Fusion Gene Studies
in Kim Lab

FusionBase FusionGDB FusionGDB2 FusionPDB FusionNeoAntigen FusionAI FusionNW FGviewer Publication Contact
FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:BARD1-ITGAV (FusionGDB2 ID:HG580TG3685)

Fusion Gene Summary for BARD1-ITGAV

check button Fusion gene summary
Fusion gene informationFusion gene name: BARD1-ITGAV
Fusion gene ID: hg580tg3685
HgeneTgene
Gene symbol

BARD1

ITGAV

Gene ID

580

3685

Gene nameBRCA1 associated RING domain 1integrin subunit alpha V
Synonyms-CD51|MSK8|VNRA|VTNR
Cytomap('BARD1')('ITGAV')

2q35

2q32.1

Type of geneprotein-codingprotein-coding
DescriptionBRCA1-associated RING domain protein 1BRCA1-associated RING domain gene 1RING-type E3 ubiquitin transferase BARD1integrin alpha-Vantigen identified by monoclonal antibody L230integrin alphaVbeta3integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)vitronectin receptor subunit alpha
Modification date2020032220200313
UniProtAcc

Q99728

.
Ensembl transtripts involved in fusion geneENST00000260947, ENST00000449967, 
ENST00000432456, ENST00000471787, 
Fusion gene scores* DoF score3 X 4 X 3=369 X 8 X 6=432
# samples 49
** MAII scorelog2(4/36*10)=0.15200309344505
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(9/432*10)=-2.26303440583379
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: BARD1 [Title/Abstract] AND ITGAV [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointBARD1(215632205)-ITGAV(187466747), # samples:1
Anticipated loss of major functional domain due to fusion event.BARD1-ITGAV seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
BARD1-ITGAV seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
BARD1-ITGAV seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
BARD1-ITGAV seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
BARD1-ITGAV seems lost the major protein functional domain in Hgene partner, which is a CGC due to the frame-shifted ORF.
BARD1-ITGAV seems lost the major protein functional domain in Hgene partner, which is a epigenetic factor due to the frame-shifted ORF.
BARD1-ITGAV seems lost the major protein functional domain in Hgene partner, which is a tumor suppressor due to the frame-shifted ORF.
BARD1-ITGAV seems lost the major protein functional domain in Tgene partner, which is a CGC due to the frame-shifted ORF.
BARD1-ITGAV seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
BARD1-ITGAV seems lost the major protein functional domain in Tgene partner, which is a tumor suppressor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneBARD1

GO:0046826

negative regulation of protein export from nucleus

15265711

HgeneBARD1

GO:0085020

protein K6-linked ubiquitination

12890688|20351172

TgeneITGAV

GO:0007155

cell adhesion

10218736

TgeneITGAV

GO:0008284

positive regulation of cell proliferation

19578119

TgeneITGAV

GO:0033627

cell adhesion mediated by integrin

12807887|17158881

TgeneITGAV

GO:0034446

substrate adhesion-dependent cell spreading

24658351

TgeneITGAV

GO:0045785

positive regulation of cell adhesion

10708943

TgeneITGAV

GO:0050764

regulation of phagocytosis

10570297

TgeneITGAV

GO:0070588

calcium ion transmembrane transport

18395422

TgeneITGAV

GO:1901388

regulation of transforming growth factor beta activation

22278742

TgeneITGAV

GO:2000536

negative regulation of entry of bacterium into host cell

10570297


check buttonFusion gene breakpoints across BARD1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across ITGAV (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-BR-8589BARD1chr2

215632205

-ITGAVchr2

187466747

+


Top

Fusion Gene ORF analysis for BARD1-ITGAV

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000260947ENST00000474571BARD1chr2

215632205

-ITGAVchr2

187466747

+
5CDS-intronENST00000449967ENST00000474571BARD1chr2

215632205

-ITGAVchr2

187466747

+
Frame-shiftENST00000449967ENST00000261023BARD1chr2

215632205

-ITGAVchr2

187466747

+
Frame-shiftENST00000449967ENST00000374907BARD1chr2

215632205

-ITGAVchr2

187466747

+
Frame-shiftENST00000449967ENST00000433736BARD1chr2

215632205

-ITGAVchr2

187466747

+
In-frameENST00000260947ENST00000261023BARD1chr2

215632205

-ITGAVchr2

187466747

+
In-frameENST00000260947ENST00000374907BARD1chr2

215632205

-ITGAVchr2

187466747

+
In-frameENST00000260947ENST00000433736BARD1chr2

215632205

-ITGAVchr2

187466747

+
intron-3CDSENST00000432456ENST00000261023BARD1chr2

215632205

-ITGAVchr2

187466747

+
intron-3CDSENST00000432456ENST00000374907BARD1chr2

215632205

-ITGAVchr2

187466747

+
intron-3CDSENST00000432456ENST00000433736BARD1chr2

215632205

-ITGAVchr2

187466747

+
intron-3CDSENST00000471787ENST00000261023BARD1chr2

215632205

-ITGAVchr2

187466747

+
intron-3CDSENST00000471787ENST00000374907BARD1chr2

215632205

-ITGAVchr2

187466747

+
intron-3CDSENST00000471787ENST00000433736BARD1chr2

215632205

-ITGAVchr2

187466747

+
intron-intronENST00000432456ENST00000474571BARD1chr2

215632205

-ITGAVchr2

187466747

+
intron-intronENST00000471787ENST00000474571BARD1chr2

215632205

-ITGAVchr2

187466747

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000260947BARD1chr2215632205-ENST00000261023ITGAVchr2187466747+82741703346641553
ENST00000260947BARD1chr2215632205-ENST00000374907ITGAVchr2187466747+81621703345561517
ENST00000260947BARD1chr2215632205-ENST00000433736ITGAVchr2187466747+48141703346641553

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000260947ENST00000261023BARD1chr2215632205-ITGAVchr2187466747+4.86E-050.9999515
ENST00000260947ENST00000374907BARD1chr2215632205-ITGAVchr2187466747+5.54E-050.99994457
ENST00000260947ENST00000433736BARD1chr2215632205-ITGAVchr2187466747+0.0002783010.9997217

Top

Fusion Genomic Features for BARD1-ITGAV


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
BARD1chr2215632205-ITGAVchr2187466747+5.83E-070.9999994
BARD1chr2215632205-ITGAVchr2187466747+5.83E-070.9999994

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

Top

Fusion Protein Features for BARD1-ITGAV


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr2:215632205/chr2:187466747)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
BARD1

