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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ATXN2-TRIM37 (FusionGDB2 ID:HG6311TG4591)

Fusion Gene Summary for ATXN2-TRIM37

check button Fusion gene summary
Fusion gene informationFusion gene name: ATXN2-TRIM37
Fusion gene ID: hg6311tg4591
HgeneTgene
Gene symbol

ATXN2

TRIM37

Gene ID

6311

4591

Gene nameataxin 2tripartite motif containing 37
SynonymsATX2|SCA2|TNRC13MUL|POB1|TEF3
Cytomap('ATXN2')('TRIM37')

12q24.12

17q22

Type of geneprotein-codingprotein-coding
Descriptionataxin-2spinocerebellar ataxia type 2 proteintrinucleotide repeat-containing gene 13 proteinE3 ubiquitin-protein ligase TRIM37RING-B-box-coiled-coil proteinRING-type E3 ubiquitin transferase TRIM37mulibrey nanism protein
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000377617, ENST00000389153, 
ENST00000535949, ENST00000542287, 
ENST00000608853, ENST00000549455, 
ENST00000550104, 
Fusion gene scores* DoF score22 X 21 X 8=369616 X 15 X 9=2160
# samples 2518
** MAII scorelog2(25/3696*10)=-3.88596475675397
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(18/2160*10)=-3.58496250072116
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ATXN2 [Title/Abstract] AND TRIM37 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointATXN2(111923075)-TRIM37(57079075), # samples:3
Anticipated loss of major functional domain due to fusion event.ATXN2-TRIM37 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ATXN2-TRIM37 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ATXN2-TRIM37 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
ATXN2-TRIM37 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
ATXN2-TRIM37 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneTRIM37

GO:0000122

negative regulation of transcription by RNA polymerase II

25470042

TgeneTRIM37

GO:0032088

negative regulation of NF-kappaB transcription factor activity

11279055

TgeneTRIM37

GO:0035518

histone H2A monoubiquitination

25470042

TgeneTRIM37

GO:0036353

histone H2A-K119 monoubiquitination

25470042

TgeneTRIM37

GO:0051091

positive regulation of DNA-binding transcription factor activity

23077300

TgeneTRIM37

GO:0051092

positive regulation of NF-kappaB transcription factor activity

23077300

TgeneTRIM37

GO:0051865

protein autoubiquitination

15885686

TgeneTRIM37

GO:0070842

aggresome assembly

15885686


check buttonFusion gene breakpoints across ATXN2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across TRIM37 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4PRADTCGA-G9-6354-01AATXN2chr12

111923075

-TRIM37chr17

57079075

-
ChimerDB4PRADTCGA-G9-6354ATXN2chr12

111923069

-TRIM37chr17

57076820

-
ChimerDB4PRADTCGA-G9-6354ATXN2chr12

111923075

-TRIM37chr17

57079075

-
ChimerDB4PRADTCGA-G9-6354ATXN2chr12

111923075

-TRIM37chr17

57079102

-


Top

Fusion Gene ORF analysis for ATXN2-TRIM37

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000377617ENST00000262294ATXN2chr12

111923075

-TRIM37chr17

57079102

-
5CDS-intronENST00000377617ENST00000376149ATXN2chr12

111923075

-TRIM37chr17

57079075

-
5CDS-intronENST00000377617ENST00000376149ATXN2chr12

111923075

-TRIM37chr17

57079102

-
5CDS-intronENST00000377617ENST00000393065ATXN2chr12

111923075

-TRIM37chr17

57079075

-
5CDS-intronENST00000377617ENST00000393065ATXN2chr12

111923075

-TRIM37chr17

57079102

-
5CDS-intronENST00000377617ENST00000393066ATXN2chr12

111923075

-TRIM37chr17

57079102

-
5CDS-intronENST00000377617ENST00000584889ATXN2chr12

111923075

-TRIM37chr17

57079075

-
5CDS-intronENST00000377617ENST00000584889ATXN2chr12

111923069

-TRIM37chr17

57076820

-
5CDS-intronENST00000377617ENST00000584889ATXN2chr12

111923075

-TRIM37chr17

57079102

-
5CDS-intronENST00000389153ENST00000584889ATXN2chr12

111923069

-TRIM37chr17

57076820

-
5CDS-intronENST00000535949ENST00000262294ATXN2chr12

111923075

-TRIM37chr17

57079102

-
5CDS-intronENST00000535949ENST00000376149ATXN2chr12

111923075

-TRIM37chr17

57079075

-
5CDS-intronENST00000535949ENST00000376149ATXN2chr12

111923075

-TRIM37chr17

57079102

-
5CDS-intronENST00000535949ENST00000393065ATXN2chr12

111923075

-TRIM37chr17

57079075

-
5CDS-intronENST00000535949ENST00000393065ATXN2chr12

111923075

-TRIM37chr17

57079102

-
5CDS-intronENST00000535949ENST00000393066ATXN2chr12

111923075

-TRIM37chr17

57079102

-
5CDS-intronENST00000535949ENST00000584889ATXN2chr12

111923075

-TRIM37chr17

57079075

-
5CDS-intronENST00000535949ENST00000584889ATXN2chr12

111923069

-TRIM37chr17

57076820

-
5CDS-intronENST00000535949ENST00000584889ATXN2chr12

111923075

-TRIM37chr17

57079102

-
5CDS-intronENST00000542287ENST00000262294ATXN2chr12

111923075

-TRIM37chr17

57079102

-
5CDS-intronENST00000542287ENST00000376149ATXN2chr12

111923075

-TRIM37chr17

57079075

-
5CDS-intronENST00000542287ENST00000376149ATXN2chr12

111923075

-TRIM37chr17

57079102

-
5CDS-intronENST00000542287ENST00000393065ATXN2chr12

111923075

-TRIM37chr17

57079075

-
5CDS-intronENST00000542287ENST00000393065ATXN2chr12

111923075

-TRIM37chr17

57079102

-
5CDS-intronENST00000542287ENST00000393066ATXN2chr12

111923075

-TRIM37chr17

57079102

-
5CDS-intronENST00000542287ENST00000584889ATXN2chr12

111923075

-TRIM37chr17

57079075

-
5CDS-intronENST00000542287ENST00000584889ATXN2chr12

111923069

-TRIM37chr17

57076820

-
5CDS-intronENST00000542287ENST00000584889ATXN2chr12

111923075

-TRIM37chr17

57079102

-
5CDS-intronENST00000608853ENST00000262294ATXN2chr12

111923075

-TRIM37chr17

57079102

-
5CDS-intronENST00000608853ENST00000376149ATXN2chr12

111923075

-TRIM37chr17

57079075

-
5CDS-intronENST00000608853ENST00000376149ATXN2chr12

111923075

-TRIM37chr17

57079102

-
5CDS-intronENST00000608853ENST00000393065ATXN2chr12

111923075

-TRIM37chr17

57079075

-
5CDS-intronENST00000608853ENST00000393065ATXN2chr12

111923075

-TRIM37chr17

57079102

-
5CDS-intronENST00000608853ENST00000393066ATXN2chr12

111923075

-TRIM37chr17

57079102

-
5CDS-intronENST00000608853ENST00000584889ATXN2chr12

111923075

-TRIM37chr17

57079075

-
5CDS-intronENST00000608853ENST00000584889ATXN2chr12

111923069

-TRIM37chr17

57076820

-
5CDS-intronENST00000608853ENST00000584889ATXN2chr12

111923075

-TRIM37chr17

57079102

-
Frame-shiftENST00000377617ENST00000376149ATXN2chr12

111923069

-TRIM37chr17

57076820

-
Frame-shiftENST00000389153ENST00000376149ATXN2chr12

111923069

-TRIM37chr17

57076820

-
Frame-shiftENST00000535949ENST00000376149ATXN2chr12

111923069

-TRIM37chr17

57076820

-
Frame-shiftENST00000542287ENST00000262294ATXN2chr12

111923075

-TRIM37chr17

57079075

-
Frame-shiftENST00000542287ENST00000262294ATXN2chr12

111923069

-TRIM37chr17

57076820

-
Frame-shiftENST00000542287ENST00000376149ATXN2chr12

111923069

-TRIM37chr17

57076820

-
Frame-shiftENST00000542287ENST00000393065ATXN2chr12

111923069

-TRIM37chr17

57076820

-
Frame-shiftENST00000542287ENST00000393066ATXN2chr12

111923075

-TRIM37chr17

57079075

-
Frame-shiftENST00000542287ENST00000393066ATXN2chr12

111923069

-TRIM37chr17

57076820

-
Frame-shiftENST00000608853ENST00000376149ATXN2chr12

111923069

-TRIM37chr17

57076820

-
In-frameENST00000377617ENST00000262294ATXN2chr12

111923075

-TRIM37chr17

57079075

-
In-frameENST00000377617ENST00000262294ATXN2chr12

111923069

-TRIM37chr17

57076820

-
In-frameENST00000377617ENST00000393065ATXN2chr12

111923069

-TRIM37chr17

57076820

-
In-frameENST00000377617ENST00000393066ATXN2chr12

111923075

-TRIM37chr17

57079075

-
In-frameENST00000377617ENST00000393066ATXN2chr12

111923069

-TRIM37chr17

57076820

-
In-frameENST00000389153ENST00000262294ATXN2chr12

111923069

-TRIM37chr17

57076820

-
In-frameENST00000389153ENST00000393065ATXN2chr12

111923069

-TRIM37chr17

57076820

-
In-frameENST00000389153ENST00000393066ATXN2chr12

111923069

-TRIM37chr17

57076820

-
In-frameENST00000535949ENST00000262294ATXN2chr12

111923075

-TRIM37chr17

57079075

-
In-frameENST00000535949ENST00000262294ATXN2chr12

111923069

-TRIM37chr17

57076820

-
In-frameENST00000535949ENST00000393065ATXN2chr12

111923069

-TRIM37chr17

57076820

-
In-frameENST00000535949ENST00000393066ATXN2chr12

111923075

-TRIM37chr17

57079075

-
In-frameENST00000535949ENST00000393066ATXN2chr12

111923069

-TRIM37chr17

57076820

-
In-frameENST00000608853ENST00000262294ATXN2chr12

111923075

-TRIM37chr17

57079075

-
In-frameENST00000608853ENST00000262294ATXN2chr12

111923069

-TRIM37chr17

57076820

-
In-frameENST00000608853ENST00000393065ATXN2chr12

111923069

-TRIM37chr17

57076820

-
In-frameENST00000608853ENST00000393066ATXN2chr12

111923075

-TRIM37chr17

57079075

-
In-frameENST00000608853ENST00000393066ATXN2chr12

111923069

-TRIM37chr17

57076820

-
intron-3CDSENST00000389153ENST00000262294ATXN2chr12

111923075

-TRIM37chr17

57079075

-
intron-3CDSENST00000389153ENST00000393066ATXN2chr12

111923075

-TRIM37chr17

57079075

-
intron-3CDSENST00000549455ENST00000262294ATXN2chr12

111923075

-TRIM37chr17

57079075

-
intron-3CDSENST00000549455ENST00000262294ATXN2chr12

111923069

-TRIM37chr17

57076820

-
intron-3CDSENST00000549455ENST00000376149ATXN2chr12

111923069

-TRIM37chr17

57076820

-
intron-3CDSENST00000549455ENST00000393065ATXN2chr12

111923069

-TRIM37chr17

57076820

-
intron-3CDSENST00000549455ENST00000393066ATXN2chr12

111923075

-TRIM37chr17

57079075

-
intron-3CDSENST00000549455ENST00000393066ATXN2chr12

111923069

-TRIM37chr17

57076820

-
intron-3CDSENST00000550104ENST00000262294ATXN2chr12

111923075

-TRIM37chr17

57079075

-
intron-3CDSENST00000550104ENST00000262294ATXN2chr12

111923069

-TRIM37chr17

57076820

-
intron-3CDSENST00000550104ENST00000376149ATXN2chr12

111923069

-TRIM37chr17

57076820

-
intron-3CDSENST00000550104ENST00000393065ATXN2chr12

111923069

-TRIM37chr17

57076820

-
intron-3CDSENST00000550104ENST00000393066ATXN2chr12

111923075

-TRIM37chr17

57079075

-
intron-3CDSENST00000550104ENST00000393066ATXN2chr12

111923069

-TRIM37chr17

57076820

-
intron-intronENST00000389153ENST00000262294ATXN2chr12

111923075

-TRIM37chr17

57079102

-
intron-intronENST00000389153ENST00000376149ATXN2chr12

111923075

-TRIM37chr17

57079075

-
intron-intronENST00000389153ENST00000376149ATXN2chr12

111923075

-TRIM37chr17

57079102

-
intron-intronENST00000389153ENST00000393065ATXN2chr12

111923075

-TRIM37chr17

57079075

-
intron-intronENST00000389153ENST00000393065ATXN2chr12

111923075

-TRIM37chr17

57079102

-
intron-intronENST00000389153ENST00000393066ATXN2chr12

111923075

-TRIM37chr17

57079102

-
intron-intronENST00000389153ENST00000584889ATXN2chr12

111923075

-TRIM37chr17

57079075

-
intron-intronENST00000389153ENST00000584889ATXN2chr12

111923075

-TRIM37chr17

57079102

-
intron-intronENST00000549455ENST00000262294ATXN2chr12

111923075

-TRIM37chr17

57079102

-
intron-intronENST00000549455ENST00000376149ATXN2chr12

111923075

-TRIM37chr17

57079075

-
intron-intronENST00000549455ENST00000376149ATXN2chr12

111923075

-TRIM37chr17

57079102

-
intron-intronENST00000549455ENST00000393065ATXN2chr12

111923075

-TRIM37chr17

57079075

-
intron-intronENST00000549455ENST00000393065ATXN2chr12

111923075

-TRIM37chr17

57079102

-
intron-intronENST00000549455ENST00000393066ATXN2chr12

111923075

-TRIM37chr17

57079102

-
intron-intronENST00000549455ENST00000584889ATXN2chr12

111923075

-TRIM37chr17

57079075

-
intron-intronENST00000549455ENST00000584889ATXN2chr12

111923069

-TRIM37chr17

57076820

-
intron-intronENST00000549455ENST00000584889ATXN2chr12

111923075

-TRIM37chr17

57079102

-
intron-intronENST00000550104ENST00000262294ATXN2chr12

111923075

-TRIM37chr17

57079102

-
intron-intronENST00000550104ENST00000376149ATXN2chr12

111923075

-TRIM37chr17

57079075

-
intron-intronENST00000550104ENST00000376149ATXN2chr12

111923075

-TRIM37chr17

57079102

-
intron-intronENST00000550104ENST00000393065ATXN2chr12

111923075

-TRIM37chr17

57079075

-
intron-intronENST00000550104ENST00000393065ATXN2chr12

111923075

-TRIM37chr17

57079102

-
intron-intronENST00000550104ENST00000393066ATXN2chr12

111923075

-TRIM37chr17

57079102

-
intron-intronENST00000550104ENST00000584889ATXN2chr12

111923075

-TRIM37chr17

57079075

-
intron-intronENST00000550104ENST00000584889ATXN2chr12

111923069

-TRIM37chr17

57076820

-
intron-intronENST00000550104ENST00000584889ATXN2chr12

111923075

-TRIM37chr17

57079102

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000608853ATXN2chr12111923075-ENST00000393066TRIM37chr1757079075-330128342533033926
ENST00000608853ATXN2chr12111923075-ENST00000262294TRIM37chr1757079075-420928342533033926
ENST00000377617ATXN2chr12111923075-ENST00000393066TRIM37chr1757079075-3627316016233591065
ENST00000377617ATXN2chr12111923075-ENST00000262294TRIM37chr1757079075-4535316016233591065
ENST00000535949ATXN2chr12111923075-ENST00000393066TRIM37chr1757079075-272422571262456776
ENST00000535949ATXN2chr12111923075-ENST00000262294TRIM37chr1757079075-363222571262456776
ENST00000389153ATXN2chr12111923069-ENST00000393066TRIM37chr1757076820-26622312312394787
ENST00000389153ATXN2chr12111923069-ENST00000262294TRIM37chr1757076820-35702312312394787
ENST00000389153ATXN2chr12111923069-ENST00000393065TRIM37chr1757076820-27852312312394787
ENST00000608853ATXN2chr12111923069-ENST00000393066TRIM37chr1757076820-318428342532916887
ENST00000608853ATXN2chr12111923069-ENST00000262294TRIM37chr1757076820-409228342532916887
ENST00000608853ATXN2chr12111923069-ENST00000393065TRIM37chr1757076820-330728342532916887
ENST00000377617ATXN2chr12111923069-ENST00000393066TRIM37chr1757076820-3510316016232421026
ENST00000377617ATXN2chr12111923069-ENST00000262294TRIM37chr1757076820-4418316016232421026
ENST00000377617ATXN2chr12111923069-ENST00000393065TRIM37chr1757076820-3633316016232421026
ENST00000535949ATXN2chr12111923069-ENST00000393066TRIM37chr1757076820-260722571262339737
ENST00000535949ATXN2chr12111923069-ENST00000262294TRIM37chr1757076820-351522571262339737
ENST00000535949ATXN2chr12111923069-ENST00000393065TRIM37chr1757076820-273022571262339737

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000608853ENST00000393066ATXN2chr12111923075-TRIM37chr1757079075-0.0038391520.99616086
ENST00000608853ENST00000262294ATXN2chr12111923075-TRIM37chr1757079075-0.001684540.99831545
ENST00000377617ENST00000393066ATXN2chr12111923075-TRIM37chr1757079075-0.0020650470.99793494
ENST00000377617ENST00000262294ATXN2chr12111923075-TRIM37chr1757079075-0.0011262880.99887365
ENST00000535949ENST00000393066ATXN2chr12111923075-TRIM37chr1757079075-0.000637530.9993625
ENST00000535949ENST00000262294ATXN2chr12111923075-TRIM37chr1757079075-0.0002463540.99975365
ENST00000389153ENST00000393066ATXN2chr12111923069-TRIM37chr1757076820-0.0009964630.9990036
ENST00000389153ENST00000262294ATXN2chr12111923069-TRIM37chr1757076820-0.0004390940.9995609
ENST00000389153ENST00000393065ATXN2chr12111923069-TRIM37chr1757076820-0.0009599270.99904007
ENST00000608853ENST00000393066ATXN2chr12111923069-TRIM37chr1757076820-0.0049344040.9950656
ENST00000608853ENST00000262294ATXN2chr12111923069-TRIM37chr1757076820-0.0021811340.9978188
ENST00000608853ENST00000393065ATXN2chr12111923069-TRIM37chr1757076820-0.0051032020.9948968
ENST00000377617ENST00000393066ATXN2chr12111923069-TRIM37chr1757076820-0.0020731680.99792683
ENST00000377617ENST00000262294ATXN2chr12111923069-TRIM37chr1757076820-0.0009647270.99903524
ENST00000377617ENST00000393065ATXN2chr12111923069-TRIM37chr1757076820-0.002042990.997957
ENST00000535949ENST00000393066ATXN2chr12111923069-TRIM37chr1757076820-0.0007055270.9992944
ENST00000535949ENST00000262294ATXN2chr12111923069-TRIM37chr1757076820-0.000252220.9997478
ENST00000535949ENST00000393065ATXN2chr12111923069-TRIM37chr1757076820-0.0006698570.99933016

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Fusion Genomic Features for ATXN2-TRIM37


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for ATXN2-TRIM37


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr12:111923075/chr17:57079075)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneATXN2chr12:111923069chr17:57076820ENST00000377617-1825166_1879991314.0Compositional biasNote=Poly-Gln
HgeneATXN2chr12:111923069chr17:57076820ENST00000377617-1825213_2239991314.0Compositional biasNote=Poly-Ser
HgeneATXN2chr12:111923069chr17:57076820ENST00000377617-182547_1589991314.0Compositional biasNote=Pro-rich
HgeneATXN2chr12:111923069chr17:57076820ENST00000377617-1825551_7349991314.0Compositional biasNote=Pro-rich
HgeneATXN2chr12:111923069chr17:57076820ENST00000377617-182555_649991314.0Compositional biasNote=Poly-Pro
HgeneATXN2chr12:111923075chr17:57079075ENST00000377617-1825166_1879991314.0Compositional biasNote=Poly-Gln
HgeneATXN2chr12:111923075chr17:57079075ENST00000377617-1825213_2239991314.0Compositional biasNote=Poly-Ser
HgeneATXN2chr12:111923075chr17:57079075ENST00000377617-182547_1589991314.0Compositional biasNote=Pro-rich
HgeneATXN2chr12:111923075chr17:57079075ENST00000377617-1825551_7349991314.0Compositional biasNote=Pro-rich
HgeneATXN2chr12:111923075chr17:57079075ENST00000377617-182555_649991314.0Compositional biasNote=Poly-Pro
TgeneTRIM37chr12:111923075chr17:57079075ENST00000376149023132_2340804.0Coiled coilOntology_term=ECO:0000255
TgeneTRIM37chr12:111923075chr17:57079075ENST00000376149023419_4500804.0Coiled coilOntology_term=ECO:0000255
TgeneTRIM37chr12:111923075chr17:57079075ENST00000376149023673_7000804.0Coiled coilOntology_term=ECO:0000255
TgeneTRIM37chr12:111923075chr17:57079075ENST00000376149023534_5400804.0Compositional biasNote=Poly-Ser
TgeneTRIM37chr12:111923075chr17:57079075ENST00000376149023578_5810804.0Compositional biasNote=Poly-Ala
TgeneTRIM37chr12:111923075chr17:57079075ENST00000376149023276_4030804.0DomainMATH
TgeneTRIM37chr12:111923075chr17:57079075ENST0000037614902315_550804.0Zinc fingerRING-type%3B degenerate
TgeneTRIM37chr12:111923075chr17:57079075ENST0000037614902390_1320804.0Zinc fingerB box-type

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneATXN2chr12:111923069chr17:57076820ENST00000377617-1825929_10859991314.0Compositional biasNote=Pro-rich
HgeneATXN2chr12:111923069chr17:57076820ENST00000550104-124166_18701015.3333333333334Compositional biasNote=Poly-Gln
HgeneATXN2chr12:111923069chr17:57076820ENST00000550104-124213_22301015.3333333333334Compositional biasNote=Poly-Ser
HgeneATXN2chr12:111923069chr17:57076820ENST00000550104-12447_15801015.3333333333334Compositional biasNote=Pro-rich
HgeneATXN2chr12:111923069chr17:57076820ENST00000550104-124551_73401015.3333333333334Compositional biasNote=Pro-rich
HgeneATXN2chr12:111923069chr17:57076820ENST00000550104-12455_6401015.3333333333334Compositional biasNote=Poly-Pro
HgeneATXN2chr12:111923069chr17:57076820ENST00000550104-124929_108501015.3333333333334Compositional biasNote=Pro-rich
HgeneATXN2chr12:111923075chr17:57079075ENST00000377617-1825929_10859991314.0Compositional biasNote=Pro-rich
HgeneATXN2chr12:111923075chr17:57079075ENST00000550104-124166_18701015.3333333333334Compositional biasNote=Poly-Gln
HgeneATXN2chr12:111923075chr17:57079075ENST00000550104-124213_22301015.3333333333334Compositional biasNote=Poly-Ser
HgeneATXN2chr12:111923075chr17:57079075ENST00000550104-12447_15801015.3333333333334Compositional biasNote=Pro-rich
HgeneATXN2chr12:111923075chr17:57079075ENST00000550104-124551_73401015.3333333333334Compositional biasNote=Pro-rich
HgeneATXN2chr12:111923075chr17:57079075ENST00000550104-12455_6401015.3333333333334Compositional biasNote=Poly-Pro
HgeneATXN2chr12:111923075chr17:57079075ENST00000550104-124929_108501015.3333333333334Compositional biasNote=Pro-rich
TgeneTRIM37chr12:111923069chr17:57076820ENST000002622942224132_234937965.0Coiled coilOntology_term=ECO:0000255
TgeneTRIM37chr12:111923069chr17:57076820ENST000002622942224419_450937965.0Coiled coilOntology_term=ECO:0000255
TgeneTRIM37chr12:111923069chr17:57076820ENST000002622942224673_700937965.0Coiled coilOntology_term=ECO:0000255
TgeneTRIM37chr12:111923069chr17:57076820ENST000003761492123132_234776804.0Coiled coilOntology_term=ECO:0000255
TgeneTRIM37chr12:111923069chr17:57076820ENST000003761492123419_450776804.0Coiled coilOntology_term=ECO:0000255
TgeneTRIM37chr12:111923069chr17:57076820ENST000003761492123673_700776804.0Coiled coilOntology_term=ECO:0000255
TgeneTRIM37chr12:111923069chr17:57076820ENST000003930662225132_234937965.0Coiled coilOntology_term=ECO:0000255
TgeneTRIM37chr12:111923069chr17:57076820ENST000003930662225419_450937965.0Coiled coilOntology_term=ECO:0000255
TgeneTRIM37chr12:111923069chr17:57076820ENST000003930662225673_700937965.0Coiled coilOntology_term=ECO:0000255
TgeneTRIM37chr12:111923075chr17:57079075ENST000002622942124132_234898965.0Coiled coilOntology_term=ECO:0000255
TgeneTRIM37chr12:111923075chr17:57079075ENST000002622942124419_450898965.0Coiled coilOntology_term=ECO:0000255
TgeneTRIM37chr12:111923075chr17:57079075ENST000002622942124673_700898965.0Coiled coilOntology_term=ECO:0000255
TgeneTRIM37chr12:111923075chr17:57079075ENST000003930662125132_234898965.0Coiled coilOntology_term=ECO:0000255
TgeneTRIM37chr12:111923075chr17:57079075ENST000003930662125419_450898965.0Coiled coilOntology_term=ECO:0000255
TgeneTRIM37chr12:111923075chr17:57079075ENST000003930662125673_700898965.0Coiled coilOntology_term=ECO:0000255
TgeneTRIM37chr12:111923069chr17:57076820ENST000002622942224534_540937965.0Compositional biasNote=Poly-Ser
TgeneTRIM37chr12:111923069chr17:57076820ENST000002622942224578_581937965.0Compositional biasNote=Poly-Ala
TgeneTRIM37chr12:111923069chr17:57076820ENST000003761492123534_540776804.0Compositional biasNote=Poly-Ser
TgeneTRIM37chr12:111923069chr17:57076820ENST000003761492123578_581776804.0Compositional biasNote=Poly-Ala
TgeneTRIM37chr12:111923069chr17:57076820ENST000003930662225534_540937965.0Compositional biasNote=Poly-Ser
TgeneTRIM37chr12:111923069chr17:57076820ENST000003930662225578_581937965.0Compositional biasNote=Poly-Ala
TgeneTRIM37chr12:111923075chr17:57079075ENST000002622942124534_540898965.0Compositional biasNote=Poly-Ser
TgeneTRIM37chr12:111923075chr17:57079075ENST000002622942124578_581898965.0Compositional biasNote=Poly-Ala
TgeneTRIM37chr12:111923075chr17:57079075ENST000003930662125534_540898965.0Compositional biasNote=Poly-Ser
TgeneTRIM37chr12:111923075chr17:57079075ENST000003930662125578_581898965.0Compositional biasNote=Poly-Ala
TgeneTRIM37chr12:111923069chr17:57076820ENST000002622942224276_403937965.0DomainMATH
TgeneTRIM37chr12:111923069chr17:57076820ENST000003761492123276_403776804.0DomainMATH
TgeneTRIM37chr12:111923069chr17:57076820ENST000003930662225276_403937965.0DomainMATH
TgeneTRIM37chr12:111923075chr17:57079075ENST000002622942124276_403898965.0DomainMATH
TgeneTRIM37chr12:111923075chr17:57079075ENST000003930662125276_403898965.0DomainMATH
TgeneTRIM37chr12:111923069chr17:57076820ENST00000262294222415_55937965.0Zinc fingerRING-type%3B degenerate
TgeneTRIM37chr12:111923069chr17:57076820ENST00000262294222490_132937965.0Zinc fingerB box-type
TgeneTRIM37chr12:111923069chr17:57076820ENST00000376149212315_55776804.0Zinc fingerRING-type%3B degenerate
TgeneTRIM37chr12:111923069chr17:57076820ENST00000376149212390_132776804.0Zinc fingerB box-type
TgeneTRIM37chr12:111923069chr17:57076820ENST00000393066222515_55937965.0Zinc fingerRING-type%3B degenerate
TgeneTRIM37chr12:111923069chr17:57076820ENST00000393066222590_132937965.0Zinc fingerB box-type
TgeneTRIM37chr12:111923075chr17:57079075ENST00000262294212415_55898965.0Zinc fingerRING-type%3B degenerate
TgeneTRIM37chr12:111923075chr17:57079075ENST00000262294212490_132898965.0Zinc fingerB box-type
TgeneTRIM37chr12:111923075chr17:57079075ENST00000393066212515_55898965.0Zinc fingerRING-type%3B degenerate
TgeneTRIM37chr12:111923075chr17:57079075ENST00000393066212590_132898965.0Zinc fingerB box-type


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Fusion Gene Sequence for ATXN2-TRIM37


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>8437_8437_1_ATXN2-TRIM37_ATXN2_chr12_111923069_ENST00000377617_TRIM37_chr17_57076820_ENST00000262294_length(transcript)=4418nt_BP=3160nt
ACCCCCGAGAAAGCAACCCAGCGCGCCGCCCGCTCCTCACGTGTCCCTCCCGGCCCCGGGGCCACCTCACGTTCTGCTTCCGTCTGACCC
CTCCGACTTCCGGTAAAGAGTCCCTATCCGCACCTCCGCTCCCACCCGGCGCCTCGGCGCGCCCGCCCTCCGATGCGCTCAGCGGCCGCA
GCTCCTCGGAGTCCCGCGGTGGCCACCGAGTCTCGCCGCTTCGCCGCAGCCAGGTGGCCCGGGTGGCGCTCGCTCCAGCGGCCGGCGCGG
CGGAGCGGGCGGGGCGGCGGTGGCGCGGCCCCGGGACCGTATCCCTCCGCCGCCCCTCCCCCGCCCGGCCCCGGCCCCCCTCCCTCCCGG
CAGAGCTCGCCTCCCTCCGCCTCAGACTGTTTTGGTAGCAACGGCAACGGCGGCGGCGCGTTTCGGCCCGGCTCCCGGCGGCTCCTTGGT
CTCGGCGGGCCTCCCCGCCCCTTCGTCGTCCTCCTTCTCCCCCTCGCCAGCCCGGGCGCCCCTCCGGCCGCGCCAACCCGCGCCTCCCCG
CTCGGCGCCCGCGCGTCCCCGCCGCGTTCCGGCGTCTCCTTGGCGCGCCCGGCTCCCGGCTGTCCCCGCCCGGCGTGCGAGCCGGTGTAT
GGGCCCCTCACCATGTCGCTGAAGCCCCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAACAGCAGCAGCAGCAGCAGCAG
CAGCAGCCGCCGCCCGCGGCTGCCAATGTCCGCAAGCCCGGCGGCAGCGGCCTTCTAGCGTCGCCCGCCGCCGCGCCTTCGCCGTCCTCG
TCCTCGGTCTCCTCGTCCTCGGCCACGGCTCCCTCCTCGGTGGTCGCGGCGACCTCCGGCGGCGGGAGGCCCGGCCTGGGCAGAGGTCGA
AACAGTAACAAAGGACTGCCTCAGTCTACGATTTCTTTTGATGGAATCTATGCAAATATGAGGATGGTTCATATACTTACATCAGTTGTT
GGCTCCAAATGTGAAGTACAAGTGAAAAATGGAGGTATATATGAAGGAGTTTTTAAAACTTACAGTCCGAAGTGTGATTTGGTACTTGAT
GCCGCACATGAGAAAAGTACAGAATCCAGTTCGGGGCCGAAACGTGAAGAAATAATGGAGAGTATTTTGTTCAAATGTTCAGACTTTGTT
GTGGTACAGTTTAAAGATATGGACTCCAGTTATGCAAAAAGAGATGCTTTTACTGACTCTGCTATCAGTGCTAAAGTGAATGGCGAACAC
AAAGAGAAGGACCTGGAGCCCTGGGATGCAGGTGAACTCACAGCCAATGAGGAACTTGAGGCTTTGGAAAATGACGTATCTAATGGATGG
GATCCCAATGATATGTTTCGATATAATGAAGAAAATTATGGTGTAGTGTCTACGTATGATAGCAGTTTATCTTCGTATACAGTGCCCTTA
GAAAGAGATAACTCAGAAGAATTTTTAAAACGGGAAGCAAGGGCAAACCAGTTAGCAGAAGAAATTGAGTCAAGTGCCCAGTACAAAGCT
CGAGTGGCCCTGGAAAATGATGATAGGAGTGAGGAAGAAAAATACACAGCAGTTCAGAGAAATTCCAGTGAACGTGAGGGGCACAGCATA
AACACTAGGGAAAATAAATATATTCCTCCTGGACAAAGAAATAGAGAAGTCATATCCTGGGGAAGTGGGAGACAGAATTCACCGCGTATG
GGCCAGCCTGGATCGGGCTCCATGCCATCAAGATCCACTTCTCACACTTCAGATTTCAACCCGAATTCTGGTTCAGACCAAAGAGTAGTT
AATGGAGGTGTTCCCTGGCCATCGCCTTGCCCATCTCCTTCCTCTCGCCCACCTTCTCGCTACCAGTCAGGTCCCAACTCTCTTCCACCT
CGGGCAGCCACCCCTACACGGCCGCCCTCCAGGCCCCCCTCGCGGCCATCCAGACCCCCGTCTCACCCCTCTGCTCATGGTTCTCCAGCT
CCTGTCTCTACTATGCCTAAACGCATGTCTTCAGAAGGGCCTCCAAGGATGTCCCCAAAGGCCCAGCGACATCCTCGAAATCACAGAGTT
TCTGCTGGGAGGGGTTCCATATCCAGTGGCCTAGAATTTGTATCCCACAACCCACCCAGTGAAGCAGCTACTCCTCCAGTAGCAAGGACC
AGTCCCTCGGGGGGAACGTGGTCATCAGTGGTCAGTGGGGTTCCAAGATTATCCCCTAAAACTCATAGACCCAGGTCTCCCAGACAGAAC
AGTATTGGAAATACCCCCAGTGGGCCAGTTCTTGCTTCTCCCCAAGCTGGTATTATTCCAACTGAAGCTGTTGCCATGCCTATTCCAGCT
GCATCTCCTACGCCTGCTAGTCCTGCATCGAACAGAGCTGTTACCCCTTCTAGTGAGGCTAAAGATTCCAGGCTTCAAGATCAGAGGCAG
AACTCTCCTGCAGGGAATAAAGAAAATATTAAACCCAATGAAACATCACCTAGCTTCTCAAAAGCTGAAAACAAAGGTATATCACCAGTT
GTTTCTGAACATAGAAAACAGATTGATGATTTAAAGAAATTTAAGAATGATTTTAGGTTACAGCCAAGTTCTACTTCTGAATCTATGGAT
CAACTACTAAACAAAAATAGAGAGGGAGAAAAATCAAGAGATTTGATCAAAGACAAAATTGAACCAAGTGCTAAGGATTCTTTCATTGAA
AATAGCAGCAGCAACTGTACCAGTGGCAGCAGCAAGCCGAATAGCCCCAGCATTTCCCCTTCAATACTTAGTAACACGGAGCACAAGAGG
GGACCTGAGGTCACTTCCCAAGGGGTTCAGACTTCCAGCCCAGCATGTAAACAAGAGAAAGACGATAAGGAAGAGAAGAAAGACGCAGCT
GAGCAAGTTAGGAAATCAACATTGAATCCCAATGCAAAGGAGTTCAACCCACGTTCCTTCTCTCAGCCAAAGCCTTCTACTACCCCAACT
TCACCTCGGCCTCAAGCACAACCTAGCCCATCTATGGTGGGTCATCAACAGCCAACTCCAGTTTATACTCAGCCTGTTTGTTTTGCACCA
AATATGATGTATCCAGTCCCAGTGAGCCCAGGCGTGCAACCTTTATACCCAATACCTATGACGCCCATGCCAGTGAATCAAGCCAAGACA
TATAGAGCAGATACACATTCCAGTTTTCCTGATGGTGAACAAATAGGCCCTGAAGATCTCAGCTTCAATACAGATGAAAATAGTGGAAGG
TAATTGCCAAATCAAGAGAACTGACTTGCAAGCTACCTTGACCCTGAATTTTGCTGTAGTTGGTGCTCAAATTTGTCATCAGTCAGATAA
TCAGATTTGGTCTTATTTCTTCATTATCTCGACCTGAAATAGTAATTTGGAAACTGTTGGAAGGTGGCACAGTTTAGTCTAAGACAGCAG
TAGTACATGGGAAAAACAGTATGGGAAGAGTTCTTTGTAATGTAAGGAAATAACAATGTAGTTCTCTATTAATTTAGCAAATTTGTACAT
TCACAAAAGGCAGTTTGTCTACTACAGCAGAAGGCTGGTTAACTGCCAGAAAATGTACCTCCAGGCCCTGCATGCCGTCAGTAACCCGCC
CGGCATTGGTGCTCTACTGTCTTTGGCTAGAGCTTAGTTGTGTTTAAATAATCATCTTTATATTTGGGGTTTTAATTACAGTTCCATTAG
TGCCTGTAGATTAGTGAACAGAAAATTGCTTTGGAAGAGATTCTGCCCTGTAGACACTATGTGAATAACTGAAGTAACACTAGACTGAAT
CTCCTTTTTGGAGTATGTATCTTCTCTCACTTGTTCAAGTACAGGCACACTGTTCAACCGCATGGTATCTTTCTGTTGTGTGACTTCTAC
AAATGTAATTTTAAATGAAATTAAGTTAACATGGATTCATTACGTTCCTGGCCCTGTAGACACGTGTAAGATTATTTAAAATTCTTTCAT
TTTTTTCTGCCTCTTACTATACGACTGTAGTGCAACAAATATTTTAAAGCCCCCTTTTCTTCTTTATTTTCATTAGTTGTACATTGATTT
CAGTGTCAACACATTTAAAGATTCATTCATGTTGCACAGTGGCTTACATGAACGTGAAACTGTGATATAAGGTTTTCTTTCATACTCATA
ATTAGCCCAAAACAGTTGCCAAACTTTGCCATTGTGCTCCTGCATTTGTGTTTGAGCTGCTATATATTTGTGGAAATTACACTGAAAGTT
GACTAAGAGACTATTGAAAAAGCATGAATAATTAAATATACATGTGAGAGACATCTCATCTGCTGTATTTTACTTAGTGAATATTGTTCA
CTCTTCCGTGTCTGATGTCTTGCTGAATGCTGTGACTCATAGTTTACTTTTGTTCAAAATAGTTTGCACTTTTTGTTAATAAAATCAACT

>8437_8437_1_ATXN2-TRIM37_ATXN2_chr12_111923069_ENST00000377617_TRIM37_chr17_57076820_ENST00000262294_length(amino acids)=1026AA_BP=999
MRSAAAAPRSPAVATESRRFAAARWPGWRSLQRPARRSGRGGGGAAPGPYPSAAPPPPGPGPPPSRQSSPPSASDCFGSNGNGGGAFRPG
SRRLLGLGGPPRPFVVLLLPLASPGAPPAAPTRASPLGARASPPRSGVSLARPAPGCPRPACEPVYGPLTMSLKPQQQQQQQQQQQQQQQ
QQQQQQQQPPPAAANVRKPGGSGLLASPAAAPSPSSSSVSSSSATAPSSVVAATSGGGRPGLGRGRNSNKGLPQSTISFDGIYANMRMVH
ILTSVVGSKCEVQVKNGGIYEGVFKTYSPKCDLVLDAAHEKSTESSSGPKREEIMESILFKCSDFVVVQFKDMDSSYAKRDAFTDSAISA
KVNGEHKEKDLEPWDAGELTANEELEALENDVSNGWDPNDMFRYNEENYGVVSTYDSSLSSYTVPLERDNSEEFLKREARANQLAEEIES
SAQYKARVALENDDRSEEEKYTAVQRNSSEREGHSINTRENKYIPPGQRNREVISWGSGRQNSPRMGQPGSGSMPSRSTSHTSDFNPNSG
SDQRVVNGGVPWPSPCPSPSSRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSAHGSPAPVSTMPKRMSSEGPPRMSPKAQRH
PRNHRVSAGRGSISSGLEFVSHNPPSEAATPPVARTSPSGGTWSSVVSGVPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEAV
AMPIPAASPTPASPASNRAVTPSSEAKDSRLQDQRQNSPAGNKENIKPNETSPSFSKAENKGISPVVSEHRKQIDDLKKFKNDFRLQPSS
TSESMDQLLNKNREGEKSRDLIKDKIEPSAKDSFIENSSSNCTSGSSKPNSPSISPSILSNTEHKRGPEVTSQGVQTSSPACKQEKDDKE
EKKDAAEQVRKSTLNPNAKEFNPRSFSQPKPSTTPTSPRPQAQPSPSMVGHQQPTPVYTQPVCFAPNMMYPVPVSPGVQPLYPIPMTPMP

--------------------------------------------------------------
>8437_8437_2_ATXN2-TRIM37_ATXN2_chr12_111923069_ENST00000377617_TRIM37_chr17_57076820_ENST00000393065_length(transcript)=3633nt_BP=3160nt
ACCCCCGAGAAAGCAACCCAGCGCGCCGCCCGCTCCTCACGTGTCCCTCCCGGCCCCGGGGCCACCTCACGTTCTGCTTCCGTCTGACCC
CTCCGACTTCCGGTAAAGAGTCCCTATCCGCACCTCCGCTCCCACCCGGCGCCTCGGCGCGCCCGCCCTCCGATGCGCTCAGCGGCCGCA
GCTCCTCGGAGTCCCGCGGTGGCCACCGAGTCTCGCCGCTTCGCCGCAGCCAGGTGGCCCGGGTGGCGCTCGCTCCAGCGGCCGGCGCGG
CGGAGCGGGCGGGGCGGCGGTGGCGCGGCCCCGGGACCGTATCCCTCCGCCGCCCCTCCCCCGCCCGGCCCCGGCCCCCCTCCCTCCCGG
CAGAGCTCGCCTCCCTCCGCCTCAGACTGTTTTGGTAGCAACGGCAACGGCGGCGGCGCGTTTCGGCCCGGCTCCCGGCGGCTCCTTGGT
CTCGGCGGGCCTCCCCGCCCCTTCGTCGTCCTCCTTCTCCCCCTCGCCAGCCCGGGCGCCCCTCCGGCCGCGCCAACCCGCGCCTCCCCG
CTCGGCGCCCGCGCGTCCCCGCCGCGTTCCGGCGTCTCCTTGGCGCGCCCGGCTCCCGGCTGTCCCCGCCCGGCGTGCGAGCCGGTGTAT
GGGCCCCTCACCATGTCGCTGAAGCCCCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAACAGCAGCAGCAGCAGCAGCAG
CAGCAGCCGCCGCCCGCGGCTGCCAATGTCCGCAAGCCCGGCGGCAGCGGCCTTCTAGCGTCGCCCGCCGCCGCGCCTTCGCCGTCCTCG
TCCTCGGTCTCCTCGTCCTCGGCCACGGCTCCCTCCTCGGTGGTCGCGGCGACCTCCGGCGGCGGGAGGCCCGGCCTGGGCAGAGGTCGA
AACAGTAACAAAGGACTGCCTCAGTCTACGATTTCTTTTGATGGAATCTATGCAAATATGAGGATGGTTCATATACTTACATCAGTTGTT
GGCTCCAAATGTGAAGTACAAGTGAAAAATGGAGGTATATATGAAGGAGTTTTTAAAACTTACAGTCCGAAGTGTGATTTGGTACTTGAT
GCCGCACATGAGAAAAGTACAGAATCCAGTTCGGGGCCGAAACGTGAAGAAATAATGGAGAGTATTTTGTTCAAATGTTCAGACTTTGTT
GTGGTACAGTTTAAAGATATGGACTCCAGTTATGCAAAAAGAGATGCTTTTACTGACTCTGCTATCAGTGCTAAAGTGAATGGCGAACAC
AAAGAGAAGGACCTGGAGCCCTGGGATGCAGGTGAACTCACAGCCAATGAGGAACTTGAGGCTTTGGAAAATGACGTATCTAATGGATGG
GATCCCAATGATATGTTTCGATATAATGAAGAAAATTATGGTGTAGTGTCTACGTATGATAGCAGTTTATCTTCGTATACAGTGCCCTTA
GAAAGAGATAACTCAGAAGAATTTTTAAAACGGGAAGCAAGGGCAAACCAGTTAGCAGAAGAAATTGAGTCAAGTGCCCAGTACAAAGCT
CGAGTGGCCCTGGAAAATGATGATAGGAGTGAGGAAGAAAAATACACAGCAGTTCAGAGAAATTCCAGTGAACGTGAGGGGCACAGCATA
AACACTAGGGAAAATAAATATATTCCTCCTGGACAAAGAAATAGAGAAGTCATATCCTGGGGAAGTGGGAGACAGAATTCACCGCGTATG
GGCCAGCCTGGATCGGGCTCCATGCCATCAAGATCCACTTCTCACACTTCAGATTTCAACCCGAATTCTGGTTCAGACCAAAGAGTAGTT
AATGGAGGTGTTCCCTGGCCATCGCCTTGCCCATCTCCTTCCTCTCGCCCACCTTCTCGCTACCAGTCAGGTCCCAACTCTCTTCCACCT
CGGGCAGCCACCCCTACACGGCCGCCCTCCAGGCCCCCCTCGCGGCCATCCAGACCCCCGTCTCACCCCTCTGCTCATGGTTCTCCAGCT
CCTGTCTCTACTATGCCTAAACGCATGTCTTCAGAAGGGCCTCCAAGGATGTCCCCAAAGGCCCAGCGACATCCTCGAAATCACAGAGTT
TCTGCTGGGAGGGGTTCCATATCCAGTGGCCTAGAATTTGTATCCCACAACCCACCCAGTGAAGCAGCTACTCCTCCAGTAGCAAGGACC
AGTCCCTCGGGGGGAACGTGGTCATCAGTGGTCAGTGGGGTTCCAAGATTATCCCCTAAAACTCATAGACCCAGGTCTCCCAGACAGAAC
AGTATTGGAAATACCCCCAGTGGGCCAGTTCTTGCTTCTCCCCAAGCTGGTATTATTCCAACTGAAGCTGTTGCCATGCCTATTCCAGCT
GCATCTCCTACGCCTGCTAGTCCTGCATCGAACAGAGCTGTTACCCCTTCTAGTGAGGCTAAAGATTCCAGGCTTCAAGATCAGAGGCAG
AACTCTCCTGCAGGGAATAAAGAAAATATTAAACCCAATGAAACATCACCTAGCTTCTCAAAAGCTGAAAACAAAGGTATATCACCAGTT
GTTTCTGAACATAGAAAACAGATTGATGATTTAAAGAAATTTAAGAATGATTTTAGGTTACAGCCAAGTTCTACTTCTGAATCTATGGAT
CAACTACTAAACAAAAATAGAGAGGGAGAAAAATCAAGAGATTTGATCAAAGACAAAATTGAACCAAGTGCTAAGGATTCTTTCATTGAA
AATAGCAGCAGCAACTGTACCAGTGGCAGCAGCAAGCCGAATAGCCCCAGCATTTCCCCTTCAATACTTAGTAACACGGAGCACAAGAGG
GGACCTGAGGTCACTTCCCAAGGGGTTCAGACTTCCAGCCCAGCATGTAAACAAGAGAAAGACGATAAGGAAGAGAAGAAAGACGCAGCT
GAGCAAGTTAGGAAATCAACATTGAATCCCAATGCAAAGGAGTTCAACCCACGTTCCTTCTCTCAGCCAAAGCCTTCTACTACCCCAACT
TCACCTCGGCCTCAAGCACAACCTAGCCCATCTATGGTGGGTCATCAACAGCCAACTCCAGTTTATACTCAGCCTGTTTGTTTTGCACCA
AATATGATGTATCCAGTCCCAGTGAGCCCAGGCGTGCAACCTTTATACCCAATACCTATGACGCCCATGCCAGTGAATCAAGCCAAGACA
TATAGAGCAGATACACATTCCAGTTTTCCTGATGGTGAACAAATAGGCCCTGAAGATCTCAGCTTCAATACAGATGAAAATAGTGGAAGG
TAATTGCCAAATCAAGAGAACTGACTTGCAAGCTACCTTGACCCTGAATTTTGCTGTAGTTGGTGCTCAAATTTGTCATCAGTCAGATAA
TCAGATTTGGTCTTATTTCTTCATTATCTCGACCTGAAATAGTAATTTGGAAACTGTTGGAAGGTGGCACAGTTTAGTCTAAGACAGCAG
TAGTACATGGGAAAAACAGTATGGGAAGAGTTCTTTGTAATGTAAGGAAATAACAATGTAGTTCTCTATTAATTTAGCAAATTTGTACAT
TCACAAAAGGCAGTTTGTCTACTACAGCAGAAGGCTGGTTAACTGCCAGAAAATGTACCTCCAGGCCCTGCATGCCGTCAGTAACCCGCC

>8437_8437_2_ATXN2-TRIM37_ATXN2_chr12_111923069_ENST00000377617_TRIM37_chr17_57076820_ENST00000393065_length(amino acids)=1026AA_BP=999
MRSAAAAPRSPAVATESRRFAAARWPGWRSLQRPARRSGRGGGGAAPGPYPSAAPPPPGPGPPPSRQSSPPSASDCFGSNGNGGGAFRPG
SRRLLGLGGPPRPFVVLLLPLASPGAPPAAPTRASPLGARASPPRSGVSLARPAPGCPRPACEPVYGPLTMSLKPQQQQQQQQQQQQQQQ
QQQQQQQQPPPAAANVRKPGGSGLLASPAAAPSPSSSSVSSSSATAPSSVVAATSGGGRPGLGRGRNSNKGLPQSTISFDGIYANMRMVH
ILTSVVGSKCEVQVKNGGIYEGVFKTYSPKCDLVLDAAHEKSTESSSGPKREEIMESILFKCSDFVVVQFKDMDSSYAKRDAFTDSAISA
KVNGEHKEKDLEPWDAGELTANEELEALENDVSNGWDPNDMFRYNEENYGVVSTYDSSLSSYTVPLERDNSEEFLKREARANQLAEEIES
SAQYKARVALENDDRSEEEKYTAVQRNSSEREGHSINTRENKYIPPGQRNREVISWGSGRQNSPRMGQPGSGSMPSRSTSHTSDFNPNSG
SDQRVVNGGVPWPSPCPSPSSRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSAHGSPAPVSTMPKRMSSEGPPRMSPKAQRH
PRNHRVSAGRGSISSGLEFVSHNPPSEAATPPVARTSPSGGTWSSVVSGVPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEAV
AMPIPAASPTPASPASNRAVTPSSEAKDSRLQDQRQNSPAGNKENIKPNETSPSFSKAENKGISPVVSEHRKQIDDLKKFKNDFRLQPSS
TSESMDQLLNKNREGEKSRDLIKDKIEPSAKDSFIENSSSNCTSGSSKPNSPSISPSILSNTEHKRGPEVTSQGVQTSSPACKQEKDDKE
EKKDAAEQVRKSTLNPNAKEFNPRSFSQPKPSTTPTSPRPQAQPSPSMVGHQQPTPVYTQPVCFAPNMMYPVPVSPGVQPLYPIPMTPMP

--------------------------------------------------------------
>8437_8437_3_ATXN2-TRIM37_ATXN2_chr12_111923069_ENST00000377617_TRIM37_chr17_57076820_ENST00000393066_length(transcript)=3510nt_BP=3160nt
ACCCCCGAGAAAGCAACCCAGCGCGCCGCCCGCTCCTCACGTGTCCCTCCCGGCCCCGGGGCCACCTCACGTTCTGCTTCCGTCTGACCC
CTCCGACTTCCGGTAAAGAGTCCCTATCCGCACCTCCGCTCCCACCCGGCGCCTCGGCGCGCCCGCCCTCCGATGCGCTCAGCGGCCGCA
GCTCCTCGGAGTCCCGCGGTGGCCACCGAGTCTCGCCGCTTCGCCGCAGCCAGGTGGCCCGGGTGGCGCTCGCTCCAGCGGCCGGCGCGG
CGGAGCGGGCGGGGCGGCGGTGGCGCGGCCCCGGGACCGTATCCCTCCGCCGCCCCTCCCCCGCCCGGCCCCGGCCCCCCTCCCTCCCGG
CAGAGCTCGCCTCCCTCCGCCTCAGACTGTTTTGGTAGCAACGGCAACGGCGGCGGCGCGTTTCGGCCCGGCTCCCGGCGGCTCCTTGGT
CTCGGCGGGCCTCCCCGCCCCTTCGTCGTCCTCCTTCTCCCCCTCGCCAGCCCGGGCGCCCCTCCGGCCGCGCCAACCCGCGCCTCCCCG
CTCGGCGCCCGCGCGTCCCCGCCGCGTTCCGGCGTCTCCTTGGCGCGCCCGGCTCCCGGCTGTCCCCGCCCGGCGTGCGAGCCGGTGTAT
GGGCCCCTCACCATGTCGCTGAAGCCCCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAACAGCAGCAGCAGCAGCAGCAG
CAGCAGCCGCCGCCCGCGGCTGCCAATGTCCGCAAGCCCGGCGGCAGCGGCCTTCTAGCGTCGCCCGCCGCCGCGCCTTCGCCGTCCTCG
TCCTCGGTCTCCTCGTCCTCGGCCACGGCTCCCTCCTCGGTGGTCGCGGCGACCTCCGGCGGCGGGAGGCCCGGCCTGGGCAGAGGTCGA
AACAGTAACAAAGGACTGCCTCAGTCTACGATTTCTTTTGATGGAATCTATGCAAATATGAGGATGGTTCATATACTTACATCAGTTGTT
GGCTCCAAATGTGAAGTACAAGTGAAAAATGGAGGTATATATGAAGGAGTTTTTAAAACTTACAGTCCGAAGTGTGATTTGGTACTTGAT
GCCGCACATGAGAAAAGTACAGAATCCAGTTCGGGGCCGAAACGTGAAGAAATAATGGAGAGTATTTTGTTCAAATGTTCAGACTTTGTT
GTGGTACAGTTTAAAGATATGGACTCCAGTTATGCAAAAAGAGATGCTTTTACTGACTCTGCTATCAGTGCTAAAGTGAATGGCGAACAC
AAAGAGAAGGACCTGGAGCCCTGGGATGCAGGTGAACTCACAGCCAATGAGGAACTTGAGGCTTTGGAAAATGACGTATCTAATGGATGG
GATCCCAATGATATGTTTCGATATAATGAAGAAAATTATGGTGTAGTGTCTACGTATGATAGCAGTTTATCTTCGTATACAGTGCCCTTA
GAAAGAGATAACTCAGAAGAATTTTTAAAACGGGAAGCAAGGGCAAACCAGTTAGCAGAAGAAATTGAGTCAAGTGCCCAGTACAAAGCT
CGAGTGGCCCTGGAAAATGATGATAGGAGTGAGGAAGAAAAATACACAGCAGTTCAGAGAAATTCCAGTGAACGTGAGGGGCACAGCATA
AACACTAGGGAAAATAAATATATTCCTCCTGGACAAAGAAATAGAGAAGTCATATCCTGGGGAAGTGGGAGACAGAATTCACCGCGTATG
GGCCAGCCTGGATCGGGCTCCATGCCATCAAGATCCACTTCTCACACTTCAGATTTCAACCCGAATTCTGGTTCAGACCAAAGAGTAGTT
AATGGAGGTGTTCCCTGGCCATCGCCTTGCCCATCTCCTTCCTCTCGCCCACCTTCTCGCTACCAGTCAGGTCCCAACTCTCTTCCACCT
CGGGCAGCCACCCCTACACGGCCGCCCTCCAGGCCCCCCTCGCGGCCATCCAGACCCCCGTCTCACCCCTCTGCTCATGGTTCTCCAGCT
CCTGTCTCTACTATGCCTAAACGCATGTCTTCAGAAGGGCCTCCAAGGATGTCCCCAAAGGCCCAGCGACATCCTCGAAATCACAGAGTT
TCTGCTGGGAGGGGTTCCATATCCAGTGGCCTAGAATTTGTATCCCACAACCCACCCAGTGAAGCAGCTACTCCTCCAGTAGCAAGGACC
AGTCCCTCGGGGGGAACGTGGTCATCAGTGGTCAGTGGGGTTCCAAGATTATCCCCTAAAACTCATAGACCCAGGTCTCCCAGACAGAAC
AGTATTGGAAATACCCCCAGTGGGCCAGTTCTTGCTTCTCCCCAAGCTGGTATTATTCCAACTGAAGCTGTTGCCATGCCTATTCCAGCT
GCATCTCCTACGCCTGCTAGTCCTGCATCGAACAGAGCTGTTACCCCTTCTAGTGAGGCTAAAGATTCCAGGCTTCAAGATCAGAGGCAG
AACTCTCCTGCAGGGAATAAAGAAAATATTAAACCCAATGAAACATCACCTAGCTTCTCAAAAGCTGAAAACAAAGGTATATCACCAGTT
GTTTCTGAACATAGAAAACAGATTGATGATTTAAAGAAATTTAAGAATGATTTTAGGTTACAGCCAAGTTCTACTTCTGAATCTATGGAT
CAACTACTAAACAAAAATAGAGAGGGAGAAAAATCAAGAGATTTGATCAAAGACAAAATTGAACCAAGTGCTAAGGATTCTTTCATTGAA
AATAGCAGCAGCAACTGTACCAGTGGCAGCAGCAAGCCGAATAGCCCCAGCATTTCCCCTTCAATACTTAGTAACACGGAGCACAAGAGG
GGACCTGAGGTCACTTCCCAAGGGGTTCAGACTTCCAGCCCAGCATGTAAACAAGAGAAAGACGATAAGGAAGAGAAGAAAGACGCAGCT
GAGCAAGTTAGGAAATCAACATTGAATCCCAATGCAAAGGAGTTCAACCCACGTTCCTTCTCTCAGCCAAAGCCTTCTACTACCCCAACT
TCACCTCGGCCTCAAGCACAACCTAGCCCATCTATGGTGGGTCATCAACAGCCAACTCCAGTTTATACTCAGCCTGTTTGTTTTGCACCA
AATATGATGTATCCAGTCCCAGTGAGCCCAGGCGTGCAACCTTTATACCCAATACCTATGACGCCCATGCCAGTGAATCAAGCCAAGACA
TATAGAGCAGATACACATTCCAGTTTTCCTGATGGTGAACAAATAGGCCCTGAAGATCTCAGCTTCAATACAGATGAAAATAGTGGAAGA
TAATTTGATTTGAAACTGACACTGCACCTGATGGGTTAACAAGATCTAGGCTTCAGAAGGTGACAGATATGAGTGAGGACCATGTGTGGG
GCAAAGCCTCAGAATGATGAAAAGGTTCCGGCACTATAGTTGGGGCCATGTTGACTCCTTTTCAACCATTTGTCACAGACGTGAGAAGAA
GAAATGACTTCAAAATCAAGAGAAAACAAATACTGAAAGTCTCTACTTACATCCAAATTTTAAAAAATAAAATCTGTAGATTAACAATCT

>8437_8437_3_ATXN2-TRIM37_ATXN2_chr12_111923069_ENST00000377617_TRIM37_chr17_57076820_ENST00000393066_length(amino acids)=1026AA_BP=999
MRSAAAAPRSPAVATESRRFAAARWPGWRSLQRPARRSGRGGGGAAPGPYPSAAPPPPGPGPPPSRQSSPPSASDCFGSNGNGGGAFRPG
SRRLLGLGGPPRPFVVLLLPLASPGAPPAAPTRASPLGARASPPRSGVSLARPAPGCPRPACEPVYGPLTMSLKPQQQQQQQQQQQQQQQ
QQQQQQQQPPPAAANVRKPGGSGLLASPAAAPSPSSSSVSSSSATAPSSVVAATSGGGRPGLGRGRNSNKGLPQSTISFDGIYANMRMVH
ILTSVVGSKCEVQVKNGGIYEGVFKTYSPKCDLVLDAAHEKSTESSSGPKREEIMESILFKCSDFVVVQFKDMDSSYAKRDAFTDSAISA
KVNGEHKEKDLEPWDAGELTANEELEALENDVSNGWDPNDMFRYNEENYGVVSTYDSSLSSYTVPLERDNSEEFLKREARANQLAEEIES
SAQYKARVALENDDRSEEEKYTAVQRNSSEREGHSINTRENKYIPPGQRNREVISWGSGRQNSPRMGQPGSGSMPSRSTSHTSDFNPNSG
SDQRVVNGGVPWPSPCPSPSSRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSAHGSPAPVSTMPKRMSSEGPPRMSPKAQRH
PRNHRVSAGRGSISSGLEFVSHNPPSEAATPPVARTSPSGGTWSSVVSGVPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEAV
AMPIPAASPTPASPASNRAVTPSSEAKDSRLQDQRQNSPAGNKENIKPNETSPSFSKAENKGISPVVSEHRKQIDDLKKFKNDFRLQPSS
TSESMDQLLNKNREGEKSRDLIKDKIEPSAKDSFIENSSSNCTSGSSKPNSPSISPSILSNTEHKRGPEVTSQGVQTSSPACKQEKDDKE
EKKDAAEQVRKSTLNPNAKEFNPRSFSQPKPSTTPTSPRPQAQPSPSMVGHQQPTPVYTQPVCFAPNMMYPVPVSPGVQPLYPIPMTPMP

--------------------------------------------------------------
>8437_8437_4_ATXN2-TRIM37_ATXN2_chr12_111923069_ENST00000389153_TRIM37_chr17_57076820_ENST00000262294_length(transcript)=3570nt_BP=2312nt
CGCGGCGACCTCCGGCGGCGGGAGGCCCGGCCTGGGCAGAGGTCGAAACAGTAACAAAGGACTGCCTCAGTCTACGATTTCTTTTGATGG
AATCTATGCAAATATGAGGATGGTTCATATACTTACATCAGTTGTTGGCTCCAAATGTGAAGTACAAGTGAAAAATGGAGGTATATATGA
AGGAGTTTTTAAAACTTACAGTCCGAAGTGTGATTTGGTACTTGATGCCGCACATGAGAAAAGTACAGAATCCAGTTCGGGGCCGAAACG
TGAAGAAATAATGGAGAGTATTTTGTTCAAATGTTCAGACTTTGTTGTGGTACAGTTTAAAGATATGGACTCCAGTTATGCAAAAAGAGA
TGCTTTTACTGACTCTGCTATCAGTGCTAAAGTGAATGGCGAACACAAAGAGAAGGACCTGGAGCCCTGGGATGCAGGTGAACTCACAGC
CAATGAGGAACTTGAGGCTTTGGAAAATGACGTATCTAATGGATGGGATCCCAATGATATGTTTCGATATAATGAAGAAAATTATGGTGT
AGTGTCTACGTATGATAGCAGTTTATCTTCGTATACAGTGCCCTTAGAAAGAGATAACTCAGAAGAATTTTTAAAACGGGAAGCAAGGGC
AAACCAGTTAGCAGAAGAAATTGAGTCAAGTGCCCAGTACAAAGCTCGAGTGGCCCTGGAAAATGATGATAGGAGTGAGGAAGAAAAATA
CACAGCAGTTCAGAGAAATTCCAGTGAACGTGAGGGGCACAGCATAAACACTAGGGAAAATAAATATATTCCTCCTGGACAAAGAAATAG
AGAAGTCATATCCTGGGGAAGTGGGAGACAGAATTCACCGCGTATGGGCCAGCCTGGATCGGGCTCCATGCCATCAAGATCCACTTCTCA
CACTTCAGATTTCAACCCGAATTCTGGTTCAGACCAAAGAGTAGTTAATGGAGGTGTTCCCTGGCCATCGCCTTGCCCATCTCCTTCCTC
TCGCCCACCTTCTCGCTACCAGTCAGGTCCCAACTCTCTTCCACCTCGGGCAGCCACCCCTACACGGCCGCCCTCCAGGCCCCCCTCGCG
GCCATCCAGACCCCCGTCTCACCCCTCTGCTCATGGTTCTCCAGCTCCTGTCTCTACTATGCCTAAACGCATGTCTTCAGAAGGGCCTCC
AAGGATGTCCCCAAAGGCCCAGCGACATCCTCGAAATCACAGAGTTTCTGCTGGGAGGGGTTCCATATCCAGTGGCCTAGAATTTGTATC
CCACAACCCACCCAGTGAAGCAGCTACTCCTCCAGTAGCAAGGACCAGTCCCTCGGGGGGAACGTGGTCATCAGTGGTCAGTGGGGTTCC
AAGATTATCCCCTAAAACTCATAGACCCAGGTCTCCCAGACAGAACAGTATTGGAAATACCCCCAGTGGGCCAGTTCTTGCTTCTCCCCA
AGCTGGTATTATTCCAACTGAAGCTGTTGCCATGCCTATTCCAGCTGCATCTCCTACGCCTGCTAGTCCTGCATCGAACAGAGCTGTTAC
CCCTTCTAGTGAGGCTAAAGATTCCAGGCTTCAAGATCAGAGGCAGAACTCTCCTGCAGGGAATAAAGAAAATATTAAACCCAATGAAAC
ATCACCTAGCTTCTCAAAAGCTGAAAACAAAGGTATATCACCAGTTGTTTCTGAACATAGAAAACAGATTGATGATTTAAAGAAATTTAA
GAATGATTTTAGGTTACAGCCAAGTTCTACTTCTGAATCTATGGATCAACTACTAAACAAAAATAGAGAGGGAGAAAAATCAAGAGATTT
GATCAAAGACAAAATTGAACCAAGTGCTAAGGATTCTTTCATTGAAAATAGCAGCAGCAACTGTACCAGTGGCAGCAGCAAGCCGAATAG
CCCCAGCATTTCCCCTTCAATACTTAGTAACACGGAGCACAAGAGGGGACCTGAGGTCACTTCCCAAGGGGTTCAGACTTCCAGCCCAGC
ATGTAAACAAGAGAAAGACGATAAGGAAGAGAAGAAAGACGCAGCTGAGCAAGTTAGGAAATCAACATTGAATCCCAATGCAAAGGAGTT
CAACCCACGTTCCTTCTCTCAGCCAAAGCCTTCTACTACCCCAACTTCACCTCGGCCTCAAGCACAACCTAGCCCATCTATGGTGGGTCA
TCAACAGCCAACTCCAGTTTATACTCAGCCTGTTTGTTTTGCACCAAATATGATGTATCCAGTCCCAGTGAGCCCAGGCGTGCAACCTTT
ATACCCAATACCTATGACGCCCATGCCAGTGAATCAAGCCAAGACATATAGAGCAGGTAAAGATACACATTCCAGTTTTCCTGATGGTGA
ACAAATAGGCCCTGAAGATCTCAGCTTCAATACAGATGAAAATAGTGGAAGGTAATTGCCAAATCAAGAGAACTGACTTGCAAGCTACCT
TGACCCTGAATTTTGCTGTAGTTGGTGCTCAAATTTGTCATCAGTCAGATAATCAGATTTGGTCTTATTTCTTCATTATCTCGACCTGAA
ATAGTAATTTGGAAACTGTTGGAAGGTGGCACAGTTTAGTCTAAGACAGCAGTAGTACATGGGAAAAACAGTATGGGAAGAGTTCTTTGT
AATGTAAGGAAATAACAATGTAGTTCTCTATTAATTTAGCAAATTTGTACATTCACAAAAGGCAGTTTGTCTACTACAGCAGAAGGCTGG
TTAACTGCCAGAAAATGTACCTCCAGGCCCTGCATGCCGTCAGTAACCCGCCCGGCATTGGTGCTCTACTGTCTTTGGCTAGAGCTTAGT
TGTGTTTAAATAATCATCTTTATATTTGGGGTTTTAATTACAGTTCCATTAGTGCCTGTAGATTAGTGAACAGAAAATTGCTTTGGAAGA
GATTCTGCCCTGTAGACACTATGTGAATAACTGAAGTAACACTAGACTGAATCTCCTTTTTGGAGTATGTATCTTCTCTCACTTGTTCAA
GTACAGGCACACTGTTCAACCGCATGGTATCTTTCTGTTGTGTGACTTCTACAAATGTAATTTTAAATGAAATTAAGTTAACATGGATTC
ATTACGTTCCTGGCCCTGTAGACACGTGTAAGATTATTTAAAATTCTTTCATTTTTTTCTGCCTCTTACTATACGACTGTAGTGCAACAA
ATATTTTAAAGCCCCCTTTTCTTCTTTATTTTCATTAGTTGTACATTGATTTCAGTGTCAACACATTTAAAGATTCATTCATGTTGCACA
GTGGCTTACATGAACGTGAAACTGTGATATAAGGTTTTCTTTCATACTCATAATTAGCCCAAAACAGTTGCCAAACTTTGCCATTGTGCT
CCTGCATTTGTGTTTGAGCTGCTATATATTTGTGGAAATTACACTGAAAGTTGACTAAGAGACTATTGAAAAAGCATGAATAATTAAATA
TACATGTGAGAGACATCTCATCTGCTGTATTTTACTTAGTGAATATTGTTCACTCTTCCGTGTCTGATGTCTTGCTGAATGCTGTGACTC

>8437_8437_4_ATXN2-TRIM37_ATXN2_chr12_111923069_ENST00000389153_TRIM37_chr17_57076820_ENST00000262294_length(amino acids)=787AA_BP=760
MGRGRNSNKGLPQSTISFDGIYANMRMVHILTSVVGSKCEVQVKNGGIYEGVFKTYSPKCDLVLDAAHEKSTESSSGPKREEIMESILFK
CSDFVVVQFKDMDSSYAKRDAFTDSAISAKVNGEHKEKDLEPWDAGELTANEELEALENDVSNGWDPNDMFRYNEENYGVVSTYDSSLSS
YTVPLERDNSEEFLKREARANQLAEEIESSAQYKARVALENDDRSEEEKYTAVQRNSSEREGHSINTRENKYIPPGQRNREVISWGSGRQ
NSPRMGQPGSGSMPSRSTSHTSDFNPNSGSDQRVVNGGVPWPSPCPSPSSRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSA
HGSPAPVSTMPKRMSSEGPPRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAATPPVARTSPSGGTWSSVVSGVPRLSPKTHRPR
SPRQNSIGNTPSGPVLASPQAGIIPTEAVAMPIPAASPTPASPASNRAVTPSSEAKDSRLQDQRQNSPAGNKENIKPNETSPSFSKAENK
GISPVVSEHRKQIDDLKKFKNDFRLQPSSTSESMDQLLNKNREGEKSRDLIKDKIEPSAKDSFIENSSSNCTSGSSKPNSPSISPSILSN
TEHKRGPEVTSQGVQTSSPACKQEKDDKEEKKDAAEQVRKSTLNPNAKEFNPRSFSQPKPSTTPTSPRPQAQPSPSMVGHQQPTPVYTQP

--------------------------------------------------------------
>8437_8437_5_ATXN2-TRIM37_ATXN2_chr12_111923069_ENST00000389153_TRIM37_chr17_57076820_ENST00000393065_length(transcript)=2785nt_BP=2312nt
CGCGGCGACCTCCGGCGGCGGGAGGCCCGGCCTGGGCAGAGGTCGAAACAGTAACAAAGGACTGCCTCAGTCTACGATTTCTTTTGATGG
AATCTATGCAAATATGAGGATGGTTCATATACTTACATCAGTTGTTGGCTCCAAATGTGAAGTACAAGTGAAAAATGGAGGTATATATGA
AGGAGTTTTTAAAACTTACAGTCCGAAGTGTGATTTGGTACTTGATGCCGCACATGAGAAAAGTACAGAATCCAGTTCGGGGCCGAAACG
TGAAGAAATAATGGAGAGTATTTTGTTCAAATGTTCAGACTTTGTTGTGGTACAGTTTAAAGATATGGACTCCAGTTATGCAAAAAGAGA
TGCTTTTACTGACTCTGCTATCAGTGCTAAAGTGAATGGCGAACACAAAGAGAAGGACCTGGAGCCCTGGGATGCAGGTGAACTCACAGC
CAATGAGGAACTTGAGGCTTTGGAAAATGACGTATCTAATGGATGGGATCCCAATGATATGTTTCGATATAATGAAGAAAATTATGGTGT
AGTGTCTACGTATGATAGCAGTTTATCTTCGTATACAGTGCCCTTAGAAAGAGATAACTCAGAAGAATTTTTAAAACGGGAAGCAAGGGC
AAACCAGTTAGCAGAAGAAATTGAGTCAAGTGCCCAGTACAAAGCTCGAGTGGCCCTGGAAAATGATGATAGGAGTGAGGAAGAAAAATA
CACAGCAGTTCAGAGAAATTCCAGTGAACGTGAGGGGCACAGCATAAACACTAGGGAAAATAAATATATTCCTCCTGGACAAAGAAATAG
AGAAGTCATATCCTGGGGAAGTGGGAGACAGAATTCACCGCGTATGGGCCAGCCTGGATCGGGCTCCATGCCATCAAGATCCACTTCTCA
CACTTCAGATTTCAACCCGAATTCTGGTTCAGACCAAAGAGTAGTTAATGGAGGTGTTCCCTGGCCATCGCCTTGCCCATCTCCTTCCTC
TCGCCCACCTTCTCGCTACCAGTCAGGTCCCAACTCTCTTCCACCTCGGGCAGCCACCCCTACACGGCCGCCCTCCAGGCCCCCCTCGCG
GCCATCCAGACCCCCGTCTCACCCCTCTGCTCATGGTTCTCCAGCTCCTGTCTCTACTATGCCTAAACGCATGTCTTCAGAAGGGCCTCC
AAGGATGTCCCCAAAGGCCCAGCGACATCCTCGAAATCACAGAGTTTCTGCTGGGAGGGGTTCCATATCCAGTGGCCTAGAATTTGTATC
CCACAACCCACCCAGTGAAGCAGCTACTCCTCCAGTAGCAAGGACCAGTCCCTCGGGGGGAACGTGGTCATCAGTGGTCAGTGGGGTTCC
AAGATTATCCCCTAAAACTCATAGACCCAGGTCTCCCAGACAGAACAGTATTGGAAATACCCCCAGTGGGCCAGTTCTTGCTTCTCCCCA
AGCTGGTATTATTCCAACTGAAGCTGTTGCCATGCCTATTCCAGCTGCATCTCCTACGCCTGCTAGTCCTGCATCGAACAGAGCTGTTAC
CCCTTCTAGTGAGGCTAAAGATTCCAGGCTTCAAGATCAGAGGCAGAACTCTCCTGCAGGGAATAAAGAAAATATTAAACCCAATGAAAC
ATCACCTAGCTTCTCAAAAGCTGAAAACAAAGGTATATCACCAGTTGTTTCTGAACATAGAAAACAGATTGATGATTTAAAGAAATTTAA
GAATGATTTTAGGTTACAGCCAAGTTCTACTTCTGAATCTATGGATCAACTACTAAACAAAAATAGAGAGGGAGAAAAATCAAGAGATTT
GATCAAAGACAAAATTGAACCAAGTGCTAAGGATTCTTTCATTGAAAATAGCAGCAGCAACTGTACCAGTGGCAGCAGCAAGCCGAATAG
CCCCAGCATTTCCCCTTCAATACTTAGTAACACGGAGCACAAGAGGGGACCTGAGGTCACTTCCCAAGGGGTTCAGACTTCCAGCCCAGC
ATGTAAACAAGAGAAAGACGATAAGGAAGAGAAGAAAGACGCAGCTGAGCAAGTTAGGAAATCAACATTGAATCCCAATGCAAAGGAGTT
CAACCCACGTTCCTTCTCTCAGCCAAAGCCTTCTACTACCCCAACTTCACCTCGGCCTCAAGCACAACCTAGCCCATCTATGGTGGGTCA
TCAACAGCCAACTCCAGTTTATACTCAGCCTGTTTGTTTTGCACCAAATATGATGTATCCAGTCCCAGTGAGCCCAGGCGTGCAACCTTT
ATACCCAATACCTATGACGCCCATGCCAGTGAATCAAGCCAAGACATATAGAGCAGGTAAAGATACACATTCCAGTTTTCCTGATGGTGA
ACAAATAGGCCCTGAAGATCTCAGCTTCAATACAGATGAAAATAGTGGAAGGTAATTGCCAAATCAAGAGAACTGACTTGCAAGCTACCT
TGACCCTGAATTTTGCTGTAGTTGGTGCTCAAATTTGTCATCAGTCAGATAATCAGATTTGGTCTTATTTCTTCATTATCTCGACCTGAA
ATAGTAATTTGGAAACTGTTGGAAGGTGGCACAGTTTAGTCTAAGACAGCAGTAGTACATGGGAAAAACAGTATGGGAAGAGTTCTTTGT
AATGTAAGGAAATAACAATGTAGTTCTCTATTAATTTAGCAAATTTGTACATTCACAAAAGGCAGTTTGTCTACTACAGCAGAAGGCTGG

>8437_8437_5_ATXN2-TRIM37_ATXN2_chr12_111923069_ENST00000389153_TRIM37_chr17_57076820_ENST00000393065_length(amino acids)=787AA_BP=760
MGRGRNSNKGLPQSTISFDGIYANMRMVHILTSVVGSKCEVQVKNGGIYEGVFKTYSPKCDLVLDAAHEKSTESSSGPKREEIMESILFK
CSDFVVVQFKDMDSSYAKRDAFTDSAISAKVNGEHKEKDLEPWDAGELTANEELEALENDVSNGWDPNDMFRYNEENYGVVSTYDSSLSS
YTVPLERDNSEEFLKREARANQLAEEIESSAQYKARVALENDDRSEEEKYTAVQRNSSEREGHSINTRENKYIPPGQRNREVISWGSGRQ
NSPRMGQPGSGSMPSRSTSHTSDFNPNSGSDQRVVNGGVPWPSPCPSPSSRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSA
HGSPAPVSTMPKRMSSEGPPRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAATPPVARTSPSGGTWSSVVSGVPRLSPKTHRPR
SPRQNSIGNTPSGPVLASPQAGIIPTEAVAMPIPAASPTPASPASNRAVTPSSEAKDSRLQDQRQNSPAGNKENIKPNETSPSFSKAENK
GISPVVSEHRKQIDDLKKFKNDFRLQPSSTSESMDQLLNKNREGEKSRDLIKDKIEPSAKDSFIENSSSNCTSGSSKPNSPSISPSILSN
TEHKRGPEVTSQGVQTSSPACKQEKDDKEEKKDAAEQVRKSTLNPNAKEFNPRSFSQPKPSTTPTSPRPQAQPSPSMVGHQQPTPVYTQP

--------------------------------------------------------------
>8437_8437_6_ATXN2-TRIM37_ATXN2_chr12_111923069_ENST00000389153_TRIM37_chr17_57076820_ENST00000393066_length(transcript)=2662nt_BP=2312nt
CGCGGCGACCTCCGGCGGCGGGAGGCCCGGCCTGGGCAGAGGTCGAAACAGTAACAAAGGACTGCCTCAGTCTACGATTTCTTTTGATGG
AATCTATGCAAATATGAGGATGGTTCATATACTTACATCAGTTGTTGGCTCCAAATGTGAAGTACAAGTGAAAAATGGAGGTATATATGA
AGGAGTTTTTAAAACTTACAGTCCGAAGTGTGATTTGGTACTTGATGCCGCACATGAGAAAAGTACAGAATCCAGTTCGGGGCCGAAACG
TGAAGAAATAATGGAGAGTATTTTGTTCAAATGTTCAGACTTTGTTGTGGTACAGTTTAAAGATATGGACTCCAGTTATGCAAAAAGAGA
TGCTTTTACTGACTCTGCTATCAGTGCTAAAGTGAATGGCGAACACAAAGAGAAGGACCTGGAGCCCTGGGATGCAGGTGAACTCACAGC
CAATGAGGAACTTGAGGCTTTGGAAAATGACGTATCTAATGGATGGGATCCCAATGATATGTTTCGATATAATGAAGAAAATTATGGTGT
AGTGTCTACGTATGATAGCAGTTTATCTTCGTATACAGTGCCCTTAGAAAGAGATAACTCAGAAGAATTTTTAAAACGGGAAGCAAGGGC
AAACCAGTTAGCAGAAGAAATTGAGTCAAGTGCCCAGTACAAAGCTCGAGTGGCCCTGGAAAATGATGATAGGAGTGAGGAAGAAAAATA
CACAGCAGTTCAGAGAAATTCCAGTGAACGTGAGGGGCACAGCATAAACACTAGGGAAAATAAATATATTCCTCCTGGACAAAGAAATAG
AGAAGTCATATCCTGGGGAAGTGGGAGACAGAATTCACCGCGTATGGGCCAGCCTGGATCGGGCTCCATGCCATCAAGATCCACTTCTCA
CACTTCAGATTTCAACCCGAATTCTGGTTCAGACCAAAGAGTAGTTAATGGAGGTGTTCCCTGGCCATCGCCTTGCCCATCTCCTTCCTC
TCGCCCACCTTCTCGCTACCAGTCAGGTCCCAACTCTCTTCCACCTCGGGCAGCCACCCCTACACGGCCGCCCTCCAGGCCCCCCTCGCG
GCCATCCAGACCCCCGTCTCACCCCTCTGCTCATGGTTCTCCAGCTCCTGTCTCTACTATGCCTAAACGCATGTCTTCAGAAGGGCCTCC
AAGGATGTCCCCAAAGGCCCAGCGACATCCTCGAAATCACAGAGTTTCTGCTGGGAGGGGTTCCATATCCAGTGGCCTAGAATTTGTATC
CCACAACCCACCCAGTGAAGCAGCTACTCCTCCAGTAGCAAGGACCAGTCCCTCGGGGGGAACGTGGTCATCAGTGGTCAGTGGGGTTCC
AAGATTATCCCCTAAAACTCATAGACCCAGGTCTCCCAGACAGAACAGTATTGGAAATACCCCCAGTGGGCCAGTTCTTGCTTCTCCCCA
AGCTGGTATTATTCCAACTGAAGCTGTTGCCATGCCTATTCCAGCTGCATCTCCTACGCCTGCTAGTCCTGCATCGAACAGAGCTGTTAC
CCCTTCTAGTGAGGCTAAAGATTCCAGGCTTCAAGATCAGAGGCAGAACTCTCCTGCAGGGAATAAAGAAAATATTAAACCCAATGAAAC
ATCACCTAGCTTCTCAAAAGCTGAAAACAAAGGTATATCACCAGTTGTTTCTGAACATAGAAAACAGATTGATGATTTAAAGAAATTTAA
GAATGATTTTAGGTTACAGCCAAGTTCTACTTCTGAATCTATGGATCAACTACTAAACAAAAATAGAGAGGGAGAAAAATCAAGAGATTT
GATCAAAGACAAAATTGAACCAAGTGCTAAGGATTCTTTCATTGAAAATAGCAGCAGCAACTGTACCAGTGGCAGCAGCAAGCCGAATAG
CCCCAGCATTTCCCCTTCAATACTTAGTAACACGGAGCACAAGAGGGGACCTGAGGTCACTTCCCAAGGGGTTCAGACTTCCAGCCCAGC
ATGTAAACAAGAGAAAGACGATAAGGAAGAGAAGAAAGACGCAGCTGAGCAAGTTAGGAAATCAACATTGAATCCCAATGCAAAGGAGTT
CAACCCACGTTCCTTCTCTCAGCCAAAGCCTTCTACTACCCCAACTTCACCTCGGCCTCAAGCACAACCTAGCCCATCTATGGTGGGTCA
TCAACAGCCAACTCCAGTTTATACTCAGCCTGTTTGTTTTGCACCAAATATGATGTATCCAGTCCCAGTGAGCCCAGGCGTGCAACCTTT
ATACCCAATACCTATGACGCCCATGCCAGTGAATCAAGCCAAGACATATAGAGCAGGTAAAGATACACATTCCAGTTTTCCTGATGGTGA
ACAAATAGGCCCTGAAGATCTCAGCTTCAATACAGATGAAAATAGTGGAAGATAATTTGATTTGAAACTGACACTGCACCTGATGGGTTA
ACAAGATCTAGGCTTCAGAAGGTGACAGATATGAGTGAGGACCATGTGTGGGGCAAAGCCTCAGAATGATGAAAAGGTTCCGGCACTATA
GTTGGGGCCATGTTGACTCCTTTTCAACCATTTGTCACAGACGTGAGAAGAAGAAATGACTTCAAAATCAAGAGAAAACAAATACTGAAA

>8437_8437_6_ATXN2-TRIM37_ATXN2_chr12_111923069_ENST00000389153_TRIM37_chr17_57076820_ENST00000393066_length(amino acids)=787AA_BP=760
MGRGRNSNKGLPQSTISFDGIYANMRMVHILTSVVGSKCEVQVKNGGIYEGVFKTYSPKCDLVLDAAHEKSTESSSGPKREEIMESILFK
CSDFVVVQFKDMDSSYAKRDAFTDSAISAKVNGEHKEKDLEPWDAGELTANEELEALENDVSNGWDPNDMFRYNEENYGVVSTYDSSLSS
YTVPLERDNSEEFLKREARANQLAEEIESSAQYKARVALENDDRSEEEKYTAVQRNSSEREGHSINTRENKYIPPGQRNREVISWGSGRQ
NSPRMGQPGSGSMPSRSTSHTSDFNPNSGSDQRVVNGGVPWPSPCPSPSSRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSA
HGSPAPVSTMPKRMSSEGPPRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAATPPVARTSPSGGTWSSVVSGVPRLSPKTHRPR
SPRQNSIGNTPSGPVLASPQAGIIPTEAVAMPIPAASPTPASPASNRAVTPSSEAKDSRLQDQRQNSPAGNKENIKPNETSPSFSKAENK
GISPVVSEHRKQIDDLKKFKNDFRLQPSSTSESMDQLLNKNREGEKSRDLIKDKIEPSAKDSFIENSSSNCTSGSSKPNSPSISPSILSN
TEHKRGPEVTSQGVQTSSPACKQEKDDKEEKKDAAEQVRKSTLNPNAKEFNPRSFSQPKPSTTPTSPRPQAQPSPSMVGHQQPTPVYTQP

--------------------------------------------------------------
>8437_8437_7_ATXN2-TRIM37_ATXN2_chr12_111923069_ENST00000535949_TRIM37_chr17_57076820_ENST00000262294_length(transcript)=3515nt_BP=2257nt
CCCGAGAAAGCAACCCAGCGCGCCGCCCGCTCCTCACGTGTCCCTCCCGGCCCCGGGGCCACCTCACGTTCTGCTTCCGTCTGACCCCTC
CGACTTCCGATTTCTTTTGATGGAATCTATGCAAATATGAGGATGGTTCATATACTTACATCAGTTGTTTGTGATTTGGTACTTGATGCC
GCACATGAGAAAAGTACAGAATCCAGTTCGGGGCCGAAACGTGAAGAAATAATGGAGAGTATTTTGTTCAAATGTTCAGACTTTGTTGTG
GTACAGTTTAAAGATATGGACTCCAGTTATGCAAAAAGAGATGCTTTTACTGACTCTGCTATCAGTGCTAAAGTGAATGGCGAACACAAA
GAGAAGGACCTGGAGCCCTGGGATGCAGGTGAACTCACAGCCAATGAGGAACTTGAGGCTTTGGAAAATGACGTATCTAATGGATGGGAT
CCCAATGATATGTTTCGATATAATGAAGAAAATTATGGTGTAGTGTCTACGTATGATAGCAGTTTATCTTCGTATACAGTGCCCTTAGAA
AGAGATAACTCAGAAGAATTTTTAAAACGGGAAGCAAGGGCAAACCAGTTAGCAGAAGAAATTGAGTCAAGTGCCCAGTACAAAGCTCGA
GTGGCCCTGGAAAATGATGATAGGAGTGAGGAAGAAAAATACACAGCAGTTCAGAGAAATTCCAGTGAACGTGAGGGGCACAGCATAAAC
ACTAGGGAAAATAAATATATTCCTCCTGGACAAAGAAATAGAGAAGTCATATCCTGGGGAAGTGGGAGACAGAATTCACCGCGTATGGGC
CAGCCTGGATCGGGCTCCATGCCATCAAGATCCACTTCTCACACTTCAGATTTCAACCCGAATTCTGGTTCAGACCAAAGAGTAGTTAAT
GGAGGTGTTCCCTGGCCATCGCCTTGCCCATCTCCTTCCTCTCGCCCACCTTCTCGCTACCAGTCAGGTCCCAACTCTCTTCCACCTCGG
GCAGCCACCCCTACACGGCCGCCCTCCAGGCCCCCCTCGCGGCCATCCAGACCCCCGTCTCACCCCTCTGCTCATGGTTCTCCAGCTCCT
GTCTCTACTATGCCTAAACGCATGTCTTCAGAAGGGCCTCCAAGGATGTCCCCAAAGGCCCAGCGACATCCTCGAAATCACAGAGTTTCT
GCTGGGAGGGGTTCCATATCCAGTGGCCTAGAATTTGTATCCCACAACCCACCCAGTGAAGCAGCTACTCCTCCAGTAGCAAGGACCAGT
CCCTCGGGGGGAACGTGGTCATCAGTGGTCAGTGGGGTTCCAAGATTATCCCCTAAAACTCATAGACCCAGGTCTCCCAGACAGAACAGT
ATTGGAAATACCCCCAGTGGGCCAGTTCTTGCTTCTCCCCAAGCTGGTATTATTCCAACTGAAGCTGTTGCCATGCCTATTCCAGCTGCA
TCTCCTACGCCTGCTAGTCCTGCATCGAACAGAGCTGTTACCCCTTCTAGTGAGGCTAAAGATTCCAGGCTTCAAGATCAGAGGCAGAAC
TCTCCTGCAGGGAATAAAGAAAATATTAAACCCAATGAAACATCACCTAGCTTCTCAAAAGCTGAAAACAAAGGTATATCACCAGTTGTT
TCTGAACATAGAAAACAGATTGATGATTTAAAGAAATTTAAGAATGATTTTAGGTTACAGCCAAGTTCTACTTCTGAATCTATGGATCAA
CTACTAAACAAAAATAGAGAGGGAGAAAAATCAAGAGATTTGATCAAAGACAAAATTGAACCAAGTGCTAAGGATTCTTTCATTGAAAAT
AGCAGCAGCAACTGTACCAGTGGCAGCAGCAAGCCGAATAGCCCCAGCATTTCCCCTTCAATACTTAGTAACACGGAGCACAAGAGGGGA
CCTGAGGTCACTTCCCAAGGGGTTCAGACTTCCAGCCCAGCATGTAAACAAGAGAAAGACGATAAGGAAGAGAAGAAAGACGCAGCTGAG
CAAGTTAGGAAATCAACATTGAATCCCAATGCAAAGGAGTTCAACCCACGTTCCTTCTCTCAGCCAAAGCCTTCTACTACCCCAACTTCA
CCTCGGCCTCAAGCACAACCTAGCCCATCTATGGTGGGTCATCAACAGCCAACTCCAGTTTATACTCAGCCTGTTTGTTTTGCACCAAAT
ATGATGTATCCAGTCCCAGTGAGCCCAGGCGTGCAACCTTTATACCCAATACCTATGACGCCCATGCCAGTGAATCAAGCCAAGACATAT
AGAGCAGATACACATTCCAGTTTTCCTGATGGTGAACAAATAGGCCCTGAAGATCTCAGCTTCAATACAGATGAAAATAGTGGAAGGTAA
TTGCCAAATCAAGAGAACTGACTTGCAAGCTACCTTGACCCTGAATTTTGCTGTAGTTGGTGCTCAAATTTGTCATCAGTCAGATAATCA
GATTTGGTCTTATTTCTTCATTATCTCGACCTGAAATAGTAATTTGGAAACTGTTGGAAGGTGGCACAGTTTAGTCTAAGACAGCAGTAG
TACATGGGAAAAACAGTATGGGAAGAGTTCTTTGTAATGTAAGGAAATAACAATGTAGTTCTCTATTAATTTAGCAAATTTGTACATTCA
CAAAAGGCAGTTTGTCTACTACAGCAGAAGGCTGGTTAACTGCCAGAAAATGTACCTCCAGGCCCTGCATGCCGTCAGTAACCCGCCCGG
CATTGGTGCTCTACTGTCTTTGGCTAGAGCTTAGTTGTGTTTAAATAATCATCTTTATATTTGGGGTTTTAATTACAGTTCCATTAGTGC
CTGTAGATTAGTGAACAGAAAATTGCTTTGGAAGAGATTCTGCCCTGTAGACACTATGTGAATAACTGAAGTAACACTAGACTGAATCTC
CTTTTTGGAGTATGTATCTTCTCTCACTTGTTCAAGTACAGGCACACTGTTCAACCGCATGGTATCTTTCTGTTGTGTGACTTCTACAAA
TGTAATTTTAAATGAAATTAAGTTAACATGGATTCATTACGTTCCTGGCCCTGTAGACACGTGTAAGATTATTTAAAATTCTTTCATTTT
TTTCTGCCTCTTACTATACGACTGTAGTGCAACAAATATTTTAAAGCCCCCTTTTCTTCTTTATTTTCATTAGTTGTACATTGATTTCAG
TGTCAACACATTTAAAGATTCATTCATGTTGCACAGTGGCTTACATGAACGTGAAACTGTGATATAAGGTTTTCTTTCATACTCATAATT
AGCCCAAAACAGTTGCCAAACTTTGCCATTGTGCTCCTGCATTTGTGTTTGAGCTGCTATATATTTGTGGAAATTACACTGAAAGTTGAC
TAAGAGACTATTGAAAAAGCATGAATAATTAAATATACATGTGAGAGACATCTCATCTGCTGTATTTTACTTAGTGAATATTGTTCACTC
TTCCGTGTCTGATGTCTTGCTGAATGCTGTGACTCATAGTTTACTTTTGTTCAAAATAGTTTGCACTTTTTGTTAATAAAATCAACTTGA

>8437_8437_7_ATXN2-TRIM37_ATXN2_chr12_111923069_ENST00000535949_TRIM37_chr17_57076820_ENST00000262294_length(amino acids)=737AA_BP=710
MRMVHILTSVVCDLVLDAAHEKSTESSSGPKREEIMESILFKCSDFVVVQFKDMDSSYAKRDAFTDSAISAKVNGEHKEKDLEPWDAGEL
TANEELEALENDVSNGWDPNDMFRYNEENYGVVSTYDSSLSSYTVPLERDNSEEFLKREARANQLAEEIESSAQYKARVALENDDRSEEE
KYTAVQRNSSEREGHSINTRENKYIPPGQRNREVISWGSGRQNSPRMGQPGSGSMPSRSTSHTSDFNPNSGSDQRVVNGGVPWPSPCPSP
SSRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSAHGSPAPVSTMPKRMSSEGPPRMSPKAQRHPRNHRVSAGRGSISSGLEF
VSHNPPSEAATPPVARTSPSGGTWSSVVSGVPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEAVAMPIPAASPTPASPASNRA
VTPSSEAKDSRLQDQRQNSPAGNKENIKPNETSPSFSKAENKGISPVVSEHRKQIDDLKKFKNDFRLQPSSTSESMDQLLNKNREGEKSR
DLIKDKIEPSAKDSFIENSSSNCTSGSSKPNSPSISPSILSNTEHKRGPEVTSQGVQTSSPACKQEKDDKEEKKDAAEQVRKSTLNPNAK
EFNPRSFSQPKPSTTPTSPRPQAQPSPSMVGHQQPTPVYTQPVCFAPNMMYPVPVSPGVQPLYPIPMTPMPVNQAKTYRADTHSSFPDGE

--------------------------------------------------------------
>8437_8437_8_ATXN2-TRIM37_ATXN2_chr12_111923069_ENST00000535949_TRIM37_chr17_57076820_ENST00000393065_length(transcript)=2730nt_BP=2257nt
CCCGAGAAAGCAACCCAGCGCGCCGCCCGCTCCTCACGTGTCCCTCCCGGCCCCGGGGCCACCTCACGTTCTGCTTCCGTCTGACCCCTC
CGACTTCCGATTTCTTTTGATGGAATCTATGCAAATATGAGGATGGTTCATATACTTACATCAGTTGTTTGTGATTTGGTACTTGATGCC
GCACATGAGAAAAGTACAGAATCCAGTTCGGGGCCGAAACGTGAAGAAATAATGGAGAGTATTTTGTTCAAATGTTCAGACTTTGTTGTG
GTACAGTTTAAAGATATGGACTCCAGTTATGCAAAAAGAGATGCTTTTACTGACTCTGCTATCAGTGCTAAAGTGAATGGCGAACACAAA
GAGAAGGACCTGGAGCCCTGGGATGCAGGTGAACTCACAGCCAATGAGGAACTTGAGGCTTTGGAAAATGACGTATCTAATGGATGGGAT
CCCAATGATATGTTTCGATATAATGAAGAAAATTATGGTGTAGTGTCTACGTATGATAGCAGTTTATCTTCGTATACAGTGCCCTTAGAA
AGAGATAACTCAGAAGAATTTTTAAAACGGGAAGCAAGGGCAAACCAGTTAGCAGAAGAAATTGAGTCAAGTGCCCAGTACAAAGCTCGA
GTGGCCCTGGAAAATGATGATAGGAGTGAGGAAGAAAAATACACAGCAGTTCAGAGAAATTCCAGTGAACGTGAGGGGCACAGCATAAAC
ACTAGGGAAAATAAATATATTCCTCCTGGACAAAGAAATAGAGAAGTCATATCCTGGGGAAGTGGGAGACAGAATTCACCGCGTATGGGC
CAGCCTGGATCGGGCTCCATGCCATCAAGATCCACTTCTCACACTTCAGATTTCAACCCGAATTCTGGTTCAGACCAAAGAGTAGTTAAT
GGAGGTGTTCCCTGGCCATCGCCTTGCCCATCTCCTTCCTCTCGCCCACCTTCTCGCTACCAGTCAGGTCCCAACTCTCTTCCACCTCGG
GCAGCCACCCCTACACGGCCGCCCTCCAGGCCCCCCTCGCGGCCATCCAGACCCCCGTCTCACCCCTCTGCTCATGGTTCTCCAGCTCCT
GTCTCTACTATGCCTAAACGCATGTCTTCAGAAGGGCCTCCAAGGATGTCCCCAAAGGCCCAGCGACATCCTCGAAATCACAGAGTTTCT
GCTGGGAGGGGTTCCATATCCAGTGGCCTAGAATTTGTATCCCACAACCCACCCAGTGAAGCAGCTACTCCTCCAGTAGCAAGGACCAGT
CCCTCGGGGGGAACGTGGTCATCAGTGGTCAGTGGGGTTCCAAGATTATCCCCTAAAACTCATAGACCCAGGTCTCCCAGACAGAACAGT
ATTGGAAATACCCCCAGTGGGCCAGTTCTTGCTTCTCCCCAAGCTGGTATTATTCCAACTGAAGCTGTTGCCATGCCTATTCCAGCTGCA
TCTCCTACGCCTGCTAGTCCTGCATCGAACAGAGCTGTTACCCCTTCTAGTGAGGCTAAAGATTCCAGGCTTCAAGATCAGAGGCAGAAC
TCTCCTGCAGGGAATAAAGAAAATATTAAACCCAATGAAACATCACCTAGCTTCTCAAAAGCTGAAAACAAAGGTATATCACCAGTTGTT
TCTGAACATAGAAAACAGATTGATGATTTAAAGAAATTTAAGAATGATTTTAGGTTACAGCCAAGTTCTACTTCTGAATCTATGGATCAA
CTACTAAACAAAAATAGAGAGGGAGAAAAATCAAGAGATTTGATCAAAGACAAAATTGAACCAAGTGCTAAGGATTCTTTCATTGAAAAT
AGCAGCAGCAACTGTACCAGTGGCAGCAGCAAGCCGAATAGCCCCAGCATTTCCCCTTCAATACTTAGTAACACGGAGCACAAGAGGGGA
CCTGAGGTCACTTCCCAAGGGGTTCAGACTTCCAGCCCAGCATGTAAACAAGAGAAAGACGATAAGGAAGAGAAGAAAGACGCAGCTGAG
CAAGTTAGGAAATCAACATTGAATCCCAATGCAAAGGAGTTCAACCCACGTTCCTTCTCTCAGCCAAAGCCTTCTACTACCCCAACTTCA
CCTCGGCCTCAAGCACAACCTAGCCCATCTATGGTGGGTCATCAACAGCCAACTCCAGTTTATACTCAGCCTGTTTGTTTTGCACCAAAT
ATGATGTATCCAGTCCCAGTGAGCCCAGGCGTGCAACCTTTATACCCAATACCTATGACGCCCATGCCAGTGAATCAAGCCAAGACATAT
AGAGCAGATACACATTCCAGTTTTCCTGATGGTGAACAAATAGGCCCTGAAGATCTCAGCTTCAATACAGATGAAAATAGTGGAAGGTAA
TTGCCAAATCAAGAGAACTGACTTGCAAGCTACCTTGACCCTGAATTTTGCTGTAGTTGGTGCTCAAATTTGTCATCAGTCAGATAATCA
GATTTGGTCTTATTTCTTCATTATCTCGACCTGAAATAGTAATTTGGAAACTGTTGGAAGGTGGCACAGTTTAGTCTAAGACAGCAGTAG
TACATGGGAAAAACAGTATGGGAAGAGTTCTTTGTAATGTAAGGAAATAACAATGTAGTTCTCTATTAATTTAGCAAATTTGTACATTCA
CAAAAGGCAGTTTGTCTACTACAGCAGAAGGCTGGTTAACTGCCAGAAAATGTACCTCCAGGCCCTGCATGCCGTCAGTAACCCGCCCGG

>8437_8437_8_ATXN2-TRIM37_ATXN2_chr12_111923069_ENST00000535949_TRIM37_chr17_57076820_ENST00000393065_length(amino acids)=737AA_BP=710
MRMVHILTSVVCDLVLDAAHEKSTESSSGPKREEIMESILFKCSDFVVVQFKDMDSSYAKRDAFTDSAISAKVNGEHKEKDLEPWDAGEL
TANEELEALENDVSNGWDPNDMFRYNEENYGVVSTYDSSLSSYTVPLERDNSEEFLKREARANQLAEEIESSAQYKARVALENDDRSEEE
KYTAVQRNSSEREGHSINTRENKYIPPGQRNREVISWGSGRQNSPRMGQPGSGSMPSRSTSHTSDFNPNSGSDQRVVNGGVPWPSPCPSP
SSRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSAHGSPAPVSTMPKRMSSEGPPRMSPKAQRHPRNHRVSAGRGSISSGLEF
VSHNPPSEAATPPVARTSPSGGTWSSVVSGVPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEAVAMPIPAASPTPASPASNRA
VTPSSEAKDSRLQDQRQNSPAGNKENIKPNETSPSFSKAENKGISPVVSEHRKQIDDLKKFKNDFRLQPSSTSESMDQLLNKNREGEKSR
DLIKDKIEPSAKDSFIENSSSNCTSGSSKPNSPSISPSILSNTEHKRGPEVTSQGVQTSSPACKQEKDDKEEKKDAAEQVRKSTLNPNAK
EFNPRSFSQPKPSTTPTSPRPQAQPSPSMVGHQQPTPVYTQPVCFAPNMMYPVPVSPGVQPLYPIPMTPMPVNQAKTYRADTHSSFPDGE

--------------------------------------------------------------
>8437_8437_9_ATXN2-TRIM37_ATXN2_chr12_111923069_ENST00000535949_TRIM37_chr17_57076820_ENST00000393066_length(transcript)=2607nt_BP=2257nt
CCCGAGAAAGCAACCCAGCGCGCCGCCCGCTCCTCACGTGTCCCTCCCGGCCCCGGGGCCACCTCACGTTCTGCTTCCGTCTGACCCCTC
CGACTTCCGATTTCTTTTGATGGAATCTATGCAAATATGAGGATGGTTCATATACTTACATCAGTTGTTTGTGATTTGGTACTTGATGCC
GCACATGAGAAAAGTACAGAATCCAGTTCGGGGCCGAAACGTGAAGAAATAATGGAGAGTATTTTGTTCAAATGTTCAGACTTTGTTGTG
GTACAGTTTAAAGATATGGACTCCAGTTATGCAAAAAGAGATGCTTTTACTGACTCTGCTATCAGTGCTAAAGTGAATGGCGAACACAAA
GAGAAGGACCTGGAGCCCTGGGATGCAGGTGAACTCACAGCCAATGAGGAACTTGAGGCTTTGGAAAATGACGTATCTAATGGATGGGAT
CCCAATGATATGTTTCGATATAATGAAGAAAATTATGGTGTAGTGTCTACGTATGATAGCAGTTTATCTTCGTATACAGTGCCCTTAGAA
AGAGATAACTCAGAAGAATTTTTAAAACGGGAAGCAAGGGCAAACCAGTTAGCAGAAGAAATTGAGTCAAGTGCCCAGTACAAAGCTCGA
GTGGCCCTGGAAAATGATGATAGGAGTGAGGAAGAAAAATACACAGCAGTTCAGAGAAATTCCAGTGAACGTGAGGGGCACAGCATAAAC
ACTAGGGAAAATAAATATATTCCTCCTGGACAAAGAAATAGAGAAGTCATATCCTGGGGAAGTGGGAGACAGAATTCACCGCGTATGGGC
CAGCCTGGATCGGGCTCCATGCCATCAAGATCCACTTCTCACACTTCAGATTTCAACCCGAATTCTGGTTCAGACCAAAGAGTAGTTAAT
GGAGGTGTTCCCTGGCCATCGCCTTGCCCATCTCCTTCCTCTCGCCCACCTTCTCGCTACCAGTCAGGTCCCAACTCTCTTCCACCTCGG
GCAGCCACCCCTACACGGCCGCCCTCCAGGCCCCCCTCGCGGCCATCCAGACCCCCGTCTCACCCCTCTGCTCATGGTTCTCCAGCTCCT
GTCTCTACTATGCCTAAACGCATGTCTTCAGAAGGGCCTCCAAGGATGTCCCCAAAGGCCCAGCGACATCCTCGAAATCACAGAGTTTCT
GCTGGGAGGGGTTCCATATCCAGTGGCCTAGAATTTGTATCCCACAACCCACCCAGTGAAGCAGCTACTCCTCCAGTAGCAAGGACCAGT
CCCTCGGGGGGAACGTGGTCATCAGTGGTCAGTGGGGTTCCAAGATTATCCCCTAAAACTCATAGACCCAGGTCTCCCAGACAGAACAGT
ATTGGAAATACCCCCAGTGGGCCAGTTCTTGCTTCTCCCCAAGCTGGTATTATTCCAACTGAAGCTGTTGCCATGCCTATTCCAGCTGCA
TCTCCTACGCCTGCTAGTCCTGCATCGAACAGAGCTGTTACCCCTTCTAGTGAGGCTAAAGATTCCAGGCTTCAAGATCAGAGGCAGAAC
TCTCCTGCAGGGAATAAAGAAAATATTAAACCCAATGAAACATCACCTAGCTTCTCAAAAGCTGAAAACAAAGGTATATCACCAGTTGTT
TCTGAACATAGAAAACAGATTGATGATTTAAAGAAATTTAAGAATGATTTTAGGTTACAGCCAAGTTCTACTTCTGAATCTATGGATCAA
CTACTAAACAAAAATAGAGAGGGAGAAAAATCAAGAGATTTGATCAAAGACAAAATTGAACCAAGTGCTAAGGATTCTTTCATTGAAAAT
AGCAGCAGCAACTGTACCAGTGGCAGCAGCAAGCCGAATAGCCCCAGCATTTCCCCTTCAATACTTAGTAACACGGAGCACAAGAGGGGA
CCTGAGGTCACTTCCCAAGGGGTTCAGACTTCCAGCCCAGCATGTAAACAAGAGAAAGACGATAAGGAAGAGAAGAAAGACGCAGCTGAG
CAAGTTAGGAAATCAACATTGAATCCCAATGCAAAGGAGTTCAACCCACGTTCCTTCTCTCAGCCAAAGCCTTCTACTACCCCAACTTCA
CCTCGGCCTCAAGCACAACCTAGCCCATCTATGGTGGGTCATCAACAGCCAACTCCAGTTTATACTCAGCCTGTTTGTTTTGCACCAAAT
ATGATGTATCCAGTCCCAGTGAGCCCAGGCGTGCAACCTTTATACCCAATACCTATGACGCCCATGCCAGTGAATCAAGCCAAGACATAT
AGAGCAGATACACATTCCAGTTTTCCTGATGGTGAACAAATAGGCCCTGAAGATCTCAGCTTCAATACAGATGAAAATAGTGGAAGATAA
TTTGATTTGAAACTGACACTGCACCTGATGGGTTAACAAGATCTAGGCTTCAGAAGGTGACAGATATGAGTGAGGACCATGTGTGGGGCA
AAGCCTCAGAATGATGAAAAGGTTCCGGCACTATAGTTGGGGCCATGTTGACTCCTTTTCAACCATTTGTCACAGACGTGAGAAGAAGAA

>8437_8437_9_ATXN2-TRIM37_ATXN2_chr12_111923069_ENST00000535949_TRIM37_chr17_57076820_ENST00000393066_length(amino acids)=737AA_BP=710
MRMVHILTSVVCDLVLDAAHEKSTESSSGPKREEIMESILFKCSDFVVVQFKDMDSSYAKRDAFTDSAISAKVNGEHKEKDLEPWDAGEL
TANEELEALENDVSNGWDPNDMFRYNEENYGVVSTYDSSLSSYTVPLERDNSEEFLKREARANQLAEEIESSAQYKARVALENDDRSEEE
KYTAVQRNSSEREGHSINTRENKYIPPGQRNREVISWGSGRQNSPRMGQPGSGSMPSRSTSHTSDFNPNSGSDQRVVNGGVPWPSPCPSP
SSRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSAHGSPAPVSTMPKRMSSEGPPRMSPKAQRHPRNHRVSAGRGSISSGLEF
VSHNPPSEAATPPVARTSPSGGTWSSVVSGVPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEAVAMPIPAASPTPASPASNRA
VTPSSEAKDSRLQDQRQNSPAGNKENIKPNETSPSFSKAENKGISPVVSEHRKQIDDLKKFKNDFRLQPSSTSESMDQLLNKNREGEKSR
DLIKDKIEPSAKDSFIENSSSNCTSGSSKPNSPSISPSILSNTEHKRGPEVTSQGVQTSSPACKQEKDDKEEKKDAAEQVRKSTLNPNAK
EFNPRSFSQPKPSTTPTSPRPQAQPSPSMVGHQQPTPVYTQPVCFAPNMMYPVPVSPGVQPLYPIPMTPMPVNQAKTYRADTHSSFPDGE

--------------------------------------------------------------
>8437_8437_10_ATXN2-TRIM37_ATXN2_chr12_111923069_ENST00000608853_TRIM37_chr17_57076820_ENST00000262294_length(transcript)=4092nt_BP=2834nt
TCCCCCGCCCGGCCCCGGCCCCCCTCCCTCCCGGCAGAGCTCGCCTCCCTCCGCCTCAGACTGTTTTGGTAGCAACGGCAACGGCGGCGG
CGCGTTTCGGCCCGGCTCCCGGCGGCTCCTTGGTCTCGGCGGGCCTCCCCGCCCCTTCGTCGTCCTCCTTCTCCCCCTCGCCAGCCCGGG
CGCCCCTCCGGCCGCGCCAACCCGCGCCTCCCCGCTCGGCGCCCGCGCGTCCCCGCCGCGTTCCGGCGTCTCCTTGGCGCGCCCGGCTCC
CGGCTGTCCCCGCCCGGCGTGCGAGCCGGTGTATGGGCCCCTCACCATGTCGCTGAAGCCCCAGCAGCAGCAGCAGCAGCAGCAGCAGCA
GCAGCAGCAGCAACAGCAGCAGCAGCAGCAGCAGCAGCAGCCGCCGCCCGCGGCTGCCAATGTCCGCAAGCCCGGCGGCAGCGGCCTTCT
AGCGTCGCCCGCCGCCGCGCCTTCGCCGTCCTCGTCCTCGGTCTCCTCGTCCTCGGCCACGGCTCCCTCCTCGGTGGTCGCGGCGACCTC
CGGCGGCGGGAGGCCCGGCCTGGGCAGAGGTCGAAACAGTAACAAAGGACTGCCTCAGTCTACGATTTCTTTTGATGGAATCTATGCAAA
TATGAGGATGGTTCATATACTTACATCAGTTGTTGGCTCCAAATGTGAAGTACAAGTGAAAAATGGAGGTATATATGAAGGAGTTTTTAA
AACTTACAGTCCGAAGTGTGATTTGGTACTTGATGCCGCACATGAGAAAAGTACAGAATCCAGTTCGGGGCCGAAACGTGAAGAAATAAT
GGAGAGTATTTTGTTCAAATGTTCAGACTTTGTTGTGGTACAGTTTAAAGATATGGACTCCAGTTATGCAAAAAGAGATGCTTTTACTGA
CTCTGCTATCAGTGCTAAAGTGAATGGCGAACACAAAGAGAAGGACCTGGAGCCCTGGGATGCAGGTGAACTCACAGCCAATGAGGAACT
TGAGGCTTTGGAAAATGACGTATCTAATGGATGGGATCCCAATGATATGTTTCGATATAATGAAGAAAATTATGGTGTAGTGTCTACGTA
TGATAGCAGTTTATCTTCGTATACAGTGCCCTTAGAAAGAGATAACTCAGAAGAATTTTTAAAACGGGAAGCAAGGGCAAACCAGTTAGC
AGAAGAAATTGAGTCAAGTGCCCAGTACAAAGCTCGAGTGGCCCTGGAAAATGATGATAGGAGTGAGGAAGAAAAATACACAGCAGTTCA
GAGAAATTCCAGTGAACGTGAGGGGCACAGCATAAACACTAGGGAAAATAAATATATTCCTCCTGGACAAAGAAATAGAGAAGTCATATC
CTGGGGAAGTGGGAGACAGAATTCACCGCGTATGGGCCAGCCTGGATCGGGCTCCATGCCATCAAGATCCACTTCTCACACTTCAGATTT
CAACCCGAATTCTGGTTCAGACCAAAGAGTAGTTAATGGAGGTGTTCCCTGGCCATCGCCTTGCCCATCTCCTTCCTCTCGCCCACCTTC
TCGCTACCAGTCAGGTCCCAACTCTCTTCCACCTCGGGCAGCCACCCCTACACGGCCGCCCTCCAGGCCCCCCTCGCGGCCATCCAGACC
CCCGTCTCACCCCTCTGCTCATGGTTCTCCAGCTCCTGTCTCTACTATGCCTAAACGCATGTCTTCAGAAGGGCCTCCAAGGATGTCCCC
AAAGGCCCAGCGACATCCTCGAAATCACAGAGTTTCTGCTGGGAGGGGTTCCATATCCAGTGGCCTAGAATTTGTATCCCACAACCCACC
CAGTGAAGCAGCTACTCCTCCAGTAGCAAGGACCAGTCCCTCGGGGGGAACGTGGTCATCAGTGGTCAGTGGGGTTCCAAGATTATCCCC
TAAAACTCATAGACCCAGGTCTCCCAGACAGAACAGTATTGGAAATACCCCCAGTGGGCCAGTTCTTGCTTCTCCCCAAGCTGGTATTAT
TCCAACTGAAGCTGTTGCCATGCCTATTCCAGCTGCATCTCCTACGCCTGCTAGTCCTGCATCGAACAGAGCTGTTACCCCTTCTAGTGA
GGCTAAAGATTCCAGGCTTCAAGATCAGAGGCAGAACTCTCCTGCAGGGAATAAAGAAAATATTAAACCCAATGAAACATCACCTAGCTT
CTCAAAAGCTGAAAACAAAGGTATATCACCAGTTGTTTCTGAACATAGAAAACAGATTGATGATTTAAAGAAATTTAAGAATGATTTTAG
GTTACAGCCAAGTTCTACTTCTGAATCTATGGATCAACTACTAAACAAAAATAGAGAGGGAGAAAAATCAAGAGATTTGATCAAAGACAA
AATTGAACCAAGTGCTAAGGATTCTTTCATTGAAAATAGCAGCAGCAACTGTACCAGTGGCAGCAGCAAGCCGAATAGCCCCAGCATTTC
CCCTTCAATACTTAGTAACACGGAGCACAAGAGGGGACCTGAGGTCACTTCCCAAGGGGTTCAGACTTCCAGCCCAGCATGTAAACAAGA
GAAAGACGATAAGGAAGAGAAGAAAGACGCAGCTGAGCAAGTTAGGAAATCAACATTGAATCCCAATGCAAAGGAGTTCAACCCACGTTC
CTTCTCTCAGCCAAAGCCTTCTACTACCCCAACTTCACCTCGGCCTCAAGCACAACCTAGCCCATCTATGGTGGGTCATCAACAGCCAAC
TCCAGTTTATACTCAGCCTGTTTGTTTTGCACCAAATATGATGTATCCAGTCCCAGTGAGCCCAGGCGTGCAACCTTTATACCCAATACC
TATGACGCCCATGCCAGTGAATCAAGCCAAGACATATAGAGCAGATACACATTCCAGTTTTCCTGATGGTGAACAAATAGGCCCTGAAGA
TCTCAGCTTCAATACAGATGAAAATAGTGGAAGGTAATTGCCAAATCAAGAGAACTGACTTGCAAGCTACCTTGACCCTGAATTTTGCTG
TAGTTGGTGCTCAAATTTGTCATCAGTCAGATAATCAGATTTGGTCTTATTTCTTCATTATCTCGACCTGAAATAGTAATTTGGAAACTG
TTGGAAGGTGGCACAGTTTAGTCTAAGACAGCAGTAGTACATGGGAAAAACAGTATGGGAAGAGTTCTTTGTAATGTAAGGAAATAACAA
TGTAGTTCTCTATTAATTTAGCAAATTTGTACATTCACAAAAGGCAGTTTGTCTACTACAGCAGAAGGCTGGTTAACTGCCAGAAAATGT
ACCTCCAGGCCCTGCATGCCGTCAGTAACCCGCCCGGCATTGGTGCTCTACTGTCTTTGGCTAGAGCTTAGTTGTGTTTAAATAATCATC
TTTATATTTGGGGTTTTAATTACAGTTCCATTAGTGCCTGTAGATTAGTGAACAGAAAATTGCTTTGGAAGAGATTCTGCCCTGTAGACA
CTATGTGAATAACTGAAGTAACACTAGACTGAATCTCCTTTTTGGAGTATGTATCTTCTCTCACTTGTTCAAGTACAGGCACACTGTTCA
ACCGCATGGTATCTTTCTGTTGTGTGACTTCTACAAATGTAATTTTAAATGAAATTAAGTTAACATGGATTCATTACGTTCCTGGCCCTG
TAGACACGTGTAAGATTATTTAAAATTCTTTCATTTTTTTCTGCCTCTTACTATACGACTGTAGTGCAACAAATATTTTAAAGCCCCCTT
TTCTTCTTTATTTTCATTAGTTGTACATTGATTTCAGTGTCAACACATTTAAAGATTCATTCATGTTGCACAGTGGCTTACATGAACGTG
AAACTGTGATATAAGGTTTTCTTTCATACTCATAATTAGCCCAAAACAGTTGCCAAACTTTGCCATTGTGCTCCTGCATTTGTGTTTGAG
CTGCTATATATTTGTGGAAATTACACTGAAAGTTGACTAAGAGACTATTGAAAAAGCATGAATAATTAAATATACATGTGAGAGACATCT
CATCTGCTGTATTTTACTTAGTGAATATTGTTCACTCTTCCGTGTCTGATGTCTTGCTGAATGCTGTGACTCATAGTTTACTTTTGTTCA

>8437_8437_10_ATXN2-TRIM37_ATXN2_chr12_111923069_ENST00000608853_TRIM37_chr17_57076820_ENST00000262294_length(amino acids)=887AA_BP=860
MARPAPGCPRPACEPVYGPLTMSLKPQQQQQQQQQQQQQQQQQQQQQQQPPPAAANVRKPGGSGLLASPAAAPSPSSSSVSSSSATAPSS
VVAATSGGGRPGLGRGRNSNKGLPQSTISFDGIYANMRMVHILTSVVGSKCEVQVKNGGIYEGVFKTYSPKCDLVLDAAHEKSTESSSGP
KREEIMESILFKCSDFVVVQFKDMDSSYAKRDAFTDSAISAKVNGEHKEKDLEPWDAGELTANEELEALENDVSNGWDPNDMFRYNEENY
GVVSTYDSSLSSYTVPLERDNSEEFLKREARANQLAEEIESSAQYKARVALENDDRSEEEKYTAVQRNSSEREGHSINTRENKYIPPGQR
NREVISWGSGRQNSPRMGQPGSGSMPSRSTSHTSDFNPNSGSDQRVVNGGVPWPSPCPSPSSRPPSRYQSGPNSLPPRAATPTRPPSRPP
SRPSRPPSHPSAHGSPAPVSTMPKRMSSEGPPRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAATPPVARTSPSGGTWSSVVSG
VPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEAVAMPIPAASPTPASPASNRAVTPSSEAKDSRLQDQRQNSPAGNKENIKPN
ETSPSFSKAENKGISPVVSEHRKQIDDLKKFKNDFRLQPSSTSESMDQLLNKNREGEKSRDLIKDKIEPSAKDSFIENSSSNCTSGSSKP
NSPSISPSILSNTEHKRGPEVTSQGVQTSSPACKQEKDDKEEKKDAAEQVRKSTLNPNAKEFNPRSFSQPKPSTTPTSPRPQAQPSPSMV

--------------------------------------------------------------
>8437_8437_11_ATXN2-TRIM37_ATXN2_chr12_111923069_ENST00000608853_TRIM37_chr17_57076820_ENST00000393065_length(transcript)=3307nt_BP=2834nt
TCCCCCGCCCGGCCCCGGCCCCCCTCCCTCCCGGCAGAGCTCGCCTCCCTCCGCCTCAGACTGTTTTGGTAGCAACGGCAACGGCGGCGG
CGCGTTTCGGCCCGGCTCCCGGCGGCTCCTTGGTCTCGGCGGGCCTCCCCGCCCCTTCGTCGTCCTCCTTCTCCCCCTCGCCAGCCCGGG
CGCCCCTCCGGCCGCGCCAACCCGCGCCTCCCCGCTCGGCGCCCGCGCGTCCCCGCCGCGTTCCGGCGTCTCCTTGGCGCGCCCGGCTCC
CGGCTGTCCCCGCCCGGCGTGCGAGCCGGTGTATGGGCCCCTCACCATGTCGCTGAAGCCCCAGCAGCAGCAGCAGCAGCAGCAGCAGCA
GCAGCAGCAGCAACAGCAGCAGCAGCAGCAGCAGCAGCAGCCGCCGCCCGCGGCTGCCAATGTCCGCAAGCCCGGCGGCAGCGGCCTTCT
AGCGTCGCCCGCCGCCGCGCCTTCGCCGTCCTCGTCCTCGGTCTCCTCGTCCTCGGCCACGGCTCCCTCCTCGGTGGTCGCGGCGACCTC
CGGCGGCGGGAGGCCCGGCCTGGGCAGAGGTCGAAACAGTAACAAAGGACTGCCTCAGTCTACGATTTCTTTTGATGGAATCTATGCAAA
TATGAGGATGGTTCATATACTTACATCAGTTGTTGGCTCCAAATGTGAAGTACAAGTGAAAAATGGAGGTATATATGAAGGAGTTTTTAA
AACTTACAGTCCGAAGTGTGATTTGGTACTTGATGCCGCACATGAGAAAAGTACAGAATCCAGTTCGGGGCCGAAACGTGAAGAAATAAT
GGAGAGTATTTTGTTCAAATGTTCAGACTTTGTTGTGGTACAGTTTAAAGATATGGACTCCAGTTATGCAAAAAGAGATGCTTTTACTGA
CTCTGCTATCAGTGCTAAAGTGAATGGCGAACACAAAGAGAAGGACCTGGAGCCCTGGGATGCAGGTGAACTCACAGCCAATGAGGAACT
TGAGGCTTTGGAAAATGACGTATCTAATGGATGGGATCCCAATGATATGTTTCGATATAATGAAGAAAATTATGGTGTAGTGTCTACGTA
TGATAGCAGTTTATCTTCGTATACAGTGCCCTTAGAAAGAGATAACTCAGAAGAATTTTTAAAACGGGAAGCAAGGGCAAACCAGTTAGC
AGAAGAAATTGAGTCAAGTGCCCAGTACAAAGCTCGAGTGGCCCTGGAAAATGATGATAGGAGTGAGGAAGAAAAATACACAGCAGTTCA
GAGAAATTCCAGTGAACGTGAGGGGCACAGCATAAACACTAGGGAAAATAAATATATTCCTCCTGGACAAAGAAATAGAGAAGTCATATC
CTGGGGAAGTGGGAGACAGAATTCACCGCGTATGGGCCAGCCTGGATCGGGCTCCATGCCATCAAGATCCACTTCTCACACTTCAGATTT
CAACCCGAATTCTGGTTCAGACCAAAGAGTAGTTAATGGAGGTGTTCCCTGGCCATCGCCTTGCCCATCTCCTTCCTCTCGCCCACCTTC
TCGCTACCAGTCAGGTCCCAACTCTCTTCCACCTCGGGCAGCCACCCCTACACGGCCGCCCTCCAGGCCCCCCTCGCGGCCATCCAGACC
CCCGTCTCACCCCTCTGCTCATGGTTCTCCAGCTCCTGTCTCTACTATGCCTAAACGCATGTCTTCAGAAGGGCCTCCAAGGATGTCCCC
AAAGGCCCAGCGACATCCTCGAAATCACAGAGTTTCTGCTGGGAGGGGTTCCATATCCAGTGGCCTAGAATTTGTATCCCACAACCCACC
CAGTGAAGCAGCTACTCCTCCAGTAGCAAGGACCAGTCCCTCGGGGGGAACGTGGTCATCAGTGGTCAGTGGGGTTCCAAGATTATCCCC
TAAAACTCATAGACCCAGGTCTCCCAGACAGAACAGTATTGGAAATACCCCCAGTGGGCCAGTTCTTGCTTCTCCCCAAGCTGGTATTAT
TCCAACTGAAGCTGTTGCCATGCCTATTCCAGCTGCATCTCCTACGCCTGCTAGTCCTGCATCGAACAGAGCTGTTACCCCTTCTAGTGA
GGCTAAAGATTCCAGGCTTCAAGATCAGAGGCAGAACTCTCCTGCAGGGAATAAAGAAAATATTAAACCCAATGAAACATCACCTAGCTT
CTCAAAAGCTGAAAACAAAGGTATATCACCAGTTGTTTCTGAACATAGAAAACAGATTGATGATTTAAAGAAATTTAAGAATGATTTTAG
GTTACAGCCAAGTTCTACTTCTGAATCTATGGATCAACTACTAAACAAAAATAGAGAGGGAGAAAAATCAAGAGATTTGATCAAAGACAA
AATTGAACCAAGTGCTAAGGATTCTTTCATTGAAAATAGCAGCAGCAACTGTACCAGTGGCAGCAGCAAGCCGAATAGCCCCAGCATTTC
CCCTTCAATACTTAGTAACACGGAGCACAAGAGGGGACCTGAGGTCACTTCCCAAGGGGTTCAGACTTCCAGCCCAGCATGTAAACAAGA
GAAAGACGATAAGGAAGAGAAGAAAGACGCAGCTGAGCAAGTTAGGAAATCAACATTGAATCCCAATGCAAAGGAGTTCAACCCACGTTC
CTTCTCTCAGCCAAAGCCTTCTACTACCCCAACTTCACCTCGGCCTCAAGCACAACCTAGCCCATCTATGGTGGGTCATCAACAGCCAAC
TCCAGTTTATACTCAGCCTGTTTGTTTTGCACCAAATATGATGTATCCAGTCCCAGTGAGCCCAGGCGTGCAACCTTTATACCCAATACC
TATGACGCCCATGCCAGTGAATCAAGCCAAGACATATAGAGCAGATACACATTCCAGTTTTCCTGATGGTGAACAAATAGGCCCTGAAGA
TCTCAGCTTCAATACAGATGAAAATAGTGGAAGGTAATTGCCAAATCAAGAGAACTGACTTGCAAGCTACCTTGACCCTGAATTTTGCTG
TAGTTGGTGCTCAAATTTGTCATCAGTCAGATAATCAGATTTGGTCTTATTTCTTCATTATCTCGACCTGAAATAGTAATTTGGAAACTG
TTGGAAGGTGGCACAGTTTAGTCTAAGACAGCAGTAGTACATGGGAAAAACAGTATGGGAAGAGTTCTTTGTAATGTAAGGAAATAACAA
TGTAGTTCTCTATTAATTTAGCAAATTTGTACATTCACAAAAGGCAGTTTGTCTACTACAGCAGAAGGCTGGTTAACTGCCAGAAAATGT

>8437_8437_11_ATXN2-TRIM37_ATXN2_chr12_111923069_ENST00000608853_TRIM37_chr17_57076820_ENST00000393065_length(amino acids)=887AA_BP=860
MARPAPGCPRPACEPVYGPLTMSLKPQQQQQQQQQQQQQQQQQQQQQQQPPPAAANVRKPGGSGLLASPAAAPSPSSSSVSSSSATAPSS
VVAATSGGGRPGLGRGRNSNKGLPQSTISFDGIYANMRMVHILTSVVGSKCEVQVKNGGIYEGVFKTYSPKCDLVLDAAHEKSTESSSGP
KREEIMESILFKCSDFVVVQFKDMDSSYAKRDAFTDSAISAKVNGEHKEKDLEPWDAGELTANEELEALENDVSNGWDPNDMFRYNEENY
GVVSTYDSSLSSYTVPLERDNSEEFLKREARANQLAEEIESSAQYKARVALENDDRSEEEKYTAVQRNSSEREGHSINTRENKYIPPGQR
NREVISWGSGRQNSPRMGQPGSGSMPSRSTSHTSDFNPNSGSDQRVVNGGVPWPSPCPSPSSRPPSRYQSGPNSLPPRAATPTRPPSRPP
SRPSRPPSHPSAHGSPAPVSTMPKRMSSEGPPRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAATPPVARTSPSGGTWSSVVSG
VPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEAVAMPIPAASPTPASPASNRAVTPSSEAKDSRLQDQRQNSPAGNKENIKPN
ETSPSFSKAENKGISPVVSEHRKQIDDLKKFKNDFRLQPSSTSESMDQLLNKNREGEKSRDLIKDKIEPSAKDSFIENSSSNCTSGSSKP
NSPSISPSILSNTEHKRGPEVTSQGVQTSSPACKQEKDDKEEKKDAAEQVRKSTLNPNAKEFNPRSFSQPKPSTTPTSPRPQAQPSPSMV

--------------------------------------------------------------
>8437_8437_12_ATXN2-TRIM37_ATXN2_chr12_111923069_ENST00000608853_TRIM37_chr17_57076820_ENST00000393066_length(transcript)=3184nt_BP=2834nt
TCCCCCGCCCGGCCCCGGCCCCCCTCCCTCCCGGCAGAGCTCGCCTCCCTCCGCCTCAGACTGTTTTGGTAGCAACGGCAACGGCGGCGG
CGCGTTTCGGCCCGGCTCCCGGCGGCTCCTTGGTCTCGGCGGGCCTCCCCGCCCCTTCGTCGTCCTCCTTCTCCCCCTCGCCAGCCCGGG
CGCCCCTCCGGCCGCGCCAACCCGCGCCTCCCCGCTCGGCGCCCGCGCGTCCCCGCCGCGTTCCGGCGTCTCCTTGGCGCGCCCGGCTCC
CGGCTGTCCCCGCCCGGCGTGCGAGCCGGTGTATGGGCCCCTCACCATGTCGCTGAAGCCCCAGCAGCAGCAGCAGCAGCAGCAGCAGCA
GCAGCAGCAGCAACAGCAGCAGCAGCAGCAGCAGCAGCAGCCGCCGCCCGCGGCTGCCAATGTCCGCAAGCCCGGCGGCAGCGGCCTTCT
AGCGTCGCCCGCCGCCGCGCCTTCGCCGTCCTCGTCCTCGGTCTCCTCGTCCTCGGCCACGGCTCCCTCCTCGGTGGTCGCGGCGACCTC
CGGCGGCGGGAGGCCCGGCCTGGGCAGAGGTCGAAACAGTAACAAAGGACTGCCTCAGTCTACGATTTCTTTTGATGGAATCTATGCAAA
TATGAGGATGGTTCATATACTTACATCAGTTGTTGGCTCCAAATGTGAAGTACAAGTGAAAAATGGAGGTATATATGAAGGAGTTTTTAA
AACTTACAGTCCGAAGTGTGATTTGGTACTTGATGCCGCACATGAGAAAAGTACAGAATCCAGTTCGGGGCCGAAACGTGAAGAAATAAT
GGAGAGTATTTTGTTCAAATGTTCAGACTTTGTTGTGGTACAGTTTAAAGATATGGACTCCAGTTATGCAAAAAGAGATGCTTTTACTGA
CTCTGCTATCAGTGCTAAAGTGAATGGCGAACACAAAGAGAAGGACCTGGAGCCCTGGGATGCAGGTGAACTCACAGCCAATGAGGAACT
TGAGGCTTTGGAAAATGACGTATCTAATGGATGGGATCCCAATGATATGTTTCGATATAATGAAGAAAATTATGGTGTAGTGTCTACGTA
TGATAGCAGTTTATCTTCGTATACAGTGCCCTTAGAAAGAGATAACTCAGAAGAATTTTTAAAACGGGAAGCAAGGGCAAACCAGTTAGC
AGAAGAAATTGAGTCAAGTGCCCAGTACAAAGCTCGAGTGGCCCTGGAAAATGATGATAGGAGTGAGGAAGAAAAATACACAGCAGTTCA
GAGAAATTCCAGTGAACGTGAGGGGCACAGCATAAACACTAGGGAAAATAAATATATTCCTCCTGGACAAAGAAATAGAGAAGTCATATC
CTGGGGAAGTGGGAGACAGAATTCACCGCGTATGGGCCAGCCTGGATCGGGCTCCATGCCATCAAGATCCACTTCTCACACTTCAGATTT
CAACCCGAATTCTGGTTCAGACCAAAGAGTAGTTAATGGAGGTGTTCCCTGGCCATCGCCTTGCCCATCTCCTTCCTCTCGCCCACCTTC
TCGCTACCAGTCAGGTCCCAACTCTCTTCCACCTCGGGCAGCCACCCCTACACGGCCGCCCTCCAGGCCCCCCTCGCGGCCATCCAGACC
CCCGTCTCACCCCTCTGCTCATGGTTCTCCAGCTCCTGTCTCTACTATGCCTAAACGCATGTCTTCAGAAGGGCCTCCAAGGATGTCCCC
AAAGGCCCAGCGACATCCTCGAAATCACAGAGTTTCTGCTGGGAGGGGTTCCATATCCAGTGGCCTAGAATTTGTATCCCACAACCCACC
CAGTGAAGCAGCTACTCCTCCAGTAGCAAGGACCAGTCCCTCGGGGGGAACGTGGTCATCAGTGGTCAGTGGGGTTCCAAGATTATCCCC
TAAAACTCATAGACCCAGGTCTCCCAGACAGAACAGTATTGGAAATACCCCCAGTGGGCCAGTTCTTGCTTCTCCCCAAGCTGGTATTAT
TCCAACTGAAGCTGTTGCCATGCCTATTCCAGCTGCATCTCCTACGCCTGCTAGTCCTGCATCGAACAGAGCTGTTACCCCTTCTAGTGA
GGCTAAAGATTCCAGGCTTCAAGATCAGAGGCAGAACTCTCCTGCAGGGAATAAAGAAAATATTAAACCCAATGAAACATCACCTAGCTT
CTCAAAAGCTGAAAACAAAGGTATATCACCAGTTGTTTCTGAACATAGAAAACAGATTGATGATTTAAAGAAATTTAAGAATGATTTTAG
GTTACAGCCAAGTTCTACTTCTGAATCTATGGATCAACTACTAAACAAAAATAGAGAGGGAGAAAAATCAAGAGATTTGATCAAAGACAA
AATTGAACCAAGTGCTAAGGATTCTTTCATTGAAAATAGCAGCAGCAACTGTACCAGTGGCAGCAGCAAGCCGAATAGCCCCAGCATTTC
CCCTTCAATACTTAGTAACACGGAGCACAAGAGGGGACCTGAGGTCACTTCCCAAGGGGTTCAGACTTCCAGCCCAGCATGTAAACAAGA
GAAAGACGATAAGGAAGAGAAGAAAGACGCAGCTGAGCAAGTTAGGAAATCAACATTGAATCCCAATGCAAAGGAGTTCAACCCACGTTC
CTTCTCTCAGCCAAAGCCTTCTACTACCCCAACTTCACCTCGGCCTCAAGCACAACCTAGCCCATCTATGGTGGGTCATCAACAGCCAAC
TCCAGTTTATACTCAGCCTGTTTGTTTTGCACCAAATATGATGTATCCAGTCCCAGTGAGCCCAGGCGTGCAACCTTTATACCCAATACC
TATGACGCCCATGCCAGTGAATCAAGCCAAGACATATAGAGCAGATACACATTCCAGTTTTCCTGATGGTGAACAAATAGGCCCTGAAGA
TCTCAGCTTCAATACAGATGAAAATAGTGGAAGATAATTTGATTTGAAACTGACACTGCACCTGATGGGTTAACAAGATCTAGGCTTCAG
AAGGTGACAGATATGAGTGAGGACCATGTGTGGGGCAAAGCCTCAGAATGATGAAAAGGTTCCGGCACTATAGTTGGGGCCATGTTGACT
CCTTTTCAACCATTTGTCACAGACGTGAGAAGAAGAAATGACTTCAAAATCAAGAGAAAACAAATACTGAAAGTCTCTACTTACATCCAA

>8437_8437_12_ATXN2-TRIM37_ATXN2_chr12_111923069_ENST00000608853_TRIM37_chr17_57076820_ENST00000393066_length(amino acids)=887AA_BP=860
MARPAPGCPRPACEPVYGPLTMSLKPQQQQQQQQQQQQQQQQQQQQQQQPPPAAANVRKPGGSGLLASPAAAPSPSSSSVSSSSATAPSS
VVAATSGGGRPGLGRGRNSNKGLPQSTISFDGIYANMRMVHILTSVVGSKCEVQVKNGGIYEGVFKTYSPKCDLVLDAAHEKSTESSSGP
KREEIMESILFKCSDFVVVQFKDMDSSYAKRDAFTDSAISAKVNGEHKEKDLEPWDAGELTANEELEALENDVSNGWDPNDMFRYNEENY
GVVSTYDSSLSSYTVPLERDNSEEFLKREARANQLAEEIESSAQYKARVALENDDRSEEEKYTAVQRNSSEREGHSINTRENKYIPPGQR
NREVISWGSGRQNSPRMGQPGSGSMPSRSTSHTSDFNPNSGSDQRVVNGGVPWPSPCPSPSSRPPSRYQSGPNSLPPRAATPTRPPSRPP
SRPSRPPSHPSAHGSPAPVSTMPKRMSSEGPPRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAATPPVARTSPSGGTWSSVVSG
VPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEAVAMPIPAASPTPASPASNRAVTPSSEAKDSRLQDQRQNSPAGNKENIKPN
ETSPSFSKAENKGISPVVSEHRKQIDDLKKFKNDFRLQPSSTSESMDQLLNKNREGEKSRDLIKDKIEPSAKDSFIENSSSNCTSGSSKP
NSPSISPSILSNTEHKRGPEVTSQGVQTSSPACKQEKDDKEEKKDAAEQVRKSTLNPNAKEFNPRSFSQPKPSTTPTSPRPQAQPSPSMV

--------------------------------------------------------------
>8437_8437_13_ATXN2-TRIM37_ATXN2_chr12_111923075_ENST00000377617_TRIM37_chr17_57079075_ENST00000262294_length(transcript)=4535nt_BP=3160nt
ACCCCCGAGAAAGCAACCCAGCGCGCCGCCCGCTCCTCACGTGTCCCTCCCGGCCCCGGGGCCACCTCACGTTCTGCTTCCGTCTGACCC
CTCCGACTTCCGGTAAAGAGTCCCTATCCGCACCTCCGCTCCCACCCGGCGCCTCGGCGCGCCCGCCCTCCGATGCGCTCAGCGGCCGCA
GCTCCTCGGAGTCCCGCGGTGGCCACCGAGTCTCGCCGCTTCGCCGCAGCCAGGTGGCCCGGGTGGCGCTCGCTCCAGCGGCCGGCGCGG
CGGAGCGGGCGGGGCGGCGGTGGCGCGGCCCCGGGACCGTATCCCTCCGCCGCCCCTCCCCCGCCCGGCCCCGGCCCCCCTCCCTCCCGG
CAGAGCTCGCCTCCCTCCGCCTCAGACTGTTTTGGTAGCAACGGCAACGGCGGCGGCGCGTTTCGGCCCGGCTCCCGGCGGCTCCTTGGT
CTCGGCGGGCCTCCCCGCCCCTTCGTCGTCCTCCTTCTCCCCCTCGCCAGCCCGGGCGCCCCTCCGGCCGCGCCAACCCGCGCCTCCCCG
CTCGGCGCCCGCGCGTCCCCGCCGCGTTCCGGCGTCTCCTTGGCGCGCCCGGCTCCCGGCTGTCCCCGCCCGGCGTGCGAGCCGGTGTAT
GGGCCCCTCACCATGTCGCTGAAGCCCCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAACAGCAGCAGCAGCAGCAGCAG
CAGCAGCCGCCGCCCGCGGCTGCCAATGTCCGCAAGCCCGGCGGCAGCGGCCTTCTAGCGTCGCCCGCCGCCGCGCCTTCGCCGTCCTCG
TCCTCGGTCTCCTCGTCCTCGGCCACGGCTCCCTCCTCGGTGGTCGCGGCGACCTCCGGCGGCGGGAGGCCCGGCCTGGGCAGAGGTCGA
AACAGTAACAAAGGACTGCCTCAGTCTACGATTTCTTTTGATGGAATCTATGCAAATATGAGGATGGTTCATATACTTACATCAGTTGTT
GGCTCCAAATGTGAAGTACAAGTGAAAAATGGAGGTATATATGAAGGAGTTTTTAAAACTTACAGTCCGAAGTGTGATTTGGTACTTGAT
GCCGCACATGAGAAAAGTACAGAATCCAGTTCGGGGCCGAAACGTGAAGAAATAATGGAGAGTATTTTGTTCAAATGTTCAGACTTTGTT
GTGGTACAGTTTAAAGATATGGACTCCAGTTATGCAAAAAGAGATGCTTTTACTGACTCTGCTATCAGTGCTAAAGTGAATGGCGAACAC
AAAGAGAAGGACCTGGAGCCCTGGGATGCAGGTGAACTCACAGCCAATGAGGAACTTGAGGCTTTGGAAAATGACGTATCTAATGGATGG
GATCCCAATGATATGTTTCGATATAATGAAGAAAATTATGGTGTAGTGTCTACGTATGATAGCAGTTTATCTTCGTATACAGTGCCCTTA
GAAAGAGATAACTCAGAAGAATTTTTAAAACGGGAAGCAAGGGCAAACCAGTTAGCAGAAGAAATTGAGTCAAGTGCCCAGTACAAAGCT
CGAGTGGCCCTGGAAAATGATGATAGGAGTGAGGAAGAAAAATACACAGCAGTTCAGAGAAATTCCAGTGAACGTGAGGGGCACAGCATA
AACACTAGGGAAAATAAATATATTCCTCCTGGACAAAGAAATAGAGAAGTCATATCCTGGGGAAGTGGGAGACAGAATTCACCGCGTATG
GGCCAGCCTGGATCGGGCTCCATGCCATCAAGATCCACTTCTCACACTTCAGATTTCAACCCGAATTCTGGTTCAGACCAAAGAGTAGTT
AATGGAGGTGTTCCCTGGCCATCGCCTTGCCCATCTCCTTCCTCTCGCCCACCTTCTCGCTACCAGTCAGGTCCCAACTCTCTTCCACCT
CGGGCAGCCACCCCTACACGGCCGCCCTCCAGGCCCCCCTCGCGGCCATCCAGACCCCCGTCTCACCCCTCTGCTCATGGTTCTCCAGCT
CCTGTCTCTACTATGCCTAAACGCATGTCTTCAGAAGGGCCTCCAAGGATGTCCCCAAAGGCCCAGCGACATCCTCGAAATCACAGAGTT
TCTGCTGGGAGGGGTTCCATATCCAGTGGCCTAGAATTTGTATCCCACAACCCACCCAGTGAAGCAGCTACTCCTCCAGTAGCAAGGACC
AGTCCCTCGGGGGGAACGTGGTCATCAGTGGTCAGTGGGGTTCCAAGATTATCCCCTAAAACTCATAGACCCAGGTCTCCCAGACAGAAC
AGTATTGGAAATACCCCCAGTGGGCCAGTTCTTGCTTCTCCCCAAGCTGGTATTATTCCAACTGAAGCTGTTGCCATGCCTATTCCAGCT
GCATCTCCTACGCCTGCTAGTCCTGCATCGAACAGAGCTGTTACCCCTTCTAGTGAGGCTAAAGATTCCAGGCTTCAAGATCAGAGGCAG
AACTCTCCTGCAGGGAATAAAGAAAATATTAAACCCAATGAAACATCACCTAGCTTCTCAAAAGCTGAAAACAAAGGTATATCACCAGTT
GTTTCTGAACATAGAAAACAGATTGATGATTTAAAGAAATTTAAGAATGATTTTAGGTTACAGCCAAGTTCTACTTCTGAATCTATGGAT
CAACTACTAAACAAAAATAGAGAGGGAGAAAAATCAAGAGATTTGATCAAAGACAAAATTGAACCAAGTGCTAAGGATTCTTTCATTGAA
AATAGCAGCAGCAACTGTACCAGTGGCAGCAGCAAGCCGAATAGCCCCAGCATTTCCCCTTCAATACTTAGTAACACGGAGCACAAGAGG
GGACCTGAGGTCACTTCCCAAGGGGTTCAGACTTCCAGCCCAGCATGTAAACAAGAGAAAGACGATAAGGAAGAGAAGAAAGACGCAGCT
GAGCAAGTTAGGAAATCAACATTGAATCCCAATGCAAAGGAGTTCAACCCACGTTCCTTCTCTCAGCCAAAGCCTTCTACTACCCCAACT
TCACCTCGGCCTCAAGCACAACCTAGCCCATCTATGGTGGGTCATCAACAGCCAACTCCAGTTTATACTCAGCCTGTTTGTTTTGCACCA
AATATGATGTATCCAGTCCCAGTGAGCCCAGGCGTGCAACCTTTATACCCAATACCTATGACGCCCATGCCAGTGAATCAAGCCAAGACA
TATAGAGCAGGAATGAGTAGCGACAGTGACATTGAATGTGACACTGAGAATGAGGAGCAGGAAGAGCATACCAGTGTGGGCGGGTTTCAC
GACTCCTTCATGGTCATGACACAGCCCCCGGATGAAGATACACATTCCAGTTTTCCTGATGGTGAACAAATAGGCCCTGAAGATCTCAGC
TTCAATACAGATGAAAATAGTGGAAGGTAATTGCCAAATCAAGAGAACTGACTTGCAAGCTACCTTGACCCTGAATTTTGCTGTAGTTGG
TGCTCAAATTTGTCATCAGTCAGATAATCAGATTTGGTCTTATTTCTTCATTATCTCGACCTGAAATAGTAATTTGGAAACTGTTGGAAG
GTGGCACAGTTTAGTCTAAGACAGCAGTAGTACATGGGAAAAACAGTATGGGAAGAGTTCTTTGTAATGTAAGGAAATAACAATGTAGTT
CTCTATTAATTTAGCAAATTTGTACATTCACAAAAGGCAGTTTGTCTACTACAGCAGAAGGCTGGTTAACTGCCAGAAAATGTACCTCCA
GGCCCTGCATGCCGTCAGTAACCCGCCCGGCATTGGTGCTCTACTGTCTTTGGCTAGAGCTTAGTTGTGTTTAAATAATCATCTTTATAT
TTGGGGTTTTAATTACAGTTCCATTAGTGCCTGTAGATTAGTGAACAGAAAATTGCTTTGGAAGAGATTCTGCCCTGTAGACACTATGTG
AATAACTGAAGTAACACTAGACTGAATCTCCTTTTTGGAGTATGTATCTTCTCTCACTTGTTCAAGTACAGGCACACTGTTCAACCGCAT
GGTATCTTTCTGTTGTGTGACTTCTACAAATGTAATTTTAAATGAAATTAAGTTAACATGGATTCATTACGTTCCTGGCCCTGTAGACAC
GTGTAAGATTATTTAAAATTCTTTCATTTTTTTCTGCCTCTTACTATACGACTGTAGTGCAACAAATATTTTAAAGCCCCCTTTTCTTCT
TTATTTTCATTAGTTGTACATTGATTTCAGTGTCAACACATTTAAAGATTCATTCATGTTGCACAGTGGCTTACATGAACGTGAAACTGT
GATATAAGGTTTTCTTTCATACTCATAATTAGCCCAAAACAGTTGCCAAACTTTGCCATTGTGCTCCTGCATTTGTGTTTGAGCTGCTAT
ATATTTGTGGAAATTACACTGAAAGTTGACTAAGAGACTATTGAAAAAGCATGAATAATTAAATATACATGTGAGAGACATCTCATCTGC
TGTATTTTACTTAGTGAATATTGTTCACTCTTCCGTGTCTGATGTCTTGCTGAATGCTGTGACTCATAGTTTACTTTTGTTCAAAATAGT

>8437_8437_13_ATXN2-TRIM37_ATXN2_chr12_111923075_ENST00000377617_TRIM37_chr17_57079075_ENST00000262294_length(amino acids)=1065AA_BP=999
MRSAAAAPRSPAVATESRRFAAARWPGWRSLQRPARRSGRGGGGAAPGPYPSAAPPPPGPGPPPSRQSSPPSASDCFGSNGNGGGAFRPG
SRRLLGLGGPPRPFVVLLLPLASPGAPPAAPTRASPLGARASPPRSGVSLARPAPGCPRPACEPVYGPLTMSLKPQQQQQQQQQQQQQQQ
QQQQQQQQPPPAAANVRKPGGSGLLASPAAAPSPSSSSVSSSSATAPSSVVAATSGGGRPGLGRGRNSNKGLPQSTISFDGIYANMRMVH
ILTSVVGSKCEVQVKNGGIYEGVFKTYSPKCDLVLDAAHEKSTESSSGPKREEIMESILFKCSDFVVVQFKDMDSSYAKRDAFTDSAISA
KVNGEHKEKDLEPWDAGELTANEELEALENDVSNGWDPNDMFRYNEENYGVVSTYDSSLSSYTVPLERDNSEEFLKREARANQLAEEIES
SAQYKARVALENDDRSEEEKYTAVQRNSSEREGHSINTRENKYIPPGQRNREVISWGSGRQNSPRMGQPGSGSMPSRSTSHTSDFNPNSG
SDQRVVNGGVPWPSPCPSPSSRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSAHGSPAPVSTMPKRMSSEGPPRMSPKAQRH
PRNHRVSAGRGSISSGLEFVSHNPPSEAATPPVARTSPSGGTWSSVVSGVPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEAV
AMPIPAASPTPASPASNRAVTPSSEAKDSRLQDQRQNSPAGNKENIKPNETSPSFSKAENKGISPVVSEHRKQIDDLKKFKNDFRLQPSS
TSESMDQLLNKNREGEKSRDLIKDKIEPSAKDSFIENSSSNCTSGSSKPNSPSISPSILSNTEHKRGPEVTSQGVQTSSPACKQEKDDKE
EKKDAAEQVRKSTLNPNAKEFNPRSFSQPKPSTTPTSPRPQAQPSPSMVGHQQPTPVYTQPVCFAPNMMYPVPVSPGVQPLYPIPMTPMP

--------------------------------------------------------------
>8437_8437_14_ATXN2-TRIM37_ATXN2_chr12_111923075_ENST00000377617_TRIM37_chr17_57079075_ENST00000393066_length(transcript)=3627nt_BP=3160nt
ACCCCCGAGAAAGCAACCCAGCGCGCCGCCCGCTCCTCACGTGTCCCTCCCGGCCCCGGGGCCACCTCACGTTCTGCTTCCGTCTGACCC
CTCCGACTTCCGGTAAAGAGTCCCTATCCGCACCTCCGCTCCCACCCGGCGCCTCGGCGCGCCCGCCCTCCGATGCGCTCAGCGGCCGCA
GCTCCTCGGAGTCCCGCGGTGGCCACCGAGTCTCGCCGCTTCGCCGCAGCCAGGTGGCCCGGGTGGCGCTCGCTCCAGCGGCCGGCGCGG
CGGAGCGGGCGGGGCGGCGGTGGCGCGGCCCCGGGACCGTATCCCTCCGCCGCCCCTCCCCCGCCCGGCCCCGGCCCCCCTCCCTCCCGG
CAGAGCTCGCCTCCCTCCGCCTCAGACTGTTTTGGTAGCAACGGCAACGGCGGCGGCGCGTTTCGGCCCGGCTCCCGGCGGCTCCTTGGT
CTCGGCGGGCCTCCCCGCCCCTTCGTCGTCCTCCTTCTCCCCCTCGCCAGCCCGGGCGCCCCTCCGGCCGCGCCAACCCGCGCCTCCCCG
CTCGGCGCCCGCGCGTCCCCGCCGCGTTCCGGCGTCTCCTTGGCGCGCCCGGCTCCCGGCTGTCCCCGCCCGGCGTGCGAGCCGGTGTAT
GGGCCCCTCACCATGTCGCTGAAGCCCCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAACAGCAGCAGCAGCAGCAGCAG
CAGCAGCCGCCGCCCGCGGCTGCCAATGTCCGCAAGCCCGGCGGCAGCGGCCTTCTAGCGTCGCCCGCCGCCGCGCCTTCGCCGTCCTCG
TCCTCGGTCTCCTCGTCCTCGGCCACGGCTCCCTCCTCGGTGGTCGCGGCGACCTCCGGCGGCGGGAGGCCCGGCCTGGGCAGAGGTCGA
AACAGTAACAAAGGACTGCCTCAGTCTACGATTTCTTTTGATGGAATCTATGCAAATATGAGGATGGTTCATATACTTACATCAGTTGTT
GGCTCCAAATGTGAAGTACAAGTGAAAAATGGAGGTATATATGAAGGAGTTTTTAAAACTTACAGTCCGAAGTGTGATTTGGTACTTGAT
GCCGCACATGAGAAAAGTACAGAATCCAGTTCGGGGCCGAAACGTGAAGAAATAATGGAGAGTATTTTGTTCAAATGTTCAGACTTTGTT
GTGGTACAGTTTAAAGATATGGACTCCAGTTATGCAAAAAGAGATGCTTTTACTGACTCTGCTATCAGTGCTAAAGTGAATGGCGAACAC
AAAGAGAAGGACCTGGAGCCCTGGGATGCAGGTGAACTCACAGCCAATGAGGAACTTGAGGCTTTGGAAAATGACGTATCTAATGGATGG
GATCCCAATGATATGTTTCGATATAATGAAGAAAATTATGGTGTAGTGTCTACGTATGATAGCAGTTTATCTTCGTATACAGTGCCCTTA
GAAAGAGATAACTCAGAAGAATTTTTAAAACGGGAAGCAAGGGCAAACCAGTTAGCAGAAGAAATTGAGTCAAGTGCCCAGTACAAAGCT
CGAGTGGCCCTGGAAAATGATGATAGGAGTGAGGAAGAAAAATACACAGCAGTTCAGAGAAATTCCAGTGAACGTGAGGGGCACAGCATA
AACACTAGGGAAAATAAATATATTCCTCCTGGACAAAGAAATAGAGAAGTCATATCCTGGGGAAGTGGGAGACAGAATTCACCGCGTATG
GGCCAGCCTGGATCGGGCTCCATGCCATCAAGATCCACTTCTCACACTTCAGATTTCAACCCGAATTCTGGTTCAGACCAAAGAGTAGTT
AATGGAGGTGTTCCCTGGCCATCGCCTTGCCCATCTCCTTCCTCTCGCCCACCTTCTCGCTACCAGTCAGGTCCCAACTCTCTTCCACCT
CGGGCAGCCACCCCTACACGGCCGCCCTCCAGGCCCCCCTCGCGGCCATCCAGACCCCCGTCTCACCCCTCTGCTCATGGTTCTCCAGCT
CCTGTCTCTACTATGCCTAAACGCATGTCTTCAGAAGGGCCTCCAAGGATGTCCCCAAAGGCCCAGCGACATCCTCGAAATCACAGAGTT
TCTGCTGGGAGGGGTTCCATATCCAGTGGCCTAGAATTTGTATCCCACAACCCACCCAGTGAAGCAGCTACTCCTCCAGTAGCAAGGACC
AGTCCCTCGGGGGGAACGTGGTCATCAGTGGTCAGTGGGGTTCCAAGATTATCCCCTAAAACTCATAGACCCAGGTCTCCCAGACAGAAC
AGTATTGGAAATACCCCCAGTGGGCCAGTTCTTGCTTCTCCCCAAGCTGGTATTATTCCAACTGAAGCTGTTGCCATGCCTATTCCAGCT
GCATCTCCTACGCCTGCTAGTCCTGCATCGAACAGAGCTGTTACCCCTTCTAGTGAGGCTAAAGATTCCAGGCTTCAAGATCAGAGGCAG
AACTCTCCTGCAGGGAATAAAGAAAATATTAAACCCAATGAAACATCACCTAGCTTCTCAAAAGCTGAAAACAAAGGTATATCACCAGTT
GTTTCTGAACATAGAAAACAGATTGATGATTTAAAGAAATTTAAGAATGATTTTAGGTTACAGCCAAGTTCTACTTCTGAATCTATGGAT
CAACTACTAAACAAAAATAGAGAGGGAGAAAAATCAAGAGATTTGATCAAAGACAAAATTGAACCAAGTGCTAAGGATTCTTTCATTGAA
AATAGCAGCAGCAACTGTACCAGTGGCAGCAGCAAGCCGAATAGCCCCAGCATTTCCCCTTCAATACTTAGTAACACGGAGCACAAGAGG
GGACCTGAGGTCACTTCCCAAGGGGTTCAGACTTCCAGCCCAGCATGTAAACAAGAGAAAGACGATAAGGAAGAGAAGAAAGACGCAGCT
GAGCAAGTTAGGAAATCAACATTGAATCCCAATGCAAAGGAGTTCAACCCACGTTCCTTCTCTCAGCCAAAGCCTTCTACTACCCCAACT
TCACCTCGGCCTCAAGCACAACCTAGCCCATCTATGGTGGGTCATCAACAGCCAACTCCAGTTTATACTCAGCCTGTTTGTTTTGCACCA
AATATGATGTATCCAGTCCCAGTGAGCCCAGGCGTGCAACCTTTATACCCAATACCTATGACGCCCATGCCAGTGAATCAAGCCAAGACA
TATAGAGCAGGAATGAGTAGCGACAGTGACATTGAATGTGACACTGAGAATGAGGAGCAGGAAGAGCATACCAGTGTGGGCGGGTTTCAC
GACTCCTTCATGGTCATGACACAGCCCCCGGATGAAGATACACATTCCAGTTTTCCTGATGGTGAACAAATAGGCCCTGAAGATCTCAGC
TTCAATACAGATGAAAATAGTGGAAGATAATTTGATTTGAAACTGACACTGCACCTGATGGGTTAACAAGATCTAGGCTTCAGAAGGTGA
CAGATATGAGTGAGGACCATGTGTGGGGCAAAGCCTCAGAATGATGAAAAGGTTCCGGCACTATAGTTGGGGCCATGTTGACTCCTTTTC
AACCATTTGTCACAGACGTGAGAAGAAGAAATGACTTCAAAATCAAGAGAAAACAAATACTGAAAGTCTCTACTTACATCCAAATTTTAA

>8437_8437_14_ATXN2-TRIM37_ATXN2_chr12_111923075_ENST00000377617_TRIM37_chr17_57079075_ENST00000393066_length(amino acids)=1065AA_BP=999
MRSAAAAPRSPAVATESRRFAAARWPGWRSLQRPARRSGRGGGGAAPGPYPSAAPPPPGPGPPPSRQSSPPSASDCFGSNGNGGGAFRPG
SRRLLGLGGPPRPFVVLLLPLASPGAPPAAPTRASPLGARASPPRSGVSLARPAPGCPRPACEPVYGPLTMSLKPQQQQQQQQQQQQQQQ
QQQQQQQQPPPAAANVRKPGGSGLLASPAAAPSPSSSSVSSSSATAPSSVVAATSGGGRPGLGRGRNSNKGLPQSTISFDGIYANMRMVH
ILTSVVGSKCEVQVKNGGIYEGVFKTYSPKCDLVLDAAHEKSTESSSGPKREEIMESILFKCSDFVVVQFKDMDSSYAKRDAFTDSAISA
KVNGEHKEKDLEPWDAGELTANEELEALENDVSNGWDPNDMFRYNEENYGVVSTYDSSLSSYTVPLERDNSEEFLKREARANQLAEEIES
SAQYKARVALENDDRSEEEKYTAVQRNSSEREGHSINTRENKYIPPGQRNREVISWGSGRQNSPRMGQPGSGSMPSRSTSHTSDFNPNSG
SDQRVVNGGVPWPSPCPSPSSRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSAHGSPAPVSTMPKRMSSEGPPRMSPKAQRH
PRNHRVSAGRGSISSGLEFVSHNPPSEAATPPVARTSPSGGTWSSVVSGVPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEAV
AMPIPAASPTPASPASNRAVTPSSEAKDSRLQDQRQNSPAGNKENIKPNETSPSFSKAENKGISPVVSEHRKQIDDLKKFKNDFRLQPSS
TSESMDQLLNKNREGEKSRDLIKDKIEPSAKDSFIENSSSNCTSGSSKPNSPSISPSILSNTEHKRGPEVTSQGVQTSSPACKQEKDDKE
EKKDAAEQVRKSTLNPNAKEFNPRSFSQPKPSTTPTSPRPQAQPSPSMVGHQQPTPVYTQPVCFAPNMMYPVPVSPGVQPLYPIPMTPMP

--------------------------------------------------------------
>8437_8437_15_ATXN2-TRIM37_ATXN2_chr12_111923075_ENST00000535949_TRIM37_chr17_57079075_ENST00000262294_length(transcript)=3632nt_BP=2257nt
CCCGAGAAAGCAACCCAGCGCGCCGCCCGCTCCTCACGTGTCCCTCCCGGCCCCGGGGCCACCTCACGTTCTGCTTCCGTCTGACCCCTC
CGACTTCCGATTTCTTTTGATGGAATCTATGCAAATATGAGGATGGTTCATATACTTACATCAGTTGTTTGTGATTTGGTACTTGATGCC
GCACATGAGAAAAGTACAGAATCCAGTTCGGGGCCGAAACGTGAAGAAATAATGGAGAGTATTTTGTTCAAATGTTCAGACTTTGTTGTG
GTACAGTTTAAAGATATGGACTCCAGTTATGCAAAAAGAGATGCTTTTACTGACTCTGCTATCAGTGCTAAAGTGAATGGCGAACACAAA
GAGAAGGACCTGGAGCCCTGGGATGCAGGTGAACTCACAGCCAATGAGGAACTTGAGGCTTTGGAAAATGACGTATCTAATGGATGGGAT
CCCAATGATATGTTTCGATATAATGAAGAAAATTATGGTGTAGTGTCTACGTATGATAGCAGTTTATCTTCGTATACAGTGCCCTTAGAA
AGAGATAACTCAGAAGAATTTTTAAAACGGGAAGCAAGGGCAAACCAGTTAGCAGAAGAAATTGAGTCAAGTGCCCAGTACAAAGCTCGA
GTGGCCCTGGAAAATGATGATAGGAGTGAGGAAGAAAAATACACAGCAGTTCAGAGAAATTCCAGTGAACGTGAGGGGCACAGCATAAAC
ACTAGGGAAAATAAATATATTCCTCCTGGACAAAGAAATAGAGAAGTCATATCCTGGGGAAGTGGGAGACAGAATTCACCGCGTATGGGC
CAGCCTGGATCGGGCTCCATGCCATCAAGATCCACTTCTCACACTTCAGATTTCAACCCGAATTCTGGTTCAGACCAAAGAGTAGTTAAT
GGAGGTGTTCCCTGGCCATCGCCTTGCCCATCTCCTTCCTCTCGCCCACCTTCTCGCTACCAGTCAGGTCCCAACTCTCTTCCACCTCGG
GCAGCCACCCCTACACGGCCGCCCTCCAGGCCCCCCTCGCGGCCATCCAGACCCCCGTCTCACCCCTCTGCTCATGGTTCTCCAGCTCCT
GTCTCTACTATGCCTAAACGCATGTCTTCAGAAGGGCCTCCAAGGATGTCCCCAAAGGCCCAGCGACATCCTCGAAATCACAGAGTTTCT
GCTGGGAGGGGTTCCATATCCAGTGGCCTAGAATTTGTATCCCACAACCCACCCAGTGAAGCAGCTACTCCTCCAGTAGCAAGGACCAGT
CCCTCGGGGGGAACGTGGTCATCAGTGGTCAGTGGGGTTCCAAGATTATCCCCTAAAACTCATAGACCCAGGTCTCCCAGACAGAACAGT
ATTGGAAATACCCCCAGTGGGCCAGTTCTTGCTTCTCCCCAAGCTGGTATTATTCCAACTGAAGCTGTTGCCATGCCTATTCCAGCTGCA
TCTCCTACGCCTGCTAGTCCTGCATCGAACAGAGCTGTTACCCCTTCTAGTGAGGCTAAAGATTCCAGGCTTCAAGATCAGAGGCAGAAC
TCTCCTGCAGGGAATAAAGAAAATATTAAACCCAATGAAACATCACCTAGCTTCTCAAAAGCTGAAAACAAAGGTATATCACCAGTTGTT
TCTGAACATAGAAAACAGATTGATGATTTAAAGAAATTTAAGAATGATTTTAGGTTACAGCCAAGTTCTACTTCTGAATCTATGGATCAA
CTACTAAACAAAAATAGAGAGGGAGAAAAATCAAGAGATTTGATCAAAGACAAAATTGAACCAAGTGCTAAGGATTCTTTCATTGAAAAT
AGCAGCAGCAACTGTACCAGTGGCAGCAGCAAGCCGAATAGCCCCAGCATTTCCCCTTCAATACTTAGTAACACGGAGCACAAGAGGGGA
CCTGAGGTCACTTCCCAAGGGGTTCAGACTTCCAGCCCAGCATGTAAACAAGAGAAAGACGATAAGGAAGAGAAGAAAGACGCAGCTGAG
CAAGTTAGGAAATCAACATTGAATCCCAATGCAAAGGAGTTCAACCCACGTTCCTTCTCTCAGCCAAAGCCTTCTACTACCCCAACTTCA
CCTCGGCCTCAAGCACAACCTAGCCCATCTATGGTGGGTCATCAACAGCCAACTCCAGTTTATACTCAGCCTGTTTGTTTTGCACCAAAT
ATGATGTATCCAGTCCCAGTGAGCCCAGGCGTGCAACCTTTATACCCAATACCTATGACGCCCATGCCAGTGAATCAAGCCAAGACATAT
AGAGCAGGAATGAGTAGCGACAGTGACATTGAATGTGACACTGAGAATGAGGAGCAGGAAGAGCATACCAGTGTGGGCGGGTTTCACGAC
TCCTTCATGGTCATGACACAGCCCCCGGATGAAGATACACATTCCAGTTTTCCTGATGGTGAACAAATAGGCCCTGAAGATCTCAGCTTC
AATACAGATGAAAATAGTGGAAGGTAATTGCCAAATCAAGAGAACTGACTTGCAAGCTACCTTGACCCTGAATTTTGCTGTAGTTGGTGC
TCAAATTTGTCATCAGTCAGATAATCAGATTTGGTCTTATTTCTTCATTATCTCGACCTGAAATAGTAATTTGGAAACTGTTGGAAGGTG
GCACAGTTTAGTCTAAGACAGCAGTAGTACATGGGAAAAACAGTATGGGAAGAGTTCTTTGTAATGTAAGGAAATAACAATGTAGTTCTC
TATTAATTTAGCAAATTTGTACATTCACAAAAGGCAGTTTGTCTACTACAGCAGAAGGCTGGTTAACTGCCAGAAAATGTACCTCCAGGC
CCTGCATGCCGTCAGTAACCCGCCCGGCATTGGTGCTCTACTGTCTTTGGCTAGAGCTTAGTTGTGTTTAAATAATCATCTTTATATTTG
GGGTTTTAATTACAGTTCCATTAGTGCCTGTAGATTAGTGAACAGAAAATTGCTTTGGAAGAGATTCTGCCCTGTAGACACTATGTGAAT
AACTGAAGTAACACTAGACTGAATCTCCTTTTTGGAGTATGTATCTTCTCTCACTTGTTCAAGTACAGGCACACTGTTCAACCGCATGGT
ATCTTTCTGTTGTGTGACTTCTACAAATGTAATTTTAAATGAAATTAAGTTAACATGGATTCATTACGTTCCTGGCCCTGTAGACACGTG
TAAGATTATTTAAAATTCTTTCATTTTTTTCTGCCTCTTACTATACGACTGTAGTGCAACAAATATTTTAAAGCCCCCTTTTCTTCTTTA
TTTTCATTAGTTGTACATTGATTTCAGTGTCAACACATTTAAAGATTCATTCATGTTGCACAGTGGCTTACATGAACGTGAAACTGTGAT
ATAAGGTTTTCTTTCATACTCATAATTAGCCCAAAACAGTTGCCAAACTTTGCCATTGTGCTCCTGCATTTGTGTTTGAGCTGCTATATA
TTTGTGGAAATTACACTGAAAGTTGACTAAGAGACTATTGAAAAAGCATGAATAATTAAATATACATGTGAGAGACATCTCATCTGCTGT
ATTTTACTTAGTGAATATTGTTCACTCTTCCGTGTCTGATGTCTTGCTGAATGCTGTGACTCATAGTTTACTTTTGTTCAAAATAGTTTG

>8437_8437_15_ATXN2-TRIM37_ATXN2_chr12_111923075_ENST00000535949_TRIM37_chr17_57079075_ENST00000262294_length(amino acids)=776AA_BP=710
MRMVHILTSVVCDLVLDAAHEKSTESSSGPKREEIMESILFKCSDFVVVQFKDMDSSYAKRDAFTDSAISAKVNGEHKEKDLEPWDAGEL
TANEELEALENDVSNGWDPNDMFRYNEENYGVVSTYDSSLSSYTVPLERDNSEEFLKREARANQLAEEIESSAQYKARVALENDDRSEEE
KYTAVQRNSSEREGHSINTRENKYIPPGQRNREVISWGSGRQNSPRMGQPGSGSMPSRSTSHTSDFNPNSGSDQRVVNGGVPWPSPCPSP
SSRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSAHGSPAPVSTMPKRMSSEGPPRMSPKAQRHPRNHRVSAGRGSISSGLEF
VSHNPPSEAATPPVARTSPSGGTWSSVVSGVPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEAVAMPIPAASPTPASPASNRA
VTPSSEAKDSRLQDQRQNSPAGNKENIKPNETSPSFSKAENKGISPVVSEHRKQIDDLKKFKNDFRLQPSSTSESMDQLLNKNREGEKSR
DLIKDKIEPSAKDSFIENSSSNCTSGSSKPNSPSISPSILSNTEHKRGPEVTSQGVQTSSPACKQEKDDKEEKKDAAEQVRKSTLNPNAK
EFNPRSFSQPKPSTTPTSPRPQAQPSPSMVGHQQPTPVYTQPVCFAPNMMYPVPVSPGVQPLYPIPMTPMPVNQAKTYRAGMSSDSDIEC

--------------------------------------------------------------
>8437_8437_16_ATXN2-TRIM37_ATXN2_chr12_111923075_ENST00000535949_TRIM37_chr17_57079075_ENST00000393066_length(transcript)=2724nt_BP=2257nt
CCCGAGAAAGCAACCCAGCGCGCCGCCCGCTCCTCACGTGTCCCTCCCGGCCCCGGGGCCACCTCACGTTCTGCTTCCGTCTGACCCCTC
CGACTTCCGATTTCTTTTGATGGAATCTATGCAAATATGAGGATGGTTCATATACTTACATCAGTTGTTTGTGATTTGGTACTTGATGCC
GCACATGAGAAAAGTACAGAATCCAGTTCGGGGCCGAAACGTGAAGAAATAATGGAGAGTATTTTGTTCAAATGTTCAGACTTTGTTGTG
GTACAGTTTAAAGATATGGACTCCAGTTATGCAAAAAGAGATGCTTTTACTGACTCTGCTATCAGTGCTAAAGTGAATGGCGAACACAAA
GAGAAGGACCTGGAGCCCTGGGATGCAGGTGAACTCACAGCCAATGAGGAACTTGAGGCTTTGGAAAATGACGTATCTAATGGATGGGAT
CCCAATGATATGTTTCGATATAATGAAGAAAATTATGGTGTAGTGTCTACGTATGATAGCAGTTTATCTTCGTATACAGTGCCCTTAGAA
AGAGATAACTCAGAAGAATTTTTAAAACGGGAAGCAAGGGCAAACCAGTTAGCAGAAGAAATTGAGTCAAGTGCCCAGTACAAAGCTCGA
GTGGCCCTGGAAAATGATGATAGGAGTGAGGAAGAAAAATACACAGCAGTTCAGAGAAATTCCAGTGAACGTGAGGGGCACAGCATAAAC
ACTAGGGAAAATAAATATATTCCTCCTGGACAAAGAAATAGAGAAGTCATATCCTGGGGAAGTGGGAGACAGAATTCACCGCGTATGGGC
CAGCCTGGATCGGGCTCCATGCCATCAAGATCCACTTCTCACACTTCAGATTTCAACCCGAATTCTGGTTCAGACCAAAGAGTAGTTAAT
GGAGGTGTTCCCTGGCCATCGCCTTGCCCATCTCCTTCCTCTCGCCCACCTTCTCGCTACCAGTCAGGTCCCAACTCTCTTCCACCTCGG
GCAGCCACCCCTACACGGCCGCCCTCCAGGCCCCCCTCGCGGCCATCCAGACCCCCGTCTCACCCCTCTGCTCATGGTTCTCCAGCTCCT
GTCTCTACTATGCCTAAACGCATGTCTTCAGAAGGGCCTCCAAGGATGTCCCCAAAGGCCCAGCGACATCCTCGAAATCACAGAGTTTCT
GCTGGGAGGGGTTCCATATCCAGTGGCCTAGAATTTGTATCCCACAACCCACCCAGTGAAGCAGCTACTCCTCCAGTAGCAAGGACCAGT
CCCTCGGGGGGAACGTGGTCATCAGTGGTCAGTGGGGTTCCAAGATTATCCCCTAAAACTCATAGACCCAGGTCTCCCAGACAGAACAGT
ATTGGAAATACCCCCAGTGGGCCAGTTCTTGCTTCTCCCCAAGCTGGTATTATTCCAACTGAAGCTGTTGCCATGCCTATTCCAGCTGCA
TCTCCTACGCCTGCTAGTCCTGCATCGAACAGAGCTGTTACCCCTTCTAGTGAGGCTAAAGATTCCAGGCTTCAAGATCAGAGGCAGAAC
TCTCCTGCAGGGAATAAAGAAAATATTAAACCCAATGAAACATCACCTAGCTTCTCAAAAGCTGAAAACAAAGGTATATCACCAGTTGTT
TCTGAACATAGAAAACAGATTGATGATTTAAAGAAATTTAAGAATGATTTTAGGTTACAGCCAAGTTCTACTTCTGAATCTATGGATCAA
CTACTAAACAAAAATAGAGAGGGAGAAAAATCAAGAGATTTGATCAAAGACAAAATTGAACCAAGTGCTAAGGATTCTTTCATTGAAAAT
AGCAGCAGCAACTGTACCAGTGGCAGCAGCAAGCCGAATAGCCCCAGCATTTCCCCTTCAATACTTAGTAACACGGAGCACAAGAGGGGA
CCTGAGGTCACTTCCCAAGGGGTTCAGACTTCCAGCCCAGCATGTAAACAAGAGAAAGACGATAAGGAAGAGAAGAAAGACGCAGCTGAG
CAAGTTAGGAAATCAACATTGAATCCCAATGCAAAGGAGTTCAACCCACGTTCCTTCTCTCAGCCAAAGCCTTCTACTACCCCAACTTCA
CCTCGGCCTCAAGCACAACCTAGCCCATCTATGGTGGGTCATCAACAGCCAACTCCAGTTTATACTCAGCCTGTTTGTTTTGCACCAAAT
ATGATGTATCCAGTCCCAGTGAGCCCAGGCGTGCAACCTTTATACCCAATACCTATGACGCCCATGCCAGTGAATCAAGCCAAGACATAT
AGAGCAGGAATGAGTAGCGACAGTGACATTGAATGTGACACTGAGAATGAGGAGCAGGAAGAGCATACCAGTGTGGGCGGGTTTCACGAC
TCCTTCATGGTCATGACACAGCCCCCGGATGAAGATACACATTCCAGTTTTCCTGATGGTGAACAAATAGGCCCTGAAGATCTCAGCTTC
AATACAGATGAAAATAGTGGAAGATAATTTGATTTGAAACTGACACTGCACCTGATGGGTTAACAAGATCTAGGCTTCAGAAGGTGACAG
ATATGAGTGAGGACCATGTGTGGGGCAAAGCCTCAGAATGATGAAAAGGTTCCGGCACTATAGTTGGGGCCATGTTGACTCCTTTTCAAC
CATTTGTCACAGACGTGAGAAGAAGAAATGACTTCAAAATCAAGAGAAAACAAATACTGAAAGTCTCTACTTACATCCAAATTTTAAAAA

>8437_8437_16_ATXN2-TRIM37_ATXN2_chr12_111923075_ENST00000535949_TRIM37_chr17_57079075_ENST00000393066_length(amino acids)=776AA_BP=710
MRMVHILTSVVCDLVLDAAHEKSTESSSGPKREEIMESILFKCSDFVVVQFKDMDSSYAKRDAFTDSAISAKVNGEHKEKDLEPWDAGEL
TANEELEALENDVSNGWDPNDMFRYNEENYGVVSTYDSSLSSYTVPLERDNSEEFLKREARANQLAEEIESSAQYKARVALENDDRSEEE
KYTAVQRNSSEREGHSINTRENKYIPPGQRNREVISWGSGRQNSPRMGQPGSGSMPSRSTSHTSDFNPNSGSDQRVVNGGVPWPSPCPSP
SSRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSAHGSPAPVSTMPKRMSSEGPPRMSPKAQRHPRNHRVSAGRGSISSGLEF
VSHNPPSEAATPPVARTSPSGGTWSSVVSGVPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEAVAMPIPAASPTPASPASNRA
VTPSSEAKDSRLQDQRQNSPAGNKENIKPNETSPSFSKAENKGISPVVSEHRKQIDDLKKFKNDFRLQPSSTSESMDQLLNKNREGEKSR
DLIKDKIEPSAKDSFIENSSSNCTSGSSKPNSPSISPSILSNTEHKRGPEVTSQGVQTSSPACKQEKDDKEEKKDAAEQVRKSTLNPNAK
EFNPRSFSQPKPSTTPTSPRPQAQPSPSMVGHQQPTPVYTQPVCFAPNMMYPVPVSPGVQPLYPIPMTPMPVNQAKTYRAGMSSDSDIEC

--------------------------------------------------------------
>8437_8437_17_ATXN2-TRIM37_ATXN2_chr12_111923075_ENST00000608853_TRIM37_chr17_57079075_ENST00000262294_length(transcript)=4209nt_BP=2834nt
TCCCCCGCCCGGCCCCGGCCCCCCTCCCTCCCGGCAGAGCTCGCCTCCCTCCGCCTCAGACTGTTTTGGTAGCAACGGCAACGGCGGCGG
CGCGTTTCGGCCCGGCTCCCGGCGGCTCCTTGGTCTCGGCGGGCCTCCCCGCCCCTTCGTCGTCCTCCTTCTCCCCCTCGCCAGCCCGGG
CGCCCCTCCGGCCGCGCCAACCCGCGCCTCCCCGCTCGGCGCCCGCGCGTCCCCGCCGCGTTCCGGCGTCTCCTTGGCGCGCCCGGCTCC
CGGCTGTCCCCGCCCGGCGTGCGAGCCGGTGTATGGGCCCCTCACCATGTCGCTGAAGCCCCAGCAGCAGCAGCAGCAGCAGCAGCAGCA
GCAGCAGCAGCAACAGCAGCAGCAGCAGCAGCAGCAGCAGCCGCCGCCCGCGGCTGCCAATGTCCGCAAGCCCGGCGGCAGCGGCCTTCT
AGCGTCGCCCGCCGCCGCGCCTTCGCCGTCCTCGTCCTCGGTCTCCTCGTCCTCGGCCACGGCTCCCTCCTCGGTGGTCGCGGCGACCTC
CGGCGGCGGGAGGCCCGGCCTGGGCAGAGGTCGAAACAGTAACAAAGGACTGCCTCAGTCTACGATTTCTTTTGATGGAATCTATGCAAA
TATGAGGATGGTTCATATACTTACATCAGTTGTTGGCTCCAAATGTGAAGTACAAGTGAAAAATGGAGGTATATATGAAGGAGTTTTTAA
AACTTACAGTCCGAAGTGTGATTTGGTACTTGATGCCGCACATGAGAAAAGTACAGAATCCAGTTCGGGGCCGAAACGTGAAGAAATAAT
GGAGAGTATTTTGTTCAAATGTTCAGACTTTGTTGTGGTACAGTTTAAAGATATGGACTCCAGTTATGCAAAAAGAGATGCTTTTACTGA
CTCTGCTATCAGTGCTAAAGTGAATGGCGAACACAAAGAGAAGGACCTGGAGCCCTGGGATGCAGGTGAACTCACAGCCAATGAGGAACT
TGAGGCTTTGGAAAATGACGTATCTAATGGATGGGATCCCAATGATATGTTTCGATATAATGAAGAAAATTATGGTGTAGTGTCTACGTA
TGATAGCAGTTTATCTTCGTATACAGTGCCCTTAGAAAGAGATAACTCAGAAGAATTTTTAAAACGGGAAGCAAGGGCAAACCAGTTAGC
AGAAGAAATTGAGTCAAGTGCCCAGTACAAAGCTCGAGTGGCCCTGGAAAATGATGATAGGAGTGAGGAAGAAAAATACACAGCAGTTCA
GAGAAATTCCAGTGAACGTGAGGGGCACAGCATAAACACTAGGGAAAATAAATATATTCCTCCTGGACAAAGAAATAGAGAAGTCATATC
CTGGGGAAGTGGGAGACAGAATTCACCGCGTATGGGCCAGCCTGGATCGGGCTCCATGCCATCAAGATCCACTTCTCACACTTCAGATTT
CAACCCGAATTCTGGTTCAGACCAAAGAGTAGTTAATGGAGGTGTTCCCTGGCCATCGCCTTGCCCATCTCCTTCCTCTCGCCCACCTTC
TCGCTACCAGTCAGGTCCCAACTCTCTTCCACCTCGGGCAGCCACCCCTACACGGCCGCCCTCCAGGCCCCCCTCGCGGCCATCCAGACC
CCCGTCTCACCCCTCTGCTCATGGTTCTCCAGCTCCTGTCTCTACTATGCCTAAACGCATGTCTTCAGAAGGGCCTCCAAGGATGTCCCC
AAAGGCCCAGCGACATCCTCGAAATCACAGAGTTTCTGCTGGGAGGGGTTCCATATCCAGTGGCCTAGAATTTGTATCCCACAACCCACC
CAGTGAAGCAGCTACTCCTCCAGTAGCAAGGACCAGTCCCTCGGGGGGAACGTGGTCATCAGTGGTCAGTGGGGTTCCAAGATTATCCCC
TAAAACTCATAGACCCAGGTCTCCCAGACAGAACAGTATTGGAAATACCCCCAGTGGGCCAGTTCTTGCTTCTCCCCAAGCTGGTATTAT
TCCAACTGAAGCTGTTGCCATGCCTATTCCAGCTGCATCTCCTACGCCTGCTAGTCCTGCATCGAACAGAGCTGTTACCCCTTCTAGTGA
GGCTAAAGATTCCAGGCTTCAAGATCAGAGGCAGAACTCTCCTGCAGGGAATAAAGAAAATATTAAACCCAATGAAACATCACCTAGCTT
CTCAAAAGCTGAAAACAAAGGTATATCACCAGTTGTTTCTGAACATAGAAAACAGATTGATGATTTAAAGAAATTTAAGAATGATTTTAG
GTTACAGCCAAGTTCTACTTCTGAATCTATGGATCAACTACTAAACAAAAATAGAGAGGGAGAAAAATCAAGAGATTTGATCAAAGACAA
AATTGAACCAAGTGCTAAGGATTCTTTCATTGAAAATAGCAGCAGCAACTGTACCAGTGGCAGCAGCAAGCCGAATAGCCCCAGCATTTC
CCCTTCAATACTTAGTAACACGGAGCACAAGAGGGGACCTGAGGTCACTTCCCAAGGGGTTCAGACTTCCAGCCCAGCATGTAAACAAGA
GAAAGACGATAAGGAAGAGAAGAAAGACGCAGCTGAGCAAGTTAGGAAATCAACATTGAATCCCAATGCAAAGGAGTTCAACCCACGTTC
CTTCTCTCAGCCAAAGCCTTCTACTACCCCAACTTCACCTCGGCCTCAAGCACAACCTAGCCCATCTATGGTGGGTCATCAACAGCCAAC
TCCAGTTTATACTCAGCCTGTTTGTTTTGCACCAAATATGATGTATCCAGTCCCAGTGAGCCCAGGCGTGCAACCTTTATACCCAATACC
TATGACGCCCATGCCAGTGAATCAAGCCAAGACATATAGAGCAGGAATGAGTAGCGACAGTGACATTGAATGTGACACTGAGAATGAGGA
GCAGGAAGAGCATACCAGTGTGGGCGGGTTTCACGACTCCTTCATGGTCATGACACAGCCCCCGGATGAAGATACACATTCCAGTTTTCC
TGATGGTGAACAAATAGGCCCTGAAGATCTCAGCTTCAATACAGATGAAAATAGTGGAAGGTAATTGCCAAATCAAGAGAACTGACTTGC
AAGCTACCTTGACCCTGAATTTTGCTGTAGTTGGTGCTCAAATTTGTCATCAGTCAGATAATCAGATTTGGTCTTATTTCTTCATTATCT
CGACCTGAAATAGTAATTTGGAAACTGTTGGAAGGTGGCACAGTTTAGTCTAAGACAGCAGTAGTACATGGGAAAAACAGTATGGGAAGA
GTTCTTTGTAATGTAAGGAAATAACAATGTAGTTCTCTATTAATTTAGCAAATTTGTACATTCACAAAAGGCAGTTTGTCTACTACAGCA
GAAGGCTGGTTAACTGCCAGAAAATGTACCTCCAGGCCCTGCATGCCGTCAGTAACCCGCCCGGCATTGGTGCTCTACTGTCTTTGGCTA
GAGCTTAGTTGTGTTTAAATAATCATCTTTATATTTGGGGTTTTAATTACAGTTCCATTAGTGCCTGTAGATTAGTGAACAGAAAATTGC
TTTGGAAGAGATTCTGCCCTGTAGACACTATGTGAATAACTGAAGTAACACTAGACTGAATCTCCTTTTTGGAGTATGTATCTTCTCTCA
CTTGTTCAAGTACAGGCACACTGTTCAACCGCATGGTATCTTTCTGTTGTGTGACTTCTACAAATGTAATTTTAAATGAAATTAAGTTAA
CATGGATTCATTACGTTCCTGGCCCTGTAGACACGTGTAAGATTATTTAAAATTCTTTCATTTTTTTCTGCCTCTTACTATACGACTGTA
GTGCAACAAATATTTTAAAGCCCCCTTTTCTTCTTTATTTTCATTAGTTGTACATTGATTTCAGTGTCAACACATTTAAAGATTCATTCA
TGTTGCACAGTGGCTTACATGAACGTGAAACTGTGATATAAGGTTTTCTTTCATACTCATAATTAGCCCAAAACAGTTGCCAAACTTTGC
CATTGTGCTCCTGCATTTGTGTTTGAGCTGCTATATATTTGTGGAAATTACACTGAAAGTTGACTAAGAGACTATTGAAAAAGCATGAAT
AATTAAATATACATGTGAGAGACATCTCATCTGCTGTATTTTACTTAGTGAATATTGTTCACTCTTCCGTGTCTGATGTCTTGCTGAATG

>8437_8437_17_ATXN2-TRIM37_ATXN2_chr12_111923075_ENST00000608853_TRIM37_chr17_57079075_ENST00000262294_length(amino acids)=926AA_BP=860
MARPAPGCPRPACEPVYGPLTMSLKPQQQQQQQQQQQQQQQQQQQQQQQPPPAAANVRKPGGSGLLASPAAAPSPSSSSVSSSSATAPSS
VVAATSGGGRPGLGRGRNSNKGLPQSTISFDGIYANMRMVHILTSVVGSKCEVQVKNGGIYEGVFKTYSPKCDLVLDAAHEKSTESSSGP
KREEIMESILFKCSDFVVVQFKDMDSSYAKRDAFTDSAISAKVNGEHKEKDLEPWDAGELTANEELEALENDVSNGWDPNDMFRYNEENY
GVVSTYDSSLSSYTVPLERDNSEEFLKREARANQLAEEIESSAQYKARVALENDDRSEEEKYTAVQRNSSEREGHSINTRENKYIPPGQR
NREVISWGSGRQNSPRMGQPGSGSMPSRSTSHTSDFNPNSGSDQRVVNGGVPWPSPCPSPSSRPPSRYQSGPNSLPPRAATPTRPPSRPP
SRPSRPPSHPSAHGSPAPVSTMPKRMSSEGPPRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAATPPVARTSPSGGTWSSVVSG
VPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEAVAMPIPAASPTPASPASNRAVTPSSEAKDSRLQDQRQNSPAGNKENIKPN
ETSPSFSKAENKGISPVVSEHRKQIDDLKKFKNDFRLQPSSTSESMDQLLNKNREGEKSRDLIKDKIEPSAKDSFIENSSSNCTSGSSKP
NSPSISPSILSNTEHKRGPEVTSQGVQTSSPACKQEKDDKEEKKDAAEQVRKSTLNPNAKEFNPRSFSQPKPSTTPTSPRPQAQPSPSMV
GHQQPTPVYTQPVCFAPNMMYPVPVSPGVQPLYPIPMTPMPVNQAKTYRAGMSSDSDIECDTENEEQEEHTSVGGFHDSFMVMTQPPDED

--------------------------------------------------------------
>8437_8437_18_ATXN2-TRIM37_ATXN2_chr12_111923075_ENST00000608853_TRIM37_chr17_57079075_ENST00000393066_length(transcript)=3301nt_BP=2834nt
TCCCCCGCCCGGCCCCGGCCCCCCTCCCTCCCGGCAGAGCTCGCCTCCCTCCGCCTCAGACTGTTTTGGTAGCAACGGCAACGGCGGCGG
CGCGTTTCGGCCCGGCTCCCGGCGGCTCCTTGGTCTCGGCGGGCCTCCCCGCCCCTTCGTCGTCCTCCTTCTCCCCCTCGCCAGCCCGGG
CGCCCCTCCGGCCGCGCCAACCCGCGCCTCCCCGCTCGGCGCCCGCGCGTCCCCGCCGCGTTCCGGCGTCTCCTTGGCGCGCCCGGCTCC
CGGCTGTCCCCGCCCGGCGTGCGAGCCGGTGTATGGGCCCCTCACCATGTCGCTGAAGCCCCAGCAGCAGCAGCAGCAGCAGCAGCAGCA
GCAGCAGCAGCAACAGCAGCAGCAGCAGCAGCAGCAGCAGCCGCCGCCCGCGGCTGCCAATGTCCGCAAGCCCGGCGGCAGCGGCCTTCT
AGCGTCGCCCGCCGCCGCGCCTTCGCCGTCCTCGTCCTCGGTCTCCTCGTCCTCGGCCACGGCTCCCTCCTCGGTGGTCGCGGCGACCTC
CGGCGGCGGGAGGCCCGGCCTGGGCAGAGGTCGAAACAGTAACAAAGGACTGCCTCAGTCTACGATTTCTTTTGATGGAATCTATGCAAA
TATGAGGATGGTTCATATACTTACATCAGTTGTTGGCTCCAAATGTGAAGTACAAGTGAAAAATGGAGGTATATATGAAGGAGTTTTTAA
AACTTACAGTCCGAAGTGTGATTTGGTACTTGATGCCGCACATGAGAAAAGTACAGAATCCAGTTCGGGGCCGAAACGTGAAGAAATAAT
GGAGAGTATTTTGTTCAAATGTTCAGACTTTGTTGTGGTACAGTTTAAAGATATGGACTCCAGTTATGCAAAAAGAGATGCTTTTACTGA
CTCTGCTATCAGTGCTAAAGTGAATGGCGAACACAAAGAGAAGGACCTGGAGCCCTGGGATGCAGGTGAACTCACAGCCAATGAGGAACT
TGAGGCTTTGGAAAATGACGTATCTAATGGATGGGATCCCAATGATATGTTTCGATATAATGAAGAAAATTATGGTGTAGTGTCTACGTA
TGATAGCAGTTTATCTTCGTATACAGTGCCCTTAGAAAGAGATAACTCAGAAGAATTTTTAAAACGGGAAGCAAGGGCAAACCAGTTAGC
AGAAGAAATTGAGTCAAGTGCCCAGTACAAAGCTCGAGTGGCCCTGGAAAATGATGATAGGAGTGAGGAAGAAAAATACACAGCAGTTCA
GAGAAATTCCAGTGAACGTGAGGGGCACAGCATAAACACTAGGGAAAATAAATATATTCCTCCTGGACAAAGAAATAGAGAAGTCATATC
CTGGGGAAGTGGGAGACAGAATTCACCGCGTATGGGCCAGCCTGGATCGGGCTCCATGCCATCAAGATCCACTTCTCACACTTCAGATTT
CAACCCGAATTCTGGTTCAGACCAAAGAGTAGTTAATGGAGGTGTTCCCTGGCCATCGCCTTGCCCATCTCCTTCCTCTCGCCCACCTTC
TCGCTACCAGTCAGGTCCCAACTCTCTTCCACCTCGGGCAGCCACCCCTACACGGCCGCCCTCCAGGCCCCCCTCGCGGCCATCCAGACC
CCCGTCTCACCCCTCTGCTCATGGTTCTCCAGCTCCTGTCTCTACTATGCCTAAACGCATGTCTTCAGAAGGGCCTCCAAGGATGTCCCC
AAAGGCCCAGCGACATCCTCGAAATCACAGAGTTTCTGCTGGGAGGGGTTCCATATCCAGTGGCCTAGAATTTGTATCCCACAACCCACC
CAGTGAAGCAGCTACTCCTCCAGTAGCAAGGACCAGTCCCTCGGGGGGAACGTGGTCATCAGTGGTCAGTGGGGTTCCAAGATTATCCCC
TAAAACTCATAGACCCAGGTCTCCCAGACAGAACAGTATTGGAAATACCCCCAGTGGGCCAGTTCTTGCTTCTCCCCAAGCTGGTATTAT
TCCAACTGAAGCTGTTGCCATGCCTATTCCAGCTGCATCTCCTACGCCTGCTAGTCCTGCATCGAACAGAGCTGTTACCCCTTCTAGTGA
GGCTAAAGATTCCAGGCTTCAAGATCAGAGGCAGAACTCTCCTGCAGGGAATAAAGAAAATATTAAACCCAATGAAACATCACCTAGCTT
CTCAAAAGCTGAAAACAAAGGTATATCACCAGTTGTTTCTGAACATAGAAAACAGATTGATGATTTAAAGAAATTTAAGAATGATTTTAG
GTTACAGCCAAGTTCTACTTCTGAATCTATGGATCAACTACTAAACAAAAATAGAGAGGGAGAAAAATCAAGAGATTTGATCAAAGACAA
AATTGAACCAAGTGCTAAGGATTCTTTCATTGAAAATAGCAGCAGCAACTGTACCAGTGGCAGCAGCAAGCCGAATAGCCCCAGCATTTC
CCCTTCAATACTTAGTAACACGGAGCACAAGAGGGGACCTGAGGTCACTTCCCAAGGGGTTCAGACTTCCAGCCCAGCATGTAAACAAGA
GAAAGACGATAAGGAAGAGAAGAAAGACGCAGCTGAGCAAGTTAGGAAATCAACATTGAATCCCAATGCAAAGGAGTTCAACCCACGTTC
CTTCTCTCAGCCAAAGCCTTCTACTACCCCAACTTCACCTCGGCCTCAAGCACAACCTAGCCCATCTATGGTGGGTCATCAACAGCCAAC
TCCAGTTTATACTCAGCCTGTTTGTTTTGCACCAAATATGATGTATCCAGTCCCAGTGAGCCCAGGCGTGCAACCTTTATACCCAATACC
TATGACGCCCATGCCAGTGAATCAAGCCAAGACATATAGAGCAGGAATGAGTAGCGACAGTGACATTGAATGTGACACTGAGAATGAGGA
GCAGGAAGAGCATACCAGTGTGGGCGGGTTTCACGACTCCTTCATGGTCATGACACAGCCCCCGGATGAAGATACACATTCCAGTTTTCC
TGATGGTGAACAAATAGGCCCTGAAGATCTCAGCTTCAATACAGATGAAAATAGTGGAAGATAATTTGATTTGAAACTGACACTGCACCT
GATGGGTTAACAAGATCTAGGCTTCAGAAGGTGACAGATATGAGTGAGGACCATGTGTGGGGCAAAGCCTCAGAATGATGAAAAGGTTCC
GGCACTATAGTTGGGGCCATGTTGACTCCTTTTCAACCATTTGTCACAGACGTGAGAAGAAGAAATGACTTCAAAATCAAGAGAAAACAA

>8437_8437_18_ATXN2-TRIM37_ATXN2_chr12_111923075_ENST00000608853_TRIM37_chr17_57079075_ENST00000393066_length(amino acids)=926AA_BP=860
MARPAPGCPRPACEPVYGPLTMSLKPQQQQQQQQQQQQQQQQQQQQQQQPPPAAANVRKPGGSGLLASPAAAPSPSSSSVSSSSATAPSS
VVAATSGGGRPGLGRGRNSNKGLPQSTISFDGIYANMRMVHILTSVVGSKCEVQVKNGGIYEGVFKTYSPKCDLVLDAAHEKSTESSSGP
KREEIMESILFKCSDFVVVQFKDMDSSYAKRDAFTDSAISAKVNGEHKEKDLEPWDAGELTANEELEALENDVSNGWDPNDMFRYNEENY
GVVSTYDSSLSSYTVPLERDNSEEFLKREARANQLAEEIESSAQYKARVALENDDRSEEEKYTAVQRNSSEREGHSINTRENKYIPPGQR
NREVISWGSGRQNSPRMGQPGSGSMPSRSTSHTSDFNPNSGSDQRVVNGGVPWPSPCPSPSSRPPSRYQSGPNSLPPRAATPTRPPSRPP
SRPSRPPSHPSAHGSPAPVSTMPKRMSSEGPPRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAATPPVARTSPSGGTWSSVVSG
VPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEAVAMPIPAASPTPASPASNRAVTPSSEAKDSRLQDQRQNSPAGNKENIKPN
ETSPSFSKAENKGISPVVSEHRKQIDDLKKFKNDFRLQPSSTSESMDQLLNKNREGEKSRDLIKDKIEPSAKDSFIENSSSNCTSGSSKP
NSPSISPSILSNTEHKRGPEVTSQGVQTSSPACKQEKDDKEEKKDAAEQVRKSTLNPNAKEFNPRSFSQPKPSTTPTSPRPQAQPSPSMV
GHQQPTPVYTQPVCFAPNMMYPVPVSPGVQPLYPIPMTPMPVNQAKTYRAGMSSDSDIECDTENEEQEEHTSVGGFHDSFMVMTQPPDED

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ATXN2-TRIM37


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ATXN2-TRIM37


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ATXN2-TRIM37


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneATXN2C0752121Spinocerebellar Ataxia Type 23CTD_human;GENOMICS_ENGLAND;ORPHANET
HgeneATXN2C0002736Amyotrophic Lateral Sclerosis2CTD_human;ORPHANET
HgeneATXN2C0087012Ataxia, Spinocerebellar2CTD_human
HgeneATXN2C0752120Spinocerebellar Ataxia Type 12CTD_human
HgeneATXN2C0752122Spinocerebellar Ataxia Type 42CTD_human
HgeneATXN2C0752123Spinocerebellar Ataxia Type 52CTD_human
HgeneATXN2C0752124Spinocerebellar Ataxia Type 6 (disorder)2CTD_human
HgeneATXN2C0752125Spinocerebellar Ataxia Type 72CTD_human
HgeneATXN2C0017612Glaucoma, Open-Angle1CTD_human
HgeneATXN2C0036341Schizophrenia1PSYGENET
HgeneATXN2C0271148Secondary Open Angle Glaucoma1CTD_human
HgeneATXN2C0339573Glaucoma, Primary Open Angle1CTD_human
HgeneATXN2C0393554Amyotrophic Lateral Sclerosis With Dementia1CTD_human
HgeneATXN2C0543859Amyotrophic Lateral Sclerosis, Guam Form1CTD_human
TgeneC0524582Mulibrey Nanism11CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
TgeneC0016063Osteitis Fibrosa Disseminata1CTD_human
TgeneC0019209Hepatomegaly1CTD_human
TgeneC0376634Craniofacial Abnormalities1CTD_human
TgeneC2931895Pericardial constriction with growth failure1ORPHANET
TgeneC4704884Fibrocystic Dysplasia of Bone1CTD_human
TgeneC4704885Fibrocartilaginous Dysplasia of Bone1CTD_human