACATAAAGGTGAGATGGCCTACATCGTGGTGCAGAACCACATGAACCTTTCCGAGAACGCTTCCAACAACGTCCCTTTCAGCTG
GAAAATCAAGGACTATCTGGAGGAGCTGTGGGTCCAGGCTCAGTACATCACAGACGCAGAAGGACTGCCCAAGAAGTTCGTGGACATCTT
TCAGCAGACTCCTCTGGGCAGGTTTCTTGCCCAGCTCCATGGAGAGCCGCAGCAGGAACTTCTTCAGTGTTACTTGAAGGATTTCATTCT
CTTGACCATGCGTGTGTCAACGGAGGAGGAATTAAAGTTTCTGCAGATGGCTCTGTGGTCCTGCACTAGGAAACTGAAAGCGGCGTCAGA
AGCGCCCGAGGAAGAGGTTTCCTTACCGTGGGTGCACCTTGCCTACCAGCGTTTCAGAAGCCGTCTGCAGAACTTTTCCAGAATCCTGAC
CATCTACCCTCAGGTTCTCCACAGCCTGATGGAAGCCCGTTGGAACCATGAGCTGGCTGGATGTGAGATGACCCTGGACGCATTTGCCGC
AATGGCCTGCACGGAGATGCTGACAAGAAACACCCTGAAGCCCAGTCCCCAGGCGTGGCTACAGTTGGTGAAGAATCTTTCCATGCCGCT
GGAGCTCATCTGCTCCGATGAGCACATGCAAGGCAGCGGGAGCCTGGCCCAGGCTGTCATCAGGGAAGTCAGAGCCCAGTGGAGTCGGAT
TTTCTCCACCGCACTCTTCGTGGAGCACGTGCTCCTAGGAACCGAGAGCCGCGTCCCCGAGTTACAGGGGCTGGTGACCGAGCACGTCTT
CTTACTAGACAAGTGTCTTCGAGAGAACTCTGACGTGAAGACGCACGGGCCTTTTGAGGCCGTGATGCGCACTCTCTGTGAATGCAAGGA
GACAGCCAGCAAGACCCTCAGCAGGTTTGGGATTCAGCCGTGCTCCATCTGCCTGGGAGATGCAAAGGACCCCGTCTGTCTGCCCTGCGA
CCACGTGCACTGCCTGCGCTGCCTCAGGGCCTGGTTTGCCTCAGAGCAGATGATATGCCCCTACTGTTTAACTGCCTTGCCAGACGAATT
CTCTCCAGCTGTTTCCCAAGCGCACAGGGAAGCCATTGAAAAGCATGCCCGCTTCCGGCAGATGTGCAACAGTTTCTTCGTAGACCTGGT
GTCCACCATTTGCTTCAAGGACAACGCTCCGCCTGAGAAGGAAGTGATTGAGAGCCTGCTCTCTCTCCTCTTCGTCCAAAAGGGGCGCTT
AAGAGATGCTGCCCAGAGACACTGTGAACACACAAAATCTCTCTCTCCATTCAATGATGTTGTGGATAAGACTCCTGTCATCCGCTCAGT
GATACTGAAACTGCTTTTGAAGTACAGCTTTCATGATGTAAAAGATTATATTCAGGAATATTTGACCCTGTTAAAAAAGAAAGCATTCAT
AACTGAAGATAAAACTGAACTGTACATGCTCTTCATCAACTGCCTGGAGGATTCAATACTTGAGAAGACCAGTGCTTACTCCAGAAATGA
TGAACTGAACCACCTAGAAGAGGAAGGTCGTTTCCTTAAGGCATATTCTCCAGCAAGCCGGGGCCGAGAGCCTGCCAACGAGGCCTCGGT
TGAATACCTGCAAGAGGTGGCCCGGATCCGCCTCTGCCTCGACAGAGCTGCAGATTTCCTCTCGGAGCCTGAGGGAGGCCCAGAGATGGC
CAAGGAGAAGCAGTGCTACCTGCAGCAAGTCAAGCAGTTCTGTATCCGGGTGGAGAACGACTGGCACCGGGTGTACCTGGTGCGGAAGCT
CAGCAGCCAGCGGGGGATGGAGTTCGTGCAGGGCCTCTCCAAGCCCGGCCGCCCGCACCAGTGGGTGTTTCCCAAGGACGTTGTCAAGCA
GCAGGGGCTGCGGCAGGACCACCCAGGCCAGATGGATAGGTACCTGGTGTACGGCGATGAATACAAGGCTCTCCGTGATGCTGTGGCCAA
AGCTGTCCTCGAGTGCAAGCCACTGGGCATTAAGACTGCTCTGAAGGCCTGCAAGACCCCCCAAAGCCAGCAGTCAGCCTACTTCCTGTT
AACACTGTTTAGAGAGGTGGCTATTTTGTACAGATCCCACAATGCAAGCCTCCACCCCACGCCAGAGCAATGTGAAGCTGTGAGCAAATT
CATTGGCGAATGCAAGATCCTTTCACCTCCTGATATCAGCCGTTTTGCAACATCGCTCGTGGACAATTCTGTGCCATTGTTGAGGGCGGG
GCCTAGTGACAGCAACCTTGATGGAACGGTGACAGAAATGGCCATTCATGCTGCAGCCGTCCTTCTGTGTGGACAGAATGAACTCTTGGA
GCCCCTAAAGAATCTGGCCTTCTCCCCAGCCACCATGGCGCATGCTTTTCTTCCAACCATGCCTGAAGACTTGCTGGCTCAAGCTCGGAG
GTGGAAGGGTCTGGAGCGAGTCCACTGGTACACTTGTCCCAACGGCCATCCTTGCTCCGTGGGAGAGTGTGGCAGGCCGATGGAACAGAG
CATCTGCATTGACTGCCATGCGCCGATTGGAGGCATTGACCACAAACCTCGGGACGGCTTTCATCTGGTCAAAGACAAGGCAGACAGAAC
GCAGACCGGCCACGTGCTGGGCAACCCGCAGCGGAGAGACGTGGTGACATGTGACCGAGGGCTGCCCCCAGTGGTCTTCCTCCTTATCCG
GCTACTCACTCACTTGGCTCTGCTTCTGGGAGCGTCCCAGAGTTCCCAGATCAGTCGCATCGAATACATTCATTCAAAGAACTTCATCCA
CCGGGATGTGAAGCCAGACAACTTCCTCATGGGCCTGGGGAAGAAGGGCAACCTGGTGTACATCATCGACTTCGGGCTGGCCAAGAAGTA
CCGGGATGCACGCACCCACCAGCACATCCCCTATCGTGAGAACAAGAACCTCACGGGGACGGCGCGGTACGCCTCCATCAACACGCACCT
TGGAATTGAACAATCCCGAAGAGATGACTTGGAGTCTCTGGGCTACGTGCTAATGTACTTCAACCTGGGCTCTCTCCCCTGGCAGGGGCT
GAAGGCTGCCACCAAGAGACAGAAATACGAAAGGATTAGCGAGAAGAAAATGTCCACCCCCATCGAAGTGTTGTGTAAAGGCTACCCTTC
CGAATTTGCCACATACCTGAATTTCTGCCGTTCCTTGCGTTTTGACGACAAGCCTGACTACTCGTACCTGCGGCAGCTTTTCCGGAATCT
GTTCCATCGCCAGGGCTTCTCCTATGACTACGTGTTCGACTGGAACATGCTCAAATTTGGTGCCAGCCGGGCCGCCGATGACGCCGAGCG
GGAGCGCAGGGACCGAGAGGAGCGGCTGAGACACTCGCGGAACCCGGCTACCCGCGGCCTCCCTTCCACAGCCTCCGGCCGCCTGCGGGG
GACGCAGGAAGTGGCTCCCCCCACACCCCTCACCCCTACCTCACACACGGCTAACACCTCCCCCCGGCCCGTCTCCGGCATGGAGAGAGA
GCGGAAAGTGAGTATGCGGCTGCACCGCGGGGCCCCCGTCAACATCTCCTCGTCCGACCTCACAGGCCGACAAGATACCTCTCGCATGTC
CACCTCACAGAATAGCATTCCTTTCGAACACCACGGCAAGTAGCTGCTCGTCTCCCATCGGAAGGCAGCACTGGATTCCTGGTCGGGTGG
CTTCCAGTGGTCTTCAGTCTGTCGTGCACCGATGAGAACTCTCCTTATTGCTGTGAAGGGCAGACAATGCATGGCTGATCTACTCTGTTA
CCAATGGCTTTACTAGTGACACGTCCCCCGGTCTAGGATCGAAATGTTAACACCGGGAGCTCTCCAGGCCACTCACCCAGCGACGCTCGT
GGGGGAAACATACTAAACGGACAGACTCCAAGAGCTGCCACCGCTGGGGCTGCACTGCGGCCCCCCACGTGAACTCGGTTGTAACGGGGC
TGGGAAGAAAAGCAGAGAGAGAATTGCAGAGAATCAGACTCCTTTTCCAGGGCCTCAGCTCCCTCCAGTGGTGGCCGCCCTGTACTCCCT
GACGATTCCACTGTAACTACCAATCTTCTACTTGGTTAAGACAGTTTTGTATCATTTTGCTAAAAATTATTGGCTTAAATCTGTGTAAAG

>74967_74967_5_RNF213-CSNK1D_RNF213_chr17_78354787_ENST00000508628_CSNK1D_chr17_80211120_ENST00000392334_length(amino acids)=4945AA_BP=4646
MECPSCQHVSKEETPKFCSQCGERLPPAAPIADSENNNSTMASASEGEMECGQELKEEGGPCLFPGSDSWQENPEEPCSKASWTVQEGAT
SEVLVDAAVDLISDEWEAANAIPSKRRKQDAAPLEAASVPSADCEQSKKKKRKKKKKGNKSASSELASLPLSPASPCHLTLLSNPWPQDT
ALPHSQAQQSGPTGQPSQPPGTATTPLEGDGLSAPTEVGDSPLQAQALGEAGVATGSEAQSSPQFQDHTEGEDQDASIPSGGRGLSQEGT
GPPTSAGEGHSRTEDAAQELLLPESKGGSSEPGTELQTTEQQAGASASMAVDAVAEPANAVKGAGKEMKEKTQRMKQPPATTPPFKTHCQ
EAETKTKDEMAAAEEKVGKNEQGEPEDLKKPEGKNRSAAAVKNEKEQKNQEADVQEVKASTLSPGGGVTVFFHAIISLHFPFNPDLHKVF
IRGGEEFGESKWDSNICELHYTRDLGHDRVLVEGIVCISKKHLDKYIPYKYVIYNGESFEYEFIYKHQQKKGEYVNRCLFIKSSLLGSGD
WHQYYDIVYMKPHGRLQKVMNHITDGPRKDLVKGKQIAAALMLDSTFSILQTWDTINLNSFFTQFEQFCFVLQQPMIYEGQAQLWTDLQY
REKEVKRYLWQHLKKHVVPLPDGKSTDFLPVDCPVRSKLKTGLIVLFVVEKIELLLEGSLDWLCHLLTSDASSPDEFHRDLSHILGIPQS
WRLYLVNLCQRCMDTRTYTWLGALPVLHCCMELAPRHKDAWRQPEDTWAALEGLSFSPFREQMLDTSSLLQFMREKQHLLSIDEPLFRSW
FSLLPLSHLVMYMENFIEHLGRFPAHILDCLSGIYYRLPGLEQVLNTQDVQDVQNVQNILEMLLRLLDTYRDKIPEEALSPSYLTVCLKL
HEAICSSTKLLKFYELPALSAEIVCRMIRLLSLVDSAGQRDETGNNSVQTVFQGTLAATKRWLREVFTKNMLTSSGASFTYVKEIEVWRR
LVEIQFPAEHGWKESLLGDMEWRLTKEEPLSQITAYCNSCWDTKGLEDSVAKTFEKCIIEAVSSACQSQTSILQGFSYSDLRKFGIVLSA
VITKSWPRTADNFNDILKHLLTLADVKHVFRLCGTDEKILANVTEDAKRLIAVADSVLTKVVGDLLSGTILVGQLELIIKHKNQFLDIWQ
LREKSLSPQDEQCAVEEALDWRREELLLLKKEKRCVDSLLKMCGNVKHLIQVDFGVLAVRHSQDLSSKRLNDTVTVRLSTSSNSQRATHY
HLSSQVQEMAGKIDLLRDSHIFQLFWREAAEPLSEPKEDQEAAELLSEPEEESERHILELEEVYDYLYQPSYRKFIKLHQDLKSGEVTLA
EIDVIFKDFVNKYTDLDSELKIMCTVDHQDQRDWIKDRVEQIKEYHHLHQAVHAAKVILQVKESLGLNGDFSVLNTLLNFTDNFDDFRRE
TLDQINQELIQAKKLLQDISEARCKGLQALSLRKEFICWVREALGGINELKVFVDLASISAGENDIDVDRVACFHDAVQGYASLLFKLDP
SVDFSAFMKHLKKLWKALDKDQYLPRKLCDSARNLEWLKTVNESHGSVERSSLTLATAINQRGIYVIQAPKGGQKISPDTVLHLILPESP
GSHEESREYSLEEVKELLNKLMLMSGKKDRNNTEVERFSEVFCSVQRLSQAFIDLHSAGNMLFRTWIAMAYCSPKQGVSLQMDFGLDLVT
ELKEGGDVTELLAALCRQMEHFLDSWKRFVTQKRMEHFYLNFYTAEQLVYLSTELRKQPPSDAALTMLSFIKSNCTLRDVLRASVGCGSE
AARYRMRRVMEELPLMLLSEFSLVDKLRIIMEQSMRCLPAFLPDCLDLETLGHCLAHLAGMGGSPVERCLPRGLQVGQPNLVVCGHSEVL
PAALAVYMQTPSQPLPTYDEVLLCTPATTFEEVALLLRRCLTLGSLGHKVYSLLFADQLSYEVARQAEELFHNLCTQQHREDYQLVMVCD
GDWEHCYLPSAFSQHKVFVTPQAPLEAIQAYLAGHYRVPKQTLSAAAVFNDRLCVGIVASERAGVGKSLYVKRLHDKMKMQLNVKNVPLK
TIRLIDPQVDESRVLGALLPFLDAQYQKVPVLFHLDVTSSVQTGIWVFLFKLLILQYLMDINGKMWLRNPCHLYIVEILERRTSVPSRSS
SALRTRVPQFSFLDIFPKVTCRPPKEVIDMELSALRSDTEPGMDLWEFCSETFQRPYQYLRRFNQNQDLDTFQYQEGSVEGTPEECLQHF
LFHCGVINPSWSELRNFARFLNYQLRDCEASLFCNPSFIGDTLRGFKKFVVTFMIFMARDFATPSLHTSDQSPGKHMVTMDGVREEDLAP
FSLRKRWESEPHPYVFFNDDHTTMTFIGFHLQPNINGSVDAISHLTGKVIKRDVMTRDLYQGLLLQRVPFNVDFDKLPRHKKLERLCLTL
GIPQATDPDKTYELTTDNMLKILAIEMRFRCGIPVIIMGETGCGKTRLIKFLSDLRRGGTNADTIKLVKVHGGTTADMIYSRVREAENVA
FANKDQHQLDTILFFDEANTTEAISCIKEVLCDHMVDGQPLAEDSGLHIIAACNPYRKHSEEMICRLESAGLGYRVSMEETADRLGSIPL
RQLVYRVHALPPSLIPLVWDFGQLSDVAEKLYIQQIVQRLVESISLDENGTRVITEVLCASQGFMRKTEDECSFVSLRDVERCVKVFRWF
HEHSAMLLAQLNAFLSKSSVSKNHTERDPVLWSLMLAIGVCYHASLEKKDSYRKAIARFFPKPYDDSRLLLDEITRAQDLFLDGVPLRKT
IAKNLALKENVFMMVVCIELKIPLFLVGKPGSSKSLAKTIVADAMQGPAAYSDLFRSLKQVHLVSFQCSPHSTPQGIISTFRQCARFQQG
KDLQQYVSVVVLDEVGLAEDSPKMPLKTLHPLLEDGCIEDDPAPHKKVGFVGISNWALDPAKMNRGIFVSRGSPNETELIESAKGICSSD
ILVQDRVQGYFASFAKAYETVCKRQDKEFFGLRDYYSLIKMVFAAAKASNRKPSPQDIAQAVLRNFSGKDDIQALDIFLANLPEAKCSEE
VSPMQLIKQNIFGPSQKVPGGEQEDAESRYLLVLTKNYVALQILQQTFFEGDQQPEIIFGSGFPKDQEYTQLCRNINRVKICMETGKMVL
LLNLQNLYESLYDALNQYYVHLGGQKYVDLGLGTHRVKCRVHPNFRLIVIEEKDVVYKHFPIPLINRLEKHYLDINTVLEKWQKSIVEEL
CAWVEKFINVKAHHFQKRHKYSPSDVFIGYHSDACASVVLQVIERQGPRALTEELHQKVSEEAKSILLNCATPDAVVRLSAYSLGGFAAE
WLSQEYFHRQRHNSFADFLQAHLHTADLERHAIFTEITTFSRLLTSHDCEILESEVTGRAPKPTLLWLQQFDTEYSFLKEVRNCLTNTAK
CKILIFQTDFEDGIRSAQLIASAKYSVINEINKIRENEDRIFVYFITKLSRVGRGTAYVGFHGGLWQSVHIDDLRRSTLMVSDVTRLQHV
TISQLFAPGDLPELGLEHRAEDGHEEAMETEASTSGEVAEVAEEAMETESSEKVGKETSELGGSDVSILDTTRLLRSCVQSAVGMLRDQN
ESCTRNMRRVVLLLGLLNEDDACHASFLRVSKMRLSVFLKKQEESQFHPLEWLAREACNQDALQEAGTFRHTLWKRVQGAVTPLLASMIS
FIDRDGNLELLTRPDTPPWARDLWMFIFSDTMLLNIPLVMNNERHKGEMAYIVVQNHMNLSENASNNVPFSWKIKDYLEELWVQAQYITD
AEGLPKKFVDIFQQTPLGRFLAQLHGEPQQELLQCYLKDFILLTMRVSTEEELKFLQMALWSCTRKLKAASEAPEEEVSLPWVHLAYQRF
RSRLQNFSRILTIYPQVLHSLMEARWNHELAGCEMTLDAFAAMACTEMLTRNTLKPSPQAWLQLVKNLSMPLELICSDEHMQGSGSLAQA
VIREVRAQWSRIFSTALFVEHVLLGTESRVPELQGLVTEHVFLLDKCLRENSDVKTHGPFEAVMRTLCECKETASKTLSRFGIQPCSICL
GDAKDPVCLPCDHVHCLRCLRAWFASEQMICPYCLTALPDEFSPAVSQAHREAIEKHARFRQMCNSFFVDLVSTICFKDNAPPEKEVIES
LLSLLFVQKGRLRDAAQRHCEHTKSLSPFNDVVDKTPVIRSVILKLLLKYSFHDVKDYIQEYLTLLKKKAFITEDKTELYMLFINCLEDS
ILEKTSAYSRNDELNHLEEEGRFLKAYSPASRGREPANEASVEYLQEVARIRLCLDRAADFLSEPEGGPEMAKEKQCYLQQVKQFCIRVE
NDWHRVYLVRKLSSQRGMEFVQGLSKPGRPHQWVFPKDVVKQQGLRQDHPGQMDRYLVYGDEYKALRDAVAKAVLECKPLGIKTALKACK
TPQSQQSAYFLLTLFREVAILYRSHNASLHPTPEQCEAVSKFIGECKILSPPDISRFATSLVDNSVPLLRAGPSDSNLDGTVTEMAIHAA
AVLLCGQNELLEPLKNLAFSPATMAHAFLPTMPEDLLAQARRWKGLERVHWYTCPNGHPCSVGECGRPMEQSICIDCHAPIGGIDHKPRD
GFHLVKDKADRTQTGHVLGNPQRRDVVTCDRGLPPVVFLLIRLLTHLALLLGASQSSQISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNL
VYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMS
TPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGASRAADDAERERRDREERLRHSRNPATR

--------------------------------------------------------------
>74967_74967_6_RNF213-CSNK1D_RNF213_chr17_78354787_ENST00000508628_CSNK1D_chr17_80211120_ENST00000398519_length(transcript)=15286nt_BP=14089nt
GACAGCGCGCGGCAGGCGGCGAGCTCGGGGGCCGCAGAAAATGAAACTGAAGCCGTGGTCACGTGACAGGACATGTAGTATATAGCAGGC
TGCCAGCGACTCCTGCTCTTGCTTCTGGATCTGCAGGGCAGTCCCAGCAGGACCCATGGAGTGTCCTTCGTGCCAGCATGTCTCCAAGGA
GGAAACCCCCAAGTTCTGCAGCCAGTGCGGAGAGAGGCTGCCTCCTGCAGCCCCCATAGCAGATTCTGAGAACAATAACTCCACAATGGC
GTCGGCCTCGGAGGGTGAAATGGAGTGTGGGCAGGAGCTGAAGGAGGAAGGGGGCCCGTGCTTGTTCCCGGGCTCAGACAGTTGGCAAGA
AAACCCCGAGGAGCCCTGTTCCAAAGCCTCCTGGACCGTCCAAGAAGGAGCTACATCAGAGGTTTTGGTAGATGCTGCTGTAGACCTCAT
ATCCGATGAATGGGAAGCTGCTAATGCCATACCCAGCAAGAGAAGGAAGCAGGATGCAGCCCCGCTTGAGGCCGCCAGCGTGCCTTCTGC
AGACTGTGAGCAGAGCAAAAAGAAGAAAAGGAAGAAGAAAAAGAAGGGGAACAAGTCCGCTTCCTCAGAGCTGGCTTCCTTGCCCCTTTC
TCCTGCCAGCCCCTGTCACCTGACTTTGCTTTCAAACCCGTGGCCTCAGGACACAGCCCTGCCCCACAGCCAAGCCCAGCAGAGTGGCCC
CACTGGCCAGCCGAGCCAGCCCCCAGGCACAGCCACCACGCCACTGGAGGGTGACGGCCTCTCCGCGCCCACCGAGGTTGGCGACAGCCC
CCTGCAGGCCCAGGCTTTGGGAGAGGCAGGAGTGGCCACAGGAAGTGAGGCTCAGAGCAGCCCGCAATTCCAGGACCACACGGAAGGGGA
GGACCAGGACGCTTCCATCCCCTCTGGGGGCAGAGGCCTGTCCCAGGAGGGGACCGGTCCCCCCACCTCTGCTGGTGAAGGCCATTCTAG
GACTGAAGATGCTGCCCAGGAGCTCCTGTTGCCTGAGTCAAAAGGAGGCAGCTCTGAGCCCGGGACAGAACTGCAGACCACCGAGCAACA
GGCAGGGGCCTCAGCCTCTATGGCAGTTGATGCTGTAGCTGAGCCAGCCAATGCAGTTAAAGGGGCCGGGAAGGAAATGAAAGAGAAGAC
CCAGAGAATGAAACAGCCACCAGCAACCACTCCTCCTTTCAAAACACACTGCCAGGAAGCTGAGACCAAGACCAAGGACGAGATGGCTGC
TGCTGAAGAAAAAGTCGGTAAGAATGAACAAGGGGAGCCTGAAGACCTCAAGAAGCCAGAGGGGAAGAACAGAAGTGCAGCTGCTGTGAA
AAACGAGAAGGAGCAAAAAAACCAGGAAGCAGATGTCCAGGAAGTGAAGGCAAGCACGCTGAGCCCGGGTGGAGGAGTCACCGTGTTCTT
CCACGCCATCATCTCTCTTCATTTCCCATTCAATCCTGACCTCCATAAAGTCTTCATCAGAGGAGGAGAAGAATTTGGGGAGTCAAAATG
GGACAGCAATATCTGTGAGCTGCACTACACCAGAGACTTGGGTCATGACCGCGTTCTTGTTGAAGGCATTGTCTGCATTTCCAAGAAGCA
CCTAGATAAATACATTCCTTACAAGTACGTCATTTATAATGGGGAATCTTTTGAGTATGAGTTCATTTACAAGCACCAGCAGAAGAAGGG
CGAGTACGTCAACCGCTGTCTGTTCATAAAATCTTCACTTCTGGGCTCAGGAGACTGGCATCAGTACTATGACATAGTTTATATGAAGCC
TCATGGGAGACTCCAGAAAGTCATGAACCACATCACAGACGGGCCGAGGAAGGACCTGGTGAAGGGGAAGCAGATTGCCGCTGCGCTCAT
GCTGGACAGCACCTTCAGCATCCTGCAGACCTGGGACACCATCAACCTGAACAGCTTCTTCACCCAGTTCGAGCAGTTTTGCTTTGTCCT
GCAACAGCCTATGATTTATGAAGGACAGGCACAGCTGTGGACCGATTTGCAGTACAGGGAGAAAGAGGTGAAGAGATACCTGTGGCAACA
TCTGAAAAAACACGTGGTACCATTGCCGGACGGAAAAAGCACGGACTTTTTGCCTGTGGACTGCCCAGTGAGGAGTAAACTGAAAACAGG
CCTGATTGTCCTTTTTGTAGTGGAAAAAATTGAGCTTTTATTAGAAGGCAGCCTGGACTGGTTGTGTCACCTCCTAACCTCAGATGCCAG
CTCACCAGATGAGTTTCACCGTGACCTAAGCCACATCCTTGGGATACCTCAGAGCTGGCGGCTGTACCTGGTGAACCTGTGCCAAAGATG
CATGGACACAAGGACGTACACCTGGCTGGGCGCCCTGCCTGTCCTGCACTGCTGTATGGAGCTGGCCCCGCGGCACAAGGATGCCTGGAG
ACAGCCTGAGGACACCTGGGCCGCTCTGGAGGGACTCTCCTTCTCACCGTTCCGGGAACAAATGCTAGATACGAGTTCCCTACTTCAGTT
TATGAGAGAGAAGCAGCATTTGCTGAGCATAGACGAGCCTCTCTTCCGGTCCTGGTTTAGTCTGCTACCTCTGAGTCACCTGGTTATGTA
TATGGAAAACTTCATTGAGCACCTGGGTCGTTTTCCTGCTCATATCCTGGACTGTCTTTCAGGGATTTACTACCGGCTTCCGGGACTTGA
GCAAGTCTTGAATACGCAGGATGTTCAGGATGTTCAGAACGTTCAGAACATTTTAGAAATGCTGTTGCGACTCCTGGACACTTACCGGGA
CAAGATTCCCGAGGAGGCCTTGTCACCATCCTACCTGACTGTGTGTCTGAAACTGCATGAAGCCATCTGCAGCAGCACAAAGCTACTTAA
GTTTTACGAGCTGCCAGCCTTATCTGCCGAGATTGTCTGCAGAATGATTAGACTTCTATCTCTGGTGGATTCTGCAGGACAGAGAGATGA
AACTGGAAATAATTCAGTCCAAACAGTCTTCCAAGGGACCCTTGCTGCTACGAAAAGGTGGCTCCGAGAAGTTTTTACAAAGAACATGCT
CACATCTTCAGGTGCCTCATTCACATACGTCAAGGAAATTGAGGTCTGGAGGCGGCTGGTGGAAATCCAATTCCCCGCGGAGCATGGCTG
GAAGGAGTCGTTGCTGGGAGACATGGAATGGAGGCTCACAAAGGAGGAACCCCTCTCCCAGATCACTGCCTACTGCAATAGTTGCTGGGA
CACCAAAGGCTTAGAGGACAGTGTGGCCAAGACCTTCGAGAAATGCATCATTGAAGCCGTGAGCTCAGCCTGCCAGTCTCAGACCAGTAT
CCTTCAGGGGTTCTCTTACTCTGATTTGCGGAAATTTGGCATCGTCTTGTCTGCTGTGATCACTAAGTCCTGGCCTAGGACCGCGGACAA
CTTCAATGACATTTTAAAGCATCTGCTCACGTTGGCAGATGTCAAGCACGTCTTCAGATTGTGTGGAACCGACGAGAAAATACTAGCAAA
TGTCACAGAGGATGCCAAGAGGCTGATAGCTGTTGCCGACTCTGTGTTGACGAAAGTTGTTGGTGACCTCCTAAGTGGCACGATTTTAGT
TGGACAACTGGAGCTGATTATAAAGCACAAGAATCAGTTTCTTGACATCTGGCAACTGAGGGAAAAAAGTCTTTCACCCCAGGATGAACA
ATGTGCTGTGGAGGAAGCACTGGATTGGAGAAGGGAGGAACTGTTACTTCTAAAGAAAGAGAAAAGATGTGTTGATAGTCTCCTGAAGAT
GTGTGGGAACGTGAAACATCTGATACAAGTGGACTTTGGAGTGCTTGCAGTAAGACACTCACAAGACCTCAGCAGTAAAAGATTAAATGA
CACCGTGACAGTGAGACTGTCCACCTCCTCGAACTCGCAGAGGGCAACGCATTACCACCTGAGCTCCCAGGTCCAAGAAATGGCTGGGAA
GATAGACTTGCTCAGAGACAGCCACATCTTCCAGCTCTTCTGGCGGGAAGCCGCAGAGCCGCTGAGTGAGCCTAAGGAGGACCAGGAAGC
CGCAGAGTTGCTGAGTGAGCCCGAAGAAGAATCAGAAAGGCACATCCTTGAGCTTGAAGAGGTGTATGACTATTTGTATCAGCCTTCTTA
CAGAAAGTTCATTAAGTTGCACCAGGATCTAAAGTCAGGAGAGGTCACCCTTGCAGAGATTGATGTCATCTTCAAGGACTTTGTGAATAA
ATACACGGACCTGGATTCAGAACTTAAGATCATGTGCACCGTGGACCACCAGGACCAAAGAGATTGGATCAAGGACCGAGTCGAACAGAT
CAAGGAATACCATCACCTGCACCAGGCTGTCCACGCAGCCAAGGTCATCTTGCAGGTCAAAGAGAGCCTGGGACTGAACGGTGACTTCAG
TGTTCTCAACACTTTACTAAATTTTACTGATAACTTCGACGACTTTCGCCGTGAAACACTGGACCAGATCAACCAGGAGCTCATCCAGGC
CAAAAAGCTGCTCCAGGACATCAGCGAGGCCCGGTGCAAGGGGCTGCAGGCTCTGTCCCTGAGAAAGGAGTTCATCTGCTGGGTCCGGGA
GGCTCTTGGAGGCATCAATGAGCTGAAGGTGTTTGTGGACCTGGCCTCCATCTCAGCGGGGGAGAATGACATTGATGTGGACCGGGTGGC
CTGCTTCCATGACGCTGTGCAGGGCTACGCATCCCTGCTATTTAAGCTGGACCCCAGCGTGGACTTCAGTGCATTCATGAAGCATCTGAA
AAAGCTGTGGAAGGCTCTGGATAAGGACCAGTACCTGCCCAGGAAACTGTGTGACTCCGCCAGGAACTTGGAATGGCTGAAGACTGTGAA
TGAGAGTCATGGGTCTGTGGAACGCTCATCCCTGACCCTGGCCACGGCCATCAACCAAAGAGGCATCTATGTGATCCAGGCGCCCAAAGG
TGGCCAAAAGATTTCCCCAGACACGGTTCTGCACTTGATCCTTCCTGAGAGCCCTGGCAGCCACGAGGAGTCACGAGAGTACTCTTTAGA
GGAGGTGAAGGAGCTTTTGAACAAGTTGATGCTGATGTCTGGCAAGAAGGATCGTAACAACACGGAAGTGGAGAGGTTTTCAGAGGTCTT
CTGCAGTGTGCAGAGGCTCAGCCAGGCCTTCATCGACCTGCACTCTGCTGGGAATATGCTGTTCAGGACGTGGATCGCCATGGCCTACTG
CTCCCCCAAGCAGGGTGTGTCCCTCCAAATGGACTTTGGCTTGGACCTGGTGACGGAGCTTAAAGAAGGTGGAGATGTCACTGAGCTGCT
GGCAGCCCTCTGCAGGCAGATGGAGCACTTCCTTGACAGCTGGAAGAGATTTGTGACCCAGAAGCGAATGGAGCACTTTTACCTGAACTT
CTACACGGCAGAGCAGCTGGTTTACCTGAGCACTGAGCTCAGGAAGCAGCCCCCGAGTGATGCCGCCCTAACGATGCTATCCTTCATCAA
AAGCAACTGCACCCTGAGGGATGTCTTAAGGGCCTCTGTGGGGTGTGGGAGTGAGGCCGCCAGGTACCGCATGAGGAGAGTCATGGAAGA
GCTCCCGCTGATGCTCTTATCAGAGTTCAGCCTGGTGGACAAGCTGAGGATCATCATGGAGCAGTCCATGAGGTGCCTTCCTGCCTTCCT
GCCCGACTGCCTCGACCTAGAGACCCTTGGCCACTGTCTGGCTCACCTGGCAGGGATGGGTGGGTCTCCCGTGGAGCGTTGTCTCCCGAG
AGGTCTGCAGGTCGGCCAGCCCAACCTCGTCGTCTGTGGCCACTCCGAGGTGTTGCCAGCCGCCCTGGCTGTCTACATGCAAACCCCAAG
CCAGCCCCTGCCCACTTACGATGAGGTGCTGCTCTGCACCCCGGCAACCACCTTTGAGGAGGTGGCACTGTTGCTGCGCCGCTGCCTGAC
CCTGGGCTCCCTGGGGCACAAGGTCTACAGCCTGCTGTTCGCAGATCAGCTGAGCTACGAGGTGGCACGCCAAGCGGAGGAGCTTTTCCA
CAATCTGTGCACGCAGCAGCACCGAGAAGACTACCAGCTCGTCATGGTCTGTGATGGGGACTGGGAGCACTGCTACCTCCCCTCTGCCTT
CAGCCAGCACAAGGTCTTCGTCACCCCCCAGGCACCCCTCGAGGCCATCCAAGCCTACCTGGCAGGTCACTACCGGGTCCCGAAGCAGAC
CCTGTCGGCGGCAGCCGTGTTCAATGACCGGCTGTGTGTTGGGATCGTGGCCTCGGAGCGAGCAGGTGTTGGAAAGTCTCTGTACGTGAA
GAGGTTGCACGACAAAATGAAGATGCAGTTAAACGTGAAAAATGTGCCTCTGAAAACAATTCGACTGATCGACCCTCAGGTGGATGAGAG
CCGAGTCCTGGGCGCCCTGCTGCCCTTCCTGGATGCGCAGTATCAGAAGGTCCCCGTGCTCTTTCACCTGGACGTGACCTCCTCAGTGCA
GACTGGAATTTGGGTGTTTCTTTTCAAGCTCCTCATTTTACAATACTTAATGGATATAAATGGGAAAATGTGGCTTCGGAACCCCTGCCA
TTTGTATATCGTTGAAATCCTGGAAAGGAGGACGTCAGTGCCGTCGAGGAGCTCTTCAGCGCTGCGTACACGTGTACCCCAGTTCAGTTT
TCTTGACATCTTCCCAAAAGTCACCTGCAGGCCTCCCAAAGAGGTGATAGACATGGAGCTGAGTGCCCTGAGGAGTGACACAGAGCCTGG
GATGGATCTGTGGGAGTTCTGCAGCGAAACTTTCCAAAGACCTTACCAGTATTTAAGACGATTCAATCAAAACCAAGACCTAGACACGTT
TCAGTATCAAGAAGGCTCTGTCGAAGGCACCCCGGAGGAATGCCTCCAGCATTTCCTGTTTCACTGCGGGGTAATAAACCCATCCTGGTC
AGAGCTTCGGAACTTTGCTCGGTTCCTGAATTATCAGCTCAGAGATTGTGAGGCCTCTCTCTTCTGCAATCCGAGTTTTATTGGCGACAC
ACTGAGGGGCTTCAAGAAGTTCGTGGTGACCTTCATGATCTTTATGGCAAGAGATTTTGCCACACCATCACTCCACACCTCTGACCAAAG
CCCGGGGAAGCACATGGTCACCATGGATGGGGTTAGGGAAGAAGATCTAGCGCCCTTCTCCCTCCGGAAGAGGTGGGAGTCGGAGCCTCA
CCCATACGTTTTCTTCAATGACGACCACACAACCATGACATTCATCGGCTTCCATCTGCAGCCCAACATCAACGGCAGTGTCGATGCCAT
CAGTCACTTGACTGGGAAGGTCATCAAGAGAGACGTCATGACCAGGGACCTGTACCAGGGCCTGCTGCTCCAGAGGGTGCCCTTCAATGT
CGACTTTGATAAACTGCCCAGACACAAGAAACTTGAGAGGCTCTGCCTGACCTTAGGGATCCCCCAGGCCACCGACCCCGACAAAACGTA
TGAGCTCACAACCGACAATATGCTTAAAATCCTTGCCATCGAGATGCGGTTCCGGTGTGGGATCCCGGTTATCATCATGGGAGAAACTGG
CTGTGGGAAAACCAGGCTTATTAAATTCCTTAGCGACCTGCGGCGTGGTGGTACCAATGCTGACACCATAAAGCTGGTCAAGGTGCACGG
AGGAACAACTGCAGACATGATCTACTCCAGAGTCAGGGAGGCTGAAAATGTGGCCTTCGCCAATAAGGACCAACATCAGTTGGACACCAT
CTTGTTTTTTGATGAAGCCAACACAACGGAAGCTATAAGCTGTATCAAAGAAGTCCTGTGTGATCATATGGTGGATGGCCAGCCTCTGGC
TGAGGACTCTGGCCTGCATATTATAGCTGCCTGCAATCCATACCGGAAGCACTCTGAGGAGATGATCTGCCGTTTGGAGTCAGCTGGTTT
GGGCTACAGGGTTAGTATGGAGGAGACGGCCGACAGGCTGGGCTCCATTCCTCTGAGGCAGCTGGTATACCGGGTCCATGCTCTGCCCCC
GAGCCTGATTCCTCTGGTGTGGGACTTTGGACAACTGAGTGACGTTGCTGAAAAGCTCTACATCCAGCAGATTGTCCAGAGACTGGTTGA
GTCCATCAGCCTAGATGAAAACGGGACTCGCGTGATCACAGAAGTCCTCTGCGCCTCTCAGGGTTTCATGAGGAAAACAGAAGATGAGTG
CAGCTTTGTCAGCCTCAGGGACGTGGAGCGCTGTGTGAAAGTTTTCAGGTGGTTCCACGAGCACAGCGCGATGCTCTTAGCGCAGCTGAA
TGCCTTTCTCTCCAAGTCCAGCGTCAGCAAAAATCACACCGAGAGAGATCCCGTCCTCTGGTCGTTGATGCTGGCCATCGGGGTGTGTTA
CCATGCCTCTTTAGAAAAGAAAGACTCATATCGGAAAGCCATCGCCAGGTTCTTTCCGAAACCGTATGACGACAGCAGGCTGCTTCTGGA
TGAAATAACACGGGCACAGGATCTTTTTCTGGACGGCGTACCTCTGAGGAAAACCATCGCCAAGAACTTGGCCTTGAAGGAGAACGTCTT
CATGATGGTCGTCTGCATCGAGCTGAAGATTCCCCTCTTCCTGGTGGGGAAGCCCGGCAGCTCCAAGTCTCTCGCCAAGACCATCGTGGC
AGACGCCATGCAGGGCCCGGCTGCCTACTCAGATCTCTTCCGCAGCCTGAAGCAGGTCCACCTGGTGTCCTTCCAGTGCAGCCCGCACTC
CACCCCACAGGGCATCATCAGCACCTTCCGGCAGTGCGCCCGCTTTCAGCAGGGGAAGGACCTGCAGCAGTACGTCTCTGTGGTGGTGTT
AGATGAGGTGGGGCTGGCGGAAGACTCACCCAAAATGCCCCTGAAGACTCTGCACCCGCTGCTGGAAGACGGATGCATTGAAGACGATCC
CGCCCCCCACAAAAAGGTCGGCTTCGTGGGCATCTCCAACTGGGCCCTTGACCCTGCCAAGATGAACCGGGGCATTTTTGTGTCACGTGG
CAGCCCCAACGAGACAGAGCTCATAGAGAGCGCCAAGGGCATCTGCTCCTCAGACATCCTCGTCCAGGACCGAGTCCAAGGGTACTTTGC
GTCCTTTGCCAAAGCCTACGAAACGGTGTGTAAGCGCCAGGACAAGGAATTCTTCGGGCTTCGTGACTACTACAGCCTCATCAAAATGGT
CTTTGCTGCAGCAAAGGCTTCAAATAGAAAGCCTTCCCCGCAAGACATTGCACAGGCTGTCCTTAGGAACTTCAGTGGCAAGGATGACAT
CCAAGCTTTGGACATCTTTCTGGCCAATTTGCCCGAGGCCAAGTGCTCAGAGGAAGTCAGCCCCATGCAGCTGATCAAACAGAACATCTT
TGGGCCTTCTCAGAAGGTGCCGGGTGGAGAGCAGGAAGATGCTGAGTCCCGCTACTTACTCGTGCTGACCAAAAACTACGTGGCACTGCA
GATCCTGCAGCAGACATTCTTCGAGGGGGACCAGCAGCCGGAGATTATTTTTGGTTCTGGTTTCCCCAAGGACCAAGAGTACACCCAGCT
CTGCAGAAACATCAATCGTGTGAAGATCTGCATGGAAACAGGCAAGATGGTGTTGCTTCTCAACCTGCAGAACCTCTACGAGAGCCTCTA
CGACGCACTCAACCAGTACTACGTCCACCTCGGCGGCCAGAAGTACGTGGACCTCGGTCTGGGGACCCACCGCGTCAAATGTCGGGTTCA
CCCCAACTTCCGCCTGATTGTCATTGAAGAGAAAGACGTCGTGTACAAACACTTTCCCATCCCCCTCATTAACCGGCTGGAGAAGCACTA
TCTGGATATCAACACGGTGCTGGAGAAATGGCAGAAGAGCATCGTGGAGGAGCTCTGTGCGTGGGTGGAGAAGTTCATCAATGTCAAAGC
ACATCATTTCCAGAAGAGGCACAAATACAGCCCCTCTGACGTCTTCATCGGCTACCACTCGGACGCCTGCGCGTCTGTGGTGCTGCAGGT
CATAGAGAGGCAGGGTCCCCGGGCCTTGACGGAGGAACTTCACCAGAAGGTGTCTGAGGAGGCCAAATCGATCCTGCTGAACTGCGCTAC
GCCCGATGCCGTGGTCCGGCTGAGCGCCTACTCGCTGGGCGGGTTCGCAGCGGAGTGGCTGTCGCAGGAGTACTTTCACAGACAGAGGCA
CAACTCCTTTGCAGATTTCCTTCAGGCACACCTGCACACGGCAGACCTGGAGCGCCACGCCATCTTCACAGAGATCACCACTTTCTCCAG
GCTGCTAACAAGTCACGACTGTGAAATTTTAGAATCAGAGGTCACAGGCAGGGCTCCGAAACCCACACTCCTGTGGCTGCAGCAGTTTGA
CACCGAGTACTCATTCCTCAAAGAAGTCCGAAACTGTTTAACGAATACAGCCAAATGTAAAATCCTCATTTTTCAGACAGATTTTGAAGA
TGGAATCCGTAGCGCCCAGCTCATTGCCTCAGCTAAGTATTCTGTTATAAATGAAATCAACAAAATACGAGAAAATGAGGACCGTATCTT
CGTCTATTTCATCACAAAACTGTCCCGGGTGGGAAGAGGAACAGCCTATGTGGGCTTCCACGGAGGGCTGTGGCAGTCTGTCCACATCGA
TGACCTCCGGAGATCCACCCTCATGGTTTCTGATGTGACCAGGCTGCAGCATGTCACCATCAGCCAGCTGTTCGCGCCCGGAGACTTGCC
TGAGCTGGGCTTGGAACACCGGGCGGAAGACGGCCATGAGGAGGCGATGGAGACGGAGGCCAGCACATCAGGGGAGGTGGCAGAGGTGGC
AGAGGAGGCCATGGAAACAGAAAGTTCTGAGAAGGTGGGAAAGGAAACCTCTGAACTCGGAGGCAGTGATGTGTCGATCCTGGACACCAC
CAGGCTGCTGAGAAGCTGTGTGCAGAGCGCCGTGGGCATGCTCAGAGACCAGAACGAGAGCTGCACGCGCAATATGCGGAGGGTGGTGCT
CCTCCTGGGCCTCTTGAATGAGGATGACGCGTGCCACGCCTCTTTCTTGCGGGTATCCAAGATGCGCCTCAGTGTCTTTTTAAAGAAGCA
AGAAGAGAGCCAGTTTCACCCTCTGGAGTGGTTGGCAAGGGAAGCCTGCAACCAGGACGCTCTCCAGGAGGCGGGCACATTCAGGCACAC
CCTCTGGAAGCGGGTCCAAGGTGCTGTCACCCCTCTGCTGGCGAGCATGATATCATTCATCGACAGAGACGGCAACCTAGAGTTACTGAC
CAGGCCAGATACTCCGCCCTGGGCAAGAGATCTTTGGATGTTTATTTTCAGTGACACGATGCTTCTGAACATTCCTCTTGTGATGAATAA
TGAAAGACATAAAGGTGAGATGGCCTACATCGTGGTGCAGAACCACATGAACCTTTCCGAGAACGCTTCCAACAACGTCCCTTTCAGCTG
GAAAATCAAGGACTATCTGGAGGAGCTGTGGGTCCAGGCTCAGTACATCACAGACGCAGAAGGACTGCCCAAGAAGTTCGTGGACATCTT
TCAGCAGACTCCTCTGGGCAGGTTTCTTGCCCAGCTCCATGGAGAGCCGCAGCAGGAACTTCTTCAGTGTTACTTGAAGGATTTCATTCT
CTTGACCATGCGTGTGTCAACGGAGGAGGAATTAAAGTTTCTGCAGATGGCTCTGTGGTCCTGCACTAGGAAACTGAAAGCGGCGTCAGA
AGCGCCCGAGGAAGAGGTTTCCTTACCGTGGGTGCACCTTGCCTACCAGCGTTTCAGAAGCCGTCTGCAGAACTTTTCCAGAATCCTGAC
CATCTACCCTCAGGTTCTCCACAGCCTGATGGAAGCCCGTTGGAACCATGAGCTGGCTGGATGTGAGATGACCCTGGACGCATTTGCCGC
AATGGCCTGCACGGAGATGCTGACAAGAAACACCCTGAAGCCCAGTCCCCAGGCGTGGCTACAGTTGGTGAAGAATCTTTCCATGCCGCT
GGAGCTCATCTGCTCCGATGAGCACATGCAAGGCAGCGGGAGCCTGGCCCAGGCTGTCATCAGGGAAGTCAGAGCCCAGTGGAGTCGGAT
TTTCTCCACCGCACTCTTCGTGGAGCACGTGCTCCTAGGAACCGAGAGCCGCGTCCCCGAGTTACAGGGGCTGGTGACCGAGCACGTCTT
CTTACTAGACAAGTGTCTTCGAGAGAACTCTGACGTGAAGACGCACGGGCCTTTTGAGGCCGTGATGCGCACTCTCTGTGAATGCAAGGA
GACAGCCAGCAAGACCCTCAGCAGGTTTGGGATTCAGCCGTGCTCCATCTGCCTGGGAGATGCAAAGGACCCCGTCTGTCTGCCCTGCGA
CCACGTGCACTGCCTGCGCTGCCTCAGGGCCTGGTTTGCCTCAGAGCAGATGATATGCCCCTACTGTTTAACTGCCTTGCCAGACGAATT
CTCTCCAGCTGTTTCCCAAGCGCACAGGGAAGCCATTGAAAAGCATGCCCGCTTCCGGCAGATGTGCAACAGTTTCTTCGTAGACCTGGT
GTCCACCATTTGCTTCAAGGACAACGCTCCGCCTGAGAAGGAAGTGATTGAGAGCCTGCTCTCTCTCCTCTTCGTCCAAAAGGGGCGCTT
AAGAGATGCTGCCCAGAGACACTGTGAACACACAAAATCTCTCTCTCCATTCAATGATGTTGTGGATAAGACTCCTGTCATCCGCTCAGT
GATACTGAAACTGCTTTTGAAGTACAGCTTTCATGATGTAAAAGATTATATTCAGGAATATTTGACCCTGTTAAAAAAGAAAGCATTCAT
AACTGAAGATAAAACTGAACTGTACATGCTCTTCATCAACTGCCTGGAGGATTCAATACTTGAGAAGACCAGTGCTTACTCCAGAAATGA
TGAACTGAACCACCTAGAAGAGGAAGGTCGTTTCCTTAAGGCATATTCTCCAGCAAGCCGGGGCCGAGAGCCTGCCAACGAGGCCTCGGT
TGAATACCTGCAAGAGGTGGCCCGGATCCGCCTCTGCCTCGACAGAGCTGCAGATTTCCTCTCGGAGCCTGAGGGAGGCCCAGAGATGGC
CAAGGAGAAGCAGTGCTACCTGCAGCAAGTCAAGCAGTTCTGTATCCGGGTGGAGAACGACTGGCACCGGGTGTACCTGGTGCGGAAGCT
CAGCAGCCAGCGGGGGATGGAGTTCGTGCAGGGCCTCTCCAAGCCCGGCCGCCCGCACCAGTGGGTGTTTCCCAAGGACGTTGTCAAGCA
GCAGGGGCTGCGGCAGGACCACCCAGGCCAGATGGATAGGTACCTGGTGTACGGCGATGAATACAAGGCTCTCCGTGATGCTGTGGCCAA
AGCTGTCCTCGAGTGCAAGCCACTGGGCATTAAGACTGCTCTGAAGGCCTGCAAGACCCCCCAAAGCCAGCAGTCAGCCTACTTCCTGTT
AACACTGTTTAGAGAGGTGGCTATTTTGTACAGATCCCACAATGCAAGCCTCCACCCCACGCCAGAGCAATGTGAAGCTGTGAGCAAATT
CATTGGCGAATGCAAGATCCTTTCACCTCCTGATATCAGCCGTTTTGCAACATCGCTCGTGGACAATTCTGTGCCATTGTTGAGGGCGGG
GCCTAGTGACAGCAACCTTGATGGAACGGTGACAGAAATGGCCATTCATGCTGCAGCCGTCCTTCTGTGTGGACAGAATGAACTCTTGGA
GCCCCTAAAGAATCTGGCCTTCTCCCCAGCCACCATGGCGCATGCTTTTCTTCCAACCATGCCTGAAGACTTGCTGGCTCAAGCTCGGAG
GTGGAAGGGTCTGGAGCGAGTCCACTGGTACACTTGTCCCAACGGCCATCCTTGCTCCGTGGGAGAGTGTGGCAGGCCGATGGAACAGAG
CATCTGCATTGACTGCCATGCGCCGATTGGAGGCATTGACCACAAACCTCGGGACGGCTTTCATCTGGTCAAAGACAAGGCAGACAGAAC
