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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:CLIP1-RSRC2 (FusionGDB2 ID:HG6249TG65117)

Fusion Gene Summary for CLIP1-RSRC2

check button Fusion gene summary
Fusion gene informationFusion gene name: CLIP1-RSRC2
Fusion gene ID: hg6249tg65117
HgeneTgene
Gene symbol

CLIP1

RSRC2

Gene ID

6249

65117

Gene nameCAP-Gly domain containing linker protein 1arginine and serine rich coiled-coil 2
SynonymsCLIP|CLIP-170|CLIP170|CYLN1|RSN-
Cytomap('CLIP1')('RSRC2')

12q24.31

12q24.31

Type of geneprotein-codingprotein-coding
DescriptionCAP-Gly domain-containing linker protein 1cytoplasmic linker protein 1cytoplasmic linker protein 170 alpha-2cytoplasmic linker protein CLIP-170restin (Reed-Steinberg cell-expressed intermediate filament-associated protein)arginine/serine-rich coiled-coil protein 2arginine/serine-rich coiled-coil 2
Modification date2020031320200313
UniProtAcc

P30622

.
Ensembl transtripts involved in fusion geneENST00000302528, ENST00000358808, 
ENST00000361654, ENST00000537178, 
ENST00000540338, ENST00000545889, 
ENST00000536634, ENST00000540539, 
Fusion gene scores* DoF score22 X 22 X 13=62927 X 14 X 10=980
# samples 3116
** MAII scorelog2(31/6292*10)=-4.34317855014145
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(16/980*10)=-2.61470984411521
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CLIP1 [Title/Abstract] AND RSRC2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCLIP1(122825300)-RSRC2(122992994), # samples:2
CLIP1(122907068)-RSRC2(122992994), # samples:2
Anticipated loss of major functional domain due to fusion event.CLIP1-RSRC2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
CLIP1-RSRC2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
CLIP1-RSRC2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
CLIP1-RSRC2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
CLIP1-RSRC2 seems lost the major protein functional domain in Hgene partner, which is a CGC due to the frame-shifted ORF.
CLIP1-RSRC2 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
CLIP1-RSRC2 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across CLIP1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across RSRC2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-AC-A8OQ-01ACLIP1chr12

122812494

-RSRC2chr12

122992997

-
ChimerDB4LIHCTCGA-BC-A216-01ACLIP1chr12

122884328

-RSRC2chr12

122999774

-
ChimerDB4LIHCTCGA-BC-A216-01ACLIP1chr12

122907068

-RSRC2chr12

122999774

-
ChimerDB4LIHCTCGA-BC-A216CLIP1chr12

122907067

-RSRC2chr12

122999774

-
ChimerDB4SARCTCGA-QQ-A8VF-01ACLIP1chr12

122825300

-RSRC2chr12

122992994

-
ChimerDB4SKCMTCGA-D3-A51H-06ACLIP1chr12

122907068

-RSRC2chr12

122992994

-
ChimerDB4SKCMTCGA-D3-A51HCLIP1chr12

122907067

-RSRC2chr12

122992994

-


Top

Fusion Gene ORF analysis for CLIP1-RSRC2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000302528ENST00000392442CLIP1chr12

