Fusion Gene Studies
in Kim Lab

FusionBase FusionGDB FusionGDB2 FusionPDB FusionNeoAntigen FusionAI FusionNW FGviewer Publication Contact
FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:ARHGAP39-ZNF16 (FusionGDB2 ID:HG80728TG7564)

Fusion Gene Summary for ARHGAP39-ZNF16

check button Fusion gene summary
Fusion gene informationFusion gene name: ARHGAP39-ZNF16
Fusion gene ID: hg80728tg7564
HgeneTgene
Gene symbol

ARHGAP39

ZNF16

Gene ID

80728

7564

Gene nameRho GTPase activating protein 39zinc finger protein 16
SynonymsCrGAP|VilseHZF1|KOX9
Cytomap('ARHGAP39')('ZNF16')

8q24.3

8q24.3

Type of geneprotein-codingprotein-coding
Descriptionrho GTPase-activating protein 39RhoGAP93B homologcrossGAP homologzinc finger protein 16zinc finger protein KOX9zinc finger protein Kruppel type 9
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000528810, ENST00000276826, 
ENST00000377307, ENST00000540274, 
Fusion gene scores* DoF score9 X 7 X 5=3152 X 2 X 2=8
# samples 82
** MAII scorelog2(8/315*10)=-1.97727992349992
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(2/8*10)=1.32192809488736
Context

PubMed: ARHGAP39 [Title/Abstract] AND ZNF16 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointARHGAP39(145770633)-ZNF16(146157976), # samples:3
Anticipated loss of major functional domain due to fusion event.ARHGAP39-ZNF16 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ARHGAP39-ZNF16 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ARHGAP39-ZNF16 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
ARHGAP39-ZNF16 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
ARHGAP39-ZNF16 seems lost the major protein functional domain in Tgene partner, which is a transcription factor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneARHGAP39

GO:0099173

postsynapse organization

24656827

TgeneZNF16

GO:0008284

positive regulation of cell proliferation

21874239

TgeneZNF16

GO:0033674

positive regulation of kinase activity

21874239

TgeneZNF16

GO:0043066

negative regulation of apoptotic process

21874239

TgeneZNF16

GO:0072707

cellular response to sodium dodecyl sulfate

21874239

TgeneZNF16

GO:1901989

positive regulation of cell cycle phase transition

21874239


check buttonFusion gene breakpoints across ARHGAP39 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across ZNF16 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-BR-7716-01AARHGAP39chr8

145770633

-ZNF16chr8

146157976

-
ChimerDB4STADTCGA-BR-7716-01AARHGAP39chr8

145780944

-ZNF16chr8

146157976

-


Top

Fusion Gene ORF analysis for ARHGAP39-ZNF16

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5UTR-3CDSENST00000528810ENST00000276816ARHGAP39chr8

145770633

-ZNF16chr8

146157976

-
5UTR-3CDSENST00000528810ENST00000394909ARHGAP39chr8

145770633

-ZNF16chr8

146157976

-
Frame-shiftENST00000276826ENST00000276816ARHGAP39chr8

145770633

-ZNF16chr8

146157976

-
Frame-shiftENST00000276826ENST00000276816ARHGAP39chr8

145780944

-ZNF16chr8

146157976

-
Frame-shiftENST00000276826ENST00000394909ARHGAP39chr8

145770633

-ZNF16chr8

146157976

-
Frame-shiftENST00000276826ENST00000394909ARHGAP39chr8

145780944

-ZNF16chr8

146157976

-
Frame-shiftENST00000377307ENST00000276816ARHGAP39chr8

145770633

-ZNF16chr8

146157976

-
Frame-shiftENST00000377307ENST00000276816ARHGAP39chr8

145780944

-ZNF16chr8

146157976

-
Frame-shiftENST00000377307ENST00000394909ARHGAP39chr8

145770633

-ZNF16chr8

146157976

-
Frame-shiftENST00000377307ENST00000394909ARHGAP39chr8

145780944

-ZNF16chr8

146157976

-
Frame-shiftENST00000540274ENST00000276816ARHGAP39chr8

145780944

-ZNF16chr8

146157976

-
Frame-shiftENST00000540274ENST00000394909ARHGAP39chr8

145780944

-ZNF16chr8

146157976

-
In-frameENST00000540274ENST00000276816ARHGAP39chr8

145770633

-ZNF16chr8

146157976

-
In-frameENST00000540274ENST00000394909ARHGAP39chr8

145770633

-ZNF16chr8

146157976

-
intron-3CDSENST00000528810ENST00000276816ARHGAP39chr8

145780944

-ZNF16chr8

146157976

-
intron-3CDSENST00000528810ENST00000394909ARHGAP39chr8

145780944

-ZNF16chr8

146157976

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000540274ARHGAP39chr8145770633-ENST00000276816ZNF16chr8146157976-4959272617545781467
ENST00000540274ARHGAP39chr8145770633-ENST00000394909ZNF16chr8146157976-4932272617545781467

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000540274ENST00000276816ARHGAP39chr8145770633-ZNF16chr8146157976-0.0026980690.99730194
ENST00000540274ENST00000394909ARHGAP39chr8145770633-ZNF16chr8146157976-0.0028726030.99712735

Top

Fusion Genomic Features for ARHGAP39-ZNF16


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

Top

Fusion Protein Features for ARHGAP39-ZNF16


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr8:145770633/chr8:146157976)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneARHGAP39chr8:145770633chr8:146157976ENST00000276826-510234_3678401084.0Compositional biasNote=Pro-rich
HgeneARHGAP39chr8:145770633chr8:146157976ENST00000377307-511234_3678401115.0Compositional biasNote=Pro-rich
HgeneARHGAP39chr8:145770633chr8:146157976ENST00000540274-611234_3678401084.0Compositional biasNote=Pro-rich
HgeneARHGAP39chr8:145770633chr8:146157976ENST00000276826-51025_588401084.0DomainWW 1
HgeneARHGAP39chr8:145770633chr8:146157976ENST00000276826-51063_978401084.0DomainWW 2
HgeneARHGAP39chr8:145770633chr8:146157976ENST00000377307-51125_588401115.0DomainWW 1
HgeneARHGAP39chr8:145770633chr8:146157976ENST00000377307-51163_978401115.0DomainWW 2
HgeneARHGAP39chr8:145770633chr8:146157976ENST00000540274-61125_588401084.0DomainWW 1
HgeneARHGAP39chr8:145770633chr8:146157976ENST00000540274-61163_978401084.0DomainWW 2
TgeneZNF16chr8:145770633chr8:146157976ENST0000027681624268_39365683.0RegionNote=Required for nuclear localization
TgeneZNF16chr8:145770633chr8:146157976ENST0000027681624341_37365683.0RegionNote=Required for nuclear localization
TgeneZNF16chr8:145770633chr8:146157976ENST0000027681624473_50365683.0RegionNote=Required for nuclear localization
TgeneZNF16chr8:145770633chr8:146157976ENST0000039490913268_39365683.0RegionNote=Required for nuclear localization
TgeneZNF16chr8:145770633chr8:146157976ENST0000039490913341_37365683.0RegionNote=Required for nuclear localization
TgeneZNF16chr8:145770633chr8:146157976ENST0000039490913473_50365683.0RegionNote=Required for nuclear localization
TgeneZNF16chr8:145770633chr8:146157976ENST0000027681624209_23165683.0Zinc fingerC2H2-type 1%3B degenerate
TgeneZNF16chr8:145770633chr8:146157976ENST0000027681624237_25965683.0Zinc fingerC2H2-type 2%3B degenerate
TgeneZNF16chr8:145770633chr8:146157976ENST0000027681624265_28765683.0Zinc fingerC2H2-type 3
TgeneZNF16chr8:145770633chr8:146157976ENST0000027681624293_31565683.0Zinc fingerC2H2-type 4
TgeneZNF16chr8:145770633chr8:146157976ENST0000027681624321_34365683.0Zinc fingerC2H2-type 5
TgeneZNF16chr8:145770633chr8:146157976ENST0000027681624349_37165683.0Zinc fingerC2H2-type 6
TgeneZNF16chr8:145770633chr8:146157976ENST0000027681624377_39965683.0Zinc fingerC2H2-type 7
TgeneZNF16chr8:145770633chr8:146157976ENST0000027681624405_42765683.0Zinc fingerC2H2-type 8
TgeneZNF16chr8:145770633chr8:146157976ENST0000027681624433_45565683.0Zinc fingerC2H2-type 9
TgeneZNF16chr8:145770633chr8:146157976ENST0000027681624461_48365683.0Zinc fingerC2H2-type 10
TgeneZNF16chr8:145770633chr8:146157976ENST0000027681624489_51165683.0Zinc fingerC2H2-type 11
TgeneZNF16chr8:145770633chr8:146157976ENST0000027681624517_53965683.0Zinc fingerC2H2-type 12
TgeneZNF16chr8:145770633chr8:146157976ENST0000027681624545_56765683.0Zinc fingerC2H2-type 13
TgeneZNF16chr8:145770633chr8:146157976ENST0000027681624573_59565683.0Zinc fingerC2H2-type 14
TgeneZNF16chr8:145770633chr8:146157976ENST0000027681624601_62365683.0Zinc fingerC2H2-type 15
TgeneZNF16chr8:145770633chr8:146157976ENST0000027681624629_65165683.0Zinc fingerC2H2-type 16
TgeneZNF16chr8:145770633chr8:146157976ENST0000027681624657_67965683.0Zinc fingerC2H2-type 17
TgeneZNF16chr8:145770633chr8:146157976ENST0000039490913209_23165683.0Zinc fingerC2H2-type 1%3B degenerate
TgeneZNF16chr8:145770633chr8:146157976ENST0000039490913237_25965683.0Zinc fingerC2H2-type 2%3B degenerate
TgeneZNF16chr8:145770633chr8:146157976ENST0000039490913265_28765683.0Zinc fingerC2H2-type 3
TgeneZNF16chr8:145770633chr8:146157976ENST0000039490913293_31565683.0Zinc fingerC2H2-type 4
TgeneZNF16chr8:145770633chr8:146157976ENST0000039490913321_34365683.0Zinc fingerC2H2-type 5
TgeneZNF16chr8:145770633chr8:146157976ENST0000039490913349_37165683.0Zinc fingerC2H2-type 6
TgeneZNF16chr8:145770633chr8:146157976ENST0000039490913377_39965683.0Zinc fingerC2H2-type 7
TgeneZNF16chr8:145770633chr8:146157976ENST0000039490913405_42765683.0Zinc fingerC2H2-type 8
TgeneZNF16chr8:145770633chr8:146157976ENST0000039490913433_45565683.0Zinc fingerC2H2-type 9
TgeneZNF16chr8:145770633chr8:146157976ENST0000039490913461_48365683.0Zinc fingerC2H2-type 10
TgeneZNF16chr8:145770633chr8:146157976ENST0000039490913489_51165683.0Zinc fingerC2H2-type 11
TgeneZNF16chr8:145770633chr8:146157976ENST0000039490913517_53965683.0Zinc fingerC2H2-type 12
TgeneZNF16chr8:145770633chr8:146157976ENST0000039490913545_56765683.0Zinc fingerC2H2-type 13
TgeneZNF16chr8:145770633chr8:146157976ENST0000039490913573_59565683.0Zinc fingerC2H2-type 14
TgeneZNF16chr8:145770633chr8:146157976ENST0000039490913601_62365683.0Zinc fingerC2H2-type 15
TgeneZNF16chr8:145770633chr8:146157976ENST0000039490913629_65165683.0Zinc fingerC2H2-type 16
TgeneZNF16chr8:145770633chr8:146157976ENST0000039490913657_67965683.0Zinc fingerC2H2-type 17

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneARHGAP39chr8:145770633chr8:146157976ENST00000276826-510722_8798401084.0DomainMyTH4
HgeneARHGAP39chr8:145770633chr8:146157976ENST00000276826-510890_10788401084.0DomainRho-GAP
HgeneARHGAP39chr8:145770633chr8:146157976ENST00000377307-511722_8798401115.0DomainMyTH4
HgeneARHGAP39chr8:145770633chr8:146157976ENST00000377307-511890_10788401115.0DomainRho-GAP
HgeneARHGAP39chr8:145770633chr8:146157976ENST00000540274-611722_8798401084.0DomainMyTH4
HgeneARHGAP39chr8:145770633chr8:146157976ENST00000540274-611890_10788401084.0DomainRho-GAP
TgeneZNF16chr8:145770633chr8:146157976ENST000002768162462_21065683.0RegionNote=Necessary for transcription activation
TgeneZNF16chr8:145770633chr8:146157976ENST000003949091362_21065683.0RegionNote=Necessary for transcription activation


Top

Fusion Gene Sequence for ARHGAP39-ZNF16


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>6105_6105_1_ARHGAP39-ZNF16_ARHGAP39_chr8_145770633_ENST00000540274_ZNF16_chr8_146157976_ENST00000276816_length(transcript)=4959nt_BP=2726nt
AGCACGGGCTGCCGCGGCAGCAGCGGCGGAGCAGCAGAGAGGCCGGGGAGCGGCGGCTGGCTCACGCGCGTCGCGCGGGCCGGGATGAGG
GACTGTGGCGGCGCGGCCCGCGCGCAGCCGGCCGTGCGGCACCTTCCCGTCTGATGCTGGCGTTGTGCGTATGGTGCCCTGACGTCTGTC
CACGTGGGCGCGGAAGCAAACAGCGATGTCCCAGACGCAGGACTACGAGTGCAGGAGCCATAATGTCGACCTGCCGGAGTCGAGGATTCC
AGGGTCGAACACTCGGTTGGAGTGGGTGGAGATCATCGAACCGCGCACCCGCGAGCGCATGTACGCCAACCTGGTCACCGGTGAGTGCGT
GTGGGACCCGCCGGCCGGCGTCCGCATCAAGCGCACCAGCGAGAACCAGTGGTGGGAGCTGTTCGACCCCAACACGTCCCGCTTCTACTA
CTACAATGCCAGCACGCAGCGCACGGTGTGGCACCGGCCGCAGGGCTGCGACATCATCCCGCTGGCCAAGCTGCAGACGCTGAAGCAGAA
CACGGAGTCCCCGCGCGCCTCGGCGGAGAGCAGCCCCGGGCGCGGCAGCAGCGTCAGCCGTGAGGGCAGCACCAGCTCCTCCCTGGAGCC
CGAGCCCGACACTGAGAAAGCGCAGGAGTTGCCAGCGAGGGCCGGGCGGCCCGCGGCGTTTGGGACAGTGAAGGAGGACAGCGGCAGCTC
TTCACCACCAGGAGTGTTCCTTGAGAAGGACTATGAGATTTACCGGGATTACAGTGCGGACGGCCAGCTTCTTCACTACAGGACCTCCTC
GCTGCGGTGGAACTCGGGCGCCAAAGAGCGCATGCTCATCAAGGTCGCTGATCGGGAGCCCAGCTTCCTCGCCGCCCAGGGCAATGGCTA
CGCCCCAGACGGCCCACCTGGGGTCCGCTCCCGCAGACCCTCCGGCAGCCAGCACTCACCCAGCCTGCAGACCTTCGCCCCGGAGGCTGA
CGGCACCATCTTCTTCCCAGAGAGGAGGCCGTCACCCTTCCTGAAGAGGGCCGAGCTCCCAGGGAGCAGCTCCCCGCTGCTGGCCCAGCC
CCGAAAGCCCTCCGGGGACTCGCAGCCCTCCTCCCCGCGCTATGGCTATGAACCCCCGCTCTACGAGGAGCCCCCAGTGGAGTACCAGGC
CCCCATCTACGATGAGCCCCCCATGGACGTGCAATTCGAGGCTGGCGGGGGCTACCAGGCCGGCTCTCCCCAGCGGTCGCCGGGCCGTAA
GCCCCGGCCGTTCCTCCAGCCCAACAAGCAGGGCCCCCCCTCGCCCTGCCAGCAGCTGGTGCTCACCAAGCAGAAGTGTCCCGAGCGCTT
CCTGAGCCTGGAGTACAGTCCCGCCGGCAAGGAGTACGTGCGGCAGCTGGTCTACGTGGAGCAGGCGGGCTCCAGCCCCAAGCTGCGCGC
CGGCCCGCGGCACAAGTACGCGCCCAACCCCGGCGGTGGTTCGTACTCCTTGCAGCCCAGCCCCTGCCTGCTGAGGGACCAGCGCCTGGG
CGTCAAGTCCGGAGACTACAGCACCATGGAGGGACCTGAGCTGCGGCACAGCCAGCCGCCCACGCCGCTGCCACAGGCCCAGGAGGATGC
CATGTCCTGGTCCAGCCAGCAGGACACCCTGTCCTCCACAGGCTACTCCCCGGGCACGCGCAAGCGGAAGAGCAGAAAGCCCTCTTTGTG
CCAAGCCACCAGCGCCACCCCCACTGAGGGCCCCGGGGACCTGCTTGTGGAGCAGCCCCTGGCCGAGGAACAGCCCCCGTGCGGGACCAG
CCTCGCCCCCGTGAAGCGAGCGGAAGGTGAGGCCGAAGGGGCGCGGGGCGCGGCCGAGCCCTTCCTGGCGCAGGCTCGGCTGGCCTGGGA
GGCGCAGCAGGCCCACTTCCACATGAAGCAGAGGAGCAGCTGGGACTCCCAGCAGGACGGCTCTGGCTACGAGAGCGACGGCGCCCTGCC
ACTGCCCATGCCCGGGCCGGTGGTGCGGGCCTTCAGCGAGGACGAGGCGCTGGCCCAGCAGGAGAACAGGCACTGGAGGAGGGGCACCTT
CGAGAAGCTAGGCTTCCCCCAGATCCTGCTGGAGAAGAGCGTCTCCGTGCAGACCAACCTGGCCTCACCAGAGCCCTACCTCCACCCCTC
ACAGTCTGAGGACCTCGCTGCCTGTGCCCAGTTCGAGAGCAGCCGGCAGAGCCGCAGCGGCGTTCCCAGCTCCAGCTGCGTCTTCCCCAC
TTTCACGCTGCGCAAGCCCTCCTCGGAGACGGACATCGAGAACTGGGCCTCCAAGCACTTCAACAAGCACACGCAGGGCCTCTTCCGGCG
GAAGGTGTCCATCGCCAACATGCTGGCCTGGAGCAGCGAGTCCATCAAGAAGCCCATGATCGTGACAAGCGACCGGCACGTGAAGAAGGA
GGCCTGCGAGCTCTTCAAGCTGATCCAGATGTACATGGGTGACCGGCGGGCCAAGGCCGACCCACTGCACGTGGCCCTGGAGGTGGCCAC
CAAGGGCTGGAGCGTGCAGGGCCTGCGGGACGAGCTCTACATCCAGCTGTGCCGGCAGACCACCGAGAACTTCCGCCTGGAGAGCCTGGC
CCGCGGCTGGGAGCTCATGGCCATCTGCCTGGCCTTTTTCCCGCCCACCCCCAAGTTCCACTCCTACCTGGAAGGCTACATCTACCGGCA
CATGGACCCCGTCAATGACACTAAAGATTGTGACACCAGGACTGAAGACAAGGAGTTTCTTCACAAGGAAGACATTCATGAAGATTTGGA
ATCACAGGCAGAAATATCAGAAAACTATGCTGGTGATGTTTCCCAGGTACCCGAGCTTGGAGATCTGTGTGATGATGTATCAGAAAGAGA
CTGGGGAGTCCCCGAAGGCAGGAGGCTGCCACAGTCCCTCTCCCAGGAGGGGGACTTCACACCAGCTGCCATGGGGCTCCTTAGGGGCCC
CTTAGGGGAGAAAGATCTGGACTGTAATGGTTTTGACAGTCGCTTCAGTCTGAGCCCAAACCTGATGGCATGTCAGGAAATCCCTACAGA
AGAGAGGCCACATCCATATGACATGGGTGGCCAGAGTTTCCAGCACAGTGTGGACCTAACTGGTCATGAGGGGGTTCCCACAGCTGAAAG
TCCACTCATATGTAATGAGTGTGGGAAAACCTTCCAAGGAAATCCTGACCTTATTCAGCGTCAAATAGTCCACACTGGGGAGGCTTCCTT
TATGTGTGATGATTGTGGGAAAACCTTCAGCCAGAACTCAGTTCTTAAAAACCGTCATCGATCTCATATGAGTGAGAAAGCTTACCAGTG
CAGCGAATGTGGGAAAGCCTTCCGAGGGCACTCAGACTTTTCTAGGCATCAGAGTCACCACAGCAGTGAGAGGCCTTATATGTGTAATGA
ATGTGGAAAAGCCTTCAGCCAGAACTCGAGCCTTAAAAAGCACCAAAAGTCTCACATGAGTGAGAAGCCCTATGAATGCAATGAATGTGG
GAAGGCTTTTAGGCGGAGCTCAAACCTCATCCAACATCAAAGAATCCATTCTGGGGAGAAACCGTATGTGTGCAGTGAGTGTGGGAAGGC
CTTCAGGCGAAGCTCAAACCTCATCAAACACCACAGGACTCACACAGGAGAGAAGCCTTTTGAGTGTGGCGAGTGTGGGAAAGCCTTCAG
CCAGAGTGCACACCTGAGGAAGCACCAGAGGGTCCACACTGGAGAGAAGCCTTATGAGTGTAATGATTGTGGCAAGCCCTTCAGTCGGGT
CTCCAACCTCATTAAGCACCACAGGGTTCACACTGGAGAGAAGCCCTATAAGTGCAGTGACTGTGGGAAAGCATTTAGTCAGAGCTCCAG
CCTTATTCAGCATCGGAGAATTCACACTGGAGAAAAGCCTCACGTGTGTAATGTATGTGGAAAAGCCTTTAGTTATAGCTCAGTGCTCCG
AAAGCACCAGATCATCCACACGGGAGAGAAGCCGTACAGATGCAGTGTCTGTGGGAAGGCCTTCAGCCACAGCTCAGCCCTCATTCAGCA
CCAGGGCGTGCACACAGGCGACAAGCCCTACGCCTGCCACGAGTGTGGGAAGACCTTTGGTCGCAGCTCCAACCTCATCCTTCACCAGCG
AGTCCACACTGGAGAGAAGCCCTATGAATGTACTGAATGTGGAAAAACCTTCAGCCAGAGCTCAACCCTCATTCAGCATCAGAGGATTCA
TAATGGGCTGAAGCCCCATGAATGTAACCAGTGTGGTAAAGCCTTCAACCGAAGCTCAAATCTCATTCACCACCAGAAAGTTCATACTGG
GGAAAAACCCTACACCTGTGTTGAATGTGGTAAGGGCTTCAGCCAGAGCTCACACCTCATTCAGCATCAGATAATCCACACGGGCGAGCG
CCCCTACAAATGCAGTGAGTGTGGGAAAGCCTTCAGTCAGCGTTCGGTCCTCATCCAGCACCAGAGGATTCACACTGGGGTGAAGCCCTA
TGACTGTGCTGCTTGTGGGAAAGCCTTCAGCCAGCGATCAAAGTTGATCAAACACCAGTTGATTCACACCAGGGAATAGGCTGTTGGGCT
GGCAGGAGTGAAACCGAGCATAGTTTCCTCTCCAACTCCTCTTTGGCCATTGTCTCAGCCTCTGCCACTTCCCAGACCGAAAGCCTGGAC
TCAGCTCACTGCCTACATCCAGTGGCCACATAGCCTGGGACCCTCCTTTGAAACATCCTTTACAGGCTCCCTTCTCACTGCCACTGCTCT
TGCCTCTTGTGATGTCTTGGGTTTGGGCTTGTTTTTACAGCTTGTGAACGGACTGCACGTTTGTTACAAGGGAGAAGATTATGGAGGCTG
CATATTCATGAATAGAGTTTATTATTATAATGAAAAGTTACCAAAAAAGTAAAGTGACGTTTGGTTTGAGATAACCATAGTAGTTTGTTT
GATTGGTAA

>6105_6105_1_ARHGAP39-ZNF16_ARHGAP39_chr8_145770633_ENST00000540274_ZNF16_chr8_146157976_ENST00000276816_length(amino acids)=1467AA_BP=1067
MSTWARKQTAMSQTQDYECRSHNVDLPESRIPGSNTRLEWVEIIEPRTRERMYANLVTGECVWDPPAGVRIKRTSENQWWELFDPNTSRF
YYYNASTQRTVWHRPQGCDIIPLAKLQTLKQNTESPRASAESSPGRGSSVSREGSTSSSLEPEPDTEKAQELPARAGRPAAFGTVKEDSG
SSSPPGVFLEKDYEIYRDYSADGQLLHYRTSSLRWNSGAKERMLIKVADREPSFLAAQGNGYAPDGPPGVRSRRPSGSQHSPSLQTFAPE
ADGTIFFPERRPSPFLKRAELPGSSSPLLAQPRKPSGDSQPSSPRYGYEPPLYEEPPVEYQAPIYDEPPMDVQFEAGGGYQAGSPQRSPG
RKPRPFLQPNKQGPPSPCQQLVLTKQKCPERFLSLEYSPAGKEYVRQLVYVEQAGSSPKLRAGPRHKYAPNPGGGSYSLQPSPCLLRDQR
LGVKSGDYSTMEGPELRHSQPPTPLPQAQEDAMSWSSQQDTLSSTGYSPGTRKRKSRKPSLCQATSATPTEGPGDLLVEQPLAEEQPPCG
TSLAPVKRAEGEAEGARGAAEPFLAQARLAWEAQQAHFHMKQRSSWDSQQDGSGYESDGALPLPMPGPVVRAFSEDEALAQQENRHWRRG
TFEKLGFPQILLEKSVSVQTNLASPEPYLHPSQSEDLAACAQFESSRQSRSGVPSSSCVFPTFTLRKPSSETDIENWASKHFNKHTQGLF
RRKVSIANMLAWSSESIKKPMIVTSDRHVKKEACELFKLIQMYMGDRRAKADPLHVALEVATKGWSVQGLRDELYIQLCRQTTENFRLES
LARGWELMAICLAFFPPTPKFHSYLEGYIYRHMDPVNDTKDCDTRTEDKEFLHKEDIHEDLESQAEISENYAGDVSQVPELGDLCDDVSE
RDWGVPEGRRLPQSLSQEGDFTPAAMGLLRGPLGEKDLDCNGFDSRFSLSPNLMACQEIPTEERPHPYDMGGQSFQHSVDLTGHEGVPTA
ESPLICNECGKTFQGNPDLIQRQIVHTGEASFMCDDCGKTFSQNSVLKNRHRSHMSEKAYQCSECGKAFRGHSDFSRHQSHHSSERPYMC
NECGKAFSQNSSLKKHQKSHMSEKPYECNECGKAFRRSSNLIQHQRIHSGEKPYVCSECGKAFRRSSNLIKHHRTHTGEKPFECGECGKA
FSQSAHLRKHQRVHTGEKPYECNDCGKPFSRVSNLIKHHRVHTGEKPYKCSDCGKAFSQSSSLIQHRRIHTGEKPHVCNVCGKAFSYSSV
LRKHQIIHTGEKPYRCSVCGKAFSHSSALIQHQGVHTGDKPYACHECGKTFGRSSNLILHQRVHTGEKPYECTECGKTFSQSSTLIQHQR
IHNGLKPHECNQCGKAFNRSSNLIHHQKVHTGEKPYTCVECGKGFSQSSHLIQHQIIHTGERPYKCSECGKAFSQRSVLIQHQRIHTGVK
PYDCAACGKAFSQRSKLIKHQLIHTRE

--------------------------------------------------------------
>6105_6105_2_ARHGAP39-ZNF16_ARHGAP39_chr8_145770633_ENST00000540274_ZNF16_chr8_146157976_ENST00000394909_length(transcript)=4932nt_BP=2726nt
AGCACGGGCTGCCGCGGCAGCAGCGGCGGAGCAGCAGAGAGGCCGGGGAGCGGCGGCTGGCTCACGCGCGTCGCGCGGGCCGGGATGAGG
GACTGTGGCGGCGCGGCCCGCGCGCAGCCGGCCGTGCGGCACCTTCCCGTCTGATGCTGGCGTTGTGCGTATGGTGCCCTGACGTCTGTC
CACGTGGGCGCGGAAGCAAACAGCGATGTCCCAGACGCAGGACTACGAGTGCAGGAGCCATAATGTCGACCTGCCGGAGTCGAGGATTCC
AGGGTCGAACACTCGGTTGGAGTGGGTGGAGATCATCGAACCGCGCACCCGCGAGCGCATGTACGCCAACCTGGTCACCGGTGAGTGCGT
GTGGGACCCGCCGGCCGGCGTCCGCATCAAGCGCACCAGCGAGAACCAGTGGTGGGAGCTGTTCGACCCCAACACGTCCCGCTTCTACTA
CTACAATGCCAGCACGCAGCGCACGGTGTGGCACCGGCCGCAGGGCTGCGACATCATCCCGCTGGCCAAGCTGCAGACGCTGAAGCAGAA
CACGGAGTCCCCGCGCGCCTCGGCGGAGAGCAGCCCCGGGCGCGGCAGCAGCGTCAGCCGTGAGGGCAGCACCAGCTCCTCCCTGGAGCC
CGAGCCCGACACTGAGAAAGCGCAGGAGTTGCCAGCGAGGGCCGGGCGGCCCGCGGCGTTTGGGACAGTGAAGGAGGACAGCGGCAGCTC
TTCACCACCAGGAGTGTTCCTTGAGAAGGACTATGAGATTTACCGGGATTACAGTGCGGACGGCCAGCTTCTTCACTACAGGACCTCCTC
GCTGCGGTGGAACTCGGGCGCCAAAGAGCGCATGCTCATCAAGGTCGCTGATCGGGAGCCCAGCTTCCTCGCCGCCCAGGGCAATGGCTA
CGCCCCAGACGGCCCACCTGGGGTCCGCTCCCGCAGACCCTCCGGCAGCCAGCACTCACCCAGCCTGCAGACCTTCGCCCCGGAGGCTGA
CGGCACCATCTTCTTCCCAGAGAGGAGGCCGTCACCCTTCCTGAAGAGGGCCGAGCTCCCAGGGAGCAGCTCCCCGCTGCTGGCCCAGCC
CCGAAAGCCCTCCGGGGACTCGCAGCCCTCCTCCCCGCGCTATGGCTATGAACCCCCGCTCTACGAGGAGCCCCCAGTGGAGTACCAGGC
CCCCATCTACGATGAGCCCCCCATGGACGTGCAATTCGAGGCTGGCGGGGGCTACCAGGCCGGCTCTCCCCAGCGGTCGCCGGGCCGTAA
GCCCCGGCCGTTCCTCCAGCCCAACAAGCAGGGCCCCCCCTCGCCCTGCCAGCAGCTGGTGCTCACCAAGCAGAAGTGTCCCGAGCGCTT
CCTGAGCCTGGAGTACAGTCCCGCCGGCAAGGAGTACGTGCGGCAGCTGGTCTACGTGGAGCAGGCGGGCTCCAGCCCCAAGCTGCGCGC
CGGCCCGCGGCACAAGTACGCGCCCAACCCCGGCGGTGGTTCGTACTCCTTGCAGCCCAGCCCCTGCCTGCTGAGGGACCAGCGCCTGGG
CGTCAAGTCCGGAGACTACAGCACCATGGAGGGACCTGAGCTGCGGCACAGCCAGCCGCCCACGCCGCTGCCACAGGCCCAGGAGGATGC
CATGTCCTGGTCCAGCCAGCAGGACACCCTGTCCTCCACAGGCTACTCCCCGGGCACGCGCAAGCGGAAGAGCAGAAAGCCCTCTTTGTG
CCAAGCCACCAGCGCCACCCCCACTGAGGGCCCCGGGGACCTGCTTGTGGAGCAGCCCCTGGCCGAGGAACAGCCCCCGTGCGGGACCAG
CCTCGCCCCCGTGAAGCGAGCGGAAGGTGAGGCCGAAGGGGCGCGGGGCGCGGCCGAGCCCTTCCTGGCGCAGGCTCGGCTGGCCTGGGA
GGCGCAGCAGGCCCACTTCCACATGAAGCAGAGGAGCAGCTGGGACTCCCAGCAGGACGGCTCTGGCTACGAGAGCGACGGCGCCCTGCC
ACTGCCCATGCCCGGGCCGGTGGTGCGGGCCTTCAGCGAGGACGAGGCGCTGGCCCAGCAGGAGAACAGGCACTGGAGGAGGGGCACCTT
CGAGAAGCTAGGCTTCCCCCAGATCCTGCTGGAGAAGAGCGTCTCCGTGCAGACCAACCTGGCCTCACCAGAGCCCTACCTCCACCCCTC
ACAGTCTGAGGACCTCGCTGCCTGTGCCCAGTTCGAGAGCAGCCGGCAGAGCCGCAGCGGCGTTCCCAGCTCCAGCTGCGTCTTCCCCAC
TTTCACGCTGCGCAAGCCCTCCTCGGAGACGGACATCGAGAACTGGGCCTCCAAGCACTTCAACAAGCACACGCAGGGCCTCTTCCGGCG
GAAGGTGTCCATCGCCAACATGCTGGCCTGGAGCAGCGAGTCCATCAAGAAGCCCATGATCGTGACAAGCGACCGGCACGTGAAGAAGGA
GGCCTGCGAGCTCTTCAAGCTGATCCAGATGTACATGGGTGACCGGCGGGCCAAGGCCGACCCACTGCACGTGGCCCTGGAGGTGGCCAC
CAAGGGCTGGAGCGTGCAGGGCCTGCGGGACGAGCTCTACATCCAGCTGTGCCGGCAGACCACCGAGAACTTCCGCCTGGAGAGCCTGGC
CCGCGGCTGGGAGCTCATGGCCATCTGCCTGGCCTTTTTCCCGCCCACCCCCAAGTTCCACTCCTACCTGGAAGGCTACATCTACCGGCA
CATGGACCCCGTCAATGACACTAAAGATTGTGACACCAGGACTGAAGACAAGGAGTTTCTTCACAAGGAAGACATTCATGAAGATTTGGA
ATCACAGGCAGAAATATCAGAAAACTATGCTGGTGATGTTTCCCAGGTACCCGAGCTTGGAGATCTGTGTGATGATGTATCAGAAAGAGA
CTGGGGAGTCCCCGAAGGCAGGAGGCTGCCACAGTCCCTCTCCCAGGAGGGGGACTTCACACCAGCTGCCATGGGGCTCCTTAGGGGCCC
CTTAGGGGAGAAAGATCTGGACTGTAATGGTTTTGACAGTCGCTTCAGTCTGAGCCCAAACCTGATGGCATGTCAGGAAATCCCTACAGA
AGAGAGGCCACATCCATATGACATGGGTGGCCAGAGTTTCCAGCACAGTGTGGACCTAACTGGTCATGAGGGGGTTCCCACAGCTGAAAG
TCCACTCATATGTAATGAGTGTGGGAAAACCTTCCAAGGAAATCCTGACCTTATTCAGCGTCAAATAGTCCACACTGGGGAGGCTTCCTT
TATGTGTGATGATTGTGGGAAAACCTTCAGCCAGAACTCAGTTCTTAAAAACCGTCATCGATCTCATATGAGTGAGAAAGCTTACCAGTG
CAGCGAATGTGGGAAAGCCTTCCGAGGGCACTCAGACTTTTCTAGGCATCAGAGTCACCACAGCAGTGAGAGGCCTTATATGTGTAATGA
ATGTGGAAAAGCCTTCAGCCAGAACTCGAGCCTTAAAAAGCACCAAAAGTCTCACATGAGTGAGAAGCCCTATGAATGCAATGAATGTGG
GAAGGCTTTTAGGCGGAGCTCAAACCTCATCCAACATCAAAGAATCCATTCTGGGGAGAAACCGTATGTGTGCAGTGAGTGTGGGAAGGC
CTTCAGGCGAAGCTCAAACCTCATCAAACACCACAGGACTCACACAGGAGAGAAGCCTTTTGAGTGTGGCGAGTGTGGGAAAGCCTTCAG
CCAGAGTGCACACCTGAGGAAGCACCAGAGGGTCCACACTGGAGAGAAGCCTTATGAGTGTAATGATTGTGGCAAGCCCTTCAGTCGGGT
CTCCAACCTCATTAAGCACCACAGGGTTCACACTGGAGAGAAGCCCTATAAGTGCAGTGACTGTGGGAAAGCATTTAGTCAGAGCTCCAG
CCTTATTCAGCATCGGAGAATTCACACTGGAGAAAAGCCTCACGTGTGTAATGTATGTGGAAAAGCCTTTAGTTATAGCTCAGTGCTCCG
AAAGCACCAGATCATCCACACGGGAGAGAAGCCGTACAGATGCAGTGTCTGTGGGAAGGCCTTCAGCCACAGCTCAGCCCTCATTCAGCA
CCAGGGCGTGCACACAGGCGACAAGCCCTACGCCTGCCACGAGTGTGGGAAGACCTTTGGTCGCAGCTCCAACCTCATCCTTCACCAGCG
AGTCCACACTGGAGAGAAGCCCTATGAATGTACTGAATGTGGAAAAACCTTCAGCCAGAGCTCAACCCTCATTCAGCATCAGAGGATTCA
TAATGGGCTGAAGCCCCATGAATGTAACCAGTGTGGTAAAGCCTTCAACCGAAGCTCAAATCTCATTCACCACCAGAAAGTTCATACTGG
GGAAAAACCCTACACCTGTGTTGAATGTGGTAAGGGCTTCAGCCAGAGCTCACACCTCATTCAGCATCAGATAATCCACACGGGCGAGCG
CCCCTACAAATGCAGTGAGTGTGGGAAAGCCTTCAGTCAGCGTTCGGTCCTCATCCAGCACCAGAGGATTCACACTGGGGTGAAGCCCTA
TGACTGTGCTGCTTGTGGGAAAGCCTTCAGCCAGCGATCAAAGTTGATCAAACACCAGTTGATTCACACCAGGGAATAGGCTGTTGGGCT
GGCAGGAGTGAAACCGAGCATAGTTTCCTCTCCAACTCCTCTTTGGCCATTGTCTCAGCCTCTGCCACTTCCCAGACCGAAAGCCTGGAC
TCAGCTCACTGCCTACATCCAGTGGCCACATAGCCTGGGACCCTCCTTTGAAACATCCTTTACAGGCTCCCTTCTCACTGCCACTGCTCT
TGCCTCTTGTGATGTCTTGGGTTTGGGCTTGTTTTTACAGCTTGTGAACGGACTGCACGTTTGTTACAAGGGAGAAGATTATGGAGGCTG
CATATTCATGAATAGAGTTTATTATTATAATGAAAAGTTACCAAAAAAGTAAAGTGACGTTTGGTTTGAGAT

>6105_6105_2_ARHGAP39-ZNF16_ARHGAP39_chr8_145770633_ENST00000540274_ZNF16_chr8_146157976_ENST00000394909_length(amino acids)=1467AA_BP=1067
MSTWARKQTAMSQTQDYECRSHNVDLPESRIPGSNTRLEWVEIIEPRTRERMYANLVTGECVWDPPAGVRIKRTSENQWWELFDPNTSRF
YYYNASTQRTVWHRPQGCDIIPLAKLQTLKQNTESPRASAESSPGRGSSVSREGSTSSSLEPEPDTEKAQELPARAGRPAAFGTVKEDSG
SSSPPGVFLEKDYEIYRDYSADGQLLHYRTSSLRWNSGAKERMLIKVADREPSFLAAQGNGYAPDGPPGVRSRRPSGSQHSPSLQTFAPE
ADGTIFFPERRPSPFLKRAELPGSSSPLLAQPRKPSGDSQPSSPRYGYEPPLYEEPPVEYQAPIYDEPPMDVQFEAGGGYQAGSPQRSPG
RKPRPFLQPNKQGPPSPCQQLVLTKQKCPERFLSLEYSPAGKEYVRQLVYVEQAGSSPKLRAGPRHKYAPNPGGGSYSLQPSPCLLRDQR
LGVKSGDYSTMEGPELRHSQPPTPLPQAQEDAMSWSSQQDTLSSTGYSPGTRKRKSRKPSLCQATSATPTEGPGDLLVEQPLAEEQPPCG
TSLAPVKRAEGEAEGARGAAEPFLAQARLAWEAQQAHFHMKQRSSWDSQQDGSGYESDGALPLPMPGPVVRAFSEDEALAQQENRHWRRG
TFEKLGFPQILLEKSVSVQTNLASPEPYLHPSQSEDLAACAQFESSRQSRSGVPSSSCVFPTFTLRKPSSETDIENWASKHFNKHTQGLF
RRKVSIANMLAWSSESIKKPMIVTSDRHVKKEACELFKLIQMYMGDRRAKADPLHVALEVATKGWSVQGLRDELYIQLCRQTTENFRLES
LARGWELMAICLAFFPPTPKFHSYLEGYIYRHMDPVNDTKDCDTRTEDKEFLHKEDIHEDLESQAEISENYAGDVSQVPELGDLCDDVSE
RDWGVPEGRRLPQSLSQEGDFTPAAMGLLRGPLGEKDLDCNGFDSRFSLSPNLMACQEIPTEERPHPYDMGGQSFQHSVDLTGHEGVPTA
ESPLICNECGKTFQGNPDLIQRQIVHTGEASFMCDDCGKTFSQNSVLKNRHRSHMSEKAYQCSECGKAFRGHSDFSRHQSHHSSERPYMC
NECGKAFSQNSSLKKHQKSHMSEKPYECNECGKAFRRSSNLIQHQRIHSGEKPYVCSECGKAFRRSSNLIKHHRTHTGEKPFECGECGKA
FSQSAHLRKHQRVHTGEKPYECNDCGKPFSRVSNLIKHHRVHTGEKPYKCSDCGKAFSQSSSLIQHRRIHTGEKPHVCNVCGKAFSYSSV
LRKHQIIHTGEKPYRCSVCGKAFSHSSALIQHQGVHTGDKPYACHECGKTFGRSSNLILHQRVHTGEKPYECTECGKTFSQSSTLIQHQR
IHNGLKPHECNQCGKAFNRSSNLIHHQKVHTGEKPYTCVECGKGFSQSSHLIQHQIIHTGERPYKCSECGKAFSQRSVLIQHQRIHTGVK
PYDCAACGKAFSQRSKLIKHQLIHTRE

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for ARHGAP39-ZNF16


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for ARHGAP39-ZNF16


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for ARHGAP39-ZNF16


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource