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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:ACTG1-MITF (FusionGDB2 ID:HG71TG4286) |
Fusion Gene Summary for ACTG1-MITF |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: ACTG1-MITF | Fusion gene ID: hg71tg4286 | Hgene | Tgene | Gene symbol | ACTG1 | MITF | Gene ID | 71 | 4286 |
| Gene name | actin gamma 1 | melanocyte inducing transcription factor | |
| Synonyms | ACT|ACTG|DFNA20|DFNA26|HEL-176 | CMM8|COMMAD|MI|WS2|WS2A|bHLHe32 | |
| Cytomap | ('ACTG1')('MITF') 17q25.3 | 3p13 | |
| Type of gene | protein-coding | protein-coding | |
| Description | actin, cytoplasmic 2cytoskeletal gamma-actinepididymis luminal protein 176 | microphthalmia-associated transcription factorclass E basic helix-loop-helix protein 32melanogenesis associated transcription factormicrophtalmia-associated transcription factor | |
| Modification date | 20200327 | 20200329 | |
| UniProtAcc | P63261 | O75030 | |
| Ensembl transtripts involved in fusion gene | ENST00000331925, ENST00000573283, ENST00000575087, ENST00000575842, | ||
| Fusion gene scores | * DoF score | 51 X 36 X 13=23868 | 10 X 9 X 7=630 |
| # samples | 58 | 10 | |
| ** MAII score | log2(58/23868*10)=-5.36288097153997 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(10/630*10)=-2.65535182861255 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: ACTG1 [Title/Abstract] AND MITF [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | |||
| Anticipated loss of major functional domain due to fusion event. | ACTG1-MITF seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF. ACTG1-MITF seems lost the major protein functional domain in Tgene partner, which is a CGC due to the frame-shifted ORF. ACTG1-MITF seems lost the major protein functional domain in Tgene partner, which is a transcription factor due to the frame-shifted ORF. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | MITF | GO:0010628 | positive regulation of gene expression | 22234890 |
| Tgene | MITF | GO:0045893 | positive regulation of transcription, DNA-templated | 9647758 |
| Tgene | MITF | GO:0045944 | positive regulation of transcription by RNA polymerase II | 20530484|21209915 |
| Tgene | MITF | GO:0065003 | protein-containing complex assembly | 20530484 |
| Tgene | MITF | GO:2000144 | positive regulation of DNA-templated transcription, initiation | 8995290|12204775 |
| Tgene | MITF | GO:2001141 | regulation of RNA biosynthetic process | 16411896 |
| Fusion gene information * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerKB3 | . | . | ACTG1 | chr17 | 79478929 | - | MITF | chr3 | 69986973 | + |
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Fusion Gene ORF analysis for ACTG1-MITF |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-3UTR | ENST00000331925 | ENST00000394348 | ACTG1 | chr17 | 79478929 | - | MITF | chr3 | 69986973 | + |
| 5CDS-3UTR | ENST00000573283 | ENST00000394348 | ACTG1 | chr17 | 79478929 | - | MITF | chr3 | 69986973 | + |
| 5CDS-3UTR | ENST00000575087 | ENST00000394348 | ACTG1 | chr17 | 79478929 | - | MITF | chr3 | 69986973 | + |
| 5CDS-3UTR | ENST00000575842 | ENST00000394348 | ACTG1 | chr17 | 79478929 | - | MITF | chr3 | 69986973 | + |
| Frame-shift | ENST00000331925 | ENST00000314557 | ACTG1 | chr17 | 79478929 | - | MITF | chr3 | 69986973 | + |
| Frame-shift | ENST00000331925 | ENST00000314589 | ACTG1 | chr17 | 79478929 | - | MITF | chr3 | 69986973 | + |
| Frame-shift | ENST00000331925 | ENST00000328528 | ACTG1 | chr17 | 79478929 | - | MITF | chr3 | 69986973 | + |
| Frame-shift | ENST00000331925 | ENST00000352241 | ACTG1 | chr17 | 79478929 | - | MITF | chr3 | 69986973 | + |
| Frame-shift | ENST00000331925 | ENST00000394351 | ACTG1 | chr17 | 79478929 | - | MITF | chr3 | 69986973 | + |
| Frame-shift | ENST00000331925 | ENST00000394355 | ACTG1 | chr17 | 79478929 | - | MITF | chr3 | 69986973 | + |
| Frame-shift | ENST00000331925 | ENST00000448226 | ACTG1 | chr17 | 79478929 | - | MITF | chr3 | 69986973 | + |
| Frame-shift | ENST00000331925 | ENST00000472437 | ACTG1 | chr17 | 79478929 | - | MITF | chr3 | 69986973 | + |
| Frame-shift | ENST00000331925 | ENST00000531774 | ACTG1 | chr17 | 79478929 | - | MITF | chr3 | 69986973 | + |
| Frame-shift | ENST00000573283 | ENST00000314557 | ACTG1 | chr17 | 79478929 | - | MITF | chr3 | 69986973 | + |
| Frame-shift | ENST00000573283 | ENST00000314589 | ACTG1 | chr17 | 79478929 | - | MITF | chr3 | 69986973 | + |
| Frame-shift | ENST00000573283 | ENST00000328528 | ACTG1 | chr17 | 79478929 | - | MITF | chr3 | 69986973 | + |
| Frame-shift | ENST00000573283 | ENST00000352241 | ACTG1 | chr17 | 79478929 | - | MITF | chr3 | 69986973 | + |
| Frame-shift | ENST00000573283 | ENST00000394351 | ACTG1 | chr17 | 79478929 | - | MITF | chr3 | 69986973 | + |
| Frame-shift | ENST00000573283 | ENST00000394355 | ACTG1 | chr17 | 79478929 | - | MITF | chr3 | 69986973 | + |
| Frame-shift | ENST00000573283 | ENST00000448226 | ACTG1 | chr17 | 79478929 | - | MITF | chr3 | 69986973 | + |
| Frame-shift | ENST00000573283 | ENST00000472437 | ACTG1 | chr17 | 79478929 | - | MITF | chr3 | 69986973 | + |
| Frame-shift | ENST00000573283 | ENST00000531774 | ACTG1 | chr17 | 79478929 | - | MITF | chr3 | 69986973 | + |
| Frame-shift | ENST00000575087 | ENST00000314557 | ACTG1 | chr17 | 79478929 | - | MITF | chr3 | 69986973 | + |
| Frame-shift | ENST00000575087 | ENST00000314589 | ACTG1 | chr17 | 79478929 | - | MITF | chr3 | 69986973 | + |
| Frame-shift | ENST00000575087 | ENST00000328528 | ACTG1 | chr17 | 79478929 | - | MITF | chr3 | 69986973 | + |
| Frame-shift | ENST00000575087 | ENST00000352241 | ACTG1 | chr17 | 79478929 | - | MITF | chr3 | 69986973 | + |
| Frame-shift | ENST00000575087 | ENST00000394351 | ACTG1 | chr17 | 79478929 | - | MITF | chr3 | 69986973 | + |
| Frame-shift | ENST00000575087 | ENST00000394355 | ACTG1 | chr17 | 79478929 | - | MITF | chr3 | 69986973 | + |
| Frame-shift | ENST00000575087 | ENST00000448226 | ACTG1 | chr17 | 79478929 | - | MITF | chr3 | 69986973 | + |
| Frame-shift | ENST00000575087 | ENST00000472437 | ACTG1 | chr17 | 79478929 | - | MITF | chr3 | 69986973 | + |
| Frame-shift | ENST00000575087 | ENST00000531774 | ACTG1 | chr17 | 79478929 | - | MITF | chr3 | 69986973 | + |
| In-frame | ENST00000575842 | ENST00000314557 | ACTG1 | chr17 | 79478929 | - | MITF | chr3 | 69986973 | + |
| In-frame | ENST00000575842 | ENST00000314589 | ACTG1 | chr17 | 79478929 | - | MITF | chr3 | 69986973 | + |
| In-frame | ENST00000575842 | ENST00000328528 | ACTG1 | chr17 | 79478929 | - | MITF | chr3 | 69986973 | + |
| In-frame | ENST00000575842 | ENST00000352241 | ACTG1 | chr17 | 79478929 | - | MITF | chr3 | 69986973 | + |
| In-frame | ENST00000575842 | ENST00000394351 | ACTG1 | chr17 | 79478929 | - | MITF | chr3 | 69986973 | + |
| In-frame | ENST00000575842 | ENST00000394355 | ACTG1 | chr17 | 79478929 | - | MITF | chr3 | 69986973 | + |
| In-frame | ENST00000575842 | ENST00000448226 | ACTG1 | chr17 | 79478929 | - | MITF | chr3 | 69986973 | + |
| In-frame | ENST00000575842 | ENST00000472437 | ACTG1 | chr17 | 79478929 | - | MITF | chr3 | 69986973 | + |
| In-frame | ENST00000575842 | ENST00000531774 | ACTG1 | chr17 | 79478929 | - | MITF | chr3 | 69986973 | + |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000575842 | ACTG1 | chr17 | 79478929 | - | ENST00000352241 | MITF | chr3 | 69986973 | + | 5087 | 790 | 397 | 1998 | 533 |
| ENST00000575842 | ACTG1 | chr17 | 79478929 | - | ENST00000448226 | MITF | chr3 | 69986973 | + | 2798 | 790 | 397 | 2016 | 539 |
| ENST00000575842 | ACTG1 | chr17 | 79478929 | - | ENST00000472437 | MITF | chr3 | 69986973 | + | 2398 | 790 | 397 | 1998 | 533 |
| ENST00000575842 | ACTG1 | chr17 | 79478929 | - | ENST00000328528 | MITF | chr3 | 69986973 | + | 5088 | 790 | 397 | 1998 | 533 |
| ENST00000575842 | ACTG1 | chr17 | 79478929 | - | ENST00000314589 | MITF | chr3 | 69986973 | + | 2398 | 790 | 397 | 1998 | 533 |
| ENST00000575842 | ACTG1 | chr17 | 79478929 | - | ENST00000394355 | MITF | chr3 | 69986973 | + | 5084 | 790 | 397 | 1998 | 533 |
| ENST00000575842 | ACTG1 | chr17 | 79478929 | - | ENST00000314557 | MITF | chr3 | 69986973 | + | 2419 | 790 | 397 | 1998 | 533 |
| ENST00000575842 | ACTG1 | chr17 | 79478929 | - | ENST00000394351 | MITF | chr3 | 69986973 | + | 2593 | 790 | 397 | 2016 | 539 |
| ENST00000575842 | ACTG1 | chr17 | 79478929 | - | ENST00000531774 | MITF | chr3 | 69986973 | + | 1831 | 790 | 397 | 1830 | 478 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
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Fusion Genomic Features for ACTG1-MITF |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
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Fusion Protein Features for ACTG1-MITF |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr17:/chr3:) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| ACTG1 | MITF |
| FUNCTION: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. {ECO:0000305|PubMed:29581253}. | FUNCTION: Transcription factor that regulates the expression of genes with essential roles in cell differentiation, proliferation and survival. Binds to M-boxes (5'-TCATGTG-3') and symmetrical DNA sequences (E-boxes) (5'-CACGTG-3') found in the promoters of target genes, such as BCL2 and tyrosinase (TYR). Plays an important role in melanocyte development by regulating the expression of tyrosinase (TYR) and tyrosinase-related protein 1 (TYRP1). Plays a critical role in the differentiation of various cell types, such as neural crest-derived melanocytes, mast cells, osteoclasts and optic cup-derived retinal pigment epithelium. {ECO:0000269|PubMed:10587587, ECO:0000269|PubMed:22647378, ECO:0000269|PubMed:27889061, ECO:0000269|PubMed:9647758}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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Fusion Gene Sequence for ACTG1-MITF |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >1695_1695_1_ACTG1-MITF_ACTG1_chr17_79478929_ENST00000575842_MITF_chr3_69986973_ENST00000314557_length(transcript)=2419nt_BP=790nt CTCTCGCACTCTGTTCTTCCGCCGCTCCGCCGTCGCGTTTCTCTGCCGGTGAGCGCCCCGCCCCGGGGCCTGAGCTGGACGTCGCAGGCC TGCGCCCCCCGACCCCGGCTGGCCCCGCTTCCAGCTGCCGAGGCCTCGTCGCGCCTTCCCCGGGAACAAAAGGCGGGGTGGGCCGGGTCA GGCGGACGGGGCTGGGGGGGCGCCGGGGGTCCAGGGCGGGGCCCGGCCGCAGTGCAGACTTCCGAGCCGTGGACGTTACGTAAAAGGCCC GGCCTTCGGTTCCAGGCGGTTGCGATCTTGGAGGCCACGGCCGCTGGGGTTGGGGCAGGGCCGAGGCTTCCCCGCGGGAGGGCATTAGGT GGCTGTGGGGAGGGGACCGTGTTACAGACGCGCCCGCCTGAGTCCATCCTTTTCCGGGCAGGTCGCAATGGAAGAAGAGATCGCCGCGCT GGTCATTGACAATGGCTCCGGCATGTGCAAAGCTGGTTTTGCTGGGGACGACGCTCCCCGAGCCGTGTTTCCTTCCATCGTCGGGCGCCC CAGACACCAGGGCGTCATGGTGGGCATGGGCCAGAAGGACTCCTACGTGGGCGACGAGGCCCAGAGCAAGCGTGGCATCCTGACCCTGAA GTACCCCATTGAGCATGGCATCGTCACCAACTGGGACGACATGGAGAAGATCTGGCACCACACCTTCTACAACGAGCTGCGCGTGGCCCC GGAGGAGCACCCAGTGCTGCTGACCGAGGCCCCCCTGAACCCCAAGGCCAACAGAGAGAAGATGACTCAGGTGCAGACCCACCTCGAAAA CCCCACCAAGTACCACATACAGCAAGCCCAACGGCAGCAGGTAAAGCAGTACCTTTCTACCACTTTAGCAAATAAACATGCCAACCAAGT CCTGAGCTTGCCATGTCCAAACCAGCCTGGCGATCATGTCATGCCACCGGTGCCGGGGAGCAGCGCACCCAACAGCCCCATGGCTATGCT TACGCTTAACTCCAACTGTGAAAAAGAGGGATTTTATAAGTTTGAAGAGCAAAACAGGGCAGAGAGCGAGTGCCCAGGCATGAACACACA TTCACGAGCGTCCTGTATGCAGATGGATGATGTAATCGATGACATCATTAGCCTAGAATCAAGTTATAATGAGGAAATCTTGGGCTTGAT GGATCCTGCTTTGCAAATGGCAAATACGTTGCCTGTCTCGGGAAACTTGATTGATCTTTATGGAAACCAAGGTCTGCCCCCACCAGGCCT CACCATCAGCAACTCCTGTCCAGCCAACCTTCCCAACATAAAAAGGGAGCTCACAGAGTCTGAAGCAAGAGCACTGGCCAAAGAGAGGCA GAAAAAGGACAATCACAACCTGATTGAACGAAGAAGAAGATTTAACATAAATGACCGCATTAAAGAACTAGGTACTTTGATTCCCAAGTC AAATGATCCAGACATGCGCTGGAACAAGGGAACCATCTTAAAAGCATCCGTGGACTATATCCGAAAGTTGCAACGAGAACAGCAACGCGC AAAAGAACTTGAAAACCGACAGAAGAAACTGGAGCACGCCAACCGGCATTTGTTGCTCAGAATACAGGAACTTGAAATGCAGGCTCGAGC TCATGGACTTTCCCTTATTCCATCCACGGGTCTCTGCTCTCCAGATTTGGTGAATCGGATCATCAAGCAAGAACCCGTTCTTGAGAACTG CAGCCAAGACCTCCTTCAGCATCATGCAGACCTAACCTGTACAACAACTCTCGATCTCACGGATGGCACCATCACCTTCAACAACAACCT CGGAACTGGGACTGAGGCCAACCAAGCCTATAGTGTCCCCACAAAAATGGGATCCAAACTGGAAGACATCCTGATGGACGACACCCTTTC TCCCGTCGGTGTCACTGATCCACTCCTTTCCTCAGTGTCCCCCGGAGCTTCCAAAACAAGCAGCCGGAGGAGCAGTATGAGCATGGAAGA GACGGAGCACACTTGTTAGCGAATCCTCCCTGCACTGCATTCGCACAAACTGCTTCCTTTCTTGATTCGTAGATTTAATAACTTACCTGA AGGGGTTTTCTTGATAATTTTCCTTTAATATGAAATTTTTTTTCATGCTTTATCAATAGCCCAGGATATATTTTATTTTTAGAATTTTGT GAAACAGACTTGTATATTCTATTTTACAACTACAAATGCCTCCAAAGTATTGTACAAATAAGTGTGCAGTATCTGTGAACTGAATTCACC ACAGACTTTAGCTTTCTGAGCAAGAGGATTTTGCGTCAGAGAAATGTCTGTCCATTTTTATTCAGGGGAAACTTGATTTGAGATTTTTAT GCCTGTGACTTCCTTGGAAATCAAATGTAAAGTTTAATTGAAAGAATGTAAAGCAACCAAAAAGAAAAAAAAAAAGAAA >1695_1695_1_ACTG1-MITF_ACTG1_chr17_79478929_ENST00000575842_MITF_chr3_69986973_ENST00000314557_length(amino acids)=533AA_BP=130 MSPSFSGQVAMEEEIAALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWD DMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQVQTHLENPTKYHIQQAQRQQVKQYLSTTLANKHANQVLSLPCPNQPGDH VMPPVPGSSAPNSPMAMLTLNSNCEKEGFYKFEEQNRAESECPGMNTHSRASCMQMDDVIDDIISLESSYNEEILGLMDPALQMANTLPV SGNLIDLYGNQGLPPPGLTISNSCPANLPNIKRELTESEARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDMRWNKGTI LKASVDYIRKLQREQQRAKELENRQKKLEHANRHLLLRIQELEMQARAHGLSLIPSTGLCSPDLVNRIIKQEPVLENCSQDLLQHHADLT CTTTLDLTDGTITFNNNLGTGTEANQAYSVPTKMGSKLEDILMDDTLSPVGVTDPLLSSVSPGASKTSSRRSSMSMEETEHTC -------------------------------------------------------------- >1695_1695_2_ACTG1-MITF_ACTG1_chr17_79478929_ENST00000575842_MITF_chr3_69986973_ENST00000314589_length(transcript)=2398nt_BP=790nt CTCTCGCACTCTGTTCTTCCGCCGCTCCGCCGTCGCGTTTCTCTGCCGGTGAGCGCCCCGCCCCGGGGCCTGAGCTGGACGTCGCAGGCC TGCGCCCCCCGACCCCGGCTGGCCCCGCTTCCAGCTGCCGAGGCCTCGTCGCGCCTTCCCCGGGAACAAAAGGCGGGGTGGGCCGGGTCA GGCGGACGGGGCTGGGGGGGCGCCGGGGGTCCAGGGCGGGGCCCGGCCGCAGTGCAGACTTCCGAGCCGTGGACGTTACGTAAAAGGCCC GGCCTTCGGTTCCAGGCGGTTGCGATCTTGGAGGCCACGGCCGCTGGGGTTGGGGCAGGGCCGAGGCTTCCCCGCGGGAGGGCATTAGGT GGCTGTGGGGAGGGGACCGTGTTACAGACGCGCCCGCCTGAGTCCATCCTTTTCCGGGCAGGTCGCAATGGAAGAAGAGATCGCCGCGCT GGTCATTGACAATGGCTCCGGCATGTGCAAAGCTGGTTTTGCTGGGGACGACGCTCCCCGAGCCGTGTTTCCTTCCATCGTCGGGCGCCC CAGACACCAGGGCGTCATGGTGGGCATGGGCCAGAAGGACTCCTACGTGGGCGACGAGGCCCAGAGCAAGCGTGGCATCCTGACCCTGAA GTACCCCATTGAGCATGGCATCGTCACCAACTGGGACGACATGGAGAAGATCTGGCACCACACCTTCTACAACGAGCTGCGCGTGGCCCC GGAGGAGCACCCAGTGCTGCTGACCGAGGCCCCCCTGAACCCCAAGGCCAACAGAGAGAAGATGACTCAGGTGCAGACCCACCTCGAAAA CCCCACCAAGTACCACATACAGCAAGCCCAACGGCAGCAGGTAAAGCAGTACCTTTCTACCACTTTAGCAAATAAACATGCCAACCAAGT CCTGAGCTTGCCATGTCCAAACCAGCCTGGCGATCATGTCATGCCACCGGTGCCGGGGAGCAGCGCACCCAACAGCCCCATGGCTATGCT TACGCTTAACTCCAACTGTGAAAAAGAGGGATTTTATAAGTTTGAAGAGCAAAACAGGGCAGAGAGCGAGTGCCCAGGCATGAACACACA TTCACGAGCGTCCTGTATGCAGATGGATGATGTAATCGATGACATCATTAGCCTAGAATCAAGTTATAATGAGGAAATCTTGGGCTTGAT GGATCCTGCTTTGCAAATGGCAAATACGTTGCCTGTCTCGGGAAACTTGATTGATCTTTATGGAAACCAAGGTCTGCCCCCACCAGGCCT CACCATCAGCAACTCCTGTCCAGCCAACCTTCCCAACATAAAAAGGGAGCTCACAGAGTCTGAAGCAAGAGCACTGGCCAAAGAGAGGCA GAAAAAGGACAATCACAACCTGATTGAACGAAGAAGAAGATTTAACATAAATGACCGCATTAAAGAACTAGGTACTTTGATTCCCAAGTC AAATGATCCAGACATGCGCTGGAACAAGGGAACCATCTTAAAAGCATCCGTGGACTATATCCGAAAGTTGCAACGAGAACAGCAACGCGC AAAAGAACTTGAAAACCGACAGAAGAAACTGGAGCACGCCAACCGGCATTTGTTGCTCAGAATACAGGAACTTGAAATGCAGGCTCGAGC TCATGGACTTTCCCTTATTCCATCCACGGGTCTCTGCTCTCCAGATTTGGTGAATCGGATCATCAAGCAAGAACCCGTTCTTGAGAACTG CAGCCAAGACCTCCTTCAGCATCATGCAGACCTAACCTGTACAACAACTCTCGATCTCACGGATGGCACCATCACCTTCAACAACAACCT CGGAACTGGGACTGAGGCCAACCAAGCCTATAGTGTCCCCACAAAAATGGGATCCAAACTGGAAGACATCCTGATGGACGACACCCTTTC TCCCGTCGGTGTCACTGATCCACTCCTTTCCTCAGTGTCCCCCGGAGCTTCCAAAACAAGCAGCCGGAGGAGCAGTATGAGCATGGAAGA GACGGAGCACACTTGTTAGCGAATCCTCCCTGCACTGCATTCGCACAAACTGCTTCCTTTCTTGATTCGTAGATTTAATAACTTACCTGA AGGGGTTTTCTTGATAATTTTCCTTTAATATGAAATTTTTTTTCATGCTTTATCAATAGCCCAGGATATATTTTATTTTTAGAATTTTGT GAAACAGACTTGTATATTCTATTTTACAACTACAAATGCCTCCAAAGTATTGTACAAATAAGTGTGCAGTATCTGTGAACTGAATTCACC ACAGACTTTAGCTTTCTGAGCAAGAGGATTTTGCGTCAGAGAAATGTCTGTCCATTTTTATTCAGGGGAAACTTGATTTGAGATTTTTAT GCCTGTGACTTCCTTGGAAATCAAATGTAAAGTTTAATTGAAAGAATGTAAAGCAACC >1695_1695_2_ACTG1-MITF_ACTG1_chr17_79478929_ENST00000575842_MITF_chr3_69986973_ENST00000314589_length(amino acids)=533AA_BP=130 MSPSFSGQVAMEEEIAALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWD DMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQVQTHLENPTKYHIQQAQRQQVKQYLSTTLANKHANQVLSLPCPNQPGDH VMPPVPGSSAPNSPMAMLTLNSNCEKEGFYKFEEQNRAESECPGMNTHSRASCMQMDDVIDDIISLESSYNEEILGLMDPALQMANTLPV SGNLIDLYGNQGLPPPGLTISNSCPANLPNIKRELTESEARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDMRWNKGTI LKASVDYIRKLQREQQRAKELENRQKKLEHANRHLLLRIQELEMQARAHGLSLIPSTGLCSPDLVNRIIKQEPVLENCSQDLLQHHADLT CTTTLDLTDGTITFNNNLGTGTEANQAYSVPTKMGSKLEDILMDDTLSPVGVTDPLLSSVSPGASKTSSRRSSMSMEETEHTC -------------------------------------------------------------- >1695_1695_3_ACTG1-MITF_ACTG1_chr17_79478929_ENST00000575842_MITF_chr3_69986973_ENST00000328528_length(transcript)=5088nt_BP=790nt CTCTCGCACTCTGTTCTTCCGCCGCTCCGCCGTCGCGTTTCTCTGCCGGTGAGCGCCCCGCCCCGGGGCCTGAGCTGGACGTCGCAGGCC TGCGCCCCCCGACCCCGGCTGGCCCCGCTTCCAGCTGCCGAGGCCTCGTCGCGCCTTCCCCGGGAACAAAAGGCGGGGTGGGCCGGGTCA GGCGGACGGGGCTGGGGGGGCGCCGGGGGTCCAGGGCGGGGCCCGGCCGCAGTGCAGACTTCCGAGCCGTGGACGTTACGTAAAAGGCCC GGCCTTCGGTTCCAGGCGGTTGCGATCTTGGAGGCCACGGCCGCTGGGGTTGGGGCAGGGCCGAGGCTTCCCCGCGGGAGGGCATTAGGT GGCTGTGGGGAGGGGACCGTGTTACAGACGCGCCCGCCTGAGTCCATCCTTTTCCGGGCAGGTCGCAATGGAAGAAGAGATCGCCGCGCT GGTCATTGACAATGGCTCCGGCATGTGCAAAGCTGGTTTTGCTGGGGACGACGCTCCCCGAGCCGTGTTTCCTTCCATCGTCGGGCGCCC CAGACACCAGGGCGTCATGGTGGGCATGGGCCAGAAGGACTCCTACGTGGGCGACGAGGCCCAGAGCAAGCGTGGCATCCTGACCCTGAA GTACCCCATTGAGCATGGCATCGTCACCAACTGGGACGACATGGAGAAGATCTGGCACCACACCTTCTACAACGAGCTGCGCGTGGCCCC GGAGGAGCACCCAGTGCTGCTGACCGAGGCCCCCCTGAACCCCAAGGCCAACAGAGAGAAGATGACTCAGGTGCAGACCCACCTCGAAAA CCCCACCAAGTACCACATACAGCAAGCCCAACGGCAGCAGGTAAAGCAGTACCTTTCTACCACTTTAGCAAATAAACATGCCAACCAAGT CCTGAGCTTGCCATGTCCAAACCAGCCTGGCGATCATGTCATGCCACCGGTGCCGGGGAGCAGCGCACCCAACAGCCCCATGGCTATGCT TACGCTTAACTCCAACTGTGAAAAAGAGGGATTTTATAAGTTTGAAGAGCAAAACAGGGCAGAGAGCGAGTGCCCAGGCATGAACACACA TTCACGAGCGTCCTGTATGCAGATGGATGATGTAATCGATGACATCATTAGCCTAGAATCAAGTTATAATGAGGAAATCTTGGGCTTGAT GGATCCTGCTTTGCAAATGGCAAATACGTTGCCTGTCTCGGGAAACTTGATTGATCTTTATGGAAACCAAGGTCTGCCCCCACCAGGCCT CACCATCAGCAACTCCTGTCCAGCCAACCTTCCCAACATAAAAAGGGAGCTCACAGAGTCTGAAGCAAGAGCACTGGCCAAAGAGAGGCA GAAAAAGGACAATCACAACCTGATTGAACGAAGAAGAAGATTTAACATAAATGACCGCATTAAAGAACTAGGTACTTTGATTCCCAAGTC AAATGATCCAGACATGCGCTGGAACAAGGGAACCATCTTAAAAGCATCCGTGGACTATATCCGAAAGTTGCAACGAGAACAGCAACGCGC AAAAGAACTTGAAAACCGACAGAAGAAACTGGAGCACGCCAACCGGCATTTGTTGCTCAGAATACAGGAACTTGAAATGCAGGCTCGAGC TCATGGACTTTCCCTTATTCCATCCACGGGTCTCTGCTCTCCAGATTTGGTGAATCGGATCATCAAGCAAGAACCCGTTCTTGAGAACTG CAGCCAAGACCTCCTTCAGCATCATGCAGACCTAACCTGTACAACAACTCTCGATCTCACGGATGGCACCATCACCTTCAACAACAACCT CGGAACTGGGACTGAGGCCAACCAAGCCTATAGTGTCCCCACAAAAATGGGATCCAAACTGGAAGACATCCTGATGGACGACACCCTTTC TCCCGTCGGTGTCACTGATCCACTCCTTTCCTCAGTGTCCCCCGGAGCTTCCAAAACAAGCAGCCGGAGGAGCAGTATGAGCATGGAAGA GACGGAGCACACTTGTTAGCGAATCCTCCCTGCACTGCATTCGCACAAACTGCTTCCTTTCTTGATTCGTAGATTTAATAACTTACCTGA AGGGGTTTTCTTGATAATTTTCCTTTAATATGAAATTTTTTTTCATGCTTTATCAATAGCCCAGGATATATTTTATTTTTAGAATTTTGT GAAACAGACTTGTATATTCTATTTTACAACTACAAATGCCTCCAAAGTATTGTACAAATAAGTGTGCAGTATCTGTGAACTGAATTCACC ACAGACTTTAGCTTTCTGAGCAAGAGGATTTTGCGTCAGAGAAATGTCTGTCCATTTTTATTCAGGGGAAACTTGATTTGAGATTTTTAT GCCTGTGACTTCCTTGGAAATCAAATGTAAAGTTTAATTGAAAGAATGTAAAGCAACCAAAAAGAAAAAAAAAAAGAAAGAAAGAGGAAA AGAAATCCATACTAACCCTTTTCCATTTTATAAATGTATTGATTCATTGGTACTGCCTTAAAGATACAGTACCCCTCTAGCTTTGTTTAG TCTTTATACTGCAAACTATTTAAAGAAATATGTATTCTGTAAAAGAAAAAAAAAATGCGGCCTTTTCATGAGGATCGTCTGGTTAGAAAA CATAACTGATACCAACCGAAACTGAAGGGAGTTAGACCAAGGCTCTGAAATATAAAGTCTAATCTTGCTCTCTTTTATTCTGTGCTGTTA CAGTTTTCTTCATCAATGAGTGTGATCCAGTTTTTCATAAGATATTTTATTTTGAAATGGAAATTAATGTCCTCTCAAAGTAAAATATTG AGGAGCACTGAAAGTATGTTTTACTTTTTTTTTATTTTATTTTTGCTTTTGATAAGAAAACCGAACTGGGCATATTTCTAATTGGCTTTA CTATTTTTATTTTTAAATTATGTTTTACTGTTCATTTGATTTGTACAGATTCTTTATTATCATTGTTCTTTTCAATATATTTGTATTAAT TTGTAAGAATATGCATCTTAAAATGGCAAGTTTTCCATATTTTTACAACTCACTGGTGGTTTTCCGCATTCTTTGTACACCCATGAAAGA AAACTTTTATGCAAGGTCTTGCATTTAAAAGACAGCTTTGCGAATATTTTGTAAATTACAGTCTCACTCAGAACTGTTTTTGGACACATT TAAGGTGTAGTATTAATAGGTTAAAACCAGGCTTTCTAGAAAGAATAAACTTACATATTTATTTTTAGGACATGAAAATAGCAATATTCT TGGAGATTGATAACCATAGCATTAATACGCCCATTATGGTCATTTAAATTGGGGTTTATTTCAGCAAACTTGTTGAATTTATTTTTAAGA AAGAAATACTGTATTGGGAAGTTACTGTTACTTGATAACAATGTTTTAACAAGAAGCAATGTTATAAAGTTAGTTTCAGTGCATTATCTA CTTGTGTAGTCCTATGCAATAACAGTAGTGTTACATGTATCAAGCCTAGATGTTTTATACAGATGCCATATAGTGTTATGAGCCAGGCTG TTGAATGGAATTTCTCAGTAGCAGCCTACAACTGAATAGCAAGTGGCATAAAGCATATCCATTCAGAATGAAGTGCCTTAAATATAGCAG TAGTCTTTTTTGGACTAGCACTGACTGAACTGTAATGTAGGGGAAAGTTTCATGATGGTATCTATAGTCAAGACGAACATGTAGCATGGT GCCTATGTAGACAATATAAGAGCTTCCAATTTTCCTTCAGATATTTTTAATATTAAATATATTTTAGTGACAGAGTGCCAACTTCTTTCA TCAGGAAACCTTATTCAGGAGGGTTTTTAAAAAGTGTTTAAATGTCAAATGTGAATTGGTGATGGGTGATGGAGGGTTCAGAGAGGAGTG ATCGTCAGATGTGTGAATGGACGGTTTAGGTGAAAATAATCAACTGCATAGTTCCCATGCACGCTGGGCAATGAGAATCCTTGGAAACAT TGGTGATGCTATCAGTTTTATAGCTTTATTTCTTAAGGGGGTAGGGAAAATTAGTTCCCATTCTTTCAACCCCCTTAACTGTATAGCTCT TTTCCTAGAATAGTGACGCAAATCTGCATGAACAGCTAATTGTACCATAGTGTTCATTGATACAATCATAGCATTGTCTATTTTTCTCTT CATATTTATATGGGGGGGAGGGCGCTGGATGCAAAAGTTGAAGATCGTGATGCTATGATGTTAGTTTTCCTTAGCTGATTTTGAGGGTTT TTAAAAATAAAGCAAGGTTGACTAACCTACGGCCACGGGAACAGGACCATGGTTAAGCAACCATATAGAAAGCTTTGTTGAAAGAAAGTA TGGCATCTTGTACCACTGCCCTGACTGTCACAACTCCTAACCTTGCCATTGCCTGCCTCCCCCTCCCCTTCTCCTTAAGAGACAATTTCT GCAGGTGGCAGGTGAGCAAGCCCAGGAGAATGCTGCAATCTTGGGGGTGGTTTTATTTATTTCTTTTTTGCCAAATAGAGTGTGGATTCA TTTCAGGGGCTAGCTAAGCCAAGAGGCAGTGGTTTGGGCTTGTTGTTTGTAACAAGAAAATGATCCACACCACTCCCCCGATTCCCGGGT GCAGAATTGTAACTCGGGGTTGGGCCTCTATATGGAGTGACCAAAATGCCAAAATTGTCCATCTGCCTCTGAGTAGGGCAATGGAAATAC CAAACCTTCTGACTTTGCCAAAAAGCATACAAGCAACCTGGTCATACATAGGATGACAAAATTCTTTCTGGTTGTTTTTAAACAATAAAG CAATAAGAACAAATACAATACATAGGAAGTTAAAAGCACAAAGGAATGAACTTATTAATATTTTTGAAAAATGCACTGGGAAAAAGTTGA TGTCAATAACAGTATAAAACAGCCCTATTTCTTGATAAAAAATGACAAATGACTGTCTCTTGCGGATGCTTGGTACTGTAATGTTAATAA TAGTCACCTGCTGTTGGATGCAGCAATAATTTCTGTATGGTCCATAGCACTGTATATTATGGATCGATATTAATGTATCCAATGAAATAA TCGACTTGTTCTTGATAGCCTCATTAAAGCATTTGGTTTTTCACATAG >1695_1695_3_ACTG1-MITF_ACTG1_chr17_79478929_ENST00000575842_MITF_chr3_69986973_ENST00000328528_length(amino acids)=533AA_BP=130 MSPSFSGQVAMEEEIAALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWD DMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQVQTHLENPTKYHIQQAQRQQVKQYLSTTLANKHANQVLSLPCPNQPGDH VMPPVPGSSAPNSPMAMLTLNSNCEKEGFYKFEEQNRAESECPGMNTHSRASCMQMDDVIDDIISLESSYNEEILGLMDPALQMANTLPV SGNLIDLYGNQGLPPPGLTISNSCPANLPNIKRELTESEARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDMRWNKGTI LKASVDYIRKLQREQQRAKELENRQKKLEHANRHLLLRIQELEMQARAHGLSLIPSTGLCSPDLVNRIIKQEPVLENCSQDLLQHHADLT CTTTLDLTDGTITFNNNLGTGTEANQAYSVPTKMGSKLEDILMDDTLSPVGVTDPLLSSVSPGASKTSSRRSSMSMEETEHTC -------------------------------------------------------------- >1695_1695_4_ACTG1-MITF_ACTG1_chr17_79478929_ENST00000575842_MITF_chr3_69986973_ENST00000352241_length(transcript)=5087nt_BP=790nt CTCTCGCACTCTGTTCTTCCGCCGCTCCGCCGTCGCGTTTCTCTGCCGGTGAGCGCCCCGCCCCGGGGCCTGAGCTGGACGTCGCAGGCC TGCGCCCCCCGACCCCGGCTGGCCCCGCTTCCAGCTGCCGAGGCCTCGTCGCGCCTTCCCCGGGAACAAAAGGCGGGGTGGGCCGGGTCA GGCGGACGGGGCTGGGGGGGCGCCGGGGGTCCAGGGCGGGGCCCGGCCGCAGTGCAGACTTCCGAGCCGTGGACGTTACGTAAAAGGCCC GGCCTTCGGTTCCAGGCGGTTGCGATCTTGGAGGCCACGGCCGCTGGGGTTGGGGCAGGGCCGAGGCTTCCCCGCGGGAGGGCATTAGGT GGCTGTGGGGAGGGGACCGTGTTACAGACGCGCCCGCCTGAGTCCATCCTTTTCCGGGCAGGTCGCAATGGAAGAAGAGATCGCCGCGCT GGTCATTGACAATGGCTCCGGCATGTGCAAAGCTGGTTTTGCTGGGGACGACGCTCCCCGAGCCGTGTTTCCTTCCATCGTCGGGCGCCC CAGACACCAGGGCGTCATGGTGGGCATGGGCCAGAAGGACTCCTACGTGGGCGACGAGGCCCAGAGCAAGCGTGGCATCCTGACCCTGAA GTACCCCATTGAGCATGGCATCGTCACCAACTGGGACGACATGGAGAAGATCTGGCACCACACCTTCTACAACGAGCTGCGCGTGGCCCC GGAGGAGCACCCAGTGCTGCTGACCGAGGCCCCCCTGAACCCCAAGGCCAACAGAGAGAAGATGACTCAGGTGCAGACCCACCTCGAAAA CCCCACCAAGTACCACATACAGCAAGCCCAACGGCAGCAGGTAAAGCAGTACCTTTCTACCACTTTAGCAAATAAACATGCCAACCAAGT CCTGAGCTTGCCATGTCCAAACCAGCCTGGCGATCATGTCATGCCACCGGTGCCGGGGAGCAGCGCACCCAACAGCCCCATGGCTATGCT TACGCTTAACTCCAACTGTGAAAAAGAGGGATTTTATAAGTTTGAAGAGCAAAACAGGGCAGAGAGCGAGTGCCCAGGCATGAACACACA TTCACGAGCGTCCTGTATGCAGATGGATGATGTAATCGATGACATCATTAGCCTAGAATCAAGTTATAATGAGGAAATCTTGGGCTTGAT GGATCCTGCTTTGCAAATGGCAAATACGTTGCCTGTCTCGGGAAACTTGATTGATCTTTATGGAAACCAAGGTCTGCCCCCACCAGGCCT CACCATCAGCAACTCCTGTCCAGCCAACCTTCCCAACATAAAAAGGGAGCTCACAGAGTCTGAAGCAAGAGCACTGGCCAAAGAGAGGCA GAAAAAGGACAATCACAACCTGATTGAACGAAGAAGAAGATTTAACATAAATGACCGCATTAAAGAACTAGGTACTTTGATTCCCAAGTC AAATGATCCAGACATGCGCTGGAACAAGGGAACCATCTTAAAAGCATCCGTGGACTATATCCGAAAGTTGCAACGAGAACAGCAACGCGC AAAAGAACTTGAAAACCGACAGAAGAAACTGGAGCACGCCAACCGGCATTTGTTGCTCAGAATACAGGAACTTGAAATGCAGGCTCGAGC TCATGGACTTTCCCTTATTCCATCCACGGGTCTCTGCTCTCCAGATTTGGTGAATCGGATCATCAAGCAAGAACCCGTTCTTGAGAACTG CAGCCAAGACCTCCTTCAGCATCATGCAGACCTAACCTGTACAACAACTCTCGATCTCACGGATGGCACCATCACCTTCAACAACAACCT CGGAACTGGGACTGAGGCCAACCAAGCCTATAGTGTCCCCACAAAAATGGGATCCAAACTGGAAGACATCCTGATGGACGACACCCTTTC TCCCGTCGGTGTCACTGATCCACTCCTTTCCTCAGTGTCCCCCGGAGCTTCCAAAACAAGCAGCCGGAGGAGCAGTATGAGCATGGAAGA GACGGAGCACACTTGTTAGCGAATCCTCCCTGCACTGCATTCGCACAAACTGCTTCCTTTCTTGATTCGTAGATTTAATAACTTACCTGA AGGGGTTTTCTTGATAATTTTCCTTTAATATGAAATTTTTTTTCATGCTTTATCAATAGCCCAGGATATATTTTATTTTTAGAATTTTGT GAAACAGACTTGTATATTCTATTTTACAACTACAAATGCCTCCAAAGTATTGTACAAATAAGTGTGCAGTATCTGTGAACTGAATTCACC ACAGACTTTAGCTTTCTGAGCAAGAGGATTTTGCGTCAGAGAAATGTCTGTCCATTTTTATTCAGGGGAAACTTGATTTGAGATTTTTAT GCCTGTGACTTCCTTGGAAATCAAATGTAAAGTTTAATTGAAAGAATGTAAAGCAACCAAAAAGAAAAAAAAAAAGAAAGAAAGAGGAAA AGAAATCCATACTAACCCTTTTCCATTTTATAAATGTATTGATTCATTGGTACTGCCTTAAAGATACAGTACCCCTCTAGCTTTGTTTAG TCTTTATACTGCAAACTATTTAAAGAAATATGTATTCTGTAAAAGAAAAAAAAAATGCGGCCTTTTCATGAGGATCGTCTGGTTAGAAAA CATAACTGATACCAACCGAAACTGAAGGGAGTTAGACCAAGGCTCTGAAATATAAAGTCTAATCTTGCTCTCTTTTATTCTGTGCTGTTA CAGTTTTCTTCATCAATGAGTGTGATCCAGTTTTTCATAAGATATTTTATTTTGAAATGGAAATTAATGTCCTCTCAAAGTAAAATATTG AGGAGCACTGAAAGTATGTTTTACTTTTTTTTTATTTTATTTTTGCTTTTGATAAGAAAACCGAACTGGGCATATTTCTAATTGGCTTTA CTATTTTTATTTTTAAATTATGTTTTACTGTTCATTTGATTTGTACAGATTCTTTATTATCATTGTTCTTTTCAATATATTTGTATTAAT TTGTAAGAATATGCATCTTAAAATGGCAAGTTTTCCATATTTTTACAACTCACTGGTGGTTTTCCGCATTCTTTGTACACCCATGAAAGA AAACTTTTATGCAAGGTCTTGCATTTAAAAGACAGCTTTGCGAATATTTTGTAAATTACAGTCTCACTCAGAACTGTTTTTGGACACATT TAAGGTGTAGTATTAATAGGTTAAAACCAGGCTTTCTAGAAAGAATAAACTTACATATTTATTTTTAGGACATGAAAATAGCAATATTCT TGGAGATTGATAACCATAGCATTAATACGCCCATTATGGTCATTTAAATTGGGGTTTATTTCAGCAAACTTGTTGAATTTATTTTTAAGA AAGAAATACTGTATTGGGAAGTTACTGTTACTTGATAACAATGTTTTAACAAGAAGCAATGTTATAAAGTTAGTTTCAGTGCATTATCTA CTTGTGTAGTCCTATGCAATAACAGTAGTGTTACATGTATCAAGCCTAGATGTTTTATACAGATGCCATATAGTGTTATGAGCCAGGCTG TTGAATGGAATTTCTCAGTAGCAGCCTACAACTGAATAGCAAGTGGCATAAAGCATATCCATTCAGAATGAAGTGCCTTAAATATAGCAG TAGTCTTTTTTGGACTAGCACTGACTGAACTGTAATGTAGGGGAAAGTTTCATGATGGTATCTATAGTCAAGACGAACATGTAGCATGGT GCCTATGTAGACAATATAAGAGCTTCCAATTTTCCTTCAGATATTTTTAATATTAAATATATTTTAGTGACAGAGTGCCAACTTCTTTCA TCAGGAAACCTTATTCAGGAGGGTTTTTAAAAAGTGTTTAAATGTCAAATGTGAATTGGTGATGGGTGATGGAGGGTTCAGAGAGGAGTG ATCGTCAGATGTGTGAATGGACGGTTTAGGTGAAAATAATCAACTGCATAGTTCCCATGCACGCTGGGCAATGAGAATCCTTGGAAACAT TGGTGATGCTATCAGTTTTATAGCTTTATTTCTTAAGGGGGTAGGGAAAATTAGTTCCCATTCTTTCAACCCCCTTAACTGTATAGCTCT TTTCCTAGAATAGTGACGCAAATCTGCATGAACAGCTAATTGTACCATAGTGTTCATTGATACAATCATAGCATTGTCTATTTTTCTCTT CATATTTATATGGGGGGGAGGGCGCTGGATGCAAAAGTTGAAGATCGTGATGCTATGATGTTAGTTTTCCTTAGCTGATTTTGAGGGTTT TTAAAAATAAAGCAAGGTTGACTAACCTACGGCCACGGGAACAGGACCATGGTTAAGCAACCATATAGAAAGCTTTGTTGAAAGAAAGTA TGGCATCTTGTACCACTGCCCTGACTGTCACAACTCCTAACCTTGCCATTGCCTGCCTCCCCCTCCCCTTCTCCTTAAGAGACAATTTCT GCAGGTGGCAGGTGAGCAAGCCCAGGAGAATGCTGCAATCTTGGGGGTGGTTTTATTTATTTCTTTTTTGCCAAATAGAGTGTGGATTCA TTTCAGGGGCTAGCTAAGCCAAGAGGCAGTGGTTTGGGCTTGTTGTTTGTAACAAGAAAATGATCCACACCACTCCCCCGATTCCCGGGT GCAGAATTGTAACTCGGGGTTGGGCCTCTATATGGAGTGACCAAAATGCCAAAATTGTCCATCTGCCTCTGAGTAGGGCAATGGAAATAC CAAACCTTCTGACTTTGCCAAAAAGCATACAAGCAACCTGGTCATACATAGGATGACAAAATTCTTTCTGGTTGTTTTTAAACAATAAAG CAATAAGAACAAATACAATACATAGGAAGTTAAAAGCACAAAGGAATGAACTTATTAATATTTTTGAAAAATGCACTGGGAAAAAGTTGA TGTCAATAACAGTATAAAACAGCCCTATTTCTTGATAAAAAATGACAAATGACTGTCTCTTGCGGATGCTTGGTACTGTAATGTTAATAA TAGTCACCTGCTGTTGGATGCAGCAATAATTTCTGTATGGTCCATAGCACTGTATATTATGGATCGATATTAATGTATCCAATGAAATAA TCGACTTGTTCTTGATAGCCTCATTAAAGCATTTGGTTTTTCACATA >1695_1695_4_ACTG1-MITF_ACTG1_chr17_79478929_ENST00000575842_MITF_chr3_69986973_ENST00000352241_length(amino acids)=533AA_BP=130 MSPSFSGQVAMEEEIAALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWD DMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQVQTHLENPTKYHIQQAQRQQVKQYLSTTLANKHANQVLSLPCPNQPGDH VMPPVPGSSAPNSPMAMLTLNSNCEKEGFYKFEEQNRAESECPGMNTHSRASCMQMDDVIDDIISLESSYNEEILGLMDPALQMANTLPV SGNLIDLYGNQGLPPPGLTISNSCPANLPNIKRELTESEARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDMRWNKGTI LKASVDYIRKLQREQQRAKELENRQKKLEHANRHLLLRIQELEMQARAHGLSLIPSTGLCSPDLVNRIIKQEPVLENCSQDLLQHHADLT CTTTLDLTDGTITFNNNLGTGTEANQAYSVPTKMGSKLEDILMDDTLSPVGVTDPLLSSVSPGASKTSSRRSSMSMEETEHTC -------------------------------------------------------------- >1695_1695_5_ACTG1-MITF_ACTG1_chr17_79478929_ENST00000575842_MITF_chr3_69986973_ENST00000394351_length(transcript)=2593nt_BP=790nt CTCTCGCACTCTGTTCTTCCGCCGCTCCGCCGTCGCGTTTCTCTGCCGGTGAGCGCCCCGCCCCGGGGCCTGAGCTGGACGTCGCAGGCC TGCGCCCCCCGACCCCGGCTGGCCCCGCTTCCAGCTGCCGAGGCCTCGTCGCGCCTTCCCCGGGAACAAAAGGCGGGGTGGGCCGGGTCA GGCGGACGGGGCTGGGGGGGCGCCGGGGGTCCAGGGCGGGGCCCGGCCGCAGTGCAGACTTCCGAGCCGTGGACGTTACGTAAAAGGCCC GGCCTTCGGTTCCAGGCGGTTGCGATCTTGGAGGCCACGGCCGCTGGGGTTGGGGCAGGGCCGAGGCTTCCCCGCGGGAGGGCATTAGGT GGCTGTGGGGAGGGGACCGTGTTACAGACGCGCCCGCCTGAGTCCATCCTTTTCCGGGCAGGTCGCAATGGAAGAAGAGATCGCCGCGCT GGTCATTGACAATGGCTCCGGCATGTGCAAAGCTGGTTTTGCTGGGGACGACGCTCCCCGAGCCGTGTTTCCTTCCATCGTCGGGCGCCC CAGACACCAGGGCGTCATGGTGGGCATGGGCCAGAAGGACTCCTACGTGGGCGACGAGGCCCAGAGCAAGCGTGGCATCCTGACCCTGAA GTACCCCATTGAGCATGGCATCGTCACCAACTGGGACGACATGGAGAAGATCTGGCACCACACCTTCTACAACGAGCTGCGCGTGGCCCC GGAGGAGCACCCAGTGCTGCTGACCGAGGCCCCCCTGAACCCCAAGGCCAACAGAGAGAAGATGACTCAGGTGCAGACCCACCTCGAAAA CCCCACCAAGTACCACATACAGCAAGCCCAACGGCAGCAGGTAAAGCAGTACCTTTCTACCACTTTAGCAAATAAACATGCCAACCAAGT CCTGAGCTTGCCATGTCCAAACCAGCCTGGCGATCATGTCATGCCACCGGTGCCGGGGAGCAGCGCACCCAACAGCCCCATGGCTATGCT TACGCTTAACTCCAACTGTGAAAAAGAGGGATTTTATAAGTTTGAAGAGCAAAACAGGGCAGAGAGCGAGTGCCCAGGCATGAACACACA TTCACGAGCGTCCTGTATGCAGATGGATGATGTAATCGATGACATCATTAGCCTAGAATCAAGTTATAATGAGGAAATCTTGGGCTTGAT GGATCCTGCTTTGCAAATGGCAAATACGTTGCCTGTCTCGGGAAACTTGATTGATCTTTATGGAAACCAAGGTCTGCCCCCACCAGGCCT CACCATCAGCAACTCCTGTCCAGCCAACCTTCCCAACATAAAAAGGGAGCTCACAGCGTGTATTTTTCCCACAGAGTCTGAAGCAAGAGC ACTGGCCAAAGAGAGGCAGAAAAAGGACAATCACAACCTGATTGAACGAAGAAGAAGATTTAACATAAATGACCGCATTAAAGAACTAGG TACTTTGATTCCCAAGTCAAATGATCCAGACATGCGCTGGAACAAGGGAACCATCTTAAAAGCATCCGTGGACTATATCCGAAAGTTGCA ACGAGAACAGCAACGCGCAAAAGAACTTGAAAACCGACAGAAGAAACTGGAGCACGCCAACCGGCATTTGTTGCTCAGAATACAGGAACT TGAAATGCAGGCTCGAGCTCATGGACTTTCCCTTATTCCATCCACGGGTCTCTGCTCTCCAGATTTGGTGAATCGGATCATCAAGCAAGA ACCCGTTCTTGAGAACTGCAGCCAAGACCTCCTTCAGCATCATGCAGACCTAACCTGTACAACAACTCTCGATCTCACGGATGGCACCAT CACCTTCAACAACAACCTCGGAACTGGGACTGAGGCCAACCAAGCCTATAGTGTCCCCACAAAAATGGGATCCAAACTGGAAGACATCCT GATGGACGACACCCTTTCTCCCGTCGGTGTCACTGATCCACTCCTTTCCTCAGTGTCCCCCGGAGCTTCCAAAACAAGCAGCCGGAGGAG CAGTATGAGCATGGAAGAGACGGAGCACACTTGTTAGCGAATCCTCCCTGCACTGCATTCGCACAAACTGCTTCCTTTCTTGATTCGTAG ATTTAATAACTTACCTGAAGGGGTTTTCTTGATAATTTTCCTTTAATATGAAATTTTTTTTCATGCTTTATCAATAGCCCAGGATATATT TTATTTTTAGAATTTTGTGAAACAGACTTGTATATTCTATTTTACAACTACAAATGCCTCCAAAGTATTGTACAAATAAGTGTGCAGTAT CTGTGAACTGAATTCACCACAGACTTTAGCTTTCTGAGCAAGAGGATTTTGCGTCAGAGAAATGTCTGTCCATTTTTATTCAGGGGAAAC TTGATTTGAGATTTTTATGCCTGTGACTTCCTTGGAAATCAAATGTAAAGTTTAATTGAAAGAATGTAAAGCAACCAAAAAGAAAAAAAA AAAGAAAGAAAGAGGAAAAGAAATCCATACTAACCCTTTTCCATTTTATAAATGTATTGATTCATTGGTACTGCCTTAAAGATACAGTAC CCCTCTAGCTTTGTTTAGTCTTTATACTGCAAACTATTTAAAGAAATATGTATTCTGTAAAAGAAAAAAAAAA >1695_1695_5_ACTG1-MITF_ACTG1_chr17_79478929_ENST00000575842_MITF_chr3_69986973_ENST00000394351_length(amino acids)=539AA_BP=130 MSPSFSGQVAMEEEIAALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWD DMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQVQTHLENPTKYHIQQAQRQQVKQYLSTTLANKHANQVLSLPCPNQPGDH VMPPVPGSSAPNSPMAMLTLNSNCEKEGFYKFEEQNRAESECPGMNTHSRASCMQMDDVIDDIISLESSYNEEILGLMDPALQMANTLPV SGNLIDLYGNQGLPPPGLTISNSCPANLPNIKRELTACIFPTESEARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDMR WNKGTILKASVDYIRKLQREQQRAKELENRQKKLEHANRHLLLRIQELEMQARAHGLSLIPSTGLCSPDLVNRIIKQEPVLENCSQDLLQ HHADLTCTTTLDLTDGTITFNNNLGTGTEANQAYSVPTKMGSKLEDILMDDTLSPVGVTDPLLSSVSPGASKTSSRRSSMSMEETEHTC -------------------------------------------------------------- >1695_1695_6_ACTG1-MITF_ACTG1_chr17_79478929_ENST00000575842_MITF_chr3_69986973_ENST00000394355_length(transcript)=5084nt_BP=790nt CTCTCGCACTCTGTTCTTCCGCCGCTCCGCCGTCGCGTTTCTCTGCCGGTGAGCGCCCCGCCCCGGGGCCTGAGCTGGACGTCGCAGGCC TGCGCCCCCCGACCCCGGCTGGCCCCGCTTCCAGCTGCCGAGGCCTCGTCGCGCCTTCCCCGGGAACAAAAGGCGGGGTGGGCCGGGTCA GGCGGACGGGGCTGGGGGGGCGCCGGGGGTCCAGGGCGGGGCCCGGCCGCAGTGCAGACTTCCGAGCCGTGGACGTTACGTAAAAGGCCC GGCCTTCGGTTCCAGGCGGTTGCGATCTTGGAGGCCACGGCCGCTGGGGTTGGGGCAGGGCCGAGGCTTCCCCGCGGGAGGGCATTAGGT GGCTGTGGGGAGGGGACCGTGTTACAGACGCGCCCGCCTGAGTCCATCCTTTTCCGGGCAGGTCGCAATGGAAGAAGAGATCGCCGCGCT GGTCATTGACAATGGCTCCGGCATGTGCAAAGCTGGTTTTGCTGGGGACGACGCTCCCCGAGCCGTGTTTCCTTCCATCGTCGGGCGCCC CAGACACCAGGGCGTCATGGTGGGCATGGGCCAGAAGGACTCCTACGTGGGCGACGAGGCCCAGAGCAAGCGTGGCATCCTGACCCTGAA GTACCCCATTGAGCATGGCATCGTCACCAACTGGGACGACATGGAGAAGATCTGGCACCACACCTTCTACAACGAGCTGCGCGTGGCCCC GGAGGAGCACCCAGTGCTGCTGACCGAGGCCCCCCTGAACCCCAAGGCCAACAGAGAGAAGATGACTCAGGTGCAGACCCACCTCGAAAA CCCCACCAAGTACCACATACAGCAAGCCCAACGGCAGCAGGTAAAGCAGTACCTTTCTACCACTTTAGCAAATAAACATGCCAACCAAGT CCTGAGCTTGCCATGTCCAAACCAGCCTGGCGATCATGTCATGCCACCGGTGCCGGGGAGCAGCGCACCCAACAGCCCCATGGCTATGCT TACGCTTAACTCCAACTGTGAAAAAGAGGGATTTTATAAGTTTGAAGAGCAAAACAGGGCAGAGAGCGAGTGCCCAGGCATGAACACACA TTCACGAGCGTCCTGTATGCAGATGGATGATGTAATCGATGACATCATTAGCCTAGAATCAAGTTATAATGAGGAAATCTTGGGCTTGAT GGATCCTGCTTTGCAAATGGCAAATACGTTGCCTGTCTCGGGAAACTTGATTGATCTTTATGGAAACCAAGGTCTGCCCCCACCAGGCCT CACCATCAGCAACTCCTGTCCAGCCAACCTTCCCAACATAAAAAGGGAGCTCACAGAGTCTGAAGCAAGAGCACTGGCCAAAGAGAGGCA GAAAAAGGACAATCACAACCTGATTGAACGAAGAAGAAGATTTAACATAAATGACCGCATTAAAGAACTAGGTACTTTGATTCCCAAGTC AAATGATCCAGACATGCGCTGGAACAAGGGAACCATCTTAAAAGCATCCGTGGACTATATCCGAAAGTTGCAACGAGAACAGCAACGCGC AAAAGAACTTGAAAACCGACAGAAGAAACTGGAGCACGCCAACCGGCATTTGTTGCTCAGAATACAGGAACTTGAAATGCAGGCTCGAGC TCATGGACTTTCCCTTATTCCATCCACGGGTCTCTGCTCTCCAGATTTGGTGAATCGGATCATCAAGCAAGAACCCGTTCTTGAGAACTG CAGCCAAGACCTCCTTCAGCATCATGCAGACCTAACCTGTACAACAACTCTCGATCTCACGGATGGCACCATCACCTTCAACAACAACCT CGGAACTGGGACTGAGGCCAACCAAGCCTATAGTGTCCCCACAAAAATGGGATCCAAACTGGAAGACATCCTGATGGACGACACCCTTTC TCCCGTCGGTGTCACTGATCCACTCCTTTCCTCAGTGTCCCCCGGAGCTTCCAAAACAAGCAGCCGGAGGAGCAGTATGAGCATGGAAGA GACGGAGCACACTTGTTAGCGAATCCTCCCTGCACTGCATTCGCACAAACTGCTTCCTTTCTTGATTCGTAGATTTAATAACTTACCTGA AGGGGTTTTCTTGATAATTTTCCTTTAATATGAAATTTTTTTTCATGCTTTATCAATAGCCCAGGATATATTTTATTTTTAGAATTTTGT GAAACAGACTTGTATATTCTATTTTACAACTACAAATGCCTCCAAAGTATTGTACAAATAAGTGTGCAGTATCTGTGAACTGAATTCACC ACAGACTTTAGCTTTCTGAGCAAGAGGATTTTGCGTCAGAGAAATGTCTGTCCATTTTTATTCAGGGGAAACTTGATTTGAGATTTTTAT GCCTGTGACTTCCTTGGAAATCAAATGTAAAGTTTAATTGAAAGAATGTAAAGCAACCAAAAAGAAAAAAAAAAAGAAAGAAAGAGGAAA AGAAATCCATACTAACCCTTTTCCATTTTATAAATGTATTGATTCATTGGTACTGCCTTAAAGATACAGTACCCCTCTAGCTTTGTTTAG TCTTTATACTGCAAACTATTTAAAGAAATATGTATTCTGTAAAAGAAAAAAAAAATGCGGCCTTTTCATGAGGATCGTCTGGTTAGAAAA CATAACTGATACCAACCGAAACTGAAGGGAGTTAGACCAAGGCTCTGAAATATAAAGTCTAATCTTGCTCTCTTTTATTCTGTGCTGTTA CAGTTTTCTTCATCAATGAGTGTGATCCAGTTTTTCATAAGATATTTTATTTTGAAATGGAAATTAATGTCCTCTCAAAGTAAAATATTG AGGAGCACTGAAAGTATGTTTTACTTTTTTTTTATTTTATTTTTGCTTTTGATAAGAAAACCGAACTGGGCATATTTCTAATTGGCTTTA CTATTTTTATTTTTAAATTATGTTTTACTGTTCATTTGATTTGTACAGATTCTTTATTATCATTGTTCTTTTCAATATATTTGTATTAAT TTGTAAGAATATGCATCTTAAAATGGCAAGTTTTCCATATTTTTACAACTCACTGGTGGTTTTCCGCATTCTTTGTACACCCATGAAAGA AAACTTTTATGCAAGGTCTTGCATTTAAAAGACAGCTTTGCGAATATTTTGTAAATTACAGTCTCACTCAGAACTGTTTTTGGACACATT TAAGGTGTAGTATTAATAGGTTAAAACCAGGCTTTCTAGAAAGAATAAACTTACATATTTATTTTTAGGACATGAAAATAGCAATATTCT TGGAGATTGATAACCATAGCATTAATACGCCCATTATGGTCATTTAAATTGGGGTTTATTTCAGCAAACTTGTTGAATTTATTTTTAAGA AAGAAATACTGTATTGGGAAGTTACTGTTACTTGATAACAATGTTTTAACAAGAAGCAATGTTATAAAGTTAGTTTCAGTGCATTATCTA CTTGTGTAGTCCTATGCAATAACAGTAGTGTTACATGTATCAAGCCTAGATGTTTTATACAGATGCCATATAGTGTTATGAGCCAGGCTG TTGAATGGAATTTCTCAGTAGCAGCCTACAACTGAATAGCAAGTGGCATAAAGCATATCCATTCAGAATGAAGTGCCTTAAATATAGCAG TAGTCTTTTTTGGACTAGCACTGACTGAACTGTAATGTAGGGGAAAGTTTCATGATGGTATCTATAGTCAAGACGAACATGTAGCATGGT GCCTATGTAGACAATATAAGAGCTTCCAATTTTCCTTCAGATATTTTTAATATTAAATATATTTTAGTGACAGAGTGCCAACTTCTTTCA TCAGGAAACCTTATTCAGGAGGGTTTTTAAAAAGTGTTTAAATGTCAAATGTGAATTGGTGATGGGTGATGGAGGGTTCAGAGAGGAGTG ATCGTCAGATGTGTGAATGGACGGTTTAGGTGAAAATAATCAACTGCATAGTTCCCATGCACGCTGGGCAATGAGAATCCTTGGAAACAT TGGTGATGCTATCAGTTTTATAGCTTTATTTCTTAAGGGGGTAGGGAAAATTAGTTCCCATTCTTTCAACCCCCTTAACTGTATAGCTCT TTTCCTAGAATAGTGACGCAAATCTGCATGAACAGCTAATTGTACCATAGTGTTCATTGATACAATCATAGCATTGTCTATTTTTCTCTT CATATTTATATGGGGGGGAGGGCGCTGGATGCAAAAGTTGAAGATCGTGATGCTATGATGTTAGTTTTCCTTAGCTGATTTTGAGGGTTT TTAAAAATAAAGCAAGGTTGACTAACCTACGGCCACGGGAACAGGACCATGGTTAAGCAACCATATAGAAAGCTTTGTTGAAAGAAAGTA TGGCATCTTGTACCACTGCCCTGACTGTCACAACTCCTAACCTTGCCATTGCCTGCCTCCCCCTCCCCTTCTCCTTAAGAGACAATTTCT GCAGGTGGCAGGTGAGCAAGCCCAGGAGAATGCTGCAATCTTGGGGGTGGTTTTATTTATTTCTTTTTTGCCAAATAGAGTGTGGATTCA TTTCAGGGGCTAGCTAAGCCAAGAGGCAGTGGTTTGGGCTTGTTGTTTGTAACAAGAAAATGATCCACACCACTCCCCCGATTCCCGGGT GCAGAATTGTAACTCGGGGTTGGGCCTCTATATGGAGTGACCAAAATGCCAAAATTGTCCATCTGCCTCTGAGTAGGGCAATGGAAATAC CAAACCTTCTGACTTTGCCAAAAAGCATACAAGCAACCTGGTCATACATAGGATGACAAAATTCTTTCTGGTTGTTTTTAAACAATAAAG CAATAAGAACAAATACAATACATAGGAAGTTAAAAGCACAAAGGAATGAACTTATTAATATTTTTGAAAAATGCACTGGGAAAAAGTTGA TGTCAATAACAGTATAAAACAGCCCTATTTCTTGATAAAAAATGACAAATGACTGTCTCTTGCGGATGCTTGGTACTGTAATGTTAATAA TAGTCACCTGCTGTTGGATGCAGCAATAATTTCTGTATGGTCCATAGCACTGTATATTATGGATCGATATTAATGTATCCAATGAAATAA TCGACTTGTTCTTGATAGCCTCATTAAAGCATTTGGTTTTTCAC >1695_1695_6_ACTG1-MITF_ACTG1_chr17_79478929_ENST00000575842_MITF_chr3_69986973_ENST00000394355_length(amino acids)=533AA_BP=130 MSPSFSGQVAMEEEIAALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWD DMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQVQTHLENPTKYHIQQAQRQQVKQYLSTTLANKHANQVLSLPCPNQPGDH VMPPVPGSSAPNSPMAMLTLNSNCEKEGFYKFEEQNRAESECPGMNTHSRASCMQMDDVIDDIISLESSYNEEILGLMDPALQMANTLPV SGNLIDLYGNQGLPPPGLTISNSCPANLPNIKRELTESEARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDMRWNKGTI LKASVDYIRKLQREQQRAKELENRQKKLEHANRHLLLRIQELEMQARAHGLSLIPSTGLCSPDLVNRIIKQEPVLENCSQDLLQHHADLT CTTTLDLTDGTITFNNNLGTGTEANQAYSVPTKMGSKLEDILMDDTLSPVGVTDPLLSSVSPGASKTSSRRSSMSMEETEHTC -------------------------------------------------------------- >1695_1695_7_ACTG1-MITF_ACTG1_chr17_79478929_ENST00000575842_MITF_chr3_69986973_ENST00000448226_length(transcript)=2798nt_BP=790nt CTCTCGCACTCTGTTCTTCCGCCGCTCCGCCGTCGCGTTTCTCTGCCGGTGAGCGCCCCGCCCCGGGGCCTGAGCTGGACGTCGCAGGCC TGCGCCCCCCGACCCCGGCTGGCCCCGCTTCCAGCTGCCGAGGCCTCGTCGCGCCTTCCCCGGGAACAAAAGGCGGGGTGGGCCGGGTCA GGCGGACGGGGCTGGGGGGGCGCCGGGGGTCCAGGGCGGGGCCCGGCCGCAGTGCAGACTTCCGAGCCGTGGACGTTACGTAAAAGGCCC GGCCTTCGGTTCCAGGCGGTTGCGATCTTGGAGGCCACGGCCGCTGGGGTTGGGGCAGGGCCGAGGCTTCCCCGCGGGAGGGCATTAGGT GGCTGTGGGGAGGGGACCGTGTTACAGACGCGCCCGCCTGAGTCCATCCTTTTCCGGGCAGGTCGCAATGGAAGAAGAGATCGCCGCGCT GGTCATTGACAATGGCTCCGGCATGTGCAAAGCTGGTTTTGCTGGGGACGACGCTCCCCGAGCCGTGTTTCCTTCCATCGTCGGGCGCCC CAGACACCAGGGCGTCATGGTGGGCATGGGCCAGAAGGACTCCTACGTGGGCGACGAGGCCCAGAGCAAGCGTGGCATCCTGACCCTGAA GTACCCCATTGAGCATGGCATCGTCACCAACTGGGACGACATGGAGAAGATCTGGCACCACACCTTCTACAACGAGCTGCGCGTGGCCCC GGAGGAGCACCCAGTGCTGCTGACCGAGGCCCCCCTGAACCCCAAGGCCAACAGAGAGAAGATGACTCAGGTGCAGACCCACCTCGAAAA CCCCACCAAGTACCACATACAGCAAGCCCAACGGCAGCAGGTAAAGCAGTACCTTTCTACCACTTTAGCAAATAAACATGCCAACCAAGT CCTGAGCTTGCCATGTCCAAACCAGCCTGGCGATCATGTCATGCCACCGGTGCCGGGGAGCAGCGCACCCAACAGCCCCATGGCTATGCT TACGCTTAACTCCAACTGTGAAAAAGAGGGATTTTATAAGTTTGAAGAGCAAAACAGGGCAGAGAGCGAGTGCCCAGGCATGAACACACA TTCACGAGCGTCCTGTATGCAGATGGATGATGTAATCGATGACATCATTAGCCTAGAATCAAGTTATAATGAGGAAATCTTGGGCTTGAT GGATCCTGCTTTGCAAATGGCAAATACGTTGCCTGTCTCGGGAAACTTGATTGATCTTTATGGAAACCAAGGTCTGCCCCCACCAGGCCT CACCATCAGCAACTCCTGTCCAGCCAACCTTCCCAACATAAAAAGGGAGCTCACAGCGTGTATTTTTCCCACAGAGTCTGAAGCAAGAGC ACTGGCCAAAGAGAGGCAGAAAAAGGACAATCACAACCTGATTGAACGAAGAAGAAGATTTAACATAAATGACCGCATTAAAGAACTAGG TACTTTGATTCCCAAGTCAAATGATCCAGACATGCGCTGGAACAAGGGAACCATCTTAAAAGCATCCGTGGACTATATCCGAAAGTTGCA ACGAGAACAGCAACGCGCAAAAGAACTTGAAAACCGACAGAAGAAACTGGAGCACGCCAACCGGCATTTGTTGCTCAGAATACAGGAACT TGAAATGCAGGCTCGAGCTCATGGACTTTCCCTTATTCCATCCACGGGTCTCTGCTCTCCAGATTTGGTGAATCGGATCATCAAGCAAGA ACCCGTTCTTGAGAACTGCAGCCAAGACCTCCTTCAGCATCATGCAGACCTAACCTGTACAACAACTCTCGATCTCACGGATGGCACCAT CACCTTCAACAACAACCTCGGAACTGGGACTGAGGCCAACCAAGCCTATAGTGTCCCCACAAAAATGGGATCCAAACTGGAAGACATCCT GATGGACGACACCCTTTCTCCCGTCGGTGTCACTGATCCACTCCTTTCCTCAGTGTCCCCCGGAGCTTCCAAAACAAGCAGCCGGAGGAG CAGTATGAGCATGGAAGAGACGGAGCACACTTGTTAGCGAATCCTCCCTGCACTGCATTCGCACAAACTGCTTCCTTTCTTGATTCGTAG ATTTAATAACTTACCTGAAGGGGTTTTCTTGATAATTTTCCTTTAATATGAAATTTTTTTTCATGCTTTATCAATAGCCCAGGATATATT TTATTTTTAGAATTTTGTGAAACAGACTTGTATATTCTATTTTACAACTACAAATGCCTCCAAAGTATTGTACAAATAAGTGTGCAGTAT CTGTGAACTGAATTCACCACAGACTTTAGCTTTCTGAGCAAGAGGATTTTGCGTCAGAGAAATGTCTGTCCATTTTTATTCAGGGGAAAC TTGATTTGAGATTTTTATGCCTGTGACTTCCTTGGAAATCAAATGTAAAGTTTAATTGAAAGAATGTAAAGCAACCAAAAAGAAAAAAAA AAAGAAAGAAAGAGGAAAAGAAATCCATACTAACCCTTTTCCATTTTATAAATGTATTGATTCATTGGTACTGCCTTAAAGATACAGTAC CCCTCTAGCTTTGTTTAGTCTTTATACTGCAAACTATTTAAAGAAATATGTATTCTGTAAAAGAAAAAAAAAATGCGGCCTTTTCATGAG GATCGTCTGGTTAGAAAACATAACTGATACCAACCGAAACTGAAGGGAGTTAGACCAAGGCTCTGAAATATAAAGTCTAATCTTGCTCTC TTTTATTCTGTGCTGTTACAGTTTTCTTCATCAATGAGTGTGATCCAGTTTTTCATAAGATATTTTATTTTGAAATGGAAATTAATGTCC TCTCAAAG >1695_1695_7_ACTG1-MITF_ACTG1_chr17_79478929_ENST00000575842_MITF_chr3_69986973_ENST00000448226_length(amino acids)=539AA_BP=130 MSPSFSGQVAMEEEIAALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWD DMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQVQTHLENPTKYHIQQAQRQQVKQYLSTTLANKHANQVLSLPCPNQPGDH VMPPVPGSSAPNSPMAMLTLNSNCEKEGFYKFEEQNRAESECPGMNTHSRASCMQMDDVIDDIISLESSYNEEILGLMDPALQMANTLPV SGNLIDLYGNQGLPPPGLTISNSCPANLPNIKRELTACIFPTESEARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDMR WNKGTILKASVDYIRKLQREQQRAKELENRQKKLEHANRHLLLRIQELEMQARAHGLSLIPSTGLCSPDLVNRIIKQEPVLENCSQDLLQ HHADLTCTTTLDLTDGTITFNNNLGTGTEANQAYSVPTKMGSKLEDILMDDTLSPVGVTDPLLSSVSPGASKTSSRRSSMSMEETEHTC -------------------------------------------------------------- >1695_1695_8_ACTG1-MITF_ACTG1_chr17_79478929_ENST00000575842_MITF_chr3_69986973_ENST00000472437_length(transcript)=2398nt_BP=790nt CTCTCGCACTCTGTTCTTCCGCCGCTCCGCCGTCGCGTTTCTCTGCCGGTGAGCGCCCCGCCCCGGGGCCTGAGCTGGACGTCGCAGGCC TGCGCCCCCCGACCCCGGCTGGCCCCGCTTCCAGCTGCCGAGGCCTCGTCGCGCCTTCCCCGGGAACAAAAGGCGGGGTGGGCCGGGTCA GGCGGACGGGGCTGGGGGGGCGCCGGGGGTCCAGGGCGGGGCCCGGCCGCAGTGCAGACTTCCGAGCCGTGGACGTTACGTAAAAGGCCC GGCCTTCGGTTCCAGGCGGTTGCGATCTTGGAGGCCACGGCCGCTGGGGTTGGGGCAGGGCCGAGGCTTCCCCGCGGGAGGGCATTAGGT GGCTGTGGGGAGGGGACCGTGTTACAGACGCGCCCGCCTGAGTCCATCCTTTTCCGGGCAGGTCGCAATGGAAGAAGAGATCGCCGCGCT GGTCATTGACAATGGCTCCGGCATGTGCAAAGCTGGTTTTGCTGGGGACGACGCTCCCCGAGCCGTGTTTCCTTCCATCGTCGGGCGCCC CAGACACCAGGGCGTCATGGTGGGCATGGGCCAGAAGGACTCCTACGTGGGCGACGAGGCCCAGAGCAAGCGTGGCATCCTGACCCTGAA GTACCCCATTGAGCATGGCATCGTCACCAACTGGGACGACATGGAGAAGATCTGGCACCACACCTTCTACAACGAGCTGCGCGTGGCCCC GGAGGAGCACCCAGTGCTGCTGACCGAGGCCCCCCTGAACCCCAAGGCCAACAGAGAGAAGATGACTCAGGTGCAGACCCACCTCGAAAA CCCCACCAAGTACCACATACAGCAAGCCCAACGGCAGCAGGTAAAGCAGTACCTTTCTACCACTTTAGCAAATAAACATGCCAACCAAGT CCTGAGCTTGCCATGTCCAAACCAGCCTGGCGATCATGTCATGCCACCGGTGCCGGGGAGCAGCGCACCCAACAGCCCCATGGCTATGCT TACGCTTAACTCCAACTGTGAAAAAGAGGGATTTTATAAGTTTGAAGAGCAAAACAGGGCAGAGAGCGAGTGCCCAGGCATGAACACACA TTCACGAGCGTCCTGTATGCAGATGGATGATGTAATCGATGACATCATTAGCCTAGAATCAAGTTATAATGAGGAAATCTTGGGCTTGAT GGATCCTGCTTTGCAAATGGCAAATACGTTGCCTGTCTCGGGAAACTTGATTGATCTTTATGGAAACCAAGGTCTGCCCCCACCAGGCCT CACCATCAGCAACTCCTGTCCAGCCAACCTTCCCAACATAAAAAGGGAGCTCACAGAGTCTGAAGCAAGAGCACTGGCCAAAGAGAGGCA GAAAAAGGACAATCACAACCTGATTGAACGAAGAAGAAGATTTAACATAAATGACCGCATTAAAGAACTAGGTACTTTGATTCCCAAGTC AAATGATCCAGACATGCGCTGGAACAAGGGAACCATCTTAAAAGCATCCGTGGACTATATCCGAAAGTTGCAACGAGAACAGCAACGCGC AAAAGAACTTGAAAACCGACAGAAGAAACTGGAGCACGCCAACCGGCATTTGTTGCTCAGAATACAGGAACTTGAAATGCAGGCTCGAGC TCATGGACTTTCCCTTATTCCATCCACGGGTCTCTGCTCTCCAGATTTGGTGAATCGGATCATCAAGCAAGAACCCGTTCTTGAGAACTG CAGCCAAGACCTCCTTCAGCATCATGCAGACCTAACCTGTACAACAACTCTCGATCTCACGGATGGCACCATCACCTTCAACAACAACCT CGGAACTGGGACTGAGGCCAACCAAGCCTATAGTGTCCCCACAAAAATGGGATCCAAACTGGAAGACATCCTGATGGACGACACCCTTTC TCCCGTCGGTGTCACTGATCCACTCCTTTCCTCAGTGTCCCCCGGAGCTTCCAAAACAAGCAGCCGGAGGAGCAGTATGAGCATGGAAGA GACGGAGCACACTTGTTAGCGAATCCTCCCTGCACTGCATTCGCACAAACTGCTTCCTTTCTTGATTCGTAGATTTAATAACTTACCTGA AGGGGTTTTCTTGATAATTTTCCTTTAATATGAAATTTTTTTTCATGCTTTATCAATAGCCCAGGATATATTTTATTTTTAGAATTTTGT GAAACAGACTTGTATATTCTATTTTACAACTACAAATGCCTCCAAAGTATTGTACAAATAAGTGTGCAGTATCTGTGAACTGAATTCACC ACAGACTTTAGCTTTCTGAGCAAGAGGATTTTGCGTCAGAGAAATGTCTGTCCATTTTTATTCAGGGGAAACTTGATTTGAGATTTTTAT GCCTGTGACTTCCTTGGAAATCAAATGTAAAGTTTAATTGAAAGAATGTAAAGCAACC >1695_1695_8_ACTG1-MITF_ACTG1_chr17_79478929_ENST00000575842_MITF_chr3_69986973_ENST00000472437_length(amino acids)=533AA_BP=130 MSPSFSGQVAMEEEIAALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWD DMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQVQTHLENPTKYHIQQAQRQQVKQYLSTTLANKHANQVLSLPCPNQPGDH VMPPVPGSSAPNSPMAMLTLNSNCEKEGFYKFEEQNRAESECPGMNTHSRASCMQMDDVIDDIISLESSYNEEILGLMDPALQMANTLPV SGNLIDLYGNQGLPPPGLTISNSCPANLPNIKRELTESEARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDMRWNKGTI LKASVDYIRKLQREQQRAKELENRQKKLEHANRHLLLRIQELEMQARAHGLSLIPSTGLCSPDLVNRIIKQEPVLENCSQDLLQHHADLT CTTTLDLTDGTITFNNNLGTGTEANQAYSVPTKMGSKLEDILMDDTLSPVGVTDPLLSSVSPGASKTSSRRSSMSMEETEHTC -------------------------------------------------------------- >1695_1695_9_ACTG1-MITF_ACTG1_chr17_79478929_ENST00000575842_MITF_chr3_69986973_ENST00000531774_length(transcript)=1831nt_BP=790nt CTCTCGCACTCTGTTCTTCCGCCGCTCCGCCGTCGCGTTTCTCTGCCGGTGAGCGCCCCGCCCCGGGGCCTGAGCTGGACGTCGCAGGCC TGCGCCCCCCGACCCCGGCTGGCCCCGCTTCCAGCTGCCGAGGCCTCGTCGCGCCTTCCCCGGGAACAAAAGGCGGGGTGGGCCGGGTCA GGCGGACGGGGCTGGGGGGGCGCCGGGGGTCCAGGGCGGGGCCCGGCCGCAGTGCAGACTTCCGAGCCGTGGACGTTACGTAAAAGGCCC GGCCTTCGGTTCCAGGCGGTTGCGATCTTGGAGGCCACGGCCGCTGGGGTTGGGGCAGGGCCGAGGCTTCCCCGCGGGAGGGCATTAGGT GGCTGTGGGGAGGGGACCGTGTTACAGACGCGCCCGCCTGAGTCCATCCTTTTCCGGGCAGGTCGCAATGGAAGAAGAGATCGCCGCGCT GGTCATTGACAATGGCTCCGGCATGTGCAAAGCTGGTTTTGCTGGGGACGACGCTCCCCGAGCCGTGTTTCCTTCCATCGTCGGGCGCCC CAGACACCAGGGCGTCATGGTGGGCATGGGCCAGAAGGACTCCTACGTGGGCGACGAGGCCCAGAGCAAGCGTGGCATCCTGACCCTGAA GTACCCCATTGAGCATGGCATCGTCACCAACTGGGACGACATGGAGAAGATCTGGCACCACACCTTCTACAACGAGCTGCGCGTGGCCCC GGAGGAGCACCCAGTGCTGCTGACCGAGGCCCCCCTGAACCCCAAGGCCAACAGAGAGAAGATGACTCAGGTGCAGACCCACCTCGAAAA CCCCACCAAGTACCACATACAGCAAGCCCAACGGCAGCAGGGATTTTATAAGTTTGAAGAGCAAAACAGGGCAGAGAGCGAGTGCCCAGG CATGAACACACATTCACGAGCGTCCTGTATGCAGATGGATGATGTAATCGATGACATCATTAGCCTAGAATCAAGTTATAATGAGGAAAT CTTGGGCTTGATGGATCCTGCTTTGCAAATGGCAAATACGTTGCCTGTCTCGGGAAACTTGATTGATCTTTATGGAAACCAAGGTCTGCC CCCACCAGGCCTCACCATCAGCAACTCCTGTCCAGCCAACCTTCCCAACATAAAAAGGGAGCTCACAGAGTCTGAAGCAAGAGCACTGGC CAAAGAGAGGCAGAAAAAGGACAATCACAACCTGATTGAACGAAGAAGAAGATTTAACATAAATGACCGCATTAAAGAACTAGGTACTTT GATTCCCAAGTCAAATGATCCAGACATGCGCTGGAACAAGGGAACCATCTTAAAAGCATCCGTGGACTATATCCGAAAGTTGCAACGAGA ACAGCAACGCGCAAAAGAACTTGAAAACCGACAGAAGAAACTGGAGCACGCCAACCGGCATTTGTTGCTCAGAATACAGGAACTTGAAAT GCAGGCTCGAGCTCATGGACTTTCCCTTATTCCATCCACGGGTCTCTGCTCTCCAGATTTGGTGAATCGGATCATCAAGCAAGAACCCGT TCTTGAGAACTGCAGCCAAGACCTCCTTCAGCATCATGCAGACCTAACCTGTACAACAACTCTCGATCTCACGGATGGCACCATCACCTT CAACAACAACCTCGGAACTGGGACTGAGGCCAACCAAGCCTATAGTGTCCCCACAAAAATGGGATCCAAACTGGAAGACATCCTGATGGA CGACACCCTTTCTCCCGTCGGTGTCACTGATCCACTCCTTTCCTCAGTGTCCCCCGGAGCTTCCAAAACAAGCAGCCGGAGGAGCAGTAT GAGCATGGAAGAGACGGAGCACACTTGTTAG >1695_1695_9_ACTG1-MITF_ACTG1_chr17_79478929_ENST00000575842_MITF_chr3_69986973_ENST00000531774_length(amino acids)=478AA_BP=130 MSPSFSGQVAMEEEIAALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWD DMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQVQTHLENPTKYHIQQAQRQQGFYKFEEQNRAESECPGMNTHSRASCMQM DDVIDDIISLESSYNEEILGLMDPALQMANTLPVSGNLIDLYGNQGLPPPGLTISNSCPANLPNIKRELTESEARALAKERQKKDNHNLI ERRRRFNINDRIKELGTLIPKSNDPDMRWNKGTILKASVDYIRKLQREQQRAKELENRQKKLEHANRHLLLRIQELEMQARAHGLSLIPS TGLCSPDLVNRIIKQEPVLENCSQDLLQHHADLTCTTTLDLTDGTITFNNNLGTGTEANQAYSVPTKMGSKLEDILMDDTLSPVGVTDPL LSSVSPGASKTSSRRSSMSMEETEHTCX -------------------------------------------------------------- |
Top |
Fusion Gene PPI Analysis for ACTG1-MITF |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for ACTG1-MITF |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
| Hgene | ACTG1 | P63261 | DB09130 | Copper | Small molecule | Approved|Investigational | |
| Hgene | ACTG1 | P63261 | DB09130 | Copper | Small molecule | Approved|Investigational |
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Related Diseases for ACTG1-MITF |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | ACTG1 | C3711374 | Nonsyndromic Deafness | 18 | CLINGEN |
| Hgene | ACTG1 | C1858172 | Deafness, Autosomal Dominant 20 | 8 | CTD_human;GENOMICS_ENGLAND;UNIPROT |
| Hgene | ACTG1 | C3281235 | BARAITSER-WINTER SYNDROME 2 | 4 | CLINGEN;CTD_human;GENOMICS_ENGLAND;UNIPROT |
| Hgene | ACTG1 | C0001787 | Osteoporosis, Age-Related | 1 | CTD_human |
| Hgene | ACTG1 | C0005745 | Blepharoptosis | 1 | GENOMICS_ENGLAND |
| Hgene | ACTG1 | C0007097 | Carcinoma | 1 | CTD_human |
| Hgene | ACTG1 | C0007621 | Neoplastic Cell Transformation | 1 | CTD_human |
| Hgene | ACTG1 | C0009363 | Congenital ocular coloboma (disorder) | 1 | CTD_human |
| Hgene | ACTG1 | C0014544 | Epilepsy | 1 | GENOMICS_ENGLAND |
| Hgene | ACTG1 | C0024433 | Macrostomia | 1 | GENOMICS_ENGLAND |
| Hgene | ACTG1 | C0024667 | Animal Mammary Neoplasms | 1 | CTD_human |
| Hgene | ACTG1 | C0024668 | Mammary Neoplasms, Experimental | 1 | CTD_human |
| Hgene | ACTG1 | C0029456 | Osteoporosis | 1 | CTD_human |
| Hgene | ACTG1 | C0029459 | Osteoporosis, Senile | 1 | CTD_human |
| Hgene | ACTG1 | C0033377 | Ptosis | 1 | GENOMICS_ENGLAND |
| Hgene | ACTG1 | C0205696 | Anaplastic carcinoma | 1 | CTD_human |
| Hgene | ACTG1 | C0205697 | Carcinoma, Spindle-Cell | 1 | CTD_human |
| Hgene | ACTG1 | C0205698 | Undifferentiated carcinoma | 1 | CTD_human |
| Hgene | ACTG1 | C0205699 | Carcinomatosis | 1 | CTD_human |
| Hgene | ACTG1 | C0240583 | Short upturned nose | 1 | GENOMICS_ENGLAND |
| Hgene | ACTG1 | C0265541 | Cranioschisis | 1 | CTD_human |
| Hgene | ACTG1 | C0266551 | Congenital coloboma of iris | 1 | ORPHANET |
| Hgene | ACTG1 | C0376634 | Craniofacial Abnormalities | 1 | CTD_human |
| Hgene | ACTG1 | C0497552 | Congenital neurologic anomalies | 1 | CTD_human |
| Hgene | ACTG1 | C0751406 | Post-Traumatic Osteoporosis | 1 | CTD_human |
| Hgene | ACTG1 | C0857379 | Abnormality of the pinna | 1 | GENOMICS_ENGLAND |
| Hgene | ACTG1 | C0948089 | Acute Coronary Syndrome | 1 | CTD_human |
| Hgene | ACTG1 | C1257925 | Mammary Carcinoma, Animal | 1 | CTD_human |
| Hgene | ACTG1 | C1384666 | hearing impairment | 1 | GENOMICS_ENGLAND |
| Hgene | ACTG1 | C1843156 | Progressive sensorineural hearing impairment | 1 | GENOMICS_ENGLAND |
| Hgene | ACTG1 | C1844505 | Pointed chin | 1 | GENOMICS_ENGLAND |
| Hgene | ACTG1 | C1849340 | Long palpebral fissure | 1 | GENOMICS_ENGLAND |
| Hgene | ACTG1 | C1855722 | Iris Coloboma with Ptosis, Hypertelorism, and Mental Retardation | 1 | ORPHANET |
| Hgene | ACTG1 | C1865014 | Long philtrum | 1 | GENOMICS_ENGLAND |
| Hgene | ACTG1 | C1865017 | Thin upper lip vermilion | 1 | GENOMICS_ENGLAND |
| Hgene | ACTG1 | C1868571 | Highly arched eyebrow | 1 | GENOMICS_ENGLAND |
| Hgene | ACTG1 | C1970280 | Hearing loss begins with loss of high frequencies | 1 | GENOMICS_ENGLAND |
| Hgene | ACTG1 | C1970281 | Audiogram shows sloping configuration | 1 | GENOMICS_ENGLAND |
| Hgene | ACTG1 | C1970282 | Deafness, profound, by 6th decade | 1 | GENOMICS_ENGLAND |
| Hgene | ACTG1 | C3279369 | Microphthalmia (in some patients) | 1 | GENOMICS_ENGLAND |
| Hgene | ACTG1 | C3549665 | Deafness (in some patients) | 1 | GENOMICS_ENGLAND |
| Hgene | ACTG1 | C3808883 | Short neck (in some patients) | 1 | GENOMICS_ENGLAND |
| Hgene | ACTG1 | C4012410 | Enlarged ventricles (in some patients) | 1 | GENOMICS_ENGLAND |
| Hgene | ACTG1 | C4229649 | Heart defect (in some patients) | 1 | GENOMICS_ENGLAND |
| Hgene | ACTG1 | C4229650 | Pterygium colli (in some patients) | 1 | GENOMICS_ENGLAND |
| Hgene | ACTG1 | C4229651 | Hypertelorism/telecanthus | 1 | GENOMICS_ENGLAND |
| Hgene | ACTG1 | C4229652 | Eye coloboma (in some patients) | 1 | GENOMICS_ENGLAND |
| Hgene | ACTG1 | C4229653 | Trigonocephaly/metopic ridge | 1 | GENOMICS_ENGLAND |
| Hgene | ACTG1 | C4231117 | Pectus (in some patients) | 1 | GENOMICS_ENGLAND |
| Hgene | ACTG1 | C4231118 | Kyphosis/scoliosis (in some patients) | 1 | GENOMICS_ENGLAND |
| Hgene | ACTG1 | C4231120 | Prominent nasal root on profile | 1 | GENOMICS_ENGLAND |
| Hgene | ACTG1 | C4231121 | Large, squared nose tip | 1 | GENOMICS_ENGLAND |
| Hgene | ACTG1 | C4231123 | Retrognathia (in some patients) | 1 | GENOMICS_ENGLAND |
| Hgene | ACTG1 | C4231124 | Prominent/full/wide cheeks | 1 | GENOMICS_ENGLAND |
| Hgene | ACTG1 | C4554007 | Uveoretinal Coloboma | 1 | CTD_human |
| Hgene | ACTG1 | C4708599 | Coloboma of choroid and retina | 1 | ORPHANET |
| Tgene | C2700265 | Waardenburg Syndrome Type 2 | 11 | CLINGEN;CTD_human;ORPHANET | |
| Tgene | C1860339 | WAARDENBURG SYNDROME, TYPE IIA | 5 | CTD_human;GENOMICS_ENGLAND;UNIPROT | |
| Tgene | C3152204 | MELANOMA, CUTANEOUS MALIGNANT, SUSCEPTIBILITY TO, 8 | 4 | CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT | |
| Tgene | C4310625 | COLOBOMA, OSTEOPETROSIS, MICROPHTHALMIA, MACROCEPHALY, ALBINISM, AND DEAFNESS | 3 | CTD_human;GENOMICS_ENGLAND;UNIPROT | |
| Tgene | C0391816 | Tietz syndrome | 2 | CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT | |
| Tgene | C1863198 | ALBINISM, OCULAR, WITH SENSORINEURAL DEAFNESS (disorder) | 2 | GENOMICS_ENGLAND;ORPHANET | |
| Tgene | C3266898 | Waardenburg Syndrome | 2 | GENOMICS_ENGLAND;ORPHANET | |
| Tgene | C0007134 | Renal Cell Carcinoma | 1 | CTD_human | |
| Tgene | C0007621 | Neoplastic Cell Transformation | 1 | CTD_human | |
| Tgene | C0011052 | Prelingual Deafness | 1 | CTD_human | |
| Tgene | C0011053 | Deafness | 1 | CTD_human | |
| Tgene | C0022283 | Incontinentia Pigmenti Achromians | 1 | CTD_human | |
| Tgene | C0025202 | melanoma | 1 | CGI;CTD_human | |
| Tgene | C0036305 | Schamberg Disease | 1 | CTD_human | |
| Tgene | C0078918 | Albinism, Oculocutaneous | 1 | CTD_human | |
| Tgene | C0078921 | Albinism, Tyrosinase-Negative | 1 | CTD_human | |
| Tgene | C0078922 | Albinism, Tyrosinase-Positive | 1 | CTD_human | |
| Tgene | C0078923 | Albinism, Yellow-Mutant | 1 | CTD_human | |
| Tgene | C0086395 | Hearing Loss, Extreme | 1 | CTD_human | |
| Tgene | C0151779 | Cutaneous Melanoma | 1 | CGI;CTD_human | |
| Tgene | C0279702 | Conventional (Clear Cell) Renal Cell Carcinoma | 1 | CTD_human | |
| Tgene | C0549567 | Pigmentation Disorders | 1 | CTD_human | |
| Tgene | C0581883 | Complete Hearing Loss | 1 | CTD_human | |
| Tgene | C0751068 | Deafness, Acquired | 1 | CTD_human | |
| Tgene | C1266042 | Chromophobe Renal Cell Carcinoma | 1 | CTD_human | |
| Tgene | C1266043 | Sarcomatoid Renal Cell Carcinoma | 1 | CTD_human | |
| Tgene | C1266044 | Collecting Duct Carcinoma of the Kidney | 1 | CTD_human | |
| Tgene | C1306837 | Papillary Renal Cell Carcinoma | 1 | CTD_human;ORPHANET | |
| Tgene | C1708353 | Hereditary Paraganglioma-Pheochromocytoma Syndrome | 1 | CLINGEN | |
| Tgene | C1848519 | WAARDENBURG SYNDROME, TYPE 4A | 1 | ORPHANET | |
| Tgene | C2314896 | Familial Atypical Mole Melanoma Syndrome | 1 | ORPHANET | |
| Tgene | C2700405 | WAARDENBURG SYNDROME, TYPE IIE | 1 | CTD_human | |
| Tgene | C3665473 | Bilateral Deafness | 1 | CTD_human | |
| Tgene | C4082305 | Deaf Mutism | 1 | CTD_human | |
| Tgene | C4518333 | Clear cell papillary renal cell carcinoma | 1 | ORPHANET | |
| Tgene | C4750999 | Ocular albinism with congenital sensorineural deafness | 1 | GENOMICS_ENGLAND |
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