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in Kim Lab

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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:CAPNS1-NOMO2 (FusionGDB2 ID:HG826TG283820)

Fusion Gene Summary for CAPNS1-NOMO2

check button Fusion gene summary
Fusion gene informationFusion gene name: CAPNS1-NOMO2
Fusion gene ID: hg826tg283820
HgeneTgene
Gene symbol

CAPNS1

NOMO2

Gene ID

826

283820

Gene namecalpain small subunit 1NODAL modulator 2
SynonymsCALPAIN4|CANP|CANPS|CAPN4|CDPS|CSS1Nomo|PM5
Cytomap('CAPNS1')('NOMO2')

19q13.12

16p12.3

Type of geneprotein-codingprotein-coding
Descriptioncalpain small subunit 1CANP small subunitcalcium-activated neutral proteinase small subunitcalcium-dependent protease small subunit 1calcium-dependent protease, small subunitcalpain 4, small subunit (30K)calpain regulatory subunitcalpain, small polnodal modulator 2pM5 protein 2pM5 protein, centromeric copy
Modification date2020031320200313
UniProtAcc.

Q5JPE7

Ensembl transtripts involved in fusion geneENST00000589146, ENST00000246533, 
ENST00000587718, ENST00000588780, 
ENST00000588815, ENST00000590874, 
Fusion gene scores* DoF score29 X 25 X 9=65254 X 4 X 2=32
# samples 314
** MAII scorelog2(31/6525*10)=-4.39563778107037
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(4/32*10)=0.321928094887362
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: CAPNS1 [Title/Abstract] AND NOMO2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCAPNS1(36631950)-NOMO2(18532118), # samples:1
Anticipated loss of major functional domain due to fusion event.CAPNS1-NOMO2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
CAPNS1-NOMO2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across CAPNS1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across NOMO2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand


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Fusion Gene ORF analysis for CAPNS1-NOMO2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)
BP loci
(transcript)
Predicted start
(transcript)
Predicted stop
(transcript)
Seq length
(amino acids)

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000246533ENST00000330537CAPNS1chr1936631950+NOMO2chr1618532118-0.48442760.5155724
ENST00000246533ENST00000381474CAPNS1chr1936631950+NOMO2chr1618532118-0.481983570.51801646
ENST00000246533ENST00000543392CAPNS1chr1936631950+NOMO2chr1618532118-0.538017330.46198264
ENST00000587718ENST00000330537CAPNS1chr1936631950+NOMO2chr1618532118-0.848630250.15136983
ENST00000587718ENST00000381474CAPNS1chr1936631950+NOMO2chr1618532118-0.090331020.909669
ENST00000587718ENST00000543392CAPNS1chr1936631950+NOMO2chr1618532118-0.201204240.79879576
ENST00000590874ENST00000330537CAPNS1chr1936631950+NOMO2chr1618532118-0.72008990.27991012
ENST00000590874ENST00000381474CAPNS1chr1936631950+NOMO2chr1618532118-0.203192010.796808
ENST00000590874ENST00000543392CAPNS1chr1936631950+NOMO2chr1618532118-0.083501990.916498
ENST00000588815ENST00000330537CAPNS1chr1936631950+NOMO2chr1618532118-0.73167890.26832107
ENST00000588815ENST00000381474CAPNS1chr1936631950+NOMO2chr1618532118-0.217149240.7828508
ENST00000588815ENST00000543392CAPNS1chr1936631950+NOMO2chr1618532118-0.049926710.95007324
ENST00000588780ENST00000330537CAPNS1chr1936631950+NOMO2chr1618532118-0.767453130.2325469
ENST00000588780ENST00000381474CAPNS1chr1936631950+NOMO2chr1618532118-0.076018260.9239818
ENST00000588780ENST00000543392CAPNS1chr1936631950+NOMO2chr1618532118-0.062476110.93752384

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Fusion Genomic Features for CAPNS1-NOMO2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for CAPNS1-NOMO2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr19:36631950/chr16:18532118)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.NOMO2

Q5JPE7

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning, via its interaction with NCLN. {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneNOMO2chr19:36631950chr16:18532118ENST000003305370311177_126701223.0Topological domainCytoplasmic
TgeneNOMO2chr19:36631950chr16:18532118ENST0000033053703132_115501223.0Topological domainLumenal
TgeneNOMO2chr19:36631950chr16:18532118ENST000003814740321177_126701268.0Topological domainCytoplasmic
TgeneNOMO2chr19:36631950chr16:18532118ENST0000038147403232_115501268.0Topological domainLumenal
TgeneNOMO2chr19:36631950chr16:18532118ENST000003305370311156_117601223.0TransmembraneHelical
TgeneNOMO2chr19:36631950chr16:18532118ENST000003814740321156_117601268.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCAPNS1chr19:36631950chr16:18532118ENST00000246533+111108_1190269.0Calcium binding1
HgeneCAPNS1chr19:36631950chr16:18532118ENST00000246533+111152_1630269.0Calcium binding2
HgeneCAPNS1chr19:36631950chr16:18532118ENST00000246533+111182_1930269.0Calcium binding3
HgeneCAPNS1chr19:36631950chr16:18532118ENST00000587718+110108_1190323.0Calcium binding1
HgeneCAPNS1chr19:36631950chr16:18532118ENST00000587718+110152_1630323.0Calcium binding2
HgeneCAPNS1chr19:36631950chr16:18532118ENST00000587718+110182_1930323.0Calcium binding3
HgeneCAPNS1chr19:36631950chr16:18532118ENST00000588815+111108_1190269.0Calcium binding1
HgeneCAPNS1chr19:36631950chr16:18532118ENST00000588815+111152_1630269.0Calcium binding2
HgeneCAPNS1chr19:36631950chr16:18532118ENST00000588815+111182_1930269.0Calcium binding3
HgeneCAPNS1chr19:36631950chr16:18532118ENST00000246533+11110_260269.0Compositional biasNote=Poly-Gly
HgeneCAPNS1chr19:36631950chr16:18532118ENST00000246533+1111_660269.0Compositional biasNote=Gly-rich (hydrophobic)
HgeneCAPNS1chr19:36631950chr16:18532118ENST00000246533+11135_560269.0Compositional biasNote=Poly-Gly
HgeneCAPNS1chr19:36631950chr16:18532118ENST00000246533+11178_830269.0Compositional biasNote=Poly-Pro
HgeneCAPNS1chr19:36631950chr16:18532118ENST00000587718+11010_260323.0Compositional biasNote=Poly-Gly
HgeneCAPNS1chr19:36631950chr16:18532118ENST00000587718+1101_660323.0Compositional biasNote=Gly-rich (hydrophobic)
HgeneCAPNS1chr19:36631950chr16:18532118ENST00000587718+11035_560323.0Compositional biasNote=Poly-Gly
HgeneCAPNS1chr19:36631950chr16:18532118ENST00000587718+11078_830323.0Compositional biasNote=Poly-Pro
HgeneCAPNS1chr19:36631950chr16:18532118ENST00000588815+11110_260269.0Compositional biasNote=Poly-Gly
HgeneCAPNS1chr19:36631950chr16:18532118ENST00000588815+1111_660269.0Compositional biasNote=Gly-rich (hydrophobic)
HgeneCAPNS1chr19:36631950chr16:18532118ENST00000588815+11135_560269.0Compositional biasNote=Poly-Gly
HgeneCAPNS1chr19:36631950chr16:18532118ENST00000588815+11178_830269.0Compositional biasNote=Poly-Pro
HgeneCAPNS1chr19:36631950chr16:18532118ENST00000246533+111139_1720269.0DomainEF-hand 2
HgeneCAPNS1chr19:36631950chr16:18532118ENST00000246533+111169_2040269.0DomainEF-hand 3
HgeneCAPNS1chr19:36631950chr16:18532118ENST00000246533+111205_2330269.0DomainEF-hand 4
HgeneCAPNS1chr19:36631950chr16:18532118ENST00000246533+111234_2680269.0DomainEF-hand 5
HgeneCAPNS1chr19:36631950chr16:18532118ENST00000246533+11191_1250269.0DomainEF-hand 1%3B atypical
HgeneCAPNS1chr19:36631950chr16:18532118ENST00000587718+110139_1720323.0DomainEF-hand 2
HgeneCAPNS1chr19:36631950chr16:18532118ENST00000587718+110169_2040323.0DomainEF-hand 3
HgeneCAPNS1chr19:36631950chr16:18532118ENST00000587718+110205_2330323.0DomainEF-hand 4
HgeneCAPNS1chr19:36631950chr16:18532118ENST00000587718+110234_2680323.0DomainEF-hand 5
HgeneCAPNS1chr19:36631950chr16:18532118ENST00000587718+11091_1250323.0DomainEF-hand 1%3B atypical
HgeneCAPNS1chr19:36631950chr16:18532118ENST00000588815+111139_1720269.0DomainEF-hand 2
HgeneCAPNS1chr19:36631950chr16:18532118ENST00000588815+111169_2040269.0DomainEF-hand 3
HgeneCAPNS1chr19:36631950chr16:18532118ENST00000588815+111205_2330269.0DomainEF-hand 4
HgeneCAPNS1chr19:36631950chr16:18532118ENST00000588815+111234_2680269.0DomainEF-hand 5
HgeneCAPNS1chr19:36631950chr16:18532118ENST00000588815+11191_1250269.0DomainEF-hand 1%3B atypical


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Fusion Gene Sequence for CAPNS1-NOMO2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>12924_12924_1_CAPNS1-NOMO2_CAPNS1_chr19_36631950_ENST00000246533_NOMO2_chr16_18532118_ENST00000330537_length(transcript)=2695nt_BP=755nt
TGCCATCCGGGCTGCTGCAGGCACTGGGAAAGGCAATCCAGCCTCAATCCTCGCCACAGACACGGGCGACTGTCCCCCAGCGTGTGAGTC
AAACCATACTCCAGGCCTCCAGGAGGTGTTTGTCGCGACAACACCTGCAGAGGGCCCGTGCGGAGTCCCTTAGTGAGCGGACCGAAAACC
GCCACCCTGGAAGGATATTGGCATGCCCTAGGGTGAAAATTCACACTACGACACTCGGGGGGTGGGTCCCCTCCGAGTTCTCGTCCGCGG
GTGCCTCCACCCAGACCTGAGGGGTGTCGGGAAGACCCCCGCCTACCGAGTCAGGGCGGGATTAAGACCTCCGGCGCTGGAAACGCGTAG
GGCGGGGCCCAGACCTGGATCCAGCTAGCCGGGCGGTGTGGGGTGCGCATGCGCAATGTCCGCTTCGGCTCTAGGACCGCGCGGGCGACA
GCAGGGCCGCGGTGCAGTGTCCGACCCGAGAGTTGCGGCCTGAGTCACCGGCCCCGCCCTCCGGAGCCGGACGCTGCGGGAGGCCCGGGA
GCGGCAGTGGAACCGACTCCCAGAACTCCGGACGTGTGCGGCGGCGGCGGCGGGGGAGGCGGGGGCCTGGGTGGGGGCCTGGGAAATGTG
CTTGGAGGCCTGATCAGCGGGGCCGGGGGCGGCGGCGGCGGCGGCGGCGGCGGCGGCGGTGGTGGAGGCGGCGGTGGCGGTGGAACGGCC
ATGCGCATCCTAGGCGGAGTCATCAGCGCCATCAGCTCATTCCTTTGCTGCTGCAGTTGACAAGCCGGCTACAGGGAGTCGGCGCGCTCG
GCCAGGCAGCCTCTGACAATAGCGGCCCAGAAGATGCAAAGAGACAAGCCAAGAAACAGAAGACAAGGCGGACGTGAGGAGGAAGGGGAC
AGTTGCAGTCTCACTTGGGACAGGCCACAGCCAGGGGTCCGGCCACTACCCGCCCGTGGGATAAAAGCCAAAAGCATGCGTCAGCTAACT
TCAGCCTGTGCTGCTGGGCCCGCACCCCATGTCCCTTGTCACTGTGGCATCCTGCACCCATCCTCACCCCTCCGTAGAGCCCCTCGTGCA
ATGCAATGAATGGACCCTCCTGTCACTCTGCTGAACAGAATTTATTTTCTGAGTCAAATATAATTTATTATTATTTTTGTCAAAGAAGTA
TTTAAGCTGTGCTGTGGTGTGAGAATGTCATTCTTGATCTTCAGCCTTCGTTTGCAAGAAGAGTTCCAGTTGATGTGGTGTTTGGTTCCA
TGGCGGGGTACCCTAGGGATTCATCTGTTTTCTTCACTTCCCTTTGCATCTGAGATCCTGCTGGAAACCACGGCAACCTGTATCCACTAT
TAGGAGGTAAAAATCAATAAAATGGCCCATTCATTTGTGTTGTAGCTCAAGGAAGCTGCCTGAACAGGACATCGCACAAGGATCCTACAT
TGCCCTGCCATTGACGCTGCTGGTTCTGCTGGCCGGTTACAACCATGACAAGAACTATGTTGTGCTTCTGGACTCCACACTCCCCAGATC
CCAGTATGACTACATCTTGCCTCAAGTTTCTTTCACCGCAGTGGGCTACCATAAACACATCACCTTGATTTTTAATCCCACGGTCAAGCT
TTACAAAAGCGAAAACCTCGACAATCCAATCCAGACAGTTTCCCTTGGCCAGTCCCTGTTCTTCCATTTCCCCCCACTGCTCAGAGATGG
CGAGGTTGGGAATAATGACATCGATGATGTAAACATCATAGTTTTCCGGCAGATTAATCAATTTGATTTAAGTGGAAATGTGATCACTTC
CTCTGAATACCTTCCTACGTTATGGCCGGGATGTGTGTACCACGTTCAGCTCAAGGCAGAAGGCAACGACCACATTGAGCGGGCGCTCCC
CCACCATAGGGTGATTGAGTTGCTATGGCACAGTGTCTTCCTTAAACGGAGAGCCCGAACAAGGGGTTGCCATGGAAGCGGTGGGCCAGA
ACGACTGCAGCATTTACGGAGAAGACACCGTGACAGACGAAGAGGGCAAGTTCAGATTACGTGGATTGCTGAGCCCTGGCCAGTATTACT
TCAAACCCATGATGAAGGAGTTCCGGTTTGAGCCATCCTCACAGATGATCGAGGTGCAGGAAGGCCAGAACCTGAAGATCACCATCACGG
GGTACCGAACCGCTTACAGATAAAAGCTGAGGATGACCAGCCCCTCCCGGGAGTCCTCTTATCCCTGAGTGGTGGCCTGTTTCGTTCCAA
CCTCTTGACCCAGGACAACGGCATTCTGACATTCTCAAACCTGTGTTGGCCCCCTGCACAGTGACCTGGAGTACACGGTGACCTCACAGA
AGGAGGGCTATGTTCTGACTGCAGTGGAAGGAACCATCGGAGACTTCAAGGCCTATGCCCTGGCAGGCGTAAGCTTTGAGAAAGCTGCCC
AGGGAAGCTGATCGAGATCCACGGGAAGGCAGGCCTGTTTTTAGAAGGCCAGATCCACCCCGAGTTGGAAGGAGTCGAGATTGTCATCAG
TGAAAAGGGGGCAAGTTCACCGCTGATCACAGTCTTTACTGATGACAAAGGTGCCTACAGGTCTGGAGAGAAAATCACTGTTACACCGTC

>12924_12924_1_CAPNS1-NOMO2_CAPNS1_chr19_36631950_ENST00000246533_NOMO2_chr16_18532118_ENST00000330537_length(amino acids)=238AA_BP=
MCCSSRKLPEQDIAQGSYIALPLTLLVLLAGYNHDKNYVVLLDSTLPRSQYDYILPQVSFTAVGYHKHITLIFNPTVKLYKSENLDNPIQ
TVSLGQSLFFHFPPLLRDGEVGNNDIDDVNIIVFRQINQFDLSGNVITSSEYLPTLWPGCVYHVQLKAEGNDHIERALPHHRVIELLWHS

--------------------------------------------------------------
>12924_12924_2_CAPNS1-NOMO2_CAPNS1_chr19_36631950_ENST00000246533_NOMO2_chr16_18532118_ENST00000381474_length(transcript)=2359nt_BP=755nt
TGCCATCCGGGCTGCTGCAGGCACTGGGAAAGGCAATCCAGCCTCAATCCTCGCCACAGACACGGGCGACTGTCCCCCAGCGTGTGAGTC
AAACCATACTCCAGGCCTCCAGGAGGTGTTTGTCGCGACAACACCTGCAGAGGGCCCGTGCGGAGTCCCTTAGTGAGCGGACCGAAAACC
GCCACCCTGGAAGGATATTGGCATGCCCTAGGGTGAAAATTCACACTACGACACTCGGGGGGTGGGTCCCCTCCGAGTTCTCGTCCGCGG
GTGCCTCCACCCAGACCTGAGGGGTGTCGGGAAGACCCCCGCCTACCGAGTCAGGGCGGGATTAAGACCTCCGGCGCTGGAAACGCGTAG
GGCGGGGCCCAGACCTGGATCCAGCTAGCCGGGCGGTGTGGGGTGCGCATGCGCAATGTCCGCTTCGGCTCTAGGACCGCGCGGGCGACA
GCAGGGCCGCGGTGCAGTGTCCGACCCGAGAGTTGCGGCCTGAGTCACCGGCCCCGCCCTCCGGAGCCGGACGCTGCGGGAGGCCCGGGA
GCGGCAGTGGAACCGACTCCCAGAACTCCGGACGTGTGCGGCGGCGGCGGCGGGGGAGGCGGGGGCCTGGGTGGGGGCCTGGGAAATGTG
CTTGGAGGCCTGATCAGCGGGGCCGGGGGCGGCGGCGGCGGCGGCGGCGGCGGCGGCGGTGGTGGAGGCGGCGGTGGCGGTGGAACGGCC
ATGCGCATCCTAGGCGGAGTCATCAGCGCCATCAGCCTTCGTTTGCAAGAAGAGTTCCAGTTGATGTGGTGTTTGGTTCCATGGCGGGGT
ACCCTAGGGATTCATCTGTTTTCTTCACTTCCCTTTGCATCTGAGATCCTGCTGGAAACCACGGCAACCTGTATCCACTATTAGGAGGTA
AAAATCAATAAAATGGCCCATTCATTTGTGTTGTACTCATTCCTTTGCTGCTGCAGTTGACAAGCCGGCTACAGGGAGTCGGCGCGCTCG
GCCAGGCAGCCTCTGACAATAGCGGCCCAGAAGATGCAAAGAGACAAGCCAAGAAACAGAAGACAAGGCGGACAGGAAGCTGCCTGAACA
GGACATCGCACAAGGATCCTACATTGCCCTGCCATTGACGCTGCTGGTTCTGCTGGCCGGTTACAACCATGACAAGAACTATGTTGTGCT
TCTGGACTCCACACTCCCCAGATCCCAGTATGACTACATCTTGCCTCAAGTTTCTTTCACCGCAGTGGGCTACCATAAACACATCACCTT
GATTTTTAATCCCACGGTCAAGCTTTACAAAAGCGAAAACCTCGACAATCCAATCCAGACAGTTTCCCTTGGCCAGTCCCTGTTCTTCCA
TTTCCCCCCACTGCTCAGAGATGGCGAGGTTGGGAATAATGACATCGATGATGTAAACATCATAGTTTTCCGGCAGATTAATCAATTTGA
TTTAAGTGGAAATGTGATCACTTCCTCTGAATACCTTCCTACGTTATGGCCGGGATGTGTGTACCACGTTCAGCTCAAGGCAGAAGGCAA
CGACCACATTGAGCGGGCGCTCCCCCACCATAGGGTGATTGAGTTGCTATGGCACAGTGTCTTCCTTAAACGGAGAGCCCGAACAAGGGG
TTGCCATGGAAGCGGTGGGCCAGAACGACTGCAGCATTTACGGAGAAGACACCGTGACAGACGAAGAGGGCAAGTTCAGATTACGTGGAT
TGCTGAGCCCTGGCCAGTATTACTTCAAACCCATGATGAAGGAGTTCCGGTTTGAGCCATCCTCACAGATGATCGAGGTGCAGGAAGGCC
AGAACCTGAAGATCACCATCACGGGGTACCGAACCGCTTACAGATAAAAGCTGAGGATGACCAGCCCCTCCCGGGAGTCCTCTTATCCCT
GAGTGGTGGCCTGTTTCGTTCCAACCTCTTGACCCAGGACAACGGCATTCTGACATTCTCAAACCTGTGTTGGCCCCCTGCACAGTGACC
TGGAGTACACGGTGACCTCACAGAAGGAGGGCTATGTTCTGACTGCAGTGGAAGGAACCATCGGAGACTTCAAGGCCTATGCCCTGGCAG
GCGTAAGCTTTGAGAAAGCTGCCCAGGGAAGCTGATCGAGATCCACGGGAAGGCAGGCCTGTTTTTAGAAGGCCAGATCCACCCCGAGTT
GGAAGGAGTCGAGATTGTCATCAGTGAAAAGGGGGCAAGTTCACCGCTGATCACAGTCTTTACTGATGACAAAGGTGCCTACAGGTCTGG
AGAGAAAATCACTGTTACACCGTCATCTAAAGAGCTGCTCTTTTATCCCCCTTCAATGGAAGCCGTTGTCAGTGGAGCCCTTCTCGTATG

>12924_12924_2_CAPNS1-NOMO2_CAPNS1_chr19_36631950_ENST00000246533_NOMO2_chr16_18532118_ENST00000381474_length(amino acids)=231AA_BP=
MPEQDIAQGSYIALPLTLLVLLAGYNHDKNYVVLLDSTLPRSQYDYILPQVSFTAVGYHKHITLIFNPTVKLYKSENLDNPIQTVSLGQS
LFFHFPPLLRDGEVGNNDIDDVNIIVFRQINQFDLSGNVITSSEYLPTLWPGCVYHVQLKAEGNDHIERALPHHRVIELLWHSVFLKRRA

--------------------------------------------------------------
>12924_12924_3_CAPNS1-NOMO2_CAPNS1_chr19_36631950_ENST00000246533_NOMO2_chr16_18532118_ENST00000543392_length(transcript)=2352nt_BP=755nt
TGCCATCCGGGCTGCTGCAGGCACTGGGAAAGGCAATCCAGCCTCAATCCTCGCCACAGACACGGGCGACTGTCCCCCAGCGTGTGAGTC
AAACCATACTCCAGGCCTCCAGGAGGTGTTTGTCGCGACAACACCTGCAGAGGGCCCGTGCGGAGTCCCTTAGTGAGCGGACCGAAAACC
GCCACCCTGGAAGGATATTGGCATGCCCTAGGGTGAAAATTCACACTACGACACTCGGGGGGTGGGTCCCCTCCGAGTTCTCGTCCGCGG
GTGCCTCCACCCAGACCTGAGGGGTGTCGGGAAGACCCCCGCCTACCGAGTCAGGGCGGGATTAAGACCTCCGGCGCTGGAAACGCGTAG
GGCGGGGCCCAGACCTGGATCCAGCTAGCCGGGCGGTGTGGGGTGCGCATGCGCAATGTCCGCTTCGGCTCTAGGACCGCGCGGGCGACA
GCAGGGCCGCGGTGCAGTGTCCGACCCGAGAGTTGCGGCCTGAGTCACCGGCCCCGCCCTCCGGAGCCGGACGCTGCGGGAGGCCCGGGA
GCGGCAGTGGAACCGACTCCCAGAACTCCGGACGTGTGCGGCGGCGGCGGCGGGGGAGGCGGGGGCCTGGGTGGGGGCCTGGGAAATGTG
CTTGGAGGCCTGATCAGCGGGGCCGGGGGCGGCGGCGGCGGCGGCGGCGGCGGCGGCGGTGGTGGAGGCGGCGGTGGCGGTGGAACGGCC
ATGCGCATCCTAGGCGGAGTCATCAGCGCCATCAGCCTTCGTTTGCAAGAAGAGTTCCAGTTGATGTGGTGTTTGGTTCCATGGCGGGGT
ACCCTAGGGATTCATCTGTTTTCTTCACTTCCCTTTGCATCTGAGATCCTGCTGGAAACCACGGCAACCTGTATCCACTATTAGGAGGTA
AAAATCAATAAAATGGCCCATTCATTTGCTCATTCCTTTGCTGCTGCAGTTGACAAGCCGGCTACAGGGAGTCGGCGCGCTCGGCCAGGC
AGCCTCTGACAATAGCGGCCCAGAAGATGCAAAGAGACAAGCCAAGAAACAGAAGACAAGGCGGACAGGAAGCTGCCTGAACAGGACATC
GCACAAGGATCCTACATTGCCCTGCCATTGACGCTGCTGGTTCTGCTGGCCGGTTACAACCATGACAAGAACTATGTTGTGCTTCTGGAC
TCCACACTCCCCAGATCCCAGTATGACTACATCTTGCCTCAAGTTTCTTTCACCGCAGTGGGCTACCATAAACACATCACCTTGATTTTT
AATCCCACGGTCAAGCTTTACAAAAGCGAAAACCTCGACAATCCAATCCAGACAGTTTCCCTTGGCCAGTCCCTGTTCTTCCATTTCCCC
CCACTGCTCAGAGATGGCGAGGTTGGGAATAATGACATCGATGATGTAAACATCATAGTTTTCCGGCAGATTAATCAATTTGATTTAAGT
GGAAATGTGATCACTTCCTCTGAATACCTTCCTACGTTATGGCCGGGATGTGTGTACCACGTTCAGCTCAAGGCAGAAGGCAACGACCAC
ATTGAGCGGGCGCTCCCCCACCATAGGGTGATTGAGTTGCTATGGCACAGTGTCTTCCTTAAACGGAGAGCCCGAACAAGGGGTTGCCAT
GGAAGCGGTGGGCCAGAACGACTGCAGCATTTACGGAGAAGACACCGTGACAGACGAAGAGGGCAAGTTCAGATTACGTGGATTGCTGAG
CCCTGGCCAGTATTACTTCAAACCCATGATGAAGGAGTTCCGGTTTGAGCCATCCTCACAGATGATCGAGGTGCAGGAAGGCCAGAACCT
GAAGATCACCATCACGGGGTACCGAACCGCTTACAGATAAAAGCTGAGGATGACCAGCCCCTCCCGGGAGTCCTCTTATCCCTGAGTGGT
GGCCTGTTTCGTTCCAACCTCTTGACCCAGGACAACGGCATTCTGACATTCTCAAACCTGTGTTGGCCCCCTGCACAGTGACCTGGAGTA
CACGGTGACCTCACAGAAGGAGGGCTATGTTCTGACTGCAGTGGAAGGAACCATCGGAGACTTCAAGGCCTATGCCCTGGCAGGCGTAAG
CTTTGAGAAAGCTGCCCAGGGAAGCTGATCGAGATCCACGGGAAGGCAGGCCTGTTTTTAGAAGGCCAGATCCACCCCGAGTTGGAAGGA
GTCGAGATTGTCATCAGTGAAAAGGGGGCAAGTTCACCGCTGATCACAGTCTTTACTGATGACAAAGGTGCCTACAGGTCTGGAGAGAAA
ATCACTGTTACACCGTCATCTAAAGAGCTGCTCTTTTATCCCCCTTCAATGGAAGCCGTTGTCAGTGGAGCCCTTCTCGTATGATTTCTC

>12924_12924_3_CAPNS1-NOMO2_CAPNS1_chr19_36631950_ENST00000246533_NOMO2_chr16_18532118_ENST00000543392_length(amino acids)=231AA_BP=
MPEQDIAQGSYIALPLTLLVLLAGYNHDKNYVVLLDSTLPRSQYDYILPQVSFTAVGYHKHITLIFNPTVKLYKSENLDNPIQTVSLGQS
LFFHFPPLLRDGEVGNNDIDDVNIIVFRQINQFDLSGNVITSSEYLPTLWPGCVYHVQLKAEGNDHIERALPHHRVIELLWHSVFLKRRA

--------------------------------------------------------------
>12924_12924_4_CAPNS1-NOMO2_CAPNS1_chr19_36631950_ENST00000587718_NOMO2_chr16_18532118_ENST00000330537_length(transcript)=2162nt_BP=222nt
CCCGGGAGCGGCAGTGGAACCGACTCCCAGAACTCCGGACGTGTGCGGCGGCGGCGGCGGGGGAGGCGGGGGCCTGGGTGGGGGCCTGGG
AAATGTGCTTGGAGGCCTGATCAGCGGGGCCGGGGGCGGCGGCGGCGGCGGCGGCGGCGGCGGCGGTGGTGGAGGCGGCGGTGGCGGTGG
AACGGCCATGCGCATCCTAGGCGGAGTCATCAGCGCCATCAGCTCATTCCTTTGCTGCTGCAGTTGACAAGCCGGCTACAGGGAGTCGGC
GCGCTCGGCCAGGCAGCCTCTGACAATAGCGGCCCAGAAGATGCAAAGAGACAAGCCAAGAAACAGAAGACAAGGCGGACGTGAGGAGGA
AGGGGACAGTTGCAGTCTCACTTGGGACAGGCCACAGCCAGGGGTCCGGCCACTACCCGCCCGTGGGATAAAAGCCAAAAGCATGCGTCA
GCTAACTTCAGCCTGTGCTGCTGGGCCCGCACCCCATGTCCCTTGTCACTGTGGCATCCTGCACCCATCCTCACCCCTCCGTAGAGCCCC
TCGTGCAATGCAATGAATGGACCCTCCTGTCACTCTGCTGAACAGAATTTATTTTCTGAGTCAAATATAATTTATTATTATTTTTGTCAA
AGAAGTATTTAAGCTGTGCTGTGGTGTGAGAATGTCATTCTTGATCTTCAGCCTTCGTTTGCAAGAAGAGTTCCAGTTGATGTGGTGTTT
GGTTCCATGGCGGGGTACCCTAGGGATTCATCTGTTTTCTTCACTTCCCTTTGCATCTGAGATCCTGCTGGAAACCACGGCAACCTGTAT
CCACTATTAGGAGGTAAAAATCAATAAAATGGCCCATTCATTTGTGTTGTAGCTCAAGGAAGCTGCCTGAACAGGACATCGCACAAGGAT
CCTACATTGCCCTGCCATTGACGCTGCTGGTTCTGCTGGCCGGTTACAACCATGACAAGAACTATGTTGTGCTTCTGGACTCCACACTCC
CCAGATCCCAGTATGACTACATCTTGCCTCAAGTTTCTTTCACCGCAGTGGGCTACCATAAACACATCACCTTGATTTTTAATCCCACGG
TCAAGCTTTACAAAAGCGAAAACCTCGACAATCCAATCCAGACAGTTTCCCTTGGCCAGTCCCTGTTCTTCCATTTCCCCCCACTGCTCA
GAGATGGCGAGGTTGGGAATAATGACATCGATGATGTAAACATCATAGTTTTCCGGCAGATTAATCAATTTGATTTAAGTGGAAATGTGA
TCACTTCCTCTGAATACCTTCCTACGTTATGGCCGGGATGTGTGTACCACGTTCAGCTCAAGGCAGAAGGCAACGACCACATTGAGCGGG
CGCTCCCCCACCATAGGGTGATTGAGTTGCTATGGCACAGTGTCTTCCTTAAACGGAGAGCCCGAACAAGGGGTTGCCATGGAAGCGGTG
GGCCAGAACGACTGCAGCATTTACGGAGAAGACACCGTGACAGACGAAGAGGGCAAGTTCAGATTACGTGGATTGCTGAGCCCTGGCCAG
TATTACTTCAAACCCATGATGAAGGAGTTCCGGTTTGAGCCATCCTCACAGATGATCGAGGTGCAGGAAGGCCAGAACCTGAAGATCACC
ATCACGGGGTACCGAACCGCTTACAGATAAAAGCTGAGGATGACCAGCCCCTCCCGGGAGTCCTCTTATCCCTGAGTGGTGGCCTGTTTC
GTTCCAACCTCTTGACCCAGGACAACGGCATTCTGACATTCTCAAACCTGTGTTGGCCCCCTGCACAGTGACCTGGAGTACACGGTGACC
TCACAGAAGGAGGGCTATGTTCTGACTGCAGTGGAAGGAACCATCGGAGACTTCAAGGCCTATGCCCTGGCAGGCGTAAGCTTTGAGAAA
GCTGCCCAGGGAAGCTGATCGAGATCCACGGGAAGGCAGGCCTGTTTTTAGAAGGCCAGATCCACCCCGAGTTGGAAGGAGTCGAGATTG
TCATCAGTGAAAAGGGGGCAAGTTCACCGCTGATCACAGTCTTTACTGATGACAAAGGTGCCTACAGGTCTGGAGAGAAAATCACTGTTA
CACCGTCATCTAAAGAGCTGCTCTTTTATCCCCCTTCAATGGAAGCCGTTGTCAGTGGAGCCCTTCTCGTATGATTTCTCTTACTGGGCG

>12924_12924_4_CAPNS1-NOMO2_CAPNS1_chr19_36631950_ENST00000587718_NOMO2_chr16_18532118_ENST00000330537_length(amino acids)=238AA_BP=
MCCSSRKLPEQDIAQGSYIALPLTLLVLLAGYNHDKNYVVLLDSTLPRSQYDYILPQVSFTAVGYHKHITLIFNPTVKLYKSENLDNPIQ
TVSLGQSLFFHFPPLLRDGEVGNNDIDDVNIIVFRQINQFDLSGNVITSSEYLPTLWPGCVYHVQLKAEGNDHIERALPHHRVIELLWHS

--------------------------------------------------------------
>12924_12924_5_CAPNS1-NOMO2_CAPNS1_chr19_36631950_ENST00000587718_NOMO2_chr16_18532118_ENST00000381474_length(transcript)=1826nt_BP=222nt
CCCGGGAGCGGCAGTGGAACCGACTCCCAGAACTCCGGACGTGTGCGGCGGCGGCGGCGGGGGAGGCGGGGGCCTGGGTGGGGGCCTGGG
AAATGTGCTTGGAGGCCTGATCAGCGGGGCCGGGGGCGGCGGCGGCGGCGGCGGCGGCGGCGGCGGTGGTGGAGGCGGCGGTGGCGGTGG
AACGGCCATGCGCATCCTAGGCGGAGTCATCAGCGCCATCAGCCTTCGTTTGCAAGAAGAGTTCCAGTTGATGTGGTGTTTGGTTCCATG
GCGGGGTACCCTAGGGATTCATCTGTTTTCTTCACTTCCCTTTGCATCTGAGATCCTGCTGGAAACCACGGCAACCTGTATCCACTATTA
GGAGGTAAAAATCAATAAAATGGCCCATTCATTTGTGTTGTACTCATTCCTTTGCTGCTGCAGTTGACAAGCCGGCTACAGGGAGTCGGC
GCGCTCGGCCAGGCAGCCTCTGACAATAGCGGCCCAGAAGATGCAAAGAGACAAGCCAAGAAACAGAAGACAAGGCGGACAGGAAGCTGC
CTGAACAGGACATCGCACAAGGATCCTACATTGCCCTGCCATTGACGCTGCTGGTTCTGCTGGCCGGTTACAACCATGACAAGAACTATG
TTGTGCTTCTGGACTCCACACTCCCCAGATCCCAGTATGACTACATCTTGCCTCAAGTTTCTTTCACCGCAGTGGGCTACCATAAACACA
TCACCTTGATTTTTAATCCCACGGTCAAGCTTTACAAAAGCGAAAACCTCGACAATCCAATCCAGACAGTTTCCCTTGGCCAGTCCCTGT
TCTTCCATTTCCCCCCACTGCTCAGAGATGGCGAGGTTGGGAATAATGACATCGATGATGTAAACATCATAGTTTTCCGGCAGATTAATC
AATTTGATTTAAGTGGAAATGTGATCACTTCCTCTGAATACCTTCCTACGTTATGGCCGGGATGTGTGTACCACGTTCAGCTCAAGGCAG
AAGGCAACGACCACATTGAGCGGGCGCTCCCCCACCATAGGGTGATTGAGTTGCTATGGCACAGTGTCTTCCTTAAACGGAGAGCCCGAA
CAAGGGGTTGCCATGGAAGCGGTGGGCCAGAACGACTGCAGCATTTACGGAGAAGACACCGTGACAGACGAAGAGGGCAAGTTCAGATTA
CGTGGATTGCTGAGCCCTGGCCAGTATTACTTCAAACCCATGATGAAGGAGTTCCGGTTTGAGCCATCCTCACAGATGATCGAGGTGCAG
GAAGGCCAGAACCTGAAGATCACCATCACGGGGTACCGAACCGCTTACAGATAAAAGCTGAGGATGACCAGCCCCTCCCGGGAGTCCTCT
TATCCCTGAGTGGTGGCCTGTTTCGTTCCAACCTCTTGACCCAGGACAACGGCATTCTGACATTCTCAAACCTGTGTTGGCCCCCTGCAC
AGTGACCTGGAGTACACGGTGACCTCACAGAAGGAGGGCTATGTTCTGACTGCAGTGGAAGGAACCATCGGAGACTTCAAGGCCTATGCC
CTGGCAGGCGTAAGCTTTGAGAAAGCTGCCCAGGGAAGCTGATCGAGATCCACGGGAAGGCAGGCCTGTTTTTAGAAGGCCAGATCCACC
CCGAGTTGGAAGGAGTCGAGATTGTCATCAGTGAAAAGGGGGCAAGTTCACCGCTGATCACAGTCTTTACTGATGACAAAGGTGCCTACA
GGTCTGGAGAGAAAATCACTGTTACACCGTCATCTAAAGAGCTGCTCTTTTATCCCCCTTCAATGGAAGCCGTTGTCAGTGGAGCCCTTC

>12924_12924_5_CAPNS1-NOMO2_CAPNS1_chr19_36631950_ENST00000587718_NOMO2_chr16_18532118_ENST00000381474_length(amino acids)=231AA_BP=
MPEQDIAQGSYIALPLTLLVLLAGYNHDKNYVVLLDSTLPRSQYDYILPQVSFTAVGYHKHITLIFNPTVKLYKSENLDNPIQTVSLGQS
LFFHFPPLLRDGEVGNNDIDDVNIIVFRQINQFDLSGNVITSSEYLPTLWPGCVYHVQLKAEGNDHIERALPHHRVIELLWHSVFLKRRA

--------------------------------------------------------------
>12924_12924_6_CAPNS1-NOMO2_CAPNS1_chr19_36631950_ENST00000587718_NOMO2_chr16_18532118_ENST00000543392_length(transcript)=1819nt_BP=222nt
CCCGGGAGCGGCAGTGGAACCGACTCCCAGAACTCCGGACGTGTGCGGCGGCGGCGGCGGGGGAGGCGGGGGCCTGGGTGGGGGCCTGGG
AAATGTGCTTGGAGGCCTGATCAGCGGGGCCGGGGGCGGCGGCGGCGGCGGCGGCGGCGGCGGCGGTGGTGGAGGCGGCGGTGGCGGTGG
AACGGCCATGCGCATCCTAGGCGGAGTCATCAGCGCCATCAGCCTTCGTTTGCAAGAAGAGTTCCAGTTGATGTGGTGTTTGGTTCCATG
GCGGGGTACCCTAGGGATTCATCTGTTTTCTTCACTTCCCTTTGCATCTGAGATCCTGCTGGAAACCACGGCAACCTGTATCCACTATTA
GGAGGTAAAAATCAATAAAATGGCCCATTCATTTGCTCATTCCTTTGCTGCTGCAGTTGACAAGCCGGCTACAGGGAGTCGGCGCGCTCG
GCCAGGCAGCCTCTGACAATAGCGGCCCAGAAGATGCAAAGAGACAAGCCAAGAAACAGAAGACAAGGCGGACAGGAAGCTGCCTGAACA
GGACATCGCACAAGGATCCTACATTGCCCTGCCATTGACGCTGCTGGTTCTGCTGGCCGGTTACAACCATGACAAGAACTATGTTGTGCT
TCTGGACTCCACACTCCCCAGATCCCAGTATGACTACATCTTGCCTCAAGTTTCTTTCACCGCAGTGGGCTACCATAAACACATCACCTT
GATTTTTAATCCCACGGTCAAGCTTTACAAAAGCGAAAACCTCGACAATCCAATCCAGACAGTTTCCCTTGGCCAGTCCCTGTTCTTCCA
TTTCCCCCCACTGCTCAGAGATGGCGAGGTTGGGAATAATGACATCGATGATGTAAACATCATAGTTTTCCGGCAGATTAATCAATTTGA
TTTAAGTGGAAATGTGATCACTTCCTCTGAATACCTTCCTACGTTATGGCCGGGATGTGTGTACCACGTTCAGCTCAAGGCAGAAGGCAA
CGACCACATTGAGCGGGCGCTCCCCCACCATAGGGTGATTGAGTTGCTATGGCACAGTGTCTTCCTTAAACGGAGAGCCCGAACAAGGGG
TTGCCATGGAAGCGGTGGGCCAGAACGACTGCAGCATTTACGGAGAAGACACCGTGACAGACGAAGAGGGCAAGTTCAGATTACGTGGAT
TGCTGAGCCCTGGCCAGTATTACTTCAAACCCATGATGAAGGAGTTCCGGTTTGAGCCATCCTCACAGATGATCGAGGTGCAGGAAGGCC
AGAACCTGAAGATCACCATCACGGGGTACCGAACCGCTTACAGATAAAAGCTGAGGATGACCAGCCCCTCCCGGGAGTCCTCTTATCCCT
GAGTGGTGGCCTGTTTCGTTCCAACCTCTTGACCCAGGACAACGGCATTCTGACATTCTCAAACCTGTGTTGGCCCCCTGCACAGTGACC
TGGAGTACACGGTGACCTCACAGAAGGAGGGCTATGTTCTGACTGCAGTGGAAGGAACCATCGGAGACTTCAAGGCCTATGCCCTGGCAG
GCGTAAGCTTTGAGAAAGCTGCCCAGGGAAGCTGATCGAGATCCACGGGAAGGCAGGCCTGTTTTTAGAAGGCCAGATCCACCCCGAGTT
GGAAGGAGTCGAGATTGTCATCAGTGAAAAGGGGGCAAGTTCACCGCTGATCACAGTCTTTACTGATGACAAAGGTGCCTACAGGTCTGG
AGAGAAAATCACTGTTACACCGTCATCTAAAGAGCTGCTCTTTTATCCCCCTTCAATGGAAGCCGTTGTCAGTGGAGCCCTTCTCGTATG

>12924_12924_6_CAPNS1-NOMO2_CAPNS1_chr19_36631950_ENST00000587718_NOMO2_chr16_18532118_ENST00000543392_length(amino acids)=231AA_BP=
MPEQDIAQGSYIALPLTLLVLLAGYNHDKNYVVLLDSTLPRSQYDYILPQVSFTAVGYHKHITLIFNPTVKLYKSENLDNPIQTVSLGQS
LFFHFPPLLRDGEVGNNDIDDVNIIVFRQINQFDLSGNVITSSEYLPTLWPGCVYHVQLKAEGNDHIERALPHHRVIELLWHSVFLKRRA

--------------------------------------------------------------
>12924_12924_7_CAPNS1-NOMO2_CAPNS1_chr19_36631950_ENST00000588780_NOMO2_chr16_18532118_ENST00000330537_length(transcript)=2112nt_BP=172nt
GCGGCGGCGGGGGAGGCGGGGGCCTGGGTGGGGGCCTGGGAAATGTGCTTGGAGGCCTGATCAGCGGGGCCGGGGGCGGCGGCGGCGGCG
GCGGCGGCGGCGGCGGTGGTGGAGGCGGCGGTGGCGGTGGAACGGCCATGCGCATCCTAGGCGGAGTCATCAGCGCCATCAGCTCATTCC
TTTGCTGCTGCAGTTGACAAGCCGGCTACAGGGAGTCGGCGCGCTCGGCCAGGCAGCCTCTGACAATAGCGGCCCAGAAGATGCAAAGAG
ACAAGCCAAGAAACAGAAGACAAGGCGGACGTGAGGAGGAAGGGGACAGTTGCAGTCTCACTTGGGACAGGCCACAGCCAGGGGTCCGGC
CACTACCCGCCCGTGGGATAAAAGCCAAAAGCATGCGTCAGCTAACTTCAGCCTGTGCTGCTGGGCCCGCACCCCATGTCCCTTGTCACT
GTGGCATCCTGCACCCATCCTCACCCCTCCGTAGAGCCCCTCGTGCAATGCAATGAATGGACCCTCCTGTCACTCTGCTGAACAGAATTT
ATTTTCTGAGTCAAATATAATTTATTATTATTTTTGTCAAAGAAGTATTTAAGCTGTGCTGTGGTGTGAGAATGTCATTCTTGATCTTCA
GCCTTCGTTTGCAAGAAGAGTTCCAGTTGATGTGGTGTTTGGTTCCATGGCGGGGTACCCTAGGGATTCATCTGTTTTCTTCACTTCCCT
TTGCATCTGAGATCCTGCTGGAAACCACGGCAACCTGTATCCACTATTAGGAGGTAAAAATCAATAAAATGGCCCATTCATTTGTGTTGT
AGCTCAAGGAAGCTGCCTGAACAGGACATCGCACAAGGATCCTACATTGCCCTGCCATTGACGCTGCTGGTTCTGCTGGCCGGTTACAAC
CATGACAAGAACTATGTTGTGCTTCTGGACTCCACACTCCCCAGATCCCAGTATGACTACATCTTGCCTCAAGTTTCTTTCACCGCAGTG
GGCTACCATAAACACATCACCTTGATTTTTAATCCCACGGTCAAGCTTTACAAAAGCGAAAACCTCGACAATCCAATCCAGACAGTTTCC
CTTGGCCAGTCCCTGTTCTTCCATTTCCCCCCACTGCTCAGAGATGGCGAGGTTGGGAATAATGACATCGATGATGTAAACATCATAGTT
TTCCGGCAGATTAATCAATTTGATTTAAGTGGAAATGTGATCACTTCCTCTGAATACCTTCCTACGTTATGGCCGGGATGTGTGTACCAC
GTTCAGCTCAAGGCAGAAGGCAACGACCACATTGAGCGGGCGCTCCCCCACCATAGGGTGATTGAGTTGCTATGGCACAGTGTCTTCCTT
AAACGGAGAGCCCGAACAAGGGGTTGCCATGGAAGCGGTGGGCCAGAACGACTGCAGCATTTACGGAGAAGACACCGTGACAGACGAAGA
GGGCAAGTTCAGATTACGTGGATTGCTGAGCCCTGGCCAGTATTACTTCAAACCCATGATGAAGGAGTTCCGGTTTGAGCCATCCTCACA
GATGATCGAGGTGCAGGAAGGCCAGAACCTGAAGATCACCATCACGGGGTACCGAACCGCTTACAGATAAAAGCTGAGGATGACCAGCCC
CTCCCGGGAGTCCTCTTATCCCTGAGTGGTGGCCTGTTTCGTTCCAACCTCTTGACCCAGGACAACGGCATTCTGACATTCTCAAACCTG
TGTTGGCCCCCTGCACAGTGACCTGGAGTACACGGTGACCTCACAGAAGGAGGGCTATGTTCTGACTGCAGTGGAAGGAACCATCGGAGA
CTTCAAGGCCTATGCCCTGGCAGGCGTAAGCTTTGAGAAAGCTGCCCAGGGAAGCTGATCGAGATCCACGGGAAGGCAGGCCTGTTTTTA
GAAGGCCAGATCCACCCCGAGTTGGAAGGAGTCGAGATTGTCATCAGTGAAAAGGGGGCAAGTTCACCGCTGATCACAGTCTTTACTGAT
GACAAAGGTGCCTACAGGTCTGGAGAGAAAATCACTGTTACACCGTCATCTAAAGAGCTGCTCTTTTATCCCCCTTCAATGGAAGCCGTT

>12924_12924_7_CAPNS1-NOMO2_CAPNS1_chr19_36631950_ENST00000588780_NOMO2_chr16_18532118_ENST00000330537_length(amino acids)=238AA_BP=
MCCSSRKLPEQDIAQGSYIALPLTLLVLLAGYNHDKNYVVLLDSTLPRSQYDYILPQVSFTAVGYHKHITLIFNPTVKLYKSENLDNPIQ
TVSLGQSLFFHFPPLLRDGEVGNNDIDDVNIIVFRQINQFDLSGNVITSSEYLPTLWPGCVYHVQLKAEGNDHIERALPHHRVIELLWHS

--------------------------------------------------------------
>12924_12924_8_CAPNS1-NOMO2_CAPNS1_chr19_36631950_ENST00000588780_NOMO2_chr16_18532118_ENST00000381474_length(transcript)=1776nt_BP=172nt
GCGGCGGCGGGGGAGGCGGGGGCCTGGGTGGGGGCCTGGGAAATGTGCTTGGAGGCCTGATCAGCGGGGCCGGGGGCGGCGGCGGCGGCG
GCGGCGGCGGCGGCGGTGGTGGAGGCGGCGGTGGCGGTGGAACGGCCATGCGCATCCTAGGCGGAGTCATCAGCGCCATCAGCCTTCGTT
TGCAAGAAGAGTTCCAGTTGATGTGGTGTTTGGTTCCATGGCGGGGTACCCTAGGGATTCATCTGTTTTCTTCACTTCCCTTTGCATCTG
AGATCCTGCTGGAAACCACGGCAACCTGTATCCACTATTAGGAGGTAAAAATCAATAAAATGGCCCATTCATTTGTGTTGTACTCATTCC
TTTGCTGCTGCAGTTGACAAGCCGGCTACAGGGAGTCGGCGCGCTCGGCCAGGCAGCCTCTGACAATAGCGGCCCAGAAGATGCAAAGAG
ACAAGCCAAGAAACAGAAGACAAGGCGGACAGGAAGCTGCCTGAACAGGACATCGCACAAGGATCCTACATTGCCCTGCCATTGACGCTG
CTGGTTCTGCTGGCCGGTTACAACCATGACAAGAACTATGTTGTGCTTCTGGACTCCACACTCCCCAGATCCCAGTATGACTACATCTTG
CCTCAAGTTTCTTTCACCGCAGTGGGCTACCATAAACACATCACCTTGATTTTTAATCCCACGGTCAAGCTTTACAAAAGCGAAAACCTC
GACAATCCAATCCAGACAGTTTCCCTTGGCCAGTCCCTGTTCTTCCATTTCCCCCCACTGCTCAGAGATGGCGAGGTTGGGAATAATGAC
ATCGATGATGTAAACATCATAGTTTTCCGGCAGATTAATCAATTTGATTTAAGTGGAAATGTGATCACTTCCTCTGAATACCTTCCTACG
TTATGGCCGGGATGTGTGTACCACGTTCAGCTCAAGGCAGAAGGCAACGACCACATTGAGCGGGCGCTCCCCCACCATAGGGTGATTGAG
TTGCTATGGCACAGTGTCTTCCTTAAACGGAGAGCCCGAACAAGGGGTTGCCATGGAAGCGGTGGGCCAGAACGACTGCAGCATTTACGG
AGAAGACACCGTGACAGACGAAGAGGGCAAGTTCAGATTACGTGGATTGCTGAGCCCTGGCCAGTATTACTTCAAACCCATGATGAAGGA
GTTCCGGTTTGAGCCATCCTCACAGATGATCGAGGTGCAGGAAGGCCAGAACCTGAAGATCACCATCACGGGGTACCGAACCGCTTACAG
ATAAAAGCTGAGGATGACCAGCCCCTCCCGGGAGTCCTCTTATCCCTGAGTGGTGGCCTGTTTCGTTCCAACCTCTTGACCCAGGACAAC
GGCATTCTGACATTCTCAAACCTGTGTTGGCCCCCTGCACAGTGACCTGGAGTACACGGTGACCTCACAGAAGGAGGGCTATGTTCTGAC
TGCAGTGGAAGGAACCATCGGAGACTTCAAGGCCTATGCCCTGGCAGGCGTAAGCTTTGAGAAAGCTGCCCAGGGAAGCTGATCGAGATC
CACGGGAAGGCAGGCCTGTTTTTAGAAGGCCAGATCCACCCCGAGTTGGAAGGAGTCGAGATTGTCATCAGTGAAAAGGGGGCAAGTTCA
CCGCTGATCACAGTCTTTACTGATGACAAAGGTGCCTACAGGTCTGGAGAGAAAATCACTGTTACACCGTCATCTAAAGAGCTGCTCTTT

>12924_12924_8_CAPNS1-NOMO2_CAPNS1_chr19_36631950_ENST00000588780_NOMO2_chr16_18532118_ENST00000381474_length(amino acids)=231AA_BP=
MPEQDIAQGSYIALPLTLLVLLAGYNHDKNYVVLLDSTLPRSQYDYILPQVSFTAVGYHKHITLIFNPTVKLYKSENLDNPIQTVSLGQS
LFFHFPPLLRDGEVGNNDIDDVNIIVFRQINQFDLSGNVITSSEYLPTLWPGCVYHVQLKAEGNDHIERALPHHRVIELLWHSVFLKRRA

--------------------------------------------------------------
>12924_12924_9_CAPNS1-NOMO2_CAPNS1_chr19_36631950_ENST00000588780_NOMO2_chr16_18532118_ENST00000543392_length(transcript)=1769nt_BP=172nt
GCGGCGGCGGGGGAGGCGGGGGCCTGGGTGGGGGCCTGGGAAATGTGCTTGGAGGCCTGATCAGCGGGGCCGGGGGCGGCGGCGGCGGCG
GCGGCGGCGGCGGCGGTGGTGGAGGCGGCGGTGGCGGTGGAACGGCCATGCGCATCCTAGGCGGAGTCATCAGCGCCATCAGCCTTCGTT
TGCAAGAAGAGTTCCAGTTGATGTGGTGTTTGGTTCCATGGCGGGGTACCCTAGGGATTCATCTGTTTTCTTCACTTCCCTTTGCATCTG
AGATCCTGCTGGAAACCACGGCAACCTGTATCCACTATTAGGAGGTAAAAATCAATAAAATGGCCCATTCATTTGCTCATTCCTTTGCTG
CTGCAGTTGACAAGCCGGCTACAGGGAGTCGGCGCGCTCGGCCAGGCAGCCTCTGACAATAGCGGCCCAGAAGATGCAAAGAGACAAGCC
AAGAAACAGAAGACAAGGCGGACAGGAAGCTGCCTGAACAGGACATCGCACAAGGATCCTACATTGCCCTGCCATTGACGCTGCTGGTTC
TGCTGGCCGGTTACAACCATGACAAGAACTATGTTGTGCTTCTGGACTCCACACTCCCCAGATCCCAGTATGACTACATCTTGCCTCAAG
TTTCTTTCACCGCAGTGGGCTACCATAAACACATCACCTTGATTTTTAATCCCACGGTCAAGCTTTACAAAAGCGAAAACCTCGACAATC
CAATCCAGACAGTTTCCCTTGGCCAGTCCCTGTTCTTCCATTTCCCCCCACTGCTCAGAGATGGCGAGGTTGGGAATAATGACATCGATG
ATGTAAACATCATAGTTTTCCGGCAGATTAATCAATTTGATTTAAGTGGAAATGTGATCACTTCCTCTGAATACCTTCCTACGTTATGGC
CGGGATGTGTGTACCACGTTCAGCTCAAGGCAGAAGGCAACGACCACATTGAGCGGGCGCTCCCCCACCATAGGGTGATTGAGTTGCTAT
GGCACAGTGTCTTCCTTAAACGGAGAGCCCGAACAAGGGGTTGCCATGGAAGCGGTGGGCCAGAACGACTGCAGCATTTACGGAGAAGAC
ACCGTGACAGACGAAGAGGGCAAGTTCAGATTACGTGGATTGCTGAGCCCTGGCCAGTATTACTTCAAACCCATGATGAAGGAGTTCCGG
TTTGAGCCATCCTCACAGATGATCGAGGTGCAGGAAGGCCAGAACCTGAAGATCACCATCACGGGGTACCGAACCGCTTACAGATAAAAG
CTGAGGATGACCAGCCCCTCCCGGGAGTCCTCTTATCCCTGAGTGGTGGCCTGTTTCGTTCCAACCTCTTGACCCAGGACAACGGCATTC
TGACATTCTCAAACCTGTGTTGGCCCCCTGCACAGTGACCTGGAGTACACGGTGACCTCACAGAAGGAGGGCTATGTTCTGACTGCAGTG
GAAGGAACCATCGGAGACTTCAAGGCCTATGCCCTGGCAGGCGTAAGCTTTGAGAAAGCTGCCCAGGGAAGCTGATCGAGATCCACGGGA
AGGCAGGCCTGTTTTTAGAAGGCCAGATCCACCCCGAGTTGGAAGGAGTCGAGATTGTCATCAGTGAAAAGGGGGCAAGTTCACCGCTGA
TCACAGTCTTTACTGATGACAAAGGTGCCTACAGGTCTGGAGAGAAAATCACTGTTACACCGTCATCTAAAGAGCTGCTCTTTTATCCCC

>12924_12924_9_CAPNS1-NOMO2_CAPNS1_chr19_36631950_ENST00000588780_NOMO2_chr16_18532118_ENST00000543392_length(amino acids)=231AA_BP=
MPEQDIAQGSYIALPLTLLVLLAGYNHDKNYVVLLDSTLPRSQYDYILPQVSFTAVGYHKHITLIFNPTVKLYKSENLDNPIQTVSLGQS
LFFHFPPLLRDGEVGNNDIDDVNIIVFRQINQFDLSGNVITSSEYLPTLWPGCVYHVQLKAEGNDHIERALPHHRVIELLWHSVFLKRRA

--------------------------------------------------------------
>12924_12924_10_CAPNS1-NOMO2_CAPNS1_chr19_36631950_ENST00000588815_NOMO2_chr16_18532118_ENST00000330537_length(transcript)=2251nt_BP=311nt
CCGACTCCCAGAACTCCGGACGTGTGCGGCGGTAAGCGCCCGGCCCGTACCCCCTCCGCACCCCGCAACTCCGACTTTGGCGGCCCCCAG
ACCCGGCGAAACCGTGAAGTCTCGGCCTCAGGAGCCCCCCAGATCCATGGCGGCGGCGGGGGAGGCGGGGGCCTGGGTGGGGGCCTGGGA
AATGTGCTTGGAGGCCTGATCAGCGGGGCCGGGGGCGGCGGCGGCGGCGGCGGCGGCGGCGGCGGTGGTGGAGGCGGCGGTGGCGGTGGA
ACGGCCATGCGCATCCTAGGCGGAGTCATCAGCGCCATCAGCTCATTCCTTTGCTGCTGCAGTTGACAAGCCGGCTACAGGGAGTCGGCG
CGCTCGGCCAGGCAGCCTCTGACAATAGCGGCCCAGAAGATGCAAAGAGACAAGCCAAGAAACAGAAGACAAGGCGGACGTGAGGAGGAA
GGGGACAGTTGCAGTCTCACTTGGGACAGGCCACAGCCAGGGGTCCGGCCACTACCCGCCCGTGGGATAAAAGCCAAAAGCATGCGTCAG
CTAACTTCAGCCTGTGCTGCTGGGCCCGCACCCCATGTCCCTTGTCACTGTGGCATCCTGCACCCATCCTCACCCCTCCGTAGAGCCCCT
CGTGCAATGCAATGAATGGACCCTCCTGTCACTCTGCTGAACAGAATTTATTTTCTGAGTCAAATATAATTTATTATTATTTTTGTCAAA
GAAGTATTTAAGCTGTGCTGTGGTGTGAGAATGTCATTCTTGATCTTCAGCCTTCGTTTGCAAGAAGAGTTCCAGTTGATGTGGTGTTTG
GTTCCATGGCGGGGTACCCTAGGGATTCATCTGTTTTCTTCACTTCCCTTTGCATCTGAGATCCTGCTGGAAACCACGGCAACCTGTATC
CACTATTAGGAGGTAAAAATCAATAAAATGGCCCATTCATTTGTGTTGTAGCTCAAGGAAGCTGCCTGAACAGGACATCGCACAAGGATC
CTACATTGCCCTGCCATTGACGCTGCTGGTTCTGCTGGCCGGTTACAACCATGACAAGAACTATGTTGTGCTTCTGGACTCCACACTCCC
CAGATCCCAGTATGACTACATCTTGCCTCAAGTTTCTTTCACCGCAGTGGGCTACCATAAACACATCACCTTGATTTTTAATCCCACGGT
CAAGCTTTACAAAAGCGAAAACCTCGACAATCCAATCCAGACAGTTTCCCTTGGCCAGTCCCTGTTCTTCCATTTCCCCCCACTGCTCAG
AGATGGCGAGGTTGGGAATAATGACATCGATGATGTAAACATCATAGTTTTCCGGCAGATTAATCAATTTGATTTAAGTGGAAATGTGAT
CACTTCCTCTGAATACCTTCCTACGTTATGGCCGGGATGTGTGTACCACGTTCAGCTCAAGGCAGAAGGCAACGACCACATTGAGCGGGC
GCTCCCCCACCATAGGGTGATTGAGTTGCTATGGCACAGTGTCTTCCTTAAACGGAGAGCCCGAACAAGGGGTTGCCATGGAAGCGGTGG
GCCAGAACGACTGCAGCATTTACGGAGAAGACACCGTGACAGACGAAGAGGGCAAGTTCAGATTACGTGGATTGCTGAGCCCTGGCCAGT
ATTACTTCAAACCCATGATGAAGGAGTTCCGGTTTGAGCCATCCTCACAGATGATCGAGGTGCAGGAAGGCCAGAACCTGAAGATCACCA
TCACGGGGTACCGAACCGCTTACAGATAAAAGCTGAGGATGACCAGCCCCTCCCGGGAGTCCTCTTATCCCTGAGTGGTGGCCTGTTTCG
TTCCAACCTCTTGACCCAGGACAACGGCATTCTGACATTCTCAAACCTGTGTTGGCCCCCTGCACAGTGACCTGGAGTACACGGTGACCT
CACAGAAGGAGGGCTATGTTCTGACTGCAGTGGAAGGAACCATCGGAGACTTCAAGGCCTATGCCCTGGCAGGCGTAAGCTTTGAGAAAG
CTGCCCAGGGAAGCTGATCGAGATCCACGGGAAGGCAGGCCTGTTTTTAGAAGGCCAGATCCACCCCGAGTTGGAAGGAGTCGAGATTGT
CATCAGTGAAAAGGGGGCAAGTTCACCGCTGATCACAGTCTTTACTGATGACAAAGGTGCCTACAGGTCTGGAGAGAAAATCACTGTTAC
ACCGTCATCTAAAGAGCTGCTCTTTTATCCCCCTTCAATGGAAGCCGTTGTCAGTGGAGCCCTTCTCGTATGATTTCTCTTACTGGGCGC

>12924_12924_10_CAPNS1-NOMO2_CAPNS1_chr19_36631950_ENST00000588815_NOMO2_chr16_18532118_ENST00000330537_length(amino acids)=238AA_BP=
MCCSSRKLPEQDIAQGSYIALPLTLLVLLAGYNHDKNYVVLLDSTLPRSQYDYILPQVSFTAVGYHKHITLIFNPTVKLYKSENLDNPIQ
TVSLGQSLFFHFPPLLRDGEVGNNDIDDVNIIVFRQINQFDLSGNVITSSEYLPTLWPGCVYHVQLKAEGNDHIERALPHHRVIELLWHS

--------------------------------------------------------------
>12924_12924_11_CAPNS1-NOMO2_CAPNS1_chr19_36631950_ENST00000588815_NOMO2_chr16_18532118_ENST00000381474_length(transcript)=1915nt_BP=311nt
CCGACTCCCAGAACTCCGGACGTGTGCGGCGGTAAGCGCCCGGCCCGTACCCCCTCCGCACCCCGCAACTCCGACTTTGGCGGCCCCCAG
ACCCGGCGAAACCGTGAAGTCTCGGCCTCAGGAGCCCCCCAGATCCATGGCGGCGGCGGGGGAGGCGGGGGCCTGGGTGGGGGCCTGGGA
AATGTGCTTGGAGGCCTGATCAGCGGGGCCGGGGGCGGCGGCGGCGGCGGCGGCGGCGGCGGCGGTGGTGGAGGCGGCGGTGGCGGTGGA
ACGGCCATGCGCATCCTAGGCGGAGTCATCAGCGCCATCAGCCTTCGTTTGCAAGAAGAGTTCCAGTTGATGTGGTGTTTGGTTCCATGG
CGGGGTACCCTAGGGATTCATCTGTTTTCTTCACTTCCCTTTGCATCTGAGATCCTGCTGGAAACCACGGCAACCTGTATCCACTATTAG
GAGGTAAAAATCAATAAAATGGCCCATTCATTTGTGTTGTACTCATTCCTTTGCTGCTGCAGTTGACAAGCCGGCTACAGGGAGTCGGCG
CGCTCGGCCAGGCAGCCTCTGACAATAGCGGCCCAGAAGATGCAAAGAGACAAGCCAAGAAACAGAAGACAAGGCGGACAGGAAGCTGCC
TGAACAGGACATCGCACAAGGATCCTACATTGCCCTGCCATTGACGCTGCTGGTTCTGCTGGCCGGTTACAACCATGACAAGAACTATGT
TGTGCTTCTGGACTCCACACTCCCCAGATCCCAGTATGACTACATCTTGCCTCAAGTTTCTTTCACCGCAGTGGGCTACCATAAACACAT
CACCTTGATTTTTAATCCCACGGTCAAGCTTTACAAAAGCGAAAACCTCGACAATCCAATCCAGACAGTTTCCCTTGGCCAGTCCCTGTT
CTTCCATTTCCCCCCACTGCTCAGAGATGGCGAGGTTGGGAATAATGACATCGATGATGTAAACATCATAGTTTTCCGGCAGATTAATCA
ATTTGATTTAAGTGGAAATGTGATCACTTCCTCTGAATACCTTCCTACGTTATGGCCGGGATGTGTGTACCACGTTCAGCTCAAGGCAGA
AGGCAACGACCACATTGAGCGGGCGCTCCCCCACCATAGGGTGATTGAGTTGCTATGGCACAGTGTCTTCCTTAAACGGAGAGCCCGAAC
AAGGGGTTGCCATGGAAGCGGTGGGCCAGAACGACTGCAGCATTTACGGAGAAGACACCGTGACAGACGAAGAGGGCAAGTTCAGATTAC
GTGGATTGCTGAGCCCTGGCCAGTATTACTTCAAACCCATGATGAAGGAGTTCCGGTTTGAGCCATCCTCACAGATGATCGAGGTGCAGG
AAGGCCAGAACCTGAAGATCACCATCACGGGGTACCGAACCGCTTACAGATAAAAGCTGAGGATGACCAGCCCCTCCCGGGAGTCCTCTT
ATCCCTGAGTGGTGGCCTGTTTCGTTCCAACCTCTTGACCCAGGACAACGGCATTCTGACATTCTCAAACCTGTGTTGGCCCCCTGCACA
GTGACCTGGAGTACACGGTGACCTCACAGAAGGAGGGCTATGTTCTGACTGCAGTGGAAGGAACCATCGGAGACTTCAAGGCCTATGCCC
TGGCAGGCGTAAGCTTTGAGAAAGCTGCCCAGGGAAGCTGATCGAGATCCACGGGAAGGCAGGCCTGTTTTTAGAAGGCCAGATCCACCC
CGAGTTGGAAGGAGTCGAGATTGTCATCAGTGAAAAGGGGGCAAGTTCACCGCTGATCACAGTCTTTACTGATGACAAAGGTGCCTACAG
GTCTGGAGAGAAAATCACTGTTACACCGTCATCTAAAGAGCTGCTCTTTTATCCCCCTTCAATGGAAGCCGTTGTCAGTGGAGCCCTTCT

>12924_12924_11_CAPNS1-NOMO2_CAPNS1_chr19_36631950_ENST00000588815_NOMO2_chr16_18532118_ENST00000381474_length(amino acids)=231AA_BP=
MPEQDIAQGSYIALPLTLLVLLAGYNHDKNYVVLLDSTLPRSQYDYILPQVSFTAVGYHKHITLIFNPTVKLYKSENLDNPIQTVSLGQS
LFFHFPPLLRDGEVGNNDIDDVNIIVFRQINQFDLSGNVITSSEYLPTLWPGCVYHVQLKAEGNDHIERALPHHRVIELLWHSVFLKRRA

--------------------------------------------------------------
>12924_12924_12_CAPNS1-NOMO2_CAPNS1_chr19_36631950_ENST00000588815_NOMO2_chr16_18532118_ENST00000543392_length(transcript)=1908nt_BP=311nt
CCGACTCCCAGAACTCCGGACGTGTGCGGCGGTAAGCGCCCGGCCCGTACCCCCTCCGCACCCCGCAACTCCGACTTTGGCGGCCCCCAG
ACCCGGCGAAACCGTGAAGTCTCGGCCTCAGGAGCCCCCCAGATCCATGGCGGCGGCGGGGGAGGCGGGGGCCTGGGTGGGGGCCTGGGA
AATGTGCTTGGAGGCCTGATCAGCGGGGCCGGGGGCGGCGGCGGCGGCGGCGGCGGCGGCGGCGGTGGTGGAGGCGGCGGTGGCGGTGGA
ACGGCCATGCGCATCCTAGGCGGAGTCATCAGCGCCATCAGCCTTCGTTTGCAAGAAGAGTTCCAGTTGATGTGGTGTTTGGTTCCATGG
CGGGGTACCCTAGGGATTCATCTGTTTTCTTCACTTCCCTTTGCATCTGAGATCCTGCTGGAAACCACGGCAACCTGTATCCACTATTAG
GAGGTAAAAATCAATAAAATGGCCCATTCATTTGCTCATTCCTTTGCTGCTGCAGTTGACAAGCCGGCTACAGGGAGTCGGCGCGCTCGG
CCAGGCAGCCTCTGACAATAGCGGCCCAGAAGATGCAAAGAGACAAGCCAAGAAACAGAAGACAAGGCGGACAGGAAGCTGCCTGAACAG
GACATCGCACAAGGATCCTACATTGCCCTGCCATTGACGCTGCTGGTTCTGCTGGCCGGTTACAACCATGACAAGAACTATGTTGTGCTT
CTGGACTCCACACTCCCCAGATCCCAGTATGACTACATCTTGCCTCAAGTTTCTTTCACCGCAGTGGGCTACCATAAACACATCACCTTG
ATTTTTAATCCCACGGTCAAGCTTTACAAAAGCGAAAACCTCGACAATCCAATCCAGACAGTTTCCCTTGGCCAGTCCCTGTTCTTCCAT
TTCCCCCCACTGCTCAGAGATGGCGAGGTTGGGAATAATGACATCGATGATGTAAACATCATAGTTTTCCGGCAGATTAATCAATTTGAT
TTAAGTGGAAATGTGATCACTTCCTCTGAATACCTTCCTACGTTATGGCCGGGATGTGTGTACCACGTTCAGCTCAAGGCAGAAGGCAAC
GACCACATTGAGCGGGCGCTCCCCCACCATAGGGTGATTGAGTTGCTATGGCACAGTGTCTTCCTTAAACGGAGAGCCCGAACAAGGGGT
TGCCATGGAAGCGGTGGGCCAGAACGACTGCAGCATTTACGGAGAAGACACCGTGACAGACGAAGAGGGCAAGTTCAGATTACGTGGATT
GCTGAGCCCTGGCCAGTATTACTTCAAACCCATGATGAAGGAGTTCCGGTTTGAGCCATCCTCACAGATGATCGAGGTGCAGGAAGGCCA
GAACCTGAAGATCACCATCACGGGGTACCGAACCGCTTACAGATAAAAGCTGAGGATGACCAGCCCCTCCCGGGAGTCCTCTTATCCCTG
AGTGGTGGCCTGTTTCGTTCCAACCTCTTGACCCAGGACAACGGCATTCTGACATTCTCAAACCTGTGTTGGCCCCCTGCACAGTGACCT
GGAGTACACGGTGACCTCACAGAAGGAGGGCTATGTTCTGACTGCAGTGGAAGGAACCATCGGAGACTTCAAGGCCTATGCCCTGGCAGG
CGTAAGCTTTGAGAAAGCTGCCCAGGGAAGCTGATCGAGATCCACGGGAAGGCAGGCCTGTTTTTAGAAGGCCAGATCCACCCCGAGTTG
GAAGGAGTCGAGATTGTCATCAGTGAAAAGGGGGCAAGTTCACCGCTGATCACAGTCTTTACTGATGACAAAGGTGCCTACAGGTCTGGA
GAGAAAATCACTGTTACACCGTCATCTAAAGAGCTGCTCTTTTATCCCCCTTCAATGGAAGCCGTTGTCAGTGGAGCCCTTCTCGTATGA

>12924_12924_12_CAPNS1-NOMO2_CAPNS1_chr19_36631950_ENST00000588815_NOMO2_chr16_18532118_ENST00000543392_length(amino acids)=231AA_BP=
MPEQDIAQGSYIALPLTLLVLLAGYNHDKNYVVLLDSTLPRSQYDYILPQVSFTAVGYHKHITLIFNPTVKLYKSENLDNPIQTVSLGQS
LFFHFPPLLRDGEVGNNDIDDVNIIVFRQINQFDLSGNVITSSEYLPTLWPGCVYHVQLKAEGNDHIERALPHHRVIELLWHSVFLKRRA

--------------------------------------------------------------
>12924_12924_13_CAPNS1-NOMO2_CAPNS1_chr19_36631950_ENST00000590874_NOMO2_chr16_18532118_ENST00000330537_length(transcript)=2147nt_BP=207nt
GGAACCGACTCCCAGAACTCCGGACGTGTGCGGCGGCGGCGGCGGGGGAGGCGGGGGCCTGGGTGGGGGCCTGGGAAATGTGCTTGGAGG
CCTGATCAGCGGGGCCGGGGGCGGCGGCGGCGGCGGCGGCGGCGGCGGCGGTGGTGGAGGCGGCGGTGGCGGTGGAACGGCCATGCGCAT
CCTAGGCGGAGTCATCAGCGCCATCAGCTCATTCCTTTGCTGCTGCAGTTGACAAGCCGGCTACAGGGAGTCGGCGCGCTCGGCCAGGCA
GCCTCTGACAATAGCGGCCCAGAAGATGCAAAGAGACAAGCCAAGAAACAGAAGACAAGGCGGACGTGAGGAGGAAGGGGACAGTTGCAG
TCTCACTTGGGACAGGCCACAGCCAGGGGTCCGGCCACTACCCGCCCGTGGGATAAAAGCCAAAAGCATGCGTCAGCTAACTTCAGCCTG
TGCTGCTGGGCCCGCACCCCATGTCCCTTGTCACTGTGGCATCCTGCACCCATCCTCACCCCTCCGTAGAGCCCCTCGTGCAATGCAATG
AATGGACCCTCCTGTCACTCTGCTGAACAGAATTTATTTTCTGAGTCAAATATAATTTATTATTATTTTTGTCAAAGAAGTATTTAAGCT
GTGCTGTGGTGTGAGAATGTCATTCTTGATCTTCAGCCTTCGTTTGCAAGAAGAGTTCCAGTTGATGTGGTGTTTGGTTCCATGGCGGGG
TACCCTAGGGATTCATCTGTTTTCTTCACTTCCCTTTGCATCTGAGATCCTGCTGGAAACCACGGCAACCTGTATCCACTATTAGGAGGT
AAAAATCAATAAAATGGCCCATTCATTTGTGTTGTAGCTCAAGGAAGCTGCCTGAACAGGACATCGCACAAGGATCCTACATTGCCCTGC
CATTGACGCTGCTGGTTCTGCTGGCCGGTTACAACCATGACAAGAACTATGTTGTGCTTCTGGACTCCACACTCCCCAGATCCCAGTATG
ACTACATCTTGCCTCAAGTTTCTTTCACCGCAGTGGGCTACCATAAACACATCACCTTGATTTTTAATCCCACGGTCAAGCTTTACAAAA
GCGAAAACCTCGACAATCCAATCCAGACAGTTTCCCTTGGCCAGTCCCTGTTCTTCCATTTCCCCCCACTGCTCAGAGATGGCGAGGTTG
GGAATAATGACATCGATGATGTAAACATCATAGTTTTCCGGCAGATTAATCAATTTGATTTAAGTGGAAATGTGATCACTTCCTCTGAAT
ACCTTCCTACGTTATGGCCGGGATGTGTGTACCACGTTCAGCTCAAGGCAGAAGGCAACGACCACATTGAGCGGGCGCTCCCCCACCATA
GGGTGATTGAGTTGCTATGGCACAGTGTCTTCCTTAAACGGAGAGCCCGAACAAGGGGTTGCCATGGAAGCGGTGGGCCAGAACGACTGC
AGCATTTACGGAGAAGACACCGTGACAGACGAAGAGGGCAAGTTCAGATTACGTGGATTGCTGAGCCCTGGCCAGTATTACTTCAAACCC
ATGATGAAGGAGTTCCGGTTTGAGCCATCCTCACAGATGATCGAGGTGCAGGAAGGCCAGAACCTGAAGATCACCATCACGGGGTACCGA
ACCGCTTACAGATAAAAGCTGAGGATGACCAGCCCCTCCCGGGAGTCCTCTTATCCCTGAGTGGTGGCCTGTTTCGTTCCAACCTCTTGA
CCCAGGACAACGGCATTCTGACATTCTCAAACCTGTGTTGGCCCCCTGCACAGTGACCTGGAGTACACGGTGACCTCACAGAAGGAGGGC
TATGTTCTGACTGCAGTGGAAGGAACCATCGGAGACTTCAAGGCCTATGCCCTGGCAGGCGTAAGCTTTGAGAAAGCTGCCCAGGGAAGC
TGATCGAGATCCACGGGAAGGCAGGCCTGTTTTTAGAAGGCCAGATCCACCCCGAGTTGGAAGGAGTCGAGATTGTCATCAGTGAAAAGG
GGGCAAGTTCACCGCTGATCACAGTCTTTACTGATGACAAAGGTGCCTACAGGTCTGGAGAGAAAATCACTGTTACACCGTCATCTAAAG

>12924_12924_13_CAPNS1-NOMO2_CAPNS1_chr19_36631950_ENST00000590874_NOMO2_chr16_18532118_ENST00000330537_length(amino acids)=238AA_BP=
MCCSSRKLPEQDIAQGSYIALPLTLLVLLAGYNHDKNYVVLLDSTLPRSQYDYILPQVSFTAVGYHKHITLIFNPTVKLYKSENLDNPIQ
TVSLGQSLFFHFPPLLRDGEVGNNDIDDVNIIVFRQINQFDLSGNVITSSEYLPTLWPGCVYHVQLKAEGNDHIERALPHHRVIELLWHS

--------------------------------------------------------------
>12924_12924_14_CAPNS1-NOMO2_CAPNS1_chr19_36631950_ENST00000590874_NOMO2_chr16_18532118_ENST00000381474_length(transcript)=1811nt_BP=207nt
GGAACCGACTCCCAGAACTCCGGACGTGTGCGGCGGCGGCGGCGGGGGAGGCGGGGGCCTGGGTGGGGGCCTGGGAAATGTGCTTGGAGG
CCTGATCAGCGGGGCCGGGGGCGGCGGCGGCGGCGGCGGCGGCGGCGGCGGTGGTGGAGGCGGCGGTGGCGGTGGAACGGCCATGCGCAT
CCTAGGCGGAGTCATCAGCGCCATCAGCCTTCGTTTGCAAGAAGAGTTCCAGTTGATGTGGTGTTTGGTTCCATGGCGGGGTACCCTAGG
GATTCATCTGTTTTCTTCACTTCCCTTTGCATCTGAGATCCTGCTGGAAACCACGGCAACCTGTATCCACTATTAGGAGGTAAAAATCAA
TAAAATGGCCCATTCATTTGTGTTGTACTCATTCCTTTGCTGCTGCAGTTGACAAGCCGGCTACAGGGAGTCGGCGCGCTCGGCCAGGCA
GCCTCTGACAATAGCGGCCCAGAAGATGCAAAGAGACAAGCCAAGAAACAGAAGACAAGGCGGACAGGAAGCTGCCTGAACAGGACATCG
CACAAGGATCCTACATTGCCCTGCCATTGACGCTGCTGGTTCTGCTGGCCGGTTACAACCATGACAAGAACTATGTTGTGCTTCTGGACT
CCACACTCCCCAGATCCCAGTATGACTACATCTTGCCTCAAGTTTCTTTCACCGCAGTGGGCTACCATAAACACATCACCTTGATTTTTA
ATCCCACGGTCAAGCTTTACAAAAGCGAAAACCTCGACAATCCAATCCAGACAGTTTCCCTTGGCCAGTCCCTGTTCTTCCATTTCCCCC
CACTGCTCAGAGATGGCGAGGTTGGGAATAATGACATCGATGATGTAAACATCATAGTTTTCCGGCAGATTAATCAATTTGATTTAAGTG
GAAATGTGATCACTTCCTCTGAATACCTTCCTACGTTATGGCCGGGATGTGTGTACCACGTTCAGCTCAAGGCAGAAGGCAACGACCACA
TTGAGCGGGCGCTCCCCCACCATAGGGTGATTGAGTTGCTATGGCACAGTGTCTTCCTTAAACGGAGAGCCCGAACAAGGGGTTGCCATG
GAAGCGGTGGGCCAGAACGACTGCAGCATTTACGGAGAAGACACCGTGACAGACGAAGAGGGCAAGTTCAGATTACGTGGATTGCTGAGC
CCTGGCCAGTATTACTTCAAACCCATGATGAAGGAGTTCCGGTTTGAGCCATCCTCACAGATGATCGAGGTGCAGGAAGGCCAGAACCTG
AAGATCACCATCACGGGGTACCGAACCGCTTACAGATAAAAGCTGAGGATGACCAGCCCCTCCCGGGAGTCCTCTTATCCCTGAGTGGTG
GCCTGTTTCGTTCCAACCTCTTGACCCAGGACAACGGCATTCTGACATTCTCAAACCTGTGTTGGCCCCCTGCACAGTGACCTGGAGTAC
ACGGTGACCTCACAGAAGGAGGGCTATGTTCTGACTGCAGTGGAAGGAACCATCGGAGACTTCAAGGCCTATGCCCTGGCAGGCGTAAGC
TTTGAGAAAGCTGCCCAGGGAAGCTGATCGAGATCCACGGGAAGGCAGGCCTGTTTTTAGAAGGCCAGATCCACCCCGAGTTGGAAGGAG
TCGAGATTGTCATCAGTGAAAAGGGGGCAAGTTCACCGCTGATCACAGTCTTTACTGATGACAAAGGTGCCTACAGGTCTGGAGAGAAAA
TCACTGTTACACCGTCATCTAAAGAGCTGCTCTTTTATCCCCCTTCAATGGAAGCCGTTGTCAGTGGAGCCCTTCTCGTATGATTTCTCT

>12924_12924_14_CAPNS1-NOMO2_CAPNS1_chr19_36631950_ENST00000590874_NOMO2_chr16_18532118_ENST00000381474_length(amino acids)=231AA_BP=
MPEQDIAQGSYIALPLTLLVLLAGYNHDKNYVVLLDSTLPRSQYDYILPQVSFTAVGYHKHITLIFNPTVKLYKSENLDNPIQTVSLGQS
LFFHFPPLLRDGEVGNNDIDDVNIIVFRQINQFDLSGNVITSSEYLPTLWPGCVYHVQLKAEGNDHIERALPHHRVIELLWHSVFLKRRA

--------------------------------------------------------------
>12924_12924_15_CAPNS1-NOMO2_CAPNS1_chr19_36631950_ENST00000590874_NOMO2_chr16_18532118_ENST00000543392_length(transcript)=1804nt_BP=207nt
GGAACCGACTCCCAGAACTCCGGACGTGTGCGGCGGCGGCGGCGGGGGAGGCGGGGGCCTGGGTGGGGGCCTGGGAAATGTGCTTGGAGG
CCTGATCAGCGGGGCCGGGGGCGGCGGCGGCGGCGGCGGCGGCGGCGGCGGTGGTGGAGGCGGCGGTGGCGGTGGAACGGCCATGCGCAT
CCTAGGCGGAGTCATCAGCGCCATCAGCCTTCGTTTGCAAGAAGAGTTCCAGTTGATGTGGTGTTTGGTTCCATGGCGGGGTACCCTAGG
GATTCATCTGTTTTCTTCACTTCCCTTTGCATCTGAGATCCTGCTGGAAACCACGGCAACCTGTATCCACTATTAGGAGGTAAAAATCAA
TAAAATGGCCCATTCATTTGCTCATTCCTTTGCTGCTGCAGTTGACAAGCCGGCTACAGGGAGTCGGCGCGCTCGGCCAGGCAGCCTCTG
ACAATAGCGGCCCAGAAGATGCAAAGAGACAAGCCAAGAAACAGAAGACAAGGCGGACAGGAAGCTGCCTGAACAGGACATCGCACAAGG
ATCCTACATTGCCCTGCCATTGACGCTGCTGGTTCTGCTGGCCGGTTACAACCATGACAAGAACTATGTTGTGCTTCTGGACTCCACACT
CCCCAGATCCCAGTATGACTACATCTTGCCTCAAGTTTCTTTCACCGCAGTGGGCTACCATAAACACATCACCTTGATTTTTAATCCCAC
GGTCAAGCTTTACAAAAGCGAAAACCTCGACAATCCAATCCAGACAGTTTCCCTTGGCCAGTCCCTGTTCTTCCATTTCCCCCCACTGCT
CAGAGATGGCGAGGTTGGGAATAATGACATCGATGATGTAAACATCATAGTTTTCCGGCAGATTAATCAATTTGATTTAAGTGGAAATGT
GATCACTTCCTCTGAATACCTTCCTACGTTATGGCCGGGATGTGTGTACCACGTTCAGCTCAAGGCAGAAGGCAACGACCACATTGAGCG
GGCGCTCCCCCACCATAGGGTGATTGAGTTGCTATGGCACAGTGTCTTCCTTAAACGGAGAGCCCGAACAAGGGGTTGCCATGGAAGCGG
TGGGCCAGAACGACTGCAGCATTTACGGAGAAGACACCGTGACAGACGAAGAGGGCAAGTTCAGATTACGTGGATTGCTGAGCCCTGGCC
AGTATTACTTCAAACCCATGATGAAGGAGTTCCGGTTTGAGCCATCCTCACAGATGATCGAGGTGCAGGAAGGCCAGAACCTGAAGATCA
CCATCACGGGGTACCGAACCGCTTACAGATAAAAGCTGAGGATGACCAGCCCCTCCCGGGAGTCCTCTTATCCCTGAGTGGTGGCCTGTT
TCGTTCCAACCTCTTGACCCAGGACAACGGCATTCTGACATTCTCAAACCTGTGTTGGCCCCCTGCACAGTGACCTGGAGTACACGGTGA
CCTCACAGAAGGAGGGCTATGTTCTGACTGCAGTGGAAGGAACCATCGGAGACTTCAAGGCCTATGCCCTGGCAGGCGTAAGCTTTGAGA
AAGCTGCCCAGGGAAGCTGATCGAGATCCACGGGAAGGCAGGCCTGTTTTTAGAAGGCCAGATCCACCCCGAGTTGGAAGGAGTCGAGAT
TGTCATCAGTGAAAAGGGGGCAAGTTCACCGCTGATCACAGTCTTTACTGATGACAAAGGTGCCTACAGGTCTGGAGAGAAAATCACTGT
TACACCGTCATCTAAAGAGCTGCTCTTTTATCCCCCTTCAATGGAAGCCGTTGTCAGTGGAGCCCTTCTCGTATGATTTCTCTTACTGGG

>12924_12924_15_CAPNS1-NOMO2_CAPNS1_chr19_36631950_ENST00000590874_NOMO2_chr16_18532118_ENST00000543392_length(amino acids)=231AA_BP=
MPEQDIAQGSYIALPLTLLVLLAGYNHDKNYVVLLDSTLPRSQYDYILPQVSFTAVGYHKHITLIFNPTVKLYKSENLDNPIQTVSLGQS
LFFHFPPLLRDGEVGNNDIDDVNIIVFRQINQFDLSGNVITSSEYLPTLWPGCVYHVQLKAEGNDHIERALPHHRVIELLWHSVFLKRRA

--------------------------------------------------------------

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Fusion Gene PPI Analysis for CAPNS1-NOMO2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CAPNS1-NOMO2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CAPNS1-NOMO2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneCAPNS1C0033578Prostatic Neoplasms1CTD_human
HgeneCAPNS1C0376358Malignant neoplasm of prostate1CTD_human