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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:CAPZB-UBR4 (FusionGDB2 ID:HG832TG23352)

Fusion Gene Summary for CAPZB-UBR4

check button Fusion gene summary
Fusion gene informationFusion gene name: CAPZB-UBR4
Fusion gene ID: hg832tg23352
HgeneTgene
Gene symbol

CAPZB

UBR4

Gene ID

832

23352

Gene namecapping actin protein of muscle Z-line subunit betaubiquitin protein ligase E3 component n-recognin 4
SynonymsCAPB|CAPPB|CAPZRBAF600|ZUBR1|p600
Cytomap('CAPZB')('UBR4')

1p36.13

1p36.13

Type of geneprotein-codingprotein-coding
DescriptionF-actin-capping protein subunit betacapZ betacapping actin protein of muscle Z-line beta subunitcapping protein (actin filament) muscle Z-line, betaepididymis secretory sperm binding proteinE3 ubiquitin-protein ligase UBR4N-recognin-4RING-type E3 ubiquitin transferase UBR4retinoblastoma-associated factor 600-like proteinretinoblastoma-associated factor of 600 kDazinc finger UBR1-type protein 1
Modification date2020032020200313
UniProtAcc

P47756

.
Ensembl transtripts involved in fusion geneENST00000264202, ENST00000375142, 
ENST00000401084, ENST00000264203, 
ENST00000482808, ENST00000375144, 
ENST00000433834, 
Fusion gene scores* DoF score20 X 22 X 11=484014 X 16 X 7=1568
# samples 2916
** MAII scorelog2(29/4840*10)=-4.06088224214702
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(16/1568*10)=-3.29278174922785
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CAPZB [Title/Abstract] AND UBR4 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCAPZB(19811930)-UBR4(19415471), # samples:1
Anticipated loss of major functional domain due to fusion event.CAPZB-UBR4 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
CAPZB-UBR4 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
CAPZB-UBR4 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
CAPZB-UBR4 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneUBR4

GO:0006511

ubiquitin-dependent protein catabolic process

23932781


check buttonFusion gene breakpoints across CAPZB (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across UBR4 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4READTCGA-AH-6549CAPZBchr1

19811930

-UBR4chr1

19415471

-


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Fusion Gene ORF analysis for CAPZB-UBR4

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000264202ENST00000375218CAPZBchr1

19811930

-UBR4chr1

19415471

-
5CDS-intronENST00000264202ENST00000375224CAPZBchr1

19811930

-UBR4chr1

19415471

-
5CDS-intronENST00000264202ENST00000375225CAPZBchr1

19811930

-UBR4chr1

19415471

-
5CDS-intronENST00000264202ENST00000429347CAPZBchr1

19811930

-UBR4chr1

19415471

-
5CDS-intronENST00000264202ENST00000467272CAPZBchr1

19811930

-UBR4chr1

19415471

-
5CDS-intronENST00000264202ENST00000543981CAPZBchr1

19811930

-UBR4chr1

19415471

-
5CDS-intronENST00000375142ENST00000375218CAPZBchr1

19811930

-UBR4chr1

19415471

-
5CDS-intronENST00000375142ENST00000375224CAPZBchr1

19811930

-UBR4chr1

19415471

-
5CDS-intronENST00000375142ENST00000375225CAPZBchr1

19811930

-UBR4chr1

19415471

-
5CDS-intronENST00000375142ENST00000429347CAPZBchr1

19811930

-UBR4chr1

19415471

-
5CDS-intronENST00000375142ENST00000467272CAPZBchr1

19811930

-UBR4chr1

19415471

-
5CDS-intronENST00000375142ENST00000543981CAPZBchr1

19811930

-UBR4chr1

19415471

-
5CDS-intronENST00000401084ENST00000375218CAPZBchr1

19811930

-UBR4chr1

19415471

-
5CDS-intronENST00000401084ENST00000375224CAPZBchr1

19811930

-UBR4chr1

19415471

-
5CDS-intronENST00000401084ENST00000375225CAPZBchr1

19811930

-UBR4chr1

19415471

-
5CDS-intronENST00000401084ENST00000429347CAPZBchr1

19811930

-UBR4chr1

19415471

-
5CDS-intronENST00000401084ENST00000467272CAPZBchr1

19811930

-UBR4chr1

19415471

-
5CDS-intronENST00000401084ENST00000543981CAPZBchr1

19811930

-UBR4chr1

19415471

-
5UTR-3CDSENST00000264203ENST00000375217CAPZBchr1

19811930

-UBR4chr1

19415471

-
5UTR-3CDSENST00000264203ENST00000375226CAPZBchr1

19811930

-UBR4chr1

19415471

-
5UTR-3CDSENST00000264203ENST00000375254CAPZBchr1

19811930

-UBR4chr1

19415471

-
5UTR-3CDSENST00000264203ENST00000375267CAPZBchr1

19811930

-UBR4chr1

19415471

-
5UTR-3CDSENST00000482808ENST00000375217CAPZBchr1

19811930

-UBR4chr1

19415471

-
5UTR-3CDSENST00000482808ENST00000375226CAPZBchr1

19811930

-UBR4chr1

19415471

-
5UTR-3CDSENST00000482808ENST00000375254CAPZBchr1

19811930

-UBR4chr1

19415471

-
5UTR-3CDSENST00000482808ENST00000375267CAPZBchr1

19811930

-UBR4chr1

19415471

-
5UTR-intronENST00000264203ENST00000375218CAPZBchr1

19811930

-UBR4chr1

19415471

-
5UTR-intronENST00000264203ENST00000375224CAPZBchr1

19811930

-UBR4chr1

19415471

-
5UTR-intronENST00000264203ENST00000375225CAPZBchr1

19811930

-UBR4chr1

19415471

-
5UTR-intronENST00000264203ENST00000429347CAPZBchr1

19811930

-UBR4chr1

19415471

-
5UTR-intronENST00000264203ENST00000467272CAPZBchr1

19811930

-UBR4chr1

19415471

-
5UTR-intronENST00000264203ENST00000543981CAPZBchr1

19811930

-UBR4chr1

19415471

-
5UTR-intronENST00000482808ENST00000375218CAPZBchr1

19811930

-UBR4chr1

19415471

-
5UTR-intronENST00000482808ENST00000375224CAPZBchr1

19811930

-UBR4chr1

19415471

-
5UTR-intronENST00000482808ENST00000375225CAPZBchr1

19811930

-UBR4chr1

19415471

-
5UTR-intronENST00000482808ENST00000429347CAPZBchr1

19811930

-UBR4chr1

19415471

-
5UTR-intronENST00000482808ENST00000467272CAPZBchr1

19811930

-UBR4chr1

19415471

-
5UTR-intronENST00000482808ENST00000543981CAPZBchr1

19811930

-UBR4chr1

19415471

-
In-frameENST00000264202ENST00000375217CAPZBchr1

19811930

-UBR4chr1

19415471

-
In-frameENST00000264202ENST00000375226CAPZBchr1

19811930

-UBR4chr1

19415471

-
In-frameENST00000264202ENST00000375254CAPZBchr1

19811930

-UBR4chr1

19415471

-
In-frameENST00000264202ENST00000375267CAPZBchr1

19811930

-UBR4chr1

19415471

-
In-frameENST00000375142ENST00000375217CAPZBchr1

19811930

-UBR4chr1

19415471

-
In-frameENST00000375142ENST00000375226CAPZBchr1

19811930

-UBR4chr1

19415471

-
In-frameENST00000375142ENST00000375254CAPZBchr1

19811930

-UBR4chr1

19415471

-
In-frameENST00000375142ENST00000375267CAPZBchr1

19811930

-UBR4chr1

19415471

-
In-frameENST00000401084ENST00000375217CAPZBchr1

19811930

-UBR4chr1

19415471

-
In-frameENST00000401084ENST00000375226CAPZBchr1

19811930

-UBR4chr1

19415471

-
In-frameENST00000401084ENST00000375254CAPZBchr1

19811930

-UBR4chr1

19415471

-
In-frameENST00000401084ENST00000375267CAPZBchr1

19811930

-UBR4chr1

19415471

-
intron-3CDSENST00000375144ENST00000375217CAPZBchr1

19811930

-UBR4chr1

19415471

-
intron-3CDSENST00000375144ENST00000375226CAPZBchr1

19811930

-UBR4chr1

19415471

-
intron-3CDSENST00000375144ENST00000375254CAPZBchr1

19811930

-UBR4chr1

19415471

-
intron-3CDSENST00000375144ENST00000375267CAPZBchr1

19811930

-UBR4chr1

19415471

-
intron-3CDSENST00000433834ENST00000375217CAPZBchr1

19811930

-UBR4chr1

19415471

-
intron-3CDSENST00000433834ENST00000375226CAPZBchr1

19811930

-UBR4chr1

19415471

-
intron-3CDSENST00000433834ENST00000375254CAPZBchr1

19811930

-UBR4chr1

19415471

-
intron-3CDSENST00000433834ENST00000375267CAPZBchr1

19811930

-UBR4chr1

19415471

-
intron-intronENST00000375144ENST00000375218CAPZBchr1

19811930

-UBR4chr1

19415471

-
intron-intronENST00000375144ENST00000375224CAPZBchr1

19811930

-UBR4chr1

19415471

-
intron-intronENST00000375144ENST00000375225CAPZBchr1

19811930

-UBR4chr1

19415471

-
intron-intronENST00000375144ENST00000429347CAPZBchr1

19811930

-UBR4chr1

19415471

-
intron-intronENST00000375144ENST00000467272CAPZBchr1

19811930

-UBR4chr1

19415471

-
intron-intronENST00000375144ENST00000543981CAPZBchr1

19811930

-UBR4chr1

19415471

-
intron-intronENST00000433834ENST00000375218CAPZBchr1

19811930

-UBR4chr1

19415471

-
intron-intronENST00000433834ENST00000375224CAPZBchr1

19811930

-UBR4chr1

19415471

-
intron-intronENST00000433834ENST00000375225CAPZBchr1

19811930

-UBR4chr1

19415471

-
intron-intronENST00000433834ENST00000429347CAPZBchr1

19811930

-UBR4chr1

19415471

-
intron-intronENST00000433834ENST00000467272CAPZBchr1

19811930

-UBR4chr1

19415471

-
intron-intronENST00000433834ENST00000543981CAPZBchr1

19811930

-UBR4chr1

19415471

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)
BP loci
(transcript)
Predicted start
(transcript)
Predicted stop
(transcript)
Seq length
(amino acids)
ENST00000401084CAPZBchr119811930-ENST00000375217UBR4chr119415471-18041371341477447
ENST00000401084CAPZBchr119811930-ENST00000375226UBR4chr119415471-18041371341477447
ENST00000401084CAPZBchr119811930-ENST00000375267UBR4chr119415471-18671371341540468
ENST00000401084CAPZBchr119811930-ENST00000375254UBR4chr119415471-18041371341477447
ENST00000375142CAPZBchr119811930-ENST00000375217UBR4chr119415471-171750471390447
ENST00000375142CAPZBchr119811930-ENST00000375226UBR4chr119415471-171750471390447
ENST00000375142CAPZBchr119811930-ENST00000375267UBR4chr119415471-178050471453468
ENST00000375142CAPZBchr119811930-ENST00000375254UBR4chr119415471-171750471390447
ENST00000264202CAPZBchr119811930-ENST00000375217UBR4chr119415471-171952491392447
ENST00000264202CAPZBchr119811930-ENST00000375226UBR4chr119415471-171952491392447
ENST00000264202CAPZBchr119811930-ENST00000375267UBR4chr119415471-178252491455468
ENST00000264202CAPZBchr119811930-ENST00000375254UBR4chr119415471-171952491392447