GCAGACCGGCCACGTGCTGGGCAACCCGCAGCGGAGAGACGTGGTGACATGTGACCGAGGGCTGCCCCCAGTGGTCTTCCTCCTTATCCG
GCTACTCACTCACTTGGCTCTGCTTCTGGGAGCGTCCCAGAGTTCCCAGATCAGTCGCATCGAATACATTCATTCAAAGAACTTCATCCA
CCGGGATGTGAAGCCAGACAACTTCCTCATGGGCCTGGGGAAGAAGGGCAACCTGGTGTACATCATCGACTTCGGGCTGGCCAAGAAGTA
CCGGGATGCACGCACCCACCAGCACATCCCCTATCGTGAGAACAAGAACCTCACGGGGACGGCGCGGTACGCCTCCATCAACACGCACCT
TGGAATTGAACAATCCCGAAGAGATGACTTGGAGTCTCTGGGCTACGTGCTAATGTACTTCAACCTGGGCTCTCTCCCCTGGCAGGGGCT
GAAGGCTGCCACCAAGAGACAGAAATACGAAAGGATTAGCGAGAAGAAAATGTCCACCCCCATCGAAGTGTTGTGTAAAGGCTACCCTTC
CGAATTTGCCACATACCTGAATTTCTGCCGTTCCTTGCGTTTTGACGACAAGCCTGACTACTCGTACCTGCGGCAGCTTTTCCGGAATCT
GTTCCATCGCCAGGGCTTCTCCTATGACTACGTGTTCGACTGGAACATGCTCAAATTTGGTGCCAGCCGGGCCGCCGATGACGCCGAGCG
GGAGCGCAGGGACCGAGAGGAGCGGCTGAGACACTCGCGGAACCCGGCTACCCGCGGCCTCCCTTCCACAGCCTCCGGCCGCCTGCGGGG
GACGCAGGAAGTGGCTCCCCCCACACCCCTCACCCCTACCTCACACACGGCTAACACCTCCCCCCGGCCCGTCTCCGGCATGGAGAGAGA
GCGGAAAGTGAGTATGCGGCTGCACCGCGGGGCCCCCGTCAACATCTCCTCGTCCGACCTCACAGGCCGACAAGATACCTCTCGCATGTC
CACCTCACAGAGGAGCAGGGACATGGCATCTCTCCGGCTGCACGCGGCCCGCCAGGGCACCCGCTGCCGTCCCCAGCGCCCACGACGCAC
CTACTGAGGGCCCCGGCGGCCTCTGACCGGGCTCCCAGCCACGCAGGCCACTGCTGGCCACGAGGGCAGGTGGGTGTTAGGTGTCCAGGA
CAAGCCCAAGCGCTGGGCCGGGCTGGATGGAGGACAGGGTGCAAAGACCAGCCCTGGGCACTGACCACACCACGCACACTGCCAGCCAGG

>74967_74967_6_RNF213-CSNK1D_RNF213_chr17_78354787_ENST00000508628_CSNK1D_chr17_80211120_ENST00000398519_length(amino acids)=4963AA_BP=4646
MECPSCQHVSKEETPKFCSQCGERLPPAAPIADSENNNSTMASASEGEMECGQELKEEGGPCLFPGSDSWQENPEEPCSKASWTVQEGAT
SEVLVDAAVDLISDEWEAANAIPSKRRKQDAAPLEAASVPSADCEQSKKKKRKKKKKGNKSASSELASLPLSPASPCHLTLLSNPWPQDT
ALPHSQAQQSGPTGQPSQPPGTATTPLEGDGLSAPTEVGDSPLQAQALGEAGVATGSEAQSSPQFQDHTEGEDQDASIPSGGRGLSQEGT
GPPTSAGEGHSRTEDAAQELLLPESKGGSSEPGTELQTTEQQAGASASMAVDAVAEPANAVKGAGKEMKEKTQRMKQPPATTPPFKTHCQ
EAETKTKDEMAAAEEKVGKNEQGEPEDLKKPEGKNRSAAAVKNEKEQKNQEADVQEVKASTLSPGGGVTVFFHAIISLHFPFNPDLHKVF
IRGGEEFGESKWDSNICELHYTRDLGHDRVLVEGIVCISKKHLDKYIPYKYVIYNGESFEYEFIYKHQQKKGEYVNRCLFIKSSLLGSGD
WHQYYDIVYMKPHGRLQKVMNHITDGPRKDLVKGKQIAAALMLDSTFSILQTWDTINLNSFFTQFEQFCFVLQQPMIYEGQAQLWTDLQY
REKEVKRYLWQHLKKHVVPLPDGKSTDFLPVDCPVRSKLKTGLIVLFVVEKIELLLEGSLDWLCHLLTSDASSPDEFHRDLSHILGIPQS
WRLYLVNLCQRCMDTRTYTWLGALPVLHCCMELAPRHKDAWRQPEDTWAALEGLSFSPFREQMLDTSSLLQFMREKQHLLSIDEPLFRSW
FSLLPLSHLVMYMENFIEHLGRFPAHILDCLSGIYYRLPGLEQVLNTQDVQDVQNVQNILEMLLRLLDTYRDKIPEEALSPSYLTVCLKL
HEAICSSTKLLKFYELPALSAEIVCRMIRLLSLVDSAGQRDETGNNSVQTVFQGTLAATKRWLREVFTKNMLTSSGASFTYVKEIEVWRR
LVEIQFPAEHGWKESLLGDMEWRLTKEEPLSQITAYCNSCWDTKGLEDSVAKTFEKCIIEAVSSACQSQTSILQGFSYSDLRKFGIVLSA
VITKSWPRTADNFNDILKHLLTLADVKHVFRLCGTDEKILANVTEDAKRLIAVADSVLTKVVGDLLSGTILVGQLELIIKHKNQFLDIWQ
LREKSLSPQDEQCAVEEALDWRREELLLLKKEKRCVDSLLKMCGNVKHLIQVDFGVLAVRHSQDLSSKRLNDTVTVRLSTSSNSQRATHY
HLSSQVQEMAGKIDLLRDSHIFQLFWREAAEPLSEPKEDQEAAELLSEPEEESERHILELEEVYDYLYQPSYRKFIKLHQDLKSGEVTLA
EIDVIFKDFVNKYTDLDSELKIMCTVDHQDQRDWIKDRVEQIKEYHHLHQAVHAAKVILQVKESLGLNGDFSVLNTLLNFTDNFDDFRRE
TLDQINQELIQAKKLLQDISEARCKGLQALSLRKEFICWVREALGGINELKVFVDLASISAGENDIDVDRVACFHDAVQGYASLLFKLDP
SVDFSAFMKHLKKLWKALDKDQYLPRKLCDSARNLEWLKTVNESHGSVERSSLTLATAINQRGIYVIQAPKGGQKISPDTVLHLILPESP
GSHEESREYSLEEVKELLNKLMLMSGKKDRNNTEVERFSEVFCSVQRLSQAFIDLHSAGNMLFRTWIAMAYCSPKQGVSLQMDFGLDLVT
ELKEGGDVTELLAALCRQMEHFLDSWKRFVTQKRMEHFYLNFYTAEQLVYLSTELRKQPPSDAALTMLSFIKSNCTLRDVLRASVGCGSE
AARYRMRRVMEELPLMLLSEFSLVDKLRIIMEQSMRCLPAFLPDCLDLETLGHCLAHLAGMGGSPVERCLPRGLQVGQPNLVVCGHSEVL
PAALAVYMQTPSQPLPTYDEVLLCTPATTFEEVALLLRRCLTLGSLGHKVYSLLFADQLSYEVARQAEELFHNLCTQQHREDYQLVMVCD
GDWEHCYLPSAFSQHKVFVTPQAPLEAIQAYLAGHYRVPKQTLSAAAVFNDRLCVGIVASERAGVGKSLYVKRLHDKMKMQLNVKNVPLK
TIRLIDPQVDESRVLGALLPFLDAQYQKVPVLFHLDVTSSVQTGIWVFLFKLLILQYLMDINGKMWLRNPCHLYIVEILERRTSVPSRSS
SALRTRVPQFSFLDIFPKVTCRPPKEVIDMELSALRSDTEPGMDLWEFCSETFQRPYQYLRRFNQNQDLDTFQYQEGSVEGTPEECLQHF
LFHCGVINPSWSELRNFARFLNYQLRDCEASLFCNPSFIGDTLRGFKKFVVTFMIFMARDFATPSLHTSDQSPGKHMVTMDGVREEDLAP
FSLRKRWESEPHPYVFFNDDHTTMTFIGFHLQPNINGSVDAISHLTGKVIKRDVMTRDLYQGLLLQRVPFNVDFDKLPRHKKLERLCLTL
GIPQATDPDKTYELTTDNMLKILAIEMRFRCGIPVIIMGETGCGKTRLIKFLSDLRRGGTNADTIKLVKVHGGTTADMIYSRVREAENVA
FANKDQHQLDTILFFDEANTTEAISCIKEVLCDHMVDGQPLAEDSGLHIIAACNPYRKHSEEMICRLESAGLGYRVSMEETADRLGSIPL
RQLVYRVHALPPSLIPLVWDFGQLSDVAEKLYIQQIVQRLVESISLDENGTRVITEVLCASQGFMRKTEDECSFVSLRDVERCVKVFRWF
HEHSAMLLAQLNAFLSKSSVSKNHTERDPVLWSLMLAIGVCYHASLEKKDSYRKAIARFFPKPYDDSRLLLDEITRAQDLFLDGVPLRKT
IAKNLALKENVFMMVVCIELKIPLFLVGKPGSSKSLAKTIVADAMQGPAAYSDLFRSLKQVHLVSFQCSPHSTPQGIISTFRQCARFQQG
KDLQQYVSVVVLDEVGLAEDSPKMPLKTLHPLLEDGCIEDDPAPHKKVGFVGISNWALDPAKMNRGIFVSRGSPNETELIESAKGICSSD
ILVQDRVQGYFASFAKAYETVCKRQDKEFFGLRDYYSLIKMVFAAAKASNRKPSPQDIAQAVLRNFSGKDDIQALDIFLANLPEAKCSEE
VSPMQLIKQNIFGPSQKVPGGEQEDAESRYLLVLTKNYVALQILQQTFFEGDQQPEIIFGSGFPKDQEYTQLCRNINRVKICMETGKMVL
LLNLQNLYESLYDALNQYYVHLGGQKYVDLGLGTHRVKCRVHPNFRLIVIEEKDVVYKHFPIPLINRLEKHYLDINTVLEKWQKSIVEEL
CAWVEKFINVKAHHFQKRHKYSPSDVFIGYHSDACASVVLQVIERQGPRALTEELHQKVSEEAKSILLNCATPDAVVRLSAYSLGGFAAE
WLSQEYFHRQRHNSFADFLQAHLHTADLERHAIFTEITTFSRLLTSHDCEILESEVTGRAPKPTLLWLQQFDTEYSFLKEVRNCLTNTAK
CKILIFQTDFEDGIRSAQLIASAKYSVINEINKIRENEDRIFVYFITKLSRVGRGTAYVGFHGGLWQSVHIDDLRRSTLMVSDVTRLQHV
TISQLFAPGDLPELGLEHRAEDGHEEAMETEASTSGEVAEVAEEAMETESSEKVGKETSELGGSDVSILDTTRLLRSCVQSAVGMLRDQN
ESCTRNMRRVVLLLGLLNEDDACHASFLRVSKMRLSVFLKKQEESQFHPLEWLAREACNQDALQEAGTFRHTLWKRVQGAVTPLLASMIS
FIDRDGNLELLTRPDTPPWARDLWMFIFSDTMLLNIPLVMNNERHKGEMAYIVVQNHMNLSENASNNVPFSWKIKDYLEELWVQAQYITD
AEGLPKKFVDIFQQTPLGRFLAQLHGEPQQELLQCYLKDFILLTMRVSTEEELKFLQMALWSCTRKLKAASEAPEEEVSLPWVHLAYQRF
RSRLQNFSRILTIYPQVLHSLMEARWNHELAGCEMTLDAFAAMACTEMLTRNTLKPSPQAWLQLVKNLSMPLELICSDEHMQGSGSLAQA
VIREVRAQWSRIFSTALFVEHVLLGTESRVPELQGLVTEHVFLLDKCLRENSDVKTHGPFEAVMRTLCECKETASKTLSRFGIQPCSICL
GDAKDPVCLPCDHVHCLRCLRAWFASEQMICPYCLTALPDEFSPAVSQAHREAIEKHARFRQMCNSFFVDLVSTICFKDNAPPEKEVIES
LLSLLFVQKGRLRDAAQRHCEHTKSLSPFNDVVDKTPVIRSVILKLLLKYSFHDVKDYIQEYLTLLKKKAFITEDKTELYMLFINCLEDS
ILEKTSAYSRNDELNHLEEEGRFLKAYSPASRGREPANEASVEYLQEVARIRLCLDRAADFLSEPEGGPEMAKEKQCYLQQVKQFCIRVE
NDWHRVYLVRKLSSQRGMEFVQGLSKPGRPHQWVFPKDVVKQQGLRQDHPGQMDRYLVYGDEYKALRDAVAKAVLECKPLGIKTALKACK
TPQSQQSAYFLLTLFREVAILYRSHNASLHPTPEQCEAVSKFIGECKILSPPDISRFATSLVDNSVPLLRAGPSDSNLDGTVTEMAIHAA
AVLLCGQNELLEPLKNLAFSPATMAHAFLPTMPEDLLAQARRWKGLERVHWYTCPNGHPCSVGECGRPMEQSICIDCHAPIGGIDHKPRD
GFHLVKDKADRTQTGHVLGNPQRRDVVTCDRGLPPVVFLLIRLLTHLALLLGASQSSQISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNL
VYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMS
TPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGASRAADDAERERRDREERLRHSRNPATR
GLPSTASGRLRGTQEVAPPTPLTPTSHTANTSPRPVSGMERERKVSMRLHRGAPVNISSSDLTGRQDTSRMSTSQRSRDMASLRLHAARQ

--------------------------------------------------------------
>74967_74967_7_RNF213-CSNK1D_RNF213_chr17_78354787_ENST00000582970_CSNK1D_chr17_80211120_ENST00000314028_length(transcript)=16966nt_BP=13940nt
CAGCGCGCGGCAGGCGGCGAGCTCGGGGGCCGCAGAAAATGAAACTGAAGCCGTGGTCACGTGACAGGACATGTAGTATATAGCAGGCTG
CCAGCGACTCCTGCTCTTGCTTCTGGATCTGCAGGGCAGTCCCAGCAGGACCCATGGAGTGTCCTTCGTGCCAGCATGTCTCCAAGGAGG
AAACCCCCAAGTTCTGCAGCCAGTGCGGAGAGAGGCTGCCTCCTGCAGCCCCCATAGCAGATTCTGAGAACAATAACTCCACAATGGCGT
CGGCCTCGGAGGGTGAAATGGAGTGTGGGCAGGAGCTGAAGGAGGAAGGGGGCCCGTGCTTGTTCCCGGGCTCAGACAGTTGGCAAGAAA
ACCCCGAGGAGCCCTGTTCCAAAGCCTCCTGGACCGTCCAAGAAAGCAAAAAGAAGAAAAGGAAGAAGAAAAAGAAGGGGAACAAGTCCG
CTTCCTCAGAGCTGGCTTCCTTGCCCCTTTCTCCTGCCAGCCCCTGTCACCTGACTTTGCTTTCAAACCCGTGGCCTCAGGACACAGCCC
TGCCCCACAGCCAAGCCCAGCAGAGTGGCCCCACTGGCCAGCCGAGCCAGCCCCCAGGCACAGCCACCACGCCACTGGAGGGTGACGGCC
TCTCCGCGCCCACCGAGGTTGGCGACAGCCCCCTGCAGGCCCAGGCTTTGGGAGAGGCAGGAGTGGCCACAGGAAGTGAGGCTCAGAGCA
GCCCGCAATTCCAGGACCACACGGAAGGGGAGGACCAGGACGCTTCCATCCCCTCTGGGGGCAGAGGCCTGTCCCAGGAGGGGACCGGTC
CCCCCACCTCTGCTGGTGAAGGCCATTCTAGGACTGAAGATGCTGCCCAGGAGCTCCTGTTGCCTGAGTCAAAAGGAGGCAGCTCTGAGC
CCGGGACAGAACTGCAGACCACCGAGCAACAGGCAGGGGCCTCAGCCTCTATGGCAGTTGATGCTGTAGCTGAGCCAGCCAATGCAGTTA
AAGGGGCCGGGAAGGAAATGAAAGAGAAGACCCAGAGAATGAAACAGCCACCAGCAACCACTCCTCCTTTCAAAACACACTGCCAGGAAG
CTGAGACCAAGACCAAGGACGAGATGGCTGCTGCTGAAGAAAAAGTCGGTAAGAATGAACAAGGGGAGCCTGAAGACCTCAAGAAGCCAG
AGGGGAAGAACAGAAGTGCAGCTGCTGTGAAAAACGAGAAGGAGCAAAAAAACCAGGAAGCAGATGTCCAGGAAGTGAAGGCAAGCACGC
TGAGCCCGGGTGGAGGAGTCACCGTGTTCTTCCACGCCATCATCTCTCTTCATTTCCCATTCAATCCTGACCTCCATAAAGTCTTCATCA
GAGGAGGAGAAGAATTTGGGGAGTCAAAATGGGACAGCAATATCTGTGAGCTGCACTACACCAGAGACTTGGGTCATGACCGCGTTCTTG
TTGAAGGCATTGTCTGCATTTCCAAGAAGCACCTAGATAAATACATTCCTTACAAGTACGTCATTTATAATGGGGAATCTTTTGAGTATG
AGTTCATTTACAAGCACCAGCAGAAGAAGGGCGAGTACGTCAACCGCTGTCTGTTCATAAAATCTTCACTTCTGGGCTCAGGAGACTGGC
ATCAGTACTATGACATAGTTTATATGAAGCCTCATGGGAGACTCCAGAAAGTCATGAACCACATCACAGACGGGCCGAGGAAGGACCTGG
TGAAGGGGAAGCAGATTGCCGCTGCGCTCATGCTGGACAGCACCTTCAGCATCCTGCAGACCTGGGACACCATCAACCTGAACAGCTTCT
TCACCCAGTTCGAGCAGTTTTGCTTTGTCCTGCAACAGCCTATGATTTATGAAGGACAGGCACAGCTGTGGACCGATTTGCAGTACAGGG
AGAAAGAGGTGAAGAGATACCTGTGGCAACATCTGAAAAAACACGTGGTACCATTGCCGGACGGAAAAAGCACGGACTTTTTGCCTGTGG
ACTGCCCAGTGAGGAGTAAACTGAAAACAGGCCTGATTGTCCTTTTTGTAGTGGAAAAAATTGAGCTTTTATTAGAAGGCAGCCTGGACT
GGTTGTGTCACCTCCTAACCTCAGATGCCAGCTCACCAGATGAGTTTCACCGTGACCTAAGCCACATCCTTGGGATACCTCAGAGCTGGC
GGCTGTACCTGGTGAACCTGTGCCAAAGATGCATGGACACAAGGACGTACACCTGGCTGGGCGCCCTGCCTGTCCTGCACTGCTGTATGG
AGCTGGCCCCGCGGCACAAGGATGCCTGGAGACAGCCTGAGGACACCTGGGCCGCTCTGGAGGGACTCTCCTTCTCACCGTTCCGGGAAC
AAATGCTAGATACGAGTTCCCTACTTCAGTTTATGAGAGAGAAGCAGCATTTGCTGAGCATAGACGAGCCTCTCTTCCGGTCCTGGTTTA
GTCTGCTACCTCTGAGTCACCTGGTTATGTATATGGAAAACTTCATTGAGCACCTGGGTCGTTTTCCTGCTCATATCCTGGACTGTCTTT
CAGGGATTTACTACCGGCTTCCGGGACTTGAGCAAGTCTTGAATACGCAGGATGTTCAGGATGTTCAGAACGTTCAGAACATTTTAGAAA
TGCTGTTGCGACTCCTGGACACTTACCGGGACAAGATTCCCGAGGAGGCCTTGTCACCATCCTACCTGACTGTGTGTCTGAAACTGCATG
AAGCCATCTGCAGCAGCACAAAGCTACTTAAGTTTTACGAGCTGCCAGCCTTATCTGCCGAGATTGTCTGCAGAATGATTAGACTTCTAT
CTCTGGTGGATTCTGCAGGACAGAGAGATGAAACTGGAAATAATTCAGTCCAAACAGTCTTCCAAGGGACCCTTGCTGCTACGAAAAGGT
GGCTCCGAGAAGTTTTTACAAAGAACATGCTCACATCTTCAGGTGCCTCATTCACATACGTCAAGGAAATTGAGGTCTGGAGGCGGCTGG
TGGAAATCCAATTCCCCGCGGAGCATGGCTGGAAGGAGTCGTTGCTGGGAGACATGGAATGGAGGCTCACAAAGGAGGAACCCCTCTCCC
AGATCACTGCCTACTGCAATAGTTGCTGGGACACCAAAGGCTTAGAGGACAGTGTGGCCAAGACCTTCGAGAAATGCATCATTGAAGCCG
TGAGCTCAGCCTGCCAGTCTCAGACCAGTATCCTTCAGGGGTTCTCTTACTCTGATTTGCGGAAATTTGGCATCGTCTTGTCTGCTGTGA
TCACTAAGTCCTGGCCTAGGACCGCGGACAACTTCAATGACATTTTAAAGCATCTGCTCACGTTGGCAGATGTCAAGCACGTCTTCAGAT
TGTGTGGAACCGACGAGAAAATACTAGCAAATGTCACAGAGGATGCCAAGAGGCTGATAGCTGTTGCCGACTCTGTGTTGACGAAAGTTG
TTGGTGACCTCCTAAGTGGCACGATTTTAGTTGGACAACTGGAGCTGATTATAAAGCACAAGAATCAGTTTCTTGACATCTGGCAACTGA
GGGAAAAAAGTCTTTCACCCCAGGATGAACAATGTGCTGTGGAGGAAGCACTGGATTGGAGAAGGGAGGAACTGTTACTTCTAAAGAAAG
AGAAAAGATGTGTTGATAGTCTCCTGAAGATGTGTGGGAACGTGAAACATCTGATACAAGTGGACTTTGGAGTGCTTGCAGTAAGACACT
CACAAGACCTCAGCAGTAAAAGATTAAATGACACCGTGACAGTGAGACTGTCCACCTCCTCGAACTCGCAGAGGGCAACGCATTACCACC
TGAGCTCCCAGGTCCAAGAAATGGCTGGGAAGATAGACTTGCTCAGAGACAGCCACATCTTCCAGCTCTTCTGGCGGGAAGCCGCAGAGC
CGCTGAGTGAGCCTAAGGAGGACCAGGAAGCCGCAGAGTTGCTGAGTGAGCCCGAAGAAGAATCAGAAAGGCACATCCTTGAGCTTGAAG
AGGTGTATGACTATTTGTATCAGCCTTCTTACAGAAAGTTCATTAAGTTGCACCAGGATCTAAAGTCAGGAGAGGTCACCCTTGCAGAGA
TTGATGTCATCTTCAAGGACTTTGTGAATAAATACACGGACCTGGATTCAGAACTTAAGATCATGTGCACCGTGGACCACCAGGACCAAA
GAGATTGGATCAAGGACCGAGTCGAACAGATCAAGGAATACCATCACCTGCACCAGGCTGTCCACGCAGCCAAGGTCATCTTGCAGGTCA
AAGAGAGCCTGGGACTGAACGGTGACTTCAGTGTTCTCAACACTTTACTAAATTTTACTGATAACTTCGACGACTTTCGCCGTGAAACAC
TGGACCAGATCAACCAGGAGCTCATCCAGGCCAAAAAGCTGCTCCAGGACATCAGCGAGGCCCGGTGCAAGGGGCTGCAGGCTCTGTCCC
TGAGAAAGGAGTTCATCTGCTGGGTCCGGGAGGCTCTTGGAGGCATCAATGAGCTGAAGGTGTTTGTGGACCTGGCCTCCATCTCAGCGG
GGGAGAATGACATTGATGTGGACCGGGTGGCCTGCTTCCATGACGCTGTGCAGGGCTACGCATCCCTGCTATTTAAGCTGGACCCCAGCG
TGGACTTCAGTGCATTCATGAAGCATCTGAAAAAGCTGTGGAAGGCTCTGGATAAGGACCAGTACCTGCCCAGGAAACTGTGTGACTCCG
CCAGGAACTTGGAATGGCTGAAGACTGTGAATGAGAGTCATGGGTCTGTGGAACGCTCATCCCTGACCCTGGCCACGGCCATCAACCAAA
GAGGCATCTATGTGATCCAGGCGCCCAAAGGTGGCCAAAAGATTTCCCCAGACACGGTTCTGCACTTGATCCTTCCTGAGAGCCCTGGCA
GCCACGAGGAGTCACGAGAGTACTCTTTAGAGGAGGTGAAGGAGCTTTTGAACAAGTTGATGCTGATGTCTGGCAAGAAGGATCGTAACA
ACACGGAAGTGGAGAGGTTTTCAGAGGTCTTCTGCAGTGTGCAGAGGCTCAGCCAGGCCTTCATCGACCTGCACTCTGCTGGGAATATGC
