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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ARAP3-DIAPH1 (FusionGDB2 ID:HG64411TG1729)

Fusion Gene Summary for ARAP3-DIAPH1

check button Fusion gene summary
Fusion gene informationFusion gene name: ARAP3-DIAPH1
Fusion gene ID: hg64411tg1729
HgeneTgene
Gene symbol

ARAP3

DIAPH1

Gene ID

64411

1729

Gene nameArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3diaphanous related formin 1
SynonymsCENTD3|DRAG1DFNA1|DIA1|DRF1|LFHL1|SCBMS|hDIA1
Cytomap('ARAP3')('DIAPH1')

5q31.3

5q31.3

Type of geneprotein-codingprotein-coding
Descriptionarf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3ARF-GAP, RHO-GAP, ankyrin repeat and plekstrin homology domains-containing protein 3Arf and Rho GAP adapter protein 3PtdIns(3,4,5)P3-binding proteincentaurin-delta-3phosphoinosprotein diaphanous homolog 1
Modification date2020032720200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000239440, ENST00000508305, 
ENST00000512390, ENST00000513878, 
Fusion gene scores* DoF score3 X 3 X 3=2710 X 8 X 6=480
# samples 310
** MAII scorelog2(3/27*10)=0.15200309344505
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
log2(10/480*10)=-2.26303440583379
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ARAP3 [Title/Abstract] AND DIAPH1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointARAP3(141059112)-DIAPH1(140914000), # samples:1
Anticipated loss of major functional domain due to fusion event.ARAP3-DIAPH1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ARAP3-DIAPH1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ARAP3-DIAPH1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
ARAP3-DIAPH1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
ARAP3-DIAPH1 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
ARAP3-DIAPH1 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across ARAP3 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across DIAPH1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4SKCMTCGA-D9-A3Z1-06AARAP3chr5

141059112

-DIAPH1chr5

140914000

-


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Fusion Gene ORF analysis for ARAP3-DIAPH1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000239440ENST00000494967ARAP3chr5

141059112

-DIAPH1chr5

140914000

-
5CDS-5UTRENST00000508305ENST00000494967ARAP3chr5

141059112

-DIAPH1chr5

140914000

-
Frame-shiftENST00000508305ENST00000253811ARAP3chr5

141059112

-DIAPH1chr5

140914000

-
Frame-shiftENST00000508305ENST00000389054ARAP3chr5

141059112

-DIAPH1chr5

140914000

-
Frame-shiftENST00000508305ENST00000389057ARAP3chr5

141059112

-DIAPH1chr5

140914000

-
Frame-shiftENST00000508305ENST00000398557ARAP3chr5

141059112

-DIAPH1chr5

140914000

-
Frame-shiftENST00000508305ENST00000398562ARAP3chr5

141059112

-DIAPH1chr5

140914000

-
Frame-shiftENST00000508305ENST00000398566ARAP3chr5

141059112

-DIAPH1chr5

140914000

-
Frame-shiftENST00000508305ENST00000518047ARAP3chr5

141059112

-DIAPH1chr5

140914000

-
Frame-shiftENST00000508305ENST00000520569ARAP3chr5

141059112

-DIAPH1chr5

140914000

-
In-frameENST00000239440ENST00000253811ARAP3chr5

141059112

-DIAPH1chr5

140914000

-
In-frameENST00000239440ENST00000389054ARAP3chr5

141059112

-DIAPH1chr5

140914000

-
In-frameENST00000239440ENST00000389057ARAP3chr5

141059112

-DIAPH1chr5

140914000

-
In-frameENST00000239440ENST00000398557ARAP3chr5

141059112

-DIAPH1chr5

140914000

-
In-frameENST00000239440ENST00000398562ARAP3chr5

141059112

-DIAPH1chr5

140914000

-
In-frameENST00000239440ENST00000398566ARAP3chr5

141059112

-DIAPH1chr5

140914000

-
In-frameENST00000239440ENST00000518047ARAP3chr5

141059112

-DIAPH1chr5

140914000

-
In-frameENST00000239440ENST00000520569ARAP3chr5

141059112

-DIAPH1chr5

140914000

-
intron-3CDSENST00000512390ENST00000253811ARAP3chr5

141059112

-DIAPH1chr5

140914000

-
intron-3CDSENST00000512390ENST00000389054ARAP3chr5

141059112

-DIAPH1chr5

140914000

-
intron-3CDSENST00000512390ENST00000389057ARAP3chr5

141059112

-DIAPH1chr5

140914000

-
intron-3CDSENST00000512390ENST00000398557ARAP3chr5

141059112

-DIAPH1chr5

140914000

-
intron-3CDSENST00000512390ENST00000398562ARAP3chr5

141059112

-DIAPH1chr5

140914000

-
intron-3CDSENST00000512390ENST00000398566ARAP3chr5

141059112

-DIAPH1chr5

140914000

-
intron-3CDSENST00000512390ENST00000518047ARAP3chr5

141059112

-DIAPH1chr5

140914000

-
intron-3CDSENST00000512390ENST00000520569ARAP3chr5

141059112

-DIAPH1chr5

140914000

-
intron-3CDSENST00000513878ENST00000253811ARAP3chr5

141059112

-DIAPH1chr5

140914000

-
intron-3CDSENST00000513878ENST00000389054ARAP3chr5

141059112

-DIAPH1chr5

140914000

-
intron-3CDSENST00000513878ENST00000389057ARAP3chr5

141059112

-DIAPH1chr5

140914000

-
intron-3CDSENST00000513878ENST00000398557ARAP3chr5

141059112

-DIAPH1chr5

140914000

-
intron-3CDSENST00000513878ENST00000398562ARAP3chr5

141059112

-DIAPH1chr5

140914000

-
intron-3CDSENST00000513878ENST00000398566ARAP3chr5

141059112

-DIAPH1chr5

140914000

-
intron-3CDSENST00000513878ENST00000518047ARAP3chr5

141059112

-DIAPH1chr5

140914000

-
intron-3CDSENST00000513878ENST00000520569ARAP3chr5

141059112

-DIAPH1chr5

140914000

-
intron-5UTRENST00000512390ENST00000494967ARAP3chr5

141059112

-DIAPH1chr5

140914000

-
intron-5UTRENST00000513878ENST00000494967ARAP3chr5

141059112

-DIAPH1chr5

140914000

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)
BP loci
(transcript)
Predicted start
(transcript)
Predicted stop
(transcript)
Seq length
(amino acids)
ENST00000239440ARAP3chr5141059112-ENST00000389054DIAPH1chr5140914000-39367646132100495
ENST00000239440ARAP3chr5141059112-ENST00000520569DIAPH1chr5140914000-39307646132100495
ENST00000239440ARAP3chr5141059112-ENST00000253811DIAPH1chr5140914000-39307646132100495
ENST00000239440ARAP3chr5141059112-ENST00000398566DIAPH1chr5140914000-39307646132100495
ENST00000239440ARAP3chr5141059112-ENST00000398562DIAPH1chr5140914000-39307646132100495
ENST00000239440ARAP3chr5141059112-ENST00000398557DIAPH1chr5140914000-39307646132100495
ENST00000239440ARAP3chr5141059112-ENST00000389057DIAPH1chr5140914000-39307646132100495
ENST00000239440ARAP3chr5141059112-ENST00000518047DIAPH1chr5140914000-29777646132100495

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000239440ENST00000389054ARAP3chr5141059112-DIAPH1chr5140914000-0.0022563050.9977437
ENST00000239440ENST00000520569ARAP3chr5141059112-DIAPH1chr5140914000-0.0022512420.9977488
ENST00000239440ENST00000253811ARAP3chr5141059112-DIAPH1chr5140914000-0.0021724430.9978276
ENST00000239440ENST00000398566ARAP3chr5141059112-DIAPH1chr5140914000-0.0021724430.9978276
ENST00000239440ENST00000398562ARAP3chr5141059112-DIAPH1chr5140914000-0.0021724430.9978276
ENST00000239440ENST00000398557ARAP3chr5141059112-DIAPH1chr5140914000-0.0022512420.9977488
ENST00000239440ENST00000389057ARAP3chr5141059112-DIAPH1chr5140914000-0.0022512420.9977488
ENST00000239440ENST00000518047ARAP3chr5141059112-DIAPH1chr5140914000-0.0032214140.99677855

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Fusion Genomic Features for ARAP3-DIAPH1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for ARAP3-DIAPH1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr5:141059112/chr5:140914000)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneARAP3chr5:141059112chr5:140914000ENST00000239440-43381_1392321545.0Compositional biasNote=Pro-rich
HgeneARAP3chr5:141059112chr5:140914000ENST00000239440-4334_682321545.0DomainSAM
TgeneDIAPH1chr5:141059112chr5:140914000ENST0000038905716271039_11968181264.0Coiled coilOntology_term=ECO:0000255
TgeneDIAPH1chr5:141059112chr5:140914000ENST0000039855717281039_11968271273.0Coiled coilOntology_term=ECO:0000255
TgeneDIAPH1chr5:141059112chr5:140914000ENST0000038905716271213_12168181264.0Compositional biasNote=Arg/Lys-rich (basic)
TgeneDIAPH1chr5:141059112chr5:140914000ENST0000039855717281213_12168271273.0Compositional biasNote=Arg/Lys-rich (basic)
TgeneDIAPH1chr5:141059112chr5:140914000ENST0000038905716271194_12228181264.0DomainDAD
TgeneDIAPH1chr5:141059112chr5:140914000ENST0000039855717281194_12228271273.0DomainDAD

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneARAP3chr5:141059112chr5:140914000ENST00000239440-4331462_15422321545.0Compositional biasNote=Pro-rich
HgeneARAP3chr5:141059112chr5:140914000ENST00000239440-4331117_12102321545.0DomainRas-associating
HgeneARAP3chr5:141059112chr5:140914000ENST00000239440-4331223_13252321545.0DomainPH 3
HgeneARAP3chr5:141059112chr5:140914000ENST00000239440-433287_3792321545.0DomainPH 1
HgeneARAP3chr5:141059112chr5:140914000ENST00000239440-433394_4832321545.0DomainPH 2
HgeneARAP3chr5:141059112chr5:140914000ENST00000239440-433480_6112321545.0DomainArf-GAP
HgeneARAP3chr5:141059112chr5:140914000ENST00000239440-433907_10882321545.0DomainRho-GAP
HgeneARAP3chr5:141059112chr5:140914000ENST00000239440-433504_5272321545.0Zinc fingerC4-type
TgeneDIAPH1chr5:141059112chr5:140914000ENST000003890571627468_5728181264.0Coiled coilOntology_term=ECO:0000255
TgeneDIAPH1chr5:141059112chr5:140914000ENST000003985571728468_5728271273.0Coiled coilOntology_term=ECO:0000255
TgeneDIAPH1chr5:141059112chr5:140914000ENST000003890571627583_7648181264.0DomainNote=FH1
TgeneDIAPH1chr5:141059112chr5:140914000ENST000003890571627769_11718181264.0DomainFH2
TgeneDIAPH1chr5:141059112chr5:140914000ENST00000389057162784_4498181264.0DomainGBD/FH3
TgeneDIAPH1chr5:141059112chr5:140914000ENST000003985571728583_7648271273.0DomainNote=FH1
TgeneDIAPH1chr5:141059112chr5:140914000ENST000003985571728769_11718271273.0DomainFH2
TgeneDIAPH1chr5:141059112chr5:140914000ENST00000398557172884_4498271273.0DomainGBD/FH3


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Fusion Gene Sequence for ARAP3-DIAPH1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>5774_5774_1_ARAP3-DIAPH1_ARAP3_chr5_141059112_ENST00000239440_DIAPH1_chr5_140914000_ENST00000253811_length(transcript)=3930nt_BP=764nt
CTCGGACGAGCGGCGGGCACCCGCGAGCGGACGGCGGCCGCGTAGTGAGCAATGGCCTGAGCCCCCATGGCTGCCCCTCAGGACCTGGAC
ATCGCTGTGTGGCTGGCCACGGTGCACCTGGAGCAGTATGCAGACACGTTCCGACGGCATGGCCTGGCTACAGCAGGTGCAGCCCGGGGC
CTGGGCCACGAGGAGTTGAAGCAGTTGGGCATCAGCGCCACAGGGCACCGGAAACGCATTCTACGCCTGCTACAGACAGGCACCGAAGAG
GGCTCCCTGGATCCCAAATCAGATAGTGCCATGGAACCATCCCCCAGCCCAGCCCCGCAAGCCCAGCCCCCTAAGCCCGTGCCGAAGCCC
AGGACCGTGTTTGGTGGACTCAGTGGCCCTGCCACCACTCAGAGACCTGGGCTGAGCCCAGCCCTCGGGGGACCAGGAGTGTCCAGGAGC
CCAGAGCCCAGCCCAAGGCCTCCTCCTCTCCCCACTTCCTCCTCTGAGCAGTCTTCAGCCCTAAATACTGTGGAGATGATGCCTAATTCC
ATCTACTTCGGCCTGGACTCAAGAGGCAGGGCACAGGCAGCTCAGGACAAGGCCCCAGACAGCTCCCAAATCTCTGCCCCCACCCCTGCC
CTCAGGCCCACAACAGGCACAGTGCACATCATGGATCCTGGTTGCCTGTACTATGGTGTCCAACCTGTGGGGACTCCAGGAGCCCCCGAC
AGAAGAGAGAGCAGAGGTGTTTGTCAGGGCAGGGCTGAACACAGCCAAGAAGGATCAAGAAGGTGGAGAAGAAAAGAAATCTGTGCAAAA
GAAAAAAGTAAAAGAGTTAAAGGTGTTGGATTCAAAGACAGCCCAGAATCTCTCAATCTTTTTGGGTTCCTTCCGCATGCCCTATCAAGA
GATTAAGAATGTCATCCTGGAGGTGAATGAGGCTGTTCTGACTGAGTCTATGATCCAGAACCTCATTAAGCAAATGCCAGAGCCAGAGCA
GTTAAAAATGCTTTCTGAACTGAAGGATGAATATGATGACCTGGCTGAGTCAGAGCAGTTTGGCGTGGTGATGGGCACTGTGCCCCGACT
GCGGCCTCGCCTCAATGCCATTCTCTTCAAGCTACAATTCAGCGAGCAAGTGGAGAATATCAAGCCAGAGATTGTGTCTGTCACTGCTGC
ATGTGAGGAGTTACGTAAGAGTGAGAGCTTTTCCAATCTCCTAGAGATTACCTTGCTTGTTGGAAATTACATGAATGCTGGCTCCAGAAA
TGCTGGTGCTTTTGGCTTCAATATCAGCTTCCTCTGTAAGCTTCGAGACACCAAGTCCACAGATCAGAAGATGACGTTGTTACACTTCTT
GGCTGAGTTGTGTGAGAATGACTATCCCGATGTCCTCAAGTTTCCAGACGAGCTTGCCCATGTGGAGAAAGCCAGCCGAGTTTCTGCTGA
AAACTTGCAAAAGAACCTAGATCAGATGAAGAAACAAATTTCTGATGTGGAACGTGATGTTCAGAATTTCCCAGCTGCCACAGATGAAAA
AGACAAGTTTGTTGAAAAAATGACCATCTTTGTGAAGGATGCACAGGAACAGTATAACAAGCTGCGGATGATGCATTCTAACATGGAGAC
CCTCTATAAGGAGCTGGGCGAGTACTTCCTCTTTGACCCCAAGAAGTTGTCTGTTGAAGAATTTTTCATGGATCTTCACAATTTTCGGAA
TATGTTTTTGCAAGCAGTCAAGGAGAACCAGAAGCGGCGGGAGACAGAAGAAAAGATGAGGCGAGCAAAACTAGCCAAGGAGAAGGCAGA
GAAGGAGCGGCTAGAGAAGCAGCAGAAGAGAGAGCAACTCATAGACATGAATGCAGAGGGCGATGAGACAGGTGTGATGGACAGTCTTCT
AGAAGCCCTGCAGTCAGGGGCAGCATTCCGACGGAAGAGAGGGCCCCGTCAAGCCAACAGGAAGGCCGGGTGTGCAGTCACATCTCTGCT
AGCTTCGGAGCTGACCAAGGATGATGCCATGGCTGCTGTTCCTGCCAAGGTGTCCAAGAACAGTGAGACATTCCCCACAATCCTTGAGGA
AGCCAAGGAGTTGGTTGGCCGTGCAAGCTAATGTGGGTCCTGTGACCGCGGCAGCTCCTCAGCGGAGCCGCAGACTGTCCTGCCCTGCAG
CATGTGCCTAAAGGCTCAAGGGGATATTCCTCTGGGGTGGCCACTCCCACCACCCTGACCCTGTCTTTCTCTCTGGCCTGCTGCTCTCTC
AACATCACATACAGCTTCAGCTGCCTGGAGGCCAGAAGGAAAGGGCAGTGCAGGGGAGGCCTGAGCCCGACTTAGCCAGCCCTGGCTGTT
GTATTACCAAAGCAGGGTCCATGTTTGCTGCCTTAACCCTGTCTCCTCTCTGTTACTCAGAGGGCCTCATCTCAGACAAGGCCCAGCCTG
CTTTTTCTCAGCCCTGACTTTCTAATGGGCTTTCCCCCCTAGGTCAGTCTTGCTGGATTTGTGCTTTTCTTTTGTGGTTTCTCTGGCCCT
GAGAATAGCATGGGGCTTGTAAACCTTTGGGCTAGATCCCTCCTTTCATTGCTGTTGTCTCTGCTCTTCCCTCTCCTGGCTGTGGTTATT
TATTATTAGTGGTGTGGCACTGGGAGCTGCTCCTAAGGAAGCAGGGAGCAAATCCCACCTTTACCCCACCTTCCTGGGAAAGGCCTCCAA
AGCAAAGGATCTGGACCAGTTTCCCTGCTGTGCTGTGGCCCAGGCCAGAGCCTGTGGGCAGGCAGGCAGGGCATAGCGACAGTGTGGGAC
CTGCCCCCAGCTTCTGCCACGCTTTATGCCCTTGCCTCTCTGGACGCTCTGCACCAACCCCAGGCTACTGAGCCACCTTCCCTCCTCATG
CCTTCCCTGAGCTTTGGTGCATCTCATCTGGACTATGGGTTGTACTGTGACCATCCCAACACCTCACCCTCTGTCTACAAGGAAATGGGA
GGTGGAGCCTCCTGGCTGAGAAATTGTTTTGCAAATGGATCTATTTTTGTATGAAAAAAAAAATTTTTTTAAAGAAAACTGTTCCTTCCC
CCTTTCCCCTCCATAATGTAAGAAGCTTTGGTGGCAGGTTACAGAGTTCTGGGATTTCTTCTCACAGGCCCAATCCTGAATGTGCCCCTG
GACCTTCTGGACCCTTGAGTCCAAGGCAGATCCTCTCTCCCAGGGAATCCGACACAGGAGGAACCCCTTCTCTGGTTGAGCTGGGCCAGG
CCTAAGAGTAGCAGGAACTCTAAGACCACAGAGTTTTTTATAAATGTATAAATGTATCAAGCCAAATGTGCAGATGCTAACTGGACATTC
TGGGGAACTGGGCACCAGGAGTGCCTTCATACACTGTACCCCAGCTCTCTTCTAAAAGAGAAGTGGGTGGGCACACTGAACTGTTTGGTG
GCCCCAACCACAGGAAGCTGCAATTCTCTGGCTTAGGGTGATACTTTTGCCCTCCTTGTGCCCCTCTCAGCTTTCCATCCCCAGCTAGGA
AGAAAGAATGGCACTCTTGGGCTTGGCCCAGAATTAGAGTTATTAGAGCAAGAGAGAGCTTAGGAAGCATGAGGGCAACTATAGTGAGGC
CTTATTGCCAGGAGGGAGGGTTTTGGTTGCTGGCGCTTGTGTATAAAGGGGCAAGAGCAGCTCCTTTGGACTATTCCTGGGAGGACTCTG
ATGCAGGGCGTCTGTTGCTCCCCTGGGTCACCTCCTCCCTGCTCGCTGACATCTGGGGCTTTGACCCTTTCTTTTTTAATCTACTTTTGC
TAAGATGCATTTAATAAAAAAAAAGAGAGAGAGAGAGAGGTGTGAGGGACAAAATGCAAACCTATTTCCCTTGCCTCATAGGCTTCTGGG

>5774_5774_1_ARAP3-DIAPH1_ARAP3_chr5_141059112_ENST00000239440_DIAPH1_chr5_140914000_ENST00000253811_length(amino acids)=495AA_BP=1
MPPPLPSGPQQAQCTSWILVACTMVSNLWGLQEPPTEERAEVFVRAGLNTAKKDQEGGEEKKSVQKKKVKELKVLDSKTAQNLSIFLGSF
RMPYQEIKNVILEVNEAVLTESMIQNLIKQMPEPEQLKMLSELKDEYDDLAESEQFGVVMGTVPRLRPRLNAILFKLQFSEQVENIKPEI
VSVTAACEELRKSESFSNLLEITLLVGNYMNAGSRNAGAFGFNISFLCKLRDTKSTDQKMTLLHFLAELCENDYPDVLKFPDELAHVEKA
SRVSAENLQKNLDQMKKQISDVERDVQNFPAATDEKDKFVEKMTIFVKDAQEQYNKLRMMHSNMETLYKELGEYFLFDPKKLSVEEFFMD
LHNFRNMFLQAVKENQKRRETEEKMRRAKLAKEKAEKERLEKQQKREQLIDMNAEGDETGVMDSLLEALQSGAAFRRKRGPRQANRKAGC

--------------------------------------------------------------
>5774_5774_2_ARAP3-DIAPH1_ARAP3_chr5_141059112_ENST00000239440_DIAPH1_chr5_140914000_ENST00000389054_length(transcript)=3936nt_BP=764nt
CTCGGACGAGCGGCGGGCACCCGCGAGCGGACGGCGGCCGCGTAGTGAGCAATGGCCTGAGCCCCCATGGCTGCCCCTCAGGACCTGGAC
ATCGCTGTGTGGCTGGCCACGGTGCACCTGGAGCAGTATGCAGACACGTTCCGACGGCATGGCCTGGCTACAGCAGGTGCAGCCCGGGGC
CTGGGCCACGAGGAGTTGAAGCAGTTGGGCATCAGCGCCACAGGGCACCGGAAACGCATTCTACGCCTGCTACAGACAGGCACCGAAGAG
GGCTCCCTGGATCCCAAATCAGATAGTGCCATGGAACCATCCCCCAGCCCAGCCCCGCAAGCCCAGCCCCCTAAGCCCGTGCCGAAGCCC
AGGACCGTGTTTGGTGGACTCAGTGGCCCTGCCACCACTCAGAGACCTGGGCTGAGCCCAGCCCTCGGGGGACCAGGAGTGTCCAGGAGC
CCAGAGCCCAGCCCAAGGCCTCCTCCTCTCCCCACTTCCTCCTCTGAGCAGTCTTCAGCCCTAAATACTGTGGAGATGATGCCTAATTCC
ATCTACTTCGGCCTGGACTCAAGAGGCAGGGCACAGGCAGCTCAGGACAAGGCCCCAGACAGCTCCCAAATCTCTGCCCCCACCCCTGCC
CTCAGGCCCACAACAGGCACAGTGCACATCATGGATCCTGGTTGCCTGTACTATGGTGTCCAACCTGTGGGGACTCCAGGAGCCCCCGAC
AGAAGAGAGAGCAGAGGTGTTTGTCAGGGCAGGGCTGAACACAGCCAAGAAGGATCAAGAAGGTGGAGAAGAAAAGAAATCTGTGCAAAA
GAAAAAAGTAAAAGAGTTAAAGGTGTTGGATTCAAAGACAGCCCAGAATCTCTCAATCTTTTTGGGTTCCTTCCGCATGCCCTATCAAGA
GATTAAGAATGTCATCCTGGAGGTGAATGAGGCTGTTCTGACTGAGTCTATGATCCAGAACCTCATTAAGCAAATGCCAGAGCCAGAGCA
GTTAAAAATGCTTTCTGAACTGAAGGATGAATATGATGACCTGGCTGAGTCAGAGCAGTTTGGCGTGGTGATGGGCACTGTGCCCCGACT
GCGGCCTCGCCTCAATGCCATTCTCTTCAAGCTACAATTCAGCGAGCAAGTGGAGAATATCAAGCCAGAGATTGTGTCTGTCACTGCTGC
ATGTGAGGAGTTACGTAAGAGTGAGAGCTTTTCCAATCTCCTAGAGATTACCTTGCTTGTTGGAAATTACATGAATGCTGGCTCCAGAAA
TGCTGGTGCTTTTGGCTTCAATATCAGCTTCCTCTGTAAGCTTCGAGACACCAAGTCCACAGATCAGAAGATGACGTTGTTACACTTCTT
GGCTGAGTTGTGTGAGAATGACTATCCCGATGTCCTCAAGTTTCCAGACGAGCTTGCCCATGTGGAGAAAGCCAGCCGAGTTTCTGCTGA
AAACTTGCAAAAGAACCTAGATCAGATGAAGAAACAAATTTCTGATGTGGAACGTGATGTTCAGAATTTCCCAGCTGCCACAGATGAAAA
AGACAAGTTTGTTGAAAAAATGACCAGCTTTGTGAAGGATGCACAGGAACAGTATAACAAGCTGCGGATGATGCATTCTAACATGGAGAC
CCTCTATAAGGAGCTGGGCGAGTACTTCCTCTTTGACCCCAAGAAGTTGTCTGTTGAAGAATTTTTCATGGATCTTCACAATTTTCGGAA
TATGTTTTTGCAAGCAGTCAAGGAGAACCAGAAGCGGCGGGAGACAGAAGAAAAGATGAGGCGAGCAAAACTAGCCAAGGAGAAGGCAGA
GAAGGAGCGGCTAGAGAAGCAGCAGAAGAGAGAGCAACTCATAGACATGAATGCAGAGGGCGATGAGACAGGTGTGATGGACAGTCTTCT
AGAAGCCCTGCAGTCAGGGGCAGCATTCCGACGGAAGAGAGGGCCCCGTCAAGCCAACAGGAAGGCCGGGTGTGCAGTCACATCTCTGCT
AGCTTCGGAGCTGACCAAGGATGATGCCATGGCTGCTGTTCCTGCCAAGGTGTCCAAGAACAGTGAGACATTCCCCACAATCCTTGAGGA
AGCCAAGGAGTTGGTTGGCCGTGCAAGCTAATGTGGGTCCTGTGACCGCGGCAGCTCCTCAGCGGAGCCGCAGACTGTCCTGCCCTGCAG
CATGTGCCTAAAGGCTCAAGGGGATATTCCTCTGGGGTGGCCACTCCCACCACCCTGACCCTGTCTTTCTCTCTGGCCTGCTGCTCTCTC
AACATCACATACAGCTTCAGCTGCCTGGAGGCCAGAAGGAAAGGGCAGTGCAGGGGAGGCCTGAGCCCGACTTAGCCAGCCCTGGCTGTT
GTATTACCAAAGCAGGGTCCATGTTTGCTGCCTTAACCCTGTCTCCTCTCTGTTACTCAGAGGGCCTCATCTCAGACAAGGCCCAGCCTG
CTTTTTCTCAGCCCTGACTTTCTAATGGGCTTTCCCCCCTAGGTCAGTCTTGCTGGATTTGTGCTTTTCTTTTGTGGTTTCTCTGGCCCT
GAGAATAGCATGGGGCTTGTAAACCTTTGGGCTAGATCCCTCCTTTCATTGCTGTTGTCTCTGCTCTTCCCTCTCCTGGCTGTGGTTATT
TATTATTAGTGGTGTGGCACTGGGAGCTGCTCCTAAGGAAGCAGGGAGCAAATCCCACCTTTACCCCACCTTCCTGGGAAAGGCCTCCAA
AGCAAAGGATCTGGACCAGTTTCCCTGCTGTGCTGTGGCCCAGGCCAGAGCCTGTGGGCAGGCAGGCAGGGCATAGCGACAGTGTGGGAC
CTGCCCCCAGCTTCTGCCACGCTTTATGCCCTTGCCTCTCTGGACGCTCTGCACCAACCCCAGGCTACTGAGCCACCTTCCCTCCTCATG
CCTTCCCTGAGCTTTGGTGCATCTCATCTGGACTATGGGTTGTACTGTGACCATCCCAACACCTCACCCTCTGTCTACAAGGAAATGGGA
GGTGGAGCCTCCTGGCTGAGAAATTGTTTTGCAAATGGATCTATTTTTGTATGAAAAAAAAAATTTTTTTAAAGAAAACTGTTCCTTCCC
CCTTTCCCCTCCATAATGTAAGAAGCTTTGGTGGCAGGTTACAGAGTTCTGGGATTTCTTCTCACAGGCCCAATCCTGAATGTGCCCCTG
GACCTTCTGGACCCTTGAGTCCAAGGCAGATCCTCTCTCCCAGGGAATCCGACACAGGAGGAACCCCTTCTCTGGTTGAGCTGGGCCAGG
CCTAAGAGTAGCAGGAACTCTAAGACCACAGAGTTTTTTATAAATGTATAAATGTATCAAGCCAAATGTGCAGATGCTAACTGGACATTC
TGGGGAACTGGGCACCAGGAGTGCCTTCATACACTGTACCCCAGCTCTCTTCTAAAAGAGAAGTGGGTGGGCACACTGAACTGTTTGGTG
GCCCCAACCACAGGAAGCTGCAATTCTCTGGCTTAGGGTGATACTTTTGCCCTCCTTGTGCCCCTCTCAGCTTTCCATCCCCAGCTAGGA
AGAAAGAATGGCACTCTTGGGCTTGGCCCAGAATTAGAGTTATTAGAGCAAGAGAGAGCTTAGGAAGCATGAGGGCAACTATAGTGAGGC
CTTATTGCCAGGAGGGAGGGTTTTGGTTGCTGGCGCTTGTGTATAAAGGGGCAAGAGCAGCTCCTTTGGACTATTCCTGGGAGGACTCTG
ATGCAGGGCGTCTGTTGCTCCCCTGGGTCACCTCCTCCCTGCTCGCTGACATCTGGGGCTTTGACCCTTTCTTTTTTAATCTACTTTTGC
TAAGATGCATTTAATAAAAAAAAAGAGAGAGAGAGAGAGGTGTGAGGGACAAAATGCAAACCTATTTCCCTTGCCTCATAGGCTTCTGGG

>5774_5774_2_ARAP3-DIAPH1_ARAP3_chr5_141059112_ENST00000239440_DIAPH1_chr5_140914000_ENST00000389054_length(amino acids)=495AA_BP=1
MPPPLPSGPQQAQCTSWILVACTMVSNLWGLQEPPTEERAEVFVRAGLNTAKKDQEGGEEKKSVQKKKVKELKVLDSKTAQNLSIFLGSF
RMPYQEIKNVILEVNEAVLTESMIQNLIKQMPEPEQLKMLSELKDEYDDLAESEQFGVVMGTVPRLRPRLNAILFKLQFSEQVENIKPEI
VSVTAACEELRKSESFSNLLEITLLVGNYMNAGSRNAGAFGFNISFLCKLRDTKSTDQKMTLLHFLAELCENDYPDVLKFPDELAHVEKA
SRVSAENLQKNLDQMKKQISDVERDVQNFPAATDEKDKFVEKMTSFVKDAQEQYNKLRMMHSNMETLYKELGEYFLFDPKKLSVEEFFMD
LHNFRNMFLQAVKENQKRRETEEKMRRAKLAKEKAEKERLEKQQKREQLIDMNAEGDETGVMDSLLEALQSGAAFRRKRGPRQANRKAGC

--------------------------------------------------------------
>5774_5774_3_ARAP3-DIAPH1_ARAP3_chr5_141059112_ENST00000239440_DIAPH1_chr5_140914000_ENST00000389057_length(transcript)=3930nt_BP=764nt
CTCGGACGAGCGGCGGGCACCCGCGAGCGGACGGCGGCCGCGTAGTGAGCAATGGCCTGAGCCCCCATGGCTGCCCCTCAGGACCTGGAC
ATCGCTGTGTGGCTGGCCACGGTGCACCTGGAGCAGTATGCAGACACGTTCCGACGGCATGGCCTGGCTACAGCAGGTGCAGCCCGGGGC
CTGGGCCACGAGGAGTTGAAGCAGTTGGGCATCAGCGCCACAGGGCACCGGAAACGCATTCTACGCCTGCTACAGACAGGCACCGAAGAG
GGCTCCCTGGATCCCAAATCAGATAGTGCCATGGAACCATCCCCCAGCCCAGCCCCGCAAGCCCAGCCCCCTAAGCCCGTGCCGAAGCCC
AGGACCGTGTTTGGTGGACTCAGTGGCCCTGCCACCACTCAGAGACCTGGGCTGAGCCCAGCCCTCGGGGGACCAGGAGTGTCCAGGAGC
CCAGAGCCCAGCCCAAGGCCTCCTCCTCTCCCCACTTCCTCCTCTGAGCAGTCTTCAGCCCTAAATACTGTGGAGATGATGCCTAATTCC
ATCTACTTCGGCCTGGACTCAAGAGGCAGGGCACAGGCAGCTCAGGACAAGGCCCCAGACAGCTCCCAAATCTCTGCCCCCACCCCTGCC
CTCAGGCCCACAACAGGCACAGTGCACATCATGGATCCTGGTTGCCTGTACTATGGTGTCCAACCTGTGGGGACTCCAGGAGCCCCCGAC
AGAAGAGAGAGCAGAGGTGTTTGTCAGGGCAGGGCTGAACACAGCCAAGAAGGATCAAGAAGGTGGAGAAGAAAAGAAATCTGTGCAAAA
GAAAAAAGTAAAAGAGTTAAAGGTGTTGGATTCAAAGACAGCCCAGAATCTCTCAATCTTTTTGGGTTCCTTCCGCATGCCCTATCAAGA
GATTAAGAATGTCATCCTGGAGGTGAATGAGGCTGTTCTGACTGAGTCTATGATCCAGAACCTCATTAAGCAAATGCCAGAGCCAGAGCA
GTTAAAAATGCTTTCTGAACTGAAGGATGAATATGATGACCTGGCTGAGTCAGAGCAGTTTGGCGTGGTGATGGGCACTGTGCCCCGACT
GCGGCCTCGCCTCAATGCCATTCTCTTCAAGCTACAATTCAGCGAGCAAGTGGAGAATATCAAGCCAGAGATTGTGTCTGTCACTGCTGC
ATGTGAGGAGTTACGTAAGAGTGAGAGCTTTTCCAATCTCCTAGAGATTACCTTGCTTGTTGGAAATTACATGAATGCTGGCTCCAGAAA
TGCTGGTGCTTTTGGCTTCAATATCAGCTTCCTCTGTAAGCTTCGAGACACCAAGTCCACAGATCAGAAGATGACGTTGTTACACTTCTT
GGCTGAGTTGTGTGAGAATGACTATCCCGATGTCCTCAAGTTTCCAGACGAGCTTGCCCATGTGGAGAAAGCCAGCCGAGTTTCTGCTGA
AAACTTGCAAAAGAACCTAGATCAGATGAAGAAACAAATTTCTGATGTGGAACGTGATGTTCAGAATTTCCCAGCTGCCACAGATGAAAA
AGACAAGTTTGTTGAAAAAATGACCAGCTTTGTGAAGGATGCACAGGAACAGTATAACAAGCTGCGGATGATGCATTCTAACATGGAGAC
CCTCTATAAGGAGCTGGGCGAGTACTTCCTCTTTGACCCCAAGAAGTTGTCTGTTGAAGAATTTTTCATGGATCTTCACAATTTTCGGAA
TATGTTTTTGCAAGCAGTCAAGGAGAACCAGAAGCGGCGGGAGACAGAAGAAAAGATGAGGCGAGCAAAACTAGCCAAGGAGAAGGCAGA
GAAGGAGCGGCTAGAGAAGCAGCAGAAGAGAGAGCAACTCATAGACATGAATGCAGAGGGCGATGAGACAGGTGTGATGGACAGTCTTCT
AGAAGCCCTGCAGTCAGGGGCAGCATTCCGACGGAAGAGAGGGCCCCGTCAAGCCAACAGGAAGGCCGGGTGTGCAGTCACATCTCTGCT
AGCTTCGGAGCTGACCAAGGATGATGCCATGGCTGCTGTTCCTGCCAAGGTGTCCAAGAACAGTGAGACATTCCCCACAATCCTTGAGGA
AGCCAAGGAGTTGGTTGGCCGTGCAAGCTAATGTGGGTCCTGTGACCGCGGCAGCTCCTCAGCGGAGCCGCAGACTGTCCTGCCCTGCAG
CATGTGCCTAAAGGCTCAAGGGGATATTCCTCTGGGGTGGCCACTCCCACCACCCTGACCCTGTCTTTCTCTCTGGCCTGCTGCTCTCTC
AACATCACATACAGCTTCAGCTGCCTGGAGGCCAGAAGGAAAGGGCAGTGCAGGGGAGGCCTGAGCCCGACTTAGCCAGCCCTGGCTGTT
GTATTACCAAAGCAGGGTCCATGTTTGCTGCCTTAACCCTGTCTCCTCTCTGTTACTCAGAGGGCCTCATCTCAGACAAGGCCCAGCCTG
CTTTTTCTCAGCCCTGACTTTCTAATGGGCTTTCCCCCCTAGGTCAGTCTTGCTGGATTTGTGCTTTTCTTTTGTGGTTTCTCTGGCCCT
GAGAATAGCATGGGGCTTGTAAACCTTTGGGCTAGATCCCTCCTTTCATTGCTGTTGTCTCTGCTCTTCCCTCTCCTGGCTGTGGTTATT
TATTATTAGTGGTGTGGCACTGGGAGCTGCTCCTAAGGAAGCAGGGAGCAAATCCCACCTTTACCCCACCTTCCTGGGAAAGGCCTCCAA
AGCAAAGGATCTGGACCAGTTTCCCTGCTGTGCTGTGGCCCAGGCCAGAGCCTGTGGGCAGGCAGGCAGGGCATAGCGACAGTGTGGGAC
CTGCCCCCAGCTTCTGCCACGCTTTATGCCCTTGCCTCTCTGGACGCTCTGCACCAACCCCAGGCTACTGAGCCACCTTCCCTCCTCATG
CCTTCCCTGAGCTTTGGTGCATCTCATCTGGACTATGGGTTGTACTGTGACCATCCCAACACCTCACCCTCTGTCTACAAGGAAATGGGA
GGTGGAGCCTCCTGGCTGAGAAATTGTTTTGCAAATGGATCTATTTTTGTATGAAAAAAAAAATTTTTTTAAAGAAAACTGTTCCTTCCC
CCTTTCCCCTCCATAATGTAAGAAGCTTTGGTGGCAGGTTACAGAGTTCTGGGATTTCTTCTCACAGGCCCAATCCTGAATGTGCCCCTG
GACCTTCTGGACCCTTGAGTCCAAGGCAGATCCTCTCTCCCAGGGAATCCGACACAGGAGGAACCCCTTCTCTGGTTGAGCTGGGCCAGG
CCTAAGAGTAGCAGGAACTCTAAGACCACAGAGTTTTTTATAAATGTATAAATGTATCAAGCCAAATGTGCAGATGCTAACTGGACATTC
TGGGGAACTGGGCACCAGGAGTGCCTTCATACACTGTACCCCAGCTCTCTTCTAAAAGAGAAGTGGGTGGGCACACTGAACTGTTTGGTG
GCCCCAACCACAGGAAGCTGCAATTCTCTGGCTTAGGGTGATACTTTTGCCCTCCTTGTGCCCCTCTCAGCTTTCCATCCCCAGCTAGGA
AGAAAGAATGGCACTCTTGGGCTTGGCCCAGAATTAGAGTTATTAGAGCAAGAGAGAGCTTAGGAAGCATGAGGGCAACTATAGTGAGGC
CTTATTGCCAGGAGGGAGGGTTTTGGTTGCTGGCGCTTGTGTATAAAGGGGCAAGAGCAGCTCCTTTGGACTATTCCTGGGAGGACTCTG
ATGCAGGGCGTCTGTTGCTCCCCTGGGTCACCTCCTCCCTGCTCGCTGACATCTGGGGCTTTGACCCTTTCTTTTTTAATCTACTTTTGC
TAAGATGCATTTAATAAAAAAAAAGAGAGAGAGAGAGAGGTGTGAGGGACAAAATGCAAACCTATTTCCCTTGCCTCATAGGCTTCTGGG

>5774_5774_3_ARAP3-DIAPH1_ARAP3_chr5_141059112_ENST00000239440_DIAPH1_chr5_140914000_ENST00000389057_length(amino acids)=495AA_BP=1
MPPPLPSGPQQAQCTSWILVACTMVSNLWGLQEPPTEERAEVFVRAGLNTAKKDQEGGEEKKSVQKKKVKELKVLDSKTAQNLSIFLGSF
RMPYQEIKNVILEVNEAVLTESMIQNLIKQMPEPEQLKMLSELKDEYDDLAESEQFGVVMGTVPRLRPRLNAILFKLQFSEQVENIKPEI
VSVTAACEELRKSESFSNLLEITLLVGNYMNAGSRNAGAFGFNISFLCKLRDTKSTDQKMTLLHFLAELCENDYPDVLKFPDELAHVEKA
SRVSAENLQKNLDQMKKQISDVERDVQNFPAATDEKDKFVEKMTSFVKDAQEQYNKLRMMHSNMETLYKELGEYFLFDPKKLSVEEFFMD
LHNFRNMFLQAVKENQKRRETEEKMRRAKLAKEKAEKERLEKQQKREQLIDMNAEGDETGVMDSLLEALQSGAAFRRKRGPRQANRKAGC

--------------------------------------------------------------
>5774_5774_4_ARAP3-DIAPH1_ARAP3_chr5_141059112_ENST00000239440_DIAPH1_chr5_140914000_ENST00000398557_length(transcript)=3930nt_BP=764nt
CTCGGACGAGCGGCGGGCACCCGCGAGCGGACGGCGGCCGCGTAGTGAGCAATGGCCTGAGCCCCCATGGCTGCCCCTCAGGACCTGGAC
ATCGCTGTGTGGCTGGCCACGGTGCACCTGGAGCAGTATGCAGACACGTTCCGACGGCATGGCCTGGCTACAGCAGGTGCAGCCCGGGGC
CTGGGCCACGAGGAGTTGAAGCAGTTGGGCATCAGCGCCACAGGGCACCGGAAACGCATTCTACGCCTGCTACAGACAGGCACCGAAGAG
GGCTCCCTGGATCCCAAATCAGATAGTGCCATGGAACCATCCCCCAGCCCAGCCCCGCAAGCCCAGCCCCCTAAGCCCGTGCCGAAGCCC
AGGACCGTGTTTGGTGGACTCAGTGGCCCTGCCACCACTCAGAGACCTGGGCTGAGCCCAGCCCTCGGGGGACCAGGAGTGTCCAGGAGC
CCAGAGCCCAGCCCAAGGCCTCCTCCTCTCCCCACTTCCTCCTCTGAGCAGTCTTCAGCCCTAAATACTGTGGAGATGATGCCTAATTCC
ATCTACTTCGGCCTGGACTCAAGAGGCAGGGCACAGGCAGCTCAGGACAAGGCCCCAGACAGCTCCCAAATCTCTGCCCCCACCCCTGCC
CTCAGGCCCACAACAGGCACAGTGCACATCATGGATCCTGGTTGCCTGTACTATGGTGTCCAACCTGTGGGGACTCCAGGAGCCCCCGAC
AGAAGAGAGAGCAGAGGTGTTTGTCAGGGCAGGGCTGAACACAGCCAAGAAGGATCAAGAAGGTGGAGAAGAAAAGAAATCTGTGCAAAA
GAAAAAAGTAAAAGAGTTAAAGGTGTTGGATTCAAAGACAGCCCAGAATCTCTCAATCTTTTTGGGTTCCTTCCGCATGCCCTATCAAGA
GATTAAGAATGTCATCCTGGAGGTGAATGAGGCTGTTCTGACTGAGTCTATGATCCAGAACCTCATTAAGCAAATGCCAGAGCCAGAGCA
GTTAAAAATGCTTTCTGAACTGAAGGATGAATATGATGACCTGGCTGAGTCAGAGCAGTTTGGCGTGGTGATGGGCACTGTGCCCCGACT
GCGGCCTCGCCTCAATGCCATTCTCTTCAAGCTACAATTCAGCGAGCAAGTGGAGAATATCAAGCCAGAGATTGTGTCTGTCACTGCTGC
ATGTGAGGAGTTACGTAAGAGTGAGAGCTTTTCCAATCTCCTAGAGATTACCTTGCTTGTTGGAAATTACATGAATGCTGGCTCCAGAAA
TGCTGGTGCTTTTGGCTTCAATATCAGCTTCCTCTGTAAGCTTCGAGACACCAAGTCCACAGATCAGAAGATGACGTTGTTACACTTCTT
GGCTGAGTTGTGTGAGAATGACTATCCCGATGTCCTCAAGTTTCCAGACGAGCTTGCCCATGTGGAGAAAGCCAGCCGAGTTTCTGCTGA
AAACTTGCAAAAGAACCTAGATCAGATGAAGAAACAAATTTCTGATGTGGAACGTGATGTTCAGAATTTCCCAGCTGCCACAGATGAAAA
AGACAAGTTTGTTGAAAAAATGACCAGCTTTGTGAAGGATGCACAGGAACAGTATAACAAGCTGCGGATGATGCATTCTAACATGGAGAC
CCTCTATAAGGAGCTGGGCGAGTACTTCCTCTTTGACCCCAAGAAGTTGTCTGTTGAAGAATTTTTCATGGATCTTCACAATTTTCGGAA
TATGTTTTTGCAAGCAGTCAAGGAGAACCAGAAGCGGCGGGAGACAGAAGAAAAGATGAGGCGAGCAAAACTAGCCAAGGAGAAGGCAGA
GAAGGAGCGGCTAGAGAAGCAGCAGAAGAGAGAGCAACTCATAGACATGAATGCAGAGGGCGATGAGACAGGTGTGATGGACAGTCTTCT
AGAAGCCCTGCAGTCAGGGGCAGCATTCCGACGGAAGAGAGGGCCCCGTCAAGCCAACAGGAAGGCCGGGTGTGCAGTCACATCTCTGCT
AGCTTCGGAGCTGACCAAGGATGATGCCATGGCTGCTGTTCCTGCCAAGGTGTCCAAGAACAGTGAGACATTCCCCACAATCCTTGAGGA
AGCCAAGGAGTTGGTTGGCCGTGCAAGCTAATGTGGGTCCTGTGACCGCGGCAGCTCCTCAGCGGAGCCGCAGACTGTCCTGCCCTGCAG
CATGTGCCTAAAGGCTCAAGGGGATATTCCTCTGGGGTGGCCACTCCCACCACCCTGACCCTGTCTTTCTCTCTGGCCTGCTGCTCTCTC
AACATCACATACAGCTTCAGCTGCCTGGAGGCCAGAAGGAAAGGGCAGTGCAGGGGAGGCCTGAGCCCGACTTAGCCAGCCCTGGCTGTT
GTATTACCAAAGCAGGGTCCATGTTTGCTGCCTTAACCCTGTCTCCTCTCTGTTACTCAGAGGGCCTCATCTCAGACAAGGCCCAGCCTG
CTTTTTCTCAGCCCTGACTTTCTAATGGGCTTTCCCCCCTAGGTCAGTCTTGCTGGATTTGTGCTTTTCTTTTGTGGTTTCTCTGGCCCT
GAGAATAGCATGGGGCTTGTAAACCTTTGGGCTAGATCCCTCCTTTCATTGCTGTTGTCTCTGCTCTTCCCTCTCCTGGCTGTGGTTATT
TATTATTAGTGGTGTGGCACTGGGAGCTGCTCCTAAGGAAGCAGGGAGCAAATCCCACCTTTACCCCACCTTCCTGGGAAAGGCCTCCAA
AGCAAAGGATCTGGACCAGTTTCCCTGCTGTGCTGTGGCCCAGGCCAGAGCCTGTGGGCAGGCAGGCAGGGCATAGCGACAGTGTGGGAC
CTGCCCCCAGCTTCTGCCACGCTTTATGCCCTTGCCTCTCTGGACGCTCTGCACCAACCCCAGGCTACTGAGCCACCTTCCCTCCTCATG
CCTTCCCTGAGCTTTGGTGCATCTCATCTGGACTATGGGTTGTACTGTGACCATCCCAACACCTCACCCTCTGTCTACAAGGAAATGGGA
GGTGGAGCCTCCTGGCTGAGAAATTGTTTTGCAAATGGATCTATTTTTGTATGAAAAAAAAAATTTTTTTAAAGAAAACTGTTCCTTCCC
CCTTTCCCCTCCATAATGTAAGAAGCTTTGGTGGCAGGTTACAGAGTTCTGGGATTTCTTCTCACAGGCCCAATCCTGAATGTGCCCCTG
GACCTTCTGGACCCTTGAGTCCAAGGCAGATCCTCTCTCCCAGGGAATCCGACACAGGAGGAACCCCTTCTCTGGTTGAGCTGGGCCAGG
CCTAAGAGTAGCAGGAACTCTAAGACCACAGAGTTTTTTATAAATGTATAAATGTATCAAGCCAAATGTGCAGATGCTAACTGGACATTC
TGGGGAACTGGGCACCAGGAGTGCCTTCATACACTGTACCCCAGCTCTCTTCTAAAAGAGAAGTGGGTGGGCACACTGAACTGTTTGGTG
GCCCCAACCACAGGAAGCTGCAATTCTCTGGCTTAGGGTGATACTTTTGCCCTCCTTGTGCCCCTCTCAGCTTTCCATCCCCAGCTAGGA
AGAAAGAATGGCACTCTTGGGCTTGGCCCAGAATTAGAGTTATTAGAGCAAGAGAGAGCTTAGGAAGCATGAGGGCAACTATAGTGAGGC
CTTATTGCCAGGAGGGAGGGTTTTGGTTGCTGGCGCTTGTGTATAAAGGGGCAAGAGCAGCTCCTTTGGACTATTCCTGGGAGGACTCTG
ATGCAGGGCGTCTGTTGCTCCCCTGGGTCACCTCCTCCCTGCTCGCTGACATCTGGGGCTTTGACCCTTTCTTTTTTAATCTACTTTTGC
TAAGATGCATTTAATAAAAAAAAAGAGAGAGAGAGAGAGGTGTGAGGGACAAAATGCAAACCTATTTCCCTTGCCTCATAGGCTTCTGGG

>5774_5774_4_ARAP3-DIAPH1_ARAP3_chr5_141059112_ENST00000239440_DIAPH1_chr5_140914000_ENST00000398557_length(amino acids)=495AA_BP=1
MPPPLPSGPQQAQCTSWILVACTMVSNLWGLQEPPTEERAEVFVRAGLNTAKKDQEGGEEKKSVQKKKVKELKVLDSKTAQNLSIFLGSF
RMPYQEIKNVILEVNEAVLTESMIQNLIKQMPEPEQLKMLSELKDEYDDLAESEQFGVVMGTVPRLRPRLNAILFKLQFSEQVENIKPEI
VSVTAACEELRKSESFSNLLEITLLVGNYMNAGSRNAGAFGFNISFLCKLRDTKSTDQKMTLLHFLAELCENDYPDVLKFPDELAHVEKA
SRVSAENLQKNLDQMKKQISDVERDVQNFPAATDEKDKFVEKMTSFVKDAQEQYNKLRMMHSNMETLYKELGEYFLFDPKKLSVEEFFMD
LHNFRNMFLQAVKENQKRRETEEKMRRAKLAKEKAEKERLEKQQKREQLIDMNAEGDETGVMDSLLEALQSGAAFRRKRGPRQANRKAGC

--------------------------------------------------------------
>5774_5774_5_ARAP3-DIAPH1_ARAP3_chr5_141059112_ENST00000239440_DIAPH1_chr5_140914000_ENST00000398562_length(transcript)=3930nt_BP=764nt
CTCGGACGAGCGGCGGGCACCCGCGAGCGGACGGCGGCCGCGTAGTGAGCAATGGCCTGAGCCCCCATGGCTGCCCCTCAGGACCTGGAC
ATCGCTGTGTGGCTGGCCACGGTGCACCTGGAGCAGTATGCAGACACGTTCCGACGGCATGGCCTGGCTACAGCAGGTGCAGCCCGGGGC
CTGGGCCACGAGGAGTTGAAGCAGTTGGGCATCAGCGCCACAGGGCACCGGAAACGCATTCTACGCCTGCTACAGACAGGCACCGAAGAG
GGCTCCCTGGATCCCAAATCAGATAGTGCCATGGAACCATCCCCCAGCCCAGCCCCGCAAGCCCAGCCCCCTAAGCCCGTGCCGAAGCCC
AGGACCGTGTTTGGTGGACTCAGTGGCCCTGCCACCACTCAGAGACCTGGGCTGAGCCCAGCCCTCGGGGGACCAGGAGTGTCCAGGAGC
CCAGAGCCCAGCCCAAGGCCTCCTCCTCTCCCCACTTCCTCCTCTGAGCAGTCTTCAGCCCTAAATACTGTGGAGATGATGCCTAATTCC
ATCTACTTCGGCCTGGACTCAAGAGGCAGGGCACAGGCAGCTCAGGACAAGGCCCCAGACAGCTCCCAAATCTCTGCCCCCACCCCTGCC
CTCAGGCCCACAACAGGCACAGTGCACATCATGGATCCTGGTTGCCTGTACTATGGTGTCCAACCTGTGGGGACTCCAGGAGCCCCCGAC
AGAAGAGAGAGCAGAGGTGTTTGTCAGGGCAGGGCTGAACACAGCCAAGAAGGATCAAGAAGGTGGAGAAGAAAAGAAATCTGTGCAAAA
GAAAAAAGTAAAAGAGTTAAAGGTGTTGGATTCAAAGACAGCCCAGAATCTCTCAATCTTTTTGGGTTCCTTCCGCATGCCCTATCAAGA
GATTAAGAATGTCATCCTGGAGGTGAATGAGGCTGTTCTGACTGAGTCTATGATCCAGAACCTCATTAAGCAAATGCCAGAGCCAGAGCA
GTTAAAAATGCTTTCTGAACTGAAGGATGAATATGATGACCTGGCTGAGTCAGAGCAGTTTGGCGTGGTGATGGGCACTGTGCCCCGACT
GCGGCCTCGCCTCAATGCCATTCTCTTCAAGCTACAATTCAGCGAGCAAGTGGAGAATATCAAGCCAGAGATTGTGTCTGTCACTGCTGC
ATGTGAGGAGTTACGTAAGAGTGAGAGCTTTTCCAATCTCCTAGAGATTACCTTGCTTGTTGGAAATTACATGAATGCTGGCTCCAGAAA
TGCTGGTGCTTTTGGCTTCAATATCAGCTTCCTCTGTAAGCTTCGAGACACCAAGTCCACAGATCAGAAGATGACGTTGTTACACTTCTT
GGCTGAGTTGTGTGAGAATGACTATCCCGATGTCCTCAAGTTTCCAGACGAGCTTGCCCATGTGGAGAAAGCCAGCCGAGTTTCTGCTGA
AAACTTGCAAAAGAACCTAGATCAGATGAAGAAACAAATTTCTGATGTGGAACGTGATGTTCAGAATTTCCCAGCTGCCACAGATGAAAA
AGACAAGTTTGTTGAAAAAATGACCATCTTTGTGAAGGATGCACAGGAACAGTATAACAAGCTGCGGATGATGCATTCTAACATGGAGAC
CCTCTATAAGGAGCTGGGCGAGTACTTCCTCTTTGACCCCAAGAAGTTGTCTGTTGAAGAATTTTTCATGGATCTTCACAATTTTCGGAA
TATGTTTTTGCAAGCAGTCAAGGAGAACCAGAAGCGGCGGGAGACAGAAGAAAAGATGAGGCGAGCAAAACTAGCCAAGGAGAAGGCAGA
GAAGGAGCGGCTAGAGAAGCAGCAGAAGAGAGAGCAACTCATAGACATGAATGCAGAGGGCGATGAGACAGGTGTGATGGACAGTCTTCT
AGAAGCCCTGCAGTCAGGGGCAGCATTCCGACGGAAGAGAGGGCCCCGTCAAGCCAACAGGAAGGCCGGGTGTGCAGTCACATCTCTGCT
AGCTTCGGAGCTGACCAAGGATGATGCCATGGCTGCTGTTCCTGCCAAGGTGTCCAAGAACAGTGAGACATTCCCCACAATCCTTGAGGA
AGCCAAGGAGTTGGTTGGCCGTGCAAGCTAATGTGGGTCCTGTGACCGCGGCAGCTCCTCAGCGGAGCCGCAGACTGTCCTGCCCTGCAG
CATGTGCCTAAAGGCTCAAGGGGATATTCCTCTGGGGTGGCCACTCCCACCACCCTGACCCTGTCTTTCTCTCTGGCCTGCTGCTCTCTC
AACATCACATACAGCTTCAGCTGCCTGGAGGCCAGAAGGAAAGGGCAGTGCAGGGGAGGCCTGAGCCCGACTTAGCCAGCCCTGGCTGTT
GTATTACCAAAGCAGGGTCCATGTTTGCTGCCTTAACCCTGTCTCCTCTCTGTTACTCAGAGGGCCTCATCTCAGACAAGGCCCAGCCTG
CTTTTTCTCAGCCCTGACTTTCTAATGGGCTTTCCCCCCTAGGTCAGTCTTGCTGGATTTGTGCTTTTCTTTTGTGGTTTCTCTGGCCCT
GAGAATAGCATGGGGCTTGTAAACCTTTGGGCTAGATCCCTCCTTTCATTGCTGTTGTCTCTGCTCTTCCCTCTCCTGGCTGTGGTTATT
TATTATTAGTGGTGTGGCACTGGGAGCTGCTCCTAAGGAAGCAGGGAGCAAATCCCACCTTTACCCCACCTTCCTGGGAAAGGCCTCCAA
AGCAAAGGATCTGGACCAGTTTCCCTGCTGTGCTGTGGCCCAGGCCAGAGCCTGTGGGCAGGCAGGCAGGGCATAGCGACAGTGTGGGAC
CTGCCCCCAGCTTCTGCCACGCTTTATGCCCTTGCCTCTCTGGACGCTCTGCACCAACCCCAGGCTACTGAGCCACCTTCCCTCCTCATG
CCTTCCCTGAGCTTTGGTGCATCTCATCTGGACTATGGGTTGTACTGTGACCATCCCAACACCTCACCCTCTGTCTACAAGGAAATGGGA
GGTGGAGCCTCCTGGCTGAGAAATTGTTTTGCAAATGGATCTATTTTTGTATGAAAAAAAAAATTTTTTTAAAGAAAACTGTTCCTTCCC
CCTTTCCCCTCCATAATGTAAGAAGCTTTGGTGGCAGGTTACAGAGTTCTGGGATTTCTTCTCACAGGCCCAATCCTGAATGTGCCCCTG
GACCTTCTGGACCCTTGAGTCCAAGGCAGATCCTCTCTCCCAGGGAATCCGACACAGGAGGAACCCCTTCTCTGGTTGAGCTGGGCCAGG
CCTAAGAGTAGCAGGAACTCTAAGACCACAGAGTTTTTTATAAATGTATAAATGTATCAAGCCAAATGTGCAGATGCTAACTGGACATTC
TGGGGAACTGGGCACCAGGAGTGCCTTCATACACTGTACCCCAGCTCTCTTCTAAAAGAGAAGTGGGTGGGCACACTGAACTGTTTGGTG
GCCCCAACCACAGGAAGCTGCAATTCTCTGGCTTAGGGTGATACTTTTGCCCTCCTTGTGCCCCTCTCAGCTTTCCATCCCCAGCTAGGA
AGAAAGAATGGCACTCTTGGGCTTGGCCCAGAATTAGAGTTATTAGAGCAAGAGAGAGCTTAGGAAGCATGAGGGCAACTATAGTGAGGC
CTTATTGCCAGGAGGGAGGGTTTTGGTTGCTGGCGCTTGTGTATAAAGGGGCAAGAGCAGCTCCTTTGGACTATTCCTGGGAGGACTCTG
ATGCAGGGCGTCTGTTGCTCCCCTGGGTCACCTCCTCCCTGCTCGCTGACATCTGGGGCTTTGACCCTTTCTTTTTTAATCTACTTTTGC
TAAGATGCATTTAATAAAAAAAAAGAGAGAGAGAGAGAGGTGTGAGGGACAAAATGCAAACCTATTTCCCTTGCCTCATAGGCTTCTGGG

>5774_5774_5_ARAP3-DIAPH1_ARAP3_chr5_141059112_ENST00000239440_DIAPH1_chr5_140914000_ENST00000398562_length(amino acids)=495AA_BP=1
MPPPLPSGPQQAQCTSWILVACTMVSNLWGLQEPPTEERAEVFVRAGLNTAKKDQEGGEEKKSVQKKKVKELKVLDSKTAQNLSIFLGSF
RMPYQEIKNVILEVNEAVLTESMIQNLIKQMPEPEQLKMLSELKDEYDDLAESEQFGVVMGTVPRLRPRLNAILFKLQFSEQVENIKPEI
VSVTAACEELRKSESFSNLLEITLLVGNYMNAGSRNAGAFGFNISFLCKLRDTKSTDQKMTLLHFLAELCENDYPDVLKFPDELAHVEKA
SRVSAENLQKNLDQMKKQISDVERDVQNFPAATDEKDKFVEKMTIFVKDAQEQYNKLRMMHSNMETLYKELGEYFLFDPKKLSVEEFFMD
LHNFRNMFLQAVKENQKRRETEEKMRRAKLAKEKAEKERLEKQQKREQLIDMNAEGDETGVMDSLLEALQSGAAFRRKRGPRQANRKAGC

--------------------------------------------------------------
>5774_5774_6_ARAP3-DIAPH1_ARAP3_chr5_141059112_ENST00000239440_DIAPH1_chr5_140914000_ENST00000398566_length(transcript)=3930nt_BP=764nt
CTCGGACGAGCGGCGGGCACCCGCGAGCGGACGGCGGCCGCGTAGTGAGCAATGGCCTGAGCCCCCATGGCTGCCCCTCAGGACCTGGAC
ATCGCTGTGTGGCTGGCCACGGTGCACCTGGAGCAGTATGCAGACACGTTCCGACGGCATGGCCTGGCTACAGCAGGTGCAGCCCGGGGC
CTGGGCCACGAGGAGTTGAAGCAGTTGGGCATCAGCGCCACAGGGCACCGGAAACGCATTCTACGCCTGCTACAGACAGGCACCGAAGAG
GGCTCCCTGGATCCCAAATCAGATAGTGCCATGGAACCATCCCCCAGCCCAGCCCCGCAAGCCCAGCCCCCTAAGCCCGTGCCGAAGCCC
AGGACCGTGTTTGGTGGACTCAGTGGCCCTGCCACCACTCAGAGACCTGGGCTGAGCCCAGCCCTCGGGGGACCAGGAGTGTCCAGGAGC
CCAGAGCCCAGCCCAAGGCCTCCTCCTCTCCCCACTTCCTCCTCTGAGCAGTCTTCAGCCCTAAATACTGTGGAGATGATGCCTAATTCC
ATCTACTTCGGCCTGGACTCAAGAGGCAGGGCACAGGCAGCTCAGGACAAGGCCCCAGACAGCTCCCAAATCTCTGCCCCCACCCCTGCC
CTCAGGCCCACAACAGGCACAGTGCACATCATGGATCCTGGTTGCCTGTACTATGGTGTCCAACCTGTGGGGACTCCAGGAGCCCCCGAC
AGAAGAGAGAGCAGAGGTGTTTGTCAGGGCAGGGCTGAACACAGCCAAGAAGGATCAAGAAGGTGGAGAAGAAAAGAAATCTGTGCAAAA
GAAAAAAGTAAAAGAGTTAAAGGTGTTGGATTCAAAGACAGCCCAGAATCTCTCAATCTTTTTGGGTTCCTTCCGCATGCCCTATCAAGA
GATTAAGAATGTCATCCTGGAGGTGAATGAGGCTGTTCTGACTGAGTCTATGATCCAGAACCTCATTAAGCAAATGCCAGAGCCAGAGCA
GTTAAAAATGCTTTCTGAACTGAAGGATGAATATGATGACCTGGCTGAGTCAGAGCAGTTTGGCGTGGTGATGGGCACTGTGCCCCGACT
GCGGCCTCGCCTCAATGCCATTCTCTTCAAGCTACAATTCAGCGAGCAAGTGGAGAATATCAAGCCAGAGATTGTGTCTGTCACTGCTGC
ATGTGAGGAGTTACGTAAGAGTGAGAGCTTTTCCAATCTCCTAGAGATTACCTTGCTTGTTGGAAATTACATGAATGCTGGCTCCAGAAA
TGCTGGTGCTTTTGGCTTCAATATCAGCTTCCTCTGTAAGCTTCGAGACACCAAGTCCACAGATCAGAAGATGACGTTGTTACACTTCTT
GGCTGAGTTGTGTGAGAATGACTATCCCGATGTCCTCAAGTTTCCAGACGAGCTTGCCCATGTGGAGAAAGCCAGCCGAGTTTCTGCTGA
AAACTTGCAAAAGAACCTAGATCAGATGAAGAAACAAATTTCTGATGTGGAACGTGATGTTCAGAATTTCCCAGCTGCCACAGATGAAAA
AGACAAGTTTGTTGAAAAAATGACCATCTTTGTGAAGGATGCACAGGAACAGTATAACAAGCTGCGGATGATGCATTCTAACATGGAGAC
CCTCTATAAGGAGCTGGGCGAGTACTTCCTCTTTGACCCCAAGAAGTTGTCTGTTGAAGAATTTTTCATGGATCTTCACAATTTTCGGAA
TATGTTTTTGCAAGCAGTCAAGGAGAACCAGAAGCGGCGGGAGACAGAAGAAAAGATGAGGCGAGCAAAACTAGCCAAGGAGAAGGCAGA
GAAGGAGCGGCTAGAGAAGCAGCAGAAGAGAGAGCAACTCATAGACATGAATGCAGAGGGCGATGAGACAGGTGTGATGGACAGTCTTCT
AGAAGCCCTGCAGTCAGGGGCAGCATTCCGACGGAAGAGAGGGCCCCGTCAAGCCAACAGGAAGGCCGGGTGTGCAGTCACATCTCTGCT
AGCTTCGGAGCTGACCAAGGATGATGCCATGGCTGCTGTTCCTGCCAAGGTGTCCAAGAACAGTGAGACATTCCCCACAATCCTTGAGGA
AGCCAAGGAGTTGGTTGGCCGTGCAAGCTAATGTGGGTCCTGTGACCGCGGCAGCTCCTCAGCGGAGCCGCAGACTGTCCTGCCCTGCAG
CATGTGCCTAAAGGCTCAAGGGGATATTCCTCTGGGGTGGCCACTCCCACCACCCTGACCCTGTCTTTCTCTCTGGCCTGCTGCTCTCTC
AACATCACATACAGCTTCAGCTGCCTGGAGGCCAGAAGGAAAGGGCAGTGCAGGGGAGGCCTGAGCCCGACTTAGCCAGCCCTGGCTGTT
GTATTACCAAAGCAGGGTCCATGTTTGCTGCCTTAACCCTGTCTCCTCTCTGTTACTCAGAGGGCCTCATCTCAGACAAGGCCCAGCCTG
CTTTTTCTCAGCCCTGACTTTCTAATGGGCTTTCCCCCCTAGGTCAGTCTTGCTGGATTTGTGCTTTTCTTTTGTGGTTTCTCTGGCCCT
GAGAATAGCATGGGGCTTGTAAACCTTTGGGCTAGATCCCTCCTTTCATTGCTGTTGTCTCTGCTCTTCCCTCTCCTGGCTGTGGTTATT
TATTATTAGTGGTGTGGCACTGGGAGCTGCTCCTAAGGAAGCAGGGAGCAAATCCCACCTTTACCCCACCTTCCTGGGAAAGGCCTCCAA
AGCAAAGGATCTGGACCAGTTTCCCTGCTGTGCTGTGGCCCAGGCCAGAGCCTGTGGGCAGGCAGGCAGGGCATAGCGACAGTGTGGGAC
CTGCCCCCAGCTTCTGCCACGCTTTATGCCCTTGCCTCTCTGGACGCTCTGCACCAACCCCAGGCTACTGAGCCACCTTCCCTCCTCATG
CCTTCCCTGAGCTTTGGTGCATCTCATCTGGACTATGGGTTGTACTGTGACCATCCCAACACCTCACCCTCTGTCTACAAGGAAATGGGA
GGTGGAGCCTCCTGGCTGAGAAATTGTTTTGCAAATGGATCTATTTTTGTATGAAAAAAAAAATTTTTTTAAAGAAAACTGTTCCTTCCC
CCTTTCCCCTCCATAATGTAAGAAGCTTTGGTGGCAGGTTACAGAGTTCTGGGATTTCTTCTCACAGGCCCAATCCTGAATGTGCCCCTG
GACCTTCTGGACCCTTGAGTCCAAGGCAGATCCTCTCTCCCAGGGAATCCGACACAGGAGGAACCCCTTCTCTGGTTGAGCTGGGCCAGG
CCTAAGAGTAGCAGGAACTCTAAGACCACAGAGTTTTTTATAAATGTATAAATGTATCAAGCCAAATGTGCAGATGCTAACTGGACATTC
TGGGGAACTGGGCACCAGGAGTGCCTTCATACACTGTACCCCAGCTCTCTTCTAAAAGAGAAGTGGGTGGGCACACTGAACTGTTTGGTG
GCCCCAACCACAGGAAGCTGCAATTCTCTGGCTTAGGGTGATACTTTTGCCCTCCTTGTGCCCCTCTCAGCTTTCCATCCCCAGCTAGGA
AGAAAGAATGGCACTCTTGGGCTTGGCCCAGAATTAGAGTTATTAGAGCAAGAGAGAGCTTAGGAAGCATGAGGGCAACTATAGTGAGGC
CTTATTGCCAGGAGGGAGGGTTTTGGTTGCTGGCGCTTGTGTATAAAGGGGCAAGAGCAGCTCCTTTGGACTATTCCTGGGAGGACTCTG
ATGCAGGGCGTCTGTTGCTCCCCTGGGTCACCTCCTCCCTGCTCGCTGACATCTGGGGCTTTGACCCTTTCTTTTTTAATCTACTTTTGC
TAAGATGCATTTAATAAAAAAAAAGAGAGAGAGAGAGAGGTGTGAGGGACAAAATGCAAACCTATTTCCCTTGCCTCATAGGCTTCTGGG

>5774_5774_6_ARAP3-DIAPH1_ARAP3_chr5_141059112_ENST00000239440_DIAPH1_chr5_140914000_ENST00000398566_length(amino acids)=495AA_BP=1
MPPPLPSGPQQAQCTSWILVACTMVSNLWGLQEPPTEERAEVFVRAGLNTAKKDQEGGEEKKSVQKKKVKELKVLDSKTAQNLSIFLGSF
RMPYQEIKNVILEVNEAVLTESMIQNLIKQMPEPEQLKMLSELKDEYDDLAESEQFGVVMGTVPRLRPRLNAILFKLQFSEQVENIKPEI
VSVTAACEELRKSESFSNLLEITLLVGNYMNAGSRNAGAFGFNISFLCKLRDTKSTDQKMTLLHFLAELCENDYPDVLKFPDELAHVEKA
SRVSAENLQKNLDQMKKQISDVERDVQNFPAATDEKDKFVEKMTIFVKDAQEQYNKLRMMHSNMETLYKELGEYFLFDPKKLSVEEFFMD
LHNFRNMFLQAVKENQKRRETEEKMRRAKLAKEKAEKERLEKQQKREQLIDMNAEGDETGVMDSLLEALQSGAAFRRKRGPRQANRKAGC

--------------------------------------------------------------
>5774_5774_7_ARAP3-DIAPH1_ARAP3_chr5_141059112_ENST00000239440_DIAPH1_chr5_140914000_ENST00000518047_length(transcript)=2977nt_BP=764nt
CTCGGACGAGCGGCGGGCACCCGCGAGCGGACGGCGGCCGCGTAGTGAGCAATGGCCTGAGCCCCCATGGCTGCCCCTCAGGACCTGGAC
ATCGCTGTGTGGCTGGCCACGGTGCACCTGGAGCAGTATGCAGACACGTTCCGACGGCATGGCCTGGCTACAGCAGGTGCAGCCCGGGGC
CTGGGCCACGAGGAGTTGAAGCAGTTGGGCATCAGCGCCACAGGGCACCGGAAACGCATTCTACGCCTGCTACAGACAGGCACCGAAGAG
GGCTCCCTGGATCCCAAATCAGATAGTGCCATGGAACCATCCCCCAGCCCAGCCCCGCAAGCCCAGCCCCCTAAGCCCGTGCCGAAGCCC
AGGACCGTGTTTGGTGGACTCAGTGGCCCTGCCACCACTCAGAGACCTGGGCTGAGCCCAGCCCTCGGGGGACCAGGAGTGTCCAGGAGC
CCAGAGCCCAGCCCAAGGCCTCCTCCTCTCCCCACTTCCTCCTCTGAGCAGTCTTCAGCCCTAAATACTGTGGAGATGATGCCTAATTCC
ATCTACTTCGGCCTGGACTCAAGAGGCAGGGCACAGGCAGCTCAGGACAAGGCCCCAGACAGCTCCCAAATCTCTGCCCCCACCCCTGCC
CTCAGGCCCACAACAGGCACAGTGCACATCATGGATCCTGGTTGCCTGTACTATGGTGTCCAACCTGTGGGGACTCCAGGAGCCCCCGAC
AGAAGAGAGAGCAGAGGTGTTTGTCAGGGCAGGGCTGAACACAGCCAAGAAGGATCAAGAAGGTGGAGAAGAAAAGAAATCTGTGCAAAA
GAAAAAAGTAAAAGAGTTAAAGGTGTTGGATTCAAAGACAGCCCAGAATCTCTCAATCTTTTTGGGTTCCTTCCGCATGCCCTATCAAGA
GATTAAGAATGTCATCCTGGAGGTGAATGAGGCTGTTCTGACTGAGTCTATGATCCAGAACCTCATTAAGCAAATGCCAGAGCCAGAGCA
GTTAAAAATGCTTTCTGAACTGAAGGATGAATATGATGACCTGGCTGAGTCAGAGCAGTTTGGCGTGGTGATGGGCACTGTGCCCCGACT
GCGGCCTCGCCTCAATGCCATTCTCTTCAAGCTACAATTCAGCGAGCAAGTGGAGAATATCAAGCCAGAGATTGTGTCTGTCACTGCTGC
ATGTGAGGAGTTACGTAAGAGTGAGAGCTTTTCCAATCTCCTAGAGATTACCTTGCTTGTTGGAAATTACATGAATGCTGGCTCCAGAAA
TGCTGGTGCTTTTGGCTTCAATATCAGCTTCCTCTGTAAGCTTCGAGACACCAAGTCCACAGATCAGAAGATGACGTTGTTACACTTCTT
GGCTGAGTTGTGTGAGAATGACTATCCCGATGTCCTCAAGTTTCCAGACGAGCTTGCCCATGTGGAGAAAGCCAGCCGAGTTTCTGCTGA
AAACTTGCAAAAGAACCTAGATCAGATGAAGAAACAAATTTCTGATGTGGAACGTGATGTTCAGAATTTCCCAGCTGCCACAGATGAAAA
AGACAAGTTTGTTGAAAAAATGACCAGCTTTGTGAAGGATGCACAGGAACAGTATAACAAGCTGCGGATGATGCATTCTAACATGGAGAC
CCTCTATAAGGAGCTGGGCGAGTACTTCCTCTTTGACCCCAAGAAGTTGTCTGTTGAAGAATTTTTCATGGATCTTCACAATTTTCGGAA
TATGTTTTTGCAAGCAGTCAAGGAGAACCAGAAGCGGCGGGAGACAGAAGAAAAGATGAGGCGAGCAAAACTAGCCAAGGAGAAGGCAGA
GAAGGAGCGGCTAGAGAAGCAGCAGAAGAGAGAGCAACTCATAGACATGAATGCAGAGGGCGATGAGACAGGTGTGATGGACAGTCTTCT
AGAAGCCCTGCAGTCAGGGGCAGCATTCCGACGGAAGAGAGGGCCCCGTCAAGCCAACAGGAAGGCCGGGTGTGCAGTCACATCTCTGCT
AGCTTCGGAGCTGACCAAGGATGATGCCATGGCTGCTGTTCCTGCCAAGGTGTCCAAGAACAGTGAGACATTCCCCACAATCCTTGAGGA
AGCCAAGGAGTTGGTTGGCCGTGCAAGCTAATGTGGGTCCTGTGACCGCGGCAGCTCCTCAGCGGAGCCGCAGACTGTCCTGCCCTGCAG
CATGTGCCTAAAGGCTCAAGGGGATATTCCTCTGGGGTGGCCACTCCCACCACCCTGACCCTGTCTTTCTCTCTGGCCTGCTGCTCTCTC
AACATCACATACAGCTTCAGCTGCCTGGAGGCCAGAAGGAAAGGGCAGTGCAGGGGAGGCCTGAGCCCGACTTAGCCAGCCCTGGCTGTT
GTATTACCAAAGCAGGGTCCATGTTTGCTGCCTTAACCCTGTCTCCTCTCTGTTACTCAGAGGGCCTCATCTCAGACAAGGCCCAGCCTG
CTTTTTCTCAGCCCTGACTTTCTAATGGGCTTTCCCCCCTAGGTCAGTCTTGCTGGATTTGTGCTTTTCTTTTGTGGTTTCTCTGGCCCT
GAGAATAGCATGGGGCTTGTAAACCTTTGGGCTAGATCCCTCCTTTCATTGCTGTTGTCTCTGCTCTTCCCTCTCCTGGCTGTGGTTATT
TATTATTAGTGGTGTGGCACTGGGAGCTGCTCCTAAGGAAGCAGGGAGCAAATCCCACCTTTACCCCACCTTCCTGGGAAAGGCCTCCAA
AGCAAAGGATCTGGACCAGTTTCCCTGCTGTGCTGTGGCCCAGGCCAGAGCCTGTGGGCAGGCAGGCAGGGCATAGCGACAGTGTGGGAC
CTGCCCCCAGCTTCTGCCACGCTTTATGCCCTTGCCTCTCTGGACGCTCTGCACCAACCCCAGGCTACTGAGCCACCTTCCCTCCTCATG
CCTTCCCTGAGCTTTGGTGCATCTCATCTGGACTATGGGTTGTACTGTGACCATCCCAACACCTCACCCTCTGTCTACAAGGAAATGGGA

>5774_5774_7_ARAP3-DIAPH1_ARAP3_chr5_141059112_ENST00000239440_DIAPH1_chr5_140914000_ENST00000518047_length(amino acids)=495AA_BP=1
MPPPLPSGPQQAQCTSWILVACTMVSNLWGLQEPPTEERAEVFVRAGLNTAKKDQEGGEEKKSVQKKKVKELKVLDSKTAQNLSIFLGSF
RMPYQEIKNVILEVNEAVLTESMIQNLIKQMPEPEQLKMLSELKDEYDDLAESEQFGVVMGTVPRLRPRLNAILFKLQFSEQVENIKPEI
VSVTAACEELRKSESFSNLLEITLLVGNYMNAGSRNAGAFGFNISFLCKLRDTKSTDQKMTLLHFLAELCENDYPDVLKFPDELAHVEKA
SRVSAENLQKNLDQMKKQISDVERDVQNFPAATDEKDKFVEKMTSFVKDAQEQYNKLRMMHSNMETLYKELGEYFLFDPKKLSVEEFFMD
LHNFRNMFLQAVKENQKRRETEEKMRRAKLAKEKAEKERLEKQQKREQLIDMNAEGDETGVMDSLLEALQSGAAFRRKRGPRQANRKAGC

--------------------------------------------------------------
>5774_5774_8_ARAP3-DIAPH1_ARAP3_chr5_141059112_ENST00000239440_DIAPH1_chr5_140914000_ENST00000520569_length(transcript)=3930nt_BP=764nt
CTCGGACGAGCGGCGGGCACCCGCGAGCGGACGGCGGCCGCGTAGTGAGCAATGGCCTGAGCCCCCATGGCTGCCCCTCAGGACCTGGAC
ATCGCTGTGTGGCTGGCCACGGTGCACCTGGAGCAGTATGCAGACACGTTCCGACGGCATGGCCTGGCTACAGCAGGTGCAGCCCGGGGC
CTGGGCCACGAGGAGTTGAAGCAGTTGGGCATCAGCGCCACAGGGCACCGGAAACGCATTCTACGCCTGCTACAGACAGGCACCGAAGAG
GGCTCCCTGGATCCCAAATCAGATAGTGCCATGGAACCATCCCCCAGCCCAGCCCCGCAAGCCCAGCCCCCTAAGCCCGTGCCGAAGCCC
AGGACCGTGTTTGGTGGACTCAGTGGCCCTGCCACCACTCAGAGACCTGGGCTGAGCCCAGCCCTCGGGGGACCAGGAGTGTCCAGGAGC
CCAGAGCCCAGCCCAAGGCCTCCTCCTCTCCCCACTTCCTCCTCTGAGCAGTCTTCAGCCCTAAATACTGTGGAGATGATGCCTAATTCC
ATCTACTTCGGCCTGGACTCAAGAGGCAGGGCACAGGCAGCTCAGGACAAGGCCCCAGACAGCTCCCAAATCTCTGCCCCCACCCCTGCC
CTCAGGCCCACAACAGGCACAGTGCACATCATGGATCCTGGTTGCCTGTACTATGGTGTCCAACCTGTGGGGACTCCAGGAGCCCCCGAC
AGAAGAGAGAGCAGAGGTGTTTGTCAGGGCAGGGCTGAACACAGCCAAGAAGGATCAAGAAGGTGGAGAAGAAAAGAAATCTGTGCAAAA
GAAAAAAGTAAAAGAGTTAAAGGTGTTGGATTCAAAGACAGCCCAGAATCTCTCAATCTTTTTGGGTTCCTTCCGCATGCCCTATCAAGA
GATTAAGAATGTCATCCTGGAGGTGAATGAGGCTGTTCTGACTGAGTCTATGATCCAGAACCTCATTAAGCAAATGCCAGAGCCAGAGCA
GTTAAAAATGCTTTCTGAACTGAAGGATGAATATGATGACCTGGCTGAGTCAGAGCAGTTTGGCGTGGTGATGGGCACTGTGCCCCGACT
GCGGCCTCGCCTCAATGCCATTCTCTTCAAGCTACAATTCAGCGAGCAAGTGGAGAATATCAAGCCAGAGATTGTGTCTGTCACTGCTGC
ATGTGAGGAGTTACGTAAGAGTGAGAGCTTTTCCAATCTCCTAGAGATTACCTTGCTTGTTGGAAATTACATGAATGCTGGCTCCAGAAA
TGCTGGTGCTTTTGGCTTCAATATCAGCTTCCTCTGTAAGCTTCGAGACACCAAGTCCACAGATCAGAAGATGACGTTGTTACACTTCTT
GGCTGAGTTGTGTGAGAATGACTATCCCGATGTCCTCAAGTTTCCAGACGAGCTTGCCCATGTGGAGAAAGCCAGCCGAGTTTCTGCTGA
AAACTTGCAAAAGAACCTAGATCAGATGAAGAAACAAATTTCTGATGTGGAACGTGATGTTCAGAATTTCCCAGCTGCCACAGATGAAAA
AGACAAGTTTGTTGAAAAAATGACCAGCTTTGTGAAGGATGCACAGGAACAGTATAACAAGCTGCGGATGATGCATTCTAACATGGAGAC
CCTCTATAAGGAGCTGGGCGAGTACTTCCTCTTTGACCCCAAGAAGTTGTCTGTTGAAGAATTTTTCATGGATCTTCACAATTTTCGGAA
TATGTTTTTGCAAGCAGTCAAGGAGAACCAGAAGCGGCGGGAGACAGAAGAAAAGATGAGGCGAGCAAAACTAGCCAAGGAGAAGGCAGA
GAAGGAGCGGCTAGAGAAGCAGCAGAAGAGAGAGCAACTCATAGACATGAATGCAGAGGGCGATGAGACAGGTGTGATGGACAGTCTTCT
AGAAGCCCTGCAGTCAGGGGCAGCATTCCGACGGAAGAGAGGGCCCCGTCAAGCCAACAGGAAGGCCGGGTGTGCAGTCACATCTCTGCT
AGCTTCGGAGCTGACCAAGGATGATGCCATGGCTGCTGTTCCTGCCAAGGTGTCCAAGAACAGTGAGACATTCCCCACAATCCTTGAGGA
AGCCAAGGAGTTGGTTGGCCGTGCAAGCTAATGTGGGTCCTGTGACCGCGGCAGCTCCTCAGCGGAGCCGCAGACTGTCCTGCCCTGCAG
CATGTGCCTAAAGGCTCAAGGGGATATTCCTCTGGGGTGGCCACTCCCACCACCCTGACCCTGTCTTTCTCTCTGGCCTGCTGCTCTCTC
AACATCACATACAGCTTCAGCTGCCTGGAGGCCAGAAGGAAAGGGCAGTGCAGGGGAGGCCTGAGCCCGACTTAGCCAGCCCTGGCTGTT
GTATTACCAAAGCAGGGTCCATGTTTGCTGCCTTAACCCTGTCTCCTCTCTGTTACTCAGAGGGCCTCATCTCAGACAAGGCCCAGCCTG
CTTTTTCTCAGCCCTGACTTTCTAATGGGCTTTCCCCCCTAGGTCAGTCTTGCTGGATTTGTGCTTTTCTTTTGTGGTTTCTCTGGCCCT
GAGAATAGCATGGGGCTTGTAAACCTTTGGGCTAGATCCCTCCTTTCATTGCTGTTGTCTCTGCTCTTCCCTCTCCTGGCTGTGGTTATT
TATTATTAGTGGTGTGGCACTGGGAGCTGCTCCTAAGGAAGCAGGGAGCAAATCCCACCTTTACCCCACCTTCCTGGGAAAGGCCTCCAA
AGCAAAGGATCTGGACCAGTTTCCCTGCTGTGCTGTGGCCCAGGCCAGAGCCTGTGGGCAGGCAGGCAGGGCATAGCGACAGTGTGGGAC
CTGCCCCCAGCTTCTGCCACGCTTTATGCCCTTGCCTCTCTGGACGCTCTGCACCAACCCCAGGCTACTGAGCCACCTTCCCTCCTCATG
CCTTCCCTGAGCTTTGGTGCATCTCATCTGGACTATGGGTTGTACTGTGACCATCCCAACACCTCACCCTCTGTCTACAAGGAAATGGGA
GGTGGAGCCTCCTGGCTGAGAAATTGTTTTGCAAATGGATCTATTTTTGTATGAAAAAAAAAATTTTTTTAAAGAAAACTGTTCCTTCCC
CCTTTCCCCTCCATAATGTAAGAAGCTTTGGTGGCAGGTTACAGAGTTCTGGGATTTCTTCTCACAGGCCCAATCCTGAATGTGCCCCTG
GACCTTCTGGACCCTTGAGTCCAAGGCAGATCCTCTCTCCCAGGGAATCCGACACAGGAGGAACCCCTTCTCTGGTTGAGCTGGGCCAGG
CCTAAGAGTAGCAGGAACTCTAAGACCACAGAGTTTTTTATAAATGTATAAATGTATCAAGCCAAATGTGCAGATGCTAACTGGACATTC
TGGGGAACTGGGCACCAGGAGTGCCTTCATACACTGTACCCCAGCTCTCTTCTAAAAGAGAAGTGGGTGGGCACACTGAACTGTTTGGTG
GCCCCAACCACAGGAAGCTGCAATTCTCTGGCTTAGGGTGATACTTTTGCCCTCCTTGTGCCCCTCTCAGCTTTCCATCCCCAGCTAGGA
AGAAAGAATGGCACTCTTGGGCTTGGCCCAGAATTAGAGTTATTAGAGCAAGAGAGAGCTTAGGAAGCATGAGGGCAACTATAGTGAGGC
CTTATTGCCAGGAGGGAGGGTTTTGGTTGCTGGCGCTTGTGTATAAAGGGGCAAGAGCAGCTCCTTTGGACTATTCCTGGGAGGACTCTG
ATGCAGGGCGTCTGTTGCTCCCCTGGGTCACCTCCTCCCTGCTCGCTGACATCTGGGGCTTTGACCCTTTCTTTTTTAATCTACTTTTGC
TAAGATGCATTTAATAAAAAAAAAGAGAGAGAGAGAGAGGTGTGAGGGACAAAATGCAAACCTATTTCCCTTGCCTCATAGGCTTCTGGG

>5774_5774_8_ARAP3-DIAPH1_ARAP3_chr5_141059112_ENST00000239440_DIAPH1_chr5_140914000_ENST00000520569_length(amino acids)=495AA_BP=1
MPPPLPSGPQQAQCTSWILVACTMVSNLWGLQEPPTEERAEVFVRAGLNTAKKDQEGGEEKKSVQKKKVKELKVLDSKTAQNLSIFLGSF
RMPYQEIKNVILEVNEAVLTESMIQNLIKQMPEPEQLKMLSELKDEYDDLAESEQFGVVMGTVPRLRPRLNAILFKLQFSEQVENIKPEI
VSVTAACEELRKSESFSNLLEITLLVGNYMNAGSRNAGAFGFNISFLCKLRDTKSTDQKMTLLHFLAELCENDYPDVLKFPDELAHVEKA
SRVSAENLQKNLDQMKKQISDVERDVQNFPAATDEKDKFVEKMTSFVKDAQEQYNKLRMMHSNMETLYKELGEYFLFDPKKLSVEEFFMD
LHNFRNMFLQAVKENQKRRETEEKMRRAKLAKEKAEKERLEKQQKREQLIDMNAEGDETGVMDSLLEALQSGAAFRRKRGPRQANRKAGC

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ARAP3-DIAPH1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ARAP3-DIAPH1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ARAP3-DIAPH1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneARAP3C0019693HIV Infections1CTD_human
HgeneARAP3C4505456HIV Coinfection1CTD_human
TgeneC1852282DEAFNESS, AUTOSOMAL DOMINANT 1 (disorder)10CLINGEN;CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
TgeneC4225261SEIZURES, CORTICAL BLINDNESS, AND MICROCEPHALY SYNDROME4CTD_human;GENOMICS_ENGLAND;ORPHANET
TgeneC0424605Developmental delay (disorder)1GENOMICS_ENGLAND
TgeneC0557874Global developmental delay1GENOMICS_ENGLAND
TgeneC1384666hearing impairment1GENOMICS_ENGLAND
TgeneC3714756Intellectual Disability1GENOMICS_ENGLAND