Q99728

.
FUNCTION: E3 ubiquitin-protein ligase. The BRCA1-BARD1 heterodimer specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain genomic stability. Plays a central role in the control of the cell cycle in response to DNA damage. Acts by mediating ubiquitin E3 ligase activity that is required for its tumor suppressor function. Also forms a heterodimer with CSTF1/CSTF-50 to modulate mRNA processing and RNAP II stability by inhibiting pre-mRNA 3' cleavage. {ECO:0000269|PubMed:12890688, ECO:0000269|PubMed:14976165, ECO:0000269|PubMed:20351172}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneBARD1chr2:215632205chr2:187466747ENST00000260947-611400_403522778.0Compositional biasNote=Poly-Ser
HgeneBARD1chr2:215632205chr2:187466747ENST00000260947-611427_459522778.0RepeatNote=ANK 1
HgeneBARD1chr2:215632205chr2:187466747ENST00000260947-611460_492522778.0RepeatNote=ANK 2
HgeneBARD1chr2:215632205chr2:187466747ENST00000260947-611493_525522778.0RepeatNote=ANK 3
HgeneBARD1chr2:215632205chr2:187466747ENST00000260947-61150_87522778.0Zinc fingerRING-type
TgeneITGAVchr2:215632205chr2:187466747ENST00000261023030260_268611049.0Calcium bindingOntology_term=ECO:0000255,ECO:0000269
TgeneITGAVchr2:215632205chr2:187466747ENST00000261023030314_322611049.0Calcium bindingOntology_term=ECO:0000255,ECO:0000269
TgeneITGAVchr2:215632205chr2:187466747ENST00000261023030379_387611049.0Calcium bindingOntology_term=ECO:0000255,ECO:0000269
TgeneITGAVchr2:215632205chr2:187466747ENST00000261023030443_451611049.0Calcium bindingOntology_term=ECO:0000255,ECO:0000269
TgeneITGAVchr2:215632205chr2:187466747ENST00000374907028260_268611013.0Calcium bindingOntology_term=ECO:0000255,ECO:0000269
TgeneITGAVchr2:215632205chr2:187466747ENST00000374907028314_322611013.0Calcium bindingOntology_term=ECO:0000255,ECO:0000269
TgeneITGAVchr2:215632205chr2:187466747ENST00000374907028379_387611013.0Calcium bindingOntology_term=ECO:0000255,ECO:0000269
TgeneITGAVchr2:215632205chr2:187466747ENST00000374907028443_451611013.0Calcium bindingOntology_term=ECO:0000255,ECO:0000269
TgeneITGAVchr2:215632205chr2:187466747ENST00000433736030260_268151003.0Calcium bindingOntology_term=ECO:0000255,ECO:0000269
TgeneITGAVchr2:215632205chr2:187466747ENST00000433736030314_322151003.0Calcium bindingOntology_term=ECO:0000255,ECO:0000269
TgeneITGAVchr2:215632205chr2:187466747ENST00000433736030379_387151003.0Calcium bindingOntology_term=ECO:0000255,ECO:0000269
TgeneITGAVchr2:215632205chr2:187466747ENST00000433736030443_451151003.0Calcium bindingOntology_term=ECO:0000255,ECO:0000269
TgeneITGAVchr2:215632205chr2:187466747ENST000002610230301019_1023611049.0MotifNote=GFFKR motif
TgeneITGAVchr2:215632205chr2:187466747ENST000003749070281019_1023611013.0MotifNote=GFFKR motif
TgeneITGAVchr2:215632205chr2:187466747ENST000004337360301019_1023151003.0MotifNote=GFFKR motif
TgeneITGAVchr2:215632205chr2:187466747ENST00000261023030109_170611049.0RepeatFG-GAP 2
TgeneITGAVchr2:215632205chr2:187466747ENST00000261023030173_225611049.0RepeatFG-GAP 3
TgeneITGAVchr2:215632205chr2:187466747ENST00000261023030237_291611049.0RepeatFG-GAP 4
TgeneITGAVchr2:215632205chr2:187466747ENST00000261023030292_357611049.0RepeatFG-GAP 5
TgeneITGAVchr2:215632205chr2:187466747ENST00000261023030358_415611049.0RepeatFG-GAP 6
TgeneITGAVchr2:215632205chr2:187466747ENST00000261023030419_482611049.0RepeatFG-GAP 7
TgeneITGAVchr2:215632205chr2:187466747ENST00000374907028109_170611013.0RepeatFG-GAP 2
TgeneITGAVchr2:215632205chr2:187466747ENST00000374907028173_225611013.0RepeatFG-GAP 3
TgeneITGAVchr2:215632205chr2:187466747ENST00000374907028237_291611013.0RepeatFG-GAP 4
TgeneITGAVchr2:215632205chr2:187466747ENST00000374907028292_357611013.0RepeatFG-GAP 5
TgeneITGAVchr2:215632205chr2:187466747ENST00000374907028358_415611013.0RepeatFG-GAP 6
TgeneITGAVchr2:215632205chr2:187466747ENST00000374907028419_482611013.0RepeatFG-GAP 7
TgeneITGAVchr2:215632205chr2:187466747ENST00000433736030109_170151003.0RepeatFG-GAP 2
TgeneITGAVchr2:215632205chr2:187466747ENST00000433736030173_225151003.0RepeatFG-GAP 3
TgeneITGAVchr2:215632205chr2:187466747ENST00000433736030237_291151003.0RepeatFG-GAP 4
TgeneITGAVchr2:215632205chr2:187466747ENST00000433736030292_357151003.0RepeatFG-GAP 5
TgeneITGAVchr2:215632205chr2:187466747ENST0000043373603032_98151003.0RepeatFG-GAP 1
TgeneITGAVchr2:215632205chr2:187466747ENST00000433736030358_415151003.0RepeatFG-GAP 6
TgeneITGAVchr2:215632205chr2:187466747ENST00000433736030419_482151003.0RepeatFG-GAP 7
TgeneITGAVchr2:215632205chr2:187466747ENST000002610230301017_1048611049.0Topological domainCytoplasmic
TgeneITGAVchr2:215632205chr2:187466747ENST000003749070281017_1048611013.0Topological domainCytoplasmic
TgeneITGAVchr2:215632205chr2:187466747ENST000004337360301017_1048151003.0Topological domainCytoplasmic
TgeneITGAVchr2:215632205chr2:187466747ENST0000043373603031_992151003.0Topological domainExtracellular
TgeneITGAVchr2:215632205chr2:187466747ENST00000261023030993_1016611049.0TransmembraneHelical
TgeneITGAVchr2:215632205chr2:187466747ENST00000374907028993_1016611013.0TransmembraneHelical
TgeneITGAVchr2:215632205chr2:187466747ENST00000433736030993_1016151003.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneBARD1chr2:215632205chr2:187466747ENST00000260947-611542_545522778.0Compositional biasNote=Poly-Leu
HgeneBARD1chr2:215632205chr2:187466747ENST00000260947-611560_653522778.0DomainBRCT 1
HgeneBARD1chr2:215632205chr2:187466747ENST00000260947-611667_777522778.0DomainBRCT 2
HgeneBARD1chr2:215632205chr2:187466747ENST00000260947-611554_558522778.0RegionNote=Flexible linker
HgeneBARD1chr2:215632205chr2:187466747ENST00000260947-611526_546522778.0RepeatNote=ANK 4%3B degenerate
TgeneITGAVchr2:215632205chr2:187466747ENST0000026102303032_98611049.0RepeatFG-GAP 1
TgeneITGAVchr2:215632205chr2:187466747ENST0000037490702832_98611013.0RepeatFG-GAP 1
TgeneITGAVchr2:215632205chr2:187466747ENST0000026102303031_992611049.0Topological domainExtracellular
TgeneITGAVchr2:215632205chr2:187466747ENST0000037490702831_992611013.0Topological domainExtracellular


