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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:ANP32E-ACIN1 (FusionGDB2 ID:HG81611TG22985) |
Fusion Gene Summary for ANP32E-ACIN1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: ANP32E-ACIN1 | Fusion gene ID: hg81611tg22985 | Hgene | Tgene | Gene symbol | ANP32E | ACIN1 | Gene ID | 81611 | 22985 |
| Gene name | acidic nuclear phosphoprotein 32 family member E | apoptotic chromatin condensation inducer 1 | |
| Synonyms | LANP-L|LANPL | ACINUS|ACN|fSAP152 | |
| Cytomap | ('ANP32E')('ACIN1') 1q21.2 | 14q11.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | acidic leucine-rich nuclear phosphoprotein 32 family member ELANP-like proteinacidic (leucine-rich) nuclear phosphoprotein 32 family, member Eleucine-rich acidic nuclear protein like | apoptotic chromatin condensation inducer in the nucleusfunctional spliceosome-associated protein 152 | |
| Modification date | 20200313 | 20200313 | |
| UniProtAcc | Q9BTT0 | Q9UKV3 | |
| Ensembl transtripts involved in fusion gene | ENST00000314136, ENST00000369114, ENST00000369115, ENST00000369116, ENST00000369119, ENST00000436748, ENST00000533654, | ||
| Fusion gene scores | * DoF score | 5 X 5 X 3=75 | 11 X 11 X 4=484 |
| # samples | 5 | 12 | |
| ** MAII score | log2(5/75*10)=-0.584962500721156 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(12/484*10)=-2.01197264166608 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: ANP32E [Title/Abstract] AND ACIN1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | ANP32E(150195513)-ACIN1(23532752), # samples:1 | ||
| Anticipated loss of major functional domain due to fusion event. | ANP32E-ACIN1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. ANP32E-ACIN1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. ANP32E-ACIN1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. ANP32E-ACIN1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. ANP32E-ACIN1 seems lost the major protein functional domain in Hgene partner, which is a epigenetic factor due to the frame-shifted ORF. ANP32E-ACIN1 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF. ANP32E-ACIN1 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | ANP32E | GO:0043486 | histone exchange | 24463511 |
| Tgene | ACIN1 | GO:0030263 | apoptotic chromosome condensation | 10490026 |
| Fusion gene breakpoints across ANP32E (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across ACIN1 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
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Fusion Gene ORF analysis for ANP32E-ACIN1 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000369119 | ENST00000557515 | ANP32E | chr1 | 150195513 | - | ACIN1 | chr14 | 23532752 | - | 0.000489665 | 0.9995103 |
| ENST00000369119 | ENST00000338631 | ANP32E | chr1 | 150195513 | - | ACIN1 | chr14 | 23532752 | - | 0.000463639 | 0.9995364 |
| ENST00000369119 | ENST00000357481 | ANP32E | chr1 | 150195513 | - | ACIN1 | chr14 | 23532752 | - | 0.000463639 | 0.9995364 |
| ENST00000369119 | ENST00000605057 | ANP32E | chr1 | 150195513 | - | ACIN1 | chr14 | 23532752 | - | 0.000463639 | 0.9995364 |
| ENST00000369119 | ENST00000457657 | ANP32E | chr1 | 150195513 | - | ACIN1 | chr14 | 23532752 | - | 0.000463639 | 0.9995364 |
| ENST00000369119 | ENST00000262710 | ANP32E | chr1 | 150195513 | - | ACIN1 | chr14 | 23532752 | - | 0.000463639 | 0.9995364 |
| ENST00000369119 | ENST00000397341 | ANP32E | chr1 | 150195513 | - | ACIN1 | chr14 | 23532752 | - | 0.000468652 | 0.9995314 |
| ENST00000369119 | ENST00000555053 | ANP32E | chr1 | 150195513 | - | ACIN1 | chr14 | 23532752 | - | 0.000573929 | 0.9994261 |
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Fusion Genomic Features for ANP32E-ACIN1 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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Fusion Protein Features for ANP32E-ACIN1 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr1:150195513/chr14:23532752) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| ANP32E | ACIN1 |
| FUNCTION: Histone chaperone that specifically mediates the genome-wide removal of histone H2A.Z/H2AZ1 from the nucleosome: removes H2A.Z/H2AZ1 from its normal sites of deposition, especially from enhancer and insulator regions. Not involved in deposition of H2A.Z/H2AZ1 in the nucleosome. May stabilize the evicted H2A.Z/H2AZ1-H2B dimer, thus shifting the equilibrium towards dissociation and the off-chromatin state (PubMed:24463511). Inhibits activity of protein phosphatase 2A (PP2A). Does not inhibit protein phosphatase 1. May play a role in cerebellar development and synaptogenesis. {ECO:0000269|PubMed:24463511}. | FUNCTION: Auxiliary component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Component of the ASAP complexes which bind RNA in a sequence-independent manner and are proposed to be recruited to the EJC prior to or during the splicing process and to regulate specific excision of introns in specific transcription subsets; ACIN1 confers RNA-binding to the complex. The ASAP complex can inhibit RNA processing during in vitro splicing reactions. The ASAP complex promotes apoptosis and is disassembled after induction of apoptosis. Involved in the splicing modulation of BCL2L1/Bcl-X (and probably other apoptotic genes); specifically inhibits formation of proapoptotic isoforms such as Bcl-X(S); the activity is different from the established EJC assembly and function. Induces apoptotic chromatin condensation after activation by CASP3. Regulates cyclin A1, but not cyclin A2, expression in leukemia cells. {ECO:0000269|PubMed:10490026, ECO:0000269|PubMed:12665594, ECO:0000269|PubMed:18559500, ECO:0000269|PubMed:22203037, ECO:0000269|PubMed:22388736}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | ANP32E | chr1:150195513 | chr14:23532752 | ENST00000314136 | - | 6 | 7 | 123_161 | 245 | 269.0 | Domain | Note=LRRCT |
| Hgene | ANP32E | chr1:150195513 | chr14:23532752 | ENST00000369119 | - | 6 | 7 | 123_161 | 197 | 221.0 | Domain | Note=LRRCT |
| Hgene | ANP32E | chr1:150195513 | chr14:23532752 | ENST00000436748 | - | 5 | 6 | 123_161 | 204 | 228.0 | Domain | Note=LRRCT |
| Hgene | ANP32E | chr1:150195513 | chr14:23532752 | ENST00000314136 | - | 6 | 7 | 18_38 | 245 | 269.0 | Repeat | Note=LRR 1 |
| Hgene | ANP32E | chr1:150195513 | chr14:23532752 | ENST00000314136 | - | 6 | 7 | 43_64 | 245 | 269.0 | Repeat | Note=LRR 2 |
| Hgene | ANP32E | chr1:150195513 | chr14:23532752 | ENST00000314136 | - | 6 | 7 | 65_87 | 245 | 269.0 | Repeat | Note=LRR 3 |
| Hgene | ANP32E | chr1:150195513 | chr14:23532752 | ENST00000314136 | - | 6 | 7 | 89_110 | 245 | 269.0 | Repeat | Note=LRR 4 |
| Hgene | ANP32E | chr1:150195513 | chr14:23532752 | ENST00000369119 | - | 6 | 7 | 18_38 | 197 | 221.0 | Repeat | Note=LRR 1 |
| Hgene | ANP32E | chr1:150195513 | chr14:23532752 | ENST00000369119 | - | 6 | 7 | 43_64 | 197 | 221.0 | Repeat | Note=LRR 2 |
| Hgene | ANP32E | chr1:150195513 | chr14:23532752 | ENST00000369119 | - | 6 | 7 | 65_87 | 197 | 221.0 | Repeat | Note=LRR 3 |
| Hgene | ANP32E | chr1:150195513 | chr14:23532752 | ENST00000369119 | - | 6 | 7 | 89_110 | 197 | 221.0 | Repeat | Note=LRR 4 |
| Hgene | ANP32E | chr1:150195513 | chr14:23532752 | ENST00000436748 | - | 5 | 6 | 18_38 | 204 | 228.0 | Repeat | Note=LRR 1 |
| Hgene | ANP32E | chr1:150195513 | chr14:23532752 | ENST00000436748 | - | 5 | 6 | 43_64 | 204 | 228.0 | Repeat | Note=LRR 2 |
| Hgene | ANP32E | chr1:150195513 | chr14:23532752 | ENST00000436748 | - | 5 | 6 | 65_87 | 204 | 228.0 | Repeat | Note=LRR 3 |
| Hgene | ANP32E | chr1:150195513 | chr14:23532752 | ENST00000436748 | - | 5 | 6 | 89_110 | 204 | 228.0 | Repeat | Note=LRR 4 |
| Tgene | ACIN1 | chr1:150195513 | chr14:23532752 | ENST00000262710 | 0 | 19 | 1114_1131 | 0 | 1342.0 | Compositional bias | Note=Pro-rich | |
| Tgene | ACIN1 | chr1:150195513 | chr14:23532752 | ENST00000262710 | 0 | 19 | 1132_1341 | 0 | 1342.0 | Compositional bias | Note=Arg/Asp/Glu/Lys-rich | |
| Tgene | ACIN1 | chr1:150195513 | chr14:23532752 | ENST00000262710 | 0 | 19 | 142_442 | 0 | 1342.0 | Compositional bias | Note=Glu-rich | |
| Tgene | ACIN1 | chr1:150195513 | chr14:23532752 | ENST00000262710 | 0 | 19 | 573_676 | 0 | 1342.0 | Compositional bias | Note=Ser-rich | |
| Tgene | ACIN1 | chr1:150195513 | chr14:23532752 | ENST00000338631 | 0 | 12 | 1114_1131 | 0 | 615.0 | Compositional bias | Note=Pro-rich | |
| Tgene | ACIN1 | chr1:150195513 | chr14:23532752 | ENST00000338631 | 0 | 12 | 1132_1341 | 0 | 615.0 | Compositional bias | Note=Arg/Asp/Glu/Lys-rich | |
| Tgene | ACIN1 | chr1:150195513 | chr14:23532752 | ENST00000338631 | 0 | 12 | 142_442 | 0 | 615.0 | Compositional bias | Note=Glu-rich | |
| Tgene | ACIN1 | chr1:150195513 | chr14:23532752 | ENST00000338631 | 0 | 12 | 573_676 | 0 | 615.0 | Compositional bias | Note=Ser-rich | |
| Tgene | ACIN1 | chr1:150195513 | chr14:23532752 | ENST00000357481 | 0 | 13 | 1114_1131 | 0 | 584.0 | Compositional bias | Note=Pro-rich | |
| Tgene | ACIN1 | chr1:150195513 | chr14:23532752 | ENST00000357481 | 0 | 13 | 1132_1341 | 0 | 584.0 | Compositional bias | Note=Arg/Asp/Glu/Lys-rich | |
| Tgene | ACIN1 | chr1:150195513 | chr14:23532752 | ENST00000357481 | 0 | 13 | 142_442 | 0 | 584.0 | Compositional bias | Note=Glu-rich | |
| Tgene | ACIN1 | chr1:150195513 | chr14:23532752 | ENST00000357481 | 0 | 13 | 573_676 | 0 | 584.0 | Compositional bias | Note=Ser-rich | |
| Tgene | ACIN1 | chr1:150195513 | chr14:23532752 | ENST00000397341 | 0 | 12 | 1114_1131 | 0 | 584.0 | Compositional bias | Note=Pro-rich | |
| Tgene | ACIN1 | chr1:150195513 | chr14:23532752 | ENST00000397341 | 0 | 12 | 1132_1341 | 0 | 584.0 | Compositional bias | Note=Arg/Asp/Glu/Lys-rich | |
| Tgene | ACIN1 | chr1:150195513 | chr14:23532752 | ENST00000397341 | 0 | 12 | 142_442 | 0 | 584.0 | Compositional bias | Note=Glu-rich | |
| Tgene | ACIN1 | chr1:150195513 | chr14:23532752 | ENST00000397341 | 0 | 12 | 573_676 | 0 | 584.0 | Compositional bias | Note=Ser-rich | |
| Tgene | ACIN1 | chr1:150195513 | chr14:23532752 | ENST00000555053 | 0 | 19 | 1114_1131 | 0 | 1329.0 | Compositional bias | Note=Pro-rich | |
| Tgene | ACIN1 | chr1:150195513 | chr14:23532752 | ENST00000555053 | 0 | 19 | 1132_1341 | 0 | 1329.0 | Compositional bias | Note=Arg/Asp/Glu/Lys-rich | |
| Tgene | ACIN1 | chr1:150195513 | chr14:23532752 | ENST00000555053 | 0 | 19 | 142_442 | 0 | 1329.0 | Compositional bias | Note=Glu-rich | |
| Tgene | ACIN1 | chr1:150195513 | chr14:23532752 | ENST00000555053 | 0 | 19 | 573_676 | 0 | 1329.0 | Compositional bias | Note=Ser-rich | |
| Tgene | ACIN1 | chr1:150195513 | chr14:23532752 | ENST00000262710 | 0 | 19 | 72_106 | 0 | 1342.0 | Domain | SAP | |
| Tgene | ACIN1 | chr1:150195513 | chr14:23532752 | ENST00000338631 | 0 | 12 | 72_106 | 0 | 615.0 | Domain | SAP | |
| Tgene | ACIN1 | chr1:150195513 | chr14:23532752 | ENST00000357481 | 0 | 13 | 72_106 | 0 | 584.0 | Domain | SAP | |
| Tgene | ACIN1 | chr1:150195513 | chr14:23532752 | ENST00000397341 | 0 | 12 | 72_106 | 0 | 584.0 | Domain | SAP | |
| Tgene | ACIN1 | chr1:150195513 | chr14:23532752 | ENST00000555053 | 0 | 19 | 72_106 | 0 | 1329.0 | Domain | SAP |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | ANP32E | chr1:150195513 | chr14:23532752 | ENST00000314136 | - | 6 | 7 | 151_266 | 245 | 269.0 | Compositional bias | Note=Asp/Glu-rich (highly acidic) |
| Hgene | ANP32E | chr1:150195513 | chr14:23532752 | ENST00000369119 | - | 6 | 7 | 151_266 | 197 | 221.0 | Compositional bias | Note=Asp/Glu-rich (highly acidic) |
| Hgene | ANP32E | chr1:150195513 | chr14:23532752 | ENST00000436748 | - | 5 | 6 | 151_266 | 204 | 228.0 | Compositional bias | Note=Asp/Glu-rich (highly acidic) |
| Hgene | ANP32E | chr1:150195513 | chr14:23532752 | ENST00000314136 | - | 6 | 7 | 215_268 | 245 | 269.0 | Region | Note=ZID domain |
| Hgene | ANP32E | chr1:150195513 | chr14:23532752 | ENST00000369119 | - | 6 | 7 | 215_268 | 197 | 221.0 | Region | Note=ZID domain |
| Hgene | ANP32E | chr1:150195513 | chr14:23532752 | ENST00000436748 | - | 5 | 6 | 215_268 | 204 | 228.0 | Region | Note=ZID domain |
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Fusion Gene Sequence for ANP32E-ACIN1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >4978_4978_1_ANP32E-ACIN1_ANP32E_chr1_150195513_ENST00000369119_ACIN1_chr14_23532752_ENST00000262710_length(transcript)=2586nt_BP=782nt GTCAGTCGGAGCGGCAGGTCGCGAGAGCAGGGCTGGTGGCCAGCGGGGAGCCTCGCAGAGGAAAGCATCAGTCTTGCTGAAATAAGCCTA GAATTGGAACGTGACAGAGTTAGTCCTTGATAATTGCCTGTGTGTCAATGGGGAAATTGAAGGCCTGAATGATACTTTCAAAGAACTAGA ATTTCTGAGTATGGCTAATGTGGAACTAAGTTCGCTGGCCCGGCTTCCCAGCTTAAATAAACTTCGAAAATTGGAGCTTAGTGATAATAT AATTTCTGGAGGCTTGGAAGTCCTGGCAGAGAAATGTCCAAATCTTACCTACCTCAATCTGAGTGGAAACAAAATAAAAGATCTCAGTAC AGTAGAAGCTCTGCAAAATCTTAAAAATTTGAAAAGTCTTGACCTGTTTAACTGTGAGATCACAAACCTGGAAGATTATAGAGAAAGTAT TTTTGAACTACTGCAGCAAATCACATACTTAGATGGATTTGATCAGGAGGATAATGAAGCGCCGGACTCTGAAGAGGAGGATGATGAGGA TGGCGATGAAGATGATGAAGAGGAAGAGGAAAATGAAGCTGGTCCACCGGAAGGATATGAGGAAGAGGAGGAGGAAGAGGAAGAGGAGGA TGAGGATGAGGATGAAGATGAAGATGAAGCAGGTTCAGAGTTGGGAGAGGGAGAAGAGGAAGTGGGCCTCTCATACTTAATGAAAGAAGA AATTCAGGATGAAGAAGATGATGATGACTATGTTGAAGAAGGGGAAGAAGAGGAAGAAGAGGATCGTTCAGAAAGAGGCAGAGCGGGCCG AACGGGCCAAGGAGCGGGAGAAGCGGCGAAAGGAGCAAGAAGAAGAAGAGCAAAAGGAGCGGGAGAAGGAAGCCGAGCGGGAACGGAACC GACAGCTGGAGCGAGAGAAACGTCGGGAGCACAGTCGGGAGAGGGACAGGGAGAGAGAGAGAGAAAGGGAGCGGGACAGGGGGGACCGAG ATCGGGATAGGGAAAGGGACCGAGAACGAGGCAGGGAAAGGGATCGCAGGGACACCAAGCGCCACAGCAGAAGCCGGAGTCGGAGCACAC CTGTGCGGGACCGGGGTGGGCGCCGCTAGCTGGGAAAACACTAGAGCTGCAGGTACCAGCCACTCGGCCCCAGGGGGTTATGGCCACAGA GGGATAGGCACAGTCTCCACCACCCTGGAGCCAAGGGTCTTTCACATCACCTATCCCTACATACATACCAAATGGAAAAGTGGCCATCCT TTTCCCCCCAAACACACCCCCTTAACCTATCTCTTGGGACTTAGCCCGACCCTCCCTCTCATTTCCCATTAAGTCTGAGAGGCAAGAGCT AGGTTAGGCAAGGAGGTGGTTGGCCAGAGATGGGGAACAGCCAGGTGCCCCAGTCCTCTGATTTTTCCTCCATCCTGCTTACCACCTCCC TGGGTACTTACAGCCTTCTCTTGGGAACAGCCGGGGCCAGGACTGGGTCACCTATGAGCTGAATCAGCATCTCCTCCTGAGTCCCAGGGC CCCTGCAGTTCCCAGTCTCTTCTGTCCTGCAGCCCTTGCCTCTTTCCCACAGGTTCCACTTTATATCCACCTTTTCCTTTTGTTCAATTT TTATTTTTATTTTTTTTATTATTAAATGATGTGGTCTATGGAAAAAAAAATAAAAATCTGACTTAGTTTTAGAAAGCCCAGGAGGAACCA CCTGCCAAGCTGCTGGATGACCTTTTCCGAAAGACCAAGGCAGCTCCCTGCATCTATTGGCTCCCACTGACTGACAGCCAGCTGGATTAT CACCGAGGCCTCTTGGTGGACCGTCCCTCTGAAACTAAGACAGAGGAGCAGGGAATACCACGGCCCCTGCACCCCCCACCCCCACCCCCG GTCCAGCCACCACAGCACCCCCGGGCAGAGCAGCGGGAGCAGGAACGGGCAGTGCGGGAACAGTGGGCAGAACGGGAACGGGAAATGGAG CGGCGGGAGCGGACTCGATCAGAGCGTGAATGGGATCGGGACAAAGTTCGAGAAGGGCCCCGTTCCCGATCAAGGTCCCGTGACCGCCGC CGCAAGGAACGTGCGAAGTCTAAAGAAAAGAAGAGTGAGAAGAAAGTACTCAACAGTAGAGGAAGCTGTTGCCACCCGCACAGCTCTGCA CGGGGTCAAATGGCCCCAGTCCAATCCCAAATTCCTTTGTGCTGACTATGCCGAGCAAGATGAGGTCCGTCCTTTCACTTTAGGCCAGCT AAAGGAGTTGTTGGGGCGCACAGGAACCTTGGTGGAAGAGGCCTTCTGGATTGACAAGATCAAATCTCATTGCTTTGTAACGTGACTTTA GGAGATACCTTAACTCGACGTTCCATTAGCCAGCAGAAGTCCGGAGTTTCCATTACCATTGATGACCCAGTCCGAACTGCCCAGGTGCCC TCCCCACCCCGGGGCAAGATTAGCAACATTGTCCATATCTCCAATTTGGGGAAGAAGAGGAAGAAGAGAAGGAACCTGAAGCAGAACCTC >4978_4978_1_ANP32E-ACIN1_ANP32E_chr1_150195513_ENST00000369119_ACIN1_chr14_23532752_ENST00000262710_length(amino acids)=290AA_BP=157 MCVNGEIEGLNDTFKELEFLSMANVELSSLARLPSLNKLRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKS LDLFNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGS ELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEDRSERGRAGRTGQGAGEAAKGARRRRAKGAGEGSRAGTEPTAGARETSGAQS -------------------------------------------------------------- >4978_4978_2_ANP32E-ACIN1_ANP32E_chr1_150195513_ENST00000369119_ACIN1_chr14_23532752_ENST00000338631_length(transcript)=2586nt_BP=782nt GTCAGTCGGAGCGGCAGGTCGCGAGAGCAGGGCTGGTGGCCAGCGGGGAGCCTCGCAGAGGAAAGCATCAGTCTTGCTGAAATAAGCCTA GAATTGGAACGTGACAGAGTTAGTCCTTGATAATTGCCTGTGTGTCAATGGGGAAATTGAAGGCCTGAATGATACTTTCAAAGAACTAGA ATTTCTGAGTATGGCTAATGTGGAACTAAGTTCGCTGGCCCGGCTTCCCAGCTTAAATAAACTTCGAAAATTGGAGCTTAGTGATAATAT AATTTCTGGAGGCTTGGAAGTCCTGGCAGAGAAATGTCCAAATCTTACCTACCTCAATCTGAGTGGAAACAAAATAAAAGATCTCAGTAC AGTAGAAGCTCTGCAAAATCTTAAAAATTTGAAAAGTCTTGACCTGTTTAACTGTGAGATCACAAACCTGGAAGATTATAGAGAAAGTAT TTTTGAACTACTGCAGCAAATCACATACTTAGATGGATTTGATCAGGAGGATAATGAAGCGCCGGACTCTGAAGAGGAGGATGATGAGGA TGGCGATGAAGATGATGAAGAGGAAGAGGAAAATGAAGCTGGTCCACCGGAAGGATATGAGGAAGAGGAGGAGGAAGAGGAAGAGGAGGA TGAGGATGAGGATGAAGATGAAGATGAAGCAGGTTCAGAGTTGGGAGAGGGAGAAGAGGAAGTGGGCCTCTCATACTTAATGAAAGAAGA AATTCAGGATGAAGAAGATGATGATGACTATGTTGAAGAAGGGGAAGAAGAGGAAGAAGAGGATCGTTCAGAAAGAGGCAGAGCGGGCCG AACGGGCCAAGGAGCGGGAGAAGCGGCGAAAGGAGCAAGAAGAAGAAGAGCAAAAGGAGCGGGAGAAGGAAGCCGAGCGGGAACGGAACC GACAGCTGGAGCGAGAGAAACGTCGGGAGCACAGTCGGGAGAGGGACAGGGAGAGAGAGAGAGAAAGGGAGCGGGACAGGGGGGACCGAG ATCGGGATAGGGAAAGGGACCGAGAACGAGGCAGGGAAAGGGATCGCAGGGACACCAAGCGCCACAGCAGAAGCCGGAGTCGGAGCACAC CTGTGCGGGACCGGGGTGGGCGCCGCTAGCTGGGAAAACACTAGAGCTGCAGGTACCAGCCACTCGGCCCCAGGGGGTTATGGCCACAGA GGGATAGGCACAGTCTCCACCACCCTGGAGCCAAGGGTCTTTCACATCACCTATCCCTACATACATACCAAATGGAAAAGTGGCCATCCT TTTCCCCCCAAACACACCCCCTTAACCTATCTCTTGGGACTTAGCCCGACCCTCCCTCTCATTTCCCATTAAGTCTGAGAGGCAAGAGCT AGGTTAGGCAAGGAGGTGGTTGGCCAGAGATGGGGAACAGCCAGGTGCCCCAGTCCTCTGATTTTTCCTCCATCCTGCTTACCACCTCCC TGGGTACTTACAGCCTTCTCTTGGGAACAGCCGGGGCCAGGACTGGGTCACCTATGAGCTGAATCAGCATCTCCTCCTGAGTCCCAGGGC CCCTGCAGTTCCCAGTCTCTTCTGTCCTGCAGCCCTTGCCTCTTTCCCACAGGTTCCACTTTATATCCACCTTTTCCTTTTGTTCAATTT TTATTTTTATTTTTTTTATTATTAAATGATGTGGTCTATGGAAAAAAAAATAAAAATCTGACTTAGTTTTAGAAAGCCCAGGAGGAACCA CCTGCCAAGCTGCTGGATGACCTTTTCCGAAAGACCAAGGCAGCTCCCTGCATCTATTGGCTCCCACTGACTGACAGCCAGCTGGATTAT CACCGAGGCCTCTTGGTGGACCGTCCCTCTGAAACTAAGACAGAGGAGCAGGGAATACCACGGCCCCTGCACCCCCCACCCCCACCCCCG GTCCAGCCACCACAGCACCCCCGGGCAGAGCAGCGGGAGCAGGAACGGGCAGTGCGGGAACAGTGGGCAGAACGGGAACGGGAAATGGAG CGGCGGGAGCGGACTCGATCAGAGCGTGAATGGGATCGGGACAAAGTTCGAGAAGGGCCCCGTTCCCGATCAAGGTCCCGTGACCGCCGC CGCAAGGAACGTGCGAAGTCTAAAGAAAAGAAGAGTGAGAAGAAAGTACTCAACAGTAGAGGAAGCTGTTGCCACCCGCACAGCTCTGCA CGGGGTCAAATGGCCCCAGTCCAATCCCAAATTCCTTTGTGCTGACTATGCCGAGCAAGATGAGGTCCGTCCTTTCACTTTAGGCCAGCT AAAGGAGTTGTTGGGGCGCACAGGAACCTTGGTGGAAGAGGCCTTCTGGATTGACAAGATCAAATCTCATTGCTTTGTAACGTGACTTTA GGAGATACCTTAACTCGACGTTCCATTAGCCAGCAGAAGTCCGGAGTTTCCATTACCATTGATGACCCAGTCCGAACTGCCCAGGTGCCC TCCCCACCCCGGGGCAAGATTAGCAACATTGTCCATATCTCCAATTTGGGGAAGAAGAGGAAGAAGAGAAGGAACCTGAAGCAGAACCTC >4978_4978_2_ANP32E-ACIN1_ANP32E_chr1_150195513_ENST00000369119_ACIN1_chr14_23532752_ENST00000338631_length(amino acids)=290AA_BP=157 MCVNGEIEGLNDTFKELEFLSMANVELSSLARLPSLNKLRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKS LDLFNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGS ELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEDRSERGRAGRTGQGAGEAAKGARRRRAKGAGEGSRAGTEPTAGARETSGAQS -------------------------------------------------------------- >4978_4978_3_ANP32E-ACIN1_ANP32E_chr1_150195513_ENST00000369119_ACIN1_chr14_23532752_ENST00000357481_length(transcript)=2586nt_BP=782nt GTCAGTCGGAGCGGCAGGTCGCGAGAGCAGGGCTGGTGGCCAGCGGGGAGCCTCGCAGAGGAAAGCATCAGTCTTGCTGAAATAAGCCTA GAATTGGAACGTGACAGAGTTAGTCCTTGATAATTGCCTGTGTGTCAATGGGGAAATTGAAGGCCTGAATGATACTTTCAAAGAACTAGA ATTTCTGAGTATGGCTAATGTGGAACTAAGTTCGCTGGCCCGGCTTCCCAGCTTAAATAAACTTCGAAAATTGGAGCTTAGTGATAATAT AATTTCTGGAGGCTTGGAAGTCCTGGCAGAGAAATGTCCAAATCTTACCTACCTCAATCTGAGTGGAAACAAAATAAAAGATCTCAGTAC AGTAGAAGCTCTGCAAAATCTTAAAAATTTGAAAAGTCTTGACCTGTTTAACTGTGAGATCACAAACCTGGAAGATTATAGAGAAAGTAT TTTTGAACTACTGCAGCAAATCACATACTTAGATGGATTTGATCAGGAGGATAATGAAGCGCCGGACTCTGAAGAGGAGGATGATGAGGA TGGCGATGAAGATGATGAAGAGGAAGAGGAAAATGAAGCTGGTCCACCGGAAGGATATGAGGAAGAGGAGGAGGAAGAGGAAGAGGAGGA TGAGGATGAGGATGAAGATGAAGATGAAGCAGGTTCAGAGTTGGGAGAGGGAGAAGAGGAAGTGGGCCTCTCATACTTAATGAAAGAAGA AATTCAGGATGAAGAAGATGATGATGACTATGTTGAAGAAGGGGAAGAAGAGGAAGAAGAGGATCGTTCAGAAAGAGGCAGAGCGGGCCG AACGGGCCAAGGAGCGGGAGAAGCGGCGAAAGGAGCAAGAAGAAGAAGAGCAAAAGGAGCGGGAGAAGGAAGCCGAGCGGGAACGGAACC GACAGCTGGAGCGAGAGAAACGTCGGGAGCACAGTCGGGAGAGGGACAGGGAGAGAGAGAGAGAAAGGGAGCGGGACAGGGGGGACCGAG ATCGGGATAGGGAAAGGGACCGAGAACGAGGCAGGGAAAGGGATCGCAGGGACACCAAGCGCCACAGCAGAAGCCGGAGTCGGAGCACAC CTGTGCGGGACCGGGGTGGGCGCCGCTAGCTGGGAAAACACTAGAGCTGCAGGTACCAGCCACTCGGCCCCAGGGGGTTATGGCCACAGA GGGATAGGCACAGTCTCCACCACCCTGGAGCCAAGGGTCTTTCACATCACCTATCCCTACATACATACCAAATGGAAAAGTGGCCATCCT TTTCCCCCCAAACACACCCCCTTAACCTATCTCTTGGGACTTAGCCCGACCCTCCCTCTCATTTCCCATTAAGTCTGAGAGGCAAGAGCT AGGTTAGGCAAGGAGGTGGTTGGCCAGAGATGGGGAACAGCCAGGTGCCCCAGTCCTCTGATTTTTCCTCCATCCTGCTTACCACCTCCC TGGGTACTTACAGCCTTCTCTTGGGAACAGCCGGGGCCAGGACTGGGTCACCTATGAGCTGAATCAGCATCTCCTCCTGAGTCCCAGGGC CCCTGCAGTTCCCAGTCTCTTCTGTCCTGCAGCCCTTGCCTCTTTCCCACAGGTTCCACTTTATATCCACCTTTTCCTTTTGTTCAATTT TTATTTTTATTTTTTTTATTATTAAATGATGTGGTCTATGGAAAAAAAAATAAAAATCTGACTTAGTTTTAGAAAGCCCAGGAGGAACCA CCTGCCAAGCTGCTGGATGACCTTTTCCGAAAGACCAAGGCAGCTCCCTGCATCTATTGGCTCCCACTGACTGACAGCCAGCTGGATTAT CACCGAGGCCTCTTGGTGGACCGTCCCTCTGAAACTAAGACAGAGGAGCAGGGAATACCACGGCCCCTGCACCCCCCACCCCCACCCCCG GTCCAGCCACCACAGCACCCCCGGGCAGAGCAGCGGGAGCAGGAACGGGCAGTGCGGGAACAGTGGGCAGAACGGGAACGGGAAATGGAG CGGCGGGAGCGGACTCGATCAGAGCGTGAATGGGATCGGGACAAAGTTCGAGAAGGGCCCCGTTCCCGATCAAGGTCCCGTGACCGCCGC CGCAAGGAACGTGCGAAGTCTAAAGAAAAGAAGAGTGAGAAGAAAGTACTCAACAGTAGAGGAAGCTGTTGCCACCCGCACAGCTCTGCA CGGGGTCAAATGGCCCCAGTCCAATCCCAAATTCCTTTGTGCTGACTATGCCGAGCAAGATGAGGTCCGTCCTTTCACTTTAGGCCAGCT AAAGGAGTTGTTGGGGCGCACAGGAACCTTGGTGGAAGAGGCCTTCTGGATTGACAAGATCAAATCTCATTGCTTTGTAACGTGACTTTA GGAGATACCTTAACTCGACGTTCCATTAGCCAGCAGAAGTCCGGAGTTTCCATTACCATTGATGACCCAGTCCGAACTGCCCAGGTGCCC TCCCCACCCCGGGGCAAGATTAGCAACATTGTCCATATCTCCAATTTGGGGAAGAAGAGGAAGAAGAGAAGGAACCTGAAGCAGAACCTC >4978_4978_3_ANP32E-ACIN1_ANP32E_chr1_150195513_ENST00000369119_ACIN1_chr14_23532752_ENST00000357481_length(amino acids)=290AA_BP=157 MCVNGEIEGLNDTFKELEFLSMANVELSSLARLPSLNKLRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKS LDLFNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGS ELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEDRSERGRAGRTGQGAGEAAKGARRRRAKGAGEGSRAGTEPTAGARETSGAQS -------------------------------------------------------------- >4978_4978_4_ANP32E-ACIN1_ANP32E_chr1_150195513_ENST00000369119_ACIN1_chr14_23532752_ENST00000397341_length(transcript)=2573nt_BP=782nt GTCAGTCGGAGCGGCAGGTCGCGAGAGCAGGGCTGGTGGCCAGCGGGGAGCCTCGCAGAGGAAAGCATCAGTCTTGCTGAAATAAGCCTA GAATTGGAACGTGACAGAGTTAGTCCTTGATAATTGCCTGTGTGTCAATGGGGAAATTGAAGGCCTGAATGATACTTTCAAAGAACTAGA ATTTCTGAGTATGGCTAATGTGGAACTAAGTTCGCTGGCCCGGCTTCCCAGCTTAAATAAACTTCGAAAATTGGAGCTTAGTGATAATAT AATTTCTGGAGGCTTGGAAGTCCTGGCAGAGAAATGTCCAAATCTTACCTACCTCAATCTGAGTGGAAACAAAATAAAAGATCTCAGTAC AGTAGAAGCTCTGCAAAATCTTAAAAATTTGAAAAGTCTTGACCTGTTTAACTGTGAGATCACAAACCTGGAAGATTATAGAGAAAGTAT TTTTGAACTACTGCAGCAAATCACATACTTAGATGGATTTGATCAGGAGGATAATGAAGCGCCGGACTCTGAAGAGGAGGATGATGAGGA TGGCGATGAAGATGATGAAGAGGAAGAGGAAAATGAAGCTGGTCCACCGGAAGGATATGAGGAAGAGGAGGAGGAAGAGGAAGAGGAGGA TGAGGATGAGGATGAAGATGAAGATGAAGCAGGTTCAGAGTTGGGAGAGGGAGAAGAGGAAGTGGGCCTCTCATACTTAATGAAAGAAGA AATTCAGGATGAAGAAGATGATGATGACTATGTTGAAGAAGGGGAAGAAGAGGAAGAAGAGGATCGTTCAGAAAGAGGCAGAGCGGGCCG AACGGGCCAAGGAGCGGGAGAAGCGGCGAAAGGAGCAAGAAGAAGAAGAGCAAAAGGAGCGGGAGAAGGAAGCCGAGCGGGAACGGAACC GACAGCTGGAGCGAGAGAAACGTCGGGAGCACAGTCGGGAGAGGGACAGGGAGAGAGAGAGAGAAAGGGAGCGGGACAGGGGGGACCGAG ATCGGGATAGGGAAAGGGACCGAGAACGAGGCAGGGAAAGGGATCGCAGGGACACCAAGCGCCACAGCAGAAGCCGGAGTCGGAGCACAC CTGTGCGGGACCGGGGTGGGCGCCGCTAGCTGGGAAAACACTAGAGCTGCAGGTACCAGCCACTCGGCCCCAGGGGGTTATGGCCACAGA GGGATAGGCACAGTCTCCACCACCCTGGAGCCAAGGGTCTTTCACATCACCTATCCCTACATACATACCAAATGGAAAAGTGGCCATCCT TTTCCCCCCAAACACACCCCCTTAACCTATCTCTTGGGACTTAGCCCGACCCTCCCTCTCATTTCCCATTAAGTCTGAGAGGCAAGAGCT AGGTTAGGCAAGGAGGTGGTTGGCCAGAGATGGGGAACAGCCAGGTGCCCCAGTCCTCTGATTTTTCCTCCATCCTGCTTACCACCTCCC TGGGTACTTACAGCCTTCTCTTGGGAACAGCCGGGGCCAGGACTGGGTCACCTATGAGCTGAATCAGCATCTCCTCCTGAGTCCCAGGGC CCCTGCAGTTCCCAGTCTCTTCTGTCCTGCAGCCCTTGCCTCTTTCCCACAGGTTCCACTTTATATCCACCTTTTCCTTTTGTTCAATTT TTATTTTTATTTTTTTTATTATTAAATGATGTGGTCTATGGAAAAAAAAATAAAAATAGAAAGCCCAGGAGGAACCACCTGCCAAGCTGC TGGATGACCTTTTCCGAAAGACCAAGGCAGCTCCCTGCATCTATTGGCTCCCACTGACTGACAGCCAGCTGGATTATCACCGAGGCCTCT TGGTGGACCGTCCCTCTGAAACTAAGACAGAGGAGCAGGGAATACCACGGCCCCTGCACCCCCCACCCCCACCCCCGGTCCAGCCACCAC AGCACCCCCGGGCAGAGCAGCGGGAGCAGGAACGGGCAGTGCGGGAACAGTGGGCAGAACGGGAACGGGAAATGGAGCGGCGGGAGCGGA CTCGATCAGAGCGTGAATGGGATCGGGACAAAGTTCGAGAAGGGCCCCGTTCCCGATCAAGGTCCCGTGACCGCCGCCGCAAGGAACGTG CGAAGTCTAAAGAAAAGAAGAGTGAGAAGAAAGTACTCAACAGTAGAGGAAGCTGTTGCCACCCGCACAGCTCTGCACGGGGTCAAATGG CCCCAGTCCAATCCCAAATTCCTTTGTGCTGACTATGCCGAGCAAGATGAGGTCCGTCCTTTCACTTTAGGCCAGCTAAAGGAGTTGTTG GGGCGCACAGGAACCTTGGTGGAAGAGGCCTTCTGGATTGACAAGATCAAATCTCATTGCTTTGTAACGTGACTTTAGGAGATACCTTAA CTCGACGTTCCATTAGCCAGCAGAAGTCCGGAGTTTCCATTACCATTGATGACCCAGTCCGAACTGCCCAGGTGCCCTCCCCACCCCGGG GCAAGATTAGCAACATTGTCCATATCTCCAATTTGGGGAAGAAGAGGAAGAAGAGAAGGAACCTGAAGCAGAACCTCCTGTACCTCCCCA >4978_4978_4_ANP32E-ACIN1_ANP32E_chr1_150195513_ENST00000369119_ACIN1_chr14_23532752_ENST00000397341_length(amino acids)=290AA_BP=157 MCVNGEIEGLNDTFKELEFLSMANVELSSLARLPSLNKLRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKS LDLFNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGS ELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEDRSERGRAGRTGQGAGEAAKGARRRRAKGAGEGSRAGTEPTAGARETSGAQS -------------------------------------------------------------- >4978_4978_5_ANP32E-ACIN1_ANP32E_chr1_150195513_ENST00000369119_ACIN1_chr14_23532752_ENST00000457657_length(transcript)=2586nt_BP=782nt GTCAGTCGGAGCGGCAGGTCGCGAGAGCAGGGCTGGTGGCCAGCGGGGAGCCTCGCAGAGGAAAGCATCAGTCTTGCTGAAATAAGCCTA GAATTGGAACGTGACAGAGTTAGTCCTTGATAATTGCCTGTGTGTCAATGGGGAAATTGAAGGCCTGAATGATACTTTCAAAGAACTAGA ATTTCTGAGTATGGCTAATGTGGAACTAAGTTCGCTGGCCCGGCTTCCCAGCTTAAATAAACTTCGAAAATTGGAGCTTAGTGATAATAT AATTTCTGGAGGCTTGGAAGTCCTGGCAGAGAAATGTCCAAATCTTACCTACCTCAATCTGAGTGGAAACAAAATAAAAGATCTCAGTAC AGTAGAAGCTCTGCAAAATCTTAAAAATTTGAAAAGTCTTGACCTGTTTAACTGTGAGATCACAAACCTGGAAGATTATAGAGAAAGTAT TTTTGAACTACTGCAGCAAATCACATACTTAGATGGATTTGATCAGGAGGATAATGAAGCGCCGGACTCTGAAGAGGAGGATGATGAGGA TGGCGATGAAGATGATGAAGAGGAAGAGGAAAATGAAGCTGGTCCACCGGAAGGATATGAGGAAGAGGAGGAGGAAGAGGAAGAGGAGGA TGAGGATGAGGATGAAGATGAAGATGAAGCAGGTTCAGAGTTGGGAGAGGGAGAAGAGGAAGTGGGCCTCTCATACTTAATGAAAGAAGA AATTCAGGATGAAGAAGATGATGATGACTATGTTGAAGAAGGGGAAGAAGAGGAAGAAGAGGATCGTTCAGAAAGAGGCAGAGCGGGCCG AACGGGCCAAGGAGCGGGAGAAGCGGCGAAAGGAGCAAGAAGAAGAAGAGCAAAAGGAGCGGGAGAAGGAAGCCGAGCGGGAACGGAACC GACAGCTGGAGCGAGAGAAACGTCGGGAGCACAGTCGGGAGAGGGACAGGGAGAGAGAGAGAGAAAGGGAGCGGGACAGGGGGGACCGAG ATCGGGATAGGGAAAGGGACCGAGAACGAGGCAGGGAAAGGGATCGCAGGGACACCAAGCGCCACAGCAGAAGCCGGAGTCGGAGCACAC CTGTGCGGGACCGGGGTGGGCGCCGCTAGCTGGGAAAACACTAGAGCTGCAGGTACCAGCCACTCGGCCCCAGGGGGTTATGGCCACAGA GGGATAGGCACAGTCTCCACCACCCTGGAGCCAAGGGTCTTTCACATCACCTATCCCTACATACATACCAAATGGAAAAGTGGCCATCCT TTTCCCCCCAAACACACCCCCTTAACCTATCTCTTGGGACTTAGCCCGACCCTCCCTCTCATTTCCCATTAAGTCTGAGAGGCAAGAGCT AGGTTAGGCAAGGAGGTGGTTGGCCAGAGATGGGGAACAGCCAGGTGCCCCAGTCCTCTGATTTTTCCTCCATCCTGCTTACCACCTCCC TGGGTACTTACAGCCTTCTCTTGGGAACAGCCGGGGCCAGGACTGGGTCACCTATGAGCTGAATCAGCATCTCCTCCTGAGTCCCAGGGC CCCTGCAGTTCCCAGTCTCTTCTGTCCTGCAGCCCTTGCCTCTTTCCCACAGGTTCCACTTTATATCCACCTTTTCCTTTTGTTCAATTT TTATTTTTATTTTTTTTATTATTAAATGATGTGGTCTATGGAAAAAAAAATAAAAATCTGACTTAGTTTTAGAAAGCCCAGGAGGAACCA CCTGCCAAGCTGCTGGATGACCTTTTCCGAAAGACCAAGGCAGCTCCCTGCATCTATTGGCTCCCACTGACTGACAGCCAGCTGGATTAT CACCGAGGCCTCTTGGTGGACCGTCCCTCTGAAACTAAGACAGAGGAGCAGGGAATACCACGGCCCCTGCACCCCCCACCCCCACCCCCG GTCCAGCCACCACAGCACCCCCGGGCAGAGCAGCGGGAGCAGGAACGGGCAGTGCGGGAACAGTGGGCAGAACGGGAACGGGAAATGGAG CGGCGGGAGCGGACTCGATCAGAGCGTGAATGGGATCGGGACAAAGTTCGAGAAGGGCCCCGTTCCCGATCAAGGTCCCGTGACCGCCGC CGCAAGGAACGTGCGAAGTCTAAAGAAAAGAAGAGTGAGAAGAAAGTACTCAACAGTAGAGGAAGCTGTTGCCACCCGCACAGCTCTGCA CGGGGTCAAATGGCCCCAGTCCAATCCCAAATTCCTTTGTGCTGACTATGCCGAGCAAGATGAGGTCCGTCCTTTCACTTTAGGCCAGCT AAAGGAGTTGTTGGGGCGCACAGGAACCTTGGTGGAAGAGGCCTTCTGGATTGACAAGATCAAATCTCATTGCTTTGTAACGTGACTTTA GGAGATACCTTAACTCGACGTTCCATTAGCCAGCAGAAGTCCGGAGTTTCCATTACCATTGATGACCCAGTCCGAACTGCCCAGGTGCCC TCCCCACCCCGGGGCAAGATTAGCAACATTGTCCATATCTCCAATTTGGGGAAGAAGAGGAAGAAGAGAAGGAACCTGAAGCAGAACCTC >4978_4978_5_ANP32E-ACIN1_ANP32E_chr1_150195513_ENST00000369119_ACIN1_chr14_23532752_ENST00000457657_length(amino acids)=290AA_BP=157 MCVNGEIEGLNDTFKELEFLSMANVELSSLARLPSLNKLRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKS LDLFNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGS ELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEDRSERGRAGRTGQGAGEAAKGARRRRAKGAGEGSRAGTEPTAGARETSGAQS -------------------------------------------------------------- >4978_4978_6_ANP32E-ACIN1_ANP32E_chr1_150195513_ENST00000369119_ACIN1_chr14_23532752_ENST00000555053_length(transcript)=2094nt_BP=782nt GTCAGTCGGAGCGGCAGGTCGCGAGAGCAGGGCTGGTGGCCAGCGGGGAGCCTCGCAGAGGAAAGCATCAGTCTTGCTGAAATAAGCCTA GAATTGGAACGTGACAGAGTTAGTCCTTGATAATTGCCTGTGTGTCAATGGGGAAATTGAAGGCCTGAATGATACTTTCAAAGAACTAGA ATTTCTGAGTATGGCTAATGTGGAACTAAGTTCGCTGGCCCGGCTTCCCAGCTTAAATAAACTTCGAAAATTGGAGCTTAGTGATAATAT AATTTCTGGAGGCTTGGAAGTCCTGGCAGAGAAATGTCCAAATCTTACCTACCTCAATCTGAGTGGAAACAAAATAAAAGATCTCAGTAC AGTAGAAGCTCTGCAAAATCTTAAAAATTTGAAAAGTCTTGACCTGTTTAACTGTGAGATCACAAACCTGGAAGATTATAGAGAAAGTAT TTTTGAACTACTGCAGCAAATCACATACTTAGATGGATTTGATCAGGAGGATAATGAAGCGCCGGACTCTGAAGAGGAGGATGATGAGGA TGGCGATGAAGATGATGAAGAGGAAGAGGAAAATGAAGCTGGTCCACCGGAAGGATATGAGGAAGAGGAGGAGGAAGAGGAAGAGGAGGA TGAGGATGAGGATGAAGATGAAGATGAAGCAGGTTCAGAGTTGGGAGAGGGAGAAGAGGAAGTGGGCCTCTCATACTTAATGAAAGAAGA AATTCAGGATGAAGAAGATGATGATGACTATGTTGAAGAAGGGGAAGAAGAGGAAGAAGAGGATCGTTCAGAAAGAGGCAGAGCGGGCCG AACGGGCCAAGGAGCGGGAGAAGCGGCGAAAGGAGCAAGAAGAAGAAGAGCAAAAGGAGCGGGAGAAGGAAGCCGAGCGGGAACGGAACC GACAGCTGGAGCGAGAGAAACGTCGGGAGCACAGTCGGGAGAGGGACAGGGAGAGAGAGAGAGAAAGGGAGCGGGACAGGGGGGACCGAG ATCGGGATAGGGAAAGGGACCGAGAACGAGGCAGGGAAAGGGATCGCAGGGACACCAAGCGCCACAGCAGAAGCCGGAGTCGGAGCACAC CTGTGCGGGACCGGGGTGGGCGCCGCTAGCTGGGAAAACACTAGAGCTGCAGGTACCAGCCACTCGGCCCCAGGGGGTTATGGCCACAGA GGGATAGGCACAGTCTCCACCACCCTGGAGAAAGCCCAGGAGGAACCACCTGCCAAGCTGCTGGATGACCTTTTCCGAAAGACCAAGGCA GCTCCCTGCATCTATTGGCTCCCACTGACTGACAGCCAGCTGGATTATCACCGAGGCCTCTTGGTGGACCGTCCCTCTGAAACTAAGACA GAGGAGCAGGGAATACCACGGCCCCTGCACCCCCCACCCCCACCCCCGGTCCAGCCACCACAGCACCCCCGGGCAGAGCAGCGGGAGCAG GAACGGGCAGTGCGGGAACAGTGGGCAGAACGGGAACGGGAAATGGAGCGGCGGGAGCGGACTCGATCAGAGCGTGAATGGGATCGGGAC AAAGTTCGAGAAGGGCCCCGTTCCCGATCAAGGTCCCGTGACCGCCGCCGCAAGGAACGTGCGAAGTCTAAAGAAAAGAAGAGTGAGAAG AAAGTACTCAACAGTAGAGGAAGCTGTTGCCACCCGCACAGCTCTGCACGGGGTCAAATGGCCCCAGTCCAATCCCAAATTCCTTTGTGC TGACTATGCCGAGCAAGATGAGGTCCGTCCTTTCACTTTAGGCCAGCTAAAGGAGTTGTTGGGGCGCACAGGAACCTTGGTGGAAGAGGC CTTCTGGATTGACAAGATCAAATCTCATTGCTTTGTAACGTGACTTTAGGAGATACCTTAACTCGACGTTCCATTAGCCAGCAGAAGTCC GGAGTTTCCATTACCATTGATGACCCAGTCCGAACTGCCCAGGTGCCCTCCCCACCCCGGGGCAAGATTAGCAACATTGTCCATATCTCC AATTTGGGGAAGAAGAGGAAGAAGAGAAGGAACCTGAAGCAGAACCTCCTGTACCTCCCCAGGTGTCAGTAGAGGTGGCCTTGCCCCCAC >4978_4978_6_ANP32E-ACIN1_ANP32E_chr1_150195513_ENST00000369119_ACIN1_chr14_23532752_ENST00000555053_length(amino acids)=290AA_BP=157 MCVNGEIEGLNDTFKELEFLSMANVELSSLARLPSLNKLRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKS LDLFNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGS ELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEDRSERGRAGRTGQGAGEAAKGARRRRAKGAGEGSRAGTEPTAGARETSGAQS -------------------------------------------------------------- >4978_4978_7_ANP32E-ACIN1_ANP32E_chr1_150195513_ENST00000369119_ACIN1_chr14_23532752_ENST00000557515_length(transcript)=2589nt_BP=782nt GTCAGTCGGAGCGGCAGGTCGCGAGAGCAGGGCTGGTGGCCAGCGGGGAGCCTCGCAGAGGAAAGCATCAGTCTTGCTGAAATAAGCCTA GAATTGGAACGTGACAGAGTTAGTCCTTGATAATTGCCTGTGTGTCAATGGGGAAATTGAAGGCCTGAATGATACTTTCAAAGAACTAGA ATTTCTGAGTATGGCTAATGTGGAACTAAGTTCGCTGGCCCGGCTTCCCAGCTTAAATAAACTTCGAAAATTGGAGCTTAGTGATAATAT AATTTCTGGAGGCTTGGAAGTCCTGGCAGAGAAATGTCCAAATCTTACCTACCTCAATCTGAGTGGAAACAAAATAAAAGATCTCAGTAC AGTAGAAGCTCTGCAAAATCTTAAAAATTTGAAAAGTCTTGACCTGTTTAACTGTGAGATCACAAACCTGGAAGATTATAGAGAAAGTAT TTTTGAACTACTGCAGCAAATCACATACTTAGATGGATTTGATCAGGAGGATAATGAAGCGCCGGACTCTGAAGAGGAGGATGATGAGGA TGGCGATGAAGATGATGAAGAGGAAGAGGAAAATGAAGCTGGTCCACCGGAAGGATATGAGGAAGAGGAGGAGGAAGAGGAAGAGGAGGA TGAGGATGAGGATGAAGATGAAGATGAAGCAGGTTCAGAGTTGGGAGAGGGAGAAGAGGAAGTGGGCCTCTCATACTTAATGAAAGAAGA AATTCAGGATGAAGAAGATGATGATGACTATGTTGAAGAAGGGGAAGAAGAGGAAGAAGAGGATCGTTCAGAAAGAGGCAGAGCGGGCCG AACGGGCCAAGGAGCGGGAGAAGCGGCGAAAGGAGCAAGAAGAAGAAGAGCAAAAGGAGCGGGAGAAGGAAGCCGAGCGGGAACGGAACC GACAGCTGGAGCGAGAGAAACGTCGGGAGCACAGTCGGGAGAGGGACAGGGAGAGAGAGAGAGAAAGGGAGCGGGACAGGGGGGACCGAG ATCGGGATAGGGAAAGGGACCGAGAACGAGGCAGGGAAAGGGATCGCAGGGACACCAAGCGCCACAGCAGAAGCCGGAGTCGGAGCACAC CTGTGCGGGACCGGGGTGGGCGCCGCTAGCTGGGAAAACACTAGAGCTGCAGGTACCAGCCACTCGGCCCCAGGGGGTTATGGCCACAGA GGGATAGGCACAGTCTCCACCACCCTGGAGCCAAGGGTCTTTCACATCACCTATCCCTACATACATACCAAATGGAAAAGTGGCCATCCT TTTCCCCCCAAACACACCCCCTTAACCTATCTCTTGGGACTTAGCCCGACCCTCCCTCTCATTTCCCATTAAGTCTGAGAGGCAAGAGCT AGGTTAGGCAAGGAGGTGGTTGGCCAGAGATGGGGAACAGCCAGGTGCCCCAGTCCTCTGATTTTTCCTCCATCCTGCTTACCACCTCCC TGGGTACTTACAGCCTTCTCTTGGGAACAGCCGGGGCCAGGACTGGGTCACCTATGAGCTGAATCAGCATCTCCTCCTGAGTCCCAGGGC CCCTGCAGTTCCCAGTCTCTTCTGTCCTGCAGCCCTTGCCTCTTTCCCACAGGTTCCACTTTATATCCACCTTTTCCTTTTGTTCAATTT TTATTTTTATTTTTTTTATTATTAAATGATGTGGTCTATGGAAAAAAAAATAAAAATCTGACTTAGTTTTAAAAGAAAGCCCAGGAGGAA CCACCTGCCAAGCTGCTGGATGACCTTTTCCGAAAGACCAAGGCAGCTCCCTGCATCTATTGGCTCCCACTGACTGACAGCCAGCTGGAT TATCACCGAGGCCTCTTGGTGGACCGTCCCTCTGAAACTAAGACAGAGGAGCAGGGAATACCACGGCCCCTGCACCCCCCACCCCCACCC CCGGTCCAGCCACCACAGCACCCCCGGGCAGAGCAGCGGGAGCAGGAACGGGCAGTGCGGGAACAGTGGGCAGAACGGGAACGGGAAATG GAGCGGCGGGAGCGGACTCGATCAGAGCGTGAATGGGATCGGGACAAAGTTCGAGAAGGGCCCCGTTCCCGATCAAGGTCCCGTGACCGC CGCCGCAAGGAACGTGCGAAGTCTAAAGAAAAGAAGAGTGAGAAGAAAGTACTCAACAGTAGAGGAAGCTGTTGCCACCCGCACAGCTCT GCACGGGGTCAAATGGCCCCAGTCCAATCCCAAATTCCTTTGTGCTGACTATGCCGAGCAAGATGAGGTCCGTCCTTTCACTTTAGGCCA GCTAAAGGAGTTGTTGGGGCGCACAGGAACCTTGGTGGAAGAGGCCTTCTGGATTGACAAGATCAAATCTCATTGCTTTGTAACGTGACT TTAGGAGATACCTTAACTCGACGTTCCATTAGCCAGCAGAAGTCCGGAGTTTCCATTACCATTGATGACCCAGTCCGAACTGCCCAGGTG CCCTCCCCACCCCGGGGCAAGATTAGCAACATTGTCCATATCTCCAATTTGGGGAAGAAGAGGAAGAAGAGAAGGAACCTGAAGCAGAAC >4978_4978_7_ANP32E-ACIN1_ANP32E_chr1_150195513_ENST00000369119_ACIN1_chr14_23532752_ENST00000557515_length(amino acids)=290AA_BP=157 MCVNGEIEGLNDTFKELEFLSMANVELSSLARLPSLNKLRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKS LDLFNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGS ELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEDRSERGRAGRTGQGAGEAAKGARRRRAKGAGEGSRAGTEPTAGARETSGAQS -------------------------------------------------------------- >4978_4978_8_ANP32E-ACIN1_ANP32E_chr1_150195513_ENST00000369119_ACIN1_chr14_23532752_ENST00000605057_length(transcript)=2586nt_BP=782nt GTCAGTCGGAGCGGCAGGTCGCGAGAGCAGGGCTGGTGGCCAGCGGGGAGCCTCGCAGAGGAAAGCATCAGTCTTGCTGAAATAAGCCTA GAATTGGAACGTGACAGAGTTAGTCCTTGATAATTGCCTGTGTGTCAATGGGGAAATTGAAGGCCTGAATGATACTTTCAAAGAACTAGA ATTTCTGAGTATGGCTAATGTGGAACTAAGTTCGCTGGCCCGGCTTCCCAGCTTAAATAAACTTCGAAAATTGGAGCTTAGTGATAATAT AATTTCTGGAGGCTTGGAAGTCCTGGCAGAGAAATGTCCAAATCTTACCTACCTCAATCTGAGTGGAAACAAAATAAAAGATCTCAGTAC AGTAGAAGCTCTGCAAAATCTTAAAAATTTGAAAAGTCTTGACCTGTTTAACTGTGAGATCACAAACCTGGAAGATTATAGAGAAAGTAT TTTTGAACTACTGCAGCAAATCACATACTTAGATGGATTTGATCAGGAGGATAATGAAGCGCCGGACTCTGAAGAGGAGGATGATGAGGA TGGCGATGAAGATGATGAAGAGGAAGAGGAAAATGAAGCTGGTCCACCGGAAGGATATGAGGAAGAGGAGGAGGAAGAGGAAGAGGAGGA TGAGGATGAGGATGAAGATGAAGATGAAGCAGGTTCAGAGTTGGGAGAGGGAGAAGAGGAAGTGGGCCTCTCATACTTAATGAAAGAAGA AATTCAGGATGAAGAAGATGATGATGACTATGTTGAAGAAGGGGAAGAAGAGGAAGAAGAGGATCGTTCAGAAAGAGGCAGAGCGGGCCG AACGGGCCAAGGAGCGGGAGAAGCGGCGAAAGGAGCAAGAAGAAGAAGAGCAAAAGGAGCGGGAGAAGGAAGCCGAGCGGGAACGGAACC GACAGCTGGAGCGAGAGAAACGTCGGGAGCACAGTCGGGAGAGGGACAGGGAGAGAGAGAGAGAAAGGGAGCGGGACAGGGGGGACCGAG ATCGGGATAGGGAAAGGGACCGAGAACGAGGCAGGGAAAGGGATCGCAGGGACACCAAGCGCCACAGCAGAAGCCGGAGTCGGAGCACAC CTGTGCGGGACCGGGGTGGGCGCCGCTAGCTGGGAAAACACTAGAGCTGCAGGTACCAGCCACTCGGCCCCAGGGGGTTATGGCCACAGA GGGATAGGCACAGTCTCCACCACCCTGGAGCCAAGGGTCTTTCACATCACCTATCCCTACATACATACCAAATGGAAAAGTGGCCATCCT TTTCCCCCCAAACACACCCCCTTAACCTATCTCTTGGGACTTAGCCCGACCCTCCCTCTCATTTCCCATTAAGTCTGAGAGGCAAGAGCT AGGTTAGGCAAGGAGGTGGTTGGCCAGAGATGGGGAACAGCCAGGTGCCCCAGTCCTCTGATTTTTCCTCCATCCTGCTTACCACCTCCC TGGGTACTTACAGCCTTCTCTTGGGAACAGCCGGGGCCAGGACTGGGTCACCTATGAGCTGAATCAGCATCTCCTCCTGAGTCCCAGGGC CCCTGCAGTTCCCAGTCTCTTCTGTCCTGCAGCCCTTGCCTCTTTCCCACAGGTTCCACTTTATATCCACCTTTTCCTTTTGTTCAATTT TTATTTTTATTTTTTTTATTATTAAATGATGTGGTCTATGGAAAAAAAAATAAAAATCTGACTTAGTTTTAGAAAGCCCAGGAGGAACCA CCTGCCAAGCTGCTGGATGACCTTTTCCGAAAGACCAAGGCAGCTCCCTGCATCTATTGGCTCCCACTGACTGACAGCCAGCTGGATTAT CACCGAGGCCTCTTGGTGGACCGTCCCTCTGAAACTAAGACAGAGGAGCAGGGAATACCACGGCCCCTGCACCCCCCACCCCCACCCCCG GTCCAGCCACCACAGCACCCCCGGGCAGAGCAGCGGGAGCAGGAACGGGCAGTGCGGGAACAGTGGGCAGAACGGGAACGGGAAATGGAG CGGCGGGAGCGGACTCGATCAGAGCGTGAATGGGATCGGGACAAAGTTCGAGAAGGGCCCCGTTCCCGATCAAGGTCCCGTGACCGCCGC CGCAAGGAACGTGCGAAGTCTAAAGAAAAGAAGAGTGAGAAGAAAGTACTCAACAGTAGAGGAAGCTGTTGCCACCCGCACAGCTCTGCA CGGGGTCAAATGGCCCCAGTCCAATCCCAAATTCCTTTGTGCTGACTATGCCGAGCAAGATGAGGTCCGTCCTTTCACTTTAGGCCAGCT AAAGGAGTTGTTGGGGCGCACAGGAACCTTGGTGGAAGAGGCCTTCTGGATTGACAAGATCAAATCTCATTGCTTTGTAACGTGACTTTA GGAGATACCTTAACTCGACGTTCCATTAGCCAGCAGAAGTCCGGAGTTTCCATTACCATTGATGACCCAGTCCGAACTGCCCAGGTGCCC TCCCCACCCCGGGGCAAGATTAGCAACATTGTCCATATCTCCAATTTGGGGAAGAAGAGGAAGAAGAGAAGGAACCTGAAGCAGAACCTC >4978_4978_8_ANP32E-ACIN1_ANP32E_chr1_150195513_ENST00000369119_ACIN1_chr14_23532752_ENST00000605057_length(amino acids)=290AA_BP=157 MCVNGEIEGLNDTFKELEFLSMANVELSSLARLPSLNKLRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKS LDLFNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGS ELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEDRSERGRAGRTGQGAGEAAKGARRRRAKGAGEGSRAGTEPTAGARETSGAQS -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for ANP32E-ACIN1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for ANP32E-ACIN1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for ANP32E-ACIN1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | C3714756 | Intellectual Disability | 1 | GENOMICS_ENGLAND |
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