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000401084ENST00000375217CAPZBchr119811930-UBR4chr119415471-0.0064442390.9935557
ENST00000401084ENST00000375226CAPZBchr119811930-UBR4chr119415471-0.0064442390.9935557
ENST00000401084ENST00000375267CAPZBchr119811930-UBR4chr119415471-0.006078210.99392176
ENST00000401084ENST00000375254CAPZBchr119811930-UBR4chr119415471-0.0064442390.9935557
ENST00000375142ENST00000375217CAPZBchr119811930-UBR4chr119415471-0.0078562910.99214375
ENST00000375142ENST00000375226CAPZBchr119811930-UBR4chr119415471-0.0078562910.99214375
ENST00000375142ENST00000375267CAPZBchr119811930-UBR4chr119415471-0.0073400320.99266
ENST00000375142ENST00000375254CAPZBchr119811930-UBR4chr119415471-0.0078562910.99214375
ENST00000264202ENST00000375217CAPZBchr119811930-UBR4chr119415471-0.0076872250.9923127
ENST00000264202ENST00000375226CAPZBchr119811930-UBR4chr119415471-0.0076872250.9923127
ENST00000264202ENST00000375267CAPZBchr119811930-UBR4chr119415471-0.0071822040.99281776
ENST00000264202ENST00000375254CAPZBchr119811930-UBR4chr119415471-0.0076872250.9923127

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Fusion Genomic Features for CAPZB-UBR4


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for CAPZB-UBR4


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr1:19811930/chr1:19415471)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
CAPZB

P47756

.
FUNCTION: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. Plays a role in the regulation of cell morphology and cytoskeletal organization. {ECO:0000269|PubMed:21834987}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneUBR4chr1:19811930chr1:19415471ENST00000375218052728_27380213.0Compositional biasNote=Poly-Asp
TgeneUBR4chr1:19811930chr1:19415471ENST00000375218053339_33700213.0Compositional biasNote=Ser-rich
TgeneUBR4chr1:19811930chr1:19415471ENST0000037521805608_6310213.0Compositional biasNote=Pro-rich
TgeneUBR4chr1:19811930chr1:19415471ENST00000375218059_150213.0Compositional biasNote=Poly-Ala
TgeneUBR4chr1:19811930chr1:19415471ENST0000037521805850_8700213.0TransmembraneHelical
TgeneUBR4chr1:19811930chr1:19415471ENST0000037521805993_10130213.0TransmembraneHelical
TgeneUBR4chr1:19811930chr1:19415471ENST00000375218051656_17290213.0Zinc fingerUBR-type

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneUBR4chr1:19811930chr1:19415471ENST00000375217961062728_273847305177.0Compositional biasNote=Poly-Asp
TgeneUBR4chr1:19811930chr1:19415471ENST00000375217961063339_337047305177.0Compositional biasNote=Ser-rich
TgeneUBR4chr1:19811930chr1:19415471ENST0000037521796106608_63147305177.0Compositional biasNote=Pro-rich
TgeneUBR4chr1:19811930chr1:19415471ENST00000375217961069_1547305177.0Compositional biasNote=Poly-Ala
TgeneUBR4chr1:19811930chr1:19415471ENST00000375226961062728_273847135160.0Compositional biasNote=Poly-Asp
TgeneUBR4chr1:19811930chr1:19415471ENST00000375226961063339_337047135160.0Compositional biasNote=Ser-rich
TgeneUBR4chr1:19811930chr1:19415471ENST0000037522696106608_63147135160.0Compositional biasNote=Pro-rich
TgeneUBR4chr1:19811930chr1:19415471ENST00000375226961069_1547135160.0Compositional biasNote=Poly-Ala
TgeneUBR4chr1:19811930chr1:19415471ENST00000375254961062728_273847375184.0Compositional biasNote=Poly-Asp
TgeneUBR4chr1:19811930chr1:19415471ENST00000375254961063339_337047375184.0Compositional biasNote=Ser-rich
TgeneUBR4chr1:19811930chr1:19415471ENST0000037525496106608_63147375184.0Compositional biasNote=Pro-rich
TgeneUBR4chr1:19811930chr1:19415471ENST00000375254961069_1547375184.0Compositional biasNote=Poly-Ala
TgeneUBR4chr1:19811930chr1:19415471ENST00000375267961072728_273847375205.0Compositional biasNote=Poly-Asp
TgeneUBR4chr1:19811930chr1:19415471ENST00000375267961073339_337047375205.0Compositional biasNote=Ser-rich
TgeneUBR4chr1:19811930chr1:19415471ENST0000037526796107608_63147375205.0Compositional biasNote=Pro-rich
TgeneUBR4chr1:19811930chr1:19415471ENST00000375267961079_1547375205.0Compositional biasNote=Poly-Ala
TgeneUBR4chr1:19811930chr1:19415471ENST0000037521796106850_87047305177.0TransmembraneHelical
TgeneUBR4chr1:19811930chr1:19415471ENST0000037521796106993_101347305177.0TransmembraneHelical
TgeneUBR4chr1:19811930chr1:19415471ENST0000037522696106850_87047135160.0TransmembraneHelical
TgeneUBR4chr1:19811930chr1:19415471ENST0000037522696106993_101347135160.0TransmembraneHelical
TgeneUBR4chr1:19811930chr1:19415471ENST0000037525496106850_87047375184.0TransmembraneHelical
TgeneUBR4chr1:19811930chr1:19415471ENST0000037525496106993_101347375184.0TransmembraneHelical
TgeneUBR4chr1:19811930chr1:19415471ENST0000037526796107850_87047375205.0TransmembraneHelical
TgeneUBR4chr1:19811930chr1:19415471ENST0000037526796107993_101347375205.0TransmembraneHelical
TgeneUBR4chr1:19811930chr1:19415471ENST00000375217961061656_172947305177.0Zinc fingerUBR-type
TgeneUBR4chr1:19811930chr1:19415471ENST00000375226961061656_172947135160.0Zinc fingerUBR-type
TgeneUBR4chr1:19811930chr1:19415471ENST00000375254961061656_172947375184.0Zinc fingerUBR-type
TgeneUBR4chr1:19811930chr1:19415471ENST00000375267961071656_172947375205.0Zinc fingerUBR-type


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Fusion Gene Sequence for CAPZB-UBR4


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>13016_13016_1_CAPZB-UBR4_CAPZB_chr1_19811930_ENST00000264202_UBR4_chr1_19415471_ENST00000375217_length(transcript)=1719nt_BP=52nt
GGGGAGAGCCACTGACGCCGGGACCGGGACCGCCGCCGCCGCCGCCACCATGGTTCTGATTGGAACTGATTCCATCCCGAACCTGCATAA
GCTGGAGCAGGTGTCCAGTGATGAGGGCATTGGGACCTTGGCAGAGAACCTGCTGGAAGCCCTGCGGGAACACCCTGACGTAAACAAGAA
GATTGACGCAGCCCGCAGGGAGACCCGGGCAGAGAAGAAGCGCATGGCCATGGCAATGAGGCAGAAGGCCCTGGGCACCCTGGGCATGAC
GACAAATGAAAAGGGCCAGGTCGTGACCAAGACAGCACTCCTGAAGCAGATGGAAGAGCTGATCGAGGAGCCTGGCCTCACGTGCTGCAT
CTGCAGGGAGGGATACAAGTTCCAGCCCACAAAGGTCCTGGGCATTTATACCTTCACGAAGCGGGTAGCCTTGGAGGAGATGGAGAATAA
GCCCCGGAAACAGCAGGGCTACAGCACCGTGTCCCACTTCAACATTGTGCACTACGACTGCCATCTGGCTGCCGTCAGGTTGGCTCGAGG
CCGGGAAGAGTGGGAGAGTGCCGCCCTGCAGAATGCCAACACCAAGTGCAACGGGCTCCTTCCGGTCTGGGGACCTCATGTCCCTGAATC
AGCTTTTGCCACTTGCTTGGCAAGACACAACACTTACCTCCAGGAATGTACAGGCCAGCGGGAGCCCACGTATCAGCTCAACATCCATGA
CATCAAACTGCTCTTCCTGCGCTTCGCCATGGAGCAGTCGTTCAGCGCAGACACTGGCGGGGGCGGCCGGGAGAGCAACATCCACCTGAT
CCCGTACATCATTCACACTGTGCTTTACGTCCTGAACACAACCCGAGCAACTTCCCGAGAAGAGAAGAACCTCCAAGGCTTTCTGGAACA
GCCCAAGGAGAAGTGGGTGGAGAGTGCCTTTGAAGTGGACGGGCCCTACTATTTCACAGTCTTGGCCCTTCACATCCTGCCCCCTGAGCA
GTGGAGAGCCACACGTGTGGAAATCTTGCGGAGGCTGTTGGTGACCTCGCAGGCTCGGGCAGTGGCTCCAGGTGGAGCCACCAGGCTGAC
AGATAAGGCAGTGAAGGACTATTCCGCTTACCGTTCTTCCCTTCTCTTTTGGGCCCTCGTCGATCTCATTTACAACATGTTTAAGAAGGT
GCCTACCAGTAACACAGAGGGAGGCTGGTCCTGCTCTCTCGCTGAGTACATCCGCCACAACGACATGCCCATCTACGAAGCTGCCGACAA
AGCCCTGAAAACCTTCCAGGAGGAGTTCATGCCAGTGGAGACCTTCTCAGAGTTCCTCGATGTGGCCGGTCTTTTATCAGAAATCACCGA
TCCAGAGAGCTTCCTGAAGGACCTGTTGAACTCAGTCCCCTGACCACCACACAGCAGCTGCGGCGGCGAAGACGAAGCTGGCTTGCCTTC
CACCCTCTGTTCTCCCTCCTTGTGCATTAAGTTCCCTCCGCGGGATGCTGCATTGTTACCCCGCCCTCCCCTCTCTCATTTTTCTTGGTG
TGGCTTGGGGTTTTTAGGCTTCCTGTTTTATCTCGTGTGTGTGGTGCACCAGCTATGAGGTTGTCTGTAACCCAAGCCATCAAAGGGCCT
GTACATACCTAGGAGCCATGAGTTGTCCCGGCCAGCTTCATACTTGAGTGTGCACATCTTGAGAAATAAACAAGTGACTTAACACACATT