122812494

-RSRC2chr12

122992997

-
5CDS-5UTRENST00000302528ENST00000392442CLIP1chr12

122825300

-RSRC2chr12

122992994

-
5CDS-5UTRENST00000358808ENST00000392442CLIP1chr12

122812494

-RSRC2chr12

122992997

-
5CDS-5UTRENST00000358808ENST00000392442CLIP1chr12

122825300

-RSRC2chr12

122992994

-
5CDS-5UTRENST00000361654ENST00000392442CLIP1chr12

122812494

-RSRC2chr12

122992997

-
5CDS-5UTRENST00000537178ENST00000392442CLIP1chr12

122812494

-RSRC2chr12

122992997

-
5CDS-5UTRENST00000537178ENST00000392442CLIP1chr12

122825300

-RSRC2chr12

122992994

-
5CDS-5UTRENST00000540338ENST00000392442CLIP1chr12

122812494

-RSRC2chr12

122992997

-
5CDS-5UTRENST00000540338ENST00000392442CLIP1chr12

122825300

-RSRC2chr12

122992994

-
5CDS-5UTRENST00000545889ENST00000392442CLIP1chr12

122812494

-RSRC2chr12

122992997

-
5UTR-3CDSENST00000358808ENST00000331738CLIP1chr12

122907068

-RSRC2chr12

122999774

-
5UTR-3CDSENST00000358808ENST00000331738CLIP1chr12

122907067

-RSRC2chr12

122999774

-
5UTR-3CDSENST00000358808ENST00000331738CLIP1chr12

122907068

-RSRC2chr12

122992994

-
5UTR-3CDSENST00000358808ENST00000331738CLIP1chr12

122907067

-RSRC2chr12

122992994

-
5UTR-3CDSENST00000358808ENST00000354654CLIP1chr12

122907068

-RSRC2chr12

122999774

-
5UTR-3CDSENST00000358808ENST00000354654CLIP1chr12

122907067

-RSRC2chr12

122999774

-
5UTR-3CDSENST00000358808ENST00000354654CLIP1chr12

122907068

-RSRC2chr12

122992994

-
5UTR-3CDSENST00000358808ENST00000354654CLIP1chr12

122907067

-RSRC2chr12

122992994

-
5UTR-3CDSENST00000361654ENST00000331738CLIP1chr12

122907068

-RSRC2chr12

122999774

-
5UTR-3CDSENST00000361654ENST00000331738CLIP1chr12

122907067

-RSRC2chr12

122999774

-
5UTR-3CDSENST00000361654ENST00000331738CLIP1chr12

122907068

-RSRC2chr12

122992994

-
5UTR-3CDSENST00000361654ENST00000331738CLIP1chr12

122907067

-RSRC2chr12

122992994

-
5UTR-3CDSENST00000361654ENST00000354654CLIP1chr12

122907068

-RSRC2chr12

122999774

-
5UTR-3CDSENST00000361654ENST00000354654CLIP1chr12

122907067

-RSRC2chr12

122999774

-
5UTR-3CDSENST00000361654ENST00000354654CLIP1chr12

122907068

-RSRC2chr12

122992994

-
5UTR-3CDSENST00000361654ENST00000354654CLIP1chr12

122907067

-RSRC2chr12

122992994

-
5UTR-3CDSENST00000537178ENST00000331738CLIP1chr12

122907068

-RSRC2chr12

122999774

-
5UTR-3CDSENST00000537178ENST00000331738CLIP1chr12

122907067

-RSRC2chr12

122999774

-
5UTR-3CDSENST00000537178ENST00000331738CLIP1chr12

122907068

-RSRC2chr12

122992994

-
5UTR-3CDSENST00000537178ENST00000331738CLIP1chr12

122907067

-RSRC2chr12

122992994

-
5UTR-3CDSENST00000537178ENST00000354654CLIP1chr12

122907068

-RSRC2chr12

122999774

-
5UTR-3CDSENST00000537178ENST00000354654CLIP1chr12

122907067

-RSRC2chr12

122999774

-
5UTR-3CDSENST00000537178ENST00000354654CLIP1chr12

122907068

-RSRC2chr12

122992994

-
5UTR-3CDSENST00000537178ENST00000354654CLIP1chr12

122907067

-RSRC2chr12

122992994

-
5UTR-5UTRENST00000358808ENST00000392442CLIP1chr12

122907068

-RSRC2chr12

122992994

-
5UTR-5UTRENST00000358808ENST00000392442CLIP1chr12

122907067

-RSRC2chr12

122992994

-
5UTR-5UTRENST00000361654ENST00000392442CLIP1chr12

122907068

-RSRC2chr12

122992994

-
5UTR-5UTRENST00000361654ENST00000392442CLIP1chr12

122907067

-RSRC2chr12

122992994

-
5UTR-5UTRENST00000537178ENST00000392442CLIP1chr12

122907068

-RSRC2chr12

122992994

-
5UTR-5UTRENST00000537178ENST00000392442CLIP1chr12

122907067

-RSRC2chr12

122992994

-
5UTR-intronENST00000358808ENST00000392442CLIP1chr12

122907068

-RSRC2chr12

122999774

-
5UTR-intronENST00000358808ENST00000392442CLIP1chr12

122907067

-RSRC2chr12

122999774

-
5UTR-intronENST00000361654ENST00000392442CLIP1chr12

122907068

-RSRC2chr12

122999774

-
5UTR-intronENST00000361654ENST00000392442CLIP1chr12

122907067

-RSRC2chr12

122999774

-
5UTR-intronENST00000537178ENST00000392442CLIP1chr12

122907068

-RSRC2chr12

122999774

-
5UTR-intronENST00000537178ENST00000392442CLIP1chr12

122907067

-RSRC2chr12

122999774

-
Frame-shiftENST00000302528ENST00000331738CLIP1chr12

122812494

-RSRC2chr12

122992997

-
Frame-shiftENST00000302528ENST00000331738CLIP1chr12

122825300

-RSRC2chr12

122992994

-
Frame-shiftENST00000302528ENST00000354654CLIP1chr12

122812494

-RSRC2chr12

122992997

-
Frame-shiftENST00000302528ENST00000354654CLIP1chr12

122825300

-RSRC2chr12

122992994

-
Frame-shiftENST00000358808ENST00000331738CLIP1chr12

122812494

-RSRC2chr12

122992997

-
Frame-shiftENST00000358808ENST00000331738CLIP1chr12

122825300

-RSRC2chr12

122992994

-
Frame-shiftENST00000358808ENST00000354654CLIP1chr12

122812494

-RSRC2chr12

122992997

-
Frame-shiftENST00000358808ENST00000354654CLIP1chr12

122825300

-RSRC2chr12

122992994

-
Frame-shiftENST00000361654ENST00000331738CLIP1chr12

122812494

-RSRC2chr12

122992997

-
Frame-shiftENST00000361654ENST00000354654CLIP1chr12

122812494

-RSRC2chr12

122992997

-
Frame-shiftENST00000537178ENST00000331738CLIP1chr12

122812494

-RSRC2chr12

122992997

-
Frame-shiftENST00000537178ENST00000331738CLIP1chr12

122825300

-RSRC2chr12

122992994

-
Frame-shiftENST00000537178ENST00000354654CLIP1chr12

