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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:C4B-MSH5 (FusionGDB2 ID:HG721TG4439)

Fusion Gene Summary for C4B-MSH5

Fusion gene summary

Fusion gene information	Fusion gene name: C4B-MSH5
	Fusion gene ID: hg721tg4439
		Hgene	Tgene
	Gene symbol	C4B	MSH5
	Gene ID	721	4439
	Gene name	complement C4B (Chido blood group)	mutS homolog 5
	Synonyms	C4B1\|C4B12\|C4B2\|C4B3\|C4B5\|C4BD\|C4B_2\|C4F\|CH\|CO4\|CPAMD3	G7\|MUTSH5\|NG23\|POF13
	Cytomap	('C4B')('MSH5') 6p21.33	6p21.33
	Type of gene	protein-coding	protein-coding
	Description	complement C4-BC3 and PZP-like alpha-2-macroglobulin domain-containing protein 3Chido form of C4basic complement C4complement C4B1acomplement component 4B (Chido blood group)	mutS protein homolog 5
	Modification date	20200313	20200313
	UniProtAcc	.	O43196
	Ensembl transtripts involved in fusion gene	ENST00000425700, ENST00000435363, ENST00000375177, ENST00000411583, ENST00000445788, ENST00000449788, ENST00000485543, ENST00000487226, ENST00000488817, ENST00000494210, ENST00000546399, ENST00000548301, ENST00000548530, ENST00000550398,
Fusion gene scores	* DoF score	9 X 7 X 6=378	5 X 6 X 4=120
	# samples	8	5
	** MAII score	log2(8/378*10)=-2.24031432933371 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(5/120*10)=-1.26303440583379 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: C4B [Title/Abstract] AND MSH5 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	C4B(31984923)-MSH5(31732213), # samples:1
Anticipated loss of major functional domain due to fusion event.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	C4B	GO:0032490	detection of molecule of bacterial origin	22333221

Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	OV	TCGA-36-1581-01A	C4B	chr6	31984923	+	MSH5	chr6	31732213	+

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Fusion Gene ORF analysis for C4B-MSH5

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-3UTR	ENST00000425700	ENST00000534153	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-3UTR	ENST00000435363	ENST00000534153	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000425700	ENST00000375703	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000425700	ENST00000375740	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000425700	ENST00000375742	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000425700	ENST00000375750	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000425700	ENST00000375755	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000425700	ENST00000395853	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000425700	ENST00000414412	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000425700	ENST00000416549	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000425700	ENST00000419269	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000425700	ENST00000427735	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000425700	ENST00000430216	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000425700	ENST00000431848	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000425700	ENST00000435700	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000425700	ENST00000436004	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000425700	ENST00000436192	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000425700	ENST00000436559	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000425700	ENST00000439816	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000425700	ENST00000441395	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000425700	ENST00000441401	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000425700	ENST00000443040	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000425700	ENST00000448169	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000425700	ENST00000448617	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000425700	ENST00000456839	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000425700	ENST00000457742	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000425700	ENST00000457917	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000425700	ENST00000458144	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000425700	ENST00000460275	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000425700	ENST00000473342	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000425700	ENST00000478326	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000425700	ENST00000480915	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000425700	ENST00000482280	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000425700	ENST00000486924	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000425700	ENST00000490125	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000425700	ENST00000497157	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000425700	ENST00000549604	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000425700	ENST00000549746	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000425700	ENST00000578225	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000435363	ENST00000375703	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000435363	ENST00000375740	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000435363	ENST00000375742	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000435363	ENST00000375750	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000435363	ENST00000375755	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000435363	ENST00000395853	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000435363	ENST00000414412	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000435363	ENST00000416549	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000435363	ENST00000419269	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000435363	ENST00000427735	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000435363	ENST00000430216	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000435363	ENST00000431848	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000435363	ENST00000435700	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000435363	ENST00000436004	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000435363	ENST00000436192	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000435363	ENST00000436559	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000435363	ENST00000439816	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000435363	ENST00000441395	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000435363	ENST00000441401	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000435363	ENST00000443040	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000435363	ENST00000448169	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000435363	ENST00000448617	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000435363	ENST00000456839	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000435363	ENST00000457742	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000435363	ENST00000457917	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000435363	ENST00000458144	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000435363	ENST00000460275	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000435363	ENST00000473342	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000435363	ENST00000478326	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000435363	ENST00000480915	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000435363	ENST00000482280	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000435363	ENST00000486924	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000435363	ENST00000490125	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000435363	ENST00000497157	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000435363	ENST00000549604	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000435363	ENST00000549746	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
5CDS-intron	ENST00000435363	ENST00000578225	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-3UTR	ENST00000375177	ENST00000534153	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-3UTR	ENST00000411583	ENST00000534153	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-3UTR	ENST00000445788	ENST00000534153	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-3UTR	ENST00000449788	ENST00000534153	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-3UTR	ENST00000485543	ENST00000534153	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-3UTR	ENST00000487226	ENST00000534153	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-3UTR	ENST00000488817	ENST00000534153	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-3UTR	ENST00000494210	ENST00000534153	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-3UTR	ENST00000546399	ENST00000534153	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-3UTR	ENST00000548301	ENST00000534153	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-3UTR	ENST00000548530	ENST00000534153	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-3UTR	ENST00000550398	ENST00000534153	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000375177	ENST00000375703	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000375177	ENST00000375740	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000375177	ENST00000375742	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000375177	ENST00000375750	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000375177	ENST00000375755	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000375177	ENST00000395853	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000375177	ENST00000414412	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000375177	ENST00000416549	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000375177	ENST00000419269	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000375177	ENST00000427735	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000375177	ENST00000430216	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000375177	ENST00000431848	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000375177	ENST00000435700	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000375177	ENST00000436004	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000375177	ENST00000436192	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000375177	ENST00000436559	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000375177	ENST00000439816	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000375177	ENST00000441395	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000375177	ENST00000441401	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000375177	ENST00000443040	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000375177	ENST00000448169	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000375177	ENST00000448617	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000375177	ENST00000456839	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000375177	ENST00000457742	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000375177	ENST00000457917	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000375177	ENST00000458144	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000375177	ENST00000460275	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000375177	ENST00000473342	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000375177	ENST00000478326	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000375177	ENST00000480915	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000375177	ENST00000482280	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000375177	ENST00000486924	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000375177	ENST00000490125	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000375177	ENST00000497157	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000375177	ENST00000549604	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000375177	ENST00000549746	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000375177	ENST00000578225	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000411583	ENST00000375703	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000411583	ENST00000375740	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000411583	ENST00000375742	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000411583	ENST00000375750	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000411583	ENST00000375755	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000411583	ENST00000395853	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000411583	ENST00000414412	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000411583	ENST00000416549	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000411583	ENST00000419269	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000411583	ENST00000427735	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000411583	ENST00000430216	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000411583	ENST00000431848	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000411583	ENST00000435700	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000411583	ENST00000436004	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000411583	ENST00000436192	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000411583	ENST00000436559	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000411583	ENST00000439816	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000411583	ENST00000441395	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000411583	ENST00000441401	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000411583	ENST00000443040	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000411583	ENST00000448169	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000411583	ENST00000448617	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000411583	ENST00000456839	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000411583	ENST00000457742	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000411583	ENST00000457917	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000411583	ENST00000458144	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000411583	ENST00000460275	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000411583	ENST00000473342	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000411583	ENST00000478326	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000411583	ENST00000480915	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000411583	ENST00000482280	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000411583	ENST00000486924	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000411583	ENST00000490125	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000411583	ENST00000497157	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000411583	ENST00000549604	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000411583	ENST00000549746	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000411583	ENST00000578225	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000445788	ENST00000375703	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000445788	ENST00000375740	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000445788	ENST00000375742	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000445788	ENST00000375750	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000445788	ENST00000375755	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000445788	ENST00000395853	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000445788	ENST00000414412	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000445788	ENST00000416549	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000445788	ENST00000419269	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000445788	ENST00000427735	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000445788	ENST00000430216	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000445788	ENST00000431848	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000445788	ENST00000435700	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000445788	ENST00000436004	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000445788	ENST00000436192	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000445788	ENST00000436559	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000445788	ENST00000439816	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000445788	ENST00000441395	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000445788	ENST00000441401	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000445788	ENST00000443040	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000445788	ENST00000448169	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000445788	ENST00000448617	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000445788	ENST00000456839	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000445788	ENST00000457742	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000445788	ENST00000457917	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000445788	ENST00000458144	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000445788	ENST00000460275	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000445788	ENST00000473342	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000445788	ENST00000478326	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000445788	ENST00000480915	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000445788	ENST00000482280	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000445788	ENST00000486924	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000445788	ENST00000490125	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000445788	ENST00000497157	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000445788	ENST00000549604	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000445788	ENST00000549746	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000445788	ENST00000578225	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000449788	ENST00000375703	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000449788	ENST00000375740	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000449788	ENST00000375742	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000449788	ENST00000375750	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000449788	ENST00000375755	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000449788	ENST00000395853	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000449788	ENST00000414412	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000449788	ENST00000416549	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000449788	ENST00000419269	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000449788	ENST00000427735	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000449788	ENST00000430216	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000449788	ENST00000431848	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000449788	ENST00000435700	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000449788	ENST00000436004	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000449788	ENST00000436192	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000449788	ENST00000436559	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000449788	ENST00000439816	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000449788	ENST00000441395	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000449788	ENST00000441401	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000449788	ENST00000443040	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000449788	ENST00000448169	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000449788	ENST00000448617	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000449788	ENST00000456839	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000449788	ENST00000457742	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000449788	ENST00000457917	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000449788	ENST00000458144	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000449788	ENST00000460275	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000449788	ENST00000473342	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000449788	ENST00000478326	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000449788	ENST00000480915	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000449788	ENST00000482280	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000449788	ENST00000486924	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000449788	ENST00000490125	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000449788	ENST00000497157	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000449788	ENST00000549604	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000449788	ENST00000549746	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000449788	ENST00000578225	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000485543	ENST00000375703	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000485543	ENST00000375740	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000485543	ENST00000375742	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000485543	ENST00000375750	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000485543	ENST00000375755	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000485543	ENST00000395853	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000485543	ENST00000414412	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000485543	ENST00000416549	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000485543	ENST00000419269	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000485543	ENST00000427735	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000485543	ENST00000430216	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000485543	ENST00000431848	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000485543	ENST00000435700	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000485543	ENST00000436004	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000485543	ENST00000436192	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000485543	ENST00000436559	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000485543	ENST00000439816	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000485543	ENST00000441395	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000485543	ENST00000441401	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000485543	ENST00000443040	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000485543	ENST00000448169	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000485543	ENST00000448617	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000485543	ENST00000456839	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000485543	ENST00000457742	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000485543	ENST00000457917	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000485543	ENST00000458144	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000485543	ENST00000460275	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000485543	ENST00000473342	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000485543	ENST00000478326	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000485543	ENST00000480915	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000485543	ENST00000482280	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000485543	ENST00000486924	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000485543	ENST00000490125	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000485543	ENST00000497157	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000485543	ENST00000549604	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000485543	ENST00000549746	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000485543	ENST00000578225	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000487226	ENST00000375703	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000487226	ENST00000375740	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000487226	ENST00000375742	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000487226	ENST00000375750	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000487226	ENST00000375755	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000487226	ENST00000395853	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000487226	ENST00000414412	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000487226	ENST00000416549	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000487226	ENST00000419269	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000487226	ENST00000427735	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000487226	ENST00000430216	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000487226	ENST00000431848	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000487226	ENST00000435700	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000487226	ENST00000436004	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000487226	ENST00000436192	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000487226	ENST00000436559	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000487226	ENST00000439816	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000487226	ENST00000441395	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000487226	ENST00000441401	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000487226	ENST00000443040	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000487226	ENST00000448169	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000487226	ENST00000448617	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000487226	ENST00000456839	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000487226	ENST00000457742	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000487226	ENST00000457917	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000487226	ENST00000458144	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000487226	ENST00000460275	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000487226	ENST00000473342	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000487226	ENST00000478326	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000487226	ENST00000480915	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000487226	ENST00000482280	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000487226	ENST00000486924	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000487226	ENST00000490125	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000487226	ENST00000497157	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000487226	ENST00000549604	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000487226	ENST00000549746	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000487226	ENST00000578225	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000488817	ENST00000375703	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000488817	ENST00000375740	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000488817	ENST00000375742	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000488817	ENST00000375750	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000488817	ENST00000375755	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000488817	ENST00000395853	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000488817	ENST00000414412	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000488817	ENST00000416549	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000488817	ENST00000419269	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000488817	ENST00000427735	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000488817	ENST00000430216	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000488817	ENST00000431848	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000488817	ENST00000435700	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000488817	ENST00000436004	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000488817	ENST00000436192	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000488817	ENST00000436559	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000488817	ENST00000439816	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000488817	ENST00000441395	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000488817	ENST00000441401	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000488817	ENST00000443040	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000488817	ENST00000448169	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000488817	ENST00000448617	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000488817	ENST00000456839	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000488817	ENST00000457742	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000488817	ENST00000457917	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000488817	ENST00000458144	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000488817	ENST00000460275	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000488817	ENST00000473342	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000488817	ENST00000478326	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000488817	ENST00000480915	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000488817	ENST00000482280	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000488817	ENST00000486924	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000488817	ENST00000490125	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000488817	ENST00000497157	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000488817	ENST00000549604	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000488817	ENST00000549746	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000488817	ENST00000578225	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000494210	ENST00000375703	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000494210	ENST00000375740	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000494210	ENST00000375742	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000494210	ENST00000375750	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000494210	ENST00000375755	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000494210	ENST00000395853	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000494210	ENST00000414412	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000494210	ENST00000416549	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000494210	ENST00000419269	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000494210	ENST00000427735	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000494210	ENST00000430216	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000494210	ENST00000431848	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000494210	ENST00000435700	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000494210	ENST00000436004	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000494210	ENST00000436192	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000494210	ENST00000436559	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000494210	ENST00000439816	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000494210	ENST00000441395	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000494210	ENST00000441401	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000494210	ENST00000443040	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000494210	ENST00000448169	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000494210	ENST00000448617	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000494210	ENST00000456839	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000494210	ENST00000457742	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000494210	ENST00000457917	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000494210	ENST00000458144	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000494210	ENST00000460275	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000494210	ENST00000473342	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000494210	ENST00000478326	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000494210	ENST00000480915	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000494210	ENST00000482280	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000494210	ENST00000486924	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000494210	ENST00000490125	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000494210	ENST00000497157	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000494210	ENST00000549604	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000494210	ENST00000549746	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000494210	ENST00000578225	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000546399	ENST00000375703	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000546399	ENST00000375740	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000546399	ENST00000375742	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000546399	ENST00000375750	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000546399	ENST00000375755	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000546399	ENST00000395853	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000546399	ENST00000414412	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000546399	ENST00000416549	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000546399	ENST00000419269	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000546399	ENST00000427735	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000546399	ENST00000430216	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000546399	ENST00000431848	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000546399	ENST00000435700	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000546399	ENST00000436004	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000546399	ENST00000436192	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000546399	ENST00000436559	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000546399	ENST00000439816	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000546399	ENST00000441395	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000546399	ENST00000441401	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000546399	ENST00000443040	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000546399	ENST00000448169	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000546399	ENST00000448617	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000546399	ENST00000456839	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000546399	ENST00000457742	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000546399	ENST00000457917	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000546399	ENST00000458144	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000546399	ENST00000460275	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000546399	ENST00000473342	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000546399	ENST00000478326	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000546399	ENST00000480915	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000546399	ENST00000482280	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000546399	ENST00000486924	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000546399	ENST00000490125	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000546399	ENST00000497157	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000546399	ENST00000549604	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000546399	ENST00000549746	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000546399	ENST00000578225	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548301	ENST00000375703	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548301	ENST00000375740	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548301	ENST00000375742	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548301	ENST00000375750	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548301	ENST00000375755	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548301	ENST00000395853	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548301	ENST00000414412	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548301	ENST00000416549	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548301	ENST00000419269	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548301	ENST00000427735	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548301	ENST00000430216	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548301	ENST00000431848	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548301	ENST00000435700	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548301	ENST00000436004	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548301	ENST00000436192	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548301	ENST00000436559	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548301	ENST00000439816	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548301	ENST00000441395	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548301	ENST00000441401	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548301	ENST00000443040	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548301	ENST00000448169	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548301	ENST00000448617	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548301	ENST00000456839	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548301	ENST00000457742	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548301	ENST00000457917	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548301	ENST00000458144	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548301	ENST00000460275	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548301	ENST00000473342	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548301	ENST00000478326	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548301	ENST00000480915	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548301	ENST00000482280	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548301	ENST00000486924	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548301	ENST00000490125	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548301	ENST00000497157	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548301	ENST00000549604	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548301	ENST00000549746	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548301	ENST00000578225	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548530	ENST00000375703	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548530	ENST00000375740	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548530	ENST00000375742	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548530	ENST00000375750	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548530	ENST00000375755	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548530	ENST00000395853	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548530	ENST00000414412	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548530	ENST00000416549	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548530	ENST00000419269	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548530	ENST00000427735	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548530	ENST00000430216	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548530	ENST00000431848	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548530	ENST00000435700	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548530	ENST00000436004	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548530	ENST00000436192	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548530	ENST00000436559	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548530	ENST00000439816	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548530	ENST00000441395	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548530	ENST00000441401	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548530	ENST00000443040	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548530	ENST00000448169	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548530	ENST00000448617	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548530	ENST00000456839	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548530	ENST00000457742	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548530	ENST00000457917	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548530	ENST00000458144	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548530	ENST00000460275	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548530	ENST00000473342	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548530	ENST00000478326	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548530	ENST00000480915	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548530	ENST00000482280	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548530	ENST00000486924	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548530	ENST00000490125	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548530	ENST00000497157	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548530	ENST00000549604	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548530	ENST00000549746	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000548530	ENST00000578225	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000550398	ENST00000375703	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000550398	ENST00000375740	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000550398	ENST00000375742	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000550398	ENST00000375750	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000550398	ENST00000375755	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000550398	ENST00000395853	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000550398	ENST00000414412	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000550398	ENST00000416549	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000550398	ENST00000419269	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000550398	ENST00000427735	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000550398	ENST00000430216	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000550398	ENST00000431848	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000550398	ENST00000435700	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000550398	ENST00000436004	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000550398	ENST00000436192	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000550398	ENST00000436559	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000550398	ENST00000439816	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000550398	ENST00000441395	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000550398	ENST00000441401	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000550398	ENST00000443040	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000550398	ENST00000448169	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000550398	ENST00000448617	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000550398	ENST00000456839	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000550398	ENST00000457742	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000550398	ENST00000457917	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000550398	ENST00000458144	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000550398	ENST00000460275	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000550398	ENST00000473342	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000550398	ENST00000478326	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000550398	ENST00000480915	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000550398	ENST00000482280	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000550398	ENST00000486924	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000550398	ENST00000490125	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000550398	ENST00000497157	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000550398	ENST00000549604	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000550398	ENST00000549746	C4B	chr6	31984923	+	MSH5	chr6	31732213	+
intron-intron	ENST00000550398	ENST00000578225	C4B	chr6	31984923	+	MSH5	chr6	31732213	+

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst

Tenst

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

Seq length
(transcript)

BP loci
(transcript)

Predicted start
(transcript)

Predicted stop
(transcript)

Seq length
(amino acids)

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst

Tenst

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

No-coding score

Coding score

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Fusion Genomic Features for C4B-MSH5

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	1-p	p (fusion gene breakpoint)
C4B	chr6	31984923	+	MSH5	chr6	31732212	+	0.000212971	0.99978703
C4B	chr6	31984923	+	MSH5	chr6	31732212	+	0.000212971	0.99978703

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for C4B-MSH5

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/:31984923/:31732213)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	MSH5 O43196
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.	FUNCTION: Involved in DNA mismatch repair and meiotic recombination processes. Facilitates crossovers between homologs during meiosis (By similarity). {ECO:0000250}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

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Fusion Gene Sequence for C4B-MSH5

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

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Fusion Gene PPI Analysis for C4B-MSH5

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

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Related Drugs for C4B-MSH5

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for C4B-MSH5

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner	Gene	Disease ID	Disease name	# pubmeds	Source
Hgene	C4B	C0024141	Lupus Erythematosus, Systemic	7	ORPHANET
Hgene	C4B	C0004352	Autistic Disorder	2	CTD_human
Hgene	C4B	C0004364	Autoimmune Diseases	1	CTD_human
Hgene	C4B	C0011609	Drug Eruptions	1	CTD_human
Hgene	C4B	C0272242	Complement deficiency disease	1	GENOMICS_ENGLAND
Hgene	C4B	C0406537	Morbilliform Drug Reaction	1	CTD_human
Hgene	C4B	C3280641	Decreased serum complement C4b	1	CTD_human;GENOMICS_ENGLAND
Tgene		C2239176	Liver carcinoma	1	CTD_human
Tgene		C3469524	PROSTATE CANCER, SUSCEPTIBILITY TO	1	GENOMICS_ENGLAND
Tgene		C4479510	PREMATURE OVARIAN FAILURE 13	1	CTD_human;GENOMICS_ENGLAND;UNIPROT

Fusion Gene Studies in Kim Lab

Fusion gene:C4B-MSH5 (FusionGDB2 ID:HG721TG4439)

Fusion Gene Summary for C4B-MSH5

Fusion Gene ORF analysis for C4B-MSH5

Fusion Genomic Features for C4B-MSH5

Fusion Protein Features for C4B-MSH5

Fusion Gene Sequence for C4B-MSH5

Fusion Gene PPI Analysis for C4B-MSH5

Related Drugs for C4B-MSH5

Related Diseases for C4B-MSH5

Fusion Gene Studies
in Kim Lab