Top

Fusion Gene Sequence for BARD1-ITGAV


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>8979_8979_1_BARD1-ITGAV_BARD1_chr2_215632205_ENST00000260947_ITGAV_chr2_187466747_ENST00000261023_length(transcript)=8274nt_BP=1703nt
CCTCTGGCGGCCCGCCGTCCCAGACGCGGGAAGAGCTTGGCCGGTTTCGAGTCGCTGGCCTGCAGCTTCCCTGTGGTTTCCCGAGGCTTC
CTTGCTTCCCGCTCTGCGAGGAGCCTTTCATCCGAAGGCGGGACGATGCCGGATAATCGGCAGCCGAGGAACCGGCAGCCGAGGATCCGC
TCCGGGAACGAGCCTCGTTCCGCGCCCGCCATGGAACCGGATGGTCGCGGTGCCTGGGCCCACAGTCGCGCCGCGCTCGACCGCCTGGAG
AAGCTGCTGCGCTGCTCGCGTTGTACTAACATTCTGAGAGAGCCTGTGTGTTTAGGAGGATGTGAGCACATCTTCTGTAGTAATTGTGTA
AGTGACTGCATTGGAACTGGATGTCCAGTGTGTTACACCCCGGCCTGGATACAAGACTTGAAGATAAATAGACAACTGGACAGCATGATT
CAACTTTGTAGTAAGCTTCGAAATTTGCTACATGACAATGAGCTGTCAGATTTGAAAGAAGATAAACCTAGGAAAAGTTTGTTTAATGAT
GCAGGAAACAAGAAGAATTCAATTAAAATGTGGTTTAGCCCTCGAAGTAAGAAAGTCAGATATGTTGTGAGTAAAGCTTCAGTGCAAACC
CAGCCTGCAATAAAAAAAGATGCAAGTGCTCAGCAAGACTCATATGAATTTGTTTCCCCAAGTCCTCCTGCAGATGTTTCTGAGAGGGCT
AAAAAGGCTTCTGCAAGATCTGGAAAAAAGCAAAAAAAGAAAACTTTAGCTGAAATCAACCAAAAATGGAATTTAGAGGCAGAAAAAGAA
GATGGTGAATTTGACTCCAAAGAGGAATCTAAGCAAAAGCTGGTATCCTTCTGTAGCCAACCATCTGTTATCTCCAGTCCTCAGATAAAT
GGTGAAATAGACTTACTAGCAAGTGGCTCCTTGACAGAATCTGAATGTTTTGGAAGTTTAACTGAAGTCTCTTTACCATTGGCTGAGCAA
ATAGAGTCTCCAGACACTAAGAGCAGGAATGAAGTAGTGACTCCTGAGAAGGTCTGCAAAAATTATCTTACATCTAAGAAATCTTTGCCA
TTAGAAAATAATGGAAAACGTGGCCATCACAATAGACTTTCCAGTCCCATTTCTAAGAGATGTAGAACCAGCATTCTGAGCACCAGTGGA
GATTTTGTTAAGCAAACGGTGCCCTCAGAAAATATACCATTGCCTGAATGTTCTTCACCACCTTCATGCAAACGTAAAGTTGGTGGTACA
TCAGGGAGGAAAAACAGTAACATGTCCGATGAATTCATTAGTCTTTCACCAGGTACACCACCTTCTACATTAAGTAGTTCAAGTTACAGG
CGAGTGATGTCTAGTCCCTCAGCAATGAAGCTGTTGCCCAATATGGCTGTGAAAAGAAATCATAGAGGAGAGACTTTGCTCCATATTGCT
TCTATTAAGGGCGACATACCTTCTGTTGAATACCTTTTACAAAATGGAAGTGATCCAAATGTTAAAGACCATGCTGGATGGACACCATTG
CATGAAGCTTGCAATCATGGGCACCTGAAGGTAGTGGAATTATTGCTCCAGCATAAGGCATTGGTGAACACCACCGGGTATCAAAATGAC
TCACCACTTCACGATGCAGCCAAGAATGGGCATGTGGATATAGTCAAGCTGTTACTTTCCTATGGAGCCTCCAGAAATGCTGTCCGGATG
TTTCTTCTCGTGGGAGCTCCCAAAGCAAACACCACCCAGCCTGGGATTGTGGAAGGAGGGCAGGTCCTCAAATGTGACTGGTCTTCTACC
CGCCGGTGCCAGCCAATTGAATTTGATGCAACAGGCAATAGAGATTATGCCAAGGATGATCCATTGGAATTTAAGTCCCATCAGTGGTTT
GGAGCATCTGTGAGGTCGAAACAGGATAAAATTTTGGCCTGTGCCCCATTGTACCATTGGAGAACTGAGATGAAACAGGAGCGAGAGCCT
GTTGGAACATGCTTTCTTCAAGATGGAACAAAGACTGTTGAGTATGCTCCATGTAGATCACAAGATATTGATGCTGATGGACAGGGATTT
TGTCAAGGAGGATTCAGCATTGATTTTACTAAAGCTGACAGAGTACTTCTTGGTGGTCCTGGTAGCTTTTATTGGCAAGGTCAGCTTATT
TCGGATCAAGTGGCAGAAATCGTATCTAAATACGACCCCAATGTTTACAGCATCAAGTATAATAACCAATTAGCAACTCGGACTGCACAA
GCTATTTTTGATGACAGCTATTTGGGTTATTCTGTGGCTGTCGGAGATTTCAATGGTGATGGCATAGATGACTTTGTTTCAGGAGTTCCA
AGAGCAGCAAGGACTTTGGGAATGGTTTATATTTATGATGGGAAGAACATGTCCTCCTTATACAATTTTACTGGCGAGCAGATGGCTGCA
TATTTCGGATTTTCTGTAGCTGCCACTGACATTAATGGAGATGATTATGCAGATGTGTTTATTGGAGCACCTCTCTTCATGGATCGTGGC
TCTGATGGCAAACTCCAAGAGGTGGGGCAGGTCTCAGTGTCTCTACAGAGAGCTTCAGGAGACTTCCAGACGACAAAGCTGAATGGATTT
GAGGTCTTTGCACGGTTTGGCAGTGCCATAGCTCCTTTGGGAGATCTGGACCAGGATGGTTTCAATGATATTGCAATTGCTGCTCCATAT
GGGGGTGAAGATAAAAAAGGAATTGTTTATATCTTCAATGGAAGATCAACAGGCTTGAACGCAGTCCCATCTCAAATCCTTGAAGGGCAG
TGGGCTGCTCGAAGCATGCCACCAAGCTTTGGCTATTCAATGAAAGGAGCCACAGATATAGACAAAAATGGATATCCAGACTTAATTGTA
GGAGCTTTTGGTGTAGATCGAGCTATCTTATACAGGGCCAGACCAGTTATCACTGTAAATGCTGGTCTTGAAGTGTACCCTAGCATTTTA
AATCAAGACAATAAAACCTGCTCACTGCCTGGAACAGCTCTCAAAGTTTCCTGTTTTAATGTTAGGTTCTGCTTAAAGGCAGATGGCAAA
GGAGTACTTCCCAGGAAACTTAATTTCCAGGTGGAACTTCTTTTGGATAAACTCAAGCAAAAGGGAGCAATTCGACGAGCACTGTTTCTC
TACAGCAGGTCCCCAAGTCACTCCAAGAACATGACTATTTCAAGGGGGGGACTGATGCAGTGTGAGGAATTGATAGCGTATCTGCGGGAT
GAATCTGAATTTAGAGACAAACTCACTCCAATTACTATTTTTATGGAATATCGGTTGGATTATAGAACAGCTGCTGATACAACAGGCTTG
CAACCCATTCTTAACCAGTTCACGCCTGCTAACATTAGTCGACAGGCTCACATTCTACTTGACTGTGGTGAAGACAATGTCTGTAAACCC
AAGCTGGAAGTTTCTGTAGATAGTGATCAAAAGAAGATCTATATTGGGGATGACAACCCTCTGACATTGATTGTTAAGGCTCAGAATCAA
GGAGAAGGTGCCTACGAAGCTGAGCTCATCGTTTCCATTCCACTGCAGGCTGATTTCATCGGGGTTGTCCGAAACAATGAAGCCTTAGCA
AGACTTTCCTGTGCATTTAAGACAGAAAACCAAACTCGCCAGGTGGTATGTGACCTTGGAAACCCAATGAAGGCTGGAACTCAACTCTTA
GCTGGTCTTCGTTTCAGTGTGCACCAGCAGTCAGAGATGGATACTTCTGTGAAATTTGACTTACAAATCCAAAGCTCAAATCTATTTGAC
AAAGTAAGCCCAGTTGTATCTCACAAAGTTGATCTTGCTGTTTTAGCTGCAGTTGAGATAAGAGGAGTCTCGAGTCCTGATCATGTCTTT
CTTCCGATTCCAAACTGGGAGCACAAGGAGAACCCTGAGACTGAAGAAGATGTTGGGCCAGTTGTTCAGCACATCTATGAGCTGAGAAAC
AATGGTCCAAGTTCATTCAGCAAGGCAATGCTCCATCTTCAGTGGCCTTACAAATATAATAATAACACTCTGTTGTATATCCTTCATTAT
GATATTGATGGACCAATGAACTGCACTTCAGATATGGAGATCAACCCTTTGAGAATTAAGATCTCATCTTTGCAAACAACTGAAAAGAAT
GACACGGTTGCCGGGCAAGGTGAGCGGGACCATCTCATCACTAAGCGGGATCTTGCCCTCAGTGAAGGAGATATTCACACTTTGGGTTGT
GGAGTTGCTCAGTGCTTGAAGATTGTCTGCCAAGTTGGGAGATTAGACAGAGGAAAGAGTGCAATCTTGTACGTAAAGTCATTACTGTGG
ACTGAGACTTTTATGAATAAAGAAAATCAGAATCATTCCTATTCTCTGAAGTCGTCTGCTTCATTTAATGTCATAGAGTTTCCTTATAAG
AATCTTCCAATTGAGGATATCACCAACTCCACATTGGTTACCACTAATGTCACCTGGGGCATTCAGCCAGCGCCCATGCCTGTGCCTGTG
TGGGTGATCATTTTAGCAGTTCTAGCAGGATTGTTGCTACTGGCTGTTTTGGTATTTGTAATGTACAGGATGGGCTTTTTTAAACGGGTC
CGGCCACCTCAAGAAGAACAAGAAAGGGAGCAGCTTCAACCTCATGAAAATGGTGAAGGAAACTCAGAAACTTAACTGCAGTTTTTAAGT
TATGCTACATCTTGACCCACTAGAATTAGCAACTTTATTATAGATTTAAACTTTCTTCATGAGGAGTAAAAATCCAAGGCTTTACTGCTG
ATAGTGCTAATTGGCATTAACCACAAAATGAGAATTATATTTGTCAACCTTCTCCTTATAAATAAGTTCAGACATACATTTAATAACATA
GGGTGACTTGTGTTTTTAGGTATTTAAATAATAAAATTTCAAGGGATAGTTTTTATTCAATGTATATAAGACAGGTAGTGCCTGATTTAC
TACTTTATATAAAATAGTACCTCCTTCAGTTACTGTTTCTGATTTAATGTACGGAACTTTATTTGTTGTTGTTGTTGTTGTTGTTGTTGT
TGTTTTAAAGCAGTCCAAATTTGGACCTTAGCAATCATGTCTTTTGTATAGGTACTTAATGTTAATACATATTACACTACAGTTTACTTT
TCAGAATACTAAAGACTTTATAACTGCATGAACTTGGATTTTTTTAATCACTCATATGGTAGAATTTTATAAACACATACATGATACCAT
CCAAATTCTTGCTTTTAATAACAAAGGTACAATATTTTGTTTTAGTATGAAAATCTGGTAGATCCTATTACACTTCTGTTTATATTAAAT
CCACAATATTTTATTACATTTTTAACTTGTATAAATTTTAGGTCAAATCCTTCAAGCCAACCTATACTAAAAATTAGTTCCATAATCACA
AATGGCTCTTTTGTGTAATTGTTTAATTTCACCTGAATATCATAATGCTTAAAGCCATATGGAGTTGGAAATTATTTCCAAAGCATATTT
ATTCCATTGTTTTAGTCTGGCTATTTACAGTATAAAAAAAGCATTTTTATTAAAATACTGTGTAGTTCTTTGAGATAGTTGCTTATGCAT
ATAGTAAGTATTACATTCTTAGAGTAGAGCAGAGTTTTTAGTTAGTATTAATTTATTTTCCTCCATTCATGTACTTTTCCTTATATTTCC
AAAACTGTTACTGAGAATGGGTCAAGATCAGTGAGAAATCTTTACAGTTGACAGGAACCTGGACCCCTTACCCCAACTTTATGAGTAATG
CTTGGAATAAAAACTCTTAAGGCAACTCACTGATTTACTTCTAGCAATAGCATGATGTTACAGGAATATTACCTCTGTTTAAGCAAGGTA
ATGTGTAAAATCAGTCTCGGCTGTCAGAATAACTTCTAAAAGGTATTTTTATAAGCAGTTCAAGTTACTGAAAACCTTTTAAACCTTTCT
GAAGTTCGTTAGTATAAATTACTTTTCTAGGATTATTAATAAAAGCCACATAGGTGGCAAGTTGTAGTTTTATATGGCTCTGTAGAGTGG
TGAACCTTCTAGAGGAATATATGATTTATTCACAGTTCCTCAAGGCCTGGGGATGATGATCAGTTATACCTATTTTTGTGCAATTACATC
ATGTTGTACATTAGAAATGGAGAGTTTAATAGCTCTTTAACTGCTGTCCTCATTAGGTAATGATAAATATTTCCCTTAAATAATTGACTA
TTTTGCTGTGTTTTAAAAATGATTGAAATTTATCTTGCCATATCTCATAATTTCATGCACAAGTTGACTGAGCTAATCTTGAGAATATAT
TCGTAAAATAGGAGCACATTTAGTTGAGGTATACAAGGTAGGACTCTAGACAAAACCTTCTATTTTAGCTTTAGTGAATTTCAAAAGTAA
TGGGTCTTGGAGTATAGATTTTTATTAGTAGCTTGAAAGAGCTTAATCATATGCAGTAAGTATTTTTATTACCAATAAATTTAAAATTTT
TTAAGAAAAATATTTTTATCCTAGGGCCAAGTGTTGCCTGCCACCAATCAGTAAGTTAGTCTATAACAAATTTTACCCTAACAGTTTTAC
CACCTAGTAACAGTCATTTCTGAAAATATGTTGGATAGAAAGTCACTCTTTGGCAAAAGTGTTAGAATTTGCTTTTGTGCCATCTATTCC
TTTTATGGCATCTATCTTGAAAGTAATCTTGTATTGGAGATTGAAAGATGCTGTAATTTAGAAATTAACATGATATCTTAAATTACCTTT
ATGAAATATAGTTTTGTATAATAGCATAGATTTTCCTTCAAAAAATGAACATTTATATATCTACAAAAATATGGAGAAGAGTAATTTGAA
AGCCTACTTTCTGAAGAAAATGGTGGGATTTTTTTTTATCATGATTAAATATCAAAAAATTGCCCTATGAAAACTTTAAATCTCTAAAAC
ATTTGAAATACTACCATATTTGTGATTTATTGAGAATAAAAATCCATTTTGAAATGTAAAATTTTTATGATCTGATTCAGTTTTAAGAAA
ACATGAATGAACTAGAAGATATTAAAAACATTTGACATTGGTAAGAAATATTGATACTGATATTGATTTTTATATAGGTATTTATTTCAG
AATTGATATTTTGAGAAAAATACATGTGAGTCATTTTTTCTGTTTCTCTTTTCTCTTAACGATTATCACTGTAATTCTGAATCTGAAAGG
TAAAACAATTAGTCAAAATATTATTGCCATCATTCTACCTGTGTTATGAAACTACTTATTCATAGTTAATTCTCATTAACACTTACATTT
CCATAAAGAAAACTCAAGTATTAATAAAAGAGACTTTACTGGCTTAAGAGGGCTGTGAAAGATTTTTGATAGTGAATCATGACCCTAAGG
GAGAGATTTGTGTGATAAAAGTATTGTATATAATAGATCAGCGATTTTTGTAAGGCAAACAGAATTTGTAAGTTGGCAGATCTTCCTAAG
TTGCAAAATGTAATGATGAGCTTGGTGGAGAAGAATGAGTCGTTCTTGGAATACCTATGTGCAGCCACTACCCATCTCAATGTCACCTTG
TTTGCATTCTTGGATAGCTTGTATATGTAGTAGTTTGATGAATAATTTAAAGAAAAACACCTAAAATTTGAAAAATGATTGTAGGATCAA
AAAAGGCAGATGAAATTACTTAATACTCAGTGTTTTGGAGAGTATTCCTTTTAGTTTGTTGGTTGGCTGGTTTGAACGATAGAAATATGC
AGCATGCAATATATGCTTATATTTCATTTTAATTTCTGATATATAATGAACTTCTTGGGAGAGGTACTGAATCTTTGATGTTTTTTGTCA
TTGTTCTCAAGTGCAATATAACAATGTAACCAAATCTAGATAATTTCAAAGTTGTCATTAATTTAGTAAGCCTAATATAAACAAATATTT
GTATTATTTTTGTTAGCAGGAAAGAGTGATTAAGTGAGGTTATTTACCCCTAAATGGTCCATTCTGCATTGTATTTCAGGCTGGAAATGA
ATTATTCTTTACCAGTTTTGAAACACTTTGAAATATCCTAAGGTAACTTGGAAGCTGTGTAGTATATCAAATTAATTTGCTACCTAATAA
CATAGAAAGTAAATATCTTTGTGGTCACCCACATTGGGTGAGACAGAAAATGAATCTGTTCTAAAATTTGTAATTTGCTAACTTGATTTG

>8979_8979_1_BARD1-ITGAV_BARD1_chr2_215632205_ENST00000260947_ITGAV_chr2_187466747_ENST00000261023_length(amino acids)=1553AA_BP=567
MAARRPRRGKSLAGFESLACSFPVVSRGFLASRSARSLSSEGGTMPDNRQPRNRQPRIRSGNEPRSAPAMEPDGRGAWAHSRAALDRLEK
LLRCSRCTNILREPVCLGGCEHIFCSNCVSDCIGTGCPVCYTPAWIQDLKINRQLDSMIQLCSKLRNLLHDNELSDLKEDKPRKSLFNDA
GNKKNSIKMWFSPRSKKVRYVVSKASVQTQPAIKKDASAQQDSYEFVSPSPPADVSERAKKASARSGKKQKKKTLAEINQKWNLEAEKED
GEFDSKEESKQKLVSFCSQPSVISSPQINGEIDLLASGSLTESECFGSLTEVSLPLAEQIESPDTKSRNEVVTPEKVCKNYLTSKKSLPL
ENNGKRGHHNRLSSPISKRCRTSILSTSGDFVKQTVPSENIPLPECSSPPSCKRKVGGTSGRKNSNMSDEFISLSPGTPPSTLSSSSYRR
VMSSPSAMKLLPNMAVKRNHRGETLLHIASIKGDIPSVEYLLQNGSDPNVKDHAGWTPLHEACNHGHLKVVELLLQHKALVNTTGYQNDS
PLHDAAKNGHVDIVKLLLSYGASRNAVRMFLLVGAPKANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKSHQWFG
ASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSQDIDADGQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLIS
DQVAEIVSKYDPNVYSIKYNNQLATRTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSLYNFTGEQMAAY
FGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYG
GEDKKGIVYIFNGRSTGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVYPSILN
QDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDE
SEFRDKLTPITIFMEYRLDYRTAADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVDSDQKKIYIGDDNPLTLIVKAQNQG
EGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNPMKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDK
VSPVVSHKVDLAVLAAVEIRGVSSPDHVFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAMLHLQWPYKYNNNTLLYILHYD
IDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSEGDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWT
ETFMNKENQNHSYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKRVR

--------------------------------------------------------------
>8979_8979_2_BARD1-ITGAV_BARD1_chr2_215632205_ENST00000260947_ITGAV_chr2_187466747_ENST00000374907_length(transcript)=8162nt_BP=1703nt
CCTCTGGCGGCCCGCCGTCCCAGACGCGGGAAGAGCTTGGCCGGTTTCGAGTCGCTGGCCTGCAGCTTCCCTGTGGTTTCCCGAGGCTTC
CTTGCTTCCCGCTCTGCGAGGAGCCTTTCATCCGAAGGCGGGACGATGCCGGATAATCGGCAGCCGAGGAACCGGCAGCCGAGGATCCGC
TCCGGGAACGAGCCTCGTTCCGCGCCCGCCATGGAACCGGATGGTCGCGGTGCCTGGGCCCACAGTCGCGCCGCGCTCGACCGCCTGGAG
AAGCTGCTGCGCTGCTCGCGTTGTACTAACATTCTGAGAGAGCCTGTGTGTTTAGGAGGATGTGAGCACATCTTCTGTAGTAATTGTGTA
AGTGACTGCATTGGAACTGGATGTCCAGTGTGTTACACCCCGGCCTGGATACAAGACTTGAAGATAAATAGACAACTGGACAGCATGATT
CAACTTTGTAGTAAGCTTCGAAATTTGCTACATGACAATGAGCTGTCAGATTTGAAAGAAGATAAACCTAGGAAAAGTTTGTTTAATGAT
GCAGGAAACAAGAAGAATTCAATTAAAATGTGGTTTAGCCCTCGAAGTAAGAAAGTCAGATATGTTGTGAGTAAAGCTTCAGTGCAAACC
CAGCCTGCAATAAAAAAAGATGCAAGTGCTCAGCAAGACTCATATGAATTTGTTTCCCCAAGTCCTCCTGCAGATGTTTCTGAGAGGGCT
AAAAAGGCTTCTGCAAGATCTGGAAAAAAGCAAAAAAAGAAAACTTTAGCTGAAATCAACCAAAAATGGAATTTAGAGGCAGAAAAAGAA
GATGGTGAATTTGACTCCAAAGAGGAATCTAAGCAAAAGCTGGTATCCTTCTGTAGCCAACCATCTGTTATCTCCAGTCCTCAGATAAAT
GGTGAAATAGACTTACTAGCAAGTGGCTCCTTGACAGAATCTGAATGTTTTGGAAGTTTAACTGAAGTCTCTTTACCATTGGCTGAGCAA
ATAGAGTCTCCAGACACTAAGAGCAGGAATGAAGTAGTGACTCCTGAGAAGGTCTGCAAAAATTATCTTACATCTAAGAAATCTTTGCCA
TTAGAAAATAATGGAAAACGTGGCCATCACAATAGACTTTCCAGTCCCATTTCTAAGAGATGTAGAACCAGCATTCTGAGCACCAGTGGA
GATTTTGTTAAGCAAACGGTGCCCTCAGAAAATATACCATTGCCTGAATGTTCTTCACCACCTTCATGCAAACGTAAAGTTGGTGGTACA
TCAGGGAGGAAAAACAGTAACATGTCCGATGAATTCATTAGTCTTTCACCAGGTACACCACCTTCTACATTAAGTAGTTCAAGTTACAGG
CGAGTGATGTCTAGTCCCTCAGCAATGAAGCTGTTGCCCAATATGGCTGTGAAAAGAAATCATAGAGGAGAGACTTTGCTCCATATTGCT
TCTATTAAGGGCGACATACCTTCTGTTGAATACCTTTTACAAAATGGAAGTGATCCAAATGTTAAAGACCATGCTGGATGGACACCATTG
CATGAAGCTTGCAATCATGGGCACCTGAAGGTAGTGGAATTATTGCTCCAGCATAAGGCATTGGTGAACACCACCGGGTATCAAAATGAC
TCACCACTTCACGATGCAGCCAAGAATGGGCATGTGGATATAGTCAAGCTGTTACTTTCCTATGGAGCCTCCAGAAATGCTGTCCGGATG
TTTCTTCTCGTGGGAGCTCCCAAAGCAAACACCACCCAGCCTGGGATTGTGGAAGGAGGGCAGGTCCTCAAATGTGACTGGTCTTCTACC
CGCCGGTGCCAGCCAATTGAATTTGATGCAACAGGCAATAGAGATTATGCCAAGGATGATCCATTGGAATTTAAGTCCCATCAGTGGTTT
GGAGCATCTGTGAGGTCGAAACAGGATAAAATTTTGGCCTGTGCCCCATTGTACCATTGGAGAACTGAGATGAAACAGGAGCGAGAGCCT
GTTGGAACATGCTTTCTTCAAGATGGAACAAAGACTGTTGAGTATGCTCCATGTAGATCACGTCAGCTTATTTCGGATCAAGTGGCAGAA
ATCGTATCTAAATACGACCCCAATGTTTACAGCATCAAGTATAATAACCAATTAGCAACTCGGACTGCACAAGCTATTTTTGATGACAGC
TATTTGGGTTATTCTGTGGCTGTCGGAGATTTCAATGGTGATGGCATAGATGACTTTGTTTCAGGAGTTCCAAGAGCAGCAAGGACTTTG
GGAATGGTTTATATTTATGATGGGAAGAACATGTCCTCCTTATACAATTTTACTGGCGAGCAGATGGCTGCATATTTCGGATTTTCTGTA
GCTGCCACTGACATTAATGGAGATGATTATGCAGATGTGTTTATTGGAGCACCTCTCTTCATGGATCGTGGCTCTGATGGCAAACTCCAA
GAGGTGGGGCAGGTCTCAGTGTCTCTACAGAGAGCTTCAGGAGACTTCCAGACGACAAAGCTGAATGGATTTGAGGTCTTTGCACGGTTT
GGCAGTGCCATAGCTCCTTTGGGAGATCTGGACCAGGATGGTTTCAATGATATTGCAATTGCTGCTCCATATGGGGGTGAAGATAAAAAA
GGAATTGTTTATATCTTCAATGGAAGATCAACAGGCTTGAACGCAGTCCCATCTCAAATCCTTGAAGGGCAGTGGGCTGCTCGAAGCATG
CCACCAAGCTTTGGCTATTCAATGAAAGGAGCCACAGATATAGACAAAAATGGATATCCAGACTTAATTGTAGGAGCTTTTGGTGTAGAT
CGAGCTATCTTATACAGGGCCAGACCAGTTATCACTGTAAATGCTGGTCTTGAAGTGTACCCTAGCATTTTAAATCAAGACAATAAAACC
TGCTCACTGCCTGGAACAGCTCTCAAAGTTTCCTGTTTTAATGTTAGGTTCTGCTTAAAGGCAGATGGCAAAGGAGTACTTCCCAGGAAA
CTTAATTTCCAGGTGGAACTTCTTTTGGATAAACTCAAGCAAAAGGGAGCAATTCGACGAGCACTGTTTCTCTACAGCAGGTCCCCAAGT
CACTCCAAGAACATGACTATTTCAAGGGGGGGACTGATGCAGTGTGAGGAATTGATAGCGTATCTGCGGGATGAATCTGAATTTAGAGAC
AAACTCACTCCAATTACTATTTTTATGGAATATCGGTTGGATTATAGAACAGCTGCTGATACAACAGGCTTGCAACCCATTCTTAACCAG
TTCACGCCTGCTAACATTAGTCGACAGGCTCACATTCTACTTGACTGTGGTGAAGACAATGTCTGTAAACCCAAGCTGGAAGTTTCTGTA
GATAGTGATCAAAAGAAGATCTATATTGGGGATGACAACCCTCTGACATTGATTGTTAAGGCTCAGAATCAAGGAGAAGGTGCCTACGAA
GCTGAGCTCATCGTTTCCATTCCACTGCAGGCTGATTTCATCGGGGTTGTCCGAAACAATGAAGCCTTAGCAAGACTTTCCTGTGCATTT
AAGACAGAAAACCAAACTCGCCAGGTGGTATGTGACCTTGGAAACCCAATGAAGGCTGGAACTCAACTCTTAGCTGGTCTTCGTTTCAGT
GTGCACCAGCAGTCAGAGATGGATACTTCTGTGAAATTTGACTTACAAATCCAAAGCTCAAATCTATTTGACAAAGTAAGCCCAGTTGTA
TCTCACAAAGTTGATCTTGCTGTTTTAGCTGCAGTTGAGATAAGAGGAGTCTCGAGTCCTGATCATGTCTTTCTTCCGATTCCAAACTGG
GAGCACAAGGAGAACCCTGAGACTGAAGAAGATGTTGGGCCAGTTGTTCAGCACATCTATGAGCTGAGAAACAATGGTCCAAGTTCATTC
AGCAAGGCAATGCTCCATCTTCAGTGGCCTTACAAATATAATAATAACACTCTGTTGTATATCCTTCATTATGATATTGATGGACCAATG
AACTGCACTTCAGATATGGAGATCAACCCTTTGAGAATTAAGATCTCATCTTTGCAAACAACTGAAAAGAATGACACGGTTGCCGGGCAA
GGTGAGCGGGACCATCTCATCACTAAGCGGGATCTTGCCCTCAGTGAAGGAGATATTCACACTTTGGGTTGTGGAGTTGCTCAGTGCTTG
AAGATTGTCTGCCAAGTTGGGAGATTAGACAGAGGAAAGAGTGCAATCTTGTACGTAAAGTCATTACTGTGGACTGAGACTTTTATGAAT
AAAGAAAATCAGAATCATTCCTATTCTCTGAAGTCGTCTGCTTCATTTAATGTCATAGAGTTTCCTTATAAGAATCTTCCAATTGAGGAT
ATCACCAACTCCACATTGGTTACCACTAATGTCACCTGGGGCATTCAGCCAGCGCCCATGCCTGTGCCTGTGTGGGTGATCATTTTAGCA
GTTCTAGCAGGATTGTTGCTACTGGCTGTTTTGGTATTTGTAATGTACAGGATGGGCTTTTTTAAACGGGTCCGGCCACCTCAAGAAGAA
CAAGAAAGGGAGCAGCTTCAACCTCATGAAAATGGTGAAGGAAACTCAGAAACTTAACTGCAGTTTTTAAGTTATGCTACATCTTGACCC
ACTAGAATTAGCAACTTTATTATAGATTTAAACTTTCTTCATGAGGAGTAAAAATCCAAGGCTTTACTGCTGATAGTGCTAATTGGCATT
AACCACAAAATGAGAATTATATTTGTCAACCTTCTCCTTATAAATAAGTTCAGACATACATTTAATAACATAGGGTGACTTGTGTTTTTA
GGTATTTAAATAATAAAATTTCAAGGGATAGTTTTTATTCAATGTATATAAGACAGGTAGTGCCTGATTTACTACTTTATATAAAATAGT
ACCTCCTTCAGTTACTGTTTCTGATTTAATGTACGGAACTTTATTTGTTGTTGTTGTTGTTGTTGTTGTTGTTGTTTTAAAGCAGTCCAA
ATTTGGACCTTAGCAATCATGTCTTTTGTATAGGTACTTAATGTTAATACATATTACACTACAGTTTACTTTTCAGAATACTAAAGACTT
TATAACTGCATGAACTTGGATTTTTTTAATCACTCATATGGTAGAATTTTATAAACACATACATGATACCATCCAAATTCTTGCTTTTAA
TAACAAAGGTACAATATTTTGTTTTAGTATGAAAATCTGGTAGATCCTATTACACTTCTGTTTATATTAAATCCACAATATTTTATTACA
TTTTTAACTTGTATAAATTTTAGGTCAAATCCTTCAAGCCAACCTATACTAAAAATTAGTTCCATAATCACAAATGGCTCTTTTGTGTAA
TTGTTTAATTTCACCTGAATATCATAATGCTTAAAGCCATATGGAGTTGGAAATTATTTCCAAAGCATATTTATTCCATTGTTTTAGTCT
GGCTATTTACAGTATAAAAAAAGCATTTTTATTAAAATACTGTGTAGTTCTTTGAGATAGTTGCTTATGCATATAGTAAGTATTACATTC
TTAGAGTAGAGCAGAGTTTTTAGTTAGTATTAATTTATTTTCCTCCATTCATGTACTTTTCCTTATATTTCCAAAACTGTTACTGAGAAT
GGGTCAAGATCAGTGAGAAATCTTTACAGTTGACAGGAACCTGGACCCCTTACCCCAACTTTATGAGTAATGCTTGGAATAAAAACTCTT
AAGGCAACTCACTGATTTACTTCTAGCAATAGCATGATGTTACAGGAATATTACCTCTGTTTAAGCAAGGTAATGTGTAAAATCAGTCTC
GGCTGTCAGAATAACTTCTAAAAGGTATTTTTATAAGCAGTTCAAGTTACTGAAAACCTTTTAAACCTTTCTGAAGTTCGTTAGTATAAA
TTACTTTTCTAGGATTATTAATAAAAGCCACATAGGTGGCAAGTTGTAGTTTTATATGGCTCTGTAGAGTGGTGAACCTTCTAGAGGAAT
ATATGATTTATTCACAGTTCCTCAAGGCCTGGGGATGATGATCAGTTATACCTATTTTTGTGCAATTACATCATGTTGTACATTAGAAAT
GGAGAGTTTAATAGCTCTTTAACTGCTGTCCTCATTAGGTAATGATAAATATTTCCCTTAAATAATTGACTATTTTGCTGTGTTTTAAAA
ATGATTGAAATTTATCTTGCCATATCTCATAATTTCATGCACAAGTTGACTGAGCTAATCTTGAGAATATATTCGTAAAATAGGAGCACA
TTTAGTTGAGGTATACAAGGTAGGACTCTAGACAAAACCTTCTATTTTAGCTTTAGTGAATTTCAAAAGTAATGGGTCTTGGAGTATAGA
TTTTTATTAGTAGCTTGAAAGAGCTTAATCATATGCAGTAAGTATTTTTATTACCAATAAATTTAAAATTTTTTAAGAAAAATATTTTTA
TCCTAGGGCCAAGTGTTGCCTGCCACCAATCAGTAAGTTAGTCTATAACAAATTTTACCCTAACAGTTTTACCACCTAGTAACAGTCATT
TCTGAAAATATGTTGGATAGAAAGTCACTCTTTGGCAAAAGTGTTAGAATTTGCTTTTGTGCCATCTATTCCTTTTATGGCATCTATCTT
GAAAGTAATCTTGTATTGGAGATTGAAAGATGCTGTAATTTAGAAATTAACATGATATCTTAAATTACCTTTATGAAATATAGTTTTGTA
TAATAGCATAGATTTTCCTTCAAAAAATGAACATTTATATATCTACAAAAATATGGAGAAGAGTAATTTGAAAGCCTACTTTCTGAAGAA
AATGGTGGGATTTTTTTTTATCATGATTAAATATCAAAAAATTGCCCTATGAAAACTTTAAATCTCTAAAACATTTGAAATACTACCATA
TTTGTGATTTATTGAGAATAAAAATCCATTTTGAAATGTAAAATTTTTATGATCTGATTCAGTTTTAAGAAAACATGAATGAACTAGAAG
ATATTAAAAACATTTGACATTGGTAAGAAATATTGATACTGATATTGATTTTTATATAGGTATTTATTTCAGAATTGATATTTTGAGAAA
AATACATGTGAGTCATTTTTTCTGTTTCTCTTTTCTCTTAACGATTATCACTGTAATTCTGAATCTGAAAGGTAAAACAATTAGTCAAAA
TATTATTGCCATCATTCTACCTGTGTTATGAAACTACTTATTCATAGTTAATTCTCATTAACACTTACATTTCCATAAAGAAAACTCAAG
TATTAATAAAAGAGACTTTACTGGCTTAAGAGGGCTGTGAAAGATTTTTGATAGTGAATCATGACCCTAAGGGAGAGATTTGTGTGATAA
AAGTATTGTATATAATAGATCAGCGATTTTTGTAAGGCAAACAGAATTTGTAAGTTGGCAGATCTTCCTAAGTTGCAAAATGTAATGATG
AGCTTGGTGGAGAAGAATGAGTCGTTCTTGGAATACCTATGTGCAGCCACTACCCATCTCAATGTCACCTTGTTTGCATTCTTGGATAGC
TTGTATATGTAGTAGTTTGATGAATAATTTAAAGAAAAACACCTAAAATTTGAAAAATGATTGTAGGATCAAAAAAGGCAGATGAAATTA
CTTAATACTCAGTGTTTTGGAGAGTATTCCTTTTAGTTTGTTGGTTGGCTGGTTTGAACGATAGAAATATGCAGCATGCAATATATGCTT
ATATTTCATTTTAATTTCTGATATATAATGAACTTCTTGGGAGAGGTACTGAATCTTTGATGTTTTTTGTCATTGTTCTCAAGTGCAATA
TAACAATGTAACCAAATCTAGATAATTTCAAAGTTGTCATTAATTTAGTAAGCCTAATATAAACAAATATTTGTATTATTTTTGTTAGCA
GGAAAGAGTGATTAAGTGAGGTTATTTACCCCTAAATGGTCCATTCTGCATTGTATTTCAGGCTGGAAATGAATTATTCTTTACCAGTTT
TGAAACACTTTGAAATATCCTAAGGTAACTTGGAAGCTGTGTAGTATATCAAATTAATTTGCTACCTAATAACATAGAAAGTAAATATCT
TTGTGGTCACCCACATTGGGTGAGACAGAAAATGAATCTGTTCTAAAATTTGTAATTTGCTAACTTGATTTGAGTTAGTGAAAACTGGTA

