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in Kim Lab

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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:CRTC3-MAML2 (FusionGDB2 ID:HG64784TG84441)

Fusion Gene Summary for CRTC3-MAML2

check button Fusion gene summary
Fusion gene informationFusion gene name: CRTC3-MAML2
Fusion gene ID: hg64784tg84441
HgeneTgene
Gene symbol

CRTC3

MAML2

Gene ID

64784

84441

Gene nameCREB regulated transcription coactivator 3mastermind like transcriptional coactivator 2
SynonymsTORC-3|TORC3MAM-3|MAM2|MAM3|MLL-MAML2
Cytomap('CRTC3')('MAML2')

15q26.1

11q21

Type of geneprotein-codingprotein-coding
DescriptionCREB-regulated transcription coactivator 3transducer of regulated CREB protein 3transducer of regulated cAMP response element-binding protein (CREB) 3mastermind-like protein 2mam-2mastermind-like 2
Modification date2020031320200313
UniProtAcc

Q6UUV7

Q8IZL2

Ensembl transtripts involved in fusion geneENST00000268184, ENST00000420329, 
ENST00000560098, ENST00000558619, 
Fusion gene scores* DoF score7 X 6 X 7=29414 X 24 X 9=3024
# samples 921
** MAII scorelog2(9/294*10)=-1.70781924850669
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(21/3024*10)=-3.84799690655495
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CRTC3 [Title/Abstract] AND MAML2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCRTC3(91073435)-MAML2(95826625), # samples:1
CRTC3(91073435)-MAML2(95826682), # samples:1
Anticipated loss of major functional domain due to fusion event.CRTC3-MAML2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
CRTC3-MAML2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneMAML2

GO:0007219

Notch signaling pathway

12370315

TgeneMAML2

GO:0045944

positive regulation of transcription by RNA polymerase II

12370315


check buttonFusion gene breakpoints across CRTC3 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across MAML2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4mucoepidermoid carcinomaEU048224CRTC3chr15

91073435

MAML2chr11

95826625
ChimerKB3..CRTC3chr15

91073435

+MAML2chr11

95711919

-
ChimerKB3..CRTC3chr15

91073435

+MAML2chr11

95826681

-


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Fusion Gene ORF analysis for CRTC3-MAML2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000268184ENST00000524717CRTC3chr15

91073435

+MAML2chr11

95711919

-
5CDS-3UTRENST00000420329ENST00000524717CRTC3chr15

91073435

+MAML2chr11

95711919

-
5CDS-3UTRENST00000560098ENST00000524717CRTC3chr15

91073435

+MAML2chr11

95711919

-
In-frameENST00000268184ENST00000524717CRTC3chr15

91073435

MAML2chr11

95826625

In-frameENST00000268184ENST00000524717CRTC3chr15

91073435

+MAML2chr11

95826681

-
In-frameENST00000420329ENST00000524717CRTC3chr15

91073435

MAML2chr11

95826625

In-frameENST00000420329ENST00000524717CRTC3chr15

91073435

+MAML2chr11

95826681

-
In-frameENST00000560098ENST00000524717CRTC3chr15

91073435

MAML2chr11

95826625

In-frameENST00000560098ENST00000524717CRTC3chr15

91073435

+MAML2chr11

95826681

-
intron-3CDSENST00000558619ENST00000524717CRTC3chr15

91073435

MAML2chr11

95826625

intron-3CDSENST00000558619ENST00000524717CRTC3chr15

91073435

+MAML2chr11

95826681

-
intron-3UTRENST00000558619ENST00000524717CRTC3chr15

91073435

+MAML2chr11

95711919

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000420329CRTC3chr1591073435+ENST00000524717MAML2chr1195826681-558727914732361029
ENST00000560098CRTC3chr1591073435+ENST00000524717MAML2chr1195826681-554423610431931029
ENST00000268184CRTC3chr1591073435+ENST00000524717MAML2chr1195826681-5444136430931029
ENST00000420329CRTC3chr1591073435ENST00000524717MAML2chr1195826625553127939535530526
ENST00000560098CRTC3chr1591073435ENST00000524717MAML2chr1195826625548823639105487526
ENST00000268184CRTC3chr1591073435ENST00000524717MAML2chr1195826625538813638105387526

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000420329ENST00000524717CRTC3chr1591073435+MAML2chr1195826682-0.0007711490.99922884
ENST00000560098ENST00000524717CRTC3chr1591073435+MAML2chr1195826682-0.0007233530.9992767
ENST00000268184ENST00000524717CRTC3chr1591073435+MAML2chr1195826682-0.0006891510.99931085
ENST00000420329ENST00000524717CRTC3chr1591073435MAML2chr11958266250.0055619890.99443805
ENST00000560098ENST00000524717CRTC3chr1591073435MAML2chr11958266250.0058485630.9941514
ENST00000268184ENST00000524717CRTC3chr1591073435MAML2chr11958266250.0058388640.99416107

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Fusion Genomic Features for CRTC3-MAML2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for CRTC3-MAML2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr15:91073435/chr11:95826625)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
CRTC3

Q6UUV7

MAML2

Q8IZL2

FUNCTION: Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR). {ECO:0000269|PubMed:14506290, ECO:0000269|PubMed:15454081, ECO:0000269|PubMed:15466468, ECO:0000269|PubMed:16817901, ECO:0000269|PubMed:16980408, ECO:0000269|PubMed:17210223, ECO:0000269|PubMed:17644518}.FUNCTION: Acts as a transcriptional coactivator for NOTCH proteins. Has been shown to amplify NOTCH-induced transcription of HES1. Potentiates activation by NOTCH3 and NOTCH4 more efficiently than MAML1 or MAML3. {ECO:0000269|PubMed:12370315, ECO:0000269|PubMed:12386158, ECO:0000269|PubMed:12539049}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCRTC3chr15:91073435chr11:95826682ENST00000268184+115180_18344620.0Compositional biasNote=Poly-Gly
HgeneCRTC3chr15:91073435chr11:95826682ENST00000268184+115444_45144620.0Compositional biasNote=Poly-Pro
HgeneCRTC3chr15:91073435chr11:95826682ENST00000420329+115180_18344619.0Compositional biasNote=Poly-Gly
HgeneCRTC3chr15:91073435chr11:95826682ENST00000420329+115444_45144619.0Compositional biasNote=Poly-Pro


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Fusion Gene Sequence for CRTC3-MAML2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>19573_19573_1_CRTC3-MAML2_CRTC3_chr15_91073435_ENST00000268184_MAML2_chr11_95826625_ENST00000524717_length(transcript)=5388nt_BP=136nt
CGCCATGGCCGCCTCGCCGGGCTCGGGCAGCGCCAACCCGCGGAAGTTCAGTGAGAAGATCGCGCTGCACACGCAGAGACAGGCCGAGGA
GACGCGGGCCTTCGAGCAGCTCATGACCGACCTCACCCTGTCGCGGGTGGCTCATCCACAATAAGCTTAAACTCTAACCAGGCTTTGGCA
AACCCAGTTTCAACACACACCATTTTAACTCCCAATTCCAGCCTCCTGTCTACTTCTCACGGGACAAGAATGCCATCATTATCTACAGCA
GTTCAGAATATGGGGATGTATGGAAATCTGCCTTGTAATCAACCTAACACATACAGTGTCACTTCAGGAATGAATCAATTGACCCAACAG
AGAAACCCAAAGCAATTGTTAGCAAATCAAAACAACCCTATGATGCCACGGCCACCTACCTTAGGGCCAAGTAATAATAACAATGTAGCC
ACTTTTGGAGCTGGATCTGTTGGTAATTCACAACAATTGAGACCAAATTTAACCCATAGTATGGCAAGCATGCCACCACAGAGAACATCA
AACGTAATGATCACATCCAACACAACTGCACCAAACTGGGCCTCTCAAGAAGGAACAAGCAAACAGCAAGAAGCCCTGACGTCTGCAGGA
GTCCGCTTCCCCACAGGTACACCTGCAGCCTATACCCCAAATCAGTCACTGCAACAGGCAGTAGGTAGCCAGCAATTTTCCCAGAGGGCA
GTGGCTCCTCCTAACCAGTTAACACCAGCAGTGCAAATGAGACCCATGAACCAAATGAGCCAAACACTAAATGGGCAAACCATGGGTCCC
CTCAGGGGTCTGAATCTCAGACCCAATCAGCTAAGCACACAGATTTTGCCTAATTTGAATCAGTCAGGAACAGGGTTGAATCAGTCGAGG
ACGGGCATCAACCAGCCACCATCCCTGACGCCCAGCAATTTTCCTTCACCCAACCAAAGTTCCAGGGCTTTTCAAGGAACTGACCACAGC
AGTGACTTAGCTTTTGACTTCCTCAGCCAACAAAATGATAACATGGGCCCTGCCCTAAACAGTGATGCTGATTTCATTGATTCTTTATTG
AAGACAGAGCCTGGTAATGATGACTGGATGAAAGACATCAATCTTGATGAAATCTTGGGGAACAATTCCTAAAGAAGAAAGGGAAGACAA
TTTACAAACTCCAAGCACTAAAAGGCAGTATATTACAGAAACTCTGTAGAGGCTGAACTGTTGATGTTCAGGTGGACTACATGAAGATAA
CATGCTTAAAAATGGAAAGCAGAAAGTAACTGCAGTGATGAACATTTTGGTCCAAATTCTTGTTTTAAATCTTACACCTGAAAGTAAAAT
ATTGGGATCACTTTTCCCTGTCTAAACTCCAGGATACAGTATCCAATTTATCCAAACAGAACTGTGGTGTCAATGTGTAATTAATTGTGT
AAAATAGCCTTCCCAAGTTTCTTTTTCCCTGGAAAATAAAAAAGGTAATAGAACTTGTAGTTTATTTAAACCCCATGTCATGAGGAGGTA
CTAGTTCCAAGCAACAAACTCCTTAATTTGCTCTAATAGATAGGTATGGTTTAATCTTTCCATTGTGTCTTTTCATTTAATTTTCCTGAA
GCTTGCAGGATAGATTGAAATGTTATAGGTTTGTTTGGAGTAACCAAACAGTATGCAAATTAAGAAAAAGCCAGAGAACCTAGAAAACAT
CCAGTGGATTACAGAATTTCTTCCCCATATTCACTCCTCACTTTTACAATTTTCCCACAATCCTCTACTTCAGTGGGATGCTGTGTCTAG
TGATTAAACAAAAATATAGAGCTGTGCAATTTGATTTTGGCTTCCACAACGAATATCTGAATCCATTCCAAATGAAATTTTAGATATAAC
AAAGACTTGTCCTAATCATACTGAAATATTGGTGCACACCTCTCTGCATTAGATTTCACTTTTTTAAAAAACCCAGTGGACATTGCTATA
AATAAGATTTATTTGGCTACAAATAACCTGGGATGTTGCTTATTATGATTGATGCCTGCTGGTTTGTTCCCAAGCTGAGTGAAATTGAAC
CTCGTCCTCCCTACTCATTTTGATGACTGAGGCTGGTTTATAAGAAAAGGAAGTTTGGAGAAGAAAACCGAGATTAGAAAATATCATGTT
TTGGTTGGAGATAAGAACCAGGGATGGCAAGTACCAGTGTGTACAAATGTATTTCACGGAGTTTGAAGGAACGCATAATCAAGAGGGAAA
ACAATTTGTCCTTCATTGGACGTATTATTTGGATTTGGGTGAGCAACAAAATGGAATGTGGTCTGTTAGGAGCATTCTGTTTGTTCTTTT
GTCCCTGATGTGATGAATCATTGCCACATGCTAGATGGACTCTTCATATCCAGGTTTTGTCCCTCAGGGCTGAGCACTGTATTAAAGAGT
TTTTGTTGAGTCATTTAACCTTAGTGTCCACATCCAGATCAGCTGTAAAATGGGGAAGACGTGTGCTGATTTGGAATGAATGCAAAATAT
CACTATCATTTTCCTAATTACAGAGGAGCAAAGGTTATCTTCAGCCCTTTCAGTTCTATGCTCACATATTCAAATATCAAATGTAATTTA
GCTGAAGTTATTTAATAATCAAGTCTTTCAATATCTGTTCAAAGAAAAAGAACACACTTTGAAAATTCTGCAAAGCTGTCTCCCAGTCTT
TAAAATGTCTGGAAGCACTCTCCTTCTTTACAATACCAACATCACTGGCCCAGAATCTTCCCTGTGCTAGTTTGTAAATATAAATAAATT
ACTTGTTTTGTAAACTTTTGTAAAGAATATTTTGGTAGAAATACTTCAAACATATTCTTTGGGTTATATTTATACATATGTGAAATAAAT
ATACTATCAAAAGGTTATATTTTATACAAAAAGTAAATTGCTACCTTTTGTATGCTAATATGCAAAGTTTTGTATAATATGATGGTTTAT
TTTTAGCTCTACACTTAAACCATAGGTGGTTGAGTGGGAACTTTTGAAAACTATCAAGAGGCTTGTTAGACAAATTTATATTCTGAAACC
TCAATAAGAAAGCATTCCAGGTTTCAATCCTTGTTTTTTGTCCTGCTCCCAAATTCTTTTTTAAACCCATAGTTCTTGTGTCTTATTTGA
TTCTTCTGCTGTGCACATTGTATTGGTCCTTGTTGCATGTAGTCTACTGTGTGTTTTCCGATTTTATAAGGCAGCATTTCTCCATACAAA
AAGAAAAAAAATGATGTACATATAAACGCTTTTGTTGTATGGCTCCTCCATGTTACTGTATATATCTGCCAGCACTTCCCAGTTACACTC
CTGTGAGTCAGCTTATTTTTACCCTAACATAAATAGTATGTTTTGTAGTAGTTATCAAATTTAAGAGATAAAGCAATCAGAATGTTTGGA
TTTTCTTCTATCTTAATGTGAATTTCATAATTAATGTCTATTTATTCAGCTATTCATTAAAATACAGGATTCTTTGGGAAAAGAGAAAAT
TGCTCCACAAGATCAGATAAACCGACATTTGTCAAGGCCACCTCCAGATTATAAAGACCAAAGAAGAAATGTGGGCAATATGCAACCAAC
TGCTCAGTATTCTGGATCAACACTCTGTGGTAGGCCAGAACACAGGCCCCAGTCCAAGTCCTAACCCCTGCTCAAATCCAAACACTGGAA
GTGGTTACATGAACTCCCAGCAATCACTGTTGAATCAGCAATTGATGGGAAAGAAGCAGACTCTACAGAGGCAGATCATGGAGCAGAAAC
AGCAACTTCTTCTCCAGCAGCAGATGCTGGCTGACGCGGCGACCCAATGGCTTTGTGGACAACTCATTTCTTGATATCAAAAGAATTCGT
GTTGGGGAGAATCTCTCTGCAGGACAAGGTGGCCTCCAAATAAACAATGGACAAAGTCAGATTATGTCAGGGACCTTGCCTATGAGCCAA
GCACCCCTGCGAAAGACTAACACTCTGCCATCCCATACACATTCTCCTGGCAATGGCCTGTTTAACATGGGCTTAAAGGAGGTAAAGAAG
GAGCCAGGAGAGACTCTGTCTTGCAGTAAGCACATGGATGGCCAAATGACCCAAGAGAATATTTTTCCTAATAGGTACGGAGACGACCCT
GGAGAACAACTGATGGATCCTGAGCTGCAGGAACTGTTCAATGAACTGACCAACATATCTGTGCCTCCCATGAGTGACCTTGAACTGGAG
AACATGATCAATGCCACCATAAAGCAGGATGACCCATTTAACATTGACTTGGGTCAGCAAAGCCAGAGGAGCACACCTAGGCCCTCCTTA
CCCATGGAGAAAATAGTGATCAAAAGTGAATACTCACCGGGCTTGACTCAGGGCCCCTCAGGCTCTCCTCAGCTGAGGCCCCCATCAGCT
GGCCCCGCATTCTCCATGGCCAACTCTGCCCTCTCCACTTCGTCTCCAATCCCTTCAGTCCCTCAGAGCCAGGCTCAGCCTCAGACAGGC
TCCGGAGCAAGCCGGGCCTTGCCAAGCTGGCAGGAAGTATCCCATGCCCAGCAGCTCAAACAGATAGCTGCTAATCGTCAGCAGCATGCC
CGGATGCAGCAGCACCAGCAGCAGCACCAGCCTACCAACTGGTCAGCCTTGCCCTCTTCTGCTGGACCATCACCAGGTCCATTTGGGCAG
GAGAAAATCCCCAGCCCTTCTTTTGGTCAGCAGACATTCAGCCCACAGAGCTCCCCCATGCCTGGGGTAGCTGGCGGCAGCGGCCAGTCG
AAAGTAATGGCTAACTACATGTACAAGGCCGGCCCCTCAGCCCAGGGTGGGCACCTAGATGTCCTCATGCAGCAAAAGCCTCAGGATCTC
AGTCGAAGTTTTATTAACAACCCGCACCCAGCCATGGAGCCCCGTCAGGGCAACACCAAGCCTTTGTTTCATTTTAACTCAGATCAAGCG
AACCAGCAGATGCCTTCTGTTTTGCCTTCCCAGAACAAGCCTTCTCTCCTACACTACACCCAACAGCAACAGCAGCAACAGCAGCAGCAG
CAGCAGCAGCAGCAGCAGCAGCAGCAGCAACAGCAGCAGCAGCAGCAACAGCAACAGCAACAGCAACAGCAGAGTTCAATTTCAGCTCAA
CAACAGCAACAGCAGCAGAGCTCAATTTCAGCCCAACAGCAGCAGCAGCAGCAACAACAGCAGCAGCAGCAGCAACAACAACAGCAACAA
CAGCAGCAGCAGCAGCAGCAACAACCATCTTCTCAGCCTGCCCAATCTCTACCAAGCCAGCCTTTGCTAAGGTCACCTTTGCCACTTCAG
CAAAAGCTCCTACTTCAGCAAATGCAGAATCAGCCCATTGCAGGAATGGGATACCAAGTCTCCCAACAACAGAGACAG

>19573_19573_1_CRTC3-MAML2_CRTC3_chr15_91073435_ENST00000268184_MAML2_chr11_95826625_ENST00000524717_length(amino acids)=526AA_BP=3
MTRRPNGFVDNSFLDIKRIRVGENLSAGQGGLQINNGQSQIMSGTLPMSQAPLRKTNTLPSHTHSPGNGLFNMGLKEVKKEPGETLSCSK
HMDGQMTQENIFPNRYGDDPGEQLMDPELQELFNELTNISVPPMSDLELENMINATIKQDDPFNIDLGQQSQRSTPRPSLPMEKIVIKSE
YSPGLTQGPSGSPQLRPPSAGPAFSMANSALSTSSPIPSVPQSQAQPQTGSGASRALPSWQEVSHAQQLKQIAANRQQHARMQQHQQQHQ
PTNWSALPSSAGPSPGPFGQEKIPSPSFGQQTFSPQSSPMPGVAGGSGQSKVMANYMYKAGPSAQGGHLDVLMQQKPQDLSRSFINNPHP
AMEPRQGNTKPLFHFNSDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSIS
AQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLLQQMQNQPIAGMGYQVSQQQRQ

--------------------------------------------------------------
>19573_19573_2_CRTC3-MAML2_CRTC3_chr15_91073435_ENST00000268184_MAML2_chr11_95826681_ENST00000524717_length(transcript)=5444nt_BP=136nt
CGCCATGGCCGCCTCGCCGGGCTCGGGCAGCGCCAACCCGCGGAAGTTCAGTGAGAAGATCGCGCTGCACACGCAGAGACAGGCCGAGGA
GACGCGGGCCTTCGAGCAGCTCATGACCGACCTCACCCTGTCGCGGCTCCAGGGTTCCTTGAAAAGAAAACAGGTAGTTAACCTATCTCC
TGCCAACAGCAAGCGACCCAATGGCTTTGTGGACAACTCATTTCTTGATATCAAAAGAATTCGTGTTGGGGAGAATCTCTCTGCAGGACA
AGGTGGCCTCCAAATAAACAATGGACAAAGTCAGATTATGTCAGGGACCTTGCCTATGAGCCAAGCACCCCTGCGAAAGACTAACACTCT
GCCATCCCATACACATTCTCCTGGCAATGGCCTGTTTAACATGGGCTTAAAGGAGGTAAAGAAGGAGCCAGGAGAGACTCTGTCTTGCAG
TAAGCACATGGATGGCCAAATGACCCAAGAGAATATTTTTCCTAATAGGTACGGAGACGACCCTGGAGAACAACTGATGGATCCTGAGCT
GCAGGAACTGTTCAATGAACTGACCAACATATCTGTGCCTCCCATGAGTGACCTTGAACTGGAGAACATGATCAATGCCACCATAAAGCA
GGATGACCCATTTAACATTGACTTGGGTCAGCAAAGCCAGAGGAGCACACCTAGGCCCTCCTTACCCATGGAGAAAATAGTGATCAAAAG
TGAATACTCACCGGGCTTGACTCAGGGCCCCTCAGGCTCTCCTCAGCTGAGGCCCCCATCAGCTGGCCCCGCATTCTCCATGGCCAACTC
TGCCCTCTCCACTTCGTCTCCAATCCCTTCAGTCCCTCAGAGCCAGGCTCAGCCTCAGACAGGCTCCGGAGCAAGCCGGGCCTTGCCAAG
CTGGCAGGAAGTATCCCATGCCCAGCAGCTCAAACAGATAGCTGCTAATCGTCAGCAGCATGCCCGGATGCAGCAGCACCAGCAGCAGCA
CCAGCCTACCAACTGGTCAGCCTTGCCCTCTTCTGCTGGACCATCACCAGGTCCATTTGGGCAGGAGAAAATCCCCAGCCCTTCTTTTGG
TCAGCAGACATTCAGCCCACAGAGCTCCCCCATGCCTGGGGTAGCTGGCGGCAGCGGCCAGTCGAAAGTAATGGCTAACTACATGTACAA
GGCCGGCCCCTCAGCCCAGGGTGGGCACCTAGATGTCCTCATGCAGCAAAAGCCTCAGGATCTCAGTCGAAGTTTTATTAACAACCCGCA
CCCAGCCATGGAGCCCCGTCAGGGCAACACCAAGCCTTTGTTTCATTTTAACTCAGATCAAGCGAACCAGCAGATGCCTTCTGTTTTGCC
TTCCCAGAACAAGCCTTCTCTCCTACACTACACCCAACAGCAACAGCAGCAACAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCA
GCAACAGCAGCAGCAGCAGCAACAGCAACAGCAACAGCAACAGCAGAGTTCAATTTCAGCTCAACAACAGCAACAGCAGCAGAGCTCAAT
TTCAGCCCAACAGCAGCAGCAGCAGCAACAACAGCAGCAGCAGCAGCAACAACAACAGCAACAACAGCAGCAGCAGCAGCAGCAACAACC
ATCTTCTCAGCCTGCCCAATCTCTACCAAGCCAGCCTTTGCTAAGGTCACCTTTGCCACTTCAGCAAAAGCTCCTACTTCAGCAAATGCA
GAATCAGCCCATTGCAGGAATGGGATACCAAGTCTCCCAACAACAGAGACAGGATCAACACTCTGTGGTAGGCCAGAACACAGGCCCCAG
TCCAAGTCCTAACCCCTGCTCAAATCCAAACACTGGAAGTGGTTACATGAACTCCCAGCAATCACTGTTGAATCAGCAATTGATGGGAAA
GAAGCAGACTCTACAGAGGCAGATCATGGAGCAGAAACAGCAACTTCTTCTCCAGCAGCAGATGCTGGCTGACGCGGAGAAAATTGCTCC
ACAAGATCAGATAAACCGACATTTGTCAAGGCCACCTCCAGATTATAAAGACCAAAGAAGAAATGTGGGCAATATGCAACCAACTGCTCA
GTATTCTGGTGGCTCATCCACAATAAGCTTAAACTCTAACCAGGCTTTGGCAAACCCAGTTTCAACACACACCATTTTAACTCCCAATTC
CAGCCTCCTGTCTACTTCTCACGGGACAAGAATGCCATCATTATCTACAGCAGTTCAGAATATGGGGATGTATGGAAATCTGCCTTGTAA
TCAACCTAACACATACAGTGTCACTTCAGGAATGAATCAATTGACCCAACAGAGAAACCCAAAGCAATTGTTAGCAAATCAAAACAACCC
TATGATGCCACGGCCACCTACCTTAGGGCCAAGTAATAATAACAATGTAGCCACTTTTGGAGCTGGATCTGTTGGTAATTCACAACAATT
GAGACCAAATTTAACCCATAGTATGGCAAGCATGCCACCACAGAGAACATCAAACGTAATGATCACATCCAACACAACTGCACCAAACTG
GGCCTCTCAAGAAGGAACAAGCAAACAGCAAGAAGCCCTGACGTCTGCAGGAGTCCGCTTCCCCACAGGTACACCTGCAGCCTATACCCC
AAATCAGTCACTGCAACAGGCAGTAGGTAGCCAGCAATTTTCCCAGAGGGCAGTGGCTCCTCCTAACCAGTTAACACCAGCAGTGCAAAT
GAGACCCATGAACCAAATGAGCCAAACACTAAATGGGCAAACCATGGGTCCCCTCAGGGGTCTGAATCTCAGACCCAATCAGCTAAGCAC
ACAGATTTTGCCTAATTTGAATCAGTCAGGAACAGGGTTGAATCAGTCGAGGACGGGCATCAACCAGCCACCATCCCTGACGCCCAGCAA
TTTTCCTTCACCCAACCAAAGTTCCAGGGCTTTTCAAGGAACTGACCACAGCAGTGACTTAGCTTTTGACTTCCTCAGCCAACAAAATGA
TAACATGGGCCCTGCCCTAAACAGTGATGCTGATTTCATTGATTCTTTATTGAAGACAGAGCCTGGTAATGATGACTGGATGAAAGACAT
CAATCTTGATGAAATCTTGGGGAACAATTCCTAAAGAAGAAAGGGAAGACAATTTACAAACTCCAAGCACTAAAAGGCAGTATATTACAG
AAACTCTGTAGAGGCTGAACTGTTGATGTTCAGGTGGACTACATGAAGATAACATGCTTAAAAATGGAAAGCAGAAAGTAACTGCAGTGA
TGAACATTTTGGTCCAAATTCTTGTTTTAAATCTTACACCTGAAAGTAAAATATTGGGATCACTTTTCCCTGTCTAAACTCCAGGATACA
GTATCCAATTTATCCAAACAGAACTGTGGTGTCAATGTGTAATTAATTGTGTAAAATAGCCTTCCCAAGTTTCTTTTTCCCTGGAAAATA
AAAAAGGTAATAGAACTTGTAGTTTATTTAAACCCCATGTCATGAGGAGGTACTAGTTCCAAGCAACAAACTCCTTAATTTGCTCTAATA
GATAGGTATGGTTTAATCTTTCCATTGTGTCTTTTCATTTAATTTTCCTGAAGCTTGCAGGATAGATTGAAATGTTATAGGTTTGTTTGG
AGTAACCAAACAGTATGCAAATTAAGAAAAAGCCAGAGAACCTAGAAAACATCCAGTGGATTACAGAATTTCTTCCCCATATTCACTCCT
CACTTTTACAATTTTCCCACAATCCTCTACTTCAGTGGGATGCTGTGTCTAGTGATTAAACAAAAATATAGAGCTGTGCAATTTGATTTT
GGCTTCCACAACGAATATCTGAATCCATTCCAAATGAAATTTTAGATATAACAAAGACTTGTCCTAATCATACTGAAATATTGGTGCACA
CCTCTCTGCATTAGATTTCACTTTTTTAAAAAACCCAGTGGACATTGCTATAAATAAGATTTATTTGGCTACAAATAACCTGGGATGTTG
CTTATTATGATTGATGCCTGCTGGTTTGTTCCCAAGCTGAGTGAAATTGAACCTCGTCCTCCCTACTCATTTTGATGACTGAGGCTGGTT
TATAAGAAAAGGAAGTTTGGAGAAGAAAACCGAGATTAGAAAATATCATGTTTTGGTTGGAGATAAGAACCAGGGATGGCAAGTACCAGT
GTGTACAAATGTATTTCACGGAGTTTGAAGGAACGCATAATCAAGAGGGAAAACAATTTGTCCTTCATTGGACGTATTATTTGGATTTGG
GTGAGCAACAAAATGGAATGTGGTCTGTTAGGAGCATTCTGTTTGTTCTTTTGTCCCTGATGTGATGAATCATTGCCACATGCTAGATGG
ACTCTTCATATCCAGGTTTTGTCCCTCAGGGCTGAGCACTGTATTAAAGAGTTTTTGTTGAGTCATTTAACCTTAGTGTCCACATCCAGA
TCAGCTGTAAAATGGGGAAGACGTGTGCTGATTTGGAATGAATGCAAAATATCACTATCATTTTCCTAATTACAGAGGAGCAAAGGTTAT
CTTCAGCCCTTTCAGTTCTATGCTCACATATTCAAATATCAAATGTAATTTAGCTGAAGTTATTTAATAATCAAGTCTTTCAATATCTGT
TCAAAGAAAAAGAACACACTTTGAAAATTCTGCAAAGCTGTCTCCCAGTCTTTAAAATGTCTGGAAGCACTCTCCTTCTTTACAATACCA
ACATCACTGGCCCAGAATCTTCCCTGTGCTAGTTTGTAAATATAAATAAATTACTTGTTTTGTAAACTTTTGTAAAGAATATTTTGGTAG
AAATACTTCAAACATATTCTTTGGGTTATATTTATACATATGTGAAATAAATATACTATCAAAAGGTTATATTTTATACAAAAAGTAAAT
TGCTACCTTTTGTATGCTAATATGCAAAGTTTTGTATAATATGATGGTTTATTTTTAGCTCTACACTTAAACCATAGGTGGTTGAGTGGG
AACTTTTGAAAACTATCAAGAGGCTTGTTAGACAAATTTATATTCTGAAACCTCAATAAGAAAGCATTCCAGGTTTCAATCCTTGTTTTT
TGTCCTGCTCCCAAATTCTTTTTTAAACCCATAGTTCTTGTGTCTTATTTGATTCTTCTGCTGTGCACATTGTATTGGTCCTTGTTGCAT
GTAGTCTACTGTGTGTTTTCCGATTTTATAAGGCAGCATTTCTCCATACAAAAAGAAAAAAAATGATGTACATATAAACGCTTTTGTTGT
ATGGCTCCTCCATGTTACTGTATATATCTGCCAGCACTTCCCAGTTACACTCCTGTGAGTCAGCTTATTTTTACCCTAACATAAATAGTA
TGTTTTGTAGTAGTTATCAAATTTAAGAGATAAAGCAATCAGAATGTTTGGATTTTCTTCTATCTTAATGTGAATTTCATAATTAATGTC
TATTTATTCAGCTATTCATTAAAATACAGGATTCTTTGGGAAAA

>19573_19573_2_CRTC3-MAML2_CRTC3_chr15_91073435_ENST00000268184_MAML2_chr11_95826681_ENST00000524717_length(amino acids)=1029AA_BP=44
MAASPGSGSANPRKFSEKIALHTQRQAEETRAFEQLMTDLTLSRLQGSLKRKQVVNLSPANSKRPNGFVDNSFLDIKRIRVGENLSAGQG
GLQINNGQSQIMSGTLPMSQAPLRKTNTLPSHTHSPGNGLFNMGLKEVKKEPGETLSCSKHMDGQMTQENIFPNRYGDDPGEQLMDPELQ
ELFNELTNISVPPMSDLELENMINATIKQDDPFNIDLGQQSQRSTPRPSLPMEKIVIKSEYSPGLTQGPSGSPQLRPPSAGPAFSMANSA
LSTSSPIPSVPQSQAQPQTGSGASRALPSWQEVSHAQQLKQIAANRQQHARMQQHQQQHQPTNWSALPSSAGPSPGPFGQEKIPSPSFGQ
QTFSPQSSPMPGVAGGSGQSKVMANYMYKAGPSAQGGHLDVLMQQKPQDLSRSFINNPHPAMEPRQGNTKPLFHFNSDQANQQMPSVLPS
QNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPS
SQPAQSLPSQPLLRSPLPLQQKLLLQQMQNQPIAGMGYQVSQQQRQDQHSVVGQNTGPSPSPNPCSNPNTGSGYMNSQQSLLNQQLMGKK
QTLQRQIMEQKQQLLLQQQMLADAEKIAPQDQINRHLSRPPPDYKDQRRNVGNMQPTAQYSGGSSTISLNSNQALANPVSTHTILTPNSS
LLSTSHGTRMPSLSTAVQNMGMYGNLPCNQPNTYSVTSGMNQLTQQRNPKQLLANQNNPMMPRPPTLGPSNNNNVATFGAGSVGNSQQLR
PNLTHSMASMPPQRTSNVMITSNTTAPNWASQEGTSKQQEALTSAGVRFPTGTPAAYTPNQSLQQAVGSQQFSQRAVAPPNQLTPAVQMR
PMNQMSQTLNGQTMGPLRGLNLRPNQLSTQILPNLNQSGTGLNQSRTGINQPPSLTPSNFPSPNQSSRAFQGTDHSSDLAFDFLSQQNDN
MGPALNSDADFIDSLLKTEPGNDDWMKDINLDEILGNNS

--------------------------------------------------------------
>19573_19573_3_CRTC3-MAML2_CRTC3_chr15_91073435_ENST00000268184_MAML2_chr11_95826682_ENST00000524717_length(transcript)=5444nt_BP=136nt
CGCCATGGCCGCCTCGCCGGGCTCGGGCAGCGCCAACCCGCGGAAGTTCAGTGAGAAGATCGCGCTGCACACGCAGAGACAGGCCGAGGA
GACGCGGGCCTTCGAGCAGCTCATGACCGACCTCACCCTGTCGCGGCTCCAGGGTTCCTTGAAAAGAAAACAGGTAGTTAACCTATCTCC
TGCCAACAGCAAGCGACCCAATGGCTTTGTGGACAACTCATTTCTTGATATCAAAAGAATTCGTGTTGGGGAGAATCTCTCTGCAGGACA
AGGTGGCCTCCAAATAAACAATGGACAAAGTCAGATTATGTCAGGGACCTTGCCTATGAGCCAAGCACCCCTGCGAAAGACTAACACTCT
GCCATCCCATACACATTCTCCTGGCAATGGCCTGTTTAACATGGGCTTAAAGGAGGTAAAGAAGGAGCCAGGAGAGACTCTGTCTTGCAG
TAAGCACATGGATGGCCAAATGACCCAAGAGAATATTTTTCCTAATAGGTACGGAGACGACCCTGGAGAACAACTGATGGATCCTGAGCT
GCAGGAACTGTTCAATGAACTGACCAACATATCTGTGCCTCCCATGAGTGACCTTGAACTGGAGAACATGATCAATGCCACCATAAAGCA
GGATGACCCATTTAACATTGACTTGGGTCAGCAAAGCCAGAGGAGCACACCTAGGCCCTCCTTACCCATGGAGAAAATAGTGATCAAAAG
TGAATACTCACCGGGCTTGACTCAGGGCCCCTCAGGCTCTCCTCAGCTGAGGCCCCCATCAGCTGGCCCCGCATTCTCCATGGCCAACTC
TGCCCTCTCCACTTCGTCTCCAATCCCTTCAGTCCCTCAGAGCCAGGCTCAGCCTCAGACAGGCTCCGGAGCAAGCCGGGCCTTGCCAAG
CTGGCAGGAAGTATCCCATGCCCAGCAGCTCAAACAGATAGCTGCTAATCGTCAGCAGCATGCCCGGATGCAGCAGCACCAGCAGCAGCA
CCAGCCTACCAACTGGTCAGCCTTGCCCTCTTCTGCTGGACCATCACCAGGTCCATTTGGGCAGGAGAAAATCCCCAGCCCTTCTTTTGG
TCAGCAGACATTCAGCCCACAGAGCTCCCCCATGCCTGGGGTAGCTGGCGGCAGCGGCCAGTCGAAAGTAATGGCTAACTACATGTACAA
GGCCGGCCCCTCAGCCCAGGGTGGGCACCTAGATGTCCTCATGCAGCAAAAGCCTCAGGATCTCAGTCGAAGTTTTATTAACAACCCGCA
CCCAGCCATGGAGCCCCGTCAGGGCAACACCAAGCCTTTGTTTCATTTTAACTCAGATCAAGCGAACCAGCAGATGCCTTCTGTTTTGCC
TTCCCAGAACAAGCCTTCTCTCCTACACTACACCCAACAGCAACAGCAGCAACAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCA
GCAACAGCAGCAGCAGCAGCAACAGCAACAGCAACAGCAACAGCAGAGTTCAATTTCAGCTCAACAACAGCAACAGCAGCAGAGCTCAAT
TTCAGCCCAACAGCAGCAGCAGCAGCAACAACAGCAGCAGCAGCAGCAACAACAACAGCAACAACAGCAGCAGCAGCAGCAGCAACAACC
ATCTTCTCAGCCTGCCCAATCTCTACCAAGCCAGCCTTTGCTAAGGTCACCTTTGCCACTTCAGCAAAAGCTCCTACTTCAGCAAATGCA
GAATCAGCCCATTGCAGGAATGGGATACCAAGTCTCCCAACAACAGAGACAGGATCAACACTCTGTGGTAGGCCAGAACACAGGCCCCAG
TCCAAGTCCTAACCCCTGCTCAAATCCAAACACTGGAAGTGGTTACATGAACTCCCAGCAATCACTGTTGAATCAGCAATTGATGGGAAA
GAAGCAGACTCTACAGAGGCAGATCATGGAGCAGAAACAGCAACTTCTTCTCCAGCAGCAGATGCTGGCTGACGCGGAGAAAATTGCTCC
ACAAGATCAGATAAACCGACATTTGTCAAGGCCACCTCCAGATTATAAAGACCAAAGAAGAAATGTGGGCAATATGCAACCAACTGCTCA
GTATTCTGGTGGCTCATCCACAATAAGCTTAAACTCTAACCAGGCTTTGGCAAACCCAGTTTCAACACACACCATTTTAACTCCCAATTC
CAGCCTCCTGTCTACTTCTCACGGGACAAGAATGCCATCATTATCTACAGCAGTTCAGAATATGGGGATGTATGGAAATCTGCCTTGTAA
TCAACCTAACACATACAGTGTCACTTCAGGAATGAATCAATTGACCCAACAGAGAAACCCAAAGCAATTGTTAGCAAATCAAAACAACCC
TATGATGCCACGGCCACCTACCTTAGGGCCAAGTAATAATAACAATGTAGCCACTTTTGGAGCTGGATCTGTTGGTAATTCACAACAATT
GAGACCAAATTTAACCCATAGTATGGCAAGCATGCCACCACAGAGAACATCAAACGTAATGATCACATCCAACACAACTGCACCAAACTG
GGCCTCTCAAGAAGGAACAAGCAAACAGCAAGAAGCCCTGACGTCTGCAGGAGTCCGCTTCCCCACAGGTACACCTGCAGCCTATACCCC
AAATCAGTCACTGCAACAGGCAGTAGGTAGCCAGCAATTTTCCCAGAGGGCAGTGGCTCCTCCTAACCAGTTAACACCAGCAGTGCAAAT
GAGACCCATGAACCAAATGAGCCAAACACTAAATGGGCAAACCATGGGTCCCCTCAGGGGTCTGAATCTCAGACCCAATCAGCTAAGCAC
ACAGATTTTGCCTAATTTGAATCAGTCAGGAACAGGGTTGAATCAGTCGAGGACGGGCATCAACCAGCCACCATCCCTGACGCCCAGCAA
TTTTCCTTCACCCAACCAAAGTTCCAGGGCTTTTCAAGGAACTGACCACAGCAGTGACTTAGCTTTTGACTTCCTCAGCCAACAAAATGA
TAACATGGGCCCTGCCCTAAACAGTGATGCTGATTTCATTGATTCTTTATTGAAGACAGAGCCTGGTAATGATGACTGGATGAAAGACAT
CAATCTTGATGAAATCTTGGGGAACAATTCCTAAAGAAGAAAGGGAAGACAATTTACAAACTCCAAGCACTAAAAGGCAGTATATTACAG
AAACTCTGTAGAGGCTGAACTGTTGATGTTCAGGTGGACTACATGAAGATAACATGCTTAAAAATGGAAAGCAGAAAGTAACTGCAGTGA
TGAACATTTTGGTCCAAATTCTTGTTTTAAATCTTACACCTGAAAGTAAAATATTGGGATCACTTTTCCCTGTCTAAACTCCAGGATACA
GTATCCAATTTATCCAAACAGAACTGTGGTGTCAATGTGTAATTAATTGTGTAAAATAGCCTTCCCAAGTTTCTTTTTCCCTGGAAAATA
AAAAAGGTAATAGAACTTGTAGTTTATTTAAACCCCATGTCATGAGGAGGTACTAGTTCCAAGCAACAAACTCCTTAATTTGCTCTAATA
GATAGGTATGGTTTAATCTTTCCATTGTGTCTTTTCATTTAATTTTCCTGAAGCTTGCAGGATAGATTGAAATGTTATAGGTTTGTTTGG
AGTAACCAAACAGTATGCAAATTAAGAAAAAGCCAGAGAACCTAGAAAACATCCAGTGGATTACAGAATTTCTTCCCCATATTCACTCCT
CACTTTTACAATTTTCCCACAATCCTCTACTTCAGTGGGATGCTGTGTCTAGTGATTAAACAAAAATATAGAGCTGTGCAATTTGATTTT
GGCTTCCACAACGAATATCTGAATCCATTCCAAATGAAATTTTAGATATAACAAAGACTTGTCCTAATCATACTGAAATATTGGTGCACA
CCTCTCTGCATTAGATTTCACTTTTTTAAAAAACCCAGTGGACATTGCTATAAATAAGATTTATTTGGCTACAAATAACCTGGGATGTTG
CTTATTATGATTGATGCCTGCTGGTTTGTTCCCAAGCTGAGTGAAATTGAACCTCGTCCTCCCTACTCATTTTGATGACTGAGGCTGGTT
TATAAGAAAAGGAAGTTTGGAGAAGAAAACCGAGATTAGAAAATATCATGTTTTGGTTGGAGATAAGAACCAGGGATGGCAAGTACCAGT
GTGTACAAATGTATTTCACGGAGTTTGAAGGAACGCATAATCAAGAGGGAAAACAATTTGTCCTTCATTGGACGTATTATTTGGATTTGG
GTGAGCAACAAAATGGAATGTGGTCTGTTAGGAGCATTCTGTTTGTTCTTTTGTCCCTGATGTGATGAATCATTGCCACATGCTAGATGG
ACTCTTCATATCCAGGTTTTGTCCCTCAGGGCTGAGCACTGTATTAAAGAGTTTTTGTTGAGTCATTTAACCTTAGTGTCCACATCCAGA
TCAGCTGTAAAATGGGGAAGACGTGTGCTGATTTGGAATGAATGCAAAATATCACTATCATTTTCCTAATTACAGAGGAGCAAAGGTTAT
CTTCAGCCCTTTCAGTTCTATGCTCACATATTCAAATATCAAATGTAATTTAGCTGAAGTTATTTAATAATCAAGTCTTTCAATATCTGT
TCAAAGAAAAAGAACACACTTTGAAAATTCTGCAAAGCTGTCTCCCAGTCTTTAAAATGTCTGGAAGCACTCTCCTTCTTTACAATACCA
ACATCACTGGCCCAGAATCTTCCCTGTGCTAGTTTGTAAATATAAATAAATTACTTGTTTTGTAAACTTTTGTAAAGAATATTTTGGTAG
AAATACTTCAAACATATTCTTTGGGTTATATTTATACATATGTGAAATAAATATACTATCAAAAGGTTATATTTTATACAAAAAGTAAAT
TGCTACCTTTTGTATGCTAATATGCAAAGTTTTGTATAATATGATGGTTTATTTTTAGCTCTACACTTAAACCATAGGTGGTTGAGTGGG
AACTTTTGAAAACTATCAAGAGGCTTGTTAGACAAATTTATATTCTGAAACCTCAATAAGAAAGCATTCCAGGTTTCAATCCTTGTTTTT
TGTCCTGCTCCCAAATTCTTTTTTAAACCCATAGTTCTTGTGTCTTATTTGATTCTTCTGCTGTGCACATTGTATTGGTCCTTGTTGCAT
GTAGTCTACTGTGTGTTTTCCGATTTTATAAGGCAGCATTTCTCCATACAAAAAGAAAAAAAATGATGTACATATAAACGCTTTTGTTGT
ATGGCTCCTCCATGTTACTGTATATATCTGCCAGCACTTCCCAGTTACACTCCTGTGAGTCAGCTTATTTTTACCCTAACATAAATAGTA
TGTTTTGTAGTAGTTATCAAATTTAAGAGATAAAGCAATCAGAATGTTTGGATTTTCTTCTATCTTAATGTGAATTTCATAATTAATGTC
TATTTATTCAGCTATTCATTAAAATACAGGATTCTTTGGGAAAA

>19573_19573_3_CRTC3-MAML2_CRTC3_chr15_91073435_ENST00000268184_MAML2_chr11_95826682_ENST00000524717_length(amino acids)=1029AA_BP=44
MAASPGSGSANPRKFSEKIALHTQRQAEETRAFEQLMTDLTLSRLQGSLKRKQVVNLSPANSKRPNGFVDNSFLDIKRIRVGENLSAGQG
GLQINNGQSQIMSGTLPMSQAPLRKTNTLPSHTHSPGNGLFNMGLKEVKKEPGETLSCSKHMDGQMTQENIFPNRYGDDPGEQLMDPELQ
ELFNELTNISVPPMSDLELENMINATIKQDDPFNIDLGQQSQRSTPRPSLPMEKIVIKSEYSPGLTQGPSGSPQLRPPSAGPAFSMANSA
LSTSSPIPSVPQSQAQPQTGSGASRALPSWQEVSHAQQLKQIAANRQQHARMQQHQQQHQPTNWSALPSSAGPSPGPFGQEKIPSPSFGQ
QTFSPQSSPMPGVAGGSGQSKVMANYMYKAGPSAQGGHLDVLMQQKPQDLSRSFINNPHPAMEPRQGNTKPLFHFNSDQANQQMPSVLPS
QNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPS
SQPAQSLPSQPLLRSPLPLQQKLLLQQMQNQPIAGMGYQVSQQQRQDQHSVVGQNTGPSPSPNPCSNPNTGSGYMNSQQSLLNQQLMGKK
QTLQRQIMEQKQQLLLQQQMLADAEKIAPQDQINRHLSRPPPDYKDQRRNVGNMQPTAQYSGGSSTISLNSNQALANPVSTHTILTPNSS
LLSTSHGTRMPSLSTAVQNMGMYGNLPCNQPNTYSVTSGMNQLTQQRNPKQLLANQNNPMMPRPPTLGPSNNNNVATFGAGSVGNSQQLR
PNLTHSMASMPPQRTSNVMITSNTTAPNWASQEGTSKQQEALTSAGVRFPTGTPAAYTPNQSLQQAVGSQQFSQRAVAPPNQLTPAVQMR
PMNQMSQTLNGQTMGPLRGLNLRPNQLSTQILPNLNQSGTGLNQSRTGINQPPSLTPSNFPSPNQSSRAFQGTDHSSDLAFDFLSQQNDN
MGPALNSDADFIDSLLKTEPGNDDWMKDINLDEILGNNS

--------------------------------------------------------------
>19573_19573_4_CRTC3-MAML2_CRTC3_chr15_91073435_ENST00000420329_MAML2_chr11_95826625_ENST00000524717_length(transcript)=5531nt_BP=279nt
CTCCGGGGCCGCGGCGGCTCCTCTGCCGGGTCGCGCCGGACGACTGGCTTCGGGCGGCGGCCCCGGCGGCCTGTGGACGGACGGGTGGGC
CGAGGTACAGGCCCCACGGCCGCCGTCTCCCGCTTCTGCCCGCGCAGAGTCCGCGCCATGGCCGCCTCGCCGGGCTCGGGCAGCGCCAAC
CCGCGGAAGTTCAGTGAGAAGATCGCGCTGCACACGCAGAGACAGGCCGAGGAGACGCGGGCCTTCGAGCAGCTCATGACCGACCTCACC
CTGTCGCGGGTGGCTCATCCACAATAAGCTTAAACTCTAACCAGGCTTTGGCAAACCCAGTTTCAACACACACCATTTTAACTCCCAATT
CCAGCCTCCTGTCTACTTCTCACGGGACAAGAATGCCATCATTATCTACAGCAGTTCAGAATATGGGGATGTATGGAAATCTGCCTTGTA
ATCAACCTAACACATACAGTGTCACTTCAGGAATGAATCAATTGACCCAACAGAGAAACCCAAAGCAATTGTTAGCAAATCAAAACAACC
CTATGATGCCACGGCCACCTACCTTAGGGCCAAGTAATAATAACAATGTAGCCACTTTTGGAGCTGGATCTGTTGGTAATTCACAACAAT
TGAGACCAAATTTAACCCATAGTATGGCAAGCATGCCACCACAGAGAACATCAAACGTAATGATCACATCCAACACAACTGCACCAAACT
GGGCCTCTCAAGAAGGAACAAGCAAACAGCAAGAAGCCCTGACGTCTGCAGGAGTCCGCTTCCCCACAGGTACACCTGCAGCCTATACCC
CAAATCAGTCACTGCAACAGGCAGTAGGTAGCCAGCAATTTTCCCAGAGGGCAGTGGCTCCTCCTAACCAGTTAACACCAGCAGTGCAAA
TGAGACCCATGAACCAAATGAGCCAAACACTAAATGGGCAAACCATGGGTCCCCTCAGGGGTCTGAATCTCAGACCCAATCAGCTAAGCA
CACAGATTTTGCCTAATTTGAATCAGTCAGGAACAGGGTTGAATCAGTCGAGGACGGGCATCAACCAGCCACCATCCCTGACGCCCAGCA
ATTTTCCTTCACCCAACCAAAGTTCCAGGGCTTTTCAAGGAACTGACCACAGCAGTGACTTAGCTTTTGACTTCCTCAGCCAACAAAATG
ATAACATGGGCCCTGCCCTAAACAGTGATGCTGATTTCATTGATTCTTTATTGAAGACAGAGCCTGGTAATGATGACTGGATGAAAGACA
TCAATCTTGATGAAATCTTGGGGAACAATTCCTAAAGAAGAAAGGGAAGACAATTTACAAACTCCAAGCACTAAAAGGCAGTATATTACA
GAAACTCTGTAGAGGCTGAACTGTTGATGTTCAGGTGGACTACATGAAGATAACATGCTTAAAAATGGAAAGCAGAAAGTAACTGCAGTG
ATGAACATTTTGGTCCAAATTCTTGTTTTAAATCTTACACCTGAAAGTAAAATATTGGGATCACTTTTCCCTGTCTAAACTCCAGGATAC
AGTATCCAATTTATCCAAACAGAACTGTGGTGTCAATGTGTAATTAATTGTGTAAAATAGCCTTCCCAAGTTTCTTTTTCCCTGGAAAAT
AAAAAAGGTAATAGAACTTGTAGTTTATTTAAACCCCATGTCATGAGGAGGTACTAGTTCCAAGCAACAAACTCCTTAATTTGCTCTAAT
AGATAGGTATGGTTTAATCTTTCCATTGTGTCTTTTCATTTAATTTTCCTGAAGCTTGCAGGATAGATTGAAATGTTATAGGTTTGTTTG
GAGTAACCAAACAGTATGCAAATTAAGAAAAAGCCAGAGAACCTAGAAAACATCCAGTGGATTACAGAATTTCTTCCCCATATTCACTCC
TCACTTTTACAATTTTCCCACAATCCTCTACTTCAGTGGGATGCTGTGTCTAGTGATTAAACAAAAATATAGAGCTGTGCAATTTGATTT
TGGCTTCCACAACGAATATCTGAATCCATTCCAAATGAAATTTTAGATATAACAAAGACTTGTCCTAATCATACTGAAATATTGGTGCAC
ACCTCTCTGCATTAGATTTCACTTTTTTAAAAAACCCAGTGGACATTGCTATAAATAAGATTTATTTGGCTACAAATAACCTGGGATGTT
GCTTATTATGATTGATGCCTGCTGGTTTGTTCCCAAGCTGAGTGAAATTGAACCTCGTCCTCCCTACTCATTTTGATGACTGAGGCTGGT
TTATAAGAAAAGGAAGTTTGGAGAAGAAAACCGAGATTAGAAAATATCATGTTTTGGTTGGAGATAAGAACCAGGGATGGCAAGTACCAG
TGTGTACAAATGTATTTCACGGAGTTTGAAGGAACGCATAATCAAGAGGGAAAACAATTTGTCCTTCATTGGACGTATTATTTGGATTTG
GGTGAGCAACAAAATGGAATGTGGTCTGTTAGGAGCATTCTGTTTGTTCTTTTGTCCCTGATGTGATGAATCATTGCCACATGCTAGATG
GACTCTTCATATCCAGGTTTTGTCCCTCAGGGCTGAGCACTGTATTAAAGAGTTTTTGTTGAGTCATTTAACCTTAGTGTCCACATCCAG
ATCAGCTGTAAAATGGGGAAGACGTGTGCTGATTTGGAATGAATGCAAAATATCACTATCATTTTCCTAATTACAGAGGAGCAAAGGTTA
TCTTCAGCCCTTTCAGTTCTATGCTCACATATTCAAATATCAAATGTAATTTAGCTGAAGTTATTTAATAATCAAGTCTTTCAATATCTG
TTCAAAGAAAAAGAACACACTTTGAAAATTCTGCAAAGCTGTCTCCCAGTCTTTAAAATGTCTGGAAGCACTCTCCTTCTTTACAATACC
AACATCACTGGCCCAGAATCTTCCCTGTGCTAGTTTGTAAATATAAATAAATTACTTGTTTTGTAAACTTTTGTAAAGAATATTTTGGTA
GAAATACTTCAAACATATTCTTTGGGTTATATTTATACATATGTGAAATAAATATACTATCAAAAGGTTATATTTTATACAAAAAGTAAA
TTGCTACCTTTTGTATGCTAATATGCAAAGTTTTGTATAATATGATGGTTTATTTTTAGCTCTACACTTAAACCATAGGTGGTTGAGTGG
GAACTTTTGAAAACTATCAAGAGGCTTGTTAGACAAATTTATATTCTGAAACCTCAATAAGAAAGCATTCCAGGTTTCAATCCTTGTTTT
TTGTCCTGCTCCCAAATTCTTTTTTAAACCCATAGTTCTTGTGTCTTATTTGATTCTTCTGCTGTGCACATTGTATTGGTCCTTGTTGCA
TGTAGTCTACTGTGTGTTTTCCGATTTTATAAGGCAGCATTTCTCCATACAAAAAGAAAAAAAATGATGTACATATAAACGCTTTTGTTG
TATGGCTCCTCCATGTTACTGTATATATCTGCCAGCACTTCCCAGTTACACTCCTGTGAGTCAGCTTATTTTTACCCTAACATAAATAGT
ATGTTTTGTAGTAGTTATCAAATTTAAGAGATAAAGCAATCAGAATGTTTGGATTTTCTTCTATCTTAATGTGAATTTCATAATTAATGT
CTATTTATTCAGCTATTCATTAAAATACAGGATTCTTTGGGAAAAGAGAAAATTGCTCCACAAGATCAGATAAACCGACATTTGTCAAGG
CCACCTCCAGATTATAAAGACCAAAGAAGAAATGTGGGCAATATGCAACCAACTGCTCAGTATTCTGGATCAACACTCTGTGGTAGGCCA
GAACACAGGCCCCAGTCCAAGTCCTAACCCCTGCTCAAATCCAAACACTGGAAGTGGTTACATGAACTCCCAGCAATCACTGTTGAATCA
GCAATTGATGGGAAAGAAGCAGACTCTACAGAGGCAGATCATGGAGCAGAAACAGCAACTTCTTCTCCAGCAGCAGATGCTGGCTGACGC
GGCGACCCAATGGCTTTGTGGACAACTCATTTCTTGATATCAAAAGAATTCGTGTTGGGGAGAATCTCTCTGCAGGACAAGGTGGCCTCC
AAATAAACAATGGACAAAGTCAGATTATGTCAGGGACCTTGCCTATGAGCCAAGCACCCCTGCGAAAGACTAACACTCTGCCATCCCATA
CACATTCTCCTGGCAATGGCCTGTTTAACATGGGCTTAAAGGAGGTAAAGAAGGAGCCAGGAGAGACTCTGTCTTGCAGTAAGCACATGG
ATGGCCAAATGACCCAAGAGAATATTTTTCCTAATAGGTACGGAGACGACCCTGGAGAACAACTGATGGATCCTGAGCTGCAGGAACTGT
TCAATGAACTGACCAACATATCTGTGCCTCCCATGAGTGACCTTGAACTGGAGAACATGATCAATGCCACCATAAAGCAGGATGACCCAT
TTAACATTGACTTGGGTCAGCAAAGCCAGAGGAGCACACCTAGGCCCTCCTTACCCATGGAGAAAATAGTGATCAAAAGTGAATACTCAC
CGGGCTTGACTCAGGGCCCCTCAGGCTCTCCTCAGCTGAGGCCCCCATCAGCTGGCCCCGCATTCTCCATGGCCAACTCTGCCCTCTCCA
CTTCGTCTCCAATCCCTTCAGTCCCTCAGAGCCAGGCTCAGCCTCAGACAGGCTCCGGAGCAAGCCGGGCCTTGCCAAGCTGGCAGGAAG
TATCCCATGCCCAGCAGCTCAAACAGATAGCTGCTAATCGTCAGCAGCATGCCCGGATGCAGCAGCACCAGCAGCAGCACCAGCCTACCA
ACTGGTCAGCCTTGCCCTCTTCTGCTGGACCATCACCAGGTCCATTTGGGCAGGAGAAAATCCCCAGCCCTTCTTTTGGTCAGCAGACAT
TCAGCCCACAGAGCTCCCCCATGCCTGGGGTAGCTGGCGGCAGCGGCCAGTCGAAAGTAATGGCTAACTACATGTACAAGGCCGGCCCCT
CAGCCCAGGGTGGGCACCTAGATGTCCTCATGCAGCAAAAGCCTCAGGATCTCAGTCGAAGTTTTATTAACAACCCGCACCCAGCCATGG
AGCCCCGTCAGGGCAACACCAAGCCTTTGTTTCATTTTAACTCAGATCAAGCGAACCAGCAGATGCCTTCTGTTTTGCCTTCCCAGAACA
AGCCTTCTCTCCTACACTACACCCAACAGCAACAGCAGCAACAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAACAGCAGC
AGCAGCAGCAACAGCAACAGCAACAGCAACAGCAGAGTTCAATTTCAGCTCAACAACAGCAACAGCAGCAGAGCTCAATTTCAGCCCAAC
AGCAGCAGCAGCAGCAACAACAGCAGCAGCAGCAGCAACAACAACAGCAACAACAGCAGCAGCAGCAGCAGCAACAACCATCTTCTCAGC
CTGCCCAATCTCTACCAAGCCAGCCTTTGCTAAGGTCACCTTTGCCACTTCAGCAAAAGCTCCTACTTCAGCAAATGCAGAATCAGCCCA
TTGCAGGAATGGGATACCAAGTCTCCCAACAACAGAGACAG

>19573_19573_4_CRTC3-MAML2_CRTC3_chr15_91073435_ENST00000420329_MAML2_chr11_95826625_ENST00000524717_length(amino acids)=526AA_BP=3
MTRRPNGFVDNSFLDIKRIRVGENLSAGQGGLQINNGQSQIMSGTLPMSQAPLRKTNTLPSHTHSPGNGLFNMGLKEVKKEPGETLSCSK
HMDGQMTQENIFPNRYGDDPGEQLMDPELQELFNELTNISVPPMSDLELENMINATIKQDDPFNIDLGQQSQRSTPRPSLPMEKIVIKSE
YSPGLTQGPSGSPQLRPPSAGPAFSMANSALSTSSPIPSVPQSQAQPQTGSGASRALPSWQEVSHAQQLKQIAANRQQHARMQQHQQQHQ
PTNWSALPSSAGPSPGPFGQEKIPSPSFGQQTFSPQSSPMPGVAGGSGQSKVMANYMYKAGPSAQGGHLDVLMQQKPQDLSRSFINNPHP
AMEPRQGNTKPLFHFNSDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSIS
AQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLLQQMQNQPIAGMGYQVSQQQRQ

--------------------------------------------------------------
>19573_19573_5_CRTC3-MAML2_CRTC3_chr15_91073435_ENST00000420329_MAML2_chr11_95826681_ENST00000524717_length(transcript)=5587nt_BP=279nt
CTCCGGGGCCGCGGCGGCTCCTCTGCCGGGTCGCGCCGGACGACTGGCTTCGGGCGGCGGCCCCGGCGGCCTGTGGACGGACGGGTGGGC
CGAGGTACAGGCCCCACGGCCGCCGTCTCCCGCTTCTGCCCGCGCAGAGTCCGCGCCATGGCCGCCTCGCCGGGCTCGGGCAGCGCCAAC
CCGCGGAAGTTCAGTGAGAAGATCGCGCTGCACACGCAGAGACAGGCCGAGGAGACGCGGGCCTTCGAGCAGCTCATGACCGACCTCACC
CTGTCGCGGCTCCAGGGTTCCTTGAAAAGAAAACAGGTAGTTAACCTATCTCCTGCCAACAGCAAGCGACCCAATGGCTTTGTGGACAAC
TCATTTCTTGATATCAAAAGAATTCGTGTTGGGGAGAATCTCTCTGCAGGACAAGGTGGCCTCCAAATAAACAATGGACAAAGTCAGATT
ATGTCAGGGACCTTGCCTATGAGCCAAGCACCCCTGCGAAAGACTAACACTCTGCCATCCCATACACATTCTCCTGGCAATGGCCTGTTT
AACATGGGCTTAAAGGAGGTAAAGAAGGAGCCAGGAGAGACTCTGTCTTGCAGTAAGCACATGGATGGCCAAATGACCCAAGAGAATATT
TTTCCTAATAGGTACGGAGACGACCCTGGAGAACAACTGATGGATCCTGAGCTGCAGGAACTGTTCAATGAACTGACCAACATATCTGTG
CCTCCCATGAGTGACCTTGAACTGGAGAACATGATCAATGCCACCATAAAGCAGGATGACCCATTTAACATTGACTTGGGTCAGCAAAGC
CAGAGGAGCACACCTAGGCCCTCCTTACCCATGGAGAAAATAGTGATCAAAAGTGAATACTCACCGGGCTTGACTCAGGGCCCCTCAGGC
TCTCCTCAGCTGAGGCCCCCATCAGCTGGCCCCGCATTCTCCATGGCCAACTCTGCCCTCTCCACTTCGTCTCCAATCCCTTCAGTCCCT
CAGAGCCAGGCTCAGCCTCAGACAGGCTCCGGAGCAAGCCGGGCCTTGCCAAGCTGGCAGGAAGTATCCCATGCCCAGCAGCTCAAACAG
ATAGCTGCTAATCGTCAGCAGCATGCCCGGATGCAGCAGCACCAGCAGCAGCACCAGCCTACCAACTGGTCAGCCTTGCCCTCTTCTGCT
GGACCATCACCAGGTCCATTTGGGCAGGAGAAAATCCCCAGCCCTTCTTTTGGTCAGCAGACATTCAGCCCACAGAGCTCCCCCATGCCT
GGGGTAGCTGGCGGCAGCGGCCAGTCGAAAGTAATGGCTAACTACATGTACAAGGCCGGCCCCTCAGCCCAGGGTGGGCACCTAGATGTC
CTCATGCAGCAAAAGCCTCAGGATCTCAGTCGAAGTTTTATTAACAACCCGCACCCAGCCATGGAGCCCCGTCAGGGCAACACCAAGCCT
TTGTTTCATTTTAACTCAGATCAAGCGAACCAGCAGATGCCTTCTGTTTTGCCTTCCCAGAACAAGCCTTCTCTCCTACACTACACCCAA
CAGCAACAGCAGCAACAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAACAGCAGCAGCAGCAGCAACAGCAACAGCAACAG
CAACAGCAGAGTTCAATTTCAGCTCAACAACAGCAACAGCAGCAGAGCTCAATTTCAGCCCAACAGCAGCAGCAGCAGCAACAACAGCAG
CAGCAGCAGCAACAACAACAGCAACAACAGCAGCAGCAGCAGCAGCAACAACCATCTTCTCAGCCTGCCCAATCTCTACCAAGCCAGCCT
TTGCTAAGGTCACCTTTGCCACTTCAGCAAAAGCTCCTACTTCAGCAAATGCAGAATCAGCCCATTGCAGGAATGGGATACCAAGTCTCC
CAACAACAGAGACAGGATCAACACTCTGTGGTAGGCCAGAACACAGGCCCCAGTCCAAGTCCTAACCCCTGCTCAAATCCAAACACTGGA
AGTGGTTACATGAACTCCCAGCAATCACTGTTGAATCAGCAATTGATGGGAAAGAAGCAGACTCTACAGAGGCAGATCATGGAGCAGAAA
CAGCAACTTCTTCTCCAGCAGCAGATGCTGGCTGACGCGGAGAAAATTGCTCCACAAGATCAGATAAACCGACATTTGTCAAGGCCACCT
CCAGATTATAAAGACCAAAGAAGAAATGTGGGCAATATGCAACCAACTGCTCAGTATTCTGGTGGCTCATCCACAATAAGCTTAAACTCT
AACCAGGCTTTGGCAAACCCAGTTTCAACACACACCATTTTAACTCCCAATTCCAGCCTCCTGTCTACTTCTCACGGGACAAGAATGCCA
TCATTATCTACAGCAGTTCAGAATATGGGGATGTATGGAAATCTGCCTTGTAATCAACCTAACACATACAGTGTCACTTCAGGAATGAAT
CAATTGACCCAACAGAGAAACCCAAAGCAATTGTTAGCAAATCAAAACAACCCTATGATGCCACGGCCACCTACCTTAGGGCCAAGTAAT
AATAACAATGTAGCCACTTTTGGAGCTGGATCTGTTGGTAATTCACAACAATTGAGACCAAATTTAACCCATAGTATGGCAAGCATGCCA
CCACAGAGAACATCAAACGTAATGATCACATCCAACACAACTGCACCAAACTGGGCCTCTCAAGAAGGAACAAGCAAACAGCAAGAAGCC
CTGACGTCTGCAGGAGTCCGCTTCCCCACAGGTACACCTGCAGCCTATACCCCAAATCAGTCACTGCAACAGGCAGTAGGTAGCCAGCAA
TTTTCCCAGAGGGCAGTGGCTCCTCCTAACCAGTTAACACCAGCAGTGCAAATGAGACCCATGAACCAAATGAGCCAAACACTAAATGGG
CAAACCATGGGTCCCCTCAGGGGTCTGAATCTCAGACCCAATCAGCTAAGCACACAGATTTTGCCTAATTTGAATCAGTCAGGAACAGGG
TTGAATCAGTCGAGGACGGGCATCAACCAGCCACCATCCCTGACGCCCAGCAATTTTCCTTCACCCAACCAAAGTTCCAGGGCTTTTCAA
GGAACTGACCACAGCAGTGACTTAGCTTTTGACTTCCTCAGCCAACAAAATGATAACATGGGCCCTGCCCTAAACAGTGATGCTGATTTC
ATTGATTCTTTATTGAAGACAGAGCCTGGTAATGATGACTGGATGAAAGACATCAATCTTGATGAAATCTTGGGGAACAATTCCTAAAGA
AGAAAGGGAAGACAATTTACAAACTCCAAGCACTAAAAGGCAGTATATTACAGAAACTCTGTAGAGGCTGAACTGTTGATGTTCAGGTGG
ACTACATGAAGATAACATGCTTAAAAATGGAAAGCAGAAAGTAACTGCAGTGATGAACATTTTGGTCCAAATTCTTGTTTTAAATCTTAC
ACCTGAAAGTAAAATATTGGGATCACTTTTCCCTGTCTAAACTCCAGGATACAGTATCCAATTTATCCAAACAGAACTGTGGTGTCAATG
TGTAATTAATTGTGTAAAATAGCCTTCCCAAGTTTCTTTTTCCCTGGAAAATAAAAAAGGTAATAGAACTTGTAGTTTATTTAAACCCCA
TGTCATGAGGAGGTACTAGTTCCAAGCAACAAACTCCTTAATTTGCTCTAATAGATAGGTATGGTTTAATCTTTCCATTGTGTCTTTTCA
TTTAATTTTCCTGAAGCTTGCAGGATAGATTGAAATGTTATAGGTTTGTTTGGAGTAACCAAACAGTATGCAAATTAAGAAAAAGCCAGA
GAACCTAGAAAACATCCAGTGGATTACAGAATTTCTTCCCCATATTCACTCCTCACTTTTACAATTTTCCCACAATCCTCTACTTCAGTG
GGATGCTGTGTCTAGTGATTAAACAAAAATATAGAGCTGTGCAATTTGATTTTGGCTTCCACAACGAATATCTGAATCCATTCCAAATGA
AATTTTAGATATAACAAAGACTTGTCCTAATCATACTGAAATATTGGTGCACACCTCTCTGCATTAGATTTCACTTTTTTAAAAAACCCA
GTGGACATTGCTATAAATAAGATTTATTTGGCTACAAATAACCTGGGATGTTGCTTATTATGATTGATGCCTGCTGGTTTGTTCCCAAGC
TGAGTGAAATTGAACCTCGTCCTCCCTACTCATTTTGATGACTGAGGCTGGTTTATAAGAAAAGGAAGTTTGGAGAAGAAAACCGAGATT
AGAAAATATCATGTTTTGGTTGGAGATAAGAACCAGGGATGGCAAGTACCAGTGTGTACAAATGTATTTCACGGAGTTTGAAGGAACGCA
TAATCAAGAGGGAAAACAATTTGTCCTTCATTGGACGTATTATTTGGATTTGGGTGAGCAACAAAATGGAATGTGGTCTGTTAGGAGCAT
TCTGTTTGTTCTTTTGTCCCTGATGTGATGAATCATTGCCACATGCTAGATGGACTCTTCATATCCAGGTTTTGTCCCTCAGGGCTGAGC
ACTGTATTAAAGAGTTTTTGTTGAGTCATTTAACCTTAGTGTCCACATCCAGATCAGCTGTAAAATGGGGAAGACGTGTGCTGATTTGGA
ATGAATGCAAAATATCACTATCATTTTCCTAATTACAGAGGAGCAAAGGTTATCTTCAGCCCTTTCAGTTCTATGCTCACATATTCAAAT
ATCAAATGTAATTTAGCTGAAGTTATTTAATAATCAAGTCTTTCAATATCTGTTCAAAGAAAAAGAACACACTTTGAAAATTCTGCAAAG
CTGTCTCCCAGTCTTTAAAATGTCTGGAAGCACTCTCCTTCTTTACAATACCAACATCACTGGCCCAGAATCTTCCCTGTGCTAGTTTGT
AAATATAAATAAATTACTTGTTTTGTAAACTTTTGTAAAGAATATTTTGGTAGAAATACTTCAAACATATTCTTTGGGTTATATTTATAC
ATATGTGAAATAAATATACTATCAAAAGGTTATATTTTATACAAAAAGTAAATTGCTACCTTTTGTATGCTAATATGCAAAGTTTTGTAT
AATATGATGGTTTATTTTTAGCTCTACACTTAAACCATAGGTGGTTGAGTGGGAACTTTTGAAAACTATCAAGAGGCTTGTTAGACAAAT
TTATATTCTGAAACCTCAATAAGAAAGCATTCCAGGTTTCAATCCTTGTTTTTTGTCCTGCTCCCAAATTCTTTTTTAAACCCATAGTTC
TTGTGTCTTATTTGATTCTTCTGCTGTGCACATTGTATTGGTCCTTGTTGCATGTAGTCTACTGTGTGTTTTCCGATTTTATAAGGCAGC
ATTTCTCCATACAAAAAGAAAAAAAATGATGTACATATAAACGCTTTTGTTGTATGGCTCCTCCATGTTACTGTATATATCTGCCAGCAC
TTCCCAGTTACACTCCTGTGAGTCAGCTTATTTTTACCCTAACATAAATAGTATGTTTTGTAGTAGTTATCAAATTTAAGAGATAAAGCA
ATCAGAATGTTTGGATTTTCTTCTATCTTAATGTGAATTTCATAATTAATGTCTATTTATTCAGCTATTCATTAAAATACAGGATTCTTT
GGGAAAA

>19573_19573_5_CRTC3-MAML2_CRTC3_chr15_91073435_ENST00000420329_MAML2_chr11_95826681_ENST00000524717_length(amino acids)=1029AA_BP=44
MAASPGSGSANPRKFSEKIALHTQRQAEETRAFEQLMTDLTLSRLQGSLKRKQVVNLSPANSKRPNGFVDNSFLDIKRIRVGENLSAGQG
GLQINNGQSQIMSGTLPMSQAPLRKTNTLPSHTHSPGNGLFNMGLKEVKKEPGETLSCSKHMDGQMTQENIFPNRYGDDPGEQLMDPELQ
ELFNELTNISVPPMSDLELENMINATIKQDDPFNIDLGQQSQRSTPRPSLPMEKIVIKSEYSPGLTQGPSGSPQLRPPSAGPAFSMANSA
LSTSSPIPSVPQSQAQPQTGSGASRALPSWQEVSHAQQLKQIAANRQQHARMQQHQQQHQPTNWSALPSSAGPSPGPFGQEKIPSPSFGQ
QTFSPQSSPMPGVAGGSGQSKVMANYMYKAGPSAQGGHLDVLMQQKPQDLSRSFINNPHPAMEPRQGNTKPLFHFNSDQANQQMPSVLPS
QNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPS
SQPAQSLPSQPLLRSPLPLQQKLLLQQMQNQPIAGMGYQVSQQQRQDQHSVVGQNTGPSPSPNPCSNPNTGSGYMNSQQSLLNQQLMGKK
QTLQRQIMEQKQQLLLQQQMLADAEKIAPQDQINRHLSRPPPDYKDQRRNVGNMQPTAQYSGGSSTISLNSNQALANPVSTHTILTPNSS
LLSTSHGTRMPSLSTAVQNMGMYGNLPCNQPNTYSVTSGMNQLTQQRNPKQLLANQNNPMMPRPPTLGPSNNNNVATFGAGSVGNSQQLR
PNLTHSMASMPPQRTSNVMITSNTTAPNWASQEGTSKQQEALTSAGVRFPTGTPAAYTPNQSLQQAVGSQQFSQRAVAPPNQLTPAVQMR
PMNQMSQTLNGQTMGPLRGLNLRPNQLSTQILPNLNQSGTGLNQSRTGINQPPSLTPSNFPSPNQSSRAFQGTDHSSDLAFDFLSQQNDN
MGPALNSDADFIDSLLKTEPGNDDWMKDINLDEILGNNS

--------------------------------------------------------------
>19573_19573_6_CRTC3-MAML2_CRTC3_chr15_91073435_ENST00000420329_MAML2_chr11_95826682_ENST00000524717_length(transcript)=5587nt_BP=279nt
CTCCGGGGCCGCGGCGGCTCCTCTGCCGGGTCGCGCCGGACGACTGGCTTCGGGCGGCGGCCCCGGCGGCCTGTGGACGGACGGGTGGGC
CGAGGTACAGGCCCCACGGCCGCCGTCTCCCGCTTCTGCCCGCGCAGAGTCCGCGCCATGGCCGCCTCGCCGGGCTCGGGCAGCGCCAAC
CCGCGGAAGTTCAGTGAGAAGATCGCGCTGCACACGCAGAGACAGGCCGAGGAGACGCGGGCCTTCGAGCAGCTCATGACCGACCTCACC
CTGTCGCGGCTCCAGGGTTCCTTGAAAAGAAAACAGGTAGTTAACCTATCTCCTGCCAACAGCAAGCGACCCAATGGCTTTGTGGACAAC
TCATTTCTTGATATCAAAAGAATTCGTGTTGGGGAGAATCTCTCTGCAGGACAAGGTGGCCTCCAAATAAACAATGGACAAAGTCAGATT
ATGTCAGGGACCTTGCCTATGAGCCAAGCACCCCTGCGAAAGACTAACACTCTGCCATCCCATACACATTCTCCTGGCAATGGCCTGTTT
AACATGGGCTTAAAGGAGGTAAAGAAGGAGCCAGGAGAGACTCTGTCTTGCAGTAAGCACATGGATGGCCAAATGACCCAAGAGAATATT
TTTCCTAATAGGTACGGAGACGACCCTGGAGAACAACTGATGGATCCTGAGCTGCAGGAACTGTTCAATGAACTGACCAACATATCTGTG
CCTCCCATGAGTGACCTTGAACTGGAGAACATGATCAATGCCACCATAAAGCAGGATGACCCATTTAACATTGACTTGGGTCAGCAAAGC
CAGAGGAGCACACCTAGGCCCTCCTTACCCATGGAGAAAATAGTGATCAAAAGTGAATACTCACCGGGCTTGACTCAGGGCCCCTCAGGC
TCTCCTCAGCTGAGGCCCCCATCAGCTGGCCCCGCATTCTCCATGGCCAACTCTGCCCTCTCCACTTCGTCTCCAATCCCTTCAGTCCCT
CAGAGCCAGGCTCAGCCTCAGACAGGCTCCGGAGCAAGCCGGGCCTTGCCAAGCTGGCAGGAAGTATCCCATGCCCAGCAGCTCAAACAG
ATAGCTGCTAATCGTCAGCAGCATGCCCGGATGCAGCAGCACCAGCAGCAGCACCAGCCTACCAACTGGTCAGCCTTGCCCTCTTCTGCT
GGACCATCACCAGGTCCATTTGGGCAGGAGAAAATCCCCAGCCCTTCTTTTGGTCAGCAGACATTCAGCCCACAGAGCTCCCCCATGCCT
GGGGTAGCTGGCGGCAGCGGCCAGTCGAAAGTAATGGCTAACTACATGTACAAGGCCGGCCCCTCAGCCCAGGGTGGGCACCTAGATGTC
CTCATGCAGCAAAAGCCTCAGGATCTCAGTCGAAGTTTTATTAACAACCCGCACCCAGCCATGGAGCCCCGTCAGGGCAACACCAAGCCT
TTGTTTCATTTTAACTCAGATCAAGCGAACCAGCAGATGCCTTCTGTTTTGCCTTCCCAGAACAAGCCTTCTCTCCTACACTACACCCAA
CAGCAACAGCAGCAACAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAACAGCAGCAGCAGCAGCAACAGCAACAGCAACAG
CAACAGCAGAGTTCAATTTCAGCTCAACAACAGCAACAGCAGCAGAGCTCAATTTCAGCCCAACAGCAGCAGCAGCAGCAACAACAGCAG
CAGCAGCAGCAACAACAACAGCAACAACAGCAGCAGCAGCAGCAGCAACAACCATCTTCTCAGCCTGCCCAATCTCTACCAAGCCAGCCT
TTGCTAAGGTCACCTTTGCCACTTCAGCAAAAGCTCCTACTTCAGCAAATGCAGAATCAGCCCATTGCAGGAATGGGATACCAAGTCTCC
CAACAACAGAGACAGGATCAACACTCTGTGGTAGGCCAGAACACAGGCCCCAGTCCAAGTCCTAACCCCTGCTCAAATCCAAACACTGGA
AGTGGTTACATGAACTCCCAGCAATCACTGTTGAATCAGCAATTGATGGGAAAGAAGCAGACTCTACAGAGGCAGATCATGGAGCAGAAA
CAGCAACTTCTTCTCCAGCAGCAGATGCTGGCTGACGCGGAGAAAATTGCTCCACAAGATCAGATAAACCGACATTTGTCAAGGCCACCT
CCAGATTATAAAGACCAAAGAAGAAATGTGGGCAATATGCAACCAACTGCTCAGTATTCTGGTGGCTCATCCACAATAAGCTTAAACTCT
AACCAGGCTTTGGCAAACCCAGTTTCAACACACACCATTTTAACTCCCAATTCCAGCCTCCTGTCTACTTCTCACGGGACAAGAATGCCA
TCATTATCTACAGCAGTTCAGAATATGGGGATGTATGGAAATCTGCCTTGTAATCAACCTAACACATACAGTGTCACTTCAGGAATGAAT
CAATTGACCCAACAGAGAAACCCAAAGCAATTGTTAGCAAATCAAAACAACCCTATGATGCCACGGCCACCTACCTTAGGGCCAAGTAAT
AATAACAATGTAGCCACTTTTGGAGCTGGATCTGTTGGTAATTCACAACAATTGAGACCAAATTTAACCCATAGTATGGCAAGCATGCCA
CCACAGAGAACATCAAACGTAATGATCACATCCAACACAACTGCACCAAACTGGGCCTCTCAAGAAGGAACAAGCAAACAGCAAGAAGCC
CTGACGTCTGCAGGAGTCCGCTTCCCCACAGGTACACCTGCAGCCTATACCCCAAATCAGTCACTGCAACAGGCAGTAGGTAGCCAGCAA
TTTTCCCAGAGGGCAGTGGCTCCTCCTAACCAGTTAACACCAGCAGTGCAAATGAGACCCATGAACCAAATGAGCCAAACACTAAATGGG
CAAACCATGGGTCCCCTCAGGGGTCTGAATCTCAGACCCAATCAGCTAAGCACACAGATTTTGCCTAATTTGAATCAGTCAGGAACAGGG
TTGAATCAGTCGAGGACGGGCATCAACCAGCCACCATCCCTGACGCCCAGCAATTTTCCTTCACCCAACCAAAGTTCCAGGGCTTTTCAA
GGAACTGACCACAGCAGTGACTTAGCTTTTGACTTCCTCAGCCAACAAAATGATAACATGGGCCCTGCCCTAAACAGTGATGCTGATTTC
ATTGATTCTTTATTGAAGACAGAGCCTGGTAATGATGACTGGATGAAAGACATCAATCTTGATGAAATCTTGGGGAACAATTCCTAAAGA
AGAAAGGGAAGACAATTTACAAACTCCAAGCACTAAAAGGCAGTATATTACAGAAACTCTGTAGAGGCTGAACTGTTGATGTTCAGGTGG
ACTACATGAAGATAACATGCTTAAAAATGGAAAGCAGAAAGTAACTGCAGTGATGAACATTTTGGTCCAAATTCTTGTTTTAAATCTTAC
ACCTGAAAGTAAAATATTGGGATCACTTTTCCCTGTCTAAACTCCAGGATACAGTATCCAATTTATCCAAACAGAACTGTGGTGTCAATG
TGTAATTAATTGTGTAAAATAGCCTTCCCAAGTTTCTTTTTCCCTGGAAAATAAAAAAGGTAATAGAACTTGTAGTTTATTTAAACCCCA
TGTCATGAGGAGGTACTAGTTCCAAGCAACAAACTCCTTAATTTGCTCTAATAGATAGGTATGGTTTAATCTTTCCATTGTGTCTTTTCA
TTTAATTTTCCTGAAGCTTGCAGGATAGATTGAAATGTTATAGGTTTGTTTGGAGTAACCAAACAGTATGCAAATTAAGAAAAAGCCAGA
GAACCTAGAAAACATCCAGTGGATTACAGAATTTCTTCCCCATATTCACTCCTCACTTTTACAATTTTCCCACAATCCTCTACTTCAGTG
GGATGCTGTGTCTAGTGATTAAACAAAAATATAGAGCTGTGCAATTTGATTTTGGCTTCCACAACGAATATCTGAATCCATTCCAAATGA
AATTTTAGATATAACAAAGACTTGTCCTAATCATACTGAAATATTGGTGCACACCTCTCTGCATTAGATTTCACTTTTTTAAAAAACCCA
GTGGACATTGCTATAAATAAGATTTATTTGGCTACAAATAACCTGGGATGTTGCTTATTATGATTGATGCCTGCTGGTTTGTTCCCAAGC
TGAGTGAAATTGAACCTCGTCCTCCCTACTCATTTTGATGACTGAGGCTGGTTTATAAGAAAAGGAAGTTTGGAGAAGAAAACCGAGATT
AGAAAATATCATGTTTTGGTTGGAGATAAGAACCAGGGATGGCAAGTACCAGTGTGTACAAATGTATTTCACGGAGTTTGAAGGAACGCA
TAATCAAGAGGGAAAACAATTTGTCCTTCATTGGACGTATTATTTGGATTTGGGTGAGCAACAAAATGGAATGTGGTCTGTTAGGAGCAT
TCTGTTTGTTCTTTTGTCCCTGATGTGATGAATCATTGCCACATGCTAGATGGACTCTTCATATCCAGGTTTTGTCCCTCAGGGCTGAGC
ACTGTATTAAAGAGTTTTTGTTGAGTCATTTAACCTTAGTGTCCACATCCAGATCAGCTGTAAAATGGGGAAGACGTGTGCTGATTTGGA
ATGAATGCAAAATATCACTATCATTTTCCTAATTACAGAGGAGCAAAGGTTATCTTCAGCCCTTTCAGTTCTATGCTCACATATTCAAAT
ATCAAATGTAATTTAGCTGAAGTTATTTAATAATCAAGTCTTTCAATATCTGTTCAAAGAAAAAGAACACACTTTGAAAATTCTGCAAAG
CTGTCTCCCAGTCTTTAAAATGTCTGGAAGCACTCTCCTTCTTTACAATACCAACATCACTGGCCCAGAATCTTCCCTGTGCTAGTTTGT
AAATATAAATAAATTACTTGTTTTGTAAACTTTTGTAAAGAATATTTTGGTAGAAATACTTCAAACATATTCTTTGGGTTATATTTATAC
ATATGTGAAATAAATATACTATCAAAAGGTTATATTTTATACAAAAAGTAAATTGCTACCTTTTGTATGCTAATATGCAAAGTTTTGTAT
AATATGATGGTTTATTTTTAGCTCTACACTTAAACCATAGGTGGTTGAGTGGGAACTTTTGAAAACTATCAAGAGGCTTGTTAGACAAAT
TTATATTCTGAAACCTCAATAAGAAAGCATTCCAGGTTTCAATCCTTGTTTTTTGTCCTGCTCCCAAATTCTTTTTTAAACCCATAGTTC
TTGTGTCTTATTTGATTCTTCTGCTGTGCACATTGTATTGGTCCTTGTTGCATGTAGTCTACTGTGTGTTTTCCGATTTTATAAGGCAGC
ATTTCTCCATACAAAAAGAAAAAAAATGATGTACATATAAACGCTTTTGTTGTATGGCTCCTCCATGTTACTGTATATATCTGCCAGCAC
TTCCCAGTTACACTCCTGTGAGTCAGCTTATTTTTACCCTAACATAAATAGTATGTTTTGTAGTAGTTATCAAATTTAAGAGATAAAGCA
ATCAGAATGTTTGGATTTTCTTCTATCTTAATGTGAATTTCATAATTAATGTCTATTTATTCAGCTATTCATTAAAATACAGGATTCTTT
GGGAAAA

>19573_19573_6_CRTC3-MAML2_CRTC3_chr15_91073435_ENST00000420329_MAML2_chr11_95826682_ENST00000524717_length(amino acids)=1029AA_BP=44
MAASPGSGSANPRKFSEKIALHTQRQAEETRAFEQLMTDLTLSRLQGSLKRKQVVNLSPANSKRPNGFVDNSFLDIKRIRVGENLSAGQG
GLQINNGQSQIMSGTLPMSQAPLRKTNTLPSHTHSPGNGLFNMGLKEVKKEPGETLSCSKHMDGQMTQENIFPNRYGDDPGEQLMDPELQ
ELFNELTNISVPPMSDLELENMINATIKQDDPFNIDLGQQSQRSTPRPSLPMEKIVIKSEYSPGLTQGPSGSPQLRPPSAGPAFSMANSA
LSTSSPIPSVPQSQAQPQTGSGASRALPSWQEVSHAQQLKQIAANRQQHARMQQHQQQHQPTNWSALPSSAGPSPGPFGQEKIPSPSFGQ
QTFSPQSSPMPGVAGGSGQSKVMANYMYKAGPSAQGGHLDVLMQQKPQDLSRSFINNPHPAMEPRQGNTKPLFHFNSDQANQQMPSVLPS
QNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPS
SQPAQSLPSQPLLRSPLPLQQKLLLQQMQNQPIAGMGYQVSQQQRQDQHSVVGQNTGPSPSPNPCSNPNTGSGYMNSQQSLLNQQLMGKK
QTLQRQIMEQKQQLLLQQQMLADAEKIAPQDQINRHLSRPPPDYKDQRRNVGNMQPTAQYSGGSSTISLNSNQALANPVSTHTILTPNSS
LLSTSHGTRMPSLSTAVQNMGMYGNLPCNQPNTYSVTSGMNQLTQQRNPKQLLANQNNPMMPRPPTLGPSNNNNVATFGAGSVGNSQQLR
PNLTHSMASMPPQRTSNVMITSNTTAPNWASQEGTSKQQEALTSAGVRFPTGTPAAYTPNQSLQQAVGSQQFSQRAVAPPNQLTPAVQMR
PMNQMSQTLNGQTMGPLRGLNLRPNQLSTQILPNLNQSGTGLNQSRTGINQPPSLTPSNFPSPNQSSRAFQGTDHSSDLAFDFLSQQNDN
MGPALNSDADFIDSLLKTEPGNDDWMKDINLDEILGNNS

--------------------------------------------------------------
>19573_19573_7_CRTC3-MAML2_CRTC3_chr15_91073435_ENST00000560098_MAML2_chr11_95826625_ENST00000524717_length(transcript)=5488nt_BP=236nt
CTGGCTTCGGGCGGCGGCCCCGGCGGCCTGTGGACGGACGGGTGGGCCGAGGTACAGGCCCCACGGCCGCCGTCTCCCGCTTCTGCCCGC
GCAGAGTCCGCGCCATGGCCGCCTCGCCGGGCTCGGGCAGCGCCAACCCGCGGAAGTTCAGTGAGAAGATCGCGCTGCACACGCAGAGAC
AGGCCGAGGAGACGCGGGCCTTCGAGCAGCTCATGACCGACCTCACCCTGTCGCGGGTGGCTCATCCACAATAAGCTTAAACTCTAACCA
GGCTTTGGCAAACCCAGTTTCAACACACACCATTTTAACTCCCAATTCCAGCCTCCTGTCTACTTCTCACGGGACAAGAATGCCATCATT
ATCTACAGCAGTTCAGAATATGGGGATGTATGGAAATCTGCCTTGTAATCAACCTAACACATACAGTGTCACTTCAGGAATGAATCAATT
GACCCAACAGAGAAACCCAAAGCAATTGTTAGCAAATCAAAACAACCCTATGATGCCACGGCCACCTACCTTAGGGCCAAGTAATAATAA
CAATGTAGCCACTTTTGGAGCTGGATCTGTTGGTAATTCACAACAATTGAGACCAAATTTAACCCATAGTATGGCAAGCATGCCACCACA
GAGAACATCAAACGTAATGATCACATCCAACACAACTGCACCAAACTGGGCCTCTCAAGAAGGAACAAGCAAACAGCAAGAAGCCCTGAC
GTCTGCAGGAGTCCGCTTCCCCACAGGTACACCTGCAGCCTATACCCCAAATCAGTCACTGCAACAGGCAGTAGGTAGCCAGCAATTTTC
CCAGAGGGCAGTGGCTCCTCCTAACCAGTTAACACCAGCAGTGCAAATGAGACCCATGAACCAAATGAGCCAAACACTAAATGGGCAAAC
CATGGGTCCCCTCAGGGGTCTGAATCTCAGACCCAATCAGCTAAGCACACAGATTTTGCCTAATTTGAATCAGTCAGGAACAGGGTTGAA
TCAGTCGAGGACGGGCATCAACCAGCCACCATCCCTGACGCCCAGCAATTTTCCTTCACCCAACCAAAGTTCCAGGGCTTTTCAAGGAAC
TGACCACAGCAGTGACTTAGCTTTTGACTTCCTCAGCCAACAAAATGATAACATGGGCCCTGCCCTAAACAGTGATGCTGATTTCATTGA
TTCTTTATTGAAGACAGAGCCTGGTAATGATGACTGGATGAAAGACATCAATCTTGATGAAATCTTGGGGAACAATTCCTAAAGAAGAAA
GGGAAGACAATTTACAAACTCCAAGCACTAAAAGGCAGTATATTACAGAAACTCTGTAGAGGCTGAACTGTTGATGTTCAGGTGGACTAC
ATGAAGATAACATGCTTAAAAATGGAAAGCAGAAAGTAACTGCAGTGATGAACATTTTGGTCCAAATTCTTGTTTTAAATCTTACACCTG
AAAGTAAAATATTGGGATCACTTTTCCCTGTCTAAACTCCAGGATACAGTATCCAATTTATCCAAACAGAACTGTGGTGTCAATGTGTAA
TTAATTGTGTAAAATAGCCTTCCCAAGTTTCTTTTTCCCTGGAAAATAAAAAAGGTAATAGAACTTGTAGTTTATTTAAACCCCATGTCA
TGAGGAGGTACTAGTTCCAAGCAACAAACTCCTTAATTTGCTCTAATAGATAGGTATGGTTTAATCTTTCCATTGTGTCTTTTCATTTAA
TTTTCCTGAAGCTTGCAGGATAGATTGAAATGTTATAGGTTTGTTTGGAGTAACCAAACAGTATGCAAATTAAGAAAAAGCCAGAGAACC
TAGAAAACATCCAGTGGATTACAGAATTTCTTCCCCATATTCACTCCTCACTTTTACAATTTTCCCACAATCCTCTACTTCAGTGGGATG
CTGTGTCTAGTGATTAAACAAAAATATAGAGCTGTGCAATTTGATTTTGGCTTCCACAACGAATATCTGAATCCATTCCAAATGAAATTT
TAGATATAACAAAGACTTGTCCTAATCATACTGAAATATTGGTGCACACCTCTCTGCATTAGATTTCACTTTTTTAAAAAACCCAGTGGA
CATTGCTATAAATAAGATTTATTTGGCTACAAATAACCTGGGATGTTGCTTATTATGATTGATGCCTGCTGGTTTGTTCCCAAGCTGAGT
GAAATTGAACCTCGTCCTCCCTACTCATTTTGATGACTGAGGCTGGTTTATAAGAAAAGGAAGTTTGGAGAAGAAAACCGAGATTAGAAA
ATATCATGTTTTGGTTGGAGATAAGAACCAGGGATGGCAAGTACCAGTGTGTACAAATGTATTTCACGGAGTTTGAAGGAACGCATAATC
AAGAGGGAAAACAATTTGTCCTTCATTGGACGTATTATTTGGATTTGGGTGAGCAACAAAATGGAATGTGGTCTGTTAGGAGCATTCTGT
TTGTTCTTTTGTCCCTGATGTGATGAATCATTGCCACATGCTAGATGGACTCTTCATATCCAGGTTTTGTCCCTCAGGGCTGAGCACTGT
ATTAAAGAGTTTTTGTTGAGTCATTTAACCTTAGTGTCCACATCCAGATCAGCTGTAAAATGGGGAAGACGTGTGCTGATTTGGAATGAA
TGCAAAATATCACTATCATTTTCCTAATTACAGAGGAGCAAAGGTTATCTTCAGCCCTTTCAGTTCTATGCTCACATATTCAAATATCAA
ATGTAATTTAGCTGAAGTTATTTAATAATCAAGTCTTTCAATATCTGTTCAAAGAAAAAGAACACACTTTGAAAATTCTGCAAAGCTGTC
TCCCAGTCTTTAAAATGTCTGGAAGCACTCTCCTTCTTTACAATACCAACATCACTGGCCCAGAATCTTCCCTGTGCTAGTTTGTAAATA
TAAATAAATTACTTGTTTTGTAAACTTTTGTAAAGAATATTTTGGTAGAAATACTTCAAACATATTCTTTGGGTTATATTTATACATATG
TGAAATAAATATACTATCAAAAGGTTATATTTTATACAAAAAGTAAATTGCTACCTTTTGTATGCTAATATGCAAAGTTTTGTATAATAT
GATGGTTTATTTTTAGCTCTACACTTAAACCATAGGTGGTTGAGTGGGAACTTTTGAAAACTATCAAGAGGCTTGTTAGACAAATTTATA
TTCTGAAACCTCAATAAGAAAGCATTCCAGGTTTCAATCCTTGTTTTTTGTCCTGCTCCCAAATTCTTTTTTAAACCCATAGTTCTTGTG
TCTTATTTGATTCTTCTGCTGTGCACATTGTATTGGTCCTTGTTGCATGTAGTCTACTGTGTGTTTTCCGATTTTATAAGGCAGCATTTC
TCCATACAAAAAGAAAAAAAATGATGTACATATAAACGCTTTTGTTGTATGGCTCCTCCATGTTACTGTATATATCTGCCAGCACTTCCC
AGTTACACTCCTGTGAGTCAGCTTATTTTTACCCTAACATAAATAGTATGTTTTGTAGTAGTTATCAAATTTAAGAGATAAAGCAATCAG
AATGTTTGGATTTTCTTCTATCTTAATGTGAATTTCATAATTAATGTCTATTTATTCAGCTATTCATTAAAATACAGGATTCTTTGGGAA
AAGAGAAAATTGCTCCACAAGATCAGATAAACCGACATTTGTCAAGGCCACCTCCAGATTATAAAGACCAAAGAAGAAATGTGGGCAATA
TGCAACCAACTGCTCAGTATTCTGGATCAACACTCTGTGGTAGGCCAGAACACAGGCCCCAGTCCAAGTCCTAACCCCTGCTCAAATCCA
AACACTGGAAGTGGTTACATGAACTCCCAGCAATCACTGTTGAATCAGCAATTGATGGGAAAGAAGCAGACTCTACAGAGGCAGATCATG
GAGCAGAAACAGCAACTTCTTCTCCAGCAGCAGATGCTGGCTGACGCGGCGACCCAATGGCTTTGTGGACAACTCATTTCTTGATATCAA
AAGAATTCGTGTTGGGGAGAATCTCTCTGCAGGACAAGGTGGCCTCCAAATAAACAATGGACAAAGTCAGATTATGTCAGGGACCTTGCC
TATGAGCCAAGCACCCCTGCGAAAGACTAACACTCTGCCATCCCATACACATTCTCCTGGCAATGGCCTGTTTAACATGGGCTTAAAGGA
GGTAAAGAAGGAGCCAGGAGAGACTCTGTCTTGCAGTAAGCACATGGATGGCCAAATGACCCAAGAGAATATTTTTCCTAATAGGTACGG
AGACGACCCTGGAGAACAACTGATGGATCCTGAGCTGCAGGAACTGTTCAATGAACTGACCAACATATCTGTGCCTCCCATGAGTGACCT
TGAACTGGAGAACATGATCAATGCCACCATAAAGCAGGATGACCCATTTAACATTGACTTGGGTCAGCAAAGCCAGAGGAGCACACCTAG
GCCCTCCTTACCCATGGAGAAAATAGTGATCAAAAGTGAATACTCACCGGGCTTGACTCAGGGCCCCTCAGGCTCTCCTCAGCTGAGGCC
CCCATCAGCTGGCCCCGCATTCTCCATGGCCAACTCTGCCCTCTCCACTTCGTCTCCAATCCCTTCAGTCCCTCAGAGCCAGGCTCAGCC
TCAGACAGGCTCCGGAGCAAGCCGGGCCTTGCCAAGCTGGCAGGAAGTATCCCATGCCCAGCAGCTCAAACAGATAGCTGCTAATCGTCA
GCAGCATGCCCGGATGCAGCAGCACCAGCAGCAGCACCAGCCTACCAACTGGTCAGCCTTGCCCTCTTCTGCTGGACCATCACCAGGTCC
ATTTGGGCAGGAGAAAATCCCCAGCCCTTCTTTTGGTCAGCAGACATTCAGCCCACAGAGCTCCCCCATGCCTGGGGTAGCTGGCGGCAG
CGGCCAGTCGAAAGTAATGGCTAACTACATGTACAAGGCCGGCCCCTCAGCCCAGGGTGGGCACCTAGATGTCCTCATGCAGCAAAAGCC
TCAGGATCTCAGTCGAAGTTTTATTAACAACCCGCACCCAGCCATGGAGCCCCGTCAGGGCAACACCAAGCCTTTGTTTCATTTTAACTC
AGATCAAGCGAACCAGCAGATGCCTTCTGTTTTGCCTTCCCAGAACAAGCCTTCTCTCCTACACTACACCCAACAGCAACAGCAGCAACA
GCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAACAGCAGCAGCAGCAGCAACAGCAACAGCAACAGCAACAGCAGAGTTCAAT
TTCAGCTCAACAACAGCAACAGCAGCAGAGCTCAATTTCAGCCCAACAGCAGCAGCAGCAGCAACAACAGCAGCAGCAGCAGCAACAACA
ACAGCAACAACAGCAGCAGCAGCAGCAGCAACAACCATCTTCTCAGCCTGCCCAATCTCTACCAAGCCAGCCTTTGCTAAGGTCACCTTT
GCCACTTCAGCAAAAGCTCCTACTTCAGCAAATGCAGAATCAGCCCATTGCAGGAATGGGATACCAAGTCTCCCAACAACAGAGACAG

>19573_19573_7_CRTC3-MAML2_CRTC3_chr15_91073435_ENST00000560098_MAML2_chr11_95826625_ENST00000524717_length(amino acids)=526AA_BP=3
MTRRPNGFVDNSFLDIKRIRVGENLSAGQGGLQINNGQSQIMSGTLPMSQAPLRKTNTLPSHTHSPGNGLFNMGLKEVKKEPGETLSCSK
HMDGQMTQENIFPNRYGDDPGEQLMDPELQELFNELTNISVPPMSDLELENMINATIKQDDPFNIDLGQQSQRSTPRPSLPMEKIVIKSE
YSPGLTQGPSGSPQLRPPSAGPAFSMANSALSTSSPIPSVPQSQAQPQTGSGASRALPSWQEVSHAQQLKQIAANRQQHARMQQHQQQHQ
PTNWSALPSSAGPSPGPFGQEKIPSPSFGQQTFSPQSSPMPGVAGGSGQSKVMANYMYKAGPSAQGGHLDVLMQQKPQDLSRSFINNPHP
AMEPRQGNTKPLFHFNSDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSIS
AQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLLQQMQNQPIAGMGYQVSQQQRQ

--------------------------------------------------------------
>19573_19573_8_CRTC3-MAML2_CRTC3_chr15_91073435_ENST00000560098_MAML2_chr11_95826681_ENST00000524717_length(transcript)=5544nt_BP=236nt
CTGGCTTCGGGCGGCGGCCCCGGCGGCCTGTGGACGGACGGGTGGGCCGAGGTACAGGCCCCACGGCCGCCGTCTCCCGCTTCTGCCCGC
GCAGAGTCCGCGCCATGGCCGCCTCGCCGGGCTCGGGCAGCGCCAACCCGCGGAAGTTCAGTGAGAAGATCGCGCTGCACACGCAGAGAC
AGGCCGAGGAGACGCGGGCCTTCGAGCAGCTCATGACCGACCTCACCCTGTCGCGGCTCCAGGGTTCCTTGAAAAGAAAACAGGTAGTTA
ACCTATCTCCTGCCAACAGCAAGCGACCCAATGGCTTTGTGGACAACTCATTTCTTGATATCAAAAGAATTCGTGTTGGGGAGAATCTCT
CTGCAGGACAAGGTGGCCTCCAAATAAACAATGGACAAAGTCAGATTATGTCAGGGACCTTGCCTATGAGCCAAGCACCCCTGCGAAAGA
CTAACACTCTGCCATCCCATACACATTCTCCTGGCAATGGCCTGTTTAACATGGGCTTAAAGGAGGTAAAGAAGGAGCCAGGAGAGACTC
TGTCTTGCAGTAAGCACATGGATGGCCAAATGACCCAAGAGAATATTTTTCCTAATAGGTACGGAGACGACCCTGGAGAACAACTGATGG
ATCCTGAGCTGCAGGAACTGTTCAATGAACTGACCAACATATCTGTGCCTCCCATGAGTGACCTTGAACTGGAGAACATGATCAATGCCA
CCATAAAGCAGGATGACCCATTTAACATTGACTTGGGTCAGCAAAGCCAGAGGAGCACACCTAGGCCCTCCTTACCCATGGAGAAAATAG
TGATCAAAAGTGAATACTCACCGGGCTTGACTCAGGGCCCCTCAGGCTCTCCTCAGCTGAGGCCCCCATCAGCTGGCCCCGCATTCTCCA
TGGCCAACTCTGCCCTCTCCACTTCGTCTCCAATCCCTTCAGTCCCTCAGAGCCAGGCTCAGCCTCAGACAGGCTCCGGAGCAAGCCGGG
CCTTGCCAAGCTGGCAGGAAGTATCCCATGCCCAGCAGCTCAAACAGATAGCTGCTAATCGTCAGCAGCATGCCCGGATGCAGCAGCACC
AGCAGCAGCACCAGCCTACCAACTGGTCAGCCTTGCCCTCTTCTGCTGGACCATCACCAGGTCCATTTGGGCAGGAGAAAATCCCCAGCC
CTTCTTTTGGTCAGCAGACATTCAGCCCACAGAGCTCCCCCATGCCTGGGGTAGCTGGCGGCAGCGGCCAGTCGAAAGTAATGGCTAACT
ACATGTACAAGGCCGGCCCCTCAGCCCAGGGTGGGCACCTAGATGTCCTCATGCAGCAAAAGCCTCAGGATCTCAGTCGAAGTTTTATTA
ACAACCCGCACCCAGCCATGGAGCCCCGTCAGGGCAACACCAAGCCTTTGTTTCATTTTAACTCAGATCAAGCGAACCAGCAGATGCCTT
CTGTTTTGCCTTCCCAGAACAAGCCTTCTCTCCTACACTACACCCAACAGCAACAGCAGCAACAGCAGCAGCAGCAGCAGCAGCAGCAGC
AGCAGCAGCAGCAACAGCAGCAGCAGCAGCAACAGCAACAGCAACAGCAACAGCAGAGTTCAATTTCAGCTCAACAACAGCAACAGCAGC
AGAGCTCAATTTCAGCCCAACAGCAGCAGCAGCAGCAACAACAGCAGCAGCAGCAGCAACAACAACAGCAACAACAGCAGCAGCAGCAGC
AGCAACAACCATCTTCTCAGCCTGCCCAATCTCTACCAAGCCAGCCTTTGCTAAGGTCACCTTTGCCACTTCAGCAAAAGCTCCTACTTC
AGCAAATGCAGAATCAGCCCATTGCAGGAATGGGATACCAAGTCTCCCAACAACAGAGACAGGATCAACACTCTGTGGTAGGCCAGAACA
CAGGCCCCAGTCCAAGTCCTAACCCCTGCTCAAATCCAAACACTGGAAGTGGTTACATGAACTCCCAGCAATCACTGTTGAATCAGCAAT
TGATGGGAAAGAAGCAGACTCTACAGAGGCAGATCATGGAGCAGAAACAGCAACTTCTTCTCCAGCAGCAGATGCTGGCTGACGCGGAGA
AAATTGCTCCACAAGATCAGATAAACCGACATTTGTCAAGGCCACCTCCAGATTATAAAGACCAAAGAAGAAATGTGGGCAATATGCAAC
CAACTGCTCAGTATTCTGGTGGCTCATCCACAATAAGCTTAAACTCTAACCAGGCTTTGGCAAACCCAGTTTCAACACACACCATTTTAA
CTCCCAATTCCAGCCTCCTGTCTACTTCTCACGGGACAAGAATGCCATCATTATCTACAGCAGTTCAGAATATGGGGATGTATGGAAATC
TGCCTTGTAATCAACCTAACACATACAGTGTCACTTCAGGAATGAATCAATTGACCCAACAGAGAAACCCAAAGCAATTGTTAGCAAATC
AAAACAACCCTATGATGCCACGGCCACCTACCTTAGGGCCAAGTAATAATAACAATGTAGCCACTTTTGGAGCTGGATCTGTTGGTAATT
CACAACAATTGAGACCAAATTTAACCCATAGTATGGCAAGCATGCCACCACAGAGAACATCAAACGTAATGATCACATCCAACACAACTG
CACCAAACTGGGCCTCTCAAGAAGGAACAAGCAAACAGCAAGAAGCCCTGACGTCTGCAGGAGTCCGCTTCCCCACAGGTACACCTGCAG
CCTATACCCCAAATCAGTCACTGCAACAGGCAGTAGGTAGCCAGCAATTTTCCCAGAGGGCAGTGGCTCCTCCTAACCAGTTAACACCAG
CAGTGCAAATGAGACCCATGAACCAAATGAGCCAAACACTAAATGGGCAAACCATGGGTCCCCTCAGGGGTCTGAATCTCAGACCCAATC
AGCTAAGCACACAGATTTTGCCTAATTTGAATCAGTCAGGAACAGGGTTGAATCAGTCGAGGACGGGCATCAACCAGCCACCATCCCTGA
CGCCCAGCAATTTTCCTTCACCCAACCAAAGTTCCAGGGCTTTTCAAGGAACTGACCACAGCAGTGACTTAGCTTTTGACTTCCTCAGCC
AACAAAATGATAACATGGGCCCTGCCCTAAACAGTGATGCTGATTTCATTGATTCTTTATTGAAGACAGAGCCTGGTAATGATGACTGGA
TGAAAGACATCAATCTTGATGAAATCTTGGGGAACAATTCCTAAAGAAGAAAGGGAAGACAATTTACAAACTCCAAGCACTAAAAGGCAG
TATATTACAGAAACTCTGTAGAGGCTGAACTGTTGATGTTCAGGTGGACTACATGAAGATAACATGCTTAAAAATGGAAAGCAGAAAGTA
ACTGCAGTGATGAACATTTTGGTCCAAATTCTTGTTTTAAATCTTACACCTGAAAGTAAAATATTGGGATCACTTTTCCCTGTCTAAACT
CCAGGATACAGTATCCAATTTATCCAAACAGAACTGTGGTGTCAATGTGTAATTAATTGTGTAAAATAGCCTTCCCAAGTTTCTTTTTCC
CTGGAAAATAAAAAAGGTAATAGAACTTGTAGTTTATTTAAACCCCATGTCATGAGGAGGTACTAGTTCCAAGCAACAAACTCCTTAATT
TGCTCTAATAGATAGGTATGGTTTAATCTTTCCATTGTGTCTTTTCATTTAATTTTCCTGAAGCTTGCAGGATAGATTGAAATGTTATAG
GTTTGTTTGGAGTAACCAAACAGTATGCAAATTAAGAAAAAGCCAGAGAACCTAGAAAACATCCAGTGGATTACAGAATTTCTTCCCCAT
ATTCACTCCTCACTTTTACAATTTTCCCACAATCCTCTACTTCAGTGGGATGCTGTGTCTAGTGATTAAACAAAAATATAGAGCTGTGCA
ATTTGATTTTGGCTTCCACAACGAATATCTGAATCCATTCCAAATGAAATTTTAGATATAACAAAGACTTGTCCTAATCATACTGAAATA
TTGGTGCACACCTCTCTGCATTAGATTTCACTTTTTTAAAAAACCCAGTGGACATTGCTATAAATAAGATTTATTTGGCTACAAATAACC
TGGGATGTTGCTTATTATGATTGATGCCTGCTGGTTTGTTCCCAAGCTGAGTGAAATTGAACCTCGTCCTCCCTACTCATTTTGATGACT
GAGGCTGGTTTATAAGAAAAGGAAGTTTGGAGAAGAAAACCGAGATTAGAAAATATCATGTTTTGGTTGGAGATAAGAACCAGGGATGGC
AAGTACCAGTGTGTACAAATGTATTTCACGGAGTTTGAAGGAACGCATAATCAAGAGGGAAAACAATTTGTCCTTCATTGGACGTATTAT
TTGGATTTGGGTGAGCAACAAAATGGAATGTGGTCTGTTAGGAGCATTCTGTTTGTTCTTTTGTCCCTGATGTGATGAATCATTGCCACA
TGCTAGATGGACTCTTCATATCCAGGTTTTGTCCCTCAGGGCTGAGCACTGTATTAAAGAGTTTTTGTTGAGTCATTTAACCTTAGTGTC
CACATCCAGATCAGCTGTAAAATGGGGAAGACGTGTGCTGATTTGGAATGAATGCAAAATATCACTATCATTTTCCTAATTACAGAGGAG
CAAAGGTTATCTTCAGCCCTTTCAGTTCTATGCTCACATATTCAAATATCAAATGTAATTTAGCTGAAGTTATTTAATAATCAAGTCTTT
CAATATCTGTTCAAAGAAAAAGAACACACTTTGAAAATTCTGCAAAGCTGTCTCCCAGTCTTTAAAATGTCTGGAAGCACTCTCCTTCTT
TACAATACCAACATCACTGGCCCAGAATCTTCCCTGTGCTAGTTTGTAAATATAAATAAATTACTTGTTTTGTAAACTTTTGTAAAGAAT
ATTTTGGTAGAAATACTTCAAACATATTCTTTGGGTTATATTTATACATATGTGAAATAAATATACTATCAAAAGGTTATATTTTATACA
AAAAGTAAATTGCTACCTTTTGTATGCTAATATGCAAAGTTTTGTATAATATGATGGTTTATTTTTAGCTCTACACTTAAACCATAGGTG
GTTGAGTGGGAACTTTTGAAAACTATCAAGAGGCTTGTTAGACAAATTTATATTCTGAAACCTCAATAAGAAAGCATTCCAGGTTTCAAT
CCTTGTTTTTTGTCCTGCTCCCAAATTCTTTTTTAAACCCATAGTTCTTGTGTCTTATTTGATTCTTCTGCTGTGCACATTGTATTGGTC
CTTGTTGCATGTAGTCTACTGTGTGTTTTCCGATTTTATAAGGCAGCATTTCTCCATACAAAAAGAAAAAAAATGATGTACATATAAACG
CTTTTGTTGTATGGCTCCTCCATGTTACTGTATATATCTGCCAGCACTTCCCAGTTACACTCCTGTGAGTCAGCTTATTTTTACCCTAAC
ATAAATAGTATGTTTTGTAGTAGTTATCAAATTTAAGAGATAAAGCAATCAGAATGTTTGGATTTTCTTCTATCTTAATGTGAATTTCAT
AATTAATGTCTATTTATTCAGCTATTCATTAAAATACAGGATTCTTTGGGAAAA

>19573_19573_8_CRTC3-MAML2_CRTC3_chr15_91073435_ENST00000560098_MAML2_chr11_95826681_ENST00000524717_length(amino acids)=1029AA_BP=44
MAASPGSGSANPRKFSEKIALHTQRQAEETRAFEQLMTDLTLSRLQGSLKRKQVVNLSPANSKRPNGFVDNSFLDIKRIRVGENLSAGQG
GLQINNGQSQIMSGTLPMSQAPLRKTNTLPSHTHSPGNGLFNMGLKEVKKEPGETLSCSKHMDGQMTQENIFPNRYGDDPGEQLMDPELQ
ELFNELTNISVPPMSDLELENMINATIKQDDPFNIDLGQQSQRSTPRPSLPMEKIVIKSEYSPGLTQGPSGSPQLRPPSAGPAFSMANSA
LSTSSPIPSVPQSQAQPQTGSGASRALPSWQEVSHAQQLKQIAANRQQHARMQQHQQQHQPTNWSALPSSAGPSPGPFGQEKIPSPSFGQ
QTFSPQSSPMPGVAGGSGQSKVMANYMYKAGPSAQGGHLDVLMQQKPQDLSRSFINNPHPAMEPRQGNTKPLFHFNSDQANQQMPSVLPS
QNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPS
SQPAQSLPSQPLLRSPLPLQQKLLLQQMQNQPIAGMGYQVSQQQRQDQHSVVGQNTGPSPSPNPCSNPNTGSGYMNSQQSLLNQQLMGKK
QTLQRQIMEQKQQLLLQQQMLADAEKIAPQDQINRHLSRPPPDYKDQRRNVGNMQPTAQYSGGSSTISLNSNQALANPVSTHTILTPNSS
LLSTSHGTRMPSLSTAVQNMGMYGNLPCNQPNTYSVTSGMNQLTQQRNPKQLLANQNNPMMPRPPTLGPSNNNNVATFGAGSVGNSQQLR
PNLTHSMASMPPQRTSNVMITSNTTAPNWASQEGTSKQQEALTSAGVRFPTGTPAAYTPNQSLQQAVGSQQFSQRAVAPPNQLTPAVQMR
PMNQMSQTLNGQTMGPLRGLNLRPNQLSTQILPNLNQSGTGLNQSRTGINQPPSLTPSNFPSPNQSSRAFQGTDHSSDLAFDFLSQQNDN
MGPALNSDADFIDSLLKTEPGNDDWMKDINLDEILGNNS

--------------------------------------------------------------
>19573_19573_9_CRTC3-MAML2_CRTC3_chr15_91073435_ENST00000560098_MAML2_chr11_95826682_ENST00000524717_length(transcript)=5544nt_BP=236nt
CTGGCTTCGGGCGGCGGCCCCGGCGGCCTGTGGACGGACGGGTGGGCCGAGGTACAGGCCCCACGGCCGCCGTCTCCCGCTTCTGCCCGC
GCAGAGTCCGCGCCATGGCCGCCTCGCCGGGCTCGGGCAGCGCCAACCCGCGGAAGTTCAGTGAGAAGATCGCGCTGCACACGCAGAGAC
AGGCCGAGGAGACGCGGGCCTTCGAGCAGCTCATGACCGACCTCACCCTGTCGCGGCTCCAGGGTTCCTTGAAAAGAAAACAGGTAGTTA
ACCTATCTCCTGCCAACAGCAAGCGACCCAATGGCTTTGTGGACAACTCATTTCTTGATATCAAAAGAATTCGTGTTGGGGAGAATCTCT
CTGCAGGACAAGGTGGCCTCCAAATAAACAATGGACAAAGTCAGATTATGTCAGGGACCTTGCCTATGAGCCAAGCACCCCTGCGAAAGA
CTAACACTCTGCCATCCCATACACATTCTCCTGGCAATGGCCTGTTTAACATGGGCTTAAAGGAGGTAAAGAAGGAGCCAGGAGAGACTC
TGTCTTGCAGTAAGCACATGGATGGCCAAATGACCCAAGAGAATATTTTTCCTAATAGGTACGGAGACGACCCTGGAGAACAACTGATGG
ATCCTGAGCTGCAGGAACTGTTCAATGAACTGACCAACATATCTGTGCCTCCCATGAGTGACCTTGAACTGGAGAACATGATCAATGCCA
CCATAAAGCAGGATGACCCATTTAACATTGACTTGGGTCAGCAAAGCCAGAGGAGCACACCTAGGCCCTCCTTACCCATGGAGAAAATAG
TGATCAAAAGTGAATACTCACCGGGCTTGACTCAGGGCCCCTCAGGCTCTCCTCAGCTGAGGCCCCCATCAGCTGGCCCCGCATTCTCCA
TGGCCAACTCTGCCCTCTCCACTTCGTCTCCAATCCCTTCAGTCCCTCAGAGCCAGGCTCAGCCTCAGACAGGCTCCGGAGCAAGCCGGG
CCTTGCCAAGCTGGCAGGAAGTATCCCATGCCCAGCAGCTCAAACAGATAGCTGCTAATCGTCAGCAGCATGCCCGGATGCAGCAGCACC
AGCAGCAGCACCAGCCTACCAACTGGTCAGCCTTGCCCTCTTCTGCTGGACCATCACCAGGTCCATTTGGGCAGGAGAAAATCCCCAGCC
CTTCTTTTGGTCAGCAGACATTCAGCCCACAGAGCTCCCCCATGCCTGGGGTAGCTGGCGGCAGCGGCCAGTCGAAAGTAATGGCTAACT
ACATGTACAAGGCCGGCCCCTCAGCCCAGGGTGGGCACCTAGATGTCCTCATGCAGCAAAAGCCTCAGGATCTCAGTCGAAGTTTTATTA
ACAACCCGCACCCAGCCATGGAGCCCCGTCAGGGCAACACCAAGCCTTTGTTTCATTTTAACTCAGATCAAGCGAACCAGCAGATGCCTT
CTGTTTTGCCTTCCCAGAACAAGCCTTCTCTCCTACACTACACCCAACAGCAACAGCAGCAACAGCAGCAGCAGCAGCAGCAGCAGCAGC
AGCAGCAGCAGCAACAGCAGCAGCAGCAGCAACAGCAACAGCAACAGCAACAGCAGAGTTCAATTTCAGCTCAACAACAGCAACAGCAGC
AGAGCTCAATTTCAGCCCAACAGCAGCAGCAGCAGCAACAACAGCAGCAGCAGCAGCAACAACAACAGCAACAACAGCAGCAGCAGCAGC
AGCAACAACCATCTTCTCAGCCTGCCCAATCTCTACCAAGCCAGCCTTTGCTAAGGTCACCTTTGCCACTTCAGCAAAAGCTCCTACTTC
AGCAAATGCAGAATCAGCCCATTGCAGGAATGGGATACCAAGTCTCCCAACAACAGAGACAGGATCAACACTCTGTGGTAGGCCAGAACA
CAGGCCCCAGTCCAAGTCCTAACCCCTGCTCAAATCCAAACACTGGAAGTGGTTACATGAACTCCCAGCAATCACTGTTGAATCAGCAAT
TGATGGGAAAGAAGCAGACTCTACAGAGGCAGATCATGGAGCAGAAACAGCAACTTCTTCTCCAGCAGCAGATGCTGGCTGACGCGGAGA
AAATTGCTCCACAAGATCAGATAAACCGACATTTGTCAAGGCCACCTCCAGATTATAAAGACCAAAGAAGAAATGTGGGCAATATGCAAC
CAACTGCTCAGTATTCTGGTGGCTCATCCACAATAAGCTTAAACTCTAACCAGGCTTTGGCAAACCCAGTTTCAACACACACCATTTTAA
CTCCCAATTCCAGCCTCCTGTCTACTTCTCACGGGACAAGAATGCCATCATTATCTACAGCAGTTCAGAATATGGGGATGTATGGAAATC
TGCCTTGTAATCAACCTAACACATACAGTGTCACTTCAGGAATGAATCAATTGACCCAACAGAGAAACCCAAAGCAATTGTTAGCAAATC
AAAACAACCCTATGATGCCACGGCCACCTACCTTAGGGCCAAGTAATAATAACAATGTAGCCACTTTTGGAGCTGGATCTGTTGGTAATT
CACAACAATTGAGACCAAATTTAACCCATAGTATGGCAAGCATGCCACCACAGAGAACATCAAACGTAATGATCACATCCAACACAACTG
CACCAAACTGGGCCTCTCAAGAAGGAACAAGCAAACAGCAAGAAGCCCTGACGTCTGCAGGAGTCCGCTTCCCCACAGGTACACCTGCAG
CCTATACCCCAAATCAGTCACTGCAACAGGCAGTAGGTAGCCAGCAATTTTCCCAGAGGGCAGTGGCTCCTCCTAACCAGTTAACACCAG
CAGTGCAAATGAGACCCATGAACCAAATGAGCCAAACACTAAATGGGCAAACCATGGGTCCCCTCAGGGGTCTGAATCTCAGACCCAATC
AGCTAAGCACACAGATTTTGCCTAATTTGAATCAGTCAGGAACAGGGTTGAATCAGTCGAGGACGGGCATCAACCAGCCACCATCCCTGA
CGCCCAGCAATTTTCCTTCACCCAACCAAAGTTCCAGGGCTTTTCAAGGAACTGACCACAGCAGTGACTTAGCTTTTGACTTCCTCAGCC
AACAAAATGATAACATGGGCCCTGCCCTAAACAGTGATGCTGATTTCATTGATTCTTTATTGAAGACAGAGCCTGGTAATGATGACTGGA
TGAAAGACATCAATCTTGATGAAATCTTGGGGAACAATTCCTAAAGAAGAAAGGGAAGACAATTTACAAACTCCAAGCACTAAAAGGCAG
TATATTACAGAAACTCTGTAGAGGCTGAACTGTTGATGTTCAGGTGGACTACATGAAGATAACATGCTTAAAAATGGAAAGCAGAAAGTA
ACTGCAGTGATGAACATTTTGGTCCAAATTCTTGTTTTAAATCTTACACCTGAAAGTAAAATATTGGGATCACTTTTCCCTGTCTAAACT
CCAGGATACAGTATCCAATTTATCCAAACAGAACTGTGGTGTCAATGTGTAATTAATTGTGTAAAATAGCCTTCCCAAGTTTCTTTTTCC
CTGGAAAATAAAAAAGGTAATAGAACTTGTAGTTTATTTAAACCCCATGTCATGAGGAGGTACTAGTTCCAAGCAACAAACTCCTTAATT
TGCTCTAATAGATAGGTATGGTTTAATCTTTCCATTGTGTCTTTTCATTTAATTTTCCTGAAGCTTGCAGGATAGATTGAAATGTTATAG
GTTTGTTTGGAGTAACCAAACAGTATGCAAATTAAGAAAAAGCCAGAGAACCTAGAAAACATCCAGTGGATTACAGAATTTCTTCCCCAT
ATTCACTCCTCACTTTTACAATTTTCCCACAATCCTCTACTTCAGTGGGATGCTGTGTCTAGTGATTAAACAAAAATATAGAGCTGTGCA
ATTTGATTTTGGCTTCCACAACGAATATCTGAATCCATTCCAAATGAAATTTTAGATATAACAAAGACTTGTCCTAATCATACTGAAATA
TTGGTGCACACCTCTCTGCATTAGATTTCACTTTTTTAAAAAACCCAGTGGACATTGCTATAAATAAGATTTATTTGGCTACAAATAACC
TGGGATGTTGCTTATTATGATTGATGCCTGCTGGTTTGTTCCCAAGCTGAGTGAAATTGAACCTCGTCCTCCCTACTCATTTTGATGACT
GAGGCTGGTTTATAAGAAAAGGAAGTTTGGAGAAGAAAACCGAGATTAGAAAATATCATGTTTTGGTTGGAGATAAGAACCAGGGATGGC
AAGTACCAGTGTGTACAAATGTATTTCACGGAGTTTGAAGGAACGCATAATCAAGAGGGAAAACAATTTGTCCTTCATTGGACGTATTAT
TTGGATTTGGGTGAGCAACAAAATGGAATGTGGTCTGTTAGGAGCATTCTGTTTGTTCTTTTGTCCCTGATGTGATGAATCATTGCCACA
TGCTAGATGGACTCTTCATATCCAGGTTTTGTCCCTCAGGGCTGAGCACTGTATTAAAGAGTTTTTGTTGAGTCATTTAACCTTAGTGTC
CACATCCAGATCAGCTGTAAAATGGGGAAGACGTGTGCTGATTTGGAATGAATGCAAAATATCACTATCATTTTCCTAATTACAGAGGAG
CAAAGGTTATCTTCAGCCCTTTCAGTTCTATGCTCACATATTCAAATATCAAATGTAATTTAGCTGAAGTTATTTAATAATCAAGTCTTT
CAATATCTGTTCAAAGAAAAAGAACACACTTTGAAAATTCTGCAAAGCTGTCTCCCAGTCTTTAAAATGTCTGGAAGCACTCTCCTTCTT
TACAATACCAACATCACTGGCCCAGAATCTTCCCTGTGCTAGTTTGTAAATATAAATAAATTACTTGTTTTGTAAACTTTTGTAAAGAAT
ATTTTGGTAGAAATACTTCAAACATATTCTTTGGGTTATATTTATACATATGTGAAATAAATATACTATCAAAAGGTTATATTTTATACA
AAAAGTAAATTGCTACCTTTTGTATGCTAATATGCAAAGTTTTGTATAATATGATGGTTTATTTTTAGCTCTACACTTAAACCATAGGTG
GTTGAGTGGGAACTTTTGAAAACTATCAAGAGGCTTGTTAGACAAATTTATATTCTGAAACCTCAATAAGAAAGCATTCCAGGTTTCAAT
CCTTGTTTTTTGTCCTGCTCCCAAATTCTTTTTTAAACCCATAGTTCTTGTGTCTTATTTGATTCTTCTGCTGTGCACATTGTATTGGTC
CTTGTTGCATGTAGTCTACTGTGTGTTTTCCGATTTTATAAGGCAGCATTTCTCCATACAAAAAGAAAAAAAATGATGTACATATAAACG
CTTTTGTTGTATGGCTCCTCCATGTTACTGTATATATCTGCCAGCACTTCCCAGTTACACTCCTGTGAGTCAGCTTATTTTTACCCTAAC
ATAAATAGTATGTTTTGTAGTAGTTATCAAATTTAAGAGATAAAGCAATCAGAATGTTTGGATTTTCTTCTATCTTAATGTGAATTTCAT
AATTAATGTCTATTTATTCAGCTATTCATTAAAATACAGGATTCTTTGGGAAAA

>19573_19573_9_CRTC3-MAML2_CRTC3_chr15_91073435_ENST00000560098_MAML2_chr11_95826682_ENST00000524717_length(amino acids)=1029AA_BP=44
MAASPGSGSANPRKFSEKIALHTQRQAEETRAFEQLMTDLTLSRLQGSLKRKQVVNLSPANSKRPNGFVDNSFLDIKRIRVGENLSAGQG
GLQINNGQSQIMSGTLPMSQAPLRKTNTLPSHTHSPGNGLFNMGLKEVKKEPGETLSCSKHMDGQMTQENIFPNRYGDDPGEQLMDPELQ
ELFNELTNISVPPMSDLELENMINATIKQDDPFNIDLGQQSQRSTPRPSLPMEKIVIKSEYSPGLTQGPSGSPQLRPPSAGPAFSMANSA
LSTSSPIPSVPQSQAQPQTGSGASRALPSWQEVSHAQQLKQIAANRQQHARMQQHQQQHQPTNWSALPSSAGPSPGPFGQEKIPSPSFGQ
QTFSPQSSPMPGVAGGSGQSKVMANYMYKAGPSAQGGHLDVLMQQKPQDLSRSFINNPHPAMEPRQGNTKPLFHFNSDQANQQMPSVLPS
QNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPS
SQPAQSLPSQPLLRSPLPLQQKLLLQQMQNQPIAGMGYQVSQQQRQDQHSVVGQNTGPSPSPNPCSNPNTGSGYMNSQQSLLNQQLMGKK
QTLQRQIMEQKQQLLLQQQMLADAEKIAPQDQINRHLSRPPPDYKDQRRNVGNMQPTAQYSGGSSTISLNSNQALANPVSTHTILTPNSS
LLSTSHGTRMPSLSTAVQNMGMYGNLPCNQPNTYSVTSGMNQLTQQRNPKQLLANQNNPMMPRPPTLGPSNNNNVATFGAGSVGNSQQLR
PNLTHSMASMPPQRTSNVMITSNTTAPNWASQEGTSKQQEALTSAGVRFPTGTPAAYTPNQSLQQAVGSQQFSQRAVAPPNQLTPAVQMR
PMNQMSQTLNGQTMGPLRGLNLRPNQLSTQILPNLNQSGTGLNQSRTGINQPPSLTPSNFPSPNQSSRAFQGTDHSSDLAFDFLSQQNDN
MGPALNSDADFIDSLLKTEPGNDDWMKDINLDEILGNNS

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Fusion Gene PPI Analysis for CRTC3-MAML2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CRTC3-MAML2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CRTC3-MAML2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneC0087031Juvenile-Onset Still Disease1CTD_human
TgeneC3495559Juvenile arthritis1CTD_human
TgeneC3714758Juvenile psoriatic arthritis1CTD_human
TgeneC4552091Polyarthritis, Juvenile, Rheumatoid Factor Negative1CTD_human
TgeneC4704862Polyarthritis, Juvenile, Rheumatoid Factor Positive1CTD_human