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in Kim Lab

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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:CYP4F12-MYO9B (FusionGDB2 ID:HG66002TG4650)

Fusion Gene Summary for CYP4F12-MYO9B

check button Fusion gene summary
Fusion gene informationFusion gene name: CYP4F12-MYO9B
Fusion gene ID: hg66002tg4650
HgeneTgene
Gene symbol

CYP4F12

MYO9B

Gene ID

66002

4650

Gene namecytochrome P450 family 4 subfamily F member 12myosin IXB
SynonymsCYPIVF12|F22329_1CELIAC4|MYR5
Cytomap('CYP4F12')('MYO9B')

19p13.12

19p13.11

Type of geneprotein-codingprotein-coding
Descriptioncytochrome P450 4F12cytochrome P450, family 4, subfamily F, polypeptide 12cytochrome P450, subfamily IVF, polypeptide 12unconventional myosin-IXbmyosin-IXbunconventional myosin-9b
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000324632, ENST00000550308, 
Fusion gene scores* DoF score3 X 3 X 3=2715 X 18 X 8=2160
# samples 318
** MAII scorelog2(3/27*10)=0.15200309344505
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(18/2160*10)=-3.58496250072116
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CYP4F12 [Title/Abstract] AND MYO9B [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCYP4F12(15807880)-MYO9B(17312948), # samples:1
Anticipated loss of major functional domain due to fusion event.CYP4F12-MYO9B seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
CYP4F12-MYO9B seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
CYP4F12-MYO9B seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
CYP4F12-MYO9B seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneMYO9B

GO:0030048

actin filament-based movement

9490638

TgeneMYO9B

GO:0032011

ARF protein signal transduction

15644318

TgeneMYO9B

GO:0035385

Roundabout signaling pathway

26529257


check buttonFusion gene breakpoints across CYP4F12 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across MYO9B (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BLCATCGA-XF-A9SV-01ACYP4F12chr19

15807880

+MYO9Bchr19

17312948

+


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Fusion Gene ORF analysis for CYP4F12-MYO9B

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000324632ENST00000593411CYP4F12chr19

15807880

+MYO9Bchr19

17312948

+
5CDS-intronENST00000550308ENST00000593411CYP4F12chr19

15807880

+MYO9Bchr19

17312948

+
Frame-shiftENST00000550308ENST00000397274CYP4F12chr19

15807880

+MYO9Bchr19

17312948

+
Frame-shiftENST00000550308ENST00000594824CYP4F12chr19

15807880

+MYO9Bchr19

17312948

+
Frame-shiftENST00000550308ENST00000595618CYP4F12chr19

15807880

+MYO9Bchr19

17312948

+
In-frameENST00000324632ENST00000397274CYP4F12chr19

15807880

+MYO9Bchr19

17312948

+
In-frameENST00000324632ENST00000594824CYP4F12chr19

15807880

+MYO9Bchr19

17312948

+
In-frameENST00000324632ENST00000595618CYP4F12chr19

15807880

+MYO9Bchr19

17312948

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000324632CYP4F12chr1915807880+ENST00000595618MYO9Bchr1917312948+43231524401452470
ENST00000324632CYP4F12chr1915807880+ENST00000594824MYO9Bchr1917312948+4300152415443325593
ENST00000324632CYP4F12chr1915807880+ENST00000397274MYO9Bchr1917312948+43221524401452470

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000324632ENST00000595618CYP4F12chr1915807880+MYO9Bchr1917312948+0.103739230.89626074
ENST00000324632ENST00000594824CYP4F12chr1915807880+MYO9Bchr1917312948+0.0220962840.9779037
ENST00000324632ENST00000397274CYP4F12chr1915807880+MYO9Bchr1917312948+0.1039119960.896088

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Fusion Genomic Features for CYP4F12-MYO9B


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for CYP4F12-MYO9B


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr19:15807880/chr19:17312948)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneMYO9Bchr19:15807880chr19:17312948ENST000003972740391046_107102189.0Coiled coilOntology_term=ECO:0000255
TgeneMYO9Bchr19:15807880chr19:17312948ENST000003972740391880_190102189.0Coiled coilOntology_term=ECO:0000255
TgeneMYO9Bchr19:15807880chr19:17312948ENST000003972740391959_198902189.0Coiled coilOntology_term=ECO:0000255
TgeneMYO9Bchr19:15807880chr19:17312948ENST000005956180401046_107102458.6666666666665Coiled coilOntology_term=ECO:0000255
TgeneMYO9Bchr19:15807880chr19:17312948ENST000005956180401880_190102458.6666666666665Coiled coilOntology_term=ECO:0000255
TgeneMYO9Bchr19:15807880chr19:17312948ENST000005956180401959_198902458.6666666666665Coiled coilOntology_term=ECO:0000255
TgeneMYO9Bchr19:15807880chr19:17312948ENST000003972740391001_102302189.0DomainIQ 3
TgeneMYO9Bchr19:15807880chr19:17312948ENST000003972740391024_105302189.0DomainIQ 4
TgeneMYO9Bchr19:15807880chr19:17312948ENST00000397274039146_95302189.0DomainMyosin motor
TgeneMYO9Bchr19:15807880chr19:17312948ENST0000039727403915_11402189.0DomainRas-associating
TgeneMYO9Bchr19:15807880chr19:17312948ENST000003972740391703_188802189.0DomainRho-GAP
TgeneMYO9Bchr19:15807880chr19:17312948ENST00000397274039957_97702189.0DomainIQ 1
TgeneMYO9Bchr19:15807880chr19:17312948ENST00000397274039979_100002189.0DomainIQ 2
TgeneMYO9Bchr19:15807880chr19:17312948ENST000005956180401001_102302458.6666666666665DomainIQ 3
TgeneMYO9Bchr19:15807880chr19:17312948ENST000005956180401024_105302458.6666666666665DomainIQ 4
TgeneMYO9Bchr19:15807880chr19:17312948ENST00000595618040146_95302458.6666666666665DomainMyosin motor
TgeneMYO9Bchr19:15807880chr19:17312948ENST0000059561804015_11402458.6666666666665DomainRas-associating
TgeneMYO9Bchr19:15807880chr19:17312948ENST000005956180401703_188802458.6666666666665DomainRho-GAP
TgeneMYO9Bchr19:15807880chr19:17312948ENST00000595618040957_97702458.6666666666665DomainIQ 1
TgeneMYO9Bchr19:15807880chr19:17312948ENST00000595618040979_100002458.6666666666665DomainIQ 2
TgeneMYO9Bchr19:15807880chr19:17312948ENST00000397274039239_24602189.0Nucleotide bindingATP
TgeneMYO9Bchr19:15807880chr19:17312948ENST00000595618040239_24602458.6666666666665Nucleotide bindingATP
TgeneMYO9Bchr19:15807880chr19:17312948ENST000003972740391045_215702189.0RegionTail
TgeneMYO9Bchr19:15807880chr19:17312948ENST00000397274039844_85502189.0RegionActin-binding
TgeneMYO9Bchr19:15807880chr19:17312948ENST00000397274039940_104402189.0RegionNeck or regulatory domain
TgeneMYO9Bchr19:15807880chr19:17312948ENST000005956180401045_215702458.6666666666665RegionTail
TgeneMYO9Bchr19:15807880chr19:17312948ENST00000595618040844_85502458.6666666666665RegionActin-binding
TgeneMYO9Bchr19:15807880chr19:17312948ENST00000595618040940_104402458.6666666666665RegionNeck or regulatory domain
TgeneMYO9Bchr19:15807880chr19:17312948ENST000003972740391632_168102189.0Zinc fingerPhorbol-ester/DAG-type
TgeneMYO9Bchr19:15807880chr19:17312948ENST000005956180401632_168102458.6666666666665Zinc fingerPhorbol-ester/DAG-type

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCYP4F12chr19:15807880chr19:17312948ENST00000324632+11219_390525.0TransmembraneHelical
HgeneCYP4F12chr19:15807880chr19:17312948ENST00000324632+11287_1070525.0TransmembraneHelical
HgeneCYP4F12chr19:15807880chr19:17312948ENST00000550308+11319_390525.0TransmembraneHelical
HgeneCYP4F12chr19:15807880chr19:17312948ENST00000550308+11387_1070525.0TransmembraneHelical


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Fusion Gene Sequence for CYP4F12-MYO9B


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>21092_21092_1_CYP4F12-MYO9B_CYP4F12_chr19_15807880_ENST00000324632_MYO9B_chr19_17312948_ENST00000397274_length(transcript)=4322nt_BP=1524nt
AGCTCTTCCCTGGGCCTCAGGTCCTCACCCTGCATCCCCTCTGCCCTGCAGGATGTCGCTGCTGAGCCTGCCCTGGCTGGGCCTCAGACC
GGTGGCAACGTCCCCATGGCTACTCCTGCTGCTGGTTGTGGGCTCCTGGCTACTCGCCCGCATCCTGGCTTGGACCTATGCCTTCTATAA
CAACTGCCGCCGGCTCCAGTGTTTCCCACAGCCCCCAAAACGGAACTGGTTTTGGGGTCACCTGGGCCTGATCACTCCTACAGAGGAGGG
CTTGAAGAACTCGACCCAGATGTCGGCCACCTATTCCCAGGGCTTTACGATATGGCTGGGTCCCATCATCCCCTTCATCGTTTTATGCCA
CCCTGACACCATCCGGTCTATCACCAATGCCTCAGCTGCCATTGCACCCAAGGATAATCTCTTCATCAGGTTCCTGAAGCCCTGGCTGGG
AGAAGGGATACTGCTGAGTGGCGGTGACAAGTGGAGCCGCCACCGTCGGATGCTGACGCCCGCCTTCCATTTCAACATCCTGAAGTCCTA
TATAACGATCTTCAACAAGAGTGCAAACATCATGCTTGACAAGTGGCAGCACCTGGCCTCAGAGGGCAGCAGTTGTCTGGACATGTTTGA
GCACATCAGCCTCATGACCTTGGACAGTCTACAGAAATGCATCTTCAGCTTTGACAGCCATTGTCAGGAGAGGCCCAGTGAATATATTGC
CACCATCTTGGAGCTCAGTGCCCTTGTAGAGAAAAGAAGCCAGCATATCCTCCAGCACATGGACTTTCTGTATTACCTCTCCCATGACGG
GCGGCGCTTCCACAGGGCCTGCCGCCTGGTGCATGACTTCACAGACGCTGTCATCCGGGAGCGGCGTCGCACCCTCCCCACTCAGGGTAT
TGATGATTTTTTCAAAGACAAAGCCAAGTCCAAGACTTTGGATTTCATTGATGTGCTTCTGCTGAGCAAGGATGAAGATGGGAAGGCATT
GTCAGATGAGGATATAAGAGCAGAGGCTGACACCTTCATGTTTGGAGGCCATGACACCACGGCCAGTGGCCTCTCCTGGGTCCTGTACAA
CCTTGCGAGGCACCCAGAATACCAGGAGCGCTGCCGACAGGAGGTGCAAGAGCTTCTGAAGGACCGCGATCCTAAAGAGATTGAATGGGA
CGACCTGGCCCAGCTGCCCTTCCTGACCATGTGCGTGAAGGAGAGCCTGAGGTTACATCCCCCAGCTCCCTTCATCTCCCGATGCTGCAC
CCAGGACATTGTTCTCCCAGATGGCCGAGTCATCCCCAAAGGCATTACCTGCCTCATCGATATTATAGGGGTCCATCACAACCCAACTGT
GTGGCCGGATCCTGAGGTCTACGACCCCTTCCGCTTTGACCCAGAGAACAGCAAGGGGAGGTCACCTCTGGCTTTTATTCCTTTCTCCGC
AGGGCCCAGGTAAGCTTGCAGTGACTTTCTGACCCATCCACCTGTTTTTTTGCAGATTGTCATGAATAAAACGGTGCTGTCACCTCCACG
TGGGCTACAAGGATCTGATGGAGAACTACCAGATCGTCGTCAGCAACCTGGCCACTGAGCGTGGCCAGAAGGACACCAACCTGGTCCTCA
ACCTCTTCCAGTCACTGCTAGATGAGTTCACCCGTGGCTACACCAAGAACGACTTCGAGCCAGTGAAGCAGAGCAAAGCTCAGAAGAAGA
AGCGGAAGCAGGAGCGTGCTGTCCAGGAGCACAACGGGCACGTGTTCGCCAGCTACCAGGTTAGCATCCCGCAGTCGTGCGAGCAGTGCC
TCTCCTATATCTGGCTCATGGACAAGGCCCTGCTCTGCAGCGTGTGCAAGATGACCTGCCACAAGAAGTGCGTGCACAAGATTCAGAGCC
ACTGCTCCTACACCTACGGGAGGAAGGGCGAGCCAGGCGTTGAGCCTGGCCACTTCGGCGTGTGCGTAGACAGCCTGACCAGCGACAAGG
CCTCGGTGCCCATCGTGCTGGAGAAGCTCCTGGAACACGTGGAGATGCACGGCCTGTACACCGAGGGCCTCTACCGCAAGTCGGGTGCTG
CCAACCGCACTCGGGAGCTCCGGCAGGCGCTGCAGACAGACCCCGCAGCAGTCAAGCTGGAGAACTTCCCCATCCACGCCATCACAGGGG
TGCTGAAGCAGTGGCTGCGGGAGCTGCCCGAGCCCCTCATGACCTTCGCACAGTACGGCGACTTCCTCCGAGCCGTCGAGCTGCCGGAGA
AGCAGGAGCAGCTGGCTGCCATCTATGCCGTCCTGGAGCACCTTCCAGAAGCCAACCACAACTCCCTGGAGAGACTCATCTTCCACCTTG
TCAAGGTGGCCCTGCTCGAGGATGTCAACCGCATGTCACCTGGGGCGCTGGCCATTATCTTCGCACCCTGCCTCCTGCGCTGCCCTGACA
ACTCGGACCCGCTGACCAGCATGAAGGACGTCCTCAAGATCACCACGTGCGTGGAGATGCTGATCAAGGAGCAGATGAGGAAATACAAAG
TGAAGATGGAGGAGATCAGCCAACTGGAGGCTGCAGAGAGTATCGCCTTCCGCAGGCTTTCGCTCCTGCGACAAAATGCTCCATGGCCTC
TCAAACTGGGGTTTTCGTCTCCCTATGAGGGGGTCCTGAACAAGAGCCCCAAGACCCGGGACATCCAGGAGGAGGAGCTGGAGGTGCTGC
TGGAGGAGGAGGCAGCCGGCGGCGATGAGGACCGGGAAAAGGAGATTCTCATTGAACGGATCCAGTCCATCAAGGAGGAGAAGGAGGACA
TCACCTACCGGCTGCCGGAGCTGGACCCAAGGGGCTCGGACGAGGAGAACCTGGACTCGGAGACGTCGGCCAGCACCGAGAGCCTGCTGG
AGGAGCGGGCCGGGCGGGGGGCCTCGGAAGGTCAGTATTAAGGGCCCCCTGCGCCTGCTCTCCCTTGCCCCGGCGCGCCCACCCCGAGCC
CCCTCCCCACCGTGGCCGCCCCTCCACGACGAAGGCCGTCGTCCTTCGTAACGGTCAGAGTGAAGACCCCCCGGCGGACCCCCATCATGC
CCACGGCCAACATCAAGCTCCCACCAGGCCTGCCCTCCCACCTGCCTCGCTGGGCACCGGGTGCCCGGGAGGCGGCTGCCCCAGTGCGGC
GCCGGGAGCCACCTGCCCGCCGCCCGGACCAGATACATTCCGTGTACATCACGCCCGGGGCAGACCTGCCAGTGCAGGGCGCCCTGGAGC
CCCTAGAAGAGGATGGCCAGCCACCTGGGGCCAAGCGGAGGTACTCGGATCCCCCAACGTACTGCCTGCCCCCCGCCTCGGGCCAGACCA
ATGGCTGAGAGCCACAGCTGACAAAGTCTGCATGTCCGAGGACGGCCCCTGCACTGGAGCTGGGCGCCAGAGCTGCAGAGCTAGTGTTCG
GCCCTCAGAGAAGGATCCAGAATCAAAAGCTCAAGAGTGACGTGAGGTGGGCACCGGCCCCAAGTGCAGAGTCAAGGCAGGGAGAGGCCG
GCTGGAGCCAGGCCCCCTCGCACGCAGCCCCCAAATCATGGACGCACCTGTGGGGAGCACCACATCTCCACCTGCGGCCTCACATCTCCC
CACTCCCCTTTTTGTACGTTTAACTGTTTCTTTGTACGTGGTTTACGTAACTTTAAACTGTAACAGCCTTAATGGAAGACCAAATGGTTT
TTTATATGTGTATGTACAAAGTTTTCTATTAACGCTGCCCGTCTCCCTTATAACCTGGACGTGAGCTGTCAGAGCAGAAGCCACTAGGCC
ACTGCGCGTCTGAGGCTCAGACCCTGCTGTGGTTGGCTTGGGGTGGCCAATGGGCTGGGACCCTCCATGAGAGTTTTGGACACTTGGGTC
ACCTGACCCGTGCCTCTCTGACACATGTCTCCGGGGGGCAGCCACCTGGCCAATGTGCATTTTTGCACATGCTGGAACCTTCCATGGGGG
TCTGGGCTATTGGCTGGAGCCAGGACATGAGTCAGGGGCACCATGGACCTCACGTGCCAGGGAGACTTGAATGTGGCTGTCACTCTTCCG
GACGCCAAGGGCTGCAGGAGGCTGCTTTTGGCACTACCCACCCCGTGTGACAGAATAGGAGCCAGCGACTCAGGACTGCTCACGGGTCAG
GAGGGCAACGCCTGAAGTCAGACCTCCCTATAGGTCAACAGGGACAACCTGGGGATCTCTGGAGCAGGGCCCTCCTCTCTCAGGCTTGGC
CCACTCCCCCAGACACCTGGACACGTGGCCACAAATCTGGGACAAGGGGCCCCCGCACAGCATGAAATAAAAAGTGCCTGAGAAGTGTGT

>21092_21092_1_CYP4F12-MYO9B_CYP4F12_chr19_15807880_ENST00000324632_MYO9B_chr19_17312948_ENST00000397274_length(amino acids)=470AA_BP=
MPCRMSLLSLPWLGLRPVATSPWLLLLLVVGSWLLARILAWTYAFYNNCRRLQCFPQPPKRNWFWGHLGLITPTEEGLKNSTQMSATYSQ
GFTIWLGPIIPFIVLCHPDTIRSITNASAAIAPKDNLFIRFLKPWLGEGILLSGGDKWSRHRRMLTPAFHFNILKSYITIFNKSANIMLD
KWQHLASEGSSCLDMFEHISLMTLDSLQKCIFSFDSHCQERPSEYIATILELSALVEKRSQHILQHMDFLYYLSHDGRRFHRACRLVHDF
TDAVIRERRRTLPTQGIDDFFKDKAKSKTLDFIDVLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQ
EVQELLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLPDGRVIPKGITCLIDIIGVHHNPTVWPDPEVYDPFRFD

--------------------------------------------------------------
>21092_21092_2_CYP4F12-MYO9B_CYP4F12_chr19_15807880_ENST00000324632_MYO9B_chr19_17312948_ENST00000594824_length(transcript)=4300nt_BP=1524nt
AGCTCTTCCCTGGGCCTCAGGTCCTCACCCTGCATCCCCTCTGCCCTGCAGGATGTCGCTGCTGAGCCTGCCCTGGCTGGGCCTCAGACC
GGTGGCAACGTCCCCATGGCTACTCCTGCTGCTGGTTGTGGGCTCCTGGCTACTCGCCCGCATCCTGGCTTGGACCTATGCCTTCTATAA
CAACTGCCGCCGGCTCCAGTGTTTCCCACAGCCCCCAAAACGGAACTGGTTTTGGGGTCACCTGGGCCTGATCACTCCTACAGAGGAGGG
CTTGAAGAACTCGACCCAGATGTCGGCCACCTATTCCCAGGGCTTTACGATATGGCTGGGTCCCATCATCCCCTTCATCGTTTTATGCCA
CCCTGACACCATCCGGTCTATCACCAATGCCTCAGCTGCCATTGCACCCAAGGATAATCTCTTCATCAGGTTCCTGAAGCCCTGGCTGGG
AGAAGGGATACTGCTGAGTGGCGGTGACAAGTGGAGCCGCCACCGTCGGATGCTGACGCCCGCCTTCCATTTCAACATCCTGAAGTCCTA
TATAACGATCTTCAACAAGAGTGCAAACATCATGCTTGACAAGTGGCAGCACCTGGCCTCAGAGGGCAGCAGTTGTCTGGACATGTTTGA
GCACATCAGCCTCATGACCTTGGACAGTCTACAGAAATGCATCTTCAGCTTTGACAGCCATTGTCAGGAGAGGCCCAGTGAATATATTGC
CACCATCTTGGAGCTCAGTGCCCTTGTAGAGAAAAGAAGCCAGCATATCCTCCAGCACATGGACTTTCTGTATTACCTCTCCCATGACGG
GCGGCGCTTCCACAGGGCCTGCCGCCTGGTGCATGACTTCACAGACGCTGTCATCCGGGAGCGGCGTCGCACCCTCCCCACTCAGGGTAT
TGATGATTTTTTCAAAGACAAAGCCAAGTCCAAGACTTTGGATTTCATTGATGTGCTTCTGCTGAGCAAGGATGAAGATGGGAAGGCATT
GTCAGATGAGGATATAAGAGCAGAGGCTGACACCTTCATGTTTGGAGGCCATGACACCACGGCCAGTGGCCTCTCCTGGGTCCTGTACAA
CCTTGCGAGGCACCCAGAATACCAGGAGCGCTGCCGACAGGAGGTGCAAGAGCTTCTGAAGGACCGCGATCCTAAAGAGATTGAATGGGA
CGACCTGGCCCAGCTGCCCTTCCTGACCATGTGCGTGAAGGAGAGCCTGAGGTTACATCCCCCAGCTCCCTTCATCTCCCGATGCTGCAC
CCAGGACATTGTTCTCCCAGATGGCCGAGTCATCCCCAAAGGCATTACCTGCCTCATCGATATTATAGGGGTCCATCACAACCCAACTGT
GTGGCCGGATCCTGAGGTCTACGACCCCTTCCGCTTTGACCCAGAGAACAGCAAGGGGAGGTCACCTCTGGCTTTTATTCCTTTCTCCGC
AGGGCCCAGGTAAGCTTGCAGTGACTTTCTGACCCATCCACCTGTTTTTTTGCAGATTGTCATGAATAAAACGGTGCTGTCACCTCCACG
TGGGCTACAAGGATCTGATGGAGAACTACCAGATCGTCGTCAGCAACCTGGCCACTGAGCGTGGCCAGAAGGACACCAACCTGGTCCTCA
ACCTCTTCCAGTCACTGCTAGATGAGTTCACCCGTGGCTACACCAAGAACGACTTCGAGCCAGTGAAGCAGAGCAAAGCTCAGAAGAAGA
AGCGGAAGCAGGAGCGTGCTGTCCAGGAGCACAACGGGCACGTGTTCGCCAGCTACCAGGTTAGCATCCCGCAGTCGTGCGAGCAGTGCC
TCTCCTATATCTGGCTCATGGACAAGGCCCTGCTCTGCAGCGTGTGCAAGATGACCTGCCACAAGAAGTGCGTGCACAAGATTCAGAGCC
ACTGCTCCTACACCTACGGGAGGAAGGGCGAGCCAGGCGTTGAGCCTGGCCACTTCGGCGTGTGCGTAGACAGCCTGACCAGCGACAAGG
CCTCGGTGCCCATCGTGCTGGAGAAGCTCCTGGAACACGTGGAGATGCACGGCCTGTACACCGAGGGCCTCTACCGCAAGTCGGGTGCTG
CCAACCGCACTCGGGAGCTCCGGCAGGCGCTGCAGACAGACCCCGCAGCAGTCAAGCTGGAGAACTTCCCCATCCACGCCATCACAGGGG
TGCTGAAGCAGTGGCTGCGGGAGCTGCCCGAGCCCCTCATGACCTTCGCACAGTACGGCGACTTCCTCCGAGCCGTCGAGCTGCCGGAGA
AGCAGGAGCAGCTGGCTGCCATCTATGCCGTCCTGGAGCACCTTCCAGAAGCCAACCACAACTCCCTGGAGAGACTCATCTTCCACCTTG
TCAAGGTGGCCCTGCTCGAGGATGTCAACCGCATGTCACCTGGGGCGCTGGCCATTATCTTCGCACCCTGCCTCCTGCGCTGCCCTGACA
ACTCGGACCCGCTGACCAGCATGAAGGACGTCCTCAAGATCACCACGTGCGTGGAGATGCTGATCAAGGAGCAGATGAGGAAATACAAAG
TGAAGATGGAGGAGATCAGCCAACTGGAGGCTGCAGAGAGTATCGCCTTCCGCAGGCTTTCGCTCCTGCGACAAAATGCTCCATGGCCTC
TCAAACTGGGGTTTTCGTCTCCCTATGAGGGGGTCCTGAACAAGAGCCCCAAGACCCGGGACATCCAGGAGGAGGAGCTGGAGGTGCTGC
TGGAGGAGGAGGCAGCCGGCGGCGATGAGGACCGGGAAAAGGAGATTCTCATTGAACGGATCCAGTCCATCAAGGAGGAGAAGCAAGACA
TCACCTACCGGCTGCCGGAGCTGGACCCAAGGGGCTCGGACGAGGAGAACCTGGACTCGGAGACGTCGGCCAGCACCGAGAGCCTGCTGG
AGGAGCGGGCCGGGCGGGGGGCCTCGGAAGGGCCCCCTGCGCCTGCTCTCCCTTGCCCCGGCGCGCCCACCCCGAGCCCCCTCCCCACCG
TGGCCGCCCCTCCACGACGAAGGCCGTCGTCCTTCGTAACGGTCAGAGTGAAGACCCCCCGGCGGACCCCCATCATGCCCACGGCCAACA
TCAAGCTCCCACCAGGCCTGCCCTCCCACCTGCCTCGCTGGGCACCGGGTGCCCGGGAGGCGGCTGCCCCAGTGCGGCGCCGGGAGCCAC
CTGCCCGCCGCCCGGACCAGATACATTCCGTGTACATCACGCCCGGGGCAGACCTGCCAGTGCAGGGCGCCCTGGAGCCCCTAGAAGAGG
ATGGCCAGCCACCTGGGGCCAAGCGGAGGTACTCGGATCCCCCAACGTACTGCCTGCCCCCCGCCTCGGGCCAGACCAATGGCTGAGAGC
CACAGCTGACAAAGTCTGCATGTCCGAGGACGGCCCCTGCACTGGAGCTGGGCGCCAGAGCTGCAGAGCTAGTGTTCGGCCCTCAGAGAA
GGATCCAGAATCAAAAGCTCAAGAGTGACGTGAGGTGGGCACCGGCCCCAAGTGCAGAGTCAAGGCAGGGAGAGGCCGGCTGGAGCCAGG
CCCCCTCGCACGCAGCCCCCAAATCATGGACGCACCTGTGGGGAGCACCACATCTCCACCTGCGGCCTCACATCTCCCCACTCCCCTTTT
TGTACGTTTAACTGTTTCTTTGTACGTGGTTTACGTAACTTTAAACTGTAACAGCCTTAATGGAAGACCAAATGGTTTTTTATATGTGTA
TGTACAAAGTTTTCTATTAACGCTGCCCGTCTCCCTTATAACCTGGACGTGAGCTGTCAGAGCAGAAGCCACTAGGCCACTGCGCGTCTG
AGGCTCAGACCCTGCTGTGGTTGGCTTGGGGTGGCCAATGGGCTGGGACCCTCCATGAGAGTTTTGGACACTTGGGTCACCTGACCCGTG
CCTCTCTGACACATGTCTCCGGGGGGCAGCCACCTGGCCAATGTGCATTTTTGCACATGCTGGAACCTTCCATGGGGGTCTGGGCTATTG
GCTGGAGCCAGGACATGAGTCAGGGGCACCATGGACCTCACGTGCCAGGGAGACTTGAATGTGGCTGTCACTCTTCCGGACGCCAAGGGC
TGCAGGAGGCTGCTTTTGGCACTACCCACCCCGTGTGACAGAATAGGAGCCAGCGACTCAGGACTGCTCACGGGTCAGGAGGGCAACGCC
TGAAGTCAGACCTCCCTATAGGTCAACAGGGACAACCTGGGGATCTCTGGAGCAGGGCCCTCCTCTCTCAGGCTTGGCCCACTCCCCCAG

>21092_21092_2_CYP4F12-MYO9B_CYP4F12_chr19_15807880_ENST00000324632_MYO9B_chr19_17312948_ENST00000594824_length(amino acids)=593AA_BP=
MMENYQIVVSNLATERGQKDTNLVLNLFQSLLDEFTRGYTKNDFEPVKQSKAQKKKRKQERAVQEHNGHVFASYQVSIPQSCEQCLSYIW
LMDKALLCSVCKMTCHKKCVHKIQSHCSYTYGRKGEPGVEPGHFGVCVDSLTSDKASVPIVLEKLLEHVEMHGLYTEGLYRKSGAANRTR
ELRQALQTDPAAVKLENFPIHAITGVLKQWLRELPEPLMTFAQYGDFLRAVELPEKQEQLAAIYAVLEHLPEANHNSLERLIFHLVKVAL
LEDVNRMSPGALAIIFAPCLLRCPDNSDPLTSMKDVLKITTCVEMLIKEQMRKYKVKMEEISQLEAAESIAFRRLSLLRQNAPWPLKLGF
SSPYEGVLNKSPKTRDIQEEELEVLLEEEAAGGDEDREKEILIERIQSIKEEKQDITYRLPELDPRGSDEENLDSETSASTESLLEERAG
RGASEGPPAPALPCPGAPTPSPLPTVAAPPRRRPSSFVTVRVKTPRRTPIMPTANIKLPPGLPSHLPRWAPGAREAAAPVRRREPPARRP

--------------------------------------------------------------
>21092_21092_3_CYP4F12-MYO9B_CYP4F12_chr19_15807880_ENST00000324632_MYO9B_chr19_17312948_ENST00000595618_length(transcript)=4323nt_BP=1524nt
AGCTCTTCCCTGGGCCTCAGGTCCTCACCCTGCATCCCCTCTGCCCTGCAGGATGTCGCTGCTGAGCCTGCCCTGGCTGGGCCTCAGACC
GGTGGCAACGTCCCCATGGCTACTCCTGCTGCTGGTTGTGGGCTCCTGGCTACTCGCCCGCATCCTGGCTTGGACCTATGCCTTCTATAA
CAACTGCCGCCGGCTCCAGTGTTTCCCACAGCCCCCAAAACGGAACTGGTTTTGGGGTCACCTGGGCCTGATCACTCCTACAGAGGAGGG
CTTGAAGAACTCGACCCAGATGTCGGCCACCTATTCCCAGGGCTTTACGATATGGCTGGGTCCCATCATCCCCTTCATCGTTTTATGCCA
CCCTGACACCATCCGGTCTATCACCAATGCCTCAGCTGCCATTGCACCCAAGGATAATCTCTTCATCAGGTTCCTGAAGCCCTGGCTGGG
AGAAGGGATACTGCTGAGTGGCGGTGACAAGTGGAGCCGCCACCGTCGGATGCTGACGCCCGCCTTCCATTTCAACATCCTGAAGTCCTA
TATAACGATCTTCAACAAGAGTGCAAACATCATGCTTGACAAGTGGCAGCACCTGGCCTCAGAGGGCAGCAGTTGTCTGGACATGTTTGA
GCACATCAGCCTCATGACCTTGGACAGTCTACAGAAATGCATCTTCAGCTTTGACAGCCATTGTCAGGAGAGGCCCAGTGAATATATTGC
CACCATCTTGGAGCTCAGTGCCCTTGTAGAGAAAAGAAGCCAGCATATCCTCCAGCACATGGACTTTCTGTATTACCTCTCCCATGACGG
GCGGCGCTTCCACAGGGCCTGCCGCCTGGTGCATGACTTCACAGACGCTGTCATCCGGGAGCGGCGTCGCACCCTCCCCACTCAGGGTAT
TGATGATTTTTTCAAAGACAAAGCCAAGTCCAAGACTTTGGATTTCATTGATGTGCTTCTGCTGAGCAAGGATGAAGATGGGAAGGCATT
GTCAGATGAGGATATAAGAGCAGAGGCTGACACCTTCATGTTTGGAGGCCATGACACCACGGCCAGTGGCCTCTCCTGGGTCCTGTACAA
CCTTGCGAGGCACCCAGAATACCAGGAGCGCTGCCGACAGGAGGTGCAAGAGCTTCTGAAGGACCGCGATCCTAAAGAGATTGAATGGGA
CGACCTGGCCCAGCTGCCCTTCCTGACCATGTGCGTGAAGGAGAGCCTGAGGTTACATCCCCCAGCTCCCTTCATCTCCCGATGCTGCAC
CCAGGACATTGTTCTCCCAGATGGCCGAGTCATCCCCAAAGGCATTACCTGCCTCATCGATATTATAGGGGTCCATCACAACCCAACTGT
GTGGCCGGATCCTGAGGTCTACGACCCCTTCCGCTTTGACCCAGAGAACAGCAAGGGGAGGTCACCTCTGGCTTTTATTCCTTTCTCCGC
AGGGCCCAGGTAAGCTTGCAGTGACTTTCTGACCCATCCACCTGTTTTTTTGCAGATTGTCATGAATAAAACGGTGCTGTCACCTCCACG
TGGGCTACAAGGATCTGATGGAGAACTACCAGATCGTCGTCAGCAACCTGGCCACTGAGCGTGGCCAGAAGGACACCAACCTGGTCCTCA
ACCTCTTCCAGTCACTGCTAGATGAGTTCACCCGTGGCTACACCAAGAACGACTTCGAGCCAGTGAAGCAGAGCAAAGCTCAGAAGAAGA
AGCGGAAGCAGGAGCGTGCTGTCCAGGAGCACAACGGGCACGTGTTCGCCAGCTACCAGGTTAGCATCCCGCAGTCGTGCGAGCAGTGCC
TCTCCTATATCTGGCTCATGGACAAGGCCCTGCTCTGCAGCGTGTGCAAGATGACCTGCCACAAGAAGTGCGTGCACAAGATTCAGAGCC
ACTGCTCCTACACCTACGGGAGGAAGGGCGAGCCAGGCGTTGAGCCTGGCCACTTCGGCGTGTGCGTAGACAGCCTGACCAGCGACAAGG
CCTCGGTGCCCATCGTGCTGGAGAAGCTCCTGGAACACGTGGAGATGCACGGCCTGTACACCGAGGGCCTCTACCGCAAGTCGGGTGCTG
CCAACCGCACTCGGGAGCTCCGGCAGGCGCTGCAGACAGACCCCGCAGCAGTCAAGCTGGAGAACTTCCCCATCCACGCCATCACAGGGG
TGCTGAAGCAGTGGCTGCGGGAGCTGCCCGAGCCCCTCATGACCTTCGCACAGTACGGCGACTTCCTCCGAGCCGTCGAGCTGCCGGAGA
AGCAGGAGCAGCTGGCTGCCATCTATGCCGTCCTGGAGCACCTTCCAGAAGCCAACCACAACTCCCTGGAGAGACTCATCTTCCACCTTG
TCAAGGTGGCCCTGCTCGAGGATGTCAACCGCATGTCACCTGGGGCGCTGGCCATTATCTTCGCACCCTGCCTCCTGCGCTGCCCTGACA
ACTCGGACCCGCTGACCAGCATGAAGGACGTCCTCAAGATCACCACGTGCGTGGAGATGCTGATCAAGGAGCAGATGAGGAAATACAAAG
TGAAGATGGAGGAGATCAGCCAACTGGAGGCTGCAGAGAGTATCGCCTTCCGCAGGCTTTCGCTCCTGCGACAAAATGCTCCATGGCCTC
TCAAACTGGGGTTTTCGTCTCCCTATGAGGGGGTCCTGAACAAGAGCCCCAAGACCCGGGACATCCAGGAGGAGGAGCTGGAGGTGCTGC
TGGAGGAGGAGGCAGCCGGCGGCGATGAGGACCGGGAAAAGGAGATTCTCATTGAACGGATCCAGTCCATCAAGGAGGAGAAGGAGGACA
TCACCTACCGGCTGCCGGAGCTGGACCCAAGGGGCTCGGACGAGGAGAACCTGGACTCGGAGACGTCGGCCAGCACCGAGAGCCTGCTGG
AGGAGCGGGCCGGGCGGGGGGCCTCGGAAGGTCAGTATTAAGGGCCCCCTGCGCCTGCTCTCCCTTGCCCCGGCGCGCCCACCCCGAGCC
CCCTCCCCACCGTGGCCGCCCCTCCACGACGAAGGCCGTCGTCCTTCGTAACGGTCAGAGTGAAGACCCCCCGGCGGACCCCCATCATGC
CCACGGCCAACATCAAGCTCCCACCAGGCCTGCCCTCCCACCTGCCTCGCTGGGCACCGGGTGCCCGGGAGGCGGCTGCCCCAGTGCGGC
GCCGGGAGCCACCTGCCCGCCGCCCGGACCAGATACATTCCGTGTACATCACGCCCGGGGCAGACCTGCCAGTGCAGGGCGCCCTGGAGC
CCCTAGAAGAGGATGGCCAGCCACCTGGGGCCAAGCGGAGGTACTCGGATCCCCCAACGTACTGCCTGCCCCCCGCCTCGGGCCAGACCA
ATGGCTGAGAGCCACAGCTGACAAAGTCTGCATGTCCGAGGACGGCCCCTGCACTGGAGCTGGGCGCCAGAGCTGCAGAGCTAGTGTTCG
GCCCTCAGAGAAGGATCCAGAATCAAAAGCTCAAGAGTGACGTGAGGTGGGCACCGGCCCCAAGTGCAGAGTCAAGGCAGGGAGAGGCCG
GCTGGAGCCAGGCCCCCTCGCACGCAGCCCCCAAATCATGGACGCACCTGTGGGGAGCACCACATCTCCACCTGCGGCCTCACATCTCCC
CACTCCCCTTTTTGTACGTTTAACTGTTTCTTTGTACGTGGTTTACGTAACTTTAAACTGTAACAGCCTTAATGGAAGACCAAATGGTTT
TTTATATGTGTATGTACAAAGTTTTCTATTAACGCTGCCCGTCTCCCTTATAACCTGGACGTGAGCTGTCAGAGCAGAAGCCACTAGGCC
ACTGCGCGTCTGAGGCTCAGACCCTGCTGTGGTTGGCTTGGGGTGGCCAATGGGCTGGGACCCTCCATGAGAGTTTTGGACACTTGGGTC
ACCTGACCCGTGCCTCTCTGACACATGTCTCCGGGGGGCAGCCACCTGGCCAATGTGCATTTTTGCACATGCTGGAACCTTCCATGGGGG
TCTGGGCTATTGGCTGGAGCCAGGACATGAGTCAGGGGCACCATGGACCTCACGTGCCAGGGAGACTTGAATGTGGCTGTCACTCTTCCG
GACGCCAAGGGCTGCAGGAGGCTGCTTTTGGCACTACCCACCCCGTGTGACAGAATAGGAGCCAGCGACTCAGGACTGCTCACGGGTCAG
GAGGGCAACGCCTGAAGTCAGACCTCCCTATAGGTCAACAGGGACAACCTGGGGATCTCTGGAGCAGGGCCCTCCTCTCTCAGGCTTGGC
CCACTCCCCCAGACACCTGGACACGTGGCCACAAATCTGGGACAAGGGGCCCCCGCACAGCATGAAATAAAAAGTGCCTGAGAAGTGTGT

>21092_21092_3_CYP4F12-MYO9B_CYP4F12_chr19_15807880_ENST00000324632_MYO9B_chr19_17312948_ENST00000595618_length(amino acids)=470AA_BP=
MPCRMSLLSLPWLGLRPVATSPWLLLLLVVGSWLLARILAWTYAFYNNCRRLQCFPQPPKRNWFWGHLGLITPTEEGLKNSTQMSATYSQ
GFTIWLGPIIPFIVLCHPDTIRSITNASAAIAPKDNLFIRFLKPWLGEGILLSGGDKWSRHRRMLTPAFHFNILKSYITIFNKSANIMLD
KWQHLASEGSSCLDMFEHISLMTLDSLQKCIFSFDSHCQERPSEYIATILELSALVEKRSQHILQHMDFLYYLSHDGRRFHRACRLVHDF
TDAVIRERRRTLPTQGIDDFFKDKAKSKTLDFIDVLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQ
EVQELLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLPDGRVIPKGITCLIDIIGVHHNPTVWPDPEVYDPFRFD

--------------------------------------------------------------

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Fusion Gene PPI Analysis for CYP4F12-MYO9B


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneMYO9Bchr19:15807880chr19:17312948ENST000003972740391739_174402189.0RHOA
TgeneMYO9Bchr19:15807880chr19:17312948ENST000005956180401739_174402458.6666666666665RHOA


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CYP4F12-MYO9B


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CYP4F12-MYO9B


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneC0036341Schizophrenia3PSYGENET
TgeneC0007570Celiac Disease1CTD_human;GENOMICS_ENGLAND
TgeneC2931456Prostate cancer, familial1CTD_human
TgeneC4722327PROSTATE CANCER, HEREDITARY, 11CTD_human