Fusion Gene Studies
in Kim Lab

FusionBase FusionGDB FusionGDB2 FusionPDB FusionNeoAntigen FusionAI FusionNW FGviewer Publication Contact
FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:ADAMTS12-RAI14 (FusionGDB2 ID:HG81792TG26064)

Fusion Gene Summary for ADAMTS12-RAI14

check button Fusion gene summary
Fusion gene informationFusion gene name: ADAMTS12-RAI14
Fusion gene ID: hg81792tg26064
HgeneTgene
Gene symbol

ADAMTS12

RAI14

Gene ID

81792

26064

Gene nameADAM metallopeptidase with thrombospondin type 1 motif 12retinoic acid induced 14
SynonymsPRO4389NORPEG|RAI13
Cytomap('ADAMTS12')('RAI14')

5p13.3-p13.2

5p13.2

Type of geneprotein-codingprotein-coding
DescriptionA disintegrin and metalloproteinase with thrombospondin motifs 12ADAM-TS 12ADAM-TS12ADAMTS-12a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 12ankycorbinankyrin repeat and coiled-coil structure-containing proteinnovel retinal pigment epithelial cell proteinretinoic acid-induced protein 14
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000352040, ENST00000504830, 
ENST00000515401, ENST00000504582, 
Fusion gene scores* DoF score6 X 6 X 4=14410 X 8 X 7=560
# samples 612
** MAII scorelog2(6/144*10)=-1.26303440583379
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(12/560*10)=-2.22239242133645
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ADAMTS12 [Title/Abstract] AND RAI14 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointADAMTS12(33881224)-RAI14(34757573), # samples:3
Anticipated loss of major functional domain due to fusion event.ADAMTS12-RAI14 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ADAMTS12-RAI14 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ADAMTS12-RAI14 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
ADAMTS12-RAI14 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneADAMTS12

GO:0030167

proteoglycan catabolic process

17895370

HgeneADAMTS12

GO:0032331

negative regulation of chondrocyte differentiation

22247065

HgeneADAMTS12

GO:0050727

regulation of inflammatory response

23019333

HgeneADAMTS12

GO:0051603

proteolysis involved in cellular protein catabolic process

16611630

HgeneADAMTS12

GO:0071773

cellular response to BMP stimulus

22247065

HgeneADAMTS12

GO:1901509

regulation of endothelial tube morphogenesis

17895370

HgeneADAMTS12

GO:1902203

negative regulation of hepatocyte growth factor receptor signaling pathway

17895370

HgeneADAMTS12

GO:1902548

negative regulation of cellular response to vascular endothelial growth factor stimulus

17895370

HgeneADAMTS12

GO:2001113

negative regulation of cellular response to hepatocyte growth factor stimulus

17895370


check buttonFusion gene breakpoints across ADAMTS12 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across RAI14 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4SKCMTCGA-EB-A44Q-06AADAMTS12chr5

33881224

-RAI14chr5

34757573

+


Top

Fusion Gene ORF analysis for ADAMTS12-RAI14

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000352040ENST00000397449ADAMTS12chr5

33881224

-RAI14chr5

34757573

+
5CDS-3UTRENST00000352040ENST00000507276ADAMTS12chr5

33881224

-RAI14chr5

34757573

+
5CDS-3UTRENST00000504830ENST00000397449ADAMTS12chr5

33881224

-RAI14chr5

34757573

+
5CDS-3UTRENST00000504830ENST00000507276ADAMTS12chr5

33881224

-RAI14chr5

34757573

+
5CDS-3UTRENST00000515401ENST00000397449ADAMTS12chr5

33881224

-RAI14chr5

34757573

+
5CDS-3UTRENST00000515401ENST00000507276ADAMTS12chr5

33881224

-RAI14chr5

34757573

+
In-frameENST00000352040ENST00000265109ADAMTS12chr5

33881224

-RAI14chr5

34757573

+
In-frameENST00000352040ENST00000428746ADAMTS12chr5

33881224

-RAI14chr5

34757573

+
In-frameENST00000352040ENST00000503673ADAMTS12chr5

33881224

-RAI14chr5

34757573

+
In-frameENST00000352040ENST00000506376ADAMTS12chr5

33881224

-RAI14chr5

34757573

+
In-frameENST00000352040ENST00000512629ADAMTS12chr5

33881224

-RAI14chr5

34757573

+
In-frameENST00000352040ENST00000515799ADAMTS12chr5

33881224

-RAI14chr5

34757573

+
In-frameENST00000504830ENST00000265109ADAMTS12chr5

33881224

-RAI14chr5

34757573

+
In-frameENST00000504830ENST00000428746ADAMTS12chr5

33881224

-RAI14chr5

34757573

+
In-frameENST00000504830ENST00000503673ADAMTS12chr5

33881224

-RAI14chr5

34757573

+
In-frameENST00000504830ENST00000506376ADAMTS12chr5

33881224

-RAI14chr5

34757573

+
In-frameENST00000504830ENST00000512629ADAMTS12chr5

33881224

-RAI14chr5

34757573

+
In-frameENST00000504830ENST00000515799ADAMTS12chr5

33881224

-RAI14chr5

34757573

+
In-frameENST00000515401ENST00000265109ADAMTS12chr5

33881224

-RAI14chr5

34757573

+
In-frameENST00000515401ENST00000428746ADAMTS12chr5

33881224

-RAI14chr5

34757573

+
In-frameENST00000515401ENST00000503673ADAMTS12chr5

33881224

-RAI14chr5

34757573

+
In-frameENST00000515401ENST00000506376ADAMTS12chr5

33881224

-RAI14chr5

34757573

+
In-frameENST00000515401ENST00000512629ADAMTS12chr5

33881224

-RAI14chr5

34757573

+
In-frameENST00000515401ENST00000515799ADAMTS12chr5

33881224

-RAI14chr5

34757573

+
intron-3CDSENST00000504582ENST00000265109ADAMTS12chr5

33881224

-RAI14chr5

34757573

+
intron-3CDSENST00000504582ENST00000428746ADAMTS12chr5

33881224

-RAI14chr5

34757573

+
intron-3CDSENST00000504582ENST00000503673ADAMTS12chr5

33881224

-RAI14chr5

34757573

+
intron-3CDSENST00000504582ENST00000506376ADAMTS12chr5

33881224

-RAI14chr5

34757573

+
intron-3CDSENST00000504582ENST00000512629ADAMTS12chr5

33881224

-RAI14chr5

34757573

+
intron-3CDSENST00000504582ENST00000515799ADAMTS12chr5

33881224

-RAI14chr5

34757573

+
intron-3UTRENST00000504582ENST00000397449ADAMTS12chr5

33881224

-RAI14chr5

34757573

+
intron-3UTRENST00000504582ENST00000507276ADAMTS12chr5

33881224

-RAI14chr5

34757573

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000504830ADAMTS12chr533881224-ENST00000265109RAI14chr534757573+559482533637311131
ENST00000504830ADAMTS12chr533881224-ENST00000512629RAI14chr534757573+364582533636441102
ENST00000504830ADAMTS12chr533881224-ENST00000428746RAI14chr534757573+557882533637311131
ENST00000504830ADAMTS12chr533881224-ENST00000503673RAI14chr534757573+377282533637311131
ENST00000504830ADAMTS12chr533881224-ENST00000515799RAI14chr534757573+377482533637311131
ENST00000504830ADAMTS12chr533881224-ENST00000506376RAI14chr534757573+375282533637311131
ENST00000352040ADAMTS12chr533881224-ENST00000265109RAI14chr534757573+53435748534801131
ENST00000352040ADAMTS12chr533881224-ENST00000512629RAI14chr534757573+33945748533931103
ENST00000352040ADAMTS12chr533881224-ENST00000428746RAI14chr534757573+53275748534801131
ENST00000352040ADAMTS12chr533881224-ENST00000503673RAI14chr534757573+35215748534801131
ENST00000352040ADAMTS12chr533881224-ENST00000515799RAI14chr534757573+35235748534801131
ENST00000352040ADAMTS12chr533881224-ENST00000506376RAI14chr534757573+35015748534801131
ENST00000515401ADAMTS12chr533881224-ENST00000265109RAI14chr534757573+542165216335581131
ENST00000515401ADAMTS12chr533881224-ENST00000512629RAI14chr534757573+347265216334711103
ENST00000515401ADAMTS12chr533881224-ENST00000428746RAI14chr534757573+540565216335581131
ENST00000515401ADAMTS12chr533881224-ENST00000503673RAI14chr534757573+359965216335581131
ENST00000515401ADAMTS12chr533881224-ENST00000515799RAI14chr534757573+360165216335581131
ENST00000515401ADAMTS12chr533881224-ENST00000506376RAI14chr534757573+357965216335581131

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000504830ENST00000265109ADAMTS12chr533881224-RAI14chr534757573+0.0007109030.99928904
ENST00000504830ENST00000512629ADAMTS12chr533881224-RAI14chr534757573+0.0010228670.9989772
ENST00000504830ENST00000428746ADAMTS12chr533881224-RAI14chr534757573+0.0007154460.99928457
ENST00000504830ENST00000503673ADAMTS12chr533881224-RAI14chr534757573+0.0017862050.99821377
ENST00000504830ENST00000515799ADAMTS12chr533881224-RAI14chr534757573+0.0017735210.99822646
ENST00000504830ENST00000506376ADAMTS12chr533881224-RAI14chr534757573+0.0018402960.9981597
ENST00000352040ENST00000265109ADAMTS12chr533881224-RAI14chr534757573+0.0005451710.9994548
ENST00000352040ENST00000512629ADAMTS12chr533881224-RAI14chr534757573+0.0008137070.99918634
ENST00000352040ENST00000428746ADAMTS12chr533881224-RAI14chr534757573+0.0005498180.99945015
ENST00000352040ENST00000503673ADAMTS12chr533881224-RAI14chr534757573+0.0014035570.9985965
ENST00000352040ENST00000515799ADAMTS12chr533881224-RAI14chr534757573+0.0013919450.99860805
ENST00000352040ENST00000506376ADAMTS12chr533881224-RAI14chr534757573+0.0014520410.998548
ENST00000515401ENST00000265109ADAMTS12chr533881224-RAI14chr534757573+0.0006078990.99939203
ENST00000515401ENST00000512629ADAMTS12chr533881224-RAI14chr534757573+0.00088230.9991177
ENST00000515401ENST00000428746ADAMTS12chr533881224-RAI14chr534757573+0.0006130580.9993869
ENST00000515401ENST00000503673ADAMTS12chr533881224-RAI14chr534757573+0.0015371560.9984629
ENST00000515401ENST00000515799ADAMTS12chr533881224-RAI14chr534757573+0.0015246090.9984754
ENST00000515401ENST00000506376ADAMTS12chr533881224-RAI14chr534757573+0.0015916240.9984084

Top

Fusion Genomic Features for ADAMTS12-RAI14


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
ADAMTS12chr533881223-RAI14chr534757572+3.94E-111
ADAMTS12chr533881223-RAI14chr534757572+3.94E-111

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

Top

Fusion Protein Features for ADAMTS12-RAI14


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr5:33881224/chr5:34757573)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneRAI14chr5:33881224chr5:34757573ENST00000265109118349_37412981.0Coiled coilOntology_term=ECO:0000255
TgeneRAI14chr5:33881224chr5:34757573ENST00000265109118425_94712981.0Coiled coilOntology_term=ECO:0000255
TgeneRAI14chr5:33881224chr5:34757573ENST00000428746118349_37412981.0Coiled coilOntology_term=ECO:0000255
TgeneRAI14chr5:33881224chr5:34757573ENST00000428746118425_94712981.0Coiled coilOntology_term=ECO:0000255
TgeneRAI14chr5:33881224chr5:34757573ENST00000503673219349_37412981.0Coiled coilOntology_term=ECO:0000255
TgeneRAI14chr5:33881224chr5:34757573ENST00000503673219425_94712981.0Coiled coilOntology_term=ECO:0000255
TgeneRAI14chr5:33881224chr5:34757573ENST00000506376017349_3744973.0Coiled coilOntology_term=ECO:0000255
TgeneRAI14chr5:33881224chr5:34757573ENST00000506376017425_9474973.0Coiled coilOntology_term=ECO:0000255
TgeneRAI14chr5:33881224chr5:34757573ENST00000512629117349_37412952.0Coiled coilOntology_term=ECO:0000255
TgeneRAI14chr5:33881224chr5:34757573ENST00000512629117425_94712952.0Coiled coilOntology_term=ECO:0000255
TgeneRAI14chr5:33881224chr5:34757573ENST00000515799320349_37415984.0Coiled coilOntology_term=ECO:0000255
TgeneRAI14chr5:33881224chr5:34757573ENST00000515799320425_94715984.0Coiled coilOntology_term=ECO:0000255
TgeneRAI14chr5:33881224chr5:34757573ENST00000265109118270_27612981.0MotifNuclear localization signal
TgeneRAI14chr5:33881224chr5:34757573ENST00000428746118270_27612981.0MotifNuclear localization signal
TgeneRAI14chr5:33881224chr5:34757573ENST00000503673219270_27612981.0MotifNuclear localization signal
TgeneRAI14chr5:33881224chr5:34757573ENST00000506376017270_2764973.0MotifNuclear localization signal
TgeneRAI14chr5:33881224chr5:34757573ENST00000512629117270_27612952.0MotifNuclear localization signal
TgeneRAI14chr5:33881224chr5:34757573ENST00000515799320270_27615984.0MotifNuclear localization signal
TgeneRAI14chr5:33881224chr5:34757573ENST00000265109118118_14712981.0RepeatNote=ANK 4
TgeneRAI14chr5:33881224chr5:34757573ENST00000265109118151_18012981.0RepeatNote=ANK 5
TgeneRAI14chr5:33881224chr5:34757573ENST00000265109118184_21312981.0RepeatNote=ANK 6
TgeneRAI14chr5:33881224chr5:34757573ENST0000026510911818_5112981.0RepeatNote=ANK 1
TgeneRAI14chr5:33881224chr5:34757573ENST00000265109118217_24712981.0RepeatNote=ANK 7
TgeneRAI14chr5:33881224chr5:34757573ENST0000026510911852_8112981.0RepeatNote=ANK 2
TgeneRAI14chr5:33881224chr5:34757573ENST0000026510911885_11412981.0RepeatNote=ANK 3
TgeneRAI14chr5:33881224chr5:34757573ENST00000428746118118_14712981.0RepeatNote=ANK 4
TgeneRAI14chr5:33881224chr5:34757573ENST00000428746118151_18012981.0RepeatNote=ANK 5
TgeneRAI14chr5:33881224chr5:34757573ENST00000428746118184_21312981.0RepeatNote=ANK 6
TgeneRAI14chr5:33881224chr5:34757573ENST0000042874611818_5112981.0RepeatNote=ANK 1
TgeneRAI14chr5:33881224chr5:34757573ENST00000428746118217_24712981.0RepeatNote=ANK 7
TgeneRAI14chr5:33881224chr5:34757573ENST0000042874611852_8112981.0RepeatNote=ANK 2
TgeneRAI14chr5:33881224chr5:34757573ENST0000042874611885_11412981.0RepeatNote=ANK 3
TgeneRAI14chr5:33881224chr5:34757573ENST00000503673219118_14712981.0RepeatNote=ANK 4
TgeneRAI14chr5:33881224chr5:34757573ENST00000503673219151_18012981.0RepeatNote=ANK 5
TgeneRAI14chr5:33881224chr5:34757573ENST00000503673219184_21312981.0RepeatNote=ANK 6
TgeneRAI14chr5:33881224chr5:34757573ENST0000050367321918_5112981.0RepeatNote=ANK 1
TgeneRAI14chr5:33881224chr5:34757573ENST00000503673219217_24712981.0RepeatNote=ANK 7
TgeneRAI14chr5:33881224chr5:34757573ENST0000050367321952_8112981.0RepeatNote=ANK 2
TgeneRAI14chr5:33881224chr5:34757573ENST0000050367321985_11412981.0RepeatNote=ANK 3
TgeneRAI14chr5:33881224chr5:34757573ENST00000506376017118_1474973.0RepeatNote=ANK 4
TgeneRAI14chr5:33881224chr5:34757573ENST00000506376017151_1804973.0RepeatNote=ANK 5
TgeneRAI14chr5:33881224chr5:34757573ENST00000506376017184_2134973.0RepeatNote=ANK 6
TgeneRAI14chr5:33881224chr5:34757573ENST0000050637601718_514973.0RepeatNote=ANK 1
TgeneRAI14chr5:33881224chr5:34757573ENST00000506376017217_2474973.0RepeatNote=ANK 7
TgeneRAI14chr5:33881224chr5:34757573ENST0000050637601752_814973.0RepeatNote=ANK 2
TgeneRAI14chr5:33881224chr5:34757573ENST0000050637601785_1144973.0RepeatNote=ANK 3
TgeneRAI14chr5:33881224chr5:34757573ENST00000512629117118_14712952.0RepeatNote=ANK 4
TgeneRAI14chr5:33881224chr5:34757573ENST00000512629117151_18012952.0RepeatNote=ANK 5
TgeneRAI14chr5:33881224chr5:34757573ENST00000512629117184_21312952.0RepeatNote=ANK 6
TgeneRAI14chr5:33881224chr5:34757573ENST0000051262911718_5112952.0RepeatNote=ANK 1
TgeneRAI14chr5:33881224chr5:34757573ENST00000512629117217_24712952.0RepeatNote=ANK 7
TgeneRAI14chr5:33881224chr5:34757573ENST0000051262911752_8112952.0RepeatNote=ANK 2
TgeneRAI14chr5:33881224chr5:34757573ENST0000051262911785_11412952.0RepeatNote=ANK 3
TgeneRAI14chr5:33881224chr5:34757573ENST00000515799320118_14715984.0RepeatNote=ANK 4
TgeneRAI14chr5:33881224chr5:34757573ENST00000515799320151_18015984.0RepeatNote=ANK 5
TgeneRAI14chr5:33881224chr5:34757573ENST00000515799320184_21315984.0RepeatNote=ANK 6
TgeneRAI14chr5:33881224chr5:34757573ENST0000051579932018_5115984.0RepeatNote=ANK 1
TgeneRAI14chr5:33881224chr5:34757573ENST00000515799320217_24715984.0RepeatNote=ANK 7
TgeneRAI14chr5:33881224chr5:34757573ENST0000051579932052_8115984.0RepeatNote=ANK 2
TgeneRAI14chr5:33881224chr5:34757573ENST0000051579932085_11415984.0RepeatNote=ANK 3

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneADAMTS12chr5:33881224chr5:34757573ENST00000352040-222302_3051631510.0Compositional biasNote=Poly-Glu
HgeneADAMTS12chr5:33881224chr5:34757573ENST00000352040-222597_7001631510.0Compositional biasNote=Cys-rich
HgeneADAMTS12chr5:33881224chr5:34757573ENST00000504830-224302_3051631595.0Compositional biasNote=Poly-Glu
HgeneADAMTS12chr5:33881224chr5:34757573ENST00000504830-224597_7001631595.0Compositional biasNote=Cys-rich
HgeneADAMTS12chr5:33881224chr5:34757573ENST00000352040-2221313_13661631510.0DomainTSP type-1 5
HgeneADAMTS12chr5:33881224chr5:34757573ENST00000352040-2221368_14221631510.0DomainTSP type-1 6
HgeneADAMTS12chr5:33881224chr5:34757573ENST00000352040-2221423_14711631510.0DomainTSP type-1 7
HgeneADAMTS12chr5:33881224chr5:34757573ENST00000352040-2221472_15321631510.0DomainTSP type-1 8
HgeneADAMTS12chr5:33881224chr5:34757573ENST00000352040-2221535_15751631510.0DomainPLAC
HgeneADAMTS12chr5:33881224chr5:34757573ENST00000352040-222246_4561631510.0DomainPeptidase M12B
HgeneADAMTS12chr5:33881224chr5:34757573ENST00000352040-222465_5441631510.0DomainNote=Disintegrin
HgeneADAMTS12chr5:33881224chr5:34757573ENST00000352040-222542_5971631510.0DomainTSP type-1 1
HgeneADAMTS12chr5:33881224chr5:34757573ENST00000352040-222823_8831631510.0DomainTSP type-1 2
HgeneADAMTS12chr5:33881224chr5:34757573ENST00000352040-222887_9431631510.0DomainTSP type-1 3
HgeneADAMTS12chr5:33881224chr5:34757573ENST00000352040-222944_9971631510.0DomainTSP type-1 4
HgeneADAMTS12chr5:33881224chr5:34757573ENST00000504830-2241313_13661631595.0DomainTSP type-1 5
HgeneADAMTS12chr5:33881224chr5:34757573ENST00000504830-2241368_14221631595.0DomainTSP type-1 6
HgeneADAMTS12chr5:33881224chr5:34757573ENST00000504830-2241423_14711631595.0DomainTSP type-1 7
HgeneADAMTS12chr5:33881224chr5:34757573ENST00000504830-2241472_15321631595.0DomainTSP type-1 8
HgeneADAMTS12chr5:33881224chr5:34757573ENST00000504830-2241535_15751631595.0DomainPLAC
HgeneADAMTS12chr5:33881224chr5:34757573ENST00000504830-224246_4561631595.0DomainPeptidase M12B
HgeneADAMTS12chr5:33881224chr5:34757573ENST00000504830-224465_5441631595.0DomainNote=Disintegrin
HgeneADAMTS12chr5:33881224chr5:34757573ENST00000504830-224542_5971631595.0DomainTSP type-1 1
HgeneADAMTS12chr5:33881224chr5:34757573ENST00000504830-224823_8831631595.0DomainTSP type-1 2
HgeneADAMTS12chr5:33881224chr5:34757573ENST00000504830-224887_9431631595.0DomainTSP type-1 3
HgeneADAMTS12chr5:33881224chr5:34757573ENST00000504830-224944_9971631595.0DomainTSP type-1 4
HgeneADAMTS12chr5:33881224chr5:34757573ENST00000352040-222208_2131631510.0MotifCysteine switch
HgeneADAMTS12chr5:33881224chr5:34757573ENST00000504830-224208_2131631595.0MotifCysteine switch
HgeneADAMTS12chr5:33881224chr5:34757573ENST00000352040-222701_8271631510.0RegionNote=Spacer 1
HgeneADAMTS12chr5:33881224chr5:34757573ENST00000352040-222997_13161631510.0RegionNote=Spacer 2
HgeneADAMTS12chr5:33881224chr5:34757573ENST00000504830-224701_8271631595.0RegionNote=Spacer 1
HgeneADAMTS12chr5:33881224chr5:34757573ENST00000504830-224997_13161631595.0RegionNote=Spacer 2


Top

Fusion Gene Sequence for ADAMTS12-RAI14


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>2045_2045_1_ADAMTS12-RAI14_ADAMTS12_chr5_33881224_ENST00000352040_RAI14_chr5_34757573_ENST00000265109_length(transcript)=5343nt_BP=574nt
TCCTGCTGGGCCACAGGCGAGCGCTTTATTTCTGGAGCTGAGGGCTAAAACTTTTTTGACTTTTCTTCTCCTCAACATCTGAATCATGCC
ATGTGCCCAGAGGAGCTGGCTTGCAAACCTTTCCGTGGTGGCTCAGCTCCTTAACTTTGGGGCGCTTTGCTATGGGAGACAGCCTCAGCC
AGGCCCGGTTCGCTTCCCGGACAGGAGGCAAGAGCATTTTATCAAGGGCCTGCCAGAATACCACGTGGTGGGTCCAGTCCGAGTAGATGC
CAGTGGGCATTTTTTGTCATATGGCTTGCACTATCCCATCACGAGCAGCAGGAGGAAGAGAGATTTGGATGGCTCAGAGGACTGGGTGTA
CTACAGAATTTCTCACGAGGAGAAGGACCTGTTTTTTAACTTGACGGTCAATCAAGGATTTCTTTCCAATAGCTACATCATGGAGAAGAG
ATATGGGAACCTCTCCCATGTTAAGATGATGGCTTCCTCTGCCCCCCTCTGCCATCTCAGTGGCACGGTTCTACAGCAGGGCACCAGAGT
TGGGACGGCAGCCCTCAGTGCCTGCCATGGACTGACCAATGAGTGGAACAAGAATGATGACCGGCTACTGCAGGCCGTGGAGAATGGAGA
TGCGGAGAAGGTGGCCTCACTGCTCGGCAAGAAGGGGGCCAGTGCCACCAAACACGACAGTGAGGGCAAGACCGCTTTCCATCTTGCTGC
TGCAAAAGGACACGTGGAATGCCTCAGGGTCATGATTACACATGGTGTGGATGTGACAGCCCAAGATACTACCGGACACAGCGCCTTACA
TCTCGCAGCCAAGAACAGCCACCATGAATGCATCAGGAAGCTGCTTCAGTCTAAATGCCCAGCCGAAAGTGTCGACAGCTCTGGGAAAAC
AGCTTTACATTATGCAGCGGCTCAGGGCTGCCTTCAAGCTGTGCAGATTCTCTGCGAACACAAGAGCCCCATAAACCTCAAAGATTTGGA
TGGGAATATACCGCTGCTTCTTGCTGTACAAAATGGTCACAGTGAGATCTGTCACTTTCTCCTGGATCATGGAGCAGATGTCAATTCCAG
GAACAAAAGTGGAAGAACTGCTCTCATGCTGGCCTGTGAGATTGGCAGCTCTAACGCTGTGGAAGCCTTAATTAAAAAGGGTGCAGACCT
AAACCTTGTAGATTCTCTTGGATACAATGCCTTACATTATTCCAAACTCTCAGAAAATGCAGGAATTCAAAGCCTTCTATTATCAAAAAT
CTCTCAGGATGCTGATTTAAAGACCCCAACAAAACCAAAGCAGCATGACCAAGTCTCTAAAATAAGCTCAGAAAGAAGTGGAACTCCAAA
AAAACGCAAAGCTCCACCACCTCCTATCAGTCCTACCCAGTTGAGTGATGTCTCTTCCCCAAGATCAATAACTTCGACTCCACTATCGGG
AAAGGAATCGGTATTTTTTGCTGAACCACCCTTCAAGGCTGAGATCAGTTCTATACGAGAAAACAAAGACAGACTAAGTGACAGTACTAC
AGGTGCTGATAGCTTATTGGATATAAGTTCTGAAGCTGACCAACAAGATCTTCTCTCTCTATTGCAAGCAAAAGTTGCTTCCCTTACCTT
ACACAATAAGGAGTTACAAGATAAATTACAGGCCAAATCACCCAAGGAGGCGGAAGCAGACCTAAGCTTTGACTCATACCATTCCACCCA
AACTGACTTGGGCCCATCCCTGGGAAAACCTGGTGAAACCTCTCCCCCAGACTCCAAATCATCTCCATCTGTCTTAATACATTCTTTAGG
TAAATCCACTACTGACAATGATGTCAGAATTCAGCAACTGCAAGAGATTTTGCAAGATCTACAGAAGAGATTAGAGAGCTCTGAAGCAGA
GAGAAAACAGCTACAGGTCGAACTCCAATCCCGAAGGGCAGAACTGGTATGCTTAAACAACACTGAGATTTCAGAGAACAGCTCTGACCT
CAGCCAGAAACTTAAAGAAACTCAGAGCAAATACGAGGAGGCTATGAAAGAAGTCCTTAGTGTGCAGAAGCAGATGAAACTCGGTCTTGT
CTCACCTGAAAGCATGGATAATTATTCACATTTCCACGAGCTGAGGGTCACGGAAGAGGAAATAAATGTGCTAAAGCAGGATCTGCAGAA
TGCATTAGAAGAAAGTGAAAGAAATAAAGAGAAAGTGAGAGAGTTAGAGGAAAAACTGGTAGAGAGGGAGAAAGGTACAGTGATTAAGCC
ACCTGTGGAAGAGTACGAGGAAATGAAAAGTTCATATTGCTCTGTTATTGAGAATATGAATAAGGAGAAAGCATTTTTGTTTGAGAAATA
CCAAGAAGCCCAAGAAGAAATCATGAAATTAAAAGACACACTAAAAAGTCAGATGACACAGGAAGCCAGTGATGAAGCTGAGGACATGAA
AGAAGCCATGAATAGGATGATAGATGAACTCAATAAACAGGTGAGCGAGCTGTCACAGCTGTACAAAGAAGCCCAGGCTGAGCTGGAGGA
TTACAGGAAGAGGAAATCTCTAGAGGATGTCACAGCTGAATATATCCATAAAGCAGAGCATGAGAAACTGATGCAATTGACAAACGTGTC
CAGGGCTAAAGCAGAAGATGCACTGTCTGAAATGAAGTCTCAGTATTCAAAAGTGTTGAATGAGTTGACCCAGCTCAAACAACTGGTGGA
TGCACAAAAAGAGAACTCTGTCTCTATCACAGAACATTTGCAAGTGATAACCACGCTGCGGACTGCAGCAAAAGAGATGGAAGAAAAAAT
AAGCAATCTTAAGGAACACCTTGCAAGCAAGGAAGTGGAAGTAGCAAAGCTGGAGAAACAACTCTTAGAAGAGAAAGCTGCTATGACTGA
TGCAATGGTACCTCGGTCTTCCTATGAAAAACTCCAGTCATCCTTAGAGAGTGAAGTGAGTGTGTTGGCATCGAAATTAAAGGAATCTGT
GAAAGAGAAAGAGAAGGTCCATTCAGAGGTTGTCCAGATTAGAAGTGAGGTCTCACAGGTGAAAAGAGAAAAGGAAAATATTCAGACTCT
CTTGAAATCCAAAGAGCAAGAAGTAAATGAACTTCTGCAAAAATTCCAGCAAGCTCAGGAAGAACTTGCAGAAATGAAAAGATACGCTGA
GAGCTCTTCAAAACTGGAGGAAGATAAAGATAAAAAGATAAATGAGATGTCGAAGGAAGTCACCAAATTGAAGGAGGCCTTGAACAGCCT
CTCCCAGCTCTCCTACTCAACAAGCTCATCCAAAAGGCAGAGTCAGCAGCTGGAGGCGCTGCAGCAGCAAGTCAAACAGCTCCAGAACCA
GCTGGCGGAATGCAAGAAACAACACCAGGAGGTCATATCAGTTTACAGAATGCATCTTCTGTATGCTGTGCAGGGCCAGATGGATGAAGA
TGTCCAGAAAGTACTGAAGCAAATCCTTACCATGTGTAAAAACCAGTCTCAAAAGAAGTAAAGTGGATTCCTTGGCAGGACACTGCCCCT
TGTCATCTGTCTTTGTGTTAGATCCAGAGTTGTCGGCAGCCGCTGCCATTGTTCTCATTCGTGGTATGCACTGTGGCCTAGCGTAGCTTC
TTCCCTTTCCAAAGGTTTCTGAGGACTTCTCCCAGGAGAAGACTGCCCGCCTCAGAACTGCTTAGAGACTTCAAACCAGCAGAGGTGAAA
GTCCCTGTCATCCCTTCAGATTCCAGAGCTGGGATCAGCCATGCCCAGAGGTCTGGTCCTGATGCTGGCAGGGGGGCCCCCTCCTCCATC
CCTGACTGGCTGAGTGGCTTTATCACCACCGAGTGATGTGCTGAGGCCTCCTGCAGTGAATGCTCCTTCCATTCCTGTACTCGGGCAGTG
CCATTCAGCACAGGAGAGCTCTTTTTGCCTTTGGCTTTCAATTCCAAAACATGATTTAATTTCTAACTAAATTAGTATGGCACTAGTTAT
GAAGTATCTGCTTAAAACCCTTCATCATGATATCCTGTGGATTTAAAAACTCTAATTCCATGTTTTCTTCCCATCTGCCTTATATATCTC
ATCACCCTGCTTATCAATATTCAGTTTGATGAGCACTATTAACTAAAATATGAAACTTAAAAACAAAAGCAAGTTGTCCTTAAAAGTTCT
TTTTTTAAGTAAATTGTTGACATACTGCAAATTTTCTATGCAAACTTGCCTCCTGCTGTTATCTGTGAAGCTCAGGAAATCCAAACATTT
GTGTTTCAACAAGGGACAGTAAACTGTGTGTTTACAGCCAAAAGAAATGCCTCATAGTTCTTAACCTCAACTTTTGTAGAAGTATTTTTT
TCTCTGTAATATTTTTATTGGCTCATAAAGATGTTTTCATATCTGAACTCCTAAATAAGTGAAATTACAGTAGATTATATTAACAAAATA
CTTTTTAGGTAGCCATGCTTGAGACTTTTTAAAAATATAACTTTTTCCTTAAAGTTTTCAGCTATAGCAAAAGGTAGTTATGTATGCCAG
ACCTAATATGAGCTGCCACCAACACCCCTAGAACTTTCAGCCATGGTGTCTTCAGAATTGTAGCGCATTTCTGAATCTAGCAAATCCTCC
TTTTACCCGTTGAATGTTTTGAATGCCCTGACTCTACCAGCGCCCATAAATGATCTCTAGAAGGACTGTTAGTACCAATCTGTTTTTCAA
CTTTGAAGCTAAAAACCCTGATATGGTAATATTATGGTGCATAGCAGAGGTCTCGGAAAAAAAATATTTCTGTTCACTTTACTTTCAGGT
TAAAAATGTTTCTAACACGCTTGCAACTTCCCTTATGGCATTAATCTTGTTGAGGGAGAGAGACAGAATCCTGGACTCTCCAAAGTATTT
AACTGAAAGTAGGGCCTGCTCTGACAGGGCCCATGTCCCACAAGGCTGCTTGGCCTCAGTGGGTGCTTGGCTGTGCTGGATGATATGTTG
ATCTGTATTGGATAAGGACCAATGACAGCAAAGCAAAAATGGCTTTAAAGCTTGGTGTTACTTTTCTTAAGTTGTTTAATTATAGTTAAG
CAATTTCAAAAATGCTCCAAAGAAATGTGAAAGGACCTTTTGTCACAGCACTTCAGAAAATACACAACAGCCCCTTCTGCCCCCGCACAG
AAATGCTGCAGAGTATATAAAACTTGAGACATTTTTGTAGGATGCCTGACGAGGTGTAGCCTTTTATCTTGTTTCCGGATGCATATTTAT
TACGAGTACTCTGGTTAAATATTGAAAAGTTATATGCTGTAGTTTTTAGTATTTTGTCTTTGTAATTTACAGAAGTTATTGGAGAAAATA
AACTTGTTTCATTTTGCATTTCTGGTGTTGATT

>2045_2045_1_ADAMTS12-RAI14_ADAMTS12_chr5_33881224_ENST00000352040_RAI14_chr5_34757573_ENST00000265109_length(amino acids)=1131AA_BP=163
MPCAQRSWLANLSVVAQLLNFGALCYGRQPQPGPVRFPDRRQEHFIKGLPEYHVVGPVRVDASGHFLSYGLHYPITSSRRKRDLDGSEDW
VYYRISHEEKDLFFNLTVNQGFLSNSYIMEKRYGNLSHVKMMASSAPLCHLSGTVLQQGTRVGTAALSACHGLTNEWNKNDDRLLQAVEN
GDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSG
KTALHYAAAQGCLQAVQILCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEALIKKGA
DLNLVDSLGYNALHYSKLSENAGIQSLLLSKISQDADLKTPTKPKQHDQVSKISSERSGTPKKRKAPPPPISPTQLSDVSSPRSITSTPL
SGKESVFFAEPPFKAEISSIRENKDRLSDSTTGADSLLDISSEADQQDLLSLLQAKVASLTLHNKELQDKLQAKSPKEAEADLSFDSYHS
TQTDLGPSLGKPGETSPPDSKSSPSVLIHSLGKSTTDNDVRIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNNTEISENSS
DLSQKLKETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNYSHFHELRVTEEEINVLKQDLQNALEESERNKEKVRELEEKLVEREKGTVI
KPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAEL
EDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEE
KISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIRSEVSQVKREKENIQ
TLLKSKEQEVNELLQKFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQ
NQLAECKKQHQEVISVYRMHLLYAVQGQMDEDVQKVLKQILTMCKNQSQKK

--------------------------------------------------------------
>2045_2045_2_ADAMTS12-RAI14_ADAMTS12_chr5_33881224_ENST00000352040_RAI14_chr5_34757573_ENST00000428746_length(transcript)=5327nt_BP=574nt
TCCTGCTGGGCCACAGGCGAGCGCTTTATTTCTGGAGCTGAGGGCTAAAACTTTTTTGACTTTTCTTCTCCTCAACATCTGAATCATGCC
ATGTGCCCAGAGGAGCTGGCTTGCAAACCTTTCCGTGGTGGCTCAGCTCCTTAACTTTGGGGCGCTTTGCTATGGGAGACAGCCTCAGCC
AGGCCCGGTTCGCTTCCCGGACAGGAGGCAAGAGCATTTTATCAAGGGCCTGCCAGAATACCACGTGGTGGGTCCAGTCCGAGTAGATGC
CAGTGGGCATTTTTTGTCATATGGCTTGCACTATCCCATCACGAGCAGCAGGAGGAAGAGAGATTTGGATGGCTCAGAGGACTGGGTGTA
CTACAGAATTTCTCACGAGGAGAAGGACCTGTTTTTTAACTTGACGGTCAATCAAGGATTTCTTTCCAATAGCTACATCATGGAGAAGAG
ATATGGGAACCTCTCCCATGTTAAGATGATGGCTTCCTCTGCCCCCCTCTGCCATCTCAGTGGCACGGTTCTACAGCAGGGCACCAGAGT
TGGGACGGCAGCCCTCAGTGCCTGCCATGGACTGACCAATGAGTGGAACAAGAATGATGACCGGCTACTGCAGGCCGTGGAGAATGGAGA
TGCGGAGAAGGTGGCCTCACTGCTCGGCAAGAAGGGGGCCAGTGCCACCAAACACGACAGTGAGGGCAAGACCGCTTTCCATCTTGCTGC
TGCAAAAGGACACGTGGAATGCCTCAGGGTCATGATTACACATGGTGTGGATGTGACAGCCCAAGATACTACCGGACACAGCGCCTTACA
TCTCGCAGCCAAGAACAGCCACCATGAATGCATCAGGAAGCTGCTTCAGTCTAAATGCCCAGCCGAAAGTGTCGACAGCTCTGGGAAAAC
AGCTTTACATTATGCAGCGGCTCAGGGCTGCCTTCAAGCTGTGCAGATTCTCTGCGAACACAAGAGCCCCATAAACCTCAAAGATTTGGA
TGGGAATATACCGCTGCTTCTTGCTGTACAAAATGGTCACAGTGAGATCTGTCACTTTCTCCTGGATCATGGAGCAGATGTCAATTCCAG
GAACAAAAGTGGAAGAACTGCTCTCATGCTGGCCTGTGAGATTGGCAGCTCTAACGCTGTGGAAGCCTTAATTAAAAAGGGTGCAGACCT
AAACCTTGTAGATTCTCTTGGATACAATGCCTTACATTATTCCAAACTCTCAGAAAATGCAGGAATTCAAAGCCTTCTATTATCAAAAAT
CTCTCAGGATGCTGATTTAAAGACCCCAACAAAACCAAAGCAGCATGACCAAGTCTCTAAAATAAGCTCAGAAAGAAGTGGAACTCCAAA
AAAACGCAAAGCTCCACCACCTCCTATCAGTCCTACCCAGTTGAGTGATGTCTCTTCCCCAAGATCAATAACTTCGACTCCACTATCGGG
AAAGGAATCGGTATTTTTTGCTGAACCACCCTTCAAGGCTGAGATCAGTTCTATACGAGAAAACAAAGACAGACTAAGTGACAGTACTAC
AGGTGCTGATAGCTTATTGGATATAAGTTCTGAAGCTGACCAACAAGATCTTCTCTCTCTATTGCAAGCAAAAGTTGCTTCCCTTACCTT
ACACAATAAGGAGTTACAAGATAAATTACAGGCCAAATCACCCAAGGAGGCGGAAGCAGACCTAAGCTTTGACTCATACCATTCCACCCA
AACTGACTTGGGCCCATCCCTGGGAAAACCTGGTGAAACCTCTCCCCCAGACTCCAAATCATCTCCATCTGTCTTAATACATTCTTTAGG
TAAATCCACTACTGACAATGATGTCAGAATTCAGCAACTGCAAGAGATTTTGCAAGATCTACAGAAGAGATTAGAGAGCTCTGAAGCAGA
GAGAAAACAGCTACAGGTCGAACTCCAATCCCGAAGGGCAGAACTGGTATGCTTAAACAACACTGAGATTTCAGAGAACAGCTCTGACCT
CAGCCAGAAACTTAAAGAAACTCAGAGCAAATACGAGGAGGCTATGAAAGAAGTCCTTAGTGTGCAGAAGCAGATGAAACTCGGTCTTGT
CTCACCTGAAAGCATGGATAATTATTCACATTTCCACGAGCTGAGGGTCACGGAAGAGGAAATAAATGTGCTAAAGCAGGATCTGCAGAA
TGCATTAGAAGAAAGTGAAAGAAATAAAGAGAAAGTGAGAGAGTTAGAGGAAAAACTGGTAGAGAGGGAGAAAGGTACAGTGATTAAGCC
ACCTGTGGAAGAGTACGAGGAAATGAAAAGTTCATATTGCTCTGTTATTGAGAATATGAATAAGGAGAAAGCATTTTTGTTTGAGAAATA
CCAAGAAGCCCAAGAAGAAATCATGAAATTAAAAGACACACTAAAAAGTCAGATGACACAGGAAGCCAGTGATGAAGCTGAGGACATGAA
AGAAGCCATGAATAGGATGATAGATGAACTCAATAAACAGGTGAGCGAGCTGTCACAGCTGTACAAAGAAGCCCAGGCTGAGCTGGAGGA
TTACAGGAAGAGGAAATCTCTAGAGGATGTCACAGCTGAATATATCCATAAAGCAGAGCATGAGAAACTGATGCAATTGACAAACGTGTC
CAGGGCTAAAGCAGAAGATGCACTGTCTGAAATGAAGTCTCAGTATTCAAAAGTGTTGAATGAGTTGACCCAGCTCAAACAACTGGTGGA
TGCACAAAAAGAGAACTCTGTCTCTATCACAGAACATTTGCAAGTGATAACCACGCTGCGGACTGCAGCAAAAGAGATGGAAGAAAAAAT
AAGCAATCTTAAGGAACACCTTGCAAGCAAGGAAGTGGAAGTAGCAAAGCTGGAGAAACAACTCTTAGAAGAGAAAGCTGCTATGACTGA
TGCAATGGTACCTCGGTCTTCCTATGAAAAACTCCAGTCATCCTTAGAGAGTGAAGTGAGTGTGTTGGCATCGAAATTAAAGGAATCTGT
GAAAGAGAAAGAGAAGGTCCATTCAGAGGTTGTCCAGATTAGAAGTGAGGTCTCACAGGTGAAAAGAGAAAAGGAAAATATTCAGACTCT
CTTGAAATCCAAAGAGCAAGAAGTAAATGAACTTCTGCAAAAATTCCAGCAAGCTCAGGAAGAACTTGCAGAAATGAAAAGATACGCTGA
GAGCTCTTCAAAACTGGAGGAAGATAAAGATAAAAAGATAAATGAGATGTCGAAGGAAGTCACCAAATTGAAGGAGGCCTTGAACAGCCT
CTCCCAGCTCTCCTACTCAACAAGCTCATCCAAAAGGCAGAGTCAGCAGCTGGAGGCGCTGCAGCAGCAAGTCAAACAGCTCCAGAACCA
GCTGGCGGAATGCAAGAAACAACACCAGGAGGTCATATCAGTTTACAGAATGCATCTTCTGTATGCTGTGCAGGGCCAGATGGATGAAGA
TGTCCAGAAAGTACTGAAGCAAATCCTTACCATGTGTAAAAACCAGTCTCAAAAGAAGTAAAGTGGATTCCTTGGCAGGACACTGCCCCT
TGTCATCTGTCTTTGTGTTAGATCCAGAGTTGTCGGCAGCCGCTGCCATTGTTCTCATTCGTGGTATGCACTGTGGCCTAGCGTAGCTTC
TTCCCTTTCCAAAGGTTTCTGAGGACTTCTCCCAGGAGAAGACTGCCCGCCTCAGAACTGCTTAGAGACTTCAAACCAGCAGAGGTGAAA
GTCCCTGTCATCCCTTCAGATTCCAGAGCTGGGATCAGCCATGCCCAGAGGTCTGGTCCTGATGCTGGCAGGGGGGCCCCCTCCTCCATC
CCTGACTGGCTGAGTGGCTTTATCACCACCGAGTGATGTGCTGAGGCCTCCTGCAGTGAATGCTCCTTCCATTCCTGTACTCGGGCAGTG
CCATTCAGCACAGGAGAGCTCTTTTTGCCTTTGGCTTTCAATTCCAAAACATGATTTAATTTCTAACTAAATTAGTATGGCACTAGTTAT
GAAGTATCTGCTTAAAACCCTTCATCATGATATCCTGTGGATTTAAAAACTCTAATTCCATGTTTTCTTCCCATCTGCCTTATATATCTC
ATCACCCTGCTTATCAATATTCAGTTTGATGAGCACTATTAACTAAAATATGAAACTTAAAAACAAAAGCAAGTTGTCCTTAAAAGTTCT
TTTTTTAAGTAAATTGTTGACATACTGCAAATTTTCTATGCAAACTTGCCTCCTGCTGTTATCTGTGAAGCTCAGGAAATCCAAACATTT
GTGTTTCAACAAGGGACAGTAAACTGTGTGTTTACAGCCAAAAGAAATGCCTCATAGTTCTTAACCTCAACTTTTGTAGAAGTATTTTTT
TCTCTGTAATATTTTTATTGGCTCATAAAGATGTTTTCATATCTGAACTCCTAAATAAGTGAAATTACAGTAGATTATATTAACAAAATA
CTTTTTAGGTAGCCATGCTTGAGACTTTTTAAAAATATAACTTTTTCCTTAAAGTTTTCAGCTATAGCAAAAGGTAGTTATGTATGCCAG
ACCTAATATGAGCTGCCACCAACACCCCTAGAACTTTCAGCCATGGTGTCTTCAGAATTGTAGCGCATTTCTGAATCTAGCAAATCCTCC
TTTTACCCGTTGAATGTTTTGAATGCCCTGACTCTACCAGCGCCCATAAATGATCTCTAGAAGGACTGTTAGTACCAATCTGTTTTTCAA
CTTTGAAGCTAAAAACCCTGATATGGTAATATTATGGTGCATAGCAGAGGTCTCGGAAAAAAAATATTTCTGTTCACTTTACTTTCAGGT
TAAAAATGTTTCTAACACGCTTGCAACTTCCCTTATGGCATTAATCTTGTTGAGGGAGAGAGACAGAATCCTGGACTCTCCAAAGTATTT
AACTGAAAGTAGGGCCTGCTCTGACAGGGCCCATGTCCCACAAGGCTGCTTGGCCTCAGTGGGTGCTTGGCTGTGCTGGATGATATGTTG
ATCTGTATTGGATAAGGACCAATGACAGCAAAGCAAAAATGGCTTTAAAGCTTGGTGTTACTTTTCTTAAGTTGTTTAATTATAGTTAAG
CAATTTCAAAAATGCTCCAAAGAAATGTGAAAGGACCTTTTGTCACAGCACTTCAGAAAATACACAACAGCCCCTTCTGCCCCCGCACAG
AAATGCTGCAGAGTATATAAAACTTGAGACATTTTTGTAGGATGCCTGACGAGGTGTAGCCTTTTATCTTGTTTCCGGATGCATATTTAT
TACGAGTACTCTGGTTAAATATTGAAAAGTTATATGCTGTAGTTTTTAGTATTTTGTCTTTGTAATTTACAGAAGTTATTGGAGAAAATA
AACTTGTTTCATTTTGC

>2045_2045_2_ADAMTS12-RAI14_ADAMTS12_chr5_33881224_ENST00000352040_RAI14_chr5_34757573_ENST00000428746_length(amino acids)=1131AA_BP=163
MPCAQRSWLANLSVVAQLLNFGALCYGRQPQPGPVRFPDRRQEHFIKGLPEYHVVGPVRVDASGHFLSYGLHYPITSSRRKRDLDGSEDW
VYYRISHEEKDLFFNLTVNQGFLSNSYIMEKRYGNLSHVKMMASSAPLCHLSGTVLQQGTRVGTAALSACHGLTNEWNKNDDRLLQAVEN
GDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSG
KTALHYAAAQGCLQAVQILCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEALIKKGA
DLNLVDSLGYNALHYSKLSENAGIQSLLLSKISQDADLKTPTKPKQHDQVSKISSERSGTPKKRKAPPPPISPTQLSDVSSPRSITSTPL
SGKESVFFAEPPFKAEISSIRENKDRLSDSTTGADSLLDISSEADQQDLLSLLQAKVASLTLHNKELQDKLQAKSPKEAEADLSFDSYHS
TQTDLGPSLGKPGETSPPDSKSSPSVLIHSLGKSTTDNDVRIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNNTEISENSS
DLSQKLKETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNYSHFHELRVTEEEINVLKQDLQNALEESERNKEKVRELEEKLVEREKGTVI
KPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAEL
EDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEE
KISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIRSEVSQVKREKENIQ
TLLKSKEQEVNELLQKFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQ
NQLAECKKQHQEVISVYRMHLLYAVQGQMDEDVQKVLKQILTMCKNQSQKK

--------------------------------------------------------------
>2045_2045_3_ADAMTS12-RAI14_ADAMTS12_chr5_33881224_ENST00000352040_RAI14_chr5_34757573_ENST00000503673_length(transcript)=3521nt_BP=574nt
TCCTGCTGGGCCACAGGCGAGCGCTTTATTTCTGGAGCTGAGGGCTAAAACTTTTTTGACTTTTCTTCTCCTCAACATCTGAATCATGCC
ATGTGCCCAGAGGAGCTGGCTTGCAAACCTTTCCGTGGTGGCTCAGCTCCTTAACTTTGGGGCGCTTTGCTATGGGAGACAGCCTCAGCC
AGGCCCGGTTCGCTTCCCGGACAGGAGGCAAGAGCATTTTATCAAGGGCCTGCCAGAATACCACGTGGTGGGTCCAGTCCGAGTAGATGC
CAGTGGGCATTTTTTGTCATATGGCTTGCACTATCCCATCACGAGCAGCAGGAGGAAGAGAGATTTGGATGGCTCAGAGGACTGGGTGTA
CTACAGAATTTCTCACGAGGAGAAGGACCTGTTTTTTAACTTGACGGTCAATCAAGGATTTCTTTCCAATAGCTACATCATGGAGAAGAG
ATATGGGAACCTCTCCCATGTTAAGATGATGGCTTCCTCTGCCCCCCTCTGCCATCTCAGTGGCACGGTTCTACAGCAGGGCACCAGAGT
TGGGACGGCAGCCCTCAGTGCCTGCCATGGACTGACCAATGAGTGGAACAAGAATGATGACCGGCTACTGCAGGCCGTGGAGAATGGAGA
TGCGGAGAAGGTGGCCTCACTGCTCGGCAAGAAGGGGGCCAGTGCCACCAAACACGACAGTGAGGGCAAGACCGCTTTCCATCTTGCTGC
TGCAAAAGGACACGTGGAATGCCTCAGGGTCATGATTACACATGGTGTGGATGTGACAGCCCAAGATACTACCGGACACAGCGCCTTACA
TCTCGCAGCCAAGAACAGCCACCATGAATGCATCAGGAAGCTGCTTCAGTCTAAATGCCCAGCCGAAAGTGTCGACAGCTCTGGGAAAAC
AGCTTTACATTATGCAGCGGCTCAGGGCTGCCTTCAAGCTGTGCAGATTCTCTGCGAACACAAGAGCCCCATAAACCTCAAAGATTTGGA
TGGGAATATACCGCTGCTTCTTGCTGTACAAAATGGTCACAGTGAGATCTGTCACTTTCTCCTGGATCATGGAGCAGATGTCAATTCCAG
GAACAAAAGTGGAAGAACTGCTCTCATGCTGGCCTGTGAGATTGGCAGCTCTAACGCTGTGGAAGCCTTAATTAAAAAGGGTGCAGACCT
AAACCTTGTAGATTCTCTTGGATACAATGCCTTACATTATTCCAAACTCTCAGAAAATGCAGGAATTCAAAGCCTTCTATTATCAAAAAT
CTCTCAGGATGCTGATTTAAAGACCCCAACAAAACCAAAGCAGCATGACCAAGTCTCTAAAATAAGCTCAGAAAGAAGTGGAACTCCAAA
AAAACGCAAAGCTCCACCACCTCCTATCAGTCCTACCCAGTTGAGTGATGTCTCTTCCCCAAGATCAATAACTTCGACTCCACTATCGGG
AAAGGAATCGGTATTTTTTGCTGAACCACCCTTCAAGGCTGAGATCAGTTCTATACGAGAAAACAAAGACAGACTAAGTGACAGTACTAC
AGGTGCTGATAGCTTATTGGATATAAGTTCTGAAGCTGACCAACAAGATCTTCTCTCTCTATTGCAAGCAAAAGTTGCTTCCCTTACCTT
ACACAATAAGGAGTTACAAGATAAATTACAGGCCAAATCACCCAAGGAGGCGGAAGCAGACCTAAGCTTTGACTCATACCATTCCACCCA
AACTGACTTGGGCCCATCCCTGGGAAAACCTGGTGAAACCTCTCCCCCAGACTCCAAATCATCTCCATCTGTCTTAATACATTCTTTAGG
TAAATCCACTACTGACAATGATGTCAGAATTCAGCAACTGCAAGAGATTTTGCAAGATCTACAGAAGAGATTAGAGAGCTCTGAAGCAGA
GAGAAAACAGCTACAGGTCGAACTCCAATCCCGAAGGGCAGAACTGGTATGCTTAAACAACACTGAGATTTCAGAGAACAGCTCTGACCT
CAGCCAGAAACTTAAAGAAACTCAGAGCAAATACGAGGAGGCTATGAAAGAAGTCCTTAGTGTGCAGAAGCAGATGAAACTCGGTCTTGT
CTCACCTGAAAGCATGGATAATTATTCACATTTCCACGAGCTGAGGGTCACGGAAGAGGAAATAAATGTGCTAAAGCAGGATCTGCAGAA
TGCATTAGAAGAAAGTGAAAGAAATAAAGAGAAAGTGAGAGAGTTAGAGGAAAAACTGGTAGAGAGGGAGAAAGGTACAGTGATTAAGCC
ACCTGTGGAAGAGTACGAGGAAATGAAAAGTTCATATTGCTCTGTTATTGAGAATATGAATAAGGAGAAAGCATTTTTGTTTGAGAAATA
CCAAGAAGCCCAAGAAGAAATCATGAAATTAAAAGACACACTAAAAAGTCAGATGACACAGGAAGCCAGTGATGAAGCTGAGGACATGAA
AGAAGCCATGAATAGGATGATAGATGAACTCAATAAACAGGTGAGCGAGCTGTCACAGCTGTACAAAGAAGCCCAGGCTGAGCTGGAGGA
TTACAGGAAGAGGAAATCTCTAGAGGATGTCACAGCTGAATATATCCATAAAGCAGAGCATGAGAAACTGATGCAATTGACAAACGTGTC
CAGGGCTAAAGCAGAAGATGCACTGTCTGAAATGAAGTCTCAGTATTCAAAAGTGTTGAATGAGTTGACCCAGCTCAAACAACTGGTGGA
TGCACAAAAAGAGAACTCTGTCTCTATCACAGAACATTTGCAAGTGATAACCACGCTGCGGACTGCAGCAAAAGAGATGGAAGAAAAAAT
AAGCAATCTTAAGGAACACCTTGCAAGCAAGGAAGTGGAAGTAGCAAAGCTGGAGAAACAACTCTTAGAAGAGAAAGCTGCTATGACTGA
TGCAATGGTACCTCGGTCTTCCTATGAAAAACTCCAGTCATCCTTAGAGAGTGAAGTGAGTGTGTTGGCATCGAAATTAAAGGAATCTGT
GAAAGAGAAAGAGAAGGTCCATTCAGAGGTTGTCCAGATTAGAAGTGAGGTCTCACAGGTGAAAAGAGAAAAGGAAAATATTCAGACTCT
CTTGAAATCCAAAGAGCAAGAAGTAAATGAACTTCTGCAAAAATTCCAGCAAGCTCAGGAAGAACTTGCAGAAATGAAAAGATACGCTGA
GAGCTCTTCAAAACTGGAGGAAGATAAAGATAAAAAGATAAATGAGATGTCGAAGGAAGTCACCAAATTGAAGGAGGCCTTGAACAGCCT
CTCCCAGCTCTCCTACTCAACAAGCTCATCCAAAAGGCAGAGTCAGCAGCTGGAGGCGCTGCAGCAGCAAGTCAAACAGCTCCAGAACCA
GCTGGCGGAATGCAAGAAACAACACCAGGAGGTCATATCAGTTTACAGAATGCATCTTCTGTATGCTGTGCAGGGCCAGATGGATGAAGA
TGTCCAGAAAGTACTGAAGCAAATCCTTACCATGTGTAAAAACCAGTCTCAAAAGAAGTAAAGTGGATTCCTTGGCAGGACACTGCCCCT
TGTCATCTGTC

>2045_2045_3_ADAMTS12-RAI14_ADAMTS12_chr5_33881224_ENST00000352040_RAI14_chr5_34757573_ENST00000503673_length(amino acids)=1131AA_BP=163
MPCAQRSWLANLSVVAQLLNFGALCYGRQPQPGPVRFPDRRQEHFIKGLPEYHVVGPVRVDASGHFLSYGLHYPITSSRRKRDLDGSEDW
VYYRISHEEKDLFFNLTVNQGFLSNSYIMEKRYGNLSHVKMMASSAPLCHLSGTVLQQGTRVGTAALSACHGLTNEWNKNDDRLLQAVEN
GDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSG
KTALHYAAAQGCLQAVQILCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEALIKKGA
DLNLVDSLGYNALHYSKLSENAGIQSLLLSKISQDADLKTPTKPKQHDQVSKISSERSGTPKKRKAPPPPISPTQLSDVSSPRSITSTPL
SGKESVFFAEPPFKAEISSIRENKDRLSDSTTGADSLLDISSEADQQDLLSLLQAKVASLTLHNKELQDKLQAKSPKEAEADLSFDSYHS
TQTDLGPSLGKPGETSPPDSKSSPSVLIHSLGKSTTDNDVRIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNNTEISENSS
DLSQKLKETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNYSHFHELRVTEEEINVLKQDLQNALEESERNKEKVRELEEKLVEREKGTVI
KPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAEL
EDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEE
KISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIRSEVSQVKREKENIQ
TLLKSKEQEVNELLQKFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQ
NQLAECKKQHQEVISVYRMHLLYAVQGQMDEDVQKVLKQILTMCKNQSQKK

--------------------------------------------------------------
>2045_2045_4_ADAMTS12-RAI14_ADAMTS12_chr5_33881224_ENST00000352040_RAI14_chr5_34757573_ENST00000506376_length(transcript)=3501nt_BP=574nt
TCCTGCTGGGCCACAGGCGAGCGCTTTATTTCTGGAGCTGAGGGCTAAAACTTTTTTGACTTTTCTTCTCCTCAACATCTGAATCATGCC
ATGTGCCCAGAGGAGCTGGCTTGCAAACCTTTCCGTGGTGGCTCAGCTCCTTAACTTTGGGGCGCTTTGCTATGGGAGACAGCCTCAGCC
AGGCCCGGTTCGCTTCCCGGACAGGAGGCAAGAGCATTTTATCAAGGGCCTGCCAGAATACCACGTGGTGGGTCCAGTCCGAGTAGATGC
CAGTGGGCATTTTTTGTCATATGGCTTGCACTATCCCATCACGAGCAGCAGGAGGAAGAGAGATTTGGATGGCTCAGAGGACTGGGTGTA
CTACAGAATTTCTCACGAGGAGAAGGACCTGTTTTTTAACTTGACGGTCAATCAAGGATTTCTTTCCAATAGCTACATCATGGAGAAGAG
ATATGGGAACCTCTCCCATGTTAAGATGATGGCTTCCTCTGCCCCCCTCTGCCATCTCAGTGGCACGGTTCTACAGCAGGGCACCAGAGT
TGGGACGGCAGCCCTCAGTGCCTGCCATGGACTGACCAATGAGTGGAACAAGAATGATGACCGGCTACTGCAGGCCGTGGAGAATGGAGA
TGCGGAGAAGGTGGCCTCACTGCTCGGCAAGAAGGGGGCCAGTGCCACCAAACACGACAGTGAGGGCAAGACCGCTTTCCATCTTGCTGC
TGCAAAAGGACACGTGGAATGCCTCAGGGTCATGATTACACATGGTGTGGATGTGACAGCCCAAGATACTACCGGACACAGCGCCTTACA
TCTCGCAGCCAAGAACAGCCACCATGAATGCATCAGGAAGCTGCTTCAGTCTAAATGCCCAGCCGAAAGTGTCGACAGCTCTGGGAAAAC
AGCTTTACATTATGCAGCGGCTCAGGGCTGCCTTCAAGCTGTGCAGATTCTCTGCGAACACAAGAGCCCCATAAACCTCAAAGATTTGGA
TGGGAATATACCGCTGCTTCTTGCTGTACAAAATGGTCACAGTGAGATCTGTCACTTTCTCCTGGATCATGGAGCAGATGTCAATTCCAG
GAACAAAAGTGGAAGAACTGCTCTCATGCTGGCCTGTGAGATTGGCAGCTCTAACGCTGTGGAAGCCTTAATTAAAAAGGGTGCAGACCT
AAACCTTGTAGATTCTCTTGGATACAATGCCTTACATTATTCCAAACTCTCAGAAAATGCAGGAATTCAAAGCCTTCTATTATCAAAAAT
CTCTCAGGATGCTGATTTAAAGACCCCAACAAAACCAAAGCAGCATGACCAAGTCTCTAAAATAAGCTCAGAAAGAAGTGGAACTCCAAA
AAAACGCAAAGCTCCACCACCTCCTATCAGTCCTACCCAGTTGAGTGATGTCTCTTCCCCAAGATCAATAACTTCGACTCCACTATCGGG
AAAGGAATCGGTATTTTTTGCTGAACCACCCTTCAAGGCTGAGATCAGTTCTATACGAGAAAACAAAGACAGACTAAGTGACAGTACTAC
AGGTGCTGATAGCTTATTGGATATAAGTTCTGAAGCTGACCAACAAGATCTTCTCTCTCTATTGCAAGCAAAAGTTGCTTCCCTTACCTT
ACACAATAAGGAGTTACAAGATAAATTACAGGCCAAATCACCCAAGGAGGCGGAAGCAGACCTAAGCTTTGACTCATACCATTCCACCCA
AACTGACTTGGGCCCATCCCTGGGAAAACCTGGTGAAACCTCTCCCCCAGACTCCAAATCATCTCCATCTGTCTTAATACATTCTTTAGG
TAAATCCACTACTGACAATGATGTCAGAATTCAGCAACTGCAAGAGATTTTGCAAGATCTACAGAAGAGATTAGAGAGCTCTGAAGCAGA
GAGAAAACAGCTACAGGTCGAACTCCAATCCCGAAGGGCAGAACTGGTATGCTTAAACAACACTGAGATTTCAGAGAACAGCTCTGACCT
CAGCCAGAAACTTAAAGAAACTCAGAGCAAATACGAGGAGGCTATGAAAGAAGTCCTTAGTGTGCAGAAGCAGATGAAACTCGGTCTTGT
CTCACCTGAAAGCATGGATAATTATTCACATTTCCACGAGCTGAGGGTCACGGAAGAGGAAATAAATGTGCTAAAGCAGGATCTGCAGAA
TGCATTAGAAGAAAGTGAAAGAAATAAAGAGAAAGTGAGAGAGTTAGAGGAAAAACTGGTAGAGAGGGAGAAAGGTACAGTGATTAAGCC
ACCTGTGGAAGAGTACGAGGAAATGAAAAGTTCATATTGCTCTGTTATTGAGAATATGAATAAGGAGAAAGCATTTTTGTTTGAGAAATA
CCAAGAAGCCCAAGAAGAAATCATGAAATTAAAAGACACACTAAAAAGTCAGATGACACAGGAAGCCAGTGATGAAGCTGAGGACATGAA
AGAAGCCATGAATAGGATGATAGATGAACTCAATAAACAGGTGAGCGAGCTGTCACAGCTGTACAAAGAAGCCCAGGCTGAGCTGGAGGA
TTACAGGAAGAGGAAATCTCTAGAGGATGTCACAGCTGAATATATCCATAAAGCAGAGCATGAGAAACTGATGCAATTGACAAACGTGTC
CAGGGCTAAAGCAGAAGATGCACTGTCTGAAATGAAGTCTCAGTATTCAAAAGTGTTGAATGAGTTGACCCAGCTCAAACAACTGGTGGA
TGCACAAAAAGAGAACTCTGTCTCTATCACAGAACATTTGCAAGTGATAACCACGCTGCGGACTGCAGCAAAAGAGATGGAAGAAAAAAT
AAGCAATCTTAAGGAACACCTTGCAAGCAAGGAAGTGGAAGTAGCAAAGCTGGAGAAACAACTCTTAGAAGAGAAAGCTGCTATGACTGA
TGCAATGGTACCTCGGTCTTCCTATGAAAAACTCCAGTCATCCTTAGAGAGTGAAGTGAGTGTGTTGGCATCGAAATTAAAGGAATCTGT
GAAAGAGAAAGAGAAGGTCCATTCAGAGGTTGTCCAGATTAGAAGTGAGGTCTCACAGGTGAAAAGAGAAAAGGAAAATATTCAGACTCT
CTTGAAATCCAAAGAGCAAGAAGTAAATGAACTTCTGCAAAAATTCCAGCAAGCTCAGGAAGAACTTGCAGAAATGAAAAGATACGCTGA
GAGCTCTTCAAAACTGGAGGAAGATAAAGATAAAAAGATAAATGAGATGTCGAAGGAAGTCACCAAATTGAAGGAGGCCTTGAACAGCCT
CTCCCAGCTCTCCTACTCAACAAGCTCATCCAAAAGGCAGAGTCAGCAGCTGGAGGCGCTGCAGCAGCAAGTCAAACAGCTCCAGAACCA
GCTGGCGGAATGCAAGAAACAACACCAGGAGGTCATATCAGTTTACAGAATGCATCTTCTGTATGCTGTGCAGGGCCAGATGGATGAAGA
TGTCCAGAAAGTACTGAAGCAAATCCTTACCATGTGTAAAAACCAGTCTCAAAAGAAGTAAAGTGGATTCCTTGGCAGGAC

>2045_2045_4_ADAMTS12-RAI14_ADAMTS12_chr5_33881224_ENST00000352040_RAI14_chr5_34757573_ENST00000506376_length(amino acids)=1131AA_BP=163
MPCAQRSWLANLSVVAQLLNFGALCYGRQPQPGPVRFPDRRQEHFIKGLPEYHVVGPVRVDASGHFLSYGLHYPITSSRRKRDLDGSEDW
VYYRISHEEKDLFFNLTVNQGFLSNSYIMEKRYGNLSHVKMMASSAPLCHLSGTVLQQGTRVGTAALSACHGLTNEWNKNDDRLLQAVEN
GDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSG
KTALHYAAAQGCLQAVQILCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEALIKKGA
DLNLVDSLGYNALHYSKLSENAGIQSLLLSKISQDADLKTPTKPKQHDQVSKISSERSGTPKKRKAPPPPISPTQLSDVSSPRSITSTPL
SGKESVFFAEPPFKAEISSIRENKDRLSDSTTGADSLLDISSEADQQDLLSLLQAKVASLTLHNKELQDKLQAKSPKEAEADLSFDSYHS
TQTDLGPSLGKPGETSPPDSKSSPSVLIHSLGKSTTDNDVRIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNNTEISENSS
DLSQKLKETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNYSHFHELRVTEEEINVLKQDLQNALEESERNKEKVRELEEKLVEREKGTVI
KPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAEL
EDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEE
KISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIRSEVSQVKREKENIQ
TLLKSKEQEVNELLQKFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQ
NQLAECKKQHQEVISVYRMHLLYAVQGQMDEDVQKVLKQILTMCKNQSQKK

--------------------------------------------------------------
>2045_2045_5_ADAMTS12-RAI14_ADAMTS12_chr5_33881224_ENST00000352040_RAI14_chr5_34757573_ENST00000512629_length(transcript)=3394nt_BP=574nt
TCCTGCTGGGCCACAGGCGAGCGCTTTATTTCTGGAGCTGAGGGCTAAAACTTTTTTGACTTTTCTTCTCCTCAACATCTGAATCATGCC
ATGTGCCCAGAGGAGCTGGCTTGCAAACCTTTCCGTGGTGGCTCAGCTCCTTAACTTTGGGGCGCTTTGCTATGGGAGACAGCCTCAGCC
AGGCCCGGTTCGCTTCCCGGACAGGAGGCAAGAGCATTTTATCAAGGGCCTGCCAGAATACCACGTGGTGGGTCCAGTCCGAGTAGATGC
CAGTGGGCATTTTTTGTCATATGGCTTGCACTATCCCATCACGAGCAGCAGGAGGAAGAGAGATTTGGATGGCTCAGAGGACTGGGTGTA
CTACAGAATTTCTCACGAGGAGAAGGACCTGTTTTTTAACTTGACGGTCAATCAAGGATTTCTTTCCAATAGCTACATCATGGAGAAGAG
ATATGGGAACCTCTCCCATGTTAAGATGATGGCTTCCTCTGCCCCCCTCTGCCATCTCAGTGGCACGGTTCTACAGCAGGGCACCAGAGT
TGGGACGGCAGCCCTCAGTGCCTGCCATGGACTGACCAATGAGTGGAACAAGAATGATGACCGGCTACTGCAGGCCGTGGAGAATGGAGA
TGCGGAGAAGGTGGCCTCACTGCTCGGCAAGAAGGGGGCCAGTGCCACCAAACACGACAGTGAGGGCAAGACCGCTTTCCATCTTGCTGC
TGCAAAAGGACACGTGGAATGCCTCAGGGTCATGATTACACATGGTGTGGATGTGACAGCCCAAGATACTACCGGACACAGCGCCTTACA
TCTCGCAGCCAAGAACAGCCACCATGAATGCATCAGGAAGCTGCTTCAGTCTAAATGCCCAGCCGAAAGTGTCGACAGCTCTGGGAAAAC
AGCTTTACATTATGCAGCGGCTCAGGGCTGCCTTCAAGCTGTGCAGATTCTCTGCGAACACAAGAGCCCCATAAACCTCAAAGATTTGGA
TGGGAATATACCGCTGCTTCTTGCTGTACAAAATGGTCACAGTGAGATCTGTCACTTTCTCCTGGATCATGGAGCAGATGTCAATTCCAG
GAACAAAAGTGGAAGAACTGCTCTCATGCTGGCCTGTGAGATTGGCAGCTCTAACGCTGTGGAAGCCTTAATTAAAAAGGGTGCAGACCT
AAACCTTGTAGATTCTCTTGGATACAATGCCTTACATTATTCCAAACTCTCAGAAAATGCAGGAATTCAAAGCCTTCTATTATCAAAAAT
CTCTCAGGATGCTGATTTAAAGACCCCAACAAAACCAAAGCAGTTGAGTGATGTCTCTTCCCCAAGATCAATAACTTCGACTCCACTATC
GGGAAAGGAATCGGTATTTTTTGCTGAACCACCCTTCAAGGCTGAGATCAGTTCTATACGAGAAAACAAAGACAGACTAAGTGACAGTAC
TACAGGTGCTGATAGCTTATTGGATATAAGTTCTGAAGCTGACCAACAAGATCTTCTCTCTCTATTGCAAGCAAAAGTTGCTTCCCTTAC
CTTACACAATAAGGAGTTACAAGATAAATTACAGGCCAAATCACCCAAGGAGGCGGAAGCAGACCTAAGCTTTGACTCATACCATTCCAC
CCAAACTGACTTGGGCCCATCCCTGGGAAAACCTGGTGAAACCTCTCCCCCAGACTCCAAATCATCTCCATCTGTCTTAATACATTCTTT
AGGTAAATCCACTACTGACAATGATGTCAGAATTCAGCAACTGCAAGAGATTTTGCAAGATCTACAGAAGAGATTAGAGAGCTCTGAAGC
AGAGAGAAAACAGCTACAGGTCGAACTCCAATCCCGAAGGGCAGAACTGGTATGCTTAAACAACACTGAGATTTCAGAGAACAGCTCTGA
CCTCAGCCAGAAACTTAAAGAAACTCAGAGCAAATACGAGGAGGCTATGAAAGAAGTCCTTAGTGTGCAGAAGCAGATGAAACTCGGTCT
TGTCTCACCTGAAAGCATGGATAATTATTCACATTTCCACGAGCTGAGGGTCACGGAAGAGGAAATAAATGTGCTAAAGCAGGATCTGCA
GAATGCATTAGAAGAAAGTGAAAGAAATAAAGAGAAAGTGAGAGAGTTAGAGGAAAAACTGGTAGAGAGGGAGAAAGGTACAGTGATTAA
GCCACCTGTGGAAGAGTACGAGGAAATGAAAAGTTCATATTGCTCTGTTATTGAGAATATGAATAAGGAGAAAGCATTTTTGTTTGAGAA
ATACCAAGAAGCCCAAGAAGAAATCATGAAATTAAAAGACACACTAAAAAGTCAGATGACACAGGAAGCCAGTGATGAAGCTGAGGACAT
GAAAGAAGCCATGAATAGGATGATAGATGAACTCAATAAACAGGTGAGCGAGCTGTCACAGCTGTACAAAGAAGCCCAGGCTGAGCTGGA
GGATTACAGGAAGAGGAAATCTCTAGAGGATGTCACAGCTGAATATATCCATAAAGCAGAGCATGAGAAACTGATGCAATTGACAAACGT
GTCCAGGGCTAAAGCAGAAGATGCACTGTCTGAAATGAAGTCTCAGTATTCAAAAGTGTTGAATGAGTTGACCCAGCTCAAACAACTGGT
GGATGCACAAAAAGAGAACTCTGTCTCTATCACAGAACATTTGCAAGTGATAACCACGCTGCGGACTGCAGCAAAAGAGATGGAAGAAAA
AATAAGCAATCTTAAGGAACACCTTGCAAGCAAGGAAGTGGAAGTAGCAAAGCTGGAGAAACAACTCTTAGAAGAGAAAGCTGCTATGAC
TGATGCAATGGTACCTCGGTCTTCCTATGAAAAACTCCAGTCATCCTTAGAGAGTGAAGTGAGTGTGTTGGCATCGAAATTAAAGGAATC
TGTGAAAGAGAAAGAGAAGGTCCATTCAGAGGTTGTCCAGATTAGAAGTGAGGTCTCACAGGTGAAAAGAGAAAAGGAAAATATTCAGAC
TCTCTTGAAATCCAAAGAGCAAGAAGTAAATGAACTTCTGCAAAAATTCCAGCAAGCTCAGGAAGAACTTGCAGAAATGAAAAGATACGC
TGAGAGCTCTTCAAAACTGGAGGAAGATAAAGATAAAAAGATAAATGAGATGTCGAAGGAAGTCACCAAATTGAAGGAGGCCTTGAACAG
CCTCTCCCAGCTCTCCTACTCAACAAGCTCATCCAAAAGGCAGAGTCAGCAGCTGGAGGCGCTGCAGCAGCAAGTCAAACAGCTCCAGAA
CCAGCTGGCGGAATGCAAGAAACAACACCAGGAGGTCATATCAGTTTACAGAATGCATCTTCTGTATGCTGTGCAGGGCCAGATGGATGA
AGATGTCCAGAAAGTACTGAAGCAAATCCTTACCATGTGTAAAAACCAGTCTCAAAAGAAGTAA

>2045_2045_5_ADAMTS12-RAI14_ADAMTS12_chr5_33881224_ENST00000352040_RAI14_chr5_34757573_ENST00000512629_length(amino acids)=1103AA_BP=163
MPCAQRSWLANLSVVAQLLNFGALCYGRQPQPGPVRFPDRRQEHFIKGLPEYHVVGPVRVDASGHFLSYGLHYPITSSRRKRDLDGSEDW
VYYRISHEEKDLFFNLTVNQGFLSNSYIMEKRYGNLSHVKMMASSAPLCHLSGTVLQQGTRVGTAALSACHGLTNEWNKNDDRLLQAVEN
GDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSG
KTALHYAAAQGCLQAVQILCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEALIKKGA
DLNLVDSLGYNALHYSKLSENAGIQSLLLSKISQDADLKTPTKPKQLSDVSSPRSITSTPLSGKESVFFAEPPFKAEISSIRENKDRLSD
STTGADSLLDISSEADQQDLLSLLQAKVASLTLHNKELQDKLQAKSPKEAEADLSFDSYHSTQTDLGPSLGKPGETSPPDSKSSPSVLIH
SLGKSTTDNDVRIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNNTEISENSSDLSQKLKETQSKYEEAMKEVLSVQKQMKL
GLVSPESMDNYSHFHELRVTEEEINVLKQDLQNALEESERNKEKVRELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLF
EKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSLEDVTAEYIHKAEHEKLMQLT
NVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAA
MTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIRSEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKR
YAESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQNQLAECKKQHQEVISVYRMHLLYAVQGQM
DEDVQKVLKQILTMCKNQSQKKX

--------------------------------------------------------------
>2045_2045_6_ADAMTS12-RAI14_ADAMTS12_chr5_33881224_ENST00000352040_RAI14_chr5_34757573_ENST00000515799_length(transcript)=3523nt_BP=574nt
TCCTGCTGGGCCACAGGCGAGCGCTTTATTTCTGGAGCTGAGGGCTAAAACTTTTTTGACTTTTCTTCTCCTCAACATCTGAATCATGCC
ATGTGCCCAGAGGAGCTGGCTTGCAAACCTTTCCGTGGTGGCTCAGCTCCTTAACTTTGGGGCGCTTTGCTATGGGAGACAGCCTCAGCC
AGGCCCGGTTCGCTTCCCGGACAGGAGGCAAGAGCATTTTATCAAGGGCCTGCCAGAATACCACGTGGTGGGTCCAGTCCGAGTAGATGC
CAGTGGGCATTTTTTGTCATATGGCTTGCACTATCCCATCACGAGCAGCAGGAGGAAGAGAGATTTGGATGGCTCAGAGGACTGGGTGTA
CTACAGAATTTCTCACGAGGAGAAGGACCTGTTTTTTAACTTGACGGTCAATCAAGGATTTCTTTCCAATAGCTACATCATGGAGAAGAG
ATATGGGAACCTCTCCCATGTTAAGATGATGGCTTCCTCTGCCCCCCTCTGCCATCTCAGTGGCACGGTTCTACAGCAGGGCACCAGAGT
TGGGACGGCAGCCCTCAGTGCCTGCCATGGACTGACCAATGAGTGGAACAAGAATGATGACCGGCTACTGCAGGCCGTGGAGAATGGAGA
TGCGGAGAAGGTGGCCTCACTGCTCGGCAAGAAGGGGGCCAGTGCCACCAAACACGACAGTGAGGGCAAGACCGCTTTCCATCTTGCTGC
TGCAAAAGGACACGTGGAATGCCTCAGGGTCATGATTACACATGGTGTGGATGTGACAGCCCAAGATACTACCGGACACAGCGCCTTACA
TCTCGCAGCCAAGAACAGCCACCATGAATGCATCAGGAAGCTGCTTCAGTCTAAATGCCCAGCCGAAAGTGTCGACAGCTCTGGGAAAAC
AGCTTTACATTATGCAGCGGCTCAGGGCTGCCTTCAAGCTGTGCAGATTCTCTGCGAACACAAGAGCCCCATAAACCTCAAAGATTTGGA
TGGGAATATACCGCTGCTTCTTGCTGTACAAAATGGTCACAGTGAGATCTGTCACTTTCTCCTGGATCATGGAGCAGATGTCAATTCCAG
GAACAAAAGTGGAAGAACTGCTCTCATGCTGGCCTGTGAGATTGGCAGCTCTAACGCTGTGGAAGCCTTAATTAAAAAGGGTGCAGACCT
AAACCTTGTAGATTCTCTTGGATACAATGCCTTACATTATTCCAAACTCTCAGAAAATGCAGGAATTCAAAGCCTTCTATTATCAAAAAT
CTCTCAGGATGCTGATTTAAAGACCCCAACAAAACCAAAGCAGCATGACCAAGTCTCTAAAATAAGCTCAGAAAGAAGTGGAACTCCAAA
AAAACGCAAAGCTCCACCACCTCCTATCAGTCCTACCCAGTTGAGTGATGTCTCTTCCCCAAGATCAATAACTTCGACTCCACTATCGGG
AAAGGAATCGGTATTTTTTGCTGAACCACCCTTCAAGGCTGAGATCAGTTCTATACGAGAAAACAAAGACAGACTAAGTGACAGTACTAC
AGGTGCTGATAGCTTATTGGATATAAGTTCTGAAGCTGACCAACAAGATCTTCTCTCTCTATTGCAAGCAAAAGTTGCTTCCCTTACCTT
ACACAATAAGGAGTTACAAGATAAATTACAGGCCAAATCACCCAAGGAGGCGGAAGCAGACCTAAGCTTTGACTCATACCATTCCACCCA
AACTGACTTGGGCCCATCCCTGGGAAAACCTGGTGAAACCTCTCCCCCAGACTCCAAATCATCTCCATCTGTCTTAATACATTCTTTAGG
TAAATCCACTACTGACAATGATGTCAGAATTCAGCAACTGCAAGAGATTTTGCAAGATCTACAGAAGAGATTAGAGAGCTCTGAAGCAGA
GAGAAAACAGCTACAGGTCGAACTCCAATCCCGAAGGGCAGAACTGGTATGCTTAAACAACACTGAGATTTCAGAGAACAGCTCTGACCT
CAGCCAGAAACTTAAAGAAACTCAGAGCAAATACGAGGAGGCTATGAAAGAAGTCCTTAGTGTGCAGAAGCAGATGAAACTCGGTCTTGT
CTCACCTGAAAGCATGGATAATTATTCACATTTCCACGAGCTGAGGGTCACGGAAGAGGAAATAAATGTGCTAAAGCAGGATCTGCAGAA
TGCATTAGAAGAAAGTGAAAGAAATAAAGAGAAAGTGAGAGAGTTAGAGGAAAAACTGGTAGAGAGGGAGAAAGGTACAGTGATTAAGCC
ACCTGTGGAAGAGTACGAGGAAATGAAAAGTTCATATTGCTCTGTTATTGAGAATATGAATAAGGAGAAAGCATTTTTGTTTGAGAAATA
CCAAGAAGCCCAAGAAGAAATCATGAAATTAAAAGACACACTAAAAAGTCAGATGACACAGGAAGCCAGTGATGAAGCTGAGGACATGAA
AGAAGCCATGAATAGGATGATAGATGAACTCAATAAACAGGTGAGCGAGCTGTCACAGCTGTACAAAGAAGCCCAGGCTGAGCTGGAGGA
TTACAGGAAGAGGAAATCTCTAGAGGATGTCACAGCTGAATATATCCATAAAGCAGAGCATGAGAAACTGATGCAATTGACAAACGTGTC
CAGGGCTAAAGCAGAAGATGCACTGTCTGAAATGAAGTCTCAGTATTCAAAAGTGTTGAATGAGTTGACCCAGCTCAAACAACTGGTGGA
TGCACAAAAAGAGAACTCTGTCTCTATCACAGAACATTTGCAAGTGATAACCACGCTGCGGACTGCAGCAAAAGAGATGGAAGAAAAAAT
AAGCAATCTTAAGGAACACCTTGCAAGCAAGGAAGTGGAAGTAGCAAAGCTGGAGAAACAACTCTTAGAAGAGAAAGCTGCTATGACTGA
TGCAATGGTACCTCGGTCTTCCTATGAAAAACTCCAGTCATCCTTAGAGAGTGAAGTGAGTGTGTTGGCATCGAAATTAAAGGAATCTGT
GAAAGAGAAAGAGAAGGTCCATTCAGAGGTTGTCCAGATTAGAAGTGAGGTCTCACAGGTGAAAAGAGAAAAGGAAAATATTCAGACTCT
CTTGAAATCCAAAGAGCAAGAAGTAAATGAACTTCTGCAAAAATTCCAGCAAGCTCAGGAAGAACTTGCAGAAATGAAAAGATACGCTGA
GAGCTCTTCAAAACTGGAGGAAGATAAAGATAAAAAGATAAATGAGATGTCGAAGGAAGTCACCAAATTGAAGGAGGCCTTGAACAGCCT
CTCCCAGCTCTCCTACTCAACAAGCTCATCCAAAAGGCAGAGTCAGCAGCTGGAGGCGCTGCAGCAGCAAGTCAAACAGCTCCAGAACCA
GCTGGCGGAATGCAAGAAACAACACCAGGAGGTCATATCAGTTTACAGAATGCATCTTCTGTATGCTGTGCAGGGCCAGATGGATGAAGA
TGTCCAGAAAGTACTGAAGCAAATCCTTACCATGTGTAAAAACCAGTCTCAAAAGAAGTAAAGTGGATTCCTTGGCAGGACACTGCCCCT
TGTCATCTGTCTT

>2045_2045_6_ADAMTS12-RAI14_ADAMTS12_chr5_33881224_ENST00000352040_RAI14_chr5_34757573_ENST00000515799_length(amino acids)=1131AA_BP=163
MPCAQRSWLANLSVVAQLLNFGALCYGRQPQPGPVRFPDRRQEHFIKGLPEYHVVGPVRVDASGHFLSYGLHYPITSSRRKRDLDGSEDW
VYYRISHEEKDLFFNLTVNQGFLSNSYIMEKRYGNLSHVKMMASSAPLCHLSGTVLQQGTRVGTAALSACHGLTNEWNKNDDRLLQAVEN
GDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSG
KTALHYAAAQGCLQAVQILCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEALIKKGA
DLNLVDSLGYNALHYSKLSENAGIQSLLLSKISQDADLKTPTKPKQHDQVSKISSERSGTPKKRKAPPPPISPTQLSDVSSPRSITSTPL
SGKESVFFAEPPFKAEISSIRENKDRLSDSTTGADSLLDISSEADQQDLLSLLQAKVASLTLHNKELQDKLQAKSPKEAEADLSFDSYHS
TQTDLGPSLGKPGETSPPDSKSSPSVLIHSLGKSTTDNDVRIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNNTEISENSS
DLSQKLKETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNYSHFHELRVTEEEINVLKQDLQNALEESERNKEKVRELEEKLVEREKGTVI
KPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAEL
EDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEE
KISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIRSEVSQVKREKENIQ
TLLKSKEQEVNELLQKFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQ
NQLAECKKQHQEVISVYRMHLLYAVQGQMDEDVQKVLKQILTMCKNQSQKK

--------------------------------------------------------------
>2045_2045_7_ADAMTS12-RAI14_ADAMTS12_chr5_33881224_ENST00000504830_RAI14_chr5_34757573_ENST00000265109_length(transcript)=5594nt_BP=825nt
GAGCGGGCGGGCTGCGAGGCCGCGGGGCATGCGGGAGGCGGAGGGGTGGGGACCGGGGTGGGCTGCGCCCTCCCGCTCTGGCCCATTCCA
CACCCCGCCGAAAGCGGACACTGTCAGCTGAATCACTCCCCTTTTAGGAGGAGGGAGGGGAAAAAGGTGTCTAGCTCCTTTCTGCTTAAA
AAAGCACAGGGAGATCGCGGGCAGCTTTGCAGTCGCTGCCTTCTCGCGCCTGACCATGCACCCCTGCATCTTCCTGCTGGGCCACAGGCG
AGCGCTTTATTTCTGGAGCTGAGGGCTAAAACTTTTTTGACTTTTCTTCTCCTCAACATCTGAATCATGCCATGTGCCCAGAGGAGCTGG
CTTGCAAACCTTTCCGTGGTGGCTCAGCTCCTTAACTTTGGGGCGCTTTGCTATGGGAGACAGCCTCAGCCAGGCCCGGTTCGCTTCCCG
GACAGGAGGCAAGAGCATTTTATCAAGGGCCTGCCAGAATACCACGTGGTGGGTCCAGTCCGAGTAGATGCCAGTGGGCATTTTTTGTCA
TATGGCTTGCACTATCCCATCACGAGCAGCAGGAGGAAGAGAGATTTGGATGGCTCAGAGGACTGGGTGTACTACAGAATTTCTCACGAG
GAGAAGGACCTGTTTTTTAACTTGACGGTCAATCAAGGATTTCTTTCCAATAGCTACATCATGGAGAAGAGATATGGGAACCTCTCCCAT
GTTAAGATGATGGCTTCCTCTGCCCCCCTCTGCCATCTCAGTGGCACGGTTCTACAGCAGGGCACCAGAGTTGGGACGGCAGCCCTCAGT
GCCTGCCATGGACTGACCAATGAGTGGAACAAGAATGATGACCGGCTACTGCAGGCCGTGGAGAATGGAGATGCGGAGAAGGTGGCCTCA
CTGCTCGGCAAGAAGGGGGCCAGTGCCACCAAACACGACAGTGAGGGCAAGACCGCTTTCCATCTTGCTGCTGCAAAAGGACACGTGGAA
TGCCTCAGGGTCATGATTACACATGGTGTGGATGTGACAGCCCAAGATACTACCGGACACAGCGCCTTACATCTCGCAGCCAAGAACAGC
CACCATGAATGCATCAGGAAGCTGCTTCAGTCTAAATGCCCAGCCGAAAGTGTCGACAGCTCTGGGAAAACAGCTTTACATTATGCAGCG
GCTCAGGGCTGCCTTCAAGCTGTGCAGATTCTCTGCGAACACAAGAGCCCCATAAACCTCAAAGATTTGGATGGGAATATACCGCTGCTT
CTTGCTGTACAAAATGGTCACAGTGAGATCTGTCACTTTCTCCTGGATCATGGAGCAGATGTCAATTCCAGGAACAAAAGTGGAAGAACT
GCTCTCATGCTGGCCTGTGAGATTGGCAGCTCTAACGCTGTGGAAGCCTTAATTAAAAAGGGTGCAGACCTAAACCTTGTAGATTCTCTT
GGATACAATGCCTTACATTATTCCAAACTCTCAGAAAATGCAGGAATTCAAAGCCTTCTATTATCAAAAATCTCTCAGGATGCTGATTTA
AAGACCCCAACAAAACCAAAGCAGCATGACCAAGTCTCTAAAATAAGCTCAGAAAGAAGTGGAACTCCAAAAAAACGCAAAGCTCCACCA
CCTCCTATCAGTCCTACCCAGTTGAGTGATGTCTCTTCCCCAAGATCAATAACTTCGACTCCACTATCGGGAAAGGAATCGGTATTTTTT
GCTGAACCACCCTTCAAGGCTGAGATCAGTTCTATACGAGAAAACAAAGACAGACTAAGTGACAGTACTACAGGTGCTGATAGCTTATTG
GATATAAGTTCTGAAGCTGACCAACAAGATCTTCTCTCTCTATTGCAAGCAAAAGTTGCTTCCCTTACCTTACACAATAAGGAGTTACAA
GATAAATTACAGGCCAAATCACCCAAGGAGGCGGAAGCAGACCTAAGCTTTGACTCATACCATTCCACCCAAACTGACTTGGGCCCATCC
CTGGGAAAACCTGGTGAAACCTCTCCCCCAGACTCCAAATCATCTCCATCTGTCTTAATACATTCTTTAGGTAAATCCACTACTGACAAT
GATGTCAGAATTCAGCAACTGCAAGAGATTTTGCAAGATCTACAGAAGAGATTAGAGAGCTCTGAAGCAGAGAGAAAACAGCTACAGGTC
GAACTCCAATCCCGAAGGGCAGAACTGGTATGCTTAAACAACACTGAGATTTCAGAGAACAGCTCTGACCTCAGCCAGAAACTTAAAGAA
ACTCAGAGCAAATACGAGGAGGCTATGAAAGAAGTCCTTAGTGTGCAGAAGCAGATGAAACTCGGTCTTGTCTCACCTGAAAGCATGGAT
AATTATTCACATTTCCACGAGCTGAGGGTCACGGAAGAGGAAATAAATGTGCTAAAGCAGGATCTGCAGAATGCATTAGAAGAAAGTGAA
AGAAATAAAGAGAAAGTGAGAGAGTTAGAGGAAAAACTGGTAGAGAGGGAGAAAGGTACAGTGATTAAGCCACCTGTGGAAGAGTACGAG
GAAATGAAAAGTTCATATTGCTCTGTTATTGAGAATATGAATAAGGAGAAAGCATTTTTGTTTGAGAAATACCAAGAAGCCCAAGAAGAA
ATCATGAAATTAAAAGACACACTAAAAAGTCAGATGACACAGGAAGCCAGTGATGAAGCTGAGGACATGAAAGAAGCCATGAATAGGATG
ATAGATGAACTCAATAAACAGGTGAGCGAGCTGTCACAGCTGTACAAAGAAGCCCAGGCTGAGCTGGAGGATTACAGGAAGAGGAAATCT
CTAGAGGATGTCACAGCTGAATATATCCATAAAGCAGAGCATGAGAAACTGATGCAATTGACAAACGTGTCCAGGGCTAAAGCAGAAGAT
GCACTGTCTGAAATGAAGTCTCAGTATTCAAAAGTGTTGAATGAGTTGACCCAGCTCAAACAACTGGTGGATGCACAAAAAGAGAACTCT
GTCTCTATCACAGAACATTTGCAAGTGATAACCACGCTGCGGACTGCAGCAAAAGAGATGGAAGAAAAAATAAGCAATCTTAAGGAACAC
CTTGCAAGCAAGGAAGTGGAAGTAGCAAAGCTGGAGAAACAACTCTTAGAAGAGAAAGCTGCTATGACTGATGCAATGGTACCTCGGTCT
TCCTATGAAAAACTCCAGTCATCCTTAGAGAGTGAAGTGAGTGTGTTGGCATCGAAATTAAAGGAATCTGTGAAAGAGAAAGAGAAGGTC
CATTCAGAGGTTGTCCAGATTAGAAGTGAGGTCTCACAGGTGAAAAGAGAAAAGGAAAATATTCAGACTCTCTTGAAATCCAAAGAGCAA
GAAGTAAATGAACTTCTGCAAAAATTCCAGCAAGCTCAGGAAGAACTTGCAGAAATGAAAAGATACGCTGAGAGCTCTTCAAAACTGGAG
GAAGATAAAGATAAAAAGATAAATGAGATGTCGAAGGAAGTCACCAAATTGAAGGAGGCCTTGAACAGCCTCTCCCAGCTCTCCTACTCA
ACAAGCTCATCCAAAAGGCAGAGTCAGCAGCTGGAGGCGCTGCAGCAGCAAGTCAAACAGCTCCAGAACCAGCTGGCGGAATGCAAGAAA
CAACACCAGGAGGTCATATCAGTTTACAGAATGCATCTTCTGTATGCTGTGCAGGGCCAGATGGATGAAGATGTCCAGAAAGTACTGAAG
CAAATCCTTACCATGTGTAAAAACCAGTCTCAAAAGAAGTAAAGTGGATTCCTTGGCAGGACACTGCCCCTTGTCATCTGTCTTTGTGTT
AGATCCAGAGTTGTCGGCAGCCGCTGCCATTGTTCTCATTCGTGGTATGCACTGTGGCCTAGCGTAGCTTCTTCCCTTTCCAAAGGTTTC
TGAGGACTTCTCCCAGGAGAAGACTGCCCGCCTCAGAACTGCTTAGAGACTTCAAACCAGCAGAGGTGAAAGTCCCTGTCATCCCTTCAG
ATTCCAGAGCTGGGATCAGCCATGCCCAGAGGTCTGGTCCTGATGCTGGCAGGGGGGCCCCCTCCTCCATCCCTGACTGGCTGAGTGGCT
TTATCACCACCGAGTGATGTGCTGAGGCCTCCTGCAGTGAATGCTCCTTCCATTCCTGTACTCGGGCAGTGCCATTCAGCACAGGAGAGC
TCTTTTTGCCTTTGGCTTTCAATTCCAAAACATGATTTAATTTCTAACTAAATTAGTATGGCACTAGTTATGAAGTATCTGCTTAAAACC
CTTCATCATGATATCCTGTGGATTTAAAAACTCTAATTCCATGTTTTCTTCCCATCTGCCTTATATATCTCATCACCCTGCTTATCAATA
TTCAGTTTGATGAGCACTATTAACTAAAATATGAAACTTAAAAACAAAAGCAAGTTGTCCTTAAAAGTTCTTTTTTTAAGTAAATTGTTG
ACATACTGCAAATTTTCTATGCAAACTTGCCTCCTGCTGTTATCTGTGAAGCTCAGGAAATCCAAACATTTGTGTTTCAACAAGGGACAG
TAAACTGTGTGTTTACAGCCAAAAGAAATGCCTCATAGTTCTTAACCTCAACTTTTGTAGAAGTATTTTTTTCTCTGTAATATTTTTATT
GGCTCATAAAGATGTTTTCATATCTGAACTCCTAAATAAGTGAAATTACAGTAGATTATATTAACAAAATACTTTTTAGGTAGCCATGCT
TGAGACTTTTTAAAAATATAACTTTTTCCTTAAAGTTTTCAGCTATAGCAAAAGGTAGTTATGTATGCCAGACCTAATATGAGCTGCCAC
CAACACCCCTAGAACTTTCAGCCATGGTGTCTTCAGAATTGTAGCGCATTTCTGAATCTAGCAAATCCTCCTTTTACCCGTTGAATGTTT
TGAATGCCCTGACTCTACCAGCGCCCATAAATGATCTCTAGAAGGACTGTTAGTACCAATCTGTTTTTCAACTTTGAAGCTAAAAACCCT
GATATGGTAATATTATGGTGCATAGCAGAGGTCTCGGAAAAAAAATATTTCTGTTCACTTTACTTTCAGGTTAAAAATGTTTCTAACACG
CTTGCAACTTCCCTTATGGCATTAATCTTGTTGAGGGAGAGAGACAGAATCCTGGACTCTCCAAAGTATTTAACTGAAAGTAGGGCCTGC
TCTGACAGGGCCCATGTCCCACAAGGCTGCTTGGCCTCAGTGGGTGCTTGGCTGTGCTGGATGATATGTTGATCTGTATTGGATAAGGAC
CAATGACAGCAAAGCAAAAATGGCTTTAAAGCTTGGTGTTACTTTTCTTAAGTTGTTTAATTATAGTTAAGCAATTTCAAAAATGCTCCA
AAGAAATGTGAAAGGACCTTTTGTCACAGCACTTCAGAAAATACACAACAGCCCCTTCTGCCCCCGCACAGAAATGCTGCAGAGTATATA
AAACTTGAGACATTTTTGTAGGATGCCTGACGAGGTGTAGCCTTTTATCTTGTTTCCGGATGCATATTTATTACGAGTACTCTGGTTAAA
TATTGAAAAGTTATATGCTGTAGTTTTTAGTATTTTGTCTTTGTAATTTACAGAAGTTATTGGAGAAAATAAACTTGTTTCATTTTGCAT
TTCTGGTGTTGATT

>2045_2045_7_ADAMTS12-RAI14_ADAMTS12_chr5_33881224_ENST00000504830_RAI14_chr5_34757573_ENST00000265109_length(amino acids)=1131AA_BP=163
MPCAQRSWLANLSVVAQLLNFGALCYGRQPQPGPVRFPDRRQEHFIKGLPEYHVVGPVRVDASGHFLSYGLHYPITSSRRKRDLDGSEDW
VYYRISHEEKDLFFNLTVNQGFLSNSYIMEKRYGNLSHVKMMASSAPLCHLSGTVLQQGTRVGTAALSACHGLTNEWNKNDDRLLQAVEN
GDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSG
KTALHYAAAQGCLQAVQILCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEALIKKGA
DLNLVDSLGYNALHYSKLSENAGIQSLLLSKISQDADLKTPTKPKQHDQVSKISSERSGTPKKRKAPPPPISPTQLSDVSSPRSITSTPL
SGKESVFFAEPPFKAEISSIRENKDRLSDSTTGADSLLDISSEADQQDLLSLLQAKVASLTLHNKELQDKLQAKSPKEAEADLSFDSYHS
TQTDLGPSLGKPGETSPPDSKSSPSVLIHSLGKSTTDNDVRIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNNTEISENSS
DLSQKLKETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNYSHFHELRVTEEEINVLKQDLQNALEESERNKEKVRELEEKLVEREKGTVI
KPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAEL
EDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEE
KISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIRSEVSQVKREKENIQ
TLLKSKEQEVNELLQKFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQ
NQLAECKKQHQEVISVYRMHLLYAVQGQMDEDVQKVLKQILTMCKNQSQKK

--------------------------------------------------------------
>2045_2045_8_ADAMTS12-RAI14_ADAMTS12_chr5_33881224_ENST00000504830_RAI14_chr5_34757573_ENST00000428746_length(transcript)=5578nt_BP=825nt
GAGCGGGCGGGCTGCGAGGCCGCGGGGCATGCGGGAGGCGGAGGGGTGGGGACCGGGGTGGGCTGCGCCCTCCCGCTCTGGCCCATTCCA
CACCCCGCCGAAAGCGGACACTGTCAGCTGAATCACTCCCCTTTTAGGAGGAGGGAGGGGAAAAAGGTGTCTAGCTCCTTTCTGCTTAAA
AAAGCACAGGGAGATCGCGGGCAGCTTTGCAGTCGCTGCCTTCTCGCGCCTGACCATGCACCCCTGCATCTTCCTGCTGGGCCACAGGCG
AGCGCTTTATTTCTGGAGCTGAGGGCTAAAACTTTTTTGACTTTTCTTCTCCTCAACATCTGAATCATGCCATGTGCCCAGAGGAGCTGG
CTTGCAAACCTTTCCGTGGTGGCTCAGCTCCTTAACTTTGGGGCGCTTTGCTATGGGAGACAGCCTCAGCCAGGCCCGGTTCGCTTCCCG
GACAGGAGGCAAGAGCATTTTATCAAGGGCCTGCCAGAATACCACGTGGTGGGTCCAGTCCGAGTAGATGCCAGTGGGCATTTTTTGTCA
TATGGCTTGCACTATCCCATCACGAGCAGCAGGAGGAAGAGAGATTTGGATGGCTCAGAGGACTGGGTGTACTACAGAATTTCTCACGAG
GAGAAGGACCTGTTTTTTAACTTGACGGTCAATCAAGGATTTCTTTCCAATAGCTACATCATGGAGAAGAGATATGGGAACCTCTCCCAT
GTTAAGATGATGGCTTCCTCTGCCCCCCTCTGCCATCTCAGTGGCACGGTTCTACAGCAGGGCACCAGAGTTGGGACGGCAGCCCTCAGT
GCCTGCCATGGACTGACCAATGAGTGGAACAAGAATGATGACCGGCTACTGCAGGCCGTGGAGAATGGAGATGCGGAGAAGGTGGCCTCA
CTGCTCGGCAAGAAGGGGGCCAGTGCCACCAAACACGACAGTGAGGGCAAGACCGCTTTCCATCTTGCTGCTGCAAAAGGACACGTGGAA
TGCCTCAGGGTCATGATTACACATGGTGTGGATGTGACAGCCCAAGATACTACCGGACACAGCGCCTTACATCTCGCAGCCAAGAACAGC
CACCATGAATGCATCAGGAAGCTGCTTCAGTCTAAATGCCCAGCCGAAAGTGTCGACAGCTCTGGGAAAACAGCTTTACATTATGCAGCG
GCTCAGGGCTGCCTTCAAGCTGTGCAGATTCTCTGCGAACACAAGAGCCCCATAAACCTCAAAGATTTGGATGGGAATATACCGCTGCTT
CTTGCTGTACAAAATGGTCACAGTGAGATCTGTCACTTTCTCCTGGATCATGGAGCAGATGTCAATTCCAGGAACAAAAGTGGAAGAACT
GCTCTCATGCTGGCCTGTGAGATTGGCAGCTCTAACGCTGTGGAAGCCTTAATTAAAAAGGGTGCAGACCTAAACCTTGTAGATTCTCTT
GGATACAATGCCTTACATTATTCCAAACTCTCAGAAAATGCAGGAATTCAAAGCCTTCTATTATCAAAAATCTCTCAGGATGCTGATTTA
AAGACCCCAACAAAACCAAAGCAGCATGACCAAGTCTCTAAAATAAGCTCAGAAAGAAGTGGAACTCCAAAAAAACGCAAAGCTCCACCA
CCTCCTATCAGTCCTACCCAGTTGAGTGATGTCTCTTCCCCAAGATCAATAACTTCGACTCCACTATCGGGAAAGGAATCGGTATTTTTT
GCTGAACCACCCTTCAAGGCTGAGATCAGTTCTATACGAGAAAACAAAGACAGACTAAGTGACAGTACTACAGGTGCTGATAGCTTATTG
GATATAAGTTCTGAAGCTGACCAACAAGATCTTCTCTCTCTATTGCAAGCAAAAGTTGCTTCCCTTACCTTACACAATAAGGAGTTACAA
GATAAATTACAGGCCAAATCACCCAAGGAGGCGGAAGCAGACCTAAGCTTTGACTCATACCATTCCACCCAAACTGACTTGGGCCCATCC
CTGGGAAAACCTGGTGAAACCTCTCCCCCAGACTCCAAATCATCTCCATCTGTCTTAATACATTCTTTAGGTAAATCCACTACTGACAAT
GATGTCAGAATTCAGCAACTGCAAGAGATTTTGCAAGATCTACAGAAGAGATTAGAGAGCTCTGAAGCAGAGAGAAAACAGCTACAGGTC
GAACTCCAATCCCGAAGGGCAGAACTGGTATGCTTAAACAACACTGAGATTTCAGAGAACAGCTCTGACCTCAGCCAGAAACTTAAAGAA
ACTCAGAGCAAATACGAGGAGGCTATGAAAGAAGTCCTTAGTGTGCAGAAGCAGATGAAACTCGGTCTTGTCTCACCTGAAAGCATGGAT
AATTATTCACATTTCCACGAGCTGAGGGTCACGGAAGAGGAAATAAATGTGCTAAAGCAGGATCTGCAGAATGCATTAGAAGAAAGTGAA
AGAAATAAAGAGAAAGTGAGAGAGTTAGAGGAAAAACTGGTAGAGAGGGAGAAAGGTACAGTGATTAAGCCACCTGTGGAAGAGTACGAG
GAAATGAAAAGTTCATATTGCTCTGTTATTGAGAATATGAATAAGGAGAAAGCATTTTTGTTTGAGAAATACCAAGAAGCCCAAGAAGAA
ATCATGAAATTAAAAGACACACTAAAAAGTCAGATGACACAGGAAGCCAGTGATGAAGCTGAGGACATGAAAGAAGCCATGAATAGGATG
ATAGATGAACTCAATAAACAGGTGAGCGAGCTGTCACAGCTGTACAAAGAAGCCCAGGCTGAGCTGGAGGATTACAGGAAGAGGAAATCT
CTAGAGGATGTCACAGCTGAATATATCCATAAAGCAGAGCATGAGAAACTGATGCAATTGACAAACGTGTCCAGGGCTAAAGCAGAAGAT
GCACTGTCTGAAATGAAGTCTCAGTATTCAAAAGTGTTGAATGAGTTGACCCAGCTCAAACAACTGGTGGATGCACAAAAAGAGAACTCT
GTCTCTATCACAGAACATTTGCAAGTGATAACCACGCTGCGGACTGCAGCAAAAGAGATGGAAGAAAAAATAAGCAATCTTAAGGAACAC
CTTGCAAGCAAGGAAGTGGAAGTAGCAAAGCTGGAGAAACAACTCTTAGAAGAGAAAGCTGCTATGACTGATGCAATGGTACCTCGGTCT
TCCTATGAAAAACTCCAGTCATCCTTAGAGAGTGAAGTGAGTGTGTTGGCATCGAAATTAAAGGAATCTGTGAAAGAGAAAGAGAAGGTC
CATTCAGAGGTTGTCCAGATTAGAAGTGAGGTCTCACAGGTGAAAAGAGAAAAGGAAAATATTCAGACTCTCTTGAAATCCAAAGAGCAA
GAAGTAAATGAACTTCTGCAAAAATTCCAGCAAGCTCAGGAAGAACTTGCAGAAATGAAAAGATACGCTGAGAGCTCTTCAAAACTGGAG
GAAGATAAAGATAAAAAGATAAATGAGATGTCGAAGGAAGTCACCAAATTGAAGGAGGCCTTGAACAGCCTCTCCCAGCTCTCCTACTCA
ACAAGCTCATCCAAAAGGCAGAGTCAGCAGCTGGAGGCGCTGCAGCAGCAAGTCAAACAGCTCCAGAACCAGCTGGCGGAATGCAAGAAA
CAACACCAGGAGGTCATATCAGTTTACAGAATGCATCTTCTGTATGCTGTGCAGGGCCAGATGGATGAAGATGTCCAGAAAGTACTGAAG
CAAATCCTTACCATGTGTAAAAACCAGTCTCAAAAGAAGTAAAGTGGATTCCTTGGCAGGACACTGCCCCTTGTCATCTGTCTTTGTGTT
AGATCCAGAGTTGTCGGCAGCCGCTGCCATTGTTCTCATTCGTGGTATGCACTGTGGCCTAGCGTAGCTTCTTCCCTTTCCAAAGGTTTC
TGAGGACTTCTCCCAGGAGAAGACTGCCCGCCTCAGAACTGCTTAGAGACTTCAAACCAGCAGAGGTGAAAGTCCCTGTCATCCCTTCAG
ATTCCAGAGCTGGGATCAGCCATGCCCAGAGGTCTGGTCCTGATGCTGGCAGGGGGGCCCCCTCCTCCATCCCTGACTGGCTGAGTGGCT
TTATCACCACCGAGTGATGTGCTGAGGCCTCCTGCAGTGAATGCTCCTTCCATTCCTGTACTCGGGCAGTGCCATTCAGCACAGGAGAGC
TCTTTTTGCCTTTGGCTTTCAATTCCAAAACATGATTTAATTTCTAACTAAATTAGTATGGCACTAGTTATGAAGTATCTGCTTAAAACC
CTTCATCATGATATCCTGTGGATTTAAAAACTCTAATTCCATGTTTTCTTCCCATCTGCCTTATATATCTCATCACCCTGCTTATCAATA
TTCAGTTTGATGAGCACTATTAACTAAAATATGAAACTTAAAAACAAAAGCAAGTTGTCCTTAAAAGTTCTTTTTTTAAGTAAATTGTTG
ACATACTGCAAATTTTCTATGCAAACTTGCCTCCTGCTGTTATCTGTGAAGCTCAGGAAATCCAAACATTTGTGTTTCAACAAGGGACAG
TAAACTGTGTGTTTACAGCCAAAAGAAATGCCTCATAGTTCTTAACCTCAACTTTTGTAGAAGTATTTTTTTCTCTGTAATATTTTTATT
GGCTCATAAAGATGTTTTCATATCTGAACTCCTAAATAAGTGAAATTACAGTAGATTATATTAACAAAATACTTTTTAGGTAGCCATGCT
TGAGACTTTTTAAAAATATAACTTTTTCCTTAAAGTTTTCAGCTATAGCAAAAGGTAGTTATGTATGCCAGACCTAATATGAGCTGCCAC
CAACACCCCTAGAACTTTCAGCCATGGTGTCTTCAGAATTGTAGCGCATTTCTGAATCTAGCAAATCCTCCTTTTACCCGTTGAATGTTT
TGAATGCCCTGACTCTACCAGCGCCCATAAATGATCTCTAGAAGGACTGTTAGTACCAATCTGTTTTTCAACTTTGAAGCTAAAAACCCT
GATATGGTAATATTATGGTGCATAGCAGAGGTCTCGGAAAAAAAATATTTCTGTTCACTTTACTTTCAGGTTAAAAATGTTTCTAACACG
CTTGCAACTTCCCTTATGGCATTAATCTTGTTGAGGGAGAGAGACAGAATCCTGGACTCTCCAAAGTATTTAACTGAAAGTAGGGCCTGC
TCTGACAGGGCCCATGTCCCACAAGGCTGCTTGGCCTCAGTGGGTGCTTGGCTGTGCTGGATGATATGTTGATCTGTATTGGATAAGGAC
CAATGACAGCAAAGCAAAAATGGCTTTAAAGCTTGGTGTTACTTTTCTTAAGTTGTTTAATTATAGTTAAGCAATTTCAAAAATGCTCCA
AAGAAATGTGAAAGGACCTTTTGTCACAGCACTTCAGAAAATACACAACAGCCCCTTCTGCCCCCGCACAGAAATGCTGCAGAGTATATA
AAACTTGAGACATTTTTGTAGGATGCCTGACGAGGTGTAGCCTTTTATCTTGTTTCCGGATGCATATTTATTACGAGTACTCTGGTTAAA
TATTGAAAAGTTATATGCTGTAGTTTTTAGTATTTTGTCTTTGTAATTTACAGAAGTTATTGGAGAAAATAAACTTGTTTCATTTTGC

>2045_2045_8_ADAMTS12-RAI14_ADAMTS12_chr5_33881224_ENST00000504830_RAI14_chr5_34757573_ENST00000428746_length(amino acids)=1131AA_BP=163
MPCAQRSWLANLSVVAQLLNFGALCYGRQPQPGPVRFPDRRQEHFIKGLPEYHVVGPVRVDASGHFLSYGLHYPITSSRRKRDLDGSEDW
VYYRISHEEKDLFFNLTVNQGFLSNSYIMEKRYGNLSHVKMMASSAPLCHLSGTVLQQGTRVGTAALSACHGLTNEWNKNDDRLLQAVEN
GDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSG
KTALHYAAAQGCLQAVQILCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEALIKKGA
DLNLVDSLGYNALHYSKLSENAGIQSLLLSKISQDADLKTPTKPKQHDQVSKISSERSGTPKKRKAPPPPISPTQLSDVSSPRSITSTPL
SGKESVFFAEPPFKAEISSIRENKDRLSDSTTGADSLLDISSEADQQDLLSLLQAKVASLTLHNKELQDKLQAKSPKEAEADLSFDSYHS
TQTDLGPSLGKPGETSPPDSKSSPSVLIHSLGKSTTDNDVRIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNNTEISENSS
DLSQKLKETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNYSHFHELRVTEEEINVLKQDLQNALEESERNKEKVRELEEKLVEREKGTVI
KPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAEL
EDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEE
KISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIRSEVSQVKREKENIQ
TLLKSKEQEVNELLQKFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQ
NQLAECKKQHQEVISVYRMHLLYAVQGQMDEDVQKVLKQILTMCKNQSQKK

--------------------------------------------------------------
>2045_2045_9_ADAMTS12-RAI14_ADAMTS12_chr5_33881224_ENST00000504830_RAI14_chr5_34757573_ENST00000503673_length(transcript)=3772nt_BP=825nt
GAGCGGGCGGGCTGCGAGGCCGCGGGGCATGCGGGAGGCGGAGGGGTGGGGACCGGGGTGGGCTGCGCCCTCCCGCTCTGGCCCATTCCA
CACCCCGCCGAAAGCGGACACTGTCAGCTGAATCACTCCCCTTTTAGGAGGAGGGAGGGGAAAAAGGTGTCTAGCTCCTTTCTGCTTAAA
AAAGCACAGGGAGATCGCGGGCAGCTTTGCAGTCGCTGCCTTCTCGCGCCTGACCATGCACCCCTGCATCTTCCTGCTGGGCCACAGGCG
AGCGCTTTATTTCTGGAGCTGAGGGCTAAAACTTTTTTGACTTTTCTTCTCCTCAACATCTGAATCATGCCATGTGCCCAGAGGAGCTGG
CTTGCAAACCTTTCCGTGGTGGCTCAGCTCCTTAACTTTGGGGCGCTTTGCTATGGGAGACAGCCTCAGCCAGGCCCGGTTCGCTTCCCG
GACAGGAGGCAAGAGCATTTTATCAAGGGCCTGCCAGAATACCACGTGGTGGGTCCAGTCCGAGTAGATGCCAGTGGGCATTTTTTGTCA
TATGGCTTGCACTATCCCATCACGAGCAGCAGGAGGAAGAGAGATTTGGATGGCTCAGAGGACTGGGTGTACTACAGAATTTCTCACGAG
GAGAAGGACCTGTTTTTTAACTTGACGGTCAATCAAGGATTTCTTTCCAATAGCTACATCATGGAGAAGAGATATGGGAACCTCTCCCAT
GTTAAGATGATGGCTTCCTCTGCCCCCCTCTGCCATCTCAGTGGCACGGTTCTACAGCAGGGCACCAGAGTTGGGACGGCAGCCCTCAGT
GCCTGCCATGGACTGACCAATGAGTGGAACAAGAATGATGACCGGCTACTGCAGGCCGTGGAGAATGGAGATGCGGAGAAGGTGGCCTCA
CTGCTCGGCAAGAAGGGGGCCAGTGCCACCAAACACGACAGTGAGGGCAAGACCGCTTTCCATCTTGCTGCTGCAAAAGGACACGTGGAA
TGCCTCAGGGTCATGATTACACATGGTGTGGATGTGACAGCCCAAGATACTACCGGACACAGCGCCTTACATCTCGCAGCCAAGAACAGC
CACCATGAATGCATCAGGAAGCTGCTTCAGTCTAAATGCCCAGCCGAAAGTGTCGACAGCTCTGGGAAAACAGCTTTACATTATGCAGCG
GCTCAGGGCTGCCTTCAAGCTGTGCAGATTCTCTGCGAACACAAGAGCCCCATAAACCTCAAAGATTTGGATGGGAATATACCGCTGCTT
CTTGCTGTACAAAATGGTCACAGTGAGATCTGTCACTTTCTCCTGGATCATGGAGCAGATGTCAATTCCAGGAACAAAAGTGGAAGAACT
GCTCTCATGCTGGCCTGTGAGATTGGCAGCTCTAACGCTGTGGAAGCCTTAATTAAAAAGGGTGCAGACCTAAACCTTGTAGATTCTCTT
GGATACAATGCCTTACATTATTCCAAACTCTCAGAAAATGCAGGAATTCAAAGCCTTCTATTATCAAAAATCTCTCAGGATGCTGATTTA
AAGACCCCAACAAAACCAAAGCAGCATGACCAAGTCTCTAAAATAAGCTCAGAAAGAAGTGGAACTCCAAAAAAACGCAAAGCTCCACCA
CCTCCTATCAGTCCTACCCAGTTGAGTGATGTCTCTTCCCCAAGATCAATAACTTCGACTCCACTATCGGGAAAGGAATCGGTATTTTTT
GCTGAACCACCCTTCAAGGCTGAGATCAGTTCTATACGAGAAAACAAAGACAGACTAAGTGACAGTACTACAGGTGCTGATAGCTTATTG
GATATAAGTTCTGAAGCTGACCAACAAGATCTTCTCTCTCTATTGCAAGCAAAAGTTGCTTCCCTTACCTTACACAATAAGGAGTTACAA
GATAAATTACAGGCCAAATCACCCAAGGAGGCGGAAGCAGACCTAAGCTTTGACTCATACCATTCCACCCAAACTGACTTGGGCCCATCC
CTGGGAAAACCTGGTGAAACCTCTCCCCCAGACTCCAAATCATCTCCATCTGTCTTAATACATTCTTTAGGTAAATCCACTACTGACAAT
GATGTCAGAATTCAGCAACTGCAAGAGATTTTGCAAGATCTACAGAAGAGATTAGAGAGCTCTGAAGCAGAGAGAAAACAGCTACAGGTC
GAACTCCAATCCCGAAGGGCAGAACTGGTATGCTTAAACAACACTGAGATTTCAGAGAACAGCTCTGACCTCAGCCAGAAACTTAAAGAA
ACTCAGAGCAAATACGAGGAGGCTATGAAAGAAGTCCTTAGTGTGCAGAAGCAGATGAAACTCGGTCTTGTCTCACCTGAAAGCATGGAT
AATTATTCACATTTCCACGAGCTGAGGGTCACGGAAGAGGAAATAAATGTGCTAAAGCAGGATCTGCAGAATGCATTAGAAGAAAGTGAA
AGAAATAAAGAGAAAGTGAGAGAGTTAGAGGAAAAACTGGTAGAGAGGGAGAAAGGTACAGTGATTAAGCCACCTGTGGAAGAGTACGAG
GAAATGAAAAGTTCATATTGCTCTGTTATTGAGAATATGAATAAGGAGAAAGCATTTTTGTTTGAGAAATACCAAGAAGCCCAAGAAGAA
ATCATGAAATTAAAAGACACACTAAAAAGTCAGATGACACAGGAAGCCAGTGATGAAGCTGAGGACATGAAAGAAGCCATGAATAGGATG
ATAGATGAACTCAATAAACAGGTGAGCGAGCTGTCACAGCTGTACAAAGAAGCCCAGGCTGAGCTGGAGGATTACAGGAAGAGGAAATCT
CTAGAGGATGTCACAGCTGAATATATCCATAAAGCAGAGCATGAGAAACTGATGCAATTGACAAACGTGTCCAGGGCTAAAGCAGAAGAT
GCACTGTCTGAAATGAAGTCTCAGTATTCAAAAGTGTTGAATGAGTTGACCCAGCTCAAACAACTGGTGGATGCACAAAAAGAGAACTCT
GTCTCTATCACAGAACATTTGCAAGTGATAACCACGCTGCGGACTGCAGCAAAAGAGATGGAAGAAAAAATAAGCAATCTTAAGGAACAC
CTTGCAAGCAAGGAAGTGGAAGTAGCAAAGCTGGAGAAACAACTCTTAGAAGAGAAAGCTGCTATGACTGATGCAATGGTACCTCGGTCT
TCCTATGAAAAACTCCAGTCATCCTTAGAGAGTGAAGTGAGTGTGTTGGCATCGAAATTAAAGGAATCTGTGAAAGAGAAAGAGAAGGTC
CATTCAGAGGTTGTCCAGATTAGAAGTGAGGTCTCACAGGTGAAAAGAGAAAAGGAAAATATTCAGACTCTCTTGAAATCCAAAGAGCAA
GAAGTAAATGAACTTCTGCAAAAATTCCAGCAAGCTCAGGAAGAACTTGCAGAAATGAAAAGATACGCTGAGAGCTCTTCAAAACTGGAG
GAAGATAAAGATAAAAAGATAAATGAGATGTCGAAGGAAGTCACCAAATTGAAGGAGGCCTTGAACAGCCTCTCCCAGCTCTCCTACTCA
ACAAGCTCATCCAAAAGGCAGAGTCAGCAGCTGGAGGCGCTGCAGCAGCAAGTCAAACAGCTCCAGAACCAGCTGGCGGAATGCAAGAAA
CAACACCAGGAGGTCATATCAGTTTACAGAATGCATCTTCTGTATGCTGTGCAGGGCCAGATGGATGAAGATGTCCAGAAAGTACTGAAG
CAAATCCTTACCATGTGTAAAAACCAGTCTCAAAAGAAGTAAAGTGGATTCCTTGGCAGGACACTGCCCCTTGTCATCTGTC

>2045_2045_9_ADAMTS12-RAI14_ADAMTS12_chr5_33881224_ENST00000504830_RAI14_chr5_34757573_ENST00000503673_length(amino acids)=1131AA_BP=163
MPCAQRSWLANLSVVAQLLNFGALCYGRQPQPGPVRFPDRRQEHFIKGLPEYHVVGPVRVDASGHFLSYGLHYPITSSRRKRDLDGSEDW
VYYRISHEEKDLFFNLTVNQGFLSNSYIMEKRYGNLSHVKMMASSAPLCHLSGTVLQQGTRVGTAALSACHGLTNEWNKNDDRLLQAVEN
GDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSG
KTALHYAAAQGCLQAVQILCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEALIKKGA
DLNLVDSLGYNALHYSKLSENAGIQSLLLSKISQDADLKTPTKPKQHDQVSKISSERSGTPKKRKAPPPPISPTQLSDVSSPRSITSTPL
SGKESVFFAEPPFKAEISSIRENKDRLSDSTTGADSLLDISSEADQQDLLSLLQAKVASLTLHNKELQDKLQAKSPKEAEADLSFDSYHS
TQTDLGPSLGKPGETSPPDSKSSPSVLIHSLGKSTTDNDVRIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNNTEISENSS
DLSQKLKETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNYSHFHELRVTEEEINVLKQDLQNALEESERNKEKVRELEEKLVEREKGTVI
KPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAEL
EDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEE
KISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIRSEVSQVKREKENIQ
TLLKSKEQEVNELLQKFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQ
NQLAECKKQHQEVISVYRMHLLYAVQGQMDEDVQKVLKQILTMCKNQSQKK

--------------------------------------------------------------
>2045_2045_10_ADAMTS12-RAI14_ADAMTS12_chr5_33881224_ENST00000504830_RAI14_chr5_34757573_ENST00000506376_length(transcript)=3752nt_BP=825nt
GAGCGGGCGGGCTGCGAGGCCGCGGGGCATGCGGGAGGCGGAGGGGTGGGGACCGGGGTGGGCTGCGCCCTCCCGCTCTGGCCCATTCCA
CACCCCGCCGAAAGCGGACACTGTCAGCTGAATCACTCCCCTTTTAGGAGGAGGGAGGGGAAAAAGGTGTCTAGCTCCTTTCTGCTTAAA
AAAGCACAGGGAGATCGCGGGCAGCTTTGCAGTCGCTGCCTTCTCGCGCCTGACCATGCACCCCTGCATCTTCCTGCTGGGCCACAGGCG
AGCGCTTTATTTCTGGAGCTGAGGGCTAAAACTTTTTTGACTTTTCTTCTCCTCAACATCTGAATCATGCCATGTGCCCAGAGGAGCTGG
CTTGCAAACCTTTCCGTGGTGGCTCAGCTCCTTAACTTTGGGGCGCTTTGCTATGGGAGACAGCCTCAGCCAGGCCCGGTTCGCTTCCCG
GACAGGAGGCAAGAGCATTTTATCAAGGGCCTGCCAGAATACCACGTGGTGGGTCCAGTCCGAGTAGATGCCAGTGGGCATTTTTTGTCA
TATGGCTTGCACTATCCCATCACGAGCAGCAGGAGGAAGAGAGATTTGGATGGCTCAGAGGACTGGGTGTACTACAGAATTTCTCACGAG
GAGAAGGACCTGTTTTTTAACTTGACGGTCAATCAAGGATTTCTTTCCAATAGCTACATCATGGAGAAGAGATATGGGAACCTCTCCCAT
GTTAAGATGATGGCTTCCTCTGCCCCCCTCTGCCATCTCAGTGGCACGGTTCTACAGCAGGGCACCAGAGTTGGGACGGCAGCCCTCAGT
GCCTGCCATGGACTGACCAATGAGTGGAACAAGAATGATGACCGGCTACTGCAGGCCGTGGAGAATGGAGATGCGGAGAAGGTGGCCTCA
CTGCTCGGCAAGAAGGGGGCCAGTGCCACCAAACACGACAGTGAGGGCAAGACCGCTTTCCATCTTGCTGCTGCAAAAGGACACGTGGAA
TGCCTCAGGGTCATGATTACACATGGTGTGGATGTGACAGCCCAAGATACTACCGGACACAGCGCCTTACATCTCGCAGCCAAGAACAGC
CACCATGAATGCATCAGGAAGCTGCTTCAGTCTAAATGCCCAGCCGAAAGTGTCGACAGCTCTGGGAAAACAGCTTTACATTATGCAGCG
GCTCAGGGCTGCCTTCAAGCTGTGCAGATTCTCTGCGAACACAAGAGCCCCATAAACCTCAAAGATTTGGATGGGAATATACCGCTGCTT
CTTGCTGTACAAAATGGTCACAGTGAGATCTGTCACTTTCTCCTGGATCATGGAGCAGATGTCAATTCCAGGAACAAAAGTGGAAGAACT
GCTCTCATGCTGGCCTGTGAGATTGGCAGCTCTAACGCTGTGGAAGCCTTAATTAAAAAGGGTGCAGACCTAAACCTTGTAGATTCTCTT
GGATACAATGCCTTACATTATTCCAAACTCTCAGAAAATGCAGGAATTCAAAGCCTTCTATTATCAAAAATCTCTCAGGATGCTGATTTA
AAGACCCCAACAAAACCAAAGCAGCATGACCAAGTCTCTAAAATAAGCTCAGAAAGAAGTGGAACTCCAAAAAAACGCAAAGCTCCACCA
CCTCCTATCAGTCCTACCCAGTTGAGTGATGTCTCTTCCCCAAGATCAATAACTTCGACTCCACTATCGGGAAAGGAATCGGTATTTTTT
GCTGAACCACCCTTCAAGGCTGAGATCAGTTCTATACGAGAAAACAAAGACAGACTAAGTGACAGTACTACAGGTGCTGATAGCTTATTG
GATATAAGTTCTGAAGCTGACCAACAAGATCTTCTCTCTCTATTGCAAGCAAAAGTTGCTTCCCTTACCTTACACAATAAGGAGTTACAA
GATAAATTACAGGCCAAATCACCCAAGGAGGCGGAAGCAGACCTAAGCTTTGACTCATACCATTCCACCCAAACTGACTTGGGCCCATCC
CTGGGAAAACCTGGTGAAACCTCTCCCCCAGACTCCAAATCATCTCCATCTGTCTTAATACATTCTTTAGGTAAATCCACTACTGACAAT
GATGTCAGAATTCAGCAACTGCAAGAGATTTTGCAAGATCTACAGAAGAGATTAGAGAGCTCTGAAGCAGAGAGAAAACAGCTACAGGTC
GAACTCCAATCCCGAAGGGCAGAACTGGTATGCTTAAACAACACTGAGATTTCAGAGAACAGCTCTGACCTCAGCCAGAAACTTAAAGAA
ACTCAGAGCAAATACGAGGAGGCTATGAAAGAAGTCCTTAGTGTGCAGAAGCAGATGAAACTCGGTCTTGTCTCACCTGAAAGCATGGAT
AATTATTCACATTTCCACGAGCTGAGGGTCACGGAAGAGGAAATAAATGTGCTAAAGCAGGATCTGCAGAATGCATTAGAAGAAAGTGAA
AGAAATAAAGAGAAAGTGAGAGAGTTAGAGGAAAAACTGGTAGAGAGGGAGAAAGGTACAGTGATTAAGCCACCTGTGGAAGAGTACGAG
GAAATGAAAAGTTCATATTGCTCTGTTATTGAGAATATGAATAAGGAGAAAGCATTTTTGTTTGAGAAATACCAAGAAGCCCAAGAAGAA
ATCATGAAATTAAAAGACACACTAAAAAGTCAGATGACACAGGAAGCCAGTGATGAAGCTGAGGACATGAAAGAAGCCATGAATAGGATG
ATAGATGAACTCAATAAACAGGTGAGCGAGCTGTCACAGCTGTACAAAGAAGCCCAGGCTGAGCTGGAGGATTACAGGAAGAGGAAATCT
CTAGAGGATGTCACAGCTGAATATATCCATAAAGCAGAGCATGAGAAACTGATGCAATTGACAAACGTGTCCAGGGCTAAAGCAGAAGAT
GCACTGTCTGAAATGAAGTCTCAGTATTCAAAAGTGTTGAATGAGTTGACCCAGCTCAAACAACTGGTGGATGCACAAAAAGAGAACTCT
GTCTCTATCACAGAACATTTGCAAGTGATAACCACGCTGCGGACTGCAGCAAAAGAGATGGAAGAAAAAATAAGCAATCTTAAGGAACAC
CTTGCAAGCAAGGAAGTGGAAGTAGCAAAGCTGGAGAAACAACTCTTAGAAGAGAAAGCTGCTATGACTGATGCAATGGTACCTCGGTCT
TCCTATGAAAAACTCCAGTCATCCTTAGAGAGTGAAGTGAGTGTGTTGGCATCGAAATTAAAGGAATCTGTGAAAGAGAAAGAGAAGGTC
CATTCAGAGGTTGTCCAGATTAGAAGTGAGGTCTCACAGGTGAAAAGAGAAAAGGAAAATATTCAGACTCTCTTGAAATCCAAAGAGCAA
GAAGTAAATGAACTTCTGCAAAAATTCCAGCAAGCTCAGGAAGAACTTGCAGAAATGAAAAGATACGCTGAGAGCTCTTCAAAACTGGAG
GAAGATAAAGATAAAAAGATAAATGAGATGTCGAAGGAAGTCACCAAATTGAAGGAGGCCTTGAACAGCCTCTCCCAGCTCTCCTACTCA
ACAAGCTCATCCAAAAGGCAGAGTCAGCAGCTGGAGGCGCTGCAGCAGCAAGTCAAACAGCTCCAGAACCAGCTGGCGGAATGCAAGAAA
CAACACCAGGAGGTCATATCAGTTTACAGAATGCATCTTCTGTATGCTGTGCAGGGCCAGATGGATGAAGATGTCCAGAAAGTACTGAAG
CAAATCCTTACCATGTGTAAAAACCAGTCTCAAAAGAAGTAAAGTGGATTCCTTGGCAGGAC

>2045_2045_10_ADAMTS12-RAI14_ADAMTS12_chr5_33881224_ENST00000504830_RAI14_chr5_34757573_ENST00000506376_length(amino acids)=1131AA_BP=163
MPCAQRSWLANLSVVAQLLNFGALCYGRQPQPGPVRFPDRRQEHFIKGLPEYHVVGPVRVDASGHFLSYGLHYPITSSRRKRDLDGSEDW
VYYRISHEEKDLFFNLTVNQGFLSNSYIMEKRYGNLSHVKMMASSAPLCHLSGTVLQQGTRVGTAALSACHGLTNEWNKNDDRLLQAVEN
GDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSG
KTALHYAAAQGCLQAVQILCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEALIKKGA
DLNLVDSLGYNALHYSKLSENAGIQSLLLSKISQDADLKTPTKPKQHDQVSKISSERSGTPKKRKAPPPPISPTQLSDVSSPRSITSTPL
SGKESVFFAEPPFKAEISSIRENKDRLSDSTTGADSLLDISSEADQQDLLSLLQAKVASLTLHNKELQDKLQAKSPKEAEADLSFDSYHS
TQTDLGPSLGKPGETSPPDSKSSPSVLIHSLGKSTTDNDVRIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNNTEISENSS
DLSQKLKETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNYSHFHELRVTEEEINVLKQDLQNALEESERNKEKVRELEEKLVEREKGTVI
KPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAEL
EDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEE
KISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIRSEVSQVKREKENIQ
TLLKSKEQEVNELLQKFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQ
NQLAECKKQHQEVISVYRMHLLYAVQGQMDEDVQKVLKQILTMCKNQSQKK

--------------------------------------------------------------
>2045_2045_11_ADAMTS12-RAI14_ADAMTS12_chr5_33881224_ENST00000504830_RAI14_chr5_34757573_ENST00000512629_length(transcript)=3645nt_BP=825nt
GAGCGGGCGGGCTGCGAGGCCGCGGGGCATGCGGGAGGCGGAGGGGTGGGGACCGGGGTGGGCTGCGCCCTCCCGCTCTGGCCCATTCCA
CACCCCGCCGAAAGCGGACACTGTCAGCTGAATCACTCCCCTTTTAGGAGGAGGGAGGGGAAAAAGGTGTCTAGCTCCTTTCTGCTTAAA
AAAGCACAGGGAGATCGCGGGCAGCTTTGCAGTCGCTGCCTTCTCGCGCCTGACCATGCACCCCTGCATCTTCCTGCTGGGCCACAGGCG
AGCGCTTTATTTCTGGAGCTGAGGGCTAAAACTTTTTTGACTTTTCTTCTCCTCAACATCTGAATCATGCCATGTGCCCAGAGGAGCTGG
CTTGCAAACCTTTCCGTGGTGGCTCAGCTCCTTAACTTTGGGGCGCTTTGCTATGGGAGACAGCCTCAGCCAGGCCCGGTTCGCTTCCCG
GACAGGAGGCAAGAGCATTTTATCAAGGGCCTGCCAGAATACCACGTGGTGGGTCCAGTCCGAGTAGATGCCAGTGGGCATTTTTTGTCA
TATGGCTTGCACTATCCCATCACGAGCAGCAGGAGGAAGAGAGATTTGGATGGCTCAGAGGACTGGGTGTACTACAGAATTTCTCACGAG
GAGAAGGACCTGTTTTTTAACTTGACGGTCAATCAAGGATTTCTTTCCAATAGCTACATCATGGAGAAGAGATATGGGAACCTCTCCCAT
GTTAAGATGATGGCTTCCTCTGCCCCCCTCTGCCATCTCAGTGGCACGGTTCTACAGCAGGGCACCAGAGTTGGGACGGCAGCCCTCAGT
GCCTGCCATGGACTGACCAATGAGTGGAACAAGAATGATGACCGGCTACTGCAGGCCGTGGAGAATGGAGATGCGGAGAAGGTGGCCTCA
CTGCTCGGCAAGAAGGGGGCCAGTGCCACCAAACACGACAGTGAGGGCAAGACCGCTTTCCATCTTGCTGCTGCAAAAGGACACGTGGAA
TGCCTCAGGGTCATGATTACACATGGTGTGGATGTGACAGCCCAAGATACTACCGGACACAGCGCCTTACATCTCGCAGCCAAGAACAGC
CACCATGAATGCATCAGGAAGCTGCTTCAGTCTAAATGCCCAGCCGAAAGTGTCGACAGCTCTGGGAAAACAGCTTTACATTATGCAGCG
GCTCAGGGCTGCCTTCAAGCTGTGCAGATTCTCTGCGAACACAAGAGCCCCATAAACCTCAAAGATTTGGATGGGAATATACCGCTGCTT
CTTGCTGTACAAAATGGTCACAGTGAGATCTGTCACTTTCTCCTGGATCATGGAGCAGATGTCAATTCCAGGAACAAAAGTGGAAGAACT
GCTCTCATGCTGGCCTGTGAGATTGGCAGCTCTAACGCTGTGGAAGCCTTAATTAAAAAGGGTGCAGACCTAAACCTTGTAGATTCTCTT
GGATACAATGCCTTACATTATTCCAAACTCTCAGAAAATGCAGGAATTCAAAGCCTTCTATTATCAAAAATCTCTCAGGATGCTGATTTA
AAGACCCCAACAAAACCAAAGCAGTTGAGTGATGTCTCTTCCCCAAGATCAATAACTTCGACTCCACTATCGGGAAAGGAATCGGTATTT
TTTGCTGAACCACCCTTCAAGGCTGAGATCAGTTCTATACGAGAAAACAAAGACAGACTAAGTGACAGTACTACAGGTGCTGATAGCTTA
TTGGATATAAGTTCTGAAGCTGACCAACAAGATCTTCTCTCTCTATTGCAAGCAAAAGTTGCTTCCCTTACCTTACACAATAAGGAGTTA
CAAGATAAATTACAGGCCAAATCACCCAAGGAGGCGGAAGCAGACCTAAGCTTTGACTCATACCATTCCACCCAAACTGACTTGGGCCCA
TCCCTGGGAAAACCTGGTGAAACCTCTCCCCCAGACTCCAAATCATCTCCATCTGTCTTAATACATTCTTTAGGTAAATCCACTACTGAC
AATGATGTCAGAATTCAGCAACTGCAAGAGATTTTGCAAGATCTACAGAAGAGATTAGAGAGCTCTGAAGCAGAGAGAAAACAGCTACAG
GTCGAACTCCAATCCCGAAGGGCAGAACTGGTATGCTTAAACAACACTGAGATTTCAGAGAACAGCTCTGACCTCAGCCAGAAACTTAAA
GAAACTCAGAGCAAATACGAGGAGGCTATGAAAGAAGTCCTTAGTGTGCAGAAGCAGATGAAACTCGGTCTTGTCTCACCTGAAAGCATG
GATAATTATTCACATTTCCACGAGCTGAGGGTCACGGAAGAGGAAATAAATGTGCTAAAGCAGGATCTGCAGAATGCATTAGAAGAAAGT
GAAAGAAATAAAGAGAAAGTGAGAGAGTTAGAGGAAAAACTGGTAGAGAGGGAGAAAGGTACAGTGATTAAGCCACCTGTGGAAGAGTAC
GAGGAAATGAAAAGTTCATATTGCTCTGTTATTGAGAATATGAATAAGGAGAAAGCATTTTTGTTTGAGAAATACCAAGAAGCCCAAGAA
GAAATCATGAAATTAAAAGACACACTAAAAAGTCAGATGACACAGGAAGCCAGTGATGAAGCTGAGGACATGAAAGAAGCCATGAATAGG
ATGATAGATGAACTCAATAAACAGGTGAGCGAGCTGTCACAGCTGTACAAAGAAGCCCAGGCTGAGCTGGAGGATTACAGGAAGAGGAAA
TCTCTAGAGGATGTCACAGCTGAATATATCCATAAAGCAGAGCATGAGAAACTGATGCAATTGACAAACGTGTCCAGGGCTAAAGCAGAA
GATGCACTGTCTGAAATGAAGTCTCAGTATTCAAAAGTGTTGAATGAGTTGACCCAGCTCAAACAACTGGTGGATGCACAAAAAGAGAAC
TCTGTCTCTATCACAGAACATTTGCAAGTGATAACCACGCTGCGGACTGCAGCAAAAGAGATGGAAGAAAAAATAAGCAATCTTAAGGAA
CACCTTGCAAGCAAGGAAGTGGAAGTAGCAAAGCTGGAGAAACAACTCTTAGAAGAGAAAGCTGCTATGACTGATGCAATGGTACCTCGG
TCTTCCTATGAAAAACTCCAGTCATCCTTAGAGAGTGAAGTGAGTGTGTTGGCATCGAAATTAAAGGAATCTGTGAAAGAGAAAGAGAAG
GTCCATTCAGAGGTTGTCCAGATTAGAAGTGAGGTCTCACAGGTGAAAAGAGAAAAGGAAAATATTCAGACTCTCTTGAAATCCAAAGAG
CAAGAAGTAAATGAACTTCTGCAAAAATTCCAGCAAGCTCAGGAAGAACTTGCAGAAATGAAAAGATACGCTGAGAGCTCTTCAAAACTG
GAGGAAGATAAAGATAAAAAGATAAATGAGATGTCGAAGGAAGTCACCAAATTGAAGGAGGCCTTGAACAGCCTCTCCCAGCTCTCCTAC
TCAACAAGCTCATCCAAAAGGCAGAGTCAGCAGCTGGAGGCGCTGCAGCAGCAAGTCAAACAGCTCCAGAACCAGCTGGCGGAATGCAAG
AAACAACACCAGGAGGTCATATCAGTTTACAGAATGCATCTTCTGTATGCTGTGCAGGGCCAGATGGATGAAGATGTCCAGAAAGTACTG
AAGCAAATCCTTACCATGTGTAAAAACCAGTCTCAAAAGAAGTAA

>2045_2045_11_ADAMTS12-RAI14_ADAMTS12_chr5_33881224_ENST00000504830_RAI14_chr5_34757573_ENST00000512629_length(amino acids)=1102AA_BP=163
MPCAQRSWLANLSVVAQLLNFGALCYGRQPQPGPVRFPDRRQEHFIKGLPEYHVVGPVRVDASGHFLSYGLHYPITSSRRKRDLDGSEDW
VYYRISHEEKDLFFNLTVNQGFLSNSYIMEKRYGNLSHVKMMASSAPLCHLSGTVLQQGTRVGTAALSACHGLTNEWNKNDDRLLQAVEN
GDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSG
KTALHYAAAQGCLQAVQILCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEALIKKGA
DLNLVDSLGYNALHYSKLSENAGIQSLLLSKISQDADLKTPTKPKQLSDVSSPRSITSTPLSGKESVFFAEPPFKAEISSIRENKDRLSD
STTGADSLLDISSEADQQDLLSLLQAKVASLTLHNKELQDKLQAKSPKEAEADLSFDSYHSTQTDLGPSLGKPGETSPPDSKSSPSVLIH
SLGKSTTDNDVRIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNNTEISENSSDLSQKLKETQSKYEEAMKEVLSVQKQMKL
GLVSPESMDNYSHFHELRVTEEEINVLKQDLQNALEESERNKEKVRELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLF
EKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSLEDVTAEYIHKAEHEKLMQLT
NVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAA
MTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIRSEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKR
YAESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQNQLAECKKQHQEVISVYRMHLLYAVQGQM
DEDVQKVLKQILTMCKNQSQKK

--------------------------------------------------------------
>2045_2045_12_ADAMTS12-RAI14_ADAMTS12_chr5_33881224_ENST00000504830_RAI14_chr5_34757573_ENST00000515799_length(transcript)=3774nt_BP=825nt
GAGCGGGCGGGCTGCGAGGCCGCGGGGCATGCGGGAGGCGGAGGGGTGGGGACCGGGGTGGGCTGCGCCCTCCCGCTCTGGCCCATTCCA
CACCCCGCCGAAAGCGGACACTGTCAGCTGAATCACTCCCCTTTTAGGAGGAGGGAGGGGAAAAAGGTGTCTAGCTCCTTTCTGCTTAAA
AAAGCACAGGGAGATCGCGGGCAGCTTTGCAGTCGCTGCCTTCTCGCGCCTGACCATGCACCCCTGCATCTTCCTGCTGGGCCACAGGCG
AGCGCTTTATTTCTGGAGCTGAGGGCTAAAACTTTTTTGACTTTTCTTCTCCTCAACATCTGAATCATGCCATGTGCCCAGAGGAGCTGG
CTTGCAAACCTTTCCGTGGTGGCTCAGCTCCTTAACTTTGGGGCGCTTTGCTATGGGAGACAGCCTCAGCCAGGCCCGGTTCGCTTCCCG
GACAGGAGGCAAGAGCATTTTATCAAGGGCCTGCCAGAATACCACGTGGTGGGTCCAGTCCGAGTAGATGCCAGTGGGCATTTTTTGTCA
TATGGCTTGCACTATCCCATCACGAGCAGCAGGAGGAAGAGAGATTTGGATGGCTCAGAGGACTGGGTGTACTACAGAATTTCTCACGAG
GAGAAGGACCTGTTTTTTAACTTGACGGTCAATCAAGGATTTCTTTCCAATAGCTACATCATGGAGAAGAGATATGGGAACCTCTCCCAT
GTTAAGATGATGGCTTCCTCTGCCCCCCTCTGCCATCTCAGTGGCACGGTTCTACAGCAGGGCACCAGAGTTGGGACGGCAGCCCTCAGT
GCCTGCCATGGACTGACCAATGAGTGGAACAAGAATGATGACCGGCTACTGCAGGCCGTGGAGAATGGAGATGCGGAGAAGGTGGCCTCA
CTGCTCGGCAAGAAGGGGGCCAGTGCCACCAAACACGACAGTGAGGGCAAGACCGCTTTCCATCTTGCTGCTGCAAAAGGACACGTGGAA
TGCCTCAGGGTCATGATTACACATGGTGTGGATGTGACAGCCCAAGATACTACCGGACACAGCGCCTTACATCTCGCAGCCAAGAACAGC
CACCATGAATGCATCAGGAAGCTGCTTCAGTCTAAATGCCCAGCCGAAAGTGTCGACAGCTCTGGGAAAACAGCTTTACATTATGCAGCG
GCTCAGGGCTGCCTTCAAGCTGTGCAGATTCTCTGCGAACACAAGAGCCCCATAAACCTCAAAGATTTGGATGGGAATATACCGCTGCTT
CTTGCTGTACAAAATGGTCACAGTGAGATCTGTCACTTTCTCCTGGATCATGGAGCAGATGTCAATTCCAGGAACAAAAGTGGAAGAACT
GCTCTCATGCTGGCCTGTGAGATTGGCAGCTCTAACGCTGTGGAAGCCTTAATTAAAAAGGGTGCAGACCTAAACCTTGTAGATTCTCTT
GGATACAATGCCTTACATTATTCCAAACTCTCAGAAAATGCAGGAATTCAAAGCCTTCTATTATCAAAAATCTCTCAGGATGCTGATTTA
AAGACCCCAACAAAACCAAAGCAGCATGACCAAGTCTCTAAAATAAGCTCAGAAAGAAGTGGAACTCCAAAAAAACGCAAAGCTCCACCA
CCTCCTATCAGTCCTACCCAGTTGAGTGATGTCTCTTCCCCAAGATCAATAACTTCGACTCCACTATCGGGAAAGGAATCGGTATTTTTT
GCTGAACCACCCTTCAAGGCTGAGATCAGTTCTATACGAGAAAACAAAGACAGACTAAGTGACAGTACTACAGGTGCTGATAGCTTATTG
GATATAAGTTCTGAAGCTGACCAACAAGATCTTCTCTCTCTATTGCAAGCAAAAGTTGCTTCCCTTACCTTACACAATAAGGAGTTACAA
GATAAATTACAGGCCAAATCACCCAAGGAGGCGGAAGCAGACCTAAGCTTTGACTCATACCATTCCACCCAAACTGACTTGGGCCCATCC
CTGGGAAAACCTGGTGAAACCTCTCCCCCAGACTCCAAATCATCTCCATCTGTCTTAATACATTCTTTAGGTAAATCCACTACTGACAAT
GATGTCAGAATTCAGCAACTGCAAGAGATTTTGCAAGATCTACAGAAGAGATTAGAGAGCTCTGAAGCAGAGAGAAAACAGCTACAGGTC
GAACTCCAATCCCGAAGGGCAGAACTGGTATGCTTAAACAACACTGAGATTTCAGAGAACAGCTCTGACCTCAGCCAGAAACTTAAAGAA
ACTCAGAGCAAATACGAGGAGGCTATGAAAGAAGTCCTTAGTGTGCAGAAGCAGATGAAACTCGGTCTTGTCTCACCTGAAAGCATGGAT
AATTATTCACATTTCCACGAGCTGAGGGTCACGGAAGAGGAAATAAATGTGCTAAAGCAGGATCTGCAGAATGCATTAGAAGAAAGTGAA
AGAAATAAAGAGAAAGTGAGAGAGTTAGAGGAAAAACTGGTAGAGAGGGAGAAAGGTACAGTGATTAAGCCACCTGTGGAAGAGTACGAG
GAAATGAAAAGTTCATATTGCTCTGTTATTGAGAATATGAATAAGGAGAAAGCATTTTTGTTTGAGAAATACCAAGAAGCCCAAGAAGAA
ATCATGAAATTAAAAGACACACTAAAAAGTCAGATGACACAGGAAGCCAGTGATGAAGCTGAGGACATGAAAGAAGCCATGAATAGGATG
ATAGATGAACTCAATAAACAGGTGAGCGAGCTGTCACAGCTGTACAAAGAAGCCCAGGCTGAGCTGGAGGATTACAGGAAGAGGAAATCT
CTAGAGGATGTCACAGCTGAATATATCCATAAAGCAGAGCATGAGAAACTGATGCAATTGACAAACGTGTCCAGGGCTAAAGCAGAAGAT
GCACTGTCTGAAATGAAGTCTCAGTATTCAAAAGTGTTGAATGAGTTGACCCAGCTCAAACAACTGGTGGATGCACAAAAAGAGAACTCT
GTCTCTATCACAGAACATTTGCAAGTGATAACCACGCTGCGGACTGCAGCAAAAGAGATGGAAGAAAAAATAAGCAATCTTAAGGAACAC
CTTGCAAGCAAGGAAGTGGAAGTAGCAAAGCTGGAGAAACAACTCTTAGAAGAGAAAGCTGCTATGACTGATGCAATGGTACCTCGGTCT
TCCTATGAAAAACTCCAGTCATCCTTAGAGAGTGAAGTGAGTGTGTTGGCATCGAAATTAAAGGAATCTGTGAAAGAGAAAGAGAAGGTC
CATTCAGAGGTTGTCCAGATTAGAAGTGAGGTCTCACAGGTGAAAAGAGAAAAGGAAAATATTCAGACTCTCTTGAAATCCAAAGAGCAA
GAAGTAAATGAACTTCTGCAAAAATTCCAGCAAGCTCAGGAAGAACTTGCAGAAATGAAAAGATACGCTGAGAGCTCTTCAAAACTGGAG
GAAGATAAAGATAAAAAGATAAATGAGATGTCGAAGGAAGTCACCAAATTGAAGGAGGCCTTGAACAGCCTCTCCCAGCTCTCCTACTCA
ACAAGCTCATCCAAAAGGCAGAGTCAGCAGCTGGAGGCGCTGCAGCAGCAAGTCAAACAGCTCCAGAACCAGCTGGCGGAATGCAAGAAA
CAACACCAGGAGGTCATATCAGTTTACAGAATGCATCTTCTGTATGCTGTGCAGGGCCAGATGGATGAAGATGTCCAGAAAGTACTGAAG
CAAATCCTTACCATGTGTAAAAACCAGTCTCAAAAGAAGTAAAGTGGATTCCTTGGCAGGACACTGCCCCTTGTCATCTGTCTT

>2045_2045_12_ADAMTS12-RAI14_ADAMTS12_chr5_33881224_ENST00000504830_RAI14_chr5_34757573_ENST00000515799_length(amino acids)=1131AA_BP=163
MPCAQRSWLANLSVVAQLLNFGALCYGRQPQPGPVRFPDRRQEHFIKGLPEYHVVGPVRVDASGHFLSYGLHYPITSSRRKRDLDGSEDW
VYYRISHEEKDLFFNLTVNQGFLSNSYIMEKRYGNLSHVKMMASSAPLCHLSGTVLQQGTRVGTAALSACHGLTNEWNKNDDRLLQAVEN
GDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSG
KTALHYAAAQGCLQAVQILCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEALIKKGA
DLNLVDSLGYNALHYSKLSENAGIQSLLLSKISQDADLKTPTKPKQHDQVSKISSERSGTPKKRKAPPPPISPTQLSDVSSPRSITSTPL
SGKESVFFAEPPFKAEISSIRENKDRLSDSTTGADSLLDISSEADQQDLLSLLQAKVASLTLHNKELQDKLQAKSPKEAEADLSFDSYHS
TQTDLGPSLGKPGETSPPDSKSSPSVLIHSLGKSTTDNDVRIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNNTEISENSS
DLSQKLKETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNYSHFHELRVTEEEINVLKQDLQNALEESERNKEKVRELEEKLVEREKGTVI
KPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAEL
EDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEE
KISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIRSEVSQVKREKENIQ
TLLKSKEQEVNELLQKFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQ
NQLAECKKQHQEVISVYRMHLLYAVQGQMDEDVQKVLKQILTMCKNQSQKK

--------------------------------------------------------------
>2045_2045_13_ADAMTS12-RAI14_ADAMTS12_chr5_33881224_ENST00000515401_RAI14_chr5_34757573_ENST00000265109_length(transcript)=5421nt_BP=652nt
GCTTAAAAAAGCACAGGGAGATCGCGGGCAGCTTTGCAGTCGCTGCCTTCTCGCGCCTGACCATGCACCCCTGCATCTTCCTGCTGGGCC
ACAGGCGAGCGCTTTATTTCTGGAGCTGAGGGCTAAAACTTTTTTGACTTTTCTTCTCCTCAACATCTGAATCATGCCATGTGCCCAGAG
GAGCTGGCTTGCAAACCTTTCCGTGGTGGCTCAGCTCCTTAACTTTGGGGCGCTTTGCTATGGGAGACAGCCTCAGCCAGGCCCGGTTCG
CTTCCCGGACAGGAGGCAAGAGCATTTTATCAAGGGCCTGCCAGAATACCACGTGGTGGGTCCAGTCCGAGTAGATGCCAGTGGGCATTT
TTTGTCATATGGCTTGCACTATCCCATCACGAGCAGCAGGAGGAAGAGAGATTTGGATGGCTCAGAGGACTGGGTGTACTACAGAATTTC
TCACGAGGAGAAGGACCTGTTTTTTAACTTGACGGTCAATCAAGGATTTCTTTCCAATAGCTACATCATGGAGAAGAGATATGGGAACCT
CTCCCATGTTAAGATGATGGCTTCCTCTGCCCCCCTCTGCCATCTCAGTGGCACGGTTCTACAGCAGGGCACCAGAGTTGGGACGGCAGC
CCTCAGTGCCTGCCATGGACTGACCAATGAGTGGAACAAGAATGATGACCGGCTACTGCAGGCCGTGGAGAATGGAGATGCGGAGAAGGT
GGCCTCACTGCTCGGCAAGAAGGGGGCCAGTGCCACCAAACACGACAGTGAGGGCAAGACCGCTTTCCATCTTGCTGCTGCAAAAGGACA
CGTGGAATGCCTCAGGGTCATGATTACACATGGTGTGGATGTGACAGCCCAAGATACTACCGGACACAGCGCCTTACATCTCGCAGCCAA
GAACAGCCACCATGAATGCATCAGGAAGCTGCTTCAGTCTAAATGCCCAGCCGAAAGTGTCGACAGCTCTGGGAAAACAGCTTTACATTA
TGCAGCGGCTCAGGGCTGCCTTCAAGCTGTGCAGATTCTCTGCGAACACAAGAGCCCCATAAACCTCAAAGATTTGGATGGGAATATACC
GCTGCTTCTTGCTGTACAAAATGGTCACAGTGAGATCTGTCACTTTCTCCTGGATCATGGAGCAGATGTCAATTCCAGGAACAAAAGTGG
AAGAACTGCTCTCATGCTGGCCTGTGAGATTGGCAGCTCTAACGCTGTGGAAGCCTTAATTAAAAAGGGTGCAGACCTAAACCTTGTAGA
TTCTCTTGGATACAATGCCTTACATTATTCCAAACTCTCAGAAAATGCAGGAATTCAAAGCCTTCTATTATCAAAAATCTCTCAGGATGC
TGATTTAAAGACCCCAACAAAACCAAAGCAGCATGACCAAGTCTCTAAAATAAGCTCAGAAAGAAGTGGAACTCCAAAAAAACGCAAAGC
TCCACCACCTCCTATCAGTCCTACCCAGTTGAGTGATGTCTCTTCCCCAAGATCAATAACTTCGACTCCACTATCGGGAAAGGAATCGGT
ATTTTTTGCTGAACCACCCTTCAAGGCTGAGATCAGTTCTATACGAGAAAACAAAGACAGACTAAGTGACAGTACTACAGGTGCTGATAG
CTTATTGGATATAAGTTCTGAAGCTGACCAACAAGATCTTCTCTCTCTATTGCAAGCAAAAGTTGCTTCCCTTACCTTACACAATAAGGA
GTTACAAGATAAATTACAGGCCAAATCACCCAAGGAGGCGGAAGCAGACCTAAGCTTTGACTCATACCATTCCACCCAAACTGACTTGGG
CCCATCCCTGGGAAAACCTGGTGAAACCTCTCCCCCAGACTCCAAATCATCTCCATCTGTCTTAATACATTCTTTAGGTAAATCCACTAC
TGACAATGATGTCAGAATTCAGCAACTGCAAGAGATTTTGCAAGATCTACAGAAGAGATTAGAGAGCTCTGAAGCAGAGAGAAAACAGCT
ACAGGTCGAACTCCAATCCCGAAGGGCAGAACTGGTATGCTTAAACAACACTGAGATTTCAGAGAACAGCTCTGACCTCAGCCAGAAACT
TAAAGAAACTCAGAGCAAATACGAGGAGGCTATGAAAGAAGTCCTTAGTGTGCAGAAGCAGATGAAACTCGGTCTTGTCTCACCTGAAAG
CATGGATAATTATTCACATTTCCACGAGCTGAGGGTCACGGAAGAGGAAATAAATGTGCTAAAGCAGGATCTGCAGAATGCATTAGAAGA
AAGTGAAAGAAATAAAGAGAAAGTGAGAGAGTTAGAGGAAAAACTGGTAGAGAGGGAGAAAGGTACAGTGATTAAGCCACCTGTGGAAGA
GTACGAGGAAATGAAAAGTTCATATTGCTCTGTTATTGAGAATATGAATAAGGAGAAAGCATTTTTGTTTGAGAAATACCAAGAAGCCCA
AGAAGAAATCATGAAATTAAAAGACACACTAAAAAGTCAGATGACACAGGAAGCCAGTGATGAAGCTGAGGACATGAAAGAAGCCATGAA
TAGGATGATAGATGAACTCAATAAACAGGTGAGCGAGCTGTCACAGCTGTACAAAGAAGCCCAGGCTGAGCTGGAGGATTACAGGAAGAG
GAAATCTCTAGAGGATGTCACAGCTGAATATATCCATAAAGCAGAGCATGAGAAACTGATGCAATTGACAAACGTGTCCAGGGCTAAAGC
AGAAGATGCACTGTCTGAAATGAAGTCTCAGTATTCAAAAGTGTTGAATGAGTTGACCCAGCTCAAACAACTGGTGGATGCACAAAAAGA
GAACTCTGTCTCTATCACAGAACATTTGCAAGTGATAACCACGCTGCGGACTGCAGCAAAAGAGATGGAAGAAAAAATAAGCAATCTTAA
GGAACACCTTGCAAGCAAGGAAGTGGAAGTAGCAAAGCTGGAGAAACAACTCTTAGAAGAGAAAGCTGCTATGACTGATGCAATGGTACC
TCGGTCTTCCTATGAAAAACTCCAGTCATCCTTAGAGAGTGAAGTGAGTGTGTTGGCATCGAAATTAAAGGAATCTGTGAAAGAGAAAGA
GAAGGTCCATTCAGAGGTTGTCCAGATTAGAAGTGAGGTCTCACAGGTGAAAAGAGAAAAGGAAAATATTCAGACTCTCTTGAAATCCAA
AGAGCAAGAAGTAAATGAACTTCTGCAAAAATTCCAGCAAGCTCAGGAAGAACTTGCAGAAATGAAAAGATACGCTGAGAGCTCTTCAAA
ACTGGAGGAAGATAAAGATAAAAAGATAAATGAGATGTCGAAGGAAGTCACCAAATTGAAGGAGGCCTTGAACAGCCTCTCCCAGCTCTC
CTACTCAACAAGCTCATCCAAAAGGCAGAGTCAGCAGCTGGAGGCGCTGCAGCAGCAAGTCAAACAGCTCCAGAACCAGCTGGCGGAATG
CAAGAAACAACACCAGGAGGTCATATCAGTTTACAGAATGCATCTTCTGTATGCTGTGCAGGGCCAGATGGATGAAGATGTCCAGAAAGT
ACTGAAGCAAATCCTTACCATGTGTAAAAACCAGTCTCAAAAGAAGTAAAGTGGATTCCTTGGCAGGACACTGCCCCTTGTCATCTGTCT
TTGTGTTAGATCCAGAGTTGTCGGCAGCCGCTGCCATTGTTCTCATTCGTGGTATGCACTGTGGCCTAGCGTAGCTTCTTCCCTTTCCAA
AGGTTTCTGAGGACTTCTCCCAGGAGAAGACTGCCCGCCTCAGAACTGCTTAGAGACTTCAAACCAGCAGAGGTGAAAGTCCCTGTCATC
CCTTCAGATTCCAGAGCTGGGATCAGCCATGCCCAGAGGTCTGGTCCTGATGCTGGCAGGGGGGCCCCCTCCTCCATCCCTGACTGGCTG
AGTGGCTTTATCACCACCGAGTGATGTGCTGAGGCCTCCTGCAGTGAATGCTCCTTCCATTCCTGTACTCGGGCAGTGCCATTCAGCACA
GGAGAGCTCTTTTTGCCTTTGGCTTTCAATTCCAAAACATGATTTAATTTCTAACTAAATTAGTATGGCACTAGTTATGAAGTATCTGCT
TAAAACCCTTCATCATGATATCCTGTGGATTTAAAAACTCTAATTCCATGTTTTCTTCCCATCTGCCTTATATATCTCATCACCCTGCTT
ATCAATATTCAGTTTGATGAGCACTATTAACTAAAATATGAAACTTAAAAACAAAAGCAAGTTGTCCTTAAAAGTTCTTTTTTTAAGTAA
ATTGTTGACATACTGCAAATTTTCTATGCAAACTTGCCTCCTGCTGTTATCTGTGAAGCTCAGGAAATCCAAACATTTGTGTTTCAACAA
GGGACAGTAAACTGTGTGTTTACAGCCAAAAGAAATGCCTCATAGTTCTTAACCTCAACTTTTGTAGAAGTATTTTTTTCTCTGTAATAT
TTTTATTGGCTCATAAAGATGTTTTCATATCTGAACTCCTAAATAAGTGAAATTACAGTAGATTATATTAACAAAATACTTTTTAGGTAG
CCATGCTTGAGACTTTTTAAAAATATAACTTTTTCCTTAAAGTTTTCAGCTATAGCAAAAGGTAGTTATGTATGCCAGACCTAATATGAG
CTGCCACCAACACCCCTAGAACTTTCAGCCATGGTGTCTTCAGAATTGTAGCGCATTTCTGAATCTAGCAAATCCTCCTTTTACCCGTTG
AATGTTTTGAATGCCCTGACTCTACCAGCGCCCATAAATGATCTCTAGAAGGACTGTTAGTACCAATCTGTTTTTCAACTTTGAAGCTAA
AAACCCTGATATGGTAATATTATGGTGCATAGCAGAGGTCTCGGAAAAAAAATATTTCTGTTCACTTTACTTTCAGGTTAAAAATGTTTC
TAACACGCTTGCAACTTCCCTTATGGCATTAATCTTGTTGAGGGAGAGAGACAGAATCCTGGACTCTCCAAAGTATTTAACTGAAAGTAG
GGCCTGCTCTGACAGGGCCCATGTCCCACAAGGCTGCTTGGCCTCAGTGGGTGCTTGGCTGTGCTGGATGATATGTTGATCTGTATTGGA
TAAGGACCAATGACAGCAAAGCAAAAATGGCTTTAAAGCTTGGTGTTACTTTTCTTAAGTTGTTTAATTATAGTTAAGCAATTTCAAAAA
TGCTCCAAAGAAATGTGAAAGGACCTTTTGTCACAGCACTTCAGAAAATACACAACAGCCCCTTCTGCCCCCGCACAGAAATGCTGCAGA
GTATATAAAACTTGAGACATTTTTGTAGGATGCCTGACGAGGTGTAGCCTTTTATCTTGTTTCCGGATGCATATTTATTACGAGTACTCT
GGTTAAATATTGAAAAGTTATATGCTGTAGTTTTTAGTATTTTGTCTTTGTAATTTACAGAAGTTATTGGAGAAAATAAACTTGTTTCAT
TTTGCATTTCTGGTGTTGATT

>2045_2045_13_ADAMTS12-RAI14_ADAMTS12_chr5_33881224_ENST00000515401_RAI14_chr5_34757573_ENST00000265109_length(amino acids)=1131AA_BP=163
MPCAQRSWLANLSVVAQLLNFGALCYGRQPQPGPVRFPDRRQEHFIKGLPEYHVVGPVRVDASGHFLSYGLHYPITSSRRKRDLDGSEDW
VYYRISHEEKDLFFNLTVNQGFLSNSYIMEKRYGNLSHVKMMASSAPLCHLSGTVLQQGTRVGTAALSACHGLTNEWNKNDDRLLQAVEN
GDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSG
KTALHYAAAQGCLQAVQILCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEALIKKGA
DLNLVDSLGYNALHYSKLSENAGIQSLLLSKISQDADLKTPTKPKQHDQVSKISSERSGTPKKRKAPPPPISPTQLSDVSSPRSITSTPL
SGKESVFFAEPPFKAEISSIRENKDRLSDSTTGADSLLDISSEADQQDLLSLLQAKVASLTLHNKELQDKLQAKSPKEAEADLSFDSYHS
TQTDLGPSLGKPGETSPPDSKSSPSVLIHSLGKSTTDNDVRIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNNTEISENSS
DLSQKLKETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNYSHFHELRVTEEEINVLKQDLQNALEESERNKEKVRELEEKLVEREKGTVI
KPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAEL
EDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEE
KISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIRSEVSQVKREKENIQ
TLLKSKEQEVNELLQKFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQ
NQLAECKKQHQEVISVYRMHLLYAVQGQMDEDVQKVLKQILTMCKNQSQKK

--------------------------------------------------------------
>2045_2045_14_ADAMTS12-RAI14_ADAMTS12_chr5_33881224_ENST00000515401_RAI14_chr5_34757573_ENST00000428746_length(transcript)=5405nt_BP=652nt
GCTTAAAAAAGCACAGGGAGATCGCGGGCAGCTTTGCAGTCGCTGCCTTCTCGCGCCTGACCATGCACCCCTGCATCTTCCTGCTGGGCC
ACAGGCGAGCGCTTTATTTCTGGAGCTGAGGGCTAAAACTTTTTTGACTTTTCTTCTCCTCAACATCTGAATCATGCCATGTGCCCAGAG
GAGCTGGCTTGCAAACCTTTCCGTGGTGGCTCAGCTCCTTAACTTTGGGGCGCTTTGCTATGGGAGACAGCCTCAGCCAGGCCCGGTTCG
CTTCCCGGACAGGAGGCAAGAGCATTTTATCAAGGGCCTGCCAGAATACCACGTGGTGGGTCCAGTCCGAGTAGATGCCAGTGGGCATTT
TTTGTCATATGGCTTGCACTATCCCATCACGAGCAGCAGGAGGAAGAGAGATTTGGATGGCTCAGAGGACTGGGTGTACTACAGAATTTC
TCACGAGGAGAAGGACCTGTTTTTTAACTTGACGGTCAATCAAGGATTTCTTTCCAATAGCTACATCATGGAGAAGAGATATGGGAACCT
CTCCCATGTTAAGATGATGGCTTCCTCTGCCCCCCTCTGCCATCTCAGTGGCACGGTTCTACAGCAGGGCACCAGAGTTGGGACGGCAGC
CCTCAGTGCCTGCCATGGACTGACCAATGAGTGGAACAAGAATGATGACCGGCTACTGCAGGCCGTGGAGAATGGAGATGCGGAGAAGGT
GGCCTCACTGCTCGGCAAGAAGGGGGCCAGTGCCACCAAACACGACAGTGAGGGCAAGACCGCTTTCCATCTTGCTGCTGCAAAAGGACA
CGTGGAATGCCTCAGGGTCATGATTACACATGGTGTGGATGTGACAGCCCAAGATACTACCGGACACAGCGCCTTACATCTCGCAGCCAA
GAACAGCCACCATGAATGCATCAGGAAGCTGCTTCAGTCTAAATGCCCAGCCGAAAGTGTCGACAGCTCTGGGAAAACAGCTTTACATTA
TGCAGCGGCTCAGGGCTGCCTTCAAGCTGTGCAGATTCTCTGCGAACACAAGAGCCCCATAAACCTCAAAGATTTGGATGGGAATATACC
GCTGCTTCTTGCTGTACAAAATGGTCACAGTGAGATCTGTCACTTTCTCCTGGATCATGGAGCAGATGTCAATTCCAGGAACAAAAGTGG
AAGAACTGCTCTCATGCTGGCCTGTGAGATTGGCAGCTCTAACGCTGTGGAAGCCTTAATTAAAAAGGGTGCAGACCTAAACCTTGTAGA
TTCTCTTGGATACAATGCCTTACATTATTCCAAACTCTCAGAAAATGCAGGAATTCAAAGCCTTCTATTATCAAAAATCTCTCAGGATGC
TGATTTAAAGACCCCAACAAAACCAAAGCAGCATGACCAAGTCTCTAAAATAAGCTCAGAAAGAAGTGGAACTCCAAAAAAACGCAAAGC
TCCACCACCTCCTATCAGTCCTACCCAGTTGAGTGATGTCTCTTCCCCAAGATCAATAACTTCGACTCCACTATCGGGAAAGGAATCGGT
ATTTTTTGCTGAACCACCCTTCAAGGCTGAGATCAGTTCTATACGAGAAAACAAAGACAGACTAAGTGACAGTACTACAGGTGCTGATAG
CTTATTGGATATAAGTTCTGAAGCTGACCAACAAGATCTTCTCTCTCTATTGCAAGCAAAAGTTGCTTCCCTTACCTTACACAATAAGGA
GTTACAAGATAAATTACAGGCCAAATCACCCAAGGAGGCGGAAGCAGACCTAAGCTTTGACTCATACCATTCCACCCAAACTGACTTGGG
CCCATCCCTGGGAAAACCTGGTGAAACCTCTCCCCCAGACTCCAAATCATCTCCATCTGTCTTAATACATTCTTTAGGTAAATCCACTAC
TGACAATGATGTCAGAATTCAGCAACTGCAAGAGATTTTGCAAGATCTACAGAAGAGATTAGAGAGCTCTGAAGCAGAGAGAAAACAGCT
ACAGGTCGAACTCCAATCCCGAAGGGCAGAACTGGTATGCTTAAACAACACTGAGATTTCAGAGAACAGCTCTGACCTCAGCCAGAAACT
TAAAGAAACTCAGAGCAAATACGAGGAGGCTATGAAAGAAGTCCTTAGTGTGCAGAAGCAGATGAAACTCGGTCTTGTCTCACCTGAAAG
CATGGATAATTATTCACATTTCCACGAGCTGAGGGTCACGGAAGAGGAAATAAATGTGCTAAAGCAGGATCTGCAGAATGCATTAGAAGA
AAGTGAAAGAAATAAAGAGAAAGTGAGAGAGTTAGAGGAAAAACTGGTAGAGAGGGAGAAAGGTACAGTGATTAAGCCACCTGTGGAAGA
GTACGAGGAAATGAAAAGTTCATATTGCTCTGTTATTGAGAATATGAATAAGGAGAAAGCATTTTTGTTTGAGAAATACCAAGAAGCCCA
AGAAGAAATCATGAAATTAAAAGACACACTAAAAAGTCAGATGACACAGGAAGCCAGTGATGAAGCTGAGGACATGAAAGAAGCCATGAA
TAGGATGATAGATGAACTCAATAAACAGGTGAGCGAGCTGTCACAGCTGTACAAAGAAGCCCAGGCTGAGCTGGAGGATTACAGGAAGAG
GAAATCTCTAGAGGATGTCACAGCTGAATATATCCATAAAGCAGAGCATGAGAAACTGATGCAATTGACAAACGTGTCCAGGGCTAAAGC
AGAAGATGCACTGTCTGAAATGAAGTCTCAGTATTCAAAAGTGTTGAATGAGTTGACCCAGCTCAAACAACTGGTGGATGCACAAAAAGA
GAACTCTGTCTCTATCACAGAACATTTGCAAGTGATAACCACGCTGCGGACTGCAGCAAAAGAGATGGAAGAAAAAATAAGCAATCTTAA
GGAACACCTTGCAAGCAAGGAAGTGGAAGTAGCAAAGCTGGAGAAACAACTCTTAGAAGAGAAAGCTGCTATGACTGATGCAATGGTACC
TCGGTCTTCCTATGAAAAACTCCAGTCATCCTTAGAGAGTGAAGTGAGTGTGTTGGCATCGAAATTAAAGGAATCTGTGAAAGAGAAAGA
GAAGGTCCATTCAGAGGTTGTCCAGATTAGAAGTGAGGTCTCACAGGTGAAAAGAGAAAAGGAAAATATTCAGACTCTCTTGAAATCCAA
AGAGCAAGAAGTAAATGAACTTCTGCAAAAATTCCAGCAAGCTCAGGAAGAACTTGCAGAAATGAAAAGATACGCTGAGAGCTCTTCAAA
ACTGGAGGAAGATAAAGATAAAAAGATAAATGAGATGTCGAAGGAAGTCACCAAATTGAAGGAGGCCTTGAACAGCCTCTCCCAGCTCTC
CTACTCAACAAGCTCATCCAAAAGGCAGAGTCAGCAGCTGGAGGCGCTGCAGCAGCAAGTCAAACAGCTCCAGAACCAGCTGGCGGAATG
CAAGAAACAACACCAGGAGGTCATATCAGTTTACAGAATGCATCTTCTGTATGCTGTGCAGGGCCAGATGGATGAAGATGTCCAGAAAGT
ACTGAAGCAAATCCTTACCATGTGTAAAAACCAGTCTCAAAAGAAGTAAAGTGGATTCCTTGGCAGGACACTGCCCCTTGTCATCTGTCT
TTGTGTTAGATCCAGAGTTGTCGGCAGCCGCTGCCATTGTTCTCATTCGTGGTATGCACTGTGGCCTAGCGTAGCTTCTTCCCTTTCCAA
AGGTTTCTGAGGACTTCTCCCAGGAGAAGACTGCCCGCCTCAGAACTGCTTAGAGACTTCAAACCAGCAGAGGTGAAAGTCCCTGTCATC
CCTTCAGATTCCAGAGCTGGGATCAGCCATGCCCAGAGGTCTGGTCCTGATGCTGGCAGGGGGGCCCCCTCCTCCATCCCTGACTGGCTG
AGTGGCTTTATCACCACCGAGTGATGTGCTGAGGCCTCCTGCAGTGAATGCTCCTTCCATTCCTGTACTCGGGCAGTGCCATTCAGCACA
GGAGAGCTCTTTTTGCCTTTGGCTTTCAATTCCAAAACATGATTTAATTTCTAACTAAATTAGTATGGCACTAGTTATGAAGTATCTGCT
TAAAACCCTTCATCATGATATCCTGTGGATTTAAAAACTCTAATTCCATGTTTTCTTCCCATCTGCCTTATATATCTCATCACCCTGCTT
ATCAATATTCAGTTTGATGAGCACTATTAACTAAAATATGAAACTTAAAAACAAAAGCAAGTTGTCCTTAAAAGTTCTTTTTTTAAGTAA
ATTGTTGACATACTGCAAATTTTCTATGCAAACTTGCCTCCTGCTGTTATCTGTGAAGCTCAGGAAATCCAAACATTTGTGTTTCAACAA
GGGACAGTAAACTGTGTGTTTACAGCCAAAAGAAATGCCTCATAGTTCTTAACCTCAACTTTTGTAGAAGTATTTTTTTCTCTGTAATAT
TTTTATTGGCTCATAAAGATGTTTTCATATCTGAACTCCTAAATAAGTGAAATTACAGTAGATTATATTAACAAAATACTTTTTAGGTAG
CCATGCTTGAGACTTTTTAAAAATATAACTTTTTCCTTAAAGTTTTCAGCTATAGCAAAAGGTAGTTATGTATGCCAGACCTAATATGAG
CTGCCACCAACACCCCTAGAACTTTCAGCCATGGTGTCTTCAGAATTGTAGCGCATTTCTGAATCTAGCAAATCCTCCTTTTACCCGTTG
AATGTTTTGAATGCCCTGACTCTACCAGCGCCCATAAATGATCTCTAGAAGGACTGTTAGTACCAATCTGTTTTTCAACTTTGAAGCTAA
AAACCCTGATATGGTAATATTATGGTGCATAGCAGAGGTCTCGGAAAAAAAATATTTCTGTTCACTTTACTTTCAGGTTAAAAATGTTTC
TAACACGCTTGCAACTTCCCTTATGGCATTAATCTTGTTGAGGGAGAGAGACAGAATCCTGGACTCTCCAAAGTATTTAACTGAAAGTAG
GGCCTGCTCTGACAGGGCCCATGTCCCACAAGGCTGCTTGGCCTCAGTGGGTGCTTGGCTGTGCTGGATGATATGTTGATCTGTATTGGA
TAAGGACCAATGACAGCAAAGCAAAAATGGCTTTAAAGCTTGGTGTTACTTTTCTTAAGTTGTTTAATTATAGTTAAGCAATTTCAAAAA
TGCTCCAAAGAAATGTGAAAGGACCTTTTGTCACAGCACTTCAGAAAATACACAACAGCCCCTTCTGCCCCCGCACAGAAATGCTGCAGA
GTATATAAAACTTGAGACATTTTTGTAGGATGCCTGACGAGGTGTAGCCTTTTATCTTGTTTCCGGATGCATATTTATTACGAGTACTCT
GGTTAAATATTGAAAAGTTATATGCTGTAGTTTTTAGTATTTTGTCTTTGTAATTTACAGAAGTTATTGGAGAAAATAAACTTGTTTCAT
TTTGC

>2045_2045_14_ADAMTS12-RAI14_ADAMTS12_chr5_33881224_ENST00000515401_RAI14_chr5_34757573_ENST00000428746_length(amino acids)=1131AA_BP=163
MPCAQRSWLANLSVVAQLLNFGALCYGRQPQPGPVRFPDRRQEHFIKGLPEYHVVGPVRVDASGHFLSYGLHYPITSSRRKRDLDGSEDW
VYYRISHEEKDLFFNLTVNQGFLSNSYIMEKRYGNLSHVKMMASSAPLCHLSGTVLQQGTRVGTAALSACHGLTNEWNKNDDRLLQAVEN
GDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSG
KTALHYAAAQGCLQAVQILCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEALIKKGA
DLNLVDSLGYNALHYSKLSENAGIQSLLLSKISQDADLKTPTKPKQHDQVSKISSERSGTPKKRKAPPPPISPTQLSDVSSPRSITSTPL
SGKESVFFAEPPFKAEISSIRENKDRLSDSTTGADSLLDISSEADQQDLLSLLQAKVASLTLHNKELQDKLQAKSPKEAEADLSFDSYHS
TQTDLGPSLGKPGETSPPDSKSSPSVLIHSLGKSTTDNDVRIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNNTEISENSS
DLSQKLKETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNYSHFHELRVTEEEINVLKQDLQNALEESERNKEKVRELEEKLVEREKGTVI
KPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAEL
EDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEE
KISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIRSEVSQVKREKENIQ
TLLKSKEQEVNELLQKFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQ
NQLAECKKQHQEVISVYRMHLLYAVQGQMDEDVQKVLKQILTMCKNQSQKK

--------------------------------------------------------------
>2045_2045_15_ADAMTS12-RAI14_ADAMTS12_chr5_33881224_ENST00000515401_RAI14_chr5_34757573_ENST00000503673_length(transcript)=3599nt_BP=652nt
GCTTAAAAAAGCACAGGGAGATCGCGGGCAGCTTTGCAGTCGCTGCCTTCTCGCGCCTGACCATGCACCCCTGCATCTTCCTGCTGGGCC
ACAGGCGAGCGCTTTATTTCTGGAGCTGAGGGCTAAAACTTTTTTGACTTTTCTTCTCCTCAACATCTGAATCATGCCATGTGCCCAGAG
GAGCTGGCTTGCAAACCTTTCCGTGGTGGCTCAGCTCCTTAACTTTGGGGCGCTTTGCTATGGGAGACAGCCTCAGCCAGGCCCGGTTCG
CTTCCCGGACAGGAGGCAAGAGCATTTTATCAAGGGCCTGCCAGAATACCACGTGGTGGGTCCAGTCCGAGTAGATGCCAGTGGGCATTT
TTTGTCATATGGCTTGCACTATCCCATCACGAGCAGCAGGAGGAAGAGAGATTTGGATGGCTCAGAGGACTGGGTGTACTACAGAATTTC
TCACGAGGAGAAGGACCTGTTTTTTAACTTGACGGTCAATCAAGGATTTCTTTCCAATAGCTACATCATGGAGAAGAGATATGGGAACCT
CTCCCATGTTAAGATGATGGCTTCCTCTGCCCCCCTCTGCCATCTCAGTGGCACGGTTCTACAGCAGGGCACCAGAGTTGGGACGGCAGC
CCTCAGTGCCTGCCATGGACTGACCAATGAGTGGAACAAGAATGATGACCGGCTACTGCAGGCCGTGGAGAATGGAGATGCGGAGAAGGT
GGCCTCACTGCTCGGCAAGAAGGGGGCCAGTGCCACCAAACACGACAGTGAGGGCAAGACCGCTTTCCATCTTGCTGCTGCAAAAGGACA
CGTGGAATGCCTCAGGGTCATGATTACACATGGTGTGGATGTGACAGCCCAAGATACTACCGGACACAGCGCCTTACATCTCGCAGCCAA
GAACAGCCACCATGAATGCATCAGGAAGCTGCTTCAGTCTAAATGCCCAGCCGAAAGTGTCGACAGCTCTGGGAAAACAGCTTTACATTA
TGCAGCGGCTCAGGGCTGCCTTCAAGCTGTGCAGATTCTCTGCGAACACAAGAGCCCCATAAACCTCAAAGATTTGGATGGGAATATACC
GCTGCTTCTTGCTGTACAAAATGGTCACAGTGAGATCTGTCACTTTCTCCTGGATCATGGAGCAGATGTCAATTCCAGGAACAAAAGTGG
AAGAACTGCTCTCATGCTGGCCTGTGAGATTGGCAGCTCTAACGCTGTGGAAGCCTTAATTAAAAAGGGTGCAGACCTAAACCTTGTAGA
TTCTCTTGGATACAATGCCTTACATTATTCCAAACTCTCAGAAAATGCAGGAATTCAAAGCCTTCTATTATCAAAAATCTCTCAGGATGC
TGATTTAAAGACCCCAACAAAACCAAAGCAGCATGACCAAGTCTCTAAAATAAGCTCAGAAAGAAGTGGAACTCCAAAAAAACGCAAAGC
TCCACCACCTCCTATCAGTCCTACCCAGTTGAGTGATGTCTCTTCCCCAAGATCAATAACTTCGACTCCACTATCGGGAAAGGAATCGGT
ATTTTTTGCTGAACCACCCTTCAAGGCTGAGATCAGTTCTATACGAGAAAACAAAGACAGACTAAGTGACAGTACTACAGGTGCTGATAG
CTTATTGGATATAAGTTCTGAAGCTGACCAACAAGATCTTCTCTCTCTATTGCAAGCAAAAGTTGCTTCCCTTACCTTACACAATAAGGA
GTTACAAGATAAATTACAGGCCAAATCACCCAAGGAGGCGGAAGCAGACCTAAGCTTTGACTCATACCATTCCACCCAAACTGACTTGGG
CCCATCCCTGGGAAAACCTGGTGAAACCTCTCCCCCAGACTCCAAATCATCTCCATCTGTCTTAATACATTCTTTAGGTAAATCCACTAC
TGACAATGATGTCAGAATTCAGCAACTGCAAGAGATTTTGCAAGATCTACAGAAGAGATTAGAGAGCTCTGAAGCAGAGAGAAAACAGCT
ACAGGTCGAACTCCAATCCCGAAGGGCAGAACTGGTATGCTTAAACAACACTGAGATTTCAGAGAACAGCTCTGACCTCAGCCAGAAACT
TAAAGAAACTCAGAGCAAATACGAGGAGGCTATGAAAGAAGTCCTTAGTGTGCAGAAGCAGATGAAACTCGGTCTTGTCTCACCTGAAAG
CATGGATAATTATTCACATTTCCACGAGCTGAGGGTCACGGAAGAGGAAATAAATGTGCTAAAGCAGGATCTGCAGAATGCATTAGAAGA
AAGTGAAAGAAATAAAGAGAAAGTGAGAGAGTTAGAGGAAAAACTGGTAGAGAGGGAGAAAGGTACAGTGATTAAGCCACCTGTGGAAGA
GTACGAGGAAATGAAAAGTTCATATTGCTCTGTTATTGAGAATATGAATAAGGAGAAAGCATTTTTGTTTGAGAAATACCAAGAAGCCCA
AGAAGAAATCATGAAATTAAAAGACACACTAAAAAGTCAGATGACACAGGAAGCCAGTGATGAAGCTGAGGACATGAAAGAAGCCATGAA
TAGGATGATAGATGAACTCAATAAACAGGTGAGCGAGCTGTCACAGCTGTACAAAGAAGCCCAGGCTGAGCTGGAGGATTACAGGAAGAG
GAAATCTCTAGAGGATGTCACAGCTGAATATATCCATAAAGCAGAGCATGAGAAACTGATGCAATTGACAAACGTGTCCAGGGCTAAAGC
AGAAGATGCACTGTCTGAAATGAAGTCTCAGTATTCAAAAGTGTTGAATGAGTTGACCCAGCTCAAACAACTGGTGGATGCACAAAAAGA
GAACTCTGTCTCTATCACAGAACATTTGCAAGTGATAACCACGCTGCGGACTGCAGCAAAAGAGATGGAAGAAAAAATAAGCAATCTTAA
GGAACACCTTGCAAGCAAGGAAGTGGAAGTAGCAAAGCTGGAGAAACAACTCTTAGAAGAGAAAGCTGCTATGACTGATGCAATGGTACC
TCGGTCTTCCTATGAAAAACTCCAGTCATCCTTAGAGAGTGAAGTGAGTGTGTTGGCATCGAAATTAAAGGAATCTGTGAAAGAGAAAGA
GAAGGTCCATTCAGAGGTTGTCCAGATTAGAAGTGAGGTCTCACAGGTGAAAAGAGAAAAGGAAAATATTCAGACTCTCTTGAAATCCAA
AGAGCAAGAAGTAAATGAACTTCTGCAAAAATTCCAGCAAGCTCAGGAAGAACTTGCAGAAATGAAAAGATACGCTGAGAGCTCTTCAAA
ACTGGAGGAAGATAAAGATAAAAAGATAAATGAGATGTCGAAGGAAGTCACCAAATTGAAGGAGGCCTTGAACAGCCTCTCCCAGCTCTC
CTACTCAACAAGCTCATCCAAAAGGCAGAGTCAGCAGCTGGAGGCGCTGCAGCAGCAAGTCAAACAGCTCCAGAACCAGCTGGCGGAATG
CAAGAAACAACACCAGGAGGTCATATCAGTTTACAGAATGCATCTTCTGTATGCTGTGCAGGGCCAGATGGATGAAGATGTCCAGAAAGT
ACTGAAGCAAATCCTTACCATGTGTAAAAACCAGTCTCAAAAGAAGTAAAGTGGATTCCTTGGCAGGACACTGCCCCTTGTCATCTGTC

>2045_2045_15_ADAMTS12-RAI14_ADAMTS12_chr5_33881224_ENST00000515401_RAI14_chr5_34757573_ENST00000503673_length(amino acids)=1131AA_BP=163
MPCAQRSWLANLSVVAQLLNFGALCYGRQPQPGPVRFPDRRQEHFIKGLPEYHVVGPVRVDASGHFLSYGLHYPITSSRRKRDLDGSEDW
VYYRISHEEKDLFFNLTVNQGFLSNSYIMEKRYGNLSHVKMMASSAPLCHLSGTVLQQGTRVGTAALSACHGLTNEWNKNDDRLLQAVEN
GDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSG
KTALHYAAAQGCLQAVQILCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEALIKKGA
DLNLVDSLGYNALHYSKLSENAGIQSLLLSKISQDADLKTPTKPKQHDQVSKISSERSGTPKKRKAPPPPISPTQLSDVSSPRSITSTPL
SGKESVFFAEPPFKAEISSIRENKDRLSDSTTGADSLLDISSEADQQDLLSLLQAKVASLTLHNKELQDKLQAKSPKEAEADLSFDSYHS
TQTDLGPSLGKPGETSPPDSKSSPSVLIHSLGKSTTDNDVRIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNNTEISENSS
DLSQKLKETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNYSHFHELRVTEEEINVLKQDLQNALEESERNKEKVRELEEKLVEREKGTVI
KPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAEL
EDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEE
KISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIRSEVSQVKREKENIQ
TLLKSKEQEVNELLQKFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQ
NQLAECKKQHQEVISVYRMHLLYAVQGQMDEDVQKVLKQILTMCKNQSQKK

--------------------------------------------------------------
>2045_2045_16_ADAMTS12-RAI14_ADAMTS12_chr5_33881224_ENST00000515401_RAI14_chr5_34757573_ENST00000506376_length(transcript)=3579nt_BP=652nt
GCTTAAAAAAGCACAGGGAGATCGCGGGCAGCTTTGCAGTCGCTGCCTTCTCGCGCCTGACCATGCACCCCTGCATCTTCCTGCTGGGCC
ACAGGCGAGCGCTTTATTTCTGGAGCTGAGGGCTAAAACTTTTTTGACTTTTCTTCTCCTCAACATCTGAATCATGCCATGTGCCCAGAG
GAGCTGGCTTGCAAACCTTTCCGTGGTGGCTCAGCTCCTTAACTTTGGGGCGCTTTGCTATGGGAGACAGCCTCAGCCAGGCCCGGTTCG
CTTCCCGGACAGGAGGCAAGAGCATTTTATCAAGGGCCTGCCAGAATACCACGTGGTGGGTCCAGTCCGAGTAGATGCCAGTGGGCATTT
TTTGTCATATGGCTTGCACTATCCCATCACGAGCAGCAGGAGGAAGAGAGATTTGGATGGCTCAGAGGACTGGGTGTACTACAGAATTTC
TCACGAGGAGAAGGACCTGTTTTTTAACTTGACGGTCAATCAAGGATTTCTTTCCAATAGCTACATCATGGAGAAGAGATATGGGAACCT
CTCCCATGTTAAGATGATGGCTTCCTCTGCCCCCCTCTGCCATCTCAGTGGCACGGTTCTACAGCAGGGCACCAGAGTTGGGACGGCAGC
CCTCAGTGCCTGCCATGGACTGACCAATGAGTGGAACAAGAATGATGACCGGCTACTGCAGGCCGTGGAGAATGGAGATGCGGAGAAGGT
GGCCTCACTGCTCGGCAAGAAGGGGGCCAGTGCCACCAAACACGACAGTGAGGGCAAGACCGCTTTCCATCTTGCTGCTGCAAAAGGACA
CGTGGAATGCCTCAGGGTCATGATTACACATGGTGTGGATGTGACAGCCCAAGATACTACCGGACACAGCGCCTTACATCTCGCAGCCAA
GAACAGCCACCATGAATGCATCAGGAAGCTGCTTCAGTCTAAATGCCCAGCCGAAAGTGTCGACAGCTCTGGGAAAACAGCTTTACATTA
TGCAGCGGCTCAGGGCTGCCTTCAAGCTGTGCAGATTCTCTGCGAACACAAGAGCCCCATAAACCTCAAAGATTTGGATGGGAATATACC
GCTGCTTCTTGCTGTACAAAATGGTCACAGTGAGATCTGTCACTTTCTCCTGGATCATGGAGCAGATGTCAATTCCAGGAACAAAAGTGG
AAGAACTGCTCTCATGCTGGCCTGTGAGATTGGCAGCTCTAACGCTGTGGAAGCCTTAATTAAAAAGGGTGCAGACCTAAACCTTGTAGA
TTCTCTTGGATACAATGCCTTACATTATTCCAAACTCTCAGAAAATGCAGGAATTCAAAGCCTTCTATTATCAAAAATCTCTCAGGATGC
TGATTTAAAGACCCCAACAAAACCAAAGCAGCATGACCAAGTCTCTAAAATAAGCTCAGAAAGAAGTGGAACTCCAAAAAAACGCAAAGC
TCCACCACCTCCTATCAGTCCTACCCAGTTGAGTGATGTCTCTTCCCCAAGATCAATAACTTCGACTCCACTATCGGGAAAGGAATCGGT
ATTTTTTGCTGAACCACCCTTCAAGGCTGAGATCAGTTCTATACGAGAAAACAAAGACAGACTAAGTGACAGTACTACAGGTGCTGATAG
CTTATTGGATATAAGTTCTGAAGCTGACCAACAAGATCTTCTCTCTCTATTGCAAGCAAAAGTTGCTTCCCTTACCTTACACAATAAGGA
GTTACAAGATAAATTACAGGCCAAATCACCCAAGGAGGCGGAAGCAGACCTAAGCTTTGACTCATACCATTCCACCCAAACTGACTTGGG
CCCATCCCTGGGAAAACCTGGTGAAACCTCTCCCCCAGACTCCAAATCATCTCCATCTGTCTTAATACATTCTTTAGGTAAATCCACTAC
TGACAATGATGTCAGAATTCAGCAACTGCAAGAGATTTTGCAAGATCTACAGAAGAGATTAGAGAGCTCTGAAGCAGAGAGAAAACAGCT
ACAGGTCGAACTCCAATCCCGAAGGGCAGAACTGGTATGCTTAAACAACACTGAGATTTCAGAGAACAGCTCTGACCTCAGCCAGAAACT
TAAAGAAACTCAGAGCAAATACGAGGAGGCTATGAAAGAAGTCCTTAGTGTGCAGAAGCAGATGAAACTCGGTCTTGTCTCACCTGAAAG
CATGGATAATTATTCACATTTCCACGAGCTGAGGGTCACGGAAGAGGAAATAAATGTGCTAAAGCAGGATCTGCAGAATGCATTAGAAGA
AAGTGAAAGAAATAAAGAGAAAGTGAGAGAGTTAGAGGAAAAACTGGTAGAGAGGGAGAAAGGTACAGTGATTAAGCCACCTGTGGAAGA
GTACGAGGAAATGAAAAGTTCATATTGCTCTGTTATTGAGAATATGAATAAGGAGAAAGCATTTTTGTTTGAGAAATACCAAGAAGCCCA
AGAAGAAATCATGAAATTAAAAGACACACTAAAAAGTCAGATGACACAGGAAGCCAGTGATGAAGCTGAGGACATGAAAGAAGCCATGAA
TAGGATGATAGATGAACTCAATAAACAGGTGAGCGAGCTGTCACAGCTGTACAAAGAAGCCCAGGCTGAGCTGGAGGATTACAGGAAGAG
GAAATCTCTAGAGGATGTCACAGCTGAATATATCCATAAAGCAGAGCATGAGAAACTGATGCAATTGACAAACGTGTCCAGGGCTAAAGC
AGAAGATGCACTGTCTGAAATGAAGTCTCAGTATTCAAAAGTGTTGAATGAGTTGACCCAGCTCAAACAACTGGTGGATGCACAAAAAGA
GAACTCTGTCTCTATCACAGAACATTTGCAAGTGATAACCACGCTGCGGACTGCAGCAAAAGAGATGGAAGAAAAAATAAGCAATCTTAA
GGAACACCTTGCAAGCAAGGAAGTGGAAGTAGCAAAGCTGGAGAAACAACTCTTAGAAGAGAAAGCTGCTATGACTGATGCAATGGTACC
TCGGTCTTCCTATGAAAAACTCCAGTCATCCTTAGAGAGTGAAGTGAGTGTGTTGGCATCGAAATTAAAGGAATCTGTGAAAGAGAAAGA
GAAGGTCCATTCAGAGGTTGTCCAGATTAGAAGTGAGGTCTCACAGGTGAAAAGAGAAAAGGAAAATATTCAGACTCTCTTGAAATCCAA
AGAGCAAGAAGTAAATGAACTTCTGCAAAAATTCCAGCAAGCTCAGGAAGAACTTGCAGAAATGAAAAGATACGCTGAGAGCTCTTCAAA
ACTGGAGGAAGATAAAGATAAAAAGATAAATGAGATGTCGAAGGAAGTCACCAAATTGAAGGAGGCCTTGAACAGCCTCTCCCAGCTCTC
CTACTCAACAAGCTCATCCAAAAGGCAGAGTCAGCAGCTGGAGGCGCTGCAGCAGCAAGTCAAACAGCTCCAGAACCAGCTGGCGGAATG
CAAGAAACAACACCAGGAGGTCATATCAGTTTACAGAATGCATCTTCTGTATGCTGTGCAGGGCCAGATGGATGAAGATGTCCAGAAAGT
ACTGAAGCAAATCCTTACCATGTGTAAAAACCAGTCTCAAAAGAAGTAAAGTGGATTCCTTGGCAGGAC

>2045_2045_16_ADAMTS12-RAI14_ADAMTS12_chr5_33881224_ENST00000515401_RAI14_chr5_34757573_ENST00000506376_length(amino acids)=1131AA_BP=163
MPCAQRSWLANLSVVAQLLNFGALCYGRQPQPGPVRFPDRRQEHFIKGLPEYHVVGPVRVDASGHFLSYGLHYPITSSRRKRDLDGSEDW
VYYRISHEEKDLFFNLTVNQGFLSNSYIMEKRYGNLSHVKMMASSAPLCHLSGTVLQQGTRVGTAALSACHGLTNEWNKNDDRLLQAVEN
GDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSG
KTALHYAAAQGCLQAVQILCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEALIKKGA
DLNLVDSLGYNALHYSKLSENAGIQSLLLSKISQDADLKTPTKPKQHDQVSKISSERSGTPKKRKAPPPPISPTQLSDVSSPRSITSTPL
SGKESVFFAEPPFKAEISSIRENKDRLSDSTTGADSLLDISSEADQQDLLSLLQAKVASLTLHNKELQDKLQAKSPKEAEADLSFDSYHS
TQTDLGPSLGKPGETSPPDSKSSPSVLIHSLGKSTTDNDVRIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNNTEISENSS
DLSQKLKETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNYSHFHELRVTEEEINVLKQDLQNALEESERNKEKVRELEEKLVEREKGTVI
KPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAEL
EDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEE
KISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIRSEVSQVKREKENIQ
TLLKSKEQEVNELLQKFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQ
NQLAECKKQHQEVISVYRMHLLYAVQGQMDEDVQKVLKQILTMCKNQSQKK

--------------------------------------------------------------
>2045_2045_17_ADAMTS12-RAI14_ADAMTS12_chr5_33881224_ENST00000515401_RAI14_chr5_34757573_ENST00000512629_length(transcript)=3472nt_BP=652nt
GCTTAAAAAAGCACAGGGAGATCGCGGGCAGCTTTGCAGTCGCTGCCTTCTCGCGCCTGACCATGCACCCCTGCATCTTCCTGCTGGGCC
ACAGGCGAGCGCTTTATTTCTGGAGCTGAGGGCTAAAACTTTTTTGACTTTTCTTCTCCTCAACATCTGAATCATGCCATGTGCCCAGAG
GAGCTGGCTTGCAAACCTTTCCGTGGTGGCTCAGCTCCTTAACTTTGGGGCGCTTTGCTATGGGAGACAGCCTCAGCCAGGCCCGGTTCG
CTTCCCGGACAGGAGGCAAGAGCATTTTATCAAGGGCCTGCCAGAATACCACGTGGTGGGTCCAGTCCGAGTAGATGCCAGTGGGCATTT
TTTGTCATATGGCTTGCACTATCCCATCACGAGCAGCAGGAGGAAGAGAGATTTGGATGGCTCAGAGGACTGGGTGTACTACAGAATTTC
TCACGAGGAGAAGGACCTGTTTTTTAACTTGACGGTCAATCAAGGATTTCTTTCCAATAGCTACATCATGGAGAAGAGATATGGGAACCT
CTCCCATGTTAAGATGATGGCTTCCTCTGCCCCCCTCTGCCATCTCAGTGGCACGGTTCTACAGCAGGGCACCAGAGTTGGGACGGCAGC
CCTCAGTGCCTGCCATGGACTGACCAATGAGTGGAACAAGAATGATGACCGGCTACTGCAGGCCGTGGAGAATGGAGATGCGGAGAAGGT
GGCCTCACTGCTCGGCAAGAAGGGGGCCAGTGCCACCAAACACGACAGTGAGGGCAAGACCGCTTTCCATCTTGCTGCTGCAAAAGGACA
CGTGGAATGCCTCAGGGTCATGATTACACATGGTGTGGATGTGACAGCCCAAGATACTACCGGACACAGCGCCTTACATCTCGCAGCCAA
GAACAGCCACCATGAATGCATCAGGAAGCTGCTTCAGTCTAAATGCCCAGCCGAAAGTGTCGACAGCTCTGGGAAAACAGCTTTACATTA
TGCAGCGGCTCAGGGCTGCCTTCAAGCTGTGCAGATTCTCTGCGAACACAAGAGCCCCATAAACCTCAAAGATTTGGATGGGAATATACC
GCTGCTTCTTGCTGTACAAAATGGTCACAGTGAGATCTGTCACTTTCTCCTGGATCATGGAGCAGATGTCAATTCCAGGAACAAAAGTGG
AAGAACTGCTCTCATGCTGGCCTGTGAGATTGGCAGCTCTAACGCTGTGGAAGCCTTAATTAAAAAGGGTGCAGACCTAAACCTTGTAGA
TTCTCTTGGATACAATGCCTTACATTATTCCAAACTCTCAGAAAATGCAGGAATTCAAAGCCTTCTATTATCAAAAATCTCTCAGGATGC
TGATTTAAAGACCCCAACAAAACCAAAGCAGTTGAGTGATGTCTCTTCCCCAAGATCAATAACTTCGACTCCACTATCGGGAAAGGAATC
GGTATTTTTTGCTGAACCACCCTTCAAGGCTGAGATCAGTTCTATACGAGAAAACAAAGACAGACTAAGTGACAGTACTACAGGTGCTGA
TAGCTTATTGGATATAAGTTCTGAAGCTGACCAACAAGATCTTCTCTCTCTATTGCAAGCAAAAGTTGCTTCCCTTACCTTACACAATAA
GGAGTTACAAGATAAATTACAGGCCAAATCACCCAAGGAGGCGGAAGCAGACCTAAGCTTTGACTCATACCATTCCACCCAAACTGACTT
GGGCCCATCCCTGGGAAAACCTGGTGAAACCTCTCCCCCAGACTCCAAATCATCTCCATCTGTCTTAATACATTCTTTAGGTAAATCCAC
TACTGACAATGATGTCAGAATTCAGCAACTGCAAGAGATTTTGCAAGATCTACAGAAGAGATTAGAGAGCTCTGAAGCAGAGAGAAAACA
GCTACAGGTCGAACTCCAATCCCGAAGGGCAGAACTGGTATGCTTAAACAACACTGAGATTTCAGAGAACAGCTCTGACCTCAGCCAGAA
ACTTAAAGAAACTCAGAGCAAATACGAGGAGGCTATGAAAGAAGTCCTTAGTGTGCAGAAGCAGATGAAACTCGGTCTTGTCTCACCTGA
AAGCATGGATAATTATTCACATTTCCACGAGCTGAGGGTCACGGAAGAGGAAATAAATGTGCTAAAGCAGGATCTGCAGAATGCATTAGA
AGAAAGTGAAAGAAATAAAGAGAAAGTGAGAGAGTTAGAGGAAAAACTGGTAGAGAGGGAGAAAGGTACAGTGATTAAGCCACCTGTGGA
AGAGTACGAGGAAATGAAAAGTTCATATTGCTCTGTTATTGAGAATATGAATAAGGAGAAAGCATTTTTGTTTGAGAAATACCAAGAAGC
CCAAGAAGAAATCATGAAATTAAAAGACACACTAAAAAGTCAGATGACACAGGAAGCCAGTGATGAAGCTGAGGACATGAAAGAAGCCAT
GAATAGGATGATAGATGAACTCAATAAACAGGTGAGCGAGCTGTCACAGCTGTACAAAGAAGCCCAGGCTGAGCTGGAGGATTACAGGAA
GAGGAAATCTCTAGAGGATGTCACAGCTGAATATATCCATAAAGCAGAGCATGAGAAACTGATGCAATTGACAAACGTGTCCAGGGCTAA
AGCAGAAGATGCACTGTCTGAAATGAAGTCTCAGTATTCAAAAGTGTTGAATGAGTTGACCCAGCTCAAACAACTGGTGGATGCACAAAA
AGAGAACTCTGTCTCTATCACAGAACATTTGCAAGTGATAACCACGCTGCGGACTGCAGCAAAAGAGATGGAAGAAAAAATAAGCAATCT
TAAGGAACACCTTGCAAGCAAGGAAGTGGAAGTAGCAAAGCTGGAGAAACAACTCTTAGAAGAGAAAGCTGCTATGACTGATGCAATGGT
ACCTCGGTCTTCCTATGAAAAACTCCAGTCATCCTTAGAGAGTGAAGTGAGTGTGTTGGCATCGAAATTAAAGGAATCTGTGAAAGAGAA
AGAGAAGGTCCATTCAGAGGTTGTCCAGATTAGAAGTGAGGTCTCACAGGTGAAAAGAGAAAAGGAAAATATTCAGACTCTCTTGAAATC
CAAAGAGCAAGAAGTAAATGAACTTCTGCAAAAATTCCAGCAAGCTCAGGAAGAACTTGCAGAAATGAAAAGATACGCTGAGAGCTCTTC
AAAACTGGAGGAAGATAAAGATAAAAAGATAAATGAGATGTCGAAGGAAGTCACCAAATTGAAGGAGGCCTTGAACAGCCTCTCCCAGCT
CTCCTACTCAACAAGCTCATCCAAAAGGCAGAGTCAGCAGCTGGAGGCGCTGCAGCAGCAAGTCAAACAGCTCCAGAACCAGCTGGCGGA
ATGCAAGAAACAACACCAGGAGGTCATATCAGTTTACAGAATGCATCTTCTGTATGCTGTGCAGGGCCAGATGGATGAAGATGTCCAGAA
AGTACTGAAGCAAATCCTTACCATGTGTAAAAACCAGTCTCAAAAGAAGTAA

>2045_2045_17_ADAMTS12-RAI14_ADAMTS12_chr5_33881224_ENST00000515401_RAI14_chr5_34757573_ENST00000512629_length(amino acids)=1103AA_BP=163
MPCAQRSWLANLSVVAQLLNFGALCYGRQPQPGPVRFPDRRQEHFIKGLPEYHVVGPVRVDASGHFLSYGLHYPITSSRRKRDLDGSEDW
VYYRISHEEKDLFFNLTVNQGFLSNSYIMEKRYGNLSHVKMMASSAPLCHLSGTVLQQGTRVGTAALSACHGLTNEWNKNDDRLLQAVEN
GDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSG
KTALHYAAAQGCLQAVQILCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEALIKKGA
DLNLVDSLGYNALHYSKLSENAGIQSLLLSKISQDADLKTPTKPKQLSDVSSPRSITSTPLSGKESVFFAEPPFKAEISSIRENKDRLSD
STTGADSLLDISSEADQQDLLSLLQAKVASLTLHNKELQDKLQAKSPKEAEADLSFDSYHSTQTDLGPSLGKPGETSPPDSKSSPSVLIH
SLGKSTTDNDVRIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNNTEISENSSDLSQKLKETQSKYEEAMKEVLSVQKQMKL
GLVSPESMDNYSHFHELRVTEEEINVLKQDLQNALEESERNKEKVRELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLF
EKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSLEDVTAEYIHKAEHEKLMQLT
NVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAA
MTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIRSEVSQVKREKENIQTLLKSKEQEVNELLQKFQQAQEELAEMKR
YAESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQNQLAECKKQHQEVISVYRMHLLYAVQGQM
DEDVQKVLKQILTMCKNQSQKKX

--------------------------------------------------------------
>2045_2045_18_ADAMTS12-RAI14_ADAMTS12_chr5_33881224_ENST00000515401_RAI14_chr5_34757573_ENST00000515799_length(transcript)=3601nt_BP=652nt
GCTTAAAAAAGCACAGGGAGATCGCGGGCAGCTTTGCAGTCGCTGCCTTCTCGCGCCTGACCATGCACCCCTGCATCTTCCTGCTGGGCC
ACAGGCGAGCGCTTTATTTCTGGAGCTGAGGGCTAAAACTTTTTTGACTTTTCTTCTCCTCAACATCTGAATCATGCCATGTGCCCAGAG
GAGCTGGCTTGCAAACCTTTCCGTGGTGGCTCAGCTCCTTAACTTTGGGGCGCTTTGCTATGGGAGACAGCCTCAGCCAGGCCCGGTTCG
CTTCCCGGACAGGAGGCAAGAGCATTTTATCAAGGGCCTGCCAGAATACCACGTGGTGGGTCCAGTCCGAGTAGATGCCAGTGGGCATTT
TTTGTCATATGGCTTGCACTATCCCATCACGAGCAGCAGGAGGAAGAGAGATTTGGATGGCTCAGAGGACTGGGTGTACTACAGAATTTC
TCACGAGGAGAAGGACCTGTTTTTTAACTTGACGGTCAATCAAGGATTTCTTTCCAATAGCTACATCATGGAGAAGAGATATGGGAACCT
CTCCCATGTTAAGATGATGGCTTCCTCTGCCCCCCTCTGCCATCTCAGTGGCACGGTTCTACAGCAGGGCACCAGAGTTGGGACGGCAGC
CCTCAGTGCCTGCCATGGACTGACCAATGAGTGGAACAAGAATGATGACCGGCTACTGCAGGCCGTGGAGAATGGAGATGCGGAGAAGGT
GGCCTCACTGCTCGGCAAGAAGGGGGCCAGTGCCACCAAACACGACAGTGAGGGCAAGACCGCTTTCCATCTTGCTGCTGCAAAAGGACA
CGTGGAATGCCTCAGGGTCATGATTACACATGGTGTGGATGTGACAGCCCAAGATACTACCGGACACAGCGCCTTACATCTCGCAGCCAA
GAACAGCCACCATGAATGCATCAGGAAGCTGCTTCAGTCTAAATGCCCAGCCGAAAGTGTCGACAGCTCTGGGAAAACAGCTTTACATTA
TGCAGCGGCTCAGGGCTGCCTTCAAGCTGTGCAGATTCTCTGCGAACACAAGAGCCCCATAAACCTCAAAGATTTGGATGGGAATATACC
GCTGCTTCTTGCTGTACAAAATGGTCACAGTGAGATCTGTCACTTTCTCCTGGATCATGGAGCAGATGTCAATTCCAGGAACAAAAGTGG
AAGAACTGCTCTCATGCTGGCCTGTGAGATTGGCAGCTCTAACGCTGTGGAAGCCTTAATTAAAAAGGGTGCAGACCTAAACCTTGTAGA
TTCTCTTGGATACAATGCCTTACATTATTCCAAACTCTCAGAAAATGCAGGAATTCAAAGCCTTCTATTATCAAAAATCTCTCAGGATGC
TGATTTAAAGACCCCAACAAAACCAAAGCAGCATGACCAAGTCTCTAAAATAAGCTCAGAAAGAAGTGGAACTCCAAAAAAACGCAAAGC
TCCACCACCTCCTATCAGTCCTACCCAGTTGAGTGATGTCTCTTCCCCAAGATCAATAACTTCGACTCCACTATCGGGAAAGGAATCGGT
ATTTTTTGCTGAACCACCCTTCAAGGCTGAGATCAGTTCTATACGAGAAAACAAAGACAGACTAAGTGACAGTACTACAGGTGCTGATAG
CTTATTGGATATAAGTTCTGAAGCTGACCAACAAGATCTTCTCTCTCTATTGCAAGCAAAAGTTGCTTCCCTTACCTTACACAATAAGGA
GTTACAAGATAAATTACAGGCCAAATCACCCAAGGAGGCGGAAGCAGACCTAAGCTTTGACTCATACCATTCCACCCAAACTGACTTGGG
CCCATCCCTGGGAAAACCTGGTGAAACCTCTCCCCCAGACTCCAAATCATCTCCATCTGTCTTAATACATTCTTTAGGTAAATCCACTAC
TGACAATGATGTCAGAATTCAGCAACTGCAAGAGATTTTGCAAGATCTACAGAAGAGATTAGAGAGCTCTGAAGCAGAGAGAAAACAGCT
ACAGGTCGAACTCCAATCCCGAAGGGCAGAACTGGTATGCTTAAACAACACTGAGATTTCAGAGAACAGCTCTGACCTCAGCCAGAAACT
TAAAGAAACTCAGAGCAAATACGAGGAGGCTATGAAAGAAGTCCTTAGTGTGCAGAAGCAGATGAAACTCGGTCTTGTCTCACCTGAAAG
CATGGATAATTATTCACATTTCCACGAGCTGAGGGTCACGGAAGAGGAAATAAATGTGCTAAAGCAGGATCTGCAGAATGCATTAGAAGA
AAGTGAAAGAAATAAAGAGAAAGTGAGAGAGTTAGAGGAAAAACTGGTAGAGAGGGAGAAAGGTACAGTGATTAAGCCACCTGTGGAAGA
GTACGAGGAAATGAAAAGTTCATATTGCTCTGTTATTGAGAATATGAATAAGGAGAAAGCATTTTTGTTTGAGAAATACCAAGAAGCCCA
AGAAGAAATCATGAAATTAAAAGACACACTAAAAAGTCAGATGACACAGGAAGCCAGTGATGAAGCTGAGGACATGAAAGAAGCCATGAA
TAGGATGATAGATGAACTCAATAAACAGGTGAGCGAGCTGTCACAGCTGTACAAAGAAGCCCAGGCTGAGCTGGAGGATTACAGGAAGAG
GAAATCTCTAGAGGATGTCACAGCTGAATATATCCATAAAGCAGAGCATGAGAAACTGATGCAATTGACAAACGTGTCCAGGGCTAAAGC
AGAAGATGCACTGTCTGAAATGAAGTCTCAGTATTCAAAAGTGTTGAATGAGTTGACCCAGCTCAAACAACTGGTGGATGCACAAAAAGA
GAACTCTGTCTCTATCACAGAACATTTGCAAGTGATAACCACGCTGCGGACTGCAGCAAAAGAGATGGAAGAAAAAATAAGCAATCTTAA
GGAACACCTTGCAAGCAAGGAAGTGGAAGTAGCAAAGCTGGAGAAACAACTCTTAGAAGAGAAAGCTGCTATGACTGATGCAATGGTACC
TCGGTCTTCCTATGAAAAACTCCAGTCATCCTTAGAGAGTGAAGTGAGTGTGTTGGCATCGAAATTAAAGGAATCTGTGAAAGAGAAAGA
GAAGGTCCATTCAGAGGTTGTCCAGATTAGAAGTGAGGTCTCACAGGTGAAAAGAGAAAAGGAAAATATTCAGACTCTCTTGAAATCCAA
AGAGCAAGAAGTAAATGAACTTCTGCAAAAATTCCAGCAAGCTCAGGAAGAACTTGCAGAAATGAAAAGATACGCTGAGAGCTCTTCAAA
ACTGGAGGAAGATAAAGATAAAAAGATAAATGAGATGTCGAAGGAAGTCACCAAATTGAAGGAGGCCTTGAACAGCCTCTCCCAGCTCTC
CTACTCAACAAGCTCATCCAAAAGGCAGAGTCAGCAGCTGGAGGCGCTGCAGCAGCAAGTCAAACAGCTCCAGAACCAGCTGGCGGAATG
CAAGAAACAACACCAGGAGGTCATATCAGTTTACAGAATGCATCTTCTGTATGCTGTGCAGGGCCAGATGGATGAAGATGTCCAGAAAGT
ACTGAAGCAAATCCTTACCATGTGTAAAAACCAGTCTCAAAAGAAGTAAAGTGGATTCCTTGGCAGGACACTGCCCCTTGTCATCTGTCT
T

>2045_2045_18_ADAMTS12-RAI14_ADAMTS12_chr5_33881224_ENST00000515401_RAI14_chr5_34757573_ENST00000515799_length(amino acids)=1131AA_BP=163
MPCAQRSWLANLSVVAQLLNFGALCYGRQPQPGPVRFPDRRQEHFIKGLPEYHVVGPVRVDASGHFLSYGLHYPITSSRRKRDLDGSEDW
VYYRISHEEKDLFFNLTVNQGFLSNSYIMEKRYGNLSHVKMMASSAPLCHLSGTVLQQGTRVGTAALSACHGLTNEWNKNDDRLLQAVEN
GDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSG
KTALHYAAAQGCLQAVQILCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEALIKKGA
DLNLVDSLGYNALHYSKLSENAGIQSLLLSKISQDADLKTPTKPKQHDQVSKISSERSGTPKKRKAPPPPISPTQLSDVSSPRSITSTPL
SGKESVFFAEPPFKAEISSIRENKDRLSDSTTGADSLLDISSEADQQDLLSLLQAKVASLTLHNKELQDKLQAKSPKEAEADLSFDSYHS
TQTDLGPSLGKPGETSPPDSKSSPSVLIHSLGKSTTDNDVRIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNNTEISENSS
DLSQKLKETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNYSHFHELRVTEEEINVLKQDLQNALEESERNKEKVRELEEKLVEREKGTVI
KPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAEL
EDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEE
KISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIRSEVSQVKREKENIQ
TLLKSKEQEVNELLQKFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQ
NQLAECKKQHQEVISVYRMHLLYAVQGQMDEDVQKVLKQILTMCKNQSQKK

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for ADAMTS12-RAI14


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for ADAMTS12-RAI14


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for ADAMTS12-RAI14


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneADAMTS12C0036341Schizophrenia1PSYGENET