>13016_13016_1_CAPZB-UBR4_CAPZB_chr1_19811930_ENST00000264202_UBR4_chr1_19415471_ENST00000375217_length(amino acids)=447AA_BP=1
MVLIGTDSIPNLHKLEQVSSDEGIGTLAENLLEALREHPDVNKKIDAARRETRAEKKRMAMAMRQKALGTLGMTTNEKGQVVTKTALLKQ
MEELIEEPGLTCCICREGYKFQPTKVLGIYTFTKRVALEEMENKPRKQQGYSTVSHFNIVHYDCHLAAVRLARGREEWESAALQNANTKC
NGLLPVWGPHVPESAFATCLARHNTYLQECTGQREPTYQLNIHDIKLLFLRFAMEQSFSADTGGGGRESNIHLIPYIIHTVLYVLNTTRA
TSREEKNLQGFLEQPKEKWVESAFEVDGPYYFTVLALHILPPEQWRATRVEILRRLLVTSQARAVAPGGATRLTDKAVKDYSAYRSSLLF

--------------------------------------------------------------
>13016_13016_2_CAPZB-UBR4_CAPZB_chr1_19811930_ENST00000264202_UBR4_chr1_19415471_ENST00000375226_length(transcript)=1719nt_BP=52nt
GGGGAGAGCCACTGACGCCGGGACCGGGACCGCCGCCGCCGCCGCCACCATGGTTCTGATTGGAACTGATTCCATCCCGAACCTGCATAA
GCTGGAGCAGGTGTCCAGTGATGAGGGCATTGGGACCTTGGCAGAGAACCTGCTGGAAGCCCTGCGGGAACACCCTGACGTAAACAAGAA
GATTGACGCAGCCCGCAGGGAGACCCGGGCAGAGAAGAAGCGCATGGCCATGGCAATGAGGCAGAAGGCCCTGGGCACCCTGGGCATGAC
GACAAATGAAAAGGGCCAGGTCGTGACCAAGACAGCACTCCTGAAGCAGATGGAAGAGCTGATCGAGGAGCCTGGCCTCACGTGCTGCAT
CTGCAGGGAGGGATACAAGTTCCAGCCCACAAAGGTCCTGGGCATTTATACCTTCACGAAGCGGGTAGCCTTGGAGGAGATGGAGAATAA
GCCCCGGAAACAGCAGGGCTACAGCACCGTGTCCCACTTCAACATTGTGCACTACGACTGCCATCTGGCTGCCGTCAGGTTGGCTCGAGG
CCGGGAAGAGTGGGAGAGTGCCGCCCTGCAGAATGCCAACACCAAGTGCAACGGGCTCCTTCCGGTCTGGGGACCTCATGTCCCTGAATC
AGCTTTTGCCACTTGCTTGGCAAGACACAACACTTACCTCCAGGAATGTACAGGCCAGCGGGAGCCCACGTATCAGCTCAACATCCATGA
CATCAAACTGCTCTTCCTGCGCTTCGCCATGGAGCAGTCGTTCAGCGCAGACACTGGCGGGGGCGGCCGGGAGAGCAACATCCACCTGAT
CCCGTACATCATTCACACTGTGCTTTACGTCCTGAACACAACCCGAGCAACTTCCCGAGAAGAGAAGAACCTCCAAGGCTTTCTGGAACA
GCCCAAGGAGAAGTGGGTGGAGAGTGCCTTTGAAGTGGACGGGCCCTACTATTTCACAGTCTTGGCCCTTCACATCCTGCCCCCTGAGCA
GTGGAGAGCCACACGTGTGGAAATCTTGCGGAGGCTGTTGGTGACCTCGCAGGCTCGGGCAGTGGCTCCAGGTGGAGCCACCAGGCTGAC
AGATAAGGCAGTGAAGGACTATTCCGCTTACCGTTCTTCCCTTCTCTTTTGGGCCCTCGTCGATCTCATTTACAACATGTTTAAGAAGGT
GCCTACCAGTAACACAGAGGGAGGCTGGTCCTGCTCTCTCGCTGAGTACATCCGCCACAACGACATGCCCATCTACGAAGCTGCCGACAA
AGCCCTGAAAACCTTCCAGGAGGAGTTCATGCCAGTGGAGACCTTCTCAGAGTTCCTCGATGTGGCCGGTCTTTTATCAGAAATCACCGA
TCCAGAGAGCTTCCTGAAGGACCTGTTGAACTCAGTCCCCTGACCACCACACAGCAGCTGCGGCGGCGAAGACGAAGCTGGCTTGCCTTC
CACCCTCTGTTCTCCCTCCTTGTGCATTAAGTTCCCTCCGCGGGATGCTGCATTGTTACCCCGCCCTCCCCTCTCTCATTTTTCTTGGTG
TGGCTTGGGGTTTTTAGGCTTCCTGTTTTATCTCGTGTGTGTGGTGCACCAGCTATGAGGTTGTCTGTAACCCAAGCCATCAAAGGGCCT
GTACATACCTAGGAGCCATGAGTTGTCCCGGCCAGCTTCATACTTGAGTGTGCACATCTTGAGAAATAAACAAGTGACTTAACACACATT

>13016_13016_2_CAPZB-UBR4_CAPZB_chr1_19811930_ENST00000264202_UBR4_chr1_19415471_ENST00000375226_length(amino acids)=447AA_BP=1
MVLIGTDSIPNLHKLEQVSSDEGIGTLAENLLEALREHPDVNKKIDAARRETRAEKKRMAMAMRQKALGTLGMTTNEKGQVVTKTALLKQ
MEELIEEPGLTCCICREGYKFQPTKVLGIYTFTKRVALEEMENKPRKQQGYSTVSHFNIVHYDCHLAAVRLARGREEWESAALQNANTKC
NGLLPVWGPHVPESAFATCLARHNTYLQECTGQREPTYQLNIHDIKLLFLRFAMEQSFSADTGGGGRESNIHLIPYIIHTVLYVLNTTRA
TSREEKNLQGFLEQPKEKWVESAFEVDGPYYFTVLALHILPPEQWRATRVEILRRLLVTSQARAVAPGGATRLTDKAVKDYSAYRSSLLF

--------------------------------------------------------------
>13016_13016_3_CAPZB-UBR4_CAPZB_chr1_19811930_ENST00000264202_UBR4_chr1_19415471_ENST00000375254_length(transcript)=1719nt_BP=52nt
GGGGAGAGCCACTGACGCCGGGACCGGGACCGCCGCCGCCGCCGCCACCATGGTTCTGATTGGAACTGATTCCATCCCGAACCTGCATAA
GCTGGAGCAGGTGTCCAGTGATGAGGGCATTGGGACCTTGGCAGAGAACCTGCTGGAAGCCCTGCGGGAACACCCTGACGTAAACAAGAA
GATTGACGCAGCCCGCAGGGAGACCCGGGCAGAGAAGAAGCGCATGGCCATGGCAATGAGGCAGAAGGCCCTGGGCACCCTGGGCATGAC
GACAAATGAAAAGGGCCAGGTCGTGACCAAGACAGCACTCCTGAAGCAGATGGAAGAGCTGATCGAGGAGCCTGGCCTCACGTGCTGCAT
CTGCAGGGAGGGATACAAGTTCCAGCCCACAAAGGTCCTGGGCATTTATACCTTCACGAAGCGGGTAGCCTTGGAGGAGATGGAGAATAA
GCCCCGGAAACAGCAGGGCTACAGCACCGTGTCCCACTTCAACATTGTGCACTACGACTGCCATCTGGCTGCCGTCAGGTTGGCTCGAGG
CCGGGAAGAGTGGGAGAGTGCCGCCCTGCAGAATGCCAACACCAAGTGCAACGGGCTCCTTCCGGTCTGGGGACCTCATGTCCCTGAATC
AGCTTTTGCCACTTGCTTGGCAAGACACAACACTTACCTCCAGGAATGTACAGGCCAGCGGGAGCCCACGTATCAGCTCAACATCCATGA
CATCAAACTGCTCTTCCTGCGCTTCGCCATGGAGCAGTCGTTCAGCGCAGACACTGGCGGGGGCGGCCGGGAGAGCAACATCCACCTGAT
CCCGTACATCATTCACACTGTGCTTTACGTCCTGAACACAACCCGAGCAACTTCCCGAGAAGAGAAGAACCTCCAAGGCTTTCTGGAACA
GCCCAAGGAGAAGTGGGTGGAGAGTGCCTTTGAAGTGGACGGGCCCTACTATTTCACAGTCTTGGCCCTTCACATCCTGCCCCCTGAGCA
GTGGAGAGCCACACGTGTGGAAATCTTGCGGAGGCTGTTGGTGACCTCGCAGGCTCGGGCAGTGGCTCCAGGTGGAGCCACCAGGCTGAC
AGATAAGGCAGTGAAGGACTATTCCGCTTACCGTTCTTCCCTTCTCTTTTGGGCCCTCGTCGATCTCATTTACAACATGTTTAAGAAGGT
GCCTACCAGTAACACAGAGGGAGGCTGGTCCTGCTCTCTCGCTGAGTACATCCGCCACAACGACATGCCCATCTACGAAGCTGCCGACAA
AGCCCTGAAAACCTTCCAGGAGGAGTTCATGCCAGTGGAGACCTTCTCAGAGTTCCTCGATGTGGCCGGTCTTTTATCAGAAATCACCGA
TCCAGAGAGCTTCCTGAAGGACCTGTTGAACTCAGTCCCCTGACCACCACACAGCAGCTGCGGCGGCGAAGACGAAGCTGGCTTGCCTTC
CACCCTCTGTTCTCCCTCCTTGTGCATTAAGTTCCCTCCGCGGGATGCTGCATTGTTACCCCGCCCTCCCCTCTCTCATTTTTCTTGGTG
TGGCTTGGGGTTTTTAGGCTTCCTGTTTTATCTCGTGTGTGTGGTGCACCAGCTATGAGGTTGTCTGTAACCCAAGCCATCAAAGGGCCT
GTACATACCTAGGAGCCATGAGTTGTCCCGGCCAGCTTCATACTTGAGTGTGCACATCTTGAGAAATAAACAAGTGACTTAACACACATT

>13016_13016_3_CAPZB-UBR4_CAPZB_chr1_19811930_ENST00000264202_UBR4_chr1_19415471_ENST00000375254_length(amino acids)=447AA_BP=1
MVLIGTDSIPNLHKLEQVSSDEGIGTLAENLLEALREHPDVNKKIDAARRETRAEKKRMAMAMRQKALGTLGMTTNEKGQVVTKTALLKQ
MEELIEEPGLTCCICREGYKFQPTKVLGIYTFTKRVALEEMENKPRKQQGYSTVSHFNIVHYDCHLAAVRLARGREEWESAALQNANTKC
NGLLPVWGPHVPESAFATCLARHNTYLQECTGQREPTYQLNIHDIKLLFLRFAMEQSFSADTGGGGRESNIHLIPYIIHTVLYVLNTTRA
TSREEKNLQGFLEQPKEKWVESAFEVDGPYYFTVLALHILPPEQWRATRVEILRRLLVTSQARAVAPGGATRLTDKAVKDYSAYRSSLLF

--------------------------------------------------------------
>13016_13016_4_CAPZB-UBR4_CAPZB_chr1_19811930_ENST00000264202_UBR4_chr1_19415471_ENST00000375267_length(transcript)=1782nt_BP=52nt
GGGGAGAGCCACTGACGCCGGGACCGGGACCGCCGCCGCCGCCGCCACCATGGTTCTGATTGGAACTGATTCCATCCCGAACCTGCATAA
GCTGGAGCAGGTGTCCAGTGATGAGGGCATTGGGACCTTGGCAGAGAACCTGCTGGAAGCCCTGCGGGAACACCCTGACGTAAACAAGAA
GATTGACGCAGCCCGCAGGGAGACCCGGGCAGAGAAGAAGCGCATGGCCATGGCAATGAGGCAGAAGGCCCTGGGCACCCTGGGCATGAC
GACAAATGAAAAGGGCCAGGTCGTGACCAAGACAGCACTCCTGAAGCAGATGGAAGAGCTGATCGAGGAGCCTGGCCTCACGTGCTGCAT
CTGCAGGGAGGGATACAAGTTCCAGCCCACAAAGGTCCTGGGCATTTATACCTTCACGAAGCGGGTAGCCTTGGAGGAGATGGAGAATAA
GCCCCGGAAACAGCAGGGCTACAGCACCGTGTCCCACTTCAACATTGTGCACTACGACTGCCATCTGGCTGCCGTCAGGTTGGCTCGAGG
CCGGGAAGAGTGGGAGAGTGCCGCCCTGCAGAATGCCAACACCAAGTGCAACGGGCTCCTTCCGGTCTGGGGACCTCATGTCCCTGAATC
AGCTTTTGCCACTTGCTTGGCAAGACACAACACTTACCTCCAGGAATGTACAGGCCAGCGGGAGCCCACGTATCAGCTCAACATCCATGA
CATCAAACTGCTCTTCCTGCGCTTCGCCATGGAGCAGTCGTTCAGCGCAGACACTGGCGGGGGCGGCCGGGAGAGCAACATCCACCTGAT
CCCGTACATCATTCACACTGTGCTTTACGTCCTGAACACAACCCGAGCAACTTCCCGAGAAGAGAAGAACCTCCAAGGCTTTCTGGAACA
GCCCAAGGAGAAGTGGGTGGAGAGTGCCTTTGAAGTGGACGGGCCCTACTATTTCACAGTCTTGGCCCTTCACATCCTGCCCCCTGAGCA
GTGGAGAGCCACACGTGTGGAAATCTTGCGGAGGCTGTTGGTGACCTCGCAGGCTCGGGCAGTGGCTCCAGGTGGAGCCACCAGGCTGAC
AGATAAGGCAGTGAAGGACTATTCCGCTTACCGTTCTTCCCTTCTCTTTTGGGCCCTCGTCGATCTCATTTACAACATGTTTAAGAAACA
AACAACCCCAACTGTGGGAGGGATTGACACTGGCAGCCTGGAGCCTTGTGTCTGTGAGAAGGTGCCTACCAGTAACACAGAGGGAGGCTG
GTCCTGCTCTCTCGCTGAGTACATCCGCCACAACGACATGCCCATCTACGAAGCTGCCGACAAAGCCCTGAAAACCTTCCAGGAGGAGTT
CATGCCAGTGGAGACCTTCTCAGAGTTCCTCGATGTGGCCGGTCTTTTATCAGAAATCACCGATCCAGAGAGCTTCCTGAAGGACCTGTT
GAACTCAGTCCCCTGACCACCACACAGCAGCTGCGGCGGCGAAGACGAAGCTGGCTTGCCTTCCACCCTCTGTTCTCCCTCCTTGTGCAT
TAAGTTCCCTCCGCGGGATGCTGCATTGTTACCCCGCCCTCCCCTCTCTCATTTTTCTTGGTGTGGCTTGGGGTTTTTAGGCTTCCTGTT
TTATCTCGTGTGTGTGGTGCACCAGCTATGAGGTTGTCTGTAACCCAAGCCATCAAAGGGCCTGTACATACCTAGGAGCCATGAGTTGTC

>13016_13016_4_CAPZB-UBR4_CAPZB_chr1_19811930_ENST00000264202_UBR4_chr1_19415471_ENST00000375267_length(amino acids)=468AA_BP=1
MVLIGTDSIPNLHKLEQVSSDEGIGTLAENLLEALREHPDVNKKIDAARRETRAEKKRMAMAMRQKALGTLGMTTNEKGQVVTKTALLKQ
MEELIEEPGLTCCICREGYKFQPTKVLGIYTFTKRVALEEMENKPRKQQGYSTVSHFNIVHYDCHLAAVRLARGREEWESAALQNANTKC
NGLLPVWGPHVPESAFATCLARHNTYLQECTGQREPTYQLNIHDIKLLFLRFAMEQSFSADTGGGGRESNIHLIPYIIHTVLYVLNTTRA
TSREEKNLQGFLEQPKEKWVESAFEVDGPYYFTVLALHILPPEQWRATRVEILRRLLVTSQARAVAPGGATRLTDKAVKDYSAYRSSLLF
WALVDLIYNMFKKQTTPTVGGIDTGSLEPCVCEKVPTSNTEGGWSCSLAEYIRHNDMPIYEAADKALKTFQEEFMPVETFSEFLDVAGLL

--------------------------------------------------------------
>13016_13016_5_CAPZB-UBR4_CAPZB_chr1_19811930_ENST00000375142_UBR4_chr1_19415471_ENST00000375217_length(transcript)=1717nt_BP=50nt
GGAGAGCCACTGACGCCGGGACCGGGACCGCCGCCGCCGCCGCCACCATGGTTCTGATTGGAACTGATTCCATCCCGAACCTGCATAAGC
TGGAGCAGGTGTCCAGTGATGAGGGCATTGGGACCTTGGCAGAGAACCTGCTGGAAGCCCTGCGGGAACACCCTGACGTAAACAAGAAGA
TTGACGCAGCCCGCAGGGAGACCCGGGCAGAGAAGAAGCGCATGGCCATGGCAATGAGGCAGAAGGCCCTGGGCACCCTGGGCATGACGA
CAAATGAAAAGGGCCAGGTCGTGACCAAGACAGCACTCCTGAAGCAGATGGAAGAGCTGATCGAGGAGCCTGGCCTCACGTGCTGCATCT
GCAGGGAGGGATACAAGTTCCAGCCCACAAAGGTCCTGGGCATTTATACCTTCACGAAGCGGGTAGCCTTGGAGGAGATGGAGAATAAGC
CCCGGAAACAGCAGGGCTACAGCACCGTGTCCCACTTCAACATTGTGCACTACGACTGCCATCTGGCTGCCGTCAGGTTGGCTCGAGGCC
GGGAAGAGTGGGAGAGTGCCGCCCTGCAGAATGCCAACACCAAGTGCAACGGGCTCCTTCCGGTCTGGGGACCTCATGTCCCTGAATCAG
CTTTTGCCACTTGCTTGGCAAGACACAACACTTACCTCCAGGAATGTACAGGCCAGCGGGAGCCCACGTATCAGCTCAACATCCATGACA
TCAAACTGCTCTTCCTGCGCTTCGCCATGGAGCAGTCGTTCAGCGCAGACACTGGCGGGGGCGGCCGGGAGAGCAACATCCACCTGATCC
CGTACATCATTCACACTGTGCTTTACGTCCTGAACACAACCCGAGCAACTTCCCGAGAAGAGAAGAACCTCCAAGGCTTTCTGGAACAGC
CCAAGGAGAAGTGGGTGGAGAGTGCCTTTGAAGTGGACGGGCCCTACTATTTCACAGTCTTGGCCCTTCACATCCTGCCCCCTGAGCAGT
GGAGAGCCACACGTGTGGAAATCTTGCGGAGGCTGTTGGTGACCTCGCAGGCTCGGGCAGTGGCTCCAGGTGGAGCCACCAGGCTGACAG
ATAAGGCAGTGAAGGACTATTCCGCTTACCGTTCTTCCCTTCTCTTTTGGGCCCTCGTCGATCTCATTTACAACATGTTTAAGAAGGTGC
CTACCAGTAACACAGAGGGAGGCTGGTCCTGCTCTCTCGCTGAGTACATCCGCCACAACGACATGCCCATCTACGAAGCTGCCGACAAAG
CCCTGAAAACCTTCCAGGAGGAGTTCATGCCAGTGGAGACCTTCTCAGAGTTCCTCGATGTGGCCGGTCTTTTATCAGAAATCACCGATC
CAGAGAGCTTCCTGAAGGACCTGTTGAACTCAGTCCCCTGACCACCACACAGCAGCTGCGGCGGCGAAGACGAAGCTGGCTTGCCTTCCA
CCCTCTGTTCTCCCTCCTTGTGCATTAAGTTCCCTCCGCGGGATGCTGCATTGTTACCCCGCCCTCCCCTCTCTCATTTTTCTTGGTGTG
GCTTGGGGTTTTTAGGCTTCCTGTTTTATCTCGTGTGTGTGGTGCACCAGCTATGAGGTTGTCTGTAACCCAAGCCATCAAAGGGCCTGT
ACATACCTAGGAGCCATGAGTTGTCCCGGCCAGCTTCATACTTGAGTGTGCACATCTTGAGAAATAAACAAGTGACTTAACACACATTGA

