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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:BRD9-TPPP (FusionGDB2 ID:HG65980TG11076)

Fusion Gene Summary for BRD9-TPPP

check button Fusion gene summary
Fusion gene informationFusion gene name: BRD9-TPPP
Fusion gene ID: hg65980tg11076
HgeneTgene
Gene symbol

BRD9

TPPP

Gene ID

65980

11076

Gene namebromodomain containing 9tubulin polymerization promoting protein
SynonymsLAVS3040|PRO9856TPPP/p25|TPPP1|p24|p25|p25alpha
Cytomap('BRD9')('TPPP')

5p15.33

5p15.33

Type of geneprotein-codingprotein-coding
Descriptionbromodomain-containing protein 9rhabdomyosarcoma antigen MU-RMS-40.8sarcoma antigen NY-SAR-29tubulin polymerization-promoting protein25 kDa brain-specific proteinbrain specific protein p25 alphaglycogen synthase kinase 3 (GSK3) inhibitor p24p25-alpha
Modification date2020031520200322
UniProtAcc

Q9H8M2

.
Ensembl transtripts involved in fusion geneENST00000494422, ENST00000435709, 
ENST00000323510, ENST00000388890, 
ENST00000467963, ENST00000483173, 
ENST00000323510, ENST00000388890, 
ENST00000435709, ENST00000467963, 
ENST00000483173, ENST00000494422, 
Fusion gene scores* DoF score10 X 15 X 7=10504 X 2 X 3=24
# samples 125
** MAII scorelog2(12/1050*10)=-3.12928301694497
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(5/24*10)=1.05889368905357
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: BRD9 [Title/Abstract] AND TPPP [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointBRD9(886707)-TPPP(666238), # samples:2
Anticipated loss of major functional domain due to fusion event.BRD9-TPPP seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
BRD9-TPPP seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
BRD9-TPPP seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
BRD9-TPPP seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
BRD9-TPPP seems lost the major protein functional domain in Hgene partner, which is a epigenetic factor due to the frame-shifted ORF.
BRD9-TPPP seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
BRD9-TPPP seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneTPPP

GO:0001578

microtubule bundle formation

17105200|26289831

TgeneTPPP

GO:0030953

astral microtubule organization

22328514

TgeneTPPP

GO:0032273

positive regulation of protein polymerization

15590652

TgeneTPPP

GO:0046785

microtubule polymerization

18028908

TgeneTPPP

GO:0051418

microtubule nucleation by microtubule organizing center

31522887

TgeneTPPP

GO:0070507

regulation of microtubule cytoskeleton organization

23093407

TgeneTPPP

GO:1904428

negative regulation of tubulin deacetylation

20308065|23093407


check buttonFusion gene breakpoints across BRD9 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across TPPP (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUADTCGA-83-5908-01ABRD9chr5

886707

-TPPPchr5

666238

-
ChimerDB4LUADTCGA-83-5908BRD9chr5

886706

-TPPPchr5

666238

-


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Fusion Gene ORF analysis for BRD9-TPPP

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5UTR-3CDSENST00000494422ENST00000360578BRD9chr5

886707

-TPPPchr5

666238

-
5UTR-3CDSENST00000494422ENST00000360578BRD9chr5

886706

-TPPPchr5

666238

-
Frame-shiftENST00000435709ENST00000360578BRD9chr5

886707

-TPPPchr5

666238

-
Frame-shiftENST00000435709ENST00000360578BRD9chr5

886706

-TPPPchr5

666238

-
In-frameENST00000323510ENST00000360578BRD9chr5

886707

-TPPPchr5

666238

-
In-frameENST00000323510ENST00000360578BRD9chr5

886706

-TPPPchr5

666238

-
In-frameENST00000388890ENST00000360578BRD9chr5

886707

-TPPPchr5

666238

-
In-frameENST00000388890ENST00000360578BRD9chr5

886706

-TPPPchr5

666238

-
In-frameENST00000467963ENST00000360578BRD9chr5

886707

-TPPPchr5

666238

-
In-frameENST00000467963ENST00000360578BRD9chr5

886706

-TPPPchr5

666238

-
In-frameENST00000483173ENST00000360578BRD9chr5

886707

-TPPPchr5

666238

-
In-frameENST00000483173ENST00000360578BRD9chr5

886706

-TPPPchr5

666238

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000388890BRD9chr5886707-ENST00000360578TPPPchr5666238-51684850833277
ENST00000323510BRD9chr5886707-ENST00000360578TPPPchr5666238-52285450893297
ENST00000483173BRD9chr5886707-ENST00000360578TPPPchr5666238-54978141041162352
ENST00000467963BRD9chr5886707-ENST00000360578TPPPchr5666238-568310001671348393
ENST00000388890BRD9chr5886706-ENST00000360578TPPPchr5666238-51684850833277
ENST00000323510BRD9chr5886706-ENST00000360578TPPPchr5666238-52285450893297
ENST00000483173BRD9chr5886706-ENST00000360578TPPPchr5666238-54978141041162352
ENST00000467963BRD9chr5886706-ENST00000360578TPPPchr5666238-568310001671348393

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000388890ENST00000360578BRD9chr5886707-TPPPchr5666238-0.003702770.9962972
ENST00000323510ENST00000360578BRD9chr5886707-TPPPchr5666238-0.002782830.9972172
ENST00000483173ENST00000360578BRD9chr5886707-TPPPchr5666238-0.0248953850.9751047
ENST00000467963ENST00000360578BRD9chr5886707-TPPPchr5666238-0.0028335310.99716645
ENST00000388890ENST00000360578BRD9chr5886706-TPPPchr5666238-0.003702770.9962972
ENST00000323510ENST00000360578BRD9chr5886706-TPPPchr5666238-0.002782830.9972172
ENST00000483173ENST00000360578BRD9chr5886706-TPPPchr5666238-0.0248953850.9751047
ENST00000467963ENST00000360578BRD9chr5886706-TPPPchr5666238-0.0028335310.99716645

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Fusion Genomic Features for BRD9-TPPP


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for BRD9-TPPP


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr5:886707/chr5:666238)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
BRD9

Q9H8M2

.
FUNCTION: Plays a role in chromatin remodeling and regulation of transcription (PubMed:22464331, PubMed:26365797). Acts as a chromatin reader that recognizes and binds acylated histones: binds histones that are acetylated and/or butyrylated (PubMed:26365797). Component of SWI/SNF chromatin remodeling subcomplex GBAF that carries out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner (PubMed:29374058). Orchestrates also the RAD51-RAD54 complex formation and thereby plays a role in homologous recombination (HR) (PubMed:32457312). {ECO:0000269|PubMed:22464331, ECO:0000269|PubMed:26365797, ECO:0000269|PubMed:29374058, ECO:0000269|PubMed:32457312}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneBRD9chr5:886706chr5:666238ENST00000323510-41364_95181502.0Compositional biasNote=Lys-rich
HgeneBRD9chr5:886706chr5:666238ENST00000388890-41364_95161482.0Compositional biasNote=Lys-rich
HgeneBRD9chr5:886706chr5:666238ENST00000467963-71664_95277598.0Compositional biasNote=Lys-rich
HgeneBRD9chr5:886706chr5:666238ENST00000483173-71664_95224545.0Compositional biasNote=Lys-rich
HgeneBRD9chr5:886707chr5:666238ENST00000323510-41364_95181502.0Compositional biasNote=Lys-rich
HgeneBRD9chr5:886707chr5:666238ENST00000388890-41364_95161482.0Compositional biasNote=Lys-rich
HgeneBRD9chr5:886707chr5:666238ENST00000467963-71664_95277598.0Compositional biasNote=Lys-rich
HgeneBRD9chr5:886707chr5:666238ENST00000483173-71664_95224545.0Compositional biasNote=Lys-rich
HgeneBRD9chr5:886706chr5:666238ENST00000467963-716153_223277598.0DomainBromo
HgeneBRD9chr5:886706chr5:666238ENST00000483173-716153_223224545.0DomainBromo
HgeneBRD9chr5:886707chr5:666238ENST00000467963-716153_223277598.0DomainBromo
HgeneBRD9chr5:886707chr5:666238ENST00000483173-716153_223224545.0DomainBromo
HgeneBRD9chr5:886706chr5:666238ENST00000467963-716214_216277598.0RegionHistone H4K5ac H4K8ac and histone H4K5bu H4K8bu binding
HgeneBRD9chr5:886706chr5:666238ENST00000483173-716214_216224545.0RegionHistone H4K5ac H4K8ac and histone H4K5bu H4K8bu binding
HgeneBRD9chr5:886707chr5:666238ENST00000467963-716214_216277598.0RegionHistone H4K5ac H4K8ac and histone H4K5bu H4K8bu binding
HgeneBRD9chr5:886707chr5:666238ENST00000483173-716214_216224545.0RegionHistone H4K5ac H4K8ac and histone H4K5bu H4K8bu binding
TgeneTPPPchr5:886706chr5:666238ENST0000036057814171_192103220.0RegionDisordered
TgeneTPPPchr5:886707chr5:666238ENST0000036057814171_192103220.0RegionDisordered

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneBRD9chr5:886706chr5:666238ENST00000323510-413153_223181502.0DomainBromo
HgeneBRD9chr5:886706chr5:666238ENST00000388890-413153_223161482.0DomainBromo
HgeneBRD9chr5:886707chr5:666238ENST00000323510-413153_223181502.0DomainBromo
HgeneBRD9chr5:886707chr5:666238ENST00000388890-413153_223161482.0DomainBromo
HgeneBRD9chr5:886706chr5:666238ENST00000323510-413214_216181502.0RegionHistone H4K5ac H4K8ac and histone H4K5bu H4K8bu binding
HgeneBRD9chr5:886706chr5:666238ENST00000388890-413214_216161482.0RegionHistone H4K5ac H4K8ac and histone H4K5bu H4K8bu binding
HgeneBRD9chr5:886707chr5:666238ENST00000323510-413214_216181502.0RegionHistone H4K5ac H4K8ac and histone H4K5bu H4K8bu binding
HgeneBRD9chr5:886707chr5:666238ENST00000388890-413214_216161482.0RegionHistone H4K5ac H4K8ac and histone H4K5bu H4K8bu binding
TgeneTPPPchr5:886706chr5:666238ENST00000360578141_46103220.0RegionDisordered
TgeneTPPPchr5:886707chr5:666238ENST00000360578141_46103220.0RegionDisordered


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Fusion Gene Sequence for BRD9-TPPP


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>10230_10230_1_BRD9-TPPP_BRD9_chr5_886706_ENST00000323510_TPPP_chr5_666238_ENST00000360578_length(transcript)=5228nt_BP=545nt
ATGAAGGGATACCAAAGTCTTGTATTCAATTTTTTTTTCCTTAAATTGTCAGCCGAAAATGAGAGCACACCTATTCAGCAACTCCTGGAA
CACTTCCTCCGCCAGCTTCAGAGAAAAGATCCCCATGGATTTTTTGCTTTTCCTGTCACGGATGCAATTGCTCCTGGATATTCAATGATA
ATAAAACATCCCATGGATTTTGGCACCATGAAAGACAAAATTGTAGCTAATGAATACAAGTCAGTTACGGAATTTAAGGCAGATTTCAAG
CTGATGTGTGATAATGCAATGACATACAATAGGCCAGATACCGTGTACTACAAGTTGGCGAAGAAGATCCTTCACGCAGGCTTTAAGATG
ATGAGCAAAGAGCGGCTGTTAGCTTTGAAGCGCAGCATGTCGTTTATGCAGGACATGGATTTTTCTCAGCAGGCAGCTCTTTTGGGCAAT
GAAGATACAGCTGTTGAGGAACCTGTCCCTGAAGTTGTACCAGTACAAGTAGAAACTGCCAAGAAATCCAAAAAGCCGAGTAGAGAAGTT
ATCAGAGGGAAGTCTTGCCGGACCATCACCTTTGAGCAGTTCCAGGAGGCGCTGGAGGAGCTCGCCAAGAAGCGATTCAAAGACAAGAGC
AGCGAGGAGGCCGTTCGCGAGGTGCACAGGCTCATCGAGGGCAAGGCGCCCATCATCTCAGGGGTGACGAAAGCCATCTCGTCGCCCACA
GTGTCGAGGCTCACGGACACCACCAAGTTCACGGGCTCCCACAAGGAGCGCTTCGACCCCTCTGGCAAGGGCAAGGGCAAGGCTGGCCGC
GTGGATCTGGTGGACGAGTCAGGCTATGTGTCCGGCTACAAGCACGCAGGCACCTACGACCAGAAGGTGCAAGGGGGCAAGTAGCCCCCG
CTCCATGCCTCGCGGCACTGCCGGTGTCCCCAGAGCAGGGACTCTGTCACCTCGCACTTCATTACATTCCTGTACTAACTGGGGCAGAAC
TCAGACGGGTGCCCCAGAGGGGGCTGGGGGGCGGCCAGGCCCAGGCCTCCCTCCTGCCCCTCCTCCTACCGGATGCCCCCAGCACTCCCC
TCTCAAACCAGGTTTGGGCCCCAGTTCGCTGACCCTCCTAATACACCTGCCTCGTCCTCAGCCATTTCCAAAGTGTCTCGCGGATCACAC
CACACTGGGCACGTGGTTTGCAGGTCAAAGGGGCGTTTTAAAGCAGCTGGCTGTCATGGCAACAGGAGGCTGTGCTGACCTCCTGAGCGG
CAGACACCTTCCAGGAGCCCTGAGGGTGGCAGGAGCTAACCCCAACCAGCAGGCAACTAACACGGAATTGGCCCCACACCGGACGTGGGA
GGTGTCTGTGGGGCCCGAGGCCTGTCCTGTGTGCAGCGGACACCACGGGGCCTTCCTGCTTTCCTGGGCAGAGGGCAGAGTGAGGCCACC
TGGCGGGGGTGCTGGGCGCCTGGCACATGTGTGGGGAAGCCGGTCACATGGACACACCTGTGCACACATGCCTACAGGCCAGCTCTGTGC
CAAGGGCAACCTAGGTAAAACGAAAGCCGTCAGGGGCAGTGGGCGGCTTCCCGGCTGACCACAGTGGCTTGGACTGTGAGGGTAGAGTAG
GCTCGCTTTGCTTTCCTGAGAAGATGCGGTGGCTGCCTATGTTCTCAGAGCGGGTCTGGGAAGATTCAGAATGTCCGGTCCCTGTGGTGT
TGCCAGGCAAGAGACACGAAGTGCCGAGACACTCCTCGCCTCACCGCGTGACAGAGCCTCTGCCCGGCCCTCCCGTTCGCCCGTCCTCAC
TAGCTGCACCCTGTTTGCTCGCAGACCTCCCATTGCCACAGCCCAAGCACCTTCTTCAACTCTCCCAAAATGGCTCAGCCTAACCTCTCC
TGGCCAATCCCCCCCGCCGGAGAGCAGGACACTAGGGAGGACCCCCAGTCCTGCAGTGTCTGTGGGGGTTTCTCTGCCAGCAGGGGGCTG
AGCAGAGCCCATCCAGGACACTCCACACTGCCAGGACACACCCAGGCGGCCCGCCCTTGCCTGTCTGCACCTGGGGAGAAGCCGGCGCTC
CTGCTCCCTCCTGGGGAGGCTGACGGGTGTGGCCACCCGCTGTCACAATGGCACACTGCCACTGTCCCTTGGCACGCACACAGCCACAGC
CACACGTGTGACCTGCTGGGCCGTGGTTCTGGAGTCTACCTGCGGATGAGCCTGCGGCAGTCCTGGGGAAACTTTTCCAGAGCCTGTTAG
CCCGTGGCTACGGTCAGGCTCTGGCCAGGGCAGAGGGCTGCCCAGGGCCAGGCTCACAGTACAGGAGGGTGGCGAGGCCCCTCCCTCACT
GGCACGCATGAGCACCACCCGCCTCCCCGACTCCCAAGAGTGCACCTGCTGCGGCCACAGCTCCGTGGAAGGACTCCCCCTACCTGAGCA
GAGCAGAAGCCCCAGGGCGGAGCTCCCAGCCAGCATGGTCCGCTGAGGGCTGGGGGGCGGTCTCCGAGGCCCCTCAACAGAGAAGCCTCC
ACCTGAGGATGGGGAGGACCTGGCAGGCAGCTTCCACGGCAGGGCTGGGAAGTTCAGTGCCTGGAAATAAAGAGCAAGGAAAAATGGACC
TCAGGCTTCGTGGCTCCTTTAGGATGTCACCTCACCGGCCTGGGGAAGGCGGGGGGTGCCCAAGCCCAGCCCTGTGCCCCCGCTGAACCT
GGCTGGACCGCGTGTGAAAGGCAGAACTAACGTGCGGAAACATTTGAAAACAACTCTGAATGTGCGGTTCGGAATCACCCGATCACAGAC
GAGCGGTCACCGGAATCGCCCGGTCACAGACGAGCAGTCATCGGACTCACCCGATCACAGACGAGCGGTCACCGGAATCGCCCGATCACA
GACGAGCGGCCACCGGAATCGCCCAATCACAGACAAGCAGTCATCGGAATCACCCGATCACAGACGAGCAGTCATCGGACTCACCCGATC
ACAGACGAGCGGTCACCAGACTCGCCCGATCACAGACGAGCAGTCATCGGAATCACCCGATCACAGACGAGCAGTCATCGGACTCACCCG
ATCACAGACGAGCGGTCACCAGAATCGCCCGATCACAGACGAGCAGTCATCGGAATCACCCGATCACAGACGAGTGGCCACCGGAATCAC
CCGATAACAGCCCATCACAACTCCAAAGCCCTTGTGTTGAAAAGGCCGAGGACGAGTGGTCACCAAACAGGGTGGCTCCCCAGGTCCCGA
AGCCTGAGACCCGGAAGGCCCTGGCACCCTTACACCCTCGGACTCCTGCCCTCCTCGGCCTCCCTGGCCCCAGCGCGGCTCCACCCTGGG
CTGCGTCTCCTGGTCACAGGCTGCGTTTCTCCTTTCTGTCCGTGGGCAGCCCAGTCCCCACAGTCACGGCCAAGCCACGCAGAACGAACA
TGACTCCAGAGGACCTCGCCCTGGAGCTGAGCCTGGCGCCGGGTCAGGACGGAGGGAAGGGCGGGTTGGGGTCCGCGGGTCCTCACACCG
CACGGCAGGCACAGAGGCTCGCCAGGCCCTGATCCGGTCTGTGGGGACGAGGGACACTGAGGAGAGGTGCTGGGCACCAGGACGCTGCCT
CCTGGTCCCTGGTTGGCCTCAGACAAGCACGGCCTCGAGAAAAGAGCCAAGCGCATCGGGAGCACACCAGAAACCGGCCCTGAGCACGAG
AAGAGCCTCCGCCCGGCCCGGGCACCACCCGACCTCGCAGGGAGCAGGCCCTGTCACCGACGGGTCACCTCGCCCACACGGCCAGCACCG
ACTCACCACAGCCCTTCCCAGACCTGGCTGGAGTGGCCGGAGCGGCGGGGCTCATGGCTCCCATCTTGGCCCCTGGAGGTGAGCTCATTC
ACAGAAGTGGTCCCTTCACTCTGAGAGAGAAAATCGTGGCGTGCATCCCAAACCCTAGGCCACGCCTGTGGGTTTCGTGAATGAGATCGA
GGCTGCTGTGGCACCCTGCCCGTCCTGGCCTGGAGCACCCTGGGATCCTGGAGGGAGAGGCCCCACGCCCCCACTCTCCCTCCACACTTC
CAGGGTTGGTGCCCACGAGTTAGAGGCACGCCCTCCCCCAGCGGCCCTCAGGCTTTTCTCAGACATGCGGGAGCCAGGAGAGCACCCTTC
TCCACTCAGCTCCAAAGCGAATCTTTGAAAACACCCACTCGGCTCCCATCTCTGTCACCTAGCCAGGAGGGGTAGCAAAAATAAAGTCAC
GAGGACATAGTGGTCACCACTGTCAGTTACAACTTGTCTGTGGAATCCGTAATTGCATCTGTGTGCCGCCTCCGAACACAGAACATTGTT
TGGACGGCAGCCCCACTGCACATAACAGACCCGTGCATCTTCCTCAGTCAGTTTCTGAATATTGTGAATTCAGGCAGGTGTGTGTTCTCT
TCTGCATGTTTTTATGCACTGCCAATTAGCTTCTACTAACCACGGTTCAACAGAAAATAAATGTGTATTTGTGAATAACAAACTGCACAA
CCTGCAAACCAGGAGAGAGGGACAGGTTCTGTCAGGGGTGACACCAGGACACAGGGACAGGTTCTGTCGGGGGTGACACCAGGACACAGG
GACAGGTTCTGTCATGGGTGACACGAGGACACAGGGACAGGTTCTATCATGGGTGACACCAGGAGAGAGGGACAGGTTCTGTTGGGGGTG
ACAAGAGGAGACAGGGACAGGTTCTGTCGGGGGTGACACCAGGAGAGAGGGACAGGTTCTGTCAGGGGTGACACCAGGAGAGAGGGACAG
GTTCTGTTGGGGGTGACACCAGGACACAGGAATAGGTTCTGTCGGGAGGACAGTGCTGATCGTGTCTCAGCATCAGGAAAGGAGAAAGGC
AGAGGGAGAGCGCTGAGAAGACTGTTCACGCCAGAGTGCTTATTTATTTTTAATTTACTGCTATAGGATAAGCAACCAGGTAGTGTTCCT
AACAATTAGCGTTACCAAAATTAAAGTTCAAATTATATGTTTAAAATATTGTAGAAGATATATATTTATACTGGACTACTTTTACACCTT
CTAATATCCTGTCCAAGTTTGGGCGCAGATGGTGGAGTTGGGCTGGCATCATGTCCTGTGGCCGCCCCACTTGCCTGTTGGTGCCACTCC
ATCCCGGGCCCCAGGGATGCCAGCTCAGGGCTGACCACAGCAGCCCTGCGTGGGCATCACCTCCTACCCCAGCCCCCATCCTGGGCTGCT
GCGGCCGC

>10230_10230_1_BRD9-TPPP_BRD9_chr5_886706_ENST00000323510_TPPP_chr5_666238_ENST00000360578_length(amino acids)=297AA_BP=0
MKGYQSLVFNFFFLKLSAENESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFK
LMCDNAMTYNRPDTVYYKLAKKILHAGFKMMSKERLLALKRSMSFMQDMDFSQQAALLGNEDTAVEEPVPEVVPVQVETAKKSKKPSREV
IRGKSCRTITFEQFQEALEELAKKRFKDKSSEEAVREVHRLIEGKAPIISGVTKAISSPTVSRLTDTTKFTGSHKERFDPSGKGKGKAGR
VDLVDESGYVSGYKHAGTYDQKVQGGK

--------------------------------------------------------------
>10230_10230_2_BRD9-TPPP_BRD9_chr5_886706_ENST00000388890_TPPP_chr5_666238_ENST00000360578_length(transcript)=5168nt_BP=485nt
ATGAAGGGATACCAAAGTCTTGTATTCAATTTTTTTTTCCTTAAATTGTCAGCCGAAAATGAGAGCACACCTATTCAGCAACTCCTGGAA
CACTTCCTCCGCCAGCTTCAGAGAAAAGATCCCCATGGATTTTTTGCTTTTCCTGTCACGGATGCAATTGCTCCTGGATATTCAATGATA
ATAAAACATCCCATGGATTTTGGCACCATGAAAGACAAAATTGTAGCTAATGAATACAAGTCAGTTACGGAATTTAAGGCAGATTTCAAG
CTGATGTGTGATAATGCAATGACATACAATAGGCCAGATACCGTGTACTACAAGTTGGCGAAGAAGATCCTTCACGCAGGCTTTAAGATG
ATGAGCAAACAGGCAGCTCTTTTGGGCAATGAAGATACAGCTGTTGAGGAACCTGTCCCTGAAGTTGTACCAGTACAAGTAGAAACTGCC
AAGAAATCCAAAAAGCCGAGTAGAGAAGTTATCAGAGGGAAGTCTTGCCGGACCATCACCTTTGAGCAGTTCCAGGAGGCGCTGGAGGAG
CTCGCCAAGAAGCGATTCAAAGACAAGAGCAGCGAGGAGGCCGTTCGCGAGGTGCACAGGCTCATCGAGGGCAAGGCGCCCATCATCTCA
GGGGTGACGAAAGCCATCTCGTCGCCCACAGTGTCGAGGCTCACGGACACCACCAAGTTCACGGGCTCCCACAAGGAGCGCTTCGACCCC
TCTGGCAAGGGCAAGGGCAAGGCTGGCCGCGTGGATCTGGTGGACGAGTCAGGCTATGTGTCCGGCTACAAGCACGCAGGCACCTACGAC
CAGAAGGTGCAAGGGGGCAAGTAGCCCCCGCTCCATGCCTCGCGGCACTGCCGGTGTCCCCAGAGCAGGGACTCTGTCACCTCGCACTTC
ATTACATTCCTGTACTAACTGGGGCAGAACTCAGACGGGTGCCCCAGAGGGGGCTGGGGGGCGGCCAGGCCCAGGCCTCCCTCCTGCCCC
TCCTCCTACCGGATGCCCCCAGCACTCCCCTCTCAAACCAGGTTTGGGCCCCAGTTCGCTGACCCTCCTAATACACCTGCCTCGTCCTCA
GCCATTTCCAAAGTGTCTCGCGGATCACACCACACTGGGCACGTGGTTTGCAGGTCAAAGGGGCGTTTTAAAGCAGCTGGCTGTCATGGC
AACAGGAGGCTGTGCTGACCTCCTGAGCGGCAGACACCTTCCAGGAGCCCTGAGGGTGGCAGGAGCTAACCCCAACCAGCAGGCAACTAA
CACGGAATTGGCCCCACACCGGACGTGGGAGGTGTCTGTGGGGCCCGAGGCCTGTCCTGTGTGCAGCGGACACCACGGGGCCTTCCTGCT
TTCCTGGGCAGAGGGCAGAGTGAGGCCACCTGGCGGGGGTGCTGGGCGCCTGGCACATGTGTGGGGAAGCCGGTCACATGGACACACCTG
TGCACACATGCCTACAGGCCAGCTCTGTGCCAAGGGCAACCTAGGTAAAACGAAAGCCGTCAGGGGCAGTGGGCGGCTTCCCGGCTGACC
ACAGTGGCTTGGACTGTGAGGGTAGAGTAGGCTCGCTTTGCTTTCCTGAGAAGATGCGGTGGCTGCCTATGTTCTCAGAGCGGGTCTGGG
AAGATTCAGAATGTCCGGTCCCTGTGGTGTTGCCAGGCAAGAGACACGAAGTGCCGAGACACTCCTCGCCTCACCGCGTGACAGAGCCTC
TGCCCGGCCCTCCCGTTCGCCCGTCCTCACTAGCTGCACCCTGTTTGCTCGCAGACCTCCCATTGCCACAGCCCAAGCACCTTCTTCAAC
TCTCCCAAAATGGCTCAGCCTAACCTCTCCTGGCCAATCCCCCCCGCCGGAGAGCAGGACACTAGGGAGGACCCCCAGTCCTGCAGTGTC
TGTGGGGGTTTCTCTGCCAGCAGGGGGCTGAGCAGAGCCCATCCAGGACACTCCACACTGCCAGGACACACCCAGGCGGCCCGCCCTTGC
CTGTCTGCACCTGGGGAGAAGCCGGCGCTCCTGCTCCCTCCTGGGGAGGCTGACGGGTGTGGCCACCCGCTGTCACAATGGCACACTGCC
ACTGTCCCTTGGCACGCACACAGCCACAGCCACACGTGTGACCTGCTGGGCCGTGGTTCTGGAGTCTACCTGCGGATGAGCCTGCGGCAG
TCCTGGGGAAACTTTTCCAGAGCCTGTTAGCCCGTGGCTACGGTCAGGCTCTGGCCAGGGCAGAGGGCTGCCCAGGGCCAGGCTCACAGT
ACAGGAGGGTGGCGAGGCCCCTCCCTCACTGGCACGCATGAGCACCACCCGCCTCCCCGACTCCCAAGAGTGCACCTGCTGCGGCCACAG
CTCCGTGGAAGGACTCCCCCTACCTGAGCAGAGCAGAAGCCCCAGGGCGGAGCTCCCAGCCAGCATGGTCCGCTGAGGGCTGGGGGGCGG
TCTCCGAGGCCCCTCAACAGAGAAGCCTCCACCTGAGGATGGGGAGGACCTGGCAGGCAGCTTCCACGGCAGGGCTGGGAAGTTCAGTGC
CTGGAAATAAAGAGCAAGGAAAAATGGACCTCAGGCTTCGTGGCTCCTTTAGGATGTCACCTCACCGGCCTGGGGAAGGCGGGGGGTGCC
CAAGCCCAGCCCTGTGCCCCCGCTGAACCTGGCTGGACCGCGTGTGAAAGGCAGAACTAACGTGCGGAAACATTTGAAAACAACTCTGAA
TGTGCGGTTCGGAATCACCCGATCACAGACGAGCGGTCACCGGAATCGCCCGGTCACAGACGAGCAGTCATCGGACTCACCCGATCACAG
ACGAGCGGTCACCGGAATCGCCCGATCACAGACGAGCGGCCACCGGAATCGCCCAATCACAGACAAGCAGTCATCGGAATCACCCGATCA
CAGACGAGCAGTCATCGGACTCACCCGATCACAGACGAGCGGTCACCAGACTCGCCCGATCACAGACGAGCAGTCATCGGAATCACCCGA
TCACAGACGAGCAGTCATCGGACTCACCCGATCACAGACGAGCGGTCACCAGAATCGCCCGATCACAGACGAGCAGTCATCGGAATCACC
CGATCACAGACGAGTGGCCACCGGAATCACCCGATAACAGCCCATCACAACTCCAAAGCCCTTGTGTTGAAAAGGCCGAGGACGAGTGGT
CACCAAACAGGGTGGCTCCCCAGGTCCCGAAGCCTGAGACCCGGAAGGCCCTGGCACCCTTACACCCTCGGACTCCTGCCCTCCTCGGCC
TCCCTGGCCCCAGCGCGGCTCCACCCTGGGCTGCGTCTCCTGGTCACAGGCTGCGTTTCTCCTTTCTGTCCGTGGGCAGCCCAGTCCCCA
CAGTCACGGCCAAGCCACGCAGAACGAACATGACTCCAGAGGACCTCGCCCTGGAGCTGAGCCTGGCGCCGGGTCAGGACGGAGGGAAGG
GCGGGTTGGGGTCCGCGGGTCCTCACACCGCACGGCAGGCACAGAGGCTCGCCAGGCCCTGATCCGGTCTGTGGGGACGAGGGACACTGA
GGAGAGGTGCTGGGCACCAGGACGCTGCCTCCTGGTCCCTGGTTGGCCTCAGACAAGCACGGCCTCGAGAAAAGAGCCAAGCGCATCGGG
AGCACACCAGAAACCGGCCCTGAGCACGAGAAGAGCCTCCGCCCGGCCCGGGCACCACCCGACCTCGCAGGGAGCAGGCCCTGTCACCGA
CGGGTCACCTCGCCCACACGGCCAGCACCGACTCACCACAGCCCTTCCCAGACCTGGCTGGAGTGGCCGGAGCGGCGGGGCTCATGGCTC
CCATCTTGGCCCCTGGAGGTGAGCTCATTCACAGAAGTGGTCCCTTCACTCTGAGAGAGAAAATCGTGGCGTGCATCCCAAACCCTAGGC
CACGCCTGTGGGTTTCGTGAATGAGATCGAGGCTGCTGTGGCACCCTGCCCGTCCTGGCCTGGAGCACCCTGGGATCCTGGAGGGAGAGG
CCCCACGCCCCCACTCTCCCTCCACACTTCCAGGGTTGGTGCCCACGAGTTAGAGGCACGCCCTCCCCCAGCGGCCCTCAGGCTTTTCTC
AGACATGCGGGAGCCAGGAGAGCACCCTTCTCCACTCAGCTCCAAAGCGAATCTTTGAAAACACCCACTCGGCTCCCATCTCTGTCACCT
AGCCAGGAGGGGTAGCAAAAATAAAGTCACGAGGACATAGTGGTCACCACTGTCAGTTACAACTTGTCTGTGGAATCCGTAATTGCATCT
GTGTGCCGCCTCCGAACACAGAACATTGTTTGGACGGCAGCCCCACTGCACATAACAGACCCGTGCATCTTCCTCAGTCAGTTTCTGAAT
ATTGTGAATTCAGGCAGGTGTGTGTTCTCTTCTGCATGTTTTTATGCACTGCCAATTAGCTTCTACTAACCACGGTTCAACAGAAAATAA
ATGTGTATTTGTGAATAACAAACTGCACAACCTGCAAACCAGGAGAGAGGGACAGGTTCTGTCAGGGGTGACACCAGGACACAGGGACAG
GTTCTGTCGGGGGTGACACCAGGACACAGGGACAGGTTCTGTCATGGGTGACACGAGGACACAGGGACAGGTTCTATCATGGGTGACACC
AGGAGAGAGGGACAGGTTCTGTTGGGGGTGACAAGAGGAGACAGGGACAGGTTCTGTCGGGGGTGACACCAGGAGAGAGGGACAGGTTCT
GTCAGGGGTGACACCAGGAGAGAGGGACAGGTTCTGTTGGGGGTGACACCAGGACACAGGAATAGGTTCTGTCGGGAGGACAGTGCTGAT
CGTGTCTCAGCATCAGGAAAGGAGAAAGGCAGAGGGAGAGCGCTGAGAAGACTGTTCACGCCAGAGTGCTTATTTATTTTTAATTTACTG
CTATAGGATAAGCAACCAGGTAGTGTTCCTAACAATTAGCGTTACCAAAATTAAAGTTCAAATTATATGTTTAAAATATTGTAGAAGATA
TATATTTATACTGGACTACTTTTACACCTTCTAATATCCTGTCCAAGTTTGGGCGCAGATGGTGGAGTTGGGCTGGCATCATGTCCTGTG
GCCGCCCCACTTGCCTGTTGGTGCCACTCCATCCCGGGCCCCAGGGATGCCAGCTCAGGGCTGACCACAGCAGCCCTGCGTGGGCATCAC
CTCCTACCCCAGCCCCCATCCTGGGCTGCTGCGGCCGC

>10230_10230_2_BRD9-TPPP_BRD9_chr5_886706_ENST00000388890_TPPP_chr5_666238_ENST00000360578_length(amino acids)=277AA_BP=0
MKGYQSLVFNFFFLKLSAENESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFK
LMCDNAMTYNRPDTVYYKLAKKILHAGFKMMSKQAALLGNEDTAVEEPVPEVVPVQVETAKKSKKPSREVIRGKSCRTITFEQFQEALEE
LAKKRFKDKSSEEAVREVHRLIEGKAPIISGVTKAISSPTVSRLTDTTKFTGSHKERFDPSGKGKGKAGRVDLVDESGYVSGYKHAGTYD
QKVQGGK

--------------------------------------------------------------
>10230_10230_3_BRD9-TPPP_BRD9_chr5_886706_ENST00000467963_TPPP_chr5_666238_ENST00000360578_length(transcript)=5683nt_BP=1000nt
CTGCCGCGGCCCCGCCTCGCCCCGTTTCCGGCGCGGCCCAGCGAGCTCGGCAACCTCGGCGCAGCGAGCGCGGGCGGCCAGCCAGGGCCA
GGGGGCGGTGGCGGCCAAGGTCCGACCGGGTGCCAGCTGTTCCCAGCCCCCGCCTCGGGCCCGCCGCCGGCGCCGCCATGGGCAAGAAGC
ACAAGAAGCACAAGGCCGAGTGGCGCTCGTCCTACGAGGATTATGCCGACAAGCCCCTGGAGAAGCCTCTAAAGCTAGTCCTGAAGGTCG
GAGGAAGTGAAGTGACTGAACTCTCAGGATCCGGCCACGACTCCAGTTACTATGATGACAGGTCAGACCATGAGCGAGAGAGGCACAAAG
AAAAGAAAAAGAAGAAGAAGAAGAAGTCCGAGAAGGAGAAGCATCTGGACGATGAGGAAAGAAGGAAGCGAAAGGAAGAGAAGAAGCGGA
AGCGAGAGAGGGAGCACTGTGACACGGAGGGAGAGGCTGACGACTTTGATCCTGGGAAGAAGGTGGAGGTGGAGCCGCCCCCAGATCGGC
CAGTCCGAGCGTGCCGGACACAGCCAGCCGAAAATGAGAGCACACCTATTCAGCAACTCCTGGAACACTTCCTCCGCCAGCTTCAGAGAA
AAGATCCCCATGGATTTTTTGCTTTTCCTGTCACGGATGCAATTGCTCCTGGATATTCAATGATAATAAAACATCCCATGGATTTTGGCA
CCATGAAAGACAAAATTGTAGCTAATGAATACAAGTCAGTTACGGAATTTAAGGCAGATTTCAAGCTGATGTGTGATAATGCAATGACAT
ACAATAGGCCAGATACCGTGTACTACAAGTTGGCGAAGAAGATCCTTCACGCAGGCTTTAAGATGATGAGCAAACAGGCAGCTCTTTTGG
GCAATGAAGATACAGCTGTTGAGGAACCTGTCCCTGAAGTTGTACCAGTACAAGTAGAAACTGCCAAGAAATCCAAAAAGCCGAGTAGAG
AAGTTATCAGAGGGAAGTCTTGCCGGACCATCACCTTTGAGCAGTTCCAGGAGGCGCTGGAGGAGCTCGCCAAGAAGCGATTCAAAGACA
AGAGCAGCGAGGAGGCCGTTCGCGAGGTGCACAGGCTCATCGAGGGCAAGGCGCCCATCATCTCAGGGGTGACGAAAGCCATCTCGTCGC
CCACAGTGTCGAGGCTCACGGACACCACCAAGTTCACGGGCTCCCACAAGGAGCGCTTCGACCCCTCTGGCAAGGGCAAGGGCAAGGCTG
GCCGCGTGGATCTGGTGGACGAGTCAGGCTATGTGTCCGGCTACAAGCACGCAGGCACCTACGACCAGAAGGTGCAAGGGGGCAAGTAGC
CCCCGCTCCATGCCTCGCGGCACTGCCGGTGTCCCCAGAGCAGGGACTCTGTCACCTCGCACTTCATTACATTCCTGTACTAACTGGGGC
AGAACTCAGACGGGTGCCCCAGAGGGGGCTGGGGGGCGGCCAGGCCCAGGCCTCCCTCCTGCCCCTCCTCCTACCGGATGCCCCCAGCAC
TCCCCTCTCAAACCAGGTTTGGGCCCCAGTTCGCTGACCCTCCTAATACACCTGCCTCGTCCTCAGCCATTTCCAAAGTGTCTCGCGGAT
CACACCACACTGGGCACGTGGTTTGCAGGTCAAAGGGGCGTTTTAAAGCAGCTGGCTGTCATGGCAACAGGAGGCTGTGCTGACCTCCTG
AGCGGCAGACACCTTCCAGGAGCCCTGAGGGTGGCAGGAGCTAACCCCAACCAGCAGGCAACTAACACGGAATTGGCCCCACACCGGACG
TGGGAGGTGTCTGTGGGGCCCGAGGCCTGTCCTGTGTGCAGCGGACACCACGGGGCCTTCCTGCTTTCCTGGGCAGAGGGCAGAGTGAGG
CCACCTGGCGGGGGTGCTGGGCGCCTGGCACATGTGTGGGGAAGCCGGTCACATGGACACACCTGTGCACACATGCCTACAGGCCAGCTC
TGTGCCAAGGGCAACCTAGGTAAAACGAAAGCCGTCAGGGGCAGTGGGCGGCTTCCCGGCTGACCACAGTGGCTTGGACTGTGAGGGTAG
AGTAGGCTCGCTTTGCTTTCCTGAGAAGATGCGGTGGCTGCCTATGTTCTCAGAGCGGGTCTGGGAAGATTCAGAATGTCCGGTCCCTGT
GGTGTTGCCAGGCAAGAGACACGAAGTGCCGAGACACTCCTCGCCTCACCGCGTGACAGAGCCTCTGCCCGGCCCTCCCGTTCGCCCGTC
CTCACTAGCTGCACCCTGTTTGCTCGCAGACCTCCCATTGCCACAGCCCAAGCACCTTCTTCAACTCTCCCAAAATGGCTCAGCCTAACC
TCTCCTGGCCAATCCCCCCCGCCGGAGAGCAGGACACTAGGGAGGACCCCCAGTCCTGCAGTGTCTGTGGGGGTTTCTCTGCCAGCAGGG
GGCTGAGCAGAGCCCATCCAGGACACTCCACACTGCCAGGACACACCCAGGCGGCCCGCCCTTGCCTGTCTGCACCTGGGGAGAAGCCGG
CGCTCCTGCTCCCTCCTGGGGAGGCTGACGGGTGTGGCCACCCGCTGTCACAATGGCACACTGCCACTGTCCCTTGGCACGCACACAGCC
ACAGCCACACGTGTGACCTGCTGGGCCGTGGTTCTGGAGTCTACCTGCGGATGAGCCTGCGGCAGTCCTGGGGAAACTTTTCCAGAGCCT
GTTAGCCCGTGGCTACGGTCAGGCTCTGGCCAGGGCAGAGGGCTGCCCAGGGCCAGGCTCACAGTACAGGAGGGTGGCGAGGCCCCTCCC
TCACTGGCACGCATGAGCACCACCCGCCTCCCCGACTCCCAAGAGTGCACCTGCTGCGGCCACAGCTCCGTGGAAGGACTCCCCCTACCT
GAGCAGAGCAGAAGCCCCAGGGCGGAGCTCCCAGCCAGCATGGTCCGCTGAGGGCTGGGGGGCGGTCTCCGAGGCCCCTCAACAGAGAAG
CCTCCACCTGAGGATGGGGAGGACCTGGCAGGCAGCTTCCACGGCAGGGCTGGGAAGTTCAGTGCCTGGAAATAAAGAGCAAGGAAAAAT
GGACCTCAGGCTTCGTGGCTCCTTTAGGATGTCACCTCACCGGCCTGGGGAAGGCGGGGGGTGCCCAAGCCCAGCCCTGTGCCCCCGCTG
AACCTGGCTGGACCGCGTGTGAAAGGCAGAACTAACGTGCGGAAACATTTGAAAACAACTCTGAATGTGCGGTTCGGAATCACCCGATCA
CAGACGAGCGGTCACCGGAATCGCCCGGTCACAGACGAGCAGTCATCGGACTCACCCGATCACAGACGAGCGGTCACCGGAATCGCCCGA
TCACAGACGAGCGGCCACCGGAATCGCCCAATCACAGACAAGCAGTCATCGGAATCACCCGATCACAGACGAGCAGTCATCGGACTCACC
CGATCACAGACGAGCGGTCACCAGACTCGCCCGATCACAGACGAGCAGTCATCGGAATCACCCGATCACAGACGAGCAGTCATCGGACTC
ACCCGATCACAGACGAGCGGTCACCAGAATCGCCCGATCACAGACGAGCAGTCATCGGAATCACCCGATCACAGACGAGTGGCCACCGGA
ATCACCCGATAACAGCCCATCACAACTCCAAAGCCCTTGTGTTGAAAAGGCCGAGGACGAGTGGTCACCAAACAGGGTGGCTCCCCAGGT
CCCGAAGCCTGAGACCCGGAAGGCCCTGGCACCCTTACACCCTCGGACTCCTGCCCTCCTCGGCCTCCCTGGCCCCAGCGCGGCTCCACC
CTGGGCTGCGTCTCCTGGTCACAGGCTGCGTTTCTCCTTTCTGTCCGTGGGCAGCCCAGTCCCCACAGTCACGGCCAAGCCACGCAGAAC
GAACATGACTCCAGAGGACCTCGCCCTGGAGCTGAGCCTGGCGCCGGGTCAGGACGGAGGGAAGGGCGGGTTGGGGTCCGCGGGTCCTCA
CACCGCACGGCAGGCACAGAGGCTCGCCAGGCCCTGATCCGGTCTGTGGGGACGAGGGACACTGAGGAGAGGTGCTGGGCACCAGGACGC
TGCCTCCTGGTCCCTGGTTGGCCTCAGACAAGCACGGCCTCGAGAAAAGAGCCAAGCGCATCGGGAGCACACCAGAAACCGGCCCTGAGC
ACGAGAAGAGCCTCCGCCCGGCCCGGGCACCACCCGACCTCGCAGGGAGCAGGCCCTGTCACCGACGGGTCACCTCGCCCACACGGCCAG
CACCGACTCACCACAGCCCTTCCCAGACCTGGCTGGAGTGGCCGGAGCGGCGGGGCTCATGGCTCCCATCTTGGCCCCTGGAGGTGAGCT
CATTCACAGAAGTGGTCCCTTCACTCTGAGAGAGAAAATCGTGGCGTGCATCCCAAACCCTAGGCCACGCCTGTGGGTTTCGTGAATGAG
ATCGAGGCTGCTGTGGCACCCTGCCCGTCCTGGCCTGGAGCACCCTGGGATCCTGGAGGGAGAGGCCCCACGCCCCCACTCTCCCTCCAC
ACTTCCAGGGTTGGTGCCCACGAGTTAGAGGCACGCCCTCCCCCAGCGGCCCTCAGGCTTTTCTCAGACATGCGGGAGCCAGGAGAGCAC
CCTTCTCCACTCAGCTCCAAAGCGAATCTTTGAAAACACCCACTCGGCTCCCATCTCTGTCACCTAGCCAGGAGGGGTAGCAAAAATAAA
GTCACGAGGACATAGTGGTCACCACTGTCAGTTACAACTTGTCTGTGGAATCCGTAATTGCATCTGTGTGCCGCCTCCGAACACAGAACA
TTGTTTGGACGGCAGCCCCACTGCACATAACAGACCCGTGCATCTTCCTCAGTCAGTTTCTGAATATTGTGAATTCAGGCAGGTGTGTGT
TCTCTTCTGCATGTTTTTATGCACTGCCAATTAGCTTCTACTAACCACGGTTCAACAGAAAATAAATGTGTATTTGTGAATAACAAACTG
CACAACCTGCAAACCAGGAGAGAGGGACAGGTTCTGTCAGGGGTGACACCAGGACACAGGGACAGGTTCTGTCGGGGGTGACACCAGGAC
ACAGGGACAGGTTCTGTCATGGGTGACACGAGGACACAGGGACAGGTTCTATCATGGGTGACACCAGGAGAGAGGGACAGGTTCTGTTGG
GGGTGACAAGAGGAGACAGGGACAGGTTCTGTCGGGGGTGACACCAGGAGAGAGGGACAGGTTCTGTCAGGGGTGACACCAGGAGAGAGG
GACAGGTTCTGTTGGGGGTGACACCAGGACACAGGAATAGGTTCTGTCGGGAGGACAGTGCTGATCGTGTCTCAGCATCAGGAAAGGAGA
AAGGCAGAGGGAGAGCGCTGAGAAGACTGTTCACGCCAGAGTGCTTATTTATTTTTAATTTACTGCTATAGGATAAGCAACCAGGTAGTG
TTCCTAACAATTAGCGTTACCAAAATTAAAGTTCAAATTATATGTTTAAAATATTGTAGAAGATATATATTTATACTGGACTACTTTTAC
ACCTTCTAATATCCTGTCCAAGTTTGGGCGCAGATGGTGGAGTTGGGCTGGCATCATGTCCTGTGGCCGCCCCACTTGCCTGTTGGTGCC
ACTCCATCCCGGGCCCCAGGGATGCCAGCTCAGGGCTGACCACAGCAGCCCTGCGTGGGCATCACCTCCTACCCCAGCCCCCATCCTGGG
CTGCTGCGGCCGC

>10230_10230_3_BRD9-TPPP_BRD9_chr5_886706_ENST00000467963_TPPP_chr5_666238_ENST00000360578_length(amino acids)=393AA_BP=0
MGKKHKKHKAEWRSSYEDYADKPLEKPLKLVLKVGGSEVTELSGSGHDSSYYDDRSDHERERHKEKKKKKKKKSEKEKHLDDEERRKRKE
EKKRKREREHCDTEGEADDFDPGKKVEVEPPPDRPVRACRTQPAENESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHP
MDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKMMSKQAALLGNEDTAVEEPVPEVVPVQVETAKKSK
KPSREVIRGKSCRTITFEQFQEALEELAKKRFKDKSSEEAVREVHRLIEGKAPIISGVTKAISSPTVSRLTDTTKFTGSHKERFDPSGKG
KGKAGRVDLVDESGYVSGYKHAGTYDQKVQGGK

--------------------------------------------------------------
>10230_10230_4_BRD9-TPPP_BRD9_chr5_886706_ENST00000483173_TPPP_chr5_666238_ENST00000360578_length(transcript)=5497nt_BP=814nt
TCCGGGCACGCGGACGGGGGTCCTGGGCACCGGGCGAGATTATGCCGACAAGCCCCTGGAGAAGCCTCTAAAGCTAGTCCTGAAGGTCGG
AGGAAGTGAAGTGACTGAACTCTCAGGATCCGGCCACGACTCCAGTTACTATGATGACAGGTCAGACCATGAGCGAGAGAGGCACAAAGA
AAAGAAAAAGAAGAAGAAGAAGAAGTCCGAGAAGGAGAAGCATCTGGACGATGAGGAAAGAAGGAAGCGAAAGGAAGAGAAGAAGCGGAA
GCGAGAGAGGGAGCACTGTGACACGGAGGGAGAGGCTGACGACTTTGATCCTGGGAAGAAGGTGGAGGTGGAGCCGCCCCCAGATCGGCC
AGTCCGAGCGTGCCGGACACAGCCAGCCGAAAATGAGAGCACACCTATTCAGCAACTCCTGGAACACTTCCTCCGCCAGCTTCAGAGATC
CCCATGGATTTTTTGCTTTTCCTGTCACGGATGCAATTGCTCCTGGATATTCAATGATAATAAAACATCCCATGGATTTTGGCACCATGA
AAGACAAAATTGTAGCTAATGAATACAAGTCAGTTACGGAATTTAAGGCAGATTTCAAGCTGATGTGTGATAATGCAATGACATACAATA
GGCCAGATACCGTGTACTACAAGTTGGCGAAGAAGATCCTTCACGCAGGCTTTAAGATGATGAGCAAACAGGCAGCTCTTTTGGGCAATG
AAGATACAGCTGTTGAGGAACCTGTCCCTGAAGTTGTACCAGTACAAGTAGAAACTGCCAAGAAATCCAAAAAGCCGAGTAGAGAAGTTA
TCAGAGGGAAGTCTTGCCGGACCATCACCTTTGAGCAGTTCCAGGAGGCGCTGGAGGAGCTCGCCAAGAAGCGATTCAAAGACAAGAGCA
GCGAGGAGGCCGTTCGCGAGGTGCACAGGCTCATCGAGGGCAAGGCGCCCATCATCTCAGGGGTGACGAAAGCCATCTCGTCGCCCACAG
TGTCGAGGCTCACGGACACCACCAAGTTCACGGGCTCCCACAAGGAGCGCTTCGACCCCTCTGGCAAGGGCAAGGGCAAGGCTGGCCGCG
TGGATCTGGTGGACGAGTCAGGCTATGTGTCCGGCTACAAGCACGCAGGCACCTACGACCAGAAGGTGCAAGGGGGCAAGTAGCCCCCGC
TCCATGCCTCGCGGCACTGCCGGTGTCCCCAGAGCAGGGACTCTGTCACCTCGCACTTCATTACATTCCTGTACTAACTGGGGCAGAACT
CAGACGGGTGCCCCAGAGGGGGCTGGGGGGCGGCCAGGCCCAGGCCTCCCTCCTGCCCCTCCTCCTACCGGATGCCCCCAGCACTCCCCT
CTCAAACCAGGTTTGGGCCCCAGTTCGCTGACCCTCCTAATACACCTGCCTCGTCCTCAGCCATTTCCAAAGTGTCTCGCGGATCACACC
ACACTGGGCACGTGGTTTGCAGGTCAAAGGGGCGTTTTAAAGCAGCTGGCTGTCATGGCAACAGGAGGCTGTGCTGACCTCCTGAGCGGC
AGACACCTTCCAGGAGCCCTGAGGGTGGCAGGAGCTAACCCCAACCAGCAGGCAACTAACACGGAATTGGCCCCACACCGGACGTGGGAG
GTGTCTGTGGGGCCCGAGGCCTGTCCTGTGTGCAGCGGACACCACGGGGCCTTCCTGCTTTCCTGGGCAGAGGGCAGAGTGAGGCCACCT
GGCGGGGGTGCTGGGCGCCTGGCACATGTGTGGGGAAGCCGGTCACATGGACACACCTGTGCACACATGCCTACAGGCCAGCTCTGTGCC
AAGGGCAACCTAGGTAAAACGAAAGCCGTCAGGGGCAGTGGGCGGCTTCCCGGCTGACCACAGTGGCTTGGACTGTGAGGGTAGAGTAGG
CTCGCTTTGCTTTCCTGAGAAGATGCGGTGGCTGCCTATGTTCTCAGAGCGGGTCTGGGAAGATTCAGAATGTCCGGTCCCTGTGGTGTT
GCCAGGCAAGAGACACGAAGTGCCGAGACACTCCTCGCCTCACCGCGTGACAGAGCCTCTGCCCGGCCCTCCCGTTCGCCCGTCCTCACT
AGCTGCACCCTGTTTGCTCGCAGACCTCCCATTGCCACAGCCCAAGCACCTTCTTCAACTCTCCCAAAATGGCTCAGCCTAACCTCTCCT
GGCCAATCCCCCCCGCCGGAGAGCAGGACACTAGGGAGGACCCCCAGTCCTGCAGTGTCTGTGGGGGTTTCTCTGCCAGCAGGGGGCTGA
GCAGAGCCCATCCAGGACACTCCACACTGCCAGGACACACCCAGGCGGCCCGCCCTTGCCTGTCTGCACCTGGGGAGAAGCCGGCGCTCC
TGCTCCCTCCTGGGGAGGCTGACGGGTGTGGCCACCCGCTGTCACAATGGCACACTGCCACTGTCCCTTGGCACGCACACAGCCACAGCC
ACACGTGTGACCTGCTGGGCCGTGGTTCTGGAGTCTACCTGCGGATGAGCCTGCGGCAGTCCTGGGGAAACTTTTCCAGAGCCTGTTAGC
CCGTGGCTACGGTCAGGCTCTGGCCAGGGCAGAGGGCTGCCCAGGGCCAGGCTCACAGTACAGGAGGGTGGCGAGGCCCCTCCCTCACTG
GCACGCATGAGCACCACCCGCCTCCCCGACTCCCAAGAGTGCACCTGCTGCGGCCACAGCTCCGTGGAAGGACTCCCCCTACCTGAGCAG
AGCAGAAGCCCCAGGGCGGAGCTCCCAGCCAGCATGGTCCGCTGAGGGCTGGGGGGCGGTCTCCGAGGCCCCTCAACAGAGAAGCCTCCA
CCTGAGGATGGGGAGGACCTGGCAGGCAGCTTCCACGGCAGGGCTGGGAAGTTCAGTGCCTGGAAATAAAGAGCAAGGAAAAATGGACCT
CAGGCTTCGTGGCTCCTTTAGGATGTCACCTCACCGGCCTGGGGAAGGCGGGGGGTGCCCAAGCCCAGCCCTGTGCCCCCGCTGAACCTG
GCTGGACCGCGTGTGAAAGGCAGAACTAACGTGCGGAAACATTTGAAAACAACTCTGAATGTGCGGTTCGGAATCACCCGATCACAGACG
AGCGGTCACCGGAATCGCCCGGTCACAGACGAGCAGTCATCGGACTCACCCGATCACAGACGAGCGGTCACCGGAATCGCCCGATCACAG
ACGAGCGGCCACCGGAATCGCCCAATCACAGACAAGCAGTCATCGGAATCACCCGATCACAGACGAGCAGTCATCGGACTCACCCGATCA
CAGACGAGCGGTCACCAGACTCGCCCGATCACAGACGAGCAGTCATCGGAATCACCCGATCACAGACGAGCAGTCATCGGACTCACCCGA
TCACAGACGAGCGGTCACCAGAATCGCCCGATCACAGACGAGCAGTCATCGGAATCACCCGATCACAGACGAGTGGCCACCGGAATCACC
CGATAACAGCCCATCACAACTCCAAAGCCCTTGTGTTGAAAAGGCCGAGGACGAGTGGTCACCAAACAGGGTGGCTCCCCAGGTCCCGAA
GCCTGAGACCCGGAAGGCCCTGGCACCCTTACACCCTCGGACTCCTGCCCTCCTCGGCCTCCCTGGCCCCAGCGCGGCTCCACCCTGGGC
TGCGTCTCCTGGTCACAGGCTGCGTTTCTCCTTTCTGTCCGTGGGCAGCCCAGTCCCCACAGTCACGGCCAAGCCACGCAGAACGAACAT
GACTCCAGAGGACCTCGCCCTGGAGCTGAGCCTGGCGCCGGGTCAGGACGGAGGGAAGGGCGGGTTGGGGTCCGCGGGTCCTCACACCGC
ACGGCAGGCACAGAGGCTCGCCAGGCCCTGATCCGGTCTGTGGGGACGAGGGACACTGAGGAGAGGTGCTGGGCACCAGGACGCTGCCTC
CTGGTCCCTGGTTGGCCTCAGACAAGCACGGCCTCGAGAAAAGAGCCAAGCGCATCGGGAGCACACCAGAAACCGGCCCTGAGCACGAGA
AGAGCCTCCGCCCGGCCCGGGCACCACCCGACCTCGCAGGGAGCAGGCCCTGTCACCGACGGGTCACCTCGCCCACACGGCCAGCACCGA
CTCACCACAGCCCTTCCCAGACCTGGCTGGAGTGGCCGGAGCGGCGGGGCTCATGGCTCCCATCTTGGCCCCTGGAGGTGAGCTCATTCA
CAGAAGTGGTCCCTTCACTCTGAGAGAGAAAATCGTGGCGTGCATCCCAAACCCTAGGCCACGCCTGTGGGTTTCGTGAATGAGATCGAG
GCTGCTGTGGCACCCTGCCCGTCCTGGCCTGGAGCACCCTGGGATCCTGGAGGGAGAGGCCCCACGCCCCCACTCTCCCTCCACACTTCC
AGGGTTGGTGCCCACGAGTTAGAGGCACGCCCTCCCCCAGCGGCCCTCAGGCTTTTCTCAGACATGCGGGAGCCAGGAGAGCACCCTTCT
CCACTCAGCTCCAAAGCGAATCTTTGAAAACACCCACTCGGCTCCCATCTCTGTCACCTAGCCAGGAGGGGTAGCAAAAATAAAGTCACG
AGGACATAGTGGTCACCACTGTCAGTTACAACTTGTCTGTGGAATCCGTAATTGCATCTGTGTGCCGCCTCCGAACACAGAACATTGTTT
GGACGGCAGCCCCACTGCACATAACAGACCCGTGCATCTTCCTCAGTCAGTTTCTGAATATTGTGAATTCAGGCAGGTGTGTGTTCTCTT
CTGCATGTTTTTATGCACTGCCAATTAGCTTCTACTAACCACGGTTCAACAGAAAATAAATGTGTATTTGTGAATAACAAACTGCACAAC
CTGCAAACCAGGAGAGAGGGACAGGTTCTGTCAGGGGTGACACCAGGACACAGGGACAGGTTCTGTCGGGGGTGACACCAGGACACAGGG
ACAGGTTCTGTCATGGGTGACACGAGGACACAGGGACAGGTTCTATCATGGGTGACACCAGGAGAGAGGGACAGGTTCTGTTGGGGGTGA
CAAGAGGAGACAGGGACAGGTTCTGTCGGGGGTGACACCAGGAGAGAGGGACAGGTTCTGTCAGGGGTGACACCAGGAGAGAGGGACAGG
TTCTGTTGGGGGTGACACCAGGACACAGGAATAGGTTCTGTCGGGAGGACAGTGCTGATCGTGTCTCAGCATCAGGAAAGGAGAAAGGCA
GAGGGAGAGCGCTGAGAAGACTGTTCACGCCAGAGTGCTTATTTATTTTTAATTTACTGCTATAGGATAAGCAACCAGGTAGTGTTCCTA
ACAATTAGCGTTACCAAAATTAAAGTTCAAATTATATGTTTAAAATATTGTAGAAGATATATATTTATACTGGACTACTTTTACACCTTC
TAATATCCTGTCCAAGTTTGGGCGCAGATGGTGGAGTTGGGCTGGCATCATGTCCTGTGGCCGCCCCACTTGCCTGTTGGTGCCACTCCA
TCCCGGGCCCCAGGGATGCCAGCTCAGGGCTGACCACAGCAGCCCTGCGTGGGCATCACCTCCTACCCCAGCCCCCATCCTGGGCTGCTG
CGGCCGC

>10230_10230_4_BRD9-TPPP_BRD9_chr5_886706_ENST00000483173_TPPP_chr5_666238_ENST00000360578_length(amino acids)=352AA_BP=1
MNSQDPATTPVTMMTGQTMSERGTKKRKRRRRRSPRRRSIWTMRKEGSERKRRSGSERGSTVTRRERLTTLILGRRWRWSRPQIGQSERA
GHSQPKMRAHLFSNSWNTSSASFRDPHGFFAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTV
YYKLAKKILHAGFKMMSKQAALLGNEDTAVEEPVPEVVPVQVETAKKSKKPSREVIRGKSCRTITFEQFQEALEELAKKRFKDKSSEEAV
REVHRLIEGKAPIISGVTKAISSPTVSRLTDTTKFTGSHKERFDPSGKGKGKAGRVDLVDESGYVSGYKHAGTYDQKVQGGK

--------------------------------------------------------------
>10230_10230_5_BRD9-TPPP_BRD9_chr5_886707_ENST00000323510_TPPP_chr5_666238_ENST00000360578_length(transcript)=5228nt_BP=545nt
ATGAAGGGATACCAAAGTCTTGTATTCAATTTTTTTTTCCTTAAATTGTCAGCCGAAAATGAGAGCACACCTATTCAGCAACTCCTGGAA
CACTTCCTCCGCCAGCTTCAGAGAAAAGATCCCCATGGATTTTTTGCTTTTCCTGTCACGGATGCAATTGCTCCTGGATATTCAATGATA
ATAAAACATCCCATGGATTTTGGCACCATGAAAGACAAAATTGTAGCTAATGAATACAAGTCAGTTACGGAATTTAAGGCAGATTTCAAG
CTGATGTGTGATAATGCAATGACATACAATAGGCCAGATACCGTGTACTACAAGTTGGCGAAGAAGATCCTTCACGCAGGCTTTAAGATG
ATGAGCAAAGAGCGGCTGTTAGCTTTGAAGCGCAGCATGTCGTTTATGCAGGACATGGATTTTTCTCAGCAGGCAGCTCTTTTGGGCAAT
GAAGATACAGCTGTTGAGGAACCTGTCCCTGAAGTTGTACCAGTACAAGTAGAAACTGCCAAGAAATCCAAAAAGCCGAGTAGAGAAGTT
ATCAGAGGGAAGTCTTGCCGGACCATCACCTTTGAGCAGTTCCAGGAGGCGCTGGAGGAGCTCGCCAAGAAGCGATTCAAAGACAAGAGC
AGCGAGGAGGCCGTTCGCGAGGTGCACAGGCTCATCGAGGGCAAGGCGCCCATCATCTCAGGGGTGACGAAAGCCATCTCGTCGCCCACA
GTGTCGAGGCTCACGGACACCACCAAGTTCACGGGCTCCCACAAGGAGCGCTTCGACCCCTCTGGCAAGGGCAAGGGCAAGGCTGGCCGC
GTGGATCTGGTGGACGAGTCAGGCTATGTGTCCGGCTACAAGCACGCAGGCACCTACGACCAGAAGGTGCAAGGGGGCAAGTAGCCCCCG
CTCCATGCCTCGCGGCACTGCCGGTGTCCCCAGAGCAGGGACTCTGTCACCTCGCACTTCATTACATTCCTGTACTAACTGGGGCAGAAC
TCAGACGGGTGCCCCAGAGGGGGCTGGGGGGCGGCCAGGCCCAGGCCTCCCTCCTGCCCCTCCTCCTACCGGATGCCCCCAGCACTCCCC
TCTCAAACCAGGTTTGGGCCCCAGTTCGCTGACCCTCCTAATACACCTGCCTCGTCCTCAGCCATTTCCAAAGTGTCTCGCGGATCACAC
CACACTGGGCACGTGGTTTGCAGGTCAAAGGGGCGTTTTAAAGCAGCTGGCTGTCATGGCAACAGGAGGCTGTGCTGACCTCCTGAGCGG
CAGACACCTTCCAGGAGCCCTGAGGGTGGCAGGAGCTAACCCCAACCAGCAGGCAACTAACACGGAATTGGCCCCACACCGGACGTGGGA
GGTGTCTGTGGGGCCCGAGGCCTGTCCTGTGTGCAGCGGACACCACGGGGCCTTCCTGCTTTCCTGGGCAGAGGGCAGAGTGAGGCCACC
TGGCGGGGGTGCTGGGCGCCTGGCACATGTGTGGGGAAGCCGGTCACATGGACACACCTGTGCACACATGCCTACAGGCCAGCTCTGTGC
CAAGGGCAACCTAGGTAAAACGAAAGCCGTCAGGGGCAGTGGGCGGCTTCCCGGCTGACCACAGTGGCTTGGACTGTGAGGGTAGAGTAG
GCTCGCTTTGCTTTCCTGAGAAGATGCGGTGGCTGCCTATGTTCTCAGAGCGGGTCTGGGAAGATTCAGAATGTCCGGTCCCTGTGGTGT
TGCCAGGCAAGAGACACGAAGTGCCGAGACACTCCTCGCCTCACCGCGTGACAGAGCCTCTGCCCGGCCCTCCCGTTCGCCCGTCCTCAC
TAGCTGCACCCTGTTTGCTCGCAGACCTCCCATTGCCACAGCCCAAGCACCTTCTTCAACTCTCCCAAAATGGCTCAGCCTAACCTCTCC
TGGCCAATCCCCCCCGCCGGAGAGCAGGACACTAGGGAGGACCCCCAGTCCTGCAGTGTCTGTGGGGGTTTCTCTGCCAGCAGGGGGCTG
AGCAGAGCCCATCCAGGACACTCCACACTGCCAGGACACACCCAGGCGGCCCGCCCTTGCCTGTCTGCACCTGGGGAGAAGCCGGCGCTC
CTGCTCCCTCCTGGGGAGGCTGACGGGTGTGGCCACCCGCTGTCACAATGGCACACTGCCACTGTCCCTTGGCACGCACACAGCCACAGC
CACACGTGTGACCTGCTGGGCCGTGGTTCTGGAGTCTACCTGCGGATGAGCCTGCGGCAGTCCTGGGGAAACTTTTCCAGAGCCTGTTAG
CCCGTGGCTACGGTCAGGCTCTGGCCAGGGCAGAGGGCTGCCCAGGGCCAGGCTCACAGTACAGGAGGGTGGCGAGGCCCCTCCCTCACT
GGCACGCATGAGCACCACCCGCCTCCCCGACTCCCAAGAGTGCACCTGCTGCGGCCACAGCTCCGTGGAAGGACTCCCCCTACCTGAGCA
GAGCAGAAGCCCCAGGGCGGAGCTCCCAGCCAGCATGGTCCGCTGAGGGCTGGGGGGCGGTCTCCGAGGCCCCTCAACAGAGAAGCCTCC
ACCTGAGGATGGGGAGGACCTGGCAGGCAGCTTCCACGGCAGGGCTGGGAAGTTCAGTGCCTGGAAATAAAGAGCAAGGAAAAATGGACC
TCAGGCTTCGTGGCTCCTTTAGGATGTCACCTCACCGGCCTGGGGAAGGCGGGGGGTGCCCAAGCCCAGCCCTGTGCCCCCGCTGAACCT
GGCTGGACCGCGTGTGAAAGGCAGAACTAACGTGCGGAAACATTTGAAAACAACTCTGAATGTGCGGTTCGGAATCACCCGATCACAGAC
GAGCGGTCACCGGAATCGCCCGGTCACAGACGAGCAGTCATCGGACTCACCCGATCACAGACGAGCGGTCACCGGAATCGCCCGATCACA
GACGAGCGGCCACCGGAATCGCCCAATCACAGACAAGCAGTCATCGGAATCACCCGATCACAGACGAGCAGTCATCGGACTCACCCGATC
ACAGACGAGCGGTCACCAGACTCGCCCGATCACAGACGAGCAGTCATCGGAATCACCCGATCACAGACGAGCAGTCATCGGACTCACCCG
ATCACAGACGAGCGGTCACCAGAATCGCCCGATCACAGACGAGCAGTCATCGGAATCACCCGATCACAGACGAGTGGCCACCGGAATCAC
CCGATAACAGCCCATCACAACTCCAAAGCCCTTGTGTTGAAAAGGCCGAGGACGAGTGGTCACCAAACAGGGTGGCTCCCCAGGTCCCGA
AGCCTGAGACCCGGAAGGCCCTGGCACCCTTACACCCTCGGACTCCTGCCCTCCTCGGCCTCCCTGGCCCCAGCGCGGCTCCACCCTGGG
CTGCGTCTCCTGGTCACAGGCTGCGTTTCTCCTTTCTGTCCGTGGGCAGCCCAGTCCCCACAGTCACGGCCAAGCCACGCAGAACGAACA
TGACTCCAGAGGACCTCGCCCTGGAGCTGAGCCTGGCGCCGGGTCAGGACGGAGGGAAGGGCGGGTTGGGGTCCGCGGGTCCTCACACCG
CACGGCAGGCACAGAGGCTCGCCAGGCCCTGATCCGGTCTGTGGGGACGAGGGACACTGAGGAGAGGTGCTGGGCACCAGGACGCTGCCT
CCTGGTCCCTGGTTGGCCTCAGACAAGCACGGCCTCGAGAAAAGAGCCAAGCGCATCGGGAGCACACCAGAAACCGGCCCTGAGCACGAG
AAGAGCCTCCGCCCGGCCCGGGCACCACCCGACCTCGCAGGGAGCAGGCCCTGTCACCGACGGGTCACCTCGCCCACACGGCCAGCACCG
ACTCACCACAGCCCTTCCCAGACCTGGCTGGAGTGGCCGGAGCGGCGGGGCTCATGGCTCCCATCTTGGCCCCTGGAGGTGAGCTCATTC
ACAGAAGTGGTCCCTTCACTCTGAGAGAGAAAATCGTGGCGTGCATCCCAAACCCTAGGCCACGCCTGTGGGTTTCGTGAATGAGATCGA
GGCTGCTGTGGCACCCTGCCCGTCCTGGCCTGGAGCACCCTGGGATCCTGGAGGGAGAGGCCCCACGCCCCCACTCTCCCTCCACACTTC
CAGGGTTGGTGCCCACGAGTTAGAGGCACGCCCTCCCCCAGCGGCCCTCAGGCTTTTCTCAGACATGCGGGAGCCAGGAGAGCACCCTTC
TCCACTCAGCTCCAAAGCGAATCTTTGAAAACACCCACTCGGCTCCCATCTCTGTCACCTAGCCAGGAGGGGTAGCAAAAATAAAGTCAC
GAGGACATAGTGGTCACCACTGTCAGTTACAACTTGTCTGTGGAATCCGTAATTGCATCTGTGTGCCGCCTCCGAACACAGAACATTGTT
TGGACGGCAGCCCCACTGCACATAACAGACCCGTGCATCTTCCTCAGTCAGTTTCTGAATATTGTGAATTCAGGCAGGTGTGTGTTCTCT
TCTGCATGTTTTTATGCACTGCCAATTAGCTTCTACTAACCACGGTTCAACAGAAAATAAATGTGTATTTGTGAATAACAAACTGCACAA
CCTGCAAACCAGGAGAGAGGGACAGGTTCTGTCAGGGGTGACACCAGGACACAGGGACAGGTTCTGTCGGGGGTGACACCAGGACACAGG
GACAGGTTCTGTCATGGGTGACACGAGGACACAGGGACAGGTTCTATCATGGGTGACACCAGGAGAGAGGGACAGGTTCTGTTGGGGGTG
ACAAGAGGAGACAGGGACAGGTTCTGTCGGGGGTGACACCAGGAGAGAGGGACAGGTTCTGTCAGGGGTGACACCAGGAGAGAGGGACAG
GTTCTGTTGGGGGTGACACCAGGACACAGGAATAGGTTCTGTCGGGAGGACAGTGCTGATCGTGTCTCAGCATCAGGAAAGGAGAAAGGC
AGAGGGAGAGCGCTGAGAAGACTGTTCACGCCAGAGTGCTTATTTATTTTTAATTTACTGCTATAGGATAAGCAACCAGGTAGTGTTCCT
AACAATTAGCGTTACCAAAATTAAAGTTCAAATTATATGTTTAAAATATTGTAGAAGATATATATTTATACTGGACTACTTTTACACCTT
CTAATATCCTGTCCAAGTTTGGGCGCAGATGGTGGAGTTGGGCTGGCATCATGTCCTGTGGCCGCCCCACTTGCCTGTTGGTGCCACTCC
ATCCCGGGCCCCAGGGATGCCAGCTCAGGGCTGACCACAGCAGCCCTGCGTGGGCATCACCTCCTACCCCAGCCCCCATCCTGGGCTGCT
GCGGCCGC

>10230_10230_5_BRD9-TPPP_BRD9_chr5_886707_ENST00000323510_TPPP_chr5_666238_ENST00000360578_length(amino acids)=297AA_BP=0
MKGYQSLVFNFFFLKLSAENESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFK
LMCDNAMTYNRPDTVYYKLAKKILHAGFKMMSKERLLALKRSMSFMQDMDFSQQAALLGNEDTAVEEPVPEVVPVQVETAKKSKKPSREV
IRGKSCRTITFEQFQEALEELAKKRFKDKSSEEAVREVHRLIEGKAPIISGVTKAISSPTVSRLTDTTKFTGSHKERFDPSGKGKGKAGR
VDLVDESGYVSGYKHAGTYDQKVQGGK

--------------------------------------------------------------
>10230_10230_6_BRD9-TPPP_BRD9_chr5_886707_ENST00000388890_TPPP_chr5_666238_ENST00000360578_length(transcript)=5168nt_BP=485nt
ATGAAGGGATACCAAAGTCTTGTATTCAATTTTTTTTTCCTTAAATTGTCAGCCGAAAATGAGAGCACACCTATTCAGCAACTCCTGGAA
CACTTCCTCCGCCAGCTTCAGAGAAAAGATCCCCATGGATTTTTTGCTTTTCCTGTCACGGATGCAATTGCTCCTGGATATTCAATGATA
ATAAAACATCCCATGGATTTTGGCACCATGAAAGACAAAATTGTAGCTAATGAATACAAGTCAGTTACGGAATTTAAGGCAGATTTCAAG
CTGATGTGTGATAATGCAATGACATACAATAGGCCAGATACCGTGTACTACAAGTTGGCGAAGAAGATCCTTCACGCAGGCTTTAAGATG
ATGAGCAAACAGGCAGCTCTTTTGGGCAATGAAGATACAGCTGTTGAGGAACCTGTCCCTGAAGTTGTACCAGTACAAGTAGAAACTGCC
AAGAAATCCAAAAAGCCGAGTAGAGAAGTTATCAGAGGGAAGTCTTGCCGGACCATCACCTTTGAGCAGTTCCAGGAGGCGCTGGAGGAG
CTCGCCAAGAAGCGATTCAAAGACAAGAGCAGCGAGGAGGCCGTTCGCGAGGTGCACAGGCTCATCGAGGGCAAGGCGCCCATCATCTCA
GGGGTGACGAAAGCCATCTCGTCGCCCACAGTGTCGAGGCTCACGGACACCACCAAGTTCACGGGCTCCCACAAGGAGCGCTTCGACCCC
TCTGGCAAGGGCAAGGGCAAGGCTGGCCGCGTGGATCTGGTGGACGAGTCAGGCTATGTGTCCGGCTACAAGCACGCAGGCACCTACGAC
CAGAAGGTGCAAGGGGGCAAGTAGCCCCCGCTCCATGCCTCGCGGCACTGCCGGTGTCCCCAGAGCAGGGACTCTGTCACCTCGCACTTC
ATTACATTCCTGTACTAACTGGGGCAGAACTCAGACGGGTGCCCCAGAGGGGGCTGGGGGGCGGCCAGGCCCAGGCCTCCCTCCTGCCCC
TCCTCCTACCGGATGCCCCCAGCACTCCCCTCTCAAACCAGGTTTGGGCCCCAGTTCGCTGACCCTCCTAATACACCTGCCTCGTCCTCA
GCCATTTCCAAAGTGTCTCGCGGATCACACCACACTGGGCACGTGGTTTGCAGGTCAAAGGGGCGTTTTAAAGCAGCTGGCTGTCATGGC
AACAGGAGGCTGTGCTGACCTCCTGAGCGGCAGACACCTTCCAGGAGCCCTGAGGGTGGCAGGAGCTAACCCCAACCAGCAGGCAACTAA
CACGGAATTGGCCCCACACCGGACGTGGGAGGTGTCTGTGGGGCCCGAGGCCTGTCCTGTGTGCAGCGGACACCACGGGGCCTTCCTGCT
TTCCTGGGCAGAGGGCAGAGTGAGGCCACCTGGCGGGGGTGCTGGGCGCCTGGCACATGTGTGGGGAAGCCGGTCACATGGACACACCTG
TGCACACATGCCTACAGGCCAGCTCTGTGCCAAGGGCAACCTAGGTAAAACGAAAGCCGTCAGGGGCAGTGGGCGGCTTCCCGGCTGACC
ACAGTGGCTTGGACTGTGAGGGTAGAGTAGGCTCGCTTTGCTTTCCTGAGAAGATGCGGTGGCTGCCTATGTTCTCAGAGCGGGTCTGGG
AAGATTCAGAATGTCCGGTCCCTGTGGTGTTGCCAGGCAAGAGACACGAAGTGCCGAGACACTCCTCGCCTCACCGCGTGACAGAGCCTC
TGCCCGGCCCTCCCGTTCGCCCGTCCTCACTAGCTGCACCCTGTTTGCTCGCAGACCTCCCATTGCCACAGCCCAAGCACCTTCTTCAAC
TCTCCCAAAATGGCTCAGCCTAACCTCTCCTGGCCAATCCCCCCCGCCGGAGAGCAGGACACTAGGGAGGACCCCCAGTCCTGCAGTGTC
TGTGGGGGTTTCTCTGCCAGCAGGGGGCTGAGCAGAGCCCATCCAGGACACTCCACACTGCCAGGACACACCCAGGCGGCCCGCCCTTGC
CTGTCTGCACCTGGGGAGAAGCCGGCGCTCCTGCTCCCTCCTGGGGAGGCTGACGGGTGTGGCCACCCGCTGTCACAATGGCACACTGCC
ACTGTCCCTTGGCACGCACACAGCCACAGCCACACGTGTGACCTGCTGGGCCGTGGTTCTGGAGTCTACCTGCGGATGAGCCTGCGGCAG
TCCTGGGGAAACTTTTCCAGAGCCTGTTAGCCCGTGGCTACGGTCAGGCTCTGGCCAGGGCAGAGGGCTGCCCAGGGCCAGGCTCACAGT
ACAGGAGGGTGGCGAGGCCCCTCCCTCACTGGCACGCATGAGCACCACCCGCCTCCCCGACTCCCAAGAGTGCACCTGCTGCGGCCACAG
CTCCGTGGAAGGACTCCCCCTACCTGAGCAGAGCAGAAGCCCCAGGGCGGAGCTCCCAGCCAGCATGGTCCGCTGAGGGCTGGGGGGCGG
TCTCCGAGGCCCCTCAACAGAGAAGCCTCCACCTGAGGATGGGGAGGACCTGGCAGGCAGCTTCCACGGCAGGGCTGGGAAGTTCAGTGC
CTGGAAATAAAGAGCAAGGAAAAATGGACCTCAGGCTTCGTGGCTCCTTTAGGATGTCACCTCACCGGCCTGGGGAAGGCGGGGGGTGCC
CAAGCCCAGCCCTGTGCCCCCGCTGAACCTGGCTGGACCGCGTGTGAAAGGCAGAACTAACGTGCGGAAACATTTGAAAACAACTCTGAA
TGTGCGGTTCGGAATCACCCGATCACAGACGAGCGGTCACCGGAATCGCCCGGTCACAGACGAGCAGTCATCGGACTCACCCGATCACAG
ACGAGCGGTCACCGGAATCGCCCGATCACAGACGAGCGGCCACCGGAATCGCCCAATCACAGACAAGCAGTCATCGGAATCACCCGATCA
CAGACGAGCAGTCATCGGACTCACCCGATCACAGACGAGCGGTCACCAGACTCGCCCGATCACAGACGAGCAGTCATCGGAATCACCCGA
TCACAGACGAGCAGTCATCGGACTCACCCGATCACAGACGAGCGGTCACCAGAATCGCCCGATCACAGACGAGCAGTCATCGGAATCACC
CGATCACAGACGAGTGGCCACCGGAATCACCCGATAACAGCCCATCACAACTCCAAAGCCCTTGTGTTGAAAAGGCCGAGGACGAGTGGT
CACCAAACAGGGTGGCTCCCCAGGTCCCGAAGCCTGAGACCCGGAAGGCCCTGGCACCCTTACACCCTCGGACTCCTGCCCTCCTCGGCC
TCCCTGGCCCCAGCGCGGCTCCACCCTGGGCTGCGTCTCCTGGTCACAGGCTGCGTTTCTCCTTTCTGTCCGTGGGCAGCCCAGTCCCCA
CAGTCACGGCCAAGCCACGCAGAACGAACATGACTCCAGAGGACCTCGCCCTGGAGCTGAGCCTGGCGCCGGGTCAGGACGGAGGGAAGG
GCGGGTTGGGGTCCGCGGGTCCTCACACCGCACGGCAGGCACAGAGGCTCGCCAGGCCCTGATCCGGTCTGTGGGGACGAGGGACACTGA
GGAGAGGTGCTGGGCACCAGGACGCTGCCTCCTGGTCCCTGGTTGGCCTCAGACAAGCACGGCCTCGAGAAAAGAGCCAAGCGCATCGGG
AGCACACCAGAAACCGGCCCTGAGCACGAGAAGAGCCTCCGCCCGGCCCGGGCACCACCCGACCTCGCAGGGAGCAGGCCCTGTCACCGA
CGGGTCACCTCGCCCACACGGCCAGCACCGACTCACCACAGCCCTTCCCAGACCTGGCTGGAGTGGCCGGAGCGGCGGGGCTCATGGCTC
CCATCTTGGCCCCTGGAGGTGAGCTCATTCACAGAAGTGGTCCCTTCACTCTGAGAGAGAAAATCGTGGCGTGCATCCCAAACCCTAGGC
CACGCCTGTGGGTTTCGTGAATGAGATCGAGGCTGCTGTGGCACCCTGCCCGTCCTGGCCTGGAGCACCCTGGGATCCTGGAGGGAGAGG
CCCCACGCCCCCACTCTCCCTCCACACTTCCAGGGTTGGTGCCCACGAGTTAGAGGCACGCCCTCCCCCAGCGGCCCTCAGGCTTTTCTC
AGACATGCGGGAGCCAGGAGAGCACCCTTCTCCACTCAGCTCCAAAGCGAATCTTTGAAAACACCCACTCGGCTCCCATCTCTGTCACCT
AGCCAGGAGGGGTAGCAAAAATAAAGTCACGAGGACATAGTGGTCACCACTGTCAGTTACAACTTGTCTGTGGAATCCGTAATTGCATCT
GTGTGCCGCCTCCGAACACAGAACATTGTTTGGACGGCAGCCCCACTGCACATAACAGACCCGTGCATCTTCCTCAGTCAGTTTCTGAAT
ATTGTGAATTCAGGCAGGTGTGTGTTCTCTTCTGCATGTTTTTATGCACTGCCAATTAGCTTCTACTAACCACGGTTCAACAGAAAATAA
ATGTGTATTTGTGAATAACAAACTGCACAACCTGCAAACCAGGAGAGAGGGACAGGTTCTGTCAGGGGTGACACCAGGACACAGGGACAG
GTTCTGTCGGGGGTGACACCAGGACACAGGGACAGGTTCTGTCATGGGTGACACGAGGACACAGGGACAGGTTCTATCATGGGTGACACC
AGGAGAGAGGGACAGGTTCTGTTGGGGGTGACAAGAGGAGACAGGGACAGGTTCTGTCGGGGGTGACACCAGGAGAGAGGGACAGGTTCT
GTCAGGGGTGACACCAGGAGAGAGGGACAGGTTCTGTTGGGGGTGACACCAGGACACAGGAATAGGTTCTGTCGGGAGGACAGTGCTGAT
CGTGTCTCAGCATCAGGAAAGGAGAAAGGCAGAGGGAGAGCGCTGAGAAGACTGTTCACGCCAGAGTGCTTATTTATTTTTAATTTACTG
CTATAGGATAAGCAACCAGGTAGTGTTCCTAACAATTAGCGTTACCAAAATTAAAGTTCAAATTATATGTTTAAAATATTGTAGAAGATA
TATATTTATACTGGACTACTTTTACACCTTCTAATATCCTGTCCAAGTTTGGGCGCAGATGGTGGAGTTGGGCTGGCATCATGTCCTGTG
GCCGCCCCACTTGCCTGTTGGTGCCACTCCATCCCGGGCCCCAGGGATGCCAGCTCAGGGCTGACCACAGCAGCCCTGCGTGGGCATCAC
CTCCTACCCCAGCCCCCATCCTGGGCTGCTGCGGCCGC

>10230_10230_6_BRD9-TPPP_BRD9_chr5_886707_ENST00000388890_TPPP_chr5_666238_ENST00000360578_length(amino acids)=277AA_BP=0
MKGYQSLVFNFFFLKLSAENESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFK
LMCDNAMTYNRPDTVYYKLAKKILHAGFKMMSKQAALLGNEDTAVEEPVPEVVPVQVETAKKSKKPSREVIRGKSCRTITFEQFQEALEE
LAKKRFKDKSSEEAVREVHRLIEGKAPIISGVTKAISSPTVSRLTDTTKFTGSHKERFDPSGKGKGKAGRVDLVDESGYVSGYKHAGTYD
QKVQGGK

--------------------------------------------------------------
>10230_10230_7_BRD9-TPPP_BRD9_chr5_886707_ENST00000467963_TPPP_chr5_666238_ENST00000360578_length(transcript)=5683nt_BP=1000nt
CTGCCGCGGCCCCGCCTCGCCCCGTTTCCGGCGCGGCCCAGCGAGCTCGGCAACCTCGGCGCAGCGAGCGCGGGCGGCCAGCCAGGGCCA
GGGGGCGGTGGCGGCCAAGGTCCGACCGGGTGCCAGCTGTTCCCAGCCCCCGCCTCGGGCCCGCCGCCGGCGCCGCCATGGGCAAGAAGC
ACAAGAAGCACAAGGCCGAGTGGCGCTCGTCCTACGAGGATTATGCCGACAAGCCCCTGGAGAAGCCTCTAAAGCTAGTCCTGAAGGTCG
GAGGAAGTGAAGTGACTGAACTCTCAGGATCCGGCCACGACTCCAGTTACTATGATGACAGGTCAGACCATGAGCGAGAGAGGCACAAAG
AAAAGAAAAAGAAGAAGAAGAAGAAGTCCGAGAAGGAGAAGCATCTGGACGATGAGGAAAGAAGGAAGCGAAAGGAAGAGAAGAAGCGGA
AGCGAGAGAGGGAGCACTGTGACACGGAGGGAGAGGCTGACGACTTTGATCCTGGGAAGAAGGTGGAGGTGGAGCCGCCCCCAGATCGGC
CAGTCCGAGCGTGCCGGACACAGCCAGCCGAAAATGAGAGCACACCTATTCAGCAACTCCTGGAACACTTCCTCCGCCAGCTTCAGAGAA
AAGATCCCCATGGATTTTTTGCTTTTCCTGTCACGGATGCAATTGCTCCTGGATATTCAATGATAATAAAACATCCCATGGATTTTGGCA
CCATGAAAGACAAAATTGTAGCTAATGAATACAAGTCAGTTACGGAATTTAAGGCAGATTTCAAGCTGATGTGTGATAATGCAATGACAT
ACAATAGGCCAGATACCGTGTACTACAAGTTGGCGAAGAAGATCCTTCACGCAGGCTTTAAGATGATGAGCAAACAGGCAGCTCTTTTGG
GCAATGAAGATACAGCTGTTGAGGAACCTGTCCCTGAAGTTGTACCAGTACAAGTAGAAACTGCCAAGAAATCCAAAAAGCCGAGTAGAG
AAGTTATCAGAGGGAAGTCTTGCCGGACCATCACCTTTGAGCAGTTCCAGGAGGCGCTGGAGGAGCTCGCCAAGAAGCGATTCAAAGACA
AGAGCAGCGAGGAGGCCGTTCGCGAGGTGCACAGGCTCATCGAGGGCAAGGCGCCCATCATCTCAGGGGTGACGAAAGCCATCTCGTCGC
CCACAGTGTCGAGGCTCACGGACACCACCAAGTTCACGGGCTCCCACAAGGAGCGCTTCGACCCCTCTGGCAAGGGCAAGGGCAAGGCTG
GCCGCGTGGATCTGGTGGACGAGTCAGGCTATGTGTCCGGCTACAAGCACGCAGGCACCTACGACCAGAAGGTGCAAGGGGGCAAGTAGC
CCCCGCTCCATGCCTCGCGGCACTGCCGGTGTCCCCAGAGCAGGGACTCTGTCACCTCGCACTTCATTACATTCCTGTACTAACTGGGGC
AGAACTCAGACGGGTGCCCCAGAGGGGGCTGGGGGGCGGCCAGGCCCAGGCCTCCCTCCTGCCCCTCCTCCTACCGGATGCCCCCAGCAC
TCCCCTCTCAAACCAGGTTTGGGCCCCAGTTCGCTGACCCTCCTAATACACCTGCCTCGTCCTCAGCCATTTCCAAAGTGTCTCGCGGAT
CACACCACACTGGGCACGTGGTTTGCAGGTCAAAGGGGCGTTTTAAAGCAGCTGGCTGTCATGGCAACAGGAGGCTGTGCTGACCTCCTG
AGCGGCAGACACCTTCCAGGAGCCCTGAGGGTGGCAGGAGCTAACCCCAACCAGCAGGCAACTAACACGGAATTGGCCCCACACCGGACG
TGGGAGGTGTCTGTGGGGCCCGAGGCCTGTCCTGTGTGCAGCGGACACCACGGGGCCTTCCTGCTTTCCTGGGCAGAGGGCAGAGTGAGG
CCACCTGGCGGGGGTGCTGGGCGCCTGGCACATGTGTGGGGAAGCCGGTCACATGGACACACCTGTGCACACATGCCTACAGGCCAGCTC
TGTGCCAAGGGCAACCTAGGTAAAACGAAAGCCGTCAGGGGCAGTGGGCGGCTTCCCGGCTGACCACAGTGGCTTGGACTGTGAGGGTAG
AGTAGGCTCGCTTTGCTTTCCTGAGAAGATGCGGTGGCTGCCTATGTTCTCAGAGCGGGTCTGGGAAGATTCAGAATGTCCGGTCCCTGT
GGTGTTGCCAGGCAAGAGACACGAAGTGCCGAGACACTCCTCGCCTCACCGCGTGACAGAGCCTCTGCCCGGCCCTCCCGTTCGCCCGTC
CTCACTAGCTGCACCCTGTTTGCTCGCAGACCTCCCATTGCCACAGCCCAAGCACCTTCTTCAACTCTCCCAAAATGGCTCAGCCTAACC
TCTCCTGGCCAATCCCCCCCGCCGGAGAGCAGGACACTAGGGAGGACCCCCAGTCCTGCAGTGTCTGTGGGGGTTTCTCTGCCAGCAGGG
GGCTGAGCAGAGCCCATCCAGGACACTCCACACTGCCAGGACACACCCAGGCGGCCCGCCCTTGCCTGTCTGCACCTGGGGAGAAGCCGG
CGCTCCTGCTCCCTCCTGGGGAGGCTGACGGGTGTGGCCACCCGCTGTCACAATGGCACACTGCCACTGTCCCTTGGCACGCACACAGCC
ACAGCCACACGTGTGACCTGCTGGGCCGTGGTTCTGGAGTCTACCTGCGGATGAGCCTGCGGCAGTCCTGGGGAAACTTTTCCAGAGCCT
GTTAGCCCGTGGCTACGGTCAGGCTCTGGCCAGGGCAGAGGGCTGCCCAGGGCCAGGCTCACAGTACAGGAGGGTGGCGAGGCCCCTCCC
TCACTGGCACGCATGAGCACCACCCGCCTCCCCGACTCCCAAGAGTGCACCTGCTGCGGCCACAGCTCCGTGGAAGGACTCCCCCTACCT
GAGCAGAGCAGAAGCCCCAGGGCGGAGCTCCCAGCCAGCATGGTCCGCTGAGGGCTGGGGGGCGGTCTCCGAGGCCCCTCAACAGAGAAG
CCTCCACCTGAGGATGGGGAGGACCTGGCAGGCAGCTTCCACGGCAGGGCTGGGAAGTTCAGTGCCTGGAAATAAAGAGCAAGGAAAAAT
GGACCTCAGGCTTCGTGGCTCCTTTAGGATGTCACCTCACCGGCCTGGGGAAGGCGGGGGGTGCCCAAGCCCAGCCCTGTGCCCCCGCTG
AACCTGGCTGGACCGCGTGTGAAAGGCAGAACTAACGTGCGGAAACATTTGAAAACAACTCTGAATGTGCGGTTCGGAATCACCCGATCA
CAGACGAGCGGTCACCGGAATCGCCCGGTCACAGACGAGCAGTCATCGGACTCACCCGATCACAGACGAGCGGTCACCGGAATCGCCCGA
TCACAGACGAGCGGCCACCGGAATCGCCCAATCACAGACAAGCAGTCATCGGAATCACCCGATCACAGACGAGCAGTCATCGGACTCACC
CGATCACAGACGAGCGGTCACCAGACTCGCCCGATCACAGACGAGCAGTCATCGGAATCACCCGATCACAGACGAGCAGTCATCGGACTC
ACCCGATCACAGACGAGCGGTCACCAGAATCGCCCGATCACAGACGAGCAGTCATCGGAATCACCCGATCACAGACGAGTGGCCACCGGA
ATCACCCGATAACAGCCCATCACAACTCCAAAGCCCTTGTGTTGAAAAGGCCGAGGACGAGTGGTCACCAAACAGGGTGGCTCCCCAGGT
CCCGAAGCCTGAGACCCGGAAGGCCCTGGCACCCTTACACCCTCGGACTCCTGCCCTCCTCGGCCTCCCTGGCCCCAGCGCGGCTCCACC
CTGGGCTGCGTCTCCTGGTCACAGGCTGCGTTTCTCCTTTCTGTCCGTGGGCAGCCCAGTCCCCACAGTCACGGCCAAGCCACGCAGAAC
GAACATGACTCCAGAGGACCTCGCCCTGGAGCTGAGCCTGGCGCCGGGTCAGGACGGAGGGAAGGGCGGGTTGGGGTCCGCGGGTCCTCA
CACCGCACGGCAGGCACAGAGGCTCGCCAGGCCCTGATCCGGTCTGTGGGGACGAGGGACACTGAGGAGAGGTGCTGGGCACCAGGACGC
TGCCTCCTGGTCCCTGGTTGGCCTCAGACAAGCACGGCCTCGAGAAAAGAGCCAAGCGCATCGGGAGCACACCAGAAACCGGCCCTGAGC
ACGAGAAGAGCCTCCGCCCGGCCCGGGCACCACCCGACCTCGCAGGGAGCAGGCCCTGTCACCGACGGGTCACCTCGCCCACACGGCCAG
CACCGACTCACCACAGCCCTTCCCAGACCTGGCTGGAGTGGCCGGAGCGGCGGGGCTCATGGCTCCCATCTTGGCCCCTGGAGGTGAGCT
CATTCACAGAAGTGGTCCCTTCACTCTGAGAGAGAAAATCGTGGCGTGCATCCCAAACCCTAGGCCACGCCTGTGGGTTTCGTGAATGAG
ATCGAGGCTGCTGTGGCACCCTGCCCGTCCTGGCCTGGAGCACCCTGGGATCCTGGAGGGAGAGGCCCCACGCCCCCACTCTCCCTCCAC
ACTTCCAGGGTTGGTGCCCACGAGTTAGAGGCACGCCCTCCCCCAGCGGCCCTCAGGCTTTTCTCAGACATGCGGGAGCCAGGAGAGCAC
CCTTCTCCACTCAGCTCCAAAGCGAATCTTTGAAAACACCCACTCGGCTCCCATCTCTGTCACCTAGCCAGGAGGGGTAGCAAAAATAAA
GTCACGAGGACATAGTGGTCACCACTGTCAGTTACAACTTGTCTGTGGAATCCGTAATTGCATCTGTGTGCCGCCTCCGAACACAGAACA
TTGTTTGGACGGCAGCCCCACTGCACATAACAGACCCGTGCATCTTCCTCAGTCAGTTTCTGAATATTGTGAATTCAGGCAGGTGTGTGT
TCTCTTCTGCATGTTTTTATGCACTGCCAATTAGCTTCTACTAACCACGGTTCAACAGAAAATAAATGTGTATTTGTGAATAACAAACTG
CACAACCTGCAAACCAGGAGAGAGGGACAGGTTCTGTCAGGGGTGACACCAGGACACAGGGACAGGTTCTGTCGGGGGTGACACCAGGAC
ACAGGGACAGGTTCTGTCATGGGTGACACGAGGACACAGGGACAGGTTCTATCATGGGTGACACCAGGAGAGAGGGACAGGTTCTGTTGG
GGGTGACAAGAGGAGACAGGGACAGGTTCTGTCGGGGGTGACACCAGGAGAGAGGGACAGGTTCTGTCAGGGGTGACACCAGGAGAGAGG
GACAGGTTCTGTTGGGGGTGACACCAGGACACAGGAATAGGTTCTGTCGGGAGGACAGTGCTGATCGTGTCTCAGCATCAGGAAAGGAGA
AAGGCAGAGGGAGAGCGCTGAGAAGACTGTTCACGCCAGAGTGCTTATTTATTTTTAATTTACTGCTATAGGATAAGCAACCAGGTAGTG
TTCCTAACAATTAGCGTTACCAAAATTAAAGTTCAAATTATATGTTTAAAATATTGTAGAAGATATATATTTATACTGGACTACTTTTAC
ACCTTCTAATATCCTGTCCAAGTTTGGGCGCAGATGGTGGAGTTGGGCTGGCATCATGTCCTGTGGCCGCCCCACTTGCCTGTTGGTGCC
ACTCCATCCCGGGCCCCAGGGATGCCAGCTCAGGGCTGACCACAGCAGCCCTGCGTGGGCATCACCTCCTACCCCAGCCCCCATCCTGGG
CTGCTGCGGCCGC

>10230_10230_7_BRD9-TPPP_BRD9_chr5_886707_ENST00000467963_TPPP_chr5_666238_ENST00000360578_length(amino acids)=393AA_BP=0
MGKKHKKHKAEWRSSYEDYADKPLEKPLKLVLKVGGSEVTELSGSGHDSSYYDDRSDHERERHKEKKKKKKKKSEKEKHLDDEERRKRKE
EKKRKREREHCDTEGEADDFDPGKKVEVEPPPDRPVRACRTQPAENESTPIQQLLEHFLRQLQRKDPHGFFAFPVTDAIAPGYSMIIKHP
MDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTVYYKLAKKILHAGFKMMSKQAALLGNEDTAVEEPVPEVVPVQVETAKKSK
KPSREVIRGKSCRTITFEQFQEALEELAKKRFKDKSSEEAVREVHRLIEGKAPIISGVTKAISSPTVSRLTDTTKFTGSHKERFDPSGKG
KGKAGRVDLVDESGYVSGYKHAGTYDQKVQGGK

--------------------------------------------------------------
>10230_10230_8_BRD9-TPPP_BRD9_chr5_886707_ENST00000483173_TPPP_chr5_666238_ENST00000360578_length(transcript)=5497nt_BP=814nt
TCCGGGCACGCGGACGGGGGTCCTGGGCACCGGGCGAGATTATGCCGACAAGCCCCTGGAGAAGCCTCTAAAGCTAGTCCTGAAGGTCGG
AGGAAGTGAAGTGACTGAACTCTCAGGATCCGGCCACGACTCCAGTTACTATGATGACAGGTCAGACCATGAGCGAGAGAGGCACAAAGA
AAAGAAAAAGAAGAAGAAGAAGAAGTCCGAGAAGGAGAAGCATCTGGACGATGAGGAAAGAAGGAAGCGAAAGGAAGAGAAGAAGCGGAA
GCGAGAGAGGGAGCACTGTGACACGGAGGGAGAGGCTGACGACTTTGATCCTGGGAAGAAGGTGGAGGTGGAGCCGCCCCCAGATCGGCC
AGTCCGAGCGTGCCGGACACAGCCAGCCGAAAATGAGAGCACACCTATTCAGCAACTCCTGGAACACTTCCTCCGCCAGCTTCAGAGATC
CCCATGGATTTTTTGCTTTTCCTGTCACGGATGCAATTGCTCCTGGATATTCAATGATAATAAAACATCCCATGGATTTTGGCACCATGA
AAGACAAAATTGTAGCTAATGAATACAAGTCAGTTACGGAATTTAAGGCAGATTTCAAGCTGATGTGTGATAATGCAATGACATACAATA
GGCCAGATACCGTGTACTACAAGTTGGCGAAGAAGATCCTTCACGCAGGCTTTAAGATGATGAGCAAACAGGCAGCTCTTTTGGGCAATG
AAGATACAGCTGTTGAGGAACCTGTCCCTGAAGTTGTACCAGTACAAGTAGAAACTGCCAAGAAATCCAAAAAGCCGAGTAGAGAAGTTA
TCAGAGGGAAGTCTTGCCGGACCATCACCTTTGAGCAGTTCCAGGAGGCGCTGGAGGAGCTCGCCAAGAAGCGATTCAAAGACAAGAGCA
GCGAGGAGGCCGTTCGCGAGGTGCACAGGCTCATCGAGGGCAAGGCGCCCATCATCTCAGGGGTGACGAAAGCCATCTCGTCGCCCACAG
TGTCGAGGCTCACGGACACCACCAAGTTCACGGGCTCCCACAAGGAGCGCTTCGACCCCTCTGGCAAGGGCAAGGGCAAGGCTGGCCGCG
TGGATCTGGTGGACGAGTCAGGCTATGTGTCCGGCTACAAGCACGCAGGCACCTACGACCAGAAGGTGCAAGGGGGCAAGTAGCCCCCGC
TCCATGCCTCGCGGCACTGCCGGTGTCCCCAGAGCAGGGACTCTGTCACCTCGCACTTCATTACATTCCTGTACTAACTGGGGCAGAACT
CAGACGGGTGCCCCAGAGGGGGCTGGGGGGCGGCCAGGCCCAGGCCTCCCTCCTGCCCCTCCTCCTACCGGATGCCCCCAGCACTCCCCT
CTCAAACCAGGTTTGGGCCCCAGTTCGCTGACCCTCCTAATACACCTGCCTCGTCCTCAGCCATTTCCAAAGTGTCTCGCGGATCACACC
ACACTGGGCACGTGGTTTGCAGGTCAAAGGGGCGTTTTAAAGCAGCTGGCTGTCATGGCAACAGGAGGCTGTGCTGACCTCCTGAGCGGC
AGACACCTTCCAGGAGCCCTGAGGGTGGCAGGAGCTAACCCCAACCAGCAGGCAACTAACACGGAATTGGCCCCACACCGGACGTGGGAG
GTGTCTGTGGGGCCCGAGGCCTGTCCTGTGTGCAGCGGACACCACGGGGCCTTCCTGCTTTCCTGGGCAGAGGGCAGAGTGAGGCCACCT
GGCGGGGGTGCTGGGCGCCTGGCACATGTGTGGGGAAGCCGGTCACATGGACACACCTGTGCACACATGCCTACAGGCCAGCTCTGTGCC
AAGGGCAACCTAGGTAAAACGAAAGCCGTCAGGGGCAGTGGGCGGCTTCCCGGCTGACCACAGTGGCTTGGACTGTGAGGGTAGAGTAGG
CTCGCTTTGCTTTCCTGAGAAGATGCGGTGGCTGCCTATGTTCTCAGAGCGGGTCTGGGAAGATTCAGAATGTCCGGTCCCTGTGGTGTT
GCCAGGCAAGAGACACGAAGTGCCGAGACACTCCTCGCCTCACCGCGTGACAGAGCCTCTGCCCGGCCCTCCCGTTCGCCCGTCCTCACT
AGCTGCACCCTGTTTGCTCGCAGACCTCCCATTGCCACAGCCCAAGCACCTTCTTCAACTCTCCCAAAATGGCTCAGCCTAACCTCTCCT
GGCCAATCCCCCCCGCCGGAGAGCAGGACACTAGGGAGGACCCCCAGTCCTGCAGTGTCTGTGGGGGTTTCTCTGCCAGCAGGGGGCTGA
GCAGAGCCCATCCAGGACACTCCACACTGCCAGGACACACCCAGGCGGCCCGCCCTTGCCTGTCTGCACCTGGGGAGAAGCCGGCGCTCC
TGCTCCCTCCTGGGGAGGCTGACGGGTGTGGCCACCCGCTGTCACAATGGCACACTGCCACTGTCCCTTGGCACGCACACAGCCACAGCC
ACACGTGTGACCTGCTGGGCCGTGGTTCTGGAGTCTACCTGCGGATGAGCCTGCGGCAGTCCTGGGGAAACTTTTCCAGAGCCTGTTAGC
CCGTGGCTACGGTCAGGCTCTGGCCAGGGCAGAGGGCTGCCCAGGGCCAGGCTCACAGTACAGGAGGGTGGCGAGGCCCCTCCCTCACTG
GCACGCATGAGCACCACCCGCCTCCCCGACTCCCAAGAGTGCACCTGCTGCGGCCACAGCTCCGTGGAAGGACTCCCCCTACCTGAGCAG
AGCAGAAGCCCCAGGGCGGAGCTCCCAGCCAGCATGGTCCGCTGAGGGCTGGGGGGCGGTCTCCGAGGCCCCTCAACAGAGAAGCCTCCA
CCTGAGGATGGGGAGGACCTGGCAGGCAGCTTCCACGGCAGGGCTGGGAAGTTCAGTGCCTGGAAATAAAGAGCAAGGAAAAATGGACCT
CAGGCTTCGTGGCTCCTTTAGGATGTCACCTCACCGGCCTGGGGAAGGCGGGGGGTGCCCAAGCCCAGCCCTGTGCCCCCGCTGAACCTG
GCTGGACCGCGTGTGAAAGGCAGAACTAACGTGCGGAAACATTTGAAAACAACTCTGAATGTGCGGTTCGGAATCACCCGATCACAGACG
AGCGGTCACCGGAATCGCCCGGTCACAGACGAGCAGTCATCGGACTCACCCGATCACAGACGAGCGGTCACCGGAATCGCCCGATCACAG
ACGAGCGGCCACCGGAATCGCCCAATCACAGACAAGCAGTCATCGGAATCACCCGATCACAGACGAGCAGTCATCGGACTCACCCGATCA
CAGACGAGCGGTCACCAGACTCGCCCGATCACAGACGAGCAGTCATCGGAATCACCCGATCACAGACGAGCAGTCATCGGACTCACCCGA
TCACAGACGAGCGGTCACCAGAATCGCCCGATCACAGACGAGCAGTCATCGGAATCACCCGATCACAGACGAGTGGCCACCGGAATCACC
CGATAACAGCCCATCACAACTCCAAAGCCCTTGTGTTGAAAAGGCCGAGGACGAGTGGTCACCAAACAGGGTGGCTCCCCAGGTCCCGAA
GCCTGAGACCCGGAAGGCCCTGGCACCCTTACACCCTCGGACTCCTGCCCTCCTCGGCCTCCCTGGCCCCAGCGCGGCTCCACCCTGGGC
TGCGTCTCCTGGTCACAGGCTGCGTTTCTCCTTTCTGTCCGTGGGCAGCCCAGTCCCCACAGTCACGGCCAAGCCACGCAGAACGAACAT
GACTCCAGAGGACCTCGCCCTGGAGCTGAGCCTGGCGCCGGGTCAGGACGGAGGGAAGGGCGGGTTGGGGTCCGCGGGTCCTCACACCGC
ACGGCAGGCACAGAGGCTCGCCAGGCCCTGATCCGGTCTGTGGGGACGAGGGACACTGAGGAGAGGTGCTGGGCACCAGGACGCTGCCTC
CTGGTCCCTGGTTGGCCTCAGACAAGCACGGCCTCGAGAAAAGAGCCAAGCGCATCGGGAGCACACCAGAAACCGGCCCTGAGCACGAGA
AGAGCCTCCGCCCGGCCCGGGCACCACCCGACCTCGCAGGGAGCAGGCCCTGTCACCGACGGGTCACCTCGCCCACACGGCCAGCACCGA
CTCACCACAGCCCTTCCCAGACCTGGCTGGAGTGGCCGGAGCGGCGGGGCTCATGGCTCCCATCTTGGCCCCTGGAGGTGAGCTCATTCA
CAGAAGTGGTCCCTTCACTCTGAGAGAGAAAATCGTGGCGTGCATCCCAAACCCTAGGCCACGCCTGTGGGTTTCGTGAATGAGATCGAG
GCTGCTGTGGCACCCTGCCCGTCCTGGCCTGGAGCACCCTGGGATCCTGGAGGGAGAGGCCCCACGCCCCCACTCTCCCTCCACACTTCC
AGGGTTGGTGCCCACGAGTTAGAGGCACGCCCTCCCCCAGCGGCCCTCAGGCTTTTCTCAGACATGCGGGAGCCAGGAGAGCACCCTTCT
CCACTCAGCTCCAAAGCGAATCTTTGAAAACACCCACTCGGCTCCCATCTCTGTCACCTAGCCAGGAGGGGTAGCAAAAATAAAGTCACG
AGGACATAGTGGTCACCACTGTCAGTTACAACTTGTCTGTGGAATCCGTAATTGCATCTGTGTGCCGCCTCCGAACACAGAACATTGTTT
GGACGGCAGCCCCACTGCACATAACAGACCCGTGCATCTTCCTCAGTCAGTTTCTGAATATTGTGAATTCAGGCAGGTGTGTGTTCTCTT
CTGCATGTTTTTATGCACTGCCAATTAGCTTCTACTAACCACGGTTCAACAGAAAATAAATGTGTATTTGTGAATAACAAACTGCACAAC
CTGCAAACCAGGAGAGAGGGACAGGTTCTGTCAGGGGTGACACCAGGACACAGGGACAGGTTCTGTCGGGGGTGACACCAGGACACAGGG
ACAGGTTCTGTCATGGGTGACACGAGGACACAGGGACAGGTTCTATCATGGGTGACACCAGGAGAGAGGGACAGGTTCTGTTGGGGGTGA
CAAGAGGAGACAGGGACAGGTTCTGTCGGGGGTGACACCAGGAGAGAGGGACAGGTTCTGTCAGGGGTGACACCAGGAGAGAGGGACAGG
TTCTGTTGGGGGTGACACCAGGACACAGGAATAGGTTCTGTCGGGAGGACAGTGCTGATCGTGTCTCAGCATCAGGAAAGGAGAAAGGCA
GAGGGAGAGCGCTGAGAAGACTGTTCACGCCAGAGTGCTTATTTATTTTTAATTTACTGCTATAGGATAAGCAACCAGGTAGTGTTCCTA
ACAATTAGCGTTACCAAAATTAAAGTTCAAATTATATGTTTAAAATATTGTAGAAGATATATATTTATACTGGACTACTTTTACACCTTC
TAATATCCTGTCCAAGTTTGGGCGCAGATGGTGGAGTTGGGCTGGCATCATGTCCTGTGGCCGCCCCACTTGCCTGTTGGTGCCACTCCA
TCCCGGGCCCCAGGGATGCCAGCTCAGGGCTGACCACAGCAGCCCTGCGTGGGCATCACCTCCTACCCCAGCCCCCATCCTGGGCTGCTG
CGGCCGC

>10230_10230_8_BRD9-TPPP_BRD9_chr5_886707_ENST00000483173_TPPP_chr5_666238_ENST00000360578_length(amino acids)=352AA_BP=1
MNSQDPATTPVTMMTGQTMSERGTKKRKRRRRRSPRRRSIWTMRKEGSERKRRSGSERGSTVTRRERLTTLILGRRWRWSRPQIGQSERA
GHSQPKMRAHLFSNSWNTSSASFRDPHGFFAFPVTDAIAPGYSMIIKHPMDFGTMKDKIVANEYKSVTEFKADFKLMCDNAMTYNRPDTV
YYKLAKKILHAGFKMMSKQAALLGNEDTAVEEPVPEVVPVQVETAKKSKKPSREVIRGKSCRTITFEQFQEALEELAKKRFKDKSSEEAV
REVHRLIEGKAPIISGVTKAISSPTVSRLTDTTKFTGSHKERFDPSGKGKGKAGRVDLVDESGYVSGYKHAGTYDQKVQGGK

--------------------------------------------------------------

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Fusion Gene PPI Analysis for BRD9-TPPP


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for BRD9-TPPP


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for BRD9-TPPP


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneBRD9C0036920Sezary Syndrome1CTD_human
TgeneC3826462Depression in children1PSYGENET