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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Fusion gene:SENP2-MSH5 (FusionGDB2 ID:HG59343TG4439)

Fusion Gene Summary for SENP2-MSH5

check button Fusion gene summary
Fusion gene informationFusion gene name: SENP2-MSH5
Fusion gene ID: hg59343tg4439
HgeneTgene
Gene symbol

SENP2

MSH5

Gene ID

59343

4439

Gene nameSUMO specific peptidase 2mutS homolog 5
SynonymsAXAM2|SMT3IP2G7|MUTSH5|NG23|POF13
Cytomap('SENP2')('MSH5')

3q27.2

6p21.33

Type of geneprotein-codingprotein-coding
Descriptionsentrin-specific protease 2SMT3-specific isopeptidase 2SUMO1/sentrin/SMT3 specific peptidase 2SUMO1/sentrin/SMT3 specific protease 2sentrin (SUMO1) specific peptidase 2sentrin/SUMO-specific protease SENP2mutS protein homolog 5
Modification date2020031320200313
UniProtAcc.

O43196

Ensembl transtripts involved in fusion geneENST00000465201, ENST00000296257, 
ENST00000545472, ENST00000427465, 
Fusion gene scores* DoF score13 X 12 X 10=15605 X 6 X 4=120
# samples 165
** MAII scorelog2(16/1560*10)=-3.28540221886225
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(5/120*10)=-1.26303440583379
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: SENP2 [Title/Abstract] AND MSH5 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSENP2(185316812)-MSH5(31726543), # samples:2
Anticipated loss of major functional domain due to fusion event.SENP2-MSH5 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
SENP2-MSH5 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
SENP2-MSH5 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
SENP2-MSH5 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneSENP2

GO:0016926

protein desumoylation

20194620

HgeneSENP2

GO:0031397

negative regulation of protein ubiquitination

22028379


check buttonFusion gene breakpoints across SENP2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across MSH5 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4ACCTCGA-OR-A5K5-01ASENP2chr3

185316812

-MSH5chr6

31726543

+
ChimerDB4ACCTCGA-OR-A5K5-01ASENP2chr3

185316812

+MSH5chr6

31726543

+
ChimerDB4ACCTCGA-OR-A5K5-01ASENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+


Top

Fusion Gene ORF analysis for SENP2-MSH5

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000465201ENST00000375703SENP2chr3

185316812

+MSH5chr6

31726543

+
3UTR-3CDSENST00000465201ENST00000375740SENP2chr3

185316812

+MSH5chr6

31726543

+
3UTR-3CDSENST00000465201ENST00000375742SENP2chr3

185316812

+MSH5chr6

31726543

+
3UTR-3CDSENST00000465201ENST00000375750SENP2chr3

185316812

+MSH5chr6

31726543

+
3UTR-3CDSENST00000465201ENST00000375755SENP2chr3

185316812

+MSH5chr6

31726543

+
3UTR-3CDSENST00000465201ENST00000431848SENP2chr3

185316812

+MSH5chr6

31726543

+
3UTR-3CDSENST00000465201ENST00000534153SENP2chr3

185316812

+MSH5chr6

31726543

+
3UTR-3UTRENST00000465201ENST00000457917SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
3UTR-3UTRENST00000465201ENST00000490125SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
3UTR-intronENST00000465201ENST00000375703SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
3UTR-intronENST00000465201ENST00000375740SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
3UTR-intronENST00000465201ENST00000375742SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
3UTR-intronENST00000465201ENST00000375750SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
3UTR-intronENST00000465201ENST00000375755SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
3UTR-intronENST00000465201ENST00000395853SENP2chr3

185316812

+MSH5chr6

31726543

+
3UTR-intronENST00000465201ENST00000395853SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
3UTR-intronENST00000465201ENST00000414412SENP2chr3

185316812

+MSH5chr6

31726543

+
3UTR-intronENST00000465201ENST00000414412SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
3UTR-intronENST00000465201ENST00000416549SENP2chr3

185316812

+MSH5chr6

31726543

+
3UTR-intronENST00000465201ENST00000416549SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
3UTR-intronENST00000465201ENST00000419269SENP2chr3

185316812

+MSH5chr6

31726543

+
3UTR-intronENST00000465201ENST00000419269SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
3UTR-intronENST00000465201ENST00000427735SENP2chr3

185316812

+MSH5chr6

31726543

+
3UTR-intronENST00000465201ENST00000427735SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
3UTR-intronENST00000465201ENST00000430216SENP2chr3

185316812

+MSH5chr6

31726543

+
3UTR-intronENST00000465201ENST00000430216SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
3UTR-intronENST00000465201ENST00000431848SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
3UTR-intronENST00000465201ENST00000435700SENP2chr3

185316812

+MSH5chr6

31726543

+
3UTR-intronENST00000465201ENST00000435700SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
3UTR-intronENST00000465201ENST00000436004SENP2chr3

185316812

+MSH5chr6

31726543

+
3UTR-intronENST00000465201ENST00000436004SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
3UTR-intronENST00000465201ENST00000436192SENP2chr3

185316812

+MSH5chr6

31726543

+
3UTR-intronENST00000465201ENST00000436192SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
3UTR-intronENST00000465201ENST00000436559SENP2chr3

185316812

+MSH5chr6

31726543

+
3UTR-intronENST00000465201ENST00000436559SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
3UTR-intronENST00000465201ENST00000439816SENP2chr3

185316812

+MSH5chr6

31726543

+
3UTR-intronENST00000465201ENST00000439816SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
3UTR-intronENST00000465201ENST00000441395SENP2chr3

185316812

+MSH5chr6

31726543

+
3UTR-intronENST00000465201ENST00000441395SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
3UTR-intronENST00000465201ENST00000441401SENP2chr3

185316812

+MSH5chr6

31726543

+
3UTR-intronENST00000465201ENST00000441401SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
3UTR-intronENST00000465201ENST00000443040SENP2chr3

185316812

+MSH5chr6

31726543

+
3UTR-intronENST00000465201ENST00000443040SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
3UTR-intronENST00000465201ENST00000448169SENP2chr3

185316812

+MSH5chr6

31726543

+
3UTR-intronENST00000465201ENST00000448169SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
3UTR-intronENST00000465201ENST00000448617SENP2chr3

185316812

+MSH5chr6

31726543

+
3UTR-intronENST00000465201ENST00000448617SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
3UTR-intronENST00000465201ENST00000456839SENP2chr3

185316812

+MSH5chr6

31726543

+
3UTR-intronENST00000465201ENST00000456839SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
3UTR-intronENST00000465201ENST00000457742SENP2chr3

185316812

+MSH5chr6

31726543

+
3UTR-intronENST00000465201ENST00000457742SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
3UTR-intronENST00000465201ENST00000457917SENP2chr3

185316812

+MSH5chr6

31726543

+
3UTR-intronENST00000465201ENST00000458144SENP2chr3

185316812

+MSH5chr6

31726543

+
3UTR-intronENST00000465201ENST00000458144SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
3UTR-intronENST00000465201ENST00000460275SENP2chr3

185316812

+MSH5chr6

31726543

+
3UTR-intronENST00000465201ENST00000460275SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
3UTR-intronENST00000465201ENST00000473342SENP2chr3

185316812

+MSH5chr6

31726543

+
3UTR-intronENST00000465201ENST00000473342SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
3UTR-intronENST00000465201ENST00000478326SENP2chr3

185316812

+MSH5chr6

31726543

+
3UTR-intronENST00000465201ENST00000478326SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
3UTR-intronENST00000465201ENST00000480915SENP2chr3

185316812

+MSH5chr6

31726543

+
3UTR-intronENST00000465201ENST00000480915SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
3UTR-intronENST00000465201ENST00000482280SENP2chr3

185316812

+MSH5chr6

31726543

+
3UTR-intronENST00000465201ENST00000482280SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
3UTR-intronENST00000465201ENST00000486924SENP2chr3

185316812

+MSH5chr6

31726543

+
3UTR-intronENST00000465201ENST00000486924SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
3UTR-intronENST00000465201ENST00000490125SENP2chr3

185316812

+MSH5chr6

31726543

+
3UTR-intronENST00000465201ENST00000497157SENP2chr3

185316812

+MSH5chr6

31726543

+
3UTR-intronENST00000465201ENST00000497157SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
3UTR-intronENST00000465201ENST00000534153SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
3UTR-intronENST00000465201ENST00000549604SENP2chr3

185316812

+MSH5chr6

31726543

+
3UTR-intronENST00000465201ENST00000549604SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
3UTR-intronENST00000465201ENST00000549746SENP2chr3

185316812

+MSH5chr6

31726543

+
3UTR-intronENST00000465201ENST00000549746SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
3UTR-intronENST00000465201ENST00000578225SENP2chr3

185316812

+MSH5chr6

31726543

+
3UTR-intronENST00000465201ENST00000578225SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
5CDS-3UTRENST00000296257ENST00000457917SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
5CDS-3UTRENST00000296257ENST00000490125SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
5CDS-3UTRENST00000545472ENST00000457917SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
5CDS-3UTRENST00000545472ENST00000490125SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
5CDS-intronENST00000296257ENST00000375703SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
5CDS-intronENST00000296257ENST00000375740SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
5CDS-intronENST00000296257ENST00000375742SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
5CDS-intronENST00000296257ENST00000375750SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
5CDS-intronENST00000296257ENST00000375755SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
5CDS-intronENST00000296257ENST00000395853SENP2chr3

185316812

+MSH5chr6

31726543

+
5CDS-intronENST00000296257ENST00000395853SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
5CDS-intronENST00000296257ENST00000414412SENP2chr3

185316812

+MSH5chr6

31726543

+
5CDS-intronENST00000296257ENST00000414412SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
5CDS-intronENST00000296257ENST00000416549SENP2chr3

185316812

+MSH5chr6

31726543

+
5CDS-intronENST00000296257ENST00000416549SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
5CDS-intronENST00000296257ENST00000419269SENP2chr3

185316812

+MSH5chr6

31726543

+
5CDS-intronENST00000296257ENST00000419269SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
5CDS-intronENST00000296257ENST00000427735SENP2chr3

185316812

+MSH5chr6

31726543

+
5CDS-intronENST00000296257ENST00000427735SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
5CDS-intronENST00000296257ENST00000430216SENP2chr3

185316812

+MSH5chr6

31726543

+
5CDS-intronENST00000296257ENST00000430216SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
5CDS-intronENST00000296257ENST00000431848SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
5CDS-intronENST00000296257ENST00000435700SENP2chr3

185316812

+MSH5chr6

31726543

+
5CDS-intronENST00000296257ENST00000435700SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
5CDS-intronENST00000296257ENST00000436004SENP2chr3

185316812

+MSH5chr6

31726543

+
5CDS-intronENST00000296257ENST00000436004SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
5CDS-intronENST00000296257ENST00000436192SENP2chr3

185316812

+MSH5chr6

31726543

+
5CDS-intronENST00000296257ENST00000436192SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
5CDS-intronENST00000296257ENST00000436559SENP2chr3

185316812

+MSH5chr6

31726543

+
5CDS-intronENST00000296257ENST00000436559SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
5CDS-intronENST00000296257ENST00000439816SENP2chr3

185316812

+MSH5chr6

31726543

+
5CDS-intronENST00000296257ENST00000439816SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
5CDS-intronENST00000296257ENST00000441395SENP2chr3

185316812

+MSH5chr6

31726543

+
5CDS-intronENST00000296257ENST00000441395SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
5CDS-intronENST00000296257ENST00000441401SENP2chr3

185316812

+MSH5chr6

31726543

+
5CDS-intronENST00000296257ENST00000441401SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
5CDS-intronENST00000296257ENST00000443040SENP2chr3

185316812

+MSH5chr6

31726543

+
5CDS-intronENST00000296257ENST00000443040SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
5CDS-intronENST00000296257ENST00000448169SENP2chr3

185316812

+MSH5chr6

31726543

+
5CDS-intronENST00000296257ENST00000448169SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
5CDS-intronENST00000296257ENST00000448617SENP2chr3

185316812

+MSH5chr6

31726543

+
5CDS-intronENST00000296257ENST00000448617SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
5CDS-intronENST00000296257ENST00000456839SENP2chr3

185316812

+MSH5chr6

31726543

+
5CDS-intronENST00000296257ENST00000456839SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
5CDS-intronENST00000296257ENST00000457742SENP2chr3

185316812

+MSH5chr6

31726543

+
5CDS-intronENST00000296257ENST00000457742SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
5CDS-intronENST00000296257ENST00000457917SENP2chr3

185316812

+MSH5chr6

31726543

+
5CDS-intronENST00000296257ENST00000458144SENP2chr3

185316812

+MSH5chr6

31726543

+
5CDS-intronENST00000296257ENST00000458144SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
5CDS-intronENST00000296257ENST00000460275SENP2chr3

185316812

+MSH5chr6

31726543

+
5CDS-intronENST00000296257ENST00000460275SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
5CDS-intronENST00000296257ENST00000473342SENP2chr3

185316812

+MSH5chr6

31726543

+
5CDS-intronENST00000296257ENST00000473342SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
5CDS-intronENST00000296257ENST00000478326SENP2chr3

185316812

+MSH5chr6

31726543

+
5CDS-intronENST00000296257ENST00000478326SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
5CDS-intronENST00000296257ENST00000480915SENP2chr3

185316812

+MSH5chr6

31726543

+
5CDS-intronENST00000296257ENST00000480915SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
5CDS-intronENST00000296257ENST00000482280SENP2chr3

185316812

+MSH5chr6

31726543

+
5CDS-intronENST00000296257ENST00000482280SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
5CDS-intronENST00000296257ENST00000486924SENP2chr3

185316812

+MSH5chr6

31726543

+
5CDS-intronENST00000296257ENST00000486924SENP2chr3

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5CDS-intronENST00000296257ENST00000490125SENP2chr3

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5CDS-intronENST00000296257ENST00000497157SENP2chr3

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5CDS-intronENST00000296257ENST00000497157SENP2chr3

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5CDS-intronENST00000296257ENST00000534153SENP2chr3

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5CDS-intronENST00000296257ENST00000549604SENP2chr3

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5CDS-intronENST00000296257ENST00000549604SENP2chr3

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5CDS-intronENST00000296257ENST00000549746SENP2chr3

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5CDS-intronENST00000296257ENST00000549746SENP2chr3

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5CDS-intronENST00000296257ENST00000578225SENP2chr3

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5CDS-intronENST00000296257ENST00000578225SENP2chr3

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5CDS-intronENST00000545472ENST00000375703SENP2chr3

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5CDS-intronENST00000545472ENST00000375740SENP2chr3

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5CDS-intronENST00000545472ENST00000375742SENP2chr3

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5CDS-intronENST00000545472ENST00000375750SENP2chr3

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5CDS-intronENST00000545472ENST00000375755SENP2chr3

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5CDS-intronENST00000545472ENST00000395853SENP2chr3

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5CDS-intronENST00000545472ENST00000395853SENP2chr3

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5CDS-intronENST00000545472ENST00000414412SENP2chr3

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5CDS-intronENST00000545472ENST00000414412SENP2chr3

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5CDS-intronENST00000545472ENST00000416549SENP2chr3

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5CDS-intronENST00000545472ENST00000416549SENP2chr3

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5CDS-intronENST00000545472ENST00000419269SENP2chr3

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5CDS-intronENST00000545472ENST00000419269SENP2chr3

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5CDS-intronENST00000545472ENST00000427735SENP2chr3

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5CDS-intronENST00000545472ENST00000427735SENP2chr3

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5CDS-intronENST00000545472ENST00000430216SENP2chr3

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5CDS-intronENST00000545472ENST00000430216SENP2chr3

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5CDS-intronENST00000545472ENST00000431848SENP2chr3

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5CDS-intronENST00000545472ENST00000435700SENP2chr3

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5CDS-intronENST00000545472ENST00000435700SENP2chr3

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5CDS-intronENST00000545472ENST00000436004SENP2chr3

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5CDS-intronENST00000545472ENST00000436004SENP2chr3

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5CDS-intronENST00000545472ENST00000436192SENP2chr3

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5CDS-intronENST00000545472ENST00000436192SENP2chr3

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5CDS-intronENST00000545472ENST00000436559SENP2chr3

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5CDS-intronENST00000545472ENST00000436559SENP2chr3

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5CDS-intronENST00000545472ENST00000439816SENP2chr3

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5CDS-intronENST00000545472ENST00000439816SENP2chr3

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5CDS-intronENST00000545472ENST00000441395SENP2chr3

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5CDS-intronENST00000545472ENST00000441395SENP2chr3

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5CDS-intronENST00000545472ENST00000441401SENP2chr3

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5CDS-intronENST00000545472ENST00000441401SENP2chr3

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5CDS-intronENST00000545472ENST00000443040SENP2chr3

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5CDS-intronENST00000545472ENST00000443040SENP2chr3

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5CDS-intronENST00000545472ENST00000448169SENP2chr3

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5CDS-intronENST00000545472ENST00000448169SENP2chr3

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5CDS-intronENST00000545472ENST00000448617SENP2chr3

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5CDS-intronENST00000545472ENST00000448617SENP2chr3

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5CDS-intronENST00000545472ENST00000456839SENP2chr3

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5CDS-intronENST00000545472ENST00000456839SENP2chr3

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5CDS-intronENST00000545472ENST00000457742SENP2chr3

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5CDS-intronENST00000545472ENST00000457742SENP2chr3

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5CDS-intronENST00000545472ENST00000457917SENP2chr3

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5CDS-intronENST00000545472ENST00000458144SENP2chr3

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5CDS-intronENST00000545472ENST00000460275SENP2chr3

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5CDS-intronENST00000545472ENST00000460275SENP2chr3

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5CDS-intronENST00000545472ENST00000473342SENP2chr3

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5CDS-intronENST00000545472ENST00000473342SENP2chr3

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5CDS-intronENST00000545472ENST00000478326SENP2chr3

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5CDS-intronENST00000545472ENST00000478326SENP2chr3

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5CDS-intronENST00000545472ENST00000480915SENP2chr3

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5CDS-intronENST00000545472ENST00000480915SENP2chr3

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5CDS-intronENST00000545472ENST00000482280SENP2chr3

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5CDS-intronENST00000545472ENST00000482280SENP2chr3

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5CDS-intronENST00000545472ENST00000486924SENP2chr3

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5CDS-intronENST00000545472ENST00000486924SENP2chr3

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5CDS-intronENST00000545472ENST00000490125SENP2chr3

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5CDS-intronENST00000545472ENST00000534153SENP2chr3

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5CDS-intronENST00000545472ENST00000549604SENP2chr3

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5CDS-intronENST00000545472ENST00000549604SENP2chr3

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5CDS-intronENST00000545472ENST00000549746SENP2chr3

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5CDS-intronENST00000545472ENST00000549746SENP2chr3

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5CDS-intronENST00000545472ENST00000578225SENP2chr3

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5CDS-intronENST00000545472ENST00000578225SENP2chr3

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intron-3CDSENST00000427465ENST00000375703SENP2chr3

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intron-3CDSENST00000427465ENST00000375740SENP2chr3

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intron-3CDSENST00000427465ENST00000375742SENP2chr3

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intron-3CDSENST00000427465ENST00000375750SENP2chr3

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intron-3CDSENST00000427465ENST00000375755SENP2chr3

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intron-3CDSENST00000427465ENST00000431848SENP2chr3

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intron-3CDSENST00000427465ENST00000534153SENP2chr3

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intron-3UTRENST00000427465ENST00000457917SENP2chr3

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intron-3UTRENST00000427465ENST00000490125SENP2chr3

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intron-intronENST00000427465ENST00000375703SENP2chr3

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intron-intronENST00000427465ENST00000375740SENP2chr3

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intron-intronENST00000427465ENST00000375742SENP2chr3

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intron-intronENST00000427465ENST00000375750SENP2chr3

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intron-intronENST00000427465ENST00000375755SENP2chr3

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intron-intronENST00000427465ENST00000395853SENP2chr3

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intron-intronENST00000427465ENST00000395853SENP2chr3

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intron-intronENST00000427465ENST00000414412SENP2chr3

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intron-intronENST00000427465ENST00000414412SENP2chr3

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intron-intronENST00000427465ENST00000416549SENP2chr3

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intron-intronENST00000427465ENST00000416549SENP2chr3

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intron-intronENST00000427465ENST00000419269SENP2chr3

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intron-intronENST00000427465ENST00000419269SENP2chr3

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intron-intronENST00000427465ENST00000427735SENP2chr3

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intron-intronENST00000427465ENST00000427735SENP2chr3

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intron-intronENST00000427465ENST00000430216SENP2chr3

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intron-intronENST00000427465ENST00000430216SENP2chr3

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intron-intronENST00000427465ENST00000431848SENP2chr3

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intron-intronENST00000427465ENST00000435700SENP2chr3

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intron-intronENST00000427465ENST00000435700SENP2chr3

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intron-intronENST00000427465ENST00000436004SENP2chr3

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intron-intronENST00000427465ENST00000436004SENP2chr3

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intron-intronENST00000427465ENST00000436192SENP2chr3

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intron-intronENST00000427465ENST00000436192SENP2chr3

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intron-intronENST00000427465ENST00000436559SENP2chr3

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intron-intronENST00000427465ENST00000436559SENP2chr3

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intron-intronENST00000427465ENST00000439816SENP2chr3

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intron-intronENST00000427465ENST00000439816SENP2chr3

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intron-intronENST00000427465ENST00000441395SENP2chr3

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intron-intronENST00000427465ENST00000441395SENP2chr3

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intron-intronENST00000427465ENST00000441401SENP2chr3

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intron-intronENST00000427465ENST00000441401SENP2chr3

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intron-intronENST00000427465ENST00000443040SENP2chr3

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intron-intronENST00000427465ENST00000443040SENP2chr3

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intron-intronENST00000427465ENST00000448169SENP2chr3

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intron-intronENST00000427465ENST00000448169SENP2chr3

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intron-intronENST00000427465ENST00000448617SENP2chr3

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intron-intronENST00000427465ENST00000448617SENP2chr3

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intron-intronENST00000427465ENST00000456839SENP2chr3

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intron-intronENST00000427465ENST00000456839SENP2chr3

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intron-intronENST00000427465ENST00000457742SENP2chr3

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intron-intronENST00000427465ENST00000457742SENP2chr3

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intron-intronENST00000427465ENST00000457917SENP2chr3

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intron-intronENST00000427465ENST00000458144SENP2chr3

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intron-intronENST00000427465ENST00000458144SENP2chr3

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intron-intronENST00000427465ENST00000460275SENP2chr3

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intron-intronENST00000427465ENST00000460275SENP2chr3

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intron-intronENST00000427465ENST00000473342SENP2chr3

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intron-intronENST00000427465ENST00000473342SENP2chr3

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intron-intronENST00000427465ENST00000478326SENP2chr3

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intron-intronENST00000427465ENST00000478326SENP2chr3

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intron-intronENST00000427465ENST00000480915SENP2chr3

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intron-intronENST00000427465ENST00000480915SENP2chr3

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intron-intronENST00000427465ENST00000482280SENP2chr3

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intron-intronENST00000427465ENST00000482280SENP2chr3

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intron-intronENST00000427465ENST00000486924SENP2chr3

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intron-intronENST00000427465ENST00000486924SENP2chr3

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intron-intronENST00000427465ENST00000490125SENP2chr3

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intron-intronENST00000427465ENST00000497157SENP2chr3

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intron-intronENST00000427465ENST00000497157SENP2chr3

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intron-intronENST00000427465ENST00000534153SENP2chr3

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intron-intronENST00000427465ENST00000549604SENP2chr3

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intron-intronENST00000427465ENST00000549604SENP2chr3

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intron-intronENST00000427465ENST00000549746SENP2chr3

185316812

+MSH5chr6

31726543

+
intron-intronENST00000427465ENST00000549746SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+
intron-intronENST00000427465ENST00000578225SENP2chr3

185316812

+MSH5chr6

31726543

+
intron-intronENST00000427465ENST00000578225SENP2chr3

185316812

+MSH5chr6_qbl_hap6

3020185

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)
BP loci
(transcript)
Predicted start
(transcript)
Predicted stop
(transcript)
Seq length
(amino acids)
ENST00000545472SENP2chr3185316812+ENST00000375742MSH5chr631726543+1784356281644538
ENST00000545472SENP2chr3185316812+ENST00000375755MSH5chr631726543+1948356281644538
ENST00000545472SENP2chr3185316812+ENST00000375750MSH5chr631726543+1790356281644538
ENST00000545472SENP2chr3185316812+ENST00000534153MSH5chr631726543+3019356281644538
ENST00000545472SENP2chr3185316812+ENST00000375703MSH5chr631726543+1793356281647539
ENST00000545472SENP2chr3185316812+ENST00000375740MSH5chr631726543+1703356281557509
ENST00000545472SENP2chr3185316812+ENST00000431848MSH5chr631726543+1749356281644538
ENST00000296257SENP2chr3185316812+ENST00000375742MSH5chr631726543+202659891886625
ENST00000296257SENP2chr3185316812+ENST00000375755MSH5chr631726543+219059891886625
ENST00000296257SENP2chr3185316812+ENST00000375750MSH5chr631726543+203259891886625
ENST00000296257SENP2chr3185316812+ENST00000534153MSH5chr631726543+326159891886625
ENST00000296257SENP2chr3185316812+ENST00000375703MSH5chr631726543+203559891889626
ENST00000296257SENP2chr3185316812+ENST00000375740MSH5chr631726543+194559891799596
ENST00000296257SENP2chr3185316812+ENST00000431848MSH5chr631726543+199159891886625

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000545472ENST00000375742SENP2chr3185316812+MSH5chr631726543+0.0035731990.99642676
ENST00000545472ENST00000375755SENP2chr3185316812+MSH5chr631726543+0.0029975840.9970024
ENST00000545472ENST00000375750SENP2chr3185316812+MSH5chr631726543+0.0035581330.9964419
ENST00000545472ENST00000534153SENP2chr3185316812+MSH5chr631726543+0.0052658780.99473417
ENST00000545472ENST00000375703SENP2chr3185316812+MSH5chr631726543+0.003707690.9962923
ENST00000545472ENST00000375740SENP2chr3185316812+MSH5chr631726543+0.0027842410.99721575
ENST00000545472ENST00000431848SENP2chr3185316812+MSH5chr631726543+0.003872460.99612755
ENST00000296257ENST00000375742SENP2chr3185316812+MSH5chr631726543+0.0106756270.9893244
ENST00000296257ENST00000375755SENP2chr3185316812+MSH5chr631726543+0.0089183030.9910817
ENST00000296257ENST00000375750SENP2chr3185316812+MSH5chr631726543+0.0106992830.98930067
ENST00000296257ENST00000534153SENP2chr3185316812+MSH5chr631726543+0.0134437410.9865563
ENST00000296257ENST00000375703SENP2chr3185316812+MSH5chr631726543+0.0125036870.98749626
ENST00000296257ENST00000375740SENP2chr3185316812+MSH5chr631726543+0.0107291080.9892709
ENST00000296257ENST00000431848SENP2chr3185316812+MSH5chr631726543+0.0118674890.98813254

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Fusion Genomic Features for SENP2-MSH5


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
SENP2chr3185316812+MSH5chr6_qbl_hap63020184+4.30E-070.9999995
SENP2chr3185316812+MSH5chr631726542+2.53E-111
SENP2chr3185316812+MSH5chr6_qbl_hap63020184+4.30E-070.9999995
SENP2chr3185316812+MSH5chr631726542+2.53E-111

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for SENP2-MSH5


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr3:185316812/chr6:31726543)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.MSH5

O43196

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Involved in DNA mismatch repair and meiotic recombination processes. Facilitates crossovers between homologs during meiosis (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSENP2chr3:185316812chr6:31726543ENST00000296257+41728_31119590.0MotifNuclear localization signal
HgeneSENP2chr3:185316812chr6:31726543ENST00000296257+41746_51119590.0MotifNuclear localization signal
TgeneMSH5chr3:185316812chr6:31726543ENST000003757031325592_599405836.0Nucleotide bindingATP
TgeneMSH5chr3:185316812chr6:31726543ENST000003757401325592_599422823.0Nucleotide bindingATP
TgeneMSH5chr3:185316812chr6:31726543ENST000003757421325592_599422852.0Nucleotide bindingATP
TgeneMSH5chr3:185316812chr6:31726543ENST000003757501325592_599405835.0Nucleotide bindingATP
TgeneMSH5chr3:185316812chr6:31726543ENST000003757551325592_599405835.0Nucleotide bindingATP
TgeneMSH5chr3:185316812chr6:31726543ENST00000416549025592_5990835.0Nucleotide bindingATP
TgeneMSH5chr3:185316812chr6:31726543ENST00000419269025592_5990836.0Nucleotide bindingATP
TgeneMSH5chr3:185316812chr6:31726543ENST00000427735025592_5990835.0Nucleotide bindingATP
TgeneMSH5chr3:185316812chr6:31726543ENST00000435700025592_5990836.0Nucleotide bindingATP
TgeneMSH5chr3:185316812chr6:31726543ENST00000436192025592_5990836.0Nucleotide bindingATP
TgeneMSH5chr3:185316812chr6:31726543ENST00000441395025592_5990835.0Nucleotide bindingATP
TgeneMSH5chr3:185316812chr6:31726543ENST00000441401025592_5990835.0Nucleotide bindingATP
TgeneMSH5chr3:185316812chr6:31726543ENST00000448617025592_5990823.0Nucleotide bindingATP
TgeneMSH5chr3:185316812chr6:31726543ENST00000456839025592_5990835.0Nucleotide bindingATP
TgeneMSH5chr3:185316812chr6:31726543ENST00000457742025592_5990835.0Nucleotide bindingATP
TgeneMSH5chr3:185316812chr6:31726543ENST00000497157029592_5990961.6666666666666Nucleotide bindingATP
TgeneMSH5chr3:185316812chr6:31726543ENST000005341531329592_599422961.6666666666666Nucleotide bindingATP
TgeneMSH5chr3:185316812chr6:31726543ENST00000578225029592_5990961.6666666666666Nucleotide bindingATP