TGTTCAGGACGTGGATCGCCATGGCCTACTGCTCCCCCAAGCAGGGTGTGTCCCTCCAAATGGACTTTGGCTTGGACCTGGTGACGGAGC
TTAAAGAAGGTGGAGATGTCACTGAGCTGCTGGCAGCCCTCTGCAGGCAGATGGAGCACTTCCTTGACAGCTGGAAGAGATTTGTGACCC
AGAAGCGAATGGAGCACTTTTACCTGAACTTCTACACGGCAGAGCAGCTGGTTTACCTGAGCACTGAGCTCAGGAAGCAGCCCCCGAGTG
ATGCCGCCCTAACGATGCTATCCTTCATCAAAAGCAACTGCACCCTGAGGGATGTCTTAAGGGCCTCTGTGGGGTGTGGGAGTGAGGCCG
CCAGGTACCGCATGAGGAGAGTCATGGAAGAGCTCCCGCTGATGCTCTTATCAGAGTTCAGCCTGGTGGACAAGCTGAGGATCATCATGG
AGCAGTCCATGAGGTGCCTTCCTGCCTTCCTGCCCGACTGCCTCGACCTAGAGACCCTTGGCCACTGTCTGGCTCACCTGGCAGGGATGG
GTGGGTCTCCCGTGGAGCGTTGTCTCCCGAGAGGTCTGCAGGTCGGCCAGCCCAACCTCGTCGTCTGTGGCCACTCCGAGGTGTTGCCAG
CCGCCCTGGCTGTCTACATGCAAACCCCAAGCCAGCCCCTGCCCACTTACGATGAGGTGCTGCTCTGCACCCCGGCAACCACCTTTGAGG
AGGTGGCACTGTTGCTGCGCCGCTGCCTGACCCTGGGCTCCCTGGGGCACAAGGTCTACAGCCTGCTGTTCGCAGATCAGCTGAGCTACG
AGGTGGCACGCCAAGCGGAGGAGCTTTTCCACAATCTGTGCACGCAGCAGCACCGAGAAGACTACCAGCTCGTCATGGTCTGTGATGGGG
ACTGGGAGCACTGCTACCTCCCCTCTGCCTTCAGCCAGCACAAGGTCTTCGTCACCCCCCAGGCACCCCTCGAGGCCATCCAAGCCTACC
TGGCAGGTCACTACCGGGTCCCGAAGCAGACCCTGTCGGCGGCAGCCGTGTTCAATGACCGGCTGTGTGTTGGGATCGTGGCCTCGGAGC
GAGCAGGTGTTGGAAAGTCTCTGTACGTGAAGAGGTTGCACGACAAAATGAAGATGCAGTTAAACGTGAAAAATGTGCCTCTGAAAACAA
TTCGACTGATCGACCCTCAGGTGGATGAGAGCCGAGTCCTGGGCGCCCTGCTGCCCTTCCTGGATGCGCAGTATCAGAAGGTCCCCGTGC
TCTTTCACCTGGACGTGACCTCCTCAGTGCAGACTGGAATTTGGGTGTTTCTTTTCAAGCTCCTCATTTTACAATACTTAATGGATATAA
ATGGGAAAATGTGGCTTCGGAACCCCTGCCATTTGTATATCGTTGAAATCCTGGAAAGGAGGACGTCAGTGCCGTCGAGGAGCTCTTCAG
CGCTGCGTACACGTGTACCCCAGTTCAGTTTTCTTGACATCTTCCCAAAAGTCACCTGCAGGCCTCCCAAAGAGGTGATAGACATGGAGC
TGAGTGCCCTGAGGAGTGACACAGAGCCTGGGATGGATCTGTGGGAGTTCTGCAGCGAAACTTTCCAAAGACCTTACCAGTATTTAAGAC
GATTCAATCAAAACCAAGACCTAGACACGTTTCAGTATCAAGAAGGCTCTGTCGAAGGCACCCCGGAGGAATGCCTCCAGCATTTCCTGT
TTCACTGCGGGGTAATAAACCCATCCTGGTCAGAGCTTCGGAACTTTGCTCGGTTCCTGAATTATCAGCTCAGAGATTGTGAGGCCTCTC
TCTTCTGCAATCCGAGTTTTATTGGCGACACACTGAGGGGCTTCAAGAAGTTCGTGGTGACCTTCATGATCTTTATGGCAAGAGATTTTG
CCACACCATCACTCCACACCTCTGACCAAAGCCCGGGGAAGCACATGGTCACCATGGATGGGGTTAGGGAAGAAGATCTAGCGCCCTTCT
CCCTCCGGAAGAGGTGGGAGTCGGAGCCTCACCCATACGTTTTCTTCAATGACGACCACACAACCATGACATTCATCGGCTTCCATCTGC
AGCCCAACATCAACGGCAGTGTCGATGCCATCAGTCACTTGACTGGGAAGGTCATCAAGAGAGACGTCATGACCAGGGACCTGTACCAGG
GCCTGCTGCTCCAGAGGGTGCCCTTCAATGTCGACTTTGATAAACTGCCCAGACACAAGAAACTTGAGAGGCTCTGCCTGACCTTAGGGA
TCCCCCAGGCCACCGACCCCGACAAAACGTATGAGCTCACAACCGACAATATGCTTAAAATCCTTGCCATCGAGATGCGGTTCCGGTGTG
GGATCCCGGTTATCATCATGGGAGAAACTGGCTGTGGGAAAACCAGGCTTATTAAATTCCTTAGCGACCTGCGGCGTGGTGGTACCAATG
CTGACACCATAAAGCTGGTCAAGGTGCACGGAGGAACAACTGCAGACATGATCTACTCCAGAGTCAGGGAGGCTGAAAATGTGGCCTTCG
CCAATAAGGACCAACATCAGTTGGACACCATCTTGTTTTTTGATGAAGCCAACACAACGGAAGCTATAAGCTGTATCAAAGAAGTCCTGT
GTGATCATATGGTGGATGGCCAGCCTCTGGCTGAGGACTCTGGCCTGCATATTATAGCTGCCTGCAATCCATACCGGAAGCACTCTGAGG
AGATGATCTGCCGTTTGGAGTCAGCTGGTTTGGGCTACAGGGTTAGTATGGAGGAGACGGCCGACAGGCTGGGCTCCATTCCTCTGAGGC
AGCTGGTATACCGGGTCCATGCTCTGCCCCCGAGCCTGATTCCTCTGGTGTGGGACTTTGGACAACTGAGTGACGTTGCTGAAAAGCTCT
ACATCCAGCAGATTGTCCAGAGACTGGTTGAGTCCATCAGCCTAGATGAAAACGGGACTCGCGTGATCACAGAAGTCCTCTGCGCCTCTC
AGGGTTTCATGAGGAAAACAGAAGATGAGTGCAGCTTTGTCAGCCTCAGGGACGTGGAGCGCTGTGTGAAAGTTTTCAGGTGGTTCCACG
AGCACAGCGCGATGCTCTTAGCGCAGCTGAATGCCTTTCTCTCCAAGTCCAGCGTCAGCAAAAATCACACCGAGAGAGATCCCGTCCTCT
GGTCGTTGATGCTGGCCATCGGGGTGTGTTACCATGCCTCTTTAGAAAAGAAAGACTCATATCGGAAAGCCATCGCCAGGTTCTTTCCGA
AACCGTATGACGACAGCAGGCTGCTTCTGGATGAAATAACACGGGCACAGGATCTTTTTCTGGACGGCGTACCTCTGAGGAAAACCATCG
CCAAGAACTTGGCCTTGAAGGAGAACGTCTTCATGATGGTCGTCTGCATCGAGCTGAAGATTCCCCTCTTCCTGGTGGGGAAGCCCGGCA
GCTCCAAGTCTCTCGCCAAGACCATCGTGGCAGACGCCATGCAGGGCCCGGCTGCCTACTCAGATCTCTTCCGCAGCCTGAAGCAGGTCC
ACCTGGTGTCCTTCCAGTGCAGCCCGCACTCCACCCCACAGGGCATCATCAGCACCTTCCGGCAGTGCGCCCGCTTTCAGCAGGGGAAGG
ACCTGCAGCAGTACGTCTCTGTGGTGGTGTTAGATGAGGTGGGGCTGGCGGAAGACTCACCCAAAATGCCCCTGAAGACTCTGCACCCGC
TGCTGGAAGACGGATGCATTGAAGACGATCCCGCCCCCCACAAAAAGGTCGGCTTCGTGGGCATCTCCAACTGGGCCCTTGACCCTGCCA
AGATGAACCGGGGCATTTTTGTGTCACGTGGCAGCCCCAACGAGACAGAGCTCATAGAGAGCGCCAAGGGCATCTGCTCCTCAGACATCC
TCGTCCAGGACCGAGTCCAAGGGTACTTTGCGTCCTTTGCCAAAGCCTACGAAACGGTGTGTAAGCGCCAGGACAAGGAATTCTTCGGGC
TTCGTGACTACTACAGCCTCATCAAAATGGTCTTTGCTGCAGCAAAGGCTTCAAATAGAAAGCCTTCCCCGCAAGACATTGCACAGGCTG
TCCTTAGGAACTTCAGTGGCAAGGATGACATCCAAGCTTTGGACATCTTTCTGGCCAATTTGCCCGAGGCCAAGTGCTCAGAGGAAGTCA
GCCCCATGCAGCTGATCAAACAGAACATCTTTGGGCCTTCTCAGAAGGTGCCGGGTGGAGAGCAGGAAGATGCTGAGTCCCGCTACTTAC
TCGTGCTGACCAAAAACTACGTGGCACTGCAGATCCTGCAGCAGACATTCTTCGAGGGGGACCAGCAGCCGGAGATTATTTTTGGTTCTG
GTTTCCCCAAGGACCAAGAGTACACCCAGCTCTGCAGAAACATCAATCGTGTGAAGATCTGCATGGAAACAGGCAAGATGGTGTTGCTTC
TCAACCTGCAGAACCTCTACGAGAGCCTCTACGACGCACTCAACCAGTACTACGTCCACCTCGGCGGCCAGAAGTACGTGGACCTCGGTC
TGGGGACCCACCGCGTCAAATGTCGGGTTCACCCCAACTTCCGCCTGATTGTCATTGAAGAGAAAGACGTCGTGTACAAACACTTTCCCA
TCCCCCTCATTAACCGGCTGGAGAAGCACTATCTGGATATCAACACGGTGCTGGAGAAATGGCAGAAGAGCATCGTGGAGGAGCTCTGTG
CGTGGGTGGAGAAGTTCATCAATGTCAAAGCACATCATTTCCAGAAGAGGCACAAATACAGCCCCTCTGACGTCTTCATCGGCTACCACT
CGGACGCCTGCGCGTCTGTGGTGCTGCAGGTCATAGAGAGGCAGGGTCCCCGGGCCTTGACGGAGGAACTTCACCAGAAGGTGTCTGAGG
AGGCCAAATCGATCCTGCTGAACTGCGCTACGCCCGATGCCGTGGTCCGGCTGAGCGCCTACTCGCTGGGCGGGTTCGCAGCGGAGTGGC
TGTCGCAGGAGTACTTTCACAGACAGAGGCACAACTCCTTTGCAGATTTCCTTCAGGCACACCTGCACACGGCAGACCTGGAGCGCCACG
CCATCTTCACAGAGATCACCACTTTCTCCAGGCTGCTAACAAGTCACGACTGTGAAATTTTAGAATCAGAGGTCACAGGCAGGGCTCCGA
AACCCACACTCCTGTGGCTGCAGCAGTTTGACACCGAGTACTCATTCCTCAAAGAAGTCCGAAACTGTTTAACGAATACAGCCAAATGTA
AAATCCTCATTTTTCAGACAGATTTTGAAGATGGAATCCGTAGCGCCCAGCTCATTGCCTCAGCTAAGTATTCTGTTATAAATGAAATCA
ACAAAATACGAGAAAATGAGGACCGTATCTTCGTCTATTTCATCACAAAACTGTCCCGGGTGGGAAGAGGAACAGCCTATGTGGGCTTCC
ACGGAGGGCTGTGGCAGTCTGTCCACATCGATGACCTCCGGAGATCCACCCTCATGGTTTCTGATGTGACCAGGCTGCAGCATGTCACCA
TCAGCCAGCTGTTCGCGCCCGGAGACTTGCCTGAGCTGGGCTTGGAACACCGGGCGGAAGACGGCCATGAGGAGGCGATGGAGACGGAGG
CCAGCACATCAGGGGAGGTGGCAGAGGTGGCAGAGGAGGCCATGGAAACAGAAAGTTCTGAGAAGGTGGGAAAGGAAACCTCTGAACTCG
GAGGCAGTGATGTGTCGATCCTGGACACCACCAGGCTGCTGAGAAGCTGTGTGCAGAGCGCCGTGGGCATGCTCAGAGACCAGAACGAGA
GCTGCACGCGCAATATGCGGAGGGTGGTGCTCCTCCTGGGCCTCTTGAATGAGGATGACGCGTGCCACGCCTCTTTCTTGCGGGTATCCA
AGATGCGCCTCAGTGTCTTTTTAAAGAAGCAAGAAGAGAGCCAGTTTCACCCTCTGGAGTGGTTGGCAAGGGAAGCCTGCAACCAGGACG
CTCTCCAGGAGGCGGGCACATTCAGGCACACCCTCTGGAAGCGGGTCCAAGGTGCTGTCACCCCTCTGCTGGCGAGCATGATATCATTCA
TCGACAGAGACGGCAACCTAGAGTTACTGACCAGGCCAGATACTCCGCCCTGGGCAAGAGATCTTTGGATGTTTATTTTCAGTGACACGA
TGCTTCTGAACATTCCTCTTGTGATGAATAATGAAAGACATAAAGGTGAGATGGCCTACATCGTGGTGCAGAACCACATGAACCTTTCCG
AGAACGCTTCCAACAACGTCCCTTTCAGCTGGAAAATCAAGGACTATCTGGAGGAGCTGTGGGTCCAGGCTCAGTACATCACAGACGCAG
AAGGACTGCCCAAGAAGTTCGTGGACATCTTTCAGCAGACTCCTCTGGGCAGGTTTCTTGCCCAGCTCCATGGAGAGCCGCAGCAGGAAC
TTCTTCAGTGTTACTTGAAGGATTTCATTCTCTTGACCATGCGTGTGTCAACGGAGGAGGAATTAAAGTTTCTGCAGATGGCTCTGTGGT
CCTGCACTAGGAAACTGAAAGCGGCGTCAGAAGCGCCCGAGGAAGAGGTTTCCTTACCGTGGGTGCACCTTGCCTACCAGCGTTTCAGAA
GCCGTCTGCAGAACTTTTCCAGAATCCTGACCATCTACCCTCAGGTTCTCCACAGCCTGATGGAAGCCCGTTGGAACCATGAGCTGGCTG
GATGTGAGATGACCCTGGACGCATTTGCCGCAATGGCCTGCACGGAGATGCTGACAAGAAACACCCTGAAGCCCAGTCCCCAGGCGTGGC
TACAGTTGGTGAAGAATCTTTCCATGCCGCTGGAGCTCATCTGCTCCGATGAGCACATGCAAGGCAGCGGGAGCCTGGCCCAGGCTGTCA
TCAGGGAAGTCAGAGCCCAGTGGAGTCGGATTTTCTCCACCGCACTCTTCGTGGAGCACGTGCTCCTAGGAACCGAGAGCCGCGTCCCCG
AGTTACAGGGGCTGGTGACCGAGCACGTCTTCTTACTAGACAAGTGTCTTCGAGAGAACTCTGACGTGAAGACGCACGGGCCTTTTGAGG
CCGTGATGCGCACTCTCTGTGAATGCAAGGAGACAGCCAGCAAGACCCTCAGCAGGTTTGGGATTCAGCCGTGCTCCATCTGCCTGGGAG
ATGCAAAGGACCCCGTCTGTCTGCCCTGCGACCACGTGCACTGCCTGCGCTGCCTCAGGGCCTGGTTTGCCTCAGAGCAGATGATATGCC
CCTACTGTTTAACTGCCTTGCCAGACGAATTCTCTCCAGCTGTTTCCCAAGCGCACAGGGAAGCCATTGAAAAGCATGCCCGCTTCCGGC
AGATGTGCAACAGTTTCTTCGTAGACCTGGTGTCCACCATTTGCTTCAAGGACAACGCTCCGCCTGAGAAGGAAGTGATTGAGAGCCTGC
TCTCTCTCCTCTTCGTCCAAAAGGGGCGCTTAAGAGATGCTGCCCAGAGACACTGTGAACACACAAAATCTCTCTCTCCATTCAATGATG
TTGTGGATAAGACTCCTGTCATCCGCTCAGTGATACTGAAACTGCTTTTGAAGTACAGCTTTCATGATGTAAAAGATTATATTCAGGAAT
ATTTGACCCTGTTAAAAAAGAAAGCATTCATAACTGAAGATAAAACTGAACTGTACATGCTCTTCATCAACTGCCTGGAGGATTCAATAC
TTGAGAAGACCAGTGCTTACTCCAGAAATGATGAACTGAACCACCTAGAAGAGGAAGGTCGTTTCCTTAAGGCATATTCTCCAGCAAGCC
GGGGCCGAGAGCCTGCCAACGAGGCCTCGGTTGAATACCTGCAAGAGGTGGCCCGGATCCGCCTCTGCCTCGACAGAGCTGCAGATTTCC
TCTCGGAGCCTGAGGGAGGCCCAGAGATGGCCAAGGAGAAGCAGTGCTACCTGCAGCAAGTCAAGCAGTTCTGTATCCGGGTGGAGAACG
ACTGGCACCGGGTGTACCTGGTGCGGAAGCTCAGCAGCCAGCGGGGGATGGAGTTCGTGCAGGGCCTCTCCAAGCCCGGCCGCCCGCACC
AGTGGGTGTTTCCCAAGGACGTTGTCAAGCAGCAGGGGCTGCGGCAGGACCACCCAGGCCAGATGGATAGGTACCTGGTGTACGGCGATG
AATACAAGGCTCTCCGTGATGCTGTGGCCAAAGCTGTCCTCGAGTGCAAGCCACTGGGCATTAAGACTGCTCTGAAGGCCTGCAAGACCC
CCCAAAGCCAGCAGTCAGCCTACTTCCTGTTAACACTGTTTAGAGAGGTGGCTATTTTGTACAGATCCCACAATGCAAGCCTCCACCCCA
CGCCAGAGCAATGTGAAGCTGTGAGCAAATTCATTGGCGAATGCAAGATCCTTTCACCTCCTGATATCAGCCGTTTTGCAACATCGCTCG
TGGACAATTCTGTGCCATTGTTGAGGGCGGGGCCTAGTGACAGCAACCTTGATGGAACGGTGACAGAAATGGCCATTCATGCTGCAGCCG
TCCTTCTGTGTGGACAGAATGAACTCTTGGAGCCCCTAAAGAATCTGGCCTTCTCCCCAGCCACCATGGCGCATGCTTTTCTTCCAACCA
TGCCTGAAGACTTGCTGGCTCAAGCTCGGAGGTGGAAGGGTCTGGAGCGAGTCCACTGGTACACTTGTCCCAACGGCCATCCTTGCTCCG
TGGGAGAGTGTGGCAGGCCGATGGAACAGAGCATCTGCATTGACTGCCATGCGCCGATTGGAGGCATTGACCACAAACCTCGGGACGGCT
TTCATCTGGTCAAAGACAAGGCAGACAGAACGCAGACCGGCCACGTGCTGGGCAACCCGCAGCGGAGAGACGTGGTGACATGTGACCGAG
GGCTGCCCCCAGTGGTCTTCCTCCTTATCCGGCTACTCACTCACTTGGCTCTGCTTCTGGGAGCGTCCCAGAGTTCCCAGATCAGTCGCA
TCGAATACATTCATTCAAAGAACTTCATCCACCGGGATGTGAAGCCAGACAACTTCCTCATGGGCCTGGGGAAGAAGGGCAACCTGGTGT
ACATCATCGACTTCGGGCTGGCCAAGAAGTACCGGGATGCACGCACCCACCAGCACATCCCCTATCGTGAGAACAAGAACCTCACGGGGA
CGGCGCGGTACGCCTCCATCAACACGCACCTTGGAATTGAACAATCCCGAAGAGATGACTTGGAGTCTCTGGGCTACGTGCTAATGTACT
TCAACCTGGGCTCTCTCCCCTGGCAGGGGCTGAAGGCTGCCACCAAGAGACAGAAATACGAAAGGATTAGCGAGAAGAAAATGTCCACCC
CCATCGAAGTGTTGTGTAAAGGCTACCCTTCCGAATTTGCCACATACCTGAATTTCTGCCGTTCCTTGCGTTTTGACGACAAGCCTGACT
ACTCGTACCTGCGGCAGCTTTTCCGGAATCTGTTCCATCGCCAGGGCTTCTCCTATGACTACGTGTTCGACTGGAACATGCTCAAATTTG
GTGCCAGCCGGGCCGCCGATGACGCCGAGCGGGAGCGCAGGGACCGAGAGGAGCGGCTGAGACACTCGCGGAACCCGGCTACCCGCGGCC
TCCCTTCCACAGCCTCCGGCCGCCTGCGGGGGACGCAGGAAGTGGCTCCCCCCACACCCCTCACCCCTACCTCACACACGGCTAACACCT
CCCCCCGGCCCGTCTCCGGCATGGAGAGAGAGCGGAAAGTGAGTATGCGGCTGCACCGCGGGGCCCCCGTCAACATCTCCTCGTCCGACC
TCACAGGCCGACAAGATACCTCTCGCATGTCCACCTCACAGATTCCTGGTCGGGTGGCTTCCAGTGGTCTTCAGTCTGTCGTGCACCGAT
GAGAACTCTCCTTATTGCTGTGAAGGGCAGACAATGCATGGCTGATCTACTCTGTTACCAATGGCTTTACTAGTGACACGTCCCCCGGTC
TAGGATCGAAATGTTAACACCGGGAGCTCTCCAGGCCACTCACCCAGCGACGCTCGTGGGGGAAACATACTAAACGGACAGACTCCAAGA
GCTGCCACCGCTGGGGCTGCACTGCGGCCCCCCACGTGAACTCGGTTGTAACGGGGCTGGGAAGAAAAGCAGAGAGAGAATTGCAGAGAA
TCAGACTCCTTTTCCAGGGCCTCAGCTCCCTCCAGTGGTGGCCGCCCTGTACTCCCTGACGATTCCACTGTAACTACCAATCTTCTACTT
GGTTAAGACAGTTTTGTATCATTTTGCTAAAAATTATTGGCTTAAATCTGTGTAAAGAAAATCTGTCTTTTTATTGTTTCTTGTCTGTTT
TTGCAGTCTTACAAAAAAAATGTTGACTAAGGAATTCTGAGACAGGCTGGCTTGGAGTTAGTGTATGAGGTGGAGTCGGGCAGGGAGAAG
GTGCAGGTGGATCTCAAGGGTGTGTGCTGTGTTTGTTTTGCAGTGTTTTATTGTCCGCTTTGGAGAGGAGATTTCTCATCAAAAGTCCGT
GGTGTGTGTGTGTGCCCGTGTGTGGTGGGACCTCTTCAACCTGATTTTGGCGTCTCACCCTCCCTCCTCCCGTAATTGACATGCCTGCTG
TCAGGAACTCTTGAGGCCCTCGGAGAGCAGTTAGGGACCGCAGGCTGCCGCGGGGCAGGGGTGCAGTGGGTGTTACCAGGCAAAGCACTG
CGCGCTTCTTCCCCAGGAGGTGGGCAGGCAGCTGAGAGCTTGGAAGCAGAGGCTTTGAGACCCTAGCAGGACAATTGGGAGTCCCAGGAT
TCAAGGTGGAAGATGCGTTTCTGGTCCCTTGGGAGAGGACTGTGAACCGAGAGGTGGTTACTGTAGTGTTTGTTGCCTTGCTGCCTTTGC
ACTCAGTCCATTTTCTCAGCACTCAATGCTCCTGTGCGGATTGGCACTCCGTCTGTATGAATGCCTGTGCTTAAAACCAGGAGCGGGGCT
GTCCTTGCCACGTGCCAAGACTAGCTCAGAAAAGCCGGCAGGCCAGAAGGACCCACCCTGAGGTGCCAAGGAGCAGGTGACTCTCCCAAC
CGGACCCAGAACCTTCACGGCCAGAAAGTAGAGTCTGCGCTGTGACCTTCTGTTGGGCGCGTGTCTGTTGGTCAGAAGTGAAGCAGCGTG
CGTGGGGCCGAGTCCCACCAGAAGGCAGGTGGCCTCCGTGAGCTGGTGCTGCCCCAGGCTCCATGCTGCTGTGCCCTGAGGTTCCCAGGA
TGCCTTCTCGCCTCTCACTCCGCAGCACTTGGGCGGTAGCCAGTGGCCATGTGCTCCCAACCCCAATGCGCAGGGCAGTCTGTGTTCGTG
GGCACTTCGGCTGGACCCCATCACGATGGACGATGTTCCCTTTGGACTCTAGGGCTTCGAAGGTGTGCACCTTGGTTCTCCCTTCTCCTC
CCCAGAGTTCCCCGGATGCCATAACTGGCTGGCGTCCCAGAACACAGTTGTTCACCCCCCCACCAGCTGGCTGGCCGTCTGCCTGAGCCC
ATGGATGCTTTCTCAATCCTAGGCTGGTTACTGTGTAAGCGTTTTGGAGTACGGGGCCTTGAGCGGGTGGGAGCTGTGTGTTGAAGTACA
GAGGGAGGTTGGGGTGGGTCAGAGCCGAGTTAAGAGATTTTCTTTGTTGCTGGACCCCTTCTTGAAGGTAGACGTCCCCCACCCGGAGAG
