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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:DBNDD1-CRIP2 (FusionGDB2 ID:HG79007TG1397)

Fusion Gene Summary for DBNDD1-CRIP2

check button Fusion gene summary
Fusion gene informationFusion gene name: DBNDD1-CRIP2
Fusion gene ID: hg79007tg1397
HgeneTgene
Gene symbol

DBNDD1

CRIP2

Gene ID

79007

1397

Gene namedysbindin domain containing 1cysteine rich protein 2
Synonyms-CRIP|CRP2|ESP1
Cytomap('DBNDD1')('CRIP2')

16q24.3

14q32.33

Type of geneprotein-codingprotein-coding
Descriptiondysbindin domain-containing protein 1dysbindin (dystrobrevin binding protein 1) domain containing 1cysteine-rich protein 2Cysteine-rich intestinal proteinLIM domain protein ESP1/CRP2
Modification date2020031820200320
UniProtAcc

Q9H9R9

.
Ensembl transtripts involved in fusion geneENST00000002501, ENST00000304733, 
ENST00000392973, ENST00000568838, 
Fusion gene scores* DoF score3 X 2 X 2=125 X 4 X 2=40
# samples 34
** MAII scorelog2(3/12*10)=1.32192809488736
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(4/40*10)=0
Context

PubMed: DBNDD1 [Title/Abstract] AND CRIP2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointDBNDD1(90075192)-CRIP2(105944603), # samples:2
Anticipated loss of major functional domain due to fusion event.DBNDD1-CRIP2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
DBNDD1-CRIP2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
DBNDD1-CRIP2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
DBNDD1-CRIP2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across DBNDD1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across CRIP2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-EW-A6SA-01ADBNDD1chr16

90075192

-CRIP2chr14

105944603

+


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Fusion Gene ORF analysis for DBNDD1-CRIP2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000002501ENST00000548989DBNDD1chr16

90075192

-CRIP2chr14

105944603

+
5CDS-3UTRENST00000304733ENST00000548989DBNDD1chr16

90075192

-CRIP2chr14

105944603

+
5CDS-3UTRENST00000392973ENST00000548989DBNDD1chr16

90075192

-CRIP2chr14

105944603

+
5CDS-3UTRENST00000568838ENST00000548989DBNDD1chr16

90075192

-CRIP2chr14

105944603

+
In-frameENST00000002501ENST00000329146DBNDD1chr16

90075192

-CRIP2chr14

105944603

+
In-frameENST00000002501ENST00000483017DBNDD1chr16

90075192

-CRIP2chr14

105944603

+
In-frameENST00000304733ENST00000329146DBNDD1chr16

90075192

-CRIP2chr14

105944603

+
In-frameENST00000304733ENST00000483017DBNDD1chr16

90075192

-CRIP2chr14

105944603

+
In-frameENST00000392973ENST00000329146DBNDD1chr16

90075192

-CRIP2chr14

105944603

+
In-frameENST00000392973ENST00000483017DBNDD1chr16

90075192

-CRIP2chr14

105944603

+
In-frameENST00000568838ENST00000329146DBNDD1chr16

90075192

-CRIP2chr14

105944603

+
In-frameENST00000568838ENST00000483017DBNDD1chr16

90075192

-CRIP2chr14

105944603

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000304733DBNDD1chr1690075192-ENST00000483017CRIP2chr14105944603+1078453741036320
ENST00000304733DBNDD1chr1690075192-ENST00000329146CRIP2chr14105944603+1546453741036320
ENST00000002501DBNDD1chr1690075192-ENST00000483017CRIP2chr14105944603+1076451151034339
ENST00000002501DBNDD1chr1690075192-ENST00000329146CRIP2chr14105944603+1544451151034339
ENST00000392973DBNDD1chr1690075192-ENST00000483017CRIP2chr14105944603+169410695941652352
ENST00000392973DBNDD1chr1690075192-ENST00000329146CRIP2chr14105944603+216210691847705380
ENST00000568838DBNDD1chr1690075192-ENST00000483017CRIP2chr14105944603+1314689101272420
ENST00000568838DBNDD1chr1690075192-ENST00000329146CRIP2chr14105944603+1782689101272420

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000304733ENST00000483017DBNDD1chr1690075192-CRIP2chr14105944603+0.0383757460.96162426
ENST00000304733ENST00000329146DBNDD1chr1690075192-CRIP2chr14105944603+0.0249420850.97505784
ENST00000002501ENST00000483017DBNDD1chr1690075192-CRIP2chr14105944603+0.0291880440.9708119
ENST00000002501ENST00000329146DBNDD1chr1690075192-CRIP2chr14105944603+0.026678620.9733213
ENST00000392973ENST00000483017DBNDD1chr1690075192-CRIP2chr14105944603+0.0132983420.98670167
ENST00000392973ENST00000329146DBNDD1chr1690075192-CRIP2chr14105944603+0.0123000740.9877
ENST00000568838ENST00000483017DBNDD1chr1690075192-CRIP2chr14105944603+0.120533990.879466
ENST00000568838ENST00000329146DBNDD1chr1690075192-CRIP2chr14105944603+0.0889366340.9110634

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Fusion Genomic Features for DBNDD1-CRIP2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
DBNDD1chr1690075191-CRIP2chr14105944602+7.42E-101
DBNDD1chr1690075191-CRIP2chr14105944602+7.42E-101

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for DBNDD1-CRIP2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr16:90075192/chr14:105944603)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
DBNDD1

Q9H9R9

.
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneCRIP2chr16:90075192chr14:105944603ENST0000032914608180_19414209.0Compositional biasNote=Gly-rich
TgeneCRIP2chr16:90075192chr14:105944603ENST000003291460863_7314209.0Compositional biasNote=Gly-rich
TgeneCRIP2chr16:90075192chr14:105944603ENST0000048301708180_19488283.0Compositional biasNote=Gly-rich
TgeneCRIP2chr16:90075192chr14:105944603ENST0000032914608126_17814209.0DomainLIM zinc-binding 2
TgeneCRIP2chr16:90075192chr14:105944603ENST0000048301708126_17888283.0DomainLIM zinc-binding 2

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneCRIP2chr16:90075192chr14:105944603ENST000004830170863_7388283.0Compositional biasNote=Gly-rich
TgeneCRIP2chr16:90075192chr14:105944603ENST00000329146085_5714209.0DomainLIM zinc-binding 1
TgeneCRIP2chr16:90075192chr14:105944603ENST00000483017085_5788283.0DomainLIM zinc-binding 1


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Fusion Gene Sequence for DBNDD1-CRIP2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>21449_21449_1_DBNDD1-CRIP2_DBNDD1_chr16_90075192_ENST00000002501_CRIP2_chr14_105944603_ENST00000329146_length(transcript)=1544nt_BP=451nt
GCCGCGGCCCCCCGGTTGCTGCCCCGATGCGCTGCGCCCGGAGCCGGGGCCGAGTCGCTGCCGCAGCTGTTGGGGCGCCCGGGCCAGGCG
ACGCCGCCGTCGCCCGTGCCCCTCCCAGACCGCACCGGCCGCATGGAGCCCCCGGAGGGCGCCGGCACCGGAGAGATCGTTAAGGAGGCT
GAGGTGCCGCAGGCTGCGCTGGGCGTCCCAGCCCAGGGGACAGGGGACAATGGCCACACGCCTGTGGAGGAGGAGGTCGGGGGCATCCCA
GTACCAGCACCGGGGCTCCTGCAGGTCACGGAGAGGAGGCAGCCTCTGAGCAGCGTCTCCTCTCTGGAGGTCCACTTCGACCTCCTGGAC
CTCACTGAGCTCACCGACATGTCGGACCAGGAGCTGGCCGAGGTCTTTGCTGACTCGGACGACGAGAACCTCAACACCGAGTCCCCAGCA
GCCGAGAAGGTGAGCTCCCTGGGGAAGGACTGGCACAAGTTCTGCCTCAAGTGCGAGCGCTGCAGCAAGACGCTGACGCCCGGGGGCCAC
GCCGAGCATGACGGGAAGCCGTTCTGCCACAAGCCGTGCTACGCCACCCTGTTCGGACCCAAAGGCGTGAACATCGGGGGCGCGGGCTCC
TACATCTACGAGAAGCCCCTGGCGGAGGGGCCGCAGGTCACCGGCCCCATCGAGGTCCCCGCGGCCCGAGCAGAGGAGCGGAAGGCGAGC
GGCCCCCCGAAGGGGCCCAGCAGAGCCTCCAGTGTCACCACTTTCACCGGGGAGCCCAACACGTGCCCGCGCTGCAGCAAGAAGGTGTAC
TTCGCTGAGAAGGTGACGTCTCTGGGCAAGGATTGGCACCGGCCCTGCCTGCGCTGCGAGCGCTGCGGGAAGACACTGACCCCCGGCGGG
CACGCGGAGCACGACGGCCAGCCCTACTGCCACAAGCCCTGCTATGGAATCCTCTTCGGACCCAAGGGAGTGAACACCGGTGCGGTGGGC
AGCTACATCTATGACCGGGACCCCGAAGGCAAGGTCCAGCCCTAGGCTACAGCGGCTCTCATGATGTGGGCTCACCTGCGCCCCAGACCC
TGCAGGGGCCCCCCTGCTTGGCTCTGCTGGGAGAGTGCTCAGCCGCCCAGTCCTGCCTGCAAGCCCAGGGCGAGTATTGGAGGAGGGGCA
GCCACGGGCAGAGCACCATGCCCATCCCCGAGTCTCTGGTGTGTCTGCCCCCTCTGGCATCCTCTGGGCGTCCCATGATCCCTTCTGTGT
CTGCGTGTCCGAATCCCCGTGTGACCCTGTCCCAGCATTTTCCCGCCGACCCTGCGTGTCCCCGTGGCGCTGTCCGCTCTCCCTCTCCTG
CTGCCCACCCACCTGCCAGTGTTATTTATGCTCCCTTCGTGGGTGATGGCCACGCCCTCACCATGTCCCTGGCAGAGGGCTTCCCTCCGG
GATCCCCTGCCTGGTGCCCACACTGCCTCGCAAGCGCTCGCCACCCTCACGTGGCTCACCTGCTGTTGAGCCTTGTGCTGTCAATAAACG
GTTTGAGGATTGCA

>21449_21449_1_DBNDD1-CRIP2_DBNDD1_chr16_90075192_ENST00000002501_CRIP2_chr14_105944603_ENST00000329146_length(amino acids)=339AA_BP=266
MLPRCAAPGAGAESLPQLLGRPGQATPPSPVPLPDRTGRMEPPEGAGTGEIVKEAEVPQAALGVPAQGTGDNGHTPVEEEVGGIPVPAPG
LLQVTERRQPLSSVSSLEVHFDLLDLTELTDMSDQELAEVFADSDDENLNTESPAAEKVSSLGKDWHKFCLKCERCSKTLTPGGHAEHDG
KPFCHKPCYATLFGPKGVNIGGAGSYIYEKPLAEGPQVTGPIEVPAARAEERKASGPPKGPSRASSVTTFTGEPNTCPRCSKKVYFAEKV
TSLGKDWHRPCLRCERCGKTLTPGGHAEHDGQPYCHKPCYGILFGPKGVNTGAVGSYIYDRDPEGKVQP