>8979_8979_2_BARD1-ITGAV_BARD1_chr2_215632205_ENST00000260947_ITGAV_chr2_187466747_ENST00000374907_length(amino acids)=1517AA_BP=567
MAARRPRRGKSLAGFESLACSFPVVSRGFLASRSARSLSSEGGTMPDNRQPRNRQPRIRSGNEPRSAPAMEPDGRGAWAHSRAALDRLEK
LLRCSRCTNILREPVCLGGCEHIFCSNCVSDCIGTGCPVCYTPAWIQDLKINRQLDSMIQLCSKLRNLLHDNELSDLKEDKPRKSLFNDA
GNKKNSIKMWFSPRSKKVRYVVSKASVQTQPAIKKDASAQQDSYEFVSPSPPADVSERAKKASARSGKKQKKKTLAEINQKWNLEAEKED
GEFDSKEESKQKLVSFCSQPSVISSPQINGEIDLLASGSLTESECFGSLTEVSLPLAEQIESPDTKSRNEVVTPEKVCKNYLTSKKSLPL
ENNGKRGHHNRLSSPISKRCRTSILSTSGDFVKQTVPSENIPLPECSSPPSCKRKVGGTSGRKNSNMSDEFISLSPGTPPSTLSSSSYRR
VMSSPSAMKLLPNMAVKRNHRGETLLHIASIKGDIPSVEYLLQNGSDPNVKDHAGWTPLHEACNHGHLKVVELLLQHKALVNTTGYQNDS
PLHDAAKNGHVDIVKLLLSYGASRNAVRMFLLVGAPKANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKSHQWFG
ASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSRQLISDQVAEIVSKYDPNVYSIKYNNQLATRTAQAIFDDSY
LGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSLYNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQE
VGQVSVSLQRASGDFQTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPSQILEGQWAARSMP
PSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKL
NFQVELLLDKLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYRTAADTTGLQPILNQF
TPANISRQAHILLDCGEDNVCKPKLEVSVDSDQKKIYIGDDNPLTLIVKAQNQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFK
TENQTRQVVCDLGNPMKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSPDHVFLPIPNWE
HKENPETEEDVGPVVQHIYELRNNGPSSFSKAMLHLQWPYKYNNNTLLYILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQG
ERDHLITKRDLALSEGDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVIEFPYKNLPIEDI

--------------------------------------------------------------
>8979_8979_3_BARD1-ITGAV_BARD1_chr2_215632205_ENST00000260947_ITGAV_chr2_187466747_ENST00000433736_length(transcript)=4814nt_BP=1703nt
CCTCTGGCGGCCCGCCGTCCCAGACGCGGGAAGAGCTTGGCCGGTTTCGAGTCGCTGGCCTGCAGCTTCCCTGTGGTTTCCCGAGGCTTC
CTTGCTTCCCGCTCTGCGAGGAGCCTTTCATCCGAAGGCGGGACGATGCCGGATAATCGGCAGCCGAGGAACCGGCAGCCGAGGATCCGC
TCCGGGAACGAGCCTCGTTCCGCGCCCGCCATGGAACCGGATGGTCGCGGTGCCTGGGCCCACAGTCGCGCCGCGCTCGACCGCCTGGAG
AAGCTGCTGCGCTGCTCGCGTTGTACTAACATTCTGAGAGAGCCTGTGTGTTTAGGAGGATGTGAGCACATCTTCTGTAGTAATTGTGTA
AGTGACTGCATTGGAACTGGATGTCCAGTGTGTTACACCCCGGCCTGGATACAAGACTTGAAGATAAATAGACAACTGGACAGCATGATT
CAACTTTGTAGTAAGCTTCGAAATTTGCTACATGACAATGAGCTGTCAGATTTGAAAGAAGATAAACCTAGGAAAAGTTTGTTTAATGAT
GCAGGAAACAAGAAGAATTCAATTAAAATGTGGTTTAGCCCTCGAAGTAAGAAAGTCAGATATGTTGTGAGTAAAGCTTCAGTGCAAACC
CAGCCTGCAATAAAAAAAGATGCAAGTGCTCAGCAAGACTCATATGAATTTGTTTCCCCAAGTCCTCCTGCAGATGTTTCTGAGAGGGCT
AAAAAGGCTTCTGCAAGATCTGGAAAAAAGCAAAAAAAGAAAACTTTAGCTGAAATCAACCAAAAATGGAATTTAGAGGCAGAAAAAGAA
GATGGTGAATTTGACTCCAAAGAGGAATCTAAGCAAAAGCTGGTATCCTTCTGTAGCCAACCATCTGTTATCTCCAGTCCTCAGATAAAT
GGTGAAATAGACTTACTAGCAAGTGGCTCCTTGACAGAATCTGAATGTTTTGGAAGTTTAACTGAAGTCTCTTTACCATTGGCTGAGCAA
ATAGAGTCTCCAGACACTAAGAGCAGGAATGAAGTAGTGACTCCTGAGAAGGTCTGCAAAAATTATCTTACATCTAAGAAATCTTTGCCA
TTAGAAAATAATGGAAAACGTGGCCATCACAATAGACTTTCCAGTCCCATTTCTAAGAGATGTAGAACCAGCATTCTGAGCACCAGTGGA
GATTTTGTTAAGCAAACGGTGCCCTCAGAAAATATACCATTGCCTGAATGTTCTTCACCACCTTCATGCAAACGTAAAGTTGGTGGTACA
TCAGGGAGGAAAAACAGTAACATGTCCGATGAATTCATTAGTCTTTCACCAGGTACACCACCTTCTACATTAAGTAGTTCAAGTTACAGG
CGAGTGATGTCTAGTCCCTCAGCAATGAAGCTGTTGCCCAATATGGCTGTGAAAAGAAATCATAGAGGAGAGACTTTGCTCCATATTGCT
TCTATTAAGGGCGACATACCTTCTGTTGAATACCTTTTACAAAATGGAAGTGATCCAAATGTTAAAGACCATGCTGGATGGACACCATTG
CATGAAGCTTGCAATCATGGGCACCTGAAGGTAGTGGAATTATTGCTCCAGCATAAGGCATTGGTGAACACCACCGGGTATCAAAATGAC
TCACCACTTCACGATGCAGCCAAGAATGGGCATGTGGATATAGTCAAGCTGTTACTTTCCTATGGAGCCTCCAGAAATGCTGTCCGGATG
TTTCTTCTCGTGGGAGCTCCCAAAGCAAACACCACCCAGCCTGGGATTGTGGAAGGAGGGCAGGTCCTCAAATGTGACTGGTCTTCTACC
CGCCGGTGCCAGCCAATTGAATTTGATGCAACAGGCAATAGAGATTATGCCAAGGATGATCCATTGGAATTTAAGTCCCATCAGTGGTTT
GGAGCATCTGTGAGGTCGAAACAGGATAAAATTTTGGCCTGTGCCCCATTGTACCATTGGAGAACTGAGATGAAACAGGAGCGAGAGCCT
GTTGGAACATGCTTTCTTCAAGATGGAACAAAGACTGTTGAGTATGCTCCATGTAGATCACAAGATATTGATGCTGATGGACAGGGATTT
TGTCAAGGAGGATTCAGCATTGATTTTACTAAAGCTGACAGAGTACTTCTTGGTGGTCCTGGTAGCTTTTATTGGCAAGGTCAGCTTATT
TCGGATCAAGTGGCAGAAATCGTATCTAAATACGACCCCAATGTTTACAGCATCAAGTATAATAACCAATTAGCAACTCGGACTGCACAA
GCTATTTTTGATGACAGCTATTTGGGTTATTCTGTGGCTGTCGGAGATTTCAATGGTGATGGCATAGATGACTTTGTTTCAGGAGTTCCA
AGAGCAGCAAGGACTTTGGGAATGGTTTATATTTATGATGGGAAGAACATGTCCTCCTTATACAATTTTACTGGCGAGCAGATGGCTGCA
TATTTCGGATTTTCTGTAGCTGCCACTGACATTAATGGAGATGATTATGCAGATGTGTTTATTGGAGCACCTCTCTTCATGGATCGTGGC
TCTGATGGCAAACTCCAAGAGGTGGGGCAGGTCTCAGTGTCTCTACAGAGAGCTTCAGGAGACTTCCAGACGACAAAGCTGAATGGATTT
GAGGTCTTTGCACGGTTTGGCAGTGCCATAGCTCCTTTGGGAGATCTGGACCAGGATGGTTTCAATGATATTGCAATTGCTGCTCCATAT
GGGGGTGAAGATAAAAAAGGAATTGTTTATATCTTCAATGGAAGATCAACAGGCTTGAACGCAGTCCCATCTCAAATCCTTGAAGGGCAG
TGGGCTGCTCGAAGCATGCCACCAAGCTTTGGCTATTCAATGAAAGGAGCCACAGATATAGACAAAAATGGATATCCAGACTTAATTGTA
GGAGCTTTTGGTGTAGATCGAGCTATCTTATACAGGGCCAGACCAGTTATCACTGTAAATGCTGGTCTTGAAGTGTACCCTAGCATTTTA
AATCAAGACAATAAAACCTGCTCACTGCCTGGAACAGCTCTCAAAGTTTCCTGTTTTAATGTTAGGTTCTGCTTAAAGGCAGATGGCAAA
GGAGTACTTCCCAGGAAACTTAATTTCCAGGTGGAACTTCTTTTGGATAAACTCAAGCAAAAGGGAGCAATTCGACGAGCACTGTTTCTC
TACAGCAGGTCCCCAAGTCACTCCAAGAACATGACTATTTCAAGGGGGGGACTGATGCAGTGTGAGGAATTGATAGCGTATCTGCGGGAT
GAATCTGAATTTAGAGACAAACTCACTCCAATTACTATTTTTATGGAATATCGGTTGGATTATAGAACAGCTGCTGATACAACAGGCTTG
CAACCCATTCTTAACCAGTTCACGCCTGCTAACATTAGTCGACAGGCTCACATTCTACTTGACTGTGGTGAAGACAATGTCTGTAAACCC
AAGCTGGAAGTTTCTGTAGATAGTGATCAAAAGAAGATCTATATTGGGGATGACAACCCTCTGACATTGATTGTTAAGGCTCAGAATCAA
GGAGAAGGTGCCTACGAAGCTGAGCTCATCGTTTCCATTCCACTGCAGGCTGATTTCATCGGGGTTGTCCGAAACAATGAAGCCTTAGCA
AGACTTTCCTGTGCATTTAAGACAGAAAACCAAACTCGCCAGGTGGTATGTGACCTTGGAAACCCAATGAAGGCTGGAACTCAACTCTTA
GCTGGTCTTCGTTTCAGTGTGCACCAGCAGTCAGAGATGGATACTTCTGTGAAATTTGACTTACAAATCCAAAGCTCAAATCTATTTGAC
AAAGTAAGCCCAGTTGTATCTCACAAAGTTGATCTTGCTGTTTTAGCTGCAGTTGAGATAAGAGGAGTCTCGAGTCCTGATCATGTCTTT
CTTCCGATTCCAAACTGGGAGCACAAGGAGAACCCTGAGACTGAAGAAGATGTTGGGCCAGTTGTTCAGCACATCTATGAGCTGAGAAAC
AATGGTCCAAGTTCATTCAGCAAGGCAATGCTCCATCTTCAGTGGCCTTACAAATATAATAATAACACTCTGTTGTATATCCTTCATTAT
GATATTGATGGACCAATGAACTGCACTTCAGATATGGAGATCAACCCTTTGAGAATTAAGATCTCATCTTTGCAAACAACTGAAAAGAAT
GACACGGTTGCCGGGCAAGGTGAGCGGGACCATCTCATCACTAAGCGGGATCTTGCCCTCAGTGAAGGAGATATTCACACTTTGGGTTGT
GGAGTTGCTCAGTGCTTGAAGATTGTCTGCCAAGTTGGGAGATTAGACAGAGGAAAGAGTGCAATCTTGTACGTAAAGTCATTACTGTGG
ACTGAGACTTTTATGAATAAAGAAAATCAGAATCATTCCTATTCTCTGAAGTCGTCTGCTTCATTTAATGTCATAGAGTTTCCTTATAAG
AATCTTCCAATTGAGGATATCACCAACTCCACATTGGTTACCACTAATGTCACCTGGGGCATTCAGCCAGCGCCCATGCCTGTGCCTGTG
TGGGTGATCATTTTAGCAGTTCTAGCAGGATTGTTGCTACTGGCTGTTTTGGTATTTGTAATGTACAGGATGGGCTTTTTTAAACGGGTC
CGGCCACCTCAAGAAGAACAAGAAAGGGAGCAGCTTCAACCTCATGAAAATGGTGAAGGAAACTCAGAAACTTAACTGCAGTTTTTAAGT
TATGCTACATCTTGACCCACTAGAATTAGCAACTTTATTATAGATTTAAACTTTCTTCATGAGGAGTAAAAATCCAAGGCTTTACTGCTG

>8979_8979_3_BARD1-ITGAV_BARD1_chr2_215632205_ENST00000260947_ITGAV_chr2_187466747_ENST00000433736_length(amino acids)=1553AA_BP=567
MAARRPRRGKSLAGFESLACSFPVVSRGFLASRSARSLSSEGGTMPDNRQPRNRQPRIRSGNEPRSAPAMEPDGRGAWAHSRAALDRLEK
LLRCSRCTNILREPVCLGGCEHIFCSNCVSDCIGTGCPVCYTPAWIQDLKINRQLDSMIQLCSKLRNLLHDNELSDLKEDKPRKSLFNDA
GNKKNSIKMWFSPRSKKVRYVVSKASVQTQPAIKKDASAQQDSYEFVSPSPPADVSERAKKASARSGKKQKKKTLAEINQKWNLEAEKED
GEFDSKEESKQKLVSFCSQPSVISSPQINGEIDLLASGSLTESECFGSLTEVSLPLAEQIESPDTKSRNEVVTPEKVCKNYLTSKKSLPL
ENNGKRGHHNRLSSPISKRCRTSILSTSGDFVKQTVPSENIPLPECSSPPSCKRKVGGTSGRKNSNMSDEFISLSPGTPPSTLSSSSYRR
VMSSPSAMKLLPNMAVKRNHRGETLLHIASIKGDIPSVEYLLQNGSDPNVKDHAGWTPLHEACNHGHLKVVELLLQHKALVNTTGYQNDS
PLHDAAKNGHVDIVKLLLSYGASRNAVRMFLLVGAPKANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKSHQWFG
ASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSQDIDADGQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLIS
DQVAEIVSKYDPNVYSIKYNNQLATRTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSLYNFTGEQMAAY
FGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYG
GEDKKGIVYIFNGRSTGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVYPSILN
QDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLDKLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDE
SEFRDKLTPITIFMEYRLDYRTAADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKLEVSVDSDQKKIYIGDDNPLTLIVKAQNQG
EGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNPMKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDK
VSPVVSHKVDLAVLAAVEIRGVSSPDHVFLPIPNWEHKENPETEEDVGPVVQHIYELRNNGPSSFSKAMLHLQWPYKYNNNTLLYILHYD
IDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSEGDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLLWT
ETFMNKENQNHSYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKRVR

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for BARD1-ITGAV


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
HgeneBARD1chr2:215632205chr2:187466747ENST00000260947-61126_119522.6666666666666778.0BRCA1


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for BARD1-ITGAV


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for BARD1-ITGAV


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneBARD1C0346153Breast Cancer, Familial11CLINGEN
HgeneBARD1C0009405Hereditary Nonpolyposis Colorectal Neoplasms4CLINGEN
HgeneBARD1C1112155Hereditary non-polyposis colorectal cancer syndrome4CLINGEN
HgeneBARD1C1333990Hereditary Nonpolyposis Colorectal Cancer4CLINGEN
HgeneBARD1C1333991Hereditary Non-Polyposis Colon Cancer Type 24CLINGEN
HgeneBARD1C2936783Colorectal cancer, hereditary nonpolyposis, type 14CLINGEN
HgeneBARD1C0027819Neuroblastoma2CTD_human
HgeneBARD1C0677776Hereditary Breast and Ovarian Cancer Syndrome1ORPHANET
TgeneC0038454Cerebrovascular accident1CTD_human
TgeneC0751956Acute Cerebrovascular Accidents1CTD_human
TgeneC2937358Cerebral Hemorrhage1CTD_human