ACGTCGCGCTGTGGCCTGAAGTGGCGCAAGCTTGCTTTGTAAATATCTGTGGTCCCGATGTAGTGCCCAGAACGTTTGTGCGAGGCAGCT
CTGCGCCCGGGTTCCAGCCCGAGCCTCGCCGGGTCGCGTCTTCGGAGTGCTTGTGACAGTCCTTGCCCAGTATCTAGTCCCCGTCGCCCC
GTGCAGGAGACGTAGGTAGGACGTCGTGTCAGCTGTGCACTGACGGCCAGTCTCCGAGCTGTGCGTTTGTATCGCCACTGTATTTGTGTA

>74967_74967_7_RNF213-CSNK1D_RNF213_chr17_78354787_ENST00000582970_CSNK1D_chr17_80211120_ENST00000314028_length(amino acids)=4902AA_BP=4597
MECPSCQHVSKEETPKFCSQCGERLPPAAPIADSENNNSTMASASEGEMECGQELKEEGGPCLFPGSDSWQENPEEPCSKASWTVQESKK
KKRKKKKKGNKSASSELASLPLSPASPCHLTLLSNPWPQDTALPHSQAQQSGPTGQPSQPPGTATTPLEGDGLSAPTEVGDSPLQAQALG
EAGVATGSEAQSSPQFQDHTEGEDQDASIPSGGRGLSQEGTGPPTSAGEGHSRTEDAAQELLLPESKGGSSEPGTELQTTEQQAGASASM
AVDAVAEPANAVKGAGKEMKEKTQRMKQPPATTPPFKTHCQEAETKTKDEMAAAEEKVGKNEQGEPEDLKKPEGKNRSAAAVKNEKEQKN
QEADVQEVKASTLSPGGGVTVFFHAIISLHFPFNPDLHKVFIRGGEEFGESKWDSNICELHYTRDLGHDRVLVEGIVCISKKHLDKYIPY
KYVIYNGESFEYEFIYKHQQKKGEYVNRCLFIKSSLLGSGDWHQYYDIVYMKPHGRLQKVMNHITDGPRKDLVKGKQIAAALMLDSTFSI
LQTWDTINLNSFFTQFEQFCFVLQQPMIYEGQAQLWTDLQYREKEVKRYLWQHLKKHVVPLPDGKSTDFLPVDCPVRSKLKTGLIVLFVV
EKIELLLEGSLDWLCHLLTSDASSPDEFHRDLSHILGIPQSWRLYLVNLCQRCMDTRTYTWLGALPVLHCCMELAPRHKDAWRQPEDTWA
ALEGLSFSPFREQMLDTSSLLQFMREKQHLLSIDEPLFRSWFSLLPLSHLVMYMENFIEHLGRFPAHILDCLSGIYYRLPGLEQVLNTQD
VQDVQNVQNILEMLLRLLDTYRDKIPEEALSPSYLTVCLKLHEAICSSTKLLKFYELPALSAEIVCRMIRLLSLVDSAGQRDETGNNSVQ
TVFQGTLAATKRWLREVFTKNMLTSSGASFTYVKEIEVWRRLVEIQFPAEHGWKESLLGDMEWRLTKEEPLSQITAYCNSCWDTKGLEDS
VAKTFEKCIIEAVSSACQSQTSILQGFSYSDLRKFGIVLSAVITKSWPRTADNFNDILKHLLTLADVKHVFRLCGTDEKILANVTEDAKR
LIAVADSVLTKVVGDLLSGTILVGQLELIIKHKNQFLDIWQLREKSLSPQDEQCAVEEALDWRREELLLLKKEKRCVDSLLKMCGNVKHL
IQVDFGVLAVRHSQDLSSKRLNDTVTVRLSTSSNSQRATHYHLSSQVQEMAGKIDLLRDSHIFQLFWREAAEPLSEPKEDQEAAELLSEP
EEESERHILELEEVYDYLYQPSYRKFIKLHQDLKSGEVTLAEIDVIFKDFVNKYTDLDSELKIMCTVDHQDQRDWIKDRVEQIKEYHHLH
QAVHAAKVILQVKESLGLNGDFSVLNTLLNFTDNFDDFRRETLDQINQELIQAKKLLQDISEARCKGLQALSLRKEFICWVREALGGINE
LKVFVDLASISAGENDIDVDRVACFHDAVQGYASLLFKLDPSVDFSAFMKHLKKLWKALDKDQYLPRKLCDSARNLEWLKTVNESHGSVE
RSSLTLATAINQRGIYVIQAPKGGQKISPDTVLHLILPESPGSHEESREYSLEEVKELLNKLMLMSGKKDRNNTEVERFSEVFCSVQRLS
QAFIDLHSAGNMLFRTWIAMAYCSPKQGVSLQMDFGLDLVTELKEGGDVTELLAALCRQMEHFLDSWKRFVTQKRMEHFYLNFYTAEQLV
YLSTELRKQPPSDAALTMLSFIKSNCTLRDVLRASVGCGSEAARYRMRRVMEELPLMLLSEFSLVDKLRIIMEQSMRCLPAFLPDCLDLE
TLGHCLAHLAGMGGSPVERCLPRGLQVGQPNLVVCGHSEVLPAALAVYMQTPSQPLPTYDEVLLCTPATTFEEVALLLRRCLTLGSLGHK
VYSLLFADQLSYEVARQAEELFHNLCTQQHREDYQLVMVCDGDWEHCYLPSAFSQHKVFVTPQAPLEAIQAYLAGHYRVPKQTLSAAAVF
NDRLCVGIVASERAGVGKSLYVKRLHDKMKMQLNVKNVPLKTIRLIDPQVDESRVLGALLPFLDAQYQKVPVLFHLDVTSSVQTGIWVFL
FKLLILQYLMDINGKMWLRNPCHLYIVEILERRTSVPSRSSSALRTRVPQFSFLDIFPKVTCRPPKEVIDMELSALRSDTEPGMDLWEFC
SETFQRPYQYLRRFNQNQDLDTFQYQEGSVEGTPEECLQHFLFHCGVINPSWSELRNFARFLNYQLRDCEASLFCNPSFIGDTLRGFKKF
VVTFMIFMARDFATPSLHTSDQSPGKHMVTMDGVREEDLAPFSLRKRWESEPHPYVFFNDDHTTMTFIGFHLQPNINGSVDAISHLTGKV
IKRDVMTRDLYQGLLLQRVPFNVDFDKLPRHKKLERLCLTLGIPQATDPDKTYELTTDNMLKILAIEMRFRCGIPVIIMGETGCGKTRLI
KFLSDLRRGGTNADTIKLVKVHGGTTADMIYSRVREAENVAFANKDQHQLDTILFFDEANTTEAISCIKEVLCDHMVDGQPLAEDSGLHI
IAACNPYRKHSEEMICRLESAGLGYRVSMEETADRLGSIPLRQLVYRVHALPPSLIPLVWDFGQLSDVAEKLYIQQIVQRLVESISLDEN
GTRVITEVLCASQGFMRKTEDECSFVSLRDVERCVKVFRWFHEHSAMLLAQLNAFLSKSSVSKNHTERDPVLWSLMLAIGVCYHASLEKK
DSYRKAIARFFPKPYDDSRLLLDEITRAQDLFLDGVPLRKTIAKNLALKENVFMMVVCIELKIPLFLVGKPGSSKSLAKTIVADAMQGPA
AYSDLFRSLKQVHLVSFQCSPHSTPQGIISTFRQCARFQQGKDLQQYVSVVVLDEVGLAEDSPKMPLKTLHPLLEDGCIEDDPAPHKKVG
FVGISNWALDPAKMNRGIFVSRGSPNETELIESAKGICSSDILVQDRVQGYFASFAKAYETVCKRQDKEFFGLRDYYSLIKMVFAAAKAS
NRKPSPQDIAQAVLRNFSGKDDIQALDIFLANLPEAKCSEEVSPMQLIKQNIFGPSQKVPGGEQEDAESRYLLVLTKNYVALQILQQTFF
EGDQQPEIIFGSGFPKDQEYTQLCRNINRVKICMETGKMVLLLNLQNLYESLYDALNQYYVHLGGQKYVDLGLGTHRVKCRVHPNFRLIV
IEEKDVVYKHFPIPLINRLEKHYLDINTVLEKWQKSIVEELCAWVEKFINVKAHHFQKRHKYSPSDVFIGYHSDACASVVLQVIERQGPR
ALTEELHQKVSEEAKSILLNCATPDAVVRLSAYSLGGFAAEWLSQEYFHRQRHNSFADFLQAHLHTADLERHAIFTEITTFSRLLTSHDC
EILESEVTGRAPKPTLLWLQQFDTEYSFLKEVRNCLTNTAKCKILIFQTDFEDGIRSAQLIASAKYSVINEINKIRENEDRIFVYFITKL
SRVGRGTAYVGFHGGLWQSVHIDDLRRSTLMVSDVTRLQHVTISQLFAPGDLPELGLEHRAEDGHEEAMETEASTSGEVAEVAEEAMETE
SSEKVGKETSELGGSDVSILDTTRLLRSCVQSAVGMLRDQNESCTRNMRRVVLLLGLLNEDDACHASFLRVSKMRLSVFLKKQEESQFHP
LEWLAREACNQDALQEAGTFRHTLWKRVQGAVTPLLASMISFIDRDGNLELLTRPDTPPWARDLWMFIFSDTMLLNIPLVMNNERHKGEM
AYIVVQNHMNLSENASNNVPFSWKIKDYLEELWVQAQYITDAEGLPKKFVDIFQQTPLGRFLAQLHGEPQQELLQCYLKDFILLTMRVST
EEELKFLQMALWSCTRKLKAASEAPEEEVSLPWVHLAYQRFRSRLQNFSRILTIYPQVLHSLMEARWNHELAGCEMTLDAFAAMACTEML
TRNTLKPSPQAWLQLVKNLSMPLELICSDEHMQGSGSLAQAVIREVRAQWSRIFSTALFVEHVLLGTESRVPELQGLVTEHVFLLDKCLR
ENSDVKTHGPFEAVMRTLCECKETASKTLSRFGIQPCSICLGDAKDPVCLPCDHVHCLRCLRAWFASEQMICPYCLTALPDEFSPAVSQA
HREAIEKHARFRQMCNSFFVDLVSTICFKDNAPPEKEVIESLLSLLFVQKGRLRDAAQRHCEHTKSLSPFNDVVDKTPVIRSVILKLLLK
YSFHDVKDYIQEYLTLLKKKAFITEDKTELYMLFINCLEDSILEKTSAYSRNDELNHLEEEGRFLKAYSPASRGREPANEASVEYLQEVA
RIRLCLDRAADFLSEPEGGPEMAKEKQCYLQQVKQFCIRVENDWHRVYLVRKLSSQRGMEFVQGLSKPGRPHQWVFPKDVVKQQGLRQDH
PGQMDRYLVYGDEYKALRDAVAKAVLECKPLGIKTALKACKTPQSQQSAYFLLTLFREVAILYRSHNASLHPTPEQCEAVSKFIGECKIL
SPPDISRFATSLVDNSVPLLRAGPSDSNLDGTVTEMAIHAAAVLLCGQNELLEPLKNLAFSPATMAHAFLPTMPEDLLAQARRWKGLERV
HWYTCPNGHPCSVGECGRPMEQSICIDCHAPIGGIDHKPRDGFHLVKDKADRTQTGHVLGNPQRRDVVTCDRGLPPVVFLLIRLLTHLAL
LLGASQSSQISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRR
DDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFS
YDYVFDWNMLKFGASRAADDAERERRDREERLRHSRNPATRGLPSTASGRLRGTQEVAPPTPLTPTSHTANTSPRPVSGMERERKVSMRL

--------------------------------------------------------------
>74967_74967_8_RNF213-CSNK1D_RNF213_chr17_78354787_ENST00000582970_CSNK1D_chr17_80211120_ENST00000392334_length(transcript)=15335nt_BP=13940nt
CAGCGCGCGGCAGGCGGCGAGCTCGGGGGCCGCAGAAAATGAAACTGAAGCCGTGGTCACGTGACAGGACATGTAGTATATAGCAGGCTG
CCAGCGACTCCTGCTCTTGCTTCTGGATCTGCAGGGCAGTCCCAGCAGGACCCATGGAGTGTCCTTCGTGCCAGCATGTCTCCAAGGAGG
AAACCCCCAAGTTCTGCAGCCAGTGCGGAGAGAGGCTGCCTCCTGCAGCCCCCATAGCAGATTCTGAGAACAATAACTCCACAATGGCGT
CGGCCTCGGAGGGTGAAATGGAGTGTGGGCAGGAGCTGAAGGAGGAAGGGGGCCCGTGCTTGTTCCCGGGCTCAGACAGTTGGCAAGAAA
ACCCCGAGGAGCCCTGTTCCAAAGCCTCCTGGACCGTCCAAGAAAGCAAAAAGAAGAAAAGGAAGAAGAAAAAGAAGGGGAACAAGTCCG
CTTCCTCAGAGCTGGCTTCCTTGCCCCTTTCTCCTGCCAGCCCCTGTCACCTGACTTTGCTTTCAAACCCGTGGCCTCAGGACACAGCCC
TGCCCCACAGCCAAGCCCAGCAGAGTGGCCCCACTGGCCAGCCGAGCCAGCCCCCAGGCACAGCCACCACGCCACTGGAGGGTGACGGCC
TCTCCGCGCCCACCGAGGTTGGCGACAGCCCCCTGCAGGCCCAGGCTTTGGGAGAGGCAGGAGTGGCCACAGGAAGTGAGGCTCAGAGCA
GCCCGCAATTCCAGGACCACACGGAAGGGGAGGACCAGGACGCTTCCATCCCCTCTGGGGGCAGAGGCCTGTCCCAGGAGGGGACCGGTC
CCCCCACCTCTGCTGGTGAAGGCCATTCTAGGACTGAAGATGCTGCCCAGGAGCTCCTGTTGCCTGAGTCAAAAGGAGGCAGCTCTGAGC
CCGGGACAGAACTGCAGACCACCGAGCAACAGGCAGGGGCCTCAGCCTCTATGGCAGTTGATGCTGTAGCTGAGCCAGCCAATGCAGTTA
AAGGGGCCGGGAAGGAAATGAAAGAGAAGACCCAGAGAATGAAACAGCCACCAGCAACCACTCCTCCTTTCAAAACACACTGCCAGGAAG
CTGAGACCAAGACCAAGGACGAGATGGCTGCTGCTGAAGAAAAAGTCGGTAAGAATGAACAAGGGGAGCCTGAAGACCTCAAGAAGCCAG
AGGGGAAGAACAGAAGTGCAGCTGCTGTGAAAAACGAGAAGGAGCAAAAAAACCAGGAAGCAGATGTCCAGGAAGTGAAGGCAAGCACGC
TGAGCCCGGGTGGAGGAGTCACCGTGTTCTTCCACGCCATCATCTCTCTTCATTTCCCATTCAATCCTGACCTCCATAAAGTCTTCATCA
GAGGAGGAGAAGAATTTGGGGAGTCAAAATGGGACAGCAATATCTGTGAGCTGCACTACACCAGAGACTTGGGTCATGACCGCGTTCTTG
TTGAAGGCATTGTCTGCATTTCCAAGAAGCACCTAGATAAATACATTCCTTACAAGTACGTCATTTATAATGGGGAATCTTTTGAGTATG
AGTTCATTTACAAGCACCAGCAGAAGAAGGGCGAGTACGTCAACCGCTGTCTGTTCATAAAATCTTCACTTCTGGGCTCAGGAGACTGGC
ATCAGTACTATGACATAGTTTATATGAAGCCTCATGGGAGACTCCAGAAAGTCATGAACCACATCACAGACGGGCCGAGGAAGGACCTGG
TGAAGGGGAAGCAGATTGCCGCTGCGCTCATGCTGGACAGCACCTTCAGCATCCTGCAGACCTGGGACACCATCAACCTGAACAGCTTCT
TCACCCAGTTCGAGCAGTTTTGCTTTGTCCTGCAACAGCCTATGATTTATGAAGGACAGGCACAGCTGTGGACCGATTTGCAGTACAGGG
AGAAAGAGGTGAAGAGATACCTGTGGCAACATCTGAAAAAACACGTGGTACCATTGCCGGACGGAAAAAGCACGGACTTTTTGCCTGTGG
ACTGCCCAGTGAGGAGTAAACTGAAAACAGGCCTGATTGTCCTTTTTGTAGTGGAAAAAATTGAGCTTTTATTAGAAGGCAGCCTGGACT
GGTTGTGTCACCTCCTAACCTCAGATGCCAGCTCACCAGATGAGTTTCACCGTGACCTAAGCCACATCCTTGGGATACCTCAGAGCTGGC
GGCTGTACCTGGTGAACCTGTGCCAAAGATGCATGGACACAAGGACGTACACCTGGCTGGGCGCCCTGCCTGTCCTGCACTGCTGTATGG
AGCTGGCCCCGCGGCACAAGGATGCCTGGAGACAGCCTGAGGACACCTGGGCCGCTCTGGAGGGACTCTCCTTCTCACCGTTCCGGGAAC
AAATGCTAGATACGAGTTCCCTACTTCAGTTTATGAGAGAGAAGCAGCATTTGCTGAGCATAGACGAGCCTCTCTTCCGGTCCTGGTTTA
GTCTGCTACCTCTGAGTCACCTGGTTATGTATATGGAAAACTTCATTGAGCACCTGGGTCGTTTTCCTGCTCATATCCTGGACTGTCTTT
CAGGGATTTACTACCGGCTTCCGGGACTTGAGCAAGTCTTGAATACGCAGGATGTTCAGGATGTTCAGAACGTTCAGAACATTTTAGAAA
TGCTGTTGCGACTCCTGGACACTTACCGGGACAAGATTCCCGAGGAGGCCTTGTCACCATCCTACCTGACTGTGTGTCTGAAACTGCATG
AAGCCATCTGCAGCAGCACAAAGCTACTTAAGTTTTACGAGCTGCCAGCCTTATCTGCCGAGATTGTCTGCAGAATGATTAGACTTCTAT
CTCTGGTGGATTCTGCAGGACAGAGAGATGAAACTGGAAATAATTCAGTCCAAACAGTCTTCCAAGGGACCCTTGCTGCTACGAAAAGGT
GGCTCCGAGAAGTTTTTACAAAGAACATGCTCACATCTTCAGGTGCCTCATTCACATACGTCAAGGAAATTGAGGTCTGGAGGCGGCTGG
TGGAAATCCAATTCCCCGCGGAGCATGGCTGGAAGGAGTCGTTGCTGGGAGACATGGAATGGAGGCTCACAAAGGAGGAACCCCTCTCCC
AGATCACTGCCTACTGCAATAGTTGCTGGGACACCAAAGGCTTAGAGGACAGTGTGGCCAAGACCTTCGAGAAATGCATCATTGAAGCCG
TGAGCTCAGCCTGCCAGTCTCAGACCAGTATCCTTCAGGGGTTCTCTTACTCTGATTTGCGGAAATTTGGCATCGTCTTGTCTGCTGTGA
TCACTAAGTCCTGGCCTAGGACCGCGGACAACTTCAATGACATTTTAAAGCATCTGCTCACGTTGGCAGATGTCAAGCACGTCTTCAGAT
TGTGTGGAACCGACGAGAAAATACTAGCAAATGTCACAGAGGATGCCAAGAGGCTGATAGCTGTTGCCGACTCTGTGTTGACGAAAGTTG
TTGGTGACCTCCTAAGTGGCACGATTTTAGTTGGACAACTGGAGCTGATTATAAAGCACAAGAATCAGTTTCTTGACATCTGGCAACTGA
GGGAAAAAAGTCTTTCACCCCAGGATGAACAATGTGCTGTGGAGGAAGCACTGGATTGGAGAAGGGAGGAACTGTTACTTCTAAAGAAAG
AGAAAAGATGTGTTGATAGTCTCCTGAAGATGTGTGGGAACGTGAAACATCTGATACAAGTGGACTTTGGAGTGCTTGCAGTAAGACACT
CACAAGACCTCAGCAGTAAAAGATTAAATGACACCGTGACAGTGAGACTGTCCACCTCCTCGAACTCGCAGAGGGCAACGCATTACCACC
TGAGCTCCCAGGTCCAAGAAATGGCTGGGAAGATAGACTTGCTCAGAGACAGCCACATCTTCCAGCTCTTCTGGCGGGAAGCCGCAGAGC
CGCTGAGTGAGCCTAAGGAGGACCAGGAAGCCGCAGAGTTGCTGAGTGAGCCCGAAGAAGAATCAGAAAGGCACATCCTTGAGCTTGAAG
AGGTGTATGACTATTTGTATCAGCCTTCTTACAGAAAGTTCATTAAGTTGCACCAGGATCTAAAGTCAGGAGAGGTCACCCTTGCAGAGA
TTGATGTCATCTTCAAGGACTTTGTGAATAAATACACGGACCTGGATTCAGAACTTAAGATCATGTGCACCGTGGACCACCAGGACCAAA
GAGATTGGATCAAGGACCGAGTCGAACAGATCAAGGAATACCATCACCTGCACCAGGCTGTCCACGCAGCCAAGGTCATCTTGCAGGTCA
AAGAGAGCCTGGGACTGAACGGTGACTTCAGTGTTCTCAACACTTTACTAAATTTTACTGATAACTTCGACGACTTTCGCCGTGAAACAC
TGGACCAGATCAACCAGGAGCTCATCCAGGCCAAAAAGCTGCTCCAGGACATCAGCGAGGCCCGGTGCAAGGGGCTGCAGGCTCTGTCCC
TGAGAAAGGAGTTCATCTGCTGGGTCCGGGAGGCTCTTGGAGGCATCAATGAGCTGAAGGTGTTTGTGGACCTGGCCTCCATCTCAGCGG
GGGAGAATGACATTGATGTGGACCGGGTGGCCTGCTTCCATGACGCTGTGCAGGGCTACGCATCCCTGCTATTTAAGCTGGACCCCAGCG
TGGACTTCAGTGCATTCATGAAGCATCTGAAAAAGCTGTGGAAGGCTCTGGATAAGGACCAGTACCTGCCCAGGAAACTGTGTGACTCCG
CCAGGAACTTGGAATGGCTGAAGACTGTGAATGAGAGTCATGGGTCTGTGGAACGCTCATCCCTGACCCTGGCCACGGCCATCAACCAAA
GAGGCATCTATGTGATCCAGGCGCCCAAAGGTGGCCAAAAGATTTCCCCAGACACGGTTCTGCACTTGATCCTTCCTGAGAGCCCTGGCA
GCCACGAGGAGTCACGAGAGTACTCTTTAGAGGAGGTGAAGGAGCTTTTGAACAAGTTGATGCTGATGTCTGGCAAGAAGGATCGTAACA
ACACGGAAGTGGAGAGGTTTTCAGAGGTCTTCTGCAGTGTGCAGAGGCTCAGCCAGGCCTTCATCGACCTGCACTCTGCTGGGAATATGC
TGTTCAGGACGTGGATCGCCATGGCCTACTGCTCCCCCAAGCAGGGTGTGTCCCTCCAAATGGACTTTGGCTTGGACCTGGTGACGGAGC
TTAAAGAAGGTGGAGATGTCACTGAGCTGCTGGCAGCCCTCTGCAGGCAGATGGAGCACTTCCTTGACAGCTGGAAGAGATTTGTGACCC
AGAAGCGAATGGAGCACTTTTACCTGAACTTCTACACGGCAGAGCAGCTGGTTTACCTGAGCACTGAGCTCAGGAAGCAGCCCCCGAGTG
ATGCCGCCCTAACGATGCTATCCTTCATCAAAAGCAACTGCACCCTGAGGGATGTCTTAAGGGCCTCTGTGGGGTGTGGGAGTGAGGCCG
CCAGGTACCGCATGAGGAGAGTCATGGAAGAGCTCCCGCTGATGCTCTTATCAGAGTTCAGCCTGGTGGACAAGCTGAGGATCATCATGG
AGCAGTCCATGAGGTGCCTTCCTGCCTTCCTGCCCGACTGCCTCGACCTAGAGACCCTTGGCCACTGTCTGGCTCACCTGGCAGGGATGG
GTGGGTCTCCCGTGGAGCGTTGTCTCCCGAGAGGTCTGCAGGTCGGCCAGCCCAACCTCGTCGTCTGTGGCCACTCCGAGGTGTTGCCAG
CCGCCCTGGCTGTCTACATGCAAACCCCAAGCCAGCCCCTGCCCACTTACGATGAGGTGCTGCTCTGCACCCCGGCAACCACCTTTGAGG
AGGTGGCACTGTTGCTGCGCCGCTGCCTGACCCTGGGCTCCCTGGGGCACAAGGTCTACAGCCTGCTGTTCGCAGATCAGCTGAGCTACG
AGGTGGCACGCCAAGCGGAGGAGCTTTTCCACAATCTGTGCACGCAGCAGCACCGAGAAGACTACCAGCTCGTCATGGTCTGTGATGGGG
ACTGGGAGCACTGCTACCTCCCCTCTGCCTTCAGCCAGCACAAGGTCTTCGTCACCCCCCAGGCACCCCTCGAGGCCATCCAAGCCTACC
TGGCAGGTCACTACCGGGTCCCGAAGCAGACCCTGTCGGCGGCAGCCGTGTTCAATGACCGGCTGTGTGTTGGGATCGTGGCCTCGGAGC
GAGCAGGTGTTGGAAAGTCTCTGTACGTGAAGAGGTTGCACGACAAAATGAAGATGCAGTTAAACGTGAAAAATGTGCCTCTGAAAACAA
TTCGACTGATCGACCCTCAGGTGGATGAGAGCCGAGTCCTGGGCGCCCTGCTGCCCTTCCTGGATGCGCAGTATCAGAAGGTCCCCGTGC
TCTTTCACCTGGACGTGACCTCCTCAGTGCAGACTGGAATTTGGGTGTTTCTTTTCAAGCTCCTCATTTTACAATACTTAATGGATATAA
ATGGGAAAATGTGGCTTCGGAACCCCTGCCATTTGTATATCGTTGAAATCCTGGAAAGGAGGACGTCAGTGCCGTCGAGGAGCTCTTCAG
CGCTGCGTACACGTGTACCCCAGTTCAGTTTTCTTGACATCTTCCCAAAAGTCACCTGCAGGCCTCCCAAAGAGGTGATAGACATGGAGC
TGAGTGCCCTGAGGAGTGACACAGAGCCTGGGATGGATCTGTGGGAGTTCTGCAGCGAAACTTTCCAAAGACCTTACCAGTATTTAAGAC
GATTCAATCAAAACCAAGACCTAGACACGTTTCAGTATCAAGAAGGCTCTGTCGAAGGCACCCCGGAGGAATGCCTCCAGCATTTCCTGT
TTCACTGCGGGGTAATAAACCCATCCTGGTCAGAGCTTCGGAACTTTGCTCGGTTCCTGAATTATCAGCTCAGAGATTGTGAGGCCTCTC
TCTTCTGCAATCCGAGTTTTATTGGCGACACACTGAGGGGCTTCAAGAAGTTCGTGGTGACCTTCATGATCTTTATGGCAAGAGATTTTG
CCACACCATCACTCCACACCTCTGACCAAAGCCCGGGGAAGCACATGGTCACCATGGATGGGGTTAGGGAAGAAGATCTAGCGCCCTTCT
CCCTCCGGAAGAGGTGGGAGTCGGAGCCTCACCCATACGTTTTCTTCAATGACGACCACACAACCATGACATTCATCGGCTTCCATCTGC
AGCCCAACATCAACGGCAGTGTCGATGCCATCAGTCACTTGACTGGGAAGGTCATCAAGAGAGACGTCATGACCAGGGACCTGTACCAGG
GCCTGCTGCTCCAGAGGGTGCCCTTCAATGTCGACTTTGATAAACTGCCCAGACACAAGAAACTTGAGAGGCTCTGCCTGACCTTAGGGA
TCCCCCAGGCCACCGACCCCGACAAAACGTATGAGCTCACAACCGACAATATGCTTAAAATCCTTGCCATCGAGATGCGGTTCCGGTGTG
GGATCCCGGTTATCATCATGGGAGAAACTGGCTGTGGGAAAACCAGGCTTATTAAATTCCTTAGCGACCTGCGGCGTGGTGGTACCAATG
CTGACACCATAAAGCTGGTCAAGGTGCACGGAGGAACAACTGCAGACATGATCTACTCCAGAGTCAGGGAGGCTGAAAATGTGGCCTTCG
CCAATAAGGACCAACATCAGTTGGACACCATCTTGTTTTTTGATGAAGCCAACACAACGGAAGCTATAAGCTGTATCAAAGAAGTCCTGT
GTGATCATATGGTGGATGGCCAGCCTCTGGCTGAGGACTCTGGCCTGCATATTATAGCTGCCTGCAATCCATACCGGAAGCACTCTGAGG
AGATGATCTGCCGTTTGGAGTCAGCTGGTTTGGGCTACAGGGTTAGTATGGAGGAGACGGCCGACAGGCTGGGCTCCATTCCTCTGAGGC
AGCTGGTATACCGGGTCCATGCTCTGCCCCCGAGCCTGATTCCTCTGGTGTGGGACTTTGGACAACTGAGTGACGTTGCTGAAAAGCTCT
ACATCCAGCAGATTGTCCAGAGACTGGTTGAGTCCATCAGCCTAGATGAAAACGGGACTCGCGTGATCACAGAAGTCCTCTGCGCCTCTC
AGGGTTTCATGAGGAAAACAGAAGATGAGTGCAGCTTTGTCAGCCTCAGGGACGTGGAGCGCTGTGTGAAAGTTTTCAGGTGGTTCCACG
AGCACAGCGCGATGCTCTTAGCGCAGCTGAATGCCTTTCTCTCCAAGTCCAGCGTCAGCAAAAATCACACCGAGAGAGATCCCGTCCTCT
GGTCGTTGATGCTGGCCATCGGGGTGTGTTACCATGCCTCTTTAGAAAAGAAAGACTCATATCGGAAAGCCATCGCCAGGTTCTTTCCGA
AACCGTATGACGACAGCAGGCTGCTTCTGGATGAAATAACACGGGCACAGGATCTTTTTCTGGACGGCGTACCTCTGAGGAAAACCATCG
CCAAGAACTTGGCCTTGAAGGAGAACGTCTTCATGATGGTCGTCTGCATCGAGCTGAAGATTCCCCTCTTCCTGGTGGGGAAGCCCGGCA
GCTCCAAGTCTCTCGCCAAGACCATCGTGGCAGACGCCATGCAGGGCCCGGCTGCCTACTCAGATCTCTTCCGCAGCCTGAAGCAGGTCC
ACCTGGTGTCCTTCCAGTGCAGCCCGCACTCCACCCCACAGGGCATCATCAGCACCTTCCGGCAGTGCGCCCGCTTTCAGCAGGGGAAGG
ACCTGCAGCAGTACGTCTCTGTGGTGGTGTTAGATGAGGTGGGGCTGGCGGAAGACTCACCCAAAATGCCCCTGAAGACTCTGCACCCGC
TGCTGGAAGACGGATGCATTGAAGACGATCCCGCCCCCCACAAAAAGGTCGGCTTCGTGGGCATCTCCAACTGGGCCCTTGACCCTGCCA
AGATGAACCGGGGCATTTTTGTGTCACGTGGCAGCCCCAACGAGACAGAGCTCATAGAGAGCGCCAAGGGCATCTGCTCCTCAGACATCC
TCGTCCAGGACCGAGTCCAAGGGTACTTTGCGTCCTTTGCCAAAGCCTACGAAACGGTGTGTAAGCGCCAGGACAAGGAATTCTTCGGGC
TTCGTGACTACTACAGCCTCATCAAAATGGTCTTTGCTGCAGCAAAGGCTTCAAATAGAAAGCCTTCCCCGCAAGACATTGCACAGGCTG
TCCTTAGGAACTTCAGTGGCAAGGATGACATCCAAGCTTTGGACATCTTTCTGGCCAATTTGCCCGAGGCCAAGTGCTCAGAGGAAGTCA
GCCCCATGCAGCTGATCAAACAGAACATCTTTGGGCCTTCTCAGAAGGTGCCGGGTGGAGAGCAGGAAGATGCTGAGTCCCGCTACTTAC
TCGTGCTGACCAAAAACTACGTGGCACTGCAGATCCTGCAGCAGACATTCTTCGAGGGGGACCAGCAGCCGGAGATTATTTTTGGTTCTG
GTTTCCCCAAGGACCAAGAGTACACCCAGCTCTGCAGAAACATCAATCGTGTGAAGATCTGCATGGAAACAGGCAAGATGGTGTTGCTTC
TCAACCTGCAGAACCTCTACGAGAGCCTCTACGACGCACTCAACCAGTACTACGTCCACCTCGGCGGCCAGAAGTACGTGGACCTCGGTC
TGGGGACCCACCGCGTCAAATGTCGGGTTCACCCCAACTTCCGCCTGATTGTCATTGAAGAGAAAGACGTCGTGTACAAACACTTTCCCA
TCCCCCTCATTAACCGGCTGGAGAAGCACTATCTGGATATCAACACGGTGCTGGAGAAATGGCAGAAGAGCATCGTGGAGGAGCTCTGTG
CGTGGGTGGAGAAGTTCATCAATGTCAAAGCACATCATTTCCAGAAGAGGCACAAATACAGCCCCTCTGACGTCTTCATCGGCTACCACT
CGGACGCCTGCGCGTCTGTGGTGCTGCAGGTCATAGAGAGGCAGGGTCCCCGGGCCTTGACGGAGGAACTTCACCAGAAGGTGTCTGAGG
AGGCCAAATCGATCCTGCTGAACTGCGCTACGCCCGATGCCGTGGTCCGGCTGAGCGCCTACTCGCTGGGCGGGTTCGCAGCGGAGTGGC
TGTCGCAGGAGTACTTTCACAGACAGAGGCACAACTCCTTTGCAGATTTCCTTCAGGCACACCTGCACACGGCAGACCTGGAGCGCCACG
CCATCTTCACAGAGATCACCACTTTCTCCAGGCTGCTAACAAGTCACGACTGTGAAATTTTAGAATCAGAGGTCACAGGCAGGGCTCCGA
AACCCACACTCCTGTGGCTGCAGCAGTTTGACACCGAGTACTCATTCCTCAAAGAAGTCCGAAACTGTTTAACGAATACAGCCAAATGTA
AAATCCTCATTTTTCAGACAGATTTTGAAGATGGAATCCGTAGCGCCCAGCTCATTGCCTCAGCTAAGTATTCTGTTATAAATGAAATCA
ACAAAATACGAGAAAATGAGGACCGTATCTTCGTCTATTTCATCACAAAACTGTCCCGGGTGGGAAGAGGAACAGCCTATGTGGGCTTCC
ACGGAGGGCTGTGGCAGTCTGTCCACATCGATGACCTCCGGAGATCCACCCTCATGGTTTCTGATGTGACCAGGCTGCAGCATGTCACCA
TCAGCCAGCTGTTCGCGCCCGGAGACTTGCCTGAGCTGGGCTTGGAACACCGGGCGGAAGACGGCCATGAGGAGGCGATGGAGACGGAGG
CCAGCACATCAGGGGAGGTGGCAGAGGTGGCAGAGGAGGCCATGGAAACAGAAAGTTCTGAGAAGGTGGGAAAGGAAACCTCTGAACTCG
GAGGCAGTGATGTGTCGATCCTGGACACCACCAGGCTGCTGAGAAGCTGTGTGCAGAGCGCCGTGGGCATGCTCAGAGACCAGAACGAGA
GCTGCACGCGCAATATGCGGAGGGTGGTGCTCCTCCTGGGCCTCTTGAATGAGGATGACGCGTGCCACGCCTCTTTCTTGCGGGTATCCA
AGATGCGCCTCAGTGTCTTTTTAAAGAAGCAAGAAGAGAGCCAGTTTCACCCTCTGGAGTGGTTGGCAAGGGAAGCCTGCAACCAGGACG
CTCTCCAGGAGGCGGGCACATTCAGGCACACCCTCTGGAAGCGGGTCCAAGGTGCTGTCACCCCTCTGCTGGCGAGCATGATATCATTCA
TCGACAGAGACGGCAACCTAGAGTTACTGACCAGGCCAGATACTCCGCCCTGGGCAAGAGATCTTTGGATGTTTATTTTCAGTGACACGA
TGCTTCTGAACATTCCTCTTGTGATGAATAATGAAAGACATAAAGGTGAGATGGCCTACATCGTGGTGCAGAACCACATGAACCTTTCCG
AGAACGCTTCCAACAACGTCCCTTTCAGCTGGAAAATCAAGGACTATCTGGAGGAGCTGTGGGTCCAGGCTCAGTACATCACAGACGCAG
AAGGACTGCCCAAGAAGTTCGTGGACATCTTTCAGCAGACTCCTCTGGGCAGGTTTCTTGCCCAGCTCCATGGAGAGCCGCAGCAGGAAC
TTCTTCAGTGTTACTTGAAGGATTTCATTCTCTTGACCATGCGTGTGTCAACGGAGGAGGAATTAAAGTTTCTGCAGATGGCTCTGTGGT
CCTGCACTAGGAAACTGAAAGCGGCGTCAGAAGCGCCCGAGGAAGAGGTTTCCTTACCGTGGGTGCACCTTGCCTACCAGCGTTTCAGAA
GCCGTCTGCAGAACTTTTCCAGAATCCTGACCATCTACCCTCAGGTTCTCCACAGCCTGATGGAAGCCCGTTGGAACCATGAGCTGGCTG
GATGTGAGATGACCCTGGACGCATTTGCCGCAATGGCCTGCACGGAGATGCTGACAAGAAACACCCTGAAGCCCAGTCCCCAGGCGTGGC
TACAGTTGGTGAAGAATCTTTCCATGCCGCTGGAGCTCATCTGCTCCGATGAGCACATGCAAGGCAGCGGGAGCCTGGCCCAGGCTGTCA
TCAGGGAAGTCAGAGCCCAGTGGAGTCGGATTTTCTCCACCGCACTCTTCGTGGAGCACGTGCTCCTAGGAACCGAGAGCCGCGTCCCCG
AGTTACAGGGGCTGGTGACCGAGCACGTCTTCTTACTAGACAAGTGTCTTCGAGAGAACTCTGACGTGAAGACGCACGGGCCTTTTGAGG
CCGTGATGCGCACTCTCTGTGAATGCAAGGAGACAGCCAGCAAGACCCTCAGCAGGTTTGGGATTCAGCCGTGCTCCATCTGCCTGGGAG
ATGCAAAGGACCCCGTCTGTCTGCCCTGCGACCACGTGCACTGCCTGCGCTGCCTCAGGGCCTGGTTTGCCTCAGAGCAGATGATATGCC
CCTACTGTTTAACTGCCTTGCCAGACGAATTCTCTCCAGCTGTTTCCCAAGCGCACAGGGAAGCCATTGAAAAGCATGCCCGCTTCCGGC
AGATGTGCAACAGTTTCTTCGTAGACCTGGTGTCCACCATTTGCTTCAAGGACAACGCTCCGCCTGAGAAGGAAGTGATTGAGAGCCTGC
TCTCTCTCCTCTTCGTCCAAAAGGGGCGCTTAAGAGATGCTGCCCAGAGACACTGTGAACACACAAAATCTCTCTCTCCATTCAATGATG
TTGTGGATAAGACTCCTGTCATCCGCTCAGTGATACTGAAACTGCTTTTGAAGTACAGCTTTCATGATGTAAAAGATTATATTCAGGAAT
ATTTGACCCTGTTAAAAAAGAAAGCATTCATAACTGAAGATAAAACTGAACTGTACATGCTCTTCATCAACTGCCTGGAGGATTCAATAC
TTGAGAAGACCAGTGCTTACTCCAGAAATGATGAACTGAACCACCTAGAAGAGGAAGGTCGTTTCCTTAAGGCATATTCTCCAGCAAGCC
GGGGCCGAGAGCCTGCCAACGAGGCCTCGGTTGAATACCTGCAAGAGGTGGCCCGGATCCGCCTCTGCCTCGACAGAGCTGCAGATTTCC
TCTCGGAGCCTGAGGGAGGCCCAGAGATGGCCAAGGAGAAGCAGTGCTACCTGCAGCAAGTCAAGCAGTTCTGTATCCGGGTGGAGAACG
ACTGGCACCGGGTGTACCTGGTGCGGAAGCTCAGCAGCCAGCGGGGGATGGAGTTCGTGCAGGGCCTCTCCAAGCCCGGCCGCCCGCACC
AGTGGGTGTTTCCCAAGGACGTTGTCAAGCAGCAGGGGCTGCGGCAGGACCACCCAGGCCAGATGGATAGGTACCTGGTGTACGGCGATG
AATACAAGGCTCTCCGTGATGCTGTGGCCAAAGCTGTCCTCGAGTGCAAGCCACTGGGCATTAAGACTGCTCTGAAGGCCTGCAAGACCC
CCCAAAGCCAGCAGTCAGCCTACTTCCTGTTAACACTGTTTAGAGAGGTGGCTATTTTGTACAGATCCCACAATGCAAGCCTCCACCCCA
CGCCAGAGCAATGTGAAGCTGTGAGCAAATTCATTGGCGAATGCAAGATCCTTTCACCTCCTGATATCAGCCGTTTTGCAACATCGCTCG
TGGACAATTCTGTGCCATTGTTGAGGGCGGGGCCTAGTGACAGCAACCTTGATGGAACGGTGACAGAAATGGCCATTCATGCTGCAGCCG
TCCTTCTGTGTGGACAGAATGAACTCTTGGAGCCCCTAAAGAATCTGGCCTTCTCCCCAGCCACCATGGCGCATGCTTTTCTTCCAACCA
TGCCTGAAGACTTGCTGGCTCAAGCTCGGAGGTGGAAGGGTCTGGAGCGAGTCCACTGGTACACTTGTCCCAACGGCCATCCTTGCTCCG
TGGGAGAGTGTGGCAGGCCGATGGAACAGAGCATCTGCATTGACTGCCATGCGCCGATTGGAGGCATTGACCACAAACCTCGGGACGGCT
TTCATCTGGTCAAAGACAAGGCAGACAGAACGCAGACCGGCCACGTGCTGGGCAACCCGCAGCGGAGAGACGTGGTGACATGTGACCGAG
GGCTGCCCCCAGTGGTCTTCCTCCTTATCCGGCTACTCACTCACTTGGCTCTGCTTCTGGGAGCGTCCCAGAGTTCCCAGATCAGTCGCA
TCGAATACATTCATTCAAAGAACTTCATCCACCGGGATGTGAAGCCAGACAACTTCCTCATGGGCCTGGGGAAGAAGGGCAACCTGGTGT
ACATCATCGACTTCGGGCTGGCCAAGAAGTACCGGGATGCACGCACCCACCAGCACATCCCCTATCGTGAGAACAAGAACCTCACGGGGA
CGGCGCGGTACGCCTCCATCAACACGCACCTTGGAATTGAACAATCCCGAAGAGATGACTTGGAGTCTCTGGGCTACGTGCTAATGTACT
TCAACCTGGGCTCTCTCCCCTGGCAGGGGCTGAAGGCTGCCACCAAGAGACAGAAATACGAAAGGATTAGCGAGAAGAAAATGTCCACCC
CCATCGAAGTGTTGTGTAAAGGCTACCCTTCCGAATTTGCCACATACCTGAATTTCTGCCGTTCCTTGCGTTTTGACGACAAGCCTGACT
ACTCGTACCTGCGGCAGCTTTTCCGGAATCTGTTCCATCGCCAGGGCTTCTCCTATGACTACGTGTTCGACTGGAACATGCTCAAATTTG
GTGCCAGCCGGGCCGCCGATGACGCCGAGCGGGAGCGCAGGGACCGAGAGGAGCGGCTGAGACACTCGCGGAACCCGGCTACCCGCGGCC
TCCCTTCCACAGCCTCCGGCCGCCTGCGGGGGACGCAGGAAGTGGCTCCCCCCACACCCCTCACCCCTACCTCACACACGGCTAACACCT
CCCCCCGGCCCGTCTCCGGCATGGAGAGAGAGCGGAAAGTGAGTATGCGGCTGCACCGCGGGGCCCCCGTCAACATCTCCTCGTCCGACC
TCACAGGCCGACAAGATACCTCTCGCATGTCCACCTCACAGAATAGCATTCCTTTCGAACACCACGGCAAGTAGCTGCTCGTCTCCCATC
GGAAGGCAGCACTGGATTCCTGGTCGGGTGGCTTCCAGTGGTCTTCAGTCTGTCGTGCACCGATGAGAACTCTCCTTATTGCTGTGAAGG
GCAGACAATGCATGGCTGATCTACTCTGTTACCAATGGCTTTACTAGTGACACGTCCCCCGGTCTAGGATCGAAATGTTAACACCGGGAG
CTCTCCAGGCCACTCACCCAGCGACGCTCGTGGGGGAAACATACTAAACGGACAGACTCCAAGAGCTGCCACCGCTGGGGCTGCACTGCG
GCCCCCCACGTGAACTCGGTTGTAACGGGGCTGGGAAGAAAAGCAGAGAGAGAATTGCAGAGAATCAGACTCCTTTTCCAGGGCCTCAGC
TCCCTCCAGTGGTGGCCGCCCTGTACTCCCTGACGATTCCACTGTAACTACCAATCTTCTACTTGGTTAAGACAGTTTTGTATCATTTTG

>74967_74967_8_RNF213-CSNK1D_RNF213_chr17_78354787_ENST00000582970_CSNK1D_chr17_80211120_ENST00000392334_length(amino acids)=4896AA_BP=4597
MECPSCQHVSKEETPKFCSQCGERLPPAAPIADSENNNSTMASASEGEMECGQELKEEGGPCLFPGSDSWQENPEEPCSKASWTVQESKK
KKRKKKKKGNKSASSELASLPLSPASPCHLTLLSNPWPQDTALPHSQAQQSGPTGQPSQPPGTATTPLEGDGLSAPTEVGDSPLQAQALG
EAGVATGSEAQSSPQFQDHTEGEDQDASIPSGGRGLSQEGTGPPTSAGEGHSRTEDAAQELLLPESKGGSSEPGTELQTTEQQAGASASM
AVDAVAEPANAVKGAGKEMKEKTQRMKQPPATTPPFKTHCQEAETKTKDEMAAAEEKVGKNEQGEPEDLKKPEGKNRSAAAVKNEKEQKN
QEADVQEVKASTLSPGGGVTVFFHAIISLHFPFNPDLHKVFIRGGEEFGESKWDSNICELHYTRDLGHDRVLVEGIVCISKKHLDKYIPY
KYVIYNGESFEYEFIYKHQQKKGEYVNRCLFIKSSLLGSGDWHQYYDIVYMKPHGRLQKVMNHITDGPRKDLVKGKQIAAALMLDSTFSI
LQTWDTINLNSFFTQFEQFCFVLQQPMIYEGQAQLWTDLQYREKEVKRYLWQHLKKHVVPLPDGKSTDFLPVDCPVRSKLKTGLIVLFVV
EKIELLLEGSLDWLCHLLTSDASSPDEFHRDLSHILGIPQSWRLYLVNLCQRCMDTRTYTWLGALPVLHCCMELAPRHKDAWRQPEDTWA
ALEGLSFSPFREQMLDTSSLLQFMREKQHLLSIDEPLFRSWFSLLPLSHLVMYMENFIEHLGRFPAHILDCLSGIYYRLPGLEQVLNTQD
VQDVQNVQNILEMLLRLLDTYRDKIPEEALSPSYLTVCLKLHEAICSSTKLLKFYELPALSAEIVCRMIRLLSLVDSAGQRDETGNNSVQ
TVFQGTLAATKRWLREVFTKNMLTSSGASFTYVKEIEVWRRLVEIQFPAEHGWKESLLGDMEWRLTKEEPLSQITAYCNSCWDTKGLEDS
VAKTFEKCIIEAVSSACQSQTSILQGFSYSDLRKFGIVLSAVITKSWPRTADNFNDILKHLLTLADVKHVFRLCGTDEKILANVTEDAKR
LIAVADSVLTKVVGDLLSGTILVGQLELIIKHKNQFLDIWQLREKSLSPQDEQCAVEEALDWRREELLLLKKEKRCVDSLLKMCGNVKHL
IQVDFGVLAVRHSQDLSSKRLNDTVTVRLSTSSNSQRATHYHLSSQVQEMAGKIDLLRDSHIFQLFWREAAEPLSEPKEDQEAAELLSEP
EEESERHILELEEVYDYLYQPSYRKFIKLHQDLKSGEVTLAEIDVIFKDFVNKYTDLDSELKIMCTVDHQDQRDWIKDRVEQIKEYHHLH
QAVHAAKVILQVKESLGLNGDFSVLNTLLNFTDNFDDFRRETLDQINQELIQAKKLLQDISEARCKGLQALSLRKEFICWVREALGGINE
LKVFVDLASISAGENDIDVDRVACFHDAVQGYASLLFKLDPSVDFSAFMKHLKKLWKALDKDQYLPRKLCDSARNLEWLKTVNESHGSVE
RSSLTLATAINQRGIYVIQAPKGGQKISPDTVLHLILPESPGSHEESREYSLEEVKELLNKLMLMSGKKDRNNTEVERFSEVFCSVQRLS
QAFIDLHSAGNMLFRTWIAMAYCSPKQGVSLQMDFGLDLVTELKEGGDVTELLAALCRQMEHFLDSWKRFVTQKRMEHFYLNFYTAEQLV
YLSTELRKQPPSDAALTMLSFIKSNCTLRDVLRASVGCGSEAARYRMRRVMEELPLMLLSEFSLVDKLRIIMEQSMRCLPAFLPDCLDLE
TLGHCLAHLAGMGGSPVERCLPRGLQVGQPNLVVCGHSEVLPAALAVYMQTPSQPLPTYDEVLLCTPATTFEEVALLLRRCLTLGSLGHK
VYSLLFADQLSYEVARQAEELFHNLCTQQHREDYQLVMVCDGDWEHCYLPSAFSQHKVFVTPQAPLEAIQAYLAGHYRVPKQTLSAAAVF
NDRLCVGIVASERAGVGKSLYVKRLHDKMKMQLNVKNVPLKTIRLIDPQVDESRVLGALLPFLDAQYQKVPVLFHLDVTSSVQTGIWVFL
FKLLILQYLMDINGKMWLRNPCHLYIVEILERRTSVPSRSSSALRTRVPQFSFLDIFPKVTCRPPKEVIDMELSALRSDTEPGMDLWEFC
SETFQRPYQYLRRFNQNQDLDTFQYQEGSVEGTPEECLQHFLFHCGVINPSWSELRNFARFLNYQLRDCEASLFCNPSFIGDTLRGFKKF
VVTFMIFMARDFATPSLHTSDQSPGKHMVTMDGVREEDLAPFSLRKRWESEPHPYVFFNDDHTTMTFIGFHLQPNINGSVDAISHLTGKV
IKRDVMTRDLYQGLLLQRVPFNVDFDKLPRHKKLERLCLTLGIPQATDPDKTYELTTDNMLKILAIEMRFRCGIPVIIMGETGCGKTRLI
KFLSDLRRGGTNADTIKLVKVHGGTTADMIYSRVREAENVAFANKDQHQLDTILFFDEANTTEAISCIKEVLCDHMVDGQPLAEDSGLHI
IAACNPYRKHSEEMICRLESAGLGYRVSMEETADRLGSIPLRQLVYRVHALPPSLIPLVWDFGQLSDVAEKLYIQQIVQRLVESISLDEN
GTRVITEVLCASQGFMRKTEDECSFVSLRDVERCVKVFRWFHEHSAMLLAQLNAFLSKSSVSKNHTERDPVLWSLMLAIGVCYHASLEKK
DSYRKAIARFFPKPYDDSRLLLDEITRAQDLFLDGVPLRKTIAKNLALKENVFMMVVCIELKIPLFLVGKPGSSKSLAKTIVADAMQGPA
AYSDLFRSLKQVHLVSFQCSPHSTPQGIISTFRQCARFQQGKDLQQYVSVVVLDEVGLAEDSPKMPLKTLHPLLEDGCIEDDPAPHKKVG
FVGISNWALDPAKMNRGIFVSRGSPNETELIESAKGICSSDILVQDRVQGYFASFAKAYETVCKRQDKEFFGLRDYYSLIKMVFAAAKAS
NRKPSPQDIAQAVLRNFSGKDDIQALDIFLANLPEAKCSEEVSPMQLIKQNIFGPSQKVPGGEQEDAESRYLLVLTKNYVALQILQQTFF
EGDQQPEIIFGSGFPKDQEYTQLCRNINRVKICMETGKMVLLLNLQNLYESLYDALNQYYVHLGGQKYVDLGLGTHRVKCRVHPNFRLIV
IEEKDVVYKHFPIPLINRLEKHYLDINTVLEKWQKSIVEELCAWVEKFINVKAHHFQKRHKYSPSDVFIGYHSDACASVVLQVIERQGPR
ALTEELHQKVSEEAKSILLNCATPDAVVRLSAYSLGGFAAEWLSQEYFHRQRHNSFADFLQAHLHTADLERHAIFTEITTFSRLLTSHDC
EILESEVTGRAPKPTLLWLQQFDTEYSFLKEVRNCLTNTAKCKILIFQTDFEDGIRSAQLIASAKYSVINEINKIRENEDRIFVYFITKL
SRVGRGTAYVGFHGGLWQSVHIDDLRRSTLMVSDVTRLQHVTISQLFAPGDLPELGLEHRAEDGHEEAMETEASTSGEVAEVAEEAMETE
SSEKVGKETSELGGSDVSILDTTRLLRSCVQSAVGMLRDQNESCTRNMRRVVLLLGLLNEDDACHASFLRVSKMRLSVFLKKQEESQFHP
LEWLAREACNQDALQEAGTFRHTLWKRVQGAVTPLLASMISFIDRDGNLELLTRPDTPPWARDLWMFIFSDTMLLNIPLVMNNERHKGEM
AYIVVQNHMNLSENASNNVPFSWKIKDYLEELWVQAQYITDAEGLPKKFVDIFQQTPLGRFLAQLHGEPQQELLQCYLKDFILLTMRVST
EEELKFLQMALWSCTRKLKAASEAPEEEVSLPWVHLAYQRFRSRLQNFSRILTIYPQVLHSLMEARWNHELAGCEMTLDAFAAMACTEML
TRNTLKPSPQAWLQLVKNLSMPLELICSDEHMQGSGSLAQAVIREVRAQWSRIFSTALFVEHVLLGTESRVPELQGLVTEHVFLLDKCLR
ENSDVKTHGPFEAVMRTLCECKETASKTLSRFGIQPCSICLGDAKDPVCLPCDHVHCLRCLRAWFASEQMICPYCLTALPDEFSPAVSQA
HREAIEKHARFRQMCNSFFVDLVSTICFKDNAPPEKEVIESLLSLLFVQKGRLRDAAQRHCEHTKSLSPFNDVVDKTPVIRSVILKLLLK
YSFHDVKDYIQEYLTLLKKKAFITEDKTELYMLFINCLEDSILEKTSAYSRNDELNHLEEEGRFLKAYSPASRGREPANEASVEYLQEVA
RIRLCLDRAADFLSEPEGGPEMAKEKQCYLQQVKQFCIRVENDWHRVYLVRKLSSQRGMEFVQGLSKPGRPHQWVFPKDVVKQQGLRQDH
PGQMDRYLVYGDEYKALRDAVAKAVLECKPLGIKTALKACKTPQSQQSAYFLLTLFREVAILYRSHNASLHPTPEQCEAVSKFIGECKIL
SPPDISRFATSLVDNSVPLLRAGPSDSNLDGTVTEMAIHAAAVLLCGQNELLEPLKNLAFSPATMAHAFLPTMPEDLLAQARRWKGLERV
HWYTCPNGHPCSVGECGRPMEQSICIDCHAPIGGIDHKPRDGFHLVKDKADRTQTGHVLGNPQRRDVVTCDRGLPPVVFLLIRLLTHLAL
LLGASQSSQISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRR
DDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFS
YDYVFDWNMLKFGASRAADDAERERRDREERLRHSRNPATRGLPSTASGRLRGTQEVAPPTPLTPTSHTANTSPRPVSGMERERKVSMRL

--------------------------------------------------------------
>74967_74967_9_RNF213-CSNK1D_RNF213_chr17_78354787_ENST00000582970_CSNK1D_chr17_80211120_ENST00000398519_length(transcript)=15137nt_BP=13940nt
CAGCGCGCGGCAGGCGGCGAGCTCGGGGGCCGCAGAAAATGAAACTGAAGCCGTGGTCACGTGACAGGACATGTAGTATATAGCAGGCTG
CCAGCGACTCCTGCTCTTGCTTCTGGATCTGCAGGGCAGTCCCAGCAGGACCCATGGAGTGTCCTTCGTGCCAGCATGTCTCCAAGGAGG
AAACCCCCAAGTTCTGCAGCCAGTGCGGAGAGAGGCTGCCTCCTGCAGCCCCCATAGCAGATTCTGAGAACAATAACTCCACAATGGCGT
CGGCCTCGGAGGGTGAAATGGAGTGTGGGCAGGAGCTGAAGGAGGAAGGGGGCCCGTGCTTGTTCCCGGGCTCAGACAGTTGGCAAGAAA
ACCCCGAGGAGCCCTGTTCCAAAGCCTCCTGGACCGTCCAAGAAAGCAAAAAGAAGAAAAGGAAGAAGAAAAAGAAGGGGAACAAGTCCG
CTTCCTCAGAGCTGGCTTCCTTGCCCCTTTCTCCTGCCAGCCCCTGTCACCTGACTTTGCTTTCAAACCCGTGGCCTCAGGACACAGCCC
TGCCCCACAGCCAAGCCCAGCAGAGTGGCCCCACTGGCCAGCCGAGCCAGCCCCCAGGCACAGCCACCACGCCACTGGAGGGTGACGGCC
TCTCCGCGCCCACCGAGGTTGGCGACAGCCCCCTGCAGGCCCAGGCTTTGGGAGAGGCAGGAGTGGCCACAGGAAGTGAGGCTCAGAGCA
GCCCGCAATTCCAGGACCACACGGAAGGGGAGGACCAGGACGCTTCCATCCCCTCTGGGGGCAGAGGCCTGTCCCAGGAGGGGACCGGTC
CCCCCACCTCTGCTGGTGAAGGCCATTCTAGGACTGAAGATGCTGCCCAGGAGCTCCTGTTGCCTGAGTCAAAAGGAGGCAGCTCTGAGC
CCGGGACAGAACTGCAGACCACCGAGCAACAGGCAGGGGCCTCAGCCTCTATGGCAGTTGATGCTGTAGCTGAGCCAGCCAATGCAGTTA
AAGGGGCCGGGAAGGAAATGAAAGAGAAGACCCAGAGAATGAAACAGCCACCAGCAACCACTCCTCCTTTCAAAACACACTGCCAGGAAG
CTGAGACCAAGACCAAGGACGAGATGGCTGCTGCTGAAGAAAAAGTCGGTAAGAATGAACAAGGGGAGCCTGAAGACCTCAAGAAGCCAG
AGGGGAAGAACAGAAGTGCAGCTGCTGTGAAAAACGAGAAGGAGCAAAAAAACCAGGAAGCAGATGTCCAGGAAGTGAAGGCAAGCACGC
TGAGCCCGGGTGGAGGAGTCACCGTGTTCTTCCACGCCATCATCTCTCTTCATTTCCCATTCAATCCTGACCTCCATAAAGTCTTCATCA
GAGGAGGAGAAGAATTTGGGGAGTCAAAATGGGACAGCAATATCTGTGAGCTGCACTACACCAGAGACTTGGGTCATGACCGCGTTCTTG
TTGAAGGCATTGTCTGCATTTCCAAGAAGCACCTAGATAAATACATTCCTTACAAGTACGTCATTTATAATGGGGAATCTTTTGAGTATG
AGTTCATTTACAAGCACCAGCAGAAGAAGGGCGAGTACGTCAACCGCTGTCTGTTCATAAAATCTTCACTTCTGGGCTCAGGAGACTGGC
ATCAGTACTATGACATAGTTTATATGAAGCCTCATGGGAGACTCCAGAAAGTCATGAACCACATCACAGACGGGCCGAGGAAGGACCTGG
TGAAGGGGAAGCAGATTGCCGCTGCGCTCATGCTGGACAGCACCTTCAGCATCCTGCAGACCTGGGACACCATCAACCTGAACAGCTTCT
TCACCCAGTTCGAGCAGTTTTGCTTTGTCCTGCAACAGCCTATGATTTATGAAGGACAGGCACAGCTGTGGACCGATTTGCAGTACAGGG
AGAAAGAGGTGAAGAGATACCTGTGGCAACATCTGAAAAAACACGTGGTACCATTGCCGGACGGAAAAAGCACGGACTTTTTGCCTGTGG
ACTGCCCAGTGAGGAGTAAACTGAAAACAGGCCTGATTGTCCTTTTTGTAGTGGAAAAAATTGAGCTTTTATTAGAAGGCAGCCTGGACT
GGTTGTGTCACCTCCTAACCTCAGATGCCAGCTCACCAGATGAGTTTCACCGTGACCTAAGCCACATCCTTGGGATACCTCAGAGCTGGC
GGCTGTACCTGGTGAACCTGTGCCAAAGATGCATGGACACAAGGACGTACACCTGGCTGGGCGCCCTGCCTGTCCTGCACTGCTGTATGG
AGCTGGCCCCGCGGCACAAGGATGCCTGGAGACAGCCTGAGGACACCTGGGCCGCTCTGGAGGGACTCTCCTTCTCACCGTTCCGGGAAC
AAATGCTAGATACGAGTTCCCTACTTCAGTTTATGAGAGAGAAGCAGCATTTGCTGAGCATAGACGAGCCTCTCTTCCGGTCCTGGTTTA
GTCTGCTACCTCTGAGTCACCTGGTTATGTATATGGAAAACTTCATTGAGCACCTGGGTCGTTTTCCTGCTCATATCCTGGACTGTCTTT
CAGGGATTTACTACCGGCTTCCGGGACTTGAGCAAGTCTTGAATACGCAGGATGTTCAGGATGTTCAGAACGTTCAGAACATTTTAGAAA
TGCTGTTGCGACTCCTGGACACTTACCGGGACAAGATTCCCGAGGAGGCCTTGTCACCATCCTACCTGACTGTGTGTCTGAAACTGCATG
AAGCCATCTGCAGCAGCACAAAGCTACTTAAGTTTTACGAGCTGCCAGCCTTATCTGCCGAGATTGTCTGCAGAATGATTAGACTTCTAT
CTCTGGTGGATTCTGCAGGACAGAGAGATGAAACTGGAAATAATTCAGTCCAAACAGTCTTCCAAGGGACCCTTGCTGCTACGAAAAGGT
GGCTCCGAGAAGTTTTTACAAAGAACATGCTCACATCTTCAGGTGCCTCATTCACATACGTCAAGGAAATTGAGGTCTGGAGGCGGCTGG
TGGAAATCCAATTCCCCGCGGAGCATGGCTGGAAGGAGTCGTTGCTGGGAGACATGGAATGGAGGCTCACAAAGGAGGAACCCCTCTCCC
AGATCACTGCCTACTGCAATAGTTGCTGGGACACCAAAGGCTTAGAGGACAGTGTGGCCAAGACCTTCGAGAAATGCATCATTGAAGCCG
TGAGCTCAGCCTGCCAGTCTCAGACCAGTATCCTTCAGGGGTTCTCTTACTCTGATTTGCGGAAATTTGGCATCGTCTTGTCTGCTGTGA
TCACTAAGTCCTGGCCTAGGACCGCGGACAACTTCAATGACATTTTAAAGCATCTGCTCACGTTGGCAGATGTCAAGCACGTCTTCAGAT
TGTGTGGAACCGACGAGAAAATACTAGCAAATGTCACAGAGGATGCCAAGAGGCTGATAGCTGTTGCCGACTCTGTGTTGACGAAAGTTG
TTGGTGACCTCCTAAGTGGCACGATTTTAGTTGGACAACTGGAGCTGATTATAAAGCACAAGAATCAGTTTCTTGACATCTGGCAACTGA
GGGAAAAAAGTCTTTCACCCCAGGATGAACAATGTGCTGTGGAGGAAGCACTGGATTGGAGAAGGGAGGAACTGTTACTTCTAAAGAAAG
AGAAAAGATGTGTTGATAGTCTCCTGAAGATGTGTGGGAACGTGAAACATCTGATACAAGTGGACTTTGGAGTGCTTGCAGTAAGACACT
CACAAGACCTCAGCAGTAAAAGATTAAATGACACCGTGACAGTGAGACTGTCCACCTCCTCGAACTCGCAGAGGGCAACGCATTACCACC
TGAGCTCCCAGGTCCAAGAAATGGCTGGGAAGATAGACTTGCTCAGAGACAGCCACATCTTCCAGCTCTTCTGGCGGGAAGCCGCAGAGC
CGCTGAGTGAGCCTAAGGAGGACCAGGAAGCCGCAGAGTTGCTGAGTGAGCCCGAAGAAGAATCAGAAAGGCACATCCTTGAGCTTGAAG
AGGTGTATGACTATTTGTATCAGCCTTCTTACAGAAAGTTCATTAAGTTGCACCAGGATCTAAAGTCAGGAGAGGTCACCCTTGCAGAGA
TTGATGTCATCTTCAAGGACTTTGTGAATAAATACACGGACCTGGATTCAGAACTTAAGATCATGTGCACCGTGGACCACCAGGACCAAA
GAGATTGGATCAAGGACCGAGTCGAACAGATCAAGGAATACCATCACCTGCACCAGGCTGTCCACGCAGCCAAGGTCATCTTGCAGGTCA
AAGAGAGCCTGGGACTGAACGGTGACTTCAGTGTTCTCAACACTTTACTAAATTTTACTGATAACTTCGACGACTTTCGCCGTGAAACAC
TGGACCAGATCAACCAGGAGCTCATCCAGGCCAAAAAGCTGCTCCAGGACATCAGCGAGGCCCGGTGCAAGGGGCTGCAGGCTCTGTCCC
TGAGAAAGGAGTTCATCTGCTGGGTCCGGGAGGCTCTTGGAGGCATCAATGAGCTGAAGGTGTTTGTGGACCTGGCCTCCATCTCAGCGG
GGGAGAATGACATTGATGTGGACCGGGTGGCCTGCTTCCATGACGCTGTGCAGGGCTACGCATCCCTGCTATTTAAGCTGGACCCCAGCG
TGGACTTCAGTGCATTCATGAAGCATCTGAAAAAGCTGTGGAAGGCTCTGGATAAGGACCAGTACCTGCCCAGGAAACTGTGTGACTCCG
CCAGGAACTTGGAATGGCTGAAGACTGTGAATGAGAGTCATGGGTCTGTGGAACGCTCATCCCTGACCCTGGCCACGGCCATCAACCAAA
GAGGCATCTATGTGATCCAGGCGCCCAAAGGTGGCCAAAAGATTTCCCCAGACACGGTTCTGCACTTGATCCTTCCTGAGAGCCCTGGCA
GCCACGAGGAGTCACGAGAGTACTCTTTAGAGGAGGTGAAGGAGCTTTTGAACAAGTTGATGCTGATGTCTGGCAAGAAGGATCGTAACA
ACACGGAAGTGGAGAGGTTTTCAGAGGTCTTCTGCAGTGTGCAGAGGCTCAGCCAGGCCTTCATCGACCTGCACTCTGCTGGGAATATGC
TGTTCAGGACGTGGATCGCCATGGCCTACTGCTCCCCCAAGCAGGGTGTGTCCCTCCAAATGGACTTTGGCTTGGACCTGGTGACGGAGC
TTAAAGAAGGTGGAGATGTCACTGAGCTGCTGGCAGCCCTCTGCAGGCAGATGGAGCACTTCCTTGACAGCTGGAAGAGATTTGTGACCC
AGAAGCGAATGGAGCACTTTTACCTGAACTTCTACACGGCAGAGCAGCTGGTTTACCTGAGCACTGAGCTCAGGAAGCAGCCCCCGAGTG
ATGCCGCCCTAACGATGCTATCCTTCATCAAAAGCAACTGCACCCTGAGGGATGTCTTAAGGGCCTCTGTGGGGTGTGGGAGTGAGGCCG
CCAGGTACCGCATGAGGAGAGTCATGGAAGAGCTCCCGCTGATGCTCTTATCAGAGTTCAGCCTGGTGGACAAGCTGAGGATCATCATGG
AGCAGTCCATGAGGTGCCTTCCTGCCTTCCTGCCCGACTGCCTCGACCTAGAGACCCTTGGCCACTGTCTGGCTCACCTGGCAGGGATGG
GTGGGTCTCCCGTGGAGCGTTGTCTCCCGAGAGGTCTGCAGGTCGGCCAGCCCAACCTCGTCGTCTGTGGCCACTCCGAGGTGTTGCCAG
CCGCCCTGGCTGTCTACATGCAAACCCCAAGCCAGCCCCTGCCCACTTACGATGAGGTGCTGCTCTGCACCCCGGCAACCACCTTTGAGG
AGGTGGCACTGTTGCTGCGCCGCTGCCTGACCCTGGGCTCCCTGGGGCACAAGGTCTACAGCCTGCTGTTCGCAGATCAGCTGAGCTACG
AGGTGGCACGCCAAGCGGAGGAGCTTTTCCACAATCTGTGCACGCAGCAGCACCGAGAAGACTACCAGCTCGTCATGGTCTGTGATGGGG
ACTGGGAGCACTGCTACCTCCCCTCTGCCTTCAGCCAGCACAAGGTCTTCGTCACCCCCCAGGCACCCCTCGAGGCCATCCAAGCCTACC
TGGCAGGTCACTACCGGGTCCCGAAGCAGACCCTGTCGGCGGCAGCCGTGTTCAATGACCGGCTGTGTGTTGGGATCGTGGCCTCGGAGC
GAGCAGGTGTTGGAAAGTCTCTGTACGTGAAGAGGTTGCACGACAAAATGAAGATGCAGTTAAACGTGAAAAATGTGCCTCTGAAAACAA
TTCGACTGATCGACCCTCAGGTGGATGAGAGCCGAGTCCTGGGCGCCCTGCTGCCCTTCCTGGATGCGCAGTATCAGAAGGTCCCCGTGC
TCTTTCACCTGGACGTGACCTCCTCAGTGCAGACTGGAATTTGGGTGTTTCTTTTCAAGCTCCTCATTTTACAATACTTAATGGATATAA
ATGGGAAAATGTGGCTTCGGAACCCCTGCCATTTGTATATCGTTGAAATCCTGGAAAGGAGGACGTCAGTGCCGTCGAGGAGCTCTTCAG
CGCTGCGTACACGTGTACCCCAGTTCAGTTTTCTTGACATCTTCCCAAAAGTCACCTGCAGGCCTCCCAAAGAGGTGATAGACATGGAGC
TGAGTGCCCTGAGGAGTGACACAGAGCCTGGGATGGATCTGTGGGAGTTCTGCAGCGAAACTTTCCAAAGACCTTACCAGTATTTAAGAC
GATTCAATCAAAACCAAGACCTAGACACGTTTCAGTATCAAGAAGGCTCTGTCGAAGGCACCCCGGAGGAATGCCTCCAGCATTTCCTGT
TTCACTGCGGGGTAATAAACCCATCCTGGTCAGAGCTTCGGAACTTTGCTCGGTTCCTGAATTATCAGCTCAGAGATTGTGAGGCCTCTC
TCTTCTGCAATCCGAGTTTTATTGGCGACACACTGAGGGGCTTCAAGAAGTTCGTGGTGACCTTCATGATCTTTATGGCAAGAGATTTTG
CCACACCATCACTCCACACCTCTGACCAAAGCCCGGGGAAGCACATGGTCACCATGGATGGGGTTAGGGAAGAAGATCTAGCGCCCTTCT
CCCTCCGGAAGAGGTGGGAGTCGGAGCCTCACCCATACGTTTTCTTCAATGACGACCACACAACCATGACATTCATCGGCTTCCATCTGC
AGCCCAACATCAACGGCAGTGTCGATGCCATCAGTCACTTGACTGGGAAGGTCATCAAGAGAGACGTCATGACCAGGGACCTGTACCAGG
GCCTGCTGCTCCAGAGGGTGCCCTTCAATGTCGACTTTGATAAACTGCCCAGACACAAGAAACTTGAGAGGCTCTGCCTGACCTTAGGGA
TCCCCCAGGCCACCGACCCCGACAAAACGTATGAGCTCACAACCGACAATATGCTTAAAATCCTTGCCATCGAGATGCGGTTCCGGTGTG
GGATCCCGGTTATCATCATGGGAGAAACTGGCTGTGGGAAAACCAGGCTTATTAAATTCCTTAGCGACCTGCGGCGTGGTGGTACCAATG
CTGACACCATAAAGCTGGTCAAGGTGCACGGAGGAACAACTGCAGACATGATCTACTCCAGAGTCAGGGAGGCTGAAAATGTGGCCTTCG
CCAATAAGGACCAACATCAGTTGGACACCATCTTGTTTTTTGATGAAGCCAACACAACGGAAGCTATAAGCTGTATCAAAGAAGTCCTGT
GTGATCATATGGTGGATGGCCAGCCTCTGGCTGAGGACTCTGGCCTGCATATTATAGCTGCCTGCAATCCATACCGGAAGCACTCTGAGG
AGATGATCTGCCGTTTGGAGTCAGCTGGTTTGGGCTACAGGGTTAGTATGGAGGAGACGGCCGACAGGCTGGGCTCCATTCCTCTGAGGC
AGCTGGTATACCGGGTCCATGCTCTGCCCCCGAGCCTGATTCCTCTGGTGTGGGACTTTGGACAACTGAGTGACGTTGCTGAAAAGCTCT
ACATCCAGCAGATTGTCCAGAGACTGGTTGAGTCCATCAGCCTAGATGAAAACGGGACTCGCGTGATCACAGAAGTCCTCTGCGCCTCTC
AGGGTTTCATGAGGAAAACAGAAGATGAGTGCAGCTTTGTCAGCCTCAGGGACGTGGAGCGCTGTGTGAAAGTTTTCAGGTGGTTCCACG
AGCACAGCGCGATGCTCTTAGCGCAGCTGAATGCCTTTCTCTCCAAGTCCAGCGTCAGCAAAAATCACACCGAGAGAGATCCCGTCCTCT
GGTCGTTGATGCTGGCCATCGGGGTGTGTTACCATGCCTCTTTAGAAAAGAAAGACTCATATCGGAAAGCCATCGCCAGGTTCTTTCCGA
AACCGTATGACGACAGCAGGCTGCTTCTGGATGAAATAACACGGGCACAGGATCTTTTTCTGGACGGCGTACCTCTGAGGAAAACCATCG
CCAAGAACTTGGCCTTGAAGGAGAACGTCTTCATGATGGTCGTCTGCATCGAGCTGAAGATTCCCCTCTTCCTGGTGGGGAAGCCCGGCA
GCTCCAAGTCTCTCGCCAAGACCATCGTGGCAGACGCCATGCAGGGCCCGGCTGCCTACTCAGATCTCTTCCGCAGCCTGAAGCAGGTCC
ACCTGGTGTCCTTCCAGTGCAGCCCGCACTCCACCCCACAGGGCATCATCAGCACCTTCCGGCAGTGCGCCCGCTTTCAGCAGGGGAAGG
ACCTGCAGCAGTACGTCTCTGTGGTGGTGTTAGATGAGGTGGGGCTGGCGGAAGACTCACCCAAAATGCCCCTGAAGACTCTGCACCCGC
TGCTGGAAGACGGATGCATTGAAGACGATCCCGCCCCCCACAAAAAGGTCGGCTTCGTGGGCATCTCCAACTGGGCCCTTGACCCTGCCA
AGATGAACCGGGGCATTTTTGTGTCACGTGGCAGCCCCAACGAGACAGAGCTCATAGAGAGCGCCAAGGGCATCTGCTCCTCAGACATCC
TCGTCCAGGACCGAGTCCAAGGGTACTTTGCGTCCTTTGCCAAAGCCTACGAAACGGTGTGTAAGCGCCAGGACAAGGAATTCTTCGGGC