--------------------------------------------------------------
>21449_21449_2_DBNDD1-CRIP2_DBNDD1_chr16_90075192_ENST00000002501_CRIP2_chr14_105944603_ENST00000483017_length(transcript)=1076nt_BP=451nt
GCCGCGGCCCCCCGGTTGCTGCCCCGATGCGCTGCGCCCGGAGCCGGGGCCGAGTCGCTGCCGCAGCTGTTGGGGCGCCCGGGCCAGGCG
ACGCCGCCGTCGCCCGTGCCCCTCCCAGACCGCACCGGCCGCATGGAGCCCCCGGAGGGCGCCGGCACCGGAGAGATCGTTAAGGAGGCT
GAGGTGCCGCAGGCTGCGCTGGGCGTCCCAGCCCAGGGGACAGGGGACAATGGCCACACGCCTGTGGAGGAGGAGGTCGGGGGCATCCCA
GTACCAGCACCGGGGCTCCTGCAGGTCACGGAGAGGAGGCAGCCTCTGAGCAGCGTCTCCTCTCTGGAGGTCCACTTCGACCTCCTGGAC
CTCACTGAGCTCACCGACATGTCGGACCAGGAGCTGGCCGAGGTCTTTGCTGACTCGGACGACGAGAACCTCAACACCGAGTCCCCAGCA
GCCGAGAAGGTGAGCTCCCTGGGGAAGGACTGGCACAAGTTCTGCCTCAAGTGCGAGCGCTGCAGCAAGACGCTGACGCCCGGGGGCCAC
GCCGAGCATGACGGGAAGCCGTTCTGCCACAAGCCGTGCTACGCCACCCTGTTCGGACCCAAAGGCGTGAACATCGGGGGCGCGGGCTCC
TACATCTACGAGAAGCCCCTGGCGGAGGGGCCGCAGGTCACCGGCCCCATCGAGGTCCCCGCGGCCCGAGCAGAGGAGCGGAAGGCGAGC
GGCCCCCCGAAGGGGCCCAGCAGAGCCTCCAGTGTCACCACTTTCACCGGGGAGCCCAACACGTGCCCGCGCTGCAGCAAGAAGGTGTAC
TTCGCTGAGAAGGTGACGTCTCTGGGCAAGGATTGGCACCGGCCCTGCCTGCGCTGCGAGCGCTGCGGGAAGACACTGACCCCCGGCGGG
CACGCGGAGCACGACGGCCAGCCCTACTGCCACAAGCCCTGCTATGGAATCCTCTTCGGACCCAAGGGAGTGAACACCGGTGCGGTGGGC
AGCTACATCTATGACCGGGACCCCGAAGGCAAGGTCCAGCCCTAGGCTACAGCGGCTCTCATGATGTGGGCTCACCTGCGCCCCAG

>21449_21449_2_DBNDD1-CRIP2_DBNDD1_chr16_90075192_ENST00000002501_CRIP2_chr14_105944603_ENST00000483017_length(amino acids)=339AA_BP=266
MLPRCAAPGAGAESLPQLLGRPGQATPPSPVPLPDRTGRMEPPEGAGTGEIVKEAEVPQAALGVPAQGTGDNGHTPVEEEVGGIPVPAPG
LLQVTERRQPLSSVSSLEVHFDLLDLTELTDMSDQELAEVFADSDDENLNTESPAAEKVSSLGKDWHKFCLKCERCSKTLTPGGHAEHDG
KPFCHKPCYATLFGPKGVNIGGAGSYIYEKPLAEGPQVTGPIEVPAARAEERKASGPPKGPSRASSVTTFTGEPNTCPRCSKKVYFAEKV
TSLGKDWHRPCLRCERCGKTLTPGGHAEHDGQPYCHKPCYGILFGPKGVNTGAVGSYIYDRDPEGKVQP

