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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:STAT3-PLCXD1 (FusionGDB2 ID:HG6774TG55344)

Fusion Gene Summary for STAT3-PLCXD1

check button Fusion gene summary
Fusion gene informationFusion gene name: STAT3-PLCXD1
Fusion gene ID: hg6774tg55344
HgeneTgene
Gene symbol

STAT3

PLCXD1

Gene ID

6774

55344

Gene namesignal transducer and activator of transcription 3phosphatidylinositol specific phospholipase C X domain containing 1
SynonymsADMIO|ADMIO1|APRF|HIESLL0XNC01-136G2.1
Cytomap('STAT3')('PLCXD1')

17q21.2

Xp22.33 and Yp11.32-p11.31

Type of geneprotein-codingprotein-coding
Descriptionsignal transducer and activator of transcription 3DNA-binding protein APRFacute-phase response factorPI-PLC X domain-containing protein 1
Modification date2020032920200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000264657, ENST00000389272, 
ENST00000404395, ENST00000585517, 
ENST00000588969, ENST00000590776, 
Fusion gene scores* DoF score18 X 20 X 10=36003 X 4 X 2=24
# samples 233
** MAII scorelog2(23/3600*10)=-3.96829114027266
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(3/24*10)=0.321928094887362
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: STAT3 [Title/Abstract] AND PLCXD1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSTAT3(40540297)-PLCXD1(118810), # samples:1
STAT3(40540297)-PLCXD1(168810), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneSTAT3

GO:0006355

regulation of transcription, DNA-templated

15664994|17344214

HgeneSTAT3

GO:0006606

protein import into nucleus

18234692

HgeneSTAT3

GO:0010507

negative regulation of autophagy

26962683

HgeneSTAT3

GO:0010628

positive regulation of gene expression

23820254

HgeneSTAT3

GO:0030522

intracellular receptor signaling pathway

17324931

HgeneSTAT3

GO:0032355

response to estradiol

12552091

HgeneSTAT3

GO:0032870

cellular response to hormone stimulus

12552091

HgeneSTAT3

GO:0033210

leptin-mediated signaling pathway

17344214

HgeneSTAT3

GO:0035278

miRNA mediated inhibition of translation

23820254

HgeneSTAT3

GO:0044320

cellular response to leptin stimulus

17344214

HgeneSTAT3

GO:0044321

response to leptin

17344214

HgeneSTAT3

GO:0045893

positive regulation of transcription, DNA-templated

19390056

HgeneSTAT3

GO:0045944

positive regulation of transcription by RNA polymerase II

17324931|27050391|31462771

HgeneSTAT3

GO:0051726

regulation of cell cycle

17344214

HgeneSTAT3

GO:0060396

growth hormone receptor signaling pathway

10925297

HgeneSTAT3

GO:0060397

JAK-STAT cascade involved in growth hormone signaling pathway

12552091

HgeneSTAT3

GO:0070102

interleukin-6-mediated signaling pathway

12359225|12552091|17324931|24429361

HgeneSTAT3

GO:1902895

positive regulation of pri-miRNA transcription by RNA polymerase II

19390056|23820254

HgeneSTAT3

GO:2000637

positive regulation of gene silencing by miRNA

23820254



check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUSCTCGA-NC-A5HGSTAT3chr17

40540297

-PLCXD1chrX

168810

+
ChimerDB4LUSCTCGA-NC-A5HGSTAT3chr17

40540297

-PLCXD1chrY

118810

+


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Fusion Gene ORF analysis for STAT3-PLCXD1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5UTR-3UTRENST00000264657ENST00000381657STAT3chr17

40540297

-PLCXD1chrX

168810

+
5UTR-3UTRENST00000264657ENST00000399012STAT3chr17

40540297

-PLCXD1chrX

168810

+
5UTR-3UTRENST00000389272ENST00000381657STAT3chr17

40540297

-PLCXD1chrX

168810

+
5UTR-3UTRENST00000389272ENST00000399012STAT3chr17

40540297

-PLCXD1chrX

168810

+
5UTR-3UTRENST00000404395ENST00000381657STAT3chr17

40540297

-PLCXD1chrX

168810

+
5UTR-3UTRENST00000404395ENST00000399012STAT3chr17

40540297

-PLCXD1chrX

168810

+
5UTR-3UTRENST00000585517ENST00000381657STAT3chr17

40540297

-PLCXD1chrX

168810

+
5UTR-3UTRENST00000585517ENST00000399012STAT3chr17

40540297

-PLCXD1chrX

168810

+
5UTR-3UTRENST00000588969ENST00000381657STAT3chr17

40540297

-PLCXD1chrX

168810

+
5UTR-3UTRENST00000588969ENST00000399012STAT3chr17

40540297

-PLCXD1chrX

168810

+
5UTR-intronENST00000264657ENST00000381657STAT3chr17

40540297

-PLCXD1chrY

118810

+
5UTR-intronENST00000264657ENST00000381663STAT3chr17

40540297

-PLCXD1chrX

168810

+
5UTR-intronENST00000264657ENST00000381663STAT3chr17

40540297

-PLCXD1chrY

118810

+
5UTR-intronENST00000264657ENST00000399012STAT3chr17

40540297

-PLCXD1chrY

118810

+
5UTR-intronENST00000264657ENST00000484611STAT3chr17

40540297

-PLCXD1chrX

168810

+
5UTR-intronENST00000264657ENST00000484611STAT3chr17

40540297

-PLCXD1chrY

118810

+
5UTR-intronENST00000389272ENST00000381657STAT3chr17

40540297

-PLCXD1chrY

118810

+
5UTR-intronENST00000389272ENST00000381663STAT3chr17

40540297

-PLCXD1chrX

168810

+
5UTR-intronENST00000389272ENST00000381663STAT3chr17

40540297

-PLCXD1chrY

118810

+
5UTR-intronENST00000389272ENST00000399012STAT3chr17

40540297

-PLCXD1chrY

118810

+
5UTR-intronENST00000389272ENST00000484611STAT3chr17

40540297

-PLCXD1chrX

168810

+
5UTR-intronENST00000389272ENST00000484611STAT3chr17

40540297

-PLCXD1chrY

118810

+
5UTR-intronENST00000404395ENST00000381657STAT3chr17

40540297

-PLCXD1chrY

118810

+
5UTR-intronENST00000404395ENST00000381663STAT3chr17

40540297

-PLCXD1chrX

168810

+
5UTR-intronENST00000404395ENST00000381663STAT3chr17

40540297

-PLCXD1chrY

118810

+
5UTR-intronENST00000404395ENST00000399012STAT3chr17

40540297

-PLCXD1chrY

118810

+
5UTR-intronENST00000404395ENST00000484611STAT3chr17

40540297

-PLCXD1chrX

168810

+
5UTR-intronENST00000404395ENST00000484611STAT3chr17

40540297

-PLCXD1chrY

118810

+
5UTR-intronENST00000585517ENST00000381657STAT3chr17

40540297

-PLCXD1chrY

118810

+
5UTR-intronENST00000585517ENST00000381663STAT3chr17

40540297

-PLCXD1chrX

168810

+
5UTR-intronENST00000585517ENST00000381663STAT3chr17

40540297

-PLCXD1chrY

118810

+
5UTR-intronENST00000585517ENST00000399012STAT3chr17

40540297

-PLCXD1chrY

118810

+
5UTR-intronENST00000585517ENST00000484611STAT3chr17

40540297

-PLCXD1chrX

168810

+
5UTR-intronENST00000585517ENST00000484611STAT3chr17

40540297

-PLCXD1chrY

118810

+
5UTR-intronENST00000588969ENST00000381657STAT3chr17

40540297

-PLCXD1chrY

118810

+
5UTR-intronENST00000588969ENST00000381663STAT3chr17

40540297

-PLCXD1chrX

168810

+
5UTR-intronENST00000588969ENST00000381663STAT3chr17

40540297

-PLCXD1chrY

118810

+
5UTR-intronENST00000588969ENST00000399012STAT3chr17

40540297

-PLCXD1chrY

118810

+
5UTR-intronENST00000588969ENST00000484611STAT3chr17

40540297

-PLCXD1chrX

168810

+
5UTR-intronENST00000588969ENST00000484611STAT3chr17

40540297

-PLCXD1chrY

118810

+
intron-3UTRENST00000590776ENST00000381657STAT3chr17

40540297

-PLCXD1chrX

168810

+
intron-3UTRENST00000590776ENST00000399012STAT3chr17

40540297

-PLCXD1chrX

168810

+
intron-intronENST00000590776ENST00000381657STAT3chr17

40540297

-PLCXD1chrY

118810

+
intron-intronENST00000590776ENST00000381663STAT3chr17

40540297

-PLCXD1chrX

168810

+
intron-intronENST00000590776ENST00000381663STAT3chr17

40540297

-PLCXD1chrY

118810

+
intron-intronENST00000590776ENST00000399012STAT3chr17

40540297

-PLCXD1chrY

118810

+
intron-intronENST00000590776ENST00000484611STAT3chr17

40540297

-PLCXD1chrX

168810

+
intron-intronENST00000590776ENST00000484611STAT3chr17

40540297

-PLCXD1chrY

118810

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score

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Fusion Genomic Features for STAT3-PLCXD1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)


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Fusion Protein Features for STAT3-PLCXD1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/:40540297/:118810)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


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Fusion Gene Sequence for STAT3-PLCXD1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

