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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:SULT1C2-ACVR1 (FusionGDB2 ID:HG6819TG90)

Fusion Gene Summary for SULT1C2-ACVR1

check button Fusion gene summary
Fusion gene informationFusion gene name: SULT1C2-ACVR1
Fusion gene ID: hg6819tg90
HgeneTgene
Gene symbol

SULT1C2

ACVR1

Gene ID

6819

90

Gene namesulfotransferase family 1C member 2activin A receptor type 1
SynonymsST1C1|ST1C2|SULT1C1|humSULTC2ACTRI|ACVR1A|ACVRLK2|ALK2|FOP|SKR1|TSRI
Cytomap('SULT1C2')('ACVR1')

2q12.3

2q24.1

Type of geneprotein-codingprotein-coding
Descriptionsulfotransferase 1C2SULT1C#1sulfotransferase 1C1sulfotransferase family, cytosolic, 1C, member 1sulfotransferase family, cytosolic, 1C, member 2activin receptor type-1TGF-B superfamily receptor type Iactivin A receptor, type Iactivin A receptor, type II-like kinase 2activin receptor type Iactivin receptor-like kinase 2hydroxyalkyl-protein kinaseserine/threonine-protein kinase receptor R1
Modification date2020031320200320
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000251481, ENST00000326853, 
ENST00000409880, ENST00000437390, 
ENST00000492554, 
Fusion gene scores* DoF score3 X 1 X 2=65 X 5 X 3=75
# samples 35
** MAII scorelog2(3/6*10)=2.32192809488736log2(5/75*10)=-0.584962500721156
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: SULT1C2 [Title/Abstract] AND ACVR1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointSULT1C2(108910810)-ACVR1(158622708), # samples:1
Anticipated loss of major functional domain due to fusion event.SULT1C2-ACVR1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
SULT1C2-ACVR1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneSULT1C2

GO:0051923

sulfation

19548878|20056724

TgeneACVR1

GO:0006468

protein phosphorylation

12065756|19506109

TgeneACVR1

GO:0007179

transforming growth factor beta receptor signaling pathway

8242742

TgeneACVR1

GO:0010862

positive regulation of pathway-restricted SMAD protein phosphorylation

19506109

TgeneACVR1

GO:0018107

peptidyl-threonine phosphorylation

19736306

TgeneACVR1

GO:0030509

BMP signaling pathway

18436533

TgeneACVR1

GO:0032924

activin receptor signaling pathway

19506109

TgeneACVR1

GO:0045893

positive regulation of transcription, DNA-templated

8242742

TgeneACVR1

GO:0045944

positive regulation of transcription by RNA polymerase II

19506109

TgeneACVR1

GO:0060389

pathway-restricted SMAD protein phosphorylation

19736306

TgeneACVR1

GO:2000017

positive regulation of determination of dorsal identity

19506109


check buttonFusion gene breakpoints across SULT1C2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across ACVR1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4Non-Cancer61NSULT1C2chr2

108910810

+ACVR1chr2

158622708

-


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Fusion Gene ORF analysis for SULT1C2-ACVR1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000251481ENST00000487456SULT1C2chr2

108910810

+ACVR1chr2

158622708

-
5CDS-intronENST00000326853ENST00000487456SULT1C2chr2

108910810

+ACVR1chr2

158622708

-
5CDS-intronENST00000409880ENST00000487456SULT1C2chr2

108910810

+ACVR1chr2

158622708

-
5CDS-intronENST00000437390ENST00000487456SULT1C2chr2

108910810

+ACVR1chr2

158622708

-
In-frameENST00000251481ENST00000263640SULT1C2chr2

108910810

+ACVR1chr2

158622708

-
In-frameENST00000251481ENST00000409283SULT1C2chr2

108910810

+ACVR1chr2

158622708

-
In-frameENST00000251481ENST00000410057SULT1C2chr2

108910810

+ACVR1chr2

158622708

-
In-frameENST00000251481ENST00000434821SULT1C2chr2

108910810

+ACVR1chr2

158622708

-
In-frameENST00000326853ENST00000263640SULT1C2chr2

108910810

+ACVR1chr2

158622708

-
In-frameENST00000326853ENST00000409283SULT1C2chr2

108910810

+ACVR1chr2

158622708

-
In-frameENST00000326853ENST00000410057SULT1C2chr2

108910810

+ACVR1chr2

158622708

-
In-frameENST00000326853ENST00000434821SULT1C2chr2

108910810

+ACVR1chr2

158622708

-
In-frameENST00000409880ENST00000263640SULT1C2chr2

108910810

+ACVR1chr2

158622708

-
In-frameENST00000409880ENST00000409283SULT1C2chr2

108910810

+ACVR1chr2

158622708

-
In-frameENST00000409880ENST00000410057SULT1C2chr2

108910810

+ACVR1chr2

158622708

-
In-frameENST00000409880ENST00000434821SULT1C2chr2

108910810

+ACVR1chr2

158622708

-
In-frameENST00000437390ENST00000263640SULT1C2chr2

108910810

+ACVR1chr2

158622708

-
In-frameENST00000437390ENST00000409283SULT1C2chr2

108910810

+ACVR1chr2

158622708

-
In-frameENST00000437390ENST00000410057SULT1C2chr2

108910810

+ACVR1chr2

158622708

-
In-frameENST00000437390ENST00000434821SULT1C2chr2

108910810

+ACVR1chr2

158622708

-
intron-3CDSENST00000492554ENST00000263640SULT1C2chr2

108910810

+ACVR1chr2

158622708

-
intron-3CDSENST00000492554ENST00000409283SULT1C2chr2

108910810

+ACVR1chr2

158622708

-
intron-3CDSENST00000492554ENST00000410057SULT1C2chr2

108910810

+ACVR1chr2

158622708

-
intron-3CDSENST00000492554ENST00000434821SULT1C2chr2

108910810

+ACVR1chr2

158622708

-
intron-intronENST00000492554ENST00000487456SULT1C2chr2

108910810

+ACVR1chr2

158622708

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000251481SULT1C2chr2108910810+ENST00000263640ACVR1chr2158622708-25557304531469338
ENST00000251481SULT1C2chr2108910810+ENST00000409283ACVR1chr2158622708-25527304531469338
ENST00000251481SULT1C2chr2108910810+ENST00000434821ACVR1chr2158622708-25527304531469338
ENST00000251481SULT1C2chr2108910810+ENST00000410057ACVR1chr2158622708-16857304531469338
ENST00000326853SULT1C2chr2108910810+ENST00000263640ACVR1chr2158622708-25557304531469338
ENST00000326853SULT1C2chr2108910810+ENST00000409283ACVR1chr2158622708-25527304531469338
ENST00000326853SULT1C2chr2108910810+ENST00000434821ACVR1chr2158622708-25527304531469338
ENST00000326853SULT1C2chr2108910810+ENST00000410057ACVR1chr2158622708-16857304531469338
ENST00000437390SULT1C2chr2108910810+ENST00000263640ACVR1chr2158622708-22794541771193338
ENST00000437390SULT1C2chr2108910810+ENST00000409283ACVR1chr2158622708-22764541771193338
ENST00000437390SULT1C2chr2108910810+ENST00000434821ACVR1chr2158622708-22764541771193338
ENST00000437390SULT1C2chr2108910810+ENST00000410057ACVR1chr2158622708-14094541771193338
ENST00000409880SULT1C2chr2108910810+ENST00000263640ACVR1chr2158622708-22794541771193338
ENST00000409880SULT1C2chr2108910810+ENST00000409283ACVR1chr2158622708-22764541771193338
ENST00000409880SULT1C2chr2108910810+ENST00000434821ACVR1chr2158622708-22764541771193338
ENST00000409880SULT1C2chr2108910810+ENST00000410057ACVR1chr2158622708-14094541771193338

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000251481ENST00000263640SULT1C2chr2108910810+ACVR1chr2158622708-0.0007491130.9992508
ENST00000251481ENST00000409283SULT1C2chr2108910810+ACVR1chr2158622708-0.0007528770.9992472
ENST00000251481ENST00000434821SULT1C2chr2108910810+ACVR1chr2158622708-0.0007528770.9992472
ENST00000251481ENST00000410057SULT1C2chr2108910810+ACVR1chr2158622708-0.0032355740.9967644
ENST00000326853ENST00000263640SULT1C2chr2108910810+ACVR1chr2158622708-0.0007491130.9992508
ENST00000326853ENST00000409283SULT1C2chr2108910810+ACVR1chr2158622708-0.0007528770.9992472
ENST00000326853ENST00000434821SULT1C2chr2108910810+ACVR1chr2158622708-0.0007528770.9992472
ENST00000326853ENST00000410057SULT1C2chr2108910810+ACVR1chr2158622708-0.0032355740.9967644
ENST00000437390ENST00000263640SULT1C2chr2108910810+ACVR1chr2158622708-0.0006678410.99933213
ENST00000437390ENST00000409283SULT1C2chr2108910810+ACVR1chr2158622708-0.0006742810.99932575
ENST00000437390ENST00000434821SULT1C2chr2108910810+ACVR1chr2158622708-0.0006742810.99932575
ENST00000437390ENST00000410057SULT1C2chr2108910810+ACVR1chr2158622708-0.0038234170.9961766
ENST00000409880ENST00000263640SULT1C2chr2108910810+ACVR1chr2158622708-0.0006678410.99933213
ENST00000409880ENST00000409283SULT1C2chr2108910810+ACVR1chr2158622708-0.0006742810.99932575
ENST00000409880ENST00000434821SULT1C2chr2108910810+ACVR1chr2158622708-0.0006742810.99932575
ENST00000409880ENST00000410057SULT1C2chr2108910810+ACVR1chr2158622708-0.0038234170.9961766

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Fusion Genomic Features for SULT1C2-ACVR1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for SULT1C2-ACVR1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr2:108910810/chr2:158622708)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSULT1C2chr2:108910810chr2:158622708ENST00000251481+3849_5492297.0Nucleotide bindingNote=PAPS
HgeneSULT1C2chr2:108910810chr2:158622708ENST00000326853+3949_5492308.0Nucleotide bindingNote=PAPS

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSULT1C2chr2:108910810chr2:158622708ENST00000251481+38228_23392297.0Nucleotide bindingNote=PAPS
HgeneSULT1C2chr2:108910810chr2:158622708ENST00000251481+38256_26092297.0Nucleotide bindingNote=PAPS
HgeneSULT1C2chr2:108910810chr2:158622708ENST00000326853+39228_23392308.0Nucleotide bindingNote=PAPS
HgeneSULT1C2chr2:108910810chr2:158622708ENST00000326853+39256_26092308.0Nucleotide bindingNote=PAPS
HgeneSULT1C2chr2:108910810chr2:158622708ENST00000251481+38107_10992297.0RegionSubstrate binding
HgeneSULT1C2chr2:108910810chr2:158622708ENST00000326853+39107_10992308.0RegionSubstrate binding
TgeneACVR1chr2:108910810chr2:158622708ENST00000263640611178_207263510.0DomainGS
TgeneACVR1chr2:108910810chr2:158622708ENST00000263640611208_502263510.0DomainProtein kinase
TgeneACVR1chr2:108910810chr2:158622708ENST00000409283510178_207263510.0DomainGS
TgeneACVR1chr2:108910810chr2:158622708ENST00000409283510208_502263510.0DomainProtein kinase
TgeneACVR1chr2:108910810chr2:158622708ENST00000410057712178_207263510.0DomainGS
TgeneACVR1chr2:108910810chr2:158622708ENST00000410057712208_502263510.0DomainProtein kinase
TgeneACVR1chr2:108910810chr2:158622708ENST00000434821611178_207263510.0DomainGS
TgeneACVR1chr2:108910810chr2:158622708ENST00000434821611208_502263510.0DomainProtein kinase
TgeneACVR1chr2:108910810chr2:158622708ENST00000263640611214_222263510.0Nucleotide bindingATP
TgeneACVR1chr2:108910810chr2:158622708ENST00000409283510214_222263510.0Nucleotide bindingATP
TgeneACVR1chr2:108910810chr2:158622708ENST00000410057712214_222263510.0Nucleotide bindingATP
TgeneACVR1chr2:108910810chr2:158622708ENST00000434821611214_222263510.0Nucleotide bindingATP
TgeneACVR1chr2:108910810chr2:158622708ENST00000263640611147_509263510.0Topological domainCytoplasmic
TgeneACVR1chr2:108910810chr2:158622708ENST0000026364061121_123263510.0Topological domainExtracellular
TgeneACVR1chr2:108910810chr2:158622708ENST00000409283510147_509263510.0Topological domainCytoplasmic
TgeneACVR1chr2:108910810chr2:158622708ENST0000040928351021_123263510.0Topological domainExtracellular
TgeneACVR1chr2:108910810chr2:158622708ENST00000410057712147_509263510.0Topological domainCytoplasmic
TgeneACVR1chr2:108910810chr2:158622708ENST0000041005771221_123263510.0Topological domainExtracellular
TgeneACVR1chr2:108910810chr2:158622708ENST00000434821611147_509263510.0Topological domainCytoplasmic
TgeneACVR1chr2:108910810chr2:158622708ENST0000043482161121_123263510.0Topological domainExtracellular
TgeneACVR1chr2:108910810chr2:158622708ENST00000263640611124_146263510.0TransmembraneHelical
TgeneACVR1chr2:108910810chr2:158622708ENST00000409283510124_146263510.0TransmembraneHelical
TgeneACVR1chr2:108910810chr2:158622708ENST00000410057712124_146263510.0TransmembraneHelical
TgeneACVR1chr2:108910810chr2:158622708ENST00000434821611124_146263510.0TransmembraneHelical