>13016_13016_5_CAPZB-UBR4_CAPZB_chr1_19811930_ENST00000375142_UBR4_chr1_19415471_ENST00000375217_length(amino acids)=447AA_BP=1
MVLIGTDSIPNLHKLEQVSSDEGIGTLAENLLEALREHPDVNKKIDAARRETRAEKKRMAMAMRQKALGTLGMTTNEKGQVVTKTALLKQ
MEELIEEPGLTCCICREGYKFQPTKVLGIYTFTKRVALEEMENKPRKQQGYSTVSHFNIVHYDCHLAAVRLARGREEWESAALQNANTKC
NGLLPVWGPHVPESAFATCLARHNTYLQECTGQREPTYQLNIHDIKLLFLRFAMEQSFSADTGGGGRESNIHLIPYIIHTVLYVLNTTRA
TSREEKNLQGFLEQPKEKWVESAFEVDGPYYFTVLALHILPPEQWRATRVEILRRLLVTSQARAVAPGGATRLTDKAVKDYSAYRSSLLF

--------------------------------------------------------------
>13016_13016_6_CAPZB-UBR4_CAPZB_chr1_19811930_ENST00000375142_UBR4_chr1_19415471_ENST00000375226_length(transcript)=1717nt_BP=50nt
GGAGAGCCACTGACGCCGGGACCGGGACCGCCGCCGCCGCCGCCACCATGGTTCTGATTGGAACTGATTCCATCCCGAACCTGCATAAGC
TGGAGCAGGTGTCCAGTGATGAGGGCATTGGGACCTTGGCAGAGAACCTGCTGGAAGCCCTGCGGGAACACCCTGACGTAAACAAGAAGA
TTGACGCAGCCCGCAGGGAGACCCGGGCAGAGAAGAAGCGCATGGCCATGGCAATGAGGCAGAAGGCCCTGGGCACCCTGGGCATGACGA
CAAATGAAAAGGGCCAGGTCGTGACCAAGACAGCACTCCTGAAGCAGATGGAAGAGCTGATCGAGGAGCCTGGCCTCACGTGCTGCATCT
GCAGGGAGGGATACAAGTTCCAGCCCACAAAGGTCCTGGGCATTTATACCTTCACGAAGCGGGTAGCCTTGGAGGAGATGGAGAATAAGC
CCCGGAAACAGCAGGGCTACAGCACCGTGTCCCACTTCAACATTGTGCACTACGACTGCCATCTGGCTGCCGTCAGGTTGGCTCGAGGCC
GGGAAGAGTGGGAGAGTGCCGCCCTGCAGAATGCCAACACCAAGTGCAACGGGCTCCTTCCGGTCTGGGGACCTCATGTCCCTGAATCAG
CTTTTGCCACTTGCTTGGCAAGACACAACACTTACCTCCAGGAATGTACAGGCCAGCGGGAGCCCACGTATCAGCTCAACATCCATGACA
TCAAACTGCTCTTCCTGCGCTTCGCCATGGAGCAGTCGTTCAGCGCAGACACTGGCGGGGGCGGCCGGGAGAGCAACATCCACCTGATCC
CGTACATCATTCACACTGTGCTTTACGTCCTGAACACAACCCGAGCAACTTCCCGAGAAGAGAAGAACCTCCAAGGCTTTCTGGAACAGC
CCAAGGAGAAGTGGGTGGAGAGTGCCTTTGAAGTGGACGGGCCCTACTATTTCACAGTCTTGGCCCTTCACATCCTGCCCCCTGAGCAGT
GGAGAGCCACACGTGTGGAAATCTTGCGGAGGCTGTTGGTGACCTCGCAGGCTCGGGCAGTGGCTCCAGGTGGAGCCACCAGGCTGACAG
ATAAGGCAGTGAAGGACTATTCCGCTTACCGTTCTTCCCTTCTCTTTTGGGCCCTCGTCGATCTCATTTACAACATGTTTAAGAAGGTGC
CTACCAGTAACACAGAGGGAGGCTGGTCCTGCTCTCTCGCTGAGTACATCCGCCACAACGACATGCCCATCTACGAAGCTGCCGACAAAG
CCCTGAAAACCTTCCAGGAGGAGTTCATGCCAGTGGAGACCTTCTCAGAGTTCCTCGATGTGGCCGGTCTTTTATCAGAAATCACCGATC
CAGAGAGCTTCCTGAAGGACCTGTTGAACTCAGTCCCCTGACCACCACACAGCAGCTGCGGCGGCGAAGACGAAGCTGGCTTGCCTTCCA
CCCTCTGTTCTCCCTCCTTGTGCATTAAGTTCCCTCCGCGGGATGCTGCATTGTTACCCCGCCCTCCCCTCTCTCATTTTTCTTGGTGTG
GCTTGGGGTTTTTAGGCTTCCTGTTTTATCTCGTGTGTGTGGTGCACCAGCTATGAGGTTGTCTGTAACCCAAGCCATCAAAGGGCCTGT
ACATACCTAGGAGCCATGAGTTGTCCCGGCCAGCTTCATACTTGAGTGTGCACATCTTGAGAAATAAACAAGTGACTTAACACACATTGA

>13016_13016_6_CAPZB-UBR4_CAPZB_chr1_19811930_ENST00000375142_UBR4_chr1_19415471_ENST00000375226_length(amino acids)=447AA_BP=1
MVLIGTDSIPNLHKLEQVSSDEGIGTLAENLLEALREHPDVNKKIDAARRETRAEKKRMAMAMRQKALGTLGMTTNEKGQVVTKTALLKQ
MEELIEEPGLTCCICREGYKFQPTKVLGIYTFTKRVALEEMENKPRKQQGYSTVSHFNIVHYDCHLAAVRLARGREEWESAALQNANTKC
NGLLPVWGPHVPESAFATCLARHNTYLQECTGQREPTYQLNIHDIKLLFLRFAMEQSFSADTGGGGRESNIHLIPYIIHTVLYVLNTTRA
TSREEKNLQGFLEQPKEKWVESAFEVDGPYYFTVLALHILPPEQWRATRVEILRRLLVTSQARAVAPGGATRLTDKAVKDYSAYRSSLLF

--------------------------------------------------------------
>13016_13016_7_CAPZB-UBR4_CAPZB_chr1_19811930_ENST00000375142_UBR4_chr1_19415471_ENST00000375254_length(transcript)=1717nt_BP=50nt
GGAGAGCCACTGACGCCGGGACCGGGACCGCCGCCGCCGCCGCCACCATGGTTCTGATTGGAACTGATTCCATCCCGAACCTGCATAAGC
TGGAGCAGGTGTCCAGTGATGAGGGCATTGGGACCTTGGCAGAGAACCTGCTGGAAGCCCTGCGGGAACACCCTGACGTAAACAAGAAGA
TTGACGCAGCCCGCAGGGAGACCCGGGCAGAGAAGAAGCGCATGGCCATGGCAATGAGGCAGAAGGCCCTGGGCACCCTGGGCATGACGA
CAAATGAAAAGGGCCAGGTCGTGACCAAGACAGCACTCCTGAAGCAGATGGAAGAGCTGATCGAGGAGCCTGGCCTCACGTGCTGCATCT
GCAGGGAGGGATACAAGTTCCAGCCCACAAAGGTCCTGGGCATTTATACCTTCACGAAGCGGGTAGCCTTGGAGGAGATGGAGAATAAGC
CCCGGAAACAGCAGGGCTACAGCACCGTGTCCCACTTCAACATTGTGCACTACGACTGCCATCTGGCTGCCGTCAGGTTGGCTCGAGGCC
GGGAAGAGTGGGAGAGTGCCGCCCTGCAGAATGCCAACACCAAGTGCAACGGGCTCCTTCCGGTCTGGGGACCTCATGTCCCTGAATCAG
CTTTTGCCACTTGCTTGGCAAGACACAACACTTACCTCCAGGAATGTACAGGCCAGCGGGAGCCCACGTATCAGCTCAACATCCATGACA
TCAAACTGCTCTTCCTGCGCTTCGCCATGGAGCAGTCGTTCAGCGCAGACACTGGCGGGGGCGGCCGGGAGAGCAACATCCACCTGATCC
CGTACATCATTCACACTGTGCTTTACGTCCTGAACACAACCCGAGCAACTTCCCGAGAAGAGAAGAACCTCCAAGGCTTTCTGGAACAGC
CCAAGGAGAAGTGGGTGGAGAGTGCCTTTGAAGTGGACGGGCCCTACTATTTCACAGTCTTGGCCCTTCACATCCTGCCCCCTGAGCAGT
GGAGAGCCACACGTGTGGAAATCTTGCGGAGGCTGTTGGTGACCTCGCAGGCTCGGGCAGTGGCTCCAGGTGGAGCCACCAGGCTGACAG
ATAAGGCAGTGAAGGACTATTCCGCTTACCGTTCTTCCCTTCTCTTTTGGGCCCTCGTCGATCTCATTTACAACATGTTTAAGAAGGTGC
CTACCAGTAACACAGAGGGAGGCTGGTCCTGCTCTCTCGCTGAGTACATCCGCCACAACGACATGCCCATCTACGAAGCTGCCGACAAAG
CCCTGAAAACCTTCCAGGAGGAGTTCATGCCAGTGGAGACCTTCTCAGAGTTCCTCGATGTGGCCGGTCTTTTATCAGAAATCACCGATC
CAGAGAGCTTCCTGAAGGACCTGTTGAACTCAGTCCCCTGACCACCACACAGCAGCTGCGGCGGCGAAGACGAAGCTGGCTTGCCTTCCA
CCCTCTGTTCTCCCTCCTTGTGCATTAAGTTCCCTCCGCGGGATGCTGCATTGTTACCCCGCCCTCCCCTCTCTCATTTTTCTTGGTGTG
GCTTGGGGTTTTTAGGCTTCCTGTTTTATCTCGTGTGTGTGGTGCACCAGCTATGAGGTTGTCTGTAACCCAAGCCATCAAAGGGCCTGT
ACATACCTAGGAGCCATGAGTTGTCCCGGCCAGCTTCATACTTGAGTGTGCACATCTTGAGAAATAAACAAGTGACTTAACACACATTGA