--------------------------------------------------------------
>21449_21449_3_DBNDD1-CRIP2_DBNDD1_chr16_90075192_ENST00000304733_CRIP2_chr14_105944603_ENST00000329146_length(transcript)=1546nt_BP=453nt
GTGAGCCGAGATTGCACCACTGCACTCCAGCCTGGGTGACAGAGCGAGACTCCATCTAAAAAAAATAAATAAACATGGGAGAAACCTGGA
AGAATATTTGCTCAACTGTGAGGCATGGTTGGTGGCTAAGGGATCACAGAATGGCAGGCCTGCCTATTCCTCCTGAGATCGTTAAGGAGG
CTGAGGTGCCGCAGGCTGCGCTGGGCGTCCCAGCCCAGGGGACAGGGGACAATGGCCACACGCCTGTGGAGGAGGAGGTCGGGGGCATCC
CAGTACCAGCACCGGGGCTCCTGCAGGTCACGGAGAGGAGGCAGCCTCTGAGCAGCGTCTCCTCTCTGGAGGTCCACTTCGACCTCCTGG
ACCTCACTGAGCTCACCGACATGTCGGACCAGGAGCTGGCCGAGGTCTTTGCTGACTCGGACGACGAGAACCTCAACACCGAGTCCCCAG
CAGCCGAGAAGGTGAGCTCCCTGGGGAAGGACTGGCACAAGTTCTGCCTCAAGTGCGAGCGCTGCAGCAAGACGCTGACGCCCGGGGGCC
ACGCCGAGCATGACGGGAAGCCGTTCTGCCACAAGCCGTGCTACGCCACCCTGTTCGGACCCAAAGGCGTGAACATCGGGGGCGCGGGCT
CCTACATCTACGAGAAGCCCCTGGCGGAGGGGCCGCAGGTCACCGGCCCCATCGAGGTCCCCGCGGCCCGAGCAGAGGAGCGGAAGGCGA
GCGGCCCCCCGAAGGGGCCCAGCAGAGCCTCCAGTGTCACCACTTTCACCGGGGAGCCCAACACGTGCCCGCGCTGCAGCAAGAAGGTGT
ACTTCGCTGAGAAGGTGACGTCTCTGGGCAAGGATTGGCACCGGCCCTGCCTGCGCTGCGAGCGCTGCGGGAAGACACTGACCCCCGGCG
GGCACGCGGAGCACGACGGCCAGCCCTACTGCCACAAGCCCTGCTATGGAATCCTCTTCGGACCCAAGGGAGTGAACACCGGTGCGGTGG
GCAGCTACATCTATGACCGGGACCCCGAAGGCAAGGTCCAGCCCTAGGCTACAGCGGCTCTCATGATGTGGGCTCACCTGCGCCCCAGAC
CCTGCAGGGGCCCCCCTGCTTGGCTCTGCTGGGAGAGTGCTCAGCCGCCCAGTCCTGCCTGCAAGCCCAGGGCGAGTATTGGAGGAGGGG
CAGCCACGGGCAGAGCACCATGCCCATCCCCGAGTCTCTGGTGTGTCTGCCCCCTCTGGCATCCTCTGGGCGTCCCATGATCCCTTCTGT
GTCTGCGTGTCCGAATCCCCGTGTGACCCTGTCCCAGCATTTTCCCGCCGACCCTGCGTGTCCCCGTGGCGCTGTCCGCTCTCCCTCTCC
TGCTGCCCACCCACCTGCCAGTGTTATTTATGCTCCCTTCGTGGGTGATGGCCACGCCCTCACCATGTCCCTGGCAGAGGGCTTCCCTCC
GGGATCCCCTGCCTGGTGCCCACACTGCCTCGCAAGCGCTCGCCACCCTCACGTGGCTCACCTGCTGTTGAGCCTTGTGCTGTCAATAAA
CGGTTTGAGGATTGCA

>21449_21449_3_DBNDD1-CRIP2_DBNDD1_chr16_90075192_ENST00000304733_CRIP2_chr14_105944603_ENST00000329146_length(amino acids)=320AA_BP=247
MGETWKNICSTVRHGWWLRDHRMAGLPIPPEIVKEAEVPQAALGVPAQGTGDNGHTPVEEEVGGIPVPAPGLLQVTERRQPLSSVSSLEV
HFDLLDLTELTDMSDQELAEVFADSDDENLNTESPAAEKVSSLGKDWHKFCLKCERCSKTLTPGGHAEHDGKPFCHKPCYATLFGPKGVN
IGGAGSYIYEKPLAEGPQVTGPIEVPAARAEERKASGPPKGPSRASSVTTFTGEPNTCPRCSKKVYFAEKVTSLGKDWHRPCLRCERCGK
TLTPGGHAEHDGQPYCHKPCYGILFGPKGVNTGAVGSYIYDRDPEGKVQP

--------------------------------------------------------------
>21449_21449_4_DBNDD1-CRIP2_DBNDD1_chr16_90075192_ENST00000304733_CRIP2_chr14_105944603_ENST00000483017_length(transcript)=1078nt_BP=453nt
GTGAGCCGAGATTGCACCACTGCACTCCAGCCTGGGTGACAGAGCGAGACTCCATCTAAAAAAAATAAATAAACATGGGAGAAACCTGGA
AGAATATTTGCTCAACTGTGAGGCATGGTTGGTGGCTAAGGGATCACAGAATGGCAGGCCTGCCTATTCCTCCTGAGATCGTTAAGGAGG
CTGAGGTGCCGCAGGCTGCGCTGGGCGTCCCAGCCCAGGGGACAGGGGACAATGGCCACACGCCTGTGGAGGAGGAGGTCGGGGGCATCC
CAGTACCAGCACCGGGGCTCCTGCAGGTCACGGAGAGGAGGCAGCCTCTGAGCAGCGTCTCCTCTCTGGAGGTCCACTTCGACCTCCTGG
ACCTCACTGAGCTCACCGACATGTCGGACCAGGAGCTGGCCGAGGTCTTTGCTGACTCGGACGACGAGAACCTCAACACCGAGTCCCCAG
CAGCCGAGAAGGTGAGCTCCCTGGGGAAGGACTGGCACAAGTTCTGCCTCAAGTGCGAGCGCTGCAGCAAGACGCTGACGCCCGGGGGCC
ACGCCGAGCATGACGGGAAGCCGTTCTGCCACAAGCCGTGCTACGCCACCCTGTTCGGACCCAAAGGCGTGAACATCGGGGGCGCGGGCT
CCTACATCTACGAGAAGCCCCTGGCGGAGGGGCCGCAGGTCACCGGCCCCATCGAGGTCCCCGCGGCCCGAGCAGAGGAGCGGAAGGCGA
GCGGCCCCCCGAAGGGGCCCAGCAGAGCCTCCAGTGTCACCACTTTCACCGGGGAGCCCAACACGTGCCCGCGCTGCAGCAAGAAGGTGT
ACTTCGCTGAGAAGGTGACGTCTCTGGGCAAGGATTGGCACCGGCCCTGCCTGCGCTGCGAGCGCTGCGGGAAGACACTGACCCCCGGCG
GGCACGCGGAGCACGACGGCCAGCCCTACTGCCACAAGCCCTGCTATGGAATCCTCTTCGGACCCAAGGGAGTGAACACCGGTGCGGTGG
GCAGCTACATCTATGACCGGGACCCCGAAGGCAAGGTCCAGCCCTAGGCTACAGCGGCTCTCATGATGTGGGCTCACCTGCGCCCCAG

>21449_21449_4_DBNDD1-CRIP2_DBNDD1_chr16_90075192_ENST00000304733_CRIP2_chr14_105944603_ENST00000483017_length(amino acids)=320AA_BP=247
MGETWKNICSTVRHGWWLRDHRMAGLPIPPEIVKEAEVPQAALGVPAQGTGDNGHTPVEEEVGGIPVPAPGLLQVTERRQPLSSVSSLEV
HFDLLDLTELTDMSDQELAEVFADSDDENLNTESPAAEKVSSLGKDWHKFCLKCERCSKTLTPGGHAEHDGKPFCHKPCYATLFGPKGVN
IGGAGSYIYEKPLAEGPQVTGPIEVPAARAEERKASGPPKGPSRASSVTTFTGEPNTCPRCSKKVYFAEKVTSLGKDWHRPCLRCERCGK
TLTPGGHAEHDGQPYCHKPCYGILFGPKGVNTGAVGSYIYDRDPEGKVQP

--------------------------------------------------------------
>21449_21449_5_DBNDD1-CRIP2_DBNDD1_chr16_90075192_ENST00000392973_CRIP2_chr14_105944603_ENST00000329146_length(transcript)=2162nt_BP=1069nt
TAGCCGGGCGTGCTGGTGCATGCCTGTAATCCCATCTACTCAGGGGGATGAGGCAGGAGAATCGCTCAAACCCAAGGGGCAGAGGTTGCA
GTGAGCCGAGATTGCACCACTGCACTCCAGCCTGGGTGACAGAGCGAGACTCCATCTAAAAAAAATAAATAAACATGGGAGAAACCTGGA
AGAATATTTGCTCAACTGTGAGGCATGGTTGGTGGCTAAGGGATCACAGAATGGCAGGCCTGCCTATTCCTCCTGGTTTGTAACTTTCAT
TTAATGAGAATGTATTATTCTGAACTCAAATACGACATCAGTTTTTAAAAGGAAAAGTCAGTCCACAGTGGAGAGGGGCTGTTCTGGTTT
GAAGGGGACCAAGAGGCTGGACATGGAAATCCATGGGCGATCCTTCAGGGGACCCTGGGCCGAGCTAGAAATCAGAGGCCAGGACGGCAC
TGGAATGCAGCCACGCGGGCCCTGGTGGGACTTCCACGCCTGCATGGTCGGCTTTCATGGGTGCTTGCGTACCAAAGGTGATCTGGATCT
CAGATTCCTTGTTCACTAGGGGAGGCCAGGGCCCAAGGGGAAGGAGCAGCCTCCTTGAAGCCCCTCAACCCCTTGTCTGGGTCCAGGCAT
GAGGCCACAAGCCCAGCCATCCCATCACCTGCTGGTCACTGCCCAGAGTTTCAAAGGACTGGATGTGCCAAGTCCTCACACCCAGCCCCG
CGTCCTGGGGGGATGTGGGAGCCCTGTGGATCTCAAGGTGACACTGTGTCTTTGGATGCAGAGATCGTTAAGGAGGCTGAGGTGCCGCAG
GCTGCGCTGGGCGTCCCAGCCCAGGGGACAGGGGACAATGGCCACACGCCTGTGGAGGAGGAGGTCGGGGGCATCCCAGTACCAGCACCG
GGGCTCCTGCAGGTCACGGAGAGGAGGCAGCCTCTGAGCAGCGTCTCCTCTCTGGAGGTCCACTTCGACCTCCTGGACCTCACTGAGCTC
ACCGACATGTCGGACCAGGAGCTGGCCGAGGTCTTTGCTGACTCGGACGACGAGAACCTCAACACCGAGTCCCCAGCAGCCGAGAAGGTG
AGCTCCCTGGGGAAGGACTGGCACAAGTTCTGCCTCAAGTGCGAGCGCTGCAGCAAGACGCTGACGCCCGGGGGCCACGCCGAGCATGAC
GGGAAGCCGTTCTGCCACAAGCCGTGCTACGCCACCCTGTTCGGACCCAAAGGCGTGAACATCGGGGGCGCGGGCTCCTACATCTACGAG
AAGCCCCTGGCGGAGGGGCCGCAGGTCACCGGCCCCATCGAGGTCCCCGCGGCCCGAGCAGAGGAGCGGAAGGCGAGCGGCCCCCCGAAG
GGGCCCAGCAGAGCCTCCAGTGTCACCACTTTCACCGGGGAGCCCAACACGTGCCCGCGCTGCAGCAAGAAGGTGTACTTCGCTGAGAAG
GTGACGTCTCTGGGCAAGGATTGGCACCGGCCCTGCCTGCGCTGCGAGCGCTGCGGGAAGACACTGACCCCCGGCGGGCACGCGGAGCAC
GACGGCCAGCCCTACTGCCACAAGCCCTGCTATGGAATCCTCTTCGGACCCAAGGGAGTGAACACCGGTGCGGTGGGCAGCTACATCTAT
GACCGGGACCCCGAAGGCAAGGTCCAGCCCTAGGCTACAGCGGCTCTCATGATGTGGGCTCACCTGCGCCCCAGACCCTGCAGGGGCCCC
CCTGCTTGGCTCTGCTGGGAGAGTGCTCAGCCGCCCAGTCCTGCCTGCAAGCCCAGGGCGAGTATTGGAGGAGGGGCAGCCACGGGCAGA
GCACCATGCCCATCCCCGAGTCTCTGGTGTGTCTGCCCCCTCTGGCATCCTCTGGGCGTCCCATGATCCCTTCTGTGTCTGCGTGTCCGA
ATCCCCGTGTGACCCTGTCCCAGCATTTTCCCGCCGACCCTGCGTGTCCCCGTGGCGCTGTCCGCTCTCCCTCTCCTGCTGCCCACCCAC
CTGCCAGTGTTATTTATGCTCCCTTCGTGGGTGATGGCCACGCCCTCACCATGTCCCTGGCAGAGGGCTTCCCTCCGGGATCCCCTGCCT
GGTGCCCACACTGCCTCGCAAGCGCTCGCCACCCTCACGTGGCTCACCTGCTGTTGAGCCTTGTGCTGTCAATAAACGGTTTGAGGATTG
CA

>21449_21449_5_DBNDD1-CRIP2_DBNDD1_chr16_90075192_ENST00000392973_CRIP2_chr14_105944603_ENST00000329146_length(amino acids)=380AA_BP=0
MPEGADTPETRGWAWCSARGCPSSNTRPGLAGRTGRLSTLPAEPSRGAPAGSGAQVSPHHESRCSLGLDLAFGVPVIDVAAHRTGVHSLG
SEEDSIAGLVAVGLAVVLRVPAGGQCLPAALAAQAGPVPILAQRRHLLSEVHLLAAARARVGLPGESGDTGGSAGPLRGAARLPLLCSGR
GDLDGAGDLRPLRQGLLVDVGARAPDVHAFGSEQGGVARLVAERLPVMLGVAPGRQRLAAALALEAELVPVLPQGAHLLGCWGLGVEVLV
VRVSKDLGQLLVRHVGELSEVQEVEVDLQRGDAAQRLPPLRDLQEPRCWYWDAPDLLLHRRVAIVPCPLGWDAQRSLRHLSLLNDLCIQR
HSVTLRSTGLPHPPRTRGWV

--------------------------------------------------------------
>21449_21449_6_DBNDD1-CRIP2_DBNDD1_chr16_90075192_ENST00000392973_CRIP2_chr14_105944603_ENST00000483017_length(transcript)=1694nt_BP=1069nt
TAGCCGGGCGTGCTGGTGCATGCCTGTAATCCCATCTACTCAGGGGGATGAGGCAGGAGAATCGCTCAAACCCAAGGGGCAGAGGTTGCA
GTGAGCCGAGATTGCACCACTGCACTCCAGCCTGGGTGACAGAGCGAGACTCCATCTAAAAAAAATAAATAAACATGGGAGAAACCTGGA
AGAATATTTGCTCAACTGTGAGGCATGGTTGGTGGCTAAGGGATCACAGAATGGCAGGCCTGCCTATTCCTCCTGGTTTGTAACTTTCAT
TTAATGAGAATGTATTATTCTGAACTCAAATACGACATCAGTTTTTAAAAGGAAAAGTCAGTCCACAGTGGAGAGGGGCTGTTCTGGTTT
GAAGGGGACCAAGAGGCTGGACATGGAAATCCATGGGCGATCCTTCAGGGGACCCTGGGCCGAGCTAGAAATCAGAGGCCAGGACGGCAC
TGGAATGCAGCCACGCGGGCCCTGGTGGGACTTCCACGCCTGCATGGTCGGCTTTCATGGGTGCTTGCGTACCAAAGGTGATCTGGATCT
CAGATTCCTTGTTCACTAGGGGAGGCCAGGGCCCAAGGGGAAGGAGCAGCCTCCTTGAAGCCCCTCAACCCCTTGTCTGGGTCCAGGCAT
GAGGCCACAAGCCCAGCCATCCCATCACCTGCTGGTCACTGCCCAGAGTTTCAAAGGACTGGATGTGCCAAGTCCTCACACCCAGCCCCG
CGTCCTGGGGGGATGTGGGAGCCCTGTGGATCTCAAGGTGACACTGTGTCTTTGGATGCAGAGATCGTTAAGGAGGCTGAGGTGCCGCAG
GCTGCGCTGGGCGTCCCAGCCCAGGGGACAGGGGACAATGGCCACACGCCTGTGGAGGAGGAGGTCGGGGGCATCCCAGTACCAGCACCG
GGGCTCCTGCAGGTCACGGAGAGGAGGCAGCCTCTGAGCAGCGTCTCCTCTCTGGAGGTCCACTTCGACCTCCTGGACCTCACTGAGCTC
ACCGACATGTCGGACCAGGAGCTGGCCGAGGTCTTTGCTGACTCGGACGACGAGAACCTCAACACCGAGTCCCCAGCAGCCGAGAAGGTG
AGCTCCCTGGGGAAGGACTGGCACAAGTTCTGCCTCAAGTGCGAGCGCTGCAGCAAGACGCTGACGCCCGGGGGCCACGCCGAGCATGAC
GGGAAGCCGTTCTGCCACAAGCCGTGCTACGCCACCCTGTTCGGACCCAAAGGCGTGAACATCGGGGGCGCGGGCTCCTACATCTACGAG
AAGCCCCTGGCGGAGGGGCCGCAGGTCACCGGCCCCATCGAGGTCCCCGCGGCCCGAGCAGAGGAGCGGAAGGCGAGCGGCCCCCCGAAG
GGGCCCAGCAGAGCCTCCAGTGTCACCACTTTCACCGGGGAGCCCAACACGTGCCCGCGCTGCAGCAAGAAGGTGTACTTCGCTGAGAAG
GTGACGTCTCTGGGCAAGGATTGGCACCGGCCCTGCCTGCGCTGCGAGCGCTGCGGGAAGACACTGACCCCCGGCGGGCACGCGGAGCAC
GACGGCCAGCCCTACTGCCACAAGCCCTGCTATGGAATCCTCTTCGGACCCAAGGGAGTGAACACCGGTGCGGTGGGCAGCTACATCTAT
GACCGGGACCCCGAAGGCAAGGTCCAGCCCTAGGCTACAGCGGCTCTCATGATGTGGGCTCACCTGCGCCCCAG

>21449_21449_6_DBNDD1-CRIP2_DBNDD1_chr16_90075192_ENST00000392973_CRIP2_chr14_105944603_ENST00000483017_length(amino acids)=352AA_BP=279
MKPLNPLSGSRHEATSPAIPSPAGHCPEFQRTGCAKSSHPAPRPGGMWEPCGSQGDTVSLDAEIVKEAEVPQAALGVPAQGTGDNGHTPV
EEEVGGIPVPAPGLLQVTERRQPLSSVSSLEVHFDLLDLTELTDMSDQELAEVFADSDDENLNTESPAAEKVSSLGKDWHKFCLKCERCS
KTLTPGGHAEHDGKPFCHKPCYATLFGPKGVNIGGAGSYIYEKPLAEGPQVTGPIEVPAARAEERKASGPPKGPSRASSVTTFTGEPNTC
PRCSKKVYFAEKVTSLGKDWHRPCLRCERCGKTLTPGGHAEHDGQPYCHKPCYGILFGPKGVNTGAVGSYIYDRDPEGKVQP

--------------------------------------------------------------
>21449_21449_7_DBNDD1-CRIP2_DBNDD1_chr16_90075192_ENST00000568838_CRIP2_chr14_105944603_ENST00000329146_length(transcript)=1782nt_BP=689nt
TTGCTTCAAAATGACCCAGCAGTGGAGGGAAGTGAATGAGGACAGAGAAGCAGTGGCCCAGGCCAGGAGCTGGCAATCGCTGAATCTGGG
CGATAGGGACATGGGGGTCAGTTTCATCGAAACTGCCTTGGCGCTCTCTGCAGCCCGGGCCCGCCGCCCTCTCCTTACCTCCCATCCCCC
ATCCCGCCCCTTCCAGCCTCCCAAGCACACGCCCTCGCCCCCACCCGCCCCCCGCGTTAATTCGCGCCATCCAGGGCGCTCTGTGAGTCT
GTCATTACCCAGCGCGAGTCAGGCCCCTCCTGTGCCCCTCGCCAGCCCCGAGGGGCGCCCGCACACAGTCGGCGCCCCACACGCAAGTAC
CTGGAAGAGAACAAGAGGACGCCAGCGGGCGCGGCCGCCAAAGATCGTTAAGGAGGCTGAGGTGCCGCAGGCTGCGCTGGGCGTCCCAGC
CCAGGGGACAGGGGACAATGGCCACACGCCTGTGGAGGAGGAGGTCGGGGGCATCCCAGTACCAGCACCGGGGCTCCTGCAGGTCACGGA
GAGGAGGCAGCCTCTGAGCAGCGTCTCCTCTCTGGAGGTCCACTTCGACCTCCTGGACCTCACTGAGCTCACCGACATGTCGGACCAGGA
GCTGGCCGAGGTCTTTGCTGACTCGGACGACGAGAACCTCAACACCGAGTCCCCAGCAGCCGAGAAGGTGAGCTCCCTGGGGAAGGACTG
GCACAAGTTCTGCCTCAAGTGCGAGCGCTGCAGCAAGACGCTGACGCCCGGGGGCCACGCCGAGCATGACGGGAAGCCGTTCTGCCACAA
GCCGTGCTACGCCACCCTGTTCGGACCCAAAGGCGTGAACATCGGGGGCGCGGGCTCCTACATCTACGAGAAGCCCCTGGCGGAGGGGCC
GCAGGTCACCGGCCCCATCGAGGTCCCCGCGGCCCGAGCAGAGGAGCGGAAGGCGAGCGGCCCCCCGAAGGGGCCCAGCAGAGCCTCCAG
TGTCACCACTTTCACCGGGGAGCCCAACACGTGCCCGCGCTGCAGCAAGAAGGTGTACTTCGCTGAGAAGGTGACGTCTCTGGGCAAGGA
TTGGCACCGGCCCTGCCTGCGCTGCGAGCGCTGCGGGAAGACACTGACCCCCGGCGGGCACGCGGAGCACGACGGCCAGCCCTACTGCCA
CAAGCCCTGCTATGGAATCCTCTTCGGACCCAAGGGAGTGAACACCGGTGCGGTGGGCAGCTACATCTATGACCGGGACCCCGAAGGCAA
GGTCCAGCCCTAGGCTACAGCGGCTCTCATGATGTGGGCTCACCTGCGCCCCAGACCCTGCAGGGGCCCCCCTGCTTGGCTCTGCTGGGA
GAGTGCTCAGCCGCCCAGTCCTGCCTGCAAGCCCAGGGCGAGTATTGGAGGAGGGGCAGCCACGGGCAGAGCACCATGCCCATCCCCGAG
TCTCTGGTGTGTCTGCCCCCTCTGGCATCCTCTGGGCGTCCCATGATCCCTTCTGTGTCTGCGTGTCCGAATCCCCGTGTGACCCTGTCC
CAGCATTTTCCCGCCGACCCTGCGTGTCCCCGTGGCGCTGTCCGCTCTCCCTCTCCTGCTGCCCACCCACCTGCCAGTGTTATTTATGCT
CCCTTCGTGGGTGATGGCCACGCCCTCACCATGTCCCTGGCAGAGGGCTTCCCTCCGGGATCCCCTGCCTGGTGCCCACACTGCCTCGCA
AGCGCTCGCCACCCTCACGTGGCTCACCTGCTGTTGAGCCTTGTGCTGTCAATAAACGGTTTGAGGATTGCA

>21449_21449_7_DBNDD1-CRIP2_DBNDD1_chr16_90075192_ENST00000568838_CRIP2_chr14_105944603_ENST00000329146_length(amino acids)=420AA_BP=347
MTQQWREVNEDREAVAQARSWQSLNLGDRDMGVSFIETALALSAARARRPLLTSHPPSRPFQPPKHTPSPPPAPRVNSRHPGRSVSLSLP
SASQAPPVPLASPEGRPHTVGAPHASTWKRTRGRQRARPPKIVKEAEVPQAALGVPAQGTGDNGHTPVEEEVGGIPVPAPGLLQVTERRQ
PLSSVSSLEVHFDLLDLTELTDMSDQELAEVFADSDDENLNTESPAAEKVSSLGKDWHKFCLKCERCSKTLTPGGHAEHDGKPFCHKPCY
ATLFGPKGVNIGGAGSYIYEKPLAEGPQVTGPIEVPAARAEERKASGPPKGPSRASSVTTFTGEPNTCPRCSKKVYFAEKVTSLGKDWHR
PCLRCERCGKTLTPGGHAEHDGQPYCHKPCYGILFGPKGVNTGAVGSYIYDRDPEGKVQP

--------------------------------------------------------------
>21449_21449_8_DBNDD1-CRIP2_DBNDD1_chr16_90075192_ENST00000568838_CRIP2_chr14_105944603_ENST00000483017_length(transcript)=1314nt_BP=689nt
TTGCTTCAAAATGACCCAGCAGTGGAGGGAAGTGAATGAGGACAGAGAAGCAGTGGCCCAGGCCAGGAGCTGGCAATCGCTGAATCTGGG
CGATAGGGACATGGGGGTCAGTTTCATCGAAACTGCCTTGGCGCTCTCTGCAGCCCGGGCCCGCCGCCCTCTCCTTACCTCCCATCCCCC
ATCCCGCCCCTTCCAGCCTCCCAAGCACACGCCCTCGCCCCCACCCGCCCCCCGCGTTAATTCGCGCCATCCAGGGCGCTCTGTGAGTCT
GTCATTACCCAGCGCGAGTCAGGCCCCTCCTGTGCCCCTCGCCAGCCCCGAGGGGCGCCCGCACACAGTCGGCGCCCCACACGCAAGTAC
CTGGAAGAGAACAAGAGGACGCCAGCGGGCGCGGCCGCCAAAGATCGTTAAGGAGGCTGAGGTGCCGCAGGCTGCGCTGGGCGTCCCAGC
CCAGGGGACAGGGGACAATGGCCACACGCCTGTGGAGGAGGAGGTCGGGGGCATCCCAGTACCAGCACCGGGGCTCCTGCAGGTCACGGA
GAGGAGGCAGCCTCTGAGCAGCGTCTCCTCTCTGGAGGTCCACTTCGACCTCCTGGACCTCACTGAGCTCACCGACATGTCGGACCAGGA
GCTGGCCGAGGTCTTTGCTGACTCGGACGACGAGAACCTCAACACCGAGTCCCCAGCAGCCGAGAAGGTGAGCTCCCTGGGGAAGGACTG
GCACAAGTTCTGCCTCAAGTGCGAGCGCTGCAGCAAGACGCTGACGCCCGGGGGCCACGCCGAGCATGACGGGAAGCCGTTCTGCCACAA
GCCGTGCTACGCCACCCTGTTCGGACCCAAAGGCGTGAACATCGGGGGCGCGGGCTCCTACATCTACGAGAAGCCCCTGGCGGAGGGGCC
GCAGGTCACCGGCCCCATCGAGGTCCCCGCGGCCCGAGCAGAGGAGCGGAAGGCGAGCGGCCCCCCGAAGGGGCCCAGCAGAGCCTCCAG
TGTCACCACTTTCACCGGGGAGCCCAACACGTGCCCGCGCTGCAGCAAGAAGGTGTACTTCGCTGAGAAGGTGACGTCTCTGGGCAAGGA
TTGGCACCGGCCCTGCCTGCGCTGCGAGCGCTGCGGGAAGACACTGACCCCCGGCGGGCACGCGGAGCACGACGGCCAGCCCTACTGCCA
CAAGCCCTGCTATGGAATCCTCTTCGGACCCAAGGGAGTGAACACCGGTGCGGTGGGCAGCTACATCTATGACCGGGACCCCGAAGGCAA
GGTCCAGCCCTAGGCTACAGCGGCTCTCATGATGTGGGCTCACCTGCGCCCCAG

>21449_21449_8_DBNDD1-CRIP2_DBNDD1_chr16_90075192_ENST00000568838_CRIP2_chr14_105944603_ENST00000483017_length(amino acids)=420AA_BP=347
MTQQWREVNEDREAVAQARSWQSLNLGDRDMGVSFIETALALSAARARRPLLTSHPPSRPFQPPKHTPSPPPAPRVNSRHPGRSVSLSLP
SASQAPPVPLASPEGRPHTVGAPHASTWKRTRGRQRARPPKIVKEAEVPQAALGVPAQGTGDNGHTPVEEEVGGIPVPAPGLLQVTERRQ
PLSSVSSLEVHFDLLDLTELTDMSDQELAEVFADSDDENLNTESPAAEKVSSLGKDWHKFCLKCERCSKTLTPGGHAEHDGKPFCHKPCY
ATLFGPKGVNIGGAGSYIYEKPLAEGPQVTGPIEVPAARAEERKASGPPKGPSRASSVTTFTGEPNTCPRCSKKVYFAEKVTSLGKDWHR
PCLRCERCGKTLTPGGHAEHDGQPYCHKPCYGILFGPKGVNTGAVGSYIYDRDPEGKVQP

--------------------------------------------------------------

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Fusion Gene PPI Analysis for DBNDD1-CRIP2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for DBNDD1-CRIP2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for DBNDD1-CRIP2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource