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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:TIAL1-PRMT2 (FusionGDB2 ID:HG7073TG3275)

Fusion Gene Summary for TIAL1-PRMT2

check button Fusion gene summary
Fusion gene informationFusion gene name: TIAL1-PRMT2
Fusion gene ID: hg7073tg3275
HgeneTgene
Gene symbol

TIAL1

PRMT2

Gene ID

7073

3275

Gene nameTIA1 cytotoxic granule associated RNA binding protein like 1protein arginine methyltransferase 2
SynonymsTCBP|TIARHRMT1L1
Cytomap('TIAL1')('PRMT2')

10q26.11

21q22.3

Type of geneprotein-codingprotein-coding
Descriptionnucleolysin TIART-cluster binding proteinTIA-1-related nucleolysinTIA1 relatedaging-associated gene 7 proteinprotein arginine N-methyltransferase 2HMT1 (hnRNP methyltransferase, S. cerevisiae)-like 1HMT1 hnRNP methyltransferase-like 1PRMT2 alphaPRMT2 betaPRMT2 gammahistone-arginine N-methyltransferase PRMT2
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000369093, ENST00000436547, 
ENST00000369092, ENST00000463089, 
Fusion gene scores* DoF score9 X 9 X 5=4059 X 8 X 4=288
# samples 99
** MAII scorelog2(9/405*10)=-2.16992500144231
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(9/288*10)=-1.67807190511264
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: TIAL1 [Title/Abstract] AND PRMT2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointTIAL1(121347663)-PRMT2(48068369), # samples:1
Anticipated loss of major functional domain due to fusion event.TIAL1-PRMT2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
TIAL1-PRMT2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
TIAL1-PRMT2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
TIAL1-PRMT2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgenePRMT2

GO:0016571

histone methylation

19405910

TgenePRMT2

GO:0032088

negative regulation of NF-kappaB transcription factor activity

16648481

TgenePRMT2

GO:0045892

negative regulation of transcription, DNA-templated

16648481

TgenePRMT2

GO:0045893

positive regulation of transcription, DNA-templated

12039952

TgenePRMT2

GO:0060765

regulation of androgen receptor signaling pathway

17587566


check buttonFusion gene breakpoints across TIAL1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across PRMT2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4OVTCGA-09-1666TIAL1chr10

121347663

-PRMT2chr21

48068369

+


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Fusion Gene ORF analysis for TIAL1-PRMT2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000369093ENST00000491389TIAL1chr10

121347663

-PRMT2chr21

48068369

+
5CDS-3UTRENST00000436547ENST00000491389TIAL1chr10

121347663

-PRMT2chr21

48068369

+
5UTR-3CDSENST00000369092ENST00000291705TIAL1chr10

121347663

-PRMT2chr21

48068369

+
5UTR-3CDSENST00000369092ENST00000334494TIAL1chr10

121347663

-PRMT2chr21

48068369

+
5UTR-3CDSENST00000369092ENST00000355680TIAL1chr10

121347663

-PRMT2chr21

48068369

+
5UTR-3CDSENST00000369092ENST00000397628TIAL1chr10

121347663

-PRMT2chr21

48068369

+
5UTR-3CDSENST00000369092ENST00000397637TIAL1chr10

121347663

-PRMT2chr21

48068369

+
5UTR-3CDSENST00000369092ENST00000397638TIAL1chr10

121347663

-PRMT2chr21

48068369

+
5UTR-3CDSENST00000369092ENST00000440086TIAL1chr10

121347663

-PRMT2chr21

48068369

+
5UTR-3CDSENST00000369092ENST00000451211TIAL1chr10

121347663

-PRMT2chr21

48068369

+
5UTR-3CDSENST00000369092ENST00000458387TIAL1chr10

121347663

-PRMT2chr21

48068369

+
5UTR-3UTRENST00000369092ENST00000491389TIAL1chr10

121347663

-PRMT2chr21

48068369

+
In-frameENST00000369093ENST00000291705TIAL1chr10

121347663

-PRMT2chr21

48068369

+
In-frameENST00000369093ENST00000334494TIAL1chr10

121347663

-PRMT2chr21

48068369

+
In-frameENST00000369093ENST00000355680TIAL1chr10

121347663

-PRMT2chr21

48068369

+
In-frameENST00000369093ENST00000397628TIAL1chr10

121347663

-PRMT2chr21

48068369

+
In-frameENST00000369093ENST00000397637TIAL1chr10

121347663

-PRMT2chr21

48068369

+
In-frameENST00000369093ENST00000397638TIAL1chr10

121347663

-PRMT2chr21

48068369

+
In-frameENST00000369093ENST00000440086TIAL1chr10

121347663

-PRMT2chr21

48068369

+
In-frameENST00000369093ENST00000451211TIAL1chr10

121347663

-PRMT2chr21

48068369

+
In-frameENST00000369093ENST00000458387TIAL1chr10

121347663

-PRMT2chr21

48068369

+
In-frameENST00000436547ENST00000291705TIAL1chr10

121347663

-PRMT2chr21

48068369

+
In-frameENST00000436547ENST00000334494TIAL1chr10

121347663

-PRMT2chr21

48068369

+
In-frameENST00000436547ENST00000355680TIAL1chr10

121347663

-PRMT2chr21

48068369

+
In-frameENST00000436547ENST00000397628TIAL1chr10

121347663

-PRMT2chr21

48068369

+
In-frameENST00000436547ENST00000397637TIAL1chr10

121347663

-PRMT2chr21

48068369

+
In-frameENST00000436547ENST00000397638TIAL1chr10

121347663

-PRMT2chr21

48068369

+
In-frameENST00000436547ENST00000440086TIAL1chr10

121347663

-PRMT2chr21

48068369

+
In-frameENST00000436547ENST00000451211TIAL1chr10

121347663

-PRMT2chr21

48068369

+
In-frameENST00000436547ENST00000458387TIAL1chr10

121347663

-PRMT2chr21

48068369

+
intron-3CDSENST00000463089ENST00000291705TIAL1chr10

121347663

-PRMT2chr21

48068369

+
intron-3CDSENST00000463089ENST00000334494TIAL1chr10

121347663

-PRMT2chr21

48068369

+
intron-3CDSENST00000463089ENST00000355680TIAL1chr10

121347663

-PRMT2chr21

48068369

+
intron-3CDSENST00000463089ENST00000397628TIAL1chr10

121347663

-PRMT2chr21

48068369

+
intron-3CDSENST00000463089ENST00000397637TIAL1chr10

121347663

-PRMT2chr21

48068369

+
intron-3CDSENST00000463089ENST00000397638TIAL1chr10

121347663

-PRMT2chr21

48068369

+
intron-3CDSENST00000463089ENST00000440086TIAL1chr10

121347663

-PRMT2chr21

48068369

+
intron-3CDSENST00000463089ENST00000451211TIAL1chr10

121347663

-PRMT2chr21

48068369

+
intron-3CDSENST00000463089ENST00000458387TIAL1chr10

121347663

-PRMT2chr21

48068369

+
intron-3UTRENST00000463089ENST00000491389TIAL1chr10

121347663

-PRMT2chr21

48068369

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000369093TIAL1chr10121347663-ENST00000355680PRMT2chr2148068369+175815901133377
ENST00000369093TIAL1chr10121347663-ENST00000397638PRMT2chr2148068369+175815901133377
ENST00000369093TIAL1chr10121347663-ENST00000291705PRMT2chr2148068369+113715976760235
ENST00000369093TIAL1chr10121347663-ENST00000458387PRMT2chr2148068369+13091590737245
ENST00000369093TIAL1chr10121347663-ENST00000451211PRMT2chr2148068369+13131590701233
ENST00000369093TIAL1chr10121347663-ENST00000397637PRMT2chr2148068369+175815901133377
ENST00000369093TIAL1chr10121347663-ENST00000334494PRMT2chr2148068369+9991590686228
ENST00000369093TIAL1chr10121347663-ENST00000397628PRMT2chr2148068369+6401590593197
ENST00000369093TIAL1chr10121347663-ENST00000440086PRMT2chr2148068369+16251590827275
ENST00000436547TIAL1chr10121347663-ENST00000355680PRMT2chr2148068369+177317431148381
ENST00000436547TIAL1chr10121347663-ENST00000397638PRMT2chr2148068369+177317431148381
ENST00000436547TIAL1chr10121347663-ENST00000291705PRMT2chr2148068369+115217478275235
ENST00000436547TIAL1chr10121347663-ENST00000458387PRMT2chr2148068369+13241743752249
ENST00000436547TIAL1chr10121347663-ENST00000451211PRMT2chr2148068369+13281743716237
ENST00000436547TIAL1chr10121347663-ENST00000397637PRMT2chr2148068369+177317431148381
ENST00000436547TIAL1chr10121347663-ENST00000334494PRMT2chr2148068369+10141743701232
ENST00000436547TIAL1chr10121347663-ENST00000397628PRMT2chr2148068369+6551743608201
ENST00000436547TIAL1chr10121347663-ENST00000440086PRMT2chr2148068369+16401743842279

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000369093ENST00000355680TIAL1chr10121347663-PRMT2chr2148068369+0.009148310.9908517
ENST00000369093ENST00000397638TIAL1chr10121347663-PRMT2chr2148068369+0.009148310.9908517
ENST00000369093ENST00000291705TIAL1chr10121347663-PRMT2chr2148068369+0.0072965790.99270344
ENST00000369093ENST00000458387TIAL1chr10121347663-PRMT2chr2148068369+0.0077814130.9922186
ENST00000369093ENST00000451211TIAL1chr10121347663-PRMT2chr2148068369+0.0028343130.9971656
ENST00000369093ENST00000397637TIAL1chr10121347663-PRMT2chr2148068369+0.009148310.9908517
ENST00000369093ENST00000334494TIAL1chr10121347663-PRMT2chr2148068369+0.044547340.9554527
ENST00000369093ENST00000397628TIAL1chr10121347663-PRMT2chr2148068369+0.0073493880.99265057
ENST00000369093ENST00000440086TIAL1chr10121347663-PRMT2chr2148068369+0.0053016490.9946984
ENST00000436547ENST00000355680TIAL1chr10121347663-PRMT2chr2148068369+0.0091851720.99081486
ENST00000436547ENST00000397638TIAL1chr10121347663-PRMT2chr2148068369+0.0091851720.99081486
ENST00000436547ENST00000291705TIAL1chr10121347663-PRMT2chr2148068369+0.0058611590.99413884
ENST00000436547ENST00000458387TIAL1chr10121347663-PRMT2chr2148068369+0.0074243340.99257565
ENST00000436547ENST00000451211TIAL1chr10121347663-PRMT2chr2148068369+0.0025097680.9974903
ENST00000436547ENST00000397637TIAL1chr10121347663-PRMT2chr2148068369+0.0091851720.99081486
ENST00000436547ENST00000334494TIAL1chr10121347663-PRMT2chr2148068369+0.044773690.9552263
ENST00000436547ENST00000397628TIAL1chr10121347663-PRMT2chr2148068369+0.0078752380.99212474
ENST00000436547ENST00000440086TIAL1chr10121347663-PRMT2chr2148068369+0.0054221690.9945779

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Fusion Genomic Features for TIAL1-PRMT2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
TIAL1chr10121347663-PRMT2chr2148068369+1.12E-060.9999989
TIAL1chr10121347663-PRMT2chr2148068369+1.12E-060.9999989

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for TIAL1-PRMT2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr10:121347663/chr21:48068369)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTIAL1chr10:121347663chr21:48068369ENST00000369093-212205_27743393.0DomainRRM 3
HgeneTIAL1chr10:121347663chr21:48068369ENST00000369093-21297_17543393.0DomainRRM 2
HgeneTIAL1chr10:121347663chr21:48068369ENST00000369093-2129_8543393.0DomainRRM 1
HgeneTIAL1chr10:121347663chr21:48068369ENST00000436547-212205_27743376.0DomainRRM 3
HgeneTIAL1chr10:121347663chr21:48068369ENST00000436547-21297_17543376.0DomainRRM 2
HgeneTIAL1chr10:121347663chr21:48068369ENST00000436547-2129_8543376.0DomainRRM 1
TgenePRMT2chr10:121347663chr21:48068369ENST000003344943730_89109285.0DomainSH3
TgenePRMT2chr10:121347663chr21:48068369ENST000003344943799_432109285.0DomainSAM-dependent MTase PRMT-type
TgenePRMT2chr10:121347663chr21:48068369ENST0000035568041230_89109434.0DomainSH3
TgenePRMT2chr10:121347663chr21:48068369ENST0000035568041299_432109434.0DomainSAM-dependent MTase PRMT-type
TgenePRMT2chr10:121347663chr21:48068369ENST0000039763731130_89109434.0DomainSH3
TgenePRMT2chr10:121347663chr21:48068369ENST0000039763731199_432109434.0DomainSAM-dependent MTase PRMT-type
TgenePRMT2chr10:121347663chr21:48068369ENST0000039763831130_89109434.0DomainSH3
TgenePRMT2chr10:121347663chr21:48068369ENST0000039763831199_432109434.0DomainSAM-dependent MTase PRMT-type
TgenePRMT2chr10:121347663chr21:48068369ENST000004400863930_89109332.0DomainSH3
TgenePRMT2chr10:121347663chr21:48068369ENST000004400863999_432109332.0DomainSAM-dependent MTase PRMT-type


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Fusion Gene Sequence for TIAL1-PRMT2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>90834_90834_1_TIAL1-PRMT2_TIAL1_chr10_121347663_ENST00000369093_PRMT2_chr21_48068369_ENST00000291705_length(transcript)=1137nt_BP=159nt
TTGTCCCGGGATCGCTCCGTCGCACCCACCATGATGGAAGACGACGGGCAGCCCCGGACTCTATACGTAGGTAACCTTTCCAGAGATGTG
ACAGAAGTCCTTATACTTCAGTTGTTCAGTCAGATTGGACCCTGTAAAAGCTGTAAAATGATAACAGAGAAACTCCACTTGGAGATGTTG
GCAGACCAGCCACGAACAACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGT
GGGACTGGGATCATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGTGTACGCGGTGGAGGCCAGTGAGATGGCACAGCACACG
GGGCAGCTGGTCCTGCAGAACGGCTTTGCTGACATCATCACCGTGTACCAGCAGAAGGTGGAGGATGTGGTGCTGCCCGAGAAGGTGGAC
GTGCTGGTGTCTGAGTGGATGGGGACCTGCCTGCTGGTTGGAGAAAAAGTCTTCCCCATCTGGAGATGACAGTTGATGCTTTATTTGGAA
AGCAGTGTGCATATCTTGAGGGGTGATGAACACAAGCAAACCAAGTTGCACCTGGCTTCTGCACACTCCTGCGAAAGTCGGTGAACATTC
ACTCCACATTGACCCCTCCCTAGCCTGGCAGGTGACGTCAGGGTCCTTCACAGACAAACACGCTTGGGCTCGGCAGGAGCTGCCGTGGCC
ACCCCCGCTGCCCAGTGTCTGCCCTCTAGAAGTAGGCTGTGTTTCCAGGTGTTCACCCGTGGTGCCCACAGTGCCGACCCGTGGCTGGGT
CGGAGCTCCATGTTCCTAAGCTAGGTCTAGGTCTACACTCCTAGGACGCACGCATATCAGCCCGTGTACCCTGTGACAGTGACTGTCCCC
ACCTCCTATGTTAGTGGTGCCCTTACTGCCGTCGCTCATCCACTCGTGTGGGACGTAGGATTGCACAGGGCTGTGCCAGTGGCGTGTAGG
GAACACTGCCCTGGCTCAGCGTGCGAGCTAAGGTGGTGATGTATGCGATGGGACTCTGCATGGGATAGTACAGTTGTGTAGACGTCTTCC
AAATAAATTATGTGTTGGTCCATCGCACATGCTCAATAAATATTTTTAAATGAGTGA

>90834_90834_1_TIAL1-PRMT2_TIAL1_chr10_121347663_ENST00000369093_PRMT2_chr21_48068369_ENST00000291705_length(amino acids)=235AA_BP=1
METQPTSRGQTLGSGGGHGSSCRAQACLSVKDPDVTCQAREGSMWSECSPTFAGVCRSQVQLGLLVFITPQDMHTAFQIKHQLSSPDGED
FFSNQQAGPHPLRHQHVHLLGQHHILHLLLVHGDDVSKAVLQDQLPRVLCHLTGLHRVHRSRPRIVCTEETDDPSPTAHVQDDFIRQGFF
ILQDDTVVFSCSWLVCQHLQVEFLCYHFTAFTGSNLTEQLKYKDFCHISGKVTYV

--------------------------------------------------------------
>90834_90834_2_TIAL1-PRMT2_TIAL1_chr10_121347663_ENST00000369093_PRMT2_chr21_48068369_ENST00000334494_length(transcript)=999nt_BP=159nt
TTGTCCCGGGATCGCTCCGTCGCACCCACCATGATGGAAGACGACGGGCAGCCCCGGACTCTATACGTAGGTAACCTTTCCAGAGATGTG
ACAGAAGTCCTTATACTTCAGTTGTTCAGTCAGATTGGACCCTGTAAAAGCTGTAAAATGATAACAGAGAAACTCCACTTGGAGATGTTG
GCAGACCAGCCACGAACAACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGT
GGGACTGGGATCATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGTGTACGCGGTGGAGGCCAGTGAGATGGCACAGCACACG
GGGCAGCTGGTCCTGCAGAACGGCTTTGCTGACATCATCACCGTGTACCAGCAGAAGGTGGAGGATGTGGTGCTGCCCGAGAAGGTGGAC
GTGCTGGTGTCTGAGTGGATGGGGACCTGCCTGCTGGCTGCGCCTCTCCTGAGCTGCCGCATTCTCCCCTGCACCTGTGCGTCTGGCCCT
CTTCACGTCCTCCTGGCCTGCTGTCTGCCTCTCCCCTGCACCTGTGCGTCTGTCCCTCTTCATGTCCTCCTTGCCTGCTGTCTGCCTGTT
CTCAGAGCCCCTCAGCCCTCAGGCCTTCATCTCTCCTGGCCCATCTTCCTACTCTGACGCTGACATGTAGTAAAAGTCTGAAGACAGAGA
AGAGTGCATGTGCGTTTAGCATAGGAGGGGCAGCTTTCAGTCAGTGCAGCAAGGGCATGTAGTTGTTCAGAGATGGTGCTGGAACGACTG
ATTTGGAGAAAAGAGGCCCTTCTTCACACCATCTGCTAAAATAAACCTCAGATGGGCTCAAGAGTTAAATATTTAAGAAAAGGAGGAAAC
AAAAAAATTGCTACAAGTTTATTTGTTGTTAGGATGGGAAAGGTTTTTCTAAGAACCAAGTTCATAATGAAGCTGTCAAATAAAATACTT
GACAAAAAA

>90834_90834_2_TIAL1-PRMT2_TIAL1_chr10_121347663_ENST00000369093_PRMT2_chr21_48068369_ENST00000334494_length(amino acids)=228AA_BP=53
LSRDRSVAPTMMEDDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDVGC
GTGIISLFCAHYARPRAVYAVEASEMAQHTGQLVLQNGFADIITVYQQKVEDVVLPEKVDVLVSEWMGTCLLAAPLLSCRILPCTCASGP
LHVLLACCLPLPCTCASVPLHVLLACCLPVLRAPQPSGLHLSWPIFLL

--------------------------------------------------------------
>90834_90834_3_TIAL1-PRMT2_TIAL1_chr10_121347663_ENST00000369093_PRMT2_chr21_48068369_ENST00000355680_length(transcript)=1758nt_BP=159nt
TTGTCCCGGGATCGCTCCGTCGCACCCACCATGATGGAAGACGACGGGCAGCCCCGGACTCTATACGTAGGTAACCTTTCCAGAGATGTG
ACAGAAGTCCTTATACTTCAGTTGTTCAGTCAGATTGGACCCTGTAAAAGCTGTAAAATGATAACAGAGAAACTCCACTTGGAGATGTTG
GCAGACCAGCCACGAACAACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGT
GGGACTGGGATCATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGTGTACGCGGTGGAGGCCAGTGAGATGGCACAGCACACG
GGGCAGCTGGTCCTGCAGAACGGCTTTGCTGACATCATCACCGTGTACCAGCAGAAGGTGGAGGATGTGGTGCTGCCCGAGAAGGTGGAC
GTGCTGGTGTCTGAGTGGATGGGGACCTGCCTGCTGTTTGAGTTCATGATCGAGTCCATCCTGTATGCCCGGGATGCCTGGCTGAAGGAG
GACGGGGTCATTTGGCCCACCATGGCTGCGTTGCACCTTGTGCCCTGCAGTGCTGATAAGGATTATCGTAGCAAGGTGCTCTTCTGGGAC
AACGCGTACGAGTTCAACCTCAGCGCTCTGAAATCTTTAGCAGTTAAGGAGTTTTTTTCAAAGCCCAAGTATAACCACATTTTGAAACCA
GAAGACTGTCTCTCTGAACCGTGCACTATATTGCAGTTGGACATGAGAACCGTGCAAATTTCTGATCTAGAGACCCTGAGGGGCGAGCTG
CGCTTCGACATCAGGAAGGCGGGGACCCTGCACGGCTTCACGGCCTGGTTTAGCGTCCACTTCCAGAGCCTGCAGGAGGGGCAGCCGCCG
CAGGTGCTCAGCACCGGGCCCTTCCACCCCACCACACACTGGAAGCAGACGCTGTTCATGATGGACGACCCAGTCCCTGTCCATACAGGA
GACGTGGTCACGGGTTCAGTTGTGTTGCAGAGAAACCCAGTGTGGAGAAGGCACATGTCTGTGGCTCTGAGCTGGGCTGTCACTTCCAGA
CAAGACCCCACATCTCAAAAAGTTGGAGAAAAAGTCTTCCCCATCTGGAGATGACAGTTGATGCTTTATTTGGAAAGCAGTGTGCATATC
TTGAGGGGTGATGAACACAAGCAAACCAAGTTGCACCTGGCTTCTGCACACTCCTGCGAAAGTCGGTGAACATTCACTCCACATTGACCC
CTCCCTAGCCTGGCAGGTGACGTCAGGGTCCTTCACAGACAAACACGCTTGGGCTCGGCAGGAGCTGCCGTGGCCACCCCCGCTGCCCAG
TGTCTGCCCTCTAGAAGTAGGCTGTGTTTCCAGGTGTTCACCCGTGGTGCCCACAGTGCCGACCCGTGGCTGGGTCGGAGCTCCATGTTC
CTAAGCTAGGTCTAGGTCTACACTCCTAGGACGCACGCATATCAGCCCGTGTACCCTGTGACAGTGACTGTCCCCACCTCCTATGTTAGT
GGTGCCCTTACTGCCGTCGCTCATCCACTCGTGTGGGACGTAGGATTGCACAGGGCTGTGCCAGTGGCGTGTAGGGAACACTGCCCTGGC
TCAGCGTGCGAGCTAAGGTGGTGATGTATGCGATGGGACTCTGCATGGGATAGTACAGTTGTGTAGACGTCTTCCAAATAAATTATGTGT
TGGTCCATCGCACATGCTCAATAAATATTTTTAAATGAGTGAATGTCA

>90834_90834_3_TIAL1-PRMT2_TIAL1_chr10_121347663_ENST00000369093_PRMT2_chr21_48068369_ENST00000355680_length(amino acids)=377AA_BP=53
LSRDRSVAPTMMEDDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDVGC
GTGIISLFCAHYARPRAVYAVEASEMAQHTGQLVLQNGFADIITVYQQKVEDVVLPEKVDVLVSEWMGTCLLFEFMIESILYARDAWLKE
DGVIWPTMAALHLVPCSADKDYRSKVLFWDNAYEFNLSALKSLAVKEFFSKPKYNHILKPEDCLSEPCTILQLDMRTVQISDLETLRGEL
RFDIRKAGTLHGFTAWFSVHFQSLQEGQPPQVLSTGPFHPTTHWKQTLFMMDDPVPVHTGDVVTGSVVLQRNPVWRRHMSVALSWAVTSR
QDPTSQKVGEKVFPIWR

--------------------------------------------------------------
>90834_90834_4_TIAL1-PRMT2_TIAL1_chr10_121347663_ENST00000369093_PRMT2_chr21_48068369_ENST00000397628_length(transcript)=640nt_BP=159nt
TTGTCCCGGGATCGCTCCGTCGCACCCACCATGATGGAAGACGACGGGCAGCCCCGGACTCTATACGTAGGTAACCTTTCCAGAGATGTG
ACAGAAGTCCTTATACTTCAGTTGTTCAGTCAGATTGGACCCTGTAAAAGCTGTAAAATGATAACAGAGAAACTCCACTTGGAGATGTTG
GCAGACCAGCCACGAACAACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGT
GGGACTGGGATCATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGTGTACGCGGTGGAGGCCAGTGAGATGGCACAGCACACG
GGGCAGCTGGTCCTGCAGAACGGCTTTGCTGACATCATCACCGTGTACCAGCAGAAGGTGGAGGATGTGGTGCTGCCCGAGAAGGTGGAC
GTGCTGGTGTCTGAGTGGATGGGGACCTGCCTGCTGGTGAGGGCGGGCGTGCGGGCAGCTGGGGGCCGGAGCTGGGGGGCTTCTGAGCAC
GGGCTCGGCTGGGCCAACCTCAGGATCTCAAGGGTCGTGCGTGATTCATTTTGATGTTTTCCCTAATGTGAGGTCTAATTAATTTCTTGT
GTGGACATTG

>90834_90834_4_TIAL1-PRMT2_TIAL1_chr10_121347663_ENST00000369093_PRMT2_chr21_48068369_ENST00000397628_length(amino acids)=197AA_BP=53
LSRDRSVAPTMMEDDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDVGC
GTGIISLFCAHYARPRAVYAVEASEMAQHTGQLVLQNGFADIITVYQQKVEDVVLPEKVDVLVSEWMGTCLLVRAGVRAAGGRSWGASEH
GLGWANLRISRVVRDSF

--------------------------------------------------------------
>90834_90834_5_TIAL1-PRMT2_TIAL1_chr10_121347663_ENST00000369093_PRMT2_chr21_48068369_ENST00000397637_length(transcript)=1758nt_BP=159nt
TTGTCCCGGGATCGCTCCGTCGCACCCACCATGATGGAAGACGACGGGCAGCCCCGGACTCTATACGTAGGTAACCTTTCCAGAGATGTG
ACAGAAGTCCTTATACTTCAGTTGTTCAGTCAGATTGGACCCTGTAAAAGCTGTAAAATGATAACAGAGAAACTCCACTTGGAGATGTTG
GCAGACCAGCCACGAACAACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGT
GGGACTGGGATCATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGTGTACGCGGTGGAGGCCAGTGAGATGGCACAGCACACG
GGGCAGCTGGTCCTGCAGAACGGCTTTGCTGACATCATCACCGTGTACCAGCAGAAGGTGGAGGATGTGGTGCTGCCCGAGAAGGTGGAC
GTGCTGGTGTCTGAGTGGATGGGGACCTGCCTGCTGTTTGAGTTCATGATCGAGTCCATCCTGTATGCCCGGGATGCCTGGCTGAAGGAG
GACGGGGTCATTTGGCCCACCATGGCTGCGTTGCACCTTGTGCCCTGCAGTGCTGATAAGGATTATCGTAGCAAGGTGCTCTTCTGGGAC
AACGCGTACGAGTTCAACCTCAGCGCTCTGAAATCTTTAGCAGTTAAGGAGTTTTTTTCAAAGCCCAAGTATAACCACATTTTGAAACCA
GAAGACTGTCTCTCTGAACCGTGCACTATATTGCAGTTGGACATGAGAACCGTGCAAATTTCTGATCTAGAGACCCTGAGGGGCGAGCTG
CGCTTCGACATCAGGAAGGCGGGGACCCTGCACGGCTTCACGGCCTGGTTTAGCGTCCACTTCCAGAGCCTGCAGGAGGGGCAGCCGCCG
CAGGTGCTCAGCACCGGGCCCTTCCACCCCACCACACACTGGAAGCAGACGCTGTTCATGATGGACGACCCAGTCCCTGTCCATACAGGA
GACGTGGTCACGGGTTCAGTTGTGTTGCAGAGAAACCCAGTGTGGAGAAGGCACATGTCTGTGGCTCTGAGCTGGGCTGTCACTTCCAGA
CAAGACCCCACATCTCAAAAAGTTGGAGAAAAAGTCTTCCCCATCTGGAGATGACAGTTGATGCTTTATTTGGAAAGCAGTGTGCATATC
TTGAGGGGTGATGAACACAAGCAAACCAAGTTGCACCTGGCTTCTGCACACTCCTGCGAAAGTCGGTGAACATTCACTCCACATTGACCC
CTCCCTAGCCTGGCAGGTGACGTCAGGGTCCTTCACAGACAAACACGCTTGGGCTCGGCAGGAGCTGCCGTGGCCACCCCCGCTGCCCAG
TGTCTGCCCTCTAGAAGTAGGCTGTGTTTCCAGGTGTTCACCCGTGGTGCCCACAGTGCCGACCCGTGGCTGGGTCGGAGCTCCATGTTC
CTAAGCTAGGTCTAGGTCTACACTCCTAGGACGCACGCATATCAGCCCGTGTACCCTGTGACAGTGACTGTCCCCACCTCCTATGTTAGT
GGTGCCCTTACTGCCGTCGCTCATCCACTCGTGTGGGACGTAGGATTGCACAGGGCTGTGCCAGTGGCGTGTAGGGAACACTGCCCTGGC
TCAGCGTGCGAGCTAAGGTGGTGATGTATGCGATGGGACTCTGCATGGGATAGTACAGTTGTGTAGACGTCTTCCAAATAAATTATGTGT
TGGTCCATCGCACATGCTCAATAAATATTTTTAAATGAGTGAATGTCA

>90834_90834_5_TIAL1-PRMT2_TIAL1_chr10_121347663_ENST00000369093_PRMT2_chr21_48068369_ENST00000397637_length(amino acids)=377AA_BP=53
LSRDRSVAPTMMEDDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDVGC
GTGIISLFCAHYARPRAVYAVEASEMAQHTGQLVLQNGFADIITVYQQKVEDVVLPEKVDVLVSEWMGTCLLFEFMIESILYARDAWLKE
DGVIWPTMAALHLVPCSADKDYRSKVLFWDNAYEFNLSALKSLAVKEFFSKPKYNHILKPEDCLSEPCTILQLDMRTVQISDLETLRGEL
RFDIRKAGTLHGFTAWFSVHFQSLQEGQPPQVLSTGPFHPTTHWKQTLFMMDDPVPVHTGDVVTGSVVLQRNPVWRRHMSVALSWAVTSR
QDPTSQKVGEKVFPIWR

--------------------------------------------------------------
>90834_90834_6_TIAL1-PRMT2_TIAL1_chr10_121347663_ENST00000369093_PRMT2_chr21_48068369_ENST00000397638_length(transcript)=1758nt_BP=159nt
TTGTCCCGGGATCGCTCCGTCGCACCCACCATGATGGAAGACGACGGGCAGCCCCGGACTCTATACGTAGGTAACCTTTCCAGAGATGTG
ACAGAAGTCCTTATACTTCAGTTGTTCAGTCAGATTGGACCCTGTAAAAGCTGTAAAATGATAACAGAGAAACTCCACTTGGAGATGTTG
GCAGACCAGCCACGAACAACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGT
GGGACTGGGATCATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGTGTACGCGGTGGAGGCCAGTGAGATGGCACAGCACACG
GGGCAGCTGGTCCTGCAGAACGGCTTTGCTGACATCATCACCGTGTACCAGCAGAAGGTGGAGGATGTGGTGCTGCCCGAGAAGGTGGAC
GTGCTGGTGTCTGAGTGGATGGGGACCTGCCTGCTGTTTGAGTTCATGATCGAGTCCATCCTGTATGCCCGGGATGCCTGGCTGAAGGAG
GACGGGGTCATTTGGCCCACCATGGCTGCGTTGCACCTTGTGCCCTGCAGTGCTGATAAGGATTATCGTAGCAAGGTGCTCTTCTGGGAC
AACGCGTACGAGTTCAACCTCAGCGCTCTGAAATCTTTAGCAGTTAAGGAGTTTTTTTCAAAGCCCAAGTATAACCACATTTTGAAACCA
GAAGACTGTCTCTCTGAACCGTGCACTATATTGCAGTTGGACATGAGAACCGTGCAAATTTCTGATCTAGAGACCCTGAGGGGCGAGCTG
CGCTTCGACATCAGGAAGGCGGGGACCCTGCACGGCTTCACGGCCTGGTTTAGCGTCCACTTCCAGAGCCTGCAGGAGGGGCAGCCGCCG
CAGGTGCTCAGCACCGGGCCCTTCCACCCCACCACACACTGGAAGCAGACGCTGTTCATGATGGACGACCCAGTCCCTGTCCATACAGGA
GACGTGGTCACGGGTTCAGTTGTGTTGCAGAGAAACCCAGTGTGGAGAAGGCACATGTCTGTGGCTCTGAGCTGGGCTGTCACTTCCAGA
CAAGACCCCACATCTCAAAAAGTTGGAGAAAAAGTCTTCCCCATCTGGAGATGACAGTTGATGCTTTATTTGGAAAGCAGTGTGCATATC
TTGAGGGGTGATGAACACAAGCAAACCAAGTTGCACCTGGCTTCTGCACACTCCTGCGAAAGTCGGTGAACATTCACTCCACATTGACCC
CTCCCTAGCCTGGCAGGTGACGTCAGGGTCCTTCACAGACAAACACGCTTGGGCTCGGCAGGAGCTGCCGTGGCCACCCCCGCTGCCCAG
TGTCTGCCCTCTAGAAGTAGGCTGTGTTTCCAGGTGTTCACCCGTGGTGCCCACAGTGCCGACCCGTGGCTGGGTCGGAGCTCCATGTTC
CTAAGCTAGGTCTAGGTCTACACTCCTAGGACGCACGCATATCAGCCCGTGTACCCTGTGACAGTGACTGTCCCCACCTCCTATGTTAGT
GGTGCCCTTACTGCCGTCGCTCATCCACTCGTGTGGGACGTAGGATTGCACAGGGCTGTGCCAGTGGCGTGTAGGGAACACTGCCCTGGC
TCAGCGTGCGAGCTAAGGTGGTGATGTATGCGATGGGACTCTGCATGGGATAGTACAGTTGTGTAGACGTCTTCCAAATAAATTATGTGT
TGGTCCATCGCACATGCTCAATAAATATTTTTAAATGAGTGAATGTCA

>90834_90834_6_TIAL1-PRMT2_TIAL1_chr10_121347663_ENST00000369093_PRMT2_chr21_48068369_ENST00000397638_length(amino acids)=377AA_BP=53
LSRDRSVAPTMMEDDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDVGC
GTGIISLFCAHYARPRAVYAVEASEMAQHTGQLVLQNGFADIITVYQQKVEDVVLPEKVDVLVSEWMGTCLLFEFMIESILYARDAWLKE
DGVIWPTMAALHLVPCSADKDYRSKVLFWDNAYEFNLSALKSLAVKEFFSKPKYNHILKPEDCLSEPCTILQLDMRTVQISDLETLRGEL
RFDIRKAGTLHGFTAWFSVHFQSLQEGQPPQVLSTGPFHPTTHWKQTLFMMDDPVPVHTGDVVTGSVVLQRNPVWRRHMSVALSWAVTSR
QDPTSQKVGEKVFPIWR

--------------------------------------------------------------
>90834_90834_7_TIAL1-PRMT2_TIAL1_chr10_121347663_ENST00000369093_PRMT2_chr21_48068369_ENST00000440086_length(transcript)=1625nt_BP=159nt
TTGTCCCGGGATCGCTCCGTCGCACCCACCATGATGGAAGACGACGGGCAGCCCCGGACTCTATACGTAGGTAACCTTTCCAGAGATGTG
ACAGAAGTCCTTATACTTCAGTTGTTCAGTCAGATTGGACCCTGTAAAAGCTGTAAAATGATAACAGAGAAACTCCACTTGGAGATGTTG
GCAGACCAGCCACGAACAACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGT
GGGACTGGGATCATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGTGTACGCGGTGGAGGCCAGTGAGATGGCACAGCACACG
GGGCAGCTGGTCCTGCAGAACGGCTTTGCTGACATCATCACCGTGTACCAGCAGAAGGTGGAGGATGTGGTGCTGCCCGAGAAGGTGGAC
GTGCTGGTGTCTGAGTGGATGGGGACCTGCCTGCTGACCCTGAGGGGCGAGCTGCGCTTCGACATCAGGAAGGCGGGGACCCTGCACGGC
TTCACGGCCTGGTTTAGCGTCCACTTCCAGAGCCTGCAGGAGGGGCAGCCGCCGCAGGTGCTCAGCACCGGGCCCTTCCACCCCACCACA
CACTGGAAGCAGACGCTGTTCATGATGGACGACCCAGTCCCTGTCCATACAGGAGACGTGGTCACGGGTTCAGTTGTGTTGCAGAGAAAC
CCAGTGTGGAGAAGGCACATGTCTGTGGCTCTGAGCTGGGCTGTCACTTCCAGACAAGACCCCACATCTCAAAAAGTTGGAGAAAAAGTC
TTCCCCATCTGGAGATGACAGTTGATGCTTTATTTGGAAAGCAGTGTGCATATCTTGAGGGGTGATGAACACAAGCAAACCAAGTTGCAC
CTGGCTTCTGCACACTCCTGCGAAAGTCGGTGAACATTCACTCCACATTGACCCCTCCCTAGCCTGGCAGGTGACGTCAGGGTCCTTCAC
AGACAAACACGCTTGGGCTCGGCAGGAGCTGCCGTGGCCACCCCCGCTGCCCAGTGTCTGCCCTCTAGAAGTAGGCTGTGTTTCCAGGTG
TTCACCCGTGGTGCCCACAGTGCCGACCCGTGGCTGGGTCGGAGCTCCATGTTCCTAAGCTAGGTCTAGGTCTACACTCCTAGGACGCAC
GCATATCAGCCCGTGTACCCTGTGACAGTGACTGTCCCCACCTCCTATGTTAGTGGTGCCCTTACTGCCGTCGCTCATCCACTCGTGTGG
GACGTAGGATTGCACAGGGCTGTGCCAGTGGCGTGTAGGGAACACTGCCCTGGCTCAGCGTGCGAGCTAAGGTGGTGATGTATGCGATGG
GACTCTGCATGGGATAGTACAGTTGTGTAGACGTCTTCCAAATAAATTATGTGTTGGTCCATCGCACATGCTCAATAAATATTTTTAAAT
GAGTGAATGTCATTGTGTATCCTGTTTTATGCATATATGTTATTTTTTGTAATTACAGGATCATACTATATGCATTGCTTTATAAGTTTT
TCTCAATATTGTGAAAAAACTTCCACATCAGTAGATACATGTCCATAATTTTTTTTTGTATTGTTTTGATTTTTATTAAATTTTATTGAA
ATATA

>90834_90834_7_TIAL1-PRMT2_TIAL1_chr10_121347663_ENST00000369093_PRMT2_chr21_48068369_ENST00000440086_length(amino acids)=275AA_BP=53
LSRDRSVAPTMMEDDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDVGC
GTGIISLFCAHYARPRAVYAVEASEMAQHTGQLVLQNGFADIITVYQQKVEDVVLPEKVDVLVSEWMGTCLLTLRGELRFDIRKAGTLHG
FTAWFSVHFQSLQEGQPPQVLSTGPFHPTTHWKQTLFMMDDPVPVHTGDVVTGSVVLQRNPVWRRHMSVALSWAVTSRQDPTSQKVGEKV
FPIWR

--------------------------------------------------------------
>90834_90834_8_TIAL1-PRMT2_TIAL1_chr10_121347663_ENST00000369093_PRMT2_chr21_48068369_ENST00000451211_length(transcript)=1313nt_BP=159nt
TTGTCCCGGGATCGCTCCGTCGCACCCACCATGATGGAAGACGACGGGCAGCCCCGGACTCTATACGTAGGTAACCTTTCCAGAGATGTG
ACAGAAGTCCTTATACTTCAGTTGTTCAGTCAGATTGGACCCTGTAAAAGCTGTAAAATGATAACAGAGAAACTCCACTTGGAGATGTTG
GCAGACCAGCCACGAACAACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGT
GGGACTGGGATCATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGTGTACGCGGTGGAGGCCAGTGAGATGGCACAGCACACG
GGGCAGCTGGTCCTGCAGAACGGCTTTGCTGACATCATCACCGTGTACCAGCAGAAGGTGGAGGATGTGGTGCTGCCCGAGAAGGTGGAC
GTGCTGGTGTCTGAGTGGATGGGGACCTGCCTGCTGTTTGAGTTCATGATCGAGTCCATCCTGTATGCCCGGGATGCCTGGCTGAAGGAG
GACGGGGTCATTTGGCCCACCATGGCTGCGTTGCACCTTGTGCCCTGCAGTGCTGATAAGGATTATCGTAGCAAGGTGCTCTTCTGGGAC
AACGCGTACGAGTTCAACCTCAGCGCTCTGAAGTTGGAGAAAAAGTCTTCCCCATCTGGAGATGACAGTTGATGCTTTATTTGGAAAGCA
GTGTGCATATCTTGAGGGGTGATGAACACAAGCAAACCAAGTTGCACCTGGCTTCTGCACACTCCTGCGAAAGTCGGTGAACATTCACTC
CACATTGACCCCTCCCTAGCCTGGCAGGTGACGTCAGGGTCCTTCACAGACAAACACGCTTGGGCTCGGCAGGAGCTGCCGTGGCCACCC
CCGCTGCCCAGTGTCTGCCCTCTAGAAGTAGGCTGTGTTTCCAGGTGTTCACCCGTGGTGCCCACAGTGCCGACCCGTGGCTGGGTCGGA
GCTCCATGTTCCTAAGCTAGGTCTAGGTCTACACTCCTAGGACGCACGCATATCAGCCCGTGTACCCTGTGACAGTGACTGTCCCCACCT
CCTATGTTAGTGGTGCCCTTACTGCCGTCGCTCATCCACTCGTGTGGGACGTAGGATTGCACAGGGCTGTGCCAGTGGCGTGTAGGGAAC
ACTGCCCTGGCTCAGCGTGCGAGCTAAGGTGGTGATGTATGCGATGGGACTCTGCATGGGATAGTACAGTTGTGTAGACGTCTTCCAAAT
AAATTATGTGTTGGTCCATCGCACATGCTCAATAAATATTTTTAAATGAGTGA

>90834_90834_8_TIAL1-PRMT2_TIAL1_chr10_121347663_ENST00000369093_PRMT2_chr21_48068369_ENST00000451211_length(amino acids)=233AA_BP=53
LSRDRSVAPTMMEDDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDVGC
GTGIISLFCAHYARPRAVYAVEASEMAQHTGQLVLQNGFADIITVYQQKVEDVVLPEKVDVLVSEWMGTCLLFEFMIESILYARDAWLKE
DGVIWPTMAALHLVPCSADKDYRSKVLFWDNAYEFNLSALKLEKKSSPSGDDS

--------------------------------------------------------------
>90834_90834_9_TIAL1-PRMT2_TIAL1_chr10_121347663_ENST00000369093_PRMT2_chr21_48068369_ENST00000458387_length(transcript)=1309nt_BP=159nt
TTGTCCCGGGATCGCTCCGTCGCACCCACCATGATGGAAGACGACGGGCAGCCCCGGACTCTATACGTAGGTAACCTTTCCAGAGATGTG
ACAGAAGTCCTTATACTTCAGTTGTTCAGTCAGATTGGACCCTGTAAAAGCTGTAAAATGATAACAGAGAAACTCCACTTGGAGATGTTG
GCAGACCAGCCACGAACAACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGT
GGGACTGGGATCATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGTGTACGCGGTGGAGGCCAGTGAGATGGCACAGCACACG
GGGCAGCTGGTCCTGCAGAACGGCTTTGCTGACATCATCACCGTGTACCAGCAGAAGGTGGAGGATGTGGTGCTGCCCGAGAAGGTGGAC
GTGCTGGTGTCTGAGTGGATGGGGACCTGCCTGCTGCACCACACACTGGAAGCAGACGCTGTTCATGATGGACGACCCAGTCCCTGTCCA
TACAGGAGACGTGGTCACGGGTTCAGTTGTGTTGCAGAGAAACCCAGTGTGGAGAAGGCACATGTCTGTGGCTCTGAGCTGGGCTGTCAC
TTCCAGACAAGACCCCACATCTCAAAAAGTTGGAGAAAAAGTCTTCCCCATCTGGAGATGACAGTTGATGCTTTATTTGGAAAGCAGTGT
GCATATCTTGAGGGGTGATGAACACAAGCAAACCAAGTTGCACCTGGCTTCTGCACACTCCTGCGAAAGTCGGTGAACATTCACTCCACA
TTGACCCCTCCCTAGCCTGGCAGGTGACGTCAGGGTCCTTCACAGACAAACACGCTTGGGCTCGGCAGGAGCTGCCGTGGCCACCCCCGC
TGCCCAGTGTCTGCCCTCTAGAAGTAGGCTGTGTTTCCAGGTGTTCACCCGTGGTGCCCACAGTGCCGACCCGTGGCTGGGTCGGAGCTC
CATGTTCCTAAGCTAGGTCTAGGTCTACACTCCTAGGACGCACGCATATCAGCCCGTGTACCCTGTGACAGTGACTGTCCCCACCTCCTA
TGTTAGTGGTGCCCTTACTGCCGTCGCTCATCCACTCGTGTGGGACGTAGGATTGCACAGGGCTGTGCCAGTGGCGTGTAGGGAACACTG
CCCTGGCTCAGCGTGCGAGCTAAGGTGGTGATGTATGCGATGGGACTCTGCATGGGATAGTACAGTTGTGTAGACGTCTTCCAAATAAAT
TATGTGTTGGTCCATCGCACATGCTCAATAAATATTTTTAAATGAGTGA

>90834_90834_9_TIAL1-PRMT2_TIAL1_chr10_121347663_ENST00000369093_PRMT2_chr21_48068369_ENST00000458387_length(amino acids)=245AA_BP=53
LSRDRSVAPTMMEDDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDVGC
GTGIISLFCAHYARPRAVYAVEASEMAQHTGQLVLQNGFADIITVYQQKVEDVVLPEKVDVLVSEWMGTCLLHHTLEADAVHDGRPSPCP
YRRRGHGFSCVAEKPSVEKAHVCGSELGCHFQTRPHISKSWRKSLPHLEMTVDALFGKQCAYLEG

--------------------------------------------------------------
>90834_90834_10_TIAL1-PRMT2_TIAL1_chr10_121347663_ENST00000436547_PRMT2_chr21_48068369_ENST00000291705_length(transcript)=1152nt_BP=174nt
ACCCTGCCCTCCCCCTTGTCCCGGGATCGCTCCGTCGCACCCACCATGATGGAAGACGACGGGCAGCCCCGGACTCTATACGTAGGTAAC
CTTTCCAGAGATGTGACAGAAGTCCTTATACTTCAGTTGTTCAGTCAGATTGGACCCTGTAAAAGCTGTAAAATGATAACAGAGAAACTC
CACTTGGAGATGTTGGCAGACCAGCCACGAACAACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATC
CTGGACGTGGGCTGTGGGACTGGGATCATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGTGTACGCGGTGGAGGCCAGTGAG
ATGGCACAGCACACGGGGCAGCTGGTCCTGCAGAACGGCTTTGCTGACATCATCACCGTGTACCAGCAGAAGGTGGAGGATGTGGTGCTG
CCCGAGAAGGTGGACGTGCTGGTGTCTGAGTGGATGGGGACCTGCCTGCTGGTTGGAGAAAAAGTCTTCCCCATCTGGAGATGACAGTTG
ATGCTTTATTTGGAAAGCAGTGTGCATATCTTGAGGGGTGATGAACACAAGCAAACCAAGTTGCACCTGGCTTCTGCACACTCCTGCGAA
AGTCGGTGAACATTCACTCCACATTGACCCCTCCCTAGCCTGGCAGGTGACGTCAGGGTCCTTCACAGACAAACACGCTTGGGCTCGGCA
GGAGCTGCCGTGGCCACCCCCGCTGCCCAGTGTCTGCCCTCTAGAAGTAGGCTGTGTTTCCAGGTGTTCACCCGTGGTGCCCACAGTGCC
GACCCGTGGCTGGGTCGGAGCTCCATGTTCCTAAGCTAGGTCTAGGTCTACACTCCTAGGACGCACGCATATCAGCCCGTGTACCCTGTG
ACAGTGACTGTCCCCACCTCCTATGTTAGTGGTGCCCTTACTGCCGTCGCTCATCCACTCGTGTGGGACGTAGGATTGCACAGGGCTGTG
CCAGTGGCGTGTAGGGAACACTGCCCTGGCTCAGCGTGCGAGCTAAGGTGGTGATGTATGCGATGGGACTCTGCATGGGATAGTACAGTT
GTGTAGACGTCTTCCAAATAAATTATGTGTTGGTCCATCGCACATGCTCAATAAATATTTTTAAATGAGTGA

>90834_90834_10_TIAL1-PRMT2_TIAL1_chr10_121347663_ENST00000436547_PRMT2_chr21_48068369_ENST00000291705_length(amino acids)=235AA_BP=1
METQPTSRGQTLGSGGGHGSSCRAQACLSVKDPDVTCQAREGSMWSECSPTFAGVCRSQVQLGLLVFITPQDMHTAFQIKHQLSSPDGED
FFSNQQAGPHPLRHQHVHLLGQHHILHLLLVHGDDVSKAVLQDQLPRVLCHLTGLHRVHRSRPRIVCTEETDDPSPTAHVQDDFIRQGFF
ILQDDTVVFSCSWLVCQHLQVEFLCYHFTAFTGSNLTEQLKYKDFCHISGKVTYV

--------------------------------------------------------------
>90834_90834_11_TIAL1-PRMT2_TIAL1_chr10_121347663_ENST00000436547_PRMT2_chr21_48068369_ENST00000334494_length(transcript)=1014nt_BP=174nt
ACCCTGCCCTCCCCCTTGTCCCGGGATCGCTCCGTCGCACCCACCATGATGGAAGACGACGGGCAGCCCCGGACTCTATACGTAGGTAAC
CTTTCCAGAGATGTGACAGAAGTCCTTATACTTCAGTTGTTCAGTCAGATTGGACCCTGTAAAAGCTGTAAAATGATAACAGAGAAACTC
CACTTGGAGATGTTGGCAGACCAGCCACGAACAACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATC
CTGGACGTGGGCTGTGGGACTGGGATCATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGTGTACGCGGTGGAGGCCAGTGAG
ATGGCACAGCACACGGGGCAGCTGGTCCTGCAGAACGGCTTTGCTGACATCATCACCGTGTACCAGCAGAAGGTGGAGGATGTGGTGCTG
CCCGAGAAGGTGGACGTGCTGGTGTCTGAGTGGATGGGGACCTGCCTGCTGGCTGCGCCTCTCCTGAGCTGCCGCATTCTCCCCTGCACC
TGTGCGTCTGGCCCTCTTCACGTCCTCCTGGCCTGCTGTCTGCCTCTCCCCTGCACCTGTGCGTCTGTCCCTCTTCATGTCCTCCTTGCC
TGCTGTCTGCCTGTTCTCAGAGCCCCTCAGCCCTCAGGCCTTCATCTCTCCTGGCCCATCTTCCTACTCTGACGCTGACATGTAGTAAAA
GTCTGAAGACAGAGAAGAGTGCATGTGCGTTTAGCATAGGAGGGGCAGCTTTCAGTCAGTGCAGCAAGGGCATGTAGTTGTTCAGAGATG
GTGCTGGAACGACTGATTTGGAGAAAAGAGGCCCTTCTTCACACCATCTGCTAAAATAAACCTCAGATGGGCTCAAGAGTTAAATATTTA
AGAAAAGGAGGAAACAAAAAAATTGCTACAAGTTTATTTGTTGTTAGGATGGGAAAGGTTTTTCTAAGAACCAAGTTCATAATGAAGCTG
TCAAATAAAATACTTGACAAAAAA

>90834_90834_11_TIAL1-PRMT2_TIAL1_chr10_121347663_ENST00000436547_PRMT2_chr21_48068369_ENST00000334494_length(amino acids)=232AA_BP=57
MPSPLSRDRSVAPTMMEDDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEKLHLEMLADQPRTTKYHSVILQNKESLTDKVIL
DVGCGTGIISLFCAHYARPRAVYAVEASEMAQHTGQLVLQNGFADIITVYQQKVEDVVLPEKVDVLVSEWMGTCLLAAPLLSCRILPCTC
ASGPLHVLLACCLPLPCTCASVPLHVLLACCLPVLRAPQPSGLHLSWPIFLL

--------------------------------------------------------------
>90834_90834_12_TIAL1-PRMT2_TIAL1_chr10_121347663_ENST00000436547_PRMT2_chr21_48068369_ENST00000355680_length(transcript)=1773nt_BP=174nt
ACCCTGCCCTCCCCCTTGTCCCGGGATCGCTCCGTCGCACCCACCATGATGGAAGACGACGGGCAGCCCCGGACTCTATACGTAGGTAAC
CTTTCCAGAGATGTGACAGAAGTCCTTATACTTCAGTTGTTCAGTCAGATTGGACCCTGTAAAAGCTGTAAAATGATAACAGAGAAACTC
CACTTGGAGATGTTGGCAGACCAGCCACGAACAACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATC
CTGGACGTGGGCTGTGGGACTGGGATCATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGTGTACGCGGTGGAGGCCAGTGAG
ATGGCACAGCACACGGGGCAGCTGGTCCTGCAGAACGGCTTTGCTGACATCATCACCGTGTACCAGCAGAAGGTGGAGGATGTGGTGCTG
CCCGAGAAGGTGGACGTGCTGGTGTCTGAGTGGATGGGGACCTGCCTGCTGTTTGAGTTCATGATCGAGTCCATCCTGTATGCCCGGGAT
GCCTGGCTGAAGGAGGACGGGGTCATTTGGCCCACCATGGCTGCGTTGCACCTTGTGCCCTGCAGTGCTGATAAGGATTATCGTAGCAAG
GTGCTCTTCTGGGACAACGCGTACGAGTTCAACCTCAGCGCTCTGAAATCTTTAGCAGTTAAGGAGTTTTTTTCAAAGCCCAAGTATAAC
CACATTTTGAAACCAGAAGACTGTCTCTCTGAACCGTGCACTATATTGCAGTTGGACATGAGAACCGTGCAAATTTCTGATCTAGAGACC
CTGAGGGGCGAGCTGCGCTTCGACATCAGGAAGGCGGGGACCCTGCACGGCTTCACGGCCTGGTTTAGCGTCCACTTCCAGAGCCTGCAG
GAGGGGCAGCCGCCGCAGGTGCTCAGCACCGGGCCCTTCCACCCCACCACACACTGGAAGCAGACGCTGTTCATGATGGACGACCCAGTC
CCTGTCCATACAGGAGACGTGGTCACGGGTTCAGTTGTGTTGCAGAGAAACCCAGTGTGGAGAAGGCACATGTCTGTGGCTCTGAGCTGG
GCTGTCACTTCCAGACAAGACCCCACATCTCAAAAAGTTGGAGAAAAAGTCTTCCCCATCTGGAGATGACAGTTGATGCTTTATTTGGAA
AGCAGTGTGCATATCTTGAGGGGTGATGAACACAAGCAAACCAAGTTGCACCTGGCTTCTGCACACTCCTGCGAAAGTCGGTGAACATTC
ACTCCACATTGACCCCTCCCTAGCCTGGCAGGTGACGTCAGGGTCCTTCACAGACAAACACGCTTGGGCTCGGCAGGAGCTGCCGTGGCC
ACCCCCGCTGCCCAGTGTCTGCCCTCTAGAAGTAGGCTGTGTTTCCAGGTGTTCACCCGTGGTGCCCACAGTGCCGACCCGTGGCTGGGT
CGGAGCTCCATGTTCCTAAGCTAGGTCTAGGTCTACACTCCTAGGACGCACGCATATCAGCCCGTGTACCCTGTGACAGTGACTGTCCCC
ACCTCCTATGTTAGTGGTGCCCTTACTGCCGTCGCTCATCCACTCGTGTGGGACGTAGGATTGCACAGGGCTGTGCCAGTGGCGTGTAGG
GAACACTGCCCTGGCTCAGCGTGCGAGCTAAGGTGGTGATGTATGCGATGGGACTCTGCATGGGATAGTACAGTTGTGTAGACGTCTTCC
AAATAAATTATGTGTTGGTCCATCGCACATGCTCAATAAATATTTTTAAATGAGTGAATGTCA

>90834_90834_12_TIAL1-PRMT2_TIAL1_chr10_121347663_ENST00000436547_PRMT2_chr21_48068369_ENST00000355680_length(amino acids)=381AA_BP=57
MPSPLSRDRSVAPTMMEDDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEKLHLEMLADQPRTTKYHSVILQNKESLTDKVIL
DVGCGTGIISLFCAHYARPRAVYAVEASEMAQHTGQLVLQNGFADIITVYQQKVEDVVLPEKVDVLVSEWMGTCLLFEFMIESILYARDA
WLKEDGVIWPTMAALHLVPCSADKDYRSKVLFWDNAYEFNLSALKSLAVKEFFSKPKYNHILKPEDCLSEPCTILQLDMRTVQISDLETL
RGELRFDIRKAGTLHGFTAWFSVHFQSLQEGQPPQVLSTGPFHPTTHWKQTLFMMDDPVPVHTGDVVTGSVVLQRNPVWRRHMSVALSWA
VTSRQDPTSQKVGEKVFPIWR

--------------------------------------------------------------
>90834_90834_13_TIAL1-PRMT2_TIAL1_chr10_121347663_ENST00000436547_PRMT2_chr21_48068369_ENST00000397628_length(transcript)=655nt_BP=174nt
ACCCTGCCCTCCCCCTTGTCCCGGGATCGCTCCGTCGCACCCACCATGATGGAAGACGACGGGCAGCCCCGGACTCTATACGTAGGTAAC
CTTTCCAGAGATGTGACAGAAGTCCTTATACTTCAGTTGTTCAGTCAGATTGGACCCTGTAAAAGCTGTAAAATGATAACAGAGAAACTC
CACTTGGAGATGTTGGCAGACCAGCCACGAACAACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATC
CTGGACGTGGGCTGTGGGACTGGGATCATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGTGTACGCGGTGGAGGCCAGTGAG
ATGGCACAGCACACGGGGCAGCTGGTCCTGCAGAACGGCTTTGCTGACATCATCACCGTGTACCAGCAGAAGGTGGAGGATGTGGTGCTG
CCCGAGAAGGTGGACGTGCTGGTGTCTGAGTGGATGGGGACCTGCCTGCTGGTGAGGGCGGGCGTGCGGGCAGCTGGGGGCCGGAGCTGG
GGGGCTTCTGAGCACGGGCTCGGCTGGGCCAACCTCAGGATCTCAAGGGTCGTGCGTGATTCATTTTGATGTTTTCCCTAATGTGAGGTC
TAATTAATTTCTTGTGTGGACATTG

>90834_90834_13_TIAL1-PRMT2_TIAL1_chr10_121347663_ENST00000436547_PRMT2_chr21_48068369_ENST00000397628_length(amino acids)=201AA_BP=57
MPSPLSRDRSVAPTMMEDDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEKLHLEMLADQPRTTKYHSVILQNKESLTDKVIL
DVGCGTGIISLFCAHYARPRAVYAVEASEMAQHTGQLVLQNGFADIITVYQQKVEDVVLPEKVDVLVSEWMGTCLLVRAGVRAAGGRSWG
ASEHGLGWANLRISRVVRDSF

--------------------------------------------------------------
>90834_90834_14_TIAL1-PRMT2_TIAL1_chr10_121347663_ENST00000436547_PRMT2_chr21_48068369_ENST00000397637_length(transcript)=1773nt_BP=174nt
ACCCTGCCCTCCCCCTTGTCCCGGGATCGCTCCGTCGCACCCACCATGATGGAAGACGACGGGCAGCCCCGGACTCTATACGTAGGTAAC
CTTTCCAGAGATGTGACAGAAGTCCTTATACTTCAGTTGTTCAGTCAGATTGGACCCTGTAAAAGCTGTAAAATGATAACAGAGAAACTC
CACTTGGAGATGTTGGCAGACCAGCCACGAACAACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATC
CTGGACGTGGGCTGTGGGACTGGGATCATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGTGTACGCGGTGGAGGCCAGTGAG
ATGGCACAGCACACGGGGCAGCTGGTCCTGCAGAACGGCTTTGCTGACATCATCACCGTGTACCAGCAGAAGGTGGAGGATGTGGTGCTG
CCCGAGAAGGTGGACGTGCTGGTGTCTGAGTGGATGGGGACCTGCCTGCTGTTTGAGTTCATGATCGAGTCCATCCTGTATGCCCGGGAT
GCCTGGCTGAAGGAGGACGGGGTCATTTGGCCCACCATGGCTGCGTTGCACCTTGTGCCCTGCAGTGCTGATAAGGATTATCGTAGCAAG
GTGCTCTTCTGGGACAACGCGTACGAGTTCAACCTCAGCGCTCTGAAATCTTTAGCAGTTAAGGAGTTTTTTTCAAAGCCCAAGTATAAC
CACATTTTGAAACCAGAAGACTGTCTCTCTGAACCGTGCACTATATTGCAGTTGGACATGAGAACCGTGCAAATTTCTGATCTAGAGACC
CTGAGGGGCGAGCTGCGCTTCGACATCAGGAAGGCGGGGACCCTGCACGGCTTCACGGCCTGGTTTAGCGTCCACTTCCAGAGCCTGCAG
GAGGGGCAGCCGCCGCAGGTGCTCAGCACCGGGCCCTTCCACCCCACCACACACTGGAAGCAGACGCTGTTCATGATGGACGACCCAGTC
CCTGTCCATACAGGAGACGTGGTCACGGGTTCAGTTGTGTTGCAGAGAAACCCAGTGTGGAGAAGGCACATGTCTGTGGCTCTGAGCTGG
GCTGTCACTTCCAGACAAGACCCCACATCTCAAAAAGTTGGAGAAAAAGTCTTCCCCATCTGGAGATGACAGTTGATGCTTTATTTGGAA
AGCAGTGTGCATATCTTGAGGGGTGATGAACACAAGCAAACCAAGTTGCACCTGGCTTCTGCACACTCCTGCGAAAGTCGGTGAACATTC
ACTCCACATTGACCCCTCCCTAGCCTGGCAGGTGACGTCAGGGTCCTTCACAGACAAACACGCTTGGGCTCGGCAGGAGCTGCCGTGGCC
ACCCCCGCTGCCCAGTGTCTGCCCTCTAGAAGTAGGCTGTGTTTCCAGGTGTTCACCCGTGGTGCCCACAGTGCCGACCCGTGGCTGGGT
CGGAGCTCCATGTTCCTAAGCTAGGTCTAGGTCTACACTCCTAGGACGCACGCATATCAGCCCGTGTACCCTGTGACAGTGACTGTCCCC
ACCTCCTATGTTAGTGGTGCCCTTACTGCCGTCGCTCATCCACTCGTGTGGGACGTAGGATTGCACAGGGCTGTGCCAGTGGCGTGTAGG
GAACACTGCCCTGGCTCAGCGTGCGAGCTAAGGTGGTGATGTATGCGATGGGACTCTGCATGGGATAGTACAGTTGTGTAGACGTCTTCC
AAATAAATTATGTGTTGGTCCATCGCACATGCTCAATAAATATTTTTAAATGAGTGAATGTCA

>90834_90834_14_TIAL1-PRMT2_TIAL1_chr10_121347663_ENST00000436547_PRMT2_chr21_48068369_ENST00000397637_length(amino acids)=381AA_BP=57
MPSPLSRDRSVAPTMMEDDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEKLHLEMLADQPRTTKYHSVILQNKESLTDKVIL
DVGCGTGIISLFCAHYARPRAVYAVEASEMAQHTGQLVLQNGFADIITVYQQKVEDVVLPEKVDVLVSEWMGTCLLFEFMIESILYARDA
WLKEDGVIWPTMAALHLVPCSADKDYRSKVLFWDNAYEFNLSALKSLAVKEFFSKPKYNHILKPEDCLSEPCTILQLDMRTVQISDLETL
RGELRFDIRKAGTLHGFTAWFSVHFQSLQEGQPPQVLSTGPFHPTTHWKQTLFMMDDPVPVHTGDVVTGSVVLQRNPVWRRHMSVALSWA
VTSRQDPTSQKVGEKVFPIWR

--------------------------------------------------------------
>90834_90834_15_TIAL1-PRMT2_TIAL1_chr10_121347663_ENST00000436547_PRMT2_chr21_48068369_ENST00000397638_length(transcript)=1773nt_BP=174nt
ACCCTGCCCTCCCCCTTGTCCCGGGATCGCTCCGTCGCACCCACCATGATGGAAGACGACGGGCAGCCCCGGACTCTATACGTAGGTAAC
CTTTCCAGAGATGTGACAGAAGTCCTTATACTTCAGTTGTTCAGTCAGATTGGACCCTGTAAAAGCTGTAAAATGATAACAGAGAAACTC
CACTTGGAGATGTTGGCAGACCAGCCACGAACAACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATC
CTGGACGTGGGCTGTGGGACTGGGATCATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGTGTACGCGGTGGAGGCCAGTGAG
ATGGCACAGCACACGGGGCAGCTGGTCCTGCAGAACGGCTTTGCTGACATCATCACCGTGTACCAGCAGAAGGTGGAGGATGTGGTGCTG
CCCGAGAAGGTGGACGTGCTGGTGTCTGAGTGGATGGGGACCTGCCTGCTGTTTGAGTTCATGATCGAGTCCATCCTGTATGCCCGGGAT
GCCTGGCTGAAGGAGGACGGGGTCATTTGGCCCACCATGGCTGCGTTGCACCTTGTGCCCTGCAGTGCTGATAAGGATTATCGTAGCAAG
GTGCTCTTCTGGGACAACGCGTACGAGTTCAACCTCAGCGCTCTGAAATCTTTAGCAGTTAAGGAGTTTTTTTCAAAGCCCAAGTATAAC
CACATTTTGAAACCAGAAGACTGTCTCTCTGAACCGTGCACTATATTGCAGTTGGACATGAGAACCGTGCAAATTTCTGATCTAGAGACC
CTGAGGGGCGAGCTGCGCTTCGACATCAGGAAGGCGGGGACCCTGCACGGCTTCACGGCCTGGTTTAGCGTCCACTTCCAGAGCCTGCAG
GAGGGGCAGCCGCCGCAGGTGCTCAGCACCGGGCCCTTCCACCCCACCACACACTGGAAGCAGACGCTGTTCATGATGGACGACCCAGTC
CCTGTCCATACAGGAGACGTGGTCACGGGTTCAGTTGTGTTGCAGAGAAACCCAGTGTGGAGAAGGCACATGTCTGTGGCTCTGAGCTGG
GCTGTCACTTCCAGACAAGACCCCACATCTCAAAAAGTTGGAGAAAAAGTCTTCCCCATCTGGAGATGACAGTTGATGCTTTATTTGGAA
AGCAGTGTGCATATCTTGAGGGGTGATGAACACAAGCAAACCAAGTTGCACCTGGCTTCTGCACACTCCTGCGAAAGTCGGTGAACATTC
ACTCCACATTGACCCCTCCCTAGCCTGGCAGGTGACGTCAGGGTCCTTCACAGACAAACACGCTTGGGCTCGGCAGGAGCTGCCGTGGCC
ACCCCCGCTGCCCAGTGTCTGCCCTCTAGAAGTAGGCTGTGTTTCCAGGTGTTCACCCGTGGTGCCCACAGTGCCGACCCGTGGCTGGGT
CGGAGCTCCATGTTCCTAAGCTAGGTCTAGGTCTACACTCCTAGGACGCACGCATATCAGCCCGTGTACCCTGTGACAGTGACTGTCCCC
ACCTCCTATGTTAGTGGTGCCCTTACTGCCGTCGCTCATCCACTCGTGTGGGACGTAGGATTGCACAGGGCTGTGCCAGTGGCGTGTAGG
GAACACTGCCCTGGCTCAGCGTGCGAGCTAAGGTGGTGATGTATGCGATGGGACTCTGCATGGGATAGTACAGTTGTGTAGACGTCTTCC
AAATAAATTATGTGTTGGTCCATCGCACATGCTCAATAAATATTTTTAAATGAGTGAATGTCA

>90834_90834_15_TIAL1-PRMT2_TIAL1_chr10_121347663_ENST00000436547_PRMT2_chr21_48068369_ENST00000397638_length(amino acids)=381AA_BP=57
MPSPLSRDRSVAPTMMEDDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEKLHLEMLADQPRTTKYHSVILQNKESLTDKVIL
DVGCGTGIISLFCAHYARPRAVYAVEASEMAQHTGQLVLQNGFADIITVYQQKVEDVVLPEKVDVLVSEWMGTCLLFEFMIESILYARDA
WLKEDGVIWPTMAALHLVPCSADKDYRSKVLFWDNAYEFNLSALKSLAVKEFFSKPKYNHILKPEDCLSEPCTILQLDMRTVQISDLETL
RGELRFDIRKAGTLHGFTAWFSVHFQSLQEGQPPQVLSTGPFHPTTHWKQTLFMMDDPVPVHTGDVVTGSVVLQRNPVWRRHMSVALSWA
VTSRQDPTSQKVGEKVFPIWR

--------------------------------------------------------------
>90834_90834_16_TIAL1-PRMT2_TIAL1_chr10_121347663_ENST00000436547_PRMT2_chr21_48068369_ENST00000440086_length(transcript)=1640nt_BP=174nt
ACCCTGCCCTCCCCCTTGTCCCGGGATCGCTCCGTCGCACCCACCATGATGGAAGACGACGGGCAGCCCCGGACTCTATACGTAGGTAAC
CTTTCCAGAGATGTGACAGAAGTCCTTATACTTCAGTTGTTCAGTCAGATTGGACCCTGTAAAAGCTGTAAAATGATAACAGAGAAACTC
CACTTGGAGATGTTGGCAGACCAGCCACGAACAACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATC
CTGGACGTGGGCTGTGGGACTGGGATCATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGTGTACGCGGTGGAGGCCAGTGAG
ATGGCACAGCACACGGGGCAGCTGGTCCTGCAGAACGGCTTTGCTGACATCATCACCGTGTACCAGCAGAAGGTGGAGGATGTGGTGCTG
CCCGAGAAGGTGGACGTGCTGGTGTCTGAGTGGATGGGGACCTGCCTGCTGACCCTGAGGGGCGAGCTGCGCTTCGACATCAGGAAGGCG
GGGACCCTGCACGGCTTCACGGCCTGGTTTAGCGTCCACTTCCAGAGCCTGCAGGAGGGGCAGCCGCCGCAGGTGCTCAGCACCGGGCCC
TTCCACCCCACCACACACTGGAAGCAGACGCTGTTCATGATGGACGACCCAGTCCCTGTCCATACAGGAGACGTGGTCACGGGTTCAGTT
GTGTTGCAGAGAAACCCAGTGTGGAGAAGGCACATGTCTGTGGCTCTGAGCTGGGCTGTCACTTCCAGACAAGACCCCACATCTCAAAAA
GTTGGAGAAAAAGTCTTCCCCATCTGGAGATGACAGTTGATGCTTTATTTGGAAAGCAGTGTGCATATCTTGAGGGGTGATGAACACAAG
CAAACCAAGTTGCACCTGGCTTCTGCACACTCCTGCGAAAGTCGGTGAACATTCACTCCACATTGACCCCTCCCTAGCCTGGCAGGTGAC
GTCAGGGTCCTTCACAGACAAACACGCTTGGGCTCGGCAGGAGCTGCCGTGGCCACCCCCGCTGCCCAGTGTCTGCCCTCTAGAAGTAGG
CTGTGTTTCCAGGTGTTCACCCGTGGTGCCCACAGTGCCGACCCGTGGCTGGGTCGGAGCTCCATGTTCCTAAGCTAGGTCTAGGTCTAC
ACTCCTAGGACGCACGCATATCAGCCCGTGTACCCTGTGACAGTGACTGTCCCCACCTCCTATGTTAGTGGTGCCCTTACTGCCGTCGCT
CATCCACTCGTGTGGGACGTAGGATTGCACAGGGCTGTGCCAGTGGCGTGTAGGGAACACTGCCCTGGCTCAGCGTGCGAGCTAAGGTGG
TGATGTATGCGATGGGACTCTGCATGGGATAGTACAGTTGTGTAGACGTCTTCCAAATAAATTATGTGTTGGTCCATCGCACATGCTCAA
TAAATATTTTTAAATGAGTGAATGTCATTGTGTATCCTGTTTTATGCATATATGTTATTTTTTGTAATTACAGGATCATACTATATGCAT
TGCTTTATAAGTTTTTCTCAATATTGTGAAAAAACTTCCACATCAGTAGATACATGTCCATAATTTTTTTTTGTATTGTTTTGATTTTTA
TTAAATTTTATTGAAATATA

>90834_90834_16_TIAL1-PRMT2_TIAL1_chr10_121347663_ENST00000436547_PRMT2_chr21_48068369_ENST00000440086_length(amino acids)=279AA_BP=57
MPSPLSRDRSVAPTMMEDDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEKLHLEMLADQPRTTKYHSVILQNKESLTDKVIL
DVGCGTGIISLFCAHYARPRAVYAVEASEMAQHTGQLVLQNGFADIITVYQQKVEDVVLPEKVDVLVSEWMGTCLLTLRGELRFDIRKAG
TLHGFTAWFSVHFQSLQEGQPPQVLSTGPFHPTTHWKQTLFMMDDPVPVHTGDVVTGSVVLQRNPVWRRHMSVALSWAVTSRQDPTSQKV
GEKVFPIWR

--------------------------------------------------------------
>90834_90834_17_TIAL1-PRMT2_TIAL1_chr10_121347663_ENST00000436547_PRMT2_chr21_48068369_ENST00000451211_length(transcript)=1328nt_BP=174nt
ACCCTGCCCTCCCCCTTGTCCCGGGATCGCTCCGTCGCACCCACCATGATGGAAGACGACGGGCAGCCCCGGACTCTATACGTAGGTAAC
CTTTCCAGAGATGTGACAGAAGTCCTTATACTTCAGTTGTTCAGTCAGATTGGACCCTGTAAAAGCTGTAAAATGATAACAGAGAAACTC
CACTTGGAGATGTTGGCAGACCAGCCACGAACAACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATC
CTGGACGTGGGCTGTGGGACTGGGATCATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGTGTACGCGGTGGAGGCCAGTGAG
ATGGCACAGCACACGGGGCAGCTGGTCCTGCAGAACGGCTTTGCTGACATCATCACCGTGTACCAGCAGAAGGTGGAGGATGTGGTGCTG
CCCGAGAAGGTGGACGTGCTGGTGTCTGAGTGGATGGGGACCTGCCTGCTGTTTGAGTTCATGATCGAGTCCATCCTGTATGCCCGGGAT
GCCTGGCTGAAGGAGGACGGGGTCATTTGGCCCACCATGGCTGCGTTGCACCTTGTGCCCTGCAGTGCTGATAAGGATTATCGTAGCAAG
GTGCTCTTCTGGGACAACGCGTACGAGTTCAACCTCAGCGCTCTGAAGTTGGAGAAAAAGTCTTCCCCATCTGGAGATGACAGTTGATGC
TTTATTTGGAAAGCAGTGTGCATATCTTGAGGGGTGATGAACACAAGCAAACCAAGTTGCACCTGGCTTCTGCACACTCCTGCGAAAGTC
GGTGAACATTCACTCCACATTGACCCCTCCCTAGCCTGGCAGGTGACGTCAGGGTCCTTCACAGACAAACACGCTTGGGCTCGGCAGGAG
CTGCCGTGGCCACCCCCGCTGCCCAGTGTCTGCCCTCTAGAAGTAGGCTGTGTTTCCAGGTGTTCACCCGTGGTGCCCACAGTGCCGACC
CGTGGCTGGGTCGGAGCTCCATGTTCCTAAGCTAGGTCTAGGTCTACACTCCTAGGACGCACGCATATCAGCCCGTGTACCCTGTGACAG
TGACTGTCCCCACCTCCTATGTTAGTGGTGCCCTTACTGCCGTCGCTCATCCACTCGTGTGGGACGTAGGATTGCACAGGGCTGTGCCAG
TGGCGTGTAGGGAACACTGCCCTGGCTCAGCGTGCGAGCTAAGGTGGTGATGTATGCGATGGGACTCTGCATGGGATAGTACAGTTGTGT
AGACGTCTTCCAAATAAATTATGTGTTGGTCCATCGCACATGCTCAATAAATATTTTTAAATGAGTGA

>90834_90834_17_TIAL1-PRMT2_TIAL1_chr10_121347663_ENST00000436547_PRMT2_chr21_48068369_ENST00000451211_length(amino acids)=237AA_BP=57
MPSPLSRDRSVAPTMMEDDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEKLHLEMLADQPRTTKYHSVILQNKESLTDKVIL
DVGCGTGIISLFCAHYARPRAVYAVEASEMAQHTGQLVLQNGFADIITVYQQKVEDVVLPEKVDVLVSEWMGTCLLFEFMIESILYARDA
WLKEDGVIWPTMAALHLVPCSADKDYRSKVLFWDNAYEFNLSALKLEKKSSPSGDDS

--------------------------------------------------------------
>90834_90834_18_TIAL1-PRMT2_TIAL1_chr10_121347663_ENST00000436547_PRMT2_chr21_48068369_ENST00000458387_length(transcript)=1324nt_BP=174nt
ACCCTGCCCTCCCCCTTGTCCCGGGATCGCTCCGTCGCACCCACCATGATGGAAGACGACGGGCAGCCCCGGACTCTATACGTAGGTAAC
CTTTCCAGAGATGTGACAGAAGTCCTTATACTTCAGTTGTTCAGTCAGATTGGACCCTGTAAAAGCTGTAAAATGATAACAGAGAAACTC
CACTTGGAGATGTTGGCAGACCAGCCACGAACAACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATC
CTGGACGTGGGCTGTGGGACTGGGATCATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGTGTACGCGGTGGAGGCCAGTGAG
ATGGCACAGCACACGGGGCAGCTGGTCCTGCAGAACGGCTTTGCTGACATCATCACCGTGTACCAGCAGAAGGTGGAGGATGTGGTGCTG
CCCGAGAAGGTGGACGTGCTGGTGTCTGAGTGGATGGGGACCTGCCTGCTGCACCACACACTGGAAGCAGACGCTGTTCATGATGGACGA
CCCAGTCCCTGTCCATACAGGAGACGTGGTCACGGGTTCAGTTGTGTTGCAGAGAAACCCAGTGTGGAGAAGGCACATGTCTGTGGCTCT
GAGCTGGGCTGTCACTTCCAGACAAGACCCCACATCTCAAAAAGTTGGAGAAAAAGTCTTCCCCATCTGGAGATGACAGTTGATGCTTTA
TTTGGAAAGCAGTGTGCATATCTTGAGGGGTGATGAACACAAGCAAACCAAGTTGCACCTGGCTTCTGCACACTCCTGCGAAAGTCGGTG
AACATTCACTCCACATTGACCCCTCCCTAGCCTGGCAGGTGACGTCAGGGTCCTTCACAGACAAACACGCTTGGGCTCGGCAGGAGCTGC
CGTGGCCACCCCCGCTGCCCAGTGTCTGCCCTCTAGAAGTAGGCTGTGTTTCCAGGTGTTCACCCGTGGTGCCCACAGTGCCGACCCGTG
GCTGGGTCGGAGCTCCATGTTCCTAAGCTAGGTCTAGGTCTACACTCCTAGGACGCACGCATATCAGCCCGTGTACCCTGTGACAGTGAC
TGTCCCCACCTCCTATGTTAGTGGTGCCCTTACTGCCGTCGCTCATCCACTCGTGTGGGACGTAGGATTGCACAGGGCTGTGCCAGTGGC
GTGTAGGGAACACTGCCCTGGCTCAGCGTGCGAGCTAAGGTGGTGATGTATGCGATGGGACTCTGCATGGGATAGTACAGTTGTGTAGAC
GTCTTCCAAATAAATTATGTGTTGGTCCATCGCACATGCTCAATAAATATTTTTAAATGAGTGA

>90834_90834_18_TIAL1-PRMT2_TIAL1_chr10_121347663_ENST00000436547_PRMT2_chr21_48068369_ENST00000458387_length(amino acids)=249AA_BP=57
MPSPLSRDRSVAPTMMEDDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEKLHLEMLADQPRTTKYHSVILQNKESLTDKVIL
DVGCGTGIISLFCAHYARPRAVYAVEASEMAQHTGQLVLQNGFADIITVYQQKVEDVVLPEKVDVLVSEWMGTCLLHHTLEADAVHDGRP
SPCPYRRRGHGFSCVAEKPSVEKAHVCGSELGCHFQTRPHISKSWRKSLPHLEMTVDALFGKQCAYLEG

--------------------------------------------------------------

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Fusion Gene PPI Analysis for TIAL1-PRMT2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgenePRMT2chr10:121347663chr21:48068369ENST0000033449437133_275109.0285.0ESR1
TgenePRMT2chr10:121347663chr21:48068369ENST00000355680412133_275109.0434.0ESR1
TgenePRMT2chr10:121347663chr21:48068369ENST00000397637311133_275109.0434.0ESR1
TgenePRMT2chr10:121347663chr21:48068369ENST00000397638311133_275109.0434.0ESR1
TgenePRMT2chr10:121347663chr21:48068369ENST0000044008639133_275109.0332.0ESR1


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
TgenePRMT2chr10:121347663chr21:48068369ENST00000334494371_277109.0285.0ESR1
TgenePRMT2chr10:121347663chr21:48068369ENST000003556804121_277109.0434.0ESR1
TgenePRMT2chr10:121347663chr21:48068369ENST000003976373111_277109.0434.0ESR1
TgenePRMT2chr10:121347663chr21:48068369ENST000003976383111_277109.0434.0ESR1
TgenePRMT2chr10:121347663chr21:48068369ENST00000440086391_277109.0332.0ESR1
TgenePRMT2chr10:121347663chr21:48068369ENST000003344943783_207109.0285.0RB1
TgenePRMT2chr10:121347663chr21:48068369ENST0000035568041283_207109.0434.0RB1
TgenePRMT2chr10:121347663chr21:48068369ENST0000039763731183_207109.0434.0RB1
TgenePRMT2chr10:121347663chr21:48068369ENST0000039763831183_207109.0434.0RB1
TgenePRMT2chr10:121347663chr21:48068369ENST000004400863983_207109.0332.0RB1


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for TIAL1-PRMT2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for TIAL1-PRMT2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneTIAL1C0023893Liver Cirrhosis, Experimental1CTD_human