>13016_13016_7_CAPZB-UBR4_CAPZB_chr1_19811930_ENST00000375142_UBR4_chr1_19415471_ENST00000375254_length(amino acids)=447AA_BP=1
MVLIGTDSIPNLHKLEQVSSDEGIGTLAENLLEALREHPDVNKKIDAARRETRAEKKRMAMAMRQKALGTLGMTTNEKGQVVTKTALLKQ
MEELIEEPGLTCCICREGYKFQPTKVLGIYTFTKRVALEEMENKPRKQQGYSTVSHFNIVHYDCHLAAVRLARGREEWESAALQNANTKC
NGLLPVWGPHVPESAFATCLARHNTYLQECTGQREPTYQLNIHDIKLLFLRFAMEQSFSADTGGGGRESNIHLIPYIIHTVLYVLNTTRA
TSREEKNLQGFLEQPKEKWVESAFEVDGPYYFTVLALHILPPEQWRATRVEILRRLLVTSQARAVAPGGATRLTDKAVKDYSAYRSSLLF

--------------------------------------------------------------
>13016_13016_8_CAPZB-UBR4_CAPZB_chr1_19811930_ENST00000375142_UBR4_chr1_19415471_ENST00000375267_length(transcript)=1780nt_BP=50nt
GGAGAGCCACTGACGCCGGGACCGGGACCGCCGCCGCCGCCGCCACCATGGTTCTGATTGGAACTGATTCCATCCCGAACCTGCATAAGC
TGGAGCAGGTGTCCAGTGATGAGGGCATTGGGACCTTGGCAGAGAACCTGCTGGAAGCCCTGCGGGAACACCCTGACGTAAACAAGAAGA
TTGACGCAGCCCGCAGGGAGACCCGGGCAGAGAAGAAGCGCATGGCCATGGCAATGAGGCAGAAGGCCCTGGGCACCCTGGGCATGACGA
CAAATGAAAAGGGCCAGGTCGTGACCAAGACAGCACTCCTGAAGCAGATGGAAGAGCTGATCGAGGAGCCTGGCCTCACGTGCTGCATCT
GCAGGGAGGGATACAAGTTCCAGCCCACAAAGGTCCTGGGCATTTATACCTTCACGAAGCGGGTAGCCTTGGAGGAGATGGAGAATAAGC
CCCGGAAACAGCAGGGCTACAGCACCGTGTCCCACTTCAACATTGTGCACTACGACTGCCATCTGGCTGCCGTCAGGTTGGCTCGAGGCC
GGGAAGAGTGGGAGAGTGCCGCCCTGCAGAATGCCAACACCAAGTGCAACGGGCTCCTTCCGGTCTGGGGACCTCATGTCCCTGAATCAG
CTTTTGCCACTTGCTTGGCAAGACACAACACTTACCTCCAGGAATGTACAGGCCAGCGGGAGCCCACGTATCAGCTCAACATCCATGACA
TCAAACTGCTCTTCCTGCGCTTCGCCATGGAGCAGTCGTTCAGCGCAGACACTGGCGGGGGCGGCCGGGAGAGCAACATCCACCTGATCC
CGTACATCATTCACACTGTGCTTTACGTCCTGAACACAACCCGAGCAACTTCCCGAGAAGAGAAGAACCTCCAAGGCTTTCTGGAACAGC
CCAAGGAGAAGTGGGTGGAGAGTGCCTTTGAAGTGGACGGGCCCTACTATTTCACAGTCTTGGCCCTTCACATCCTGCCCCCTGAGCAGT
GGAGAGCCACACGTGTGGAAATCTTGCGGAGGCTGTTGGTGACCTCGCAGGCTCGGGCAGTGGCTCCAGGTGGAGCCACCAGGCTGACAG
ATAAGGCAGTGAAGGACTATTCCGCTTACCGTTCTTCCCTTCTCTTTTGGGCCCTCGTCGATCTCATTTACAACATGTTTAAGAAACAAA
CAACCCCAACTGTGGGAGGGATTGACACTGGCAGCCTGGAGCCTTGTGTCTGTGAGAAGGTGCCTACCAGTAACACAGAGGGAGGCTGGT
CCTGCTCTCTCGCTGAGTACATCCGCCACAACGACATGCCCATCTACGAAGCTGCCGACAAAGCCCTGAAAACCTTCCAGGAGGAGTTCA
TGCCAGTGGAGACCTTCTCAGAGTTCCTCGATGTGGCCGGTCTTTTATCAGAAATCACCGATCCAGAGAGCTTCCTGAAGGACCTGTTGA
ACTCAGTCCCCTGACCACCACACAGCAGCTGCGGCGGCGAAGACGAAGCTGGCTTGCCTTCCACCCTCTGTTCTCCCTCCTTGTGCATTA
AGTTCCCTCCGCGGGATGCTGCATTGTTACCCCGCCCTCCCCTCTCTCATTTTTCTTGGTGTGGCTTGGGGTTTTTAGGCTTCCTGTTTT
ATCTCGTGTGTGTGGTGCACCAGCTATGAGGTTGTCTGTAACCCAAGCCATCAAAGGGCCTGTACATACCTAGGAGCCATGAGTTGTCCC

>13016_13016_8_CAPZB-UBR4_CAPZB_chr1_19811930_ENST00000375142_UBR4_chr1_19415471_ENST00000375267_length(amino acids)=468AA_BP=1
MVLIGTDSIPNLHKLEQVSSDEGIGTLAENLLEALREHPDVNKKIDAARRETRAEKKRMAMAMRQKALGTLGMTTNEKGQVVTKTALLKQ
MEELIEEPGLTCCICREGYKFQPTKVLGIYTFTKRVALEEMENKPRKQQGYSTVSHFNIVHYDCHLAAVRLARGREEWESAALQNANTKC
NGLLPVWGPHVPESAFATCLARHNTYLQECTGQREPTYQLNIHDIKLLFLRFAMEQSFSADTGGGGRESNIHLIPYIIHTVLYVLNTTRA
TSREEKNLQGFLEQPKEKWVESAFEVDGPYYFTVLALHILPPEQWRATRVEILRRLLVTSQARAVAPGGATRLTDKAVKDYSAYRSSLLF
WALVDLIYNMFKKQTTPTVGGIDTGSLEPCVCEKVPTSNTEGGWSCSLAEYIRHNDMPIYEAADKALKTFQEEFMPVETFSEFLDVAGLL

--------------------------------------------------------------
>13016_13016_9_CAPZB-UBR4_CAPZB_chr1_19811930_ENST00000401084_UBR4_chr1_19415471_ENST00000375217_length(transcript)=1804nt_BP=137nt
GCCCGGCGCGGGGGGAGGGGGGTGCTGACCCGGATGTTCACTCCTGGGCACCCGGGGAAGTGGAAGCGCCGGGCCCTGCTGCGGGGGGGA
GAGCCACTGACGCCGGGACCGGGACCGCCGCCGCCGCCGCCACCATGGTTCTGATTGGAACTGATTCCATCCCGAACCTGCATAAGCTGG
AGCAGGTGTCCAGTGATGAGGGCATTGGGACCTTGGCAGAGAACCTGCTGGAAGCCCTGCGGGAACACCCTGACGTAAACAAGAAGATTG
ACGCAGCCCGCAGGGAGACCCGGGCAGAGAAGAAGCGCATGGCCATGGCAATGAGGCAGAAGGCCCTGGGCACCCTGGGCATGACGACAA
ATGAAAAGGGCCAGGTCGTGACCAAGACAGCACTCCTGAAGCAGATGGAAGAGCTGATCGAGGAGCCTGGCCTCACGTGCTGCATCTGCA
GGGAGGGATACAAGTTCCAGCCCACAAAGGTCCTGGGCATTTATACCTTCACGAAGCGGGTAGCCTTGGAGGAGATGGAGAATAAGCCCC
GGAAACAGCAGGGCTACAGCACCGTGTCCCACTTCAACATTGTGCACTACGACTGCCATCTGGCTGCCGTCAGGTTGGCTCGAGGCCGGG
AAGAGTGGGAGAGTGCCGCCCTGCAGAATGCCAACACCAAGTGCAACGGGCTCCTTCCGGTCTGGGGACCTCATGTCCCTGAATCAGCTT
TTGCCACTTGCTTGGCAAGACACAACACTTACCTCCAGGAATGTACAGGCCAGCGGGAGCCCACGTATCAGCTCAACATCCATGACATCA
AACTGCTCTTCCTGCGCTTCGCCATGGAGCAGTCGTTCAGCGCAGACACTGGCGGGGGCGGCCGGGAGAGCAACATCCACCTGATCCCGT
ACATCATTCACACTGTGCTTTACGTCCTGAACACAACCCGAGCAACTTCCCGAGAAGAGAAGAACCTCCAAGGCTTTCTGGAACAGCCCA
AGGAGAAGTGGGTGGAGAGTGCCTTTGAAGTGGACGGGCCCTACTATTTCACAGTCTTGGCCCTTCACATCCTGCCCCCTGAGCAGTGGA
GAGCCACACGTGTGGAAATCTTGCGGAGGCTGTTGGTGACCTCGCAGGCTCGGGCAGTGGCTCCAGGTGGAGCCACCAGGCTGACAGATA
AGGCAGTGAAGGACTATTCCGCTTACCGTTCTTCCCTTCTCTTTTGGGCCCTCGTCGATCTCATTTACAACATGTTTAAGAAGGTGCCTA
CCAGTAACACAGAGGGAGGCTGGTCCTGCTCTCTCGCTGAGTACATCCGCCACAACGACATGCCCATCTACGAAGCTGCCGACAAAGCCC
TGAAAACCTTCCAGGAGGAGTTCATGCCAGTGGAGACCTTCTCAGAGTTCCTCGATGTGGCCGGTCTTTTATCAGAAATCACCGATCCAG
AGAGCTTCCTGAAGGACCTGTTGAACTCAGTCCCCTGACCACCACACAGCAGCTGCGGCGGCGAAGACGAAGCTGGCTTGCCTTCCACCC
TCTGTTCTCCCTCCTTGTGCATTAAGTTCCCTCCGCGGGATGCTGCATTGTTACCCCGCCCTCCCCTCTCTCATTTTTCTTGGTGTGGCT
TGGGGTTTTTAGGCTTCCTGTTTTATCTCGTGTGTGTGGTGCACCAGCTATGAGGTTGTCTGTAACCCAAGCCATCAAAGGGCCTGTACA
TACCTAGGAGCCATGAGTTGTCCCGGCCAGCTTCATACTTGAGTGTGCACATCTTGAGAAATAAACAAGTGACTTAACACACATTGAAAA

>13016_13016_9_CAPZB-UBR4_CAPZB_chr1_19811930_ENST00000401084_UBR4_chr1_19415471_ENST00000375217_length(amino acids)=447AA_BP=1
MVLIGTDSIPNLHKLEQVSSDEGIGTLAENLLEALREHPDVNKKIDAARRETRAEKKRMAMAMRQKALGTLGMTTNEKGQVVTKTALLKQ
MEELIEEPGLTCCICREGYKFQPTKVLGIYTFTKRVALEEMENKPRKQQGYSTVSHFNIVHYDCHLAAVRLARGREEWESAALQNANTKC
NGLLPVWGPHVPESAFATCLARHNTYLQECTGQREPTYQLNIHDIKLLFLRFAMEQSFSADTGGGGRESNIHLIPYIIHTVLYVLNTTRA
TSREEKNLQGFLEQPKEKWVESAFEVDGPYYFTVLALHILPPEQWRATRVEILRRLLVTSQARAVAPGGATRLTDKAVKDYSAYRSSLLF

--------------------------------------------------------------
>13016_13016_10_CAPZB-UBR4_CAPZB_chr1_19811930_ENST00000401084_UBR4_chr1_19415471_ENST00000375226_length(transcript)=1804nt_BP=137nt
GCCCGGCGCGGGGGGAGGGGGGTGCTGACCCGGATGTTCACTCCTGGGCACCCGGGGAAGTGGAAGCGCCGGGCCCTGCTGCGGGGGGGA
GAGCCACTGACGCCGGGACCGGGACCGCCGCCGCCGCCGCCACCATGGTTCTGATTGGAACTGATTCCATCCCGAACCTGCATAAGCTGG
AGCAGGTGTCCAGTGATGAGGGCATTGGGACCTTGGCAGAGAACCTGCTGGAAGCCCTGCGGGAACACCCTGACGTAAACAAGAAGATTG
ACGCAGCCCGCAGGGAGACCCGGGCAGAGAAGAAGCGCATGGCCATGGCAATGAGGCAGAAGGCCCTGGGCACCCTGGGCATGACGACAA
ATGAAAAGGGCCAGGTCGTGACCAAGACAGCACTCCTGAAGCAGATGGAAGAGCTGATCGAGGAGCCTGGCCTCACGTGCTGCATCTGCA
GGGAGGGATACAAGTTCCAGCCCACAAAGGTCCTGGGCATTTATACCTTCACGAAGCGGGTAGCCTTGGAGGAGATGGAGAATAAGCCCC
GGAAACAGCAGGGCTACAGCACCGTGTCCCACTTCAACATTGTGCACTACGACTGCCATCTGGCTGCCGTCAGGTTGGCTCGAGGCCGGG
AAGAGTGGGAGAGTGCCGCCCTGCAGAATGCCAACACCAAGTGCAACGGGCTCCTTCCGGTCTGGGGACCTCATGTCCCTGAATCAGCTT
TTGCCACTTGCTTGGCAAGACACAACACTTACCTCCAGGAATGTACAGGCCAGCGGGAGCCCACGTATCAGCTCAACATCCATGACATCA
AACTGCTCTTCCTGCGCTTCGCCATGGAGCAGTCGTTCAGCGCAGACACTGGCGGGGGCGGCCGGGAGAGCAACATCCACCTGATCCCGT
ACATCATTCACACTGTGCTTTACGTCCTGAACACAACCCGAGCAACTTCCCGAGAAGAGAAGAACCTCCAAGGCTTTCTGGAACAGCCCA
AGGAGAAGTGGGTGGAGAGTGCCTTTGAAGTGGACGGGCCCTACTATTTCACAGTCTTGGCCCTTCACATCCTGCCCCCTGAGCAGTGGA
GAGCCACACGTGTGGAAATCTTGCGGAGGCTGTTGGTGACCTCGCAGGCTCGGGCAGTGGCTCCAGGTGGAGCCACCAGGCTGACAGATA
AGGCAGTGAAGGACTATTCCGCTTACCGTTCTTCCCTTCTCTTTTGGGCCCTCGTCGATCTCATTTACAACATGTTTAAGAAGGTGCCTA
CCAGTAACACAGAGGGAGGCTGGTCCTGCTCTCTCGCTGAGTACATCCGCCACAACGACATGCCCATCTACGAAGCTGCCGACAAAGCCC
TGAAAACCTTCCAGGAGGAGTTCATGCCAGTGGAGACCTTCTCAGAGTTCCTCGATGTGGCCGGTCTTTTATCAGAAATCACCGATCCAG
AGAGCTTCCTGAAGGACCTGTTGAACTCAGTCCCCTGACCACCACACAGCAGCTGCGGCGGCGAAGACGAAGCTGGCTTGCCTTCCACCC
TCTGTTCTCCCTCCTTGTGCATTAAGTTCCCTCCGCGGGATGCTGCATTGTTACCCCGCCCTCCCCTCTCTCATTTTTCTTGGTGTGGCT
TGGGGTTTTTAGGCTTCCTGTTTTATCTCGTGTGTGTGGTGCACCAGCTATGAGGTTGTCTGTAACCCAAGCCATCAAAGGGCCTGTACA
TACCTAGGAGCCATGAGTTGTCCCGGCCAGCTTCATACTTGAGTGTGCACATCTTGAGAAATAAACAAGTGACTTAACACACATTGAAAA

>13016_13016_10_CAPZB-UBR4_CAPZB_chr1_19811930_ENST00000401084_UBR4_chr1_19415471_ENST00000375226_length(amino acids)=447AA_BP=1
MVLIGTDSIPNLHKLEQVSSDEGIGTLAENLLEALREHPDVNKKIDAARRETRAEKKRMAMAMRQKALGTLGMTTNEKGQVVTKTALLKQ
MEELIEEPGLTCCICREGYKFQPTKVLGIYTFTKRVALEEMENKPRKQQGYSTVSHFNIVHYDCHLAAVRLARGREEWESAALQNANTKC
NGLLPVWGPHVPESAFATCLARHNTYLQECTGQREPTYQLNIHDIKLLFLRFAMEQSFSADTGGGGRESNIHLIPYIIHTVLYVLNTTRA
TSREEKNLQGFLEQPKEKWVESAFEVDGPYYFTVLALHILPPEQWRATRVEILRRLLVTSQARAVAPGGATRLTDKAVKDYSAYRSSLLF

--------------------------------------------------------------
>13016_13016_11_CAPZB-UBR4_CAPZB_chr1_19811930_ENST00000401084_UBR4_chr1_19415471_ENST00000375254_length(transcript)=1804nt_BP=137nt
GCCCGGCGCGGGGGGAGGGGGGTGCTGACCCGGATGTTCACTCCTGGGCACCCGGGGAAGTGGAAGCGCCGGGCCCTGCTGCGGGGGGGA
GAGCCACTGACGCCGGGACCGGGACCGCCGCCGCCGCCGCCACCATGGTTCTGATTGGAACTGATTCCATCCCGAACCTGCATAAGCTGG
AGCAGGTGTCCAGTGATGAGGGCATTGGGACCTTGGCAGAGAACCTGCTGGAAGCCCTGCGGGAACACCCTGACGTAAACAAGAAGATTG
ACGCAGCCCGCAGGGAGACCCGGGCAGAGAAGAAGCGCATGGCCATGGCAATGAGGCAGAAGGCCCTGGGCACCCTGGGCATGACGACAA
ATGAAAAGGGCCAGGTCGTGACCAAGACAGCACTCCTGAAGCAGATGGAAGAGCTGATCGAGGAGCCTGGCCTCACGTGCTGCATCTGCA
GGGAGGGATACAAGTTCCAGCCCACAAAGGTCCTGGGCATTTATACCTTCACGAAGCGGGTAGCCTTGGAGGAGATGGAGAATAAGCCCC
GGAAACAGCAGGGCTACAGCACCGTGTCCCACTTCAACATTGTGCACTACGACTGCCATCTGGCTGCCGTCAGGTTGGCTCGAGGCCGGG
AAGAGTGGGAGAGTGCCGCCCTGCAGAATGCCAACACCAAGTGCAACGGGCTCCTTCCGGTCTGGGGACCTCATGTCCCTGAATCAGCTT
TTGCCACTTGCTTGGCAAGACACAACACTTACCTCCAGGAATGTACAGGCCAGCGGGAGCCCACGTATCAGCTCAACATCCATGACATCA
AACTGCTCTTCCTGCGCTTCGCCATGGAGCAGTCGTTCAGCGCAGACACTGGCGGGGGCGGCCGGGAGAGCAACATCCACCTGATCCCGT
ACATCATTCACACTGTGCTTTACGTCCTGAACACAACCCGAGCAACTTCCCGAGAAGAGAAGAACCTCCAAGGCTTTCTGGAACAGCCCA
AGGAGAAGTGGGTGGAGAGTGCCTTTGAAGTGGACGGGCCCTACTATTTCACAGTCTTGGCCCTTCACATCCTGCCCCCTGAGCAGTGGA
GAGCCACACGTGTGGAAATCTTGCGGAGGCTGTTGGTGACCTCGCAGGCTCGGGCAGTGGCTCCAGGTGGAGCCACCAGGCTGACAGATA
AGGCAGTGAAGGACTATTCCGCTTACCGTTCTTCCCTTCTCTTTTGGGCCCTCGTCGATCTCATTTACAACATGTTTAAGAAGGTGCCTA
CCAGTAACACAGAGGGAGGCTGGTCCTGCTCTCTCGCTGAGTACATCCGCCACAACGACATGCCCATCTACGAAGCTGCCGACAAAGCCC
TGAAAACCTTCCAGGAGGAGTTCATGCCAGTGGAGACCTTCTCAGAGTTCCTCGATGTGGCCGGTCTTTTATCAGAAATCACCGATCCAG
AGAGCTTCCTGAAGGACCTGTTGAACTCAGTCCCCTGACCACCACACAGCAGCTGCGGCGGCGAAGACGAAGCTGGCTTGCCTTCCACCC
TCTGTTCTCCCTCCTTGTGCATTAAGTTCCCTCCGCGGGATGCTGCATTGTTACCCCGCCCTCCCCTCTCTCATTTTTCTTGGTGTGGCT
TGGGGTTTTTAGGCTTCCTGTTTTATCTCGTGTGTGTGGTGCACCAGCTATGAGGTTGTCTGTAACCCAAGCCATCAAAGGGCCTGTACA
TACCTAGGAGCCATGAGTTGTCCCGGCCAGCTTCATACTTGAGTGTGCACATCTTGAGAAATAAACAAGTGACTTAACACACATTGAAAA

>13016_13016_11_CAPZB-UBR4_CAPZB_chr1_19811930_ENST00000401084_UBR4_chr1_19415471_ENST00000375254_length(amino acids)=447AA_BP=1
MVLIGTDSIPNLHKLEQVSSDEGIGTLAENLLEALREHPDVNKKIDAARRETRAEKKRMAMAMRQKALGTLGMTTNEKGQVVTKTALLKQ
MEELIEEPGLTCCICREGYKFQPTKVLGIYTFTKRVALEEMENKPRKQQGYSTVSHFNIVHYDCHLAAVRLARGREEWESAALQNANTKC
NGLLPVWGPHVPESAFATCLARHNTYLQECTGQREPTYQLNIHDIKLLFLRFAMEQSFSADTGGGGRESNIHLIPYIIHTVLYVLNTTRA
TSREEKNLQGFLEQPKEKWVESAFEVDGPYYFTVLALHILPPEQWRATRVEILRRLLVTSQARAVAPGGATRLTDKAVKDYSAYRSSLLF

--------------------------------------------------------------
>13016_13016_12_CAPZB-UBR4_CAPZB_chr1_19811930_ENST00000401084_UBR4_chr1_19415471_ENST00000375267_length(transcript)=1867nt_BP=137nt
GCCCGGCGCGGGGGGAGGGGGGTGCTGACCCGGATGTTCACTCCTGGGCACCCGGGGAAGTGGAAGCGCCGGGCCCTGCTGCGGGGGGGA
GAGCCACTGACGCCGGGACCGGGACCGCCGCCGCCGCCGCCACCATGGTTCTGATTGGAACTGATTCCATCCCGAACCTGCATAAGCTGG
AGCAGGTGTCCAGTGATGAGGGCATTGGGACCTTGGCAGAGAACCTGCTGGAAGCCCTGCGGGAACACCCTGACGTAAACAAGAAGATTG
ACGCAGCCCGCAGGGAGACCCGGGCAGAGAAGAAGCGCATGGCCATGGCAATGAGGCAGAAGGCCCTGGGCACCCTGGGCATGACGACAA
ATGAAAAGGGCCAGGTCGTGACCAAGACAGCACTCCTGAAGCAGATGGAAGAGCTGATCGAGGAGCCTGGCCTCACGTGCTGCATCTGCA
GGGAGGGATACAAGTTCCAGCCCACAAAGGTCCTGGGCATTTATACCTTCACGAAGCGGGTAGCCTTGGAGGAGATGGAGAATAAGCCCC
GGAAACAGCAGGGCTACAGCACCGTGTCCCACTTCAACATTGTGCACTACGACTGCCATCTGGCTGCCGTCAGGTTGGCTCGAGGCCGGG
AAGAGTGGGAGAGTGCCGCCCTGCAGAATGCCAACACCAAGTGCAACGGGCTCCTTCCGGTCTGGGGACCTCATGTCCCTGAATCAGCTT
TTGCCACTTGCTTGGCAAGACACAACACTTACCTCCAGGAATGTACAGGCCAGCGGGAGCCCACGTATCAGCTCAACATCCATGACATCA
AACTGCTCTTCCTGCGCTTCGCCATGGAGCAGTCGTTCAGCGCAGACACTGGCGGGGGCGGCCGGGAGAGCAACATCCACCTGATCCCGT
ACATCATTCACACTGTGCTTTACGTCCTGAACACAACCCGAGCAACTTCCCGAGAAGAGAAGAACCTCCAAGGCTTTCTGGAACAGCCCA
AGGAGAAGTGGGTGGAGAGTGCCTTTGAAGTGGACGGGCCCTACTATTTCACAGTCTTGGCCCTTCACATCCTGCCCCCTGAGCAGTGGA
GAGCCACACGTGTGGAAATCTTGCGGAGGCTGTTGGTGACCTCGCAGGCTCGGGCAGTGGCTCCAGGTGGAGCCACCAGGCTGACAGATA
AGGCAGTGAAGGACTATTCCGCTTACCGTTCTTCCCTTCTCTTTTGGGCCCTCGTCGATCTCATTTACAACATGTTTAAGAAACAAACAA
CCCCAACTGTGGGAGGGATTGACACTGGCAGCCTGGAGCCTTGTGTCTGTGAGAAGGTGCCTACCAGTAACACAGAGGGAGGCTGGTCCT
GCTCTCTCGCTGAGTACATCCGCCACAACGACATGCCCATCTACGAAGCTGCCGACAAAGCCCTGAAAACCTTCCAGGAGGAGTTCATGC
CAGTGGAGACCTTCTCAGAGTTCCTCGATGTGGCCGGTCTTTTATCAGAAATCACCGATCCAGAGAGCTTCCTGAAGGACCTGTTGAACT
CAGTCCCCTGACCACCACACAGCAGCTGCGGCGGCGAAGACGAAGCTGGCTTGCCTTCCACCCTCTGTTCTCCCTCCTTGTGCATTAAGT
TCCCTCCGCGGGATGCTGCATTGTTACCCCGCCCTCCCCTCTCTCATTTTTCTTGGTGTGGCTTGGGGTTTTTAGGCTTCCTGTTTTATC
TCGTGTGTGTGGTGCACCAGCTATGAGGTTGTCTGTAACCCAAGCCATCAAAGGGCCTGTACATACCTAGGAGCCATGAGTTGTCCCGGC

>13016_13016_12_CAPZB-UBR4_CAPZB_chr1_19811930_ENST00000401084_UBR4_chr1_19415471_ENST00000375267_length(amino acids)=468AA_BP=1
MVLIGTDSIPNLHKLEQVSSDEGIGTLAENLLEALREHPDVNKKIDAARRETRAEKKRMAMAMRQKALGTLGMTTNEKGQVVTKTALLKQ
MEELIEEPGLTCCICREGYKFQPTKVLGIYTFTKRVALEEMENKPRKQQGYSTVSHFNIVHYDCHLAAVRLARGREEWESAALQNANTKC
NGLLPVWGPHVPESAFATCLARHNTYLQECTGQREPTYQLNIHDIKLLFLRFAMEQSFSADTGGGGRESNIHLIPYIIHTVLYVLNTTRA
TSREEKNLQGFLEQPKEKWVESAFEVDGPYYFTVLALHILPPEQWRATRVEILRRLLVTSQARAVAPGGATRLTDKAVKDYSAYRSSLLF
WALVDLIYNMFKKQTTPTVGGIDTGSLEPCVCEKVPTSNTEGGWSCSLAEYIRHNDMPIYEAADKALKTFQEEFMPVETFSEFLDVAGLL

--------------------------------------------------------------

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Fusion Gene PPI Analysis for CAPZB-UBR4


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CAPZB-UBR4


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CAPZB-UBR4


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneCAPZBC0007097Carcinoma1CTD_human
HgeneCAPZBC0024667Animal Mammary Neoplasms1CTD_human
HgeneCAPZBC0024668Mammary Neoplasms, Experimental1CTD_human
HgeneCAPZBC0205696Anaplastic carcinoma1CTD_human
HgeneCAPZBC0205697Carcinoma, Spindle-Cell1CTD_human
HgeneCAPZBC0205698Undifferentiated carcinoma1CTD_human
HgeneCAPZBC0205699Carcinomatosis1CTD_human
HgeneCAPZBC0948089Acute Coronary Syndrome1CTD_human
HgeneCAPZBC1257925Mammary Carcinoma, Animal1CTD_human
TgeneC1720189Episodic Ataxia1GENOMICS_ENGLAND
TgeneC4015108Episodic ataxia with slurred speech1GENOMICS_ENGLAND