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Fusion Gene PPI Analysis for STAT3-PLCXD1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for STAT3-PLCXD1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for STAT3-PLCXD1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneSTAT3C4721531HYPER-IgE RECURRENT INFECTION SYNDROME 1, AUTOSOMAL DOMINANT7GENOMICS_ENGLAND;UNIPROT
HgeneSTAT3C0018800Cardiomegaly3CTD_human
HgeneSTAT3C0021368Inflammation3CTD_human
HgeneSTAT3C0033578Prostatic Neoplasms3CTD_human
HgeneSTAT3C0376358Malignant neoplasm of prostate3CTD_human
HgeneSTAT3C1383860Cardiac Hypertrophy3CTD_human
HgeneSTAT3C2936739Hyper-Immunoglobulin E Syndrome, Autosomal Dominant3CTD_human;ORPHANET
HgeneSTAT3C3887645Job Syndrome3CTD_human;GENOMICS_ENGLAND;ORPHANET
HgeneSTAT3C4014795AUTOIMMUNE DISEASE, MULTISYSTEM, INFANTILE-ONSET, 13CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
HgeneSTAT3C0001418Adenocarcinoma2CTD_human
HgeneSTAT3C0003865Arthritis, Adjuvant-Induced2CTD_human
HgeneSTAT3C0007137Squamous cell carcinoma2CTD_human
HgeneSTAT3C0009324Ulcerative Colitis2CTD_human
HgeneSTAT3C0019207Hepatoma, Morris2CTD_human
HgeneSTAT3C0019208Hepatoma, Novikoff2CTD_human
HgeneSTAT3C0023904Liver Neoplasms, Experimental2CTD_human
HgeneSTAT3C0027627Neoplasm Metastasis2CTD_human
HgeneSTAT3C0030297Pancreatic Neoplasm2CTD_human
HgeneSTAT3C0033141Cardiomyopathies, Primary2CTD_human
HgeneSTAT3C0036529Myocardial Diseases, Secondary2CTD_human
HgeneSTAT3C0086404Experimental Hepatoma2CTD_human
HgeneSTAT3C0205641Adenocarcinoma, Basal Cell2CTD_human
HgeneSTAT3C0205642Adenocarcinoma, Oxyphilic2CTD_human
HgeneSTAT3C0205643Carcinoma, Cribriform2CTD_human
HgeneSTAT3C0205644Carcinoma, Granular Cell2CTD_human
HgeneSTAT3C0205645Adenocarcinoma, Tubular2CTD_human
HgeneSTAT3C0346647Malignant neoplasm of pancreas2CTD_human
HgeneSTAT3C0878544Cardiomyopathies2CTD_human
HgeneSTAT3C0971858Arthritis, Collagen-Induced2CTD_human
HgeneSTAT3C0993582Arthritis, Experimental2CTD_human
HgeneSTAT3C1955861T-Cell Large Granular Lymphocyte Leukemia2CGI;ORPHANET
HgeneSTAT3C2930809Neutropenia and hyperlymphocytosis with large granular lymphocytes2ORPHANET
HgeneSTAT3C3489795Hyper-Ige Recurrent Infection Syndrome, Autosomal Dominant2CTD_human;ORPHANET
HgeneSTAT3C0004153Atherosclerosis1CTD_human
HgeneSTAT3C0004364Autoimmune Diseases1CTD_human
HgeneSTAT3C0006142Malignant neoplasm of breast1CTD_human
HgeneSTAT3C0007097Carcinoma1CTD_human
HgeneSTAT3C0007102Malignant tumor of colon1CTD_human
HgeneSTAT3C0007131Non-Small Cell Lung Carcinoma1CTD_human
HgeneSTAT3C0007621Neoplastic Cell Transformation1CTD_human
HgeneSTAT3C0007786Brain Ischemia1CTD_human
HgeneSTAT3C0007873Uterine Cervical Neoplasm1CTD_human
HgeneSTAT3C0009375Colonic Neoplasms1CTD_human
HgeneSTAT3C0011581Depressive disorder1PSYGENET
HgeneSTAT3C0011854Diabetes Mellitus, Insulin-Dependent1CTD_human
HgeneSTAT3C0015967Fever1CTD_human
HgeneSTAT3C0016059Fibrosis1CTD_human
HgeneSTAT3C0019189Hepatitis, Chronic1CTD_human
HgeneSTAT3C0023467Leukemia, Myelocytic, Acute1CTD_human
HgeneSTAT3C0023485Precursor B-Cell Lymphoblastic Leukemia-Lymphoma1CTD_human
HgeneSTAT3C0023487Acute Promyelocytic Leukemia1ORPHANET
HgeneSTAT3C0023492Leukemia, T-Cell1CTD_human
HgeneSTAT3C0023493Adult T-Cell Lymphoma/Leukemia1CTD_human
HgeneSTAT3C0023903Liver neoplasms1CTD_human
HgeneSTAT3C0024232Lymphatic Metastasis1CTD_human
HgeneSTAT3C0024623Malignant neoplasm of stomach1CTD_human
HgeneSTAT3C0024667Animal Mammary Neoplasms1CTD_human
HgeneSTAT3C0024668Mammary Neoplasms, Experimental1CTD_human
HgeneSTAT3C0025149Medulloblastoma1CTD_human
HgeneSTAT3C0025261Memory Disorders1CTD_human
HgeneSTAT3C0026998Acute Myeloid Leukemia, M11CTD_human
HgeneSTAT3C0027659Neoplasms, Experimental1CTD_human
HgeneSTAT3C0030246Pustulosis of Palms and Soles1CTD_human
HgeneSTAT3C0032927Precancerous Conditions1CTD_human
HgeneSTAT3C0033860Psoriasis1CTD_human
HgeneSTAT3C0034069Pulmonary Fibrosis1CTD_human
HgeneSTAT3C0035126Reperfusion Injury1CTD_human
HgeneSTAT3C0038356Stomach Neoplasms1CTD_human
HgeneSTAT3C0079772T-Cell Lymphoma1CTD_human
HgeneSTAT3C0087031Juvenile-Onset Still Disease1CTD_human
HgeneSTAT3C0149519Chronic Persistent Hepatitis1CTD_human
HgeneSTAT3C0158981Neonatal diabetes mellitus1GENOMICS_ENGLAND
HgeneSTAT3C0205696Anaplastic carcinoma1CTD_human
HgeneSTAT3C0205697Carcinoma, Spindle-Cell1CTD_human
HgeneSTAT3C0205698Undifferentiated carcinoma1CTD_human
HgeneSTAT3C0205699Carcinomatosis1CTD_human
HgeneSTAT3C0205734Diabetes, Autoimmune1CTD_human
HgeneSTAT3C0205833Medullomyoblastoma1CTD_human
HgeneSTAT3C0206180Ki-1+ Anaplastic Large Cell Lymphoma1CTD_human
HgeneSTAT3C0233794Memory impairment1CTD_human
HgeneSTAT3C0235833Congenital diaphragmatic hernia1CTD_human
HgeneSTAT3C0238281Middle Cerebral Artery Syndrome1CTD_human
HgeneSTAT3C0265699Congenital hernia of foramen of Morgagni1CTD_human
HgeneSTAT3C0265700Congenital hernia of foramen of Bochdalek1CTD_human
HgeneSTAT3C0278510Childhood Medulloblastoma1CTD_human
HgeneSTAT3C0278876Adult Medulloblastoma1CTD_human
HgeneSTAT3C0282313Condition, Preneoplastic1CTD_human
HgeneSTAT3C0333641Atrophic1CTD_human
HgeneSTAT3C0342302Brittle diabetes1CTD_human
HgeneSTAT3C0345904Malignant neoplasm of liver1CTD_human
HgeneSTAT3C0520463Chronic active hepatitis1CTD_human
HgeneSTAT3C0524611Cryptogenic Chronic Hepatitis1CTD_human
HgeneSTAT3C0678222Breast Carcinoma1CTD_human
HgeneSTAT3C0740376Middle Cerebral Artery Thrombosis1CTD_human
HgeneSTAT3C0740391Middle Cerebral Artery Occlusion1CTD_human
HgeneSTAT3C0740392Infarction, Middle Cerebral Artery1CTD_human
HgeneSTAT3C0751291Desmoplastic Medulloblastoma1CTD_human
HgeneSTAT3C0751292Age-Related Memory Disorders1CTD_human
HgeneSTAT3C0751293Memory Disorder, Semantic1CTD_human
HgeneSTAT3C0751294Memory Disorder, Spatial1CTD_human
HgeneSTAT3C0751295Memory Loss1CTD_human
HgeneSTAT3C0751845Middle Cerebral Artery Embolus1CTD_human
HgeneSTAT3C0751846Left Middle Cerebral Artery Infarction1CTD_human
HgeneSTAT3C0751847Embolic Infarction, Middle Cerebral Artery1CTD_human
HgeneSTAT3C0751848Thrombotic Infarction, Middle Cerebral Artery1CTD_human
HgeneSTAT3C0751849Right Middle Cerebral Artery Infarction1CTD_human
HgeneSTAT3C0917798Cerebral Ischemia1CTD_human
HgeneSTAT3C0919267ovarian neoplasm1CTD_human
HgeneSTAT3C1140680Malignant neoplasm of ovary1CTD_human
HgeneSTAT3C1168401Squamous cell carcinoma of the head and neck1CTD_human
HgeneSTAT3C1257925Mammary Carcinoma, Animal1CTD_human
HgeneSTAT3C1257931Mammary Neoplasms, Human1CTD_human
HgeneSTAT3C1275668Melanotic medulloblastoma1CTD_human
HgeneSTAT3C1458155Mammary Neoplasms1CTD_human
HgeneSTAT3C1512709Chronic Lymphoproliferative Disorder of NK-Cells1ORPHANET
HgeneSTAT3C1563937Atherogenesis1CTD_human
HgeneSTAT3C1623038Cirrhosis1CTD_human
HgeneSTAT3C1708349Hereditary Diffuse Gastric Cancer1CTD_human
HgeneSTAT3C1800706Idiopathic Pulmonary Fibrosis1CTD_human
HgeneSTAT3C1833104DIABETES MELLITUS, PERMANENT NEONATAL1ORPHANET
HgeneSTAT3C1876165Copper-Overload Cirrhosis1CTD_human
HgeneSTAT3C1879321Acute Myeloid Leukemia (AML-M2)1CTD_human
HgeneSTAT3C1968689Hyper-Immunoglobulin E Syndrome, Autosomal Recessive1CTD_human
HgeneSTAT3C3495559Juvenile arthritis1CTD_human
HgeneSTAT3C3714758Juvenile psoriatic arthritis1CTD_human
HgeneSTAT3C3837958Diabetes Mellitus, Ketosis-Prone1CTD_human
HgeneSTAT3C4048328cervical cancer1CTD_human
HgeneSTAT3C4552091Polyarthritis, Juvenile, Rheumatoid Factor Negative1CTD_human
HgeneSTAT3C4554117Diabetes Mellitus, Sudden-Onset1CTD_human
HgeneSTAT3C4704862Polyarthritis, Juvenile, Rheumatoid Factor Positive1CTD_human
HgeneSTAT3C4704874Mammary Carcinoma, Human1CTD_human
HgeneSTAT3C4721507Alveolitis, Fibrosing1CTD_human
HgeneSTAT3C4721508Hamman-Rich Disease1CTD_human
HgeneSTAT3C4721509Usual Interstitial Pneumonia1CTD_human
HgeneSTAT3C4721952Familial Idiopathic Pulmonary Fibrosis1CTD_human