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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:CAPZA2-MET (FusionGDB2 ID:HG830TG4233)

Fusion Gene Summary for CAPZA2-MET

check button Fusion gene summary
Fusion gene informationFusion gene name: CAPZA2-MET
Fusion gene ID: hg830tg4233
HgeneTgene
Gene symbol

CAPZA2

MET

Gene ID

830

4233

Gene namecapping actin protein of muscle Z-line subunit alpha 2MET proto-oncogene, receptor tyrosine kinase
SynonymsCAPPA2|CAPZAUTS9|DFNB97|HGFR|RCCP2|c-Met
Cytomap('CAPZA2')('MET')

7q31.2

7q31.2

Type of geneprotein-codingprotein-coding
DescriptionF-actin-capping protein subunit alpha-2F-actin capping protein alpha-2 subunitcapZ alpha-2capping actin protein of muscle Z-line alpha subunit 2capping protein (actin filament) muscle Z-line, alpha 2epididymis secretory sperm binding proteinhepatocyte growth factor receptorHGF receptorHGF/SF receptorSF receptorproto-oncogene c-Metscatter factor receptortyrosine-protein kinase Met
Modification date2020031320200315
UniProtAcc

P47755

P08581

Ensembl transtripts involved in fusion geneENST00000466023, ENST00000361183, 
ENST00000458284, ENST00000490693, 
ENST00000466023, ENST00000361183, 
ENST00000458284, ENST00000490693, 
Fusion gene scores* DoF score17 X 6 X 9=91814 X 18 X 10=2520
# samples 2027
** MAII scorelog2(20/918*10)=-2.19849415363908
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(27/2520*10)=-3.22239242133645
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CAPZA2 [Title/Abstract] AND MET [Title/Abstract] AND fusion [Title/Abstract]

Engineering and Functional Characterization of Fusion Genes Identifies Novel Oncogenic Drivers of Cancer (pmid: 28512244)
Most frequent breakpointCAPZA2(116550365)-MET(116409699), # samples:2
CAPZA2(116528244)-MET(116395409), # samples:2
CAPZA2(116528244)-MET(116414935), # samples:2
Anticipated loss of major functional domain due to fusion event.CAPZA2-MET seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
CAPZA2-MET seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
CAPZA2-MET seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
CAPZA2-MET seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
MET-CAPZA2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
MET-CAPZA2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
CAPZA2-MET seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
CAPZA2-MET seems lost the major protein functional domain in Tgene partner, which is a CGC due to the frame-shifted ORF.
CAPZA2-MET seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
CAPZA2-MET seems lost the major protein functional domain in Tgene partner, which is a kinase due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneMET

GO:0001886

endothelial cell morphogenesis

14500721

TgeneMET

GO:0035024

negative regulation of Rho protein signal transduction

25198505

TgeneMET

GO:0045944

positive regulation of transcription by RNA polymerase II

22521434

TgeneMET

GO:0050918

positive chemotaxis

15218527

TgeneMET

GO:0051497

negative regulation of stress fiber assembly

25198505

TgeneMET

GO:0070495

negative regulation of thrombin-activated receptor signaling pathway

25198505

TgeneMET

GO:0071526

semaphorin-plexin signaling pathway

15218527

TgeneMET

GO:1905098

negative regulation of guanyl-nucleotide exchange factor activity

25198505


check buttonFusion gene breakpoints across CAPZA2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across MET (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-AR-A1AN-01ACAPZA2chr7

116550365

-METchr7

116409699

+
ChimerDB4BRCATCGA-AR-A1AN-01ACAPZA2chr7

116550365

+METchr7

116409699

+
ChimerDB4KIRPTCGA-G7-6793-01ACAPZA2chr7

116528244

-METchr7

116395409

+
ChimerDB4KIRPTCGA-G7-6793CAPZA2chr7

116528244

+METchr7

116395409

+
ChimerDB4LUADTCGA-78-7220-01ACAPZA2chr7

116528244

-METchr7

116414935

+
ChimerDB4LUADTCGA-78-7220-01ACAPZA2chr7

116528244

+METchr7

116414935

+
ChimerDB4STADTCGA-HU-8238-01ACAPZA2chr7

116502704

+METchr7

116435709

+


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Fusion Gene ORF analysis for CAPZA2-MET

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000466023ENST00000318493CAPZA2chr7

116502704

+METchr7

116435709

+
3UTR-3CDSENST00000466023ENST00000397752CAPZA2chr7

116502704

+METchr7

116435709

+
3UTR-intronENST00000466023ENST00000436117CAPZA2chr7

116502704

+METchr7

116435709

+
3UTR-intronENST00000466023ENST00000495962CAPZA2chr7

116502704

+METchr7

116435709

+
3UTR-intronENST00000466023ENST00000539704CAPZA2chr7

116502704

+METchr7

116435709

+
5CDS-3UTRENST00000361183ENST00000495962CAPZA2chr7

116528244

+METchr7

116395409

+
5CDS-3UTRENST00000458284ENST00000495962CAPZA2chr7

116528244

+METchr7

116395409

+
5CDS-3UTRENST00000490693ENST00000495962CAPZA2chr7

116528244

+METchr7

116395409

+
5CDS-intronENST00000361183ENST00000436117CAPZA2chr7

116550365

+METchr7

116409699

+
5CDS-intronENST00000361183ENST00000436117CAPZA2chr7

116528244

+METchr7

116414935

+
5CDS-intronENST00000361183ENST00000436117CAPZA2chr7

116502704

+METchr7

116435709

+
5CDS-intronENST00000361183ENST00000495962CAPZA2chr7

116550365

+METchr7

116409699

+
5CDS-intronENST00000361183ENST00000495962CAPZA2chr7

116528244

+METchr7

116414935

+
5CDS-intronENST00000361183ENST00000495962CAPZA2chr7

116502704

+METchr7

116435709

+
5CDS-intronENST00000361183ENST00000539704CAPZA2chr7

116550365

+METchr7

116409699

+
5CDS-intronENST00000361183ENST00000539704CAPZA2chr7

116528244

+METchr7

116395409

+
5CDS-intronENST00000361183ENST00000539704CAPZA2chr7

116528244

+METchr7

116414935

+
5CDS-intronENST00000361183ENST00000539704CAPZA2chr7

116502704

+METchr7

116435709

+
5CDS-intronENST00000458284ENST00000436117CAPZA2chr7

116550365

+METchr7

116409699

+
5CDS-intronENST00000458284ENST00000436117CAPZA2chr7

116528244

+METchr7

116414935

+
5CDS-intronENST00000458284ENST00000436117CAPZA2chr7

116502704

+METchr7

116435709

+
5CDS-intronENST00000458284ENST00000495962CAPZA2chr7

116550365

+METchr7

116409699

+
5CDS-intronENST00000458284ENST00000495962CAPZA2chr7

116528244

+METchr7

116414935

+
5CDS-intronENST00000458284ENST00000495962CAPZA2chr7

116502704

+METchr7

116435709

+
5CDS-intronENST00000458284ENST00000539704CAPZA2chr7

116550365

+METchr7

116409699

+
5CDS-intronENST00000458284ENST00000539704CAPZA2chr7

116528244

+METchr7

116395409

+
5CDS-intronENST00000458284ENST00000539704CAPZA2chr7

116528244

+METchr7

116414935

+
5CDS-intronENST00000458284ENST00000539704CAPZA2chr7

116502704

+METchr7

116435709

+
5CDS-intronENST00000490693ENST00000436117CAPZA2chr7

116528244

+METchr7

116414935

+
5CDS-intronENST00000490693ENST00000436117CAPZA2chr7

116502704

+METchr7

116435709

+
5CDS-intronENST00000490693ENST00000495962CAPZA2chr7

116528244

+METchr7

116414935

+
5CDS-intronENST00000490693ENST00000495962CAPZA2chr7

116502704

+METchr7

116435709

+
5CDS-intronENST00000490693ENST00000539704CAPZA2chr7

116528244

+METchr7

116395409

+
5CDS-intronENST00000490693ENST00000539704CAPZA2chr7

116528244

+METchr7

116414935

+
5CDS-intronENST00000490693ENST00000539704CAPZA2chr7

116502704

+METchr7

116435709

+
Frame-shiftENST00000361183ENST00000318493CAPZA2chr7

116528244

+METchr7

116395409

+
Frame-shiftENST00000361183ENST00000397752CAPZA2chr7

116528244

+METchr7

116395409

+
Frame-shiftENST00000361183ENST00000436117CAPZA2chr7

116528244

+METchr7

116395409

+
Frame-shiftENST00000458284ENST00000318493CAPZA2chr7

116550365

+METchr7

116409699

+
Frame-shiftENST00000458284ENST00000318493CAPZA2chr7

116528244

+METchr7

116395409

+
Frame-shiftENST00000458284ENST00000397752CAPZA2chr7

116550365

+METchr7

116409699

+
Frame-shiftENST00000458284ENST00000397752CAPZA2chr7

116528244

+METchr7

116395409

+
Frame-shiftENST00000458284ENST00000436117CAPZA2chr7

116528244

+METchr7

116395409

+
Frame-shiftENST00000490693ENST00000318493CAPZA2chr7

116528244

+METchr7

116395409

+
Frame-shiftENST00000490693ENST00000397752CAPZA2chr7

116528244

+METchr7

116395409

+
Frame-shiftENST00000490693ENST00000436117CAPZA2chr7

116528244

+METchr7

116395409

+
In-frameENST00000361183ENST00000318493CAPZA2chr7

116550365

+METchr7

116409699

+
In-frameENST00000361183ENST00000318493CAPZA2chr7

116528244

+METchr7

116414935

+
In-frameENST00000361183ENST00000318493CAPZA2chr7

116502704

+METchr7

116435709

+
In-frameENST00000361183ENST00000397752CAPZA2chr7

116550365

+METchr7

116409699

+
In-frameENST00000361183ENST00000397752CAPZA2chr7

116528244

+METchr7

116414935

+
In-frameENST00000361183ENST00000397752CAPZA2chr7

116502704

+METchr7

116435709

+
In-frameENST00000458284ENST00000318493CAPZA2chr7

116528244

+METchr7

116414935

+
In-frameENST00000458284ENST00000318493CAPZA2chr7

116502704

+METchr7

116435709

+
In-frameENST00000458284ENST00000397752CAPZA2chr7

116528244

+METchr7

116414935

+
In-frameENST00000458284ENST00000397752CAPZA2chr7

116502704

+METchr7

116435709

+
In-frameENST00000490693ENST00000318493CAPZA2chr7

116528244

+METchr7

116414935

+
In-frameENST00000490693ENST00000318493CAPZA2chr7

116502704

+METchr7

116435709

+
In-frameENST00000490693ENST00000397752CAPZA2chr7

116528244

+METchr7

116414935

+
In-frameENST00000490693ENST00000397752CAPZA2chr7

116502704

+METchr7

116435709

+
intron-3CDSENST00000466023ENST00000318493CAPZA2chr7

116550365

+METchr7

116409699

+
intron-3CDSENST00000466023ENST00000318493CAPZA2chr7

116528244

+METchr7

116395409

+
intron-3CDSENST00000466023ENST00000318493CAPZA2chr7

116528244

+METchr7

116414935

+
intron-3CDSENST00000466023ENST00000397752CAPZA2chr7

116550365

+METchr7

116409699

+
intron-3CDSENST00000466023ENST00000397752CAPZA2chr7

116528244

+METchr7

116395409

+
intron-3CDSENST00000466023ENST00000397752CAPZA2chr7

116528244

+METchr7

116414935

+
intron-3CDSENST00000466023ENST00000436117CAPZA2chr7

116528244

+METchr7

116395409

+
intron-3CDSENST00000490693ENST00000318493CAPZA2chr7

116550365

+METchr7

116409699

+
intron-3CDSENST00000490693ENST00000397752CAPZA2chr7

116550365

+METchr7

116409699

+
intron-3UTRENST00000466023ENST00000495962CAPZA2chr7

116528244

+METchr7

116395409

+
intron-intronENST00000466023ENST00000436117CAPZA2chr7

116550365

+METchr7

116409699

+
intron-intronENST00000466023ENST00000436117CAPZA2chr7

116528244

+METchr7

116414935

+
intron-intronENST00000466023ENST00000495962CAPZA2chr7

116550365

+METchr7

116409699

+
intron-intronENST00000466023ENST00000495962CAPZA2chr7

116528244

+METchr7

116414935

+
intron-intronENST00000466023ENST00000539704CAPZA2chr7

116550365

+METchr7

116409699

+
intron-intronENST00000466023ENST00000539704CAPZA2chr7

116528244

+METchr7

116395409

+
intron-intronENST00000466023ENST00000539704CAPZA2chr7

116528244

+METchr7

116414935

+
intron-intronENST00000490693ENST00000436117CAPZA2chr7

116550365

+METchr7

116409699

+
intron-intronENST00000490693ENST00000495962CAPZA2chr7

116550365

+METchr7

116409699

+
intron-intronENST00000490693ENST00000539704CAPZA2chr7

116550365

+METchr7

116409699

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000361183CAPZA2chr7116550365+ENST00000397752METchr7116409699+45767241002313737
ENST00000361183CAPZA2chr7116550365+ENST00000318493METchr7116409699+25327241002313737
ENST00000361183CAPZA2chr7116528244+ENST00000397752METchr7116414935+36492421001386428
ENST00000361183CAPZA2chr7116528244+ENST00000318493METchr7116414935+16052421001386428
ENST00000458284CAPZA2chr7116528244+ENST00000397752METchr7116414935+3563156141300428
ENST00000458284CAPZA2chr7116528244+ENST00000318493METchr7116414935+1519156141300428
ENST00000490693CAPZA2chr7116528244+ENST00000397752METchr7116414935+3522115121259415
ENST00000490693CAPZA2chr7116528244+ENST00000318493METchr7116414935+1478115121259415

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000361183ENST00000397752CAPZA2chr7116550365+METchr7116409699+0.0004711910.9995289
ENST00000361183ENST00000318493CAPZA2chr7116550365+METchr7116409699+0.0012178890.9987821
ENST00000361183ENST00000397752CAPZA2chr7116528244+METchr7116414935+0.0003189090.9996811
ENST00000361183ENST00000318493CAPZA2chr7116528244+METchr7116414935+0.0006527510.99934727
ENST00000458284ENST00000397752CAPZA2chr7116528244+METchr7116414935+0.0003160450.999684
ENST00000458284ENST00000318493CAPZA2chr7116528244+METchr7116414935+0.0005756890.99942434
ENST00000490693ENST00000397752CAPZA2chr7116528244+METchr7116414935+0.0003022740.9996978
ENST00000490693ENST00000318493CAPZA2chr7116528244+METchr7116414935+0.0005895970.9994104

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Fusion Genomic Features for CAPZA2-MET


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
CAPZA2chr7116528244+METchr7116414934+6.06E-060.9999939
CAPZA2chr7116528244+METchr7116395408+1.50E-060.99999845
CAPZA2chr7116502704+METchr7116435708+7.05E-070.9999993
CAPZA2chr7116550365+METchr7116409698+6.81E-080.9999999
CAPZA2chr7116528244+METchr7116414934+6.06E-060.9999939
CAPZA2chr7116528244+METchr7116395408+1.50E-060.99999845
CAPZA2chr7116502704+METchr7116435708+7.05E-070.9999993
CAPZA2chr7116550365+METchr7116409698+6.81E-080.9999999

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for CAPZA2-MET


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr7:116550365/chr7:116409699)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
CAPZA2

P47755

MET

P08581

FUNCTION: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.FUNCTION: Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of these downstream effectors by MET leads to the activation of several signaling cascades including the RAS-ERK, PI3 kinase-AKT, or PLCgamma-PKC. The RAS-ERK activation is associated with the morphogenetic effects while PI3K/AKT coordinates prosurvival effects. During embryonic development, MET signaling plays a role in gastrulation, development and migration of muscles and neuronal precursors, angiogenesis and kidney formation. In adults, participates in wound healing as well as organ regeneration and tissue remodeling. Promotes also differentiation and proliferation of hematopoietic cells. May regulate cortical bone osteogenesis (By similarity). {ECO:0000250|UniProtKB:P16056}.; FUNCTION: (Microbial infection) Acts as a receptor for Listeria monocytogenes internalin InlB, mediating entry of the pathogen into cells. {ECO:0000269|PubMed:11081636, ECO:0000305|PubMed:17662939, ECO:0000305|PubMed:19900460}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneMETchr7:116502704chr7:116435709ENST00000436117091078_13450765.0DomainProtein kinase
TgeneMETchr7:116502704chr7:116435709ENST000004361170927_5150765.0DomainSema
TgeneMETchr7:116502704chr7:116435709ENST0000043611709563_6550765.0DomainNote=IPT/TIG 1
TgeneMETchr7:116502704chr7:116435709ENST0000043611709657_7390765.0DomainNote=IPT/TIG 2
TgeneMETchr7:116502704chr7:116435709ENST0000043611709742_8360765.0DomainNote=IPT/TIG 3
TgeneMETchr7:116528244chr7:116414935ENST0000031849313211078_134510271409.0DomainProtein kinase
TgeneMETchr7:116528244chr7:116414935ENST0000039775213211078_134510091391.0DomainProtein kinase
TgeneMETchr7:116528244chr7:116414935ENST00000436117091078_13450765.0DomainProtein kinase
TgeneMETchr7:116528244chr7:116414935ENST000004361170927_5150765.0DomainSema
TgeneMETchr7:116528244chr7:116414935ENST0000043611709563_6550765.0DomainNote=IPT/TIG 1
TgeneMETchr7:116528244chr7:116414935ENST0000043611709657_7390765.0DomainNote=IPT/TIG 2
TgeneMETchr7:116528244chr7:116414935ENST0000043611709742_8360765.0DomainNote=IPT/TIG 3
TgeneMETchr7:116550365chr7:116409699ENST0000031849310211078_13458791409.0DomainProtein kinase
TgeneMETchr7:116550365chr7:116409699ENST0000039775210211078_13458611391.0DomainProtein kinase
TgeneMETchr7:116550365chr7:116409699ENST00000436117091078_13450765.0DomainProtein kinase
TgeneMETchr7:116550365chr7:116409699ENST000004361170927_5150765.0DomainSema
TgeneMETchr7:116550365chr7:116409699ENST0000043611709563_6550765.0DomainNote=IPT/TIG 1
TgeneMETchr7:116550365chr7:116409699ENST0000043611709657_7390765.0DomainNote=IPT/TIG 2
TgeneMETchr7:116550365chr7:116409699ENST0000043611709742_8360765.0DomainNote=IPT/TIG 3
TgeneMETchr7:116502704chr7:116435709ENST00000436117091084_10920765.0Nucleotide bindingATP
TgeneMETchr7:116528244chr7:116414935ENST0000031849313211084_109210271409.0Nucleotide bindingATP
TgeneMETchr7:116528244chr7:116414935ENST0000039775213211084_109210091391.0Nucleotide bindingATP
TgeneMETchr7:116528244chr7:116414935ENST00000436117091084_10920765.0Nucleotide bindingATP
TgeneMETchr7:116550365chr7:116409699ENST0000031849310211084_10928791409.0Nucleotide bindingATP
TgeneMETchr7:116550365chr7:116409699ENST0000039775210211084_10928611391.0Nucleotide bindingATP
TgeneMETchr7:116550365chr7:116409699ENST00000436117091084_10920765.0Nucleotide bindingATP
TgeneMETchr7:116502704chr7:116435709ENST000004361170925_9320765.0Topological domainExtracellular
TgeneMETchr7:116502704chr7:116435709ENST0000043611709956_13900765.0Topological domainCytoplasmic
TgeneMETchr7:116528244chr7:116414935ENST000004361170925_9320765.0Topological domainExtracellular
TgeneMETchr7:116528244chr7:116414935ENST0000043611709956_13900765.0Topological domainCytoplasmic
TgeneMETchr7:116550365chr7:116409699ENST000003184931021956_13908791409.0Topological domainCytoplasmic
TgeneMETchr7:116550365chr7:116409699ENST000003977521021956_13908611391.0Topological domainCytoplasmic
TgeneMETchr7:116550365chr7:116409699ENST000004361170925_9320765.0Topological domainExtracellular
TgeneMETchr7:116550365chr7:116409699ENST0000043611709956_13900765.0Topological domainCytoplasmic
TgeneMETchr7:116502704chr7:116435709ENST0000043611709933_9550765.0TransmembraneHelical
TgeneMETchr7:116528244chr7:116414935ENST0000043611709933_9550765.0TransmembraneHelical
TgeneMETchr7:116550365chr7:116409699ENST000003184931021933_9558791409.0TransmembraneHelical
TgeneMETchr7:116550365chr7:116409699ENST000003977521021933_9558611391.0TransmembraneHelical
TgeneMETchr7:116550365chr7:116409699ENST0000043611709933_9550765.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneMETchr7:116502704chr7:116435709ENST0000031849318211078_134512841409.0DomainProtein kinase
TgeneMETchr7:116502704chr7:116435709ENST00000318493182127_51512841409.0DomainSema
TgeneMETchr7:116502704chr7:116435709ENST000003184931821563_65512841409.0DomainNote=IPT/TIG 1
TgeneMETchr7:116502704chr7:116435709ENST000003184931821657_73912841409.0DomainNote=IPT/TIG 2
TgeneMETchr7:116502704chr7:116435709ENST000003184931821742_83612841409.0DomainNote=IPT/TIG 3
TgeneMETchr7:116502704chr7:116435709ENST0000039775218211078_134512661391.0DomainProtein kinase
TgeneMETchr7:116502704chr7:116435709ENST00000397752182127_51512661391.0DomainSema
TgeneMETchr7:116502704chr7:116435709ENST000003977521821563_65512661391.0DomainNote=IPT/TIG 1
TgeneMETchr7:116502704chr7:116435709ENST000003977521821657_73912661391.0DomainNote=IPT/TIG 2
TgeneMETchr7:116502704chr7:116435709ENST000003977521821742_83612661391.0DomainNote=IPT/TIG 3
TgeneMETchr7:116528244chr7:116414935ENST00000318493132127_51510271409.0DomainSema
TgeneMETchr7:116528244chr7:116414935ENST000003184931321563_65510271409.0DomainNote=IPT/TIG 1
TgeneMETchr7:116528244chr7:116414935ENST000003184931321657_73910271409.0DomainNote=IPT/TIG 2
TgeneMETchr7:116528244chr7:116414935ENST000003184931321742_83610271409.0DomainNote=IPT/TIG 3
TgeneMETchr7:116528244chr7:116414935ENST00000397752132127_51510091391.0DomainSema
TgeneMETchr7:116528244chr7:116414935ENST000003977521321563_65510091391.0DomainNote=IPT/TIG 1
TgeneMETchr7:116528244chr7:116414935ENST000003977521321657_73910091391.0DomainNote=IPT/TIG 2
TgeneMETchr7:116528244chr7:116414935ENST000003977521321742_83610091391.0DomainNote=IPT/TIG 3
TgeneMETchr7:116550365chr7:116409699ENST00000318493102127_5158791409.0DomainSema
TgeneMETchr7:116550365chr7:116409699ENST000003184931021563_6558791409.0DomainNote=IPT/TIG 1
TgeneMETchr7:116550365chr7:116409699ENST000003184931021657_7398791409.0DomainNote=IPT/TIG 2
TgeneMETchr7:116550365chr7:116409699ENST000003184931021742_8368791409.0DomainNote=IPT/TIG 3
TgeneMETchr7:116550365chr7:116409699ENST00000397752102127_5158611391.0DomainSema
TgeneMETchr7:116550365chr7:116409699ENST000003977521021563_6558611391.0DomainNote=IPT/TIG 1
TgeneMETchr7:116550365chr7:116409699ENST000003977521021657_7398611391.0DomainNote=IPT/TIG 2
TgeneMETchr7:116550365chr7:116409699ENST000003977521021742_8368611391.0DomainNote=IPT/TIG 3
TgeneMETchr7:116502704chr7:116435709ENST0000031849318211084_109212841409.0Nucleotide bindingATP
TgeneMETchr7:116502704chr7:116435709ENST0000039775218211084_109212661391.0Nucleotide bindingATP
TgeneMETchr7:116502704chr7:116435709ENST00000318493182125_93212841409.0Topological domainExtracellular
TgeneMETchr7:116502704chr7:116435709ENST000003184931821956_139012841409.0Topological domainCytoplasmic
TgeneMETchr7:116502704chr7:116435709ENST00000397752182125_93212661391.0Topological domainExtracellular
TgeneMETchr7:116502704chr7:116435709ENST000003977521821956_139012661391.0Topological domainCytoplasmic
TgeneMETchr7:116528244chr7:116414935ENST00000318493132125_93210271409.0Topological domainExtracellular
TgeneMETchr7:116528244chr7:116414935ENST000003184931321956_139010271409.0Topological domainCytoplasmic
TgeneMETchr7:116528244chr7:116414935ENST00000397752132125_93210091391.0Topological domainExtracellular
TgeneMETchr7:116528244chr7:116414935ENST000003977521321956_139010091391.0Topological domainCytoplasmic
TgeneMETchr7:116550365chr7:116409699ENST00000318493102125_9328791409.0Topological domainExtracellular
TgeneMETchr7:116550365chr7:116409699ENST00000397752102125_9328611391.0Topological domainExtracellular
TgeneMETchr7:116502704chr7:116435709ENST000003184931821933_95512841409.0TransmembraneHelical
TgeneMETchr7:116502704chr7:116435709ENST000003977521821933_95512661391.0TransmembraneHelical
TgeneMETchr7:116528244chr7:116414935ENST000003184931321933_95510271409.0TransmembraneHelical
TgeneMETchr7:116528244chr7:116414935ENST000003977521321933_95510091391.0TransmembraneHelical


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Fusion Gene Sequence for CAPZA2-MET


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>12985_12985_1_CAPZA2-MET_CAPZA2_chr7_116528244_ENST00000361183_MET_chr7_116414935_ENST00000318493_length(transcript)=1605nt_BP=242nt
CCCGGGGTGCGCGTGCGCGGCGGCCTGAGCGGCGGGCCCCTCCCTTAGCGGGGGCGCGCGGCGCTGAGGACCGCACGGAAACGGGGAAGT
CAGGTGGCCGCTGCCGCCGCCGCCGCCGCGGTTTGTCGCCAGAAGGAAGATGGCGGATCTGGAGGAGCAGTTGTCTGATGAAGAGAAGGT
GCGTATAGCAGCAAAATTCATCATTCATGCCCCTCCTGGAGAATTTAATGAGGTTTTCAATGATCAGTTTCCTAATTCATCTCAGAACGG
TTCATGCCGACAAGTGCAGTATCCTCTGACAGACATGTCCCCCATCCTAACTAGTGGGGACTCTGATATATCCAGTCCATTACTGCAAAA
TACTGTCCACATTGACCTCAGTGCTCTAAATCCAGAGCTGGTCCAGGCAGTGCAGCATGTAGTGATTGGGCCCAGTAGCCTGATTGTGCA
TTTCAATGAAGTCATAGGAAGAGGGCATTTTGGTTGTGTATATCATGGGACTTTGTTGGACAATGATGGCAAGAAAATTCACTGTGCTGT
GAAATCCTTGAACAGAATCACTGACATAGGAGAAGTTTCCCAATTTCTGACCGAGGGAATCATCATGAAAGATTTTAGTCATCCCAATGT
CCTCTCGCTCCTGGGAATCTGCCTGCGAAGTGAAGGGTCTCCGCTGGTGGTCCTACCATACATGAAACATGGAGATCTTCGAAATTTCAT
TCGAAATGAGACTCATAATCCAACTGTAAAAGATCTTATTGGCTTTGGTCTTCAAGTAGCCAAAGGCATGAAATATCTTGCAAGCAAAAA
GTTTGTCCACAGAGACTTGGCTGCAAGAAACTGTATGCTGGATGAAAAATTCACAGTCAAGGTTGCTGATTTTGGTCTTGCCAGAGACAT
GTATGATAAAGAATACTATAGTGTACACAACAAAACAGGTGCAAAGCTGCCAGTGAAGTGGATGGCTTTGGAAAGTCTGCAAACTCAAAA
GTTTACCACCAAGTCAGATGTGTGGTCCTTTGGCGTGCTCCTCTGGGAGCTGATGACAAGAGGAGCCCCACCTTATCCTGACGTAAACAC
CTTTGATATAACTGTTTACTTGTTGCAAGGGAGAAGACTCCTACAACCCGAATACTGCCCAGACCCCTTATATGAAGTAATGCTAAAATG
CTGGCACCCTAAAGCCGAAATGCGCCCATCCTTTTCTGAACTGGTGTCCCGGATATCAGCGATCTTCTCTACTTTCATTGGGGAGCACTA
TGTCCATGTGAACGCTACTTATGTGAACGTAAAATGTGTCGCTCCGTATCCTTCTCTGTTGTCATCAGAAGATAACGCTGATGATGAGGT
GGACACACGACCAGCCTCCTTCTGGGAGACATCATAGTGCTAGTACTATGTCAAAGCAACAGTCCACACTTTGTCCAATGGTTTTTTCAC
TGCCTGACCTTTAAAAGGCCATCGATATTCTTTGCTCTTGCCAAAATTGCACTATTATAGGACTTGTATTGTTATTTAAATTACTGGATT

>12985_12985_1_CAPZA2-MET_CAPZA2_chr7_116528244_ENST00000361183_MET_chr7_116414935_ENST00000318493_length(amino acids)=428AA_BP=47
MPPPPPRFVARRKMADLEEQLSDEEKVRIAAKFIIHAPPGEFNEVFNDQFPNSSQNGSCRQVQYPLTDMSPILTSGDSDISSPLLQNTVH
IDLSALNPELVQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSL
LGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDK
EYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHP

--------------------------------------------------------------
>12985_12985_2_CAPZA2-MET_CAPZA2_chr7_116528244_ENST00000361183_MET_chr7_116414935_ENST00000397752_length(transcript)=3649nt_BP=242nt
CCCGGGGTGCGCGTGCGCGGCGGCCTGAGCGGCGGGCCCCTCCCTTAGCGGGGGCGCGCGGCGCTGAGGACCGCACGGAAACGGGGAAGT
CAGGTGGCCGCTGCCGCCGCCGCCGCCGCGGTTTGTCGCCAGAAGGAAGATGGCGGATCTGGAGGAGCAGTTGTCTGATGAAGAGAAGGT
GCGTATAGCAGCAAAATTCATCATTCATGCCCCTCCTGGAGAATTTAATGAGGTTTTCAATGATCAGTTTCCTAATTCATCTCAGAACGG
TTCATGCCGACAAGTGCAGTATCCTCTGACAGACATGTCCCCCATCCTAACTAGTGGGGACTCTGATATATCCAGTCCATTACTGCAAAA
TACTGTCCACATTGACCTCAGTGCTCTAAATCCAGAGCTGGTCCAGGCAGTGCAGCATGTAGTGATTGGGCCCAGTAGCCTGATTGTGCA
TTTCAATGAAGTCATAGGAAGAGGGCATTTTGGTTGTGTATATCATGGGACTTTGTTGGACAATGATGGCAAGAAAATTCACTGTGCTGT
GAAATCCTTGAACAGAATCACTGACATAGGAGAAGTTTCCCAATTTCTGACCGAGGGAATCATCATGAAAGATTTTAGTCATCCCAATGT
CCTCTCGCTCCTGGGAATCTGCCTGCGAAGTGAAGGGTCTCCGCTGGTGGTCCTACCATACATGAAACATGGAGATCTTCGAAATTTCAT
TCGAAATGAGACTCATAATCCAACTGTAAAAGATCTTATTGGCTTTGGTCTTCAAGTAGCCAAAGGCATGAAATATCTTGCAAGCAAAAA
GTTTGTCCACAGAGACTTGGCTGCAAGAAACTGTATGCTGGATGAAAAATTCACAGTCAAGGTTGCTGATTTTGGTCTTGCCAGAGACAT
GTATGATAAAGAATACTATAGTGTACACAACAAAACAGGTGCAAAGCTGCCAGTGAAGTGGATGGCTTTGGAAAGTCTGCAAACTCAAAA
GTTTACCACCAAGTCAGATGTGTGGTCCTTTGGCGTGCTCCTCTGGGAGCTGATGACAAGAGGAGCCCCACCTTATCCTGACGTAAACAC
CTTTGATATAACTGTTTACTTGTTGCAAGGGAGAAGACTCCTACAACCCGAATACTGCCCAGACCCCTTATATGAAGTAATGCTAAAATG
CTGGCACCCTAAAGCCGAAATGCGCCCATCCTTTTCTGAACTGGTGTCCCGGATATCAGCGATCTTCTCTACTTTCATTGGGGAGCACTA
TGTCCATGTGAACGCTACTTATGTGAACGTAAAATGTGTCGCTCCGTATCCTTCTCTGTTGTCATCAGAAGATAACGCTGATGATGAGGT
GGACACACGACCAGCCTCCTTCTGGGAGACATCATAGTGCTAGTACTATGTCAAAGCAACAGTCCACACTTTGTCCAATGGTTTTTTCAC
TGCCTGACCTTTAAAAGGCCATCGATATTCTTTGCTCTTGCCAAAATTGCACTATTATAGGACTTGTATTGTTATTTAAATTACTGGATT
CTAAGGAATTTCTTATCTGACAGAGCATCAGAACCAGAGGCTTGGTCCCACAGGCCACGGACCAATGGCCTGCAGCCGTGACAACACTCC
TGTCATATTGGAGTCCAAAACTTGAATTCTGGGTTGAATTTTTTAAAAATCAGGTACCACTTGATTTCATATGGGAAATTGAAGCAGGAA
ATATTGAGGGCTTCTTGATCACAGAAAACTCAGAAGAGATAGTAATGCTCAGGACAGGAGCGGCAGCCCCAGAACAGGCCACTCATTTAG
AATTCTAGTGTTTCAAAACACTTTTGTGTGTTGTATGGTCAATAACATTTTTCATTACTGATGGTGTCATTCACCCATTAGGTAAACATT
CCCTTTTAAATGTTTGTTTGTTTTTTGAGACAGGATCTCACTCTGTTGCCAGGGCTGTAGTGCAGTGGTGTGATCATAGCTCACTGCAAC
CTCCACCTCCCAGGCTCAAGCCTCCCGAATAGCTGGGACTACAGGCGCACACCACCATCCCCGGCTAATTTTTGTATTTTTTGTAGAGAC
GGGGTTTTGCCATGTTGCCAAGGCTGGTTTCAAACTCCTGGACTCAAGAAATCCACCCACCTCAGCCTCCCAAAGTGCTAGGATTACAGG
CATGAGCCACTGCGCCCAGCCCTTATAAATTTTTGTATAGACATTCCTTTGGTTGGAAGAATATTTATAGGCAATACAGTCAAAGTTTCA
AAATAGCATCACACAAAACATGTTTATAAATGAACAGGATGTAATGTACATAGATGACATTAAGAAAATTTGTATGAAATAATTTAGTCA
TCATGAAATATTTAGTTGTCATATAAAAACCCACTGTTTGAGAATGATGCTACTCTGATCTAATGAATGTGAACATGTAGATGTTTTGTG
TGTATTTTTTTAAATGAAAACTCAAAATAAGACAAGTAATTTGTTGATAAATATTTTTAAAGATAACTCAGCATGTTTGTAAAGCAGGAT
ACATTTTACTAAAAGGTTCATTGGTTCCAATCACAGCTCATAGGTAGAGCAAAGAAAGGGTGGATGGATTGAAAAGATTAGCCTCTGTCT
CGGTGGCAGGTTCCCACCTCGCAAGCAATTGGAAACAAAACTTTTGGGGAGTTTTATTTTGCATTAGGGTGTGTTTTATGTTAAGCAAAA
CATACTTTAGAAACAAATGAAAAAGGCAATTGAAAATCCCAGCTATTTCACCTAGATGGAATAGCCACCCTGAGCAGAACTTTGTGATGC
TTCATTCTGTGGAATTTTGTGCTTGCTACTGTATAGTGCATGTGGTGTAGGTTACTCTAACTGGTTTTGTCGACGTAAACATTTAAAGTG
TTATATTTTTTATAAAAATGTTTATTTTTAATGATATGAGAAAAATTTTGTTAGGCCACAAAAACACTGCACTGTGAACATTTTAGAAAA
GGTATGTCAGACTGGGATTAATGACAGCATGATTTTCAATGACTGTAAATTGCGATAAGGAAATGTACTGATTGCCAATACACCCCACCC
TCATTACATCATCAGGACTTGAAGCCAAGGGTTAACCCAGCAAGCTACAAAGAGGGTGTGTCACACTGAAACTCAATAGTTGAGTTTGGC
TGTTGTTGCAGGAAAATGATTATAACTAAAAGCTCTCTGATAGTGCAGAGACTTACCAGAAGACACAAGGAATTGTACTGAAGAGCTATT
ACAATCCAAATATTGCCGTTTCATAAATGTAATAAGTAATACTAATTCACAGAGTATTGTAAATGGTGGATGACAAAAGAAAATCTGCTC
TGTGGAAAGAAAGAACTGTCTCTACCAGGGTCAAGAGCATGAACGCATCAATAGAAAGAACTCGGGGAAACATCCCATCAACAGGACTAC
ACACTTGTATATACATTCTTGAGAACACTGCAATGTGAAAATCACGTTTGCTATTTATAAACTTGTCCTTAGATTAATGTGTCTGGACAG
ATTGTGGGAGTAAGTGATTCTTCTAAGAATTAGATACTTGTCACTGCCTATACCTGCAGCTGAACTGAATGGTACTTCGTATGTTAATAG

>12985_12985_2_CAPZA2-MET_CAPZA2_chr7_116528244_ENST00000361183_MET_chr7_116414935_ENST00000397752_length(amino acids)=428AA_BP=47
MPPPPPRFVARRKMADLEEQLSDEEKVRIAAKFIIHAPPGEFNEVFNDQFPNSSQNGSCRQVQYPLTDMSPILTSGDSDISSPLLQNTVH
IDLSALNPELVQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSL
LGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDK
EYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHP

--------------------------------------------------------------
>12985_12985_3_CAPZA2-MET_CAPZA2_chr7_116528244_ENST00000458284_MET_chr7_116414935_ENST00000318493_length(transcript)=1519nt_BP=156nt
AAGTCAGGTGGCCGCTGCCGCCGCCGCCGCCGCGGTTTGTCGCCAGAAGGAAGATGGCGGATCTGGAGGAGCAGTTGTCTGATGAAGAGA
AGGTGCGTATAGCAGCAAAATTCATCATTCATGCCCCTCCTGGAGAATTTAATGAGGTTTTCAATGATCAGTTTCCTAATTCATCTCAGA
ACGGTTCATGCCGACAAGTGCAGTATCCTCTGACAGACATGTCCCCCATCCTAACTAGTGGGGACTCTGATATATCCAGTCCATTACTGC
AAAATACTGTCCACATTGACCTCAGTGCTCTAAATCCAGAGCTGGTCCAGGCAGTGCAGCATGTAGTGATTGGGCCCAGTAGCCTGATTG
TGCATTTCAATGAAGTCATAGGAAGAGGGCATTTTGGTTGTGTATATCATGGGACTTTGTTGGACAATGATGGCAAGAAAATTCACTGTG
CTGTGAAATCCTTGAACAGAATCACTGACATAGGAGAAGTTTCCCAATTTCTGACCGAGGGAATCATCATGAAAGATTTTAGTCATCCCA
ATGTCCTCTCGCTCCTGGGAATCTGCCTGCGAAGTGAAGGGTCTCCGCTGGTGGTCCTACCATACATGAAACATGGAGATCTTCGAAATT
TCATTCGAAATGAGACTCATAATCCAACTGTAAAAGATCTTATTGGCTTTGGTCTTCAAGTAGCCAAAGGCATGAAATATCTTGCAAGCA
AAAAGTTTGTCCACAGAGACTTGGCTGCAAGAAACTGTATGCTGGATGAAAAATTCACAGTCAAGGTTGCTGATTTTGGTCTTGCCAGAG
ACATGTATGATAAAGAATACTATAGTGTACACAACAAAACAGGTGCAAAGCTGCCAGTGAAGTGGATGGCTTTGGAAAGTCTGCAAACTC
AAAAGTTTACCACCAAGTCAGATGTGTGGTCCTTTGGCGTGCTCCTCTGGGAGCTGATGACAAGAGGAGCCCCACCTTATCCTGACGTAA
ACACCTTTGATATAACTGTTTACTTGTTGCAAGGGAGAAGACTCCTACAACCCGAATACTGCCCAGACCCCTTATATGAAGTAATGCTAA
AATGCTGGCACCCTAAAGCCGAAATGCGCCCATCCTTTTCTGAACTGGTGTCCCGGATATCAGCGATCTTCTCTACTTTCATTGGGGAGC
ACTATGTCCATGTGAACGCTACTTATGTGAACGTAAAATGTGTCGCTCCGTATCCTTCTCTGTTGTCATCAGAAGATAACGCTGATGATG
AGGTGGACACACGACCAGCCTCCTTCTGGGAGACATCATAGTGCTAGTACTATGTCAAAGCAACAGTCCACACTTTGTCCAATGGTTTTT
TCACTGCCTGACCTTTAAAAGGCCATCGATATTCTTTGCTCTTGCCAAAATTGCACTATTATAGGACTTGTATTGTTATTTAAATTACTG

>12985_12985_3_CAPZA2-MET_CAPZA2_chr7_116528244_ENST00000458284_MET_chr7_116414935_ENST00000318493_length(amino acids)=428AA_BP=47
MPPPPPRFVARRKMADLEEQLSDEEKVRIAAKFIIHAPPGEFNEVFNDQFPNSSQNGSCRQVQYPLTDMSPILTSGDSDISSPLLQNTVH
IDLSALNPELVQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSL
LGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDK
EYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHP

--------------------------------------------------------------
>12985_12985_4_CAPZA2-MET_CAPZA2_chr7_116528244_ENST00000458284_MET_chr7_116414935_ENST00000397752_length(transcript)=3563nt_BP=156nt
AAGTCAGGTGGCCGCTGCCGCCGCCGCCGCCGCGGTTTGTCGCCAGAAGGAAGATGGCGGATCTGGAGGAGCAGTTGTCTGATGAAGAGA
AGGTGCGTATAGCAGCAAAATTCATCATTCATGCCCCTCCTGGAGAATTTAATGAGGTTTTCAATGATCAGTTTCCTAATTCATCTCAGA
ACGGTTCATGCCGACAAGTGCAGTATCCTCTGACAGACATGTCCCCCATCCTAACTAGTGGGGACTCTGATATATCCAGTCCATTACTGC
AAAATACTGTCCACATTGACCTCAGTGCTCTAAATCCAGAGCTGGTCCAGGCAGTGCAGCATGTAGTGATTGGGCCCAGTAGCCTGATTG
TGCATTTCAATGAAGTCATAGGAAGAGGGCATTTTGGTTGTGTATATCATGGGACTTTGTTGGACAATGATGGCAAGAAAATTCACTGTG
CTGTGAAATCCTTGAACAGAATCACTGACATAGGAGAAGTTTCCCAATTTCTGACCGAGGGAATCATCATGAAAGATTTTAGTCATCCCA
ATGTCCTCTCGCTCCTGGGAATCTGCCTGCGAAGTGAAGGGTCTCCGCTGGTGGTCCTACCATACATGAAACATGGAGATCTTCGAAATT
TCATTCGAAATGAGACTCATAATCCAACTGTAAAAGATCTTATTGGCTTTGGTCTTCAAGTAGCCAAAGGCATGAAATATCTTGCAAGCA
AAAAGTTTGTCCACAGAGACTTGGCTGCAAGAAACTGTATGCTGGATGAAAAATTCACAGTCAAGGTTGCTGATTTTGGTCTTGCCAGAG
ACATGTATGATAAAGAATACTATAGTGTACACAACAAAACAGGTGCAAAGCTGCCAGTGAAGTGGATGGCTTTGGAAAGTCTGCAAACTC
AAAAGTTTACCACCAAGTCAGATGTGTGGTCCTTTGGCGTGCTCCTCTGGGAGCTGATGACAAGAGGAGCCCCACCTTATCCTGACGTAA
ACACCTTTGATATAACTGTTTACTTGTTGCAAGGGAGAAGACTCCTACAACCCGAATACTGCCCAGACCCCTTATATGAAGTAATGCTAA
AATGCTGGCACCCTAAAGCCGAAATGCGCCCATCCTTTTCTGAACTGGTGTCCCGGATATCAGCGATCTTCTCTACTTTCATTGGGGAGC
ACTATGTCCATGTGAACGCTACTTATGTGAACGTAAAATGTGTCGCTCCGTATCCTTCTCTGTTGTCATCAGAAGATAACGCTGATGATG
AGGTGGACACACGACCAGCCTCCTTCTGGGAGACATCATAGTGCTAGTACTATGTCAAAGCAACAGTCCACACTTTGTCCAATGGTTTTT
TCACTGCCTGACCTTTAAAAGGCCATCGATATTCTTTGCTCTTGCCAAAATTGCACTATTATAGGACTTGTATTGTTATTTAAATTACTG
GATTCTAAGGAATTTCTTATCTGACAGAGCATCAGAACCAGAGGCTTGGTCCCACAGGCCACGGACCAATGGCCTGCAGCCGTGACAACA
CTCCTGTCATATTGGAGTCCAAAACTTGAATTCTGGGTTGAATTTTTTAAAAATCAGGTACCACTTGATTTCATATGGGAAATTGAAGCA
GGAAATATTGAGGGCTTCTTGATCACAGAAAACTCAGAAGAGATAGTAATGCTCAGGACAGGAGCGGCAGCCCCAGAACAGGCCACTCAT
TTAGAATTCTAGTGTTTCAAAACACTTTTGTGTGTTGTATGGTCAATAACATTTTTCATTACTGATGGTGTCATTCACCCATTAGGTAAA
CATTCCCTTTTAAATGTTTGTTTGTTTTTTGAGACAGGATCTCACTCTGTTGCCAGGGCTGTAGTGCAGTGGTGTGATCATAGCTCACTG
CAACCTCCACCTCCCAGGCTCAAGCCTCCCGAATAGCTGGGACTACAGGCGCACACCACCATCCCCGGCTAATTTTTGTATTTTTTGTAG
AGACGGGGTTTTGCCATGTTGCCAAGGCTGGTTTCAAACTCCTGGACTCAAGAAATCCACCCACCTCAGCCTCCCAAAGTGCTAGGATTA
CAGGCATGAGCCACTGCGCCCAGCCCTTATAAATTTTTGTATAGACATTCCTTTGGTTGGAAGAATATTTATAGGCAATACAGTCAAAGT
TTCAAAATAGCATCACACAAAACATGTTTATAAATGAACAGGATGTAATGTACATAGATGACATTAAGAAAATTTGTATGAAATAATTTA
GTCATCATGAAATATTTAGTTGTCATATAAAAACCCACTGTTTGAGAATGATGCTACTCTGATCTAATGAATGTGAACATGTAGATGTTT
TGTGTGTATTTTTTTAAATGAAAACTCAAAATAAGACAAGTAATTTGTTGATAAATATTTTTAAAGATAACTCAGCATGTTTGTAAAGCA
GGATACATTTTACTAAAAGGTTCATTGGTTCCAATCACAGCTCATAGGTAGAGCAAAGAAAGGGTGGATGGATTGAAAAGATTAGCCTCT
GTCTCGGTGGCAGGTTCCCACCTCGCAAGCAATTGGAAACAAAACTTTTGGGGAGTTTTATTTTGCATTAGGGTGTGTTTTATGTTAAGC
AAAACATACTTTAGAAACAAATGAAAAAGGCAATTGAAAATCCCAGCTATTTCACCTAGATGGAATAGCCACCCTGAGCAGAACTTTGTG
ATGCTTCATTCTGTGGAATTTTGTGCTTGCTACTGTATAGTGCATGTGGTGTAGGTTACTCTAACTGGTTTTGTCGACGTAAACATTTAA
AGTGTTATATTTTTTATAAAAATGTTTATTTTTAATGATATGAGAAAAATTTTGTTAGGCCACAAAAACACTGCACTGTGAACATTTTAG
AAAAGGTATGTCAGACTGGGATTAATGACAGCATGATTTTCAATGACTGTAAATTGCGATAAGGAAATGTACTGATTGCCAATACACCCC
ACCCTCATTACATCATCAGGACTTGAAGCCAAGGGTTAACCCAGCAAGCTACAAAGAGGGTGTGTCACACTGAAACTCAATAGTTGAGTT
TGGCTGTTGTTGCAGGAAAATGATTATAACTAAAAGCTCTCTGATAGTGCAGAGACTTACCAGAAGACACAAGGAATTGTACTGAAGAGC
TATTACAATCCAAATATTGCCGTTTCATAAATGTAATAAGTAATACTAATTCACAGAGTATTGTAAATGGTGGATGACAAAAGAAAATCT
GCTCTGTGGAAAGAAAGAACTGTCTCTACCAGGGTCAAGAGCATGAACGCATCAATAGAAAGAACTCGGGGAAACATCCCATCAACAGGA
CTACACACTTGTATATACATTCTTGAGAACACTGCAATGTGAAAATCACGTTTGCTATTTATAAACTTGTCCTTAGATTAATGTGTCTGG
ACAGATTGTGGGAGTAAGTGATTCTTCTAAGAATTAGATACTTGTCACTGCCTATACCTGCAGCTGAACTGAATGGTACTTCGTATGTTA

>12985_12985_4_CAPZA2-MET_CAPZA2_chr7_116528244_ENST00000458284_MET_chr7_116414935_ENST00000397752_length(amino acids)=428AA_BP=47
MPPPPPRFVARRKMADLEEQLSDEEKVRIAAKFIIHAPPGEFNEVFNDQFPNSSQNGSCRQVQYPLTDMSPILTSGDSDISSPLLQNTVH
IDLSALNPELVQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSL
LGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDK
EYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHP

--------------------------------------------------------------
>12985_12985_5_CAPZA2-MET_CAPZA2_chr7_116528244_ENST00000490693_MET_chr7_116414935_ENST00000318493_length(transcript)=1478nt_BP=115nt
GCCAGAAGGAAGATGGCGGATCTGGAGGAGCAGTTGTCTGATGAAGAGAAGGTGCGTATAGCAGCAAAATTCATCATTCATGCCCCTCCT
GGAGAATTTAATGAGGTTTTCAATGATCAGTTTCCTAATTCATCTCAGAACGGTTCATGCCGACAAGTGCAGTATCCTCTGACAGACATG
TCCCCCATCCTAACTAGTGGGGACTCTGATATATCCAGTCCATTACTGCAAAATACTGTCCACATTGACCTCAGTGCTCTAAATCCAGAG
CTGGTCCAGGCAGTGCAGCATGTAGTGATTGGGCCCAGTAGCCTGATTGTGCATTTCAATGAAGTCATAGGAAGAGGGCATTTTGGTTGT
GTATATCATGGGACTTTGTTGGACAATGATGGCAAGAAAATTCACTGTGCTGTGAAATCCTTGAACAGAATCACTGACATAGGAGAAGTT
TCCCAATTTCTGACCGAGGGAATCATCATGAAAGATTTTAGTCATCCCAATGTCCTCTCGCTCCTGGGAATCTGCCTGCGAAGTGAAGGG
TCTCCGCTGGTGGTCCTACCATACATGAAACATGGAGATCTTCGAAATTTCATTCGAAATGAGACTCATAATCCAACTGTAAAAGATCTT
ATTGGCTTTGGTCTTCAAGTAGCCAAAGGCATGAAATATCTTGCAAGCAAAAAGTTTGTCCACAGAGACTTGGCTGCAAGAAACTGTATG
CTGGATGAAAAATTCACAGTCAAGGTTGCTGATTTTGGTCTTGCCAGAGACATGTATGATAAAGAATACTATAGTGTACACAACAAAACA
GGTGCAAAGCTGCCAGTGAAGTGGATGGCTTTGGAAAGTCTGCAAACTCAAAAGTTTACCACCAAGTCAGATGTGTGGTCCTTTGGCGTG
CTCCTCTGGGAGCTGATGACAAGAGGAGCCCCACCTTATCCTGACGTAAACACCTTTGATATAACTGTTTACTTGTTGCAAGGGAGAAGA
CTCCTACAACCCGAATACTGCCCAGACCCCTTATATGAAGTAATGCTAAAATGCTGGCACCCTAAAGCCGAAATGCGCCCATCCTTTTCT
GAACTGGTGTCCCGGATATCAGCGATCTTCTCTACTTTCATTGGGGAGCACTATGTCCATGTGAACGCTACTTATGTGAACGTAAAATGT
GTCGCTCCGTATCCTTCTCTGTTGTCATCAGAAGATAACGCTGATGATGAGGTGGACACACGACCAGCCTCCTTCTGGGAGACATCATAG
TGCTAGTACTATGTCAAAGCAACAGTCCACACTTTGTCCAATGGTTTTTTCACTGCCTGACCTTTAAAAGGCCATCGATATTCTTTGCTC
TTGCCAAAATTGCACTATTATAGGACTTGTATTGTTATTTAAATTACTGGATTCTAAGGAATTTCTTATCTGACAGAGCATCAGAACCAG

>12985_12985_5_CAPZA2-MET_CAPZA2_chr7_116528244_ENST00000490693_MET_chr7_116414935_ENST00000318493_length(amino acids)=415AA_BP=34
MADLEEQLSDEEKVRIAAKFIIHAPPGEFNEVFNDQFPNSSQNGSCRQVQYPLTDMSPILTSGDSDISSPLLQNTVHIDLSALNPELVQA
VQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLV
VLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKL
PVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVS

--------------------------------------------------------------
>12985_12985_6_CAPZA2-MET_CAPZA2_chr7_116528244_ENST00000490693_MET_chr7_116414935_ENST00000397752_length(transcript)=3522nt_BP=115nt
GCCAGAAGGAAGATGGCGGATCTGGAGGAGCAGTTGTCTGATGAAGAGAAGGTGCGTATAGCAGCAAAATTCATCATTCATGCCCCTCCT
GGAGAATTTAATGAGGTTTTCAATGATCAGTTTCCTAATTCATCTCAGAACGGTTCATGCCGACAAGTGCAGTATCCTCTGACAGACATG
TCCCCCATCCTAACTAGTGGGGACTCTGATATATCCAGTCCATTACTGCAAAATACTGTCCACATTGACCTCAGTGCTCTAAATCCAGAG
CTGGTCCAGGCAGTGCAGCATGTAGTGATTGGGCCCAGTAGCCTGATTGTGCATTTCAATGAAGTCATAGGAAGAGGGCATTTTGGTTGT
GTATATCATGGGACTTTGTTGGACAATGATGGCAAGAAAATTCACTGTGCTGTGAAATCCTTGAACAGAATCACTGACATAGGAGAAGTT
TCCCAATTTCTGACCGAGGGAATCATCATGAAAGATTTTAGTCATCCCAATGTCCTCTCGCTCCTGGGAATCTGCCTGCGAAGTGAAGGG
TCTCCGCTGGTGGTCCTACCATACATGAAACATGGAGATCTTCGAAATTTCATTCGAAATGAGACTCATAATCCAACTGTAAAAGATCTT
ATTGGCTTTGGTCTTCAAGTAGCCAAAGGCATGAAATATCTTGCAAGCAAAAAGTTTGTCCACAGAGACTTGGCTGCAAGAAACTGTATG
CTGGATGAAAAATTCACAGTCAAGGTTGCTGATTTTGGTCTTGCCAGAGACATGTATGATAAAGAATACTATAGTGTACACAACAAAACA
GGTGCAAAGCTGCCAGTGAAGTGGATGGCTTTGGAAAGTCTGCAAACTCAAAAGTTTACCACCAAGTCAGATGTGTGGTCCTTTGGCGTG
CTCCTCTGGGAGCTGATGACAAGAGGAGCCCCACCTTATCCTGACGTAAACACCTTTGATATAACTGTTTACTTGTTGCAAGGGAGAAGA
CTCCTACAACCCGAATACTGCCCAGACCCCTTATATGAAGTAATGCTAAAATGCTGGCACCCTAAAGCCGAAATGCGCCCATCCTTTTCT
GAACTGGTGTCCCGGATATCAGCGATCTTCTCTACTTTCATTGGGGAGCACTATGTCCATGTGAACGCTACTTATGTGAACGTAAAATGT
GTCGCTCCGTATCCTTCTCTGTTGTCATCAGAAGATAACGCTGATGATGAGGTGGACACACGACCAGCCTCCTTCTGGGAGACATCATAG
TGCTAGTACTATGTCAAAGCAACAGTCCACACTTTGTCCAATGGTTTTTTCACTGCCTGACCTTTAAAAGGCCATCGATATTCTTTGCTC
TTGCCAAAATTGCACTATTATAGGACTTGTATTGTTATTTAAATTACTGGATTCTAAGGAATTTCTTATCTGACAGAGCATCAGAACCAG
AGGCTTGGTCCCACAGGCCACGGACCAATGGCCTGCAGCCGTGACAACACTCCTGTCATATTGGAGTCCAAAACTTGAATTCTGGGTTGA
ATTTTTTAAAAATCAGGTACCACTTGATTTCATATGGGAAATTGAAGCAGGAAATATTGAGGGCTTCTTGATCACAGAAAACTCAGAAGA
GATAGTAATGCTCAGGACAGGAGCGGCAGCCCCAGAACAGGCCACTCATTTAGAATTCTAGTGTTTCAAAACACTTTTGTGTGTTGTATG
GTCAATAACATTTTTCATTACTGATGGTGTCATTCACCCATTAGGTAAACATTCCCTTTTAAATGTTTGTTTGTTTTTTGAGACAGGATC
TCACTCTGTTGCCAGGGCTGTAGTGCAGTGGTGTGATCATAGCTCACTGCAACCTCCACCTCCCAGGCTCAAGCCTCCCGAATAGCTGGG
ACTACAGGCGCACACCACCATCCCCGGCTAATTTTTGTATTTTTTGTAGAGACGGGGTTTTGCCATGTTGCCAAGGCTGGTTTCAAACTC
CTGGACTCAAGAAATCCACCCACCTCAGCCTCCCAAAGTGCTAGGATTACAGGCATGAGCCACTGCGCCCAGCCCTTATAAATTTTTGTA
TAGACATTCCTTTGGTTGGAAGAATATTTATAGGCAATACAGTCAAAGTTTCAAAATAGCATCACACAAAACATGTTTATAAATGAACAG
GATGTAATGTACATAGATGACATTAAGAAAATTTGTATGAAATAATTTAGTCATCATGAAATATTTAGTTGTCATATAAAAACCCACTGT
TTGAGAATGATGCTACTCTGATCTAATGAATGTGAACATGTAGATGTTTTGTGTGTATTTTTTTAAATGAAAACTCAAAATAAGACAAGT
AATTTGTTGATAAATATTTTTAAAGATAACTCAGCATGTTTGTAAAGCAGGATACATTTTACTAAAAGGTTCATTGGTTCCAATCACAGC
TCATAGGTAGAGCAAAGAAAGGGTGGATGGATTGAAAAGATTAGCCTCTGTCTCGGTGGCAGGTTCCCACCTCGCAAGCAATTGGAAACA
AAACTTTTGGGGAGTTTTATTTTGCATTAGGGTGTGTTTTATGTTAAGCAAAACATACTTTAGAAACAAATGAAAAAGGCAATTGAAAAT
CCCAGCTATTTCACCTAGATGGAATAGCCACCCTGAGCAGAACTTTGTGATGCTTCATTCTGTGGAATTTTGTGCTTGCTACTGTATAGT
GCATGTGGTGTAGGTTACTCTAACTGGTTTTGTCGACGTAAACATTTAAAGTGTTATATTTTTTATAAAAATGTTTATTTTTAATGATAT
GAGAAAAATTTTGTTAGGCCACAAAAACACTGCACTGTGAACATTTTAGAAAAGGTATGTCAGACTGGGATTAATGACAGCATGATTTTC
AATGACTGTAAATTGCGATAAGGAAATGTACTGATTGCCAATACACCCCACCCTCATTACATCATCAGGACTTGAAGCCAAGGGTTAACC
CAGCAAGCTACAAAGAGGGTGTGTCACACTGAAACTCAATAGTTGAGTTTGGCTGTTGTTGCAGGAAAATGATTATAACTAAAAGCTCTC
TGATAGTGCAGAGACTTACCAGAAGACACAAGGAATTGTACTGAAGAGCTATTACAATCCAAATATTGCCGTTTCATAAATGTAATAAGT
AATACTAATTCACAGAGTATTGTAAATGGTGGATGACAAAAGAAAATCTGCTCTGTGGAAAGAAAGAACTGTCTCTACCAGGGTCAAGAG
CATGAACGCATCAATAGAAAGAACTCGGGGAAACATCCCATCAACAGGACTACACACTTGTATATACATTCTTGAGAACACTGCAATGTG
AAAATCACGTTTGCTATTTATAAACTTGTCCTTAGATTAATGTGTCTGGACAGATTGTGGGAGTAAGTGATTCTTCTAAGAATTAGATAC
TTGTCACTGCCTATACCTGCAGCTGAACTGAATGGTACTTCGTATGTTAATAGTTGTTCTGATAAATCATGCAATTAAAGTAAAGTGATG

>12985_12985_6_CAPZA2-MET_CAPZA2_chr7_116528244_ENST00000490693_MET_chr7_116414935_ENST00000397752_length(amino acids)=415AA_BP=34
MADLEEQLSDEEKVRIAAKFIIHAPPGEFNEVFNDQFPNSSQNGSCRQVQYPLTDMSPILTSGDSDISSPLLQNTVHIDLSALNPELVQA
VQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLV
VLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKL
PVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVS

--------------------------------------------------------------
>12985_12985_7_CAPZA2-MET_CAPZA2_chr7_116550365_ENST00000361183_MET_chr7_116409699_ENST00000318493_length(transcript)=2532nt_BP=724nt
CCCGGGGTGCGCGTGCGCGGCGGCCTGAGCGGCGGGCCCCTCCCTTAGCGGGGGCGCGCGGCGCTGAGGACCGCACGGAAACGGGGAAGT
CAGGTGGCCGCTGCCGCCGCCGCCGCCGCGGTTTGTCGCCAGAAGGAAGATGGCGGATCTGGAGGAGCAGTTGTCTGATGAAGAGAAGGT
GCGTATAGCAGCAAAATTCATCATTCATGCCCCTCCTGGAGAATTTAATGAGGTTTTCAATGATGTTCGGTTACTGCTTAATAATGACAA
TCTTCTCAGGGAAGGAGCAGCCCATGCATTTGCACAGTATAACTTGGACCAGTTTACTCCAGTAAAAATTGAAGGTTATGAAGATCAGGT
ATTGATAACAGAACATGGCGACTTGGGAAATGGAAAGTTTTTGGATCCAAAGAACAGAATCTGTTTTAAATTTGATCACTTAAGGAAGGA
GGCAACTGATCCAAGACCCTGTGAAGTAGAAAATGCAGTTGAATCATGGAGAACTTCAGTAGAAACTGCTCTGAGAGCTTACGTAAAAGA
ACATTACCCGAATGGAGTCTGCACTGTGTATGGCAAAAAAATAGATGGACAGCAAACCATTATTGCATGCATAGAAAGCCATCAGTTCCA
AGCAAAAAATTTTTGGAATGGTCGTTGGAGGTCAGAATGGAAGTTTACAATCACTCCTTCAACCACTCAAGTGGTTGGCATCTTGAAAAT
TCAGGGAAATGATATTGACCCTGAAGCAGTTAAAGGTGAAGTGTTAAAAGTTGGAAATAAGAGCTGTGAGAATATACACTTACATTCTGA
AGCCGTTTTATGCACGGTCCCCAATGACCTGCTGAAATTGAACAGCGAGCTAAATATAGAGTGGAAGCAAGCAATTTCTTCAACCGTCCT
TGGAAAAGTAATAGTTCAACCAGATCAGAATTTCACAGGATTGATTGCTGGTGTTGTCTCAATATCAACAGCACTGTTATTACTACTTGG
GTTTTTCCTGTGGCTGAAAAAGAGAAAGCAAATTAAAGATCTGGGCAGTGAATTAGTTCGCTACGATGCAAGAGTACACACTCCTCATTT
GGATAGGCTTGTAAGTGCCCGAAGTGTAAGCCCAACTACAGAAATGGTTTCAAATGAATCTGTAGACTACCGAGCTACTTTTCCAGAAGA
TCAGTTTCCTAATTCATCTCAGAACGGTTCATGCCGACAAGTGCAGTATCCTCTGACAGACATGTCCCCCATCCTAACTAGTGGGGACTC
TGATATATCCAGTCCATTACTGCAAAATACTGTCCACATTGACCTCAGTGCTCTAAATCCAGAGCTGGTCCAGGCAGTGCAGCATGTAGT
GATTGGGCCCAGTAGCCTGATTGTGCATTTCAATGAAGTCATAGGAAGAGGGCATTTTGGTTGTGTATATCATGGGACTTTGTTGGACAA
TGATGGCAAGAAAATTCACTGTGCTGTGAAATCCTTGAACAGAATCACTGACATAGGAGAAGTTTCCCAATTTCTGACCGAGGGAATCAT
CATGAAAGATTTTAGTCATCCCAATGTCCTCTCGCTCCTGGGAATCTGCCTGCGAAGTGAAGGGTCTCCGCTGGTGGTCCTACCATACAT
GAAACATGGAGATCTTCGAAATTTCATTCGAAATGAGACTCATAATCCAACTGTAAAAGATCTTATTGGCTTTGGTCTTCAAGTAGCCAA
AGGCATGAAATATCTTGCAAGCAAAAAGTTTGTCCACAGAGACTTGGCTGCAAGAAACTGTATGCTGGATGAAAAATTCACAGTCAAGGT
TGCTGATTTTGGTCTTGCCAGAGACATGTATGATAAAGAATACTATAGTGTACACAACAAAACAGGTGCAAAGCTGCCAGTGAAGTGGAT
GGCTTTGGAAAGTCTGCAAACTCAAAAGTTTACCACCAAGTCAGATGTGTGGTCCTTTGGCGTGCTCCTCTGGGAGCTGATGACAAGAGG
AGCCCCACCTTATCCTGACGTAAACACCTTTGATATAACTGTTTACTTGTTGCAAGGGAGAAGACTCCTACAACCCGAATACTGCCCAGA
CCCCTTATATGAAGTAATGCTAAAATGCTGGCACCCTAAAGCCGAAATGCGCCCATCCTTTTCTGAACTGGTGTCCCGGATATCAGCGAT
CTTCTCTACTTTCATTGGGGAGCACTATGTCCATGTGAACGCTACTTATGTGAACGTAAAATGTGTCGCTCCGTATCCTTCTCTGTTGTC
ATCAGAAGATAACGCTGATGATGAGGTGGACACACGACCAGCCTCCTTCTGGGAGACATCATAGTGCTAGTACTATGTCAAAGCAACAGT
CCACACTTTGTCCAATGGTTTTTTCACTGCCTGACCTTTAAAAGGCCATCGATATTCTTTGCTCTTGCCAAAATTGCACTATTATAGGAC
TTGTATTGTTATTTAAATTACTGGATTCTAAGGAATTTCTTATCTGACAGAGCATCAGAACCAGAGGCTTGGTCCCACAGGCCACGGACC

>12985_12985_7_CAPZA2-MET_CAPZA2_chr7_116550365_ENST00000361183_MET_chr7_116409699_ENST00000318493_length(amino acids)=737AA_BP=207
MPPPPPRFVARRKMADLEEQLSDEEKVRIAAKFIIHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNLDQFTPVKIEGYEDQVLIT
EHGDLGNGKFLDPKNRICFKFDHLRKEATDPRPCEVENAVESWRTSVETALRAYVKEHYPNGVCTVYGKKIDGQQTIIACIESHQFQAKN
FWNGRWRSEWKFTITPSTTQVVGILKIQGNDIDPEAVKGEVLKVGNKSCENIHLHSEAVLCTVPNDLLKLNSELNIEWKQAISSTVLGKV
IVQPDQNFTGLIAGVVSISTALLLLLGFFLWLKKRKQIKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEMVSNESVDYRATFPEDQFP
NSSQNGSCRQVQYPLTDMSPILTSGDSDISSPLLQNTVHIDLSALNPELVQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGK
KIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMK
YLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPP
YPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHYVHVNATYVNVKCVAPYPSLLSSED

--------------------------------------------------------------
>12985_12985_8_CAPZA2-MET_CAPZA2_chr7_116550365_ENST00000361183_MET_chr7_116409699_ENST00000397752_length(transcript)=4576nt_BP=724nt
CCCGGGGTGCGCGTGCGCGGCGGCCTGAGCGGCGGGCCCCTCCCTTAGCGGGGGCGCGCGGCGCTGAGGACCGCACGGAAACGGGGAAGT
CAGGTGGCCGCTGCCGCCGCCGCCGCCGCGGTTTGTCGCCAGAAGGAAGATGGCGGATCTGGAGGAGCAGTTGTCTGATGAAGAGAAGGT
GCGTATAGCAGCAAAATTCATCATTCATGCCCCTCCTGGAGAATTTAATGAGGTTTTCAATGATGTTCGGTTACTGCTTAATAATGACAA
TCTTCTCAGGGAAGGAGCAGCCCATGCATTTGCACAGTATAACTTGGACCAGTTTACTCCAGTAAAAATTGAAGGTTATGAAGATCAGGT
ATTGATAACAGAACATGGCGACTTGGGAAATGGAAAGTTTTTGGATCCAAAGAACAGAATCTGTTTTAAATTTGATCACTTAAGGAAGGA
GGCAACTGATCCAAGACCCTGTGAAGTAGAAAATGCAGTTGAATCATGGAGAACTTCAGTAGAAACTGCTCTGAGAGCTTACGTAAAAGA
ACATTACCCGAATGGAGTCTGCACTGTGTATGGCAAAAAAATAGATGGACAGCAAACCATTATTGCATGCATAGAAAGCCATCAGTTCCA
AGCAAAAAATTTTTGGAATGGTCGTTGGAGGTCAGAATGGAAGTTTACAATCACTCCTTCAACCACTCAAGTGGTTGGCATCTTGAAAAT
TCAGGGAAATGATATTGACCCTGAAGCAGTTAAAGGTGAAGTGTTAAAAGTTGGAAATAAGAGCTGTGAGAATATACACTTACATTCTGA
AGCCGTTTTATGCACGGTCCCCAATGACCTGCTGAAATTGAACAGCGAGCTAAATATAGAGTGGAAGCAAGCAATTTCTTCAACCGTCCT
TGGAAAAGTAATAGTTCAACCAGATCAGAATTTCACAGGATTGATTGCTGGTGTTGTCTCAATATCAACAGCACTGTTATTACTACTTGG
GTTTTTCCTGTGGCTGAAAAAGAGAAAGCAAATTAAAGATCTGGGCAGTGAATTAGTTCGCTACGATGCAAGAGTACACACTCCTCATTT
GGATAGGCTTGTAAGTGCCCGAAGTGTAAGCCCAACTACAGAAATGGTTTCAAATGAATCTGTAGACTACCGAGCTACTTTTCCAGAAGA
TCAGTTTCCTAATTCATCTCAGAACGGTTCATGCCGACAAGTGCAGTATCCTCTGACAGACATGTCCCCCATCCTAACTAGTGGGGACTC
TGATATATCCAGTCCATTACTGCAAAATACTGTCCACATTGACCTCAGTGCTCTAAATCCAGAGCTGGTCCAGGCAGTGCAGCATGTAGT
GATTGGGCCCAGTAGCCTGATTGTGCATTTCAATGAAGTCATAGGAAGAGGGCATTTTGGTTGTGTATATCATGGGACTTTGTTGGACAA
TGATGGCAAGAAAATTCACTGTGCTGTGAAATCCTTGAACAGAATCACTGACATAGGAGAAGTTTCCCAATTTCTGACCGAGGGAATCAT
CATGAAAGATTTTAGTCATCCCAATGTCCTCTCGCTCCTGGGAATCTGCCTGCGAAGTGAAGGGTCTCCGCTGGTGGTCCTACCATACAT
GAAACATGGAGATCTTCGAAATTTCATTCGAAATGAGACTCATAATCCAACTGTAAAAGATCTTATTGGCTTTGGTCTTCAAGTAGCCAA
AGGCATGAAATATCTTGCAAGCAAAAAGTTTGTCCACAGAGACTTGGCTGCAAGAAACTGTATGCTGGATGAAAAATTCACAGTCAAGGT
TGCTGATTTTGGTCTTGCCAGAGACATGTATGATAAAGAATACTATAGTGTACACAACAAAACAGGTGCAAAGCTGCCAGTGAAGTGGAT
GGCTTTGGAAAGTCTGCAAACTCAAAAGTTTACCACCAAGTCAGATGTGTGGTCCTTTGGCGTGCTCCTCTGGGAGCTGATGACAAGAGG
AGCCCCACCTTATCCTGACGTAAACACCTTTGATATAACTGTTTACTTGTTGCAAGGGAGAAGACTCCTACAACCCGAATACTGCCCAGA
CCCCTTATATGAAGTAATGCTAAAATGCTGGCACCCTAAAGCCGAAATGCGCCCATCCTTTTCTGAACTGGTGTCCCGGATATCAGCGAT
CTTCTCTACTTTCATTGGGGAGCACTATGTCCATGTGAACGCTACTTATGTGAACGTAAAATGTGTCGCTCCGTATCCTTCTCTGTTGTC
ATCAGAAGATAACGCTGATGATGAGGTGGACACACGACCAGCCTCCTTCTGGGAGACATCATAGTGCTAGTACTATGTCAAAGCAACAGT
CCACACTTTGTCCAATGGTTTTTTCACTGCCTGACCTTTAAAAGGCCATCGATATTCTTTGCTCTTGCCAAAATTGCACTATTATAGGAC
TTGTATTGTTATTTAAATTACTGGATTCTAAGGAATTTCTTATCTGACAGAGCATCAGAACCAGAGGCTTGGTCCCACAGGCCACGGACC
AATGGCCTGCAGCCGTGACAACACTCCTGTCATATTGGAGTCCAAAACTTGAATTCTGGGTTGAATTTTTTAAAAATCAGGTACCACTTG
ATTTCATATGGGAAATTGAAGCAGGAAATATTGAGGGCTTCTTGATCACAGAAAACTCAGAAGAGATAGTAATGCTCAGGACAGGAGCGG
CAGCCCCAGAACAGGCCACTCATTTAGAATTCTAGTGTTTCAAAACACTTTTGTGTGTTGTATGGTCAATAACATTTTTCATTACTGATG
GTGTCATTCACCCATTAGGTAAACATTCCCTTTTAAATGTTTGTTTGTTTTTTGAGACAGGATCTCACTCTGTTGCCAGGGCTGTAGTGC
AGTGGTGTGATCATAGCTCACTGCAACCTCCACCTCCCAGGCTCAAGCCTCCCGAATAGCTGGGACTACAGGCGCACACCACCATCCCCG
GCTAATTTTTGTATTTTTTGTAGAGACGGGGTTTTGCCATGTTGCCAAGGCTGGTTTCAAACTCCTGGACTCAAGAAATCCACCCACCTC
AGCCTCCCAAAGTGCTAGGATTACAGGCATGAGCCACTGCGCCCAGCCCTTATAAATTTTTGTATAGACATTCCTTTGGTTGGAAGAATA
TTTATAGGCAATACAGTCAAAGTTTCAAAATAGCATCACACAAAACATGTTTATAAATGAACAGGATGTAATGTACATAGATGACATTAA
GAAAATTTGTATGAAATAATTTAGTCATCATGAAATATTTAGTTGTCATATAAAAACCCACTGTTTGAGAATGATGCTACTCTGATCTAA
TGAATGTGAACATGTAGATGTTTTGTGTGTATTTTTTTAAATGAAAACTCAAAATAAGACAAGTAATTTGTTGATAAATATTTTTAAAGA
TAACTCAGCATGTTTGTAAAGCAGGATACATTTTACTAAAAGGTTCATTGGTTCCAATCACAGCTCATAGGTAGAGCAAAGAAAGGGTGG
ATGGATTGAAAAGATTAGCCTCTGTCTCGGTGGCAGGTTCCCACCTCGCAAGCAATTGGAAACAAAACTTTTGGGGAGTTTTATTTTGCA
TTAGGGTGTGTTTTATGTTAAGCAAAACATACTTTAGAAACAAATGAAAAAGGCAATTGAAAATCCCAGCTATTTCACCTAGATGGAATA
GCCACCCTGAGCAGAACTTTGTGATGCTTCATTCTGTGGAATTTTGTGCTTGCTACTGTATAGTGCATGTGGTGTAGGTTACTCTAACTG
GTTTTGTCGACGTAAACATTTAAAGTGTTATATTTTTTATAAAAATGTTTATTTTTAATGATATGAGAAAAATTTTGTTAGGCCACAAAA
ACACTGCACTGTGAACATTTTAGAAAAGGTATGTCAGACTGGGATTAATGACAGCATGATTTTCAATGACTGTAAATTGCGATAAGGAAA
TGTACTGATTGCCAATACACCCCACCCTCATTACATCATCAGGACTTGAAGCCAAGGGTTAACCCAGCAAGCTACAAAGAGGGTGTGTCA
CACTGAAACTCAATAGTTGAGTTTGGCTGTTGTTGCAGGAAAATGATTATAACTAAAAGCTCTCTGATAGTGCAGAGACTTACCAGAAGA
CACAAGGAATTGTACTGAAGAGCTATTACAATCCAAATATTGCCGTTTCATAAATGTAATAAGTAATACTAATTCACAGAGTATTGTAAA
TGGTGGATGACAAAAGAAAATCTGCTCTGTGGAAAGAAAGAACTGTCTCTACCAGGGTCAAGAGCATGAACGCATCAATAGAAAGAACTC
GGGGAAACATCCCATCAACAGGACTACACACTTGTATATACATTCTTGAGAACACTGCAATGTGAAAATCACGTTTGCTATTTATAAACT
TGTCCTTAGATTAATGTGTCTGGACAGATTGTGGGAGTAAGTGATTCTTCTAAGAATTAGATACTTGTCACTGCCTATACCTGCAGCTGA

>12985_12985_8_CAPZA2-MET_CAPZA2_chr7_116550365_ENST00000361183_MET_chr7_116409699_ENST00000397752_length(amino acids)=737AA_BP=207
MPPPPPRFVARRKMADLEEQLSDEEKVRIAAKFIIHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNLDQFTPVKIEGYEDQVLIT
EHGDLGNGKFLDPKNRICFKFDHLRKEATDPRPCEVENAVESWRTSVETALRAYVKEHYPNGVCTVYGKKIDGQQTIIACIESHQFQAKN
FWNGRWRSEWKFTITPSTTQVVGILKIQGNDIDPEAVKGEVLKVGNKSCENIHLHSEAVLCTVPNDLLKLNSELNIEWKQAISSTVLGKV
IVQPDQNFTGLIAGVVSISTALLLLLGFFLWLKKRKQIKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEMVSNESVDYRATFPEDQFP
NSSQNGSCRQVQYPLTDMSPILTSGDSDISSPLLQNTVHIDLSALNPELVQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGK
KIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMK
YLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPP
YPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHYVHVNATYVNVKCVAPYPSLLSSED

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Fusion Gene PPI Analysis for CAPZA2-MET


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneMETchr7:116502704chr7:116435709ENST0000031849318211320_13591284.01409.0MUC20
TgeneMETchr7:116502704chr7:116435709ENST0000039775218211320_13591266.01391.0MUC20
TgeneMETchr7:116502704chr7:116435709ENST00000436117091320_13590.0765.0MUC20
TgeneMETchr7:116528244chr7:116414935ENST0000031849313211320_13591027.33333333333331409.0MUC20
TgeneMETchr7:116528244chr7:116414935ENST0000039775213211320_13591009.33333333333341391.0MUC20
TgeneMETchr7:116528244chr7:116414935ENST00000436117091320_13590.0765.0MUC20
TgeneMETchr7:116550365chr7:116409699ENST0000031849310211320_1359879.01409.0MUC20
TgeneMETchr7:116550365chr7:116409699ENST0000039775210211320_1359861.01391.0MUC20
TgeneMETchr7:116550365chr7:116409699ENST00000436117091320_13590.0765.0MUC20
TgeneMETchr7:116502704chr7:116435709ENST00000436117091212_13900.0765.0RANBP9
TgeneMETchr7:116528244chr7:116414935ENST0000031849313211212_13901027.33333333333331409.0RANBP9
TgeneMETchr7:116528244chr7:116414935ENST0000039775213211212_13901009.33333333333341391.0RANBP9
TgeneMETchr7:116528244chr7:116414935ENST00000436117091212_13900.0765.0RANBP9
TgeneMETchr7:116550365chr7:116409699ENST0000031849310211212_1390879.01409.0RANBP9
TgeneMETchr7:116550365chr7:116409699ENST0000039775210211212_1390861.01391.0RANBP9
TgeneMETchr7:116550365chr7:116409699ENST00000436117091212_13900.0765.0RANBP9


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
TgeneMETchr7:116502704chr7:116435709ENST0000031849318211212_13901284.01409.0RANBP9
TgeneMETchr7:116502704chr7:116435709ENST0000039775218211212_13901266.01391.0RANBP9


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CAPZA2-MET


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status
TgeneMETP08581DB08865CrizotinibInhibitorSmall moleculeApproved
TgeneMETP08581DB08875CabozantinibAntagonistSmall moleculeApproved|Investigational
TgeneMETP08581DB11791CapmatinibInhibitorSmall moleculeApproved|Investigational
TgeneMETP08581DB12010FostamatinibInhibitorSmall moleculeApproved|Investigational
TgeneMETP08581DB12267BrigatinibInhibitorSmall moleculeApproved|Investigational

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Related Diseases for CAPZA2-MET


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneC1306837Papillary Renal Cell Carcinoma9CGI;CLINGEN;CTD_human;ORPHANET
TgeneC1336078Papillary renal cell carcinoma, sporadic7CLINGEN
TgeneC1336839Type 1 Papillary Renal Cell Carcinoma5UNIPROT
TgeneC0007131Non-Small Cell Lung Carcinoma4CGI;CTD_human
TgeneC1836723Tibia, Bowing of, with Pseudarthrosis and Pectus Excavatum4ORPHANET
TgeneC4085248OSTEOFIBROUS DYSPLASIA, SUSCEPTIBILITY TO4ORPHANET
TgeneC0001418Adenocarcinoma2CTD_human
TgeneC0004352Autistic Disorder2CTD_human
TgeneC0024623Malignant neoplasm of stomach2CGI;CTD_human;UNIPROT
TgeneC0027627Neoplasm Metastasis2CTD_human
TgeneC0038356Stomach Neoplasms2CGI;CTD_human
TgeneC0205641Adenocarcinoma, Basal Cell2CTD_human
TgeneC0205642Adenocarcinoma, Oxyphilic2CTD_human
TgeneC0205643Carcinoma, Cribriform2CTD_human
TgeneC0205644Carcinoma, Granular Cell2CTD_human
TgeneC0205645Adenocarcinoma, Tubular2CTD_human
TgeneC1708349Hereditary Diffuse Gastric Cancer2CTD_human
TgeneC0004114Astrocytoma1CTD_human
TgeneC0007097Carcinoma1CTD_human
TgeneC0007134Renal Cell Carcinoma1CTD_human
TgeneC0007137Squamous cell carcinoma1CTD_human
TgeneC0009241Cognition Disorders1CTD_human
TgeneC0014859Esophageal Neoplasms1CTD_human
TgeneC0017636Glioblastoma1CTD_human
TgeneC0019189Hepatitis, Chronic1CTD_human
TgeneC0019207Hepatoma, Morris1CTD_human
TgeneC0019208Hepatoma, Novikoff1CTD_human
TgeneC0023467Leukemia, Myelocytic, Acute1CTD_human
TgeneC0023904Liver Neoplasms, Experimental1CTD_human
TgeneC0024121Lung Neoplasms1CTD_human
TgeneC0024232Lymphatic Metastasis1CTD_human
TgeneC0025202melanoma1CTD_human
TgeneC0026998Acute Myeloid Leukemia, M11CTD_human
TgeneC0027626Neoplasm Invasiveness1CTD_human
TgeneC0027819Neuroblastoma1CTD_human
TgeneC0029463Osteosarcoma1CTD_human
TgeneC0033578Prostatic Neoplasms1CTD_human
TgeneC0036341Schizophrenia1CTD_human
TgeneC0037199Sinusitis1CTD_human
TgeneC0086404Experimental Hepatoma1CTD_human
TgeneC0149519Chronic Persistent Hepatitis1CTD_human
TgeneC0205696Anaplastic carcinoma1CTD_human
TgeneC0205697Carcinoma, Spindle-Cell1CTD_human
TgeneC0205698Undifferentiated carcinoma1CTD_human
TgeneC0205699Carcinomatosis1CTD_human
TgeneC0205768Subependymal Giant Cell Astrocytoma1CTD_human
TgeneC0242379Malignant neoplasm of lung1CTD_human
TgeneC0279606Childhood Hepatocellular Carcinoma1ORPHANET
TgeneC0279702Conventional (Clear Cell) Renal Cell Carcinoma1CGI;CTD_human
TgeneC0280783Juvenile Pilocytic Astrocytoma1CTD_human
TgeneC0280785Diffuse Astrocytoma1CTD_human
TgeneC0334579Anaplastic astrocytoma1CTD_human
TgeneC0334580Protoplasmic astrocytoma1CTD_human
TgeneC0334581Gemistocytic astrocytoma1CTD_human
TgeneC0334582Fibrillary Astrocytoma1CTD_human
TgeneC0334583Pilocytic Astrocytoma1CTD_human
TgeneC0334588Giant Cell Glioblastoma1CTD_human
TgeneC0338070Childhood Cerebral Astrocytoma1CTD_human
TgeneC0345967Malignant mesothelioma1CTD_human
TgeneC0376358Malignant neoplasm of prostate1CTD_human
TgeneC0520463Chronic active hepatitis1CTD_human
TgeneC0524611Cryptogenic Chronic Hepatitis1CTD_human
TgeneC0546837Malignant neoplasm of esophagus1CTD_human
TgeneC0547065Mixed oligoastrocytoma1CTD_human
TgeneC0750935Cerebral Astrocytoma1CTD_human
TgeneC0750936Intracranial Astrocytoma1CTD_human
TgeneC0919267ovarian neoplasm1CTD_human
TgeneC1140680Malignant neoplasm of ovary1CTD_human
TgeneC1266042Chromophobe Renal Cell Carcinoma1CTD_human
TgeneC1266043Sarcomatoid Renal Cell Carcinoma1CTD_human
TgeneC1266044Collecting Duct Carcinoma of the Kidney1CTD_human
TgeneC1621958Glioblastoma Multiforme1CTD_human
TgeneC1704230Grade I Astrocytoma1CTD_human
TgeneC1708353Hereditary Paraganglioma-Pheochromocytoma Syndrome1CLINGEN
TgeneC1876165Copper-Overload Cirrhosis1CTD_human
TgeneC1879321Acute Myeloid Leukemia (AML-M2)1CTD_human
TgeneC2239176Liver carcinoma1CGI;CTD_human;UNIPROT
TgeneC3711374Nonsyndromic Deafness1CLINGEN
TgeneC4084709DEAFNESS, AUTOSOMAL RECESSIVE 971CTD_human;UNIPROT