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Fusion Gene Sequence for SULT1C2-ACVR1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>88057_88057_1_SULT1C2-ACVR1_SULT1C2_chr2_108910810_ENST00000251481_ACVR1_chr2_158622708_ENST00000263640_length(transcript)=2555nt_BP=730nt
AGCTTCGAGGCCAGTGGGAGGAGGGAGGGGCCAGGCAGCTGAGGGCCAGGAAAGATGTGAAAAACTCTAGCTGGTGACCGAGAGGAGGAG
TAGAGTGTGCCCTTAGTTCATATGAACTAGAGGGAGTTGGTATTTGCACAGCAGTCAGGGTCACATGAGTGATCATGGTACAGTGAGAAG
TTCTCCCTCCCAGGGCCAGGTCACAGGGTTTGTTTCTGTTCAATCCGGATTCTTCCAGTAAAAGCTTCAACTTCCCACACTGAAGCTGAG
AGCCTCCCAAAGTGCTGGCTACCTGCTGAGCGCCCCCGTAACTCTGACACAGTAGTAATTTGAGCCTCTGCAATTGCCGTCTGCTTCCTG
TGAAAGTCCTTTCCGTGCCCACTGACCCTTGAGTGGGCCTTTGAGCTGCTGACTTTCAGCTGGAACTTGAAGGGACCCCAACCCTGAGAC
ACTATGGCCCTGACCTCAGACCTGGGGAAACAGATAAAACTGAAAGAGGTGGAGGGGACCCTCCTGCAGCCTGCAACTGTGGACAACTGG
AGCCAGATCCAGAGCTTCGAGGCCAAACCAGATGATCTCCTCATCTGCACCTACCCTAAAGCAGGGACAACGTGGATTCAGGAAATTGTG
GATATGATTGAACAGAATGGGGACGTGGAGAAGTGCCAGCGAGCCATCATCCAACACCGCCATCCTTTCATTGAGTGGGCTCGGCCACCC
CAACCTTCTGGTTTCATTGCTTCAGACATGACATCAAGACACTCCAGTACCCAGCTGTGGTTAATTACACATTATCATGAAATGGGATCG
TTGTACGACTATCTTCAGCTTACTACTCTGGATACAGTTAGCTGCCTTCGAATAGTGCTGTCCATAGCTAGTGGTCTTGCACATTTGCAC
ATAGAGATATTTGGGACCCAAGGGAAACCAGCCATTGCCCATCGAGATTTAAAGAGCAAAAATATTCTGGTTAAGAAGAATGGACAGTGT
TGCATAGCAGATTTGGGCCTGGCAGTCATGCATTCCCAGAGCACCAATCAGCTTGATGTGGGGAACAATCCCCGTGTGGGCACCAAGCGC
TACATGGCCCCCGAAGTTCTAGATGAAACCATCCAGGTGGATTGTTTCGATTCTTATAAAAGGGTCGATATTTGGGCCTTTGGACTTGTT
TTGTGGGAAGTGGCCAGGCGGATGGTGAGCAATGGTATAGTGGAGGATTACAAGCCACCGTTCTACGATGTGGTTCCCAATGACCCAAGT
TTTGAAGATATGAGGAAGGTAGTCTGTGTGGATCAACAAAGGCCAAACATACCCAACAGATGGTTCTCAGACCCGACATTAACCTCTCTG
GCCAAGCTAATGAAAGAATGCTGGTATCAAAATCCATCCGCAAGACTCACAGCACTGCGTATCAAAAAGACTTTGACCAAAATTGATAAT
TCCCTCGACAAATTGAAAACTGACTGTTGACATTTTCATAGTGTCAAGAAGGAAGATTTGACGTTGTTGTCATTGTCCAGCTGGGACCTA
ATGCTGGCCTGACTGGTTGTCAGAATGGAATCCATCTGTCTCCCTCCCCAAATGGCTGCTTTGACAAGGCAGACGTCGTACCCAGCCATG
TGTTGGGGAGACATCAAAACCACCCTAACCTCGCTCGATGACTGTGAACTGGGCATTTCACGAACTGTTCACACTGCAGAGACTAATGTT
GGACAGACACTGTTGCAAAGGTAGGGACTGGAGGAACACAGAGAAATCCTAAAAGAGATCTGGGCATTAAGTCAGTGGCTTTGCATAGCT
TTCACAAGTCTCCTAGACACTCCCCACGGGAAACTCAAGGAGGTGGTGAATTTTTAATCAGCAATATTGCCTGTGCTTCTCTTCTTTATT
GCACTAGGAATTCTTTGCATTCCTTACTTGCACTGTTACTCTTAATTTTAAAGACCCAACTTGCCAAAATGTTGGCTGCGTACTCCACTG
GTCTGTCTTTGGATAATAGGAATTCAATTTGGCAAAACAAAATGTAATGTCAGACTTTGCTGCATTTTACACATGTGCTGATGTTTACAA
TGATGCCGAACATTAGGAATTGTTTATACACAACTTTGCAAATTATTTATTACTTGTGCACTTAGTAGTTTTTACAAAACTGCTTTGTGC
ATATGTTAAAGCTTATTTTTATGTGGTCTTATGATTTTATTACAGAAATGTTTTTAACACTATACTCTAAAATGGACATTTTCTTTTATT
ATCAGTTAAAATCACATTTTAAGTGCTTCACATTTGTATGTGTGTAGACTGTAACTTTTTTTCAGTTCATATGCAGAACGTATTTAGCCA
TTACCCACGTGACACCACCGAATATATTACTGATTTAGAAGCAAAGATTTCAGTAGAATTTTAGTCCTGAACGCTACGGGGAAAATGCAT
TTTCTTCAGAATTATCCATTACGTGCATTTAAACTCTGCCAGAAAAAAATAACTATTTTGTTTTAATCTACTTTTTGTATTTAGTAGTTA

>88057_88057_1_SULT1C2-ACVR1_SULT1C2_chr2_108910810_ENST00000251481_ACVR1_chr2_158622708_ENST00000263640_length(amino acids)=338AA_BP=92
MALTSDLGKQIKLKEVEGTLLQPATVDNWSQIQSFEAKPDDLLICTYPKAGTTWIQEIVDMIEQNGDVEKCQRAIIQHRHPFIEWARPPQ
PSGFIASDMTSRHSSTQLWLITHYHEMGSLYDYLQLTTLDTVSCLRIVLSIASGLAHLHIEIFGTQGKPAIAHRDLKSKNILVKKNGQCC
IADLGLAVMHSQSTNQLDVGNNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVARRMVSNGIVEDYKPPFYDVVPNDPSF

--------------------------------------------------------------
>88057_88057_2_SULT1C2-ACVR1_SULT1C2_chr2_108910810_ENST00000251481_ACVR1_chr2_158622708_ENST00000409283_length(transcript)=2552nt_BP=730nt
AGCTTCGAGGCCAGTGGGAGGAGGGAGGGGCCAGGCAGCTGAGGGCCAGGAAAGATGTGAAAAACTCTAGCTGGTGACCGAGAGGAGGAG
TAGAGTGTGCCCTTAGTTCATATGAACTAGAGGGAGTTGGTATTTGCACAGCAGTCAGGGTCACATGAGTGATCATGGTACAGTGAGAAG
TTCTCCCTCCCAGGGCCAGGTCACAGGGTTTGTTTCTGTTCAATCCGGATTCTTCCAGTAAAAGCTTCAACTTCCCACACTGAAGCTGAG
AGCCTCCCAAAGTGCTGGCTACCTGCTGAGCGCCCCCGTAACTCTGACACAGTAGTAATTTGAGCCTCTGCAATTGCCGTCTGCTTCCTG
TGAAAGTCCTTTCCGTGCCCACTGACCCTTGAGTGGGCCTTTGAGCTGCTGACTTTCAGCTGGAACTTGAAGGGACCCCAACCCTGAGAC
ACTATGGCCCTGACCTCAGACCTGGGGAAACAGATAAAACTGAAAGAGGTGGAGGGGACCCTCCTGCAGCCTGCAACTGTGGACAACTGG
AGCCAGATCCAGAGCTTCGAGGCCAAACCAGATGATCTCCTCATCTGCACCTACCCTAAAGCAGGGACAACGTGGATTCAGGAAATTGTG
GATATGATTGAACAGAATGGGGACGTGGAGAAGTGCCAGCGAGCCATCATCCAACACCGCCATCCTTTCATTGAGTGGGCTCGGCCACCC
CAACCTTCTGGTTTCATTGCTTCAGACATGACATCAAGACACTCCAGTACCCAGCTGTGGTTAATTACACATTATCATGAAATGGGATCG
TTGTACGACTATCTTCAGCTTACTACTCTGGATACAGTTAGCTGCCTTCGAATAGTGCTGTCCATAGCTAGTGGTCTTGCACATTTGCAC
ATAGAGATATTTGGGACCCAAGGGAAACCAGCCATTGCCCATCGAGATTTAAAGAGCAAAAATATTCTGGTTAAGAAGAATGGACAGTGT
TGCATAGCAGATTTGGGCCTGGCAGTCATGCATTCCCAGAGCACCAATCAGCTTGATGTGGGGAACAATCCCCGTGTGGGCACCAAGCGC
TACATGGCCCCCGAAGTTCTAGATGAAACCATCCAGGTGGATTGTTTCGATTCTTATAAAAGGGTCGATATTTGGGCCTTTGGACTTGTT
TTGTGGGAAGTGGCCAGGCGGATGGTGAGCAATGGTATAGTGGAGGATTACAAGCCACCGTTCTACGATGTGGTTCCCAATGACCCAAGT
TTTGAAGATATGAGGAAGGTAGTCTGTGTGGATCAACAAAGGCCAAACATACCCAACAGATGGTTCTCAGACCCGACATTAACCTCTCTG
GCCAAGCTAATGAAAGAATGCTGGTATCAAAATCCATCCGCAAGACTCACAGCACTGCGTATCAAAAAGACTTTGACCAAAATTGATAAT
TCCCTCGACAAATTGAAAACTGACTGTTGACATTTTCATAGTGTCAAGAAGGAAGATTTGACGTTGTTGTCATTGTCCAGCTGGGACCTA
ATGCTGGCCTGACTGGTTGTCAGAATGGAATCCATCTGTCTCCCTCCCCAAATGGCTGCTTTGACAAGGCAGACGTCGTACCCAGCCATG
TGTTGGGGAGACATCAAAACCACCCTAACCTCGCTCGATGACTGTGAACTGGGCATTTCACGAACTGTTCACACTGCAGAGACTAATGTT
GGACAGACACTGTTGCAAAGGTAGGGACTGGAGGAACACAGAGAAATCCTAAAAGAGATCTGGGCATTAAGTCAGTGGCTTTGCATAGCT
TTCACAAGTCTCCTAGACACTCCCCACGGGAAACTCAAGGAGGTGGTGAATTTTTAATCAGCAATATTGCCTGTGCTTCTCTTCTTTATT
GCACTAGGAATTCTTTGCATTCCTTACTTGCACTGTTACTCTTAATTTTAAAGACCCAACTTGCCAAAATGTTGGCTGCGTACTCCACTG
GTCTGTCTTTGGATAATAGGAATTCAATTTGGCAAAACAAAATGTAATGTCAGACTTTGCTGCATTTTACACATGTGCTGATGTTTACAA
TGATGCCGAACATTAGGAATTGTTTATACACAACTTTGCAAATTATTTATTACTTGTGCACTTAGTAGTTTTTACAAAACTGCTTTGTGC
ATATGTTAAAGCTTATTTTTATGTGGTCTTATGATTTTATTACAGAAATGTTTTTAACACTATACTCTAAAATGGACATTTTCTTTTATT
ATCAGTTAAAATCACATTTTAAGTGCTTCACATTTGTATGTGTGTAGACTGTAACTTTTTTTCAGTTCATATGCAGAACGTATTTAGCCA
TTACCCACGTGACACCACCGAATATATTACTGATTTAGAAGCAAAGATTTCAGTAGAATTTTAGTCCTGAACGCTACGGGGAAAATGCAT
TTTCTTCAGAATTATCCATTACGTGCATTTAAACTCTGCCAGAAAAAAATAACTATTTTGTTTTAATCTACTTTTTGTATTTAGTAGTTA

>88057_88057_2_SULT1C2-ACVR1_SULT1C2_chr2_108910810_ENST00000251481_ACVR1_chr2_158622708_ENST00000409283_length(amino acids)=338AA_BP=92
MALTSDLGKQIKLKEVEGTLLQPATVDNWSQIQSFEAKPDDLLICTYPKAGTTWIQEIVDMIEQNGDVEKCQRAIIQHRHPFIEWARPPQ
PSGFIASDMTSRHSSTQLWLITHYHEMGSLYDYLQLTTLDTVSCLRIVLSIASGLAHLHIEIFGTQGKPAIAHRDLKSKNILVKKNGQCC
IADLGLAVMHSQSTNQLDVGNNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVARRMVSNGIVEDYKPPFYDVVPNDPSF

--------------------------------------------------------------
>88057_88057_3_SULT1C2-ACVR1_SULT1C2_chr2_108910810_ENST00000251481_ACVR1_chr2_158622708_ENST00000410057_length(transcript)=1685nt_BP=730nt
AGCTTCGAGGCCAGTGGGAGGAGGGAGGGGCCAGGCAGCTGAGGGCCAGGAAAGATGTGAAAAACTCTAGCTGGTGACCGAGAGGAGGAG
TAGAGTGTGCCCTTAGTTCATATGAACTAGAGGGAGTTGGTATTTGCACAGCAGTCAGGGTCACATGAGTGATCATGGTACAGTGAGAAG
TTCTCCCTCCCAGGGCCAGGTCACAGGGTTTGTTTCTGTTCAATCCGGATTCTTCCAGTAAAAGCTTCAACTTCCCACACTGAAGCTGAG
AGCCTCCCAAAGTGCTGGCTACCTGCTGAGCGCCCCCGTAACTCTGACACAGTAGTAATTTGAGCCTCTGCAATTGCCGTCTGCTTCCTG
TGAAAGTCCTTTCCGTGCCCACTGACCCTTGAGTGGGCCTTTGAGCTGCTGACTTTCAGCTGGAACTTGAAGGGACCCCAACCCTGAGAC
ACTATGGCCCTGACCTCAGACCTGGGGAAACAGATAAAACTGAAAGAGGTGGAGGGGACCCTCCTGCAGCCTGCAACTGTGGACAACTGG
AGCCAGATCCAGAGCTTCGAGGCCAAACCAGATGATCTCCTCATCTGCACCTACCCTAAAGCAGGGACAACGTGGATTCAGGAAATTGTG
GATATGATTGAACAGAATGGGGACGTGGAGAAGTGCCAGCGAGCCATCATCCAACACCGCCATCCTTTCATTGAGTGGGCTCGGCCACCC
CAACCTTCTGGTTTCATTGCTTCAGACATGACATCAAGACACTCCAGTACCCAGCTGTGGTTAATTACACATTATCATGAAATGGGATCG
TTGTACGACTATCTTCAGCTTACTACTCTGGATACAGTTAGCTGCCTTCGAATAGTGCTGTCCATAGCTAGTGGTCTTGCACATTTGCAC
ATAGAGATATTTGGGACCCAAGGGAAACCAGCCATTGCCCATCGAGATTTAAAGAGCAAAAATATTCTGGTTAAGAAGAATGGACAGTGT
TGCATAGCAGATTTGGGCCTGGCAGTCATGCATTCCCAGAGCACCAATCAGCTTGATGTGGGGAACAATCCCCGTGTGGGCACCAAGCGC
TACATGGCCCCCGAAGTTCTAGATGAAACCATCCAGGTGGATTGTTTCGATTCTTATAAAAGGGTCGATATTTGGGCCTTTGGACTTGTT
TTGTGGGAAGTGGCCAGGCGGATGGTGAGCAATGGTATAGTGGAGGATTACAAGCCACCGTTCTACGATGTGGTTCCCAATGACCCAAGT
TTTGAAGATATGAGGAAGGTAGTCTGTGTGGATCAACAAAGGCCAAACATACCCAACAGATGGTTCTCAGACCCGACATTAACCTCTCTG
GCCAAGCTAATGAAAGAATGCTGGTATCAAAATCCATCCGCAAGACTCACAGCACTGCGTATCAAAAAGACTTTGACCAAAATTGATAAT
TCCCTCGACAAATTGAAAACTGACTGTTGACATTTTCATAGTGTCAAGAAGGAAGATTTGACGTTGTTGTCATTGTCCAGCTGGGACCTA
ATGCTGGCCTGACTGGTTGTCAGAATGGAATCCATCTGTCTCCCTCCCCAAATGGCTGCTTTGACAAGGCAGACGTCGTACCCAGCCATG

>88057_88057_3_SULT1C2-ACVR1_SULT1C2_chr2_108910810_ENST00000251481_ACVR1_chr2_158622708_ENST00000410057_length(amino acids)=338AA_BP=92
MALTSDLGKQIKLKEVEGTLLQPATVDNWSQIQSFEAKPDDLLICTYPKAGTTWIQEIVDMIEQNGDVEKCQRAIIQHRHPFIEWARPPQ
PSGFIASDMTSRHSSTQLWLITHYHEMGSLYDYLQLTTLDTVSCLRIVLSIASGLAHLHIEIFGTQGKPAIAHRDLKSKNILVKKNGQCC
IADLGLAVMHSQSTNQLDVGNNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVARRMVSNGIVEDYKPPFYDVVPNDPSF

--------------------------------------------------------------
>88057_88057_4_SULT1C2-ACVR1_SULT1C2_chr2_108910810_ENST00000251481_ACVR1_chr2_158622708_ENST00000434821_length(transcript)=2552nt_BP=730nt
AGCTTCGAGGCCAGTGGGAGGAGGGAGGGGCCAGGCAGCTGAGGGCCAGGAAAGATGTGAAAAACTCTAGCTGGTGACCGAGAGGAGGAG
TAGAGTGTGCCCTTAGTTCATATGAACTAGAGGGAGTTGGTATTTGCACAGCAGTCAGGGTCACATGAGTGATCATGGTACAGTGAGAAG
TTCTCCCTCCCAGGGCCAGGTCACAGGGTTTGTTTCTGTTCAATCCGGATTCTTCCAGTAAAAGCTTCAACTTCCCACACTGAAGCTGAG
AGCCTCCCAAAGTGCTGGCTACCTGCTGAGCGCCCCCGTAACTCTGACACAGTAGTAATTTGAGCCTCTGCAATTGCCGTCTGCTTCCTG
TGAAAGTCCTTTCCGTGCCCACTGACCCTTGAGTGGGCCTTTGAGCTGCTGACTTTCAGCTGGAACTTGAAGGGACCCCAACCCTGAGAC
ACTATGGCCCTGACCTCAGACCTGGGGAAACAGATAAAACTGAAAGAGGTGGAGGGGACCCTCCTGCAGCCTGCAACTGTGGACAACTGG
AGCCAGATCCAGAGCTTCGAGGCCAAACCAGATGATCTCCTCATCTGCACCTACCCTAAAGCAGGGACAACGTGGATTCAGGAAATTGTG
GATATGATTGAACAGAATGGGGACGTGGAGAAGTGCCAGCGAGCCATCATCCAACACCGCCATCCTTTCATTGAGTGGGCTCGGCCACCC
CAACCTTCTGGTTTCATTGCTTCAGACATGACATCAAGACACTCCAGTACCCAGCTGTGGTTAATTACACATTATCATGAAATGGGATCG
TTGTACGACTATCTTCAGCTTACTACTCTGGATACAGTTAGCTGCCTTCGAATAGTGCTGTCCATAGCTAGTGGTCTTGCACATTTGCAC
ATAGAGATATTTGGGACCCAAGGGAAACCAGCCATTGCCCATCGAGATTTAAAGAGCAAAAATATTCTGGTTAAGAAGAATGGACAGTGT
TGCATAGCAGATTTGGGCCTGGCAGTCATGCATTCCCAGAGCACCAATCAGCTTGATGTGGGGAACAATCCCCGTGTGGGCACCAAGCGC
TACATGGCCCCCGAAGTTCTAGATGAAACCATCCAGGTGGATTGTTTCGATTCTTATAAAAGGGTCGATATTTGGGCCTTTGGACTTGTT
TTGTGGGAAGTGGCCAGGCGGATGGTGAGCAATGGTATAGTGGAGGATTACAAGCCACCGTTCTACGATGTGGTTCCCAATGACCCAAGT
TTTGAAGATATGAGGAAGGTAGTCTGTGTGGATCAACAAAGGCCAAACATACCCAACAGATGGTTCTCAGACCCGACATTAACCTCTCTG
GCCAAGCTAATGAAAGAATGCTGGTATCAAAATCCATCCGCAAGACTCACAGCACTGCGTATCAAAAAGACTTTGACCAAAATTGATAAT
TCCCTCGACAAATTGAAAACTGACTGTTGACATTTTCATAGTGTCAAGAAGGAAGATTTGACGTTGTTGTCATTGTCCAGCTGGGACCTA
ATGCTGGCCTGACTGGTTGTCAGAATGGAATCCATCTGTCTCCCTCCCCAAATGGCTGCTTTGACAAGGCAGACGTCGTACCCAGCCATG
TGTTGGGGAGACATCAAAACCACCCTAACCTCGCTCGATGACTGTGAACTGGGCATTTCACGAACTGTTCACACTGCAGAGACTAATGTT
GGACAGACACTGTTGCAAAGGTAGGGACTGGAGGAACACAGAGAAATCCTAAAAGAGATCTGGGCATTAAGTCAGTGGCTTTGCATAGCT
TTCACAAGTCTCCTAGACACTCCCCACGGGAAACTCAAGGAGGTGGTGAATTTTTAATCAGCAATATTGCCTGTGCTTCTCTTCTTTATT
GCACTAGGAATTCTTTGCATTCCTTACTTGCACTGTTACTCTTAATTTTAAAGACCCAACTTGCCAAAATGTTGGCTGCGTACTCCACTG
GTCTGTCTTTGGATAATAGGAATTCAATTTGGCAAAACAAAATGTAATGTCAGACTTTGCTGCATTTTACACATGTGCTGATGTTTACAA
TGATGCCGAACATTAGGAATTGTTTATACACAACTTTGCAAATTATTTATTACTTGTGCACTTAGTAGTTTTTACAAAACTGCTTTGTGC
ATATGTTAAAGCTTATTTTTATGTGGTCTTATGATTTTATTACAGAAATGTTTTTAACACTATACTCTAAAATGGACATTTTCTTTTATT
ATCAGTTAAAATCACATTTTAAGTGCTTCACATTTGTATGTGTGTAGACTGTAACTTTTTTTCAGTTCATATGCAGAACGTATTTAGCCA
TTACCCACGTGACACCACCGAATATATTACTGATTTAGAAGCAAAGATTTCAGTAGAATTTTAGTCCTGAACGCTACGGGGAAAATGCAT
TTTCTTCAGAATTATCCATTACGTGCATTTAAACTCTGCCAGAAAAAAATAACTATTTTGTTTTAATCTACTTTTTGTATTTAGTAGTTA

>88057_88057_4_SULT1C2-ACVR1_SULT1C2_chr2_108910810_ENST00000251481_ACVR1_chr2_158622708_ENST00000434821_length(amino acids)=338AA_BP=92
MALTSDLGKQIKLKEVEGTLLQPATVDNWSQIQSFEAKPDDLLICTYPKAGTTWIQEIVDMIEQNGDVEKCQRAIIQHRHPFIEWARPPQ
PSGFIASDMTSRHSSTQLWLITHYHEMGSLYDYLQLTTLDTVSCLRIVLSIASGLAHLHIEIFGTQGKPAIAHRDLKSKNILVKKNGQCC
IADLGLAVMHSQSTNQLDVGNNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVARRMVSNGIVEDYKPPFYDVVPNDPSF

--------------------------------------------------------------
>88057_88057_5_SULT1C2-ACVR1_SULT1C2_chr2_108910810_ENST00000326853_ACVR1_chr2_158622708_ENST00000263640_length(transcript)=2555nt_BP=730nt
AGCTTCGAGGCCAGTGGGAGGAGGGAGGGGCCAGGCAGCTGAGGGCCAGGAAAGATGTGAAAAACTCTAGCTGGTGACCGAGAGGAGGAG
TAGAGTGTGCCCTTAGTTCATATGAACTAGAGGGAGTTGGTATTTGCACAGCAGTCAGGGTCACATGAGTGATCATGGTACAGTGAGAAG
TTCTCCCTCCCAGGGCCAGGTCACAGGGTTTGTTTCTGTTCAATCCGGATTCTTCCAGTAAAAGCTTCAACTTCCCACACTGAAGCTGAG
AGCCTCCCAAAGTGCTGGCTACCTGCTGAGCGCCCCCGTAACTCTGACACAGTAGTAATTTGAGCCTCTGCAATTGCCGTCTGCTTCCTG
TGAAAGTCCTTTCCGTGCCCACTGACCCTTGAGTGGGCCTTTGAGCTGCTGACTTTCAGCTGGAACTTGAAGGGACCCCAACCCTGAGAC
ACTATGGCCCTGACCTCAGACCTGGGGAAACAGATAAAACTGAAAGAGGTGGAGGGGACCCTCCTGCAGCCTGCAACTGTGGACAACTGG
AGCCAGATCCAGAGCTTCGAGGCCAAACCAGATGATCTCCTCATCTGCACCTACCCTAAAGCAGGGACAACGTGGATTCAGGAAATTGTG
GATATGATTGAACAGAATGGGGACGTGGAGAAGTGCCAGCGAGCCATCATCCAACACCGCCATCCTTTCATTGAGTGGGCTCGGCCACCC
CAACCTTCTGGTTTCATTGCTTCAGACATGACATCAAGACACTCCAGTACCCAGCTGTGGTTAATTACACATTATCATGAAATGGGATCG
TTGTACGACTATCTTCAGCTTACTACTCTGGATACAGTTAGCTGCCTTCGAATAGTGCTGTCCATAGCTAGTGGTCTTGCACATTTGCAC
ATAGAGATATTTGGGACCCAAGGGAAACCAGCCATTGCCCATCGAGATTTAAAGAGCAAAAATATTCTGGTTAAGAAGAATGGACAGTGT
TGCATAGCAGATTTGGGCCTGGCAGTCATGCATTCCCAGAGCACCAATCAGCTTGATGTGGGGAACAATCCCCGTGTGGGCACCAAGCGC
TACATGGCCCCCGAAGTTCTAGATGAAACCATCCAGGTGGATTGTTTCGATTCTTATAAAAGGGTCGATATTTGGGCCTTTGGACTTGTT
TTGTGGGAAGTGGCCAGGCGGATGGTGAGCAATGGTATAGTGGAGGATTACAAGCCACCGTTCTACGATGTGGTTCCCAATGACCCAAGT
TTTGAAGATATGAGGAAGGTAGTCTGTGTGGATCAACAAAGGCCAAACATACCCAACAGATGGTTCTCAGACCCGACATTAACCTCTCTG
GCCAAGCTAATGAAAGAATGCTGGTATCAAAATCCATCCGCAAGACTCACAGCACTGCGTATCAAAAAGACTTTGACCAAAATTGATAAT
TCCCTCGACAAATTGAAAACTGACTGTTGACATTTTCATAGTGTCAAGAAGGAAGATTTGACGTTGTTGTCATTGTCCAGCTGGGACCTA
ATGCTGGCCTGACTGGTTGTCAGAATGGAATCCATCTGTCTCCCTCCCCAAATGGCTGCTTTGACAAGGCAGACGTCGTACCCAGCCATG
TGTTGGGGAGACATCAAAACCACCCTAACCTCGCTCGATGACTGTGAACTGGGCATTTCACGAACTGTTCACACTGCAGAGACTAATGTT
GGACAGACACTGTTGCAAAGGTAGGGACTGGAGGAACACAGAGAAATCCTAAAAGAGATCTGGGCATTAAGTCAGTGGCTTTGCATAGCT
TTCACAAGTCTCCTAGACACTCCCCACGGGAAACTCAAGGAGGTGGTGAATTTTTAATCAGCAATATTGCCTGTGCTTCTCTTCTTTATT
GCACTAGGAATTCTTTGCATTCCTTACTTGCACTGTTACTCTTAATTTTAAAGACCCAACTTGCCAAAATGTTGGCTGCGTACTCCACTG
GTCTGTCTTTGGATAATAGGAATTCAATTTGGCAAAACAAAATGTAATGTCAGACTTTGCTGCATTTTACACATGTGCTGATGTTTACAA
TGATGCCGAACATTAGGAATTGTTTATACACAACTTTGCAAATTATTTATTACTTGTGCACTTAGTAGTTTTTACAAAACTGCTTTGTGC
ATATGTTAAAGCTTATTTTTATGTGGTCTTATGATTTTATTACAGAAATGTTTTTAACACTATACTCTAAAATGGACATTTTCTTTTATT
ATCAGTTAAAATCACATTTTAAGTGCTTCACATTTGTATGTGTGTAGACTGTAACTTTTTTTCAGTTCATATGCAGAACGTATTTAGCCA
TTACCCACGTGACACCACCGAATATATTACTGATTTAGAAGCAAAGATTTCAGTAGAATTTTAGTCCTGAACGCTACGGGGAAAATGCAT
TTTCTTCAGAATTATCCATTACGTGCATTTAAACTCTGCCAGAAAAAAATAACTATTTTGTTTTAATCTACTTTTTGTATTTAGTAGTTA

>88057_88057_5_SULT1C2-ACVR1_SULT1C2_chr2_108910810_ENST00000326853_ACVR1_chr2_158622708_ENST00000263640_length(amino acids)=338AA_BP=92
MALTSDLGKQIKLKEVEGTLLQPATVDNWSQIQSFEAKPDDLLICTYPKAGTTWIQEIVDMIEQNGDVEKCQRAIIQHRHPFIEWARPPQ
PSGFIASDMTSRHSSTQLWLITHYHEMGSLYDYLQLTTLDTVSCLRIVLSIASGLAHLHIEIFGTQGKPAIAHRDLKSKNILVKKNGQCC
IADLGLAVMHSQSTNQLDVGNNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVARRMVSNGIVEDYKPPFYDVVPNDPSF

--------------------------------------------------------------
>88057_88057_6_SULT1C2-ACVR1_SULT1C2_chr2_108910810_ENST00000326853_ACVR1_chr2_158622708_ENST00000409283_length(transcript)=2552nt_BP=730nt
AGCTTCGAGGCCAGTGGGAGGAGGGAGGGGCCAGGCAGCTGAGGGCCAGGAAAGATGTGAAAAACTCTAGCTGGTGACCGAGAGGAGGAG
TAGAGTGTGCCCTTAGTTCATATGAACTAGAGGGAGTTGGTATTTGCACAGCAGTCAGGGTCACATGAGTGATCATGGTACAGTGAGAAG
TTCTCCCTCCCAGGGCCAGGTCACAGGGTTTGTTTCTGTTCAATCCGGATTCTTCCAGTAAAAGCTTCAACTTCCCACACTGAAGCTGAG
AGCCTCCCAAAGTGCTGGCTACCTGCTGAGCGCCCCCGTAACTCTGACACAGTAGTAATTTGAGCCTCTGCAATTGCCGTCTGCTTCCTG
TGAAAGTCCTTTCCGTGCCCACTGACCCTTGAGTGGGCCTTTGAGCTGCTGACTTTCAGCTGGAACTTGAAGGGACCCCAACCCTGAGAC
ACTATGGCCCTGACCTCAGACCTGGGGAAACAGATAAAACTGAAAGAGGTGGAGGGGACCCTCCTGCAGCCTGCAACTGTGGACAACTGG
AGCCAGATCCAGAGCTTCGAGGCCAAACCAGATGATCTCCTCATCTGCACCTACCCTAAAGCAGGGACAACGTGGATTCAGGAAATTGTG
GATATGATTGAACAGAATGGGGACGTGGAGAAGTGCCAGCGAGCCATCATCCAACACCGCCATCCTTTCATTGAGTGGGCTCGGCCACCC
CAACCTTCTGGTTTCATTGCTTCAGACATGACATCAAGACACTCCAGTACCCAGCTGTGGTTAATTACACATTATCATGAAATGGGATCG
TTGTACGACTATCTTCAGCTTACTACTCTGGATACAGTTAGCTGCCTTCGAATAGTGCTGTCCATAGCTAGTGGTCTTGCACATTTGCAC
ATAGAGATATTTGGGACCCAAGGGAAACCAGCCATTGCCCATCGAGATTTAAAGAGCAAAAATATTCTGGTTAAGAAGAATGGACAGTGT
TGCATAGCAGATTTGGGCCTGGCAGTCATGCATTCCCAGAGCACCAATCAGCTTGATGTGGGGAACAATCCCCGTGTGGGCACCAAGCGC
TACATGGCCCCCGAAGTTCTAGATGAAACCATCCAGGTGGATTGTTTCGATTCTTATAAAAGGGTCGATATTTGGGCCTTTGGACTTGTT
TTGTGGGAAGTGGCCAGGCGGATGGTGAGCAATGGTATAGTGGAGGATTACAAGCCACCGTTCTACGATGTGGTTCCCAATGACCCAAGT
TTTGAAGATATGAGGAAGGTAGTCTGTGTGGATCAACAAAGGCCAAACATACCCAACAGATGGTTCTCAGACCCGACATTAACCTCTCTG
GCCAAGCTAATGAAAGAATGCTGGTATCAAAATCCATCCGCAAGACTCACAGCACTGCGTATCAAAAAGACTTTGACCAAAATTGATAAT
TCCCTCGACAAATTGAAAACTGACTGTTGACATTTTCATAGTGTCAAGAAGGAAGATTTGACGTTGTTGTCATTGTCCAGCTGGGACCTA
ATGCTGGCCTGACTGGTTGTCAGAATGGAATCCATCTGTCTCCCTCCCCAAATGGCTGCTTTGACAAGGCAGACGTCGTACCCAGCCATG
TGTTGGGGAGACATCAAAACCACCCTAACCTCGCTCGATGACTGTGAACTGGGCATTTCACGAACTGTTCACACTGCAGAGACTAATGTT
GGACAGACACTGTTGCAAAGGTAGGGACTGGAGGAACACAGAGAAATCCTAAAAGAGATCTGGGCATTAAGTCAGTGGCTTTGCATAGCT
TTCACAAGTCTCCTAGACACTCCCCACGGGAAACTCAAGGAGGTGGTGAATTTTTAATCAGCAATATTGCCTGTGCTTCTCTTCTTTATT
GCACTAGGAATTCTTTGCATTCCTTACTTGCACTGTTACTCTTAATTTTAAAGACCCAACTTGCCAAAATGTTGGCTGCGTACTCCACTG
GTCTGTCTTTGGATAATAGGAATTCAATTTGGCAAAACAAAATGTAATGTCAGACTTTGCTGCATTTTACACATGTGCTGATGTTTACAA
TGATGCCGAACATTAGGAATTGTTTATACACAACTTTGCAAATTATTTATTACTTGTGCACTTAGTAGTTTTTACAAAACTGCTTTGTGC
ATATGTTAAAGCTTATTTTTATGTGGTCTTATGATTTTATTACAGAAATGTTTTTAACACTATACTCTAAAATGGACATTTTCTTTTATT
ATCAGTTAAAATCACATTTTAAGTGCTTCACATTTGTATGTGTGTAGACTGTAACTTTTTTTCAGTTCATATGCAGAACGTATTTAGCCA
TTACCCACGTGACACCACCGAATATATTACTGATTTAGAAGCAAAGATTTCAGTAGAATTTTAGTCCTGAACGCTACGGGGAAAATGCAT
TTTCTTCAGAATTATCCATTACGTGCATTTAAACTCTGCCAGAAAAAAATAACTATTTTGTTTTAATCTACTTTTTGTATTTAGTAGTTA

>88057_88057_6_SULT1C2-ACVR1_SULT1C2_chr2_108910810_ENST00000326853_ACVR1_chr2_158622708_ENST00000409283_length(amino acids)=338AA_BP=92
MALTSDLGKQIKLKEVEGTLLQPATVDNWSQIQSFEAKPDDLLICTYPKAGTTWIQEIVDMIEQNGDVEKCQRAIIQHRHPFIEWARPPQ
PSGFIASDMTSRHSSTQLWLITHYHEMGSLYDYLQLTTLDTVSCLRIVLSIASGLAHLHIEIFGTQGKPAIAHRDLKSKNILVKKNGQCC
IADLGLAVMHSQSTNQLDVGNNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVARRMVSNGIVEDYKPPFYDVVPNDPSF

--------------------------------------------------------------
>88057_88057_7_SULT1C2-ACVR1_SULT1C2_chr2_108910810_ENST00000326853_ACVR1_chr2_158622708_ENST00000410057_length(transcript)=1685nt_BP=730nt
AGCTTCGAGGCCAGTGGGAGGAGGGAGGGGCCAGGCAGCTGAGGGCCAGGAAAGATGTGAAAAACTCTAGCTGGTGACCGAGAGGAGGAG
TAGAGTGTGCCCTTAGTTCATATGAACTAGAGGGAGTTGGTATTTGCACAGCAGTCAGGGTCACATGAGTGATCATGGTACAGTGAGAAG
TTCTCCCTCCCAGGGCCAGGTCACAGGGTTTGTTTCTGTTCAATCCGGATTCTTCCAGTAAAAGCTTCAACTTCCCACACTGAAGCTGAG
AGCCTCCCAAAGTGCTGGCTACCTGCTGAGCGCCCCCGTAACTCTGACACAGTAGTAATTTGAGCCTCTGCAATTGCCGTCTGCTTCCTG
TGAAAGTCCTTTCCGTGCCCACTGACCCTTGAGTGGGCCTTTGAGCTGCTGACTTTCAGCTGGAACTTGAAGGGACCCCAACCCTGAGAC
ACTATGGCCCTGACCTCAGACCTGGGGAAACAGATAAAACTGAAAGAGGTGGAGGGGACCCTCCTGCAGCCTGCAACTGTGGACAACTGG
AGCCAGATCCAGAGCTTCGAGGCCAAACCAGATGATCTCCTCATCTGCACCTACCCTAAAGCAGGGACAACGTGGATTCAGGAAATTGTG
GATATGATTGAACAGAATGGGGACGTGGAGAAGTGCCAGCGAGCCATCATCCAACACCGCCATCCTTTCATTGAGTGGGCTCGGCCACCC
CAACCTTCTGGTTTCATTGCTTCAGACATGACATCAAGACACTCCAGTACCCAGCTGTGGTTAATTACACATTATCATGAAATGGGATCG
TTGTACGACTATCTTCAGCTTACTACTCTGGATACAGTTAGCTGCCTTCGAATAGTGCTGTCCATAGCTAGTGGTCTTGCACATTTGCAC
ATAGAGATATTTGGGACCCAAGGGAAACCAGCCATTGCCCATCGAGATTTAAAGAGCAAAAATATTCTGGTTAAGAAGAATGGACAGTGT
TGCATAGCAGATTTGGGCCTGGCAGTCATGCATTCCCAGAGCACCAATCAGCTTGATGTGGGGAACAATCCCCGTGTGGGCACCAAGCGC
TACATGGCCCCCGAAGTTCTAGATGAAACCATCCAGGTGGATTGTTTCGATTCTTATAAAAGGGTCGATATTTGGGCCTTTGGACTTGTT
TTGTGGGAAGTGGCCAGGCGGATGGTGAGCAATGGTATAGTGGAGGATTACAAGCCACCGTTCTACGATGTGGTTCCCAATGACCCAAGT
TTTGAAGATATGAGGAAGGTAGTCTGTGTGGATCAACAAAGGCCAAACATACCCAACAGATGGTTCTCAGACCCGACATTAACCTCTCTG
GCCAAGCTAATGAAAGAATGCTGGTATCAAAATCCATCCGCAAGACTCACAGCACTGCGTATCAAAAAGACTTTGACCAAAATTGATAAT
TCCCTCGACAAATTGAAAACTGACTGTTGACATTTTCATAGTGTCAAGAAGGAAGATTTGACGTTGTTGTCATTGTCCAGCTGGGACCTA
ATGCTGGCCTGACTGGTTGTCAGAATGGAATCCATCTGTCTCCCTCCCCAAATGGCTGCTTTGACAAGGCAGACGTCGTACCCAGCCATG

>88057_88057_7_SULT1C2-ACVR1_SULT1C2_chr2_108910810_ENST00000326853_ACVR1_chr2_158622708_ENST00000410057_length(amino acids)=338AA_BP=92
MALTSDLGKQIKLKEVEGTLLQPATVDNWSQIQSFEAKPDDLLICTYPKAGTTWIQEIVDMIEQNGDVEKCQRAIIQHRHPFIEWARPPQ
PSGFIASDMTSRHSSTQLWLITHYHEMGSLYDYLQLTTLDTVSCLRIVLSIASGLAHLHIEIFGTQGKPAIAHRDLKSKNILVKKNGQCC
IADLGLAVMHSQSTNQLDVGNNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVARRMVSNGIVEDYKPPFYDVVPNDPSF

--------------------------------------------------------------
>88057_88057_8_SULT1C2-ACVR1_SULT1C2_chr2_108910810_ENST00000326853_ACVR1_chr2_158622708_ENST00000434821_length(transcript)=2552nt_BP=730nt
AGCTTCGAGGCCAGTGGGAGGAGGGAGGGGCCAGGCAGCTGAGGGCCAGGAAAGATGTGAAAAACTCTAGCTGGTGACCGAGAGGAGGAG
TAGAGTGTGCCCTTAGTTCATATGAACTAGAGGGAGTTGGTATTTGCACAGCAGTCAGGGTCACATGAGTGATCATGGTACAGTGAGAAG
TTCTCCCTCCCAGGGCCAGGTCACAGGGTTTGTTTCTGTTCAATCCGGATTCTTCCAGTAAAAGCTTCAACTTCCCACACTGAAGCTGAG
AGCCTCCCAAAGTGCTGGCTACCTGCTGAGCGCCCCCGTAACTCTGACACAGTAGTAATTTGAGCCTCTGCAATTGCCGTCTGCTTCCTG
TGAAAGTCCTTTCCGTGCCCACTGACCCTTGAGTGGGCCTTTGAGCTGCTGACTTTCAGCTGGAACTTGAAGGGACCCCAACCCTGAGAC
ACTATGGCCCTGACCTCAGACCTGGGGAAACAGATAAAACTGAAAGAGGTGGAGGGGACCCTCCTGCAGCCTGCAACTGTGGACAACTGG
AGCCAGATCCAGAGCTTCGAGGCCAAACCAGATGATCTCCTCATCTGCACCTACCCTAAAGCAGGGACAACGTGGATTCAGGAAATTGTG
GATATGATTGAACAGAATGGGGACGTGGAGAAGTGCCAGCGAGCCATCATCCAACACCGCCATCCTTTCATTGAGTGGGCTCGGCCACCC
CAACCTTCTGGTTTCATTGCTTCAGACATGACATCAAGACACTCCAGTACCCAGCTGTGGTTAATTACACATTATCATGAAATGGGATCG
TTGTACGACTATCTTCAGCTTACTACTCTGGATACAGTTAGCTGCCTTCGAATAGTGCTGTCCATAGCTAGTGGTCTTGCACATTTGCAC
ATAGAGATATTTGGGACCCAAGGGAAACCAGCCATTGCCCATCGAGATTTAAAGAGCAAAAATATTCTGGTTAAGAAGAATGGACAGTGT
TGCATAGCAGATTTGGGCCTGGCAGTCATGCATTCCCAGAGCACCAATCAGCTTGATGTGGGGAACAATCCCCGTGTGGGCACCAAGCGC
TACATGGCCCCCGAAGTTCTAGATGAAACCATCCAGGTGGATTGTTTCGATTCTTATAAAAGGGTCGATATTTGGGCCTTTGGACTTGTT
TTGTGGGAAGTGGCCAGGCGGATGGTGAGCAATGGTATAGTGGAGGATTACAAGCCACCGTTCTACGATGTGGTTCCCAATGACCCAAGT
TTTGAAGATATGAGGAAGGTAGTCTGTGTGGATCAACAAAGGCCAAACATACCCAACAGATGGTTCTCAGACCCGACATTAACCTCTCTG
GCCAAGCTAATGAAAGAATGCTGGTATCAAAATCCATCCGCAAGACTCACAGCACTGCGTATCAAAAAGACTTTGACCAAAATTGATAAT
TCCCTCGACAAATTGAAAACTGACTGTTGACATTTTCATAGTGTCAAGAAGGAAGATTTGACGTTGTTGTCATTGTCCAGCTGGGACCTA
ATGCTGGCCTGACTGGTTGTCAGAATGGAATCCATCTGTCTCCCTCCCCAAATGGCTGCTTTGACAAGGCAGACGTCGTACCCAGCCATG
TGTTGGGGAGACATCAAAACCACCCTAACCTCGCTCGATGACTGTGAACTGGGCATTTCACGAACTGTTCACACTGCAGAGACTAATGTT
GGACAGACACTGTTGCAAAGGTAGGGACTGGAGGAACACAGAGAAATCCTAAAAGAGATCTGGGCATTAAGTCAGTGGCTTTGCATAGCT
TTCACAAGTCTCCTAGACACTCCCCACGGGAAACTCAAGGAGGTGGTGAATTTTTAATCAGCAATATTGCCTGTGCTTCTCTTCTTTATT
GCACTAGGAATTCTTTGCATTCCTTACTTGCACTGTTACTCTTAATTTTAAAGACCCAACTTGCCAAAATGTTGGCTGCGTACTCCACTG
GTCTGTCTTTGGATAATAGGAATTCAATTTGGCAAAACAAAATGTAATGTCAGACTTTGCTGCATTTTACACATGTGCTGATGTTTACAA
TGATGCCGAACATTAGGAATTGTTTATACACAACTTTGCAAATTATTTATTACTTGTGCACTTAGTAGTTTTTACAAAACTGCTTTGTGC
ATATGTTAAAGCTTATTTTTATGTGGTCTTATGATTTTATTACAGAAATGTTTTTAACACTATACTCTAAAATGGACATTTTCTTTTATT
ATCAGTTAAAATCACATTTTAAGTGCTTCACATTTGTATGTGTGTAGACTGTAACTTTTTTTCAGTTCATATGCAGAACGTATTTAGCCA
TTACCCACGTGACACCACCGAATATATTACTGATTTAGAAGCAAAGATTTCAGTAGAATTTTAGTCCTGAACGCTACGGGGAAAATGCAT
TTTCTTCAGAATTATCCATTACGTGCATTTAAACTCTGCCAGAAAAAAATAACTATTTTGTTTTAATCTACTTTTTGTATTTAGTAGTTA

>88057_88057_8_SULT1C2-ACVR1_SULT1C2_chr2_108910810_ENST00000326853_ACVR1_chr2_158622708_ENST00000434821_length(amino acids)=338AA_BP=92
MALTSDLGKQIKLKEVEGTLLQPATVDNWSQIQSFEAKPDDLLICTYPKAGTTWIQEIVDMIEQNGDVEKCQRAIIQHRHPFIEWARPPQ
PSGFIASDMTSRHSSTQLWLITHYHEMGSLYDYLQLTTLDTVSCLRIVLSIASGLAHLHIEIFGTQGKPAIAHRDLKSKNILVKKNGQCC
IADLGLAVMHSQSTNQLDVGNNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVARRMVSNGIVEDYKPPFYDVVPNDPSF

--------------------------------------------------------------
>88057_88057_9_SULT1C2-ACVR1_SULT1C2_chr2_108910810_ENST00000409880_ACVR1_chr2_158622708_ENST00000263640_length(transcript)=2279nt_BP=454nt
CCAAAGTGCTGGCTACCTGCTGAGCGCCCCCGTAACTCTGACACAGTAGTAATTTGAGCCTCTGCAATTGCCGTCTGCTTCCTGTGAAAG
TCCTTTCCGTGCCCACTGACCCTTGAGTGGGCCTTTGAGCTGCTGACTTTCAGCTGGAACTTGAAGGGACCCCAACCCTGAGACACTATG
GCCCTGACCTCAGACCTGGGGAAACAGATAAAACTGAAAGAGGTGGAGGGGACCCTCCTGCAGCCTGCAACTGTGGACAACTGGAGCCAG
ATCCAGAGCTTCGAGGCCAAACCAGATGATCTCCTCATCTGCACCTACCCTAAAGCAGGGACAACGTGGATTCAGGAAATTGTGGATATG
ATTGAACAGAATGGGGACGTGGAGAAGTGCCAGCGAGCCATCATCCAACACCGCCATCCTTTCATTGAGTGGGCTCGGCCACCCCAACCT
TCTGGTTTCATTGCTTCAGACATGACATCAAGACACTCCAGTACCCAGCTGTGGTTAATTACACATTATCATGAAATGGGATCGTTGTAC
GACTATCTTCAGCTTACTACTCTGGATACAGTTAGCTGCCTTCGAATAGTGCTGTCCATAGCTAGTGGTCTTGCACATTTGCACATAGAG
ATATTTGGGACCCAAGGGAAACCAGCCATTGCCCATCGAGATTTAAAGAGCAAAAATATTCTGGTTAAGAAGAATGGACAGTGTTGCATA
GCAGATTTGGGCCTGGCAGTCATGCATTCCCAGAGCACCAATCAGCTTGATGTGGGGAACAATCCCCGTGTGGGCACCAAGCGCTACATG
GCCCCCGAAGTTCTAGATGAAACCATCCAGGTGGATTGTTTCGATTCTTATAAAAGGGTCGATATTTGGGCCTTTGGACTTGTTTTGTGG
GAAGTGGCCAGGCGGATGGTGAGCAATGGTATAGTGGAGGATTACAAGCCACCGTTCTACGATGTGGTTCCCAATGACCCAAGTTTTGAA
GATATGAGGAAGGTAGTCTGTGTGGATCAACAAAGGCCAAACATACCCAACAGATGGTTCTCAGACCCGACATTAACCTCTCTGGCCAAG
CTAATGAAAGAATGCTGGTATCAAAATCCATCCGCAAGACTCACAGCACTGCGTATCAAAAAGACTTTGACCAAAATTGATAATTCCCTC
GACAAATTGAAAACTGACTGTTGACATTTTCATAGTGTCAAGAAGGAAGATTTGACGTTGTTGTCATTGTCCAGCTGGGACCTAATGCTG
GCCTGACTGGTTGTCAGAATGGAATCCATCTGTCTCCCTCCCCAAATGGCTGCTTTGACAAGGCAGACGTCGTACCCAGCCATGTGTTGG
GGAGACATCAAAACCACCCTAACCTCGCTCGATGACTGTGAACTGGGCATTTCACGAACTGTTCACACTGCAGAGACTAATGTTGGACAG
ACACTGTTGCAAAGGTAGGGACTGGAGGAACACAGAGAAATCCTAAAAGAGATCTGGGCATTAAGTCAGTGGCTTTGCATAGCTTTCACA
AGTCTCCTAGACACTCCCCACGGGAAACTCAAGGAGGTGGTGAATTTTTAATCAGCAATATTGCCTGTGCTTCTCTTCTTTATTGCACTA
GGAATTCTTTGCATTCCTTACTTGCACTGTTACTCTTAATTTTAAAGACCCAACTTGCCAAAATGTTGGCTGCGTACTCCACTGGTCTGT
CTTTGGATAATAGGAATTCAATTTGGCAAAACAAAATGTAATGTCAGACTTTGCTGCATTTTACACATGTGCTGATGTTTACAATGATGC
CGAACATTAGGAATTGTTTATACACAACTTTGCAAATTATTTATTACTTGTGCACTTAGTAGTTTTTACAAAACTGCTTTGTGCATATGT
TAAAGCTTATTTTTATGTGGTCTTATGATTTTATTACAGAAATGTTTTTAACACTATACTCTAAAATGGACATTTTCTTTTATTATCAGT
TAAAATCACATTTTAAGTGCTTCACATTTGTATGTGTGTAGACTGTAACTTTTTTTCAGTTCATATGCAGAACGTATTTAGCCATTACCC
ACGTGACACCACCGAATATATTACTGATTTAGAAGCAAAGATTTCAGTAGAATTTTAGTCCTGAACGCTACGGGGAAAATGCATTTTCTT
CAGAATTATCCATTACGTGCATTTAAACTCTGCCAGAAAAAAATAACTATTTTGTTTTAATCTACTTTTTGTATTTAGTAGTTATTTGTA

>88057_88057_9_SULT1C2-ACVR1_SULT1C2_chr2_108910810_ENST00000409880_ACVR1_chr2_158622708_ENST00000263640_length(amino acids)=338AA_BP=92
MALTSDLGKQIKLKEVEGTLLQPATVDNWSQIQSFEAKPDDLLICTYPKAGTTWIQEIVDMIEQNGDVEKCQRAIIQHRHPFIEWARPPQ
PSGFIASDMTSRHSSTQLWLITHYHEMGSLYDYLQLTTLDTVSCLRIVLSIASGLAHLHIEIFGTQGKPAIAHRDLKSKNILVKKNGQCC
IADLGLAVMHSQSTNQLDVGNNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVARRMVSNGIVEDYKPPFYDVVPNDPSF

--------------------------------------------------------------
>88057_88057_10_SULT1C2-ACVR1_SULT1C2_chr2_108910810_ENST00000409880_ACVR1_chr2_158622708_ENST00000409283_length(transcript)=2276nt_BP=454nt
CCAAAGTGCTGGCTACCTGCTGAGCGCCCCCGTAACTCTGACACAGTAGTAATTTGAGCCTCTGCAATTGCCGTCTGCTTCCTGTGAAAG
TCCTTTCCGTGCCCACTGACCCTTGAGTGGGCCTTTGAGCTGCTGACTTTCAGCTGGAACTTGAAGGGACCCCAACCCTGAGACACTATG
GCCCTGACCTCAGACCTGGGGAAACAGATAAAACTGAAAGAGGTGGAGGGGACCCTCCTGCAGCCTGCAACTGTGGACAACTGGAGCCAG
ATCCAGAGCTTCGAGGCCAAACCAGATGATCTCCTCATCTGCACCTACCCTAAAGCAGGGACAACGTGGATTCAGGAAATTGTGGATATG
ATTGAACAGAATGGGGACGTGGAGAAGTGCCAGCGAGCCATCATCCAACACCGCCATCCTTTCATTGAGTGGGCTCGGCCACCCCAACCT
TCTGGTTTCATTGCTTCAGACATGACATCAAGACACTCCAGTACCCAGCTGTGGTTAATTACACATTATCATGAAATGGGATCGTTGTAC
GACTATCTTCAGCTTACTACTCTGGATACAGTTAGCTGCCTTCGAATAGTGCTGTCCATAGCTAGTGGTCTTGCACATTTGCACATAGAG
ATATTTGGGACCCAAGGGAAACCAGCCATTGCCCATCGAGATTTAAAGAGCAAAAATATTCTGGTTAAGAAGAATGGACAGTGTTGCATA
GCAGATTTGGGCCTGGCAGTCATGCATTCCCAGAGCACCAATCAGCTTGATGTGGGGAACAATCCCCGTGTGGGCACCAAGCGCTACATG
GCCCCCGAAGTTCTAGATGAAACCATCCAGGTGGATTGTTTCGATTCTTATAAAAGGGTCGATATTTGGGCCTTTGGACTTGTTTTGTGG
GAAGTGGCCAGGCGGATGGTGAGCAATGGTATAGTGGAGGATTACAAGCCACCGTTCTACGATGTGGTTCCCAATGACCCAAGTTTTGAA
GATATGAGGAAGGTAGTCTGTGTGGATCAACAAAGGCCAAACATACCCAACAGATGGTTCTCAGACCCGACATTAACCTCTCTGGCCAAG
CTAATGAAAGAATGCTGGTATCAAAATCCATCCGCAAGACTCACAGCACTGCGTATCAAAAAGACTTTGACCAAAATTGATAATTCCCTC
GACAAATTGAAAACTGACTGTTGACATTTTCATAGTGTCAAGAAGGAAGATTTGACGTTGTTGTCATTGTCCAGCTGGGACCTAATGCTG
GCCTGACTGGTTGTCAGAATGGAATCCATCTGTCTCCCTCCCCAAATGGCTGCTTTGACAAGGCAGACGTCGTACCCAGCCATGTGTTGG
GGAGACATCAAAACCACCCTAACCTCGCTCGATGACTGTGAACTGGGCATTTCACGAACTGTTCACACTGCAGAGACTAATGTTGGACAG
ACACTGTTGCAAAGGTAGGGACTGGAGGAACACAGAGAAATCCTAAAAGAGATCTGGGCATTAAGTCAGTGGCTTTGCATAGCTTTCACA
AGTCTCCTAGACACTCCCCACGGGAAACTCAAGGAGGTGGTGAATTTTTAATCAGCAATATTGCCTGTGCTTCTCTTCTTTATTGCACTA
GGAATTCTTTGCATTCCTTACTTGCACTGTTACTCTTAATTTTAAAGACCCAACTTGCCAAAATGTTGGCTGCGTACTCCACTGGTCTGT
CTTTGGATAATAGGAATTCAATTTGGCAAAACAAAATGTAATGTCAGACTTTGCTGCATTTTACACATGTGCTGATGTTTACAATGATGC
CGAACATTAGGAATTGTTTATACACAACTTTGCAAATTATTTATTACTTGTGCACTTAGTAGTTTTTACAAAACTGCTTTGTGCATATGT
TAAAGCTTATTTTTATGTGGTCTTATGATTTTATTACAGAAATGTTTTTAACACTATACTCTAAAATGGACATTTTCTTTTATTATCAGT
TAAAATCACATTTTAAGTGCTTCACATTTGTATGTGTGTAGACTGTAACTTTTTTTCAGTTCATATGCAGAACGTATTTAGCCATTACCC
ACGTGACACCACCGAATATATTACTGATTTAGAAGCAAAGATTTCAGTAGAATTTTAGTCCTGAACGCTACGGGGAAAATGCATTTTCTT
CAGAATTATCCATTACGTGCATTTAAACTCTGCCAGAAAAAAATAACTATTTTGTTTTAATCTACTTTTTGTATTTAGTAGTTATTTGTA

>88057_88057_10_SULT1C2-ACVR1_SULT1C2_chr2_108910810_ENST00000409880_ACVR1_chr2_158622708_ENST00000409283_length(amino acids)=338AA_BP=92
MALTSDLGKQIKLKEVEGTLLQPATVDNWSQIQSFEAKPDDLLICTYPKAGTTWIQEIVDMIEQNGDVEKCQRAIIQHRHPFIEWARPPQ
PSGFIASDMTSRHSSTQLWLITHYHEMGSLYDYLQLTTLDTVSCLRIVLSIASGLAHLHIEIFGTQGKPAIAHRDLKSKNILVKKNGQCC
IADLGLAVMHSQSTNQLDVGNNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVARRMVSNGIVEDYKPPFYDVVPNDPSF

--------------------------------------------------------------
>88057_88057_11_SULT1C2-ACVR1_SULT1C2_chr2_108910810_ENST00000409880_ACVR1_chr2_158622708_ENST00000410057_length(transcript)=1409nt_BP=454nt
CCAAAGTGCTGGCTACCTGCTGAGCGCCCCCGTAACTCTGACACAGTAGTAATTTGAGCCTCTGCAATTGCCGTCTGCTTCCTGTGAAAG
TCCTTTCCGTGCCCACTGACCCTTGAGTGGGCCTTTGAGCTGCTGACTTTCAGCTGGAACTTGAAGGGACCCCAACCCTGAGACACTATG
GCCCTGACCTCAGACCTGGGGAAACAGATAAAACTGAAAGAGGTGGAGGGGACCCTCCTGCAGCCTGCAACTGTGGACAACTGGAGCCAG
ATCCAGAGCTTCGAGGCCAAACCAGATGATCTCCTCATCTGCACCTACCCTAAAGCAGGGACAACGTGGATTCAGGAAATTGTGGATATG
ATTGAACAGAATGGGGACGTGGAGAAGTGCCAGCGAGCCATCATCCAACACCGCCATCCTTTCATTGAGTGGGCTCGGCCACCCCAACCT
TCTGGTTTCATTGCTTCAGACATGACATCAAGACACTCCAGTACCCAGCTGTGGTTAATTACACATTATCATGAAATGGGATCGTTGTAC
GACTATCTTCAGCTTACTACTCTGGATACAGTTAGCTGCCTTCGAATAGTGCTGTCCATAGCTAGTGGTCTTGCACATTTGCACATAGAG
ATATTTGGGACCCAAGGGAAACCAGCCATTGCCCATCGAGATTTAAAGAGCAAAAATATTCTGGTTAAGAAGAATGGACAGTGTTGCATA
GCAGATTTGGGCCTGGCAGTCATGCATTCCCAGAGCACCAATCAGCTTGATGTGGGGAACAATCCCCGTGTGGGCACCAAGCGCTACATG
GCCCCCGAAGTTCTAGATGAAACCATCCAGGTGGATTGTTTCGATTCTTATAAAAGGGTCGATATTTGGGCCTTTGGACTTGTTTTGTGG
GAAGTGGCCAGGCGGATGGTGAGCAATGGTATAGTGGAGGATTACAAGCCACCGTTCTACGATGTGGTTCCCAATGACCCAAGTTTTGAA
GATATGAGGAAGGTAGTCTGTGTGGATCAACAAAGGCCAAACATACCCAACAGATGGTTCTCAGACCCGACATTAACCTCTCTGGCCAAG
CTAATGAAAGAATGCTGGTATCAAAATCCATCCGCAAGACTCACAGCACTGCGTATCAAAAAGACTTTGACCAAAATTGATAATTCCCTC
GACAAATTGAAAACTGACTGTTGACATTTTCATAGTGTCAAGAAGGAAGATTTGACGTTGTTGTCATTGTCCAGCTGGGACCTAATGCTG
GCCTGACTGGTTGTCAGAATGGAATCCATCTGTCTCCCTCCCCAAATGGCTGCTTTGACAAGGCAGACGTCGTACCCAGCCATGTGTTGG

>88057_88057_11_SULT1C2-ACVR1_SULT1C2_chr2_108910810_ENST00000409880_ACVR1_chr2_158622708_ENST00000410057_length(amino acids)=338AA_BP=92
MALTSDLGKQIKLKEVEGTLLQPATVDNWSQIQSFEAKPDDLLICTYPKAGTTWIQEIVDMIEQNGDVEKCQRAIIQHRHPFIEWARPPQ
PSGFIASDMTSRHSSTQLWLITHYHEMGSLYDYLQLTTLDTVSCLRIVLSIASGLAHLHIEIFGTQGKPAIAHRDLKSKNILVKKNGQCC
IADLGLAVMHSQSTNQLDVGNNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVARRMVSNGIVEDYKPPFYDVVPNDPSF

--------------------------------------------------------------
>88057_88057_12_SULT1C2-ACVR1_SULT1C2_chr2_108910810_ENST00000409880_ACVR1_chr2_158622708_ENST00000434821_length(transcript)=2276nt_BP=454nt
CCAAAGTGCTGGCTACCTGCTGAGCGCCCCCGTAACTCTGACACAGTAGTAATTTGAGCCTCTGCAATTGCCGTCTGCTTCCTGTGAAAG
TCCTTTCCGTGCCCACTGACCCTTGAGTGGGCCTTTGAGCTGCTGACTTTCAGCTGGAACTTGAAGGGACCCCAACCCTGAGACACTATG
GCCCTGACCTCAGACCTGGGGAAACAGATAAAACTGAAAGAGGTGGAGGGGACCCTCCTGCAGCCTGCAACTGTGGACAACTGGAGCCAG
ATCCAGAGCTTCGAGGCCAAACCAGATGATCTCCTCATCTGCACCTACCCTAAAGCAGGGACAACGTGGATTCAGGAAATTGTGGATATG
ATTGAACAGAATGGGGACGTGGAGAAGTGCCAGCGAGCCATCATCCAACACCGCCATCCTTTCATTGAGTGGGCTCGGCCACCCCAACCT
TCTGGTTTCATTGCTTCAGACATGACATCAAGACACTCCAGTACCCAGCTGTGGTTAATTACACATTATCATGAAATGGGATCGTTGTAC
GACTATCTTCAGCTTACTACTCTGGATACAGTTAGCTGCCTTCGAATAGTGCTGTCCATAGCTAGTGGTCTTGCACATTTGCACATAGAG
ATATTTGGGACCCAAGGGAAACCAGCCATTGCCCATCGAGATTTAAAGAGCAAAAATATTCTGGTTAAGAAGAATGGACAGTGTTGCATA
GCAGATTTGGGCCTGGCAGTCATGCATTCCCAGAGCACCAATCAGCTTGATGTGGGGAACAATCCCCGTGTGGGCACCAAGCGCTACATG
GCCCCCGAAGTTCTAGATGAAACCATCCAGGTGGATTGTTTCGATTCTTATAAAAGGGTCGATATTTGGGCCTTTGGACTTGTTTTGTGG
GAAGTGGCCAGGCGGATGGTGAGCAATGGTATAGTGGAGGATTACAAGCCACCGTTCTACGATGTGGTTCCCAATGACCCAAGTTTTGAA
GATATGAGGAAGGTAGTCTGTGTGGATCAACAAAGGCCAAACATACCCAACAGATGGTTCTCAGACCCGACATTAACCTCTCTGGCCAAG
CTAATGAAAGAATGCTGGTATCAAAATCCATCCGCAAGACTCACAGCACTGCGTATCAAAAAGACTTTGACCAAAATTGATAATTCCCTC
GACAAATTGAAAACTGACTGTTGACATTTTCATAGTGTCAAGAAGGAAGATTTGACGTTGTTGTCATTGTCCAGCTGGGACCTAATGCTG
GCCTGACTGGTTGTCAGAATGGAATCCATCTGTCTCCCTCCCCAAATGGCTGCTTTGACAAGGCAGACGTCGTACCCAGCCATGTGTTGG
GGAGACATCAAAACCACCCTAACCTCGCTCGATGACTGTGAACTGGGCATTTCACGAACTGTTCACACTGCAGAGACTAATGTTGGACAG
ACACTGTTGCAAAGGTAGGGACTGGAGGAACACAGAGAAATCCTAAAAGAGATCTGGGCATTAAGTCAGTGGCTTTGCATAGCTTTCACA
AGTCTCCTAGACACTCCCCACGGGAAACTCAAGGAGGTGGTGAATTTTTAATCAGCAATATTGCCTGTGCTTCTCTTCTTTATTGCACTA
GGAATTCTTTGCATTCCTTACTTGCACTGTTACTCTTAATTTTAAAGACCCAACTTGCCAAAATGTTGGCTGCGTACTCCACTGGTCTGT
CTTTGGATAATAGGAATTCAATTTGGCAAAACAAAATGTAATGTCAGACTTTGCTGCATTTTACACATGTGCTGATGTTTACAATGATGC
CGAACATTAGGAATTGTTTATACACAACTTTGCAAATTATTTATTACTTGTGCACTTAGTAGTTTTTACAAAACTGCTTTGTGCATATGT
TAAAGCTTATTTTTATGTGGTCTTATGATTTTATTACAGAAATGTTTTTAACACTATACTCTAAAATGGACATTTTCTTTTATTATCAGT
TAAAATCACATTTTAAGTGCTTCACATTTGTATGTGTGTAGACTGTAACTTTTTTTCAGTTCATATGCAGAACGTATTTAGCCATTACCC
ACGTGACACCACCGAATATATTACTGATTTAGAAGCAAAGATTTCAGTAGAATTTTAGTCCTGAACGCTACGGGGAAAATGCATTTTCTT
CAGAATTATCCATTACGTGCATTTAAACTCTGCCAGAAAAAAATAACTATTTTGTTTTAATCTACTTTTTGTATTTAGTAGTTATTTGTA

>88057_88057_12_SULT1C2-ACVR1_SULT1C2_chr2_108910810_ENST00000409880_ACVR1_chr2_158622708_ENST00000434821_length(amino acids)=338AA_BP=92
MALTSDLGKQIKLKEVEGTLLQPATVDNWSQIQSFEAKPDDLLICTYPKAGTTWIQEIVDMIEQNGDVEKCQRAIIQHRHPFIEWARPPQ
PSGFIASDMTSRHSSTQLWLITHYHEMGSLYDYLQLTTLDTVSCLRIVLSIASGLAHLHIEIFGTQGKPAIAHRDLKSKNILVKKNGQCC
IADLGLAVMHSQSTNQLDVGNNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVARRMVSNGIVEDYKPPFYDVVPNDPSF

--------------------------------------------------------------
>88057_88057_13_SULT1C2-ACVR1_SULT1C2_chr2_108910810_ENST00000437390_ACVR1_chr2_158622708_ENST00000263640_length(transcript)=2279nt_BP=454nt
CCAAAGTGCTGGCTACCTGCTGAGCGCCCCCGTAACTCTGACACAGTAGTAATTTGAGCCTCTGCAATTGCCGTCTGCTTCCTGTGAAAG
TCCTTTCCGTGCCCACTGACCCTTGAGTGGGCCTTTGAGCTGCTGACTTTCAGCTGGAACTTGAAGGGACCCCAACCCTGAGACACTATG
GCCCTGACCTCAGACCTGGGGAAACAGATAAAACTGAAAGAGGTGGAGGGGACCCTCCTGCAGCCTGCAACTGTGGACAACTGGAGCCAG
ATCCAGAGCTTCGAGGCCAAACCAGATGATCTCCTCATCTGCACCTACCCTAAAGCAGGGACAACGTGGATTCAGGAAATTGTGGATATG
ATTGAACAGAATGGGGACGTGGAGAAGTGCCAGCGAGCCATCATCCAACACCGCCATCCTTTCATTGAGTGGGCTCGGCCACCCCAACCT
TCTGGTTTCATTGCTTCAGACATGACATCAAGACACTCCAGTACCCAGCTGTGGTTAATTACACATTATCATGAAATGGGATCGTTGTAC
GACTATCTTCAGCTTACTACTCTGGATACAGTTAGCTGCCTTCGAATAGTGCTGTCCATAGCTAGTGGTCTTGCACATTTGCACATAGAG
ATATTTGGGACCCAAGGGAAACCAGCCATTGCCCATCGAGATTTAAAGAGCAAAAATATTCTGGTTAAGAAGAATGGACAGTGTTGCATA
GCAGATTTGGGCCTGGCAGTCATGCATTCCCAGAGCACCAATCAGCTTGATGTGGGGAACAATCCCCGTGTGGGCACCAAGCGCTACATG
GCCCCCGAAGTTCTAGATGAAACCATCCAGGTGGATTGTTTCGATTCTTATAAAAGGGTCGATATTTGGGCCTTTGGACTTGTTTTGTGG
GAAGTGGCCAGGCGGATGGTGAGCAATGGTATAGTGGAGGATTACAAGCCACCGTTCTACGATGTGGTTCCCAATGACCCAAGTTTTGAA
GATATGAGGAAGGTAGTCTGTGTGGATCAACAAAGGCCAAACATACCCAACAGATGGTTCTCAGACCCGACATTAACCTCTCTGGCCAAG
CTAATGAAAGAATGCTGGTATCAAAATCCATCCGCAAGACTCACAGCACTGCGTATCAAAAAGACTTTGACCAAAATTGATAATTCCCTC
GACAAATTGAAAACTGACTGTTGACATTTTCATAGTGTCAAGAAGGAAGATTTGACGTTGTTGTCATTGTCCAGCTGGGACCTAATGCTG
GCCTGACTGGTTGTCAGAATGGAATCCATCTGTCTCCCTCCCCAAATGGCTGCTTTGACAAGGCAGACGTCGTACCCAGCCATGTGTTGG
GGAGACATCAAAACCACCCTAACCTCGCTCGATGACTGTGAACTGGGCATTTCACGAACTGTTCACACTGCAGAGACTAATGTTGGACAG
ACACTGTTGCAAAGGTAGGGACTGGAGGAACACAGAGAAATCCTAAAAGAGATCTGGGCATTAAGTCAGTGGCTTTGCATAGCTTTCACA
AGTCTCCTAGACACTCCCCACGGGAAACTCAAGGAGGTGGTGAATTTTTAATCAGCAATATTGCCTGTGCTTCTCTTCTTTATTGCACTA
GGAATTCTTTGCATTCCTTACTTGCACTGTTACTCTTAATTTTAAAGACCCAACTTGCCAAAATGTTGGCTGCGTACTCCACTGGTCTGT
CTTTGGATAATAGGAATTCAATTTGGCAAAACAAAATGTAATGTCAGACTTTGCTGCATTTTACACATGTGCTGATGTTTACAATGATGC
CGAACATTAGGAATTGTTTATACACAACTTTGCAAATTATTTATTACTTGTGCACTTAGTAGTTTTTACAAAACTGCTTTGTGCATATGT
TAAAGCTTATTTTTATGTGGTCTTATGATTTTATTACAGAAATGTTTTTAACACTATACTCTAAAATGGACATTTTCTTTTATTATCAGT
TAAAATCACATTTTAAGTGCTTCACATTTGTATGTGTGTAGACTGTAACTTTTTTTCAGTTCATATGCAGAACGTATTTAGCCATTACCC
ACGTGACACCACCGAATATATTACTGATTTAGAAGCAAAGATTTCAGTAGAATTTTAGTCCTGAACGCTACGGGGAAAATGCATTTTCTT
CAGAATTATCCATTACGTGCATTTAAACTCTGCCAGAAAAAAATAACTATTTTGTTTTAATCTACTTTTTGTATTTAGTAGTTATTTGTA

>88057_88057_13_SULT1C2-ACVR1_SULT1C2_chr2_108910810_ENST00000437390_ACVR1_chr2_158622708_ENST00000263640_length(amino acids)=338AA_BP=92
MALTSDLGKQIKLKEVEGTLLQPATVDNWSQIQSFEAKPDDLLICTYPKAGTTWIQEIVDMIEQNGDVEKCQRAIIQHRHPFIEWARPPQ
PSGFIASDMTSRHSSTQLWLITHYHEMGSLYDYLQLTTLDTVSCLRIVLSIASGLAHLHIEIFGTQGKPAIAHRDLKSKNILVKKNGQCC
IADLGLAVMHSQSTNQLDVGNNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVARRMVSNGIVEDYKPPFYDVVPNDPSF

--------------------------------------------------------------
>88057_88057_14_SULT1C2-ACVR1_SULT1C2_chr2_108910810_ENST00000437390_ACVR1_chr2_158622708_ENST00000409283_length(transcript)=2276nt_BP=454nt
CCAAAGTGCTGGCTACCTGCTGAGCGCCCCCGTAACTCTGACACAGTAGTAATTTGAGCCTCTGCAATTGCCGTCTGCTTCCTGTGAAAG
TCCTTTCCGTGCCCACTGACCCTTGAGTGGGCCTTTGAGCTGCTGACTTTCAGCTGGAACTTGAAGGGACCCCAACCCTGAGACACTATG
GCCCTGACCTCAGACCTGGGGAAACAGATAAAACTGAAAGAGGTGGAGGGGACCCTCCTGCAGCCTGCAACTGTGGACAACTGGAGCCAG
ATCCAGAGCTTCGAGGCCAAACCAGATGATCTCCTCATCTGCACCTACCCTAAAGCAGGGACAACGTGGATTCAGGAAATTGTGGATATG
ATTGAACAGAATGGGGACGTGGAGAAGTGCCAGCGAGCCATCATCCAACACCGCCATCCTTTCATTGAGTGGGCTCGGCCACCCCAACCT
TCTGGTTTCATTGCTTCAGACATGACATCAAGACACTCCAGTACCCAGCTGTGGTTAATTACACATTATCATGAAATGGGATCGTTGTAC
GACTATCTTCAGCTTACTACTCTGGATACAGTTAGCTGCCTTCGAATAGTGCTGTCCATAGCTAGTGGTCTTGCACATTTGCACATAGAG
ATATTTGGGACCCAAGGGAAACCAGCCATTGCCCATCGAGATTTAAAGAGCAAAAATATTCTGGTTAAGAAGAATGGACAGTGTTGCATA
GCAGATTTGGGCCTGGCAGTCATGCATTCCCAGAGCACCAATCAGCTTGATGTGGGGAACAATCCCCGTGTGGGCACCAAGCGCTACATG
GCCCCCGAAGTTCTAGATGAAACCATCCAGGTGGATTGTTTCGATTCTTATAAAAGGGTCGATATTTGGGCCTTTGGACTTGTTTTGTGG
GAAGTGGCCAGGCGGATGGTGAGCAATGGTATAGTGGAGGATTACAAGCCACCGTTCTACGATGTGGTTCCCAATGACCCAAGTTTTGAA
GATATGAGGAAGGTAGTCTGTGTGGATCAACAAAGGCCAAACATACCCAACAGATGGTTCTCAGACCCGACATTAACCTCTCTGGCCAAG
CTAATGAAAGAATGCTGGTATCAAAATCCATCCGCAAGACTCACAGCACTGCGTATCAAAAAGACTTTGACCAAAATTGATAATTCCCTC
GACAAATTGAAAACTGACTGTTGACATTTTCATAGTGTCAAGAAGGAAGATTTGACGTTGTTGTCATTGTCCAGCTGGGACCTAATGCTG
GCCTGACTGGTTGTCAGAATGGAATCCATCTGTCTCCCTCCCCAAATGGCTGCTTTGACAAGGCAGACGTCGTACCCAGCCATGTGTTGG
GGAGACATCAAAACCACCCTAACCTCGCTCGATGACTGTGAACTGGGCATTTCACGAACTGTTCACACTGCAGAGACTAATGTTGGACAG
ACACTGTTGCAAAGGTAGGGACTGGAGGAACACAGAGAAATCCTAAAAGAGATCTGGGCATTAAGTCAGTGGCTTTGCATAGCTTTCACA
AGTCTCCTAGACACTCCCCACGGGAAACTCAAGGAGGTGGTGAATTTTTAATCAGCAATATTGCCTGTGCTTCTCTTCTTTATTGCACTA
GGAATTCTTTGCATTCCTTACTTGCACTGTTACTCTTAATTTTAAAGACCCAACTTGCCAAAATGTTGGCTGCGTACTCCACTGGTCTGT
CTTTGGATAATAGGAATTCAATTTGGCAAAACAAAATGTAATGTCAGACTTTGCTGCATTTTACACATGTGCTGATGTTTACAATGATGC
CGAACATTAGGAATTGTTTATACACAACTTTGCAAATTATTTATTACTTGTGCACTTAGTAGTTTTTACAAAACTGCTTTGTGCATATGT
TAAAGCTTATTTTTATGTGGTCTTATGATTTTATTACAGAAATGTTTTTAACACTATACTCTAAAATGGACATTTTCTTTTATTATCAGT
TAAAATCACATTTTAAGTGCTTCACATTTGTATGTGTGTAGACTGTAACTTTTTTTCAGTTCATATGCAGAACGTATTTAGCCATTACCC
ACGTGACACCACCGAATATATTACTGATTTAGAAGCAAAGATTTCAGTAGAATTTTAGTCCTGAACGCTACGGGGAAAATGCATTTTCTT
CAGAATTATCCATTACGTGCATTTAAACTCTGCCAGAAAAAAATAACTATTTTGTTTTAATCTACTTTTTGTATTTAGTAGTTATTTGTA

>88057_88057_14_SULT1C2-ACVR1_SULT1C2_chr2_108910810_ENST00000437390_ACVR1_chr2_158622708_ENST00000409283_length(amino acids)=338AA_BP=92
MALTSDLGKQIKLKEVEGTLLQPATVDNWSQIQSFEAKPDDLLICTYPKAGTTWIQEIVDMIEQNGDVEKCQRAIIQHRHPFIEWARPPQ
PSGFIASDMTSRHSSTQLWLITHYHEMGSLYDYLQLTTLDTVSCLRIVLSIASGLAHLHIEIFGTQGKPAIAHRDLKSKNILVKKNGQCC
IADLGLAVMHSQSTNQLDVGNNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVARRMVSNGIVEDYKPPFYDVVPNDPSF

--------------------------------------------------------------
>88057_88057_15_SULT1C2-ACVR1_SULT1C2_chr2_108910810_ENST00000437390_ACVR1_chr2_158622708_ENST00000410057_length(transcript)=1409nt_BP=454nt
CCAAAGTGCTGGCTACCTGCTGAGCGCCCCCGTAACTCTGACACAGTAGTAATTTGAGCCTCTGCAATTGCCGTCTGCTTCCTGTGAAAG
TCCTTTCCGTGCCCACTGACCCTTGAGTGGGCCTTTGAGCTGCTGACTTTCAGCTGGAACTTGAAGGGACCCCAACCCTGAGACACTATG
GCCCTGACCTCAGACCTGGGGAAACAGATAAAACTGAAAGAGGTGGAGGGGACCCTCCTGCAGCCTGCAACTGTGGACAACTGGAGCCAG
ATCCAGAGCTTCGAGGCCAAACCAGATGATCTCCTCATCTGCACCTACCCTAAAGCAGGGACAACGTGGATTCAGGAAATTGTGGATATG
ATTGAACAGAATGGGGACGTGGAGAAGTGCCAGCGAGCCATCATCCAACACCGCCATCCTTTCATTGAGTGGGCTCGGCCACCCCAACCT
TCTGGTTTCATTGCTTCAGACATGACATCAAGACACTCCAGTACCCAGCTGTGGTTAATTACACATTATCATGAAATGGGATCGTTGTAC
GACTATCTTCAGCTTACTACTCTGGATACAGTTAGCTGCCTTCGAATAGTGCTGTCCATAGCTAGTGGTCTTGCACATTTGCACATAGAG
ATATTTGGGACCCAAGGGAAACCAGCCATTGCCCATCGAGATTTAAAGAGCAAAAATATTCTGGTTAAGAAGAATGGACAGTGTTGCATA
GCAGATTTGGGCCTGGCAGTCATGCATTCCCAGAGCACCAATCAGCTTGATGTGGGGAACAATCCCCGTGTGGGCACCAAGCGCTACATG
GCCCCCGAAGTTCTAGATGAAACCATCCAGGTGGATTGTTTCGATTCTTATAAAAGGGTCGATATTTGGGCCTTTGGACTTGTTTTGTGG
GAAGTGGCCAGGCGGATGGTGAGCAATGGTATAGTGGAGGATTACAAGCCACCGTTCTACGATGTGGTTCCCAATGACCCAAGTTTTGAA
GATATGAGGAAGGTAGTCTGTGTGGATCAACAAAGGCCAAACATACCCAACAGATGGTTCTCAGACCCGACATTAACCTCTCTGGCCAAG
CTAATGAAAGAATGCTGGTATCAAAATCCATCCGCAAGACTCACAGCACTGCGTATCAAAAAGACTTTGACCAAAATTGATAATTCCCTC
GACAAATTGAAAACTGACTGTTGACATTTTCATAGTGTCAAGAAGGAAGATTTGACGTTGTTGTCATTGTCCAGCTGGGACCTAATGCTG
GCCTGACTGGTTGTCAGAATGGAATCCATCTGTCTCCCTCCCCAAATGGCTGCTTTGACAAGGCAGACGTCGTACCCAGCCATGTGTTGG

>88057_88057_15_SULT1C2-ACVR1_SULT1C2_chr2_108910810_ENST00000437390_ACVR1_chr2_158622708_ENST00000410057_length(amino acids)=338AA_BP=92
MALTSDLGKQIKLKEVEGTLLQPATVDNWSQIQSFEAKPDDLLICTYPKAGTTWIQEIVDMIEQNGDVEKCQRAIIQHRHPFIEWARPPQ
PSGFIASDMTSRHSSTQLWLITHYHEMGSLYDYLQLTTLDTVSCLRIVLSIASGLAHLHIEIFGTQGKPAIAHRDLKSKNILVKKNGQCC
IADLGLAVMHSQSTNQLDVGNNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVARRMVSNGIVEDYKPPFYDVVPNDPSF

--------------------------------------------------------------
>88057_88057_16_SULT1C2-ACVR1_SULT1C2_chr2_108910810_ENST00000437390_ACVR1_chr2_158622708_ENST00000434821_length(transcript)=2276nt_BP=454nt
CCAAAGTGCTGGCTACCTGCTGAGCGCCCCCGTAACTCTGACACAGTAGTAATTTGAGCCTCTGCAATTGCCGTCTGCTTCCTGTGAAAG
TCCTTTCCGTGCCCACTGACCCTTGAGTGGGCCTTTGAGCTGCTGACTTTCAGCTGGAACTTGAAGGGACCCCAACCCTGAGACACTATG
GCCCTGACCTCAGACCTGGGGAAACAGATAAAACTGAAAGAGGTGGAGGGGACCCTCCTGCAGCCTGCAACTGTGGACAACTGGAGCCAG
ATCCAGAGCTTCGAGGCCAAACCAGATGATCTCCTCATCTGCACCTACCCTAAAGCAGGGACAACGTGGATTCAGGAAATTGTGGATATG
ATTGAACAGAATGGGGACGTGGAGAAGTGCCAGCGAGCCATCATCCAACACCGCCATCCTTTCATTGAGTGGGCTCGGCCACCCCAACCT
TCTGGTTTCATTGCTTCAGACATGACATCAAGACACTCCAGTACCCAGCTGTGGTTAATTACACATTATCATGAAATGGGATCGTTGTAC
GACTATCTTCAGCTTACTACTCTGGATACAGTTAGCTGCCTTCGAATAGTGCTGTCCATAGCTAGTGGTCTTGCACATTTGCACATAGAG
ATATTTGGGACCCAAGGGAAACCAGCCATTGCCCATCGAGATTTAAAGAGCAAAAATATTCTGGTTAAGAAGAATGGACAGTGTTGCATA
GCAGATTTGGGCCTGGCAGTCATGCATTCCCAGAGCACCAATCAGCTTGATGTGGGGAACAATCCCCGTGTGGGCACCAAGCGCTACATG
GCCCCCGAAGTTCTAGATGAAACCATCCAGGTGGATTGTTTCGATTCTTATAAAAGGGTCGATATTTGGGCCTTTGGACTTGTTTTGTGG
GAAGTGGCCAGGCGGATGGTGAGCAATGGTATAGTGGAGGATTACAAGCCACCGTTCTACGATGTGGTTCCCAATGACCCAAGTTTTGAA
GATATGAGGAAGGTAGTCTGTGTGGATCAACAAAGGCCAAACATACCCAACAGATGGTTCTCAGACCCGACATTAACCTCTCTGGCCAAG
CTAATGAAAGAATGCTGGTATCAAAATCCATCCGCAAGACTCACAGCACTGCGTATCAAAAAGACTTTGACCAAAATTGATAATTCCCTC
GACAAATTGAAAACTGACTGTTGACATTTTCATAGTGTCAAGAAGGAAGATTTGACGTTGTTGTCATTGTCCAGCTGGGACCTAATGCTG
GCCTGACTGGTTGTCAGAATGGAATCCATCTGTCTCCCTCCCCAAATGGCTGCTTTGACAAGGCAGACGTCGTACCCAGCCATGTGTTGG
GGAGACATCAAAACCACCCTAACCTCGCTCGATGACTGTGAACTGGGCATTTCACGAACTGTTCACACTGCAGAGACTAATGTTGGACAG
ACACTGTTGCAAAGGTAGGGACTGGAGGAACACAGAGAAATCCTAAAAGAGATCTGGGCATTAAGTCAGTGGCTTTGCATAGCTTTCACA
AGTCTCCTAGACACTCCCCACGGGAAACTCAAGGAGGTGGTGAATTTTTAATCAGCAATATTGCCTGTGCTTCTCTTCTTTATTGCACTA
GGAATTCTTTGCATTCCTTACTTGCACTGTTACTCTTAATTTTAAAGACCCAACTTGCCAAAATGTTGGCTGCGTACTCCACTGGTCTGT
CTTTGGATAATAGGAATTCAATTTGGCAAAACAAAATGTAATGTCAGACTTTGCTGCATTTTACACATGTGCTGATGTTTACAATGATGC
CGAACATTAGGAATTGTTTATACACAACTTTGCAAATTATTTATTACTTGTGCACTTAGTAGTTTTTACAAAACTGCTTTGTGCATATGT
TAAAGCTTATTTTTATGTGGTCTTATGATTTTATTACAGAAATGTTTTTAACACTATACTCTAAAATGGACATTTTCTTTTATTATCAGT
TAAAATCACATTTTAAGTGCTTCACATTTGTATGTGTGTAGACTGTAACTTTTTTTCAGTTCATATGCAGAACGTATTTAGCCATTACCC
ACGTGACACCACCGAATATATTACTGATTTAGAAGCAAAGATTTCAGTAGAATTTTAGTCCTGAACGCTACGGGGAAAATGCATTTTCTT
CAGAATTATCCATTACGTGCATTTAAACTCTGCCAGAAAAAAATAACTATTTTGTTTTAATCTACTTTTTGTATTTAGTAGTTATTTGTA

>88057_88057_16_SULT1C2-ACVR1_SULT1C2_chr2_108910810_ENST00000437390_ACVR1_chr2_158622708_ENST00000434821_length(amino acids)=338AA_BP=92
MALTSDLGKQIKLKEVEGTLLQPATVDNWSQIQSFEAKPDDLLICTYPKAGTTWIQEIVDMIEQNGDVEKCQRAIIQHRHPFIEWARPPQ
PSGFIASDMTSRHSSTQLWLITHYHEMGSLYDYLQLTTLDTVSCLRIVLSIASGLAHLHIEIFGTQGKPAIAHRDLKSKNILVKKNGQCC
IADLGLAVMHSQSTNQLDVGNNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVARRMVSNGIVEDYKPPFYDVVPNDPSF

--------------------------------------------------------------

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Fusion Gene PPI Analysis for SULT1C2-ACVR1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for SULT1C2-ACVR1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for SULT1C2-ACVR1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneC0016037Fibrodysplasia Ossificans Progressiva5CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
TgeneC0017638Glioma3CGI;CTD_human
TgeneC0259783mixed gliomas3CTD_human
TgeneC0555198Malignant Glioma3CTD_human
TgeneC0004114Astrocytoma1CTD_human
TgeneC0006142Malignant neoplasm of breast1CTD_human
TgeneC0085576Iron-Refractory Iron Deficiency Anemia1GENOMICS_ENGLAND
TgeneC0205768Subependymal Giant Cell Astrocytoma1CTD_human
TgeneC0242488Acute Lung Injury1CTD_human
TgeneC0280783Juvenile Pilocytic Astrocytoma1CTD_human
TgeneC0280785Diffuse Astrocytoma1CTD_human
TgeneC0334579Anaplastic astrocytoma1CTD_human
TgeneC0334580Protoplasmic astrocytoma1CTD_human
TgeneC0334581Gemistocytic astrocytoma1CTD_human
TgeneC0334582Fibrillary Astrocytoma1CTD_human
TgeneC0334583Pilocytic Astrocytoma1CTD_human
TgeneC0338070Childhood Cerebral Astrocytoma1CTD_human
TgeneC0547065Mixed oligoastrocytoma1CTD_human
TgeneC0678222Breast Carcinoma1CTD_human
TgeneC0750935Cerebral Astrocytoma1CTD_human
TgeneC0750936Intracranial Astrocytoma1CTD_human
TgeneC1257931Mammary Neoplasms, Human1CTD_human
TgeneC1458155Mammary Neoplasms1CTD_human
TgeneC1704230Grade I Astrocytoma1CTD_human
TgeneC4704874Mammary Carcinoma, Human1CTD_human