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSENP2chr3:185316812chr6:31726543ENST00000296257+417317_332119590.0MotifNote=Nuclear export signal
HgeneSENP2chr3:185316812chr6:31726543ENST00000296257+417396_560119590.0RegionNote=Protease


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Fusion Gene Sequence for SENP2-MSH5


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>80382_80382_1_SENP2-MSH5_SENP2_chr3_185316812_ENST00000296257_MSH5_chr6_31726543_ENST00000375703_length(transcript)=2035nt_BP=598nt
GTGCGCAGATTGAGAATGGAGCTTTCCGGTCGGGCGGGAGGAGGTGACGTCAGGAGTGGTGGCGGGCGGGGGCCTCTGGTAGCCCTGGGG
ACGCTGTATCTGTGGGCTCTTGAATCGCGTCACAAATCAGCGACCGAACTCTGGCGGTGGTGGTTAAGACGGCGAAGGCGGCAGCGGCGG
CGACAGCTCTGGGGTTTGCGTCTCGGGGTGTGTCGGCCGCCGCTGCTGCTTGGGCCTGGTATGTACAGATGGCTGGTTAGGATTCTCGGC
ACCATTTTCCGTTTCTGCGACCGGTCGGTGCCCCCTGCCCGGGCCCTCCTGAAGAGGCGGCGCTCAGACAGCACTCTGTTTTCTACAGTG
GACACTGATGAAATACCAGCCAAAAGACCAAGATTAGATTGCTTTATTCACCAAGTGAAAAACAGTCTCTACAATGCTGCCAGCTTATTT
GGATTCCCATTCCAGCTGACCACAAAGCCCATGGTAACTTCTGCTTGTAATGGAACACGGAATGTGGCCCCTTCAGGAGAGGTATTTTCG
AACTCTTCATCTTGTGAACTGACAGGTTCTGGATCCTGGAACAACATGCTGAAACTGGAAAAGCGAAGACTGATGGGACTTCCCAGTTTC
CTTACTGAGGTTGCCCGCAAGGAGCTGGAGAATCTGGACTCCCGTATTCCTTCATGCAGTGTCATCTACATCCCTCTGATTGGCTTCCTT
CTTTCTATTCCCCGCCTGCCTTCCATGGTAGAGGCCAGTGACTTTGAGATTAATGGACTGGACTTCATGTTTCTCTCAGAGGAGAAGCTG
CACTATCGTAGTGCCCGAACCAAGGAGCTGGATGCATTGCTGGGGGACCTGCACTGCGAGATCCGGGACCAGGAGACGCTGCTGATGTAC
CAGCTACAGTGCCAGGTGCTGGCACGAGCAGCTGTCTTAACCCGAGTATTGGACCTTGCCTCCCGCCTGGACGTCCTGCTGGCTCTTGCC
AGTGCTGCCCGGGACTATGGCTACTCAAGGCCGCGTTACTCCCCACAAGTCCTTGGGGTACGAATCCAGAATGGCAGACATCCTCTGATG
GAACTCTGTGCCCGAACCTTTGTGCCCAACTCCACAGAATGTGGTGGGGACAAAGGGAGGGTCAAAGTCATCACTGGACCCAACTCATCA
GGGAAGAGCATATACCTCAAACAGGTAGGCTTGATCACATTCATGGCCCTGGTAGGCAGCTTTGTGCCAGCAGAGGAGGCCGAAATTGGG
GCAGTAGACGCCATCTTCACACGAATTCATAGCTGCGAATCCATCTCCCTTGGCCTCTCCACCTTCATGATCGACCTCAACCAGCAGGTG
GCGAAAGCAGTGAACAATGCCACTGCACAGTCGCTGGTCCTTATTGATGAATTTGGAAAGGGAACCAACACGGTGGATGGGCTCGCGCTT
CTGGCCGCTGTGCTCCGACACTGGCTGGCACGTGGACCCACATGCCCCCACATCTTTGTGGCCACCAACTTTCTGAGCCTTGTTCAGCTA
CAACTGCTGCCACAAGGGCCCCTGGTGCAGTATTTGACCATGGAGACCTGTGAGGATGGCAACGATCTTGTCTTCTTCTATCAGGTTTGC
GAAGGTGTTGCGAAGGCCAGCCATGCCTCCCACACAGCTGCCCAGGCTGGGCTTCCTGACAAGCTTGTGGCTCGTGGCAAGGAGGTCTCA
GACTTGATCCGCAGTGGAAAACCCATCAAGCCTGTCAAGGATTTGCTAAAGAAGAACCAAATGGAAAATTGCCAGACATTAGTGGATAAG
TTTATGAAACTGGATTTGGAAGATCCTAACCTGGACTTGAACGTTTTCATGAGCCAGGAAGTGCTGCCTGCTGCCACCAGCATCCTCTGA
GAGTCCTTCCAGTGTCCTCCCCAGCCTCCTGAGACTCCGGTGGGCTGCCATGCCCTCTTTGTTTCCTTATCTCCCTCAGACGCAGAGTTT

>80382_80382_1_SENP2-MSH5_SENP2_chr3_185316812_ENST00000296257_MSH5_chr6_31726543_ENST00000375703_length(amino acids)=626AA_BP=196
MRMELSGRAGGGDVRSGGGRGPLVALGTLYLWALESRHKSATELWRWWLRRRRRQRRRQLWGLRLGVCRPPLLLGPGMYRWLVRILGTIF
RFCDRSVPPARALLKRRRSDSTLFSTVDTDEIPAKRPRLDCFIHQVKNSLYNAASLFGFPFQLTTKPMVTSACNGTRNVAPSGEVFSNSS
SCELTGSGSWNNMLKLEKRRLMGLPSFLTEVARKELENLDSRIPSCSVIYIPLIGFLLSIPRLPSMVEASDFEINGLDFMFLSEEKLHYR
SARTKELDALLGDLHCEIRDQETLLMYQLQCQVLARAAVLTRVLDLASRLDVLLALASAARDYGYSRPRYSPQVLGVRIQNGRHPLMELC
ARTFVPNSTECGGDKGRVKVITGPNSSGKSIYLKQVGLITFMALVGSFVPAEEAEIGAVDAIFTRIHSCESISLGLSTFMIDLNQQVAKA
VNNATAQSLVLIDEFGKGTNTVDGLALLAAVLRHWLARGPTCPHIFVATNFLSLVQLQLLPQGPLVQYLTMETCEDGNDLVFFYQVCEGV

--------------------------------------------------------------
>80382_80382_2_SENP2-MSH5_SENP2_chr3_185316812_ENST00000296257_MSH5_chr6_31726543_ENST00000375740_length(transcript)=1945nt_BP=598nt
GTGCGCAGATTGAGAATGGAGCTTTCCGGTCGGGCGGGAGGAGGTGACGTCAGGAGTGGTGGCGGGCGGGGGCCTCTGGTAGCCCTGGGG
ACGCTGTATCTGTGGGCTCTTGAATCGCGTCACAAATCAGCGACCGAACTCTGGCGGTGGTGGTTAAGACGGCGAAGGCGGCAGCGGCGG
CGACAGCTCTGGGGTTTGCGTCTCGGGGTGTGTCGGCCGCCGCTGCTGCTTGGGCCTGGTATGTACAGATGGCTGGTTAGGATTCTCGGC
ACCATTTTCCGTTTCTGCGACCGGTCGGTGCCCCCTGCCCGGGCCCTCCTGAAGAGGCGGCGCTCAGACAGCACTCTGTTTTCTACAGTG
GACACTGATGAAATACCAGCCAAAAGACCAAGATTAGATTGCTTTATTCACCAAGTGAAAAACAGTCTCTACAATGCTGCCAGCTTATTT
GGATTCCCATTCCAGCTGACCACAAAGCCCATGGTAACTTCTGCTTGTAATGGAACACGGAATGTGGCCCCTTCAGGAGAGGTATTTTCG
AACTCTTCATCTTGTGAACTGACAGGTTCTGGATCCTGGAACAACATGCTGAAACTGGAAAAGCGAAGACTGATGGGACTTCCCAGTTTC
CTTACTGAGGTTGCCCGCAAGGAGCTGGAGAATCTGGACTCCCGTATTCCTTCATGCAGTGTCATCTACATCCCTCTGATTGGCTTCCTT
CTTTCTATTCCCCGCCTGCCTTCCATGGTAGAGGCCAGTGACTTTGAGATTAATGGACTGGACTTCATGTTTCTCTCAGAGGAGAAGCTG
CACTATCGTAGTGCCCGAACCAAGGAGCTGGATGCATTGCTGGGGGACCTGCACTGCGAGATCCGGGACCAGGAGACGCTGCTGATGTAC
CAGCTACAGTGCCAGGTGCTGGCACGAGCAGCTGTCTTAACCCGAGTATTGGACCTTGCCTCCCGCCTGGACGTCCTGCTGGCTCTTGCC
AGTGCTGCCCGGGACTATGGCTACTCAAGGCCGCGTTACTCCCCACAAGTCCTTGGGGTACGAATCCAGAATGGCAGACATCCTCTGATG
GAACTCTGTGCCCGAACCTTTGTGCCCAACTCCACAGAATGTGGTGGGGACAAAGGGAGGGTCAAAGTCATCACTGGACCCAACTCATCA
GGGAAGAGCATATACCTCAAACAGGTAGGCTTGATCACATTCATGGCCCTGGTAGGCAGCTTTGTGCCAGCAGAGGAGGCCGAAATTGGG
GCAGTAGACGCCATCTTCACACGAATTCATAGCTGCGAATCCATCTCCCTTGGCCTCTCCACCTTCATGATCGACCTCAACCAGCAGGTG
GCGAAAGCAGTGAACAATGCCACTGCACAGTCGCTGGTCCTTATTGATGAATTTGGAAAGGGAACCAACACGGTGGATGGGCTCGCGCTT
CTGGCCGCTGTGCTCCGACACTGGCTGGCACGTGGACCCACATGCCCCCACATCTTTGTGGCCACCAACTTTCTGAGCCTTGTTCAGCTA
CAACTGCTGCCACAAGGGCCCCTGGTGCAGTATTTGACCATGGAGACCTGTGAGGATGGCAACGATCTTGTCTTCTTCTATCAGGTCTCA
GACTTGATCCGCAGTGGAAAACCCATCAAGCCTGTCAAGGATTTGCTAAAGAAGAACCAAATGGAAAATTGCCAGACATTAGTGGATAAG
TTTATGAAACTGGATTTGGAAGATCCTAACCTGGACTTGAACGTTTTCATGAGCCAGGAAGTGCTGCCTGCTGCCACCAGCATCCTCTGA
GAGTCCTTCCAGTGTCCTCCCCAGCCTCCTGAGACTCCGGTGGGCTGCCATGCCCTCTTTGTTTCCTTATCTCCCTCAGACGCAGAGTTT

>80382_80382_2_SENP2-MSH5_SENP2_chr3_185316812_ENST00000296257_MSH5_chr6_31726543_ENST00000375740_length(amino acids)=596AA_BP=196
MRMELSGRAGGGDVRSGGGRGPLVALGTLYLWALESRHKSATELWRWWLRRRRRQRRRQLWGLRLGVCRPPLLLGPGMYRWLVRILGTIF
RFCDRSVPPARALLKRRRSDSTLFSTVDTDEIPAKRPRLDCFIHQVKNSLYNAASLFGFPFQLTTKPMVTSACNGTRNVAPSGEVFSNSS
SCELTGSGSWNNMLKLEKRRLMGLPSFLTEVARKELENLDSRIPSCSVIYIPLIGFLLSIPRLPSMVEASDFEINGLDFMFLSEEKLHYR
SARTKELDALLGDLHCEIRDQETLLMYQLQCQVLARAAVLTRVLDLASRLDVLLALASAARDYGYSRPRYSPQVLGVRIQNGRHPLMELC
ARTFVPNSTECGGDKGRVKVITGPNSSGKSIYLKQVGLITFMALVGSFVPAEEAEIGAVDAIFTRIHSCESISLGLSTFMIDLNQQVAKA
VNNATAQSLVLIDEFGKGTNTVDGLALLAAVLRHWLARGPTCPHIFVATNFLSLVQLQLLPQGPLVQYLTMETCEDGNDLVFFYQVSDLI

--------------------------------------------------------------
>80382_80382_3_SENP2-MSH5_SENP2_chr3_185316812_ENST00000296257_MSH5_chr6_31726543_ENST00000375742_length(transcript)=2026nt_BP=598nt
GTGCGCAGATTGAGAATGGAGCTTTCCGGTCGGGCGGGAGGAGGTGACGTCAGGAGTGGTGGCGGGCGGGGGCCTCTGGTAGCCCTGGGG
ACGCTGTATCTGTGGGCTCTTGAATCGCGTCACAAATCAGCGACCGAACTCTGGCGGTGGTGGTTAAGACGGCGAAGGCGGCAGCGGCGG
CGACAGCTCTGGGGTTTGCGTCTCGGGGTGTGTCGGCCGCCGCTGCTGCTTGGGCCTGGTATGTACAGATGGCTGGTTAGGATTCTCGGC
ACCATTTTCCGTTTCTGCGACCGGTCGGTGCCCCCTGCCCGGGCCCTCCTGAAGAGGCGGCGCTCAGACAGCACTCTGTTTTCTACAGTG
GACACTGATGAAATACCAGCCAAAAGACCAAGATTAGATTGCTTTATTCACCAAGTGAAAAACAGTCTCTACAATGCTGCCAGCTTATTT
GGATTCCCATTCCAGCTGACCACAAAGCCCATGGTAACTTCTGCTTGTAATGGAACACGGAATGTGGCCCCTTCAGGAGAGGTATTTTCG
AACTCTTCATCTTGTGAACTGACAGGTTCTGGATCCTGGAACAACATGCTGAAACTGGAAAAGCGAAGACTGATGGGACTTCCCAGTTTC
CTTACTGAGGTTGCCCGCAAGGAGCTGGAGAATCTGGACTCCCGTATTCCTTCATGCAGTGTCATCTACATCCCTCTGATTGGCTTCCTT
CTTTCTATTCCCCGCCTGCCTTCCATGGTAGAGGCCAGTGACTTTGAGATTAATGGACTGGACTTCATGTTTCTCTCAGAGGAGAAGCTG
CACTATCGTAGTGCCCGAACCAAGGAGCTGGATGCATTGCTGGGGGACCTGCACTGCGAGATCCGGGACCAGGAGACGCTGCTGATGTAC
CAGCTACAGTGCCAGGTGCTGGCACGAGCAGCTGTCTTAACCCGAGTATTGGACCTTGCCTCCCGCCTGGACGTCCTGCTGGCTCTTGCC
AGTGCTGCCCGGGACTATGGCTACTCAAGGCCGCGTTACTCCCCACAAGTCCTTGGGGTACGAATCCAGAATGGCAGACATCCTCTGATG
GAACTCTGTGCCCGAACCTTTGTGCCCAACTCCACAGAATGTGGTGGGGACAAAGGGAGGGTCAAAGTCATCACTGGACCCAACTCATCA
GGGAAGAGCATATACCTCAAACAGGTAGGCTTGATCACATTCATGGCCCTGGTAGGCAGCTTTGTGCCAGCAGAGGAGGCCGAAATTGGG
GCAGTAGACGCCATCTTCACACGAATTCATAGCTGCGAATCCATCTCCCTTGGCCTCTCCACCTTCATGATCGACCTCAACCAGGTGGCG
AAAGCAGTGAACAATGCCACTGCACAGTCGCTGGTCCTTATTGATGAATTTGGAAAGGGAACCAACACGGTGGATGGGCTCGCGCTTCTG
GCCGCTGTGCTCCGACACTGGCTGGCACGTGGACCCACATGCCCCCACATCTTTGTGGCCACCAACTTTCTGAGCCTTGTTCAGCTACAA
CTGCTGCCACAAGGGCCCCTGGTGCAGTATTTGACCATGGAGACCTGTGAGGATGGCAACGATCTTGTCTTCTTCTATCAGGTTTGCGAA
GGTGTTGCGAAGGCCAGCCATGCCTCCCACACAGCTGCCCAGGCTGGGCTTCCTGACAAGCTTGTGGCTCGTGGCAAGGAGGTCTCAGAC
TTGATCCGCAGTGGAAAACCCATCAAGCCTGTCAAGGATTTGCTAAAGAAGAACCAAATGGAAAATTGCCAGACATTAGTGGATAAGTTT
ATGAAACTGGATTTGGAAGATCCTAACCTGGACTTGAACGTTTTCATGAGCCAGGAAGTGCTGCCTGCTGCCACCAGCATCCTCTGAGAG
TCCTTCCAGTGTCCTCCCCAGCCTCCTGAGACTCCGGTGGGCTGCCATGCCCTCTTTGTTTCCTTATCTCCCTCAGACGCAGAGTTTTTA

>80382_80382_3_SENP2-MSH5_SENP2_chr3_185316812_ENST00000296257_MSH5_chr6_31726543_ENST00000375742_length(amino acids)=625AA_BP=196
MRMELSGRAGGGDVRSGGGRGPLVALGTLYLWALESRHKSATELWRWWLRRRRRQRRRQLWGLRLGVCRPPLLLGPGMYRWLVRILGTIF
RFCDRSVPPARALLKRRRSDSTLFSTVDTDEIPAKRPRLDCFIHQVKNSLYNAASLFGFPFQLTTKPMVTSACNGTRNVAPSGEVFSNSS
SCELTGSGSWNNMLKLEKRRLMGLPSFLTEVARKELENLDSRIPSCSVIYIPLIGFLLSIPRLPSMVEASDFEINGLDFMFLSEEKLHYR
SARTKELDALLGDLHCEIRDQETLLMYQLQCQVLARAAVLTRVLDLASRLDVLLALASAARDYGYSRPRYSPQVLGVRIQNGRHPLMELC
ARTFVPNSTECGGDKGRVKVITGPNSSGKSIYLKQVGLITFMALVGSFVPAEEAEIGAVDAIFTRIHSCESISLGLSTFMIDLNQVAKAV
NNATAQSLVLIDEFGKGTNTVDGLALLAAVLRHWLARGPTCPHIFVATNFLSLVQLQLLPQGPLVQYLTMETCEDGNDLVFFYQVCEGVA

--------------------------------------------------------------
>80382_80382_4_SENP2-MSH5_SENP2_chr3_185316812_ENST00000296257_MSH5_chr6_31726543_ENST00000375750_length(transcript)=2032nt_BP=598nt
GTGCGCAGATTGAGAATGGAGCTTTCCGGTCGGGCGGGAGGAGGTGACGTCAGGAGTGGTGGCGGGCGGGGGCCTCTGGTAGCCCTGGGG
ACGCTGTATCTGTGGGCTCTTGAATCGCGTCACAAATCAGCGACCGAACTCTGGCGGTGGTGGTTAAGACGGCGAAGGCGGCAGCGGCGG
CGACAGCTCTGGGGTTTGCGTCTCGGGGTGTGTCGGCCGCCGCTGCTGCTTGGGCCTGGTATGTACAGATGGCTGGTTAGGATTCTCGGC
ACCATTTTCCGTTTCTGCGACCGGTCGGTGCCCCCTGCCCGGGCCCTCCTGAAGAGGCGGCGCTCAGACAGCACTCTGTTTTCTACAGTG
GACACTGATGAAATACCAGCCAAAAGACCAAGATTAGATTGCTTTATTCACCAAGTGAAAAACAGTCTCTACAATGCTGCCAGCTTATTT
GGATTCCCATTCCAGCTGACCACAAAGCCCATGGTAACTTCTGCTTGTAATGGAACACGGAATGTGGCCCCTTCAGGAGAGGTATTTTCG
AACTCTTCATCTTGTGAACTGACAGGTTCTGGATCCTGGAACAACATGCTGAAACTGGAAAAGCGAAGACTGATGGGACTTCCCAGTTTC
CTTACTGAGGTTGCCCGCAAGGAGCTGGAGAATCTGGACTCCCGTATTCCTTCATGCAGTGTCATCTACATCCCTCTGATTGGCTTCCTT
CTTTCTATTCCCCGCCTGCCTTCCATGGTAGAGGCCAGTGACTTTGAGATTAATGGACTGGACTTCATGTTTCTCTCAGAGGAGAAGCTG
CACTATCGTAGTGCCCGAACCAAGGAGCTGGATGCATTGCTGGGGGACCTGCACTGCGAGATCCGGGACCAGGAGACGCTGCTGATGTAC
CAGCTACAGTGCCAGGTGCTGGCACGAGCAGCTGTCTTAACCCGAGTATTGGACCTTGCCTCCCGCCTGGACGTCCTGCTGGCTCTTGCC
AGTGCTGCCCGGGACTATGGCTACTCAAGGCCGCGTTACTCCCCACAAGTCCTTGGGGTACGAATCCAGAATGGCAGACATCCTCTGATG
GAACTCTGTGCCCGAACCTTTGTGCCCAACTCCACAGAATGTGGTGGGGACAAAGGGAGGGTCAAAGTCATCACTGGACCCAACTCATCA
GGGAAGAGCATATACCTCAAACAGGTAGGCTTGATCACATTCATGGCCCTGGTAGGCAGCTTTGTGCCAGCAGAGGAGGCCGAAATTGGG
GCAGTAGACGCCATCTTCACACGAATTCATAGCTGCGAATCCATCTCCCTTGGCCTCTCCACCTTCATGATCGACCTCAACCAGGTGGCG
AAAGCAGTGAACAATGCCACTGCACAGTCGCTGGTCCTTATTGATGAATTTGGAAAGGGAACCAACACGGTGGATGGGCTCGCGCTTCTG
GCCGCTGTGCTCCGACACTGGCTGGCACGTGGACCCACATGCCCCCACATCTTTGTGGCCACCAACTTTCTGAGCCTTGTTCAGCTACAA
CTGCTGCCACAAGGGCCCCTGGTGCAGTATTTGACCATGGAGACCTGTGAGGATGGCAACGATCTTGTCTTCTTCTATCAGGTTTGCGAA
GGTGTTGCGAAGGCCAGCCATGCCTCCCACACAGCTGCCCAGGCTGGGCTTCCTGACAAGCTTGTGGCTCGTGGCAAGGAGGTCTCAGAC
TTGATCCGCAGTGGAAAACCCATCAAGCCTGTCAAGGATTTGCTAAAGAAGAACCAAATGGAAAATTGCCAGACATTAGTGGATAAGTTT
ATGAAACTGGATTTGGAAGATCCTAACCTGGACTTGAACGTTTTCATGAGCCAGGAAGTGCTGCCTGCTGCCACCAGCATCCTCTGAGAG
TCCTTCCAGTGTCCTCCCCAGCCTCCTGAGACTCCGGTGGGCTGCCATGCCCTCTTTGTTTCCTTATCTCCCTCAGACGCAGAGTTTTTA

>80382_80382_4_SENP2-MSH5_SENP2_chr3_185316812_ENST00000296257_MSH5_chr6_31726543_ENST00000375750_length(amino acids)=625AA_BP=196
MRMELSGRAGGGDVRSGGGRGPLVALGTLYLWALESRHKSATELWRWWLRRRRRQRRRQLWGLRLGVCRPPLLLGPGMYRWLVRILGTIF
RFCDRSVPPARALLKRRRSDSTLFSTVDTDEIPAKRPRLDCFIHQVKNSLYNAASLFGFPFQLTTKPMVTSACNGTRNVAPSGEVFSNSS
SCELTGSGSWNNMLKLEKRRLMGLPSFLTEVARKELENLDSRIPSCSVIYIPLIGFLLSIPRLPSMVEASDFEINGLDFMFLSEEKLHYR
SARTKELDALLGDLHCEIRDQETLLMYQLQCQVLARAAVLTRVLDLASRLDVLLALASAARDYGYSRPRYSPQVLGVRIQNGRHPLMELC
ARTFVPNSTECGGDKGRVKVITGPNSSGKSIYLKQVGLITFMALVGSFVPAEEAEIGAVDAIFTRIHSCESISLGLSTFMIDLNQVAKAV
NNATAQSLVLIDEFGKGTNTVDGLALLAAVLRHWLARGPTCPHIFVATNFLSLVQLQLLPQGPLVQYLTMETCEDGNDLVFFYQVCEGVA

--------------------------------------------------------------
>80382_80382_5_SENP2-MSH5_SENP2_chr3_185316812_ENST00000296257_MSH5_chr6_31726543_ENST00000375755_length(transcript)=2190nt_BP=598nt
GTGCGCAGATTGAGAATGGAGCTTTCCGGTCGGGCGGGAGGAGGTGACGTCAGGAGTGGTGGCGGGCGGGGGCCTCTGGTAGCCCTGGGG
ACGCTGTATCTGTGGGCTCTTGAATCGCGTCACAAATCAGCGACCGAACTCTGGCGGTGGTGGTTAAGACGGCGAAGGCGGCAGCGGCGG
CGACAGCTCTGGGGTTTGCGTCTCGGGGTGTGTCGGCCGCCGCTGCTGCTTGGGCCTGGTATGTACAGATGGCTGGTTAGGATTCTCGGC
ACCATTTTCCGTTTCTGCGACCGGTCGGTGCCCCCTGCCCGGGCCCTCCTGAAGAGGCGGCGCTCAGACAGCACTCTGTTTTCTACAGTG
GACACTGATGAAATACCAGCCAAAAGACCAAGATTAGATTGCTTTATTCACCAAGTGAAAAACAGTCTCTACAATGCTGCCAGCTTATTT
GGATTCCCATTCCAGCTGACCACAAAGCCCATGGTAACTTCTGCTTGTAATGGAACACGGAATGTGGCCCCTTCAGGAGAGGTATTTTCG
AACTCTTCATCTTGTGAACTGACAGGTTCTGGATCCTGGAACAACATGCTGAAACTGGAAAAGCGAAGACTGATGGGACTTCCCAGTTTC
CTTACTGAGGTTGCCCGCAAGGAGCTGGAGAATCTGGACTCCCGTATTCCTTCATGCAGTGTCATCTACATCCCTCTGATTGGCTTCCTT
CTTTCTATTCCCCGCCTGCCTTCCATGGTAGAGGCCAGTGACTTTGAGATTAATGGACTGGACTTCATGTTTCTCTCAGAGGAGAAGCTG
CACTATCGTAGTGCCCGAACCAAGGAGCTGGATGCATTGCTGGGGGACCTGCACTGCGAGATCCGGGACCAGGAGACGCTGCTGATGTAC
CAGCTACAGTGCCAGGTGCTGGCACGAGCAGCTGTCTTAACCCGAGTATTGGACCTTGCCTCCCGCCTGGACGTCCTGCTGGCTCTTGCC
AGTGCTGCCCGGGACTATGGCTACTCAAGGCCGCGTTACTCCCCACAAGTCCTTGGGGTACGAATCCAGAATGGCAGACATCCTCTGATG
GAACTCTGTGCCCGAACCTTTGTGCCCAACTCCACAGAATGTGGTGGGGACAAAGGGAGGGTCAAAGTCATCACTGGACCCAACTCATCA
GGGAAGAGCATATACCTCAAACAGGTAGGCTTGATCACATTCATGGCCCTGGTAGGCAGCTTTGTGCCAGCAGAGGAGGCCGAAATTGGG
GCAGTAGACGCCATCTTCACACGAATTCATAGCTGCGAATCCATCTCCCTTGGCCTCTCCACCTTCATGATCGACCTCAACCAGGTGGCG
AAAGCAGTGAACAATGCCACTGCACAGTCGCTGGTCCTTATTGATGAATTTGGAAAGGGAACCAACACGGTGGATGGGCTCGCGCTTCTG
GCCGCTGTGCTCCGACACTGGCTGGCACGTGGACCCACATGCCCCCACATCTTTGTGGCCACCAACTTTCTGAGCCTTGTTCAGCTACAA
CTGCTGCCACAAGGGCCCCTGGTGCAGTATTTGACCATGGAGACCTGTGAGGATGGCAACGATCTTGTCTTCTTCTATCAGGTTTGCGAA
GGTGTTGCGAAGGCCAGCCATGCCTCCCACACAGCTGCCCAGGCTGGGCTTCCTGACAAGCTTGTGGCTCGTGGCAAGGAGGTCTCAGAC
TTGATCCGCAGTGGAAAACCCATCAAGCCTGTCAAGGATTTGCTAAAGAAGAACCAAATGGAAAATTGCCAGACATTAGTGGATAAGTTT
ATGAAACTGGATTTGGAAGATCCTAACCTGGACTTGAACGTTTTCATGAGCCAGGAAGTGCTGCCTGCTGCCACCAGCATCCTCTGAGAG
TCCTTCCAGTGTCCTCCCCAGCCTCCTGAGACTCCGGTGGGCTGCCATGCCCTCTTTGTTTCCTTATCTCCCTCAGACGCAGAGTTTTTA
GTTTCTCTAGAAATTTTGTTTCATATTAGGAATAAAGTTTATTTTGAAGAAAGATATTGTTTCTTTAGTCTCAAAACAAGAGACTAGGAA
AGATCCAAAACACAGAGCAGGAGTCCACAGGGGAACCTGCCCTGCCTCAGTAAAAATACAGTGTTGTTGCTGTAGGAAGACTCCCGGATT

>80382_80382_5_SENP2-MSH5_SENP2_chr3_185316812_ENST00000296257_MSH5_chr6_31726543_ENST00000375755_length(amino acids)=625AA_BP=196
MRMELSGRAGGGDVRSGGGRGPLVALGTLYLWALESRHKSATELWRWWLRRRRRQRRRQLWGLRLGVCRPPLLLGPGMYRWLVRILGTIF
RFCDRSVPPARALLKRRRSDSTLFSTVDTDEIPAKRPRLDCFIHQVKNSLYNAASLFGFPFQLTTKPMVTSACNGTRNVAPSGEVFSNSS
SCELTGSGSWNNMLKLEKRRLMGLPSFLTEVARKELENLDSRIPSCSVIYIPLIGFLLSIPRLPSMVEASDFEINGLDFMFLSEEKLHYR
SARTKELDALLGDLHCEIRDQETLLMYQLQCQVLARAAVLTRVLDLASRLDVLLALASAARDYGYSRPRYSPQVLGVRIQNGRHPLMELC
ARTFVPNSTECGGDKGRVKVITGPNSSGKSIYLKQVGLITFMALVGSFVPAEEAEIGAVDAIFTRIHSCESISLGLSTFMIDLNQVAKAV
NNATAQSLVLIDEFGKGTNTVDGLALLAAVLRHWLARGPTCPHIFVATNFLSLVQLQLLPQGPLVQYLTMETCEDGNDLVFFYQVCEGVA

--------------------------------------------------------------
>80382_80382_6_SENP2-MSH5_SENP2_chr3_185316812_ENST00000296257_MSH5_chr6_31726543_ENST00000431848_length(transcript)=1991nt_BP=598nt
GTGCGCAGATTGAGAATGGAGCTTTCCGGTCGGGCGGGAGGAGGTGACGTCAGGAGTGGTGGCGGGCGGGGGCCTCTGGTAGCCCTGGGG
ACGCTGTATCTGTGGGCTCTTGAATCGCGTCACAAATCAGCGACCGAACTCTGGCGGTGGTGGTTAAGACGGCGAAGGCGGCAGCGGCGG
CGACAGCTCTGGGGTTTGCGTCTCGGGGTGTGTCGGCCGCCGCTGCTGCTTGGGCCTGGTATGTACAGATGGCTGGTTAGGATTCTCGGC
ACCATTTTCCGTTTCTGCGACCGGTCGGTGCCCCCTGCCCGGGCCCTCCTGAAGAGGCGGCGCTCAGACAGCACTCTGTTTTCTACAGTG
GACACTGATGAAATACCAGCCAAAAGACCAAGATTAGATTGCTTTATTCACCAAGTGAAAAACAGTCTCTACAATGCTGCCAGCTTATTT
GGATTCCCATTCCAGCTGACCACAAAGCCCATGGTAACTTCTGCTTGTAATGGAACACGGAATGTGGCCCCTTCAGGAGAGGTATTTTCG
AACTCTTCATCTTGTGAACTGACAGGTTCTGGATCCTGGAACAACATGCTGAAACTGGAAAAGCGAAGACTGATGGGACTTCCCAGTTTC
CTTACTGAGGTTGCCCGCAAGGAGCTGGAGAATCTGGACTCCCGTATTCCTTCATGCAGTGTCATCTACATCCCTCTGATTGGCTTCCTT
CTTTCTATTCCCCGCCTGCCTTCCATGGTAGAGGCCAGTGACTTTGAGATTAATGGACTGGACTTCATGTTTCTCTCAGAGGAGAAGCTG
CACTATCGTAGTGCCCGAACCAAGGAGCTGGATGCATTGCTGGGGGACCTGCACTGCGAGATCCGGGACCAGGAGACGCTGCTGATGTAC
CAGCTACAGTGCCAGGTGCTGGCACGAGCAGCTGTCTTAACCCGAGTATTGGACCTTGCCTCCCGCCTGGACGTCCTGCTGGCTCTTGCC
AGTGCTGCCCGGGACTATGGCTACTCAAGGCCGCGTTACTCCCCACAAGTCCTTGGGGTACGAATCCAGAATGGCAGACATCCTCTGATG
GAACTCTGTGCCCGAACCTTTGTGCCCAACTCCACAGAATGTGGTGGGGACAAAGGGAGGGTCAAAGTCATCACTGGACCCAACTCATCA
GGGAAGAGCATATACCTCAAACAGGTAGGCTTGATCACATTCATGGCCCTGGTAGGCAGCTTTGTGCCAGCAGAGGAGGCCGAAATTGGG
GCAGTAGACGCCATCTTCACACGAATTCATAGCTGCGAATCCATCTCCCTTGGCCTCTCCACCTTCATGATCGACCTCAACCAGGTGGCG
AAAGCAGTGAACAATGCCACTGCACAGTCGCTGGTCCTTATTGATGAATTTGGAAAGGGAACCAACACGGTGGATGGGCTCGCGCTTCTG
GCCGCTGTGCTCCGACACTGGCTGGCACGTGGACCCACATGCCCCCACATCTTTGTGGCCACCAACTTTCTGAGCCTTGTTCAGCTACAA
CTGCTGCCACAAGGGCCCCTGGTGCAGTATTTGACCATGGAGACCTGTGAGGATGGCAACGATCTTGTCTTCTTCTATCAGGTTTGCGAA
GGTGTTGCGAAGGCCAGCCATGCCTCCCACACAGCTGCCCAGGCTGGGCTTCCTGACAAGCTTGTGGCTCGTGGCAAGGAGGTCTCAGAC
TTGATCCGCAGTGGAAAACCCATCAAGCCTGTCAAGGATTTGCTAAAGAAGAACCAAATGGAAAATTGCCAGACATTAGTGGATAAGTTT
ATGAAACTGGATTTGGAAGATCCTAACCTGGACTTGAACGTTTTCATGAGCCAGGAAGTGCTGCCTGCTGCCACCAGCATCCTCTGAGAG
TCCTTCCAGTGTCCTCCCCAGCCTCCTGAGACTCCGGTGGGCTGCCATGCCCTCTTTGTTTCCTTATCTCCCTCAGACGCAGAGTTTTTA

>80382_80382_6_SENP2-MSH5_SENP2_chr3_185316812_ENST00000296257_MSH5_chr6_31726543_ENST00000431848_length(amino acids)=625AA_BP=196
MRMELSGRAGGGDVRSGGGRGPLVALGTLYLWALESRHKSATELWRWWLRRRRRQRRRQLWGLRLGVCRPPLLLGPGMYRWLVRILGTIF
RFCDRSVPPARALLKRRRSDSTLFSTVDTDEIPAKRPRLDCFIHQVKNSLYNAASLFGFPFQLTTKPMVTSACNGTRNVAPSGEVFSNSS
SCELTGSGSWNNMLKLEKRRLMGLPSFLTEVARKELENLDSRIPSCSVIYIPLIGFLLSIPRLPSMVEASDFEINGLDFMFLSEEKLHYR
SARTKELDALLGDLHCEIRDQETLLMYQLQCQVLARAAVLTRVLDLASRLDVLLALASAARDYGYSRPRYSPQVLGVRIQNGRHPLMELC
ARTFVPNSTECGGDKGRVKVITGPNSSGKSIYLKQVGLITFMALVGSFVPAEEAEIGAVDAIFTRIHSCESISLGLSTFMIDLNQVAKAV
NNATAQSLVLIDEFGKGTNTVDGLALLAAVLRHWLARGPTCPHIFVATNFLSLVQLQLLPQGPLVQYLTMETCEDGNDLVFFYQVCEGVA

--------------------------------------------------------------
>80382_80382_7_SENP2-MSH5_SENP2_chr3_185316812_ENST00000296257_MSH5_chr6_31726543_ENST00000534153_length(transcript)=3261nt_BP=598nt
GTGCGCAGATTGAGAATGGAGCTTTCCGGTCGGGCGGGAGGAGGTGACGTCAGGAGTGGTGGCGGGCGGGGGCCTCTGGTAGCCCTGGGG
ACGCTGTATCTGTGGGCTCTTGAATCGCGTCACAAATCAGCGACCGAACTCTGGCGGTGGTGGTTAAGACGGCGAAGGCGGCAGCGGCGG
CGACAGCTCTGGGGTTTGCGTCTCGGGGTGTGTCGGCCGCCGCTGCTGCTTGGGCCTGGTATGTACAGATGGCTGGTTAGGATTCTCGGC
ACCATTTTCCGTTTCTGCGACCGGTCGGTGCCCCCTGCCCGGGCCCTCCTGAAGAGGCGGCGCTCAGACAGCACTCTGTTTTCTACAGTG
GACACTGATGAAATACCAGCCAAAAGACCAAGATTAGATTGCTTTATTCACCAAGTGAAAAACAGTCTCTACAATGCTGCCAGCTTATTT
GGATTCCCATTCCAGCTGACCACAAAGCCCATGGTAACTTCTGCTTGTAATGGAACACGGAATGTGGCCCCTTCAGGAGAGGTATTTTCG
AACTCTTCATCTTGTGAACTGACAGGTTCTGGATCCTGGAACAACATGCTGAAACTGGAAAAGCGAAGACTGATGGGACTTCCCAGTTTC
CTTACTGAGGTTGCCCGCAAGGAGCTGGAGAATCTGGACTCCCGTATTCCTTCATGCAGTGTCATCTACATCCCTCTGATTGGCTTCCTT
CTTTCTATTCCCCGCCTGCCTTCCATGGTAGAGGCCAGTGACTTTGAGATTAATGGACTGGACTTCATGTTTCTCTCAGAGGAGAAGCTG
CACTATCGTAGTGCCCGAACCAAGGAGCTGGATGCATTGCTGGGGGACCTGCACTGCGAGATCCGGGACCAGGAGACGCTGCTGATGTAC
CAGCTACAGTGCCAGGTGCTGGCACGAGCAGCTGTCTTAACCCGAGTATTGGACCTTGCCTCCCGCCTGGACGTCCTGCTGGCTCTTGCC
AGTGCTGCCCGGGACTATGGCTACTCAAGGCCGCGTTACTCCCCACAAGTCCTTGGGGTACGAATCCAGAATGGCAGACATCCTCTGATG
GAACTCTGTGCCCGAACCTTTGTGCCCAACTCCACAGAATGTGGTGGGGACAAAGGGAGGGTCAAAGTCATCACTGGACCCAACTCATCA
GGGAAGAGCATATACCTCAAACAGGTAGGCTTGATCACATTCATGGCCCTGGTAGGCAGCTTTGTGCCAGCAGAGGAGGCCGAAATTGGG
GCAGTAGACGCCATCTTCACACGAATTCATAGCTGCGAATCCATCTCCCTTGGCCTCTCCACCTTCATGATCGACCTCAACCAGGTGGCG
AAAGCAGTGAACAATGCCACTGCACAGTCGCTGGTCCTTATTGATGAATTTGGAAAGGGAACCAACACGGTGGATGGGCTCGCGCTTCTG
GCCGCTGTGCTCCGACACTGGCTGGCACGTGGACCCACATGCCCCCACATCTTTGTGGCCACCAACTTTCTGAGCCTTGTTCAGCTACAA
CTGCTGCCACAAGGGCCCCTGGTGCAGTATTTGACCATGGAGACCTGTGAGGATGGCAACGATCTTGTCTTCTTCTATCAGGTTTGCGAA
GGTGTTGCGAAGGCCAGCCATGCCTCCCACACAGCTGCCCAGGCTGGGCTTCCTGACAAGCTTGTGGCTCGTGGCAAGGAGGTCTCAGAC
TTGATCCGCAGTGGAAAACCCATCAAGCCTGTCAAGGATTTGCTAAAGAAGAACCAAATGGAAAATTGCCAGACATTAGTGGATAAGTTT
ATGAAACTGGATTTGGAAGATCCTAACCTGGACTTGAACGTTTTCATGAGCCAGGAAGTGCTGCCTGCTGCCACCAGCATCCTCTGAGAG
TCCTTCCAGTGTCCTCCCCAGCCTCCTGAGACTCCGGTGGGCTGCCATGCCCTCTTTGTTTCCTTATCTCCCTCAGACGCAGAGTTTTTA
GTTTCTCTAGAAATTTTGTTTCATATTAGGAATAAAGTTTATTTTGAAGAAAGATATTGTTTCTTTAGTCTCAAAACAAGAGACTAGGAA
AGATCCAAAACACAGAGCAGGAGTCCACAGGGGAACCTGCCCTGCCTCAGTAAAAATACAGTGTTGTTGCTGTAGGAAGACTCCCGGATT
CTACCCCAGGATACTTCATGAGAACGAACCCCTTCAGAGAGGCCCTACAAAACAGATTAGAGGGAAGACAGAGGGGTCCAAGGGAGATGG
TCTCTCTTCTCAAGTAGGAACACCCCAGCCTCAGACAGACACAGCAGGAAGGGGCCTGAGAGGCTGACAGAGGCAGGATGGGTGCAAGGC
AGGGGTGGAGGGGAGGGACCAGCCCGGGCTGCACCAGTGGGAGTGGCTCCACCCTTCCCACCTCAGAGCCATGGGGAGCCAGGGCTCTGG
CGGGGTGCCCTTGGTGCAGGCTCCCTACACAGTCCTGCTGCTGCCGCTGGGGACAAGCCGCCAAGACCCAGGGGCCCAGAGCTTCTTCCT
TTGGCTACGCAGGATGCAGGCTCTGGAGAGAGAACAGGATGCCCTGTGGCAGGGTCTGGAGCTGCTACAGCATGGCCAGGCCTGGTTTGA
AGACCATCTGAGGGAGGCACAGCGACAGCAGCTGCATCTAGGGGCCCTTGGTGAGAATTTTCTAACAGATTTACACTCAGAGCCTGGTCG
CCCCCCGTTAGCCCAGATTCAAAAGGTGAACATCTGTTTGCAGAATCTGATTCATGAGAAGTTCTCCCCAAGTCCACTGAACAAGGCTAG
TTCCTGCACCACCCAGGATTCAAAGGAAAGACGAAGGGAGCAGAACTTGTGGCAGCAACAGGAGTTGTCAAGGCAGCAGAAAGGAGTCAC
CCAGCCAAAGGAGGAGATGGCTCAGCGGGGCTGCACCAAGGGGCCAAGAGGCCCTACCCGTGTCTAAACCCTCCTCTCACTCCCCTAAGC
CTGGTGAAAGAGTCAGAAGCCCCAGGCTCCTTTTTCTGTTTCTTAACTCAACAGCTAAAAAATGGCTCCAGGTAGTGAGTCAATGAAGTT
CAGACATGTTGGTGTAAAGTTTCTCCTCTGCTCCTGAAAACTTCATCTTCTTGGTGTCTCATGTCCTCATTCTCCCCTATATGACATGCA
AAAACGATCTTTCTTTGAAATCCCTCTGGGAAGAAGCATGTTTATTGAAACTGTCCTTCAGCCTTAAATACAAAAATAAAACTGAAACTG

>80382_80382_7_SENP2-MSH5_SENP2_chr3_185316812_ENST00000296257_MSH5_chr6_31726543_ENST00000534153_length(amino acids)=625AA_BP=196
MRMELSGRAGGGDVRSGGGRGPLVALGTLYLWALESRHKSATELWRWWLRRRRRQRRRQLWGLRLGVCRPPLLLGPGMYRWLVRILGTIF
RFCDRSVPPARALLKRRRSDSTLFSTVDTDEIPAKRPRLDCFIHQVKNSLYNAASLFGFPFQLTTKPMVTSACNGTRNVAPSGEVFSNSS
SCELTGSGSWNNMLKLEKRRLMGLPSFLTEVARKELENLDSRIPSCSVIYIPLIGFLLSIPRLPSMVEASDFEINGLDFMFLSEEKLHYR
SARTKELDALLGDLHCEIRDQETLLMYQLQCQVLARAAVLTRVLDLASRLDVLLALASAARDYGYSRPRYSPQVLGVRIQNGRHPLMELC
ARTFVPNSTECGGDKGRVKVITGPNSSGKSIYLKQVGLITFMALVGSFVPAEEAEIGAVDAIFTRIHSCESISLGLSTFMIDLNQVAKAV
NNATAQSLVLIDEFGKGTNTVDGLALLAAVLRHWLARGPTCPHIFVATNFLSLVQLQLLPQGPLVQYLTMETCEDGNDLVFFYQVCEGVA

--------------------------------------------------------------
>80382_80382_8_SENP2-MSH5_SENP2_chr3_185316812_ENST00000545472_MSH5_chr6_31726543_ENST00000375703_length(transcript)=1793nt_BP=356nt
AAGGATAATCCCACTCCTTGGCCAGTGGATGGACAGTCACCCATGTCTCTACTGTGGACCACAGGACAGCGAAGGCACCAACTGGCAGAC
AAGTCCCAGCACTCTGTTTTCTACAGTGGACACTGATGAAATACCAGCCAAAAGACCAAGATTAGATTGCTTTATTCACCAAGTGAAAAA
CAGTCTCTACAATGCTGCCAGCTTATTTGGATTCCCATTCCAGCTGACCACAAAGCCCATGGTAACTTCTGCTTGTAATGGAACACGGAA
TGTGGCCCCTTCAGGAGAGGTATTTTCGAACTCTTCATCTTGTGAACTGACAGGTTCTGGATCCTGGAACAACATGCTGAAACTGGAAAA
GCGAAGACTGATGGGACTTCCCAGTTTCCTTACTGAGGTTGCCCGCAAGGAGCTGGAGAATCTGGACTCCCGTATTCCTTCATGCAGTGT
CATCTACATCCCTCTGATTGGCTTCCTTCTTTCTATTCCCCGCCTGCCTTCCATGGTAGAGGCCAGTGACTTTGAGATTAATGGACTGGA
CTTCATGTTTCTCTCAGAGGAGAAGCTGCACTATCGTAGTGCCCGAACCAAGGAGCTGGATGCATTGCTGGGGGACCTGCACTGCGAGAT
CCGGGACCAGGAGACGCTGCTGATGTACCAGCTACAGTGCCAGGTGCTGGCACGAGCAGCTGTCTTAACCCGAGTATTGGACCTTGCCTC
CCGCCTGGACGTCCTGCTGGCTCTTGCCAGTGCTGCCCGGGACTATGGCTACTCAAGGCCGCGTTACTCCCCACAAGTCCTTGGGGTACG
AATCCAGAATGGCAGACATCCTCTGATGGAACTCTGTGCCCGAACCTTTGTGCCCAACTCCACAGAATGTGGTGGGGACAAAGGGAGGGT
CAAAGTCATCACTGGACCCAACTCATCAGGGAAGAGCATATACCTCAAACAGGTAGGCTTGATCACATTCATGGCCCTGGTAGGCAGCTT
TGTGCCAGCAGAGGAGGCCGAAATTGGGGCAGTAGACGCCATCTTCACACGAATTCATAGCTGCGAATCCATCTCCCTTGGCCTCTCCAC
CTTCATGATCGACCTCAACCAGCAGGTGGCGAAAGCAGTGAACAATGCCACTGCACAGTCGCTGGTCCTTATTGATGAATTTGGAAAGGG
AACCAACACGGTGGATGGGCTCGCGCTTCTGGCCGCTGTGCTCCGACACTGGCTGGCACGTGGACCCACATGCCCCCACATCTTTGTGGC
CACCAACTTTCTGAGCCTTGTTCAGCTACAACTGCTGCCACAAGGGCCCCTGGTGCAGTATTTGACCATGGAGACCTGTGAGGATGGCAA
CGATCTTGTCTTCTTCTATCAGGTTTGCGAAGGTGTTGCGAAGGCCAGCCATGCCTCCCACACAGCTGCCCAGGCTGGGCTTCCTGACAA
GCTTGTGGCTCGTGGCAAGGAGGTCTCAGACTTGATCCGCAGTGGAAAACCCATCAAGCCTGTCAAGGATTTGCTAAAGAAGAACCAAAT
GGAAAATTGCCAGACATTAGTGGATAAGTTTATGAAACTGGATTTGGAAGATCCTAACCTGGACTTGAACGTTTTCATGAGCCAGGAAGT
GCTGCCTGCTGCCACCAGCATCCTCTGAGAGTCCTTCCAGTGTCCTCCCCAGCCTCCTGAGACTCCGGTGGGCTGCCATGCCCTCTTTGT

>80382_80382_8_SENP2-MSH5_SENP2_chr3_185316812_ENST00000545472_MSH5_chr6_31726543_ENST00000375703_length(amino acids)=539AA_BP=109
MDSHPCLYCGPQDSEGTNWQTSPSTLFSTVDTDEIPAKRPRLDCFIHQVKNSLYNAASLFGFPFQLTTKPMVTSACNGTRNVAPSGEVFS
NSSSCELTGSGSWNNMLKLEKRRLMGLPSFLTEVARKELENLDSRIPSCSVIYIPLIGFLLSIPRLPSMVEASDFEINGLDFMFLSEEKL
HYRSARTKELDALLGDLHCEIRDQETLLMYQLQCQVLARAAVLTRVLDLASRLDVLLALASAARDYGYSRPRYSPQVLGVRIQNGRHPLM
ELCARTFVPNSTECGGDKGRVKVITGPNSSGKSIYLKQVGLITFMALVGSFVPAEEAEIGAVDAIFTRIHSCESISLGLSTFMIDLNQQV
AKAVNNATAQSLVLIDEFGKGTNTVDGLALLAAVLRHWLARGPTCPHIFVATNFLSLVQLQLLPQGPLVQYLTMETCEDGNDLVFFYQVC

--------------------------------------------------------------
>80382_80382_9_SENP2-MSH5_SENP2_chr3_185316812_ENST00000545472_MSH5_chr6_31726543_ENST00000375740_length(transcript)=1703nt_BP=356nt
AAGGATAATCCCACTCCTTGGCCAGTGGATGGACAGTCACCCATGTCTCTACTGTGGACCACAGGACAGCGAAGGCACCAACTGGCAGAC
AAGTCCCAGCACTCTGTTTTCTACAGTGGACACTGATGAAATACCAGCCAAAAGACCAAGATTAGATTGCTTTATTCACCAAGTGAAAAA
CAGTCTCTACAATGCTGCCAGCTTATTTGGATTCCCATTCCAGCTGACCACAAAGCCCATGGTAACTTCTGCTTGTAATGGAACACGGAA
TGTGGCCCCTTCAGGAGAGGTATTTTCGAACTCTTCATCTTGTGAACTGACAGGTTCTGGATCCTGGAACAACATGCTGAAACTGGAAAA
GCGAAGACTGATGGGACTTCCCAGTTTCCTTACTGAGGTTGCCCGCAAGGAGCTGGAGAATCTGGACTCCCGTATTCCTTCATGCAGTGT
CATCTACATCCCTCTGATTGGCTTCCTTCTTTCTATTCCCCGCCTGCCTTCCATGGTAGAGGCCAGTGACTTTGAGATTAATGGACTGGA
CTTCATGTTTCTCTCAGAGGAGAAGCTGCACTATCGTAGTGCCCGAACCAAGGAGCTGGATGCATTGCTGGGGGACCTGCACTGCGAGAT
CCGGGACCAGGAGACGCTGCTGATGTACCAGCTACAGTGCCAGGTGCTGGCACGAGCAGCTGTCTTAACCCGAGTATTGGACCTTGCCTC
CCGCCTGGACGTCCTGCTGGCTCTTGCCAGTGCTGCCCGGGACTATGGCTACTCAAGGCCGCGTTACTCCCCACAAGTCCTTGGGGTACG
AATCCAGAATGGCAGACATCCTCTGATGGAACTCTGTGCCCGAACCTTTGTGCCCAACTCCACAGAATGTGGTGGGGACAAAGGGAGGGT
CAAAGTCATCACTGGACCCAACTCATCAGGGAAGAGCATATACCTCAAACAGGTAGGCTTGATCACATTCATGGCCCTGGTAGGCAGCTT
TGTGCCAGCAGAGGAGGCCGAAATTGGGGCAGTAGACGCCATCTTCACACGAATTCATAGCTGCGAATCCATCTCCCTTGGCCTCTCCAC
CTTCATGATCGACCTCAACCAGCAGGTGGCGAAAGCAGTGAACAATGCCACTGCACAGTCGCTGGTCCTTATTGATGAATTTGGAAAGGG
AACCAACACGGTGGATGGGCTCGCGCTTCTGGCCGCTGTGCTCCGACACTGGCTGGCACGTGGACCCACATGCCCCCACATCTTTGTGGC
CACCAACTTTCTGAGCCTTGTTCAGCTACAACTGCTGCCACAAGGGCCCCTGGTGCAGTATTTGACCATGGAGACCTGTGAGGATGGCAA
CGATCTTGTCTTCTTCTATCAGGTCTCAGACTTGATCCGCAGTGGAAAACCCATCAAGCCTGTCAAGGATTTGCTAAAGAAGAACCAAAT
GGAAAATTGCCAGACATTAGTGGATAAGTTTATGAAACTGGATTTGGAAGATCCTAACCTGGACTTGAACGTTTTCATGAGCCAGGAAGT
GCTGCCTGCTGCCACCAGCATCCTCTGAGAGTCCTTCCAGTGTCCTCCCCAGCCTCCTGAGACTCCGGTGGGCTGCCATGCCCTCTTTGT

>80382_80382_9_SENP2-MSH5_SENP2_chr3_185316812_ENST00000545472_MSH5_chr6_31726543_ENST00000375740_length(amino acids)=509AA_BP=109
MDSHPCLYCGPQDSEGTNWQTSPSTLFSTVDTDEIPAKRPRLDCFIHQVKNSLYNAASLFGFPFQLTTKPMVTSACNGTRNVAPSGEVFS
NSSSCELTGSGSWNNMLKLEKRRLMGLPSFLTEVARKELENLDSRIPSCSVIYIPLIGFLLSIPRLPSMVEASDFEINGLDFMFLSEEKL
HYRSARTKELDALLGDLHCEIRDQETLLMYQLQCQVLARAAVLTRVLDLASRLDVLLALASAARDYGYSRPRYSPQVLGVRIQNGRHPLM
ELCARTFVPNSTECGGDKGRVKVITGPNSSGKSIYLKQVGLITFMALVGSFVPAEEAEIGAVDAIFTRIHSCESISLGLSTFMIDLNQQV
AKAVNNATAQSLVLIDEFGKGTNTVDGLALLAAVLRHWLARGPTCPHIFVATNFLSLVQLQLLPQGPLVQYLTMETCEDGNDLVFFYQVS

--------------------------------------------------------------
>80382_80382_10_SENP2-MSH5_SENP2_chr3_185316812_ENST00000545472_MSH5_chr6_31726543_ENST00000375742_length(transcript)=1784nt_BP=356nt
AAGGATAATCCCACTCCTTGGCCAGTGGATGGACAGTCACCCATGTCTCTACTGTGGACCACAGGACAGCGAAGGCACCAACTGGCAGAC
AAGTCCCAGCACTCTGTTTTCTACAGTGGACACTGATGAAATACCAGCCAAAAGACCAAGATTAGATTGCTTTATTCACCAAGTGAAAAA
CAGTCTCTACAATGCTGCCAGCTTATTTGGATTCCCATTCCAGCTGACCACAAAGCCCATGGTAACTTCTGCTTGTAATGGAACACGGAA
TGTGGCCCCTTCAGGAGAGGTATTTTCGAACTCTTCATCTTGTGAACTGACAGGTTCTGGATCCTGGAACAACATGCTGAAACTGGAAAA
GCGAAGACTGATGGGACTTCCCAGTTTCCTTACTGAGGTTGCCCGCAAGGAGCTGGAGAATCTGGACTCCCGTATTCCTTCATGCAGTGT
CATCTACATCCCTCTGATTGGCTTCCTTCTTTCTATTCCCCGCCTGCCTTCCATGGTAGAGGCCAGTGACTTTGAGATTAATGGACTGGA
CTTCATGTTTCTCTCAGAGGAGAAGCTGCACTATCGTAGTGCCCGAACCAAGGAGCTGGATGCATTGCTGGGGGACCTGCACTGCGAGAT
CCGGGACCAGGAGACGCTGCTGATGTACCAGCTACAGTGCCAGGTGCTGGCACGAGCAGCTGTCTTAACCCGAGTATTGGACCTTGCCTC
CCGCCTGGACGTCCTGCTGGCTCTTGCCAGTGCTGCCCGGGACTATGGCTACTCAAGGCCGCGTTACTCCCCACAAGTCCTTGGGGTACG
AATCCAGAATGGCAGACATCCTCTGATGGAACTCTGTGCCCGAACCTTTGTGCCCAACTCCACAGAATGTGGTGGGGACAAAGGGAGGGT
CAAAGTCATCACTGGACCCAACTCATCAGGGAAGAGCATATACCTCAAACAGGTAGGCTTGATCACATTCATGGCCCTGGTAGGCAGCTT
TGTGCCAGCAGAGGAGGCCGAAATTGGGGCAGTAGACGCCATCTTCACACGAATTCATAGCTGCGAATCCATCTCCCTTGGCCTCTCCAC
CTTCATGATCGACCTCAACCAGGTGGCGAAAGCAGTGAACAATGCCACTGCACAGTCGCTGGTCCTTATTGATGAATTTGGAAAGGGAAC
CAACACGGTGGATGGGCTCGCGCTTCTGGCCGCTGTGCTCCGACACTGGCTGGCACGTGGACCCACATGCCCCCACATCTTTGTGGCCAC
CAACTTTCTGAGCCTTGTTCAGCTACAACTGCTGCCACAAGGGCCCCTGGTGCAGTATTTGACCATGGAGACCTGTGAGGATGGCAACGA
TCTTGTCTTCTTCTATCAGGTTTGCGAAGGTGTTGCGAAGGCCAGCCATGCCTCCCACACAGCTGCCCAGGCTGGGCTTCCTGACAAGCT
TGTGGCTCGTGGCAAGGAGGTCTCAGACTTGATCCGCAGTGGAAAACCCATCAAGCCTGTCAAGGATTTGCTAAAGAAGAACCAAATGGA
AAATTGCCAGACATTAGTGGATAAGTTTATGAAACTGGATTTGGAAGATCCTAACCTGGACTTGAACGTTTTCATGAGCCAGGAAGTGCT
GCCTGCTGCCACCAGCATCCTCTGAGAGTCCTTCCAGTGTCCTCCCCAGCCTCCTGAGACTCCGGTGGGCTGCCATGCCCTCTTTGTTTC

>80382_80382_10_SENP2-MSH5_SENP2_chr3_185316812_ENST00000545472_MSH5_chr6_31726543_ENST00000375742_length(amino acids)=538AA_BP=109
MDSHPCLYCGPQDSEGTNWQTSPSTLFSTVDTDEIPAKRPRLDCFIHQVKNSLYNAASLFGFPFQLTTKPMVTSACNGTRNVAPSGEVFS
NSSSCELTGSGSWNNMLKLEKRRLMGLPSFLTEVARKELENLDSRIPSCSVIYIPLIGFLLSIPRLPSMVEASDFEINGLDFMFLSEEKL
HYRSARTKELDALLGDLHCEIRDQETLLMYQLQCQVLARAAVLTRVLDLASRLDVLLALASAARDYGYSRPRYSPQVLGVRIQNGRHPLM
ELCARTFVPNSTECGGDKGRVKVITGPNSSGKSIYLKQVGLITFMALVGSFVPAEEAEIGAVDAIFTRIHSCESISLGLSTFMIDLNQVA
KAVNNATAQSLVLIDEFGKGTNTVDGLALLAAVLRHWLARGPTCPHIFVATNFLSLVQLQLLPQGPLVQYLTMETCEDGNDLVFFYQVCE

--------------------------------------------------------------
>80382_80382_11_SENP2-MSH5_SENP2_chr3_185316812_ENST00000545472_MSH5_chr6_31726543_ENST00000375750_length(transcript)=1790nt_BP=356nt
AAGGATAATCCCACTCCTTGGCCAGTGGATGGACAGTCACCCATGTCTCTACTGTGGACCACAGGACAGCGAAGGCACCAACTGGCAGAC
AAGTCCCAGCACTCTGTTTTCTACAGTGGACACTGATGAAATACCAGCCAAAAGACCAAGATTAGATTGCTTTATTCACCAAGTGAAAAA
CAGTCTCTACAATGCTGCCAGCTTATTTGGATTCCCATTCCAGCTGACCACAAAGCCCATGGTAACTTCTGCTTGTAATGGAACACGGAA
TGTGGCCCCTTCAGGAGAGGTATTTTCGAACTCTTCATCTTGTGAACTGACAGGTTCTGGATCCTGGAACAACATGCTGAAACTGGAAAA
GCGAAGACTGATGGGACTTCCCAGTTTCCTTACTGAGGTTGCCCGCAAGGAGCTGGAGAATCTGGACTCCCGTATTCCTTCATGCAGTGT
CATCTACATCCCTCTGATTGGCTTCCTTCTTTCTATTCCCCGCCTGCCTTCCATGGTAGAGGCCAGTGACTTTGAGATTAATGGACTGGA
CTTCATGTTTCTCTCAGAGGAGAAGCTGCACTATCGTAGTGCCCGAACCAAGGAGCTGGATGCATTGCTGGGGGACCTGCACTGCGAGAT
CCGGGACCAGGAGACGCTGCTGATGTACCAGCTACAGTGCCAGGTGCTGGCACGAGCAGCTGTCTTAACCCGAGTATTGGACCTTGCCTC
CCGCCTGGACGTCCTGCTGGCTCTTGCCAGTGCTGCCCGGGACTATGGCTACTCAAGGCCGCGTTACTCCCCACAAGTCCTTGGGGTACG
AATCCAGAATGGCAGACATCCTCTGATGGAACTCTGTGCCCGAACCTTTGTGCCCAACTCCACAGAATGTGGTGGGGACAAAGGGAGGGT
CAAAGTCATCACTGGACCCAACTCATCAGGGAAGAGCATATACCTCAAACAGGTAGGCTTGATCACATTCATGGCCCTGGTAGGCAGCTT
TGTGCCAGCAGAGGAGGCCGAAATTGGGGCAGTAGACGCCATCTTCACACGAATTCATAGCTGCGAATCCATCTCCCTTGGCCTCTCCAC
CTTCATGATCGACCTCAACCAGGTGGCGAAAGCAGTGAACAATGCCACTGCACAGTCGCTGGTCCTTATTGATGAATTTGGAAAGGGAAC
CAACACGGTGGATGGGCTCGCGCTTCTGGCCGCTGTGCTCCGACACTGGCTGGCACGTGGACCCACATGCCCCCACATCTTTGTGGCCAC
CAACTTTCTGAGCCTTGTTCAGCTACAACTGCTGCCACAAGGGCCCCTGGTGCAGTATTTGACCATGGAGACCTGTGAGGATGGCAACGA
TCTTGTCTTCTTCTATCAGGTTTGCGAAGGTGTTGCGAAGGCCAGCCATGCCTCCCACACAGCTGCCCAGGCTGGGCTTCCTGACAAGCT
TGTGGCTCGTGGCAAGGAGGTCTCAGACTTGATCCGCAGTGGAAAACCCATCAAGCCTGTCAAGGATTTGCTAAAGAAGAACCAAATGGA
AAATTGCCAGACATTAGTGGATAAGTTTATGAAACTGGATTTGGAAGATCCTAACCTGGACTTGAACGTTTTCATGAGCCAGGAAGTGCT
GCCTGCTGCCACCAGCATCCTCTGAGAGTCCTTCCAGTGTCCTCCCCAGCCTCCTGAGACTCCGGTGGGCTGCCATGCCCTCTTTGTTTC

>80382_80382_11_SENP2-MSH5_SENP2_chr3_185316812_ENST00000545472_MSH5_chr6_31726543_ENST00000375750_length(amino acids)=538AA_BP=109
MDSHPCLYCGPQDSEGTNWQTSPSTLFSTVDTDEIPAKRPRLDCFIHQVKNSLYNAASLFGFPFQLTTKPMVTSACNGTRNVAPSGEVFS
NSSSCELTGSGSWNNMLKLEKRRLMGLPSFLTEVARKELENLDSRIPSCSVIYIPLIGFLLSIPRLPSMVEASDFEINGLDFMFLSEEKL
HYRSARTKELDALLGDLHCEIRDQETLLMYQLQCQVLARAAVLTRVLDLASRLDVLLALASAARDYGYSRPRYSPQVLGVRIQNGRHPLM
ELCARTFVPNSTECGGDKGRVKVITGPNSSGKSIYLKQVGLITFMALVGSFVPAEEAEIGAVDAIFTRIHSCESISLGLSTFMIDLNQVA
KAVNNATAQSLVLIDEFGKGTNTVDGLALLAAVLRHWLARGPTCPHIFVATNFLSLVQLQLLPQGPLVQYLTMETCEDGNDLVFFYQVCE

--------------------------------------------------------------
>80382_80382_12_SENP2-MSH5_SENP2_chr3_185316812_ENST00000545472_MSH5_chr6_31726543_ENST00000375755_length(transcript)=1948nt_BP=356nt
AAGGATAATCCCACTCCTTGGCCAGTGGATGGACAGTCACCCATGTCTCTACTGTGGACCACAGGACAGCGAAGGCACCAACTGGCAGAC
AAGTCCCAGCACTCTGTTTTCTACAGTGGACACTGATGAAATACCAGCCAAAAGACCAAGATTAGATTGCTTTATTCACCAAGTGAAAAA
CAGTCTCTACAATGCTGCCAGCTTATTTGGATTCCCATTCCAGCTGACCACAAAGCCCATGGTAACTTCTGCTTGTAATGGAACACGGAA
TGTGGCCCCTTCAGGAGAGGTATTTTCGAACTCTTCATCTTGTGAACTGACAGGTTCTGGATCCTGGAACAACATGCTGAAACTGGAAAA
GCGAAGACTGATGGGACTTCCCAGTTTCCTTACTGAGGTTGCCCGCAAGGAGCTGGAGAATCTGGACTCCCGTATTCCTTCATGCAGTGT
CATCTACATCCCTCTGATTGGCTTCCTTCTTTCTATTCCCCGCCTGCCTTCCATGGTAGAGGCCAGTGACTTTGAGATTAATGGACTGGA
CTTCATGTTTCTCTCAGAGGAGAAGCTGCACTATCGTAGTGCCCGAACCAAGGAGCTGGATGCATTGCTGGGGGACCTGCACTGCGAGAT
CCGGGACCAGGAGACGCTGCTGATGTACCAGCTACAGTGCCAGGTGCTGGCACGAGCAGCTGTCTTAACCCGAGTATTGGACCTTGCCTC
CCGCCTGGACGTCCTGCTGGCTCTTGCCAGTGCTGCCCGGGACTATGGCTACTCAAGGCCGCGTTACTCCCCACAAGTCCTTGGGGTACG
AATCCAGAATGGCAGACATCCTCTGATGGAACTCTGTGCCCGAACCTTTGTGCCCAACTCCACAGAATGTGGTGGGGACAAAGGGAGGGT
CAAAGTCATCACTGGACCCAACTCATCAGGGAAGAGCATATACCTCAAACAGGTAGGCTTGATCACATTCATGGCCCTGGTAGGCAGCTT
TGTGCCAGCAGAGGAGGCCGAAATTGGGGCAGTAGACGCCATCTTCACACGAATTCATAGCTGCGAATCCATCTCCCTTGGCCTCTCCAC
CTTCATGATCGACCTCAACCAGGTGGCGAAAGCAGTGAACAATGCCACTGCACAGTCGCTGGTCCTTATTGATGAATTTGGAAAGGGAAC
CAACACGGTGGATGGGCTCGCGCTTCTGGCCGCTGTGCTCCGACACTGGCTGGCACGTGGACCCACATGCCCCCACATCTTTGTGGCCAC
CAACTTTCTGAGCCTTGTTCAGCTACAACTGCTGCCACAAGGGCCCCTGGTGCAGTATTTGACCATGGAGACCTGTGAGGATGGCAACGA
TCTTGTCTTCTTCTATCAGGTTTGCGAAGGTGTTGCGAAGGCCAGCCATGCCTCCCACACAGCTGCCCAGGCTGGGCTTCCTGACAAGCT
TGTGGCTCGTGGCAAGGAGGTCTCAGACTTGATCCGCAGTGGAAAACCCATCAAGCCTGTCAAGGATTTGCTAAAGAAGAACCAAATGGA
AAATTGCCAGACATTAGTGGATAAGTTTATGAAACTGGATTTGGAAGATCCTAACCTGGACTTGAACGTTTTCATGAGCCAGGAAGTGCT
GCCTGCTGCCACCAGCATCCTCTGAGAGTCCTTCCAGTGTCCTCCCCAGCCTCCTGAGACTCCGGTGGGCTGCCATGCCCTCTTTGTTTC
CTTATCTCCCTCAGACGCAGAGTTTTTAGTTTCTCTAGAAATTTTGTTTCATATTAGGAATAAAGTTTATTTTGAAGAAAGATATTGTTT
CTTTAGTCTCAAAACAAGAGACTAGGAAAGATCCAAAACACAGAGCAGGAGTCCACAGGGGAACCTGCCCTGCCTCAGTAAAAATACAGT

>80382_80382_12_SENP2-MSH5_SENP2_chr3_185316812_ENST00000545472_MSH5_chr6_31726543_ENST00000375755_length(amino acids)=538AA_BP=109
MDSHPCLYCGPQDSEGTNWQTSPSTLFSTVDTDEIPAKRPRLDCFIHQVKNSLYNAASLFGFPFQLTTKPMVTSACNGTRNVAPSGEVFS
NSSSCELTGSGSWNNMLKLEKRRLMGLPSFLTEVARKELENLDSRIPSCSVIYIPLIGFLLSIPRLPSMVEASDFEINGLDFMFLSEEKL
HYRSARTKELDALLGDLHCEIRDQETLLMYQLQCQVLARAAVLTRVLDLASRLDVLLALASAARDYGYSRPRYSPQVLGVRIQNGRHPLM
ELCARTFVPNSTECGGDKGRVKVITGPNSSGKSIYLKQVGLITFMALVGSFVPAEEAEIGAVDAIFTRIHSCESISLGLSTFMIDLNQVA
KAVNNATAQSLVLIDEFGKGTNTVDGLALLAAVLRHWLARGPTCPHIFVATNFLSLVQLQLLPQGPLVQYLTMETCEDGNDLVFFYQVCE

--------------------------------------------------------------
>80382_80382_13_SENP2-MSH5_SENP2_chr3_185316812_ENST00000545472_MSH5_chr6_31726543_ENST00000431848_length(transcript)=1749nt_BP=356nt
AAGGATAATCCCACTCCTTGGCCAGTGGATGGACAGTCACCCATGTCTCTACTGTGGACCACAGGACAGCGAAGGCACCAACTGGCAGAC
AAGTCCCAGCACTCTGTTTTCTACAGTGGACACTGATGAAATACCAGCCAAAAGACCAAGATTAGATTGCTTTATTCACCAAGTGAAAAA
CAGTCTCTACAATGCTGCCAGCTTATTTGGATTCCCATTCCAGCTGACCACAAAGCCCATGGTAACTTCTGCTTGTAATGGAACACGGAA
TGTGGCCCCTTCAGGAGAGGTATTTTCGAACTCTTCATCTTGTGAACTGACAGGTTCTGGATCCTGGAACAACATGCTGAAACTGGAAAA
GCGAAGACTGATGGGACTTCCCAGTTTCCTTACTGAGGTTGCCCGCAAGGAGCTGGAGAATCTGGACTCCCGTATTCCTTCATGCAGTGT
CATCTACATCCCTCTGATTGGCTTCCTTCTTTCTATTCCCCGCCTGCCTTCCATGGTAGAGGCCAGTGACTTTGAGATTAATGGACTGGA
CTTCATGTTTCTCTCAGAGGAGAAGCTGCACTATCGTAGTGCCCGAACCAAGGAGCTGGATGCATTGCTGGGGGACCTGCACTGCGAGAT
CCGGGACCAGGAGACGCTGCTGATGTACCAGCTACAGTGCCAGGTGCTGGCACGAGCAGCTGTCTTAACCCGAGTATTGGACCTTGCCTC
CCGCCTGGACGTCCTGCTGGCTCTTGCCAGTGCTGCCCGGGACTATGGCTACTCAAGGCCGCGTTACTCCCCACAAGTCCTTGGGGTACG
AATCCAGAATGGCAGACATCCTCTGATGGAACTCTGTGCCCGAACCTTTGTGCCCAACTCCACAGAATGTGGTGGGGACAAAGGGAGGGT
CAAAGTCATCACTGGACCCAACTCATCAGGGAAGAGCATATACCTCAAACAGGTAGGCTTGATCACATTCATGGCCCTGGTAGGCAGCTT
TGTGCCAGCAGAGGAGGCCGAAATTGGGGCAGTAGACGCCATCTTCACACGAATTCATAGCTGCGAATCCATCTCCCTTGGCCTCTCCAC
CTTCATGATCGACCTCAACCAGGTGGCGAAAGCAGTGAACAATGCCACTGCACAGTCGCTGGTCCTTATTGATGAATTTGGAAAGGGAAC
CAACACGGTGGATGGGCTCGCGCTTCTGGCCGCTGTGCTCCGACACTGGCTGGCACGTGGACCCACATGCCCCCACATCTTTGTGGCCAC
CAACTTTCTGAGCCTTGTTCAGCTACAACTGCTGCCACAAGGGCCCCTGGTGCAGTATTTGACCATGGAGACCTGTGAGGATGGCAACGA
TCTTGTCTTCTTCTATCAGGTTTGCGAAGGTGTTGCGAAGGCCAGCCATGCCTCCCACACAGCTGCCCAGGCTGGGCTTCCTGACAAGCT
TGTGGCTCGTGGCAAGGAGGTCTCAGACTTGATCCGCAGTGGAAAACCCATCAAGCCTGTCAAGGATTTGCTAAAGAAGAACCAAATGGA
AAATTGCCAGACATTAGTGGATAAGTTTATGAAACTGGATTTGGAAGATCCTAACCTGGACTTGAACGTTTTCATGAGCCAGGAAGTGCT
GCCTGCTGCCACCAGCATCCTCTGAGAGTCCTTCCAGTGTCCTCCCCAGCCTCCTGAGACTCCGGTGGGCTGCCATGCCCTCTTTGTTTC

>80382_80382_13_SENP2-MSH5_SENP2_chr3_185316812_ENST00000545472_MSH5_chr6_31726543_ENST00000431848_length(amino acids)=538AA_BP=109
MDSHPCLYCGPQDSEGTNWQTSPSTLFSTVDTDEIPAKRPRLDCFIHQVKNSLYNAASLFGFPFQLTTKPMVTSACNGTRNVAPSGEVFS
NSSSCELTGSGSWNNMLKLEKRRLMGLPSFLTEVARKELENLDSRIPSCSVIYIPLIGFLLSIPRLPSMVEASDFEINGLDFMFLSEEKL
HYRSARTKELDALLGDLHCEIRDQETLLMYQLQCQVLARAAVLTRVLDLASRLDVLLALASAARDYGYSRPRYSPQVLGVRIQNGRHPLM
ELCARTFVPNSTECGGDKGRVKVITGPNSSGKSIYLKQVGLITFMALVGSFVPAEEAEIGAVDAIFTRIHSCESISLGLSTFMIDLNQVA
KAVNNATAQSLVLIDEFGKGTNTVDGLALLAAVLRHWLARGPTCPHIFVATNFLSLVQLQLLPQGPLVQYLTMETCEDGNDLVFFYQVCE

--------------------------------------------------------------
>80382_80382_14_SENP2-MSH5_SENP2_chr3_185316812_ENST00000545472_MSH5_chr6_31726543_ENST00000534153_length(transcript)=3019nt_BP=356nt
AAGGATAATCCCACTCCTTGGCCAGTGGATGGACAGTCACCCATGTCTCTACTGTGGACCACAGGACAGCGAAGGCACCAACTGGCAGAC
AAGTCCCAGCACTCTGTTTTCTACAGTGGACACTGATGAAATACCAGCCAAAAGACCAAGATTAGATTGCTTTATTCACCAAGTGAAAAA
CAGTCTCTACAATGCTGCCAGCTTATTTGGATTCCCATTCCAGCTGACCACAAAGCCCATGGTAACTTCTGCTTGTAATGGAACACGGAA
TGTGGCCCCTTCAGGAGAGGTATTTTCGAACTCTTCATCTTGTGAACTGACAGGTTCTGGATCCTGGAACAACATGCTGAAACTGGAAAA
GCGAAGACTGATGGGACTTCCCAGTTTCCTTACTGAGGTTGCCCGCAAGGAGCTGGAGAATCTGGACTCCCGTATTCCTTCATGCAGTGT
CATCTACATCCCTCTGATTGGCTTCCTTCTTTCTATTCCCCGCCTGCCTTCCATGGTAGAGGCCAGTGACTTTGAGATTAATGGACTGGA
CTTCATGTTTCTCTCAGAGGAGAAGCTGCACTATCGTAGTGCCCGAACCAAGGAGCTGGATGCATTGCTGGGGGACCTGCACTGCGAGAT
CCGGGACCAGGAGACGCTGCTGATGTACCAGCTACAGTGCCAGGTGCTGGCACGAGCAGCTGTCTTAACCCGAGTATTGGACCTTGCCTC
CCGCCTGGACGTCCTGCTGGCTCTTGCCAGTGCTGCCCGGGACTATGGCTACTCAAGGCCGCGTTACTCCCCACAAGTCCTTGGGGTACG
AATCCAGAATGGCAGACATCCTCTGATGGAACTCTGTGCCCGAACCTTTGTGCCCAACTCCACAGAATGTGGTGGGGACAAAGGGAGGGT
CAAAGTCATCACTGGACCCAACTCATCAGGGAAGAGCATATACCTCAAACAGGTAGGCTTGATCACATTCATGGCCCTGGTAGGCAGCTT
TGTGCCAGCAGAGGAGGCCGAAATTGGGGCAGTAGACGCCATCTTCACACGAATTCATAGCTGCGAATCCATCTCCCTTGGCCTCTCCAC
CTTCATGATCGACCTCAACCAGGTGGCGAAAGCAGTGAACAATGCCACTGCACAGTCGCTGGTCCTTATTGATGAATTTGGAAAGGGAAC
CAACACGGTGGATGGGCTCGCGCTTCTGGCCGCTGTGCTCCGACACTGGCTGGCACGTGGACCCACATGCCCCCACATCTTTGTGGCCAC
CAACTTTCTGAGCCTTGTTCAGCTACAACTGCTGCCACAAGGGCCCCTGGTGCAGTATTTGACCATGGAGACCTGTGAGGATGGCAACGA
TCTTGTCTTCTTCTATCAGGTTTGCGAAGGTGTTGCGAAGGCCAGCCATGCCTCCCACACAGCTGCCCAGGCTGGGCTTCCTGACAAGCT
TGTGGCTCGTGGCAAGGAGGTCTCAGACTTGATCCGCAGTGGAAAACCCATCAAGCCTGTCAAGGATTTGCTAAAGAAGAACCAAATGGA
AAATTGCCAGACATTAGTGGATAAGTTTATGAAACTGGATTTGGAAGATCCTAACCTGGACTTGAACGTTTTCATGAGCCAGGAAGTGCT
GCCTGCTGCCACCAGCATCCTCTGAGAGTCCTTCCAGTGTCCTCCCCAGCCTCCTGAGACTCCGGTGGGCTGCCATGCCCTCTTTGTTTC
CTTATCTCCCTCAGACGCAGAGTTTTTAGTTTCTCTAGAAATTTTGTTTCATATTAGGAATAAAGTTTATTTTGAAGAAAGATATTGTTT
CTTTAGTCTCAAAACAAGAGACTAGGAAAGATCCAAAACACAGAGCAGGAGTCCACAGGGGAACCTGCCCTGCCTCAGTAAAAATACAGT
GTTGTTGCTGTAGGAAGACTCCCGGATTCTACCCCAGGATACTTCATGAGAACGAACCCCTTCAGAGAGGCCCTACAAAACAGATTAGAG
GGAAGACAGAGGGGTCCAAGGGAGATGGTCTCTCTTCTCAAGTAGGAACACCCCAGCCTCAGACAGACACAGCAGGAAGGGGCCTGAGAG
GCTGACAGAGGCAGGATGGGTGCAAGGCAGGGGTGGAGGGGAGGGACCAGCCCGGGCTGCACCAGTGGGAGTGGCTCCACCCTTCCCACC
TCAGAGCCATGGGGAGCCAGGGCTCTGGCGGGGTGCCCTTGGTGCAGGCTCCCTACACAGTCCTGCTGCTGCCGCTGGGGACAAGCCGCC
AAGACCCAGGGGCCCAGAGCTTCTTCCTTTGGCTACGCAGGATGCAGGCTCTGGAGAGAGAACAGGATGCCCTGTGGCAGGGTCTGGAGC
TGCTACAGCATGGCCAGGCCTGGTTTGAAGACCATCTGAGGGAGGCACAGCGACAGCAGCTGCATCTAGGGGCCCTTGGTGAGAATTTTC
TAACAGATTTACACTCAGAGCCTGGTCGCCCCCCGTTAGCCCAGATTCAAAAGGTGAACATCTGTTTGCAGAATCTGATTCATGAGAAGT
TCTCCCCAAGTCCACTGAACAAGGCTAGTTCCTGCACCACCCAGGATTCAAAGGAAAGACGAAGGGAGCAGAACTTGTGGCAGCAACAGG
AGTTGTCAAGGCAGCAGAAAGGAGTCACCCAGCCAAAGGAGGAGATGGCTCAGCGGGGCTGCACCAAGGGGCCAAGAGGCCCTACCCGTG
TCTAAACCCTCCTCTCACTCCCCTAAGCCTGGTGAAAGAGTCAGAAGCCCCAGGCTCCTTTTTCTGTTTCTTAACTCAACAGCTAAAAAA
TGGCTCCAGGTAGTGAGTCAATGAAGTTCAGACATGTTGGTGTAAAGTTTCTCCTCTGCTCCTGAAAACTTCATCTTCTTGGTGTCTCAT
GTCCTCATTCTCCCCTATATGACATGCAAAAACGATCTTTCTTTGAAATCCCTCTGGGAAGAAGCATGTTTATTGAAACTGTCCTTCAGC

>80382_80382_14_SENP2-MSH5_SENP2_chr3_185316812_ENST00000545472_MSH5_chr6_31726543_ENST00000534153_length(amino acids)=538AA_BP=109
MDSHPCLYCGPQDSEGTNWQTSPSTLFSTVDTDEIPAKRPRLDCFIHQVKNSLYNAASLFGFPFQLTTKPMVTSACNGTRNVAPSGEVFS
NSSSCELTGSGSWNNMLKLEKRRLMGLPSFLTEVARKELENLDSRIPSCSVIYIPLIGFLLSIPRLPSMVEASDFEINGLDFMFLSEEKL
HYRSARTKELDALLGDLHCEIRDQETLLMYQLQCQVLARAAVLTRVLDLASRLDVLLALASAARDYGYSRPRYSPQVLGVRIQNGRHPLM
ELCARTFVPNSTECGGDKGRVKVITGPNSSGKSIYLKQVGLITFMALVGSFVPAEEAEIGAVDAIFTRIHSCESISLGLSTFMIDLNQVA
KAVNNATAQSLVLIDEFGKGTNTVDGLALLAAVLRHWLARGPTCPHIFVATNFLSLVQLQLLPQGPLVQYLTMETCEDGNDLVFFYQVCE

--------------------------------------------------------------

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Fusion Gene PPI Analysis for SENP2-MSH5


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for SENP2-MSH5


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for SENP2-MSH5


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneSENP2C0019193Hepatitis, Toxic1CTD_human
HgeneSENP2C0023893Liver Cirrhosis, Experimental1CTD_human
HgeneSENP2C0860207Drug-Induced Liver Disease1CTD_human
HgeneSENP2C1262760Hepatitis, Drug-Induced1CTD_human
HgeneSENP2C3658290Drug-Induced Acute Liver Injury1CTD_human
HgeneSENP2C4277682Chemical and Drug Induced Liver Injury1CTD_human
HgeneSENP2C4279912Chemically-Induced Liver Toxicity1CTD_human
TgeneC2239176Liver carcinoma1CTD_human
TgeneC3469524PROSTATE CANCER, SUSCEPTIBILITY TO1GENOMICS_ENGLAND
TgeneC4479510PREMATURE OVARIAN FAILURE 131CTD_human;GENOMICS_ENGLAND;UNIPROT