122812494

-RSRC2chr12

122992997

-
Frame-shiftENST00000537178ENST00000354654CLIP1chr12

122825300

-RSRC2chr12

122992994

-
Frame-shiftENST00000540338ENST00000331738CLIP1chr12

122812494

-RSRC2chr12

122992997

-
Frame-shiftENST00000540338ENST00000331738CLIP1chr12

122825300

-RSRC2chr12

122992994

-
Frame-shiftENST00000540338ENST00000354654CLIP1chr12

122812494

-RSRC2chr12

122992997

-
Frame-shiftENST00000540338ENST00000354654CLIP1chr12

122825300

-RSRC2chr12

122992994

-
In-frameENST00000545889ENST00000331738CLIP1chr12

122812494

-RSRC2chr12

122992997

-
In-frameENST00000545889ENST00000354654CLIP1chr12

122812494

-RSRC2chr12

122992997

-
intron-3CDSENST00000302528ENST00000331738CLIP1chr12

122884328

-RSRC2chr12

122999774

-
intron-3CDSENST00000302528ENST00000331738CLIP1chr12

122907068

-RSRC2chr12

122999774

-
intron-3CDSENST00000302528ENST00000331738CLIP1chr12

122907067

-RSRC2chr12

122999774

-
intron-3CDSENST00000302528ENST00000331738CLIP1chr12

122907068

-RSRC2chr12

122992994

-
intron-3CDSENST00000302528ENST00000331738CLIP1chr12

122907067

-RSRC2chr12

122992994

-
intron-3CDSENST00000302528ENST00000354654CLIP1chr12

122884328

-RSRC2chr12

122999774

-
intron-3CDSENST00000302528ENST00000354654CLIP1chr12

122907068

-RSRC2chr12

122999774

-
intron-3CDSENST00000302528ENST00000354654CLIP1chr12

122907067

-RSRC2chr12

122999774

-
intron-3CDSENST00000302528ENST00000354654CLIP1chr12

122907068

-RSRC2chr12

122992994

-
intron-3CDSENST00000302528ENST00000354654CLIP1chr12

122907067

-RSRC2chr12

122992994

-
intron-3CDSENST00000358808ENST00000331738CLIP1chr12

122884328

-RSRC2chr12

122999774

-
intron-3CDSENST00000358808ENST00000354654CLIP1chr12

122884328

-RSRC2chr12

122999774

-
intron-3CDSENST00000361654ENST00000331738CLIP1chr12

122884328

-RSRC2chr12

122999774

-
intron-3CDSENST00000361654ENST00000331738CLIP1chr12

122825300

-RSRC2chr12

122992994

-
intron-3CDSENST00000361654ENST00000354654CLIP1chr12

122884328

-RSRC2chr12

122999774

-
intron-3CDSENST00000361654ENST00000354654CLIP1chr12

122825300

-RSRC2chr12

122992994

-
intron-3CDSENST00000536634ENST00000331738CLIP1chr12

122812494

-RSRC2chr12

122992997

-
intron-3CDSENST00000536634ENST00000331738CLIP1chr12

122884328

-RSRC2chr12

122999774

-
intron-3CDSENST00000536634ENST00000331738CLIP1chr12

122907068

-RSRC2chr12

122999774

-
intron-3CDSENST00000536634ENST00000331738CLIP1chr12

122907067

-RSRC2chr12

122999774

-
intron-3CDSENST00000536634ENST00000331738CLIP1chr12

122825300

-RSRC2chr12

122992994

-
intron-3CDSENST00000536634ENST00000331738CLIP1chr12

122907068

-RSRC2chr12

122992994

-
intron-3CDSENST00000536634ENST00000331738CLIP1chr12

122907067

-RSRC2chr12

122992994

-
intron-3CDSENST00000536634ENST00000354654CLIP1chr12

122812494

-RSRC2chr12

122992997

-
intron-3CDSENST00000536634ENST00000354654CLIP1chr12

122884328

-RSRC2chr12

122999774

-
intron-3CDSENST00000536634ENST00000354654CLIP1chr12

122907068

-RSRC2chr12

122999774

-
intron-3CDSENST00000536634ENST00000354654CLIP1chr12

122907067

-RSRC2chr12

122999774

-
intron-3CDSENST00000536634ENST00000354654CLIP1chr12

122825300

-RSRC2chr12

122992994

-
intron-3CDSENST00000536634ENST00000354654CLIP1chr12

122907068

-RSRC2chr12

122992994

-
intron-3CDSENST00000536634ENST00000354654CLIP1chr12

122907067

-RSRC2chr12

122992994

-
intron-3CDSENST00000537178ENST00000331738CLIP1chr12

122884328

-RSRC2chr12

122999774

-
intron-3CDSENST00000537178ENST00000354654CLIP1chr12

122884328

-RSRC2chr12

122999774

-
intron-3CDSENST00000540338ENST00000331738CLIP1chr12

122884328

-RSRC2chr12

122999774

-
intron-3CDSENST00000540338ENST00000331738CLIP1chr12

122907068

-RSRC2chr12

122999774

-
intron-3CDSENST00000540338ENST00000331738CLIP1chr12

122907067

-RSRC2chr12

122999774

-
intron-3CDSENST00000540338ENST00000331738CLIP1chr12

122907068

-RSRC2chr12

122992994

-
intron-3CDSENST00000540338ENST00000331738CLIP1chr12

122907067

-RSRC2chr12

122992994

-
intron-3CDSENST00000540338ENST00000354654CLIP1chr12

122884328

-RSRC2chr12

122999774

-
intron-3CDSENST00000540338ENST00000354654CLIP1chr12

122907068

-RSRC2chr12

122999774

-
intron-3CDSENST00000540338ENST00000354654CLIP1chr12

122907067

-RSRC2chr12

122999774

-
intron-3CDSENST00000540338ENST00000354654CLIP1chr12

122907068

-RSRC2chr12

122992994

-
intron-3CDSENST00000540338ENST00000354654CLIP1chr12

122907067

-RSRC2chr12

122992994

-
intron-3CDSENST00000540539ENST00000331738CLIP1chr12

122812494

-RSRC2chr12

122992997

-
intron-3CDSENST00000540539ENST00000331738CLIP1chr12

122884328

-RSRC2chr12

122999774

-
intron-3CDSENST00000540539ENST00000331738CLIP1chr12

122907068

-RSRC2chr12

122999774

-
intron-3CDSENST00000540539ENST00000331738CLIP1chr12

122907067

-RSRC2chr12

122999774

-
intron-3CDSENST00000540539ENST00000331738CLIP1chr12

122825300

-RSRC2chr12

122992994

-
intron-3CDSENST00000540539ENST00000331738CLIP1chr12

122907068

-RSRC2chr12

122992994

-
intron-3CDSENST00000540539ENST00000331738CLIP1chr12

122907067

-RSRC2chr12

122992994

-
intron-3CDSENST00000540539ENST00000354654CLIP1chr12

122812494

-RSRC2chr12

122992997

-
intron-3CDSENST00000540539ENST00000354654CLIP1chr12

122884328

-RSRC2chr12

122999774

-
intron-3CDSENST00000540539ENST00000354654CLIP1chr12

122907068

-RSRC2chr12

122999774

-
intron-3CDSENST00000540539ENST00000354654CLIP1chr12

122907067

-RSRC2chr12

122999774

-
intron-3CDSENST00000540539ENST00000354654CLIP1chr12

122825300

-RSRC2chr12

122992994

-
intron-3CDSENST00000540539ENST00000354654CLIP1chr12

122907068

-RSRC2chr12

122992994

-
intron-3CDSENST00000540539ENST00000354654CLIP1chr12

122907067

-RSRC2chr12

122992994

-
intron-3CDSENST00000545889ENST00000331738CLIP1chr12

122884328

-RSRC2chr12

122999774

-
intron-3CDSENST00000545889ENST00000331738CLIP1chr12

122907068

-RSRC2chr12

122999774

-
intron-3CDSENST00000545889ENST00000331738CLIP1chr12

122907067

-RSRC2chr12

122999774

-
intron-3CDSENST00000545889ENST00000331738CLIP1chr12

122825300

-RSRC2chr12

122992994

-
intron-3CDSENST00000545889ENST00000331738CLIP1chr12

122907068

-RSRC2chr12

122992994

-
intron-3CDSENST00000545889ENST00000331738CLIP1chr12

122907067

-RSRC2chr12

122992994

-
intron-3CDSENST00000545889ENST00000354654CLIP1chr12

122884328

-RSRC2chr12

122999774

-
intron-3CDSENST00000545889ENST00000354654CLIP1chr12

122907068

-RSRC2chr12

122999774

-
intron-3CDSENST00000545889ENST00000354654CLIP1chr12

122907067

-RSRC2chr12

122999774

-
intron-3CDSENST00000545889ENST00000354654CLIP1chr12

122825300

-RSRC2chr12

122992994

-
intron-3CDSENST00000545889ENST00000354654CLIP1chr12

122907068

-RSRC2chr12

122992994

-
intron-3CDSENST00000545889ENST00000354654CLIP1chr12

122907067

-RSRC2chr12

122992994

-
intron-5UTRENST00000302528ENST00000392442CLIP1chr12

122907068

-RSRC2chr12

122992994

-
intron-5UTRENST00000302528ENST00000392442CLIP1chr12

122907067

-RSRC2chr12

122992994

-
intron-5UTRENST00000361654ENST00000392442CLIP1chr12

122825300

-RSRC2chr12

122992994

-
intron-5UTRENST00000536634ENST00000392442CLIP1chr12

122812494

-RSRC2chr12

122992997

-
intron-5UTRENST00000536634ENST00000392442CLIP1chr12

122825300

-RSRC2chr12

122992994

-
intron-5UTRENST00000536634ENST00000392442CLIP1chr12

122907068

-RSRC2chr12

122992994

-
intron-5UTRENST00000536634ENST00000392442CLIP1chr12

122907067

-RSRC2chr12

122992994

-
intron-5UTRENST00000540338ENST00000392442CLIP1chr12

122907068

-RSRC2chr12

122992994

-
intron-5UTRENST00000540338ENST00000392442CLIP1chr12

122907067

-RSRC2chr12

122992994

-
intron-5UTRENST00000540539ENST00000392442CLIP1chr12

122812494

-RSRC2chr12

122992997

-
intron-5UTRENST00000540539ENST00000392442CLIP1chr12

122825300

-RSRC2chr12

122992994

-
intron-5UTRENST00000540539ENST00000392442CLIP1chr12

122907068

-RSRC2chr12

122992994

-
intron-5UTRENST00000540539ENST00000392442CLIP1chr12

122907067

-RSRC2chr12

122992994

-
intron-5UTRENST00000545889ENST00000392442CLIP1chr12

122825300

-RSRC2chr12

122992994

-
intron-5UTRENST00000545889ENST00000392442CLIP1chr12

122907068

-RSRC2chr12

122992994

-
intron-5UTRENST00000545889ENST00000392442CLIP1chr12

122907067

-RSRC2chr12

122992994

-
intron-intronENST00000302528ENST00000392442CLIP1chr12

122884328

-RSRC2chr12

122999774

-
intron-intronENST00000302528ENST00000392442CLIP1chr12

122907068

-RSRC2chr12

122999774

-
intron-intronENST00000302528ENST00000392442CLIP1chr12

122907067

-RSRC2chr12

122999774

-
intron-intronENST00000358808ENST00000392442CLIP1chr12

122884328

-RSRC2chr12

122999774

-
intron-intronENST00000361654ENST00000392442CLIP1chr12

122884328

-RSRC2chr12

122999774

-
intron-intronENST00000536634ENST00000392442CLIP1chr12

122884328

-RSRC2chr12

122999774

-
intron-intronENST00000536634ENST00000392442CLIP1chr12

122907068

-RSRC2chr12

122999774

-
intron-intronENST00000536634ENST00000392442CLIP1chr12

122907067

-RSRC2chr12

122999774

-
intron-intronENST00000537178ENST00000392442CLIP1chr12

122884328

-RSRC2chr12

122999774

-
intron-intronENST00000540338ENST00000392442CLIP1chr12

122884328

-RSRC2chr12

122999774

-
intron-intronENST00000540338ENST00000392442CLIP1chr12

122907068

-RSRC2chr12

122999774

-
intron-intronENST00000540338ENST00000392442CLIP1chr12

122907067

-RSRC2chr12

122999774

-
intron-intronENST00000540539ENST00000392442CLIP1chr12

122884328

-RSRC2chr12

122999774

-
intron-intronENST00000540539ENST00000392442CLIP1chr12

122907068

-RSRC2chr12

122999774

-
intron-intronENST00000540539ENST00000392442CLIP1chr12

122907067

-RSRC2chr12

122999774

-
intron-intronENST00000545889ENST00000392442CLIP1chr12

122884328

-RSRC2chr12

122999774

-
intron-intronENST00000545889ENST00000392442CLIP1chr12

122907068

-RSRC2chr12

122999774

-
intron-intronENST00000545889ENST00000392442CLIP1chr12

122907067

-RSRC2chr12

122999774

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)
BP loci
(transcript)
Predicted start
(transcript)
Predicted stop
(transcript)
Seq length
(amino acids)
ENST00000545889CLIP1chr12122812494-ENST00000331738RSRC2chr12122992997-35082124632186707
ENST00000545889CLIP1chr12122812494-ENST00000354654RSRC2chr12122992997-34252124632186707

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000545889ENST00000331738CLIP1chr12122812494-RSRC2chr12122992997-0.0049358580.9950642
ENST00000545889ENST00000354654CLIP1chr12122812494-RSRC2chr12122992997-0.0052208930.9947791

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Fusion Genomic Features for CLIP1-RSRC2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for CLIP1-RSRC2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr12:122825300/chr12:122992994)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
CLIP1

P30622

.
FUNCTION: Binds to the plus end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes microtubule growth and microtubule bundling. Links cytoplasmic vesicles to microtubules and thereby plays an important role in intracellular vesicle trafficking. Plays a role macropinocytosis and endosome trafficking. {ECO:0000269|PubMed:12433698, ECO:0000269|PubMed:17563362, ECO:0000269|PubMed:17889670}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCLIP1chr12:122812494chr12:122992997ENST00000302528-1524143_20410721428.0Compositional biasNote=Ser-rich
HgeneCLIP1chr12:122812494chr12:122992997ENST00000302528-1524304_33110721428.0Compositional biasNote=Ser-rich
HgeneCLIP1chr12:122812494chr12:122992997ENST00000358808-1625143_20410721428.0Compositional biasNote=Ser-rich
HgeneCLIP1chr12:122812494chr12:122992997ENST00000358808-1625304_33110721428.0Compositional biasNote=Ser-rich
HgeneCLIP1chr12:122812494chr12:122992997ENST00000537178-1524143_20410371393.0Compositional biasNote=Ser-rich
HgeneCLIP1chr12:122812494chr12:122992997ENST00000537178-1524304_33110371393.0Compositional biasNote=Ser-rich
HgeneCLIP1chr12:122812494chr12:122992997ENST00000540338-1625143_20410831439.0Compositional biasNote=Ser-rich
HgeneCLIP1chr12:122812494chr12:122992997ENST00000540338-1625304_33110831439.0Compositional biasNote=Ser-rich
HgeneCLIP1chr12:122812494chr12:122992997ENST00000302528-1524232_27410721428.0DomainCAP-Gly 2
HgeneCLIP1chr12:122812494chr12:122992997ENST00000302528-152478_12010721428.0DomainCAP-Gly 1
HgeneCLIP1chr12:122812494chr12:122992997ENST00000358808-1625232_27410721428.0DomainCAP-Gly 2
HgeneCLIP1chr12:122812494chr12:122992997ENST00000358808-162578_12010721428.0DomainCAP-Gly 1
HgeneCLIP1chr12:122812494chr12:122992997ENST00000537178-1524232_27410371393.0DomainCAP-Gly 2
HgeneCLIP1chr12:122812494chr12:122992997ENST00000537178-152478_12010371393.0DomainCAP-Gly 1
HgeneCLIP1chr12:122812494chr12:122992997ENST00000540338-1625232_27410831439.0DomainCAP-Gly 2
HgeneCLIP1chr12:122812494chr12:122992997ENST00000540338-162578_12010831439.0DomainCAP-Gly 1
HgeneCLIP1chr12:122812494chr12:122992997ENST00000302528-152497_10110721428.0RegionImportant for tubulin binding
HgeneCLIP1chr12:122812494chr12:122992997ENST00000358808-162597_10110721428.0RegionImportant for tubulin binding
HgeneCLIP1chr12:122812494chr12:122992997ENST00000537178-152497_10110371393.0RegionImportant for tubulin binding
HgeneCLIP1chr12:122812494chr12:122992997ENST00000540338-162597_10110831439.0RegionImportant for tubulin binding
TgeneRSRC2chr12:122812494chr12:122992997ENST00000354654610230_270220387.0Coiled coilOntology_term=ECO:0000255

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCLIP1chr12:122812494chr12:122992997ENST00000302528-1524350_135310721428.0Coiled coilOntology_term=ECO:0000255
HgeneCLIP1chr12:122812494chr12:122992997ENST00000358808-1625350_135310721428.0Coiled coilOntology_term=ECO:0000255
HgeneCLIP1chr12:122812494chr12:122992997ENST00000537178-1524350_135310371393.0Coiled coilOntology_term=ECO:0000255
HgeneCLIP1chr12:122812494chr12:122992997ENST00000540338-1625350_135310831439.0Coiled coilOntology_term=ECO:0000255
HgeneCLIP1chr12:122812494chr12:122992997ENST00000302528-15241417_143410721428.0Zinc fingerCCHC-type
HgeneCLIP1chr12:122812494chr12:122992997ENST00000358808-16251417_143410721428.0Zinc fingerCCHC-type
HgeneCLIP1chr12:122812494chr12:122992997ENST00000537178-15241417_143410371393.0Zinc fingerCCHC-type
HgeneCLIP1chr12:122812494chr12:122992997ENST00000540338-16251417_143410831439.0Zinc fingerCCHC-type
TgeneRSRC2chr12:122812494chr12:122992997ENST00000331738610230_270268435.0Coiled coilOntology_term=ECO:0000255
TgeneRSRC2chr12:122812494chr12:122992997ENST0000033173861027_200268435.0Compositional biasNote=Ser-rich
TgeneRSRC2chr12:122812494chr12:122992997ENST0000035465461027_200220387.0Compositional biasNote=Ser-rich