TTCGTGACTACTACAGCCTCATCAAAATGGTCTTTGCTGCAGCAAAGGCTTCAAATAGAAAGCCTTCCCCGCAAGACATTGCACAGGCTG
TCCTTAGGAACTTCAGTGGCAAGGATGACATCCAAGCTTTGGACATCTTTCTGGCCAATTTGCCCGAGGCCAAGTGCTCAGAGGAAGTCA
GCCCCATGCAGCTGATCAAACAGAACATCTTTGGGCCTTCTCAGAAGGTGCCGGGTGGAGAGCAGGAAGATGCTGAGTCCCGCTACTTAC
TCGTGCTGACCAAAAACTACGTGGCACTGCAGATCCTGCAGCAGACATTCTTCGAGGGGGACCAGCAGCCGGAGATTATTTTTGGTTCTG
GTTTCCCCAAGGACCAAGAGTACACCCAGCTCTGCAGAAACATCAATCGTGTGAAGATCTGCATGGAAACAGGCAAGATGGTGTTGCTTC
TCAACCTGCAGAACCTCTACGAGAGCCTCTACGACGCACTCAACCAGTACTACGTCCACCTCGGCGGCCAGAAGTACGTGGACCTCGGTC
TGGGGACCCACCGCGTCAAATGTCGGGTTCACCCCAACTTCCGCCTGATTGTCATTGAAGAGAAAGACGTCGTGTACAAACACTTTCCCA
TCCCCCTCATTAACCGGCTGGAGAAGCACTATCTGGATATCAACACGGTGCTGGAGAAATGGCAGAAGAGCATCGTGGAGGAGCTCTGTG
CGTGGGTGGAGAAGTTCATCAATGTCAAAGCACATCATTTCCAGAAGAGGCACAAATACAGCCCCTCTGACGTCTTCATCGGCTACCACT
CGGACGCCTGCGCGTCTGTGGTGCTGCAGGTCATAGAGAGGCAGGGTCCCCGGGCCTTGACGGAGGAACTTCACCAGAAGGTGTCTGAGG
AGGCCAAATCGATCCTGCTGAACTGCGCTACGCCCGATGCCGTGGTCCGGCTGAGCGCCTACTCGCTGGGCGGGTTCGCAGCGGAGTGGC
TGTCGCAGGAGTACTTTCACAGACAGAGGCACAACTCCTTTGCAGATTTCCTTCAGGCACACCTGCACACGGCAGACCTGGAGCGCCACG
CCATCTTCACAGAGATCACCACTTTCTCCAGGCTGCTAACAAGTCACGACTGTGAAATTTTAGAATCAGAGGTCACAGGCAGGGCTCCGA
AACCCACACTCCTGTGGCTGCAGCAGTTTGACACCGAGTACTCATTCCTCAAAGAAGTCCGAAACTGTTTAACGAATACAGCCAAATGTA
AAATCCTCATTTTTCAGACAGATTTTGAAGATGGAATCCGTAGCGCCCAGCTCATTGCCTCAGCTAAGTATTCTGTTATAAATGAAATCA
ACAAAATACGAGAAAATGAGGACCGTATCTTCGTCTATTTCATCACAAAACTGTCCCGGGTGGGAAGAGGAACAGCCTATGTGGGCTTCC
ACGGAGGGCTGTGGCAGTCTGTCCACATCGATGACCTCCGGAGATCCACCCTCATGGTTTCTGATGTGACCAGGCTGCAGCATGTCACCA
TCAGCCAGCTGTTCGCGCCCGGAGACTTGCCTGAGCTGGGCTTGGAACACCGGGCGGAAGACGGCCATGAGGAGGCGATGGAGACGGAGG
CCAGCACATCAGGGGAGGTGGCAGAGGTGGCAGAGGAGGCCATGGAAACAGAAAGTTCTGAGAAGGTGGGAAAGGAAACCTCTGAACTCG
GAGGCAGTGATGTGTCGATCCTGGACACCACCAGGCTGCTGAGAAGCTGTGTGCAGAGCGCCGTGGGCATGCTCAGAGACCAGAACGAGA
GCTGCACGCGCAATATGCGGAGGGTGGTGCTCCTCCTGGGCCTCTTGAATGAGGATGACGCGTGCCACGCCTCTTTCTTGCGGGTATCCA
AGATGCGCCTCAGTGTCTTTTTAAAGAAGCAAGAAGAGAGCCAGTTTCACCCTCTGGAGTGGTTGGCAAGGGAAGCCTGCAACCAGGACG
CTCTCCAGGAGGCGGGCACATTCAGGCACACCCTCTGGAAGCGGGTCCAAGGTGCTGTCACCCCTCTGCTGGCGAGCATGATATCATTCA
TCGACAGAGACGGCAACCTAGAGTTACTGACCAGGCCAGATACTCCGCCCTGGGCAAGAGATCTTTGGATGTTTATTTTCAGTGACACGA
TGCTTCTGAACATTCCTCTTGTGATGAATAATGAAAGACATAAAGGTGAGATGGCCTACATCGTGGTGCAGAACCACATGAACCTTTCCG
AGAACGCTTCCAACAACGTCCCTTTCAGCTGGAAAATCAAGGACTATCTGGAGGAGCTGTGGGTCCAGGCTCAGTACATCACAGACGCAG
AAGGACTGCCCAAGAAGTTCGTGGACATCTTTCAGCAGACTCCTCTGGGCAGGTTTCTTGCCCAGCTCCATGGAGAGCCGCAGCAGGAAC
TTCTTCAGTGTTACTTGAAGGATTTCATTCTCTTGACCATGCGTGTGTCAACGGAGGAGGAATTAAAGTTTCTGCAGATGGCTCTGTGGT
CCTGCACTAGGAAACTGAAAGCGGCGTCAGAAGCGCCCGAGGAAGAGGTTTCCTTACCGTGGGTGCACCTTGCCTACCAGCGTTTCAGAA
GCCGTCTGCAGAACTTTTCCAGAATCCTGACCATCTACCCTCAGGTTCTCCACAGCCTGATGGAAGCCCGTTGGAACCATGAGCTGGCTG
GATGTGAGATGACCCTGGACGCATTTGCCGCAATGGCCTGCACGGAGATGCTGACAAGAAACACCCTGAAGCCCAGTCCCCAGGCGTGGC
TACAGTTGGTGAAGAATCTTTCCATGCCGCTGGAGCTCATCTGCTCCGATGAGCACATGCAAGGCAGCGGGAGCCTGGCCCAGGCTGTCA
TCAGGGAAGTCAGAGCCCAGTGGAGTCGGATTTTCTCCACCGCACTCTTCGTGGAGCACGTGCTCCTAGGAACCGAGAGCCGCGTCCCCG
AGTTACAGGGGCTGGTGACCGAGCACGTCTTCTTACTAGACAAGTGTCTTCGAGAGAACTCTGACGTGAAGACGCACGGGCCTTTTGAGG
CCGTGATGCGCACTCTCTGTGAATGCAAGGAGACAGCCAGCAAGACCCTCAGCAGGTTTGGGATTCAGCCGTGCTCCATCTGCCTGGGAG
ATGCAAAGGACCCCGTCTGTCTGCCCTGCGACCACGTGCACTGCCTGCGCTGCCTCAGGGCCTGGTTTGCCTCAGAGCAGATGATATGCC
CCTACTGTTTAACTGCCTTGCCAGACGAATTCTCTCCAGCTGTTTCCCAAGCGCACAGGGAAGCCATTGAAAAGCATGCCCGCTTCCGGC
AGATGTGCAACAGTTTCTTCGTAGACCTGGTGTCCACCATTTGCTTCAAGGACAACGCTCCGCCTGAGAAGGAAGTGATTGAGAGCCTGC
TCTCTCTCCTCTTCGTCCAAAAGGGGCGCTTAAGAGATGCTGCCCAGAGACACTGTGAACACACAAAATCTCTCTCTCCATTCAATGATG
TTGTGGATAAGACTCCTGTCATCCGCTCAGTGATACTGAAACTGCTTTTGAAGTACAGCTTTCATGATGTAAAAGATTATATTCAGGAAT
ATTTGACCCTGTTAAAAAAGAAAGCATTCATAACTGAAGATAAAACTGAACTGTACATGCTCTTCATCAACTGCCTGGAGGATTCAATAC
TTGAGAAGACCAGTGCTTACTCCAGAAATGATGAACTGAACCACCTAGAAGAGGAAGGTCGTTTCCTTAAGGCATATTCTCCAGCAAGCC
GGGGCCGAGAGCCTGCCAACGAGGCCTCGGTTGAATACCTGCAAGAGGTGGCCCGGATCCGCCTCTGCCTCGACAGAGCTGCAGATTTCC
TCTCGGAGCCTGAGGGAGGCCCAGAGATGGCCAAGGAGAAGCAGTGCTACCTGCAGCAAGTCAAGCAGTTCTGTATCCGGGTGGAGAACG
ACTGGCACCGGGTGTACCTGGTGCGGAAGCTCAGCAGCCAGCGGGGGATGGAGTTCGTGCAGGGCCTCTCCAAGCCCGGCCGCCCGCACC
AGTGGGTGTTTCCCAAGGACGTTGTCAAGCAGCAGGGGCTGCGGCAGGACCACCCAGGCCAGATGGATAGGTACCTGGTGTACGGCGATG
AATACAAGGCTCTCCGTGATGCTGTGGCCAAAGCTGTCCTCGAGTGCAAGCCACTGGGCATTAAGACTGCTCTGAAGGCCTGCAAGACCC
CCCAAAGCCAGCAGTCAGCCTACTTCCTGTTAACACTGTTTAGAGAGGTGGCTATTTTGTACAGATCCCACAATGCAAGCCTCCACCCCA
CGCCAGAGCAATGTGAAGCTGTGAGCAAATTCATTGGCGAATGCAAGATCCTTTCACCTCCTGATATCAGCCGTTTTGCAACATCGCTCG
TGGACAATTCTGTGCCATTGTTGAGGGCGGGGCCTAGTGACAGCAACCTTGATGGAACGGTGACAGAAATGGCCATTCATGCTGCAGCCG
TCCTTCTGTGTGGACAGAATGAACTCTTGGAGCCCCTAAAGAATCTGGCCTTCTCCCCAGCCACCATGGCGCATGCTTTTCTTCCAACCA
TGCCTGAAGACTTGCTGGCTCAAGCTCGGAGGTGGAAGGGTCTGGAGCGAGTCCACTGGTACACTTGTCCCAACGGCCATCCTTGCTCCG
TGGGAGAGTGTGGCAGGCCGATGGAACAGAGCATCTGCATTGACTGCCATGCGCCGATTGGAGGCATTGACCACAAACCTCGGGACGGCT
TTCATCTGGTCAAAGACAAGGCAGACAGAACGCAGACCGGCCACGTGCTGGGCAACCCGCAGCGGAGAGACGTGGTGACATGTGACCGAG
GGCTGCCCCCAGTGGTCTTCCTCCTTATCCGGCTACTCACTCACTTGGCTCTGCTTCTGGGAGCGTCCCAGAGTTCCCAGATCAGTCGCA
TCGAATACATTCATTCAAAGAACTTCATCCACCGGGATGTGAAGCCAGACAACTTCCTCATGGGCCTGGGGAAGAAGGGCAACCTGGTGT
ACATCATCGACTTCGGGCTGGCCAAGAAGTACCGGGATGCACGCACCCACCAGCACATCCCCTATCGTGAGAACAAGAACCTCACGGGGA
CGGCGCGGTACGCCTCCATCAACACGCACCTTGGAATTGAACAATCCCGAAGAGATGACTTGGAGTCTCTGGGCTACGTGCTAATGTACT
TCAACCTGGGCTCTCTCCCCTGGCAGGGGCTGAAGGCTGCCACCAAGAGACAGAAATACGAAAGGATTAGCGAGAAGAAAATGTCCACCC
CCATCGAAGTGTTGTGTAAAGGCTACCCTTCCGAATTTGCCACATACCTGAATTTCTGCCGTTCCTTGCGTTTTGACGACAAGCCTGACT
ACTCGTACCTGCGGCAGCTTTTCCGGAATCTGTTCCATCGCCAGGGCTTCTCCTATGACTACGTGTTCGACTGGAACATGCTCAAATTTG
GTGCCAGCCGGGCCGCCGATGACGCCGAGCGGGAGCGCAGGGACCGAGAGGAGCGGCTGAGACACTCGCGGAACCCGGCTACCCGCGGCC
TCCCTTCCACAGCCTCCGGCCGCCTGCGGGGGACGCAGGAAGTGGCTCCCCCCACACCCCTCACCCCTACCTCACACACGGCTAACACCT
CCCCCCGGCCCGTCTCCGGCATGGAGAGAGAGCGGAAAGTGAGTATGCGGCTGCACCGCGGGGCCCCCGTCAACATCTCCTCGTCCGACC
TCACAGGCCGACAAGATACCTCTCGCATGTCCACCTCACAGAGGAGCAGGGACATGGCATCTCTCCGGCTGCACGCGGCCCGCCAGGGCA
CCCGCTGCCGTCCCCAGCGCCCACGACGCACCTACTGAGGGCCCCGGCGGCCTCTGACCGGGCTCCCAGCCACGCAGGCCACTGCTGGCC
ACGAGGGCAGGTGGGTGTTAGGTGTCCAGGACAAGCCCAAGCGCTGGGCCGGGCTGGATGGAGGACAGGGTGCAAAGACCAGCCCTGGGC
ACTGACCACACCACGCACACTGCCAGCCAGGCAGAGGGGCGAAAAAGGGAAGGCAGGAGGGTCCTGTTTCTTAAACACAGCAGTGAATAA

>74967_74967_9_RNF213-CSNK1D_RNF213_chr17_78354787_ENST00000582970_CSNK1D_chr17_80211120_ENST00000398519_length(amino acids)=4914AA_BP=4597
MECPSCQHVSKEETPKFCSQCGERLPPAAPIADSENNNSTMASASEGEMECGQELKEEGGPCLFPGSDSWQENPEEPCSKASWTVQESKK
KKRKKKKKGNKSASSELASLPLSPASPCHLTLLSNPWPQDTALPHSQAQQSGPTGQPSQPPGTATTPLEGDGLSAPTEVGDSPLQAQALG
EAGVATGSEAQSSPQFQDHTEGEDQDASIPSGGRGLSQEGTGPPTSAGEGHSRTEDAAQELLLPESKGGSSEPGTELQTTEQQAGASASM
AVDAVAEPANAVKGAGKEMKEKTQRMKQPPATTPPFKTHCQEAETKTKDEMAAAEEKVGKNEQGEPEDLKKPEGKNRSAAAVKNEKEQKN
QEADVQEVKASTLSPGGGVTVFFHAIISLHFPFNPDLHKVFIRGGEEFGESKWDSNICELHYTRDLGHDRVLVEGIVCISKKHLDKYIPY
KYVIYNGESFEYEFIYKHQQKKGEYVNRCLFIKSSLLGSGDWHQYYDIVYMKPHGRLQKVMNHITDGPRKDLVKGKQIAAALMLDSTFSI
LQTWDTINLNSFFTQFEQFCFVLQQPMIYEGQAQLWTDLQYREKEVKRYLWQHLKKHVVPLPDGKSTDFLPVDCPVRSKLKTGLIVLFVV
EKIELLLEGSLDWLCHLLTSDASSPDEFHRDLSHILGIPQSWRLYLVNLCQRCMDTRTYTWLGALPVLHCCMELAPRHKDAWRQPEDTWA
ALEGLSFSPFREQMLDTSSLLQFMREKQHLLSIDEPLFRSWFSLLPLSHLVMYMENFIEHLGRFPAHILDCLSGIYYRLPGLEQVLNTQD
VQDVQNVQNILEMLLRLLDTYRDKIPEEALSPSYLTVCLKLHEAICSSTKLLKFYELPALSAEIVCRMIRLLSLVDSAGQRDETGNNSVQ
TVFQGTLAATKRWLREVFTKNMLTSSGASFTYVKEIEVWRRLVEIQFPAEHGWKESLLGDMEWRLTKEEPLSQITAYCNSCWDTKGLEDS
VAKTFEKCIIEAVSSACQSQTSILQGFSYSDLRKFGIVLSAVITKSWPRTADNFNDILKHLLTLADVKHVFRLCGTDEKILANVTEDAKR
LIAVADSVLTKVVGDLLSGTILVGQLELIIKHKNQFLDIWQLREKSLSPQDEQCAVEEALDWRREELLLLKKEKRCVDSLLKMCGNVKHL
IQVDFGVLAVRHSQDLSSKRLNDTVTVRLSTSSNSQRATHYHLSSQVQEMAGKIDLLRDSHIFQLFWREAAEPLSEPKEDQEAAELLSEP
EEESERHILELEEVYDYLYQPSYRKFIKLHQDLKSGEVTLAEIDVIFKDFVNKYTDLDSELKIMCTVDHQDQRDWIKDRVEQIKEYHHLH
QAVHAAKVILQVKESLGLNGDFSVLNTLLNFTDNFDDFRRETLDQINQELIQAKKLLQDISEARCKGLQALSLRKEFICWVREALGGINE
LKVFVDLASISAGENDIDVDRVACFHDAVQGYASLLFKLDPSVDFSAFMKHLKKLWKALDKDQYLPRKLCDSARNLEWLKTVNESHGSVE
RSSLTLATAINQRGIYVIQAPKGGQKISPDTVLHLILPESPGSHEESREYSLEEVKELLNKLMLMSGKKDRNNTEVERFSEVFCSVQRLS
QAFIDLHSAGNMLFRTWIAMAYCSPKQGVSLQMDFGLDLVTELKEGGDVTELLAALCRQMEHFLDSWKRFVTQKRMEHFYLNFYTAEQLV
YLSTELRKQPPSDAALTMLSFIKSNCTLRDVLRASVGCGSEAARYRMRRVMEELPLMLLSEFSLVDKLRIIMEQSMRCLPAFLPDCLDLE
TLGHCLAHLAGMGGSPVERCLPRGLQVGQPNLVVCGHSEVLPAALAVYMQTPSQPLPTYDEVLLCTPATTFEEVALLLRRCLTLGSLGHK
VYSLLFADQLSYEVARQAEELFHNLCTQQHREDYQLVMVCDGDWEHCYLPSAFSQHKVFVTPQAPLEAIQAYLAGHYRVPKQTLSAAAVF
NDRLCVGIVASERAGVGKSLYVKRLHDKMKMQLNVKNVPLKTIRLIDPQVDESRVLGALLPFLDAQYQKVPVLFHLDVTSSVQTGIWVFL
FKLLILQYLMDINGKMWLRNPCHLYIVEILERRTSVPSRSSSALRTRVPQFSFLDIFPKVTCRPPKEVIDMELSALRSDTEPGMDLWEFC
SETFQRPYQYLRRFNQNQDLDTFQYQEGSVEGTPEECLQHFLFHCGVINPSWSELRNFARFLNYQLRDCEASLFCNPSFIGDTLRGFKKF
VVTFMIFMARDFATPSLHTSDQSPGKHMVTMDGVREEDLAPFSLRKRWESEPHPYVFFNDDHTTMTFIGFHLQPNINGSVDAISHLTGKV
IKRDVMTRDLYQGLLLQRVPFNVDFDKLPRHKKLERLCLTLGIPQATDPDKTYELTTDNMLKILAIEMRFRCGIPVIIMGETGCGKTRLI
KFLSDLRRGGTNADTIKLVKVHGGTTADMIYSRVREAENVAFANKDQHQLDTILFFDEANTTEAISCIKEVLCDHMVDGQPLAEDSGLHI
IAACNPYRKHSEEMICRLESAGLGYRVSMEETADRLGSIPLRQLVYRVHALPPSLIPLVWDFGQLSDVAEKLYIQQIVQRLVESISLDEN
GTRVITEVLCASQGFMRKTEDECSFVSLRDVERCVKVFRWFHEHSAMLLAQLNAFLSKSSVSKNHTERDPVLWSLMLAIGVCYHASLEKK
DSYRKAIARFFPKPYDDSRLLLDEITRAQDLFLDGVPLRKTIAKNLALKENVFMMVVCIELKIPLFLVGKPGSSKSLAKTIVADAMQGPA
AYSDLFRSLKQVHLVSFQCSPHSTPQGIISTFRQCARFQQGKDLQQYVSVVVLDEVGLAEDSPKMPLKTLHPLLEDGCIEDDPAPHKKVG
FVGISNWALDPAKMNRGIFVSRGSPNETELIESAKGICSSDILVQDRVQGYFASFAKAYETVCKRQDKEFFGLRDYYSLIKMVFAAAKAS
NRKPSPQDIAQAVLRNFSGKDDIQALDIFLANLPEAKCSEEVSPMQLIKQNIFGPSQKVPGGEQEDAESRYLLVLTKNYVALQILQQTFF
EGDQQPEIIFGSGFPKDQEYTQLCRNINRVKICMETGKMVLLLNLQNLYESLYDALNQYYVHLGGQKYVDLGLGTHRVKCRVHPNFRLIV
IEEKDVVYKHFPIPLINRLEKHYLDINTVLEKWQKSIVEELCAWVEKFINVKAHHFQKRHKYSPSDVFIGYHSDACASVVLQVIERQGPR
ALTEELHQKVSEEAKSILLNCATPDAVVRLSAYSLGGFAAEWLSQEYFHRQRHNSFADFLQAHLHTADLERHAIFTEITTFSRLLTSHDC
EILESEVTGRAPKPTLLWLQQFDTEYSFLKEVRNCLTNTAKCKILIFQTDFEDGIRSAQLIASAKYSVINEINKIRENEDRIFVYFITKL
SRVGRGTAYVGFHGGLWQSVHIDDLRRSTLMVSDVTRLQHVTISQLFAPGDLPELGLEHRAEDGHEEAMETEASTSGEVAEVAEEAMETE
SSEKVGKETSELGGSDVSILDTTRLLRSCVQSAVGMLRDQNESCTRNMRRVVLLLGLLNEDDACHASFLRVSKMRLSVFLKKQEESQFHP
LEWLAREACNQDALQEAGTFRHTLWKRVQGAVTPLLASMISFIDRDGNLELLTRPDTPPWARDLWMFIFSDTMLLNIPLVMNNERHKGEM
AYIVVQNHMNLSENASNNVPFSWKIKDYLEELWVQAQYITDAEGLPKKFVDIFQQTPLGRFLAQLHGEPQQELLQCYLKDFILLTMRVST
EEELKFLQMALWSCTRKLKAASEAPEEEVSLPWVHLAYQRFRSRLQNFSRILTIYPQVLHSLMEARWNHELAGCEMTLDAFAAMACTEML
TRNTLKPSPQAWLQLVKNLSMPLELICSDEHMQGSGSLAQAVIREVRAQWSRIFSTALFVEHVLLGTESRVPELQGLVTEHVFLLDKCLR
ENSDVKTHGPFEAVMRTLCECKETASKTLSRFGIQPCSICLGDAKDPVCLPCDHVHCLRCLRAWFASEQMICPYCLTALPDEFSPAVSQA
HREAIEKHARFRQMCNSFFVDLVSTICFKDNAPPEKEVIESLLSLLFVQKGRLRDAAQRHCEHTKSLSPFNDVVDKTPVIRSVILKLLLK
YSFHDVKDYIQEYLTLLKKKAFITEDKTELYMLFINCLEDSILEKTSAYSRNDELNHLEEEGRFLKAYSPASRGREPANEASVEYLQEVA
RIRLCLDRAADFLSEPEGGPEMAKEKQCYLQQVKQFCIRVENDWHRVYLVRKLSSQRGMEFVQGLSKPGRPHQWVFPKDVVKQQGLRQDH
PGQMDRYLVYGDEYKALRDAVAKAVLECKPLGIKTALKACKTPQSQQSAYFLLTLFREVAILYRSHNASLHPTPEQCEAVSKFIGECKIL
SPPDISRFATSLVDNSVPLLRAGPSDSNLDGTVTEMAIHAAAVLLCGQNELLEPLKNLAFSPATMAHAFLPTMPEDLLAQARRWKGLERV
HWYTCPNGHPCSVGECGRPMEQSICIDCHAPIGGIDHKPRDGFHLVKDKADRTQTGHVLGNPQRRDVVTCDRGLPPVVFLLIRLLTHLAL
LLGASQSSQISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRR
DDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFS
YDYVFDWNMLKFGASRAADDAERERRDREERLRHSRNPATRGLPSTASGRLRGTQEVAPPTPLTPTSHTANTSPRPVSGMERERKVSMRL

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Fusion Gene PPI Analysis for RNF213-CSNK1D


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for RNF213-CSNK1D


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for RNF213-CSNK1D


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneRNF213C1846689MOYAMOYA DISEASE 29CTD_human;UNIPROT
HgeneRNF213C0026654Moyamoya Disease3ORPHANET
HgeneRNF213C2931384Moyamoya disease 13ORPHANET
TgeneC3808874ADVANCED SLEEP PHASE SYNDROME, FAMILIAL, 23GENOMICS_ENGLAND;UNIPROT
TgeneC1858496Advanced Sleep-Phase Syndrome, Familial1CTD_human;ORPHANET