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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:ATAT1-HCG20 (FusionGDB2 ID:HG79969TG105375013)

Fusion Gene Summary for ATAT1-HCG20

Fusion gene summary

Fusion gene information	Fusion gene name: ATAT1-HCG20
	Fusion gene ID: hg79969tg105375013
		Hgene	Tgene
	Gene symbol	ATAT1	HCG20
	Gene ID	79969	105375013
	Gene name	alpha tubulin acetyltransferase 1	HLA complex group 20
	Synonyms	C6orf134\|MEC17\|Nbla00487\|TAT\|alpha-TAT\|alpha-TAT1	NCRNA00149
	Cytomap	('ATAT1')('HCG20') 6p21.33	6p21.33
	Type of gene	protein-coding	ncRNA
	Description	alpha-tubulin N-acetyltransferase 1acetyltransferase mec-17 homolog	HLA complex group 20 (non-protein coding)
	Modification date	20200313	20200313
	UniProtAcc	.	.
	Ensembl transtripts involved in fusion gene	ENST00000468713, ENST00000318999, ENST00000319027, ENST00000329992, ENST00000330083, ENST00000376478, ENST00000376483, ENST00000376485, ENST00000383582, ENST00000383584, ENST00000383585, ENST00000400575, ENST00000400576, ENST00000411724, ENST00000416435, ENST00000416917, ENST00000417183, ENST00000418248, ENST00000420586, ENST00000423338, ENST00000423654, ENST00000424121, ENST00000425448, ENST00000428764, ENST00000430611, ENST00000432356, ENST00000432643, ENST00000442844, ENST00000443114, ENST00000443391, ENST00000445486, ENST00000445973, ENST00000446100, ENST00000448670, ENST00000449905, ENST00000450003, ENST00000450220, ENST00000454794, ENST00000454987, ENST00000456215, ENST00000456704, ENST00000457161, ENST00000457334, ENST00000472552, ENST00000477838, ENST00000479580, ENST00000481303, ENST00000489189, ENST00000490845, ENST00000546440, ENST00000547124, ENST00000550031, ENST00000551737, ENST00000553018, ENST00000553093,
Fusion gene scores	* DoF score	4 X 3 X 3=36	1 X 1 X 1=1
	# samples	4	1
	** MAII score	log2(4/36*10)=0.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0	log2(1/1*10)=3.32192809488736
Context	PubMed: ATAT1 [Title/Abstract] AND HCG20 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	ATAT1(30596207)-HCG20(30756468), # samples:2
Anticipated loss of major functional domain due to fusion event.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	ATAT1	GO:0071929	alpha-tubulin acetylation	23071314\|24906155

Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	OV	TCGA-61-1910-01A	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+

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Fusion Gene ORF analysis for ATAT1-HCG20

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
3UTR-3UTR	ENST00000468713	ENST00000439406	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
3UTR-intron	ENST00000468713	ENST00000413396	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
3UTR-intron	ENST00000468713	ENST00000417629	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
3UTR-intron	ENST00000468713	ENST00000423317	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
3UTR-intron	ENST00000468713	ENST00000431949	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
3UTR-intron	ENST00000468713	ENST00000437931	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
5CDS-3UTR	ENST00000318999	ENST00000439406	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
5CDS-3UTR	ENST00000319027	ENST00000439406	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
5CDS-3UTR	ENST00000329992	ENST00000439406	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
5CDS-3UTR	ENST00000330083	ENST00000439406	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
5CDS-3UTR	ENST00000376478	ENST00000439406	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
5CDS-3UTR	ENST00000376483	ENST00000439406	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
5CDS-3UTR	ENST00000376485	ENST00000439406	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
5CDS-intron	ENST00000318999	ENST00000413396	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
5CDS-intron	ENST00000318999	ENST00000417629	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
5CDS-intron	ENST00000318999	ENST00000423317	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
5CDS-intron	ENST00000318999	ENST00000431949	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
5CDS-intron	ENST00000318999	ENST00000437931	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
5CDS-intron	ENST00000319027	ENST00000413396	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
5CDS-intron	ENST00000319027	ENST00000417629	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
5CDS-intron	ENST00000319027	ENST00000423317	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
5CDS-intron	ENST00000319027	ENST00000431949	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
5CDS-intron	ENST00000319027	ENST00000437931	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
5CDS-intron	ENST00000329992	ENST00000413396	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
5CDS-intron	ENST00000329992	ENST00000417629	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
5CDS-intron	ENST00000329992	ENST00000423317	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
5CDS-intron	ENST00000329992	ENST00000431949	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
5CDS-intron	ENST00000329992	ENST00000437931	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
5CDS-intron	ENST00000330083	ENST00000413396	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
5CDS-intron	ENST00000330083	ENST00000417629	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
5CDS-intron	ENST00000330083	ENST00000423317	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
5CDS-intron	ENST00000330083	ENST00000431949	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
5CDS-intron	ENST00000330083	ENST00000437931	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
5CDS-intron	ENST00000376478	ENST00000413396	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
5CDS-intron	ENST00000376478	ENST00000417629	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
5CDS-intron	ENST00000376478	ENST00000423317	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
5CDS-intron	ENST00000376478	ENST00000431949	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
5CDS-intron	ENST00000376478	ENST00000437931	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
5CDS-intron	ENST00000376483	ENST00000413396	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
5CDS-intron	ENST00000376483	ENST00000417629	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
5CDS-intron	ENST00000376483	ENST00000423317	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
5CDS-intron	ENST00000376483	ENST00000431949	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
5CDS-intron	ENST00000376483	ENST00000437931	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
5CDS-intron	ENST00000376485	ENST00000413396	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
5CDS-intron	ENST00000376485	ENST00000417629	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
5CDS-intron	ENST00000376485	ENST00000423317	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
5CDS-intron	ENST00000376485	ENST00000431949	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
5CDS-intron	ENST00000376485	ENST00000437931	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-3UTR	ENST00000383582	ENST00000439406	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-3UTR	ENST00000383584	ENST00000439406	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-3UTR	ENST00000383585	ENST00000439406	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-3UTR	ENST00000400575	ENST00000439406	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-3UTR	ENST00000400576	ENST00000439406	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-3UTR	ENST00000411724	ENST00000439406	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-3UTR	ENST00000416435	ENST00000439406	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-3UTR	ENST00000416917	ENST00000439406	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-3UTR	ENST00000417183	ENST00000439406	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-3UTR	ENST00000418248	ENST00000439406	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-3UTR	ENST00000420586	ENST00000439406	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-3UTR	ENST00000423338	ENST00000439406	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-3UTR	ENST00000423654	ENST00000439406	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-3UTR	ENST00000424121	ENST00000439406	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-3UTR	ENST00000425448	ENST00000439406	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-3UTR	ENST00000428764	ENST00000439406	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-3UTR	ENST00000430611	ENST00000439406	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-3UTR	ENST00000432356	ENST00000439406	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-3UTR	ENST00000432643	ENST00000439406	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-3UTR	ENST00000442844	ENST00000439406	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-3UTR	ENST00000443114	ENST00000439406	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-3UTR	ENST00000443391	ENST00000439406	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-3UTR	ENST00000445486	ENST00000439406	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-3UTR	ENST00000445973	ENST00000439406	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-3UTR	ENST00000446100	ENST00000439406	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-3UTR	ENST00000448670	ENST00000439406	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-3UTR	ENST00000449905	ENST00000439406	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-3UTR	ENST00000450003	ENST00000439406	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-3UTR	ENST00000450220	ENST00000439406	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-3UTR	ENST00000454794	ENST00000439406	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-3UTR	ENST00000454987	ENST00000439406	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-3UTR	ENST00000456215	ENST00000439406	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-3UTR	ENST00000456704	ENST00000439406	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-3UTR	ENST00000457161	ENST00000439406	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-3UTR	ENST00000457334	ENST00000439406	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-3UTR	ENST00000472552	ENST00000439406	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-3UTR	ENST00000477838	ENST00000439406	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-3UTR	ENST00000479580	ENST00000439406	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-3UTR	ENST00000481303	ENST00000439406	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-3UTR	ENST00000489189	ENST00000439406	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-3UTR	ENST00000490845	ENST00000439406	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-3UTR	ENST00000546440	ENST00000439406	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-3UTR	ENST00000547124	ENST00000439406	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-3UTR	ENST00000550031	ENST00000439406	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-3UTR	ENST00000551737	ENST00000439406	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-3UTR	ENST00000553018	ENST00000439406	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-3UTR	ENST00000553093	ENST00000439406	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000383582	ENST00000413396	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000383582	ENST00000417629	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000383582	ENST00000423317	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000383582	ENST00000431949	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000383582	ENST00000437931	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000383584	ENST00000413396	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000383584	ENST00000417629	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000383584	ENST00000423317	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000383584	ENST00000431949	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000383584	ENST00000437931	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000383585	ENST00000413396	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000383585	ENST00000417629	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000383585	ENST00000423317	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000383585	ENST00000431949	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000383585	ENST00000437931	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000400575	ENST00000413396	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000400575	ENST00000417629	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000400575	ENST00000423317	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000400575	ENST00000431949	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000400575	ENST00000437931	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000400576	ENST00000413396	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000400576	ENST00000417629	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000400576	ENST00000423317	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000400576	ENST00000431949	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000400576	ENST00000437931	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000411724	ENST00000413396	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000411724	ENST00000417629	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000411724	ENST00000423317	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000411724	ENST00000431949	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000411724	ENST00000437931	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000416435	ENST00000413396	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000416435	ENST00000417629	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000416435	ENST00000423317	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000416435	ENST00000431949	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000416435	ENST00000437931	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000416917	ENST00000413396	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000416917	ENST00000417629	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000416917	ENST00000423317	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000416917	ENST00000431949	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000416917	ENST00000437931	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000417183	ENST00000413396	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000417183	ENST00000417629	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000417183	ENST00000423317	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000417183	ENST00000431949	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000417183	ENST00000437931	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000418248	ENST00000413396	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000418248	ENST00000417629	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000418248	ENST00000423317	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000418248	ENST00000431949	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000418248	ENST00000437931	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000420586	ENST00000413396	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000420586	ENST00000417629	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000420586	ENST00000423317	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000420586	ENST00000431949	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000420586	ENST00000437931	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000423338	ENST00000413396	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000423338	ENST00000417629	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000423338	ENST00000423317	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000423338	ENST00000431949	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000423338	ENST00000437931	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000423654	ENST00000413396	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000423654	ENST00000417629	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000423654	ENST00000423317	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000423654	ENST00000431949	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000423654	ENST00000437931	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000424121	ENST00000413396	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000424121	ENST00000417629	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000424121	ENST00000423317	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000424121	ENST00000431949	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000424121	ENST00000437931	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000425448	ENST00000413396	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000425448	ENST00000417629	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000425448	ENST00000423317	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000425448	ENST00000431949	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000425448	ENST00000437931	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000428764	ENST00000413396	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000428764	ENST00000417629	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000428764	ENST00000423317	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000428764	ENST00000431949	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000428764	ENST00000437931	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000430611	ENST00000413396	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000430611	ENST00000417629	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000430611	ENST00000423317	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000430611	ENST00000431949	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000430611	ENST00000437931	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000432356	ENST00000413396	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000432356	ENST00000417629	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000432356	ENST00000423317	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000432356	ENST00000431949	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000432356	ENST00000437931	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000432643	ENST00000413396	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000432643	ENST00000417629	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000432643	ENST00000423317	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000432643	ENST00000431949	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000432643	ENST00000437931	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000442844	ENST00000413396	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000442844	ENST00000417629	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000442844	ENST00000423317	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000442844	ENST00000431949	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000442844	ENST00000437931	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000443114	ENST00000413396	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000443114	ENST00000417629	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000443114	ENST00000423317	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000443114	ENST00000431949	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000443114	ENST00000437931	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000443391	ENST00000413396	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000443391	ENST00000417629	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000443391	ENST00000423317	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000443391	ENST00000431949	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000443391	ENST00000437931	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000445486	ENST00000413396	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000445486	ENST00000417629	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000445486	ENST00000423317	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000445486	ENST00000431949	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000445486	ENST00000437931	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000445973	ENST00000413396	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000445973	ENST00000417629	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000445973	ENST00000423317	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000445973	ENST00000431949	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000445973	ENST00000437931	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000446100	ENST00000413396	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000446100	ENST00000417629	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000446100	ENST00000423317	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000446100	ENST00000431949	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000446100	ENST00000437931	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000448670	ENST00000413396	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000448670	ENST00000417629	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000448670	ENST00000423317	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000448670	ENST00000431949	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000448670	ENST00000437931	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000449905	ENST00000413396	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000449905	ENST00000417629	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000449905	ENST00000423317	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000449905	ENST00000431949	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000449905	ENST00000437931	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000450003	ENST00000413396	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000450003	ENST00000417629	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000450003	ENST00000423317	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000450003	ENST00000431949	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000450003	ENST00000437931	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000450220	ENST00000413396	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000450220	ENST00000417629	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000450220	ENST00000423317	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000450220	ENST00000431949	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000450220	ENST00000437931	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000454794	ENST00000413396	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000454794	ENST00000417629	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000454794	ENST00000423317	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000454794	ENST00000431949	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000454794	ENST00000437931	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000454987	ENST00000413396	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000454987	ENST00000417629	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000454987	ENST00000423317	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000454987	ENST00000431949	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000454987	ENST00000437931	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000456215	ENST00000413396	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000456215	ENST00000417629	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000456215	ENST00000423317	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000456215	ENST00000431949	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000456215	ENST00000437931	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000456704	ENST00000413396	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000456704	ENST00000417629	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000456704	ENST00000423317	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000456704	ENST00000431949	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000456704	ENST00000437931	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000457161	ENST00000413396	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000457161	ENST00000417629	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000457161	ENST00000423317	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000457161	ENST00000431949	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000457161	ENST00000437931	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000457334	ENST00000413396	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000457334	ENST00000417629	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000457334	ENST00000423317	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000457334	ENST00000431949	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000457334	ENST00000437931	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000472552	ENST00000413396	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000472552	ENST00000417629	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000472552	ENST00000423317	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000472552	ENST00000431949	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000472552	ENST00000437931	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000477838	ENST00000413396	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000477838	ENST00000417629	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000477838	ENST00000423317	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000477838	ENST00000431949	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000477838	ENST00000437931	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000479580	ENST00000413396	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000479580	ENST00000417629	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000479580	ENST00000423317	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000479580	ENST00000431949	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000479580	ENST00000437931	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000481303	ENST00000413396	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000481303	ENST00000417629	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000481303	ENST00000423317	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000481303	ENST00000431949	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000481303	ENST00000437931	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000489189	ENST00000413396	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000489189	ENST00000417629	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000489189	ENST00000423317	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000489189	ENST00000431949	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000489189	ENST00000437931	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000490845	ENST00000413396	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000490845	ENST00000417629	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000490845	ENST00000423317	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000490845	ENST00000431949	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000490845	ENST00000437931	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000546440	ENST00000413396	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000546440	ENST00000417629	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000546440	ENST00000423317	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000546440	ENST00000431949	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000546440	ENST00000437931	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000547124	ENST00000413396	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000547124	ENST00000417629	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000547124	ENST00000423317	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000547124	ENST00000431949	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000547124	ENST00000437931	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000550031	ENST00000413396	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000550031	ENST00000417629	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000550031	ENST00000423317	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000550031	ENST00000431949	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000550031	ENST00000437931	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000551737	ENST00000413396	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000551737	ENST00000417629	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000551737	ENST00000423317	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000551737	ENST00000431949	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000551737	ENST00000437931	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000553018	ENST00000413396	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000553018	ENST00000417629	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000553018	ENST00000423317	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000553018	ENST00000431949	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000553018	ENST00000437931	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000553093	ENST00000413396	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000553093	ENST00000417629	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000553093	ENST00000423317	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000553093	ENST00000431949	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+
intron-intron	ENST00000553093	ENST00000437931	ATAT1	chr6	30596207	+	HCG20	chr6	30756468	+

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst

Tenst

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

Seq length
(transcript)

BP loci
(transcript)

Predicted start
(transcript)

Predicted stop
(transcript)

Seq length
(amino acids)

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst

Tenst

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

No-coding score

Coding score

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Fusion Genomic Features for ATAT1-HCG20

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	1-p	p (fusion gene breakpoint)
ATAT1	chr6	30596207	+	HCG20	chr6	30756467	+	9.34E-09	1
ATAT1	chr6	30596207	+	HCG20	chr6	30756467	+	9.34E-09	1

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for ATAT1-HCG20

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/:30596207/:30756468)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	.
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.	FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

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Fusion Gene Sequence for ATAT1-HCG20

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

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Fusion Gene PPI Analysis for ATAT1-HCG20

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

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Related Drugs for ATAT1-HCG20

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for ATAT1-HCG20

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner	Gene	Disease ID	Disease name	# pubmeds	Source
Hgene	ATAT1	C2931456	Prostate cancer, familial	1	CTD_human
Hgene	ATAT1	C4722327	PROSTATE CANCER, HEREDITARY, 1	1	CTD_human

Fusion Gene Studies in Kim Lab

Fusion gene:ATAT1-HCG20 (FusionGDB2 ID:HG79969TG105375013)

Fusion Gene Summary for ATAT1-HCG20

Fusion Gene ORF analysis for ATAT1-HCG20

Fusion Genomic Features for ATAT1-HCG20

Fusion Protein Features for ATAT1-HCG20

Fusion Gene Sequence for ATAT1-HCG20

Fusion Gene PPI Analysis for ATAT1-HCG20

Related Drugs for ATAT1-HCG20

Related Diseases for ATAT1-HCG20

Fusion Gene Studies
in Kim Lab