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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:CANX-SQSTM1 (FusionGDB2 ID:HG821TG8878)

Fusion Gene Summary for CANX-SQSTM1

check button Fusion gene summary
Fusion gene informationFusion gene name: CANX-SQSTM1
Fusion gene ID: hg821tg8878
HgeneTgene
Gene symbol

CANX

SQSTM1

Gene ID

821

8878

Gene namecalnexinsequestosome 1
SynonymsCNX|IP90|P90A170|DMRV|FTDALS3|NADGP|OSIL|PDB3|ZIP3|p60|p62|p62B
Cytomap('CANX')('SQSTM1')

5q35.3

5q35.3

Type of geneprotein-codingprotein-coding
Descriptioncalnexinepididymis secretory sperm binding proteinmajor histocompatibility complex class I antigen-binding protein p88sequestosome-1EBI3-associated protein of 60 kDaEBI3-associated protein p60EBIAPautophagy receptor p62oxidative stress induced likephosphotyrosine independent ligand for the Lck SH2 domain p62phosphotyrosine-independent ligand for the Lck SH2 domain
Modification date2020031320200327
UniProtAcc

P27824

Q13501

Ensembl transtripts involved in fusion geneENST00000503126, ENST00000247461, 
ENST00000415618, ENST00000452673, 
ENST00000504734, ENST00000512607, 
ENST00000247461, ENST00000415618, 
ENST00000452673, ENST00000504734, 
ENST00000512607, ENST00000503126, 
Fusion gene scores* DoF score15 X 16 X 11=264033 X 21 X 17=11781
# samples 2138
** MAII scorelog2(21/2640*10)=-3.65207669657969
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(38/11781*10)=-4.95431877505661
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CANX [Title/Abstract] AND SQSTM1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCANX(179134191)-SQSTM1(179260032), # samples:1
CANX(179137066)-SQSTM1(179260032), # samples:1
Anticipated loss of major functional domain due to fusion event.CANX-SQSTM1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
CANX-SQSTM1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
CANX-SQSTM1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
CANX-SQSTM1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneSQSTM1

GO:0006914

autophagy

20452972

TgeneSQSTM1

GO:0007032

endosome organization

27368102

TgeneSQSTM1

GO:0031397

negative regulation of protein ubiquitination

20452972

TgeneSQSTM1

GO:0061635

regulation of protein complex stability

25127057

TgeneSQSTM1

GO:1905719

protein localization to perinuclear region of cytoplasm

27368102


check buttonFusion gene breakpoints across CANX (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across SQSTM1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUADTCGA-78-8640-01ACANXchr5

179134191

+SQSTM1chr5

179260032

+
ChimerDB4OVTCGA-20-0991-01ACANXchr5

179137066

+SQSTM1chr5

179260032

+


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Fusion Gene ORF analysis for CANX-SQSTM1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000503126ENST00000376929CANXchr5

179134191

+SQSTM1chr5

179260032

+
3UTR-3CDSENST00000503126ENST00000376929CANXchr5

179137066

+SQSTM1chr5

179260032

+
3UTR-intronENST00000503126ENST00000360718CANXchr5

179134191

+SQSTM1chr5

179260032

+
3UTR-intronENST00000503126ENST00000360718CANXchr5

179137066

+SQSTM1chr5

179260032

+
3UTR-intronENST00000503126ENST00000389805CANXchr5

179134191

+SQSTM1chr5

179260032

+
3UTR-intronENST00000503126ENST00000389805CANXchr5

179137066

+SQSTM1chr5

179260032

+
3UTR-intronENST00000503126ENST00000402874CANXchr5

179134191

+SQSTM1chr5

179260032

+
3UTR-intronENST00000503126ENST00000402874CANXchr5

179137066

+SQSTM1chr5

179260032

+
3UTR-intronENST00000503126ENST00000506690CANXchr5

179134191

+SQSTM1chr5

179260032

+
3UTR-intronENST00000503126ENST00000506690CANXchr5

179137066

+SQSTM1chr5

179260032

+
3UTR-intronENST00000503126ENST00000510187CANXchr5

179134191

+SQSTM1chr5

179260032

+
3UTR-intronENST00000503126ENST00000510187CANXchr5

179137066

+SQSTM1chr5

179260032

+
5CDS-intronENST00000247461ENST00000360718CANXchr5

179134191

+SQSTM1chr5

179260032

+
5CDS-intronENST00000247461ENST00000360718CANXchr5

179137066

+SQSTM1chr5

179260032

+
5CDS-intronENST00000247461ENST00000389805CANXchr5

179134191

+SQSTM1chr5

179260032

+
5CDS-intronENST00000247461ENST00000389805CANXchr5

179137066

+SQSTM1chr5

179260032

+
5CDS-intronENST00000247461ENST00000402874CANXchr5

179134191

+SQSTM1chr5

179260032

+
5CDS-intronENST00000247461ENST00000402874CANXchr5

179137066

+SQSTM1chr5

179260032

+
5CDS-intronENST00000247461ENST00000506690CANXchr5

179134191

+SQSTM1chr5

179260032

+
5CDS-intronENST00000247461ENST00000506690CANXchr5

179137066

+SQSTM1chr5

179260032

+
5CDS-intronENST00000247461ENST00000510187CANXchr5

179134191

+SQSTM1chr5

179260032

+
5CDS-intronENST00000247461ENST00000510187CANXchr5

179137066

+SQSTM1chr5

179260032

+
5CDS-intronENST00000415618ENST00000360718CANXchr5

179134191

+SQSTM1chr5

179260032

+
5CDS-intronENST00000415618ENST00000360718CANXchr5

179137066

+SQSTM1chr5

179260032

+
5CDS-intronENST00000415618ENST00000389805CANXchr5

179134191

+SQSTM1chr5

179260032

+
5CDS-intronENST00000415618ENST00000389805CANXchr5

179137066

+SQSTM1chr5

179260032

+
5CDS-intronENST00000415618ENST00000402874CANXchr5

179134191

+SQSTM1chr5

179260032

+
5CDS-intronENST00000415618ENST00000402874CANXchr5

179137066

+SQSTM1chr5

179260032

+
5CDS-intronENST00000415618ENST00000506690CANXchr5

179134191

+SQSTM1chr5

179260032

+
5CDS-intronENST00000415618ENST00000506690CANXchr5

179137066

+SQSTM1chr5

179260032

+
5CDS-intronENST00000415618ENST00000510187CANXchr5

179134191

+SQSTM1chr5

179260032

+
5CDS-intronENST00000415618ENST00000510187CANXchr5

179137066

+SQSTM1chr5

179260032

+
5CDS-intronENST00000452673ENST00000360718CANXchr5

179134191

+SQSTM1chr5

179260032

+
5CDS-intronENST00000452673ENST00000360718CANXchr5

179137066

+SQSTM1chr5

179260032

+
5CDS-intronENST00000452673ENST00000389805CANXchr5

179134191

+SQSTM1chr5

179260032

+
5CDS-intronENST00000452673ENST00000389805CANXchr5

179137066

+SQSTM1chr5

179260032

+
5CDS-intronENST00000452673ENST00000402874CANXchr5

179134191

+SQSTM1chr5

179260032

+
5CDS-intronENST00000452673ENST00000402874CANXchr5

179137066

+SQSTM1chr5

179260032

+
5CDS-intronENST00000452673ENST00000506690CANXchr5

179134191

+SQSTM1chr5

179260032

+
5CDS-intronENST00000452673ENST00000506690CANXchr5

179137066

+SQSTM1chr5

179260032

+
5CDS-intronENST00000452673ENST00000510187CANXchr5

179134191

+SQSTM1chr5

179260032

+
5CDS-intronENST00000452673ENST00000510187CANXchr5

179137066

+SQSTM1chr5

179260032

+
5CDS-intronENST00000504734ENST00000360718CANXchr5

179134191

+SQSTM1chr5

179260032

+
5CDS-intronENST00000504734ENST00000360718CANXchr5

179137066

+SQSTM1chr5

179260032

+
5CDS-intronENST00000504734ENST00000389805CANXchr5

179134191

+SQSTM1chr5

179260032

+
5CDS-intronENST00000504734ENST00000389805CANXchr5

179137066

+SQSTM1chr5

179260032

+
5CDS-intronENST00000504734ENST00000402874CANXchr5

179134191

+SQSTM1chr5

179260032

+
5CDS-intronENST00000504734ENST00000402874CANXchr5

179137066

+SQSTM1chr5

179260032

+
5CDS-intronENST00000504734ENST00000506690CANXchr5

179134191

+SQSTM1chr5

179260032

+
5CDS-intronENST00000504734ENST00000506690CANXchr5

179137066

+SQSTM1chr5

179260032

+
5CDS-intronENST00000504734ENST00000510187CANXchr5

179134191

+SQSTM1chr5

179260032

+
5CDS-intronENST00000504734ENST00000510187CANXchr5

179137066

+SQSTM1chr5

179260032

+
5CDS-intronENST00000512607ENST00000360718CANXchr5

179137066

+SQSTM1chr5

179260032

+
5CDS-intronENST00000512607ENST00000389805CANXchr5

179137066

+SQSTM1chr5

179260032

+
5CDS-intronENST00000512607ENST00000402874CANXchr5

179137066

+SQSTM1chr5

179260032

+
5CDS-intronENST00000512607ENST00000506690CANXchr5

179137066

+SQSTM1chr5

179260032

+
5CDS-intronENST00000512607ENST00000510187CANXchr5

179137066

+SQSTM1chr5

179260032

+
In-frameENST00000247461ENST00000376929CANXchr5

179134191

+SQSTM1chr5

179260032

+
In-frameENST00000247461ENST00000376929CANXchr5

179137066

+SQSTM1chr5

179260032

+
In-frameENST00000415618ENST00000376929CANXchr5

179134191

+SQSTM1chr5

179260032

+
In-frameENST00000415618ENST00000376929CANXchr5

179137066

+SQSTM1chr5

179260032

+
In-frameENST00000452673ENST00000376929CANXchr5

179134191

+SQSTM1chr5

179260032

+
In-frameENST00000452673ENST00000376929CANXchr5

179137066

+SQSTM1chr5

179260032

+
In-frameENST00000504734ENST00000376929CANXchr5

179134191

+SQSTM1chr5

179260032

+
In-frameENST00000504734ENST00000376929CANXchr5

179137066

+SQSTM1chr5

179260032

+
In-frameENST00000512607ENST00000376929CANXchr5

179137066

+SQSTM1chr5

179260032

+
intron-3CDSENST00000512607ENST00000376929CANXchr5

179134191

+SQSTM1chr5

179260032

+
intron-intronENST00000512607ENST00000360718CANXchr5

179134191

+SQSTM1chr5

179260032

+
intron-intronENST00000512607ENST00000389805CANXchr5

179134191

+SQSTM1chr5

179260032

+
intron-intronENST00000512607ENST00000402874CANXchr5

179134191

+SQSTM1chr5

179260032

+
intron-intronENST00000512607ENST00000506690CANXchr5

179134191

+SQSTM1chr5

179260032

+
intron-intronENST00000512607ENST00000510187CANXchr5

179134191

+SQSTM1chr5

179260032

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000504734CANXchr5179134191+ENST00000376929SQSTM1chr5179260032+2545494371062341
ENST00000415618CANXchr5179134191+ENST00000376929SQSTM1chr5179260032+2535484271052341
ENST00000452673CANXchr5179134191+ENST00000376929SQSTM1chr5179260032+25024511471019290
ENST00000247461CANXchr5179134191+ENST00000376929SQSTM1chr5179260032+25555042001072290
ENST00000504734CANXchr5179137066+ENST00000376929SQSTM1chr5179260032+2962911371479480
ENST00000415618CANXchr5179137066+ENST00000376929SQSTM1chr5179260032+2952901271469480
ENST00000452673CANXchr5179137066+ENST00000376929SQSTM1chr5179260032+29198681471436429
ENST00000247461CANXchr5179137066+ENST00000376929SQSTM1chr5179260032+29729212001489429
ENST00000512607CANXchr5179137066+ENST00000376929SQSTM1chr5179260032+28317802661348360

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000504734ENST00000376929CANXchr5179134191+SQSTM1chr5179260032+0.000908030.999092
ENST00000415618ENST00000376929CANXchr5179134191+SQSTM1chr5179260032+0.0008962720.9991037
ENST00000452673ENST00000376929CANXchr5179134191+SQSTM1chr5179260032+0.001601580.99839836
ENST00000247461ENST00000376929CANXchr5179134191+SQSTM1chr5179260032+0.0016408050.99835914
ENST00000504734ENST00000376929CANXchr5179137066+SQSTM1chr5179260032+0.0007102640.99928975
ENST00000415618ENST00000376929CANXchr5179137066+SQSTM1chr5179260032+0.000700410.9992995
ENST00000452673ENST00000376929CANXchr5179137066+SQSTM1chr5179260032+0.0013593120.9986407
ENST00000247461ENST00000376929CANXchr5179137066+SQSTM1chr5179260032+0.0014033780.9985966
ENST00000512607ENST00000376929CANXchr5179137066+SQSTM1chr5179260032+0.0009418170.9990582

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Fusion Genomic Features for CANX-SQSTM1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
CANXchr5179137066+SQSTM1chr5179260031+4.28E-050.9999572
CANXchr5179134191+SQSTM1chr5179260031+3.08E-060.9999969
CANXchr5179137066+SQSTM1chr5179260031+4.28E-050.9999572
CANXchr5179134191+SQSTM1chr5179260031+3.08E-060.9999969

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for CANX-SQSTM1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr5:179134191/chr5:179260032)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
CANX

P27824

SQSTM1

Q13501

FUNCTION: Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor-mediated endocytosis at the synapse.FUNCTION: Autophagy receptor required for selective macroautophagy (aggrephagy). Functions as a bridge between polyubiquitinated cargo and autophagosomes. Interacts directly with both the cargo to become degraded and an autophagy modifier of the MAP1 LC3 family (PubMed:16286508, PubMed:20168092, PubMed:24128730, PubMed:28404643, PubMed:22622177). Along with WDFY3, involved in the formation and autophagic degradation of cytoplasmic ubiquitin-containing inclusions (p62 bodies, ALIS/aggresome-like induced structures). Along with WDFY3, required to recruit ubiquitinated proteins to PML bodies in the nucleus (PubMed:24128730, PubMed:20168092). May regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin-1. May play a role in titin/TTN downstream signaling in muscle cells. May regulate signaling cascades through ubiquitination. Adapter that mediates the interaction between TRAF6 and CYLD (By similarity). May be involved in cell differentiation, apoptosis, immune response and regulation of K(+) channels. Involved in endosome organization by retaining vesicles in the perinuclear cloud: following ubiquitination by RNF26, attracts specific vesicle-associated adapters, forming a molecular bridge that restrains cognate vesicles in the perinuclear region and organizes the endosomal pathway for efficient cargo transport (PubMed:27368102). Promotes relocalization of 'Lys-63'-linked ubiquitinated STING1 to autophagosomes (PubMed:29496741). Acts as an activator of the NFE2L2/NRF2 pathway via interaction with KEAP1: interaction inactivates the BCR(KEAP1) complex, promoting nuclear accumulation of NFE2L2/NRF2 and subsequent expression of cytoprotective genes (PubMed:20452972, PubMed:28380357, PubMed:33393215). {ECO:0000250|UniProtKB:O08623, ECO:0000250|UniProtKB:Q64337, ECO:0000269|PubMed:10356400, ECO:0000269|PubMed:10747026, ECO:0000269|PubMed:11244088, ECO:0000269|PubMed:12471037, ECO:0000269|PubMed:15340068, ECO:0000269|PubMed:15802564, ECO:0000269|PubMed:15911346, ECO:0000269|PubMed:15953362, ECO:0000269|PubMed:16079148, ECO:0000269|PubMed:16286508, ECO:0000269|PubMed:19931284, ECO:0000269|PubMed:20168092, ECO:0000269|PubMed:20452972, ECO:0000269|PubMed:22622177, ECO:0000269|PubMed:24128730, ECO:0000269|PubMed:27368102, ECO:0000269|PubMed:28380357, ECO:0000269|PubMed:28404643, ECO:0000269|PubMed:29496741, ECO:0000269|PubMed:33393215}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneSQSTM1chr5:179134191chr5:179260032ENST0000036071837272_294167357.0Compositional biasNote=Ser-rich
TgeneSQSTM1chr5:179134191chr5:179260032ENST0000037692959272_294167357.0Compositional biasNote=Ser-rich
TgeneSQSTM1chr5:179134191chr5:179260032ENST0000038980548272_294251441.0Compositional biasNote=Ser-rich
TgeneSQSTM1chr5:179134191chr5:179260032ENST0000040287448272_294167357.0Compositional biasNote=Ser-rich
TgeneSQSTM1chr5:179137066chr5:179260032ENST0000036071837272_294167357.0Compositional biasNote=Ser-rich
TgeneSQSTM1chr5:179137066chr5:179260032ENST0000037692959272_294167357.0Compositional biasNote=Ser-rich
TgeneSQSTM1chr5:179137066chr5:179260032ENST0000038980548272_294251441.0Compositional biasNote=Ser-rich
TgeneSQSTM1chr5:179137066chr5:179260032ENST0000040287448272_294167357.0Compositional biasNote=Ser-rich
TgeneSQSTM1chr5:179134191chr5:179260032ENST0000036071837389_434167357.0DomainUBA
TgeneSQSTM1chr5:179134191chr5:179260032ENST0000037692959389_434167357.0DomainUBA
TgeneSQSTM1chr5:179134191chr5:179260032ENST0000038980548389_434251441.0DomainUBA
TgeneSQSTM1chr5:179134191chr5:179260032ENST0000040287448389_434167357.0DomainUBA
TgeneSQSTM1chr5:179137066chr5:179260032ENST0000036071837389_434167357.0DomainUBA
TgeneSQSTM1chr5:179137066chr5:179260032ENST0000037692959389_434167357.0DomainUBA
TgeneSQSTM1chr5:179137066chr5:179260032ENST0000038980548389_434251441.0DomainUBA
TgeneSQSTM1chr5:179137066chr5:179260032ENST0000040287448389_434167357.0DomainUBA
TgeneSQSTM1chr5:179134191chr5:179260032ENST0000036071837228_233167357.0MotifNote=TRAF6-binding
TgeneSQSTM1chr5:179134191chr5:179260032ENST0000036071837336_341167357.0MotifNote=LIR
TgeneSQSTM1chr5:179134191chr5:179260032ENST0000037692959228_233167357.0MotifNote=TRAF6-binding
TgeneSQSTM1chr5:179134191chr5:179260032ENST0000037692959336_341167357.0MotifNote=LIR
TgeneSQSTM1chr5:179134191chr5:179260032ENST0000038980548336_341251441.0MotifNote=LIR
TgeneSQSTM1chr5:179134191chr5:179260032ENST0000040287448228_233167357.0MotifNote=TRAF6-binding
TgeneSQSTM1chr5:179134191chr5:179260032ENST0000040287448336_341167357.0MotifNote=LIR
TgeneSQSTM1chr5:179137066chr5:179260032ENST0000036071837228_233167357.0MotifNote=TRAF6-binding
TgeneSQSTM1chr5:179137066chr5:179260032ENST0000036071837336_341167357.0MotifNote=LIR
TgeneSQSTM1chr5:179137066chr5:179260032ENST0000037692959228_233167357.0MotifNote=TRAF6-binding
TgeneSQSTM1chr5:179137066chr5:179260032ENST0000037692959336_341167357.0MotifNote=LIR
TgeneSQSTM1chr5:179137066chr5:179260032ENST0000038980548336_341251441.0MotifNote=LIR
TgeneSQSTM1chr5:179137066chr5:179260032ENST0000040287448228_233167357.0MotifNote=TRAF6-binding
TgeneSQSTM1chr5:179137066chr5:179260032ENST0000040287448336_341167357.0MotifNote=LIR
TgeneSQSTM1chr5:179134191chr5:179260032ENST0000036071837170_220167357.0RegionNote=LIM protein-binding (LB)
TgeneSQSTM1chr5:179134191chr5:179260032ENST0000036071837321_342167357.0RegionMAP1LC3B-binding
TgeneSQSTM1chr5:179134191chr5:179260032ENST0000037692959170_220167357.0RegionNote=LIM protein-binding (LB)
TgeneSQSTM1chr5:179134191chr5:179260032ENST0000037692959321_342167357.0RegionMAP1LC3B-binding
TgeneSQSTM1chr5:179134191chr5:179260032ENST0000038980548321_342251441.0RegionMAP1LC3B-binding
TgeneSQSTM1chr5:179134191chr5:179260032ENST0000040287448170_220167357.0RegionNote=LIM protein-binding (LB)
TgeneSQSTM1chr5:179134191chr5:179260032ENST0000040287448321_342167357.0RegionMAP1LC3B-binding
TgeneSQSTM1chr5:179137066chr5:179260032ENST0000036071837170_220167357.0RegionNote=LIM protein-binding (LB)
TgeneSQSTM1chr5:179137066chr5:179260032ENST0000036071837321_342167357.0RegionMAP1LC3B-binding
TgeneSQSTM1chr5:179137066chr5:179260032ENST0000037692959170_220167357.0RegionNote=LIM protein-binding (LB)
TgeneSQSTM1chr5:179137066chr5:179260032ENST0000037692959321_342167357.0RegionMAP1LC3B-binding
TgeneSQSTM1chr5:179137066chr5:179260032ENST0000038980548321_342251441.0RegionMAP1LC3B-binding
TgeneSQSTM1chr5:179137066chr5:179260032ENST0000040287448170_220167357.0RegionNote=LIM protein-binding (LB)
TgeneSQSTM1chr5:179137066chr5:179260032ENST0000040287448321_342167357.0RegionMAP1LC3B-binding

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCANXchr5:179134191chr5:179260032ENST00000247461+415276_409101593.0RegionP domain (Extended arm)
HgeneCANXchr5:179134191chr5:179260032ENST00000247461+415278_345101593.0RegionNote=4 X approximate repeats
HgeneCANXchr5:179134191chr5:179260032ENST00000247461+415348_405101593.0RegionNote=4 X approximate repeats
HgeneCANXchr5:179134191chr5:179260032ENST00000452673+415276_409101593.0RegionP domain (Extended arm)
HgeneCANXchr5:179134191chr5:179260032ENST00000452673+415278_345101593.0RegionNote=4 X approximate repeats
HgeneCANXchr5:179134191chr5:179260032ENST00000452673+415348_405101593.0RegionNote=4 X approximate repeats
HgeneCANXchr5:179134191chr5:179260032ENST00000504734+415276_409101593.0RegionP domain (Extended arm)
HgeneCANXchr5:179134191chr5:179260032ENST00000504734+415278_345101593.0RegionNote=4 X approximate repeats
HgeneCANXchr5:179134191chr5:179260032ENST00000504734+415348_405101593.0RegionNote=4 X approximate repeats
HgeneCANXchr5:179137066chr5:179260032ENST00000247461+715276_409240593.0RegionP domain (Extended arm)
HgeneCANXchr5:179137066chr5:179260032ENST00000247461+715278_345240593.0RegionNote=4 X approximate repeats
HgeneCANXchr5:179137066chr5:179260032ENST00000247461+715348_405240593.0RegionNote=4 X approximate repeats
HgeneCANXchr5:179137066chr5:179260032ENST00000452673+715276_409240593.0RegionP domain (Extended arm)
HgeneCANXchr5:179137066chr5:179260032ENST00000452673+715278_345240593.0RegionNote=4 X approximate repeats
HgeneCANXchr5:179137066chr5:179260032ENST00000452673+715348_405240593.0RegionNote=4 X approximate repeats
HgeneCANXchr5:179137066chr5:179260032ENST00000504734+715276_409240593.0RegionP domain (Extended arm)
HgeneCANXchr5:179137066chr5:179260032ENST00000504734+715278_345240593.0RegionNote=4 X approximate repeats
HgeneCANXchr5:179137066chr5:179260032ENST00000504734+715348_405240593.0RegionNote=4 X approximate repeats
HgeneCANXchr5:179134191chr5:179260032ENST00000247461+415278_290101593.0RepeatNote=1-1
HgeneCANXchr5:179134191chr5:179260032ENST00000247461+415295_307101593.0RepeatNote=1-2
HgeneCANXchr5:179134191chr5:179260032ENST00000247461+415314_326101593.0RepeatNote=1-3
HgeneCANXchr5:179134191chr5:179260032ENST00000247461+415333_345101593.0RepeatNote=1-4
HgeneCANXchr5:179134191chr5:179260032ENST00000247461+415348_358101593.0RepeatNote=2-1
HgeneCANXchr5:179134191chr5:179260032ENST00000247461+415367_377101593.0RepeatNote=2-2
HgeneCANXchr5:179134191chr5:179260032ENST00000247461+415381_391101593.0RepeatNote=2-3
HgeneCANXchr5:179134191chr5:179260032ENST00000247461+415395_405101593.0RepeatNote=2-4
HgeneCANXchr5:179134191chr5:179260032ENST00000452673+415278_290101593.0RepeatNote=1-1
HgeneCANXchr5:179134191chr5:179260032ENST00000452673+415295_307101593.0RepeatNote=1-2
HgeneCANXchr5:179134191chr5:179260032ENST00000452673+415314_326101593.0RepeatNote=1-3
HgeneCANXchr5:179134191chr5:179260032ENST00000452673+415333_345101593.0RepeatNote=1-4
HgeneCANXchr5:179134191chr5:179260032ENST00000452673+415348_358101593.0RepeatNote=2-1
HgeneCANXchr5:179134191chr5:179260032ENST00000452673+415367_377101593.0RepeatNote=2-2
HgeneCANXchr5:179134191chr5:179260032ENST00000452673+415381_391101593.0RepeatNote=2-3
HgeneCANXchr5:179134191chr5:179260032ENST00000452673+415395_405101593.0RepeatNote=2-4
HgeneCANXchr5:179134191chr5:179260032ENST00000504734+415278_290101593.0RepeatNote=1-1
HgeneCANXchr5:179134191chr5:179260032ENST00000504734+415295_307101593.0RepeatNote=1-2
HgeneCANXchr5:179134191chr5:179260032ENST00000504734+415314_326101593.0RepeatNote=1-3
HgeneCANXchr5:179134191chr5:179260032ENST00000504734+415333_345101593.0RepeatNote=1-4
HgeneCANXchr5:179134191chr5:179260032ENST00000504734+415348_358101593.0RepeatNote=2-1
HgeneCANXchr5:179134191chr5:179260032ENST00000504734+415367_377101593.0RepeatNote=2-2
HgeneCANXchr5:179134191chr5:179260032ENST00000504734+415381_391101593.0RepeatNote=2-3
HgeneCANXchr5:179134191chr5:179260032ENST00000504734+415395_405101593.0RepeatNote=2-4
HgeneCANXchr5:179137066chr5:179260032ENST00000247461+715278_290240593.0RepeatNote=1-1
HgeneCANXchr5:179137066chr5:179260032ENST00000247461+715295_307240593.0RepeatNote=1-2
HgeneCANXchr5:179137066chr5:179260032ENST00000247461+715314_326240593.0RepeatNote=1-3
HgeneCANXchr5:179137066chr5:179260032ENST00000247461+715333_345240593.0RepeatNote=1-4
HgeneCANXchr5:179137066chr5:179260032ENST00000247461+715348_358240593.0RepeatNote=2-1
HgeneCANXchr5:179137066chr5:179260032ENST00000247461+715367_377240593.0RepeatNote=2-2
HgeneCANXchr5:179137066chr5:179260032ENST00000247461+715381_391240593.0RepeatNote=2-3
HgeneCANXchr5:179137066chr5:179260032ENST00000247461+715395_405240593.0RepeatNote=2-4
HgeneCANXchr5:179137066chr5:179260032ENST00000452673+715278_290240593.0RepeatNote=1-1
HgeneCANXchr5:179137066chr5:179260032ENST00000452673+715295_307240593.0RepeatNote=1-2
HgeneCANXchr5:179137066chr5:179260032ENST00000452673+715314_326240593.0RepeatNote=1-3
HgeneCANXchr5:179137066chr5:179260032ENST00000452673+715333_345240593.0RepeatNote=1-4
HgeneCANXchr5:179137066chr5:179260032ENST00000452673+715348_358240593.0RepeatNote=2-1
HgeneCANXchr5:179137066chr5:179260032ENST00000452673+715367_377240593.0RepeatNote=2-2
HgeneCANXchr5:179137066chr5:179260032ENST00000452673+715381_391240593.0RepeatNote=2-3
HgeneCANXchr5:179137066chr5:179260032ENST00000452673+715395_405240593.0RepeatNote=2-4
HgeneCANXchr5:179137066chr5:179260032ENST00000504734+715278_290240593.0RepeatNote=1-1
HgeneCANXchr5:179137066chr5:179260032ENST00000504734+715295_307240593.0RepeatNote=1-2
HgeneCANXchr5:179137066chr5:179260032ENST00000504734+715314_326240593.0RepeatNote=1-3
HgeneCANXchr5:179137066chr5:179260032ENST00000504734+715333_345240593.0RepeatNote=1-4
HgeneCANXchr5:179137066chr5:179260032ENST00000504734+715348_358240593.0RepeatNote=2-1
HgeneCANXchr5:179137066chr5:179260032ENST00000504734+715367_377240593.0RepeatNote=2-2
HgeneCANXchr5:179137066chr5:179260032ENST00000504734+715381_391240593.0RepeatNote=2-3
HgeneCANXchr5:179137066chr5:179260032ENST00000504734+715395_405240593.0RepeatNote=2-4
HgeneCANXchr5:179134191chr5:179260032ENST00000247461+41521_481101593.0Topological domainLumenal
HgeneCANXchr5:179134191chr5:179260032ENST00000452673+41521_481101593.0Topological domainLumenal
HgeneCANXchr5:179134191chr5:179260032ENST00000504734+41521_481101593.0Topological domainLumenal
HgeneCANXchr5:179137066chr5:179260032ENST00000247461+71521_481240593.0Topological domainLumenal
HgeneCANXchr5:179137066chr5:179260032ENST00000452673+71521_481240593.0Topological domainLumenal
HgeneCANXchr5:179137066chr5:179260032ENST00000504734+71521_481240593.0Topological domainLumenal
HgeneCANXchr5:179134191chr5:179260032ENST00000247461+415482_502101593.0TransmembraneHelical
HgeneCANXchr5:179134191chr5:179260032ENST00000452673+415482_502101593.0TransmembraneHelical
HgeneCANXchr5:179134191chr5:179260032ENST00000504734+415482_502101593.0TransmembraneHelical
HgeneCANXchr5:179137066chr5:179260032ENST00000247461+715482_502240593.0TransmembraneHelical
HgeneCANXchr5:179137066chr5:179260032ENST00000452673+715482_502240593.0TransmembraneHelical
HgeneCANXchr5:179137066chr5:179260032ENST00000504734+715482_502240593.0TransmembraneHelical
TgeneSQSTM1chr5:179134191chr5:179260032ENST00000360718373_102167357.0DomainPB1
TgeneSQSTM1chr5:179134191chr5:179260032ENST00000376929593_102167357.0DomainPB1
TgeneSQSTM1chr5:179134191chr5:179260032ENST00000389805483_102251441.0DomainPB1
TgeneSQSTM1chr5:179134191chr5:179260032ENST00000402874483_102167357.0DomainPB1
TgeneSQSTM1chr5:179137066chr5:179260032ENST00000360718373_102167357.0DomainPB1
TgeneSQSTM1chr5:179137066chr5:179260032ENST00000376929593_102167357.0DomainPB1
TgeneSQSTM1chr5:179137066chr5:179260032ENST00000389805483_102251441.0DomainPB1
TgeneSQSTM1chr5:179137066chr5:179260032ENST00000402874483_102167357.0DomainPB1
TgeneSQSTM1chr5:179134191chr5:179260032ENST0000038980548228_233251441.0MotifNote=TRAF6-binding
TgeneSQSTM1chr5:179137066chr5:179260032ENST0000038980548228_233251441.0MotifNote=TRAF6-binding
TgeneSQSTM1chr5:179134191chr5:179260032ENST0000038980548170_220251441.0RegionNote=LIM protein-binding (LB)
TgeneSQSTM1chr5:179137066chr5:179260032ENST0000038980548170_220251441.0RegionNote=LIM protein-binding (LB)
TgeneSQSTM1chr5:179134191chr5:179260032ENST0000036071837122_167167357.0Zinc fingerZZ-type
TgeneSQSTM1chr5:179134191chr5:179260032ENST0000037692959122_167167357.0Zinc fingerZZ-type
TgeneSQSTM1chr5:179134191chr5:179260032ENST0000038980548122_167251441.0Zinc fingerZZ-type
TgeneSQSTM1chr5:179134191chr5:179260032ENST0000040287448122_167167357.0Zinc fingerZZ-type
TgeneSQSTM1chr5:179137066chr5:179260032ENST0000036071837122_167167357.0Zinc fingerZZ-type
TgeneSQSTM1chr5:179137066chr5:179260032ENST0000037692959122_167167357.0Zinc fingerZZ-type
TgeneSQSTM1chr5:179137066chr5:179260032ENST0000038980548122_167251441.0Zinc fingerZZ-type
TgeneSQSTM1chr5:179137066chr5:179260032ENST0000040287448122_167167357.0Zinc fingerZZ-type


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Fusion Gene Sequence for CANX-SQSTM1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>12806_12806_1_CANX-SQSTM1_CANX_chr5_179134191_ENST00000247461_SQSTM1_chr5_179260032_ENST00000376929_length(transcript)=2555nt_BP=504nt
ACTCAGGGGCCAGGGGCGGGCACAGGGCCGGGCTTCGTGCGGTGGGGCTCGCTCGCGCGGCAGCGGTGGCCGAGGCCTCTTGGTTCTGCG
GCACGTGACGGTCGGGCCGCCTCCGCCTCTCTCTTTACTGCGGCGCGGGGCAAGGTGTGCGGGCGGGAAGGGGCACGGGCACCCCCGCGG
TCCCCGGGAGGCTAGAGATCATGGAAGGGAAGTGGTTGCTGTGTATGTTACTGGTGCTTGGAACTGCTATTGTTGAGGCTCATGATGGAC
ATGATGATGATGTGATTGATATTGAGGATGACCTTGACGATGTCATTGAAGAGGTAGAAGACTCAAAACCAGATACCACTGCTCCTCCTT
CATCTCCCAAGGTTACTTACAAAGCTCCAGTTCCAACAGGGGAAGTATATTTTGCTGATTCTTTTGACAGAGGAACTCTGTCAGGGTGGA
TTTTATCCAAAGCCAAGAAAGACGATACCGATGATGAAATTGCCAAATATGATGGCATTGAAGTTGATATCGATGTGGAGCACGGAGGGA
AAAGAAGCCGCCTGACCCCCGTCTCTCCAGAGAGTTCCAGCACAGAGGAGAAGAGCAGCTCACAGCCAAGCAGCTGCTGCTCTGACCCCA
GCAAGCCGGGTGGGAATGTTGAGGGCGCCACGCAGTCTCTGGCGGAGCAGATGAGGAAGATCGCCTTGGAGTCCGAGGGGCGCCCTGAGG
AACAGATGGAGTCGGATAACTGTTCAGGAGGAGATGATGACTGGACCCATCTGTCTTCAAAAGAAGTGGACCCGTCTACAGGTGAACTCC
AGTCCCTACAGATGCCAGAATCCGAAGGGCCAAGCTCTCTGGACCCCTCCCAGGAGGGACCCACAGGGCTGAAGGAAGCTGCCTTGTACC
CACATCTCCCGCCAGAGGCTGACCCGCGGCTGATTGAGTCCCTCTCCCAGATGCTGTCCATGGGCTTCTCTGATGAAGGCGGCTGGCTCA
CCAGGCTCCTGCAGACCAAGAACTATGACATCGGAGCGGCTCTGGACACCATCCAGTATTCAAAGCATCCCCCGCCGTTGTGACCACTTT
TGCCCACCTCTTCTGCGTGCCCCTCTTCTGTCTCATAGTTGTGTTAAGCTTGCGTAGAATTGCAGGTCTCTGTACGGGCCAGTTTCTCTG
CCTTCTTCCAGGATCAGGGGTTAGGGTGCAAGAAGCCATTTAGGGCAGCAAAACAAGTGACATGAAGGGAGGGTCCCTGTGTGTGTGTGT
GCTGATGTTTCCTGGGTGCCCTGGCTCCTTGCAGCAGGGCTGGGCCTGCGAGACCCAAGGCTCACTGCAGCGCGCTCCTGACCCCTCCCT
GCAGGGGCTACGTTAGCAGCCCAGCACATAGCTTGCCTAATGGCTTTCACTTTCTCTTTTGTTTTAAATGACTCATAGGTCCCTGACATT
TAGTTGATTATTTTCTGCTACAGACCTGGTACACTCTGATTTTAGATAAAGTAAGCCTAGGTGTTGTCAGCAGGCAGGCTGGGGAGGCCA
GTGTTGTGGGCTTCCTGCTGGGACTGAGAAGGCTCACGAAGGGCATCCGCAATGTTGGTTTCACTGAGAGCTGCCTCCTGGTCTCTTCAC
CACTGTAGTTCTCTCATTTCCAAACCATCAGCTGCTTTTAAAATAAGATCTCTTTGTAGCCATCCTGTTAAATTTGTAAACAATCTAATT
AAATGGCATCAGCACTTTAACCAATGACGTTTGCATAGAGAGAAATGATTGACAGTAAGTTTATTGTTAATGGTTCTTACAGAGTATCTT
TAAAAGTGCCTTAGGGGAACCCTGTCCCTCCTAACAAGTGTATCTCGATTAATAACCTGCCAGTCCCAGATCACACATCATCATCGAAGT
CTTCCCCAGTTATAAAGAGGTCACATAGTCGTGTGGGTCGAGGATTCTGTGCCTCCAGGACCAGGGGCCCACCCTCTGCCCAGGGAGTCC
TTGCGTCCCATGAGGTCTTCCCGCAAGGCCTCTCAGACCCAGATGTGACGGGGTGTGTGGCCCGAGGAAGCTGGACAGCGGCAGTGGGCC
TGCTGAGGCCTTCTCTTGAGGCCTGTGCTCTGGGGGTCCCTTGCTTAGCCTGTGCTGGACCAGCTGGCCTGGGGTCCCTCTGAAGAGACC
TTGGCTGCTCACTGTCCACATGTGAACTTTTTCTAGGTGGCAGGACAAATTGCGCCCATTTAGAGGATGTGGCTGTAACCTGCTGGATGG
GACTCCATAGCTCCTTCCCAGGACCCCTCAGCTCCCCGGCACTGCAGTCTGCAGAGTTCTCCTGGAGGCAGGGGCTGCTGCCTTGTTTCA
CCTTCCATGTCAGGCCAGCCTGTCCCTGAAAGAGAAGATGGCCATGCCCTCCATGTGTAAGAACAATGCCAGGGCCCAGGAGGACCGCCT
GCCCTGCCTGGGCCTTGGCTGGGCCTCTGGTTCTGACACTTTCTGCTGGAAGCTGTCAGGCTGGGACAGGCTTTGATTTTGAGGGTTAGC

>12806_12806_1_CANX-SQSTM1_CANX_chr5_179134191_ENST00000247461_SQSTM1_chr5_179260032_ENST00000376929_length(amino acids)=290AA_BP=0
MEGKWLLCMLLVLGTAIVEAHDGHDDDVIDIEDDLDDVIEEVEDSKPDTTAPPSSPKVTYKAPVPTGEVYFADSFDRGTLSGWILSKAKK
DDTDDEIAKYDGIEVDIDVEHGGKRSRLTPVSPESSSTEEKSSSQPSSCCSDPSKPGGNVEGATQSLAEQMRKIALESEGRPEEQMESDN
CSGGDDDWTHLSSKEVDPSTGELQSLQMPESEGPSSLDPSQEGPTGLKEAALYPHLPPEADPRLIESLSQMLSMGFSDEGGWLTRLLQTK

--------------------------------------------------------------
>12806_12806_2_CANX-SQSTM1_CANX_chr5_179134191_ENST00000415618_SQSTM1_chr5_179260032_ENST00000376929_length(transcript)=2535nt_BP=484nt
AATCCGGCCAGGCGCTCGCGCTGGGTTCTGCTCACGCCCGTAGGGGCCCGCGTTCGCTGCAACGGGCCCTTCCTGATGGCCGATCGTCGG
ACTCCTACCCCTTTTGCCGGCTGCCGTTTGCCCCGTCAGCGAAGGGCGCGCGATGCGTCCCAAGTCTCGGCTCCAGGAACCAGACGGATC
ATGGAAGGGAAGTGGTTGCTGTGTATGTTACTGGTGCTTGGAACTGCTATTGTTGAGGCTCATGATGGACATGATGATGATGTGATTGAT
ATTGAGGATGACCTTGACGATGTCATTGAAGAGGTAGAAGACTCAAAACCAGATACCACTGCTCCTCCTTCATCTCCCAAGGTTACTTAC
AAAGCTCCAGTTCCAACAGGGGAAGTATATTTTGCTGATTCTTTTGACAGAGGAACTCTGTCAGGGTGGATTTTATCCAAAGCCAAGAAA
GACGATACCGATGATGAAATTGCCAAATATGATGGCATTGAAGTTGATATCGATGTGGAGCACGGAGGGAAAAGAAGCCGCCTGACCCCC
GTCTCTCCAGAGAGTTCCAGCACAGAGGAGAAGAGCAGCTCACAGCCAAGCAGCTGCTGCTCTGACCCCAGCAAGCCGGGTGGGAATGTT
GAGGGCGCCACGCAGTCTCTGGCGGAGCAGATGAGGAAGATCGCCTTGGAGTCCGAGGGGCGCCCTGAGGAACAGATGGAGTCGGATAAC
TGTTCAGGAGGAGATGATGACTGGACCCATCTGTCTTCAAAAGAAGTGGACCCGTCTACAGGTGAACTCCAGTCCCTACAGATGCCAGAA
TCCGAAGGGCCAAGCTCTCTGGACCCCTCCCAGGAGGGACCCACAGGGCTGAAGGAAGCTGCCTTGTACCCACATCTCCCGCCAGAGGCT
GACCCGCGGCTGATTGAGTCCCTCTCCCAGATGCTGTCCATGGGCTTCTCTGATGAAGGCGGCTGGCTCACCAGGCTCCTGCAGACCAAG
AACTATGACATCGGAGCGGCTCTGGACACCATCCAGTATTCAAAGCATCCCCCGCCGTTGTGACCACTTTTGCCCACCTCTTCTGCGTGC
CCCTCTTCTGTCTCATAGTTGTGTTAAGCTTGCGTAGAATTGCAGGTCTCTGTACGGGCCAGTTTCTCTGCCTTCTTCCAGGATCAGGGG
TTAGGGTGCAAGAAGCCATTTAGGGCAGCAAAACAAGTGACATGAAGGGAGGGTCCCTGTGTGTGTGTGTGCTGATGTTTCCTGGGTGCC
CTGGCTCCTTGCAGCAGGGCTGGGCCTGCGAGACCCAAGGCTCACTGCAGCGCGCTCCTGACCCCTCCCTGCAGGGGCTACGTTAGCAGC
CCAGCACATAGCTTGCCTAATGGCTTTCACTTTCTCTTTTGTTTTAAATGACTCATAGGTCCCTGACATTTAGTTGATTATTTTCTGCTA
CAGACCTGGTACACTCTGATTTTAGATAAAGTAAGCCTAGGTGTTGTCAGCAGGCAGGCTGGGGAGGCCAGTGTTGTGGGCTTCCTGCTG
GGACTGAGAAGGCTCACGAAGGGCATCCGCAATGTTGGTTTCACTGAGAGCTGCCTCCTGGTCTCTTCACCACTGTAGTTCTCTCATTTC
CAAACCATCAGCTGCTTTTAAAATAAGATCTCTTTGTAGCCATCCTGTTAAATTTGTAAACAATCTAATTAAATGGCATCAGCACTTTAA
CCAATGACGTTTGCATAGAGAGAAATGATTGACAGTAAGTTTATTGTTAATGGTTCTTACAGAGTATCTTTAAAAGTGCCTTAGGGGAAC
CCTGTCCCTCCTAACAAGTGTATCTCGATTAATAACCTGCCAGTCCCAGATCACACATCATCATCGAAGTCTTCCCCAGTTATAAAGAGG
TCACATAGTCGTGTGGGTCGAGGATTCTGTGCCTCCAGGACCAGGGGCCCACCCTCTGCCCAGGGAGTCCTTGCGTCCCATGAGGTCTTC
CCGCAAGGCCTCTCAGACCCAGATGTGACGGGGTGTGTGGCCCGAGGAAGCTGGACAGCGGCAGTGGGCCTGCTGAGGCCTTCTCTTGAG
GCCTGTGCTCTGGGGGTCCCTTGCTTAGCCTGTGCTGGACCAGCTGGCCTGGGGTCCCTCTGAAGAGACCTTGGCTGCTCACTGTCCACA
TGTGAACTTTTTCTAGGTGGCAGGACAAATTGCGCCCATTTAGAGGATGTGGCTGTAACCTGCTGGATGGGACTCCATAGCTCCTTCCCA
GGACCCCTCAGCTCCCCGGCACTGCAGTCTGCAGAGTTCTCCTGGAGGCAGGGGCTGCTGCCTTGTTTCACCTTCCATGTCAGGCCAGCC
TGTCCCTGAAAGAGAAGATGGCCATGCCCTCCATGTGTAAGAACAATGCCAGGGCCCAGGAGGACCGCCTGCCCTGCCTGGGCCTTGGCT
GGGCCTCTGGTTCTGACACTTTCTGCTGGAAGCTGTCAGGCTGGGACAGGCTTTGATTTTGAGGGTTAGCAAGACAAAGCAAATAAATGC

>12806_12806_2_CANX-SQSTM1_CANX_chr5_179134191_ENST00000415618_SQSTM1_chr5_179260032_ENST00000376929_length(amino acids)=341AA_BP=1
MLTPVGARVRCNGPFLMADRRTPTPFAGCRLPRQRRARDASQVSAPGTRRIMEGKWLLCMLLVLGTAIVEAHDGHDDDVIDIEDDLDDVI
EEVEDSKPDTTAPPSSPKVTYKAPVPTGEVYFADSFDRGTLSGWILSKAKKDDTDDEIAKYDGIEVDIDVEHGGKRSRLTPVSPESSSTE
EKSSSQPSSCCSDPSKPGGNVEGATQSLAEQMRKIALESEGRPEEQMESDNCSGGDDDWTHLSSKEVDPSTGELQSLQMPESEGPSSLDP

--------------------------------------------------------------
>12806_12806_3_CANX-SQSTM1_CANX_chr5_179134191_ENST00000452673_SQSTM1_chr5_179260032_ENST00000376929_length(transcript)=2502nt_BP=451nt
ACTCAGGGGCCAGGGGCGGGCACAGGGCCGGGCTTCGTGCGGTGGGGCTCGCTCGCGCGGCAGCGGTGGCCGAGGCCTCTTGGTTCTGCG
GCACGTGACGGTCGGGCCGCCTCCGCCTCTCTCTTTACTGCGGCGCGGGGCAAGATCATGGAAGGGAAGTGGTTGCTGTGTATGTTACTG
GTGCTTGGAACTGCTATTGTTGAGGCTCATGATGGACATGATGATGATGTGATTGATATTGAGGATGACCTTGACGATGTCATTGAAGAG
GTAGAAGACTCAAAACCAGATACCACTGCTCCTCCTTCATCTCCCAAGGTTACTTACAAAGCTCCAGTTCCAACAGGGGAAGTATATTTT
GCTGATTCTTTTGACAGAGGAACTCTGTCAGGGTGGATTTTATCCAAAGCCAAGAAAGACGATACCGATGATGAAATTGCCAAATATGAT
GGCATTGAAGTTGATATCGATGTGGAGCACGGAGGGAAAAGAAGCCGCCTGACCCCCGTCTCTCCAGAGAGTTCCAGCACAGAGGAGAAG
AGCAGCTCACAGCCAAGCAGCTGCTGCTCTGACCCCAGCAAGCCGGGTGGGAATGTTGAGGGCGCCACGCAGTCTCTGGCGGAGCAGATG
AGGAAGATCGCCTTGGAGTCCGAGGGGCGCCCTGAGGAACAGATGGAGTCGGATAACTGTTCAGGAGGAGATGATGACTGGACCCATCTG
TCTTCAAAAGAAGTGGACCCGTCTACAGGTGAACTCCAGTCCCTACAGATGCCAGAATCCGAAGGGCCAAGCTCTCTGGACCCCTCCCAG
GAGGGACCCACAGGGCTGAAGGAAGCTGCCTTGTACCCACATCTCCCGCCAGAGGCTGACCCGCGGCTGATTGAGTCCCTCTCCCAGATG
CTGTCCATGGGCTTCTCTGATGAAGGCGGCTGGCTCACCAGGCTCCTGCAGACCAAGAACTATGACATCGGAGCGGCTCTGGACACCATC
CAGTATTCAAAGCATCCCCCGCCGTTGTGACCACTTTTGCCCACCTCTTCTGCGTGCCCCTCTTCTGTCTCATAGTTGTGTTAAGCTTGC
GTAGAATTGCAGGTCTCTGTACGGGCCAGTTTCTCTGCCTTCTTCCAGGATCAGGGGTTAGGGTGCAAGAAGCCATTTAGGGCAGCAAAA
CAAGTGACATGAAGGGAGGGTCCCTGTGTGTGTGTGTGCTGATGTTTCCTGGGTGCCCTGGCTCCTTGCAGCAGGGCTGGGCCTGCGAGA
CCCAAGGCTCACTGCAGCGCGCTCCTGACCCCTCCCTGCAGGGGCTACGTTAGCAGCCCAGCACATAGCTTGCCTAATGGCTTTCACTTT
CTCTTTTGTTTTAAATGACTCATAGGTCCCTGACATTTAGTTGATTATTTTCTGCTACAGACCTGGTACACTCTGATTTTAGATAAAGTA
AGCCTAGGTGTTGTCAGCAGGCAGGCTGGGGAGGCCAGTGTTGTGGGCTTCCTGCTGGGACTGAGAAGGCTCACGAAGGGCATCCGCAAT
GTTGGTTTCACTGAGAGCTGCCTCCTGGTCTCTTCACCACTGTAGTTCTCTCATTTCCAAACCATCAGCTGCTTTTAAAATAAGATCTCT
TTGTAGCCATCCTGTTAAATTTGTAAACAATCTAATTAAATGGCATCAGCACTTTAACCAATGACGTTTGCATAGAGAGAAATGATTGAC
AGTAAGTTTATTGTTAATGGTTCTTACAGAGTATCTTTAAAAGTGCCTTAGGGGAACCCTGTCCCTCCTAACAAGTGTATCTCGATTAAT
AACCTGCCAGTCCCAGATCACACATCATCATCGAAGTCTTCCCCAGTTATAAAGAGGTCACATAGTCGTGTGGGTCGAGGATTCTGTGCC
TCCAGGACCAGGGGCCCACCCTCTGCCCAGGGAGTCCTTGCGTCCCATGAGGTCTTCCCGCAAGGCCTCTCAGACCCAGATGTGACGGGG
TGTGTGGCCCGAGGAAGCTGGACAGCGGCAGTGGGCCTGCTGAGGCCTTCTCTTGAGGCCTGTGCTCTGGGGGTCCCTTGCTTAGCCTGT
GCTGGACCAGCTGGCCTGGGGTCCCTCTGAAGAGACCTTGGCTGCTCACTGTCCACATGTGAACTTTTTCTAGGTGGCAGGACAAATTGC
GCCCATTTAGAGGATGTGGCTGTAACCTGCTGGATGGGACTCCATAGCTCCTTCCCAGGACCCCTCAGCTCCCCGGCACTGCAGTCTGCA
GAGTTCTCCTGGAGGCAGGGGCTGCTGCCTTGTTTCACCTTCCATGTCAGGCCAGCCTGTCCCTGAAAGAGAAGATGGCCATGCCCTCCA
TGTGTAAGAACAATGCCAGGGCCCAGGAGGACCGCCTGCCCTGCCTGGGCCTTGGCTGGGCCTCTGGTTCTGACACTTTCTGCTGGAAGC

>12806_12806_3_CANX-SQSTM1_CANX_chr5_179134191_ENST00000452673_SQSTM1_chr5_179260032_ENST00000376929_length(amino acids)=290AA_BP=0
MEGKWLLCMLLVLGTAIVEAHDGHDDDVIDIEDDLDDVIEEVEDSKPDTTAPPSSPKVTYKAPVPTGEVYFADSFDRGTLSGWILSKAKK
DDTDDEIAKYDGIEVDIDVEHGGKRSRLTPVSPESSSTEEKSSSQPSSCCSDPSKPGGNVEGATQSLAEQMRKIALESEGRPEEQMESDN
CSGGDDDWTHLSSKEVDPSTGELQSLQMPESEGPSSLDPSQEGPTGLKEAALYPHLPPEADPRLIESLSQMLSMGFSDEGGWLTRLLQTK

--------------------------------------------------------------
>12806_12806_4_CANX-SQSTM1_CANX_chr5_179134191_ENST00000504734_SQSTM1_chr5_179260032_ENST00000376929_length(transcript)=2545nt_BP=494nt
AGTGCACGCCAATCCGGCCAGGCGCTCGCGCTGGGTTCTGCTCACGCCCGTAGGGGCCCGCGTTCGCTGCAACGGGCCCTTCCTGATGGC
CGATCGTCGGACTCCTACCCCTTTTGCCGGCTGCCGTTTGCCCCGTCAGCGAAGGGCGCGCGATGCGTCCCAAGTCTCGGCTCCAGGAAC
CAGACGGATCATGGAAGGGAAGTGGTTGCTGTGTATGTTACTGGTGCTTGGAACTGCTATTGTTGAGGCTCATGATGGACATGATGATGA
TGTGATTGATATTGAGGATGACCTTGACGATGTCATTGAAGAGGTAGAAGACTCAAAACCAGATACCACTGCTCCTCCTTCATCTCCCAA
GGTTACTTACAAAGCTCCAGTTCCAACAGGGGAAGTATATTTTGCTGATTCTTTTGACAGAGGAACTCTGTCAGGGTGGATTTTATCCAA
AGCCAAGAAAGACGATACCGATGATGAAATTGCCAAATATGATGGCATTGAAGTTGATATCGATGTGGAGCACGGAGGGAAAAGAAGCCG
CCTGACCCCCGTCTCTCCAGAGAGTTCCAGCACAGAGGAGAAGAGCAGCTCACAGCCAAGCAGCTGCTGCTCTGACCCCAGCAAGCCGGG
TGGGAATGTTGAGGGCGCCACGCAGTCTCTGGCGGAGCAGATGAGGAAGATCGCCTTGGAGTCCGAGGGGCGCCCTGAGGAACAGATGGA
GTCGGATAACTGTTCAGGAGGAGATGATGACTGGACCCATCTGTCTTCAAAAGAAGTGGACCCGTCTACAGGTGAACTCCAGTCCCTACA
GATGCCAGAATCCGAAGGGCCAAGCTCTCTGGACCCCTCCCAGGAGGGACCCACAGGGCTGAAGGAAGCTGCCTTGTACCCACATCTCCC
GCCAGAGGCTGACCCGCGGCTGATTGAGTCCCTCTCCCAGATGCTGTCCATGGGCTTCTCTGATGAAGGCGGCTGGCTCACCAGGCTCCT
GCAGACCAAGAACTATGACATCGGAGCGGCTCTGGACACCATCCAGTATTCAAAGCATCCCCCGCCGTTGTGACCACTTTTGCCCACCTC
TTCTGCGTGCCCCTCTTCTGTCTCATAGTTGTGTTAAGCTTGCGTAGAATTGCAGGTCTCTGTACGGGCCAGTTTCTCTGCCTTCTTCCA
GGATCAGGGGTTAGGGTGCAAGAAGCCATTTAGGGCAGCAAAACAAGTGACATGAAGGGAGGGTCCCTGTGTGTGTGTGTGCTGATGTTT
CCTGGGTGCCCTGGCTCCTTGCAGCAGGGCTGGGCCTGCGAGACCCAAGGCTCACTGCAGCGCGCTCCTGACCCCTCCCTGCAGGGGCTA
CGTTAGCAGCCCAGCACATAGCTTGCCTAATGGCTTTCACTTTCTCTTTTGTTTTAAATGACTCATAGGTCCCTGACATTTAGTTGATTA
TTTTCTGCTACAGACCTGGTACACTCTGATTTTAGATAAAGTAAGCCTAGGTGTTGTCAGCAGGCAGGCTGGGGAGGCCAGTGTTGTGGG
CTTCCTGCTGGGACTGAGAAGGCTCACGAAGGGCATCCGCAATGTTGGTTTCACTGAGAGCTGCCTCCTGGTCTCTTCACCACTGTAGTT
CTCTCATTTCCAAACCATCAGCTGCTTTTAAAATAAGATCTCTTTGTAGCCATCCTGTTAAATTTGTAAACAATCTAATTAAATGGCATC
AGCACTTTAACCAATGACGTTTGCATAGAGAGAAATGATTGACAGTAAGTTTATTGTTAATGGTTCTTACAGAGTATCTTTAAAAGTGCC
TTAGGGGAACCCTGTCCCTCCTAACAAGTGTATCTCGATTAATAACCTGCCAGTCCCAGATCACACATCATCATCGAAGTCTTCCCCAGT
TATAAAGAGGTCACATAGTCGTGTGGGTCGAGGATTCTGTGCCTCCAGGACCAGGGGCCCACCCTCTGCCCAGGGAGTCCTTGCGTCCCA
TGAGGTCTTCCCGCAAGGCCTCTCAGACCCAGATGTGACGGGGTGTGTGGCCCGAGGAAGCTGGACAGCGGCAGTGGGCCTGCTGAGGCC
TTCTCTTGAGGCCTGTGCTCTGGGGGTCCCTTGCTTAGCCTGTGCTGGACCAGCTGGCCTGGGGTCCCTCTGAAGAGACCTTGGCTGCTC
ACTGTCCACATGTGAACTTTTTCTAGGTGGCAGGACAAATTGCGCCCATTTAGAGGATGTGGCTGTAACCTGCTGGATGGGACTCCATAG
CTCCTTCCCAGGACCCCTCAGCTCCCCGGCACTGCAGTCTGCAGAGTTCTCCTGGAGGCAGGGGCTGCTGCCTTGTTTCACCTTCCATGT
CAGGCCAGCCTGTCCCTGAAAGAGAAGATGGCCATGCCCTCCATGTGTAAGAACAATGCCAGGGCCCAGGAGGACCGCCTGCCCTGCCTG
GGCCTTGGCTGGGCCTCTGGTTCTGACACTTTCTGCTGGAAGCTGTCAGGCTGGGACAGGCTTTGATTTTGAGGGTTAGCAAGACAAAGC

>12806_12806_4_CANX-SQSTM1_CANX_chr5_179134191_ENST00000504734_SQSTM1_chr5_179260032_ENST00000376929_length(amino acids)=341AA_BP=1
MLTPVGARVRCNGPFLMADRRTPTPFAGCRLPRQRRARDASQVSAPGTRRIMEGKWLLCMLLVLGTAIVEAHDGHDDDVIDIEDDLDDVI
EEVEDSKPDTTAPPSSPKVTYKAPVPTGEVYFADSFDRGTLSGWILSKAKKDDTDDEIAKYDGIEVDIDVEHGGKRSRLTPVSPESSSTE
EKSSSQPSSCCSDPSKPGGNVEGATQSLAEQMRKIALESEGRPEEQMESDNCSGGDDDWTHLSSKEVDPSTGELQSLQMPESEGPSSLDP

--------------------------------------------------------------
>12806_12806_5_CANX-SQSTM1_CANX_chr5_179137066_ENST00000247461_SQSTM1_chr5_179260032_ENST00000376929_length(transcript)=2972nt_BP=921nt
ACTCAGGGGCCAGGGGCGGGCACAGGGCCGGGCTTCGTGCGGTGGGGCTCGCTCGCGCGGCAGCGGTGGCCGAGGCCTCTTGGTTCTGCG
GCACGTGACGGTCGGGCCGCCTCCGCCTCTCTCTTTACTGCGGCGCGGGGCAAGGTGTGCGGGCGGGAAGGGGCACGGGCACCCCCGCGG
TCCCCGGGAGGCTAGAGATCATGGAAGGGAAGTGGTTGCTGTGTATGTTACTGGTGCTTGGAACTGCTATTGTTGAGGCTCATGATGGAC
ATGATGATGATGTGATTGATATTGAGGATGACCTTGACGATGTCATTGAAGAGGTAGAAGACTCAAAACCAGATACCACTGCTCCTCCTT
CATCTCCCAAGGTTACTTACAAAGCTCCAGTTCCAACAGGGGAAGTATATTTTGCTGATTCTTTTGACAGAGGAACTCTGTCAGGGTGGA
TTTTATCCAAAGCCAAGAAAGACGATACCGATGATGAAATTGCCAAATATGATGGAAAGTGGGAGGTAGAGGAAATGAAGGAGTCAAAGC
TTCCAGGTGATAAAGGACTTGTGTTGATGTCTCGGGCCAAGCATCATGCCATCTCTGCTAAACTGAACAAGCCCTTCCTGTTTGACACCA
AGCCTCTCATTGTTCAGTATGAGGTTAATTTCCAAAATGGAATAGAATGTGGTGGTGCCTATGTGAAACTGCTTTCTAAAACACCAGAAC
TCAACCTGGATCAGTTCCATGACAAGACCCCTTATACGATTATGTTTGGTCCAGATAAATGTGGAGAGGACTATAAACTGCACTTCATCT
TCCGACACAAAAACCCCAAAACGGGTATCTATGAAGAAAAACATGCTAAGAGGCCAGATGCAGATCTGAAGACCTATTTTACTGATAAGA
AAACACATCTTTACACACTAAGCATTGAAGTTGATATCGATGTGGAGCACGGAGGGAAAAGAAGCCGCCTGACCCCCGTCTCTCCAGAGA
GTTCCAGCACAGAGGAGAAGAGCAGCTCACAGCCAAGCAGCTGCTGCTCTGACCCCAGCAAGCCGGGTGGGAATGTTGAGGGCGCCACGC
AGTCTCTGGCGGAGCAGATGAGGAAGATCGCCTTGGAGTCCGAGGGGCGCCCTGAGGAACAGATGGAGTCGGATAACTGTTCAGGAGGAG
ATGATGACTGGACCCATCTGTCTTCAAAAGAAGTGGACCCGTCTACAGGTGAACTCCAGTCCCTACAGATGCCAGAATCCGAAGGGCCAA
GCTCTCTGGACCCCTCCCAGGAGGGACCCACAGGGCTGAAGGAAGCTGCCTTGTACCCACATCTCCCGCCAGAGGCTGACCCGCGGCTGA
TTGAGTCCCTCTCCCAGATGCTGTCCATGGGCTTCTCTGATGAAGGCGGCTGGCTCACCAGGCTCCTGCAGACCAAGAACTATGACATCG
GAGCGGCTCTGGACACCATCCAGTATTCAAAGCATCCCCCGCCGTTGTGACCACTTTTGCCCACCTCTTCTGCGTGCCCCTCTTCTGTCT
CATAGTTGTGTTAAGCTTGCGTAGAATTGCAGGTCTCTGTACGGGCCAGTTTCTCTGCCTTCTTCCAGGATCAGGGGTTAGGGTGCAAGA
AGCCATTTAGGGCAGCAAAACAAGTGACATGAAGGGAGGGTCCCTGTGTGTGTGTGTGCTGATGTTTCCTGGGTGCCCTGGCTCCTTGCA
GCAGGGCTGGGCCTGCGAGACCCAAGGCTCACTGCAGCGCGCTCCTGACCCCTCCCTGCAGGGGCTACGTTAGCAGCCCAGCACATAGCT
TGCCTAATGGCTTTCACTTTCTCTTTTGTTTTAAATGACTCATAGGTCCCTGACATTTAGTTGATTATTTTCTGCTACAGACCTGGTACA
CTCTGATTTTAGATAAAGTAAGCCTAGGTGTTGTCAGCAGGCAGGCTGGGGAGGCCAGTGTTGTGGGCTTCCTGCTGGGACTGAGAAGGC
TCACGAAGGGCATCCGCAATGTTGGTTTCACTGAGAGCTGCCTCCTGGTCTCTTCACCACTGTAGTTCTCTCATTTCCAAACCATCAGCT
GCTTTTAAAATAAGATCTCTTTGTAGCCATCCTGTTAAATTTGTAAACAATCTAATTAAATGGCATCAGCACTTTAACCAATGACGTTTG
CATAGAGAGAAATGATTGACAGTAAGTTTATTGTTAATGGTTCTTACAGAGTATCTTTAAAAGTGCCTTAGGGGAACCCTGTCCCTCCTA
ACAAGTGTATCTCGATTAATAACCTGCCAGTCCCAGATCACACATCATCATCGAAGTCTTCCCCAGTTATAAAGAGGTCACATAGTCGTG
TGGGTCGAGGATTCTGTGCCTCCAGGACCAGGGGCCCACCCTCTGCCCAGGGAGTCCTTGCGTCCCATGAGGTCTTCCCGCAAGGCCTCT
CAGACCCAGATGTGACGGGGTGTGTGGCCCGAGGAAGCTGGACAGCGGCAGTGGGCCTGCTGAGGCCTTCTCTTGAGGCCTGTGCTCTGG
GGGTCCCTTGCTTAGCCTGTGCTGGACCAGCTGGCCTGGGGTCCCTCTGAAGAGACCTTGGCTGCTCACTGTCCACATGTGAACTTTTTC
TAGGTGGCAGGACAAATTGCGCCCATTTAGAGGATGTGGCTGTAACCTGCTGGATGGGACTCCATAGCTCCTTCCCAGGACCCCTCAGCT
CCCCGGCACTGCAGTCTGCAGAGTTCTCCTGGAGGCAGGGGCTGCTGCCTTGTTTCACCTTCCATGTCAGGCCAGCCTGTCCCTGAAAGA
GAAGATGGCCATGCCCTCCATGTGTAAGAACAATGCCAGGGCCCAGGAGGACCGCCTGCCCTGCCTGGGCCTTGGCTGGGCCTCTGGTTC
TGACACTTTCTGCTGGAAGCTGTCAGGCTGGGACAGGCTTTGATTTTGAGGGTTAGCAAGACAAAGCAAATAAATGCCTTCCACCTCACC

>12806_12806_5_CANX-SQSTM1_CANX_chr5_179137066_ENST00000247461_SQSTM1_chr5_179260032_ENST00000376929_length(amino acids)=429AA_BP=0
MEGKWLLCMLLVLGTAIVEAHDGHDDDVIDIEDDLDDVIEEVEDSKPDTTAPPSSPKVTYKAPVPTGEVYFADSFDRGTLSGWILSKAKK
DDTDDEIAKYDGKWEVEEMKESKLPGDKGLVLMSRAKHHAISAKLNKPFLFDTKPLIVQYEVNFQNGIECGGAYVKLLSKTPELNLDQFH
DKTPYTIMFGPDKCGEDYKLHFIFRHKNPKTGIYEEKHAKRPDADLKTYFTDKKTHLYTLSIEVDIDVEHGGKRSRLTPVSPESSSTEEK
SSSQPSSCCSDPSKPGGNVEGATQSLAEQMRKIALESEGRPEEQMESDNCSGGDDDWTHLSSKEVDPSTGELQSLQMPESEGPSSLDPSQ

--------------------------------------------------------------
>12806_12806_6_CANX-SQSTM1_CANX_chr5_179137066_ENST00000415618_SQSTM1_chr5_179260032_ENST00000376929_length(transcript)=2952nt_BP=901nt
AATCCGGCCAGGCGCTCGCGCTGGGTTCTGCTCACGCCCGTAGGGGCCCGCGTTCGCTGCAACGGGCCCTTCCTGATGGCCGATCGTCGG
ACTCCTACCCCTTTTGCCGGCTGCCGTTTGCCCCGTCAGCGAAGGGCGCGCGATGCGTCCCAAGTCTCGGCTCCAGGAACCAGACGGATC
ATGGAAGGGAAGTGGTTGCTGTGTATGTTACTGGTGCTTGGAACTGCTATTGTTGAGGCTCATGATGGACATGATGATGATGTGATTGAT
ATTGAGGATGACCTTGACGATGTCATTGAAGAGGTAGAAGACTCAAAACCAGATACCACTGCTCCTCCTTCATCTCCCAAGGTTACTTAC
AAAGCTCCAGTTCCAACAGGGGAAGTATATTTTGCTGATTCTTTTGACAGAGGAACTCTGTCAGGGTGGATTTTATCCAAAGCCAAGAAA
GACGATACCGATGATGAAATTGCCAAATATGATGGAAAGTGGGAGGTAGAGGAAATGAAGGAGTCAAAGCTTCCAGGTGATAAAGGACTT
GTGTTGATGTCTCGGGCCAAGCATCATGCCATCTCTGCTAAACTGAACAAGCCCTTCCTGTTTGACACCAAGCCTCTCATTGTTCAGTAT
GAGGTTAATTTCCAAAATGGAATAGAATGTGGTGGTGCCTATGTGAAACTGCTTTCTAAAACACCAGAACTCAACCTGGATCAGTTCCAT
GACAAGACCCCTTATACGATTATGTTTGGTCCAGATAAATGTGGAGAGGACTATAAACTGCACTTCATCTTCCGACACAAAAACCCCAAA
ACGGGTATCTATGAAGAAAAACATGCTAAGAGGCCAGATGCAGATCTGAAGACCTATTTTACTGATAAGAAAACACATCTTTACACACTA
AGCATTGAAGTTGATATCGATGTGGAGCACGGAGGGAAAAGAAGCCGCCTGACCCCCGTCTCTCCAGAGAGTTCCAGCACAGAGGAGAAG
AGCAGCTCACAGCCAAGCAGCTGCTGCTCTGACCCCAGCAAGCCGGGTGGGAATGTTGAGGGCGCCACGCAGTCTCTGGCGGAGCAGATG
AGGAAGATCGCCTTGGAGTCCGAGGGGCGCCCTGAGGAACAGATGGAGTCGGATAACTGTTCAGGAGGAGATGATGACTGGACCCATCTG
TCTTCAAAAGAAGTGGACCCGTCTACAGGTGAACTCCAGTCCCTACAGATGCCAGAATCCGAAGGGCCAAGCTCTCTGGACCCCTCCCAG
GAGGGACCCACAGGGCTGAAGGAAGCTGCCTTGTACCCACATCTCCCGCCAGAGGCTGACCCGCGGCTGATTGAGTCCCTCTCCCAGATG
CTGTCCATGGGCTTCTCTGATGAAGGCGGCTGGCTCACCAGGCTCCTGCAGACCAAGAACTATGACATCGGAGCGGCTCTGGACACCATC
CAGTATTCAAAGCATCCCCCGCCGTTGTGACCACTTTTGCCCACCTCTTCTGCGTGCCCCTCTTCTGTCTCATAGTTGTGTTAAGCTTGC
GTAGAATTGCAGGTCTCTGTACGGGCCAGTTTCTCTGCCTTCTTCCAGGATCAGGGGTTAGGGTGCAAGAAGCCATTTAGGGCAGCAAAA
CAAGTGACATGAAGGGAGGGTCCCTGTGTGTGTGTGTGCTGATGTTTCCTGGGTGCCCTGGCTCCTTGCAGCAGGGCTGGGCCTGCGAGA
CCCAAGGCTCACTGCAGCGCGCTCCTGACCCCTCCCTGCAGGGGCTACGTTAGCAGCCCAGCACATAGCTTGCCTAATGGCTTTCACTTT
CTCTTTTGTTTTAAATGACTCATAGGTCCCTGACATTTAGTTGATTATTTTCTGCTACAGACCTGGTACACTCTGATTTTAGATAAAGTA
AGCCTAGGTGTTGTCAGCAGGCAGGCTGGGGAGGCCAGTGTTGTGGGCTTCCTGCTGGGACTGAGAAGGCTCACGAAGGGCATCCGCAAT
GTTGGTTTCACTGAGAGCTGCCTCCTGGTCTCTTCACCACTGTAGTTCTCTCATTTCCAAACCATCAGCTGCTTTTAAAATAAGATCTCT
TTGTAGCCATCCTGTTAAATTTGTAAACAATCTAATTAAATGGCATCAGCACTTTAACCAATGACGTTTGCATAGAGAGAAATGATTGAC
AGTAAGTTTATTGTTAATGGTTCTTACAGAGTATCTTTAAAAGTGCCTTAGGGGAACCCTGTCCCTCCTAACAAGTGTATCTCGATTAAT
AACCTGCCAGTCCCAGATCACACATCATCATCGAAGTCTTCCCCAGTTATAAAGAGGTCACATAGTCGTGTGGGTCGAGGATTCTGTGCC
TCCAGGACCAGGGGCCCACCCTCTGCCCAGGGAGTCCTTGCGTCCCATGAGGTCTTCCCGCAAGGCCTCTCAGACCCAGATGTGACGGGG
TGTGTGGCCCGAGGAAGCTGGACAGCGGCAGTGGGCCTGCTGAGGCCTTCTCTTGAGGCCTGTGCTCTGGGGGTCCCTTGCTTAGCCTGT
GCTGGACCAGCTGGCCTGGGGTCCCTCTGAAGAGACCTTGGCTGCTCACTGTCCACATGTGAACTTTTTCTAGGTGGCAGGACAAATTGC
GCCCATTTAGAGGATGTGGCTGTAACCTGCTGGATGGGACTCCATAGCTCCTTCCCAGGACCCCTCAGCTCCCCGGCACTGCAGTCTGCA
GAGTTCTCCTGGAGGCAGGGGCTGCTGCCTTGTTTCACCTTCCATGTCAGGCCAGCCTGTCCCTGAAAGAGAAGATGGCCATGCCCTCCA
TGTGTAAGAACAATGCCAGGGCCCAGGAGGACCGCCTGCCCTGCCTGGGCCTTGGCTGGGCCTCTGGTTCTGACACTTTCTGCTGGAAGC

>12806_12806_6_CANX-SQSTM1_CANX_chr5_179137066_ENST00000415618_SQSTM1_chr5_179260032_ENST00000376929_length(amino acids)=480AA_BP=1
MLTPVGARVRCNGPFLMADRRTPTPFAGCRLPRQRRARDASQVSAPGTRRIMEGKWLLCMLLVLGTAIVEAHDGHDDDVIDIEDDLDDVI
EEVEDSKPDTTAPPSSPKVTYKAPVPTGEVYFADSFDRGTLSGWILSKAKKDDTDDEIAKYDGKWEVEEMKESKLPGDKGLVLMSRAKHH
AISAKLNKPFLFDTKPLIVQYEVNFQNGIECGGAYVKLLSKTPELNLDQFHDKTPYTIMFGPDKCGEDYKLHFIFRHKNPKTGIYEEKHA
KRPDADLKTYFTDKKTHLYTLSIEVDIDVEHGGKRSRLTPVSPESSSTEEKSSSQPSSCCSDPSKPGGNVEGATQSLAEQMRKIALESEG
RPEEQMESDNCSGGDDDWTHLSSKEVDPSTGELQSLQMPESEGPSSLDPSQEGPTGLKEAALYPHLPPEADPRLIESLSQMLSMGFSDEG

--------------------------------------------------------------
>12806_12806_7_CANX-SQSTM1_CANX_chr5_179137066_ENST00000452673_SQSTM1_chr5_179260032_ENST00000376929_length(transcript)=2919nt_BP=868nt
ACTCAGGGGCCAGGGGCGGGCACAGGGCCGGGCTTCGTGCGGTGGGGCTCGCTCGCGCGGCAGCGGTGGCCGAGGCCTCTTGGTTCTGCG
GCACGTGACGGTCGGGCCGCCTCCGCCTCTCTCTTTACTGCGGCGCGGGGCAAGATCATGGAAGGGAAGTGGTTGCTGTGTATGTTACTG
GTGCTTGGAACTGCTATTGTTGAGGCTCATGATGGACATGATGATGATGTGATTGATATTGAGGATGACCTTGACGATGTCATTGAAGAG
GTAGAAGACTCAAAACCAGATACCACTGCTCCTCCTTCATCTCCCAAGGTTACTTACAAAGCTCCAGTTCCAACAGGGGAAGTATATTTT
GCTGATTCTTTTGACAGAGGAACTCTGTCAGGGTGGATTTTATCCAAAGCCAAGAAAGACGATACCGATGATGAAATTGCCAAATATGAT
GGAAAGTGGGAGGTAGAGGAAATGAAGGAGTCAAAGCTTCCAGGTGATAAAGGACTTGTGTTGATGTCTCGGGCCAAGCATCATGCCATC
TCTGCTAAACTGAACAAGCCCTTCCTGTTTGACACCAAGCCTCTCATTGTTCAGTATGAGGTTAATTTCCAAAATGGAATAGAATGTGGT
GGTGCCTATGTGAAACTGCTTTCTAAAACACCAGAACTCAACCTGGATCAGTTCCATGACAAGACCCCTTATACGATTATGTTTGGTCCA
GATAAATGTGGAGAGGACTATAAACTGCACTTCATCTTCCGACACAAAAACCCCAAAACGGGTATCTATGAAGAAAAACATGCTAAGAGG
CCAGATGCAGATCTGAAGACCTATTTTACTGATAAGAAAACACATCTTTACACACTAAGCATTGAAGTTGATATCGATGTGGAGCACGGA
GGGAAAAGAAGCCGCCTGACCCCCGTCTCTCCAGAGAGTTCCAGCACAGAGGAGAAGAGCAGCTCACAGCCAAGCAGCTGCTGCTCTGAC
CCCAGCAAGCCGGGTGGGAATGTTGAGGGCGCCACGCAGTCTCTGGCGGAGCAGATGAGGAAGATCGCCTTGGAGTCCGAGGGGCGCCCT
GAGGAACAGATGGAGTCGGATAACTGTTCAGGAGGAGATGATGACTGGACCCATCTGTCTTCAAAAGAAGTGGACCCGTCTACAGGTGAA
CTCCAGTCCCTACAGATGCCAGAATCCGAAGGGCCAAGCTCTCTGGACCCCTCCCAGGAGGGACCCACAGGGCTGAAGGAAGCTGCCTTG
TACCCACATCTCCCGCCAGAGGCTGACCCGCGGCTGATTGAGTCCCTCTCCCAGATGCTGTCCATGGGCTTCTCTGATGAAGGCGGCTGG
CTCACCAGGCTCCTGCAGACCAAGAACTATGACATCGGAGCGGCTCTGGACACCATCCAGTATTCAAAGCATCCCCCGCCGTTGTGACCA
CTTTTGCCCACCTCTTCTGCGTGCCCCTCTTCTGTCTCATAGTTGTGTTAAGCTTGCGTAGAATTGCAGGTCTCTGTACGGGCCAGTTTC
TCTGCCTTCTTCCAGGATCAGGGGTTAGGGTGCAAGAAGCCATTTAGGGCAGCAAAACAAGTGACATGAAGGGAGGGTCCCTGTGTGTGT
GTGTGCTGATGTTTCCTGGGTGCCCTGGCTCCTTGCAGCAGGGCTGGGCCTGCGAGACCCAAGGCTCACTGCAGCGCGCTCCTGACCCCT
CCCTGCAGGGGCTACGTTAGCAGCCCAGCACATAGCTTGCCTAATGGCTTTCACTTTCTCTTTTGTTTTAAATGACTCATAGGTCCCTGA
CATTTAGTTGATTATTTTCTGCTACAGACCTGGTACACTCTGATTTTAGATAAAGTAAGCCTAGGTGTTGTCAGCAGGCAGGCTGGGGAG
GCCAGTGTTGTGGGCTTCCTGCTGGGACTGAGAAGGCTCACGAAGGGCATCCGCAATGTTGGTTTCACTGAGAGCTGCCTCCTGGTCTCT
TCACCACTGTAGTTCTCTCATTTCCAAACCATCAGCTGCTTTTAAAATAAGATCTCTTTGTAGCCATCCTGTTAAATTTGTAAACAATCT
AATTAAATGGCATCAGCACTTTAACCAATGACGTTTGCATAGAGAGAAATGATTGACAGTAAGTTTATTGTTAATGGTTCTTACAGAGTA
TCTTTAAAAGTGCCTTAGGGGAACCCTGTCCCTCCTAACAAGTGTATCTCGATTAATAACCTGCCAGTCCCAGATCACACATCATCATCG
AAGTCTTCCCCAGTTATAAAGAGGTCACATAGTCGTGTGGGTCGAGGATTCTGTGCCTCCAGGACCAGGGGCCCACCCTCTGCCCAGGGA
GTCCTTGCGTCCCATGAGGTCTTCCCGCAAGGCCTCTCAGACCCAGATGTGACGGGGTGTGTGGCCCGAGGAAGCTGGACAGCGGCAGTG
GGCCTGCTGAGGCCTTCTCTTGAGGCCTGTGCTCTGGGGGTCCCTTGCTTAGCCTGTGCTGGACCAGCTGGCCTGGGGTCCCTCTGAAGA
GACCTTGGCTGCTCACTGTCCACATGTGAACTTTTTCTAGGTGGCAGGACAAATTGCGCCCATTTAGAGGATGTGGCTGTAACCTGCTGG
ATGGGACTCCATAGCTCCTTCCCAGGACCCCTCAGCTCCCCGGCACTGCAGTCTGCAGAGTTCTCCTGGAGGCAGGGGCTGCTGCCTTGT
TTCACCTTCCATGTCAGGCCAGCCTGTCCCTGAAAGAGAAGATGGCCATGCCCTCCATGTGTAAGAACAATGCCAGGGCCCAGGAGGACC
GCCTGCCCTGCCTGGGCCTTGGCTGGGCCTCTGGTTCTGACACTTTCTGCTGGAAGCTGTCAGGCTGGGACAGGCTTTGATTTTGAGGGT

>12806_12806_7_CANX-SQSTM1_CANX_chr5_179137066_ENST00000452673_SQSTM1_chr5_179260032_ENST00000376929_length(amino acids)=429AA_BP=0
MEGKWLLCMLLVLGTAIVEAHDGHDDDVIDIEDDLDDVIEEVEDSKPDTTAPPSSPKVTYKAPVPTGEVYFADSFDRGTLSGWILSKAKK
DDTDDEIAKYDGKWEVEEMKESKLPGDKGLVLMSRAKHHAISAKLNKPFLFDTKPLIVQYEVNFQNGIECGGAYVKLLSKTPELNLDQFH
DKTPYTIMFGPDKCGEDYKLHFIFRHKNPKTGIYEEKHAKRPDADLKTYFTDKKTHLYTLSIEVDIDVEHGGKRSRLTPVSPESSSTEEK
SSSQPSSCCSDPSKPGGNVEGATQSLAEQMRKIALESEGRPEEQMESDNCSGGDDDWTHLSSKEVDPSTGELQSLQMPESEGPSSLDPSQ

--------------------------------------------------------------
>12806_12806_8_CANX-SQSTM1_CANX_chr5_179137066_ENST00000504734_SQSTM1_chr5_179260032_ENST00000376929_length(transcript)=2962nt_BP=911nt
AGTGCACGCCAATCCGGCCAGGCGCTCGCGCTGGGTTCTGCTCACGCCCGTAGGGGCCCGCGTTCGCTGCAACGGGCCCTTCCTGATGGC
CGATCGTCGGACTCCTACCCCTTTTGCCGGCTGCCGTTTGCCCCGTCAGCGAAGGGCGCGCGATGCGTCCCAAGTCTCGGCTCCAGGAAC
CAGACGGATCATGGAAGGGAAGTGGTTGCTGTGTATGTTACTGGTGCTTGGAACTGCTATTGTTGAGGCTCATGATGGACATGATGATGA
TGTGATTGATATTGAGGATGACCTTGACGATGTCATTGAAGAGGTAGAAGACTCAAAACCAGATACCACTGCTCCTCCTTCATCTCCCAA
GGTTACTTACAAAGCTCCAGTTCCAACAGGGGAAGTATATTTTGCTGATTCTTTTGACAGAGGAACTCTGTCAGGGTGGATTTTATCCAA
AGCCAAGAAAGACGATACCGATGATGAAATTGCCAAATATGATGGAAAGTGGGAGGTAGAGGAAATGAAGGAGTCAAAGCTTCCAGGTGA
TAAAGGACTTGTGTTGATGTCTCGGGCCAAGCATCATGCCATCTCTGCTAAACTGAACAAGCCCTTCCTGTTTGACACCAAGCCTCTCAT
TGTTCAGTATGAGGTTAATTTCCAAAATGGAATAGAATGTGGTGGTGCCTATGTGAAACTGCTTTCTAAAACACCAGAACTCAACCTGGA
TCAGTTCCATGACAAGACCCCTTATACGATTATGTTTGGTCCAGATAAATGTGGAGAGGACTATAAACTGCACTTCATCTTCCGACACAA
AAACCCCAAAACGGGTATCTATGAAGAAAAACATGCTAAGAGGCCAGATGCAGATCTGAAGACCTATTTTACTGATAAGAAAACACATCT
TTACACACTAAGCATTGAAGTTGATATCGATGTGGAGCACGGAGGGAAAAGAAGCCGCCTGACCCCCGTCTCTCCAGAGAGTTCCAGCAC
AGAGGAGAAGAGCAGCTCACAGCCAAGCAGCTGCTGCTCTGACCCCAGCAAGCCGGGTGGGAATGTTGAGGGCGCCACGCAGTCTCTGGC
GGAGCAGATGAGGAAGATCGCCTTGGAGTCCGAGGGGCGCCCTGAGGAACAGATGGAGTCGGATAACTGTTCAGGAGGAGATGATGACTG
GACCCATCTGTCTTCAAAAGAAGTGGACCCGTCTACAGGTGAACTCCAGTCCCTACAGATGCCAGAATCCGAAGGGCCAAGCTCTCTGGA
CCCCTCCCAGGAGGGACCCACAGGGCTGAAGGAAGCTGCCTTGTACCCACATCTCCCGCCAGAGGCTGACCCGCGGCTGATTGAGTCCCT
CTCCCAGATGCTGTCCATGGGCTTCTCTGATGAAGGCGGCTGGCTCACCAGGCTCCTGCAGACCAAGAACTATGACATCGGAGCGGCTCT
GGACACCATCCAGTATTCAAAGCATCCCCCGCCGTTGTGACCACTTTTGCCCACCTCTTCTGCGTGCCCCTCTTCTGTCTCATAGTTGTG
TTAAGCTTGCGTAGAATTGCAGGTCTCTGTACGGGCCAGTTTCTCTGCCTTCTTCCAGGATCAGGGGTTAGGGTGCAAGAAGCCATTTAG
GGCAGCAAAACAAGTGACATGAAGGGAGGGTCCCTGTGTGTGTGTGTGCTGATGTTTCCTGGGTGCCCTGGCTCCTTGCAGCAGGGCTGG
GCCTGCGAGACCCAAGGCTCACTGCAGCGCGCTCCTGACCCCTCCCTGCAGGGGCTACGTTAGCAGCCCAGCACATAGCTTGCCTAATGG
CTTTCACTTTCTCTTTTGTTTTAAATGACTCATAGGTCCCTGACATTTAGTTGATTATTTTCTGCTACAGACCTGGTACACTCTGATTTT
AGATAAAGTAAGCCTAGGTGTTGTCAGCAGGCAGGCTGGGGAGGCCAGTGTTGTGGGCTTCCTGCTGGGACTGAGAAGGCTCACGAAGGG
CATCCGCAATGTTGGTTTCACTGAGAGCTGCCTCCTGGTCTCTTCACCACTGTAGTTCTCTCATTTCCAAACCATCAGCTGCTTTTAAAA
TAAGATCTCTTTGTAGCCATCCTGTTAAATTTGTAAACAATCTAATTAAATGGCATCAGCACTTTAACCAATGACGTTTGCATAGAGAGA
AATGATTGACAGTAAGTTTATTGTTAATGGTTCTTACAGAGTATCTTTAAAAGTGCCTTAGGGGAACCCTGTCCCTCCTAACAAGTGTAT
CTCGATTAATAACCTGCCAGTCCCAGATCACACATCATCATCGAAGTCTTCCCCAGTTATAAAGAGGTCACATAGTCGTGTGGGTCGAGG
ATTCTGTGCCTCCAGGACCAGGGGCCCACCCTCTGCCCAGGGAGTCCTTGCGTCCCATGAGGTCTTCCCGCAAGGCCTCTCAGACCCAGA
TGTGACGGGGTGTGTGGCCCGAGGAAGCTGGACAGCGGCAGTGGGCCTGCTGAGGCCTTCTCTTGAGGCCTGTGCTCTGGGGGTCCCTTG
CTTAGCCTGTGCTGGACCAGCTGGCCTGGGGTCCCTCTGAAGAGACCTTGGCTGCTCACTGTCCACATGTGAACTTTTTCTAGGTGGCAG
GACAAATTGCGCCCATTTAGAGGATGTGGCTGTAACCTGCTGGATGGGACTCCATAGCTCCTTCCCAGGACCCCTCAGCTCCCCGGCACT
GCAGTCTGCAGAGTTCTCCTGGAGGCAGGGGCTGCTGCCTTGTTTCACCTTCCATGTCAGGCCAGCCTGTCCCTGAAAGAGAAGATGGCC
ATGCCCTCCATGTGTAAGAACAATGCCAGGGCCCAGGAGGACCGCCTGCCCTGCCTGGGCCTTGGCTGGGCCTCTGGTTCTGACACTTTC

>12806_12806_8_CANX-SQSTM1_CANX_chr5_179137066_ENST00000504734_SQSTM1_chr5_179260032_ENST00000376929_length(amino acids)=480AA_BP=1
MLTPVGARVRCNGPFLMADRRTPTPFAGCRLPRQRRARDASQVSAPGTRRIMEGKWLLCMLLVLGTAIVEAHDGHDDDVIDIEDDLDDVI
EEVEDSKPDTTAPPSSPKVTYKAPVPTGEVYFADSFDRGTLSGWILSKAKKDDTDDEIAKYDGKWEVEEMKESKLPGDKGLVLMSRAKHH
AISAKLNKPFLFDTKPLIVQYEVNFQNGIECGGAYVKLLSKTPELNLDQFHDKTPYTIMFGPDKCGEDYKLHFIFRHKNPKTGIYEEKHA
KRPDADLKTYFTDKKTHLYTLSIEVDIDVEHGGKRSRLTPVSPESSSTEEKSSSQPSSCCSDPSKPGGNVEGATQSLAEQMRKIALESEG
RPEEQMESDNCSGGDDDWTHLSSKEVDPSTGELQSLQMPESEGPSSLDPSQEGPTGLKEAALYPHLPPEADPRLIESLSQMLSMGFSDEG

--------------------------------------------------------------
>12806_12806_9_CANX-SQSTM1_CANX_chr5_179137066_ENST00000512607_SQSTM1_chr5_179260032_ENST00000376929_length(transcript)=2831nt_BP=780nt
GTTCTGCGGCACGTGACGGTCGGGCCGCCTCCGCCTCTCTCTTTACTGCGGCGCGGGGCAAGGTGTGCGGGCGGGAAGGGGCACGGGCAC
CCCCGCGGTCCCCGGGAGGCTAGAGATCATGGAAGGGAAGTGGTTGCTGTGTATGTTACTGGTGCTTGGAACTGCTATTGTTGAGGCTCA
TGATGGACATGATGATGATGTGATTGATATTGAGGATGACCTTGACGATGTCATTGAAGAGGTAGAAGACTCAAAACCAGATACCACTGC
TCCTCCTTCATCTCCCAAGGTTACTTACAAAGCTCCAGTTCCAACAGGGGAAGTATATTTTGCTGATTCTTTTGACAGAGGAACTCTGTC
AGGGAAAGTGGGAGGTAGAGGAAATGAAGGAGTCAAAGCTTCCAGGTGATAAAGGACTTGTGTTGATGTCTCGGGCCAAGCATCATGCCA
TCTCTGCTAAACTGAACAAGCCCTTCCTGTTTGACACCAAGCCTCTCATTGTTCAGTATGAGGTTAATTTCCAAAATGGAATAGAATGTG
GTGGTGCCTATGTGAAACTGCTTTCTAAAACACCAGAACTCAACCTGGATCAGTTCCATGACAAGACCCCTTATACGATTATGTTTGGTC
CAGATAAATGTGGAGAGGACTATAAACTGCACTTCATCTTCCGACACAAAAACCCCAAAACGGGTATCTATGAAGAAAAACATGCTAAGA
GGCCAGATGCAGATCTGAAGACCTATTTTACTGATAAGAAAACACATCTTTACACACTAAGCATTGAAGTTGATATCGATGTGGAGCACG
GAGGGAAAAGAAGCCGCCTGACCCCCGTCTCTCCAGAGAGTTCCAGCACAGAGGAGAAGAGCAGCTCACAGCCAAGCAGCTGCTGCTCTG
ACCCCAGCAAGCCGGGTGGGAATGTTGAGGGCGCCACGCAGTCTCTGGCGGAGCAGATGAGGAAGATCGCCTTGGAGTCCGAGGGGCGCC
CTGAGGAACAGATGGAGTCGGATAACTGTTCAGGAGGAGATGATGACTGGACCCATCTGTCTTCAAAAGAAGTGGACCCGTCTACAGGTG
AACTCCAGTCCCTACAGATGCCAGAATCCGAAGGGCCAAGCTCTCTGGACCCCTCCCAGGAGGGACCCACAGGGCTGAAGGAAGCTGCCT
TGTACCCACATCTCCCGCCAGAGGCTGACCCGCGGCTGATTGAGTCCCTCTCCCAGATGCTGTCCATGGGCTTCTCTGATGAAGGCGGCT
GGCTCACCAGGCTCCTGCAGACCAAGAACTATGACATCGGAGCGGCTCTGGACACCATCCAGTATTCAAAGCATCCCCCGCCGTTGTGAC
CACTTTTGCCCACCTCTTCTGCGTGCCCCTCTTCTGTCTCATAGTTGTGTTAAGCTTGCGTAGAATTGCAGGTCTCTGTACGGGCCAGTT
TCTCTGCCTTCTTCCAGGATCAGGGGTTAGGGTGCAAGAAGCCATTTAGGGCAGCAAAACAAGTGACATGAAGGGAGGGTCCCTGTGTGT
GTGTGTGCTGATGTTTCCTGGGTGCCCTGGCTCCTTGCAGCAGGGCTGGGCCTGCGAGACCCAAGGCTCACTGCAGCGCGCTCCTGACCC
CTCCCTGCAGGGGCTACGTTAGCAGCCCAGCACATAGCTTGCCTAATGGCTTTCACTTTCTCTTTTGTTTTAAATGACTCATAGGTCCCT
GACATTTAGTTGATTATTTTCTGCTACAGACCTGGTACACTCTGATTTTAGATAAAGTAAGCCTAGGTGTTGTCAGCAGGCAGGCTGGGG
AGGCCAGTGTTGTGGGCTTCCTGCTGGGACTGAGAAGGCTCACGAAGGGCATCCGCAATGTTGGTTTCACTGAGAGCTGCCTCCTGGTCT
CTTCACCACTGTAGTTCTCTCATTTCCAAACCATCAGCTGCTTTTAAAATAAGATCTCTTTGTAGCCATCCTGTTAAATTTGTAAACAAT
CTAATTAAATGGCATCAGCACTTTAACCAATGACGTTTGCATAGAGAGAAATGATTGACAGTAAGTTTATTGTTAATGGTTCTTACAGAG
TATCTTTAAAAGTGCCTTAGGGGAACCCTGTCCCTCCTAACAAGTGTATCTCGATTAATAACCTGCCAGTCCCAGATCACACATCATCAT
CGAAGTCTTCCCCAGTTATAAAGAGGTCACATAGTCGTGTGGGTCGAGGATTCTGTGCCTCCAGGACCAGGGGCCCACCCTCTGCCCAGG
GAGTCCTTGCGTCCCATGAGGTCTTCCCGCAAGGCCTCTCAGACCCAGATGTGACGGGGTGTGTGGCCCGAGGAAGCTGGACAGCGGCAG
TGGGCCTGCTGAGGCCTTCTCTTGAGGCCTGTGCTCTGGGGGTCCCTTGCTTAGCCTGTGCTGGACCAGCTGGCCTGGGGTCCCTCTGAA
GAGACCTTGGCTGCTCACTGTCCACATGTGAACTTTTTCTAGGTGGCAGGACAAATTGCGCCCATTTAGAGGATGTGGCTGTAACCTGCT
GGATGGGACTCCATAGCTCCTTCCCAGGACCCCTCAGCTCCCCGGCACTGCAGTCTGCAGAGTTCTCCTGGAGGCAGGGGCTGCTGCCTT
GTTTCACCTTCCATGTCAGGCCAGCCTGTCCCTGAAAGAGAAGATGGCCATGCCCTCCATGTGTAAGAACAATGCCAGGGCCCAGGAGGA
CCGCCTGCCCTGCCTGGGCCTTGGCTGGGCCTCTGGTTCTGACACTTTCTGCTGGAAGCTGTCAGGCTGGGACAGGCTTTGATTTTGAGG

>12806_12806_9_CANX-SQSTM1_CANX_chr5_179137066_ENST00000512607_SQSTM1_chr5_179260032_ENST00000376929_length(amino acids)=360AA_BP=1
MLLLHLPRLLTKLQFQQGKYILLILLTEELCQGKWEVEEMKESKLPGDKGLVLMSRAKHHAISAKLNKPFLFDTKPLIVQYEVNFQNGIE
CGGAYVKLLSKTPELNLDQFHDKTPYTIMFGPDKCGEDYKLHFIFRHKNPKTGIYEEKHAKRPDADLKTYFTDKKTHLYTLSIEVDIDVE
HGGKRSRLTPVSPESSSTEEKSSSQPSSCCSDPSKPGGNVEGATQSLAEQMRKIALESEGRPEEQMESDNCSGGDDDWTHLSSKEVDPST
GELQSLQMPESEGPSSLDPSQEGPTGLKEAALYPHLPPEADPRLIESLSQMLSMGFSDEGGWLTRLLQTKNYDIGAALDTIQYSKHPPPL

--------------------------------------------------------------

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Fusion Gene PPI Analysis for CANX-SQSTM1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneSQSTM1chr5:179134191chr5:179260032ENST0000036071837347_352167.33333333333334357.0KEAP1
TgeneSQSTM1chr5:179134191chr5:179260032ENST0000037692959347_352167.33333333333334357.0KEAP1
TgeneSQSTM1chr5:179134191chr5:179260032ENST0000038980548347_352251.33333333333334441.0KEAP1
TgeneSQSTM1chr5:179134191chr5:179260032ENST0000040287448347_352167.33333333333334357.0KEAP1
TgeneSQSTM1chr5:179137066chr5:179260032ENST0000036071837347_352167.33333333333334357.0KEAP1
TgeneSQSTM1chr5:179137066chr5:179260032ENST0000037692959347_352167.33333333333334357.0KEAP1
TgeneSQSTM1chr5:179137066chr5:179260032ENST0000038980548347_352251.33333333333334441.0KEAP1
TgeneSQSTM1chr5:179137066chr5:179260032ENST0000040287448347_352167.33333333333334357.0KEAP1
TgeneSQSTM1chr5:179134191chr5:179260032ENST0000036071837269_440167.33333333333334357.0NTRK1
TgeneSQSTM1chr5:179134191chr5:179260032ENST0000037692959269_440167.33333333333334357.0NTRK1
TgeneSQSTM1chr5:179134191chr5:179260032ENST0000038980548269_440251.33333333333334441.0NTRK1
TgeneSQSTM1chr5:179134191chr5:179260032ENST0000040287448269_440167.33333333333334357.0NTRK1
TgeneSQSTM1chr5:179137066chr5:179260032ENST0000036071837269_440167.33333333333334357.0NTRK1
TgeneSQSTM1chr5:179137066chr5:179260032ENST0000037692959269_440167.33333333333334357.0NTRK1
TgeneSQSTM1chr5:179137066chr5:179260032ENST0000038980548269_440251.33333333333334441.0NTRK1
TgeneSQSTM1chr5:179137066chr5:179260032ENST0000040287448269_440167.33333333333334357.0NTRK1


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneCANXchr5:179134191chr5:179260032ENST00000247461+415326_359101.33333333333333593.0PPIB
HgeneCANXchr5:179134191chr5:179260032ENST00000452673+415326_359101.33333333333333593.0PPIB
HgeneCANXchr5:179134191chr5:179260032ENST00000504734+415326_359101.33333333333333593.0PPIB
HgeneCANXchr5:179137066chr5:179260032ENST00000247461+715326_359240.33333333333334593.0PPIB
HgeneCANXchr5:179137066chr5:179260032ENST00000452673+715326_359240.33333333333334593.0PPIB
HgeneCANXchr5:179137066chr5:179260032ENST00000504734+715326_359240.33333333333334593.0PPIB
TgeneSQSTM1chr5:179134191chr5:179260032ENST0000036071837122_224167.33333333333334357.0GABRR3
TgeneSQSTM1chr5:179134191chr5:179260032ENST0000037692959122_224167.33333333333334357.0GABRR3
TgeneSQSTM1chr5:179134191chr5:179260032ENST0000038980548122_224251.33333333333334441.0GABRR3
TgeneSQSTM1chr5:179134191chr5:179260032ENST0000040287448122_224167.33333333333334357.0GABRR3
TgeneSQSTM1chr5:179137066chr5:179260032ENST0000036071837122_224167.33333333333334357.0GABRR3
TgeneSQSTM1chr5:179137066chr5:179260032ENST0000037692959122_224167.33333333333334357.0GABRR3
TgeneSQSTM1chr5:179137066chr5:179260032ENST0000038980548122_224251.33333333333334441.0GABRR3
TgeneSQSTM1chr5:179137066chr5:179260032ENST0000040287448122_224167.33333333333334357.0GABRR3
TgeneSQSTM1chr5:179134191chr5:179260032ENST00000360718372_50167.33333333333334357.0LCK
TgeneSQSTM1chr5:179134191chr5:179260032ENST00000376929592_50167.33333333333334357.0LCK
TgeneSQSTM1chr5:179134191chr5:179260032ENST00000389805482_50251.33333333333334441.0LCK
TgeneSQSTM1chr5:179134191chr5:179260032ENST00000402874482_50167.33333333333334357.0LCK
TgeneSQSTM1chr5:179137066chr5:179260032ENST00000360718372_50167.33333333333334357.0LCK
TgeneSQSTM1chr5:179137066chr5:179260032ENST00000376929592_50167.33333333333334357.0LCK
TgeneSQSTM1chr5:179137066chr5:179260032ENST00000389805482_50251.33333333333334441.0LCK
TgeneSQSTM1chr5:179137066chr5:179260032ENST00000402874482_50167.33333333333334357.0LCK
TgeneSQSTM1chr5:179134191chr5:179260032ENST000003607183750_80167.33333333333334357.0PAWR
TgeneSQSTM1chr5:179134191chr5:179260032ENST000003769295950_80167.33333333333334357.0PAWR
TgeneSQSTM1chr5:179134191chr5:179260032ENST000003898054850_80251.33333333333334441.0PAWR
TgeneSQSTM1chr5:179134191chr5:179260032ENST000004028744850_80167.33333333333334357.0PAWR
TgeneSQSTM1chr5:179137066chr5:179260032ENST000003607183750_80167.33333333333334357.0PAWR
TgeneSQSTM1chr5:179137066chr5:179260032ENST000003769295950_80167.33333333333334357.0PAWR
TgeneSQSTM1chr5:179137066chr5:179260032ENST000003898054850_80251.33333333333334441.0PAWR
TgeneSQSTM1chr5:179137066chr5:179260032ENST000004028744850_80167.33333333333334357.0PAWR
TgeneSQSTM1chr5:179134191chr5:179260032ENST000003607183743_107167.33333333333334357.0PRKCZ and dimerization
TgeneSQSTM1chr5:179134191chr5:179260032ENST000003769295943_107167.33333333333334357.0PRKCZ and dimerization
TgeneSQSTM1chr5:179134191chr5:179260032ENST000003898054843_107251.33333333333334441.0PRKCZ and dimerization
TgeneSQSTM1chr5:179134191chr5:179260032ENST000004028744843_107167.33333333333334357.0PRKCZ and dimerization
TgeneSQSTM1chr5:179137066chr5:179260032ENST000003607183743_107167.33333333333334357.0PRKCZ and dimerization
TgeneSQSTM1chr5:179137066chr5:179260032ENST000003769295943_107167.33333333333334357.0PRKCZ and dimerization
TgeneSQSTM1chr5:179137066chr5:179260032ENST000003898054843_107251.33333333333334441.0PRKCZ and dimerization
TgeneSQSTM1chr5:179137066chr5:179260032ENST000004028744843_107167.33333333333334357.0PRKCZ and dimerization


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CANX-SQSTM1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status
HgeneCANXP27824DB00031TenecteplaseBiotechApproved
HgeneCANXP27824DB11348Calcium PhosphateLigandSmall moleculeApproved
HgeneCANXP27824DB13999Moroctocog alfaChaperoneBiotechApproved
HgeneCANXP27824DB14481Calcium phosphate dihydrateSmall moleculeApproved
HgeneCANXP27824DB00025Antihemophilic factor, human recombinantChaperoneBiotechApproved|Investigational
HgeneCANXP27824DB11093Calcium citrateLigandSmall moleculeApproved|Investigational
HgeneCANXP27824DB13998Lonoctocog alfaChaperoneBiotechApproved|Investigational

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Related Diseases for CANX-SQSTM1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneCANXC0019193Hepatitis, Toxic1CTD_human
HgeneCANXC0151744Myocardial Ischemia1CTD_human
HgeneCANXC0860207Drug-Induced Liver Disease1CTD_human
HgeneCANXC1262760Hepatitis, Drug-Induced1CTD_human
HgeneCANXC3658290Drug-Induced Acute Liver Injury1CTD_human
HgeneCANXC4277682Chemical and Drug Induced Liver Injury1CTD_human
HgeneCANXC4279912Chemically-Induced Liver Toxicity1CTD_human
TgeneC4085252PAGET DISEASE OF BONE 39GENOMICS_ENGLAND;UNIPROT
TgeneC0002736Amyotrophic Lateral Sclerosis5CTD_human;ORPHANET
TgeneC4225326FRONTOTEMPORAL DEMENTIA AND/OR AMYOTROPHIC LATERAL SCLEROSIS 34CTD_human;UNIPROT
TgeneC0029463Osteosarcoma2GENOMICS_ENGLAND
TgeneC0221054Welander Distal Myopathy1ORPHANET
TgeneC0242383Age related macular degeneration1CTD_human
TgeneC0393554Amyotrophic Lateral Sclerosis With Dementia1CTD_human
TgeneC0543859Amyotrophic Lateral Sclerosis, Guam Form1CTD_human
TgeneC1853926NONAKA MYOPATHY1CTD_human;GENOMICS_ENGLAND
TgeneC2931290Welander distal myopathy, Swedish type1ORPHANET
TgeneC3888102Frontotemporal Dementia With Motor Neuron Disease1ORPHANET
TgeneC4011788Behavioral variant of frontotemporal dementia1ORPHANET