Fusion Gene Studies
in Kim Lab

FusionBase FusionGDB FusionGDB2 FusionPDB FusionNeoAntigen FusionAI FusionNW FGviewer Publication Contact
FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:BRAP-ATXN2 (FusionGDB2 ID:HG8315TG6311)

Fusion Gene Summary for BRAP-ATXN2

check button Fusion gene summary
Fusion gene informationFusion gene name: BRAP-ATXN2
Fusion gene ID: hg8315tg6311
HgeneTgene
Gene symbol

BRAP

ATXN2

Gene ID

8315

6311

Gene nameBRCA1 associated proteinataxin 2
SynonymsBRAP2|IMP|RNF52ATX2|SCA2|TNRC13
Cytomap('BRAP')('ATXN2')

12q24.12

12q24.12

Type of geneprotein-codingprotein-coding
DescriptionBRCA1-associated proteinRING finger protein 52RING-type E3 ubiquitin transferase BRAP2galectin-2-binding proteinimpedes mitogenic signal propagationrenal carcinoma antigen NY-REN-63ataxin-2spinocerebellar ataxia type 2 proteintrinucleotide repeat-containing gene 13 protein
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000327551, ENST00000419234, 
ENST00000539060, 		ENST00000327551, 
ENST00000419234, ENST00000539060, 
Fusion gene scores* DoF score6 X 11 X 6=39621 X 19 X 10=3990
# samples 1027
** MAII scorelog2(10/396*10)=-1.98550043030488
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(27/3990*10)=-3.88535743405888
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: BRAP [Title/Abstract] AND ATXN2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointBRAP(112110465)-ATXN2(111902519), # samples:1
BRAP(112120950)-ATXN2(111895163), # samples:1
BRAP(112120950)-ATXN2(111902519), # samples:1
BRAP(112096540)-ATXN2(111908546), # samples:1
Anticipated loss of major functional domain due to fusion event.ATXN2-BRAP seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ATXN2-BRAP seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
BRAP-ATXN2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
BRAP-ATXN2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
ATXN2-BRAP seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
BRAP-ATXN2 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneBRAP

GO:0000165

MAPK cascade

14724641

HgeneBRAP

GO:0007265

Ras protein signal transduction

14724641

HgeneBRAP

GO:0009968

negative regulation of signal transduction

14724641

HgeneBRAP

GO:0016567

protein ubiquitination

14724641


check buttonFusion gene breakpoints across BRAP (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across ATXN2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LIHCTCGA-BC-4073-01BBRAPchr12

112110465

-ATXN2chr12

111902519

-
ChimerDB4STADTCGA-HU-A4HB-01ABRAPchr12

112096540

-ATXN2chr12

111908546

-
ChimerDB4STADTCGA-VQ-A8P3-01ABRAPchr12

112120950

-ATXN2chr12

111895163

-
ChimerDB4STADTCGA-VQ-A8P3-01ABRAPchr12

112120950

-ATXN2chr12

111902519

-


Top

Fusion Gene ORF analysis for BRAP-ATXN2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000327551ENST00000535949BRAPchr12

112120950

-ATXN2chr12

111895163

-
5CDS-3UTRENST00000327551ENST00000542287BRAPchr12

112110465

-ATXN2chr12

111902519

-
5CDS-3UTRENST00000327551ENST00000542287BRAPchr12

112120950

-ATXN2chr12

111895163

-
5CDS-3UTRENST00000327551ENST00000542287BRAPchr12

112120950

-ATXN2chr12

111902519

-
5CDS-3UTRENST00000327551ENST00000550104BRAPchr12

112110465

-ATXN2chr12

111902519

-
5CDS-3UTRENST00000327551ENST00000550104BRAPchr12

112120950

-ATXN2chr12

111895163

-
5CDS-3UTRENST00000327551ENST00000550104BRAPchr12

112120950

-ATXN2chr12

111902519

-
5CDS-3UTRENST00000419234ENST00000535949BRAPchr12

112120950

-ATXN2chr12

111895163

-
5CDS-3UTRENST00000419234ENST00000542287BRAPchr12

112110465

-ATXN2chr12

111902519

-
5CDS-3UTRENST00000419234ENST00000542287BRAPchr12

112120950

-ATXN2chr12

111895163

-
5CDS-3UTRENST00000419234ENST00000542287BRAPchr12

112120950

-ATXN2chr12

111902519

-
5CDS-3UTRENST00000419234ENST00000550104BRAPchr12

112110465

-ATXN2chr12

111902519

-
5CDS-3UTRENST00000419234ENST00000550104BRAPchr12

112120950

-ATXN2chr12

111895163

-
5CDS-3UTRENST00000419234ENST00000550104BRAPchr12

112120950

-ATXN2chr12

111902519

-
5CDS-intronENST00000327551ENST00000535949BRAPchr12

112110465

-ATXN2chr12

111902519

-
5CDS-intronENST00000327551ENST00000535949BRAPchr12

112120950

-ATXN2chr12

111902519

-
5CDS-intronENST00000327551ENST00000549455BRAPchr12

112110465

-ATXN2chr12

111902519

-
5CDS-intronENST00000327551ENST00000549455BRAPchr12

112096540

-ATXN2chr12

111908546

-
5CDS-intronENST00000327551ENST00000549455BRAPchr12

112120950

-ATXN2chr12

111895163

-
5CDS-intronENST00000327551ENST00000549455BRAPchr12

112120950

-ATXN2chr12

111902519

-
5CDS-intronENST00000419234ENST00000535949BRAPchr12

112110465

-ATXN2chr12

111902519

-
5CDS-intronENST00000419234ENST00000535949BRAPchr12

112120950

-ATXN2chr12

111902519

-
5CDS-intronENST00000419234ENST00000549455BRAPchr12

112110465

-ATXN2chr12

111902519

-
5CDS-intronENST00000419234ENST00000549455BRAPchr12

112096540

-ATXN2chr12

111908546

-
5CDS-intronENST00000419234ENST00000549455BRAPchr12

112120950

-ATXN2chr12

111895163

-
5CDS-intronENST00000419234ENST00000549455BRAPchr12

112120950

-ATXN2chr12

111902519

-
5CDS-intronENST00000539060ENST00000549455BRAPchr12

112096540

-ATXN2chr12

111908546

-
Frame-shiftENST00000327551ENST00000377617BRAPchr12

112110465

-ATXN2chr12

111902519

-
Frame-shiftENST00000327551ENST00000377617BRAPchr12

112096540

-ATXN2chr12

111908546

-
Frame-shiftENST00000327551ENST00000389153BRAPchr12

112110465

-ATXN2chr12

111902519

-
Frame-shiftENST00000327551ENST00000389153BRAPchr12

112096540

-ATXN2chr12

111908546

-
Frame-shiftENST00000327551ENST00000535949BRAPchr12

112096540

-ATXN2chr12

111908546

-
Frame-shiftENST00000327551ENST00000542287BRAPchr12

112096540

-ATXN2chr12

111908546

-
Frame-shiftENST00000327551ENST00000550104BRAPchr12

112096540

-ATXN2chr12

111908546

-
Frame-shiftENST00000327551ENST00000608853BRAPchr12

112110465

-ATXN2chr12

111902519

-
Frame-shiftENST00000327551ENST00000608853BRAPchr12

112096540

-ATXN2chr12

111908546

-
Frame-shiftENST00000419234ENST00000377617BRAPchr12

112110465

-ATXN2chr12

111902519

-
Frame-shiftENST00000419234ENST00000377617BRAPchr12

112096540

-ATXN2chr12

111908546

-
Frame-shiftENST00000419234ENST00000389153BRAPchr12

112110465

-ATXN2chr12

111902519

-
Frame-shiftENST00000419234ENST00000389153BRAPchr12

112096540

-ATXN2chr12

111908546

-
Frame-shiftENST00000419234ENST00000535949BRAPchr12

112096540

-ATXN2chr12

111908546

-
Frame-shiftENST00000419234ENST00000542287BRAPchr12

112096540

-ATXN2chr12

111908546

-
Frame-shiftENST00000419234ENST00000550104BRAPchr12

112096540

-ATXN2chr12

111908546

-
Frame-shiftENST00000419234ENST00000608853BRAPchr12

112110465

-ATXN2chr12

111902519

-
Frame-shiftENST00000419234ENST00000608853BRAPchr12

112096540

-ATXN2chr12

111908546

-
Frame-shiftENST00000539060ENST00000377617BRAPchr12

112096540

-ATXN2chr12

111908546

-
Frame-shiftENST00000539060ENST00000389153BRAPchr12

112096540

-ATXN2chr12

111908546

-
Frame-shiftENST00000539060ENST00000535949BRAPchr12

112096540

-ATXN2chr12

111908546

-
Frame-shiftENST00000539060ENST00000542287BRAPchr12

112096540

-ATXN2chr12

111908546

-
Frame-shiftENST00000539060ENST00000550104BRAPchr12

112096540

-ATXN2chr12

111908546

-
Frame-shiftENST00000539060ENST00000608853BRAPchr12

112096540

-ATXN2chr12

111908546

-
In-frameENST00000327551ENST00000377617BRAPchr12

112120950

-ATXN2chr12

111895163

-
In-frameENST00000327551ENST00000377617BRAPchr12

112120950

-ATXN2chr12

111902519

-
In-frameENST00000327551ENST00000389153BRAPchr12

112120950

-ATXN2chr12

111895163

-
In-frameENST00000327551ENST00000389153BRAPchr12

112120950

-ATXN2chr12

111902519

-
In-frameENST00000327551ENST00000608853BRAPchr12

112120950

-ATXN2chr12

111895163

-
In-frameENST00000327551ENST00000608853BRAPchr12

112120950

-ATXN2chr12

111902519

-
In-frameENST00000419234ENST00000377617BRAPchr12

112120950

-ATXN2chr12

111895163

-
In-frameENST00000419234ENST00000377617BRAPchr12

112120950

-ATXN2chr12

111902519

-
In-frameENST00000419234ENST00000389153BRAPchr12

112120950

-ATXN2chr12

111895163

-
In-frameENST00000419234ENST00000389153BRAPchr12

112120950

-ATXN2chr12

111902519

-
In-frameENST00000419234ENST00000608853BRAPchr12

112120950

-ATXN2chr12

111895163

-
In-frameENST00000419234ENST00000608853BRAPchr12

112120950

-ATXN2chr12

111902519

-
intron-3CDSENST00000539060ENST00000377617BRAPchr12

112110465

-ATXN2chr12

111902519

-
intron-3CDSENST00000539060ENST00000377617BRAPchr12

112120950

-ATXN2chr12

111895163

-
intron-3CDSENST00000539060ENST00000377617BRAPchr12

112120950

-ATXN2chr12

111902519

-
intron-3CDSENST00000539060ENST00000389153BRAPchr12

112110465

-ATXN2chr12

111902519

-
intron-3CDSENST00000539060ENST00000389153BRAPchr12

112120950

-ATXN2chr12

111895163

-
intron-3CDSENST00000539060ENST00000389153BRAPchr12

112120950

-ATXN2chr12

111902519

-
intron-3CDSENST00000539060ENST00000608853BRAPchr12

112110465

-ATXN2chr12

111902519

-
intron-3CDSENST00000539060ENST00000608853BRAPchr12

112120950

-ATXN2chr12

111895163

-
intron-3CDSENST00000539060ENST00000608853BRAPchr12

112120950

-ATXN2chr12

111902519

-
intron-3UTRENST00000539060ENST00000535949BRAPchr12

112120950

-ATXN2chr12

111895163

-
intron-3UTRENST00000539060ENST00000542287BRAPchr12

112110465

-ATXN2chr12

111902519

-
intron-3UTRENST00000539060ENST00000542287BRAPchr12

112120950

-ATXN2chr12

111895163

-
intron-3UTRENST00000539060ENST00000542287BRAPchr12

112120950

-ATXN2chr12

111902519

-
intron-3UTRENST00000539060ENST00000550104BRAPchr12

112110465

-ATXN2chr12

111902519

-
intron-3UTRENST00000539060ENST00000550104BRAPchr12

112120950

-ATXN2chr12

111895163

-
intron-3UTRENST00000539060ENST00000550104BRAPchr12

112120950

-ATXN2chr12

111902519

-
intron-intronENST00000539060ENST00000535949BRAPchr12

112110465

-ATXN2chr12

111902519

-
intron-intronENST00000539060ENST00000535949BRAPchr12

112120950

-ATXN2chr12

111902519

-
intron-intronENST00000539060ENST00000549455BRAPchr12

112110465

-ATXN2chr12

111902519

-
intron-intronENST00000539060ENST00000549455BRAPchr12

112120950

-ATXN2chr12

111895163

-
intron-intronENST00000539060ENST00000549455BRAPchr12

112120950

-ATXN2chr12

111902519

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000419234BRAPchr12112120950-ENST00000389153ATXN2chr12111895163-16084381071009300
ENST00000419234BRAPchr12112120950-ENST00000608853ATXN2chr12111895163-16084381071009300
ENST00000419234BRAPchr12112120950-ENST00000377617ATXN2chr12111895163-16084381071009300
ENST00000327551BRAPchr12112120950-ENST00000389153ATXN2chr12111895163-1465295108866252
ENST00000327551BRAPchr12112120950-ENST00000608853ATXN2chr12111895163-1465295108866252
ENST00000327551BRAPchr12112120950-ENST00000377617ATXN2chr12111895163-1465295108866252
ENST00000419234BRAPchr12112120950-ENST00000389153ATXN2chr12111902519-16624381071063318
ENST00000419234BRAPchr12112120950-ENST00000608853ATXN2chr12111902519-16624381071063318
ENST00000419234BRAPchr12112120950-ENST00000377617ATXN2chr12111902519-16624381071063318
ENST00000327551BRAPchr12112120950-ENST00000389153ATXN2chr12111902519-1519295108920270
ENST00000327551BRAPchr12112120950-ENST00000608853ATXN2chr12111902519-1519295108920270
ENST00000327551BRAPchr12112120950-ENST00000377617ATXN2chr12111902519-1519295108920270

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000419234ENST00000389153BRAPchr12112120950-ATXN2chr12111895163-0.0326790060.96732104
ENST00000419234ENST00000608853BRAPchr12112120950-ATXN2chr12111895163-0.0326790060.96732104
ENST00000419234ENST00000377617BRAPchr12112120950-ATXN2chr12111895163-0.0326790060.96732104
ENST00000327551ENST00000389153BRAPchr12112120950-ATXN2chr12111895163-0.032844710.9671553
ENST00000327551ENST00000608853BRAPchr12112120950-ATXN2chr12111895163-0.032844710.9671553
ENST00000327551ENST00000377617BRAPchr12112120950-ATXN2chr12111895163-0.032844710.9671553
ENST00000419234ENST00000389153BRAPchr12112120950-ATXN2chr12111902519-0.0164050720.98359495
ENST00000419234ENST00000608853BRAPchr12112120950-ATXN2chr12111902519-0.0164050720.98359495
ENST00000419234ENST00000377617BRAPchr12112120950-ATXN2chr12111902519-0.0164050720.98359495
ENST00000327551ENST00000389153BRAPchr12112120950-ATXN2chr12111902519-0.0321169760.967883
ENST00000327551ENST00000608853BRAPchr12112120950-ATXN2chr12111902519-0.0321169760.967883
ENST00000327551ENST00000377617BRAPchr12112120950-ATXN2chr12111902519-0.0321169760.967883

Top

Fusion Genomic Features for BRAP-ATXN2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

Top

Fusion Protein Features for BRAP-ATXN2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr12:112110465/chr12:111902519)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneBRAPchr12:112120950chr12:111895163ENST00000419234-212429_53781593.0Coiled coilOntology_term=ECO:0000255
HgeneBRAPchr12:112120950chr12:111902519ENST00000419234-212429_53781593.0Coiled coilOntology_term=ECO:0000255
HgeneBRAPchr12:112120950chr12:111895163ENST00000419234-212264_30481593.0Zinc fingerRING-type
HgeneBRAPchr12:112120950chr12:111895163ENST00000419234-212315_37681593.0Zinc fingerUBP-type
HgeneBRAPchr12:112120950chr12:111902519ENST00000419234-212264_30481593.0Zinc fingerRING-type
HgeneBRAPchr12:112120950chr12:111902519ENST00000419234-212315_37681593.0Zinc fingerUBP-type
TgeneATXN2chr12:112120950chr12:111895163ENST000003776172025166_18711231314.0Compositional biasNote=Poly-Gln
TgeneATXN2chr12:112120950chr12:111895163ENST000003776172025213_22311231314.0Compositional biasNote=Poly-Ser
TgeneATXN2chr12:112120950chr12:111895163ENST00000377617202547_15811231314.0Compositional biasNote=Pro-rich
TgeneATXN2chr12:112120950chr12:111895163ENST000003776172025551_73411231314.0Compositional biasNote=Pro-rich
TgeneATXN2chr12:112120950chr12:111895163ENST00000377617202555_6411231314.0Compositional biasNote=Poly-Pro
TgeneATXN2chr12:112120950chr12:111895163ENST000003776172025929_108511231314.0Compositional biasNote=Pro-rich
TgeneATXN2chr12:112120950chr12:111895163ENST000005501041924166_18711031015.3333333333334Compositional biasNote=Poly-Gln
TgeneATXN2chr12:112120950chr12:111895163ENST000005501041924213_22311031015.3333333333334Compositional biasNote=Poly-Ser
TgeneATXN2chr12:112120950chr12:111895163ENST00000550104192447_15811031015.3333333333334Compositional biasNote=Pro-rich
TgeneATXN2chr12:112120950chr12:111895163ENST000005501041924551_73411031015.3333333333334Compositional biasNote=Pro-rich
TgeneATXN2chr12:112120950chr12:111895163ENST00000550104192455_6411031015.3333333333334Compositional biasNote=Poly-Pro
TgeneATXN2chr12:112120950chr12:111895163ENST000005501041924929_108511031015.3333333333334Compositional biasNote=Pro-rich
TgeneATXN2chr12:112120950chr12:111902519ENST000003776171925166_18711051314.0Compositional biasNote=Poly-Gln
TgeneATXN2chr12:112120950chr12:111902519ENST000003776171925213_22311051314.0Compositional biasNote=Poly-Ser
TgeneATXN2chr12:112120950chr12:111902519ENST00000377617192547_15811051314.0Compositional biasNote=Pro-rich
TgeneATXN2chr12:112120950chr12:111902519ENST000003776171925551_73411051314.0Compositional biasNote=Pro-rich
TgeneATXN2chr12:112120950chr12:111902519ENST00000377617192555_6411051314.0Compositional biasNote=Poly-Pro
TgeneATXN2chr12:112120950chr12:111902519ENST000003776171925929_108511051314.0Compositional biasNote=Pro-rich
TgeneATXN2chr12:112120950chr12:111902519ENST000005501041824166_18710851015.3333333333334Compositional biasNote=Poly-Gln
TgeneATXN2chr12:112120950chr12:111902519ENST000005501041824213_22310851015.3333333333334Compositional biasNote=Poly-Ser
TgeneATXN2chr12:112120950chr12:111902519ENST00000550104182447_15810851015.3333333333334Compositional biasNote=Pro-rich
TgeneATXN2chr12:112120950chr12:111902519ENST000005501041824551_73410851015.3333333333334Compositional biasNote=Pro-rich
TgeneATXN2chr12:112120950chr12:111902519ENST00000550104182455_6410851015.3333333333334Compositional biasNote=Poly-Pro
TgeneATXN2chr12:112120950chr12:111902519ENST000005501041824929_108510851015.3333333333334Compositional biasNote=Pro-rich


Top

Fusion Gene Sequence for BRAP-ATXN2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>10138_10138_1_BRAP-ATXN2_BRAP_chr12_112120950_ENST00000327551_ATXN2_chr12_111895163_ENST00000377617_length(transcript)=1465nt_BP=295nt
AGCGCCGCGGGTGAGTCCCGCGGCCTCGCCGCATTCCCTGTAGCCGGGTCTGGGCCCGGAGGGCTTCCCTTCCCAAAGCACTGGCCCGGG
AAAAGCCCGCGGCGAGGGCTGTTGCCCAGGAAGACACGGAGAGCCGGGGAAATGTCTGATGAGGAGATAAAAAAGACGACACTAGCCTCA
GCTGTAGCCTGTTTAGAAGGCAAGTCACCAGGAGAGAAAGTAGCGATTATCCATCAGCATCTCGGCCGTCGAGAAATGACAGATGTGATC
ATTGAGACCATGAAGTCCAACCCAGTTTCCACGGGCTCCCTTGCTCAGCAGTATGCGCACCCTAACGCTACCCTGCACCCACATACTCCA
CACCCTCAGCCTTCAGCTACCCCCACTGGACAGCAGCAAAGCCAACATGGTGGAAGTCATCCTGCACCCAGTCCTGTTCAGCACCATCAG
CACCAGGCCGCCCAGGCTCTCCATCTGGCCAGTCCACAGCAGCAGTCAGCCATTTACCACGCGGGGCTTGCGCCAACTCCACCCTCCATG
ACACCTGCCTCCAACACGCAGTCGCCACAGAATAGTTTCCCAGCAGCACAACAGACTGTCTTTACGATCCATCCTTCTCACGTTCAGCCG
GCGTATACCAACCCACCCCACATGGCCCACGTACCTCAGGCTCATGTACAGTCAGGAATGGTTCCTTCTCATCCAACTGCCCATGCGCCA
ATGATGCTAATGACGACACAGCCACCCGGCGGTCCCCAGGCCGCCCTCGCTCAAAGTGCACTACAGCCCATTCCAGTCTCGACAACAGCG
CATTTCCCCTATATGACGCACCCTTCAGTACAAGCCCACCACCAACAGCAGTTGTAAGGCTGCCCTGGAGGAACCGAAAGGCCAAATTCC
CTCCTCCCTTCTACTGCTTCTACCAACTGGAAGCACAGAAAACTAGAATTTCATTTATTTTGTTTTTAAAATATATATGTTGATTTCTTG
TAACATCCAATAGGAATGCTAACAGTTCACTTGCAGTGGAAGATACTTGGACCGAGTAGAGGCATTTAGGAACTTGGGGGCTATTCCATA
ATTCCATATGCTGTTTCAGAGTCCCGCAGGTACCCCAGCTCTGCTTGCCGAAACTGGAAGTTATTTATTTTTTAATAACCCTTGAAAGTC
ATGAACACATCAGCTAGCAAAAGAAGTAACAAGAGTGATTCTTGCTGCTATTACTGCTAAAAAAAAAAAAAAAAAAAAATCAAGACTTGG
AACGCCCTTTTACTAAACTTGACAAAGTTTCAGTAAATTCTTACCGTCAAACTGACGGATTATTATTTATAAATCAAGTTTGATGAGGTG
ATCACTGTCTACAGTGGTTCAACTTTTAAGTTAAGGGAAAAACTTTTACTTTGTAGATAATATAAAATAAAAACTTAAAAAAAATTTAAA

>10138_10138_1_BRAP-ATXN2_BRAP_chr12_112120950_ENST00000327551_ATXN2_chr12_111895163_ENST00000377617_length(amino acids)=252AA_BP=8
MLPRKTRRAGEMSDEEIKKTTLASAVACLEGKSPGEKVAIIHQHLGRREMTDVIIETMKSNPVSTGSLAQQYAHPNATLHPHTPHPQPSA
TPTGQQQSQHGGSHPAPSPVQHHQHQAAQALHLASPQQQSAIYHAGLAPTPPSMTPASNTQSPQNSFPAAQQTVFTIHPSHVQPAYTNPP

--------------------------------------------------------------
>10138_10138_2_BRAP-ATXN2_BRAP_chr12_112120950_ENST00000327551_ATXN2_chr12_111895163_ENST00000389153_length(transcript)=1465nt_BP=295nt
AGCGCCGCGGGTGAGTCCCGCGGCCTCGCCGCATTCCCTGTAGCCGGGTCTGGGCCCGGAGGGCTTCCCTTCCCAAAGCACTGGCCCGGG
AAAAGCCCGCGGCGAGGGCTGTTGCCCAGGAAGACACGGAGAGCCGGGGAAATGTCTGATGAGGAGATAAAAAAGACGACACTAGCCTCA
GCTGTAGCCTGTTTAGAAGGCAAGTCACCAGGAGAGAAAGTAGCGATTATCCATCAGCATCTCGGCCGTCGAGAAATGACAGATGTGATC
ATTGAGACCATGAAGTCCAACCCAGTTTCCACGGGCTCCCTTGCTCAGCAGTATGCGCACCCTAACGCTACCCTGCACCCACATACTCCA
CACCCTCAGCCTTCAGCTACCCCCACTGGACAGCAGCAAAGCCAACATGGTGGAAGTCATCCTGCACCCAGTCCTGTTCAGCACCATCAG
CACCAGGCCGCCCAGGCTCTCCATCTGGCCAGTCCACAGCAGCAGTCAGCCATTTACCACGCGGGGCTTGCGCCAACTCCACCCTCCATG
ACACCTGCCTCCAACACGCAGTCGCCACAGAATAGTTTCCCAGCAGCACAACAGACTGTCTTTACGATCCATCCTTCTCACGTTCAGCCG
GCGTATACCAACCCACCCCACATGGCCCACGTACCTCAGGCTCATGTACAGTCAGGAATGGTTCCTTCTCATCCAACTGCCCATGCGCCA
ATGATGCTAATGACGACACAGCCACCCGGCGGTCCCCAGGCCGCCCTCGCTCAAAGTGCACTACAGCCCATTCCAGTCTCGACAACAGCG
CATTTCCCCTATATGACGCACCCTTCAGTACAAGCCCACCACCAACAGCAGTTGTAAGGCTGCCCTGGAGGAACCGAAAGGCCAAATTCC
CTCCTCCCTTCTACTGCTTCTACCAACTGGAAGCACAGAAAACTAGAATTTCATTTATTTTGTTTTTAAAATATATATGTTGATTTCTTG
TAACATCCAATAGGAATGCTAACAGTTCACTTGCAGTGGAAGATACTTGGACCGAGTAGAGGCATTTAGGAACTTGGGGGCTATTCCATA
ATTCCATATGCTGTTTCAGAGTCCCGCAGGTACCCCAGCTCTGCTTGCCGAAACTGGAAGTTATTTATTTTTTAATAACCCTTGAAAGTC
ATGAACACATCAGCTAGCAAAAGAAGTAACAAGAGTGATTCTTGCTGCTATTACTGCTAAAAAAAAAAAAAAAAAAAAATCAAGACTTGG
AACGCCCTTTTACTAAACTTGACAAAGTTTCAGTAAATTCTTACCGTCAAACTGACGGATTATTATTTATAAATCAAGTTTGATGAGGTG
ATCACTGTCTACAGTGGTTCAACTTTTAAGTTAAGGGAAAAACTTTTACTTTGTAGATAATATAAAATAAAAACTTAAAAAAAATTTAAA

>10138_10138_2_BRAP-ATXN2_BRAP_chr12_112120950_ENST00000327551_ATXN2_chr12_111895163_ENST00000389153_length(amino acids)=252AA_BP=8
MLPRKTRRAGEMSDEEIKKTTLASAVACLEGKSPGEKVAIIHQHLGRREMTDVIIETMKSNPVSTGSLAQQYAHPNATLHPHTPHPQPSA
TPTGQQQSQHGGSHPAPSPVQHHQHQAAQALHLASPQQQSAIYHAGLAPTPPSMTPASNTQSPQNSFPAAQQTVFTIHPSHVQPAYTNPP

--------------------------------------------------------------
>10138_10138_3_BRAP-ATXN2_BRAP_chr12_112120950_ENST00000327551_ATXN2_chr12_111895163_ENST00000608853_length(transcript)=1465nt_BP=295nt
AGCGCCGCGGGTGAGTCCCGCGGCCTCGCCGCATTCCCTGTAGCCGGGTCTGGGCCCGGAGGGCTTCCCTTCCCAAAGCACTGGCCCGGG
AAAAGCCCGCGGCGAGGGCTGTTGCCCAGGAAGACACGGAGAGCCGGGGAAATGTCTGATGAGGAGATAAAAAAGACGACACTAGCCTCA
GCTGTAGCCTGTTTAGAAGGCAAGTCACCAGGAGAGAAAGTAGCGATTATCCATCAGCATCTCGGCCGTCGAGAAATGACAGATGTGATC
ATTGAGACCATGAAGTCCAACCCAGTTTCCACGGGCTCCCTTGCTCAGCAGTATGCGCACCCTAACGCTACCCTGCACCCACATACTCCA
CACCCTCAGCCTTCAGCTACCCCCACTGGACAGCAGCAAAGCCAACATGGTGGAAGTCATCCTGCACCCAGTCCTGTTCAGCACCATCAG
CACCAGGCCGCCCAGGCTCTCCATCTGGCCAGTCCACAGCAGCAGTCAGCCATTTACCACGCGGGGCTTGCGCCAACTCCACCCTCCATG
ACACCTGCCTCCAACACGCAGTCGCCACAGAATAGTTTCCCAGCAGCACAACAGACTGTCTTTACGATCCATCCTTCTCACGTTCAGCCG
GCGTATACCAACCCACCCCACATGGCCCACGTACCTCAGGCTCATGTACAGTCAGGAATGGTTCCTTCTCATCCAACTGCCCATGCGCCA
ATGATGCTAATGACGACACAGCCACCCGGCGGTCCCCAGGCCGCCCTCGCTCAAAGTGCACTACAGCCCATTCCAGTCTCGACAACAGCG
CATTTCCCCTATATGACGCACCCTTCAGTACAAGCCCACCACCAACAGCAGTTGTAAGGCTGCCCTGGAGGAACCGAAAGGCCAAATTCC
CTCCTCCCTTCTACTGCTTCTACCAACTGGAAGCACAGAAAACTAGAATTTCATTTATTTTGTTTTTAAAATATATATGTTGATTTCTTG
TAACATCCAATAGGAATGCTAACAGTTCACTTGCAGTGGAAGATACTTGGACCGAGTAGAGGCATTTAGGAACTTGGGGGCTATTCCATA
ATTCCATATGCTGTTTCAGAGTCCCGCAGGTACCCCAGCTCTGCTTGCCGAAACTGGAAGTTATTTATTTTTTAATAACCCTTGAAAGTC
ATGAACACATCAGCTAGCAAAAGAAGTAACAAGAGTGATTCTTGCTGCTATTACTGCTAAAAAAAAAAAAAAAAAAAAATCAAGACTTGG
AACGCCCTTTTACTAAACTTGACAAAGTTTCAGTAAATTCTTACCGTCAAACTGACGGATTATTATTTATAAATCAAGTTTGATGAGGTG
ATCACTGTCTACAGTGGTTCAACTTTTAAGTTAAGGGAAAAACTTTTACTTTGTAGATAATATAAAATAAAAACTTAAAAAAAATTTAAA

>10138_10138_3_BRAP-ATXN2_BRAP_chr12_112120950_ENST00000327551_ATXN2_chr12_111895163_ENST00000608853_length(amino acids)=252AA_BP=8
MLPRKTRRAGEMSDEEIKKTTLASAVACLEGKSPGEKVAIIHQHLGRREMTDVIIETMKSNPVSTGSLAQQYAHPNATLHPHTPHPQPSA
TPTGQQQSQHGGSHPAPSPVQHHQHQAAQALHLASPQQQSAIYHAGLAPTPPSMTPASNTQSPQNSFPAAQQTVFTIHPSHVQPAYTNPP

--------------------------------------------------------------
>10138_10138_4_BRAP-ATXN2_BRAP_chr12_112120950_ENST00000327551_ATXN2_chr12_111902519_ENST00000377617_length(transcript)=1519nt_BP=295nt
AGCGCCGCGGGTGAGTCCCGCGGCCTCGCCGCATTCCCTGTAGCCGGGTCTGGGCCCGGAGGGCTTCCCTTCCCAAAGCACTGGCCCGGG
AAAAGCCCGCGGCGAGGGCTGTTGCCCAGGAAGACACGGAGAGCCGGGGAAATGTCTGATGAGGAGATAAAAAAGACGACACTAGCCTCA
GCTGTAGCCTGTTTAGAAGGCAAGTCACCAGGAGAGAAAGTAGCGATTATCCATCAGCATCTCGGCCGTCGAGAAATGACAGATGTGATC
ATTGAGACCATGAAGTCCAACCCAGCATGTCCCAAATTACCATACAACAAGGAGACAAGCCCTTCTTTCTACTTTGCCATTTCCACGGGC
TCCCTTGCTCAGCAGTATGCGCACCCTAACGCTACCCTGCACCCACATACTCCACACCCTCAGCCTTCAGCTACCCCCACTGGACAGCAG
CAAAGCCAACATGGTGGAAGTCATCCTGCACCCAGTCCTGTTCAGCACCATCAGCACCAGGCCGCCCAGGCTCTCCATCTGGCCAGTCCA
CAGCAGCAGTCAGCCATTTACCACGCGGGGCTTGCGCCAACTCCACCCTCCATGACACCTGCCTCCAACACGCAGTCGCCACAGAATAGT
TTCCCAGCAGCACAACAGACTGTCTTTACGATCCATCCTTCTCACGTTCAGCCGGCGTATACCAACCCACCCCACATGGCCCACGTACCT
CAGGCTCATGTACAGTCAGGAATGGTTCCTTCTCATCCAACTGCCCATGCGCCAATGATGCTAATGACGACACAGCCACCCGGCGGTCCC
CAGGCCGCCCTCGCTCAAAGTGCACTACAGCCCATTCCAGTCTCGACAACAGCGCATTTCCCCTATATGACGCACCCTTCAGTACAAGCC
CACCACCAACAGCAGTTGTAAGGCTGCCCTGGAGGAACCGAAAGGCCAAATTCCCTCCTCCCTTCTACTGCTTCTACCAACTGGAAGCAC
AGAAAACTAGAATTTCATTTATTTTGTTTTTAAAATATATATGTTGATTTCTTGTAACATCCAATAGGAATGCTAACAGTTCACTTGCAG
TGGAAGATACTTGGACCGAGTAGAGGCATTTAGGAACTTGGGGGCTATTCCATAATTCCATATGCTGTTTCAGAGTCCCGCAGGTACCCC
AGCTCTGCTTGCCGAAACTGGAAGTTATTTATTTTTTAATAACCCTTGAAAGTCATGAACACATCAGCTAGCAAAAGAAGTAACAAGAGT
GATTCTTGCTGCTATTACTGCTAAAAAAAAAAAAAAAAAAAAATCAAGACTTGGAACGCCCTTTTACTAAACTTGACAAAGTTTCAGTAA
ATTCTTACCGTCAAACTGACGGATTATTATTTATAAATCAAGTTTGATGAGGTGATCACTGTCTACAGTGGTTCAACTTTTAAGTTAAGG

>10138_10138_4_BRAP-ATXN2_BRAP_chr12_112120950_ENST00000327551_ATXN2_chr12_111902519_ENST00000377617_length(amino acids)=270AA_BP=8
MLPRKTRRAGEMSDEEIKKTTLASAVACLEGKSPGEKVAIIHQHLGRREMTDVIIETMKSNPACPKLPYNKETSPSFYFAISTGSLAQQY
AHPNATLHPHTPHPQPSATPTGQQQSQHGGSHPAPSPVQHHQHQAAQALHLASPQQQSAIYHAGLAPTPPSMTPASNTQSPQNSFPAAQQ
TVFTIHPSHVQPAYTNPPHMAHVPQAHVQSGMVPSHPTAHAPMMLMTTQPPGGPQAALAQSALQPIPVSTTAHFPYMTHPSVQAHHQQQL

--------------------------------------------------------------
>10138_10138_5_BRAP-ATXN2_BRAP_chr12_112120950_ENST00000327551_ATXN2_chr12_111902519_ENST00000389153_length(transcript)=1519nt_BP=295nt
AGCGCCGCGGGTGAGTCCCGCGGCCTCGCCGCATTCCCTGTAGCCGGGTCTGGGCCCGGAGGGCTTCCCTTCCCAAAGCACTGGCCCGGG
AAAAGCCCGCGGCGAGGGCTGTTGCCCAGGAAGACACGGAGAGCCGGGGAAATGTCTGATGAGGAGATAAAAAAGACGACACTAGCCTCA
GCTGTAGCCTGTTTAGAAGGCAAGTCACCAGGAGAGAAAGTAGCGATTATCCATCAGCATCTCGGCCGTCGAGAAATGACAGATGTGATC
ATTGAGACCATGAAGTCCAACCCAGCATGTCCCAAATTACCATACAACAAGGAGACAAGCCCTTCTTTCTACTTTGCCATTTCCACGGGC
TCCCTTGCTCAGCAGTATGCGCACCCTAACGCTACCCTGCACCCACATACTCCACACCCTCAGCCTTCAGCTACCCCCACTGGACAGCAG
CAAAGCCAACATGGTGGAAGTCATCCTGCACCCAGTCCTGTTCAGCACCATCAGCACCAGGCCGCCCAGGCTCTCCATCTGGCCAGTCCA
CAGCAGCAGTCAGCCATTTACCACGCGGGGCTTGCGCCAACTCCACCCTCCATGACACCTGCCTCCAACACGCAGTCGCCACAGAATAGT
TTCCCAGCAGCACAACAGACTGTCTTTACGATCCATCCTTCTCACGTTCAGCCGGCGTATACCAACCCACCCCACATGGCCCACGTACCT
CAGGCTCATGTACAGTCAGGAATGGTTCCTTCTCATCCAACTGCCCATGCGCCAATGATGCTAATGACGACACAGCCACCCGGCGGTCCC
CAGGCCGCCCTCGCTCAAAGTGCACTACAGCCCATTCCAGTCTCGACAACAGCGCATTTCCCCTATATGACGCACCCTTCAGTACAAGCC
CACCACCAACAGCAGTTGTAAGGCTGCCCTGGAGGAACCGAAAGGCCAAATTCCCTCCTCCCTTCTACTGCTTCTACCAACTGGAAGCAC
AGAAAACTAGAATTTCATTTATTTTGTTTTTAAAATATATATGTTGATTTCTTGTAACATCCAATAGGAATGCTAACAGTTCACTTGCAG
TGGAAGATACTTGGACCGAGTAGAGGCATTTAGGAACTTGGGGGCTATTCCATAATTCCATATGCTGTTTCAGAGTCCCGCAGGTACCCC
AGCTCTGCTTGCCGAAACTGGAAGTTATTTATTTTTTAATAACCCTTGAAAGTCATGAACACATCAGCTAGCAAAAGAAGTAACAAGAGT
GATTCTTGCTGCTATTACTGCTAAAAAAAAAAAAAAAAAAAAATCAAGACTTGGAACGCCCTTTTACTAAACTTGACAAAGTTTCAGTAA
ATTCTTACCGTCAAACTGACGGATTATTATTTATAAATCAAGTTTGATGAGGTGATCACTGTCTACAGTGGTTCAACTTTTAAGTTAAGG

>10138_10138_5_BRAP-ATXN2_BRAP_chr12_112120950_ENST00000327551_ATXN2_chr12_111902519_ENST00000389153_length(amino acids)=270AA_BP=8
MLPRKTRRAGEMSDEEIKKTTLASAVACLEGKSPGEKVAIIHQHLGRREMTDVIIETMKSNPACPKLPYNKETSPSFYFAISTGSLAQQY
AHPNATLHPHTPHPQPSATPTGQQQSQHGGSHPAPSPVQHHQHQAAQALHLASPQQQSAIYHAGLAPTPPSMTPASNTQSPQNSFPAAQQ
TVFTIHPSHVQPAYTNPPHMAHVPQAHVQSGMVPSHPTAHAPMMLMTTQPPGGPQAALAQSALQPIPVSTTAHFPYMTHPSVQAHHQQQL

--------------------------------------------------------------
>10138_10138_6_BRAP-ATXN2_BRAP_chr12_112120950_ENST00000327551_ATXN2_chr12_111902519_ENST00000608853_length(transcript)=1519nt_BP=295nt
AGCGCCGCGGGTGAGTCCCGCGGCCTCGCCGCATTCCCTGTAGCCGGGTCTGGGCCCGGAGGGCTTCCCTTCCCAAAGCACTGGCCCGGG
AAAAGCCCGCGGCGAGGGCTGTTGCCCAGGAAGACACGGAGAGCCGGGGAAATGTCTGATGAGGAGATAAAAAAGACGACACTAGCCTCA
GCTGTAGCCTGTTTAGAAGGCAAGTCACCAGGAGAGAAAGTAGCGATTATCCATCAGCATCTCGGCCGTCGAGAAATGACAGATGTGATC
ATTGAGACCATGAAGTCCAACCCAGCATGTCCCAAATTACCATACAACAAGGAGACAAGCCCTTCTTTCTACTTTGCCATTTCCACGGGC
TCCCTTGCTCAGCAGTATGCGCACCCTAACGCTACCCTGCACCCACATACTCCACACCCTCAGCCTTCAGCTACCCCCACTGGACAGCAG
CAAAGCCAACATGGTGGAAGTCATCCTGCACCCAGTCCTGTTCAGCACCATCAGCACCAGGCCGCCCAGGCTCTCCATCTGGCCAGTCCA
CAGCAGCAGTCAGCCATTTACCACGCGGGGCTTGCGCCAACTCCACCCTCCATGACACCTGCCTCCAACACGCAGTCGCCACAGAATAGT
TTCCCAGCAGCACAACAGACTGTCTTTACGATCCATCCTTCTCACGTTCAGCCGGCGTATACCAACCCACCCCACATGGCCCACGTACCT
CAGGCTCATGTACAGTCAGGAATGGTTCCTTCTCATCCAACTGCCCATGCGCCAATGATGCTAATGACGACACAGCCACCCGGCGGTCCC
CAGGCCGCCCTCGCTCAAAGTGCACTACAGCCCATTCCAGTCTCGACAACAGCGCATTTCCCCTATATGACGCACCCTTCAGTACAAGCC
CACCACCAACAGCAGTTGTAAGGCTGCCCTGGAGGAACCGAAAGGCCAAATTCCCTCCTCCCTTCTACTGCTTCTACCAACTGGAAGCAC
AGAAAACTAGAATTTCATTTATTTTGTTTTTAAAATATATATGTTGATTTCTTGTAACATCCAATAGGAATGCTAACAGTTCACTTGCAG
TGGAAGATACTTGGACCGAGTAGAGGCATTTAGGAACTTGGGGGCTATTCCATAATTCCATATGCTGTTTCAGAGTCCCGCAGGTACCCC
AGCTCTGCTTGCCGAAACTGGAAGTTATTTATTTTTTAATAACCCTTGAAAGTCATGAACACATCAGCTAGCAAAAGAAGTAACAAGAGT
GATTCTTGCTGCTATTACTGCTAAAAAAAAAAAAAAAAAAAAATCAAGACTTGGAACGCCCTTTTACTAAACTTGACAAAGTTTCAGTAA
ATTCTTACCGTCAAACTGACGGATTATTATTTATAAATCAAGTTTGATGAGGTGATCACTGTCTACAGTGGTTCAACTTTTAAGTTAAGG

>10138_10138_6_BRAP-ATXN2_BRAP_chr12_112120950_ENST00000327551_ATXN2_chr12_111902519_ENST00000608853_length(amino acids)=270AA_BP=8
MLPRKTRRAGEMSDEEIKKTTLASAVACLEGKSPGEKVAIIHQHLGRREMTDVIIETMKSNPACPKLPYNKETSPSFYFAISTGSLAQQY
AHPNATLHPHTPHPQPSATPTGQQQSQHGGSHPAPSPVQHHQHQAAQALHLASPQQQSAIYHAGLAPTPPSMTPASNTQSPQNSFPAAQQ
TVFTIHPSHVQPAYTNPPHMAHVPQAHVQSGMVPSHPTAHAPMMLMTTQPPGGPQAALAQSALQPIPVSTTAHFPYMTHPSVQAHHQQQL

--------------------------------------------------------------
>10138_10138_7_BRAP-ATXN2_BRAP_chr12_112120950_ENST00000419234_ATXN2_chr12_111895163_ENST00000377617_length(transcript)=1608nt_BP=438nt
AGCGACGGCGGCCGGGAGGCGGAAGTGGAGGTTGTTGTGGCTCCGAGGGCTGTTCGAGGAGCTGCTGCTGCTGAGGCGGCGGCAACTGCA
TTGAGGTGGTGGCGGCGCTGCCGGCCCCGGGCCGCTCGGCCTCTCGGCTCGCCTTCCAGCCTCGCCTGAGCCCGCCGGGGCCCGCGCCGG
CCAGCGCCTGCCCTATGAGTGTGTCACTGGTTGTTATCCGATTGGAGCTCGCGGAACACTCGCCTGTCCCCGCCGGCTTCGGCTTCAGCG
CCGCGGCCGGGGAAATGTCTGATGAGGAGATAAAAAAGACGACACTAGCCTCAGCTGTAGCCTGTTTAGAAGGCAAGTCACCAGGAGAGA
AAGTAGCGATTATCCATCAGCATCTCGGCCGTCGAGAAATGACAGATGTGATCATTGAGACCATGAAGTCCAACCCAGTTTCCACGGGCT
CCCTTGCTCAGCAGTATGCGCACCCTAACGCTACCCTGCACCCACATACTCCACACCCTCAGCCTTCAGCTACCCCCACTGGACAGCAGC
AAAGCCAACATGGTGGAAGTCATCCTGCACCCAGTCCTGTTCAGCACCATCAGCACCAGGCCGCCCAGGCTCTCCATCTGGCCAGTCCAC
AGCAGCAGTCAGCCATTTACCACGCGGGGCTTGCGCCAACTCCACCCTCCATGACACCTGCCTCCAACACGCAGTCGCCACAGAATAGTT
TCCCAGCAGCACAACAGACTGTCTTTACGATCCATCCTTCTCACGTTCAGCCGGCGTATACCAACCCACCCCACATGGCCCACGTACCTC
AGGCTCATGTACAGTCAGGAATGGTTCCTTCTCATCCAACTGCCCATGCGCCAATGATGCTAATGACGACACAGCCACCCGGCGGTCCCC
AGGCCGCCCTCGCTCAAAGTGCACTACAGCCCATTCCAGTCTCGACAACAGCGCATTTCCCCTATATGACGCACCCTTCAGTACAAGCCC
ACCACCAACAGCAGTTGTAAGGCTGCCCTGGAGGAACCGAAAGGCCAAATTCCCTCCTCCCTTCTACTGCTTCTACCAACTGGAAGCACA
GAAAACTAGAATTTCATTTATTTTGTTTTTAAAATATATATGTTGATTTCTTGTAACATCCAATAGGAATGCTAACAGTTCACTTGCAGT
GGAAGATACTTGGACCGAGTAGAGGCATTTAGGAACTTGGGGGCTATTCCATAATTCCATATGCTGTTTCAGAGTCCCGCAGGTACCCCA
GCTCTGCTTGCCGAAACTGGAAGTTATTTATTTTTTAATAACCCTTGAAAGTCATGAACACATCAGCTAGCAAAAGAAGTAACAAGAGTG
ATTCTTGCTGCTATTACTGCTAAAAAAAAAAAAAAAAAAAAATCAAGACTTGGAACGCCCTTTTACTAAACTTGACAAAGTTTCAGTAAA
TTCTTACCGTCAAACTGACGGATTATTATTTATAAATCAAGTTTGATGAGGTGATCACTGTCTACAGTGGTTCAACTTTTAAGTTAAGGG

>10138_10138_7_BRAP-ATXN2_BRAP_chr12_112120950_ENST00000419234_ATXN2_chr12_111895163_ENST00000377617_length(amino acids)=300AA_BP=1
MPAPGRSASRLAFQPRLSPPGPAPASACPMSVSLVVIRLELAEHSPVPAGFGFSAAAGEMSDEEIKKTTLASAVACLEGKSPGEKVAIIH
QHLGRREMTDVIIETMKSNPVSTGSLAQQYAHPNATLHPHTPHPQPSATPTGQQQSQHGGSHPAPSPVQHHQHQAAQALHLASPQQQSAI
YHAGLAPTPPSMTPASNTQSPQNSFPAAQQTVFTIHPSHVQPAYTNPPHMAHVPQAHVQSGMVPSHPTAHAPMMLMTTQPPGGPQAALAQ

--------------------------------------------------------------
>10138_10138_8_BRAP-ATXN2_BRAP_chr12_112120950_ENST00000419234_ATXN2_chr12_111895163_ENST00000389153_length(transcript)=1608nt_BP=438nt
AGCGACGGCGGCCGGGAGGCGGAAGTGGAGGTTGTTGTGGCTCCGAGGGCTGTTCGAGGAGCTGCTGCTGCTGAGGCGGCGGCAACTGCA
TTGAGGTGGTGGCGGCGCTGCCGGCCCCGGGCCGCTCGGCCTCTCGGCTCGCCTTCCAGCCTCGCCTGAGCCCGCCGGGGCCCGCGCCGG
CCAGCGCCTGCCCTATGAGTGTGTCACTGGTTGTTATCCGATTGGAGCTCGCGGAACACTCGCCTGTCCCCGCCGGCTTCGGCTTCAGCG
CCGCGGCCGGGGAAATGTCTGATGAGGAGATAAAAAAGACGACACTAGCCTCAGCTGTAGCCTGTTTAGAAGGCAAGTCACCAGGAGAGA
AAGTAGCGATTATCCATCAGCATCTCGGCCGTCGAGAAATGACAGATGTGATCATTGAGACCATGAAGTCCAACCCAGTTTCCACGGGCT
CCCTTGCTCAGCAGTATGCGCACCCTAACGCTACCCTGCACCCACATACTCCACACCCTCAGCCTTCAGCTACCCCCACTGGACAGCAGC
AAAGCCAACATGGTGGAAGTCATCCTGCACCCAGTCCTGTTCAGCACCATCAGCACCAGGCCGCCCAGGCTCTCCATCTGGCCAGTCCAC
AGCAGCAGTCAGCCATTTACCACGCGGGGCTTGCGCCAACTCCACCCTCCATGACACCTGCCTCCAACACGCAGTCGCCACAGAATAGTT
TCCCAGCAGCACAACAGACTGTCTTTACGATCCATCCTTCTCACGTTCAGCCGGCGTATACCAACCCACCCCACATGGCCCACGTACCTC
AGGCTCATGTACAGTCAGGAATGGTTCCTTCTCATCCAACTGCCCATGCGCCAATGATGCTAATGACGACACAGCCACCCGGCGGTCCCC
AGGCCGCCCTCGCTCAAAGTGCACTACAGCCCATTCCAGTCTCGACAACAGCGCATTTCCCCTATATGACGCACCCTTCAGTACAAGCCC
ACCACCAACAGCAGTTGTAAGGCTGCCCTGGAGGAACCGAAAGGCCAAATTCCCTCCTCCCTTCTACTGCTTCTACCAACTGGAAGCACA
GAAAACTAGAATTTCATTTATTTTGTTTTTAAAATATATATGTTGATTTCTTGTAACATCCAATAGGAATGCTAACAGTTCACTTGCAGT
GGAAGATACTTGGACCGAGTAGAGGCATTTAGGAACTTGGGGGCTATTCCATAATTCCATATGCTGTTTCAGAGTCCCGCAGGTACCCCA
GCTCTGCTTGCCGAAACTGGAAGTTATTTATTTTTTAATAACCCTTGAAAGTCATGAACACATCAGCTAGCAAAAGAAGTAACAAGAGTG
ATTCTTGCTGCTATTACTGCTAAAAAAAAAAAAAAAAAAAAATCAAGACTTGGAACGCCCTTTTACTAAACTTGACAAAGTTTCAGTAAA
TTCTTACCGTCAAACTGACGGATTATTATTTATAAATCAAGTTTGATGAGGTGATCACTGTCTACAGTGGTTCAACTTTTAAGTTAAGGG

>10138_10138_8_BRAP-ATXN2_BRAP_chr12_112120950_ENST00000419234_ATXN2_chr12_111895163_ENST00000389153_length(amino acids)=300AA_BP=1
MPAPGRSASRLAFQPRLSPPGPAPASACPMSVSLVVIRLELAEHSPVPAGFGFSAAAGEMSDEEIKKTTLASAVACLEGKSPGEKVAIIH
QHLGRREMTDVIIETMKSNPVSTGSLAQQYAHPNATLHPHTPHPQPSATPTGQQQSQHGGSHPAPSPVQHHQHQAAQALHLASPQQQSAI
YHAGLAPTPPSMTPASNTQSPQNSFPAAQQTVFTIHPSHVQPAYTNPPHMAHVPQAHVQSGMVPSHPTAHAPMMLMTTQPPGGPQAALAQ

--------------------------------------------------------------
>10138_10138_9_BRAP-ATXN2_BRAP_chr12_112120950_ENST00000419234_ATXN2_chr12_111895163_ENST00000608853_length(transcript)=1608nt_BP=438nt
AGCGACGGCGGCCGGGAGGCGGAAGTGGAGGTTGTTGTGGCTCCGAGGGCTGTTCGAGGAGCTGCTGCTGCTGAGGCGGCGGCAACTGCA
TTGAGGTGGTGGCGGCGCTGCCGGCCCCGGGCCGCTCGGCCTCTCGGCTCGCCTTCCAGCCTCGCCTGAGCCCGCCGGGGCCCGCGCCGG
CCAGCGCCTGCCCTATGAGTGTGTCACTGGTTGTTATCCGATTGGAGCTCGCGGAACACTCGCCTGTCCCCGCCGGCTTCGGCTTCAGCG
CCGCGGCCGGGGAAATGTCTGATGAGGAGATAAAAAAGACGACACTAGCCTCAGCTGTAGCCTGTTTAGAAGGCAAGTCACCAGGAGAGA
AAGTAGCGATTATCCATCAGCATCTCGGCCGTCGAGAAATGACAGATGTGATCATTGAGACCATGAAGTCCAACCCAGTTTCCACGGGCT
CCCTTGCTCAGCAGTATGCGCACCCTAACGCTACCCTGCACCCACATACTCCACACCCTCAGCCTTCAGCTACCCCCACTGGACAGCAGC
AAAGCCAACATGGTGGAAGTCATCCTGCACCCAGTCCTGTTCAGCACCATCAGCACCAGGCCGCCCAGGCTCTCCATCTGGCCAGTCCAC
AGCAGCAGTCAGCCATTTACCACGCGGGGCTTGCGCCAACTCCACCCTCCATGACACCTGCCTCCAACACGCAGTCGCCACAGAATAGTT
TCCCAGCAGCACAACAGACTGTCTTTACGATCCATCCTTCTCACGTTCAGCCGGCGTATACCAACCCACCCCACATGGCCCACGTACCTC
AGGCTCATGTACAGTCAGGAATGGTTCCTTCTCATCCAACTGCCCATGCGCCAATGATGCTAATGACGACACAGCCACCCGGCGGTCCCC
AGGCCGCCCTCGCTCAAAGTGCACTACAGCCCATTCCAGTCTCGACAACAGCGCATTTCCCCTATATGACGCACCCTTCAGTACAAGCCC
ACCACCAACAGCAGTTGTAAGGCTGCCCTGGAGGAACCGAAAGGCCAAATTCCCTCCTCCCTTCTACTGCTTCTACCAACTGGAAGCACA
GAAAACTAGAATTTCATTTATTTTGTTTTTAAAATATATATGTTGATTTCTTGTAACATCCAATAGGAATGCTAACAGTTCACTTGCAGT
GGAAGATACTTGGACCGAGTAGAGGCATTTAGGAACTTGGGGGCTATTCCATAATTCCATATGCTGTTTCAGAGTCCCGCAGGTACCCCA
GCTCTGCTTGCCGAAACTGGAAGTTATTTATTTTTTAATAACCCTTGAAAGTCATGAACACATCAGCTAGCAAAAGAAGTAACAAGAGTG
ATTCTTGCTGCTATTACTGCTAAAAAAAAAAAAAAAAAAAAATCAAGACTTGGAACGCCCTTTTACTAAACTTGACAAAGTTTCAGTAAA
TTCTTACCGTCAAACTGACGGATTATTATTTATAAATCAAGTTTGATGAGGTGATCACTGTCTACAGTGGTTCAACTTTTAAGTTAAGGG

>10138_10138_9_BRAP-ATXN2_BRAP_chr12_112120950_ENST00000419234_ATXN2_chr12_111895163_ENST00000608853_length(amino acids)=300AA_BP=1
MPAPGRSASRLAFQPRLSPPGPAPASACPMSVSLVVIRLELAEHSPVPAGFGFSAAAGEMSDEEIKKTTLASAVACLEGKSPGEKVAIIH
QHLGRREMTDVIIETMKSNPVSTGSLAQQYAHPNATLHPHTPHPQPSATPTGQQQSQHGGSHPAPSPVQHHQHQAAQALHLASPQQQSAI
YHAGLAPTPPSMTPASNTQSPQNSFPAAQQTVFTIHPSHVQPAYTNPPHMAHVPQAHVQSGMVPSHPTAHAPMMLMTTQPPGGPQAALAQ

--------------------------------------------------------------
>10138_10138_10_BRAP-ATXN2_BRAP_chr12_112120950_ENST00000419234_ATXN2_chr12_111902519_ENST00000377617_length(transcript)=1662nt_BP=438nt
AGCGACGGCGGCCGGGAGGCGGAAGTGGAGGTTGTTGTGGCTCCGAGGGCTGTTCGAGGAGCTGCTGCTGCTGAGGCGGCGGCAACTGCA
TTGAGGTGGTGGCGGCGCTGCCGGCCCCGGGCCGCTCGGCCTCTCGGCTCGCCTTCCAGCCTCGCCTGAGCCCGCCGGGGCCCGCGCCGG
CCAGCGCCTGCCCTATGAGTGTGTCACTGGTTGTTATCCGATTGGAGCTCGCGGAACACTCGCCTGTCCCCGCCGGCTTCGGCTTCAGCG
CCGCGGCCGGGGAAATGTCTGATGAGGAGATAAAAAAGACGACACTAGCCTCAGCTGTAGCCTGTTTAGAAGGCAAGTCACCAGGAGAGA
AAGTAGCGATTATCCATCAGCATCTCGGCCGTCGAGAAATGACAGATGTGATCATTGAGACCATGAAGTCCAACCCAGCATGTCCCAAAT
TACCATACAACAAGGAGACAAGCCCTTCTTTCTACTTTGCCATTTCCACGGGCTCCCTTGCTCAGCAGTATGCGCACCCTAACGCTACCC
TGCACCCACATACTCCACACCCTCAGCCTTCAGCTACCCCCACTGGACAGCAGCAAAGCCAACATGGTGGAAGTCATCCTGCACCCAGTC
CTGTTCAGCACCATCAGCACCAGGCCGCCCAGGCTCTCCATCTGGCCAGTCCACAGCAGCAGTCAGCCATTTACCACGCGGGGCTTGCGC
CAACTCCACCCTCCATGACACCTGCCTCCAACACGCAGTCGCCACAGAATAGTTTCCCAGCAGCACAACAGACTGTCTTTACGATCCATC
CTTCTCACGTTCAGCCGGCGTATACCAACCCACCCCACATGGCCCACGTACCTCAGGCTCATGTACAGTCAGGAATGGTTCCTTCTCATC
CAACTGCCCATGCGCCAATGATGCTAATGACGACACAGCCACCCGGCGGTCCCCAGGCCGCCCTCGCTCAAAGTGCACTACAGCCCATTC
CAGTCTCGACAACAGCGCATTTCCCCTATATGACGCACCCTTCAGTACAAGCCCACCACCAACAGCAGTTGTAAGGCTGCCCTGGAGGAA
CCGAAAGGCCAAATTCCCTCCTCCCTTCTACTGCTTCTACCAACTGGAAGCACAGAAAACTAGAATTTCATTTATTTTGTTTTTAAAATA
TATATGTTGATTTCTTGTAACATCCAATAGGAATGCTAACAGTTCACTTGCAGTGGAAGATACTTGGACCGAGTAGAGGCATTTAGGAAC
TTGGGGGCTATTCCATAATTCCATATGCTGTTTCAGAGTCCCGCAGGTACCCCAGCTCTGCTTGCCGAAACTGGAAGTTATTTATTTTTT
AATAACCCTTGAAAGTCATGAACACATCAGCTAGCAAAAGAAGTAACAAGAGTGATTCTTGCTGCTATTACTGCTAAAAAAAAAAAAAAA
AAAAAATCAAGACTTGGAACGCCCTTTTACTAAACTTGACAAAGTTTCAGTAAATTCTTACCGTCAAACTGACGGATTATTATTTATAAA
TCAAGTTTGATGAGGTGATCACTGTCTACAGTGGTTCAACTTTTAAGTTAAGGGAAAAACTTTTACTTTGTAGATAATATAAAATAAAAA

>10138_10138_10_BRAP-ATXN2_BRAP_chr12_112120950_ENST00000419234_ATXN2_chr12_111902519_ENST00000377617_length(amino acids)=318AA_BP=1
MPAPGRSASRLAFQPRLSPPGPAPASACPMSVSLVVIRLELAEHSPVPAGFGFSAAAGEMSDEEIKKTTLASAVACLEGKSPGEKVAIIH
QHLGRREMTDVIIETMKSNPACPKLPYNKETSPSFYFAISTGSLAQQYAHPNATLHPHTPHPQPSATPTGQQQSQHGGSHPAPSPVQHHQ
HQAAQALHLASPQQQSAIYHAGLAPTPPSMTPASNTQSPQNSFPAAQQTVFTIHPSHVQPAYTNPPHMAHVPQAHVQSGMVPSHPTAHAP

--------------------------------------------------------------
>10138_10138_11_BRAP-ATXN2_BRAP_chr12_112120950_ENST00000419234_ATXN2_chr12_111902519_ENST00000389153_length(transcript)=1662nt_BP=438nt
AGCGACGGCGGCCGGGAGGCGGAAGTGGAGGTTGTTGTGGCTCCGAGGGCTGTTCGAGGAGCTGCTGCTGCTGAGGCGGCGGCAACTGCA
TTGAGGTGGTGGCGGCGCTGCCGGCCCCGGGCCGCTCGGCCTCTCGGCTCGCCTTCCAGCCTCGCCTGAGCCCGCCGGGGCCCGCGCCGG
CCAGCGCCTGCCCTATGAGTGTGTCACTGGTTGTTATCCGATTGGAGCTCGCGGAACACTCGCCTGTCCCCGCCGGCTTCGGCTTCAGCG
CCGCGGCCGGGGAAATGTCTGATGAGGAGATAAAAAAGACGACACTAGCCTCAGCTGTAGCCTGTTTAGAAGGCAAGTCACCAGGAGAGA
AAGTAGCGATTATCCATCAGCATCTCGGCCGTCGAGAAATGACAGATGTGATCATTGAGACCATGAAGTCCAACCCAGCATGTCCCAAAT
TACCATACAACAAGGAGACAAGCCCTTCTTTCTACTTTGCCATTTCCACGGGCTCCCTTGCTCAGCAGTATGCGCACCCTAACGCTACCC
TGCACCCACATACTCCACACCCTCAGCCTTCAGCTACCCCCACTGGACAGCAGCAAAGCCAACATGGTGGAAGTCATCCTGCACCCAGTC
CTGTTCAGCACCATCAGCACCAGGCCGCCCAGGCTCTCCATCTGGCCAGTCCACAGCAGCAGTCAGCCATTTACCACGCGGGGCTTGCGC
CAACTCCACCCTCCATGACACCTGCCTCCAACACGCAGTCGCCACAGAATAGTTTCCCAGCAGCACAACAGACTGTCTTTACGATCCATC
CTTCTCACGTTCAGCCGGCGTATACCAACCCACCCCACATGGCCCACGTACCTCAGGCTCATGTACAGTCAGGAATGGTTCCTTCTCATC
CAACTGCCCATGCGCCAATGATGCTAATGACGACACAGCCACCCGGCGGTCCCCAGGCCGCCCTCGCTCAAAGTGCACTACAGCCCATTC
CAGTCTCGACAACAGCGCATTTCCCCTATATGACGCACCCTTCAGTACAAGCCCACCACCAACAGCAGTTGTAAGGCTGCCCTGGAGGAA
CCGAAAGGCCAAATTCCCTCCTCCCTTCTACTGCTTCTACCAACTGGAAGCACAGAAAACTAGAATTTCATTTATTTTGTTTTTAAAATA
TATATGTTGATTTCTTGTAACATCCAATAGGAATGCTAACAGTTCACTTGCAGTGGAAGATACTTGGACCGAGTAGAGGCATTTAGGAAC
TTGGGGGCTATTCCATAATTCCATATGCTGTTTCAGAGTCCCGCAGGTACCCCAGCTCTGCTTGCCGAAACTGGAAGTTATTTATTTTTT
AATAACCCTTGAAAGTCATGAACACATCAGCTAGCAAAAGAAGTAACAAGAGTGATTCTTGCTGCTATTACTGCTAAAAAAAAAAAAAAA
AAAAAATCAAGACTTGGAACGCCCTTTTACTAAACTTGACAAAGTTTCAGTAAATTCTTACCGTCAAACTGACGGATTATTATTTATAAA
TCAAGTTTGATGAGGTGATCACTGTCTACAGTGGTTCAACTTTTAAGTTAAGGGAAAAACTTTTACTTTGTAGATAATATAAAATAAAAA

>10138_10138_11_BRAP-ATXN2_BRAP_chr12_112120950_ENST00000419234_ATXN2_chr12_111902519_ENST00000389153_length(amino acids)=318AA_BP=1
MPAPGRSASRLAFQPRLSPPGPAPASACPMSVSLVVIRLELAEHSPVPAGFGFSAAAGEMSDEEIKKTTLASAVACLEGKSPGEKVAIIH
QHLGRREMTDVIIETMKSNPACPKLPYNKETSPSFYFAISTGSLAQQYAHPNATLHPHTPHPQPSATPTGQQQSQHGGSHPAPSPVQHHQ
HQAAQALHLASPQQQSAIYHAGLAPTPPSMTPASNTQSPQNSFPAAQQTVFTIHPSHVQPAYTNPPHMAHVPQAHVQSGMVPSHPTAHAP

--------------------------------------------------------------
>10138_10138_12_BRAP-ATXN2_BRAP_chr12_112120950_ENST00000419234_ATXN2_chr12_111902519_ENST00000608853_length(transcript)=1662nt_BP=438nt
AGCGACGGCGGCCGGGAGGCGGAAGTGGAGGTTGTTGTGGCTCCGAGGGCTGTTCGAGGAGCTGCTGCTGCTGAGGCGGCGGCAACTGCA
TTGAGGTGGTGGCGGCGCTGCCGGCCCCGGGCCGCTCGGCCTCTCGGCTCGCCTTCCAGCCTCGCCTGAGCCCGCCGGGGCCCGCGCCGG
CCAGCGCCTGCCCTATGAGTGTGTCACTGGTTGTTATCCGATTGGAGCTCGCGGAACACTCGCCTGTCCCCGCCGGCTTCGGCTTCAGCG
CCGCGGCCGGGGAAATGTCTGATGAGGAGATAAAAAAGACGACACTAGCCTCAGCTGTAGCCTGTTTAGAAGGCAAGTCACCAGGAGAGA
AAGTAGCGATTATCCATCAGCATCTCGGCCGTCGAGAAATGACAGATGTGATCATTGAGACCATGAAGTCCAACCCAGCATGTCCCAAAT
TACCATACAACAAGGAGACAAGCCCTTCTTTCTACTTTGCCATTTCCACGGGCTCCCTTGCTCAGCAGTATGCGCACCCTAACGCTACCC
TGCACCCACATACTCCACACCCTCAGCCTTCAGCTACCCCCACTGGACAGCAGCAAAGCCAACATGGTGGAAGTCATCCTGCACCCAGTC
CTGTTCAGCACCATCAGCACCAGGCCGCCCAGGCTCTCCATCTGGCCAGTCCACAGCAGCAGTCAGCCATTTACCACGCGGGGCTTGCGC
CAACTCCACCCTCCATGACACCTGCCTCCAACACGCAGTCGCCACAGAATAGTTTCCCAGCAGCACAACAGACTGTCTTTACGATCCATC
CTTCTCACGTTCAGCCGGCGTATACCAACCCACCCCACATGGCCCACGTACCTCAGGCTCATGTACAGTCAGGAATGGTTCCTTCTCATC
CAACTGCCCATGCGCCAATGATGCTAATGACGACACAGCCACCCGGCGGTCCCCAGGCCGCCCTCGCTCAAAGTGCACTACAGCCCATTC
CAGTCTCGACAACAGCGCATTTCCCCTATATGACGCACCCTTCAGTACAAGCCCACCACCAACAGCAGTTGTAAGGCTGCCCTGGAGGAA
CCGAAAGGCCAAATTCCCTCCTCCCTTCTACTGCTTCTACCAACTGGAAGCACAGAAAACTAGAATTTCATTTATTTTGTTTTTAAAATA
TATATGTTGATTTCTTGTAACATCCAATAGGAATGCTAACAGTTCACTTGCAGTGGAAGATACTTGGACCGAGTAGAGGCATTTAGGAAC
TTGGGGGCTATTCCATAATTCCATATGCTGTTTCAGAGTCCCGCAGGTACCCCAGCTCTGCTTGCCGAAACTGGAAGTTATTTATTTTTT
AATAACCCTTGAAAGTCATGAACACATCAGCTAGCAAAAGAAGTAACAAGAGTGATTCTTGCTGCTATTACTGCTAAAAAAAAAAAAAAA
AAAAAATCAAGACTTGGAACGCCCTTTTACTAAACTTGACAAAGTTTCAGTAAATTCTTACCGTCAAACTGACGGATTATTATTTATAAA
TCAAGTTTGATGAGGTGATCACTGTCTACAGTGGTTCAACTTTTAAGTTAAGGGAAAAACTTTTACTTTGTAGATAATATAAAATAAAAA

>10138_10138_12_BRAP-ATXN2_BRAP_chr12_112120950_ENST00000419234_ATXN2_chr12_111902519_ENST00000608853_length(amino acids)=318AA_BP=1
MPAPGRSASRLAFQPRLSPPGPAPASACPMSVSLVVIRLELAEHSPVPAGFGFSAAAGEMSDEEIKKTTLASAVACLEGKSPGEKVAIIH
QHLGRREMTDVIIETMKSNPACPKLPYNKETSPSFYFAISTGSLAQQYAHPNATLHPHTPHPQPSATPTGQQQSQHGGSHPAPSPVQHHQ
HQAAQALHLASPQQQSAIYHAGLAPTPPSMTPASNTQSPQNSFPAAQQTVFTIHPSHVQPAYTNPPHMAHVPQAHVQSGMVPSHPTAHAP

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for BRAP-ATXN2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for BRAP-ATXN2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for BRAP-ATXN2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneBRAPC0027051Myocardial Infarction1CTD_human
HgeneBRAPC0036341Schizophrenia1PSYGENET
TgeneC0752121Spinocerebellar Ataxia Type 23CTD_human;GENOMICS_ENGLAND;ORPHANET
TgeneC0002736Amyotrophic Lateral Sclerosis2CTD_human;ORPHANET
TgeneC0087012Ataxia, Spinocerebellar2CTD_human
TgeneC0752120Spinocerebellar Ataxia Type 12CTD_human
TgeneC0752122Spinocerebellar Ataxia Type 42CTD_human
TgeneC0752123Spinocerebellar Ataxia Type 52CTD_human
TgeneC0752124Spinocerebellar Ataxia Type 6 (disorder)2CTD_human
TgeneC0752125Spinocerebellar Ataxia Type 72CTD_human
TgeneC0017612Glaucoma, Open-Angle1CTD_human
TgeneC0036341Schizophrenia1PSYGENET
TgeneC0271148Secondary Open Angle Glaucoma1CTD_human
TgeneC0339573Glaucoma, Primary Open Angle1CTD_human
TgeneC0393554Amyotrophic Lateral Sclerosis With Dementia1CTD_human
TgeneC0543859Amyotrophic Lateral Sclerosis, Guam Form1CTD_human