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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:C6orf106-ANKS1A (FusionGDB2 ID:HG64771TG23294)

Fusion Gene Summary for C6orf106-ANKS1A

check button Fusion gene summary
Fusion gene informationFusion gene name: C6orf106-ANKS1A
Fusion gene ID: hg64771tg23294
HgeneTgene
Gene symbol

C6orf106

ANKS1A

Gene ID

64771

23294

Gene nameinflammation and lipid regulator with UBA-like and NBR1-like domainsankyrin repeat and sterile alpha motif domain containing 1A
SynonymsC6orf106|FP852|dJ391O22.4ANKS1
Cytomap('C6orf106')('ANKS1A')

6p21.31

6p21.31

Type of geneprotein-codingprotein-coding
Descriptionprotein ILRUNinflammation and lipid regulator with UBA-like and NBR1-like domains proteinuncharacterized protein C6orf106ankyrin repeat and SAM domain-containing protein 1AOdinankyrin repeat and SAM domain containing 1
Modification date2020031320200327
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000374023, ENST00000374026, 
ENST00000374021, 
Fusion gene scores* DoF score16 X 9 X 9=129636 X 13 X 15=7020
# samples 2136
** MAII scorelog2(21/1296*10)=-2.6256044852185
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(36/7020*10)=-4.28540221886225
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: C6orf106 [Title/Abstract] AND ANKS1A [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointC6orf106(34664222)-ANKS1A(35021875), # samples:1
C6orf106(34664223)-ANKS1A(35021876), # samples:1
Anticipated loss of major functional domain due to fusion event.C6orf106-ANKS1A seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
C6orf106-ANKS1A seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
C6orf106-ANKS1A seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
C6orf106-ANKS1A seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneC6orf106

GO:0043392

negative regulation of DNA binding

29802199


check buttonFusion gene breakpoints across C6orf106 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across ANKS1A (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4GBMTCGA-06-0129-01AC6orf106chr6

34664223

-ANKS1Achr6

35021876

+
ChimerDB4GBMTCGA-06-0129C6orf106chr6

34664222

-ANKS1Achr6

35021875

+


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Fusion Gene ORF analysis for C6orf106-ANKS1A

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000374023ENST00000470698C6orf106chr6

34664223

-ANKS1Achr6

35021876

+
5CDS-intronENST00000374023ENST00000470698C6orf106chr6

34664222

-ANKS1Achr6

35021875

+
5CDS-intronENST00000374023ENST00000535627C6orf106chr6

34664223

-ANKS1Achr6

35021876

+
5CDS-intronENST00000374023ENST00000535627C6orf106chr6

34664222

-ANKS1Achr6

35021875

+
5CDS-intronENST00000374026ENST00000470698C6orf106chr6

34664223

-ANKS1Achr6

35021876

+
5CDS-intronENST00000374026ENST00000470698C6orf106chr6

34664222

-ANKS1Achr6

35021875

+
5CDS-intronENST00000374026ENST00000535627C6orf106chr6

34664223

-ANKS1Achr6

35021876

+
5CDS-intronENST00000374026ENST00000535627C6orf106chr6

34664222

-ANKS1Achr6

35021875

+
In-frameENST00000374023ENST00000360359C6orf106chr6

34664223

-ANKS1Achr6

35021876

+
In-frameENST00000374023ENST00000360359C6orf106chr6

34664222

-ANKS1Achr6

35021875

+
In-frameENST00000374026ENST00000360359C6orf106chr6

34664223

-ANKS1Achr6

35021876

+
In-frameENST00000374026ENST00000360359C6orf106chr6

34664222

-ANKS1Achr6

35021875

+
intron-3CDSENST00000374021ENST00000360359C6orf106chr6

34664223

-ANKS1Achr6

35021876

+
intron-3CDSENST00000374021ENST00000360359C6orf106chr6

34664222

-ANKS1Achr6

35021875

+
intron-intronENST00000374021ENST00000470698C6orf106chr6

34664223

-ANKS1Achr6

35021876

+
intron-intronENST00000374021ENST00000470698C6orf106chr6

34664222

-ANKS1Achr6

35021875

+
intron-intronENST00000374021ENST00000535627C6orf106chr6

34664223

-ANKS1Achr6

35021876

+
intron-intronENST00000374021ENST00000535627C6orf106chr6

34664222

-ANKS1Achr6

35021875

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000374023C6orf106chr634664222-ENST00000360359ANKS1Achr635021875+45904022941796500
ENST00000374026C6orf106chr634664222-ENST00000360359ANKS1Achr635021875+46024143061808500
ENST00000374023C6orf106chr634664223-ENST00000360359ANKS1Achr635021876+45904022941796500
ENST00000374026C6orf106chr634664223-ENST00000360359ANKS1Achr635021876+46024143061808500

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000374023ENST00000360359C6orf106chr634664222-ANKS1Achr635021875+0.0091782080.9908217
ENST00000374026ENST00000360359C6orf106chr634664222-ANKS1Achr635021875+0.0092653560.9907347
ENST00000374023ENST00000360359C6orf106chr634664223-ANKS1Achr635021876+0.0091782080.9908217
ENST00000374026ENST00000360359C6orf106chr634664223-ANKS1Achr635021876+0.0092653560.9907347

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Fusion Genomic Features for C6orf106-ANKS1A


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
C6orf106chr634664222-ANKS1Achr635021875+4.79E-111
C6orf106chr634664222-ANKS1Achr635021875+4.79E-111
C6orf106chr634664222-ANKS1Achr635021875+4.79E-111
C6orf106chr634664222-ANKS1Achr635021875+4.79E-111

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for C6orf106-ANKS1A


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr6:34664222/chr6:35021875)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneANKS1Achr6:34664222chr6:35021875ENST000003603591024696_7626701135.0DomainSAM 1
TgeneANKS1Achr6:34664222chr6:35021875ENST000003603591024770_8376701135.0DomainSAM 2
TgeneANKS1Achr6:34664222chr6:35021875ENST000003603591024936_10916701135.0DomainPID
TgeneANKS1Achr6:34664223chr6:35021876ENST000003603591024696_7626701135.0DomainSAM 1
TgeneANKS1Achr6:34664223chr6:35021876ENST000003603591024770_8376701135.0DomainSAM 2
TgeneANKS1Achr6:34664223chr6:35021876ENST000003603591024936_10916701135.0DomainPID

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneANKS1Achr6:34664222chr6:35021875ENST0000036035910242_556701135.0Compositional biasNote=Gly-rich
TgeneANKS1Achr6:34664223chr6:35021876ENST0000036035910242_556701135.0Compositional biasNote=Gly-rich
TgeneANKS1Achr6:34664222chr6:35021875ENST000003603591024112_1416701135.0RepeatNote=ANK 2
TgeneANKS1Achr6:34664222chr6:35021875ENST000003603591024148_1776701135.0RepeatNote=ANK 3
TgeneANKS1Achr6:34664222chr6:35021875ENST000003603591024181_2106701135.0RepeatNote=ANK 4
TgeneANKS1Achr6:34664222chr6:35021875ENST000003603591024214_2436701135.0RepeatNote=ANK 5
TgeneANKS1Achr6:34664222chr6:35021875ENST000003603591024246_2756701135.0RepeatNote=ANK 6
TgeneANKS1Achr6:34664222chr6:35021875ENST00000360359102479_1086701135.0RepeatNote=ANK 1
TgeneANKS1Achr6:34664223chr6:35021876ENST000003603591024112_1416701135.0RepeatNote=ANK 2
TgeneANKS1Achr6:34664223chr6:35021876ENST000003603591024148_1776701135.0RepeatNote=ANK 3
TgeneANKS1Achr6:34664223chr6:35021876ENST000003603591024181_2106701135.0RepeatNote=ANK 4
TgeneANKS1Achr6:34664223chr6:35021876ENST000003603591024214_2436701135.0RepeatNote=ANK 5
TgeneANKS1Achr6:34664223chr6:35021876ENST000003603591024246_2756701135.0RepeatNote=ANK 6
TgeneANKS1Achr6:34664223chr6:35021876ENST00000360359102479_1086701135.0RepeatNote=ANK 1


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Fusion Gene Sequence for C6orf106-ANKS1A


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>11904_11904_1_C6orf106-ANKS1A_C6orf106_chr6_34664222_ENST00000374023_ANKS1A_chr6_35021875_ENST00000360359_length(transcript)=4590nt_BP=402nt
GGCGGAGTGGCGAGAGGCGAGAGGCGGCGGAGGCGGCGGAGCTGGGGGGGGTGGGAGGGGGGGGAGAGTGAGTGAGTGGCAGAGTGAGTT
TACCCCTATGAGACTGTGAGAGGCCCGGGGCCTACCTCAAAGGAGCGGGGTCGCGAAGCTAGCTAGCAGCGGCCCCCCTCCAGGTCCCCG
GGCCCGGCGGCGCGGCGGCGGCTTGGTTGTGAAGAGGCGGGGAAGCGGGTGTCCGGTCCCCGCCATGGAGGGCATGGACGTAGACCTGGA
CCCGGAGCTGATGCAGAAGTTCAGCTGCCTGGGCACCACCGACAAGGACGTGCTCATCTCCGAGTTCCAGAGGCTGCTCGGCTTCCAGCT
CAATCCTGCCGGTTGCGCCTTCTTCCTGGACATGACCAACTGATTGAGAAAATCATGAGTTCTATTGGAGAAGGGATTGACTTTTCTCAG
GAACGGCAGAAGATCTCAGGTTTACGGACGCTGGAGCAGAGTGTCGGGGAGTGGCTGGAGTCGATTGGGCTGCAGCAGTATGAGAGCAAG
TTGCTTCTGAATGGCTTTGACGATGTCCACTTCCTGGGGTCTAATGTGATGGAAGAGCAGGACCTGCGGGACATCGGCATCAGCGACCCA
CAGCACCGGCGGAAGCTGCTCCAGGCGGCACGCTCCCTACCCAAGGTGAAGGCTCTGGGTTATGACGGGAACAGCCCCCCTAGCGTGCCC
TCCTGGCTGGACTCCCTGGGGCTGCAGGACTACGTCCATTCCTTCTTGTCAAGTGGTTACAGCTCCATTGACACCGTGAAGAACCTCTGG
GAGCTAGAGCTCGTCAATGTCCTGAAGGTCCAGCTGCTCGGCCATCGCAAGCGCATCATCGCCTCCCTCGCAGACAGACCGTACGAGGAG
CCGCCCCAGAAGCCCCCCAGATTCTCCCAGCTGAGGTGCCAAGATTTGCTCTCCCAGACGTCATCCCCACTGAGTCAGAATGATTCCTGC
ACTGGGCGGTCGGCAGATCTGCTGCTGCCTCCAGGGGACACAGGCAGGAGGCGCCATGACAGTCTCCATGACCCTGCGGCACCCTCCCGA
GCGGAGCGCTTCAGGATCCAGGAGGAGCACCGTGAGGCCAAGCTGACCCTGCGGCCCCCGAGCCTGGCAGCCCCCTACGCCCCAGTGCAG
AGTTGGCAACACCAGCCAGAGAAACTCATCTTCGAGTCCTGTGGTTATGAAGCCAATTATCTGGGCTCCATGCTGATCAAAGATCTGCGA
GGGACAGAATCCACGCAAGACGCCTGTGCCAAGATGCGGAAATCTACGGAGCACATGAAGAAGATCCCCACCATCATCCTGTCCATCACA
TACAAAGGTGTCAAGTTCATCGATGCCTCCAACAAGAACGTCATTGCAGAGCACGAGATCCGGAACATTTCCTGTGCGGCCCAGGACCCG
GAGGACCTCTGTACCTTTGCCTACATCACCAAGGACCTGCAGACCAGCCACCACTATTGCCATGTGTTCAGCACCGTGGATGTGAACCTG
ACCTACGAGATCATCCTGACGCTGGGGCAGGCCTTCGAAGTGGCCTATCAGTTGGCCCTGCAGGCCCAGAAGTCCAGGGCGACGGGCGCC
TCTGCAGCTGAGATGATTGAAACAAAATCTTCCAAACCGGTGCCTAAGCCTCGGGTCGGCGTGAGGAAATCCGCACTGGAACCACCTGAT
ATGGACCAAGATGCCCAATCCCATGCCAGTGTCTCCTGGGTTGTGGACCCCAAACCAGACTCTAAGCGGAGCCTCAGCACCAACTGAGCC
ACTGAGGAACCACACTGTGCTGCGGAAACATAGACGTGGGGGCATAGGCTCCCACTGCCACCACCGCCATCGCCTCACCTGCAGCTCTGA
AGACCCAGGCCTCACCTCCGCCTGCAGGACCTCCTCTTGGCCACTTGGCCTGGGCCTGCCACCACCACGTCCTGCAGAACGAGCCCTGCC
TTGGCTGTGGAGAAGCACTCCAGGCCGCTAGCAGATGGGACTGGCATTCCAGAGGGTCAAGAAGTGACTTGTTCAGAACACATTGTTTTT
AACAGAAAAAAAATCTTTTTATAAAATGAACTTTTAACACTTGGCTCAAACCTCTAGGTCATACTGCCAATCTTTAGACAAATGGCCATG
GGGCAGAGGACAGGGGAGCTGAGGTTGGTTCAGAGGCCAGCCTGCATAGCCTCTGTCCTCAGGACGGAACTTGGGTGCAGCTCAGTGGGT
CGGAAGAGAAGGCGGTGGCCTGTGGGTGAGGGGAACGGAGCAGGCTCAGGCAGAATTGAGTACGGTGCGTCTGCTTTTCAAACCCAACCA
TATCAGCTGCTGCTCTTTATGAACTGCCCAACTTCCTGTCCCTTTCAGGGGCTAGACACAGGCTTCTCGTAAGAACACAGCCTTAGAGGC
ACCTGAGCAACTCAAAGGTTTCCGGTCCATTTCTGGGGTTCCCGATGGGAAGGTTCAGTGGCCAAATGAAGATAAGTGTGCAGTTTCTAG
TGCTGGGAAGTCTTAGCCAGCACCAGAGCGCCAGGCCTCTCCCTGGCCTCTTACCTGTCAGTGATCGGAGCACTGCCCTGGGCTGGCCGG
CGCCGTACTGCCTGCGTTGTGTCAGAGAATAGGAAAAGCAGCTTTGTTTGGGGCATTAATGCTTGGAGTGGGGTCAGCTAAGGTTGCTAC
TTGCCAATTTGTGATTTGTCTAATCAGCCTGTGTGATTGGGGCTCATTTTGATTCTCTGAATTATCGGTTTGACGGTTACACTTGGCTGC
TGGGCCCATCCCTGGCCCCCGGTGTGGAAAAGGCTAAATAAGGTGACAGTGCATCGATGCTCCCCCGCGTGGCCTTTGGGGCAGGCTGGC
ATCCCGGTGCGCCTCTGCTTCTTAAGCTTTCCTGCTGCTCGCTTTGTTTTTAAAAGTAACTTGGGTTGCATTCTTCCCTCTGGACTAGAG
TAGAAATGCAGGGGAAACTGCTGTGGATTTGAGAGGCAAAGTTGGCTCAGCTGTGTGCCCAGTTCCTCCTGTGGGCACTTTAGCAGGCTC
CGAGCTTTCCTGGCATAGGTCAATCAGGTCCCAGGATGAATAATCCAGGCTTCAGCAACACTCCTCTTTCCCAGCCAGCAAAGGCTGTGA
ATTTGAATTCTTTGTTGGTATGTATGTGCAGGGAGTACTGTTAGGCACATTCTTAACCCATGTGGTTGGCCAGAAATCAGAAGTGGGGCT
GTGTCTCTGACTGGCTAGAGGCCAGGCCTTGTGGGTTTCTATCTGCTAAGCACCCAGCAGGTTGGGGCCTGGGACTCAGCTCTCTCTGCG
GTAGAGGCAGGCCCTCCTCCACTTCTTGGTACTAAACGAAGATCTCGACACCTTGCAGTTTTACTTCATTTCCTGCCCCTTTCAGGGCCT
GTGAGGATGCCCATGAGCTACCGCTGTACAGTTCTCGGCCCCGGCTTTCTTCCAAGAGTTGACCAGGAACCCTAAAGCATCCAGAGTAGA
CTGCGCTGCCACTGCGCACATGCTGGTGCCCGTCTTCCTCCTAAGGGGCCAGGCCACATCCAAGTGGGCCTCTGTCGGGGGCGGGGCGGT
AGGTCCGAAAGAAACCGCAGACACTACGATGCACTCCTCAAGCTGTCTTTTGTGCTTAGATCATCCATAGGTGTTTCTTCTGCTTGAAGC
TGCTATATCATCTTTATTTATTCAGGGTATTTTCATATTGGAAGCCTTGGCTAGTCTGCTCTAGCTCTGGGTTCTGTTTAGAGATTGGTT
TATTTCTGAATATTCAAGAAAGGAAAATGACTGGGCCTTTCTTTCTTTTCTTCTCCTCTGGGATGGGTAGTCTCCCTTTCCTAGAAAGGT
TATTATAACTTTAAGGACAGGCTTCAAGTGGGAAGGCCCCTACTTTTGCACTTCTCCAAGTGCAGGTCACACCAGGGGCAGACCCTGTCG
CTGCGTTTCTGAACTGTGAAGGAGCCCATTCGGGTGGGAGACTTCAGATGGGCTCAGTACCTGTCCCAGCCACAGGCTTCTTGTCCACCT
CTTCTCCCCTGCCCACCAGCTGCTCAGCGCATAAGACCTTCCCGACAGGCTCTGCGTGTGCAGCTCTCTGCGTCCCTCCTGGGCCCTCCA
GCGTCAGACACTAATGGGAGTTCCCGAGATGCTCGGGTTTGAGCAGGGAGCAGGCAGAGCTGCAGTCAGAGACATTAGAAAACCAGTCTG
AATTGGGTCTGTCTTTGAGATGCCCAGGCCAGCAGAAAGCAGCTCAGAAGTATTGTTGCTCATGGTGTGGCAATGGACTGAACTGTAATG
AAAATGTTATTTAATCTTTGTCTCTGTATTTTGATACTTGAATGACTTTCCCTTTTGTTTTACTGTATATAAAATTGTTAATCTGTCTGA
TTTTGTCTGAATTATAAACACTTTGAGGTACCAAACATAACCAATCTGTGCAACAACATAGACTGACCTCAGTACCCAAGAGAGTGTAAA
TATTTCTGGGCTTCCAGCTTTGGTTTTGTTATTTTCATAACTGTACACAACTTAGAACAGACTGAATTAATAAATGAGAAGCGACATGAA


>11904_11904_1_C6orf106-ANKS1A_C6orf106_chr6_34664222_ENST00000374023_ANKS1A_chr6_35021875_ENST00000360359_length(amino acids)=500AA_BP=36
MPGHHRQGRAHLRVPEAARLPAQSCRLRLLPGHDQLIEKIMSSIGEGIDFSQERQKISGLRTLEQSVGEWLESIGLQQYESKLLLNGFDD
VHFLGSNVMEEQDLRDIGISDPQHRRKLLQAARSLPKVKALGYDGNSPPSVPSWLDSLGLQDYVHSFLSSGYSSIDTVKNLWELELVNVL
KVQLLGHRKRIIASLADRPYEEPPQKPPRFSQLRCQDLLSQTSSPLSQNDSCTGRSADLLLPPGDTGRRRHDSLHDPAAPSRAERFRIQE
EHREAKLTLRPPSLAAPYAPVQSWQHQPEKLIFESCGYEANYLGSMLIKDLRGTESTQDACAKMRKSTEHMKKIPTIILSITYKGVKFID
ASNKNVIAEHEIRNISCAAQDPEDLCTFAYITKDLQTSHHYCHVFSTVDVNLTYEIILTLGQAFEVAYQLALQAQKSRATGASAAEMIET
KSSKPVPKPRVGVRKSALEPPDMDQDAQSHASVSWVVDPKPDSKRSLSTN

--------------------------------------------------------------
>11904_11904_2_C6orf106-ANKS1A_C6orf106_chr6_34664222_ENST00000374026_ANKS1A_chr6_35021875_ENST00000360359_length(transcript)=4602nt_BP=414nt
GGAGGCGGAGGCGGCGGAGTGGCGAGAGGCGAGAGGCGGCGGAGGCGGCGGAGCTGGGGGGGGTGGGAGGGGGGGGAGAGTGAGTGAGTG
GCAGAGTGAGTTTACCCCTATGAGACTGTGAGAGGCCCGGGGCCTACCTCAAAGGAGCGGGGTCGCGAAGCTAGCTAGCAGCGGCCCCCC
TCCAGGTCCCCGGGCCCGGCGGCGCGGCGGCGGCTTGGTTGTGAAGAGGCGGGGAAGCGGGTGTCCGGTCCCCGCCATGGAGGGCATGGA
CGTAGACCTGGACCCGGAGCTGATGCAGAAGTTCAGCTGCCTGGGCACCACCGACAAGGACGTGCTCATCTCCGAGTTCCAGAGGCTGCT
CGGCTTCCAGCTCAATCCTGCCGGTTGCGCCTTCTTCCTGGACATGACCAACTGATTGAGAAAATCATGAGTTCTATTGGAGAAGGGATT
GACTTTTCTCAGGAACGGCAGAAGATCTCAGGTTTACGGACGCTGGAGCAGAGTGTCGGGGAGTGGCTGGAGTCGATTGGGCTGCAGCAG
TATGAGAGCAAGTTGCTTCTGAATGGCTTTGACGATGTCCACTTCCTGGGGTCTAATGTGATGGAAGAGCAGGACCTGCGGGACATCGGC
ATCAGCGACCCACAGCACCGGCGGAAGCTGCTCCAGGCGGCACGCTCCCTACCCAAGGTGAAGGCTCTGGGTTATGACGGGAACAGCCCC
CCTAGCGTGCCCTCCTGGCTGGACTCCCTGGGGCTGCAGGACTACGTCCATTCCTTCTTGTCAAGTGGTTACAGCTCCATTGACACCGTG
AAGAACCTCTGGGAGCTAGAGCTCGTCAATGTCCTGAAGGTCCAGCTGCTCGGCCATCGCAAGCGCATCATCGCCTCCCTCGCAGACAGA
CCGTACGAGGAGCCGCCCCAGAAGCCCCCCAGATTCTCCCAGCTGAGGTGCCAAGATTTGCTCTCCCAGACGTCATCCCCACTGAGTCAG
AATGATTCCTGCACTGGGCGGTCGGCAGATCTGCTGCTGCCTCCAGGGGACACAGGCAGGAGGCGCCATGACAGTCTCCATGACCCTGCG
GCACCCTCCCGAGCGGAGCGCTTCAGGATCCAGGAGGAGCACCGTGAGGCCAAGCTGACCCTGCGGCCCCCGAGCCTGGCAGCCCCCTAC
GCCCCAGTGCAGAGTTGGCAACACCAGCCAGAGAAACTCATCTTCGAGTCCTGTGGTTATGAAGCCAATTATCTGGGCTCCATGCTGATC
AAAGATCTGCGAGGGACAGAATCCACGCAAGACGCCTGTGCCAAGATGCGGAAATCTACGGAGCACATGAAGAAGATCCCCACCATCATC
CTGTCCATCACATACAAAGGTGTCAAGTTCATCGATGCCTCCAACAAGAACGTCATTGCAGAGCACGAGATCCGGAACATTTCCTGTGCG
GCCCAGGACCCGGAGGACCTCTGTACCTTTGCCTACATCACCAAGGACCTGCAGACCAGCCACCACTATTGCCATGTGTTCAGCACCGTG
GATGTGAACCTGACCTACGAGATCATCCTGACGCTGGGGCAGGCCTTCGAAGTGGCCTATCAGTTGGCCCTGCAGGCCCAGAAGTCCAGG
GCGACGGGCGCCTCTGCAGCTGAGATGATTGAAACAAAATCTTCCAAACCGGTGCCTAAGCCTCGGGTCGGCGTGAGGAAATCCGCACTG
GAACCACCTGATATGGACCAAGATGCCCAATCCCATGCCAGTGTCTCCTGGGTTGTGGACCCCAAACCAGACTCTAAGCGGAGCCTCAGC
ACCAACTGAGCCACTGAGGAACCACACTGTGCTGCGGAAACATAGACGTGGGGGCATAGGCTCCCACTGCCACCACCGCCATCGCCTCAC
CTGCAGCTCTGAAGACCCAGGCCTCACCTCCGCCTGCAGGACCTCCTCTTGGCCACTTGGCCTGGGCCTGCCACCACCACGTCCTGCAGA
ACGAGCCCTGCCTTGGCTGTGGAGAAGCACTCCAGGCCGCTAGCAGATGGGACTGGCATTCCAGAGGGTCAAGAAGTGACTTGTTCAGAA
CACATTGTTTTTAACAGAAAAAAAATCTTTTTATAAAATGAACTTTTAACACTTGGCTCAAACCTCTAGGTCATACTGCCAATCTTTAGA
CAAATGGCCATGGGGCAGAGGACAGGGGAGCTGAGGTTGGTTCAGAGGCCAGCCTGCATAGCCTCTGTCCTCAGGACGGAACTTGGGTGC
AGCTCAGTGGGTCGGAAGAGAAGGCGGTGGCCTGTGGGTGAGGGGAACGGAGCAGGCTCAGGCAGAATTGAGTACGGTGCGTCTGCTTTT
CAAACCCAACCATATCAGCTGCTGCTCTTTATGAACTGCCCAACTTCCTGTCCCTTTCAGGGGCTAGACACAGGCTTCTCGTAAGAACAC
AGCCTTAGAGGCACCTGAGCAACTCAAAGGTTTCCGGTCCATTTCTGGGGTTCCCGATGGGAAGGTTCAGTGGCCAAATGAAGATAAGTG
TGCAGTTTCTAGTGCTGGGAAGTCTTAGCCAGCACCAGAGCGCCAGGCCTCTCCCTGGCCTCTTACCTGTCAGTGATCGGAGCACTGCCC
TGGGCTGGCCGGCGCCGTACTGCCTGCGTTGTGTCAGAGAATAGGAAAAGCAGCTTTGTTTGGGGCATTAATGCTTGGAGTGGGGTCAGC
TAAGGTTGCTACTTGCCAATTTGTGATTTGTCTAATCAGCCTGTGTGATTGGGGCTCATTTTGATTCTCTGAATTATCGGTTTGACGGTT
ACACTTGGCTGCTGGGCCCATCCCTGGCCCCCGGTGTGGAAAAGGCTAAATAAGGTGACAGTGCATCGATGCTCCCCCGCGTGGCCTTTG
GGGCAGGCTGGCATCCCGGTGCGCCTCTGCTTCTTAAGCTTTCCTGCTGCTCGCTTTGTTTTTAAAAGTAACTTGGGTTGCATTCTTCCC
TCTGGACTAGAGTAGAAATGCAGGGGAAACTGCTGTGGATTTGAGAGGCAAAGTTGGCTCAGCTGTGTGCCCAGTTCCTCCTGTGGGCAC
TTTAGCAGGCTCCGAGCTTTCCTGGCATAGGTCAATCAGGTCCCAGGATGAATAATCCAGGCTTCAGCAACACTCCTCTTTCCCAGCCAG
CAAAGGCTGTGAATTTGAATTCTTTGTTGGTATGTATGTGCAGGGAGTACTGTTAGGCACATTCTTAACCCATGTGGTTGGCCAGAAATC
AGAAGTGGGGCTGTGTCTCTGACTGGCTAGAGGCCAGGCCTTGTGGGTTTCTATCTGCTAAGCACCCAGCAGGTTGGGGCCTGGGACTCA
GCTCTCTCTGCGGTAGAGGCAGGCCCTCCTCCACTTCTTGGTACTAAACGAAGATCTCGACACCTTGCAGTTTTACTTCATTTCCTGCCC
CTTTCAGGGCCTGTGAGGATGCCCATGAGCTACCGCTGTACAGTTCTCGGCCCCGGCTTTCTTCCAAGAGTTGACCAGGAACCCTAAAGC
ATCCAGAGTAGACTGCGCTGCCACTGCGCACATGCTGGTGCCCGTCTTCCTCCTAAGGGGCCAGGCCACATCCAAGTGGGCCTCTGTCGG
GGGCGGGGCGGTAGGTCCGAAAGAAACCGCAGACACTACGATGCACTCCTCAAGCTGTCTTTTGTGCTTAGATCATCCATAGGTGTTTCT
TCTGCTTGAAGCTGCTATATCATCTTTATTTATTCAGGGTATTTTCATATTGGAAGCCTTGGCTAGTCTGCTCTAGCTCTGGGTTCTGTT
TAGAGATTGGTTTATTTCTGAATATTCAAGAAAGGAAAATGACTGGGCCTTTCTTTCTTTTCTTCTCCTCTGGGATGGGTAGTCTCCCTT
TCCTAGAAAGGTTATTATAACTTTAAGGACAGGCTTCAAGTGGGAAGGCCCCTACTTTTGCACTTCTCCAAGTGCAGGTCACACCAGGGG
CAGACCCTGTCGCTGCGTTTCTGAACTGTGAAGGAGCCCATTCGGGTGGGAGACTTCAGATGGGCTCAGTACCTGTCCCAGCCACAGGCT
TCTTGTCCACCTCTTCTCCCCTGCCCACCAGCTGCTCAGCGCATAAGACCTTCCCGACAGGCTCTGCGTGTGCAGCTCTCTGCGTCCCTC
CTGGGCCCTCCAGCGTCAGACACTAATGGGAGTTCCCGAGATGCTCGGGTTTGAGCAGGGAGCAGGCAGAGCTGCAGTCAGAGACATTAG
AAAACCAGTCTGAATTGGGTCTGTCTTTGAGATGCCCAGGCCAGCAGAAAGCAGCTCAGAAGTATTGTTGCTCATGGTGTGGCAATGGAC
TGAACTGTAATGAAAATGTTATTTAATCTTTGTCTCTGTATTTTGATACTTGAATGACTTTCCCTTTTGTTTTACTGTATATAAAATTGT
TAATCTGTCTGATTTTGTCTGAATTATAAACACTTTGAGGTACCAAACATAACCAATCTGTGCAACAACATAGACTGACCTCAGTACCCA
AGAGAGTGTAAATATTTCTGGGCTTCCAGCTTTGGTTTTGTTATTTTCATAACTGTACACAACTTAGAACAGACTGAATTAATAAATGAG
AAGCGACATGAA

>11904_11904_2_C6orf106-ANKS1A_C6orf106_chr6_34664222_ENST00000374026_ANKS1A_chr6_35021875_ENST00000360359_length(amino acids)=500AA_BP=36
MPGHHRQGRAHLRVPEAARLPAQSCRLRLLPGHDQLIEKIMSSIGEGIDFSQERQKISGLRTLEQSVGEWLESIGLQQYESKLLLNGFDD
VHFLGSNVMEEQDLRDIGISDPQHRRKLLQAARSLPKVKALGYDGNSPPSVPSWLDSLGLQDYVHSFLSSGYSSIDTVKNLWELELVNVL
KVQLLGHRKRIIASLADRPYEEPPQKPPRFSQLRCQDLLSQTSSPLSQNDSCTGRSADLLLPPGDTGRRRHDSLHDPAAPSRAERFRIQE
EHREAKLTLRPPSLAAPYAPVQSWQHQPEKLIFESCGYEANYLGSMLIKDLRGTESTQDACAKMRKSTEHMKKIPTIILSITYKGVKFID
ASNKNVIAEHEIRNISCAAQDPEDLCTFAYITKDLQTSHHYCHVFSTVDVNLTYEIILTLGQAFEVAYQLALQAQKSRATGASAAEMIET
KSSKPVPKPRVGVRKSALEPPDMDQDAQSHASVSWVVDPKPDSKRSLSTN

--------------------------------------------------------------
>11904_11904_3_C6orf106-ANKS1A_C6orf106_chr6_34664223_ENST00000374023_ANKS1A_chr6_35021876_ENST00000360359_length(transcript)=4590nt_BP=402nt
GGCGGAGTGGCGAGAGGCGAGAGGCGGCGGAGGCGGCGGAGCTGGGGGGGGTGGGAGGGGGGGGAGAGTGAGTGAGTGGCAGAGTGAGTT
TACCCCTATGAGACTGTGAGAGGCCCGGGGCCTACCTCAAAGGAGCGGGGTCGCGAAGCTAGCTAGCAGCGGCCCCCCTCCAGGTCCCCG
GGCCCGGCGGCGCGGCGGCGGCTTGGTTGTGAAGAGGCGGGGAAGCGGGTGTCCGGTCCCCGCCATGGAGGGCATGGACGTAGACCTGGA
CCCGGAGCTGATGCAGAAGTTCAGCTGCCTGGGCACCACCGACAAGGACGTGCTCATCTCCGAGTTCCAGAGGCTGCTCGGCTTCCAGCT
CAATCCTGCCGGTTGCGCCTTCTTCCTGGACATGACCAACTGATTGAGAAAATCATGAGTTCTATTGGAGAAGGGATTGACTTTTCTCAG
GAACGGCAGAAGATCTCAGGTTTACGGACGCTGGAGCAGAGTGTCGGGGAGTGGCTGGAGTCGATTGGGCTGCAGCAGTATGAGAGCAAG
TTGCTTCTGAATGGCTTTGACGATGTCCACTTCCTGGGGTCTAATGTGATGGAAGAGCAGGACCTGCGGGACATCGGCATCAGCGACCCA
CAGCACCGGCGGAAGCTGCTCCAGGCGGCACGCTCCCTACCCAAGGTGAAGGCTCTGGGTTATGACGGGAACAGCCCCCCTAGCGTGCCC
TCCTGGCTGGACTCCCTGGGGCTGCAGGACTACGTCCATTCCTTCTTGTCAAGTGGTTACAGCTCCATTGACACCGTGAAGAACCTCTGG
GAGCTAGAGCTCGTCAATGTCCTGAAGGTCCAGCTGCTCGGCCATCGCAAGCGCATCATCGCCTCCCTCGCAGACAGACCGTACGAGGAG
CCGCCCCAGAAGCCCCCCAGATTCTCCCAGCTGAGGTGCCAAGATTTGCTCTCCCAGACGTCATCCCCACTGAGTCAGAATGATTCCTGC
ACTGGGCGGTCGGCAGATCTGCTGCTGCCTCCAGGGGACACAGGCAGGAGGCGCCATGACAGTCTCCATGACCCTGCGGCACCCTCCCGA
GCGGAGCGCTTCAGGATCCAGGAGGAGCACCGTGAGGCCAAGCTGACCCTGCGGCCCCCGAGCCTGGCAGCCCCCTACGCCCCAGTGCAG
AGTTGGCAACACCAGCCAGAGAAACTCATCTTCGAGTCCTGTGGTTATGAAGCCAATTATCTGGGCTCCATGCTGATCAAAGATCTGCGA
GGGACAGAATCCACGCAAGACGCCTGTGCCAAGATGCGGAAATCTACGGAGCACATGAAGAAGATCCCCACCATCATCCTGTCCATCACA
TACAAAGGTGTCAAGTTCATCGATGCCTCCAACAAGAACGTCATTGCAGAGCACGAGATCCGGAACATTTCCTGTGCGGCCCAGGACCCG
GAGGACCTCTGTACCTTTGCCTACATCACCAAGGACCTGCAGACCAGCCACCACTATTGCCATGTGTTCAGCACCGTGGATGTGAACCTG
ACCTACGAGATCATCCTGACGCTGGGGCAGGCCTTCGAAGTGGCCTATCAGTTGGCCCTGCAGGCCCAGAAGTCCAGGGCGACGGGCGCC
TCTGCAGCTGAGATGATTGAAACAAAATCTTCCAAACCGGTGCCTAAGCCTCGGGTCGGCGTGAGGAAATCCGCACTGGAACCACCTGAT
ATGGACCAAGATGCCCAATCCCATGCCAGTGTCTCCTGGGTTGTGGACCCCAAACCAGACTCTAAGCGGAGCCTCAGCACCAACTGAGCC
ACTGAGGAACCACACTGTGCTGCGGAAACATAGACGTGGGGGCATAGGCTCCCACTGCCACCACCGCCATCGCCTCACCTGCAGCTCTGA
AGACCCAGGCCTCACCTCCGCCTGCAGGACCTCCTCTTGGCCACTTGGCCTGGGCCTGCCACCACCACGTCCTGCAGAACGAGCCCTGCC
TTGGCTGTGGAGAAGCACTCCAGGCCGCTAGCAGATGGGACTGGCATTCCAGAGGGTCAAGAAGTGACTTGTTCAGAACACATTGTTTTT
AACAGAAAAAAAATCTTTTTATAAAATGAACTTTTAACACTTGGCTCAAACCTCTAGGTCATACTGCCAATCTTTAGACAAATGGCCATG
GGGCAGAGGACAGGGGAGCTGAGGTTGGTTCAGAGGCCAGCCTGCATAGCCTCTGTCCTCAGGACGGAACTTGGGTGCAGCTCAGTGGGT
CGGAAGAGAAGGCGGTGGCCTGTGGGTGAGGGGAACGGAGCAGGCTCAGGCAGAATTGAGTACGGTGCGTCTGCTTTTCAAACCCAACCA
TATCAGCTGCTGCTCTTTATGAACTGCCCAACTTCCTGTCCCTTTCAGGGGCTAGACACAGGCTTCTCGTAAGAACACAGCCTTAGAGGC
ACCTGAGCAACTCAAAGGTTTCCGGTCCATTTCTGGGGTTCCCGATGGGAAGGTTCAGTGGCCAAATGAAGATAAGTGTGCAGTTTCTAG
TGCTGGGAAGTCTTAGCCAGCACCAGAGCGCCAGGCCTCTCCCTGGCCTCTTACCTGTCAGTGATCGGAGCACTGCCCTGGGCTGGCCGG
CGCCGTACTGCCTGCGTTGTGTCAGAGAATAGGAAAAGCAGCTTTGTTTGGGGCATTAATGCTTGGAGTGGGGTCAGCTAAGGTTGCTAC
TTGCCAATTTGTGATTTGTCTAATCAGCCTGTGTGATTGGGGCTCATTTTGATTCTCTGAATTATCGGTTTGACGGTTACACTTGGCTGC
TGGGCCCATCCCTGGCCCCCGGTGTGGAAAAGGCTAAATAAGGTGACAGTGCATCGATGCTCCCCCGCGTGGCCTTTGGGGCAGGCTGGC
ATCCCGGTGCGCCTCTGCTTCTTAAGCTTTCCTGCTGCTCGCTTTGTTTTTAAAAGTAACTTGGGTTGCATTCTTCCCTCTGGACTAGAG
TAGAAATGCAGGGGAAACTGCTGTGGATTTGAGAGGCAAAGTTGGCTCAGCTGTGTGCCCAGTTCCTCCTGTGGGCACTTTAGCAGGCTC
CGAGCTTTCCTGGCATAGGTCAATCAGGTCCCAGGATGAATAATCCAGGCTTCAGCAACACTCCTCTTTCCCAGCCAGCAAAGGCTGTGA
ATTTGAATTCTTTGTTGGTATGTATGTGCAGGGAGTACTGTTAGGCACATTCTTAACCCATGTGGTTGGCCAGAAATCAGAAGTGGGGCT
GTGTCTCTGACTGGCTAGAGGCCAGGCCTTGTGGGTTTCTATCTGCTAAGCACCCAGCAGGTTGGGGCCTGGGACTCAGCTCTCTCTGCG
GTAGAGGCAGGCCCTCCTCCACTTCTTGGTACTAAACGAAGATCTCGACACCTTGCAGTTTTACTTCATTTCCTGCCCCTTTCAGGGCCT
GTGAGGATGCCCATGAGCTACCGCTGTACAGTTCTCGGCCCCGGCTTTCTTCCAAGAGTTGACCAGGAACCCTAAAGCATCCAGAGTAGA
CTGCGCTGCCACTGCGCACATGCTGGTGCCCGTCTTCCTCCTAAGGGGCCAGGCCACATCCAAGTGGGCCTCTGTCGGGGGCGGGGCGGT
AGGTCCGAAAGAAACCGCAGACACTACGATGCACTCCTCAAGCTGTCTTTTGTGCTTAGATCATCCATAGGTGTTTCTTCTGCTTGAAGC
TGCTATATCATCTTTATTTATTCAGGGTATTTTCATATTGGAAGCCTTGGCTAGTCTGCTCTAGCTCTGGGTTCTGTTTAGAGATTGGTT
TATTTCTGAATATTCAAGAAAGGAAAATGACTGGGCCTTTCTTTCTTTTCTTCTCCTCTGGGATGGGTAGTCTCCCTTTCCTAGAAAGGT
TATTATAACTTTAAGGACAGGCTTCAAGTGGGAAGGCCCCTACTTTTGCACTTCTCCAAGTGCAGGTCACACCAGGGGCAGACCCTGTCG
CTGCGTTTCTGAACTGTGAAGGAGCCCATTCGGGTGGGAGACTTCAGATGGGCTCAGTACCTGTCCCAGCCACAGGCTTCTTGTCCACCT
CTTCTCCCCTGCCCACCAGCTGCTCAGCGCATAAGACCTTCCCGACAGGCTCTGCGTGTGCAGCTCTCTGCGTCCCTCCTGGGCCCTCCA
GCGTCAGACACTAATGGGAGTTCCCGAGATGCTCGGGTTTGAGCAGGGAGCAGGCAGAGCTGCAGTCAGAGACATTAGAAAACCAGTCTG
AATTGGGTCTGTCTTTGAGATGCCCAGGCCAGCAGAAAGCAGCTCAGAAGTATTGTTGCTCATGGTGTGGCAATGGACTGAACTGTAATG
AAAATGTTATTTAATCTTTGTCTCTGTATTTTGATACTTGAATGACTTTCCCTTTTGTTTTACTGTATATAAAATTGTTAATCTGTCTGA
TTTTGTCTGAATTATAAACACTTTGAGGTACCAAACATAACCAATCTGTGCAACAACATAGACTGACCTCAGTACCCAAGAGAGTGTAAA
TATTTCTGGGCTTCCAGCTTTGGTTTTGTTATTTTCATAACTGTACACAACTTAGAACAGACTGAATTAATAAATGAGAAGCGACATGAA


>11904_11904_3_C6orf106-ANKS1A_C6orf106_chr6_34664223_ENST00000374023_ANKS1A_chr6_35021876_ENST00000360359_length(amino acids)=500AA_BP=36
MPGHHRQGRAHLRVPEAARLPAQSCRLRLLPGHDQLIEKIMSSIGEGIDFSQERQKISGLRTLEQSVGEWLESIGLQQYESKLLLNGFDD
VHFLGSNVMEEQDLRDIGISDPQHRRKLLQAARSLPKVKALGYDGNSPPSVPSWLDSLGLQDYVHSFLSSGYSSIDTVKNLWELELVNVL
KVQLLGHRKRIIASLADRPYEEPPQKPPRFSQLRCQDLLSQTSSPLSQNDSCTGRSADLLLPPGDTGRRRHDSLHDPAAPSRAERFRIQE
EHREAKLTLRPPSLAAPYAPVQSWQHQPEKLIFESCGYEANYLGSMLIKDLRGTESTQDACAKMRKSTEHMKKIPTIILSITYKGVKFID
ASNKNVIAEHEIRNISCAAQDPEDLCTFAYITKDLQTSHHYCHVFSTVDVNLTYEIILTLGQAFEVAYQLALQAQKSRATGASAAEMIET
KSSKPVPKPRVGVRKSALEPPDMDQDAQSHASVSWVVDPKPDSKRSLSTN

--------------------------------------------------------------
>11904_11904_4_C6orf106-ANKS1A_C6orf106_chr6_34664223_ENST00000374026_ANKS1A_chr6_35021876_ENST00000360359_length(transcript)=4602nt_BP=414nt
GGAGGCGGAGGCGGCGGAGTGGCGAGAGGCGAGAGGCGGCGGAGGCGGCGGAGCTGGGGGGGGTGGGAGGGGGGGGAGAGTGAGTGAGTG
GCAGAGTGAGTTTACCCCTATGAGACTGTGAGAGGCCCGGGGCCTACCTCAAAGGAGCGGGGTCGCGAAGCTAGCTAGCAGCGGCCCCCC
TCCAGGTCCCCGGGCCCGGCGGCGCGGCGGCGGCTTGGTTGTGAAGAGGCGGGGAAGCGGGTGTCCGGTCCCCGCCATGGAGGGCATGGA
CGTAGACCTGGACCCGGAGCTGATGCAGAAGTTCAGCTGCCTGGGCACCACCGACAAGGACGTGCTCATCTCCGAGTTCCAGAGGCTGCT
CGGCTTCCAGCTCAATCCTGCCGGTTGCGCCTTCTTCCTGGACATGACCAACTGATTGAGAAAATCATGAGTTCTATTGGAGAAGGGATT
GACTTTTCTCAGGAACGGCAGAAGATCTCAGGTTTACGGACGCTGGAGCAGAGTGTCGGGGAGTGGCTGGAGTCGATTGGGCTGCAGCAG
TATGAGAGCAAGTTGCTTCTGAATGGCTTTGACGATGTCCACTTCCTGGGGTCTAATGTGATGGAAGAGCAGGACCTGCGGGACATCGGC
ATCAGCGACCCACAGCACCGGCGGAAGCTGCTCCAGGCGGCACGCTCCCTACCCAAGGTGAAGGCTCTGGGTTATGACGGGAACAGCCCC
CCTAGCGTGCCCTCCTGGCTGGACTCCCTGGGGCTGCAGGACTACGTCCATTCCTTCTTGTCAAGTGGTTACAGCTCCATTGACACCGTG
AAGAACCTCTGGGAGCTAGAGCTCGTCAATGTCCTGAAGGTCCAGCTGCTCGGCCATCGCAAGCGCATCATCGCCTCCCTCGCAGACAGA
CCGTACGAGGAGCCGCCCCAGAAGCCCCCCAGATTCTCCCAGCTGAGGTGCCAAGATTTGCTCTCCCAGACGTCATCCCCACTGAGTCAG
AATGATTCCTGCACTGGGCGGTCGGCAGATCTGCTGCTGCCTCCAGGGGACACAGGCAGGAGGCGCCATGACAGTCTCCATGACCCTGCG
GCACCCTCCCGAGCGGAGCGCTTCAGGATCCAGGAGGAGCACCGTGAGGCCAAGCTGACCCTGCGGCCCCCGAGCCTGGCAGCCCCCTAC
GCCCCAGTGCAGAGTTGGCAACACCAGCCAGAGAAACTCATCTTCGAGTCCTGTGGTTATGAAGCCAATTATCTGGGCTCCATGCTGATC
AAAGATCTGCGAGGGACAGAATCCACGCAAGACGCCTGTGCCAAGATGCGGAAATCTACGGAGCACATGAAGAAGATCCCCACCATCATC
CTGTCCATCACATACAAAGGTGTCAAGTTCATCGATGCCTCCAACAAGAACGTCATTGCAGAGCACGAGATCCGGAACATTTCCTGTGCG
GCCCAGGACCCGGAGGACCTCTGTACCTTTGCCTACATCACCAAGGACCTGCAGACCAGCCACCACTATTGCCATGTGTTCAGCACCGTG
GATGTGAACCTGACCTACGAGATCATCCTGACGCTGGGGCAGGCCTTCGAAGTGGCCTATCAGTTGGCCCTGCAGGCCCAGAAGTCCAGG
GCGACGGGCGCCTCTGCAGCTGAGATGATTGAAACAAAATCTTCCAAACCGGTGCCTAAGCCTCGGGTCGGCGTGAGGAAATCCGCACTG
GAACCACCTGATATGGACCAAGATGCCCAATCCCATGCCAGTGTCTCCTGGGTTGTGGACCCCAAACCAGACTCTAAGCGGAGCCTCAGC
ACCAACTGAGCCACTGAGGAACCACACTGTGCTGCGGAAACATAGACGTGGGGGCATAGGCTCCCACTGCCACCACCGCCATCGCCTCAC
CTGCAGCTCTGAAGACCCAGGCCTCACCTCCGCCTGCAGGACCTCCTCTTGGCCACTTGGCCTGGGCCTGCCACCACCACGTCCTGCAGA
ACGAGCCCTGCCTTGGCTGTGGAGAAGCACTCCAGGCCGCTAGCAGATGGGACTGGCATTCCAGAGGGTCAAGAAGTGACTTGTTCAGAA
CACATTGTTTTTAACAGAAAAAAAATCTTTTTATAAAATGAACTTTTAACACTTGGCTCAAACCTCTAGGTCATACTGCCAATCTTTAGA
CAAATGGCCATGGGGCAGAGGACAGGGGAGCTGAGGTTGGTTCAGAGGCCAGCCTGCATAGCCTCTGTCCTCAGGACGGAACTTGGGTGC
AGCTCAGTGGGTCGGAAGAGAAGGCGGTGGCCTGTGGGTGAGGGGAACGGAGCAGGCTCAGGCAGAATTGAGTACGGTGCGTCTGCTTTT
CAAACCCAACCATATCAGCTGCTGCTCTTTATGAACTGCCCAACTTCCTGTCCCTTTCAGGGGCTAGACACAGGCTTCTCGTAAGAACAC
AGCCTTAGAGGCACCTGAGCAACTCAAAGGTTTCCGGTCCATTTCTGGGGTTCCCGATGGGAAGGTTCAGTGGCCAAATGAAGATAAGTG
TGCAGTTTCTAGTGCTGGGAAGTCTTAGCCAGCACCAGAGCGCCAGGCCTCTCCCTGGCCTCTTACCTGTCAGTGATCGGAGCACTGCCC
TGGGCTGGCCGGCGCCGTACTGCCTGCGTTGTGTCAGAGAATAGGAAAAGCAGCTTTGTTTGGGGCATTAATGCTTGGAGTGGGGTCAGC
TAAGGTTGCTACTTGCCAATTTGTGATTTGTCTAATCAGCCTGTGTGATTGGGGCTCATTTTGATTCTCTGAATTATCGGTTTGACGGTT
ACACTTGGCTGCTGGGCCCATCCCTGGCCCCCGGTGTGGAAAAGGCTAAATAAGGTGACAGTGCATCGATGCTCCCCCGCGTGGCCTTTG
GGGCAGGCTGGCATCCCGGTGCGCCTCTGCTTCTTAAGCTTTCCTGCTGCTCGCTTTGTTTTTAAAAGTAACTTGGGTTGCATTCTTCCC
TCTGGACTAGAGTAGAAATGCAGGGGAAACTGCTGTGGATTTGAGAGGCAAAGTTGGCTCAGCTGTGTGCCCAGTTCCTCCTGTGGGCAC
TTTAGCAGGCTCCGAGCTTTCCTGGCATAGGTCAATCAGGTCCCAGGATGAATAATCCAGGCTTCAGCAACACTCCTCTTTCCCAGCCAG
CAAAGGCTGTGAATTTGAATTCTTTGTTGGTATGTATGTGCAGGGAGTACTGTTAGGCACATTCTTAACCCATGTGGTTGGCCAGAAATC
AGAAGTGGGGCTGTGTCTCTGACTGGCTAGAGGCCAGGCCTTGTGGGTTTCTATCTGCTAAGCACCCAGCAGGTTGGGGCCTGGGACTCA
GCTCTCTCTGCGGTAGAGGCAGGCCCTCCTCCACTTCTTGGTACTAAACGAAGATCTCGACACCTTGCAGTTTTACTTCATTTCCTGCCC
CTTTCAGGGCCTGTGAGGATGCCCATGAGCTACCGCTGTACAGTTCTCGGCCCCGGCTTTCTTCCAAGAGTTGACCAGGAACCCTAAAGC
ATCCAGAGTAGACTGCGCTGCCACTGCGCACATGCTGGTGCCCGTCTTCCTCCTAAGGGGCCAGGCCACATCCAAGTGGGCCTCTGTCGG
GGGCGGGGCGGTAGGTCCGAAAGAAACCGCAGACACTACGATGCACTCCTCAAGCTGTCTTTTGTGCTTAGATCATCCATAGGTGTTTCT
TCTGCTTGAAGCTGCTATATCATCTTTATTTATTCAGGGTATTTTCATATTGGAAGCCTTGGCTAGTCTGCTCTAGCTCTGGGTTCTGTT
TAGAGATTGGTTTATTTCTGAATATTCAAGAAAGGAAAATGACTGGGCCTTTCTTTCTTTTCTTCTCCTCTGGGATGGGTAGTCTCCCTT
TCCTAGAAAGGTTATTATAACTTTAAGGACAGGCTTCAAGTGGGAAGGCCCCTACTTTTGCACTTCTCCAAGTGCAGGTCACACCAGGGG
CAGACCCTGTCGCTGCGTTTCTGAACTGTGAAGGAGCCCATTCGGGTGGGAGACTTCAGATGGGCTCAGTACCTGTCCCAGCCACAGGCT
TCTTGTCCACCTCTTCTCCCCTGCCCACCAGCTGCTCAGCGCATAAGACCTTCCCGACAGGCTCTGCGTGTGCAGCTCTCTGCGTCCCTC
CTGGGCCCTCCAGCGTCAGACACTAATGGGAGTTCCCGAGATGCTCGGGTTTGAGCAGGGAGCAGGCAGAGCTGCAGTCAGAGACATTAG
AAAACCAGTCTGAATTGGGTCTGTCTTTGAGATGCCCAGGCCAGCAGAAAGCAGCTCAGAAGTATTGTTGCTCATGGTGTGGCAATGGAC
TGAACTGTAATGAAAATGTTATTTAATCTTTGTCTCTGTATTTTGATACTTGAATGACTTTCCCTTTTGTTTTACTGTATATAAAATTGT
TAATCTGTCTGATTTTGTCTGAATTATAAACACTTTGAGGTACCAAACATAACCAATCTGTGCAACAACATAGACTGACCTCAGTACCCA
AGAGAGTGTAAATATTTCTGGGCTTCCAGCTTTGGTTTTGTTATTTTCATAACTGTACACAACTTAGAACAGACTGAATTAATAAATGAG
AAGCGACATGAA

>11904_11904_4_C6orf106-ANKS1A_C6orf106_chr6_34664223_ENST00000374026_ANKS1A_chr6_35021876_ENST00000360359_length(amino acids)=500AA_BP=36
MPGHHRQGRAHLRVPEAARLPAQSCRLRLLPGHDQLIEKIMSSIGEGIDFSQERQKISGLRTLEQSVGEWLESIGLQQYESKLLLNGFDD
VHFLGSNVMEEQDLRDIGISDPQHRRKLLQAARSLPKVKALGYDGNSPPSVPSWLDSLGLQDYVHSFLSSGYSSIDTVKNLWELELVNVL
KVQLLGHRKRIIASLADRPYEEPPQKPPRFSQLRCQDLLSQTSSPLSQNDSCTGRSADLLLPPGDTGRRRHDSLHDPAAPSRAERFRIQE
EHREAKLTLRPPSLAAPYAPVQSWQHQPEKLIFESCGYEANYLGSMLIKDLRGTESTQDACAKMRKSTEHMKKIPTIILSITYKGVKFID
ASNKNVIAEHEIRNISCAAQDPEDLCTFAYITKDLQTSHHYCHVFSTVDVNLTYEIILTLGQAFEVAYQLALQAQKSRATGASAAEMIET
KSSKPVPKPRVGVRKSALEPPDMDQDAQSHASVSWVVDPKPDSKRSLSTN

--------------------------------------------------------------

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Fusion Gene PPI Analysis for C6orf106-ANKS1A


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for C6orf106-ANKS1A


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for C6orf106-ANKS1A


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneC0010054Coronary Arteriosclerosis1CTD_human
TgeneC1956346Coronary Artery Disease1CTD_human