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Fusion Gene Sequence for CLIP1-RSRC2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>17165_17165_1_CLIP1-RSRC2_CLIP1_chr12_122812494_ENST00000545889_RSRC2_chr12_122992997_ENST00000331738_length(transcript)=3508nt_BP=2124nt
CTTGGGAAGAATGATGGCGCTGTTGCTGGAACAAGGTATTTTCAGTGTCAACCCAAATATGGCTTGTTCGCTCCTGTCCACAAAGTTACC
AAGATTGGCTTCCCTTCCACTACACCAGCCAAAGCCAAGGCCAACGCAGTGAGGCGAGTGATGGCGACCACGTCCGCCAGCCTGAAGCGC
AGCCCTTCTGCCTCTTCCCTCAGCTCCATGAGCTCAGTGGCCTCCTCTGTGAGCAGCAGGCCCAGTCGGACAGGACTATTGACTGAAACC
TCCTCCCGTTACGCCAGGAAGATCTCCGGTACCACTGCCCTCCAGGAGGCCCTGAAGGAGAAGCAGCAGCACATTGAGCAGCTGCTGGCG
GAACGGGATCTGGAGAGGGCGGAGGTGGCCAAGGCCACGAGCCACGTGGGGGAGATAGAGCAGGAGCTAGCTCTGGCCCGGGACGGACAT
GACCAGCATGTCCTGGAATTGGAAGCCAAAATGGACCAGCTGCGAACAATGGTGGAAGCTGCTGACAGGGAGAAGGTGGAGCTTCTCAAC
CAGCTTGAAGAGGAGAAAAGGAAGGTTGAGGACCTTCAGTTCCGGGTTGAAGAAGAATCAATTACCAAAGGTGATCTTGAGACGCAGACC
AAACTGGAGCATGCCCGCATTAAGGAGCTTGAACAGAGCCTGCTCTTTGAAAAGACCAAAGCTGACAAACTCCAGAGGGAGTTAGAAGAC
ACTAGGGTGGCTACAGTTTCAGAAAAGTCACGTATAATGGAACTGGAGAAAGACCTAGCATTGAGAGTACAGGAAGTAGCTGAGCTCCGA
AGAAGGCTAGAGTCCAATAAGCCTGCTGGGGATGTGGACATGTCACTTTCCCTTTTGCAAGAGATAAGCTCTTTGCAAGAAAAGTTAGAA
GTCACCCGTACTGACCACCAGAGAGAAATAACTTCTCTGAAGGAGCATTTTGGAGCCCGGGAAGAAACTCATCAGAAGGAGATAAAGGCT
CTGTATACCGCCACGGAAAAGCTTTCCAAAGAGAACGAGTCATTGAAAAGCAAGCTGGAGCATGCCAACAAAGAGAACTCAGATGTGATA
GCTCTATGGAAGTCCAAACTGGAGACTGCCATCGCATCCCACCAGCAGGCGATGGAAGAACTGAAGGTATCTTTCAGCAAAGGGCTTGGA
ACAGAGACGGCAGAATTTGCTGAACTAAAAACACAAATAGAGAAAATGAGACTAGATTACCAACACGAAATAGAAAATTTGCAGAATCAA
CAAGACTCTGAACGGGCTGCCCATGCTAAAGAGATGGAAGCCTTGAGGGCTAAACTGATGAAAGTTATTAAAGAAAAGGAAAACAGTCTG
GAAGCCATCAGGTCGAAACTGGACAAAGCAGAAGACCAGCATCTCGTAGAAATGGAAGACACGTTAAACAAATTACAGGAAGCTGAAATA
AAGAAAGAAAAGTTTGCTGAAGCTTCAGAGGAGGCAGTCTCTGTTCAGAGAAGTATGCAAGAAACTGTAAATAAGTTACACCAAAAGGAG
GAACAGTTTAACATGCTGTCTTCTGACTTGGAGAAGCTGAGAGAAAACTTAGCAGATATGGAGGCAAAATTTAGAGAGAAAGATGAGAGA
GAAGAGCAGCTGATAAAGGCAAAGGAAAAACTGGAAAATGACATTGCAGAAATAATGAAGATGTCAGGAGATAACTCTTCTCAGCTGACA
AAAATGAACGATGAATTACGTCTGAAAGAAAGAGATGTAGAAGAATTACAGCTAAAACTTACAAAGGCTAATGAAAATGCAAGTTTTCTG
CAAAAAAGTATTGAGGACATGACTGTCAAAGCTGAACAGAGCCAGCAAGAAGCAGCTAAAAAGCATGAGGAAGAAAAGAAAGAATTGGAG
AGGAAATTGTCGGACCTGGAAAAGAAAATGGAAACAAGCCACAACCAGTGTCAGGAGCTGAAAGCCAGGTATGAGAGAGCCACTTCTGAG
ACAAAAACCAAGCATGAAGAAATCCTACAGAACCTCCAGAAGACGCTGCTGGACACAGAGGACAAGCTGAAGGGCGCACGGGAGGAGAAC
AGTGGCTTGCTGCAGGAGCTGGAGGAGCTGAGAAAGCAAGCCGACAAAGCCAAACTGCAGCTACTGGAGGTTCTGTTCTCAATGTTGCTG
CCCTGTTGGCATCAGGAACACAAGTAACACCTCAGATAGCCATGGCAGCTCAGATGGCAGCCCTGCAAGCTAAAGCTTTGGCAGAGACAG
GAATAGCTGTTCCTAGCTACTATAACCCAGCCGCTGTTAATCCAATGAAATTTGCTGAACAAGAGAAAAAAAGGAAAATGCTTTGGCAGG
GCAAGAAAGAAGGGGACAAATCCCAATCTGCTGAAATATGGGAAAAATTGAATTTTGGAAACAAGGACCAAAATGTCAAATTTAGGAAAT
TGATGGGTATTAAGAGTGAAGATGAAGCTGGATGTAGCTCAGTTGATGAAGAAAGTTACAAGACTCTGAAGCAGCAGGAAGAAGTATTTC
GAAATTTAGATGCTCAGTATGAAATGGCAAGATCACAAACCCACACACAAAGAGGAATGGGTTTGGGTTTCACATCTTCAATGCGAGGAA
TGGATGCAGTTTGAAAATGATCACACTTGTAAAGTTTGGGACTTATAGACTTCTTGTTCTGATGTCACGTCCTTGTTCACCAAACAGCTA
GCACTCTAGCTTGCATGGGTGTTGCATTGACTTTAATTTATTGAAAAATACAAATTTTTGTAAATATCAGATCAGTGATACTGGTGTTAG
TGTTGTAATCAGGTTAAACCCACTTCCATTAAACTTGACAGGACTATAGAAGGATAATATTTTTTAGTTCATGAATTCTACTTTTCAAAT
ATATAAAAGCTGCAGGTGGGGATAAAATCTCATACATGGATTTTTTCGTGTCCGCTGTCTTGTGTACTTTTGTACTTAACCTTGTACAGT
TATTTTCATCTCTTGAAACATGAAAGAAATGTTATGTAGATGTTCTTTAGAAGATCTGGCCATTTGGTACATAATCCAGCACAGATAAGC
TGGGTGGTAATGATAATAAAAATGGTTTTCTCAAAACTGGTGTTAATTTAAGTTACCTGGGATGTTTCTTTGAATTTGTTTTATAGTTTC
TGTAGCATTTGGCAATTGCTGTTAGAAAACACTAGCTAGAAATCCCCTCCCCACCACCCTTTTTAAGGCCAGTTAACTATACTACAGTCA
ATACCGTGGTGAGCAAAAATGTAAAAGGTGGAAGGAGAAAACTTACTAAAATAGTATGTTTTCCTATTATAAGGGACAGACTTGGTATTC
AGTATTTGTCAAATATTACATGTGTTATTCAGGAGATAGATTAATGCATTAAAGGGATGTAAGCACTTTTATTTTAATAAAGTGCCTTAT

>17165_17165_1_CLIP1-RSRC2_CLIP1_chr12_122812494_ENST00000545889_RSRC2_chr12_122992997_ENST00000331738_length(amino acids)=707AA_BP=687
MFAPVHKVTKIGFPSTTPAKAKANAVRRVMATTSASLKRSPSASSLSSMSSVASSVSSRPSRTGLLTETSSRYARKISGTTALQEALKEK
QQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDGHDQHVLELEAKMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESI
TKGDLETQTKLEHARIKELEQSLLFEKTKADKLQRELEDTRVATVSEKSRIMELEKDLALRVQEVAELRRRLESNKPAGDVDMSLSLLQE
ISSLQEKLEVTRTDHQREITSLKEHFGAREETHQKEIKALYTATEKLSKENESLKSKLEHANKENSDVIALWKSKLETAIASHQQAMEEL
KVSFSKGLGTETAEFAELKTQIEKMRLDYQHEIENLQNQQDSERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDT
LNKLQEAEIKKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKM
SGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELK

--------------------------------------------------------------
>17165_17165_2_CLIP1-RSRC2_CLIP1_chr12_122812494_ENST00000545889_RSRC2_chr12_122992997_ENST00000354654_length(transcript)=3425nt_BP=2124nt
CTTGGGAAGAATGATGGCGCTGTTGCTGGAACAAGGTATTTTCAGTGTCAACCCAAATATGGCTTGTTCGCTCCTGTCCACAAAGTTACC
AAGATTGGCTTCCCTTCCACTACACCAGCCAAAGCCAAGGCCAACGCAGTGAGGCGAGTGATGGCGACCACGTCCGCCAGCCTGAAGCGC
AGCCCTTCTGCCTCTTCCCTCAGCTCCATGAGCTCAGTGGCCTCCTCTGTGAGCAGCAGGCCCAGTCGGACAGGACTATTGACTGAAACC
TCCTCCCGTTACGCCAGGAAGATCTCCGGTACCACTGCCCTCCAGGAGGCCCTGAAGGAGAAGCAGCAGCACATTGAGCAGCTGCTGGCG
GAACGGGATCTGGAGAGGGCGGAGGTGGCCAAGGCCACGAGCCACGTGGGGGAGATAGAGCAGGAGCTAGCTCTGGCCCGGGACGGACAT
GACCAGCATGTCCTGGAATTGGAAGCCAAAATGGACCAGCTGCGAACAATGGTGGAAGCTGCTGACAGGGAGAAGGTGGAGCTTCTCAAC
CAGCTTGAAGAGGAGAAAAGGAAGGTTGAGGACCTTCAGTTCCGGGTTGAAGAAGAATCAATTACCAAAGGTGATCTTGAGACGCAGACC
AAACTGGAGCATGCCCGCATTAAGGAGCTTGAACAGAGCCTGCTCTTTGAAAAGACCAAAGCTGACAAACTCCAGAGGGAGTTAGAAGAC
ACTAGGGTGGCTACAGTTTCAGAAAAGTCACGTATAATGGAACTGGAGAAAGACCTAGCATTGAGAGTACAGGAAGTAGCTGAGCTCCGA
AGAAGGCTAGAGTCCAATAAGCCTGCTGGGGATGTGGACATGTCACTTTCCCTTTTGCAAGAGATAAGCTCTTTGCAAGAAAAGTTAGAA
GTCACCCGTACTGACCACCAGAGAGAAATAACTTCTCTGAAGGAGCATTTTGGAGCCCGGGAAGAAACTCATCAGAAGGAGATAAAGGCT
CTGTATACCGCCACGGAAAAGCTTTCCAAAGAGAACGAGTCATTGAAAAGCAAGCTGGAGCATGCCAACAAAGAGAACTCAGATGTGATA
GCTCTATGGAAGTCCAAACTGGAGACTGCCATCGCATCCCACCAGCAGGCGATGGAAGAACTGAAGGTATCTTTCAGCAAAGGGCTTGGA
ACAGAGACGGCAGAATTTGCTGAACTAAAAACACAAATAGAGAAAATGAGACTAGATTACCAACACGAAATAGAAAATTTGCAGAATCAA
CAAGACTCTGAACGGGCTGCCCATGCTAAAGAGATGGAAGCCTTGAGGGCTAAACTGATGAAAGTTATTAAAGAAAAGGAAAACAGTCTG
GAAGCCATCAGGTCGAAACTGGACAAAGCAGAAGACCAGCATCTCGTAGAAATGGAAGACACGTTAAACAAATTACAGGAAGCTGAAATA
AAGAAAGAAAAGTTTGCTGAAGCTTCAGAGGAGGCAGTCTCTGTTCAGAGAAGTATGCAAGAAACTGTAAATAAGTTACACCAAAAGGAG
GAACAGTTTAACATGCTGTCTTCTGACTTGGAGAAGCTGAGAGAAAACTTAGCAGATATGGAGGCAAAATTTAGAGAGAAAGATGAGAGA
GAAGAGCAGCTGATAAAGGCAAAGGAAAAACTGGAAAATGACATTGCAGAAATAATGAAGATGTCAGGAGATAACTCTTCTCAGCTGACA
AAAATGAACGATGAATTACGTCTGAAAGAAAGAGATGTAGAAGAATTACAGCTAAAACTTACAAAGGCTAATGAAAATGCAAGTTTTCTG
CAAAAAAGTATTGAGGACATGACTGTCAAAGCTGAACAGAGCCAGCAAGAAGCAGCTAAAAAGCATGAGGAAGAAAAGAAAGAATTGGAG
AGGAAATTGTCGGACCTGGAAAAGAAAATGGAAACAAGCCACAACCAGTGTCAGGAGCTGAAAGCCAGGTATGAGAGAGCCACTTCTGAG
ACAAAAACCAAGCATGAAGAAATCCTACAGAACCTCCAGAAGACGCTGCTGGACACAGAGGACAAGCTGAAGGGCGCACGGGAGGAGAAC
AGTGGCTTGCTGCAGGAGCTGGAGGAGCTGAGAAAGCAAGCCGACAAAGCCAAACTGCAGCTACTGGAGGTTCTGTTCTCAATGTTGCTG
CCCTGTTGGCATCAGGAACACAAGTAACACCTCAGATAGCCATGGCAGCTCAGATGGCAGCCCTGCAAGCTAAAGCTTTGGCAGAGACAG
GAATAGCTGTTCCTAGCTACTATAACCCAGCCGCTGTTAATCCAATGAAATTTGCTGAACAAGAGAAAAAAAGGAAAATGCTTTGGCAGG
GCAAGAAAGAAGGGGACAAATCCCAATCTGCTGAAATATGGGAAAAATTGAATTTTGGAAACAAGGACCAAAATGTCAAATTTAGGAAAT
TGATGGGTATTAAGAGTGAAGATGAAGCTGGATGTAGCTCAGTTGATGAAGAAAGTTACAAGACTCTGAAGCAGCAGGAAGAAGTATTTC
GAAATTTAGATGCTCAGTATGAAATGGCAAGATCACAAACCCACACACAAAGAGGAATGGGTTTGGGTTTCACATCTTCAATGCGAGGAA
TGGATGCAGTTTGAAAATGATCACACTTGTAAAGTTTGGGACTTATAGACTTCTTGTTCTGATGTCACGTCCTTGTTCACCAAACAGCTA
GCACTCTAGCTTGCATGGGTGTTGCATTGACTTTAATTTATTGAAAAATACAAATTTTTGTAAATATCAGATCAGTGATACTGGTGTTAG
TGTTGTAATCAGGTTAAACCCACTTCCATTAAACTTGACAGGACTATAGAAGGATAATATTTTTTAGTTCATGAATTCTACTTTTCAAAT
ATATAAAAGCTGCAGGTGGGGATAAAATCTCATACATGGATTTTTTCGTGTCCGCTGTCTTGTGTACTTTTGTACTTAACCTTGTACAGT
TATTTTCATCTCTTGAAACATGAAAGAAATGTTATGTAGATGTTCTTTAGAAGATCTGGCCATTTGGTACATAATCCAGCACAGATAAGC
TGGGTGGTAATGATAATAAAAATGGTTTTCTCAAAACTGGTGTTAATTTAAGTTACCTGGGATGTTTCTTTGAATTTGTTTTATAGTTTC
TGTAGCATTTGGCAATTGCTGTTAGAAAACACTAGCTAGAAATCCCCTCCCCACCACCCTTTTTAAGGCCAGTTAACTATACTACAGTCA
ATACCGTGGTGAGCAAAAATGTAAAAGGTGGAAGGAGAAAACTTACTAAAATAGTATGTTTTCCTATTATAAGGGACAGACTTGGTATTC
AGTATTTGTCAAATATTACATGTGTTATTCAGGAGATAGATTAATGCATTAAAGGGATGTAAGCACTTTTATTTTAATAAAGTGCCTTAT

>17165_17165_2_CLIP1-RSRC2_CLIP1_chr12_122812494_ENST00000545889_RSRC2_chr12_122992997_ENST00000354654_length(amino acids)=707AA_BP=687
MFAPVHKVTKIGFPSTTPAKAKANAVRRVMATTSASLKRSPSASSLSSMSSVASSVSSRPSRTGLLTETSSRYARKISGTTALQEALKEK
QQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDGHDQHVLELEAKMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESI
TKGDLETQTKLEHARIKELEQSLLFEKTKADKLQRELEDTRVATVSEKSRIMELEKDLALRVQEVAELRRRLESNKPAGDVDMSLSLLQE
ISSLQEKLEVTRTDHQREITSLKEHFGAREETHQKEIKALYTATEKLSKENESLKSKLEHANKENSDVIALWKSKLETAIASHQQAMEEL
KVSFSKGLGTETAEFAELKTQIEKMRLDYQHEIENLQNQQDSERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDT
LNKLQEAEIKKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKM
SGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELK

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Fusion Gene PPI Analysis for CLIP1-RSRC2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CLIP1-RSRC2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CLIP1-RSRC2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource