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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:BRAF-MACF1 (FusionGDB2 ID:HG673TG23499)

Fusion Gene Summary for BRAF-MACF1

check button Fusion gene summary
Fusion gene informationFusion gene name: BRAF-MACF1
Fusion gene ID: hg673tg23499
HgeneTgene
Gene symbol

BRAF

MACF1

Gene ID

673

23499

Gene nameB-Raf proto-oncogene, serine/threonine kinasemicrotubule actin crosslinking factor 1
SynonymsB-RAF1|B-raf|BRAF1|NS7|RAFB1ABP620|ACF7|LIS9|MACF|OFC4
Cytomap('BRAF')('MACF1')

7q34

1p34.3

Type of geneprotein-codingprotein-coding
Descriptionserine/threonine-protein kinase B-raf94 kDa B-raf proteinB-Raf proto-oncogene serine/threonine-protein kinase (p94)B-Raf serine/threonine-proteinmurine sarcoma viral (v-raf) oncogene homolog B1proto-oncogene B-Rafv-raf murine sarcoma viral oncogene microtubule-actin cross-linking factor 1620 kDa actin binding proteinactin cross-linking family protein 7macrophin 1 isoformtrabeculin-alpha
Modification date2020032920200313
UniProtAcc

P15056

.
Ensembl transtripts involved in fusion geneENST00000288602, ENST00000288602, 
Fusion gene scores* DoF score28 X 21 X 11=646824 X 23 X 9=4968
# samples 3224
** MAII scorelog2(32/6468*10)=-4.3371758685863
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(24/4968*10)=-4.37155886261196
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: BRAF [Title/Abstract] AND MACF1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointBRAF(140494108)-MACF1(39898207), # samples:3
Anticipated loss of major functional domain due to fusion event.BRAF-MACF1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
BRAF-MACF1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
BRAF-MACF1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
BRAF-MACF1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
MACF1-BRAF seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
MACF1-BRAF seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneBRAF

GO:0000186

activation of MAPKK activity

29433126

HgeneBRAF

GO:0006468

protein phosphorylation

17563371

HgeneBRAF

GO:0010828

positive regulation of glucose transmembrane transport

23010278

HgeneBRAF

GO:0033138

positive regulation of peptidyl-serine phosphorylation

19667065

HgeneBRAF

GO:0043066

negative regulation of apoptotic process

19667065

HgeneBRAF

GO:0070374

positive regulation of ERK1 and ERK2 cascade

22065586

HgeneBRAF

GO:0071277

cellular response to calcium ion

18567582

HgeneBRAF

GO:0090150

establishment of protein localization to membrane

23010278

TgeneMACF1

GO:0030334

regulation of cell migration

27693509

TgeneMACF1

GO:0043001

Golgi to plasma membrane protein transport

15265687

TgeneMACF1

GO:0045773

positive regulation of axon extension

22705394

TgeneMACF1

GO:0051893

regulation of focal adhesion assembly

27693509


check buttonFusion gene breakpoints across BRAF (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across MACF1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4THCATCGA-DE-A0Y2-01ABRAFchr7

140494108

-MACF1chr1

39898207

+


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Fusion Gene ORF analysis for BRAF-MACF1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000288602ENST00000476350BRAFchr7

140494108

-MACF1chr1

39898207

+
5CDS-intronENST00000288602ENST00000484793BRAFchr7

140494108

-MACF1chr1

39898207

+
5CDS-intronENST00000288602ENST00000536367BRAFchr7

140494108

-MACF1chr1

39898207

+
5CDS-intronENST00000288602ENST00000602421BRAFchr7

140494108

-MACF1chr1

39898207

+
In-frameENST00000288602ENST00000289893BRAFchr7

140494108

-MACF1chr1

39898207

+
In-frameENST00000288602ENST00000317713BRAFchr7

140494108

-MACF1chr1

39898207

+
In-frameENST00000288602ENST00000361689BRAFchr7

140494108

-MACF1chr1

39898207

+
In-frameENST00000288602ENST00000372915BRAFchr7

140494108

-MACF1chr1

39898207

+
In-frameENST00000288602ENST00000539005BRAFchr7

140494108

-MACF1chr1

39898207

+
In-frameENST00000288602ENST00000545844BRAFchr7

140494108

-MACF1chr1

39898207

+
In-frameENST00000288602ENST00000564288BRAFchr7

140494108

-MACF1chr1

39898207

+
In-frameENST00000288602ENST00000567887BRAFchr7

140494108

-MACF1chr1

39898207

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000288602BRAFchr7140494108-ENST00000545844MACF1chr139898207+766612016163422093
ENST00000288602BRAFchr7140494108-ENST00000567887MACF1chr139898207+791512016165312156
ENST00000288602BRAFchr7140494108-ENST00000372915MACF1chr139898207+752912016163422093
ENST00000288602BRAFchr7140494108-ENST00000361689MACF1chr139898207+753612016163422093
ENST00000288602BRAFchr7140494108-ENST00000539005MACF1chr139898207+766612016163422093
ENST00000288602BRAFchr7140494108-ENST00000317713MACF1chr139898207+766612016163422093
ENST00000288602BRAFchr7140494108-ENST00000564288MACF1chr139898207+791512016165312156
ENST00000288602BRAFchr7140494108-ENST00000289893MACF1chr139898207+755412016163602099

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000288602ENST00000545844BRAFchr7140494108-MACF1chr139898207+0.0009140550.9990859
ENST00000288602ENST00000567887BRAFchr7140494108-MACF1chr139898207+0.0008961310.99910384
ENST00000288602ENST00000372915BRAFchr7140494108-MACF1chr139898207+0.0010052090.99899477
ENST00000288602ENST00000361689BRAFchr7140494108-MACF1chr139898207+0.0009903660.9990096
ENST00000288602ENST00000539005BRAFchr7140494108-MACF1chr139898207+0.0009204540.9990796
ENST00000288602ENST00000317713BRAFchr7140494108-MACF1chr139898207+0.0009204540.9990796
ENST00000288602ENST00000564288BRAFchr7140494108-MACF1chr139898207+0.0008961310.99910384
ENST00000288602ENST00000289893BRAFchr7140494108-MACF1chr139898207+0.000892090.9991079

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Fusion Genomic Features for BRAF-MACF1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
BRAFchr7140494107-MACF1chr139898206+8.59E-101
BRAFchr7140494107-MACF1chr139898206+8.59E-101

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for BRAF-MACF1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr7:140494108/chr1:39898207)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
BRAF

P15056

.
FUNCTION: Protein kinase involved in the transduction of mitogenic signals from the cell membrane to the nucleus (Probable). Phosphorylates MAP2K1, and thereby activates the MAP kinase signal transduction pathway (PubMed:21441910, PubMed:29433126). May play a role in the postsynaptic responses of hippocampal neurons (PubMed:1508179). {ECO:0000269|PubMed:1508179, ECO:0000269|PubMed:21441910, ECO:0000269|PubMed:29433126, ECO:0000305}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneBRAFchr7:140494108chr1:39898207ENST00000288602-818122_129380767.0Compositional biasNote=Poly-Ser
HgeneBRAFchr7:140494108chr1:39898207ENST00000288602-8186_11380767.0Compositional biasNote=Poly-Gly
HgeneBRAFchr7:140494108chr1:39898207ENST00000288602-818155_227380767.0DomainRBD
HgeneBRAFchr7:140494108chr1:39898207ENST00000288602-818234_280380767.0Zinc fingerPhorbol-ester/DAG-type
TgeneMACF1chr7:140494108chr1:39898207ENST0000028989329647054_706542195939.0Calcium binding1
TgeneMACF1chr7:140494108chr1:39898207ENST0000028989329647090_710142195939.0Calcium binding2
TgeneMACF1chr7:140494108chr1:39898207ENST0000036168959937054_706537175431.0Calcium binding1
TgeneMACF1chr7:140494108chr1:39898207ENST0000036168959937090_710137175431.0Calcium binding2
TgeneMACF1chr7:140494108chr1:39898207ENST0000037291563977054_706556757389.0Calcium binding1
TgeneMACF1chr7:140494108chr1:39898207ENST0000037291563977090_710156757389.0Calcium binding2
TgeneMACF1chr7:140494108chr1:39898207ENST0000054584460947054_706537175431.0Calcium binding1
TgeneMACF1chr7:140494108chr1:39898207ENST0000054584460947090_710137175431.0Calcium binding2
TgeneMACF1chr7:140494108chr1:39898207ENST0000028989329647222_735142195939.0Compositional biasNote=Ser-rich
TgeneMACF1chr7:140494108chr1:39898207ENST0000036168959937222_735137175431.0Compositional biasNote=Ser-rich
TgeneMACF1chr7:140494108chr1:39898207ENST0000037291563977222_735156757389.0Compositional biasNote=Ser-rich
TgeneMACF1chr7:140494108chr1:39898207ENST0000054584460947222_735137175431.0Compositional biasNote=Ser-rich
TgeneMACF1chr7:140494108chr1:39898207ENST0000028989329647041_707642195939.0DomainEF-hand 1
TgeneMACF1chr7:140494108chr1:39898207ENST0000028989329647077_711242195939.0DomainEF-hand 2
TgeneMACF1chr7:140494108chr1:39898207ENST0000028989329647117_718942195939.0DomainGAR
TgeneMACF1chr7:140494108chr1:39898207ENST0000036168959937041_707637175431.0DomainEF-hand 1
TgeneMACF1chr7:140494108chr1:39898207ENST0000036168959937077_711237175431.0DomainEF-hand 2
TgeneMACF1chr7:140494108chr1:39898207ENST0000036168959937117_718937175431.0DomainGAR
TgeneMACF1chr7:140494108chr1:39898207ENST0000037291563977041_707656757389.0DomainEF-hand 1
TgeneMACF1chr7:140494108chr1:39898207ENST0000037291563977077_711256757389.0DomainEF-hand 2
TgeneMACF1chr7:140494108chr1:39898207ENST0000037291563977117_718956757389.0DomainGAR
TgeneMACF1chr7:140494108chr1:39898207ENST0000054584460947041_707637175431.0DomainEF-hand 1
TgeneMACF1chr7:140494108chr1:39898207ENST0000054584460947077_711237175431.0DomainEF-hand 2
TgeneMACF1chr7:140494108chr1:39898207ENST0000054584460947117_718937175431.0DomainGAR
TgeneMACF1chr7:140494108chr1:39898207ENST0000028989329647117_738842195939.0RegionC-terminal tail
TgeneMACF1chr7:140494108chr1:39898207ENST0000028989329647313_732842195939.0RegionNote=4 X 4 AA tandem repeats of [GS]-S-R-[AR]
TgeneMACF1chr7:140494108chr1:39898207ENST0000036168959937117_738837175431.0RegionC-terminal tail
TgeneMACF1chr7:140494108chr1:39898207ENST0000036168959937313_732837175431.0RegionNote=4 X 4 AA tandem repeats of [GS]-S-R-[AR]
TgeneMACF1chr7:140494108chr1:39898207ENST0000037291563977117_738856757389.0RegionC-terminal tail
TgeneMACF1chr7:140494108chr1:39898207ENST0000037291563977313_732856757389.0RegionNote=4 X 4 AA tandem repeats of [GS]-S-R-[AR]
TgeneMACF1chr7:140494108chr1:39898207ENST0000054584460947117_738837175431.0RegionC-terminal tail
TgeneMACF1chr7:140494108chr1:39898207ENST0000054584460947313_732837175431.0RegionNote=4 X 4 AA tandem repeats of [GS]-S-R-[AR]
TgeneMACF1chr7:140494108chr1:39898207ENST0000028989329644261_428742195939.0RepeatNote=LRR 15
TgeneMACF1chr7:140494108chr1:39898207ENST0000028989329644466_457442195939.0RepeatNote=Spectrin 3
TgeneMACF1chr7:140494108chr1:39898207ENST0000028989329644511_453442195939.0RepeatNote=LRR 16
TgeneMACF1chr7:140494108chr1:39898207ENST0000028989329644601_462442195939.0RepeatNote=LRR 17
TgeneMACF1chr7:140494108chr1:39898207ENST0000028989329644769_479242195939.0RepeatNote=LRR 18
TgeneMACF1chr7:140494108chr1:39898207ENST0000028989329644800_490442195939.0RepeatNote=Spectrin 4
TgeneMACF1chr7:140494108chr1:39898207ENST0000028989329644909_501242195939.0RepeatNote=Spectrin 5
TgeneMACF1chr7:140494108chr1:39898207ENST0000028989329645051_507642195939.0RepeatNote=LRR 19
TgeneMACF1chr7:140494108chr1:39898207ENST0000028989329645172_519442195939.0RepeatNote=LRR 20
TgeneMACF1chr7:140494108chr1:39898207ENST0000028989329645236_534142195939.0RepeatNote=Spectrin 6
TgeneMACF1chr7:140494108chr1:39898207ENST0000028989329645281_530442195939.0RepeatNote=LRR 21
TgeneMACF1chr7:140494108chr1:39898207ENST0000028989329645348_545042195939.0RepeatNote=Spectrin 7
TgeneMACF1chr7:140494108chr1:39898207ENST0000028989329645455_555742195939.0RepeatNote=Spectrin 8
TgeneMACF1chr7:140494108chr1:39898207ENST0000028989329645695_571942195939.0RepeatNote=LRR 22
TgeneMACF1chr7:140494108chr1:39898207ENST0000028989329645783_588542195939.0RepeatNote=Spectrin 9
TgeneMACF1chr7:140494108chr1:39898207ENST0000028989329645804_582842195939.0RepeatNote=LRR 23
TgeneMACF1chr7:140494108chr1:39898207ENST0000028989329646005_611042195939.0RepeatNote=Spectrin 10
TgeneMACF1chr7:140494108chr1:39898207ENST0000028989329646115_621942195939.0RepeatNote=Spectrin 11
TgeneMACF1chr7:140494108chr1:39898207ENST0000028989329646225_632842195939.0RepeatNote=Spectrin 12
TgeneMACF1chr7:140494108chr1:39898207ENST0000028989329646333_643942195939.0RepeatNote=Spectrin 13
TgeneMACF1chr7:140494108chr1:39898207ENST0000028989329646443_654742195939.0RepeatNote=Spectrin 14
TgeneMACF1chr7:140494108chr1:39898207ENST0000028989329646496_651942195939.0RepeatNote=LRR 24
TgeneMACF1chr7:140494108chr1:39898207ENST0000028989329646552_665842195939.0RepeatNote=Spectrin 15
TgeneMACF1chr7:140494108chr1:39898207ENST0000028989329646665_676642195939.0RepeatNote=Spectrin 16
TgeneMACF1chr7:140494108chr1:39898207ENST0000028989329646771_687442195939.0RepeatNote=Spectrin 17
TgeneMACF1chr7:140494108chr1:39898207ENST0000036168959933883_395737175431.0RepeatNote=Spectrin 1
TgeneMACF1chr7:140494108chr1:39898207ENST0000036168959933936_395837175431.0RepeatNote=LRR 13
TgeneMACF1chr7:140494108chr1:39898207ENST0000036168959934000_410837175431.0RepeatNote=Spectrin 2
TgeneMACF1chr7:140494108chr1:39898207ENST0000036168959934125_415037175431.0RepeatNote=LRR 14
TgeneMACF1chr7:140494108chr1:39898207ENST0000036168959934261_428737175431.0RepeatNote=LRR 15
TgeneMACF1chr7:140494108chr1:39898207ENST0000036168959934466_457437175431.0RepeatNote=Spectrin 3
TgeneMACF1chr7:140494108chr1:39898207ENST0000036168959934511_453437175431.0RepeatNote=LRR 16
TgeneMACF1chr7:140494108chr1:39898207ENST0000036168959934601_462437175431.0RepeatNote=LRR 17
TgeneMACF1chr7:140494108chr1:39898207ENST0000036168959934769_479237175431.0RepeatNote=LRR 18
TgeneMACF1chr7:140494108chr1:39898207ENST0000036168959934800_490437175431.0RepeatNote=Spectrin 4
TgeneMACF1chr7:140494108chr1:39898207ENST0000036168959934909_501237175431.0RepeatNote=Spectrin 5
TgeneMACF1chr7:140494108chr1:39898207ENST0000036168959935051_507637175431.0RepeatNote=LRR 19
TgeneMACF1chr7:140494108chr1:39898207ENST0000036168959935172_519437175431.0RepeatNote=LRR 20
TgeneMACF1chr7:140494108chr1:39898207ENST0000036168959935236_534137175431.0RepeatNote=Spectrin 6
TgeneMACF1chr7:140494108chr1:39898207ENST0000036168959935281_530437175431.0RepeatNote=LRR 21
TgeneMACF1chr7:140494108chr1:39898207ENST0000036168959935348_545037175431.0RepeatNote=Spectrin 7
TgeneMACF1chr7:140494108chr1:39898207ENST0000036168959935455_555737175431.0RepeatNote=Spectrin 8
TgeneMACF1chr7:140494108chr1:39898207ENST0000036168959935695_571937175431.0RepeatNote=LRR 22
TgeneMACF1chr7:140494108chr1:39898207ENST0000036168959935783_588537175431.0RepeatNote=Spectrin 9
TgeneMACF1chr7:140494108chr1:39898207ENST0000036168959935804_582837175431.0RepeatNote=LRR 23
TgeneMACF1chr7:140494108chr1:39898207ENST0000036168959936005_611037175431.0RepeatNote=Spectrin 10
TgeneMACF1chr7:140494108chr1:39898207ENST0000036168959936115_621937175431.0RepeatNote=Spectrin 11
TgeneMACF1chr7:140494108chr1:39898207ENST0000036168959936225_632837175431.0RepeatNote=Spectrin 12
TgeneMACF1chr7:140494108chr1:39898207ENST0000036168959936333_643937175431.0RepeatNote=Spectrin 13
TgeneMACF1chr7:140494108chr1:39898207ENST0000036168959936443_654737175431.0RepeatNote=Spectrin 14
TgeneMACF1chr7:140494108chr1:39898207ENST0000036168959936496_651937175431.0RepeatNote=LRR 24
TgeneMACF1chr7:140494108chr1:39898207ENST0000036168959936552_665837175431.0RepeatNote=Spectrin 15
TgeneMACF1chr7:140494108chr1:39898207ENST0000036168959936665_676637175431.0RepeatNote=Spectrin 16
TgeneMACF1chr7:140494108chr1:39898207ENST0000036168959936771_687437175431.0RepeatNote=Spectrin 17
TgeneMACF1chr7:140494108chr1:39898207ENST0000037291563975695_571956757389.0RepeatNote=LRR 22
TgeneMACF1chr7:140494108chr1:39898207ENST0000037291563975783_588556757389.0RepeatNote=Spectrin 9
TgeneMACF1chr7:140494108chr1:39898207ENST0000037291563975804_582856757389.0RepeatNote=LRR 23
TgeneMACF1chr7:140494108chr1:39898207ENST0000037291563976005_611056757389.0RepeatNote=Spectrin 10
TgeneMACF1chr7:140494108chr1:39898207ENST0000037291563976115_621956757389.0RepeatNote=Spectrin 11
TgeneMACF1chr7:140494108chr1:39898207ENST0000037291563976225_632856757389.0RepeatNote=Spectrin 12
TgeneMACF1chr7:140494108chr1:39898207ENST0000037291563976333_643956757389.0RepeatNote=Spectrin 13
TgeneMACF1chr7:140494108chr1:39898207ENST0000037291563976443_654756757389.0RepeatNote=Spectrin 14
TgeneMACF1chr7:140494108chr1:39898207ENST0000037291563976496_651956757389.0RepeatNote=LRR 24
TgeneMACF1chr7:140494108chr1:39898207ENST0000037291563976552_665856757389.0RepeatNote=Spectrin 15
TgeneMACF1chr7:140494108chr1:39898207ENST0000037291563976665_676656757389.0RepeatNote=Spectrin 16
TgeneMACF1chr7:140494108chr1:39898207ENST0000037291563976771_687456757389.0RepeatNote=Spectrin 17
TgeneMACF1chr7:140494108chr1:39898207ENST0000054584460943883_395737175431.0RepeatNote=Spectrin 1
TgeneMACF1chr7:140494108chr1:39898207ENST0000054584460943936_395837175431.0RepeatNote=LRR 13
TgeneMACF1chr7:140494108chr1:39898207ENST0000054584460944000_410837175431.0RepeatNote=Spectrin 2
TgeneMACF1chr7:140494108chr1:39898207ENST0000054584460944125_415037175431.0RepeatNote=LRR 14
TgeneMACF1chr7:140494108chr1:39898207ENST0000054584460944261_428737175431.0RepeatNote=LRR 15
TgeneMACF1chr7:140494108chr1:39898207ENST0000054584460944466_457437175431.0RepeatNote=Spectrin 3
TgeneMACF1chr7:140494108chr1:39898207ENST0000054584460944511_453437175431.0RepeatNote=LRR 16
TgeneMACF1chr7:140494108chr1:39898207ENST0000054584460944601_462437175431.0RepeatNote=LRR 17
TgeneMACF1chr7:140494108chr1:39898207ENST0000054584460944769_479237175431.0RepeatNote=LRR 18
TgeneMACF1chr7:140494108chr1:39898207ENST0000054584460944800_490437175431.0RepeatNote=Spectrin 4
TgeneMACF1chr7:140494108chr1:39898207ENST0000054584460944909_501237175431.0RepeatNote=Spectrin 5
TgeneMACF1chr7:140494108chr1:39898207ENST0000054584460945051_507637175431.0RepeatNote=LRR 19
TgeneMACF1chr7:140494108chr1:39898207ENST0000054584460945172_519437175431.0RepeatNote=LRR 20
TgeneMACF1chr7:140494108chr1:39898207ENST0000054584460945236_534137175431.0RepeatNote=Spectrin 6
TgeneMACF1chr7:140494108chr1:39898207ENST0000054584460945281_530437175431.0RepeatNote=LRR 21
TgeneMACF1chr7:140494108chr1:39898207ENST0000054584460945348_545037175431.0RepeatNote=Spectrin 7
TgeneMACF1chr7:140494108chr1:39898207ENST0000054584460945455_555737175431.0RepeatNote=Spectrin 8
TgeneMACF1chr7:140494108chr1:39898207ENST0000054584460945695_571937175431.0RepeatNote=LRR 22
TgeneMACF1chr7:140494108chr1:39898207ENST0000054584460945783_588537175431.0RepeatNote=Spectrin 9
TgeneMACF1chr7:140494108chr1:39898207ENST0000054584460945804_582837175431.0RepeatNote=LRR 23
TgeneMACF1chr7:140494108chr1:39898207ENST0000054584460946005_611037175431.0RepeatNote=Spectrin 10
TgeneMACF1chr7:140494108chr1:39898207ENST0000054584460946115_621937175431.0RepeatNote=Spectrin 11
TgeneMACF1chr7:140494108chr1:39898207ENST0000054584460946225_632837175431.0RepeatNote=Spectrin 12
TgeneMACF1chr7:140494108chr1:39898207ENST0000054584460946333_643937175431.0RepeatNote=Spectrin 13
TgeneMACF1chr7:140494108chr1:39898207ENST0000054584460946443_654737175431.0RepeatNote=Spectrin 14
TgeneMACF1chr7:140494108chr1:39898207ENST0000054584460946496_651937175431.0RepeatNote=LRR 24
TgeneMACF1chr7:140494108chr1:39898207ENST0000054584460946552_665837175431.0RepeatNote=Spectrin 15
TgeneMACF1chr7:140494108chr1:39898207ENST0000054584460946665_676637175431.0RepeatNote=Spectrin 16
TgeneMACF1chr7:140494108chr1:39898207ENST0000054584460946771_687437175431.0RepeatNote=Spectrin 17

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneBRAFchr7:140494108chr1:39898207ENST00000288602-818428_432380767.0Compositional biasNote=Poly-Ser
HgeneBRAFchr7:140494108chr1:39898207ENST00000288602-818457_717380767.0DomainProtein kinase
HgeneBRAFchr7:140494108chr1:39898207ENST00000288602-818463_471380767.0Nucleotide bindingATP
TgeneMACF1chr7:140494108chr1:39898207ENST0000028989329641122_112742195939.0Compositional biasNote=Poly-Ser
TgeneMACF1chr7:140494108chr1:39898207ENST0000028989329641414_141742195939.0Compositional biasNote=Poly-Glu
TgeneMACF1chr7:140494108chr1:39898207ENST0000028989329641986_198942195939.0Compositional biasNote=Poly-Leu
TgeneMACF1chr7:140494108chr1:39898207ENST000002898932964698_70342195939.0Compositional biasNote=Poly-Glu
TgeneMACF1chr7:140494108chr1:39898207ENST0000036168959931122_112737175431.0Compositional biasNote=Poly-Ser
TgeneMACF1chr7:140494108chr1:39898207ENST0000036168959931414_141737175431.0Compositional biasNote=Poly-Glu
TgeneMACF1chr7:140494108chr1:39898207ENST0000036168959931986_198937175431.0Compositional biasNote=Poly-Leu
TgeneMACF1chr7:140494108chr1:39898207ENST000003616895993698_70337175431.0Compositional biasNote=Poly-Glu
TgeneMACF1chr7:140494108chr1:39898207ENST0000037291563971122_112756757389.0Compositional biasNote=Poly-Ser
TgeneMACF1chr7:140494108chr1:39898207ENST0000037291563971414_141756757389.0Compositional biasNote=Poly-Glu
TgeneMACF1chr7:140494108chr1:39898207ENST0000037291563971986_198956757389.0Compositional biasNote=Poly-Leu
TgeneMACF1chr7:140494108chr1:39898207ENST000003729156397698_70356757389.0Compositional biasNote=Poly-Glu
TgeneMACF1chr7:140494108chr1:39898207ENST0000054584460941122_112737175431.0Compositional biasNote=Poly-Ser
TgeneMACF1chr7:140494108chr1:39898207ENST0000054584460941414_141737175431.0Compositional biasNote=Poly-Glu
TgeneMACF1chr7:140494108chr1:39898207ENST0000054584460941986_198937175431.0Compositional biasNote=Poly-Leu
TgeneMACF1chr7:140494108chr1:39898207ENST000005458446094698_70337175431.0Compositional biasNote=Poly-Glu
TgeneMACF1chr7:140494108chr1:39898207ENST000002898932964194_29842195939.0DomainCalponin-homology (CH) 2
TgeneMACF1chr7:140494108chr1:39898207ENST00000289893296478_18142195939.0DomainCalponin-homology (CH) 1
TgeneMACF1chr7:140494108chr1:39898207ENST000002898932964868_92542195939.0DomainSH3
TgeneMACF1chr7:140494108chr1:39898207ENST000003616895993194_29837175431.0DomainCalponin-homology (CH) 2
TgeneMACF1chr7:140494108chr1:39898207ENST00000361689599378_18137175431.0DomainCalponin-homology (CH) 1
TgeneMACF1chr7:140494108chr1:39898207ENST000003616895993868_92537175431.0DomainSH3
TgeneMACF1chr7:140494108chr1:39898207ENST000003729156397194_29856757389.0DomainCalponin-homology (CH) 2
TgeneMACF1chr7:140494108chr1:39898207ENST00000372915639778_18156757389.0DomainCalponin-homology (CH) 1
TgeneMACF1chr7:140494108chr1:39898207ENST000003729156397868_92556757389.0DomainSH3
TgeneMACF1chr7:140494108chr1:39898207ENST000005458446094194_29837175431.0DomainCalponin-homology (CH) 2
TgeneMACF1chr7:140494108chr1:39898207ENST00000545844609478_18137175431.0DomainCalponin-homology (CH) 1
TgeneMACF1chr7:140494108chr1:39898207ENST000005458446094868_92537175431.0DomainSH3
TgeneMACF1chr7:140494108chr1:39898207ENST0000028989329641_29542195939.0RegionNote=Actin-binding
TgeneMACF1chr7:140494108chr1:39898207ENST0000036168959931_29537175431.0RegionNote=Actin-binding
TgeneMACF1chr7:140494108chr1:39898207ENST0000037291563971_29556757389.0RegionNote=Actin-binding
TgeneMACF1chr7:140494108chr1:39898207ENST0000054584460941_29537175431.0RegionNote=Actin-binding
TgeneMACF1chr7:140494108chr1:39898207ENST0000028989329641050_107342195939.0RepeatNote=LRR 5
TgeneMACF1chr7:140494108chr1:39898207ENST0000028989329641128_115442195939.0RepeatNote=LRR 6
TgeneMACF1chr7:140494108chr1:39898207ENST0000028989329641187_121042195939.0RepeatNote=LRR 7
TgeneMACF1chr7:140494108chr1:39898207ENST0000028989329641257_128242195939.0RepeatNote=LRR 8
TgeneMACF1chr7:140494108chr1:39898207ENST000002898932964148_17142195939.0RepeatNote=LRR 1
TgeneMACF1chr7:140494108chr1:39898207ENST0000028989329641577_162142195939.0RepeatNote=Plectin 1
TgeneMACF1chr7:140494108chr1:39898207ENST0000028989329641654_169642195939.0RepeatNote=Plectin 2
TgeneMACF1chr7:140494108chr1:39898207ENST0000028989329641769_180942195939.0RepeatNote=Plectin 3
TgeneMACF1chr7:140494108chr1:39898207ENST0000028989329641811_184842195939.0RepeatNote=Plectin 4
TgeneMACF1chr7:140494108chr1:39898207ENST0000028989329641855_188642195939.0RepeatNote=Plectin 5
TgeneMACF1chr7:140494108chr1:39898207ENST0000028989329642290_233242195939.0RepeatNote=Plectin 6
TgeneMACF1chr7:140494108chr1:39898207ENST0000028989329642367_241042195939.0RepeatNote=Plectin 7
TgeneMACF1chr7:140494108chr1:39898207ENST000002898932964240_26442195939.0RepeatNote=LRR 2
TgeneMACF1chr7:140494108chr1:39898207ENST0000028989329642411_243742195939.0RepeatNote=Plectin 8
TgeneMACF1chr7:140494108chr1:39898207ENST0000028989329642501_254342195939.0RepeatNote=Plectin 9
TgeneMACF1chr7:140494108chr1:39898207ENST0000028989329642581_261242195939.0RepeatNote=Plectin 10
TgeneMACF1chr7:140494108chr1:39898207ENST0000028989329642686_273042195939.0RepeatNote=Plectin 11
TgeneMACF1chr7:140494108chr1:39898207ENST0000028989329643239_326242195939.0RepeatNote=LRR 9
TgeneMACF1chr7:140494108chr1:39898207ENST0000028989329643264_328342195939.0RepeatNote=LRR 10
TgeneMACF1chr7:140494108chr1:39898207ENST0000028989329643646_366942195939.0RepeatNote=LRR 11
TgeneMACF1chr7:140494108chr1:39898207ENST0000028989329643696_372042195939.0RepeatNote=LRR 12
TgeneMACF1chr7:140494108chr1:39898207ENST000002898932964377_39942195939.0RepeatNote=LRR 3
TgeneMACF1chr7:140494108chr1:39898207ENST0000028989329643883_395742195939.0RepeatNote=Spectrin 1
TgeneMACF1chr7:140494108chr1:39898207ENST0000028989329643936_395842195939.0RepeatNote=LRR 13
TgeneMACF1chr7:140494108chr1:39898207ENST0000028989329644000_410842195939.0RepeatNote=Spectrin 2
TgeneMACF1chr7:140494108chr1:39898207ENST0000028989329644125_415042195939.0RepeatNote=LRR 14
TgeneMACF1chr7:140494108chr1:39898207ENST000002898932964441_46442195939.0RepeatNote=LRR 4
TgeneMACF1chr7:140494108chr1:39898207ENST0000036168959931050_107337175431.0RepeatNote=LRR 5
TgeneMACF1chr7:140494108chr1:39898207ENST0000036168959931128_115437175431.0RepeatNote=LRR 6
TgeneMACF1chr7:140494108chr1:39898207ENST0000036168959931187_121037175431.0RepeatNote=LRR 7
TgeneMACF1chr7:140494108chr1:39898207ENST0000036168959931257_128237175431.0RepeatNote=LRR 8
TgeneMACF1chr7:140494108chr1:39898207ENST000003616895993148_17137175431.0RepeatNote=LRR 1
TgeneMACF1chr7:140494108chr1:39898207ENST0000036168959931577_162137175431.0RepeatNote=Plectin 1
TgeneMACF1chr7:140494108chr1:39898207ENST0000036168959931654_169637175431.0RepeatNote=Plectin 2
TgeneMACF1chr7:140494108chr1:39898207ENST0000036168959931769_180937175431.0RepeatNote=Plectin 3
TgeneMACF1chr7:140494108chr1:39898207ENST0000036168959931811_184837175431.0RepeatNote=Plectin 4
TgeneMACF1chr7:140494108chr1:39898207ENST0000036168959931855_188637175431.0RepeatNote=Plectin 5
TgeneMACF1chr7:140494108chr1:39898207ENST0000036168959932290_233237175431.0RepeatNote=Plectin 6
TgeneMACF1chr7:140494108chr1:39898207ENST0000036168959932367_241037175431.0RepeatNote=Plectin 7
TgeneMACF1chr7:140494108chr1:39898207ENST000003616895993240_26437175431.0RepeatNote=LRR 2
TgeneMACF1chr7:140494108chr1:39898207ENST0000036168959932411_243737175431.0RepeatNote=Plectin 8
TgeneMACF1chr7:140494108chr1:39898207ENST0000036168959932501_254337175431.0RepeatNote=Plectin 9
TgeneMACF1chr7:140494108chr1:39898207ENST0000036168959932581_261237175431.0RepeatNote=Plectin 10
TgeneMACF1chr7:140494108chr1:39898207ENST0000036168959932686_273037175431.0RepeatNote=Plectin 11
TgeneMACF1chr7:140494108chr1:39898207ENST0000036168959933239_326237175431.0RepeatNote=LRR 9
TgeneMACF1chr7:140494108chr1:39898207ENST0000036168959933264_328337175431.0RepeatNote=LRR 10
TgeneMACF1chr7:140494108chr1:39898207ENST0000036168959933646_366937175431.0RepeatNote=LRR 11
TgeneMACF1chr7:140494108chr1:39898207ENST0000036168959933696_372037175431.0RepeatNote=LRR 12
TgeneMACF1chr7:140494108chr1:39898207ENST000003616895993377_39937175431.0RepeatNote=LRR 3
TgeneMACF1chr7:140494108chr1:39898207ENST000003616895993441_46437175431.0RepeatNote=LRR 4
TgeneMACF1chr7:140494108chr1:39898207ENST0000037291563971050_107356757389.0RepeatNote=LRR 5
TgeneMACF1chr7:140494108chr1:39898207ENST0000037291563971128_115456757389.0RepeatNote=LRR 6
TgeneMACF1chr7:140494108chr1:39898207ENST0000037291563971187_121056757389.0RepeatNote=LRR 7
TgeneMACF1chr7:140494108chr1:39898207ENST0000037291563971257_128256757389.0RepeatNote=LRR 8
TgeneMACF1chr7:140494108chr1:39898207ENST000003729156397148_17156757389.0RepeatNote=LRR 1
TgeneMACF1chr7:140494108chr1:39898207ENST0000037291563971577_162156757389.0RepeatNote=Plectin 1
TgeneMACF1chr7:140494108chr1:39898207ENST0000037291563971654_169656757389.0RepeatNote=Plectin 2
TgeneMACF1chr7:140494108chr1:39898207ENST0000037291563971769_180956757389.0RepeatNote=Plectin 3
TgeneMACF1chr7:140494108chr1:39898207ENST0000037291563971811_184856757389.0RepeatNote=Plectin 4
TgeneMACF1chr7:140494108chr1:39898207ENST0000037291563971855_188656757389.0RepeatNote=Plectin 5
TgeneMACF1chr7:140494108chr1:39898207ENST0000037291563972290_233256757389.0RepeatNote=Plectin 6
TgeneMACF1chr7:140494108chr1:39898207ENST0000037291563972367_241056757389.0RepeatNote=Plectin 7
TgeneMACF1chr7:140494108chr1:39898207ENST000003729156397240_26456757389.0RepeatNote=LRR 2
TgeneMACF1chr7:140494108chr1:39898207ENST0000037291563972411_243756757389.0RepeatNote=Plectin 8
TgeneMACF1chr7:140494108chr1:39898207ENST0000037291563972501_254356757389.0RepeatNote=Plectin 9
TgeneMACF1chr7:140494108chr1:39898207ENST0000037291563972581_261256757389.0RepeatNote=Plectin 10
TgeneMACF1chr7:140494108chr1:39898207ENST0000037291563972686_273056757389.0RepeatNote=Plectin 11
TgeneMACF1chr7:140494108chr1:39898207ENST0000037291563973239_326256757389.0RepeatNote=LRR 9
TgeneMACF1chr7:140494108chr1:39898207ENST0000037291563973264_328356757389.0RepeatNote=LRR 10
TgeneMACF1chr7:140494108chr1:39898207ENST0000037291563973646_366956757389.0RepeatNote=LRR 11
TgeneMACF1chr7:140494108chr1:39898207ENST0000037291563973696_372056757389.0RepeatNote=LRR 12
TgeneMACF1chr7:140494108chr1:39898207ENST000003729156397377_39956757389.0RepeatNote=LRR 3
TgeneMACF1chr7:140494108chr1:39898207ENST0000037291563973883_395756757389.0RepeatNote=Spectrin 1
TgeneMACF1chr7:140494108chr1:39898207ENST0000037291563973936_395856757389.0RepeatNote=LRR 13
TgeneMACF1chr7:140494108chr1:39898207ENST0000037291563974000_410856757389.0RepeatNote=Spectrin 2
TgeneMACF1chr7:140494108chr1:39898207ENST0000037291563974125_415056757389.0RepeatNote=LRR 14
TgeneMACF1chr7:140494108chr1:39898207ENST0000037291563974261_428756757389.0RepeatNote=LRR 15
TgeneMACF1chr7:140494108chr1:39898207ENST000003729156397441_46456757389.0RepeatNote=LRR 4
TgeneMACF1chr7:140494108chr1:39898207ENST0000037291563974466_457456757389.0RepeatNote=Spectrin 3
TgeneMACF1chr7:140494108chr1:39898207ENST0000037291563974511_453456757389.0RepeatNote=LRR 16
TgeneMACF1chr7:140494108chr1:39898207ENST0000037291563974601_462456757389.0RepeatNote=LRR 17
TgeneMACF1chr7:140494108chr1:39898207ENST0000037291563974769_479256757389.0RepeatNote=LRR 18
TgeneMACF1chr7:140494108chr1:39898207ENST0000037291563974800_490456757389.0RepeatNote=Spectrin 4
TgeneMACF1chr7:140494108chr1:39898207ENST0000037291563974909_501256757389.0RepeatNote=Spectrin 5
TgeneMACF1chr7:140494108chr1:39898207ENST0000037291563975051_507656757389.0RepeatNote=LRR 19
TgeneMACF1chr7:140494108chr1:39898207ENST0000037291563975172_519456757389.0RepeatNote=LRR 20
TgeneMACF1chr7:140494108chr1:39898207ENST0000037291563975236_534156757389.0RepeatNote=Spectrin 6
TgeneMACF1chr7:140494108chr1:39898207ENST0000037291563975281_530456757389.0RepeatNote=LRR 21
TgeneMACF1chr7:140494108chr1:39898207ENST0000037291563975348_545056757389.0RepeatNote=Spectrin 7
TgeneMACF1chr7:140494108chr1:39898207ENST0000037291563975455_555756757389.0RepeatNote=Spectrin 8
TgeneMACF1chr7:140494108chr1:39898207ENST0000054584460941050_107337175431.0RepeatNote=LRR 5
TgeneMACF1chr7:140494108chr1:39898207ENST0000054584460941128_115437175431.0RepeatNote=LRR 6
TgeneMACF1chr7:140494108chr1:39898207ENST0000054584460941187_121037175431.0RepeatNote=LRR 7
TgeneMACF1chr7:140494108chr1:39898207ENST0000054584460941257_128237175431.0RepeatNote=LRR 8
TgeneMACF1chr7:140494108chr1:39898207ENST000005458446094148_17137175431.0RepeatNote=LRR 1
TgeneMACF1chr7:140494108chr1:39898207ENST0000054584460941577_162137175431.0RepeatNote=Plectin 1
TgeneMACF1chr7:140494108chr1:39898207ENST0000054584460941654_169637175431.0RepeatNote=Plectin 2
TgeneMACF1chr7:140494108chr1:39898207ENST0000054584460941769_180937175431.0RepeatNote=Plectin 3
TgeneMACF1chr7:140494108chr1:39898207ENST0000054584460941811_184837175431.0RepeatNote=Plectin 4
TgeneMACF1chr7:140494108chr1:39898207ENST0000054584460941855_188637175431.0RepeatNote=Plectin 5
TgeneMACF1chr7:140494108chr1:39898207ENST0000054584460942290_233237175431.0RepeatNote=Plectin 6
TgeneMACF1chr7:140494108chr1:39898207ENST0000054584460942367_241037175431.0RepeatNote=Plectin 7
TgeneMACF1chr7:140494108chr1:39898207ENST000005458446094240_26437175431.0RepeatNote=LRR 2
TgeneMACF1chr7:140494108chr1:39898207ENST0000054584460942411_243737175431.0RepeatNote=Plectin 8
TgeneMACF1chr7:140494108chr1:39898207ENST0000054584460942501_254337175431.0RepeatNote=Plectin 9
TgeneMACF1chr7:140494108chr1:39898207ENST0000054584460942581_261237175431.0RepeatNote=Plectin 10
TgeneMACF1chr7:140494108chr1:39898207ENST0000054584460942686_273037175431.0RepeatNote=Plectin 11
TgeneMACF1chr7:140494108chr1:39898207ENST0000054584460943239_326237175431.0RepeatNote=LRR 9
TgeneMACF1chr7:140494108chr1:39898207ENST0000054584460943264_328337175431.0RepeatNote=LRR 10
TgeneMACF1chr7:140494108chr1:39898207ENST0000054584460943646_366937175431.0RepeatNote=LRR 11
TgeneMACF1chr7:140494108chr1:39898207ENST0000054584460943696_372037175431.0RepeatNote=LRR 12
TgeneMACF1chr7:140494108chr1:39898207ENST000005458446094377_39937175431.0RepeatNote=LRR 3
TgeneMACF1chr7:140494108chr1:39898207ENST000005458446094441_46437175431.0RepeatNote=LRR 4


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Fusion Gene Sequence for BRAF-MACF1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>10126_10126_1_BRAF-MACF1_BRAF_chr7_140494108_ENST00000288602_MACF1_chr1_39898207_ENST00000289893_length(transcript)=7554nt_BP=1201nt
CGCCTCCCTTCCCCCTCCCCGCCCGACAGCGGCCGCTCGGGCCCCGGCTCTCGGTTATAAGATGGCGGCGCTGAGCGGTGGCGGTGGTGG
CGGCGCGGAGCCGGGCCAGGCTCTGTTCAACGGGGACATGGAGCCCGAGGCCGGCGCCGGCGCCGGCGCCGCGGCCTCTTCGGCTGCGGA
CCCTGCCATTCCGGAGGAGGTGTGGAATATCAAACAAATGATTAAGTTGACACAGGAACATATAGAGGCCCTATTGGACAAATTTGGTGG
GGAGCATAATCCACCATCAATATATCTGGAGGCCTATGAAGAATACACCAGCAAGCTAGATGCACTCCAACAAAGAGAACAACAGTTATT
GGAATCTCTGGGGAACGGAACTGATTTTTCTGTTTCTAGCTCTGCATCAATGGATACCGTTACATCTTCTTCCTCTTCTAGCCTTTCAGT
GCTACCTTCATCTCTTTCAGTTTTTCAAAATCCCACAGATGTGGCACGGAGCAACCCCAAGTCACCACAAAAACCTATCGTTAGAGTCTT
CCTGCCCAACAAACAGAGGACAGTGGTACCTGCAAGGTGTGGAGTTACAGTCCGAGACAGTCTAAAGAAAGCACTGATGATGAGAGGTCT
AATCCCAGAGTGCTGTGCTGTTTACAGAATTCAGGATGGAGAGAAGAAACCAATTGGTTGGGACACTGATATTTCCTGGCTTACTGGAGA
AGAATTGCATGTGGAAGTGTTGGAGAATGTTCCACTTACAACACACAACTTTGTACGAAAAACGTTTTTCACCTTAGCATTTTGTGACTT
TTGTCGAAAGCTGCTTTTCCAGGGTTTCCGCTGTCAAACATGTGGTTATAAATTTCACCAGCGTTGTAGTACAGAAGTTCCACTGATGTG
TGTTAATTATGACCAACTTGATTTGCTGTTTGTCTCCAAGTTCTTTGAACACCACCCAATACCACAGGAAGAGGCGTCCTTAGCAGAGAC
TGCCCTAACATCTGGATCATCCCCTTCCGCACCCGCCTCGGACTCTATTGGGCCCCAAATTCTCACCAGTCCGTCTCCTTCAAAATCCAT
TCCAATTCCACAGCCCTTCCGACCAGCAGATGAAGATCATCGAAATCAATTTGGGCAACGAGACCGATCCTCATCAGCTCCCAATGTGCA
TATAAACACAATAGAACCTGTCAATATTGATTATGAGCAAGCTGCCGATGCAGAACTAGCTTGGGTTGCTGAAACAAAACGGAAACTGAT
GGCTCTGGGTCCAATTCGCCTGGAACAGGACCAGACCACAGCTCAGCTTCAGGTACAGAAGGCTTTCTCCATTGACATTATTCGACACAA
AGATTCAATGGATGAACTCTTCAGTCACCGTAGTGAAATCTTTGGCACATGTGGGGAGGAGCAAAAAACTGTATTACAGGAAAAGACAGA
GTCTCTAATACAGCAATATGAAGCCATTAGCCTACTCAATTCAGAGCGTTATGCCCGCCTAGAGCGGGCCCAGGTCTTAGTAAACCAGTT
TTGGGAAACTTATGAAGAGCTCAGCCCCTGGATTGAGGAAACTCGGGCACTAATAGCACAGTTACCCTCTCCAGCCATTGATCATGAGCA
GCTCAGGCAGCAACAAGAGGAAATGAGGCAATTAAGGGAATCTATTGCTGAACACAAACCTCATATTGACAAACTACTAAAGATAGGCCC
ACAACTAAAGGAATTAAACCCTGAGGAAGGGGAAATGGTGGAAGAAAAATACCAGAAAGCAGAAAACATGTATGCCCAAATAAAGGAGGA
GGTGCGCCAGCGAGCCCTGGCTCTGGATGAAGCCGTGTCCCAGTCCACACAGATTACAGAGTTTCATGATAAAATTGAGCCTATGTTGGA
GACACTGGAGAATCTTTCCTCTCGCCTGCGTATGCCACCACTGATCCCTGCTGAAGTAGACAAGATCAGAGAGTGCATCAGTGACAATAA
GAGTGCCACCGTGGAGCTAGAAAAACTGCAGCCATCCTTTGAGGCCTTGAAGCGCCGTGGAGAGGAGCTTATTGGACGATCTCAGGGAGC
AGACAAGGATCTGGCTGCAAAAGAAATCCAGGATAAATTGGATCAAATGGTATTCTTCTGGGAGGACATCAAAGCTCGGGCTGAAGAACG
AGAAATCAAATTTCTTGATGTCCTTGAATTAGCAGAGAAGTTCTGGTATGACATGGCAGCTCTCCTGACCACCATCAAAGACACCCAGGA
TATTGTCCATGACTTGGAAAGCCCAGGCATTGATCCTTCCATCATCAAACAACAGGTTGAAGCTGCTGAGACTATTAAGGAAGAGACAGA
TGGTCTGCATGAAGAGCTGGAGTTTATTCGGATCCTTGGAGCAGATTTGATTTTTGCCTGTGGAGAAACTGAGAAGCCTGAAGTGAGGAA
GAGCATTGATGAGATGAATAATGCTTGGGAGAACTTAAACAAAACATGGAAAGAGAGGCTAGAAAAACTTGAGGATGCTATGCAAGCTGC
TGTGCAGTATCAGGACACTCTTCAGGCTATGTTTGACTGGCTAGATAACACTGTGATTAAACTCTGCACCATGCCCCCTGTTGGCACTGA
CCTCAATACTGTTAAAGATCAGTTAAATGAAATGAAGGAGTTCAAAGTAGAAGTTTACCAACAGCAAATTGAGATGGAGAAGCTTAATCA
CCAGGGTGAACTGATGTTAAAGAAAGCTACTGATGAGACGGACAGAGACATTATACGAGAACCACTGACAGAACTCAAACACCTCTGGGA
GAACCTGGGTGAGAAAATTGCCCACCGACAGCACAAACTAGAAGGGGCTCTGTTGGCCCTTGGTCAGTTCCAGCATGCCTTAGAGGAACT
AATGAGTTGGCTGACTCATACCGAAGAGTTGTTAGATGCTCAGAGACCAATAAGTGGAGACCCAAAAGTCATTGAAGTTGAGCTCGCAAA
GCACCATGTCCTAAAAAATGATGTTTTGGCTCATCAAGCCACAGTGGAAACAGTCAACAAAGCTGGCAATGAGCTTCTTGAATCCAGTGC
TGGAGATGATGCCAGCAGCTTAAGGAGCCGTTTGGAAGCCATGAACCAATGCTGGGAGTCAGTGTTACAGAAAACAGAGGAGAGGGAGCA
GCAGCTTCAGTCAACTCTGCAGCAGGCCCAGGGCTTCCACAGTGAAATTGAAGATTTCCTCTTGGAACTTACTAGAATGGAGAGCCAGCT
TTCTGCATCTAAGCCCACAGGAGGACTTCCTGAAACTGCTAGGGAACAGCTTGATACACATATGGAACTCTATTCCCAGCTGAAAGCCAA
GGAAGAGACTTATAATCAACTACTTGACAAGGGCAGACTCATGCTTCTAAGCCGTGACGACTCTGGGTCTGGCTCCAAGACAGAACAGAG
TGTAGCACTTTTGGAGCAGAAGTGGCATGTGGTCAGCAGTAAGATGGAAGAAAGAAAGTCAAAGCTGGAAGAGGCCCTCAACTTGGCAAC
AGAATTCCAGAATTCCCTACAAGAATTTATCAACTGGCTCACTCTAGCAGAGCAGAGTTTAAACATCGCTTCTCCACCAAGCCTGATTCT
AAATACTGTCCTTTCCCAGATAGAAGAGCACAAGGTTTTTGCTAATGAAGTAAATGCTCATCGAGACCAGATCATTGAGCTGGATCAAAC
TGGGAATCAATTAAAGTTCCTTAGCCAAAAGCAGGATGTTGTTCTGATCAAGAATTTGTTGGTGAGCGTGCAGTCTCGATGGGAGAAGGT
TGTCCAGCGATCTATTGAAAGAGGGCGATCACTAGATGATGCCAGGAAGCGGGCAAAACAATTCCATGAAGCTTGGAAAAAACTGATTGA
CTGGCTAGAAGATGCAGAGAGTCACCTGGACTCAGAACTAGAGATATCCAATGACCCAGACAAAATTAAACTTCAGCTTTCTAAGCATAA
GGAGTTTCAGAAGACTCTTGGTGGCAAGCAGCCTGTGTATGATACCACAATTAGAACTGGCAGAGCACTGAAAGAAAAGACTTTGCTTCC
CGAAGATAGTCAGAAACTTGACAATTTCCTAGGAGAAGTCAGAGACAAATGGGATACTGTTTGTGGCAAGTCTGTGGAGCGGCAGCACAA
GTTGGAGGAAGCCCTGCTCTTTTCGGGTCAGTTCATGGATGCTTTGCAGGCATTGGTTGACTGGTTATACAAGGTGGAGCCACAGCTGGC
TGAGGACCAGCCCGTGCACGGGGACCTTGACCTCGTCATGAACCTCATGGATGCACACAAGGTTTTCCAGAAGGAACTGGGAAAGCGAAC
AGGAACCGTTCAGGTCCTGAAGCGGTCAGGCCGAGAGCTGATTGAGAATAGTCGAGATGACACCACTTGGGTAAAAGGACAGCTCCAGGA
ACTGAGCACTCGCTGGGACACTGTCTGTAAACTCTCTGTTTCCAAACAAAGCCGGCTTGAGCAGGCCTTAAAACAAGCGGAAGTGTTTCG
AGACACAGTCCACATGCTGTTGGAGTGGCTTTCTGAAGCAGAGCAAACGCTTCGCTTTCGGGGAGCACTTCCTGATGACACAGAGGCCCT
GCAGTCTCTCATTGACACCCATAAGGAATTCATGAAGAAAGTAGAAGAAAAGCGAGTGGACGTTAACTCAGCAGTAGCCATGGGAGAAGT
CATCCTGGCTGTCTGCCACCCCGATTGCATCACAACCATCAAACACTGGATCACCATCATCCGAGCTCGCTTCGAGGAGGTCCTGACATG
GGCTAAGCAGCACCAGCAGCGTCTTGAAACGGCCTTGTCAGAACTGGTGGCTAATGCTGAGCTCCTGGAAGAACTTCTGGCATGGATCCA
GTGGGCTGAGACCACCCTCATTCAGCGGGATCAGGAGCCAATCCCGCAGAACATTGACCGAGTTAAAGCCCTTATCGCTGAGCATCAGAC
ATTTATGGAGGAGATGACTCGCAAACAGCCTGACGTGGACCGGGTCACCAAGACATACAAAAGGAAAAACATAGAGCCTACTCACGCGCC
TTTCATAGAGAAATCCCGCAGCGGAGGCAGGAAATCCCTAAGTCAGCCAACCCCTCCTCCCATGCCAATCCTTTCACAGTCTGAAGCAAA
AAACCCACGGATCAACCAGCTTTCTGCCCGCTGGCAGCAGGTGTGGCTGTTAGCACTGGAGCGGCAAAGGAAACTGAATGATGCCTTGGA
TCGGCTGGAGGAGTTGAAAGAATTTGCCAACTTTGACTTTGATGTCTGGAGGAAAAAGTATATGCGTTGGATGAATCACAAAAAGTCTCG
AGTGATGGATTTCTTCCGGCGCATTGATAAGGACCAGGATGGGAAGATAACACGTCAGGAGTTTATCGATGGCATTTTAGCATCCAAGTT
CCCCACCACCAAGTTAGAGATGACTGCTGTGGCTGACATTTTCGACCGAGATGGGGATGGTTACATTGATTATTATGAATTTGTGGCTGC
TCTTCATCCCAACAAGGATGCGTATCGACCAACAACCGATGCAGATAAAATCGAAGATGAGGTTACAAGACAAGTGGCTCAGTGCAAATG
TGCAAAAAGGTTTCAGGTGGAGCAGATCGGAGAGAATAAATACCGGTTCTTCCTCGGCAATCAGTTTGGGGATTCTCAGCAGTTGCGGCT
GGTCCGTATTCTGCGCAGCACCGTGATGGTTCGCGTTGGTGGAGGATGGATGGCCTTGGATGAATTTTTAGTGAAAAATGATCCCTGCCG
AGCACGAGGTAGAACTAACATTGAACTTAGAGAGAAATTCATCCTACCAGAGGGAGCATCCCAGGGAATGACCCCCTTCCGCTCACGGGG
TCGAAGGTCCAAACCATCTTCCCGGGCAGCTTCCCCTACTCGTTCCAGCTCCAGTGCTAGTCAGAGTAACCACAGCTGTACATCCATGCC
ATCTTCTCCAGCCACCCCAGCCAGTGGAACCAAGGTTATCCCATCATCAGGTAGCAAGTTGAAACGACCAACACCAACTTTTCATTCTAG
TCGGACATCCCTTGCTGGTGATACCAGCAATAGTTCTTCCCCGGCCTCCACAGGTGCCAAAACTAATCGGGCAGACCCTAAAAAGTCTGC
CAGTCGCCCTGGGAGTCGGGCTGGGAGTCGAGCCGGGAGTCGAGCCAGCAGCCGGCGAGGAAGTGACGCTTCTGACTTTGACCTCTTAGA
GACGCAGTCTGCTTGTTCCGACACTTCAGAAAGCAGCGCTGCAGGGGGCCAAGGCAACTCCAGGAGAGGGCTAAACAAACCTTCCAAAAT
CCCAACCATGTCTAAGAAGACCACCACTGCCTCCCCCAGGACTCCAGGTCCCAAGCGATAACACTGTCTAAGCACCCCCAAGCCACTATC
CACTTTGAATCCTGCTCCATACATTGGGTGTATATTTATTCTGAACGGGAGAAGTTATATTGTTAAAAGTGTAAAAGAATAATTGTGTTA
TGAAGCTGCCTTATTTTTTTTCTTTTTGTAAGTTACTATTTTCATGTGAATATTTATGTAGATAAAATTTGCCTCCTGGTAACCCTGTAA
TGGATGGGGCCCAGAAATGAAATATTTGAGAAAAACAAGTGAAAAGGTCAAGATACAAATGTGTATTAAAAAAAAAAAAGCCTATTAATA
GGGTTTCTGCGCGGTGCAGGGTTGTAAACCTGCTTTATCTTTTAGGATTATTCCTAAATGCATCTTCTTTATAAACTTGACTTGCTATCT
CAGCAAGATAAATTATATTAAAAAAATAAGAATCCTGCAGTGTTTAAGGAACTCTTTTTTTGTAAATCACGGACACCTCAATTAGCAAGA
ACTGAGGGGAGGGCTTTTTCCATTGTTTAATGTTTTGTGATTTTTAGCTAAAGAGAGGGAACCTCATCTAAGTAACATTTGCACATGATA
CAGCAAAAGGAGTTCATTGCAATACTGTCTTTGGATATTGTTTCAGTACTGGGTGTTTAAAGGACAAATAGCTGCTAGAATTCAGGGGTA
AATGTAAGTGTTCAGAAAACGTCAGAACATTTGGGGTTTTAAACTGATTTGTTGCTCCCTATCCAGCCTAGACACCAGTAACTCTTGTGT
TCACCAGGACCCAGACCCTTGGCAAGGGATAGGCTCGTTGGTGACATTGTGAATTTCAGATTTGTTTTATCCACTTTTTTTGCTATTTAT
TTAAATGGTCGATCAACTTCCCACAAACTGAGGAATGAATTCCACGAGCCTGTTCTGAAAATGTGGACGTAAGACAAACACGTGCTCGTC
CTTTAATGGAGTTCACCAGCACACTTGTTAACCAGTCCTGTTTGCTTTCGTCTTTTTTTGTGCGTAATAAAGTCAACTGACCAAGTGACC
ATGAAAAGGGGCTGTCTGGGGCTCCTGTTTTTTAGCTGCTGTTCTTCAGCTCCGACCATGTTGCTGTGTGATTATCTCAATTGGTTTTAA

>10126_10126_1_BRAF-MACF1_BRAF_chr7_140494108_ENST00000288602_MACF1_chr1_39898207_ENST00000289893_length(amino acids)=2099AA_BP=380
MAALSGGGGGGAEPGQALFNGDMEPEAGAGAGAAASSAADPAIPEEVWNIKQMIKLTQEHIEALLDKFGGEHNPPSIYLEAYEEYTSKLD
ALQQREQQLLESLGNGTDFSVSSSASMDTVTSSSSSSLSVLPSSLSVFQNPTDVARSNPKSPQKPIVRVFLPNKQRTVVPARCGVTVRDS
LKKALMMRGLIPECCAVYRIQDGEKKPIGWDTDISWLTGEELHVEVLENVPLTTHNFVRKTFFTLAFCDFCRKLLFQGFRCQTCGYKFHQ
RCSTEVPLMCVNYDQLDLLFVSKFFEHHPIPQEEASLAETALTSGSSPSAPASDSIGPQILTSPSPSKSIPIPQPFRPADEDHRNQFGQR
DRSSSAPNVHINTIEPVNIDYEQAADAELAWVAETKRKLMALGPIRLEQDQTTAQLQVQKAFSIDIIRHKDSMDELFSHRSEIFGTCGEE
QKTVLQEKTESLIQQYEAISLLNSERYARLERAQVLVNQFWETYEELSPWIEETRALIAQLPSPAIDHEQLRQQQEEMRQLRESIAEHKP
HIDKLLKIGPQLKELNPEEGEMVEEKYQKAENMYAQIKEEVRQRALALDEAVSQSTQITEFHDKIEPMLETLENLSSRLRMPPLIPAEVD
KIRECISDNKSATVELEKLQPSFEALKRRGEELIGRSQGADKDLAAKEIQDKLDQMVFFWEDIKARAEEREIKFLDVLELAEKFWYDMAA
LLTTIKDTQDIVHDLESPGIDPSIIKQQVEAAETIKEETDGLHEELEFIRILGADLIFACGETEKPEVRKSIDEMNNAWENLNKTWKERL
EKLEDAMQAAVQYQDTLQAMFDWLDNTVIKLCTMPPVGTDLNTVKDQLNEMKEFKVEVYQQQIEMEKLNHQGELMLKKATDETDRDIIRE
PLTELKHLWENLGEKIAHRQHKLEGALLALGQFQHALEELMSWLTHTEELLDAQRPISGDPKVIEVELAKHHVLKNDVLAHQATVETVNK
AGNELLESSAGDDASSLRSRLEAMNQCWESVLQKTEEREQQLQSTLQQAQGFHSEIEDFLLELTRMESQLSASKPTGGLPETAREQLDTH
MELYSQLKAKEETYNQLLDKGRLMLLSRDDSGSGSKTEQSVALLEQKWHVVSSKMEERKSKLEEALNLATEFQNSLQEFINWLTLAEQSL
NIASPPSLILNTVLSQIEEHKVFANEVNAHRDQIIELDQTGNQLKFLSQKQDVVLIKNLLVSVQSRWEKVVQRSIERGRSLDDARKRAKQ
FHEAWKKLIDWLEDAESHLDSELEISNDPDKIKLQLSKHKEFQKTLGGKQPVYDTTIRTGRALKEKTLLPEDSQKLDNFLGEVRDKWDTV
CGKSVERQHKLEEALLFSGQFMDALQALVDWLYKVEPQLAEDQPVHGDLDLVMNLMDAHKVFQKELGKRTGTVQVLKRSGRELIENSRDD
TTWVKGQLQELSTRWDTVCKLSVSKQSRLEQALKQAEVFRDTVHMLLEWLSEAEQTLRFRGALPDDTEALQSLIDTHKEFMKKVEEKRVD
VNSAVAMGEVILAVCHPDCITTIKHWITIIRARFEEVLTWAKQHQQRLETALSELVANAELLEELLAWIQWAETTLIQRDQEPIPQNIDR
VKALIAEHQTFMEEMTRKQPDVDRVTKTYKRKNIEPTHAPFIEKSRSGGRKSLSQPTPPPMPILSQSEAKNPRINQLSARWQQVWLLALE
RQRKLNDALDRLEELKEFANFDFDVWRKKYMRWMNHKKSRVMDFFRRIDKDQDGKITRQEFIDGILASKFPTTKLEMTAVADIFDRDGDG
YIDYYEFVAALHPNKDAYRPTTDADKIEDEVTRQVAQCKCAKRFQVEQIGENKYRFFLGNQFGDSQQLRLVRILRSTVMVRVGGGWMALD
EFLVKNDPCRARGRTNIELREKFILPEGASQGMTPFRSRGRRSKPSSRAASPTRSSSSASQSNHSCTSMPSSPATPASGTKVIPSSGSKL
KRPTPTFHSSRTSLAGDTSNSSSPASTGAKTNRADPKKSASRPGSRAGSRAGSRASSRRGSDASDFDLLETQSACSDTSESSAAGGQGNS

--------------------------------------------------------------
>10126_10126_2_BRAF-MACF1_BRAF_chr7_140494108_ENST00000288602_MACF1_chr1_39898207_ENST00000317713_length(transcript)=7666nt_BP=1201nt
CGCCTCCCTTCCCCCTCCCCGCCCGACAGCGGCCGCTCGGGCCCCGGCTCTCGGTTATAAGATGGCGGCGCTGAGCGGTGGCGGTGGTGG
CGGCGCGGAGCCGGGCCAGGCTCTGTTCAACGGGGACATGGAGCCCGAGGCCGGCGCCGGCGCCGGCGCCGCGGCCTCTTCGGCTGCGGA
CCCTGCCATTCCGGAGGAGGTGTGGAATATCAAACAAATGATTAAGTTGACACAGGAACATATAGAGGCCCTATTGGACAAATTTGGTGG
GGAGCATAATCCACCATCAATATATCTGGAGGCCTATGAAGAATACACCAGCAAGCTAGATGCACTCCAACAAAGAGAACAACAGTTATT
GGAATCTCTGGGGAACGGAACTGATTTTTCTGTTTCTAGCTCTGCATCAATGGATACCGTTACATCTTCTTCCTCTTCTAGCCTTTCAGT
GCTACCTTCATCTCTTTCAGTTTTTCAAAATCCCACAGATGTGGCACGGAGCAACCCCAAGTCACCACAAAAACCTATCGTTAGAGTCTT
CCTGCCCAACAAACAGAGGACAGTGGTACCTGCAAGGTGTGGAGTTACAGTCCGAGACAGTCTAAAGAAAGCACTGATGATGAGAGGTCT
AATCCCAGAGTGCTGTGCTGTTTACAGAATTCAGGATGGAGAGAAGAAACCAATTGGTTGGGACACTGATATTTCCTGGCTTACTGGAGA
AGAATTGCATGTGGAAGTGTTGGAGAATGTTCCACTTACAACACACAACTTTGTACGAAAAACGTTTTTCACCTTAGCATTTTGTGACTT
TTGTCGAAAGCTGCTTTTCCAGGGTTTCCGCTGTCAAACATGTGGTTATAAATTTCACCAGCGTTGTAGTACAGAAGTTCCACTGATGTG
TGTTAATTATGACCAACTTGATTTGCTGTTTGTCTCCAAGTTCTTTGAACACCACCCAATACCACAGGAAGAGGCGTCCTTAGCAGAGAC
TGCCCTAACATCTGGATCATCCCCTTCCGCACCCGCCTCGGACTCTATTGGGCCCCAAATTCTCACCAGTCCGTCTCCTTCAAAATCCAT
TCCAATTCCACAGCCCTTCCGACCAGCAGATGAAGATCATCGAAATCAATTTGGGCAACGAGACCGATCCTCATCAGCTCCCAATGTGCA
TATAAACACAATAGAACCTGTCAATATTGATTATGAGCAAGCTGCCGATGCAGAACTAGCTTGGGTTGCTGAAACAAAACGGAAACTGAT
GGCTCTGGGTCCAATTCGCCTGGAACAGGACCAGACCACAGCTCAGCTTCAGGTACAGAAGGCTTTCTCCATTGACATTATTCGACACAA
AGATTCAATGGATGAACTCTTCAGTCACCGTAGTGAAATCTTTGGCACATGTGGGGAGGAGCAAAAAACTGTATTACAGGAAAAGACAGA
GTCTCTAATACAGCAATATGAAGCCATTAGCCTACTCAATTCAGAGCGTTATGCCCGCCTAGAGCGGGCCCAGGTCTTAGTAAACCAGTT
TTGGGAAACTTATGAAGAGCTCAGCCCCTGGATTGAGGAAACTCGGGCACTAATAGCACAGTTACCCTCTCCAGCCATTGATCATGAGCA
GCTCAGGCAGCAACAAGAGGAAATGAGGCAATTAAGGGAATCTATTGCTGAACACAAACCTCATATTGACAAACTACTAAAGATAGGCCC
ACAACTAAAGGAATTAAACCCTGAGGAAGGGGAAATGGTGGAAGAAAAATACCAGAAAGCAGAAAACATGTATGCCCAAATAAAGGAGGA
GGTGCGCCAGCGAGCCCTGGCTCTGGATGAAGCCGTGTCCCAGTCCACACAGGTATCACAGTTTCATGATAAAATTGAGCCTATGTTGGA
GACACTGGAGAATCTTTCCTCTCGCCTGCGTATGCCACCACTGATCCCTGCTGAAGTAGACAAGATCAGAGAGTGCATCAGTGACAATAA
GAGTGCCACCGTGGAGCTAGAAAAACTGCAGCCATCCTTTGAGGCCTTGAAGCGCCGTGGAGAGGAGCTTATTGGACGATCTCAGGGAGC
AGACAAGGATCTGGCTGCAAAAGAAATCCAGGATAAATTGGATCAAATGGTATTCTTCTGGGAGGACATCAAAGCTCGGGCTGAAGAACG
AGAAATCAAATTTCTTGATGTCCTTGAATTAGCAGAGAAGTTCTGGTATGACATGGCAGCTCTCCTGACCACCATCAAAGACACCCAGGA
TATTGTCCATGACTTGGAAAGCCCAGGCATTGATCCTTCCATCATCAAACAACAGGTTGAAGCTGCTGAGACTATTAAGGAAGAGACAGA
TGGTCTGCATGAAGAGCTGGAGTTTATTCGGATCCTTGGAGCAGATTTGATTTTTGCCTGTGGAGAAACTGAGAAGCCTGAAGTGAGGAA
GAGCATTGATGAGATGAATAATGCTTGGGAGAACTTAAACAAAACATGGAAAGAGAGGCTAGAAAAACTTGAGGATGCTATGCAAGCTGC
TGTGCAGTATCAGGACACTCTTCAGGCTATGTTTGACTGGCTAGATAACACTGTGATTAAACTCTGCACCATGCCCCCTGTTGGCACTGA
CCTCAATACTGTTAAAGATCAGTTAAATGAAATGAAGGAGTTCAAAGTAGAAGTTTACCAACAGCAAATTGAGATGGAGAAGCTTAATCA
CCAGGGTGAACTGATGTTAAAGAAAGCTACTGATGAGACGGACAGAGACATTATACGAGAACCACTGACAGAACTCAAACACCTCTGGGA
GAACCTGGGTGAGAAAATTGCCCACCGACAGCACAAACTAGAAGGGGCTCTGTTGGCCCTTGGTCAGTTCCAGCATGCCTTAGAGGAACT
AATGAGTTGGCTGACTCATACCGAAGAGTTGTTAGATGCTCAGAGACCAATAAGTGGAGACCCAAAAGTCATTGAAGTTGAGCTCGCAAA
GCACCATGTCCTAAAAAATGATGTTTTGGCTCATCAAGCCACAGTGGAAACAGTCAACAAAGCTGGCAATGAGCTTCTTGAATCCAGTGC
TGGAGATGATGCCAGCAGCTTAAGGAGCCGTTTGGAAGCCATGAACCAATGCTGGGAGTCAGTGTTACAGAAAACAGAGGAGAGGGAGCA
GCAGCTTCAGTCAACTCTGCAGCAGGCCCAGGGCTTCCACAGTGAAATTGAAGATTTCCTCTTGGAACTTACTAGAATGGAGAGCCAGCT
TTCTGCATCTAAGCCCACAGGAGGACTTCCTGAAACTGCTAGGGAACAGCTTGATACACATATGGAACTCTATTCCCAGCTGAAAGCCAA
GGAAGAGACTTATAATCAACTACTTGACAAGGGCAGACTCATGCTTCTAAGCCGTGACGACTCTGGGTCTGGCTCCAAGACAGAACAGAG
TGTAGCACTTTTGGAGCAGAAGTGGCATGTGGTCAGCAGTAAGATGGAAGAAAGAAAGTCAAAGCTGGAAGAGGCCCTCAACTTGGCAAC
AGAATTCCAGAATTCCCTACAAGAATTTATCAACTGGCTCACTCTAGCAGAGCAGAGTTTAAACATCGCTTCTCCACCAAGCCTGATTCT
AAATACTGTCCTTTCCCAGATAGAAGAGCACAAGGTTTTTGCTAATGAAGTAAATGCTCATCGAGACCAGATCATTGAGCTGGATCAAAC
TGGGAATCAATTAAAGTTCCTTAGCCAAAAGCAGGATGTTGTTCTGATCAAGAATTTGTTGGTGAGCGTGCAGTCTCGATGGGAGAAGGT
TGTCCAGCGATCTATTGAAAGAGGGCGATCACTAGATGATGCCAGGAAGCGGGCAAAACAATTCCATGAAGCTTGGAAAAAACTGATTGA
CTGGCTAGAAGATGCAGAGAGTCACCTGGACTCAGAACTAGAGATATCCAATGACCCAGACAAAATTAAACTTCAGCTTTCTAAGCATAA
GGAGTTTCAGAAGACTCTTGGTGGCAAGCAGCCTGTGTATGATACCACAATTAGAACTGGCAGAGCACTGAAAGAAAAGACTTTGCTTCC
CGAAGATAGTCAGAAACTTGACAATTTCCTAGGAGAAGTCAGAGACAAATGGGATACTGTTTGTGGCAAGTCTGTGGAGCGGCAGCACAA
GTTGGAGGAAGCCCTGCTCTTTTCGGGTCAGTTCATGGATGCTTTGCAGGCATTGGTTGACTGGTTATACAAGGTGGAGCCACAGCTGGC
TGAGGACCAGCCCGTGCACGGGGACCTTGACCTCGTCATGAACCTCATGGATGCACACAAGGTTTTCCAGAAGGAACTGGGAAAGCGAAC
AGGAACCGTTCAGGTCCTGAAGCGGTCAGGCCGAGAGCTGATTGAGAATAGTCGAGATGACACCACTTGGGTAAAAGGACAGCTCCAGGA
ACTGAGCACTCGCTGGGACACTGTCTGTAAACTCTCTGTTTCCAAACAAAGCCGGCTTGAGCAGGCCTTAAAACAAGCGGAAGTGTTTCG
AGACACAGTCCACATGCTGTTGGAGTGGCTTTCTGAAGCAGAGCAAACGCTTCGCTTTCGGGGAGCACTTCCTGATGACACAGAGGCCCT
GCAGTCTCTCATTGACACCCATAAGGAATTCATGAAGAAAGTAGAAGAAAAGCGAGTGGACGTTAACTCAGCAGTAGCCATGGGAGAAGT
CATCCTGGCTGTCTGCCACCCCGATTGCATCACAACCATCAAACACTGGATCACCATCATCCGAGCTCGCTTCGAGGAGGTCCTGACATG
GGCTAAGCAGCACCAGCAGCGTCTTGAAACGGCCTTGTCAGAACTGGTGGCTAATGCTGAGCTCCTGGAAGAACTTCTGGCATGGATCCA
GTGGGCTGAGACCACCCTCATTCAGCGGGATCAGGAGCCAATCCCGCAGAACATTGACCGAGTTAAAGCCCTTATCGCTGAGCATCAGAC
ATTTATGGAGGAGATGACTCGCAAACAGCCTGACGTGGACCGGGTCACCAAGACATACAAAAGGAAAAACATAGAGCCTACTCACGCGCC
TTTCATAGAGAAATCCCGCAGCGGAGGCAGGAAATCCCTAAGTCAGCCAACCCCTCCTCCCATGCCAATCCTTTCACAGTCTGAAGCAAA
AAACCCACGGATCAACCAGCTTTCTGCCCGCTGGCAGCAGGTGTGGCTGTTAGCACTGGAGCGGCAAAGGAAACTGAATGATGCCTTGGA
TCGGCTGGAGGAGTTGAAAGAATTTGCCAACTTTGACTTTGATGTCTGGAGGAAAAAGTATATGCGTTGGATGAATCACAAAAAGTCTCG
AGTGATGGATTTCTTCCGGCGCATTGATAAGGACCAGGATGGGAAGATAACACGTCAGGAGTTTATCGATGGCATTTTAGCATCCAAGTT
CCCCACCACCAAGTTAGAGATGACTGCTGTGGCTGACATTTTCGACCGAGATGGGGATGGTTACATTGATTATTATGAATTTGTGGCTGC
TCTTCATCCCAACAAGGATGCGTATCGACCAACAACCGATGCAGATAAAATCGAAGATGAGGTTACAAGACAAGTGGCTCAGTGCAAATG
TGCAAAAAGGTTTCAGGTGGAGCAGATCGGAGAGAATAAATACCGGTTTGGGGATTCTCAGCAGTTGCGGCTGGTCCGTATTCTGCGCAG
CACCGTGATGGTTCGCGTTGGTGGAGGATGGATGGCCTTGGATGAATTTTTAGTGAAAAATGATCCCTGCCGAGCACGAGGTAGAACTAA
CATTGAACTTAGAGAGAAATTCATCCTACCAGAGGGAGCATCCCAGGGAATGACCCCCTTCCGCTCACGGGGTCGAAGGTCCAAACCATC
TTCCCGGGCAGCTTCCCCTACTCGTTCCAGCTCCAGTGCTAGTCAGAGTAACCACAGCTGTACATCCATGCCATCTTCTCCAGCCACCCC
AGCCAGTGGAACCAAGGTTATCCCATCATCAGGTAGCAAGTTGAAACGACCAACACCAACTTTTCATTCTAGTCGGACATCCCTTGCTGG
TGATACCAGCAATAGTTCTTCCCCGGCCTCCACAGGTGCCAAAACTAATCGGGCAGACCCTAAAAAGTCTGCCAGTCGCCCTGGGAGTCG
GGCTGGGAGTCGAGCCGGGAGTCGAGCCAGCAGCCGGCGAGGAAGTGACGCTTCTGACTTTGACCTCTTAGAGACGCAGTCTGCTTGTTC
CGACACTTCAGAAAGCAGCGCTGCAGGGGGCCAAGGCAACTCCAGGAGAGGGCTAAACAAACCTTCCAAAATCCCAACCATGTCTAAGAA
GACCACCACTGCCTCCCCCAGGACTCCAGGTCCCAAGCGATAACACTGTCTAAGCACCCCCAAGCCACTATCCACTTTGAATCCTGCTCC
ATACATTGGGTGTATATTTATTCTGAACGGGAGAAGTTATATTGTTAAAAGTGTAAAAGAATAATTGTGTTATGAAGCTGCCTTATTTTT
TTTCTTTTTGTAAGTTACTATTTTCATGTGAATATTTATGTAGATAAAATTTGCCTCCTGGTAACCCTGTAATGGATGGGGCCCAGAAAT
GAAATATTTGAGAAAAACAAGTGAAAAGGTCAAGATACAAATGTGTATTAAAAAAAAAAAAGCCTATTAATAGGGTTTCTGCGCGGTGCA
GGGTTGTAAACCTGCTTTATCTTTTAGGATTATTCCTAAATGCATCTTCTTTATAAACTTGACTTGCTATCTCAGCAAGATAAATTATAT
TAAAAAAATAAGAATCCTGCAGTGTTTAAGGAACTCTTTTTTTGTAAATCACGGACACCTCAATTAGCAAGAACTGAGGGGAGGGCTTTT
TCCATTGTTTAATGTTTTGTGATTTTTAGCTAAAGAGAGGGAACCTCATCTAAGTAACATTTGCACATGATACAGCAAAAGGAGTTCATT
GCAATACTGTCTTTGGATATTGTTTCAGTACTGGGTGTTTAAAGGACAAATAGCTGCTAGAATTCAGGGGTAAATGTAAGTGTTCAGAAA
ACGTCAGAACATTTGGGGTTTTAAACTGATTTGTTGCTCCCTATCCAGCCTAGACACCAGTAACTCTTGTGTTCACCAGGACCCAGACCC
TTGGCAAGGGATAGGCTCGTTGGTGACATTGTGAATTTCAGATTTGTTTTATCCACTTTTTTTGCTATTTATTTAAATGGTCGATCAACT
TCCCACAAACTGAGGAATGAATTCCACGAGCCTGTTCTGAAAATGTGGACGTAAGACAAACACGTGCTCGTCCTTTAATGGAGTTCACCA
GCACACTTGTTAACCAGTCCTGTTTGCTTTCGTCTTTTTTTGTGCGTAATAAAGTCAACTGACCAAGTGACCATGAAAAGGGGCTGTCTG
GGGCTCCTGTTTTTTAGCTGCTGTTCTTCAGCTCCGACCATGTTGCTGTGTGATTATCTCAATTGGTTTTAATTGAGGCAGAAACTGAAG
CTCTACCAATGAACTGTTTAGAAACAAGACACACTTTTGTATTAAAATTGCTTGCAGTAACAAATATTTTGTATTTCCTGATTTTCTTTT
CAACTATTACCTTATCTATAAATGTTACCCTGGGGTATAATCATGTTGTAGGTACTTAAATGCATTCCGCAAATCAAAATATCTTGATGG

>10126_10126_2_BRAF-MACF1_BRAF_chr7_140494108_ENST00000288602_MACF1_chr1_39898207_ENST00000317713_length(amino acids)=2093AA_BP=380
MAALSGGGGGGAEPGQALFNGDMEPEAGAGAGAAASSAADPAIPEEVWNIKQMIKLTQEHIEALLDKFGGEHNPPSIYLEAYEEYTSKLD
ALQQREQQLLESLGNGTDFSVSSSASMDTVTSSSSSSLSVLPSSLSVFQNPTDVARSNPKSPQKPIVRVFLPNKQRTVVPARCGVTVRDS
LKKALMMRGLIPECCAVYRIQDGEKKPIGWDTDISWLTGEELHVEVLENVPLTTHNFVRKTFFTLAFCDFCRKLLFQGFRCQTCGYKFHQ
RCSTEVPLMCVNYDQLDLLFVSKFFEHHPIPQEEASLAETALTSGSSPSAPASDSIGPQILTSPSPSKSIPIPQPFRPADEDHRNQFGQR
DRSSSAPNVHINTIEPVNIDYEQAADAELAWVAETKRKLMALGPIRLEQDQTTAQLQVQKAFSIDIIRHKDSMDELFSHRSEIFGTCGEE
QKTVLQEKTESLIQQYEAISLLNSERYARLERAQVLVNQFWETYEELSPWIEETRALIAQLPSPAIDHEQLRQQQEEMRQLRESIAEHKP
HIDKLLKIGPQLKELNPEEGEMVEEKYQKAENMYAQIKEEVRQRALALDEAVSQSTQVSQFHDKIEPMLETLENLSSRLRMPPLIPAEVD
KIRECISDNKSATVELEKLQPSFEALKRRGEELIGRSQGADKDLAAKEIQDKLDQMVFFWEDIKARAEEREIKFLDVLELAEKFWYDMAA
LLTTIKDTQDIVHDLESPGIDPSIIKQQVEAAETIKEETDGLHEELEFIRILGADLIFACGETEKPEVRKSIDEMNNAWENLNKTWKERL
EKLEDAMQAAVQYQDTLQAMFDWLDNTVIKLCTMPPVGTDLNTVKDQLNEMKEFKVEVYQQQIEMEKLNHQGELMLKKATDETDRDIIRE
PLTELKHLWENLGEKIAHRQHKLEGALLALGQFQHALEELMSWLTHTEELLDAQRPISGDPKVIEVELAKHHVLKNDVLAHQATVETVNK
AGNELLESSAGDDASSLRSRLEAMNQCWESVLQKTEEREQQLQSTLQQAQGFHSEIEDFLLELTRMESQLSASKPTGGLPETAREQLDTH
MELYSQLKAKEETYNQLLDKGRLMLLSRDDSGSGSKTEQSVALLEQKWHVVSSKMEERKSKLEEALNLATEFQNSLQEFINWLTLAEQSL
NIASPPSLILNTVLSQIEEHKVFANEVNAHRDQIIELDQTGNQLKFLSQKQDVVLIKNLLVSVQSRWEKVVQRSIERGRSLDDARKRAKQ
FHEAWKKLIDWLEDAESHLDSELEISNDPDKIKLQLSKHKEFQKTLGGKQPVYDTTIRTGRALKEKTLLPEDSQKLDNFLGEVRDKWDTV
CGKSVERQHKLEEALLFSGQFMDALQALVDWLYKVEPQLAEDQPVHGDLDLVMNLMDAHKVFQKELGKRTGTVQVLKRSGRELIENSRDD
TTWVKGQLQELSTRWDTVCKLSVSKQSRLEQALKQAEVFRDTVHMLLEWLSEAEQTLRFRGALPDDTEALQSLIDTHKEFMKKVEEKRVD
VNSAVAMGEVILAVCHPDCITTIKHWITIIRARFEEVLTWAKQHQQRLETALSELVANAELLEELLAWIQWAETTLIQRDQEPIPQNIDR
VKALIAEHQTFMEEMTRKQPDVDRVTKTYKRKNIEPTHAPFIEKSRSGGRKSLSQPTPPPMPILSQSEAKNPRINQLSARWQQVWLLALE
RQRKLNDALDRLEELKEFANFDFDVWRKKYMRWMNHKKSRVMDFFRRIDKDQDGKITRQEFIDGILASKFPTTKLEMTAVADIFDRDGDG
YIDYYEFVAALHPNKDAYRPTTDADKIEDEVTRQVAQCKCAKRFQVEQIGENKYRFGDSQQLRLVRILRSTVMVRVGGGWMALDEFLVKN
DPCRARGRTNIELREKFILPEGASQGMTPFRSRGRRSKPSSRAASPTRSSSSASQSNHSCTSMPSSPATPASGTKVIPSSGSKLKRPTPT
FHSSRTSLAGDTSNSSSPASTGAKTNRADPKKSASRPGSRAGSRAGSRASSRRGSDASDFDLLETQSACSDTSESSAAGGQGNSRRGLNK

--------------------------------------------------------------
>10126_10126_3_BRAF-MACF1_BRAF_chr7_140494108_ENST00000288602_MACF1_chr1_39898207_ENST00000361689_length(transcript)=7536nt_BP=1201nt
CGCCTCCCTTCCCCCTCCCCGCCCGACAGCGGCCGCTCGGGCCCCGGCTCTCGGTTATAAGATGGCGGCGCTGAGCGGTGGCGGTGGTGG
CGGCGCGGAGCCGGGCCAGGCTCTGTTCAACGGGGACATGGAGCCCGAGGCCGGCGCCGGCGCCGGCGCCGCGGCCTCTTCGGCTGCGGA
CCCTGCCATTCCGGAGGAGGTGTGGAATATCAAACAAATGATTAAGTTGACACAGGAACATATAGAGGCCCTATTGGACAAATTTGGTGG
GGAGCATAATCCACCATCAATATATCTGGAGGCCTATGAAGAATACACCAGCAAGCTAGATGCACTCCAACAAAGAGAACAACAGTTATT
GGAATCTCTGGGGAACGGAACTGATTTTTCTGTTTCTAGCTCTGCATCAATGGATACCGTTACATCTTCTTCCTCTTCTAGCCTTTCAGT
GCTACCTTCATCTCTTTCAGTTTTTCAAAATCCCACAGATGTGGCACGGAGCAACCCCAAGTCACCACAAAAACCTATCGTTAGAGTCTT
CCTGCCCAACAAACAGAGGACAGTGGTACCTGCAAGGTGTGGAGTTACAGTCCGAGACAGTCTAAAGAAAGCACTGATGATGAGAGGTCT
AATCCCAGAGTGCTGTGCTGTTTACAGAATTCAGGATGGAGAGAAGAAACCAATTGGTTGGGACACTGATATTTCCTGGCTTACTGGAGA
AGAATTGCATGTGGAAGTGTTGGAGAATGTTCCACTTACAACACACAACTTTGTACGAAAAACGTTTTTCACCTTAGCATTTTGTGACTT
TTGTCGAAAGCTGCTTTTCCAGGGTTTCCGCTGTCAAACATGTGGTTATAAATTTCACCAGCGTTGTAGTACAGAAGTTCCACTGATGTG
TGTTAATTATGACCAACTTGATTTGCTGTTTGTCTCCAAGTTCTTTGAACACCACCCAATACCACAGGAAGAGGCGTCCTTAGCAGAGAC
TGCCCTAACATCTGGATCATCCCCTTCCGCACCCGCCTCGGACTCTATTGGGCCCCAAATTCTCACCAGTCCGTCTCCTTCAAAATCCAT
TCCAATTCCACAGCCCTTCCGACCAGCAGATGAAGATCATCGAAATCAATTTGGGCAACGAGACCGATCCTCATCAGCTCCCAATGTGCA
TATAAACACAATAGAACCTGTCAATATTGATTATGAGCAAGCTGCCGATGCAGAACTAGCTTGGGTTGCTGAAACAAAACGGAAACTGAT
GGCTCTGGGTCCAATTCGCCTGGAACAGGACCAGACCACAGCTCAGCTTCAGGTACAGAAGGCTTTCTCCATTGACATTATTCGACACAA
AGATTCAATGGATGAACTCTTCAGTCACCGTAGTGAAATCTTTGGCACATGTGGGGAGGAGCAAAAAACTGTATTACAGGAAAAGACAGA
GTCTCTAATACAGCAATATGAAGCCATTAGCCTACTCAATTCAGAGCGTTATGCCCGCCTAGAGCGGGCCCAGGTCTTAGTAAACCAGTT
TTGGGAAACTTATGAAGAGCTCAGCCCCTGGATTGAGGAAACTCGGGCACTAATAGCACAGTTACCCTCTCCAGCCATTGATCATGAGCA
GCTCAGGCAGCAACAAGAGGAAATGAGGCAATTAAGGGAATCTATTGCTGAACACAAACCTCATATTGACAAACTACTAAAGATAGGCCC
ACAACTAAAGGAATTAAACCCTGAGGAAGGGGAAATGGTGGAAGAAAAATACCAGAAAGCAGAAAACATGTATGCCCAAATAAAGGAGGA
GGTGCGCCAGCGAGCCCTGGCTCTGGATGAAGCCGTGTCCCAGTCCACACAGATTACAGAGTTTCATGATAAAATTGAGCCTATGTTGGA
GACACTGGAGAATCTTTCCTCTCGCCTGCGTATGCCACCACTGATCCCTGCTGAAGTAGACAAGATCAGAGAGTGCATCAGTGACAATAA
GAGTGCCACCGTGGAGCTAGAAAAACTGCAGCCATCCTTTGAGGCCTTGAAGCGCCGTGGAGAGGAGCTTATTGGACGATCTCAGGGAGC
AGACAAGGATCTGGCTGCAAAAGAAATCCAGGATAAATTGGATCAAATGGTATTCTTCTGGGAGGACATCAAAGCTCGGGCTGAAGAACG
AGAAATCAAATTTCTTGATGTCCTTGAATTAGCAGAGAAGTTCTGGTATGACATGGCAGCTCTCCTGACCACCATCAAAGACACCCAGGA
TATTGTCCATGACTTGGAAAGCCCAGGCATTGATCCTTCCATCATCAAACAACAGGTTGAAGCTGCTGAGACTATTAAGGAAGAGACAGA
TGGTCTGCATGAAGAGCTGGAGTTTATTCGGATCCTTGGAGCAGATTTGATTTTTGCCTGTGGAGAAACTGAGAAGCCTGAAGTGAGGAA
GAGCATTGATGAGATGAATAATGCTTGGGAGAACTTAAACAAAACATGGAAAGAGAGGCTAGAAAAACTTGAGGATGCTATGCAAGCTGC
TGTGCAGTATCAGGACACTCTTCAGGCTATGTTTGACTGGCTAGATAACACTGTGATTAAACTCTGCACCATGCCCCCTGTTGGCACTGA
CCTCAATACTGTTAAAGATCAGTTAAATGAAATGAAGGAGTTCAAAGTAGAAGTTTACCAACAGCAAATTGAGATGGAGAAGCTTAATCA
CCAGGGTGAACTGATGTTAAAGAAAGCTACTGATGAGACGGACAGAGACATTATACGAGAACCACTGACAGAACTCAAACACCTCTGGGA
GAACCTGGGTGAGAAAATTGCCCACCGACAGCACAAACTAGAAGGGGCTCTGTTGGCCCTTGGTCAGTTCCAGCATGCCTTAGAGGAACT
AATGAGTTGGCTGACTCATACCGAAGAGTTGTTAGATGCTCAGAGACCAATAAGTGGAGACCCAAAAGTCATTGAAGTTGAGCTCGCAAA
GCACCATGTCCTAAAAAATGATGTTTTGGCTCATCAAGCCACAGTGGAAACAGTCAACAAAGCTGGCAATGAGCTTCTTGAATCCAGTGC
TGGAGATGATGCCAGCAGCTTAAGGAGCCGTTTGGAAGCCATGAACCAATGCTGGGAGTCAGTGTTACAGAAAACAGAGGAGAGGGAGCA
GCAGCTTCAGTCAACTCTGCAGCAGGCCCAGGGCTTCCACAGTGAAATTGAAGATTTCCTCTTGGAACTTACTAGAATGGAGAGCCAGCT
TTCTGCATCTAAGCCCACAGGAGGACTTCCTGAAACTGCTAGGGAACAGCTTGATACACATATGGAACTCTATTCCCAGCTGAAAGCCAA
GGAAGAGACTTATAATCAACTACTTGACAAGGGCAGACTCATGCTTCTAAGCCGTGACGACTCTGGGTCTGGCTCCAAGACAGAACAGAG
TGTAGCACTTTTGGAGCAGAAGTGGCATGTGGTCAGCAGTAAGATGGAAGAAAGAAAGTCAAAGCTGGAAGAGGCCCTCAACTTGGCAAC
AGAATTCCAGAATTCCCTACAAGAATTTATCAACTGGCTCACTCTAGCAGAGCAGAGTTTAAACATCGCTTCTCCACCAAGCCTGATTCT
AAATACTGTCCTTTCCCAGATAGAAGAGCACAAGGTTTTTGCTAATGAAGTAAATGCTCATCGAGACCAGATCATTGAGCTGGATCAAAC
TGGGAATCAATTAAAGTTCCTTAGCCAAAAGCAGGATGTTGTTCTGATCAAGAATTTGTTGGTGAGCGTGCAGTCTCGATGGGAGAAGGT
TGTCCAGCGATCTATTGAAAGAGGGCGATCACTAGATGATGCCAGGAAGCGGGCAAAACAATTCCATGAAGCTTGGAAAAAACTGATTGA
CTGGCTAGAAGATGCAGAGAGTCACCTGGACTCAGAACTAGAGATATCCAATGACCCAGACAAAATTAAACTTCAGCTTTCTAAGCATAA
GGAGTTTCAGAAGACTCTTGGTGGCAAGCAGCCTGTGTATGATACCACAATTAGAACTGGCAGAGCACTGAAAGAAAAGACTTTGCTTCC
CGAAGATAGTCAGAAACTTGACAATTTCCTAGGAGAAGTCAGAGACAAATGGGATACTGTTTGTGGCAAGTCTGTGGAGCGGCAGCACAA
GTTGGAGGAAGCCCTGCTCTTTTCGGGTCAGTTCATGGATGCTTTGCAGGCATTGGTTGACTGGTTATACAAGGTGGAGCCACAGCTGGC
TGAGGACCAGCCCGTGCACGGGGACCTTGACCTCGTCATGAACCTCATGGATGCACACAAGGTTTTCCAGAAGGAACTGGGAAAGCGAAC
AGGAACCGTTCAGGTCCTGAAGCGGTCAGGCCGAGAGCTGATTGAGAATAGTCGAGATGACACCACTTGGGTAAAAGGACAGCTCCAGGA
ACTGAGCACTCGCTGGGACACTGTCTGTAAACTCTCTGTTTCCAAACAAAGCCGGCTTGAGCAGGCCTTAAAACAAGCGGAAGTGTTTCG
AGACACAGTCCACATGCTGTTGGAGTGGCTTTCTGAAGCAGAGCAAACGCTTCGCTTTCGGGGAGCACTTCCTGATGACACAGAGGCCCT
GCAGTCTCTCATTGACACCCATAAGGAATTCATGAAGAAAGTAGAAGAAAAGCGAGTGGACGTTAACTCAGCAGTAGCCATGGGAGAAGT
CATCCTGGCTGTCTGCCACCCCGATTGCATCACAACCATCAAACACTGGATCACCATCATCCGAGCTCGCTTCGAGGAGGTCCTGACATG
GGCTAAGCAGCACCAGCAGCGTCTTGAAACGGCCTTGTCAGAACTGGTGGCTAATGCTGAGCTCCTGGAAGAACTTCTGGCATGGATCCA
GTGGGCTGAGACCACCCTCATTCAGCGGGATCAGGAGCCAATCCCGCAGAACATTGACCGAGTTAAAGCCCTTATCGCTGAGCATCAGAC
ATTTATGGAGGAGATGACTCGCAAACAGCCTGACGTGGACCGGGTCACCAAGACATACAAAAGGAAAAACATAGAGCCTACTCACGCGCC
TTTCATAGAGAAATCCCGCAGCGGAGGCAGGAAATCCCTAAGTCAGCCAACCCCTCCTCCCATGCCAATCCTTTCACAGTCTGAAGCAAA
AAACCCACGGATCAACCAGCTTTCTGCCCGCTGGCAGCAGGTGTGGCTGTTAGCACTGGAGCGGCAAAGGAAACTGAATGATGCCTTGGA
TCGGCTGGAGGAGTTGAAAGAATTTGCCAACTTTGACTTTGATGTCTGGAGGAAAAAGTATATGCGTTGGATGAATCACAAAAAGTCTCG
AGTGATGGATTTCTTCCGGCGCATTGATAAGGACCAGGATGGGAAGATAACACGTCAGGAGTTTATCGATGGCATTTTAGCATCCAAGTT
CCCCACCACCAAGTTAGAGATGACTGCTGTGGCTGACATTTTCGACCGAGATGGGGATGGTTACATTGATTATTATGAATTTGTGGCTGC
TCTTCATCCCAACAAGGATGCGTATCGACCAACAACCGATGCAGATAAAATCGAAGATGAGGTTACAAGACAAGTGGCTCAGTGCAAATG
TGCAAAAAGGTTTCAGGTGGAGCAGATCGGAGAGAATAAATACCGGTTTGGGGATTCTCAGCAGTTGCGGCTGGTCCGTATTCTGCGCAG
CACCGTGATGGTTCGCGTTGGTGGAGGATGGATGGCCTTGGATGAATTTTTAGTGAAAAATGATCCCTGCCGAGCACGAGGTAGAACTAA
CATTGAACTTAGAGAGAAATTCATCCTACCAGAGGGAGCATCCCAGGGAATGACCCCCTTCCGCTCACGGGGTCGAAGGTCCAAACCATC
TTCCCGGGCAGCTTCCCCTACTCGTTCCAGCTCCAGTGCTAGTCAGAGTAACCACAGCTGTACATCCATGCCATCTTCTCCAGCCACCCC
AGCCAGTGGAACCAAGGTTATCCCATCATCAGGTAGCAAGTTGAAACGACCAACACCAACTTTTCATTCTAGTCGGACATCCCTTGCTGG
TGATACCAGCAATAGTTCTTCCCCGGCCTCCACAGGTGCCAAAACTAATCGGGCAGACCCTAAAAAGTCTGCCAGTCGCCCTGGGAGTCG
GGCTGGGAGTCGAGCCGGGAGTCGAGCCAGCAGCCGGCGAGGAAGTGACGCTTCTGACTTTGACCTCTTAGAGACGCAGTCTGCTTGTTC
CGACACTTCAGAAAGCAGCGCTGCAGGGGGCCAAGGCAACTCCAGGAGAGGGCTAAACAAACCTTCCAAAATCCCAACCATGTCTAAGAA
GACCACCACTGCCTCCCCCAGGACTCCAGGTCCCAAGCGATAACACTGTCTAAGCACCCCCAAGCCACTATCCACTTTGAATCCTGCTCC
ATACATTGGGTGTATATTTATTCTGAACGGGAGAAGTTATATTGTTAAAAGTGTAAAAGAATAATTGTGTTATGAAGCTGCCTTATTTTT
TTTCTTTTTGTAAGTTACTATTTTCATGTGAATATTTATGTAGATAAAATTTGCCTCCTGGTAACCCTGTAATGGATGGGGCCCAGAAAT
GAAATATTTGAGAAAAACAAGTGAAAAGGTCAAGATACAAATGTGTATTAAAAAAAAAAAAGCCTATTAATAGGGTTTCTGCGCGGTGCA
GGGTTGTAAACCTGCTTTATCTTTTAGGATTATTCCTAAATGCATCTTCTTTATAAACTTGACTTGCTATCTCAGCAAGATAAATTATAT
TAAAAAAATAAGAATCCTGCAGTGTTTAAGGAACTCTTTTTTTGTAAATCACGGACACCTCAATTAGCAAGAACTGAGGGGAGGGCTTTT
TCCATTGTTTAATGTTTTGTGATTTTTAGCTAAAGAGAGGGAACCTCATCTAAGTAACATTTGCACATGATACAGCAAAAGGAGTTCATT
GCAATACTGTCTTTGGATATTGTTTCAGTACTGGGTGTTTAAAGGACAAATAGCTGCTAGAATTCAGGGGTAAATGTAAGTGTTCAGAAA
ACGTCAGAACATTTGGGGTTTTAAACTGATTTGTTGCTCCCTATCCAGCCTAGACACCAGTAACTCTTGTGTTCACCAGGACCCAGACCC
TTGGCAAGGGATAGGCTCGTTGGTGACATTGTGAATTTCAGATTTGTTTTATCCACTTTTTTTGCTATTTATTTAAATGGTCGATCAACT
TCCCACAAACTGAGGAATGAATTCCACGAGCCTGTTCTGAAAATGTGGACGTAAGACAAACACGTGCTCGTCCTTTAATGGAGTTCACCA
GCACACTTGTTAACCAGTCCTGTTTGCTTTCGTCTTTTTTTGTGCGTAATAAAGTCAACTGACCAAGTGACCATGAAAAGGGGCTGTCTG
GGGCTCCTGTTTTTTAGCTGCTGTTCTTCAGCTCCGACCATGTTGCTGTGTGATTATCTCAATTGGTTTTAATTGAGGCAGAAACTGAAG

>10126_10126_3_BRAF-MACF1_BRAF_chr7_140494108_ENST00000288602_MACF1_chr1_39898207_ENST00000361689_length(amino acids)=2093AA_BP=380
MAALSGGGGGGAEPGQALFNGDMEPEAGAGAGAAASSAADPAIPEEVWNIKQMIKLTQEHIEALLDKFGGEHNPPSIYLEAYEEYTSKLD
ALQQREQQLLESLGNGTDFSVSSSASMDTVTSSSSSSLSVLPSSLSVFQNPTDVARSNPKSPQKPIVRVFLPNKQRTVVPARCGVTVRDS
LKKALMMRGLIPECCAVYRIQDGEKKPIGWDTDISWLTGEELHVEVLENVPLTTHNFVRKTFFTLAFCDFCRKLLFQGFRCQTCGYKFHQ
RCSTEVPLMCVNYDQLDLLFVSKFFEHHPIPQEEASLAETALTSGSSPSAPASDSIGPQILTSPSPSKSIPIPQPFRPADEDHRNQFGQR
DRSSSAPNVHINTIEPVNIDYEQAADAELAWVAETKRKLMALGPIRLEQDQTTAQLQVQKAFSIDIIRHKDSMDELFSHRSEIFGTCGEE
QKTVLQEKTESLIQQYEAISLLNSERYARLERAQVLVNQFWETYEELSPWIEETRALIAQLPSPAIDHEQLRQQQEEMRQLRESIAEHKP
HIDKLLKIGPQLKELNPEEGEMVEEKYQKAENMYAQIKEEVRQRALALDEAVSQSTQITEFHDKIEPMLETLENLSSRLRMPPLIPAEVD
KIRECISDNKSATVELEKLQPSFEALKRRGEELIGRSQGADKDLAAKEIQDKLDQMVFFWEDIKARAEEREIKFLDVLELAEKFWYDMAA
LLTTIKDTQDIVHDLESPGIDPSIIKQQVEAAETIKEETDGLHEELEFIRILGADLIFACGETEKPEVRKSIDEMNNAWENLNKTWKERL
EKLEDAMQAAVQYQDTLQAMFDWLDNTVIKLCTMPPVGTDLNTVKDQLNEMKEFKVEVYQQQIEMEKLNHQGELMLKKATDETDRDIIRE
PLTELKHLWENLGEKIAHRQHKLEGALLALGQFQHALEELMSWLTHTEELLDAQRPISGDPKVIEVELAKHHVLKNDVLAHQATVETVNK
AGNELLESSAGDDASSLRSRLEAMNQCWESVLQKTEEREQQLQSTLQQAQGFHSEIEDFLLELTRMESQLSASKPTGGLPETAREQLDTH
MELYSQLKAKEETYNQLLDKGRLMLLSRDDSGSGSKTEQSVALLEQKWHVVSSKMEERKSKLEEALNLATEFQNSLQEFINWLTLAEQSL
NIASPPSLILNTVLSQIEEHKVFANEVNAHRDQIIELDQTGNQLKFLSQKQDVVLIKNLLVSVQSRWEKVVQRSIERGRSLDDARKRAKQ
FHEAWKKLIDWLEDAESHLDSELEISNDPDKIKLQLSKHKEFQKTLGGKQPVYDTTIRTGRALKEKTLLPEDSQKLDNFLGEVRDKWDTV
CGKSVERQHKLEEALLFSGQFMDALQALVDWLYKVEPQLAEDQPVHGDLDLVMNLMDAHKVFQKELGKRTGTVQVLKRSGRELIENSRDD
TTWVKGQLQELSTRWDTVCKLSVSKQSRLEQALKQAEVFRDTVHMLLEWLSEAEQTLRFRGALPDDTEALQSLIDTHKEFMKKVEEKRVD
VNSAVAMGEVILAVCHPDCITTIKHWITIIRARFEEVLTWAKQHQQRLETALSELVANAELLEELLAWIQWAETTLIQRDQEPIPQNIDR
VKALIAEHQTFMEEMTRKQPDVDRVTKTYKRKNIEPTHAPFIEKSRSGGRKSLSQPTPPPMPILSQSEAKNPRINQLSARWQQVWLLALE
RQRKLNDALDRLEELKEFANFDFDVWRKKYMRWMNHKKSRVMDFFRRIDKDQDGKITRQEFIDGILASKFPTTKLEMTAVADIFDRDGDG
YIDYYEFVAALHPNKDAYRPTTDADKIEDEVTRQVAQCKCAKRFQVEQIGENKYRFGDSQQLRLVRILRSTVMVRVGGGWMALDEFLVKN
DPCRARGRTNIELREKFILPEGASQGMTPFRSRGRRSKPSSRAASPTRSSSSASQSNHSCTSMPSSPATPASGTKVIPSSGSKLKRPTPT
FHSSRTSLAGDTSNSSSPASTGAKTNRADPKKSASRPGSRAGSRAGSRASSRRGSDASDFDLLETQSACSDTSESSAAGGQGNSRRGLNK

--------------------------------------------------------------
>10126_10126_4_BRAF-MACF1_BRAF_chr7_140494108_ENST00000288602_MACF1_chr1_39898207_ENST00000372915_length(transcript)=7529nt_BP=1201nt
CGCCTCCCTTCCCCCTCCCCGCCCGACAGCGGCCGCTCGGGCCCCGGCTCTCGGTTATAAGATGGCGGCGCTGAGCGGTGGCGGTGGTGG
CGGCGCGGAGCCGGGCCAGGCTCTGTTCAACGGGGACATGGAGCCCGAGGCCGGCGCCGGCGCCGGCGCCGCGGCCTCTTCGGCTGCGGA
CCCTGCCATTCCGGAGGAGGTGTGGAATATCAAACAAATGATTAAGTTGACACAGGAACATATAGAGGCCCTATTGGACAAATTTGGTGG
GGAGCATAATCCACCATCAATATATCTGGAGGCCTATGAAGAATACACCAGCAAGCTAGATGCACTCCAACAAAGAGAACAACAGTTATT
GGAATCTCTGGGGAACGGAACTGATTTTTCTGTTTCTAGCTCTGCATCAATGGATACCGTTACATCTTCTTCCTCTTCTAGCCTTTCAGT
GCTACCTTCATCTCTTTCAGTTTTTCAAAATCCCACAGATGTGGCACGGAGCAACCCCAAGTCACCACAAAAACCTATCGTTAGAGTCTT
CCTGCCCAACAAACAGAGGACAGTGGTACCTGCAAGGTGTGGAGTTACAGTCCGAGACAGTCTAAAGAAAGCACTGATGATGAGAGGTCT
AATCCCAGAGTGCTGTGCTGTTTACAGAATTCAGGATGGAGAGAAGAAACCAATTGGTTGGGACACTGATATTTCCTGGCTTACTGGAGA
AGAATTGCATGTGGAAGTGTTGGAGAATGTTCCACTTACAACACACAACTTTGTACGAAAAACGTTTTTCACCTTAGCATTTTGTGACTT
TTGTCGAAAGCTGCTTTTCCAGGGTTTCCGCTGTCAAACATGTGGTTATAAATTTCACCAGCGTTGTAGTACAGAAGTTCCACTGATGTG
TGTTAATTATGACCAACTTGATTTGCTGTTTGTCTCCAAGTTCTTTGAACACCACCCAATACCACAGGAAGAGGCGTCCTTAGCAGAGAC
TGCCCTAACATCTGGATCATCCCCTTCCGCACCCGCCTCGGACTCTATTGGGCCCCAAATTCTCACCAGTCCGTCTCCTTCAAAATCCAT
TCCAATTCCACAGCCCTTCCGACCAGCAGATGAAGATCATCGAAATCAATTTGGGCAACGAGACCGATCCTCATCAGCTCCCAATGTGCA
TATAAACACAATAGAACCTGTCAATATTGATTATGAGCAAGCTGCCGATGCAGAACTAGCTTGGGTTGCTGAAACAAAACGGAAACTGAT
GGCTCTGGGTCCAATTCGCCTGGAACAGGACCAGACCACAGCTCAGCTTCAGGTACAGAAGGCTTTCTCCATTGACATTATTCGACACAA
AGATTCAATGGATGAACTCTTCAGTCACCGTAGTGAAATCTTTGGCACATGTGGGGAGGAGCAAAAAACTGTATTACAGGAAAAGACAGA
GTCTCTAATACAGCAATATGAAGCCATTAGCCTACTCAATTCAGAGCGTTATGCCCGCCTAGAGCGGGCCCAGGTCTTAGTAAACCAGTT
TTGGGAAACTTATGAAGAGCTCAGCCCCTGGATTGAGGAAACTCGGGCACTAATAGCACAGTTACCCTCTCCAGCCATTGATCATGAGCA
GCTCAGGCAGCAACAAGAGGAAATGAGGCAATTAAGGGAATCTATTGCTGAACACAAACCTCATATTGACAAACTACTAAAGATAGGCCC
ACAACTAAAGGAATTAAACCCTGAGGAAGGGGAAATGGTGGAAGAAAAATACCAGAAAGCAGAAAACATGTATGCCCAAATAAAGGAGGA
GGTGCGCCAGCGAGCCCTGGCTCTGGATGAAGCCGTGTCCCAGTCCACACAGATTACAGAGTTTCATGATAAAATTGAGCCTATGTTGGA
GACACTGGAGAATCTTTCCTCTCGCCTGCGTATGCCACCACTGATCCCTGCTGAAGTAGACAAGATCAGAGAGTGCATCAGTGACAATAA
GAGTGCCACCGTGGAGCTAGAAAAACTGCAGCCATCCTTTGAGGCCTTGAAGCGCCGTGGAGAGGAGCTTATTGGACGATCTCAGGGAGC
AGACAAGGATCTGGCTGCAAAAGAAATCCAGGATAAATTGGATCAAATGGTATTCTTCTGGGAGGACATCAAAGCTCGGGCTGAAGAACG
AGAAATCAAATTTCTTGATGTCCTTGAATTAGCAGAGAAGTTCTGGTATGACATGGCAGCTCTCCTGACCACCATCAAAGACACCCAGGA
TATTGTCCATGACTTGGAAAGCCCAGGCATTGATCCTTCCATCATCAAACAACAGGTTGAAGCTGCTGAGACTATTAAGGAAGAGACAGA
TGGTCTGCATGAAGAGCTGGAGTTTATTCGGATCCTTGGAGCAGATTTGATTTTTGCCTGTGGAGAAACTGAGAAGCCTGAAGTGAGGAA
GAGCATTGATGAGATGAATAATGCTTGGGAGAACTTAAACAAAACATGGAAAGAGAGGCTAGAAAAACTTGAGGATGCTATGCAAGCTGC
TGTGCAGTATCAGGACACTCTTCAGGCTATGTTTGACTGGCTAGATAACACTGTGATTAAACTCTGCACCATGCCCCCTGTTGGCACTGA
CCTCAATACTGTTAAAGATCAGTTAAATGAAATGAAGGAGTTCAAAGTAGAAGTTTACCAACAGCAAATTGAGATGGAGAAGCTTAATCA
CCAGGGTGAACTGATGTTAAAGAAAGCTACTGATGAGACGGACAGAGACATTATACGAGAACCACTGACAGAACTCAAACACCTCTGGGA
GAACCTGGGTGAGAAAATTGCCCACCGACAGCACAAACTAGAAGGGGCTCTGTTGGCCCTTGGTCAGTTCCAGCATGCCTTAGAGGAACT
AATGAGTTGGCTGACTCATACCGAAGAGTTGTTAGATGCTCAGAGACCAATAAGTGGAGACCCAAAAGTCATTGAAGTTGAGCTCGCAAA
GCACCATGTCCTAAAAAATGATGTTTTGGCTCATCAAGCCACAGTGGAAACAGTCAACAAAGCTGGCAATGAGCTTCTTGAATCCAGTGC
TGGAGATGATGCCAGCAGCTTAAGGAGCCGTTTGGAAGCCATGAACCAATGCTGGGAGTCAGTGTTACAGAAAACAGAGGAGAGGGAGCA
GCAGCTTCAGTCAACTCTGCAGCAGGCCCAGGGCTTCCACAGTGAAATTGAAGATTTCCTCTTGGAACTTACTAGAATGGAGAGCCAGCT
TTCTGCATCTAAGCCCACAGGAGGACTTCCTGAAACTGCTAGGGAACAGCTTGATACACATATGGAACTCTATTCCCAGCTGAAAGCCAA
GGAAGAGACTTATAATCAACTACTTGACAAGGGCAGACTCATGCTTCTAAGCCGTGACGACTCTGGGTCTGGCTCCAAGACAGAACAGAG
TGTAGCACTTTTGGAGCAGAAGTGGCATGTGGTCAGCAGTAAGATGGAAGAAAGAAAGTCAAAGCTGGAAGAGGCCCTCAACTTGGCAAC
AGAATTCCAGAATTCCCTACAAGAATTTATCAACTGGCTCACTCTAGCAGAGCAGAGTTTAAACATCGCTTCTCCACCAAGCCTGATTCT
AAATACTGTCCTTTCCCAGATAGAAGAGCACAAGGTTTTTGCTAATGAAGTAAATGCTCATCGAGACCAGATCATTGAGCTGGATCAAAC
TGGGAATCAATTAAAGTTCCTTAGCCAAAAGCAGGATGTTGTTCTGATCAAGAATTTGTTGGTGAGCGTGCAGTCTCGATGGGAGAAGGT
TGTCCAGCGATCTATTGAAAGAGGGCGATCACTAGATGATGCCAGGAAGCGGGCAAAACAATTCCATGAAGCTTGGAAAAAACTGATTGA
CTGGCTAGAAGATGCAGAGAGTCACCTGGACTCAGAACTAGAGATATCCAATGACCCAGACAAAATTAAACTTCAGCTTTCTAAGCATAA
GGAGTTTCAGAAGACTCTTGGTGGCAAGCAGCCTGTGTATGATACCACAATTAGAACTGGCAGAGCACTGAAAGAAAAGACTTTGCTTCC
CGAAGATAGTCAGAAACTTGACAATTTCCTAGGAGAAGTCAGAGACAAATGGGATACTGTTTGTGGCAAGTCTGTGGAGCGGCAGCACAA
GTTGGAGGAAGCCCTGCTCTTTTCGGGTCAGTTCATGGATGCTTTGCAGGCATTGGTTGACTGGTTATACAAGGTGGAGCCACAGCTGGC
TGAGGACCAGCCCGTGCACGGGGACCTTGACCTCGTCATGAACCTCATGGATGCACACAAGGTTTTCCAGAAGGAACTGGGAAAGCGAAC
AGGAACCGTTCAGGTCCTGAAGCGGTCAGGCCGAGAGCTGATTGAGAATAGTCGAGATGACACCACTTGGGTAAAAGGACAGCTCCAGGA
ACTGAGCACTCGCTGGGACACTGTCTGTAAACTCTCTGTTTCCAAACAAAGCCGGCTTGAGCAGGCCTTAAAACAAGCGGAAGTGTTTCG
AGACACAGTCCACATGCTGTTGGAGTGGCTTTCTGAAGCAGAGCAAACGCTTCGCTTTCGGGGAGCACTTCCTGATGACACAGAGGCCCT
GCAGTCTCTCATTGACACCCATAAGGAATTCATGAAGAAAGTAGAAGAAAAGCGAGTGGACGTTAACTCAGCAGTAGCCATGGGAGAAGT
CATCCTGGCTGTCTGCCACCCCGATTGCATCACAACCATCAAACACTGGATCACCATCATCCGAGCTCGCTTCGAGGAGGTCCTGACATG
GGCTAAGCAGCACCAGCAGCGTCTTGAAACGGCCTTGTCAGAACTGGTGGCTAATGCTGAGCTCCTGGAAGAACTTCTGGCATGGATCCA
GTGGGCTGAGACCACCCTCATTCAGCGGGATCAGGAGCCAATCCCGCAGAACATTGACCGAGTTAAAGCCCTTATCGCTGAGCATCAGAC
ATTTATGGAGGAGATGACTCGCAAACAGCCTGACGTGGACCGGGTCACCAAGACATACAAAAGGAAAAACATAGAGCCTACTCACGCGCC
TTTCATAGAGAAATCCCGCAGCGGAGGCAGGAAATCCCTAAGTCAGCCAACCCCTCCTCCCATGCCAATCCTTTCACAGTCTGAAGCAAA
AAACCCACGGATCAACCAGCTTTCTGCCCGCTGGCAGCAGGTGTGGCTGTTAGCACTGGAGCGGCAAAGGAAACTGAATGATGCCTTGGA
TCGGCTGGAGGAGTTGAAAGAATTTGCCAACTTTGACTTTGATGTCTGGAGGAAAAAGTATATGCGTTGGATGAATCACAAAAAGTCTCG
AGTGATGGATTTCTTCCGGCGCATTGATAAGGACCAGGATGGGAAGATAACACGTCAGGAGTTTATCGATGGCATTTTAGCATCCAAGTT
CCCCACCACCAAGTTAGAGATGACTGCTGTGGCTGACATTTTCGACCGAGATGGGGATGGTTACATTGATTATTATGAATTTGTGGCTGC
TCTTCATCCCAACAAGGATGCGTATCGACCAACAACCGATGCAGATAAAATCGAAGATGAGGTTACAAGACAAGTGGCTCAGTGCAAATG
TGCAAAAAGGTTTCAGGTGGAGCAGATCGGAGAGAATAAATACCGGTTTGGGGATTCTCAGCAGTTGCGGCTGGTCCGTATTCTGCGCAG
CACCGTGATGGTTCGCGTTGGTGGAGGATGGATGGCCTTGGATGAATTTTTAGTGAAAAATGATCCCTGCCGAGCACGAGGTAGAACTAA
CATTGAACTTAGAGAGAAATTCATCCTACCAGAGGGAGCATCCCAGGGAATGACCCCCTTCCGCTCACGGGGTCGAAGGTCCAAACCATC
TTCCCGGGCAGCTTCCCCTACTCGTTCCAGCTCCAGTGCTAGTCAGAGTAACCACAGCTGTACATCCATGCCATCTTCTCCAGCCACCCC
AGCCAGTGGAACCAAGGTTATCCCATCATCAGGTAGCAAGTTGAAACGACCAACACCAACTTTTCATTCTAGTCGGACATCCCTTGCTGG
TGATACCAGCAATAGTTCTTCCCCGGCCTCCACAGGTGCCAAAACTAATCGGGCAGACCCTAAAAAGTCTGCCAGTCGCCCTGGGAGTCG
GGCTGGGAGTCGAGCCGGGAGTCGAGCCAGCAGCCGGCGAGGAAGTGACGCTTCTGACTTTGACCTCTTAGAGACGCAGTCTGCTTGTTC
CGACACTTCAGAAAGCAGCGCTGCAGGGGGCCAAGGCAACTCCAGGAGAGGGCTAAACAAACCTTCCAAAATCCCAACCATGTCTAAGAA
GACCACCACTGCCTCCCCCAGGACTCCAGGTCCCAAGCGATAACACTGTCTAAGCACCCCCAAGCCACTATCCACTTTGAATCCTGCTCC
ATACATTGGGTGTATATTTATTCTGAACGGGAGAAGTTATATTGTTAAAAGTGTAAAAGAATAATTGTGTTATGAAGCTGCCTTATTTTT
TTTCTTTTTGTAAGTTACTATTTTCATGTGAATATTTATGTAGATAAAATTTGCCTCCTGGTAACCCTGTAATGGATGGGGCCCAGAAAT
GAAATATTTGAGAAAAACAAGTGAAAAGGTCAAGATACAAATGTGTATTAAAAAAAAAAAAGCCTATTAATAGGGTTTCTGCGCGGTGCA
GGGTTGTAAACCTGCTTTATCTTTTAGGATTATTCCTAAATGCATCTTCTTTATAAACTTGACTTGCTATCTCAGCAAGATAAATTATAT
TAAAAAAATAAGAATCCTGCAGTGTTTAAGGAACTCTTTTTTTGTAAATCACGGACACCTCAATTAGCAAGAACTGAGGGGAGGGCTTTT
TCCATTGTTTAATGTTTTGTGATTTTTAGCTAAAGAGAGGGAACCTCATCTAAGTAACATTTGCACATGATACAGCAAAAGGAGTTCATT
GCAATACTGTCTTTGGATATTGTTTCAGTACTGGGTGTTTAAAGGACAAATAGCTGCTAGAATTCAGGGGTAAATGTAAGTGTTCAGAAA
ACGTCAGAACATTTGGGGTTTTAAACTGATTTGTTGCTCCCTATCCAGCCTAGACACCAGTAACTCTTGTGTTCACCAGGACCCAGACCC
TTGGCAAGGGATAGGCTCGTTGGTGACATTGTGAATTTCAGATTTGTTTTATCCACTTTTTTTGCTATTTATTTAAATGGTCGATCAACT
TCCCACAAACTGAGGAATGAATTCCACGAGCCTGTTCTGAAAATGTGGACGTAAGACAAACACGTGCTCGTCCTTTAATGGAGTTCACCA
GCACACTTGTTAACCAGTCCTGTTTGCTTTCGTCTTTTTTTGTGCGTAATAAAGTCAACTGACCAAGTGACCATGAAAAGGGGCTGTCTG
GGGCTCCTGTTTTTTAGCTGCTGTTCTTCAGCTCCGACCATGTTGCTGTGTGATTATCTCAATTGGTTTTAATTGAGGCAGAAACTGAAG

>10126_10126_4_BRAF-MACF1_BRAF_chr7_140494108_ENST00000288602_MACF1_chr1_39898207_ENST00000372915_length(amino acids)=2093AA_BP=380
MAALSGGGGGGAEPGQALFNGDMEPEAGAGAGAAASSAADPAIPEEVWNIKQMIKLTQEHIEALLDKFGGEHNPPSIYLEAYEEYTSKLD
ALQQREQQLLESLGNGTDFSVSSSASMDTVTSSSSSSLSVLPSSLSVFQNPTDVARSNPKSPQKPIVRVFLPNKQRTVVPARCGVTVRDS
LKKALMMRGLIPECCAVYRIQDGEKKPIGWDTDISWLTGEELHVEVLENVPLTTHNFVRKTFFTLAFCDFCRKLLFQGFRCQTCGYKFHQ
RCSTEVPLMCVNYDQLDLLFVSKFFEHHPIPQEEASLAETALTSGSSPSAPASDSIGPQILTSPSPSKSIPIPQPFRPADEDHRNQFGQR
DRSSSAPNVHINTIEPVNIDYEQAADAELAWVAETKRKLMALGPIRLEQDQTTAQLQVQKAFSIDIIRHKDSMDELFSHRSEIFGTCGEE
QKTVLQEKTESLIQQYEAISLLNSERYARLERAQVLVNQFWETYEELSPWIEETRALIAQLPSPAIDHEQLRQQQEEMRQLRESIAEHKP
HIDKLLKIGPQLKELNPEEGEMVEEKYQKAENMYAQIKEEVRQRALALDEAVSQSTQITEFHDKIEPMLETLENLSSRLRMPPLIPAEVD
KIRECISDNKSATVELEKLQPSFEALKRRGEELIGRSQGADKDLAAKEIQDKLDQMVFFWEDIKARAEEREIKFLDVLELAEKFWYDMAA
LLTTIKDTQDIVHDLESPGIDPSIIKQQVEAAETIKEETDGLHEELEFIRILGADLIFACGETEKPEVRKSIDEMNNAWENLNKTWKERL
EKLEDAMQAAVQYQDTLQAMFDWLDNTVIKLCTMPPVGTDLNTVKDQLNEMKEFKVEVYQQQIEMEKLNHQGELMLKKATDETDRDIIRE
PLTELKHLWENLGEKIAHRQHKLEGALLALGQFQHALEELMSWLTHTEELLDAQRPISGDPKVIEVELAKHHVLKNDVLAHQATVETVNK
AGNELLESSAGDDASSLRSRLEAMNQCWESVLQKTEEREQQLQSTLQQAQGFHSEIEDFLLELTRMESQLSASKPTGGLPETAREQLDTH
MELYSQLKAKEETYNQLLDKGRLMLLSRDDSGSGSKTEQSVALLEQKWHVVSSKMEERKSKLEEALNLATEFQNSLQEFINWLTLAEQSL
NIASPPSLILNTVLSQIEEHKVFANEVNAHRDQIIELDQTGNQLKFLSQKQDVVLIKNLLVSVQSRWEKVVQRSIERGRSLDDARKRAKQ
FHEAWKKLIDWLEDAESHLDSELEISNDPDKIKLQLSKHKEFQKTLGGKQPVYDTTIRTGRALKEKTLLPEDSQKLDNFLGEVRDKWDTV
CGKSVERQHKLEEALLFSGQFMDALQALVDWLYKVEPQLAEDQPVHGDLDLVMNLMDAHKVFQKELGKRTGTVQVLKRSGRELIENSRDD
TTWVKGQLQELSTRWDTVCKLSVSKQSRLEQALKQAEVFRDTVHMLLEWLSEAEQTLRFRGALPDDTEALQSLIDTHKEFMKKVEEKRVD
VNSAVAMGEVILAVCHPDCITTIKHWITIIRARFEEVLTWAKQHQQRLETALSELVANAELLEELLAWIQWAETTLIQRDQEPIPQNIDR
VKALIAEHQTFMEEMTRKQPDVDRVTKTYKRKNIEPTHAPFIEKSRSGGRKSLSQPTPPPMPILSQSEAKNPRINQLSARWQQVWLLALE
RQRKLNDALDRLEELKEFANFDFDVWRKKYMRWMNHKKSRVMDFFRRIDKDQDGKITRQEFIDGILASKFPTTKLEMTAVADIFDRDGDG
YIDYYEFVAALHPNKDAYRPTTDADKIEDEVTRQVAQCKCAKRFQVEQIGENKYRFGDSQQLRLVRILRSTVMVRVGGGWMALDEFLVKN
DPCRARGRTNIELREKFILPEGASQGMTPFRSRGRRSKPSSRAASPTRSSSSASQSNHSCTSMPSSPATPASGTKVIPSSGSKLKRPTPT
FHSSRTSLAGDTSNSSSPASTGAKTNRADPKKSASRPGSRAGSRAGSRASSRRGSDASDFDLLETQSACSDTSESSAAGGQGNSRRGLNK

--------------------------------------------------------------
>10126_10126_5_BRAF-MACF1_BRAF_chr7_140494108_ENST00000288602_MACF1_chr1_39898207_ENST00000539005_length(transcript)=7666nt_BP=1201nt
CGCCTCCCTTCCCCCTCCCCGCCCGACAGCGGCCGCTCGGGCCCCGGCTCTCGGTTATAAGATGGCGGCGCTGAGCGGTGGCGGTGGTGG
CGGCGCGGAGCCGGGCCAGGCTCTGTTCAACGGGGACATGGAGCCCGAGGCCGGCGCCGGCGCCGGCGCCGCGGCCTCTTCGGCTGCGGA
CCCTGCCATTCCGGAGGAGGTGTGGAATATCAAACAAATGATTAAGTTGACACAGGAACATATAGAGGCCCTATTGGACAAATTTGGTGG
GGAGCATAATCCACCATCAATATATCTGGAGGCCTATGAAGAATACACCAGCAAGCTAGATGCACTCCAACAAAGAGAACAACAGTTATT
GGAATCTCTGGGGAACGGAACTGATTTTTCTGTTTCTAGCTCTGCATCAATGGATACCGTTACATCTTCTTCCTCTTCTAGCCTTTCAGT
GCTACCTTCATCTCTTTCAGTTTTTCAAAATCCCACAGATGTGGCACGGAGCAACCCCAAGTCACCACAAAAACCTATCGTTAGAGTCTT
CCTGCCCAACAAACAGAGGACAGTGGTACCTGCAAGGTGTGGAGTTACAGTCCGAGACAGTCTAAAGAAAGCACTGATGATGAGAGGTCT
AATCCCAGAGTGCTGTGCTGTTTACAGAATTCAGGATGGAGAGAAGAAACCAATTGGTTGGGACACTGATATTTCCTGGCTTACTGGAGA
AGAATTGCATGTGGAAGTGTTGGAGAATGTTCCACTTACAACACACAACTTTGTACGAAAAACGTTTTTCACCTTAGCATTTTGTGACTT
TTGTCGAAAGCTGCTTTTCCAGGGTTTCCGCTGTCAAACATGTGGTTATAAATTTCACCAGCGTTGTAGTACAGAAGTTCCACTGATGTG
TGTTAATTATGACCAACTTGATTTGCTGTTTGTCTCCAAGTTCTTTGAACACCACCCAATACCACAGGAAGAGGCGTCCTTAGCAGAGAC
TGCCCTAACATCTGGATCATCCCCTTCCGCACCCGCCTCGGACTCTATTGGGCCCCAAATTCTCACCAGTCCGTCTCCTTCAAAATCCAT
TCCAATTCCACAGCCCTTCCGACCAGCAGATGAAGATCATCGAAATCAATTTGGGCAACGAGACCGATCCTCATCAGCTCCCAATGTGCA
TATAAACACAATAGAACCTGTCAATATTGATTATGAGCAAGCTGCCGATGCAGAACTAGCTTGGGTTGCTGAAACAAAACGGAAACTGAT
GGCTCTGGGTCCAATTCGCCTGGAACAGGACCAGACCACAGCTCAGCTTCAGGTACAGAAGGCTTTCTCCATTGACATTATTCGACACAA
AGATTCAATGGATGAACTCTTCAGTCACCGTAGTGAAATCTTTGGCACATGTGGGGAGGAGCAAAAAACTGTATTACAGGAAAAGACAGA
GTCTCTAATACAGCAATATGAAGCCATTAGCCTACTCAATTCAGAGCGTTATGCCCGCCTAGAGCGGGCCCAGGTCTTAGTAAACCAGTT
TTGGGAAACTTATGAAGAGCTCAGCCCCTGGATTGAGGAAACTCGGGCACTAATAGCACAGTTACCCTCTCCAGCCATTGATCATGAGCA
GCTCAGGCAGCAACAAGAGGAAATGAGGCAATTAAGGGAATCTATTGCTGAACACAAACCTCATATTGACAAACTACTAAAGATAGGCCC
ACAACTAAAGGAATTAAACCCTGAGGAAGGGGAAATGGTGGAAGAAAAATACCAGAAAGCAGAAAACATGTATGCCCAAATAAAGGAGGA
GGTGCGCCAGCGAGCCCTGGCTCTGGATGAAGCCGTGTCCCAGTCCACACAGGTATCACAGTTTCATGATAAAATTGAGCCTATGTTGGA
GACACTGGAGAATCTTTCCTCTCGCCTGCGTATGCCACCACTGATCCCTGCTGAAGTAGACAAGATCAGAGAGTGCATCAGTGACAATAA
GAGTGCCACCGTGGAGCTAGAAAAACTGCAGCCATCCTTTGAGGCCTTGAAGCGCCGTGGAGAGGAGCTTATTGGACGATCTCAGGGAGC
AGACAAGGATCTGGCTGCAAAAGAAATCCAGGATAAATTGGATCAAATGGTATTCTTCTGGGAGGACATCAAAGCTCGGGCTGAAGAACG
AGAAATCAAATTTCTTGATGTCCTTGAATTAGCAGAGAAGTTCTGGTATGACATGGCAGCTCTCCTGACCACCATCAAAGACACCCAGGA
TATTGTCCATGACTTGGAAAGCCCAGGCATTGATCCTTCCATCATCAAACAACAGGTTGAAGCTGCTGAGACTATTAAGGAAGAGACAGA
TGGTCTGCATGAAGAGCTGGAGTTTATTCGGATCCTTGGAGCAGATTTGATTTTTGCCTGTGGAGAAACTGAGAAGCCTGAAGTGAGGAA
GAGCATTGATGAGATGAATAATGCTTGGGAGAACTTAAACAAAACATGGAAAGAGAGGCTAGAAAAACTTGAGGATGCTATGCAAGCTGC
TGTGCAGTATCAGGACACTCTTCAGGCTATGTTTGACTGGCTAGATAACACTGTGATTAAACTCTGCACCATGCCCCCTGTTGGCACTGA
CCTCAATACTGTTAAAGATCAGTTAAATGAAATGAAGGAGTTCAAAGTAGAAGTTTACCAACAGCAAATTGAGATGGAGAAGCTTAATCA
CCAGGGTGAACTGATGTTAAAGAAAGCTACTGATGAGACGGACAGAGACATTATACGAGAACCACTGACAGAACTCAAACACCTCTGGGA
GAACCTGGGTGAGAAAATTGCCCACCGACAGCACAAACTAGAAGGGGCTCTGTTGGCCCTTGGTCAGTTCCAGCATGCCTTAGAGGAACT
AATGAGTTGGCTGACTCATACCGAAGAGTTGTTAGATGCTCAGAGACCAATAAGTGGAGACCCAAAAGTCATTGAAGTTGAGCTCGCAAA
GCACCATGTCCTAAAAAATGATGTTTTGGCTCATCAAGCCACAGTGGAAACAGTCAACAAAGCTGGCAATGAGCTTCTTGAATCCAGTGC
TGGAGATGATGCCAGCAGCTTAAGGAGCCGTTTGGAAGCCATGAACCAATGCTGGGAGTCAGTGTTACAGAAAACAGAGGAGAGGGAGCA
GCAGCTTCAGTCAACTCTGCAGCAGGCCCAGGGCTTCCACAGTGAAATTGAAGATTTCCTCTTGGAACTTACTAGAATGGAGAGCCAGCT
TTCTGCATCTAAGCCCACAGGAGGACTTCCTGAAACTGCTAGGGAACAGCTTGATACACATATGGAACTCTATTCCCAGCTGAAAGCCAA
GGAAGAGACTTATAATCAACTACTTGACAAGGGCAGACTCATGCTTCTAAGCCGTGACGACTCTGGGTCTGGCTCCAAGACAGAACAGAG
TGTAGCACTTTTGGAGCAGAAGTGGCATGTGGTCAGCAGTAAGATGGAAGAAAGAAAGTCAAAGCTGGAAGAGGCCCTCAACTTGGCAAC
AGAATTCCAGAATTCCCTACAAGAATTTATCAACTGGCTCACTCTAGCAGAGCAGAGTTTAAACATCGCTTCTCCACCAAGCCTGATTCT
AAATACTGTCCTTTCCCAGATAGAAGAGCACAAGGTTTTTGCTAATGAAGTAAATGCTCATCGAGACCAGATCATTGAGCTGGATCAAAC
TGGGAATCAATTAAAGTTCCTTAGCCAAAAGCAGGATGTTGTTCTGATCAAGAATTTGTTGGTGAGCGTGCAGTCTCGATGGGAGAAGGT
TGTCCAGCGATCTATTGAAAGAGGGCGATCACTAGATGATGCCAGGAAGCGGGCAAAACAATTCCATGAAGCTTGGAAAAAACTGATTGA
CTGGCTAGAAGATGCAGAGAGTCACCTGGACTCAGAACTAGAGATATCCAATGACCCAGACAAAATTAAACTTCAGCTTTCTAAGCATAA
GGAGTTTCAGAAGACTCTTGGTGGCAAGCAGCCTGTGTATGATACCACAATTAGAACTGGCAGAGCACTGAAAGAAAAGACTTTGCTTCC
CGAAGATAGTCAGAAACTTGACAATTTCCTAGGAGAAGTCAGAGACAAATGGGATACTGTTTGTGGCAAGTCTGTGGAGCGGCAGCACAA
GTTGGAGGAAGCCCTGCTCTTTTCGGGTCAGTTCATGGATGCTTTGCAGGCATTGGTTGACTGGTTATACAAGGTGGAGCCACAGCTGGC
TGAGGACCAGCCCGTGCACGGGGACCTTGACCTCGTCATGAACCTCATGGATGCACACAAGGTTTTCCAGAAGGAACTGGGAAAGCGAAC
AGGAACCGTTCAGGTCCTGAAGCGGTCAGGCCGAGAGCTGATTGAGAATAGTCGAGATGACACCACTTGGGTAAAAGGACAGCTCCAGGA
ACTGAGCACTCGCTGGGACACTGTCTGTAAACTCTCTGTTTCCAAACAAAGCCGGCTTGAGCAGGCCTTAAAACAAGCGGAAGTGTTTCG
AGACACAGTCCACATGCTGTTGGAGTGGCTTTCTGAAGCAGAGCAAACGCTTCGCTTTCGGGGAGCACTTCCTGATGACACAGAGGCCCT
GCAGTCTCTCATTGACACCCATAAGGAATTCATGAAGAAAGTAGAAGAAAAGCGAGTGGACGTTAACTCAGCAGTAGCCATGGGAGAAGT
CATCCTGGCTGTCTGCCACCCCGATTGCATCACAACCATCAAACACTGGATCACCATCATCCGAGCTCGCTTCGAGGAGGTCCTGACATG
GGCTAAGCAGCACCAGCAGCGTCTTGAAACGGCCTTGTCAGAACTGGTGGCTAATGCTGAGCTCCTGGAAGAACTTCTGGCATGGATCCA
GTGGGCTGAGACCACCCTCATTCAGCGGGATCAGGAGCCAATCCCGCAGAACATTGACCGAGTTAAAGCCCTTATCGCTGAGCATCAGAC
ATTTATGGAGGAGATGACTCGCAAACAGCCTGACGTGGACCGGGTCACCAAGACATACAAAAGGAAAAACATAGAGCCTACTCACGCGCC
TTTCATAGAGAAATCCCGCAGCGGAGGCAGGAAATCCCTAAGTCAGCCAACCCCTCCTCCCATGCCAATCCTTTCACAGTCTGAAGCAAA
AAACCCACGGATCAACCAGCTTTCTGCCCGCTGGCAGCAGGTGTGGCTGTTAGCACTGGAGCGGCAAAGGAAACTGAATGATGCCTTGGA
TCGGCTGGAGGAGTTGAAAGAATTTGCCAACTTTGACTTTGATGTCTGGAGGAAAAAGTATATGCGTTGGATGAATCACAAAAAGTCTCG
AGTGATGGATTTCTTCCGGCGCATTGATAAGGACCAGGATGGGAAGATAACACGTCAGGAGTTTATCGATGGCATTTTAGCATCCAAGTT
CCCCACCACCAAGTTAGAGATGACTGCTGTGGCTGACATTTTCGACCGAGATGGGGATGGTTACATTGATTATTATGAATTTGTGGCTGC
TCTTCATCCCAACAAGGATGCGTATCGACCAACAACCGATGCAGATAAAATCGAAGATGAGGTTACAAGACAAGTGGCTCAGTGCAAATG
TGCAAAAAGGTTTCAGGTGGAGCAGATCGGAGAGAATAAATACCGGTTTGGGGATTCTCAGCAGTTGCGGCTGGTCCGTATTCTGCGCAG
CACCGTGATGGTTCGCGTTGGTGGAGGATGGATGGCCTTGGATGAATTTTTAGTGAAAAATGATCCCTGCCGAGCACGAGGTAGAACTAA
CATTGAACTTAGAGAGAAATTCATCCTACCAGAGGGAGCATCCCAGGGAATGACCCCCTTCCGCTCACGGGGTCGAAGGTCCAAACCATC
TTCCCGGGCAGCTTCCCCTACTCGTTCCAGCTCCAGTGCTAGTCAGAGTAACCACAGCTGTACATCCATGCCATCTTCTCCAGCCACCCC
AGCCAGTGGAACCAAGGTTATCCCATCATCAGGTAGCAAGTTGAAACGACCAACACCAACTTTTCATTCTAGTCGGACATCCCTTGCTGG
TGATACCAGCAATAGTTCTTCCCCGGCCTCCACAGGTGCCAAAACTAATCGGGCAGACCCTAAAAAGTCTGCCAGTCGCCCTGGGAGTCG
GGCTGGGAGTCGAGCCGGGAGTCGAGCCAGCAGCCGGCGAGGAAGTGACGCTTCTGACTTTGACCTCTTAGAGACGCAGTCTGCTTGTTC
CGACACTTCAGAAAGCAGCGCTGCAGGGGGCCAAGGCAACTCCAGGAGAGGGCTAAACAAACCTTCCAAAATCCCAACCATGTCTAAGAA
GACCACCACTGCCTCCCCCAGGACTCCAGGTCCCAAGCGATAACACTGTCTAAGCACCCCCAAGCCACTATCCACTTTGAATCCTGCTCC
ATACATTGGGTGTATATTTATTCTGAACGGGAGAAGTTATATTGTTAAAAGTGTAAAAGAATAATTGTGTTATGAAGCTGCCTTATTTTT
TTTCTTTTTGTAAGTTACTATTTTCATGTGAATATTTATGTAGATAAAATTTGCCTCCTGGTAACCCTGTAATGGATGGGGCCCAGAAAT
GAAATATTTGAGAAAAACAAGTGAAAAGGTCAAGATACAAATGTGTATTAAAAAAAAAAAAGCCTATTAATAGGGTTTCTGCGCGGTGCA
GGGTTGTAAACCTGCTTTATCTTTTAGGATTATTCCTAAATGCATCTTCTTTATAAACTTGACTTGCTATCTCAGCAAGATAAATTATAT
TAAAAAAATAAGAATCCTGCAGTGTTTAAGGAACTCTTTTTTTGTAAATCACGGACACCTCAATTAGCAAGAACTGAGGGGAGGGCTTTT
TCCATTGTTTAATGTTTTGTGATTTTTAGCTAAAGAGAGGGAACCTCATCTAAGTAACATTTGCACATGATACAGCAAAAGGAGTTCATT
GCAATACTGTCTTTGGATATTGTTTCAGTACTGGGTGTTTAAAGGACAAATAGCTGCTAGAATTCAGGGGTAAATGTAAGTGTTCAGAAA
ACGTCAGAACATTTGGGGTTTTAAACTGATTTGTTGCTCCCTATCCAGCCTAGACACCAGTAACTCTTGTGTTCACCAGGACCCAGACCC
TTGGCAAGGGATAGGCTCGTTGGTGACATTGTGAATTTCAGATTTGTTTTATCCACTTTTTTTGCTATTTATTTAAATGGTCGATCAACT
TCCCACAAACTGAGGAATGAATTCCACGAGCCTGTTCTGAAAATGTGGACGTAAGACAAACACGTGCTCGTCCTTTAATGGAGTTCACCA
GCACACTTGTTAACCAGTCCTGTTTGCTTTCGTCTTTTTTTGTGCGTAATAAAGTCAACTGACCAAGTGACCATGAAAAGGGGCTGTCTG
GGGCTCCTGTTTTTTAGCTGCTGTTCTTCAGCTCCGACCATGTTGCTGTGTGATTATCTCAATTGGTTTTAATTGAGGCAGAAACTGAAG
CTCTACCAATGAACTGTTTAGAAACAAGACACACTTTTGTATTAAAATTGCTTGCAGTAACAAATATTTTGTATTTCCTGATTTTCTTTT
CAACTATTACCTTATCTATAAATGTTACCCTGGGGTATAATCATGTTGTAGGTACTTAAATGCATTCCGCAAATCAAAATATCTTGATGG

>10126_10126_5_BRAF-MACF1_BRAF_chr7_140494108_ENST00000288602_MACF1_chr1_39898207_ENST00000539005_length(amino acids)=2093AA_BP=380
MAALSGGGGGGAEPGQALFNGDMEPEAGAGAGAAASSAADPAIPEEVWNIKQMIKLTQEHIEALLDKFGGEHNPPSIYLEAYEEYTSKLD
ALQQREQQLLESLGNGTDFSVSSSASMDTVTSSSSSSLSVLPSSLSVFQNPTDVARSNPKSPQKPIVRVFLPNKQRTVVPARCGVTVRDS
LKKALMMRGLIPECCAVYRIQDGEKKPIGWDTDISWLTGEELHVEVLENVPLTTHNFVRKTFFTLAFCDFCRKLLFQGFRCQTCGYKFHQ
RCSTEVPLMCVNYDQLDLLFVSKFFEHHPIPQEEASLAETALTSGSSPSAPASDSIGPQILTSPSPSKSIPIPQPFRPADEDHRNQFGQR
DRSSSAPNVHINTIEPVNIDYEQAADAELAWVAETKRKLMALGPIRLEQDQTTAQLQVQKAFSIDIIRHKDSMDELFSHRSEIFGTCGEE
QKTVLQEKTESLIQQYEAISLLNSERYARLERAQVLVNQFWETYEELSPWIEETRALIAQLPSPAIDHEQLRQQQEEMRQLRESIAEHKP
HIDKLLKIGPQLKELNPEEGEMVEEKYQKAENMYAQIKEEVRQRALALDEAVSQSTQVSQFHDKIEPMLETLENLSSRLRMPPLIPAEVD
KIRECISDNKSATVELEKLQPSFEALKRRGEELIGRSQGADKDLAAKEIQDKLDQMVFFWEDIKARAEEREIKFLDVLELAEKFWYDMAA
LLTTIKDTQDIVHDLESPGIDPSIIKQQVEAAETIKEETDGLHEELEFIRILGADLIFACGETEKPEVRKSIDEMNNAWENLNKTWKERL
EKLEDAMQAAVQYQDTLQAMFDWLDNTVIKLCTMPPVGTDLNTVKDQLNEMKEFKVEVYQQQIEMEKLNHQGELMLKKATDETDRDIIRE
PLTELKHLWENLGEKIAHRQHKLEGALLALGQFQHALEELMSWLTHTEELLDAQRPISGDPKVIEVELAKHHVLKNDVLAHQATVETVNK
AGNELLESSAGDDASSLRSRLEAMNQCWESVLQKTEEREQQLQSTLQQAQGFHSEIEDFLLELTRMESQLSASKPTGGLPETAREQLDTH
MELYSQLKAKEETYNQLLDKGRLMLLSRDDSGSGSKTEQSVALLEQKWHVVSSKMEERKSKLEEALNLATEFQNSLQEFINWLTLAEQSL
NIASPPSLILNTVLSQIEEHKVFANEVNAHRDQIIELDQTGNQLKFLSQKQDVVLIKNLLVSVQSRWEKVVQRSIERGRSLDDARKRAKQ
FHEAWKKLIDWLEDAESHLDSELEISNDPDKIKLQLSKHKEFQKTLGGKQPVYDTTIRTGRALKEKTLLPEDSQKLDNFLGEVRDKWDTV
CGKSVERQHKLEEALLFSGQFMDALQALVDWLYKVEPQLAEDQPVHGDLDLVMNLMDAHKVFQKELGKRTGTVQVLKRSGRELIENSRDD
TTWVKGQLQELSTRWDTVCKLSVSKQSRLEQALKQAEVFRDTVHMLLEWLSEAEQTLRFRGALPDDTEALQSLIDTHKEFMKKVEEKRVD
VNSAVAMGEVILAVCHPDCITTIKHWITIIRARFEEVLTWAKQHQQRLETALSELVANAELLEELLAWIQWAETTLIQRDQEPIPQNIDR
VKALIAEHQTFMEEMTRKQPDVDRVTKTYKRKNIEPTHAPFIEKSRSGGRKSLSQPTPPPMPILSQSEAKNPRINQLSARWQQVWLLALE
RQRKLNDALDRLEELKEFANFDFDVWRKKYMRWMNHKKSRVMDFFRRIDKDQDGKITRQEFIDGILASKFPTTKLEMTAVADIFDRDGDG
YIDYYEFVAALHPNKDAYRPTTDADKIEDEVTRQVAQCKCAKRFQVEQIGENKYRFGDSQQLRLVRILRSTVMVRVGGGWMALDEFLVKN
DPCRARGRTNIELREKFILPEGASQGMTPFRSRGRRSKPSSRAASPTRSSSSASQSNHSCTSMPSSPATPASGTKVIPSSGSKLKRPTPT
FHSSRTSLAGDTSNSSSPASTGAKTNRADPKKSASRPGSRAGSRAGSRASSRRGSDASDFDLLETQSACSDTSESSAAGGQGNSRRGLNK

--------------------------------------------------------------
>10126_10126_6_BRAF-MACF1_BRAF_chr7_140494108_ENST00000288602_MACF1_chr1_39898207_ENST00000545844_length(transcript)=7666nt_BP=1201nt
CGCCTCCCTTCCCCCTCCCCGCCCGACAGCGGCCGCTCGGGCCCCGGCTCTCGGTTATAAGATGGCGGCGCTGAGCGGTGGCGGTGGTGG
CGGCGCGGAGCCGGGCCAGGCTCTGTTCAACGGGGACATGGAGCCCGAGGCCGGCGCCGGCGCCGGCGCCGCGGCCTCTTCGGCTGCGGA
CCCTGCCATTCCGGAGGAGGTGTGGAATATCAAACAAATGATTAAGTTGACACAGGAACATATAGAGGCCCTATTGGACAAATTTGGTGG
GGAGCATAATCCACCATCAATATATCTGGAGGCCTATGAAGAATACACCAGCAAGCTAGATGCACTCCAACAAAGAGAACAACAGTTATT
GGAATCTCTGGGGAACGGAACTGATTTTTCTGTTTCTAGCTCTGCATCAATGGATACCGTTACATCTTCTTCCTCTTCTAGCCTTTCAGT
GCTACCTTCATCTCTTTCAGTTTTTCAAAATCCCACAGATGTGGCACGGAGCAACCCCAAGTCACCACAAAAACCTATCGTTAGAGTCTT
CCTGCCCAACAAACAGAGGACAGTGGTACCTGCAAGGTGTGGAGTTACAGTCCGAGACAGTCTAAAGAAAGCACTGATGATGAGAGGTCT
AATCCCAGAGTGCTGTGCTGTTTACAGAATTCAGGATGGAGAGAAGAAACCAATTGGTTGGGACACTGATATTTCCTGGCTTACTGGAGA
AGAATTGCATGTGGAAGTGTTGGAGAATGTTCCACTTACAACACACAACTTTGTACGAAAAACGTTTTTCACCTTAGCATTTTGTGACTT
TTGTCGAAAGCTGCTTTTCCAGGGTTTCCGCTGTCAAACATGTGGTTATAAATTTCACCAGCGTTGTAGTACAGAAGTTCCACTGATGTG
TGTTAATTATGACCAACTTGATTTGCTGTTTGTCTCCAAGTTCTTTGAACACCACCCAATACCACAGGAAGAGGCGTCCTTAGCAGAGAC
TGCCCTAACATCTGGATCATCCCCTTCCGCACCCGCCTCGGACTCTATTGGGCCCCAAATTCTCACCAGTCCGTCTCCTTCAAAATCCAT
TCCAATTCCACAGCCCTTCCGACCAGCAGATGAAGATCATCGAAATCAATTTGGGCAACGAGACCGATCCTCATCAGCTCCCAATGTGCA
TATAAACACAATAGAACCTGTCAATATTGATTATGAGCAAGCTGCCGATGCAGAACTAGCTTGGGTTGCTGAAACAAAACGGAAACTGAT
GGCTCTGGGTCCAATTCGCCTGGAACAGGACCAGACCACAGCTCAGCTTCAGGTACAGAAGGCTTTCTCCATTGACATTATTCGACACAA
AGATTCAATGGATGAACTCTTCAGTCACCGTAGTGAAATCTTTGGCACATGTGGGGAGGAGCAAAAAACTGTATTACAGGAAAAGACAGA
GTCTCTAATACAGCAATATGAAGCCATTAGCCTACTCAATTCAGAGCGTTATGCCCGCCTAGAGCGGGCCCAGGTCTTAGTAAACCAGTT
TTGGGAAACTTATGAAGAGCTCAGCCCCTGGATTGAGGAAACTCGGGCACTAATAGCACAGTTACCCTCTCCAGCCATTGATCATGAGCA
GCTCAGGCAGCAACAAGAGGAAATGAGGCAATTAAGGGAATCTATTGCTGAACACAAACCTCATATTGACAAACTACTAAAGATAGGCCC
ACAACTAAAGGAATTAAACCCTGAGGAAGGGGAAATGGTGGAAGAAAAATACCAGAAAGCAGAAAACATGTATGCCCAAATAAAGGAGGA
GGTGCGCCAGCGAGCCCTGGCTCTGGATGAAGCCGTGTCCCAGTCCACACAGATTACAGAGTTTCATGATAAAATTGAGCCTATGTTGGA
GACACTGGAGAATCTTTCCTCTCGCCTGCGTATGCCACCACTGATCCCTGCTGAAGTAGACAAGATCAGAGAGTGCATCAGTGACAATAA
GAGTGCCACCGTGGAGCTAGAAAAACTGCAGCCATCCTTTGAGGCCTTGAAGCGCCGTGGAGAGGAGCTTATTGGACGATCTCAGGGAGC
AGACAAGGATCTGGCTGCAAAAGAAATCCAGGATAAATTGGATCAAATGGTATTCTTCTGGGAGGACATCAAAGCTCGGGCTGAAGAACG
AGAAATCAAATTTCTTGATGTCCTTGAATTAGCAGAGAAGTTCTGGTATGACATGGCAGCTCTCCTGACCACCATCAAAGACACCCAGGA
TATTGTCCATGACTTGGAAAGCCCAGGCATTGATCCTTCCATCATCAAACAACAGGTTGAAGCTGCTGAGACTATTAAGGAAGAGACAGA
TGGTCTGCATGAAGAGCTGGAGTTTATTCGGATCCTTGGAGCAGATTTGATTTTTGCCTGTGGAGAAACTGAGAAGCCTGAAGTGAGGAA
GAGCATTGATGAGATGAATAATGCTTGGGAGAACTTAAACAAAACATGGAAAGAGAGGCTAGAAAAACTTGAGGATGCTATGCAAGCTGC
TGTGCAGTATCAGGACACTCTTCAGGCTATGTTTGACTGGCTAGATAACACTGTGATTAAACTCTGCACCATGCCCCCTGTTGGCACTGA
CCTCAATACTGTTAAAGATCAGTTAAATGAAATGAAGGAGTTCAAAGTAGAAGTTTACCAACAGCAAATTGAGATGGAGAAGCTTAATCA
CCAGGGTGAACTGATGTTAAAGAAAGCTACTGATGAGACGGACAGAGACATTATACGAGAACCACTGACAGAACTCAAACACCTCTGGGA
GAACCTGGGTGAGAAAATTGCCCACCGACAGCACAAACTAGAAGGGGCTCTGTTGGCCCTTGGTCAGTTCCAGCATGCCTTAGAGGAACT
AATGAGTTGGCTGACTCATACCGAAGAGTTGTTAGATGCTCAGAGACCAATAAGTGGAGACCCAAAAGTCATTGAAGTTGAGCTCGCAAA
GCACCATGTCCTAAAAAATGATGTTTTGGCTCATCAAGCCACAGTGGAAACAGTCAACAAAGCTGGCAATGAGCTTCTTGAATCCAGTGC
TGGAGATGATGCCAGCAGCTTAAGGAGCCGTTTGGAAGCCATGAACCAATGCTGGGAGTCAGTGTTACAGAAAACAGAGGAGAGGGAGCA
GCAGCTTCAGTCAACTCTGCAGCAGGCCCAGGGCTTCCACAGTGAAATTGAAGATTTCCTCTTGGAACTTACTAGAATGGAGAGCCAGCT
TTCTGCATCTAAGCCCACAGGAGGACTTCCTGAAACTGCTAGGGAACAGCTTGATACACATATGGAACTCTATTCCCAGCTGAAAGCCAA
GGAAGAGACTTATAATCAACTACTTGACAAGGGCAGACTCATGCTTCTAAGCCGTGACGACTCTGGGTCTGGCTCCAAGACAGAACAGAG
TGTAGCACTTTTGGAGCAGAAGTGGCATGTGGTCAGCAGTAAGATGGAAGAAAGAAAGTCAAAGCTGGAAGAGGCCCTCAACTTGGCAAC
AGAATTCCAGAATTCCCTACAAGAATTTATCAACTGGCTCACTCTAGCAGAGCAGAGTTTAAACATCGCTTCTCCACCAAGCCTGATTCT
AAATACTGTCCTTTCCCAGATAGAAGAGCACAAGGTTTTTGCTAATGAAGTAAATGCTCATCGAGACCAGATCATTGAGCTGGATCAAAC
TGGGAATCAATTAAAGTTCCTTAGCCAAAAGCAGGATGTTGTTCTGATCAAGAATTTGTTGGTGAGCGTGCAGTCTCGATGGGAGAAGGT
TGTCCAGCGATCTATTGAAAGAGGGCGATCACTAGATGATGCCAGGAAGCGGGCAAAACAATTCCATGAAGCTTGGAAAAAACTGATTGA
CTGGCTAGAAGATGCAGAGAGTCACCTGGACTCAGAACTAGAGATATCCAATGACCCAGACAAAATTAAACTTCAGCTTTCTAAGCATAA
GGAGTTTCAGAAGACTCTTGGTGGCAAGCAGCCTGTGTATGATACCACAATTAGAACTGGCAGAGCACTGAAAGAAAAGACTTTGCTTCC
CGAAGATAGTCAGAAACTTGACAATTTCCTAGGAGAAGTCAGAGACAAATGGGATACTGTTTGTGGCAAGTCTGTGGAGCGGCAGCACAA
GTTGGAGGAAGCCCTGCTCTTTTCGGGTCAGTTCATGGATGCTTTGCAGGCATTGGTTGACTGGTTATACAAGGTGGAGCCACAGCTGGC
TGAGGACCAGCCCGTGCACGGGGACCTTGACCTCGTCATGAACCTCATGGATGCACACAAGGTTTTCCAGAAGGAACTGGGAAAGCGAAC
AGGAACCGTTCAGGTCCTGAAGCGGTCAGGCCGAGAGCTGATTGAGAATAGTCGAGATGACACCACTTGGGTAAAAGGACAGCTCCAGGA
ACTGAGCACTCGCTGGGACACTGTCTGTAAACTCTCTGTTTCCAAACAAAGCCGGCTTGAGCAGGCCTTAAAACAAGCGGAAGTGTTTCG
AGACACAGTCCACATGCTGTTGGAGTGGCTTTCTGAAGCAGAGCAAACGCTTCGCTTTCGGGGAGCACTTCCTGATGACACAGAGGCCCT
GCAGTCTCTCATTGACACCCATAAGGAATTCATGAAGAAAGTAGAAGAAAAGCGAGTGGACGTTAACTCAGCAGTAGCCATGGGAGAAGT
CATCCTGGCTGTCTGCCACCCCGATTGCATCACAACCATCAAACACTGGATCACCATCATCCGAGCTCGCTTCGAGGAGGTCCTGACATG
GGCTAAGCAGCACCAGCAGCGTCTTGAAACGGCCTTGTCAGAACTGGTGGCTAATGCTGAGCTCCTGGAAGAACTTCTGGCATGGATCCA
GTGGGCTGAGACCACCCTCATTCAGCGGGATCAGGAGCCAATCCCGCAGAACATTGACCGAGTTAAAGCCCTTATCGCTGAGCATCAGAC
ATTTATGGAGGAGATGACTCGCAAACAGCCTGACGTGGACCGGGTCACCAAGACATACAAAAGGAAAAACATAGAGCCTACTCACGCGCC
TTTCATAGAGAAATCCCGCAGCGGAGGCAGGAAATCCCTAAGTCAGCCAACCCCTCCTCCCATGCCAATCCTTTCACAGTCTGAAGCAAA
AAACCCACGGATCAACCAGCTTTCTGCCCGCTGGCAGCAGGTGTGGCTGTTAGCACTGGAGCGGCAAAGGAAACTGAATGATGCCTTGGA
TCGGCTGGAGGAGTTGAAAGAATTTGCCAACTTTGACTTTGATGTCTGGAGGAAAAAGTATATGCGTTGGATGAATCACAAAAAGTCTCG
AGTGATGGATTTCTTCCGGCGCATTGATAAGGACCAGGATGGGAAGATAACACGTCAGGAGTTTATCGATGGCATTTTAGCATCCAAGTT
CCCCACCACCAAGTTAGAGATGACTGCTGTGGCTGACATTTTCGACCGAGATGGGGATGGTTACATTGATTATTATGAATTTGTGGCTGC
TCTTCATCCCAACAAGGATGCGTATCGACCAACAACCGATGCAGATAAAATCGAAGATGAGGTTACAAGACAAGTGGCTCAGTGCAAATG
TGCAAAAAGGTTTCAGGTGGAGCAGATCGGAGAGAATAAATACCGGTTTGGGGATTCTCAGCAGTTGCGGCTGGTCCGTATTCTGCGCAG
CACCGTGATGGTTCGCGTTGGTGGAGGATGGATGGCCTTGGATGAATTTTTAGTGAAAAATGATCCCTGCCGAGCACGAGGTAGAACTAA
CATTGAACTTAGAGAGAAATTCATCCTACCAGAGGGAGCATCCCAGGGAATGACCCCCTTCCGCTCACGGGGTCGAAGGTCCAAACCATC
TTCCCGGGCAGCTTCCCCTACTCGTTCCAGCTCCAGTGCTAGTCAGAGTAACCACAGCTGTACATCCATGCCATCTTCTCCAGCCACCCC
AGCCAGTGGAACCAAGGTTATCCCATCATCAGGTAGCAAGTTGAAACGACCAACACCAACTTTTCATTCTAGTCGGACATCCCTTGCTGG
TGATACCAGCAATAGTTCTTCCCCGGCCTCCACAGGTGCCAAAACTAATCGGGCAGACCCTAAAAAGTCTGCCAGTCGCCCTGGGAGTCG
GGCTGGGAGTCGAGCCGGGAGTCGAGCCAGCAGCCGGCGAGGAAGTGACGCTTCTGACTTTGACCTCTTAGAGACGCAGTCTGCTTGTTC
CGACACTTCAGAAAGCAGCGCTGCAGGGGGCCAAGGCAACTCCAGGAGAGGGCTAAACAAACCTTCCAAAATCCCAACCATGTCTAAGAA
GACCACCACTGCCTCCCCCAGGACTCCAGGTCCCAAGCGATAACACTGTCTAAGCACCCCCAAGCCACTATCCACTTTGAATCCTGCTCC
ATACATTGGGTGTATATTTATTCTGAACGGGAGAAGTTATATTGTTAAAAGTGTAAAAGAATAATTGTGTTATGAAGCTGCCTTATTTTT
TTTCTTTTTGTAAGTTACTATTTTCATGTGAATATTTATGTAGATAAAATTTGCCTCCTGGTAACCCTGTAATGGATGGGGCCCAGAAAT
GAAATATTTGAGAAAAACAAGTGAAAAGGTCAAGATACAAATGTGTATTAAAAAAAAAAAAGCCTATTAATAGGGTTTCTGCGCGGTGCA
GGGTTGTAAACCTGCTTTATCTTTTAGGATTATTCCTAAATGCATCTTCTTTATAAACTTGACTTGCTATCTCAGCAAGATAAATTATAT
TAAAAAAATAAGAATCCTGCAGTGTTTAAGGAACTCTTTTTTTGTAAATCACGGACACCTCAATTAGCAAGAACTGAGGGGAGGGCTTTT
TCCATTGTTTAATGTTTTGTGATTTTTAGCTAAAGAGAGGGAACCTCATCTAAGTAACATTTGCACATGATACAGCAAAAGGAGTTCATT
GCAATACTGTCTTTGGATATTGTTTCAGTACTGGGTGTTTAAAGGACAAATAGCTGCTAGAATTCAGGGGTAAATGTAAGTGTTCAGAAA
ACGTCAGAACATTTGGGGTTTTAAACTGATTTGTTGCTCCCTATCCAGCCTAGACACCAGTAACTCTTGTGTTCACCAGGACCCAGACCC
TTGGCAAGGGATAGGCTCGTTGGTGACATTGTGAATTTCAGATTTGTTTTATCCACTTTTTTTGCTATTTATTTAAATGGTCGATCAACT
TCCCACAAACTGAGGAATGAATTCCACGAGCCTGTTCTGAAAATGTGGACGTAAGACAAACACGTGCTCGTCCTTTAATGGAGTTCACCA
GCACACTTGTTAACCAGTCCTGTTTGCTTTCGTCTTTTTTTGTGCGTAATAAAGTCAACTGACCAAGTGACCATGAAAAGGGGCTGTCTG
GGGCTCCTGTTTTTTAGCTGCTGTTCTTCAGCTCCGACCATGTTGCTGTGTGATTATCTCAATTGGTTTTAATTGAGGCAGAAACTGAAG
CTCTACCAATGAACTGTTTAGAAACAAGACACACTTTTGTATTAAAATTGCTTGCAGTAACAAATATTTTGTATTTCCTGATTTTCTTTT
CAACTATTACCTTATCTATAAATGTTACCCTGGGGTATAATCATGTTGTAGGTACTTAAATGCATTCCGCAAATCAAAATATCTTGATGG

>10126_10126_6_BRAF-MACF1_BRAF_chr7_140494108_ENST00000288602_MACF1_chr1_39898207_ENST00000545844_length(amino acids)=2093AA_BP=380
MAALSGGGGGGAEPGQALFNGDMEPEAGAGAGAAASSAADPAIPEEVWNIKQMIKLTQEHIEALLDKFGGEHNPPSIYLEAYEEYTSKLD
ALQQREQQLLESLGNGTDFSVSSSASMDTVTSSSSSSLSVLPSSLSVFQNPTDVARSNPKSPQKPIVRVFLPNKQRTVVPARCGVTVRDS
LKKALMMRGLIPECCAVYRIQDGEKKPIGWDTDISWLTGEELHVEVLENVPLTTHNFVRKTFFTLAFCDFCRKLLFQGFRCQTCGYKFHQ
RCSTEVPLMCVNYDQLDLLFVSKFFEHHPIPQEEASLAETALTSGSSPSAPASDSIGPQILTSPSPSKSIPIPQPFRPADEDHRNQFGQR
DRSSSAPNVHINTIEPVNIDYEQAADAELAWVAETKRKLMALGPIRLEQDQTTAQLQVQKAFSIDIIRHKDSMDELFSHRSEIFGTCGEE
QKTVLQEKTESLIQQYEAISLLNSERYARLERAQVLVNQFWETYEELSPWIEETRALIAQLPSPAIDHEQLRQQQEEMRQLRESIAEHKP
HIDKLLKIGPQLKELNPEEGEMVEEKYQKAENMYAQIKEEVRQRALALDEAVSQSTQITEFHDKIEPMLETLENLSSRLRMPPLIPAEVD
KIRECISDNKSATVELEKLQPSFEALKRRGEELIGRSQGADKDLAAKEIQDKLDQMVFFWEDIKARAEEREIKFLDVLELAEKFWYDMAA
LLTTIKDTQDIVHDLESPGIDPSIIKQQVEAAETIKEETDGLHEELEFIRILGADLIFACGETEKPEVRKSIDEMNNAWENLNKTWKERL
EKLEDAMQAAVQYQDTLQAMFDWLDNTVIKLCTMPPVGTDLNTVKDQLNEMKEFKVEVYQQQIEMEKLNHQGELMLKKATDETDRDIIRE
PLTELKHLWENLGEKIAHRQHKLEGALLALGQFQHALEELMSWLTHTEELLDAQRPISGDPKVIEVELAKHHVLKNDVLAHQATVETVNK
AGNELLESSAGDDASSLRSRLEAMNQCWESVLQKTEEREQQLQSTLQQAQGFHSEIEDFLLELTRMESQLSASKPTGGLPETAREQLDTH
MELYSQLKAKEETYNQLLDKGRLMLLSRDDSGSGSKTEQSVALLEQKWHVVSSKMEERKSKLEEALNLATEFQNSLQEFINWLTLAEQSL
NIASPPSLILNTVLSQIEEHKVFANEVNAHRDQIIELDQTGNQLKFLSQKQDVVLIKNLLVSVQSRWEKVVQRSIERGRSLDDARKRAKQ
FHEAWKKLIDWLEDAESHLDSELEISNDPDKIKLQLSKHKEFQKTLGGKQPVYDTTIRTGRALKEKTLLPEDSQKLDNFLGEVRDKWDTV
CGKSVERQHKLEEALLFSGQFMDALQALVDWLYKVEPQLAEDQPVHGDLDLVMNLMDAHKVFQKELGKRTGTVQVLKRSGRELIENSRDD
TTWVKGQLQELSTRWDTVCKLSVSKQSRLEQALKQAEVFRDTVHMLLEWLSEAEQTLRFRGALPDDTEALQSLIDTHKEFMKKVEEKRVD
VNSAVAMGEVILAVCHPDCITTIKHWITIIRARFEEVLTWAKQHQQRLETALSELVANAELLEELLAWIQWAETTLIQRDQEPIPQNIDR
VKALIAEHQTFMEEMTRKQPDVDRVTKTYKRKNIEPTHAPFIEKSRSGGRKSLSQPTPPPMPILSQSEAKNPRINQLSARWQQVWLLALE
RQRKLNDALDRLEELKEFANFDFDVWRKKYMRWMNHKKSRVMDFFRRIDKDQDGKITRQEFIDGILASKFPTTKLEMTAVADIFDRDGDG
YIDYYEFVAALHPNKDAYRPTTDADKIEDEVTRQVAQCKCAKRFQVEQIGENKYRFGDSQQLRLVRILRSTVMVRVGGGWMALDEFLVKN
DPCRARGRTNIELREKFILPEGASQGMTPFRSRGRRSKPSSRAASPTRSSSSASQSNHSCTSMPSSPATPASGTKVIPSSGSKLKRPTPT
FHSSRTSLAGDTSNSSSPASTGAKTNRADPKKSASRPGSRAGSRAGSRASSRRGSDASDFDLLETQSACSDTSESSAAGGQGNSRRGLNK

--------------------------------------------------------------
>10126_10126_7_BRAF-MACF1_BRAF_chr7_140494108_ENST00000288602_MACF1_chr1_39898207_ENST00000564288_length(transcript)=7915nt_BP=1201nt
CGCCTCCCTTCCCCCTCCCCGCCCGACAGCGGCCGCTCGGGCCCCGGCTCTCGGTTATAAGATGGCGGCGCTGAGCGGTGGCGGTGGTGG
CGGCGCGGAGCCGGGCCAGGCTCTGTTCAACGGGGACATGGAGCCCGAGGCCGGCGCCGGCGCCGGCGCCGCGGCCTCTTCGGCTGCGGA
CCCTGCCATTCCGGAGGAGGTGTGGAATATCAAACAAATGATTAAGTTGACACAGGAACATATAGAGGCCCTATTGGACAAATTTGGTGG
GGAGCATAATCCACCATCAATATATCTGGAGGCCTATGAAGAATACACCAGCAAGCTAGATGCACTCCAACAAAGAGAACAACAGTTATT
GGAATCTCTGGGGAACGGAACTGATTTTTCTGTTTCTAGCTCTGCATCAATGGATACCGTTACATCTTCTTCCTCTTCTAGCCTTTCAGT
GCTACCTTCATCTCTTTCAGTTTTTCAAAATCCCACAGATGTGGCACGGAGCAACCCCAAGTCACCACAAAAACCTATCGTTAGAGTCTT
CCTGCCCAACAAACAGAGGACAGTGGTACCTGCAAGGTGTGGAGTTACAGTCCGAGACAGTCTAAAGAAAGCACTGATGATGAGAGGTCT
AATCCCAGAGTGCTGTGCTGTTTACAGAATTCAGGATGGAGAGAAGAAACCAATTGGTTGGGACACTGATATTTCCTGGCTTACTGGAGA
AGAATTGCATGTGGAAGTGTTGGAGAATGTTCCACTTACAACACACAACTTTGTACGAAAAACGTTTTTCACCTTAGCATTTTGTGACTT
TTGTCGAAAGCTGCTTTTCCAGGGTTTCCGCTGTCAAACATGTGGTTATAAATTTCACCAGCGTTGTAGTACAGAAGTTCCACTGATGTG
TGTTAATTATGACCAACTTGATTTGCTGTTTGTCTCCAAGTTCTTTGAACACCACCCAATACCACAGGAAGAGGCGTCCTTAGCAGAGAC
TGCCCTAACATCTGGATCATCCCCTTCCGCACCCGCCTCGGACTCTATTGGGCCCCAAATTCTCACCAGTCCGTCTCCTTCAAAATCCAT
TCCAATTCCACAGCCCTTCCGACCAGCAGATGAAGATCATCGAAATCAATTTGGGCAACGAGACCGATCCTCATCAGCTCCCAATGTGCA
TATAAACACAATAGAACCTGTCAATATTGATTATGAGCAAGCTGCCGATGCAGAACTAGCTTGGGTTGCTGAAACAAAACGGAAACTGAT
GGCTCTGGGTCCAATTCGCCTGGAACAGGACCAGACCACAGCTCAGCTTCAGGTACAGAAGGCTTTCTCCATTGACATTATTCGACACAA
AGATTCAATGGATGAACTCTTCAGTCACCGTAGTGAAATCTTTGGCACATGTGGGGAGGAGCAAAAAACTGTATTACAGGAAAAGACAGA
GTCTCTAATACAGCAATATGAAGCCATTAGCCTACTCAATTCAGAGCGTTATGCCCGCCTAGAGCGGGCCCAGGTCTTAGTAAACCAGTT
TTGGGAAACTTATGAAGAGCTCAGCCCCTGGATTGAGGAAACTCGGGCACTAATAGCACAGTTACCCTCTCCAGCCATTGATCATGAGCA
GCTCAGGCAGCAACAAGAGGAAATGAGGCAATTAAGGGAATCTATTGCTGAACACAAACCTCATATTGACAAACTACTAAAGATAGGCCC
ACAACTAAAGGAATTAAACCCTGAGGAAGGGGAAATGGTGGAAGAAAAATACCAGAAAGCAGAAAACATGTATGCCCAAATAAAGGAGGA
GGTGCGCCAGCGAGCCCTGGCTCTGGATGAAGCCGTGTCCCAGTCCACACAGTTTCATGATAAAATTGAGCCTATGTTGGAGACACTGGA
GAATCTTTCCTCTCGCCTGCGTATGCCACCACTGATCCCTGCTGAAGTAGACAAGATCAGAGAGTGCATCAGTGACAATAAGAGTGCCAC
CGTGGAGCTAGAAAAACTGCAGCCATCCTTTGAGGCCTTGAAGCGCCGTGGAGAGGAGCTTATTGGACGATCTCAGGGAGCAGACAAGGA
TCTGGCTGCAAAAGAAATCCAGGATAAATTGGATCAAATGGTATTCTTCTGGGAGGACATCAAAGCTCGGGCTGAAGAACGAGAAATCAA
ATTTCTTGATGTCCTTGAATTAGCAGAGAAGTTCTGGTATGACATGGCAGCTCTCCTGACCACCATCAAAGACACCCAGGATATTGTCCA
TGACTTGGAAAGCCCAGGCATTGATCCTTCCATCATCAAACAACAGGTTGAAGCTGCTGAGACTATTAAGGAAGAGACAGATGGTCTGCA
TGAAGAGCTGGAGTTTATTCGGATCCTTGGAGCAGATTTGATTTTTGCCTGTGGAGAAACTGAGAAGCCTGAAGTGAGGAAGAGCATTGA
TGAGATGAATAATGCTTGGGAGAACTTAAACAAAACATGGAAAGAGAGGCTAGAAAAACTTGAGGATGCTATGCAAGCTGCTGTGCAGTA
TCAGGACACTCTTCAGGCTATGTTTGACTGGCTAGATAACACTGTGATTAAACTCTGCACCATGCCCCCTGTTGGCACTGACCTCAATAC
TGTTAAAGATCAGTTAAATGAAATGAAGGAGTTCAAAGTAGAAGTTTACCAACAGCAAATTGAGATGGAGAAGCTTAATCACCAGGGTGA
ACTGATGTTAAAGAAAGCTACTGATGAGACGGACAGAGACATTATACGAGAACCACTGACAGAACTCAAACACCTCTGGGAGAACCTGGG
TGAGAAAATTGCCCACCGACAGCACAAACTAGAAGGGGCTCTGTTGGCCCTTGGTCAGTTCCAGCATGCCTTAGAGGAACTAATGAGTTG
GCTGACTCATACCGAAGAGTTGTTAGATGCTCAGAGACCAATAAGTGGAGACCCAAAAGTCATTGAAGTTGAGCTCGCAAAGCACCATGT
CCTAAAAAATGATGTTTTGGCTCATCAAGCCACAGTGGAAACAGTCAACAAAGCTGGCAATGAGCTTCTTGAATCCAGTGCTGGAGATGA
TGCCAGCAGCTTAAGGAGCCGTTTGGAAGCCATGAACCAATGCTGGGAGTCAGTGTTACAGAAAACAGAGGAGAGGGAGCAGCAGCTTCA
GTCAACTCTGCAGCAGGCCCAGGGCTTCCACAGTGAAATTGAAGATTTCCTCTTGGAACTTACTAGAATGGAGAGCCAGCTTTCTGCATC
TAAGCCCACAGGAGGACTTCCTGAAACTGCTAGGGAACAGCTTGATACACATATGGAACTCTATTCCCAGCTGAAAGCCAAGGAAGAGAC
TTATAATCAACTACTTGACAAGGGCAGACTCATGCTTCTAAGCCGTGACGACTCTGGGTCTGGCTCCAAGACAGAACAGAGTGTAGCACT
TTTGGAGCAGAAGTGGCATGTGGTCAGCAGTAAGATGGAAGAAAGAAAGTCAAAGCTGGAAGAGGCCCTCAACTTGGCAACAGAATTCCA
GAATTCCCTACAAGAATTTATCAACTGGCTCACTCTAGCAGAGCAGAGTTTAAACATCGCTTCTCCACCAAGCCTGATTCTAAATACTGT
CCTTTCCCAGATAGAAGAGCACAAGGTTTTTGCTAATGAAGTAAATGCTCATCGAGACCAGATCATTGAGCTGGATCAAACTGGGAATCA
ATTAAAGTTCCTTAGCCAAAAGCAGGATGTTGTTCTGATCAAGAATTTGTTGGTGAGCGTGCAGTCTCGATGGGAGAAGGTTGTCCAGCG
ATCTATTGAAAGAGGGCGATCACTAGATGATGCCAGGAAGCGGGCAAAACAATTCCATGAAGCTTGGAAAAAACTGATTGACTGGCTAGA
AGATGCAGAGAGTCACCTGGACTCAGAACTAGAGATATCCAATGACCCAGACAAAATTAAACTTCAGCTTTCTAAGCATAAGGAGTTTCA
GAAGACTCTTGGTGGCAAGCAGCCTGTGTATGATACCACAATTAGAACTGGCAGAGCACTGAAAGAAAAGACTTTGCTTCCCGAAGATAG
TCAGAAACTTGACAATTTCCTAGGAGAAGTCAGAGACAAATGGGATACTGTTTGTGGCAAGTCTGTGGAGCGGCAGCACAAGTTGGAGGA
AGCCCTGCTCTTTTCGGGTCAGTTCATGGATGCTTTGCAGGCATTGGTTGACTGGTTATACAAGGTGGAGCCACAGCTGGCTGAGGACCA
GCCCGTGCACGGGGACCTTGACCTCGTCATGAACCTCATGGATGCACACAAGGTTTTCCAGAAGGAACTGGGAAAGCGAACAGGAACCGT
TCAGGTCCTGAAGCGGTCAGGCCGAGAGCTGATTGAGAATAGTCGAGATGACACCACTTGGGTAAAAGGACAGCTCCAGGAACTGAGCAC
TCGCTGGGACACTGTCTGTAAACTCTCTGTTTCCAAACAAAGCCGGCTTGAGCAGGCCTTAAAACAAGCGGAAGTGTTTCGAGACACAGT
CCACATGCTGTTGGAGTGGCTTTCTGAAGCAGAGCAAACGCTTCGCTTTCGGGGAGCACTTCCTGATGACACAGAGGCCCTGCAGTCTCT
CATTGACACCCATAAGGAATTCATGAAGAAAGTAGAAGAAAAGCGAGTGGACGTTAACTCAGCAGTAGCCATGGGAGAAGTCATCCTGGC
TGTCTGCCACCCCGATTGCATCACAACCATCAAACACTGGATCACCATCATCCGAGCTCGCTTCGAGGAGGTCCTGACATGGGCTAAGCA
GCACCAGCAGCGTCTTGAAACGGCCTTGTCAGAACTGGTGGCTAATGCTGAGCTCCTGGAAGAACTTCTGGCATGGATCCAGTGGGCTGA
GACCACCCTCATTCAGCGGGATCAGGAGCCAATCCCGCAGAACATTGACCGAGTTAAAGCCCTTATCGCTGAGCATCAGACATTTATGGA
GGAGATGACTCGCAAACAGCCTGACGTGGACCGGGTCACCAAGACATACAAAAGGAAAAACATAGAGCCTACTCACGCGCCTTTCATAGA
GAAATCCCGCAGCGGAGGCAGGAAATCCCTAAGTCAGCCAACCCCTCCTCCCATGCCAATCCTTTCACAGTCTGAAGCAAAAAACCCACG
GATCAACCAGCTTTCTGCCCGCTGGCAGCAGGTGTGGCTGTTAGCACTGGAGCGGCAAAGGAAACTGAATGATGCCTTGGATCGGCTGGA
GGAGTTGAAAGAATTTGCCAACTTTGACTTTGATGTCTGGAGGAAAAAGTATATGCGTTGGATGAATCACAAAAAGTCTCGAGTGATGGA
TTTCTTCCGGCGCATTGATAAGGACCAGGATGGGAAGATAACACGTCAGGAGTTTATCGATGGCATTTTAGCATCCAAGTTCCCCACCAC
CAAGTTAGAGATGACTGCTGTGGCTGACATTTTCGACCGAGATGGGGATGGTTACATTGATTATTATGAATTTGTGGCTGCTCTTCATCC
CAACAAGGATGCGTATCGACCAACAACCGATGCAGATAAAATCGAAGATGAGGTTACAAGACAAGTGGCTCAGTGCAAATGTGCAAAAAG
GTTTCAGGTGGAGCAGATCGGAGAGAATAAATACCGGTTCTTCCTCGGCAATCAGTTTGGGGATTCTCAGCAGTTGCGGCTGGTCCGTAT
TCTGCGCAGCACCGTGATGGTTCGCGTTGGTGGAGGATGGATGGCCTTGGATGAATTTTTAGTGAAAAATGATCCCTGCCGAGTTCACCA
TCCTGGGAGTAAAATAAAGCGCTCTGATTCCAGCTCTTCGATTTCCAGTCAGTCTCCCATAGCACGAGGTAGAACTAACATTGAACTTAG
AGAGAAATTCATCCTACCAGAGGGAGCATCCCAGGGAATGACCCCCTTCCGCTCACGGGGTCGAAGGTCCAAACCATCTTCCCGGGCAGC
TTCCCCTACTCGTTCCAGCTCCAGTGCTAGTCAGAGTAACCACAGCTGTACATCCATGCCATCTTCTCCAGCCACCCCAGCCAGTGGAAC
CAAGACTTCACTTCAGTTCTCTCGCTGTTATGACAAACCCTGGTTGGTAAACAGTAAAGCTGGCACCCCTATCAGGGACAGCCATTCTCC
TGACCTCCAGCTGCCCACCCCCGAGGTTATCCCATCATCAGGTAGCAAGTTGAAACGACCAACACCAACTTTTCATTCTAGTCGGACATC
CCTTGCTGGTGATACCAGCAATAGTTCTTCCCCGGCCTCCACAGGTGCCAAAACTAATCGGGCAGACCCTAAAAAGTCTGCCAGTCGCCC
TGGGAGTCGGGCTGGGAGTCGAGCCGGGAGTCGAGCCAGCAGCCGGCGAGGAAGTGACGCTTCTGACTTTGACCTCTTAGAGACGCAGTC
TGCTTGTTCCGACACTTCAGAAAGCAGCGCTGCAGGGGGCCAAGGCAACTCCAGGAGAGGGCTAAACAAACCTTCCAAAATCCCAACCAT
GTCTAAGAAGACCACCACTGCCTCCCCCAGGACTCCAGGTCCCAAGCGATAACACTGTCTAAGCACCCCCAAGCCACTATCCACTTTGAA
TCCTGCTCCATACATTGGGTGTATATTTATTCTGAACGGGAGAAGTTATATTGTTAAAAGTGTAAAAGAATAATTGTGTTATGAAGCTGC
CTTATTTTTTTTCTTTTTGTAAGTTACTATTTTCATGTGAATATTTATGTAGATAAAATTTGCCTCCTGGTAACCCTGTAATGGATGGGG
CCCAGAAATGAAATATTTGAGAAAAACAAGTGAAAAGGTCAAGATACAAATGTGTATTAAAAAAAAAAAAGCCTATTAATAGGGTTTCTG
CGCGGTGCAGGGTTGTAAACCTGCTTTATCTTTTAGGATTATTCCTAAATGCATCTTCTTTATAAACTTGACTTGCTATCTCAGCAAGAT
AAATTATATTAAAAAAATAAGAATCCTGCAGTGTTTAAGGAACTCTTTTTTTGTAAATCACGGACACCTCAATTAGCAAGAACTGAGGGG
AGGGCTTTTTCCATTGTTTAATGTTTTGTGATTTTTAGCTAAAGAGAGGGAACCTCATCTAAGTAACATTTGCACATGATACAGCAAAAG
GAGTTCATTGCAATACTGTCTTTGGATATTGTTTCAGTACTGGGTGTTTAAAGGACAAATAGCTGCTAGAATTCAGGGGTAAATGTAAGT
GTTCAGAAAACGTCAGAACATTTGGGGTTTTAAACTGATTTGTTGCTCCCTATCCAGCCTAGACACCAGTAACTCTTGTGTTCACCAGGA
CCCAGACCCTTGGCAAGGGATAGGCTCGTTGGTGACATTGTGAATTTCAGATTTGTTTTATCCACTTTTTTTGCTATTTATTTAAATGGT
CGATCAACTTCCCACAAACTGAGGAATGAATTCCACGAGCCTGTTCTGAAAATGTGGACGTAAGACAAACACGTGCTCGTCCTTTAATGG
AGTTCACCAGCACACTTGTTAACCAGTCCTGTTTGCTTTCGTCTTTTTTTGTGCGTAATAAAGTCAACTGACCAAGTGACCATGAAAAGG
GGCTGTCTGGGGCTCCTGTTTTTTAGCTGCTGTTCTTCAGCTCCGACCATGTTGCTGTGTGATTATCTCAATTGGTTTTAATTGAGGCAG
AAACTGAAGCTCTACCAATGAACTGTTTAGAAACAAGACACACTTTTGTATTAAAATTGCTTGCAGTAACAAATATTTTGTATTTCCTGA
TTTTCTTTTCAACTATTACCTTATCTATAAATGTTACCCTGGGGTATAATCATGTTGTAGGTACTTAAATGCATTCCGCAAATCAAAATA

>10126_10126_7_BRAF-MACF1_BRAF_chr7_140494108_ENST00000288602_MACF1_chr1_39898207_ENST00000564288_length(amino acids)=2156AA_BP=380
MAALSGGGGGGAEPGQALFNGDMEPEAGAGAGAAASSAADPAIPEEVWNIKQMIKLTQEHIEALLDKFGGEHNPPSIYLEAYEEYTSKLD
ALQQREQQLLESLGNGTDFSVSSSASMDTVTSSSSSSLSVLPSSLSVFQNPTDVARSNPKSPQKPIVRVFLPNKQRTVVPARCGVTVRDS
LKKALMMRGLIPECCAVYRIQDGEKKPIGWDTDISWLTGEELHVEVLENVPLTTHNFVRKTFFTLAFCDFCRKLLFQGFRCQTCGYKFHQ
RCSTEVPLMCVNYDQLDLLFVSKFFEHHPIPQEEASLAETALTSGSSPSAPASDSIGPQILTSPSPSKSIPIPQPFRPADEDHRNQFGQR
DRSSSAPNVHINTIEPVNIDYEQAADAELAWVAETKRKLMALGPIRLEQDQTTAQLQVQKAFSIDIIRHKDSMDELFSHRSEIFGTCGEE
QKTVLQEKTESLIQQYEAISLLNSERYARLERAQVLVNQFWETYEELSPWIEETRALIAQLPSPAIDHEQLRQQQEEMRQLRESIAEHKP
HIDKLLKIGPQLKELNPEEGEMVEEKYQKAENMYAQIKEEVRQRALALDEAVSQSTQFHDKIEPMLETLENLSSRLRMPPLIPAEVDKIR
ECISDNKSATVELEKLQPSFEALKRRGEELIGRSQGADKDLAAKEIQDKLDQMVFFWEDIKARAEEREIKFLDVLELAEKFWYDMAALLT
TIKDTQDIVHDLESPGIDPSIIKQQVEAAETIKEETDGLHEELEFIRILGADLIFACGETEKPEVRKSIDEMNNAWENLNKTWKERLEKL
EDAMQAAVQYQDTLQAMFDWLDNTVIKLCTMPPVGTDLNTVKDQLNEMKEFKVEVYQQQIEMEKLNHQGELMLKKATDETDRDIIREPLT
ELKHLWENLGEKIAHRQHKLEGALLALGQFQHALEELMSWLTHTEELLDAQRPISGDPKVIEVELAKHHVLKNDVLAHQATVETVNKAGN
ELLESSAGDDASSLRSRLEAMNQCWESVLQKTEEREQQLQSTLQQAQGFHSEIEDFLLELTRMESQLSASKPTGGLPETAREQLDTHMEL
YSQLKAKEETYNQLLDKGRLMLLSRDDSGSGSKTEQSVALLEQKWHVVSSKMEERKSKLEEALNLATEFQNSLQEFINWLTLAEQSLNIA
SPPSLILNTVLSQIEEHKVFANEVNAHRDQIIELDQTGNQLKFLSQKQDVVLIKNLLVSVQSRWEKVVQRSIERGRSLDDARKRAKQFHE
AWKKLIDWLEDAESHLDSELEISNDPDKIKLQLSKHKEFQKTLGGKQPVYDTTIRTGRALKEKTLLPEDSQKLDNFLGEVRDKWDTVCGK
SVERQHKLEEALLFSGQFMDALQALVDWLYKVEPQLAEDQPVHGDLDLVMNLMDAHKVFQKELGKRTGTVQVLKRSGRELIENSRDDTTW
VKGQLQELSTRWDTVCKLSVSKQSRLEQALKQAEVFRDTVHMLLEWLSEAEQTLRFRGALPDDTEALQSLIDTHKEFMKKVEEKRVDVNS
AVAMGEVILAVCHPDCITTIKHWITIIRARFEEVLTWAKQHQQRLETALSELVANAELLEELLAWIQWAETTLIQRDQEPIPQNIDRVKA
LIAEHQTFMEEMTRKQPDVDRVTKTYKRKNIEPTHAPFIEKSRSGGRKSLSQPTPPPMPILSQSEAKNPRINQLSARWQQVWLLALERQR
KLNDALDRLEELKEFANFDFDVWRKKYMRWMNHKKSRVMDFFRRIDKDQDGKITRQEFIDGILASKFPTTKLEMTAVADIFDRDGDGYID
YYEFVAALHPNKDAYRPTTDADKIEDEVTRQVAQCKCAKRFQVEQIGENKYRFFLGNQFGDSQQLRLVRILRSTVMVRVGGGWMALDEFL
VKNDPCRVHHPGSKIKRSDSSSSISSQSPIARGRTNIELREKFILPEGASQGMTPFRSRGRRSKPSSRAASPTRSSSSASQSNHSCTSMP
SSPATPASGTKTSLQFSRCYDKPWLVNSKAGTPIRDSHSPDLQLPTPEVIPSSGSKLKRPTPTFHSSRTSLAGDTSNSSSPASTGAKTNR

--------------------------------------------------------------
>10126_10126_8_BRAF-MACF1_BRAF_chr7_140494108_ENST00000288602_MACF1_chr1_39898207_ENST00000567887_length(transcript)=7915nt_BP=1201nt
CGCCTCCCTTCCCCCTCCCCGCCCGACAGCGGCCGCTCGGGCCCCGGCTCTCGGTTATAAGATGGCGGCGCTGAGCGGTGGCGGTGGTGG
CGGCGCGGAGCCGGGCCAGGCTCTGTTCAACGGGGACATGGAGCCCGAGGCCGGCGCCGGCGCCGGCGCCGCGGCCTCTTCGGCTGCGGA
CCCTGCCATTCCGGAGGAGGTGTGGAATATCAAACAAATGATTAAGTTGACACAGGAACATATAGAGGCCCTATTGGACAAATTTGGTGG
GGAGCATAATCCACCATCAATATATCTGGAGGCCTATGAAGAATACACCAGCAAGCTAGATGCACTCCAACAAAGAGAACAACAGTTATT
GGAATCTCTGGGGAACGGAACTGATTTTTCTGTTTCTAGCTCTGCATCAATGGATACCGTTACATCTTCTTCCTCTTCTAGCCTTTCAGT
GCTACCTTCATCTCTTTCAGTTTTTCAAAATCCCACAGATGTGGCACGGAGCAACCCCAAGTCACCACAAAAACCTATCGTTAGAGTCTT
CCTGCCCAACAAACAGAGGACAGTGGTACCTGCAAGGTGTGGAGTTACAGTCCGAGACAGTCTAAAGAAAGCACTGATGATGAGAGGTCT
AATCCCAGAGTGCTGTGCTGTTTACAGAATTCAGGATGGAGAGAAGAAACCAATTGGTTGGGACACTGATATTTCCTGGCTTACTGGAGA
AGAATTGCATGTGGAAGTGTTGGAGAATGTTCCACTTACAACACACAACTTTGTACGAAAAACGTTTTTCACCTTAGCATTTTGTGACTT
TTGTCGAAAGCTGCTTTTCCAGGGTTTCCGCTGTCAAACATGTGGTTATAAATTTCACCAGCGTTGTAGTACAGAAGTTCCACTGATGTG
TGTTAATTATGACCAACTTGATTTGCTGTTTGTCTCCAAGTTCTTTGAACACCACCCAATACCACAGGAAGAGGCGTCCTTAGCAGAGAC
TGCCCTAACATCTGGATCATCCCCTTCCGCACCCGCCTCGGACTCTATTGGGCCCCAAATTCTCACCAGTCCGTCTCCTTCAAAATCCAT
TCCAATTCCACAGCCCTTCCGACCAGCAGATGAAGATCATCGAAATCAATTTGGGCAACGAGACCGATCCTCATCAGCTCCCAATGTGCA
TATAAACACAATAGAACCTGTCAATATTGATTATGAGCAAGCTGCCGATGCAGAACTAGCTTGGGTTGCTGAAACAAAACGGAAACTGAT
GGCTCTGGGTCCAATTCGCCTGGAACAGGACCAGACCACAGCTCAGCTTCAGGTACAGAAGGCTTTCTCCATTGACATTATTCGACACAA
AGATTCAATGGATGAACTCTTCAGTCACCGTAGTGAAATCTTTGGCACATGTGGGGAGGAGCAAAAAACTGTATTACAGGAAAAGACAGA
GTCTCTAATACAGCAATATGAAGCCATTAGCCTACTCAATTCAGAGCGTTATGCCCGCCTAGAGCGGGCCCAGGTCTTAGTAAACCAGTT
TTGGGAAACTTATGAAGAGCTCAGCCCCTGGATTGAGGAAACTCGGGCACTAATAGCACAGTTACCCTCTCCAGCCATTGATCATGAGCA
GCTCAGGCAGCAACAAGAGGAAATGAGGCAATTAAGGGAATCTATTGCTGAACACAAACCTCATATTGACAAACTACTAAAGATAGGCCC
ACAACTAAAGGAATTAAACCCTGAGGAAGGGGAAATGGTGGAAGAAAAATACCAGAAAGCAGAAAACATGTATGCCCAAATAAAGGAGGA
GGTGCGCCAGCGAGCCCTGGCTCTGGATGAAGCCGTGTCCCAGTCCACACAGTTTCATGATAAAATTGAGCCTATGTTGGAGACACTGGA
GAATCTTTCCTCTCGCCTGCGTATGCCACCACTGATCCCTGCTGAAGTAGACAAGATCAGAGAGTGCATCAGTGACAATAAGAGTGCCAC
CGTGGAGCTAGAAAAACTGCAGCCATCCTTTGAGGCCTTGAAGCGCCGTGGAGAGGAGCTTATTGGACGATCTCAGGGAGCAGACAAGGA
TCTGGCTGCAAAAGAAATCCAGGATAAATTGGATCAAATGGTATTCTTCTGGGAGGACATCAAAGCTCGGGCTGAAGAACGAGAAATCAA
ATTTCTTGATGTCCTTGAATTAGCAGAGAAGTTCTGGTATGACATGGCAGCTCTCCTGACCACCATCAAAGACACCCAGGATATTGTCCA
TGACTTGGAAAGCCCAGGCATTGATCCTTCCATCATCAAACAACAGGTTGAAGCTGCTGAGACTATTAAGGAAGAGACAGATGGTCTGCA
TGAAGAGCTGGAGTTTATTCGGATCCTTGGAGCAGATTTGATTTTTGCCTGTGGAGAAACTGAGAAGCCTGAAGTGAGGAAGAGCATTGA
TGAGATGAATAATGCTTGGGAGAACTTAAACAAAACATGGAAAGAGAGGCTAGAAAAACTTGAGGATGCTATGCAAGCTGCTGTGCAGTA
TCAGGACACTCTTCAGGCTATGTTTGACTGGCTAGATAACACTGTGATTAAACTCTGCACCATGCCCCCTGTTGGCACTGACCTCAATAC
TGTTAAAGATCAGTTAAATGAAATGAAGGAGTTCAAAGTAGAAGTTTACCAACAGCAAATTGAGATGGAGAAGCTTAATCACCAGGGTGA
ACTGATGTTAAAGAAAGCTACTGATGAGACGGACAGAGACATTATACGAGAACCACTGACAGAACTCAAACACCTCTGGGAGAACCTGGG
TGAGAAAATTGCCCACCGACAGCACAAACTAGAAGGGGCTCTGTTGGCCCTTGGTCAGTTCCAGCATGCCTTAGAGGAACTAATGAGTTG
GCTGACTCATACCGAAGAGTTGTTAGATGCTCAGAGACCAATAAGTGGAGACCCAAAAGTCATTGAAGTTGAGCTCGCAAAGCACCATGT
CCTAAAAAATGATGTTTTGGCTCATCAAGCCACAGTGGAAACAGTCAACAAAGCTGGCAATGAGCTTCTTGAATCCAGTGCTGGAGATGA
TGCCAGCAGCTTAAGGAGCCGTTTGGAAGCCATGAACCAATGCTGGGAGTCAGTGTTACAGAAAACAGAGGAGAGGGAGCAGCAGCTTCA
GTCAACTCTGCAGCAGGCCCAGGGCTTCCACAGTGAAATTGAAGATTTCCTCTTGGAACTTACTAGAATGGAGAGCCAGCTTTCTGCATC
TAAGCCCACAGGAGGACTTCCTGAAACTGCTAGGGAACAGCTTGATACACATATGGAACTCTATTCCCAGCTGAAAGCCAAGGAAGAGAC
TTATAATCAACTACTTGACAAGGGCAGACTCATGCTTCTAAGCCGTGACGACTCTGGGTCTGGCTCCAAGACAGAACAGAGTGTAGCACT
TTTGGAGCAGAAGTGGCATGTGGTCAGCAGTAAGATGGAAGAAAGAAAGTCAAAGCTGGAAGAGGCCCTCAACTTGGCAACAGAATTCCA
GAATTCCCTACAAGAATTTATCAACTGGCTCACTCTAGCAGAGCAGAGTTTAAACATCGCTTCTCCACCAAGCCTGATTCTAAATACTGT
CCTTTCCCAGATAGAAGAGCACAAGGTTTTTGCTAATGAAGTAAATGCTCATCGAGACCAGATCATTGAGCTGGATCAAACTGGGAATCA
ATTAAAGTTCCTTAGCCAAAAGCAGGATGTTGTTCTGATCAAGAATTTGTTGGTGAGCGTGCAGTCTCGATGGGAGAAGGTTGTCCAGCG
ATCTATTGAAAGAGGGCGATCACTAGATGATGCCAGGAAGCGGGCAAAACAATTCCATGAAGCTTGGAAAAAACTGATTGACTGGCTAGA
AGATGCAGAGAGTCACCTGGACTCAGAACTAGAGATATCCAATGACCCAGACAAAATTAAACTTCAGCTTTCTAAGCATAAGGAGTTTCA
GAAGACTCTTGGTGGCAAGCAGCCTGTGTATGATACCACAATTAGAACTGGCAGAGCACTGAAAGAAAAGACTTTGCTTCCCGAAGATAG
TCAGAAACTTGACAATTTCCTAGGAGAAGTCAGAGACAAATGGGATACTGTTTGTGGCAAGTCTGTGGAGCGGCAGCACAAGTTGGAGGA
AGCCCTGCTCTTTTCGGGTCAGTTCATGGATGCTTTGCAGGCATTGGTTGACTGGTTATACAAGGTGGAGCCACAGCTGGCTGAGGACCA
GCCCGTGCACGGGGACCTTGACCTCGTCATGAACCTCATGGATGCACACAAGGTTTTCCAGAAGGAACTGGGAAAGCGAACAGGAACCGT
TCAGGTCCTGAAGCGGTCAGGCCGAGAGCTGATTGAGAATAGTCGAGATGACACCACTTGGGTAAAAGGACAGCTCCAGGAACTGAGCAC
TCGCTGGGACACTGTCTGTAAACTCTCTGTTTCCAAACAAAGCCGGCTTGAGCAGGCCTTAAAACAAGCGGAAGTGTTTCGAGACACAGT
CCACATGCTGTTGGAGTGGCTTTCTGAAGCAGAGCAAACGCTTCGCTTTCGGGGAGCACTTCCTGATGACACAGAGGCCCTGCAGTCTCT
CATTGACACCCATAAGGAATTCATGAAGAAAGTAGAAGAAAAGCGAGTGGACGTTAACTCAGCAGTAGCCATGGGAGAAGTCATCCTGGC
TGTCTGCCACCCCGATTGCATCACAACCATCAAACACTGGATCACCATCATCCGAGCTCGCTTCGAGGAGGTCCTGACATGGGCTAAGCA
GCACCAGCAGCGTCTTGAAACGGCCTTGTCAGAACTGGTGGCTAATGCTGAGCTCCTGGAAGAACTTCTGGCATGGATCCAGTGGGCTGA
GACCACCCTCATTCAGCGGGATCAGGAGCCAATCCCGCAGAACATTGACCGAGTTAAAGCCCTTATCGCTGAGCATCAGACATTTATGGA
GGAGATGACTCGCAAACAGCCTGACGTGGACCGGGTCACCAAGACATACAAAAGGAAAAACATAGAGCCTACTCACGCGCCTTTCATAGA
GAAATCCCGCAGCGGAGGCAGGAAATCCCTAAGTCAGCCAACCCCTCCTCCCATGCCAATCCTTTCACAGTCTGAAGCAAAAAACCCACG
GATCAACCAGCTTTCTGCCCGCTGGCAGCAGGTGTGGCTGTTAGCACTGGAGCGGCAAAGGAAACTGAATGATGCCTTGGATCGGCTGGA
GGAGTTGAAAGAATTTGCCAACTTTGACTTTGATGTCTGGAGGAAAAAGTATATGCGTTGGATGAATCACAAAAAGTCTCGAGTGATGGA
TTTCTTCCGGCGCATTGATAAGGACCAGGATGGGAAGATAACACGTCAGGAGTTTATCGATGGCATTTTAGCATCCAAGTTCCCCACCAC
CAAGTTAGAGATGACTGCTGTGGCTGACATTTTCGACCGAGATGGGGATGGTTACATTGATTATTATGAATTTGTGGCTGCTCTTCATCC
CAACAAGGATGCGTATCGACCAACAACCGATGCAGATAAAATCGAAGATGAGGTTACAAGACAAGTGGCTCAGTGCAAATGTGCAAAAAG
GTTTCAGGTGGAGCAGATCGGAGAGAATAAATACCGGTTCTTCCTCGGCAATCAGTTTGGGGATTCTCAGCAGTTGCGGCTGGTCCGTAT
TCTGCGCAGCACCGTGATGGTTCGCGTTGGTGGAGGATGGATGGCCTTGGATGAATTTTTAGTGAAAAATGATCCCTGCCGAGTTCACCA
TCCTGGGAGTAAAATAAAGCGCTCTGATTCCAGCTCTTCGATTTCCAGTCAGTCTCCCATAGCACGAGGTAGAACTAACATTGAACTTAG
AGAGAAATTCATCCTACCAGAGGGAGCATCCCAGGGAATGACCCCCTTCCGCTCACGGGGTCGAAGGTCCAAACCATCTTCCCGGGCAGC
TTCCCCTACTCGTTCCAGCTCCAGTGCTAGTCAGAGTAACCACAGCTGTACATCCATGCCATCTTCTCCAGCCACCCCAGCCAGTGGAAC
CAAGACTTCACTTCAGTTCTCTCGCTGTTATGACAAACCCTGGTTGGTAAACAGTAAAGCTGGCACCCCTATCAGGGACAGCCATTCTCC
TGACCTCCAGCTGCCCACCCCCGAGGTTATCCCATCATCAGGTAGCAAGTTGAAACGACCAACACCAACTTTTCATTCTAGTCGGACATC
CCTTGCTGGTGATACCAGCAATAGTTCTTCCCCGGCCTCCACAGGTGCCAAAACTAATCGGGCAGACCCTAAAAAGTCTGCCAGTCGCCC
TGGGAGTCGGGCTGGGAGTCGAGCCGGGAGTCGAGCCAGCAGCCGGCGAGGAAGTGACGCTTCTGACTTTGACCTCTTAGAGACGCAGTC
TGCTTGTTCCGACACTTCAGAAAGCAGCGCTGCAGGGGGCCAAGGCAACTCCAGGAGAGGGCTAAACAAACCTTCCAAAATCCCAACCAT
GTCTAAGAAGACCACCACTGCCTCCCCCAGGACTCCAGGTCCCAAGCGATAACACTGTCTAAGCACCCCCAAGCCACTATCCACTTTGAA
TCCTGCTCCATACATTGGGTGTATATTTATTCTGAACGGGAGAAGTTATATTGTTAAAAGTGTAAAAGAATAATTGTGTTATGAAGCTGC
CTTATTTTTTTTCTTTTTGTAAGTTACTATTTTCATGTGAATATTTATGTAGATAAAATTTGCCTCCTGGTAACCCTGTAATGGATGGGG
CCCAGAAATGAAATATTTGAGAAAAACAAGTGAAAAGGTCAAGATACAAATGTGTATTAAAAAAAAAAAAGCCTATTAATAGGGTTTCTG
CGCGGTGCAGGGTTGTAAACCTGCTTTATCTTTTAGGATTATTCCTAAATGCATCTTCTTTATAAACTTGACTTGCTATCTCAGCAAGAT
AAATTATATTAAAAAAATAAGAATCCTGCAGTGTTTAAGGAACTCTTTTTTTGTAAATCACGGACACCTCAATTAGCAAGAACTGAGGGG
AGGGCTTTTTCCATTGTTTAATGTTTTGTGATTTTTAGCTAAAGAGAGGGAACCTCATCTAAGTAACATTTGCACATGATACAGCAAAAG
GAGTTCATTGCAATACTGTCTTTGGATATTGTTTCAGTACTGGGTGTTTAAAGGACAAATAGCTGCTAGAATTCAGGGGTAAATGTAAGT
GTTCAGAAAACGTCAGAACATTTGGGGTTTTAAACTGATTTGTTGCTCCCTATCCAGCCTAGACACCAGTAACTCTTGTGTTCACCAGGA
CCCAGACCCTTGGCAAGGGATAGGCTCGTTGGTGACATTGTGAATTTCAGATTTGTTTTATCCACTTTTTTTGCTATTTATTTAAATGGT
CGATCAACTTCCCACAAACTGAGGAATGAATTCCACGAGCCTGTTCTGAAAATGTGGACGTAAGACAAACACGTGCTCGTCCTTTAATGG
AGTTCACCAGCACACTTGTTAACCAGTCCTGTTTGCTTTCGTCTTTTTTTGTGCGTAATAAAGTCAACTGACCAAGTGACCATGAAAAGG
GGCTGTCTGGGGCTCCTGTTTTTTAGCTGCTGTTCTTCAGCTCCGACCATGTTGCTGTGTGATTATCTCAATTGGTTTTAATTGAGGCAG
AAACTGAAGCTCTACCAATGAACTGTTTAGAAACAAGACACACTTTTGTATTAAAATTGCTTGCAGTAACAAATATTTTGTATTTCCTGA
TTTTCTTTTCAACTATTACCTTATCTATAAATGTTACCCTGGGGTATAATCATGTTGTAGGTACTTAAATGCATTCCGCAAATCAAAATA

>10126_10126_8_BRAF-MACF1_BRAF_chr7_140494108_ENST00000288602_MACF1_chr1_39898207_ENST00000567887_length(amino acids)=2156AA_BP=380
MAALSGGGGGGAEPGQALFNGDMEPEAGAGAGAAASSAADPAIPEEVWNIKQMIKLTQEHIEALLDKFGGEHNPPSIYLEAYEEYTSKLD
ALQQREQQLLESLGNGTDFSVSSSASMDTVTSSSSSSLSVLPSSLSVFQNPTDVARSNPKSPQKPIVRVFLPNKQRTVVPARCGVTVRDS
LKKALMMRGLIPECCAVYRIQDGEKKPIGWDTDISWLTGEELHVEVLENVPLTTHNFVRKTFFTLAFCDFCRKLLFQGFRCQTCGYKFHQ
RCSTEVPLMCVNYDQLDLLFVSKFFEHHPIPQEEASLAETALTSGSSPSAPASDSIGPQILTSPSPSKSIPIPQPFRPADEDHRNQFGQR
DRSSSAPNVHINTIEPVNIDYEQAADAELAWVAETKRKLMALGPIRLEQDQTTAQLQVQKAFSIDIIRHKDSMDELFSHRSEIFGTCGEE
QKTVLQEKTESLIQQYEAISLLNSERYARLERAQVLVNQFWETYEELSPWIEETRALIAQLPSPAIDHEQLRQQQEEMRQLRESIAEHKP
HIDKLLKIGPQLKELNPEEGEMVEEKYQKAENMYAQIKEEVRQRALALDEAVSQSTQFHDKIEPMLETLENLSSRLRMPPLIPAEVDKIR
ECISDNKSATVELEKLQPSFEALKRRGEELIGRSQGADKDLAAKEIQDKLDQMVFFWEDIKARAEEREIKFLDVLELAEKFWYDMAALLT
TIKDTQDIVHDLESPGIDPSIIKQQVEAAETIKEETDGLHEELEFIRILGADLIFACGETEKPEVRKSIDEMNNAWENLNKTWKERLEKL
EDAMQAAVQYQDTLQAMFDWLDNTVIKLCTMPPVGTDLNTVKDQLNEMKEFKVEVYQQQIEMEKLNHQGELMLKKATDETDRDIIREPLT
ELKHLWENLGEKIAHRQHKLEGALLALGQFQHALEELMSWLTHTEELLDAQRPISGDPKVIEVELAKHHVLKNDVLAHQATVETVNKAGN
ELLESSAGDDASSLRSRLEAMNQCWESVLQKTEEREQQLQSTLQQAQGFHSEIEDFLLELTRMESQLSASKPTGGLPETAREQLDTHMEL
YSQLKAKEETYNQLLDKGRLMLLSRDDSGSGSKTEQSVALLEQKWHVVSSKMEERKSKLEEALNLATEFQNSLQEFINWLTLAEQSLNIA
SPPSLILNTVLSQIEEHKVFANEVNAHRDQIIELDQTGNQLKFLSQKQDVVLIKNLLVSVQSRWEKVVQRSIERGRSLDDARKRAKQFHE
AWKKLIDWLEDAESHLDSELEISNDPDKIKLQLSKHKEFQKTLGGKQPVYDTTIRTGRALKEKTLLPEDSQKLDNFLGEVRDKWDTVCGK
SVERQHKLEEALLFSGQFMDALQALVDWLYKVEPQLAEDQPVHGDLDLVMNLMDAHKVFQKELGKRTGTVQVLKRSGRELIENSRDDTTW
VKGQLQELSTRWDTVCKLSVSKQSRLEQALKQAEVFRDTVHMLLEWLSEAEQTLRFRGALPDDTEALQSLIDTHKEFMKKVEEKRVDVNS
AVAMGEVILAVCHPDCITTIKHWITIIRARFEEVLTWAKQHQQRLETALSELVANAELLEELLAWIQWAETTLIQRDQEPIPQNIDRVKA
LIAEHQTFMEEMTRKQPDVDRVTKTYKRKNIEPTHAPFIEKSRSGGRKSLSQPTPPPMPILSQSEAKNPRINQLSARWQQVWLLALERQR
KLNDALDRLEELKEFANFDFDVWRKKYMRWMNHKKSRVMDFFRRIDKDQDGKITRQEFIDGILASKFPTTKLEMTAVADIFDRDGDGYID
YYEFVAALHPNKDAYRPTTDADKIEDEVTRQVAQCKCAKRFQVEQIGENKYRFFLGNQFGDSQQLRLVRILRSTVMVRVGGGWMALDEFL
VKNDPCRVHHPGSKIKRSDSSSSISSQSPIARGRTNIELREKFILPEGASQGMTPFRSRGRRSKPSSRAASPTRSSSSASQSNHSCTSMP
SSPATPASGTKTSLQFSRCYDKPWLVNSKAGTPIRDSHSPDLQLPTPEVIPSSGSKLKRPTPTFHSSRTSLAGDTSNSSSPASTGAKTNR

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for BRAF-MACF1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for BRAF-MACF1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status
HgeneBRAFP15056DB08881VemurafenibInhibitorSmall moleculeApproved
HgeneBRAFP15056DB08881VemurafenibInhibitorSmall moleculeApproved
HgeneBRAFP15056DB08881VemurafenibInhibitorSmall moleculeApproved
HgeneBRAFP15056DB08896RegorafenibInhibitorSmall moleculeApproved
HgeneBRAFP15056DB08896RegorafenibInhibitorSmall moleculeApproved
HgeneBRAFP15056DB08896RegorafenibInhibitorSmall moleculeApproved
HgeneBRAFP15056DB14840RipretinibInhibitorSmall moleculeApproved
HgeneBRAFP15056DB14840RipretinibInhibitorSmall moleculeApproved
HgeneBRAFP15056DB14840RipretinibInhibitorSmall moleculeApproved
HgeneBRAFP15056DB00398SorafenibInhibitorSmall moleculeApproved|Investigational
HgeneBRAFP15056DB00398SorafenibInhibitorSmall moleculeApproved|Investigational
HgeneBRAFP15056DB00398SorafenibInhibitorSmall moleculeApproved|Investigational
HgeneBRAFP15056DB08912DabrafenibAntagonist|InhibitorSmall moleculeApproved|Investigational
HgeneBRAFP15056DB08912DabrafenibAntagonist|InhibitorSmall moleculeApproved|Investigational
HgeneBRAFP15056DB08912DabrafenibAntagonist|InhibitorSmall moleculeApproved|Investigational
HgeneBRAFP15056DB11718EncorafenibInhibitorSmall moleculeApproved|Investigational
HgeneBRAFP15056DB11718EncorafenibInhibitorSmall moleculeApproved|Investigational
HgeneBRAFP15056DB11718EncorafenibInhibitorSmall moleculeApproved|Investigational
HgeneBRAFP15056DB12010FostamatinibInhibitorSmall moleculeApproved|Investigational
HgeneBRAFP15056DB12010FostamatinibInhibitorSmall moleculeApproved|Investigational
HgeneBRAFP15056DB12010FostamatinibInhibitorSmall moleculeApproved|Investigational

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Related Diseases for BRAF-MACF1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneBRAFC0025202melanoma24CGI;CTD_human;UNIPROT
HgeneBRAFC1275081Cardio-facio-cutaneous syndrome14CLINGEN;CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
HgeneBRAFC0009402Colorectal Carcinoma8CTD_human;UNIPROT
HgeneBRAFC0028326Noonan Syndrome8CLINGEN;CTD_human;GENOMICS_ENGLAND;ORPHANET
HgeneBRAFC0238463Papillary thyroid carcinoma8CTD_human;ORPHANET
HgeneBRAFC0040136Thyroid Neoplasm6CGI;CTD_human
HgeneBRAFC0151468Thyroid Gland Follicular Adenoma6CTD_human
HgeneBRAFC0175704LEOPARD Syndrome6CLINGEN;GENOMICS_ENGLAND
HgeneBRAFC0549473Thyroid carcinoma6CGI;CTD_human
HgeneBRAFC3150970NOONAN SYNDROME 75CTD_human;GENOMICS_ENGLAND;UNIPROT
HgeneBRAFC0009404Colorectal Neoplasms4CTD_human
HgeneBRAFC3150971LEOPARD SYNDROME 34CTD_human;GENOMICS_ENGLAND;UNIPROT
HgeneBRAFC1519086Pilomyxoid astrocytoma3ORPHANET
HgeneBRAFC0004565Melanoma, B162CTD_human
HgeneBRAFC0009075Melanoma, Cloudman S912CTD_human
HgeneBRAFC0018598Melanoma, Harding-Passey2CTD_human
HgeneBRAFC0023443Hairy Cell Leukemia2CGI;ORPHANET
HgeneBRAFC0025205Melanoma, Experimental2CTD_human
HgeneBRAFC0033578Prostatic Neoplasms2CTD_human
HgeneBRAFC0152013Adenocarcinoma of lung (disorder)2CGI;CTD_human
HgeneBRAFC0376358Malignant neoplasm of prostate2CTD_human
HgeneBRAFC0587248Costello syndrome (disorder)2CLINGEN;CTD_human
HgeneBRAFC3501843Nonmedullary Thyroid Carcinoma2CTD_human
HgeneBRAFC3501844Familial Nonmedullary Thyroid Cancer2CTD_human
HgeneBRAFC0002448Ameloblastoma1CTD_human
HgeneBRAFC0004114Astrocytoma1CTD_human
HgeneBRAFC0010276Craniopharyngioma1CTD_human;ORPHANET
HgeneBRAFC0011860Diabetes Mellitus, Non-Insulin-Dependent1CTD_human
HgeneBRAFC0017638Glioma1CGI;CTD_human
HgeneBRAFC0019621Histiocytosis, Langerhans-Cell1CGI;ORPHANET
HgeneBRAFC0022665Kidney Neoplasm1CTD_human
HgeneBRAFC0023903Liver neoplasms1CTD_human
HgeneBRAFC0024232Lymphatic Metastasis1CTD_human
HgeneBRAFC0024694Mandibular Neoplasms1CTD_human
HgeneBRAFC0027659Neoplasms, Experimental1CTD_human
HgeneBRAFC0027962Melanocytic nevus1GENOMICS_ENGLAND
HgeneBRAFC0036920Sezary Syndrome1CTD_human
HgeneBRAFC0041409Turner Syndrome, Male1CTD_human
HgeneBRAFC0079773Lymphoma, T-Cell, Cutaneous1CTD_human
HgeneBRAFC0205768Subependymal Giant Cell Astrocytoma1CTD_human
HgeneBRAFC0206686Adrenocortical carcinoma1CTD_human
HgeneBRAFC0206754Neuroendocrine Tumors1CTD_human
HgeneBRAFC0259783mixed gliomas1CTD_human
HgeneBRAFC0278875Adult Craniopharyngioma1CTD_human
HgeneBRAFC0280783Juvenile Pilocytic Astrocytoma1CTD_human
HgeneBRAFC0280785Diffuse Astrocytoma1CTD_human
HgeneBRAFC0334579Anaplastic astrocytoma1CGI;CTD_human
HgeneBRAFC0334580Protoplasmic astrocytoma1CTD_human
HgeneBRAFC0334581Gemistocytic astrocytoma1CTD_human
HgeneBRAFC0334582Fibrillary Astrocytoma1CTD_human
HgeneBRAFC0334583Pilocytic Astrocytoma1CGI;CTD_human
HgeneBRAFC0338070Childhood Cerebral Astrocytoma1CTD_human
HgeneBRAFC0345904Malignant neoplasm of liver1CTD_human
HgeneBRAFC0376407Granulomatous Slack Skin1CTD_human
HgeneBRAFC0406803Syringocystadenoma Papilliferum1GENOMICS_ENGLAND
HgeneBRAFC0431128Papillary craniopharyngioma1CTD_human
HgeneBRAFC0431129Adamantinous Craniopharyngioma1CTD_human
HgeneBRAFC0547065Mixed oligoastrocytoma1CTD_human
HgeneBRAFC0555198Malignant Glioma1CTD_human
HgeneBRAFC0596263Carcinogenesis1CTD_human
HgeneBRAFC0684249Carcinoma of lung1CGI;UNIPROT
HgeneBRAFC0740457Malignant neoplasm of kidney1CTD_human
HgeneBRAFC0750935Cerebral Astrocytoma1CTD_human
HgeneBRAFC0750936Intracranial Astrocytoma1CTD_human
HgeneBRAFC0751061Craniopharyngioma, Child1CTD_human
HgeneBRAFC0920269Microsatellite Instability1CTD_human
HgeneBRAFC1527404Female Pseudo-Turner Syndrome1CTD_human
HgeneBRAFC1704230Grade I Astrocytoma1CTD_human
HgeneBRAFC1721098Replication Error Phenotype1CTD_human
HgeneBRAFC2239176Liver carcinoma1CTD_human
HgeneBRAFC4551484Leopard Syndrome 11GENOMICS_ENGLAND
HgeneBRAFC4551602Noonan Syndrome 11CTD_human
HgeneBRAFC4721532Lymphoma, Non-Hodgkin, Familial1UNIPROT
HgeneBRAFC4733333familial non-medullary thyroid cancer1GENOMICS_ENGLAND
TgeneC0036572Seizures2GENOMICS_ENGLAND
TgeneC0266463Lissencephaly2GENOMICS_ENGLAND
TgeneC1855677Brainstem dysplasia2GENOMICS_ENGLAND
TgeneC3714756Intellectual Disability2GENOMICS_ENGLAND