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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Fusion gene:BRMS1L-ZNF839 (FusionGDB2 ID:HG84312TG55778)

Fusion Gene Summary for BRMS1L-ZNF839

check button Fusion gene summary
Fusion gene informationFusion gene name: BRMS1L-ZNF839
Fusion gene ID: hg84312tg55778
HgeneTgene
Gene symbol

BRMS1L

ZNF839

Gene ID

84312

55778

Gene nameBRMS1 like transcriptional repressorzinc finger protein 839
SynonymsBRMS1C14orf131
Cytomap('BRMS1L')('ZNF839')

14q13.2

14q32.31

Type of geneprotein-codingprotein-coding
Descriptionbreast cancer metastasis-suppressor 1-like proteinBRMS1-homolog protein p40BRMS1-like protein p40breast cancer metastasis-suppressor 1breast cancer metastasis-suppressor 1 likezinc finger protein 839renal carcinoma antigen NY-REN-50
Modification date2020031320200313
UniProtAcc

Q5PSV4

.
Ensembl transtripts involved in fusion geneENST00000216807, ENST00000543183, 
Fusion gene scores* DoF score5 X 4 X 4=802 X 2 X 2=8
# samples 52
** MAII scorelog2(5/80*10)=-0.678071905112638
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(2/8*10)=1.32192809488736
Context

PubMed: BRMS1L [Title/Abstract] AND ZNF839 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointBRMS1L(36304129)-ZNF839(102805153), # samples:3
Anticipated loss of major functional domain due to fusion event.BRMS1L-ZNF839 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
BRMS1L-ZNF839 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across BRMS1L (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across ZNF839 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4ACCTCGA-OR-A5KW-01ABRMS1Lchr14

36304129

-ZNF839chr14

102805153

+
ChimerDB4ACCTCGA-OR-A5KW-01ABRMS1Lchr14

36304129

+ZNF839chr14

102805153

+


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Fusion Gene ORF analysis for BRMS1L-ZNF839

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000216807ENST00000420933BRMS1Lchr14

36304129

+ZNF839chr14

102805153

+
5CDS-3UTRENST00000543183ENST00000420933BRMS1Lchr14

36304129

+ZNF839chr14

102805153

+
In-frameENST00000216807ENST00000262236BRMS1Lchr14

36304129

+ZNF839chr14

102805153

+
In-frameENST00000216807ENST00000442396BRMS1Lchr14

36304129

+ZNF839chr14

102805153

+
In-frameENST00000216807ENST00000558850BRMS1Lchr14

36304129

+ZNF839chr14

102805153

+
In-frameENST00000216807ENST00000559185BRMS1Lchr14

36304129

+ZNF839chr14

102805153

+
In-frameENST00000543183ENST00000262236BRMS1Lchr14

36304129

+ZNF839chr14

102805153

+
In-frameENST00000543183ENST00000442396BRMS1Lchr14

36304129

+ZNF839chr14

102805153

+
In-frameENST00000543183ENST00000558850BRMS1Lchr14

36304129

+ZNF839chr14

102805153

+
In-frameENST00000543183ENST00000559185BRMS1Lchr14

36304129

+ZNF839chr14

102805153

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000216807BRMS1Lchr1436304129+ENST00000558850ZNF839chr14102805153+19506401601764534
ENST00000216807BRMS1Lchr1436304129+ENST00000559185ZNF839chr14102805153+19536401601764534
ENST00000216807BRMS1Lchr1436304129+ENST00000442396ZNF839chr14102805153+19536401601764534
ENST00000216807BRMS1Lchr1436304129+ENST00000262236ZNF839chr14102805153+22996401601770536
ENST00000543183BRMS1Lchr1436304129+ENST00000558850ZNF839chr14102805153+19406303331754473
ENST00000543183BRMS1Lchr1436304129+ENST00000559185ZNF839chr14102805153+19436303331754473
ENST00000543183BRMS1Lchr1436304129+ENST00000442396ZNF839chr14102805153+19436303331754473
ENST00000543183BRMS1Lchr1436304129+ENST00000262236ZNF839chr14102805153+22896303331760475

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000216807ENST00000558850BRMS1Lchr1436304129+ZNF839chr14102805153+0.0057733150.9942267
ENST00000216807ENST00000559185BRMS1Lchr1436304129+ZNF839chr14102805153+0.0058895580.9941104
ENST00000216807ENST00000442396BRMS1Lchr1436304129+ZNF839chr14102805153+0.0058895580.9941104
ENST00000216807ENST00000262236BRMS1Lchr1436304129+ZNF839chr14102805153+0.0044533110.9955467
ENST00000543183ENST00000558850BRMS1Lchr1436304129+ZNF839chr14102805153+0.0079716510.9920284
ENST00000543183ENST00000559185BRMS1Lchr1436304129+ZNF839chr14102805153+0.0082405640.9917595
ENST00000543183ENST00000442396BRMS1Lchr1436304129+ZNF839chr14102805153+0.0082405640.9917595
ENST00000543183ENST00000262236BRMS1Lchr1436304129+ZNF839chr14102805153+0.0062365880.9937634

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Fusion Genomic Features for BRMS1L-ZNF839


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
BRMS1Lchr1436304129+ZNF839chr14102805152+8.10E-080.9999999
BRMS1Lchr1436304129+ZNF839chr14102805152+8.10E-080.9999999

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for BRMS1L-ZNF839


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr14:36304129/chr14:102805153)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
BRMS1L

Q5PSV4

.
FUNCTION: Involved in the histone deacetylase (HDAC1)-dependent transcriptional repression activity. When overexpressed in lung cancer cell line that lacks p53/TP53 expression, inhibits cell growth. {ECO:0000269|PubMed:15451426}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneBRMS1Lchr14:36304129chr14:102805153ENST00000216807+41052_84147324.0Coiled coilOntology_term=ECO:0000255

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneBRMS1Lchr14:36304129chr14:102805153ENST00000216807+410149_180147324.0Coiled coilOntology_term=ECO:0000255
TgeneZNF839chr14:36304129chr14:102805153ENST0000026223648103_108437814.0Compositional biasNote=Poly-Ser
TgeneZNF839chr14:36304129chr14:102805153ENST0000044239648103_108553928.0Compositional biasNote=Poly-Ser
TgeneZNF839chr14:36304129chr14:102805153ENST0000055885048103_108437812.0Compositional biasNote=Poly-Ser
TgeneZNF839chr14:36304129chr14:102805153ENST0000055918548103_108437812.0Compositional biasNote=Poly-Ser
TgeneZNF839chr14:36304129chr14:102805153ENST0000026223648197_222437814.0Zinc fingerC2H2-type
TgeneZNF839chr14:36304129chr14:102805153ENST0000044239648197_222553928.0Zinc fingerC2H2-type
TgeneZNF839chr14:36304129chr14:102805153ENST0000055885048197_222437812.0Zinc fingerC2H2-type
TgeneZNF839chr14:36304129chr14:102805153ENST0000055918548197_222437812.0Zinc fingerC2H2-type


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Fusion Gene Sequence for BRMS1L-ZNF839


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>10318_10318_1_BRMS1L-ZNF839_BRMS1L_chr14_36304129_ENST00000216807_ZNF839_chr14_102805153_ENST00000262236_length(transcript)=2299nt_BP=640nt
GGAAGGCCTCCGCCAATGGCAGAGCTCCCATCGCAGAGCCTGCGGGTTAGGTTGTGAGGCCCGGGCCGGGGGCGGGGAGGAGCCAAGGGG
GCGAGCAAGCTCGGTGGCTGGGTGGGTTGGGGCGTTCCGCGCGCCCTTCATTGAAGCGGCGGTGGCCGGGCTGGGCGCCGGTAGTGGAAA
GCGACGGCGCGGCTGGAAAATGCCAGTCCATTCCCGAGGGGATAAGAAGGAGACCAACCATCACGATGAGATGGAGGTGGACTACGCCGA
AAATGAGGGGAGCAGCTCCGAGGACGAGGACACTGAGAGCTCGTCGGTCTCCGAGGATGGAGATAGCTCAGAAATGGATGATGAAGACTG
TGAAAGAAGAAGAATGGAATGTTTGGATGAAATGTCCAATCTTGAAAAACAGTTTACCGATCTCAAAGATCAACTTTATAAAGAACGATT
AAGTCAGGTGGATGCAAAACTACAAGAAGTCATAGCTGGAAAAGCACCAGAATACTTGGAACCGCTGGCAACTTTACAGGAAAATATGCA
AATTCGTACAAAGGTAGCAGGAATCTATAGAGAGCTCTGCTTAGAATCTGTAAAGAACAAATATGAATGTGAAATTCAAGCTTCTCGCCA
GCATTGTGAGGTTGCTGAGTCATTAGGAATCACAGAATTCCTACGGAAGAAAGAAATACACCCAGACAACCTTGGACCCAAGCACCTCAG
CCGAGACATGGATGGGGAGCAGCTAGAGGGAGCTAGCAGCGAGAAGAGGGAACGTGAGGCTGCGGAGGAGGGACTGGCCTCAGTGAAAAG
GCCCAGAAGAGAAGCCCTGTCCAACGATACCACTGAATCTCTTGCTGCCAACAGCAGAGGCCGGGAGAAGCCCAGGCCCTTGCATGCTTT
GGCCGCTGGTGAGGGTTTTTCCCCTCCAGTAAATGTGACTGTCTCTCCCCGTTCTGAAGAAAGCCATACAACGACGGTTTCTGGTGGCAA
TGGGAGCGTGTTCCAGGCGGGCCCGCAGCTTCAGGCACTGGCTAACTTAGAAGCCAGGAGGGGGTCTATAGGTGCTGCTCTCTCATCCCG
GGATGTCAGTGGGCTGCCTGTTTATGCTCAGTCAGGAGAGCCTAGGAGGCTGACCCAGGCACAGGTGGCAGCGTTTCCTGGAGAGAATGC
TTTGGAACACTCTTCAGACCAGGACACCTGGGACAGCCTGAGGAGCCCGGGTTTCTGCAGCCCTTTGTCATCTGGTGGTGGAGCAGAGTC
CCTGCCGCCTGGGGGGCCTGGACATGCAGAGGCAGGACACCTCGGCAAGGTTTGTGACTTCCACCTGAACCACCAGCAGCCCAGCCCCAC
CAGCGTCCTGCCTACAGAGGTGGCAGCCCCTCCGCTTGAGAAAATTTTGTCTGTGGATAGCGTGGCAGTGGACTGTGCCTACAGGACTGT
GCCCAAGCCAGGGCCTCAGCCTGGCCCACATGGATCACTATTGACTGAAGGGTGTCTCAGAAGCCTTTCGGGGGACTTGAACCGGTTCCC
CTGTGGGATGGAGGTGCACTCTGGCCAGAGAGAACTGGAGAGCGTGGTTGCTGTCGGCGAAGCCATGGCTTTTGAAATTTCCAATGGGAG
CCATGAGTTACTGTCTCAGGGACAGAAGCAGATTTTTATTCAGACTTCCGATGGGCTTATCTTGTCCCCTCCAGGTACAATAGTGTCTCA
GGAGGAGGACATTGTCACAGTGACTGATGCAGAGGGGCGTGCCTGCGGATGGGCCCGCTAGAAGGAGTTCCTCTAGAAGCTGTGGAGTCG
GTCGTCACCGTGGAGCCAGAGCCCTCACAGTGAAGTGGAGTCAGATCCTAGATTCGTCTGATTTTATCCAGAGAAGGTCTATGGCAAGCA
ATGTATATTTTTCTAATGTGAATATTGCACAGATGAACCTTTTATTTATAAAGAATAATGTCTTTCTGCCCTGCTGTCTACATTTTTCTA
TGGAGCTTGTCATAATAATAGCAGATATTACCTGATCAGGAATCCCTGTGGCGCGTCTGACGCTCATGAGTTTTTCATGATGGTGATGAG
TAGCACTGCACTGTCACCTGATGATTGGCCCTGCTCCGTTTCCCTTCTCTCCTGGGAGATATGCTGCTTTTCCACCAGACTTGCTCCATA
CTAGAAGCTTCTTTTGGGTTCAATTAAAAAGAAAATAAGCTAGTCATTCTGGGCAGCATTTTATTGATAGAAGGGGGAAAAAGTCATTTC
TACTTGCATGATTTTTTAAATTAAATTAAATTAAATTAATTTAATTATT

>10318_10318_1_BRMS1L-ZNF839_BRMS1L_chr14_36304129_ENST00000216807_ZNF839_chr14_102805153_ENST00000262236_length(amino acids)=536AA_BP=160
MGAGSGKRRRGWKMPVHSRGDKKETNHHDEMEVDYAENEGSSSEDEDTESSSVSEDGDSSEMDDEDCERRRMECLDEMSNLEKQFTDLKD
QLYKERLSQVDAKLQEVIAGKAPEYLEPLATLQENMQIRTKVAGIYRELCLESVKNKYECEIQASRQHCEVAESLGITEFLRKKEIHPDN
LGPKHLSRDMDGEQLEGASSEKREREAAEEGLASVKRPRREALSNDTTESLAANSRGREKPRPLHALAAGEGFSPPVNVTVSPRSEESHT
TTVSGGNGSVFQAGPQLQALANLEARRGSIGAALSSRDVSGLPVYAQSGEPRRLTQAQVAAFPGENALEHSSDQDTWDSLRSPGFCSPLS
SGGGAESLPPGGPGHAEAGHLGKVCDFHLNHQQPSPTSVLPTEVAAPPLEKILSVDSVAVDCAYRTVPKPGPQPGPHGSLLTEGCLRSLS
GDLNRFPCGMEVHSGQRELESVVAVGEAMAFEISNGSHELLSQGQKQIFIQTSDGLILSPPGTIVSQEEDIVTVTDAEGRACGWAR

--------------------------------------------------------------
>10318_10318_2_BRMS1L-ZNF839_BRMS1L_chr14_36304129_ENST00000216807_ZNF839_chr14_102805153_ENST00000442396_length(transcript)=1953nt_BP=640nt
GGAAGGCCTCCGCCAATGGCAGAGCTCCCATCGCAGAGCCTGCGGGTTAGGTTGTGAGGCCCGGGCCGGGGGCGGGGAGGAGCCAAGGGG
GCGAGCAAGCTCGGTGGCTGGGTGGGTTGGGGCGTTCCGCGCGCCCTTCATTGAAGCGGCGGTGGCCGGGCTGGGCGCCGGTAGTGGAAA
GCGACGGCGCGGCTGGAAAATGCCAGTCCATTCCCGAGGGGATAAGAAGGAGACCAACCATCACGATGAGATGGAGGTGGACTACGCCGA
AAATGAGGGGAGCAGCTCCGAGGACGAGGACACTGAGAGCTCGTCGGTCTCCGAGGATGGAGATAGCTCAGAAATGGATGATGAAGACTG
TGAAAGAAGAAGAATGGAATGTTTGGATGAAATGTCCAATCTTGAAAAACAGTTTACCGATCTCAAAGATCAACTTTATAAAGAACGATT
AAGTCAGGTGGATGCAAAACTACAAGAAGTCATAGCTGGAAAAGCACCAGAATACTTGGAACCGCTGGCAACTTTACAGGAAAATATGCA
AATTCGTACAAAGGTAGCAGGAATCTATAGAGAGCTCTGCTTAGAATCTGTAAAGAACAAATATGAATGTGAAATTCAAGCTTCTCGCCA
GCATTGTGAGGTTGCTGAGTCATTAGGAATCACAGAATTCCTACGGAAGAAAGAAATACACCCAGACAACCTTGGACCCAAGCACCTCAG
CCGAGACATGGATGGGGAGCAGCTAGAGGGAGCTAGCAGCGAGAAGAGGGAACGTGAGGCTGCGGAGGAGGGACTGGCCTCAGTGAAAAG
GCCCAGAAGAGAAGCCCTGTCCAACGATACCACTGAATCTCTTGCTGCCAACAGCAGAGGCCGGGAGAAGCCCAGGCCCTTGCATGCTTT
GGCCGCTGGTTTTTCCCCTCCAGTAAATGTGACTGTCTCTCCCCGTTCTGAAGAAAGCCATACAACGACGGTTTCTGGTGGCAATGGGAG
CGTGTTCCAGGCGGGCCCGCAGCTTCAGGCACTGGCTAACTTAGAAGCCAGGAGGGGGTCTATAGGTGCTGCTCTCTCATCCCGGGATGT
CAGTGGGCTGCCTGTTTATGCTCAGTCAGGAGAGCCTAGGAGGCTGACCCAGGCACAGGTGGCAGCGTTTCCTGGAGAGAATGCTTTGGA
ACACTCTTCAGACCAGGACACCTGGGACAGCCTGAGGAGCCCGGGTTTCTGCAGCCCTTTGTCATCTGGTGGTGGAGCAGAGTCCCTGCC
GCCTGGGGGGCCTGGACATGCAGAGGCAGGACACCTCGGCAAGGTTTGTGACTTCCACCTGAACCACCAGCAGCCCAGCCCCACCAGCGT
CCTGCCTACAGAGGTGGCAGCCCCTCCGCTTGAGAAAATTTTGTCTGTGGATAGCGTGGCAGTGGACTGTGCCTACAGGACTGTGCCCAA
GCCAGGGCCTCAGCCTGGCCCACATGGATCACTATTGACTGAAGGGTGTCTCAGAAGCCTTTCGGGGGACTTGAACCGGTTCCCCTGTGG
GATGGAGGTGCACTCTGGCCAGAGAGAACTGGAGAGCGTGGTTGCTGTCGGCGAAGCCATGGCTTTTGAAATTTCCAATGGGAGCCATGA
GTTACTGTCTCAGGGACAGAAGCAGATTTTTATTCAGACTTCCGATGGGCTTATCTTGTCCCCTCCAGGTACAATAGTGTCTCAGGAGGA
GGACATTGTCACAGTGACTGATGCAGAGGGGCGTGCCTGCGGATGGGCCCGCTAGAAGGAGTTCCTCTAGAAGCTGTGGAGTCGGTCGTC
ACCGTGGAGCCAGAGCCCTCACAGTGAAGTGGAGTCAGATCCTAGATTCGTCTGATTTTATCCAGAGAAGGTCTATGGCAAGCAATGTAT
ATTTTTCTAATGTGAATATTGCACAGATGAACCTTTTATTTATAAAGAATAATGTCTTTCTGC

>10318_10318_2_BRMS1L-ZNF839_BRMS1L_chr14_36304129_ENST00000216807_ZNF839_chr14_102805153_ENST00000442396_length(amino acids)=534AA_BP=160
MGAGSGKRRRGWKMPVHSRGDKKETNHHDEMEVDYAENEGSSSEDEDTESSSVSEDGDSSEMDDEDCERRRMECLDEMSNLEKQFTDLKD
QLYKERLSQVDAKLQEVIAGKAPEYLEPLATLQENMQIRTKVAGIYRELCLESVKNKYECEIQASRQHCEVAESLGITEFLRKKEIHPDN
LGPKHLSRDMDGEQLEGASSEKREREAAEEGLASVKRPRREALSNDTTESLAANSRGREKPRPLHALAAGFSPPVNVTVSPRSEESHTTT
VSGGNGSVFQAGPQLQALANLEARRGSIGAALSSRDVSGLPVYAQSGEPRRLTQAQVAAFPGENALEHSSDQDTWDSLRSPGFCSPLSSG
GGAESLPPGGPGHAEAGHLGKVCDFHLNHQQPSPTSVLPTEVAAPPLEKILSVDSVAVDCAYRTVPKPGPQPGPHGSLLTEGCLRSLSGD
LNRFPCGMEVHSGQRELESVVAVGEAMAFEISNGSHELLSQGQKQIFIQTSDGLILSPPGTIVSQEEDIVTVTDAEGRACGWAR

--------------------------------------------------------------
>10318_10318_3_BRMS1L-ZNF839_BRMS1L_chr14_36304129_ENST00000216807_ZNF839_chr14_102805153_ENST00000558850_length(transcript)=1950nt_BP=640nt
GGAAGGCCTCCGCCAATGGCAGAGCTCCCATCGCAGAGCCTGCGGGTTAGGTTGTGAGGCCCGGGCCGGGGGCGGGGAGGAGCCAAGGGG
GCGAGCAAGCTCGGTGGCTGGGTGGGTTGGGGCGTTCCGCGCGCCCTTCATTGAAGCGGCGGTGGCCGGGCTGGGCGCCGGTAGTGGAAA
GCGACGGCGCGGCTGGAAAATGCCAGTCCATTCCCGAGGGGATAAGAAGGAGACCAACCATCACGATGAGATGGAGGTGGACTACGCCGA
AAATGAGGGGAGCAGCTCCGAGGACGAGGACACTGAGAGCTCGTCGGTCTCCGAGGATGGAGATAGCTCAGAAATGGATGATGAAGACTG
TGAAAGAAGAAGAATGGAATGTTTGGATGAAATGTCCAATCTTGAAAAACAGTTTACCGATCTCAAAGATCAACTTTATAAAGAACGATT
AAGTCAGGTGGATGCAAAACTACAAGAAGTCATAGCTGGAAAAGCACCAGAATACTTGGAACCGCTGGCAACTTTACAGGAAAATATGCA
AATTCGTACAAAGGTAGCAGGAATCTATAGAGAGCTCTGCTTAGAATCTGTAAAGAACAAATATGAATGTGAAATTCAAGCTTCTCGCCA
GCATTGTGAGGTTGCTGAGTCATTAGGAATCACAGAATTCCTACGGAAGAAAGAAATACACCCAGACAACCTTGGACCCAAGCACCTCAG
CCGAGACATGGATGGGGAGCAGCTAGAGGGAGCTAGCAGCGAGAAGAGGGAACGTGAGGCTGCGGAGGAGGGACTGGCCTCAGTGAAAAG
GCCCAGAAGAGAAGCCCTGTCCAACGATACCACTGAATCTCTTGCTGCCAACAGCAGAGGCCGGGAGAAGCCCAGGCCCTTGCATGCTTT
GGCCGCTGGTTTTTCCCCTCCAGTAAATGTGACTGTCTCTCCCCGTTCTGAAGAAAGCCATACAACGACGGTTTCTGGTGGCAATGGGAG
CGTGTTCCAGGCGGGCCCGCAGCTTCAGGCACTGGCTAACTTAGAAGCCAGGAGGGGGTCTATAGGTGCTGCTCTCTCATCCCGGGATGT
CAGTGGGCTGCCTGTTTATGCTCAGTCAGGAGAGCCTAGGAGGCTGACCCAGGCACAGGTGGCAGCGTTTCCTGGAGAGAATGCTTTGGA
ACACTCTTCAGACCAGGACACCTGGGACAGCCTGAGGAGCCCGGGTTTCTGCAGCCCTTTGTCATCTGGTGGTGGAGCAGAGTCCCTGCC
GCCTGGGGGGCCTGGACATGCAGAGGCAGGACACCTCGGCAAGGTTTGTGACTTCCACCTGAACCACCAGCAGCCCAGCCCCACCAGCGT
CCTGCCTACAGAGGTGGCAGCCCCTCCGCTTGAGAAAATTTTGTCTGTGGATAGCGTGGCAGTGGACTGTGCCTACAGGACTGTGCCCAA
GCCAGGGCCTCAGCCTGGCCCACATGGATCACTATTGACTGAAGGGTGTCTCAGAAGCCTTTCGGGGGACTTGAACCGGTTCCCCTGTGG
GATGGAGGTGCACTCTGGCCAGAGAGAACTGGAGAGCGTGGTTGCTGTCGGCGAAGCCATGGCTTTTGAAATTTCCAATGGGAGCCATGA
GTTACTGTCTCAGGGACAGAAGCAGATTTTTATTCAGACTTCCGATGGGCTTATCTTGTCCCCTCCAGGTACAATAGTGTCTCAGGAGGA
GGACATTGTCACAGTGACTGATGCAGAGGGGCGTGCCTGCGGATGGGCCCGCTAGAAGGAGTTCCTCTAGAAGCTGTGGAGTCGGTCGTC
ACCGTGGAGCCAGAGCCCTCACAGTGAAGTGGAGTCAGATCCTAGATTCGTCTGATTTTATCCAGAGAAGGTCTATGGCAAGCAATGTAT
ATTTTTCTAATGTGAATATTGCACAGATGAACCTTTTATTTATAAAGAATAATGTCTTTC

>10318_10318_3_BRMS1L-ZNF839_BRMS1L_chr14_36304129_ENST00000216807_ZNF839_chr14_102805153_ENST00000558850_length(amino acids)=534AA_BP=160
MGAGSGKRRRGWKMPVHSRGDKKETNHHDEMEVDYAENEGSSSEDEDTESSSVSEDGDSSEMDDEDCERRRMECLDEMSNLEKQFTDLKD
QLYKERLSQVDAKLQEVIAGKAPEYLEPLATLQENMQIRTKVAGIYRELCLESVKNKYECEIQASRQHCEVAESLGITEFLRKKEIHPDN
LGPKHLSRDMDGEQLEGASSEKREREAAEEGLASVKRPRREALSNDTTESLAANSRGREKPRPLHALAAGFSPPVNVTVSPRSEESHTTT
VSGGNGSVFQAGPQLQALANLEARRGSIGAALSSRDVSGLPVYAQSGEPRRLTQAQVAAFPGENALEHSSDQDTWDSLRSPGFCSPLSSG
GGAESLPPGGPGHAEAGHLGKVCDFHLNHQQPSPTSVLPTEVAAPPLEKILSVDSVAVDCAYRTVPKPGPQPGPHGSLLTEGCLRSLSGD
LNRFPCGMEVHSGQRELESVVAVGEAMAFEISNGSHELLSQGQKQIFIQTSDGLILSPPGTIVSQEEDIVTVTDAEGRACGWAR

--------------------------------------------------------------
>10318_10318_4_BRMS1L-ZNF839_BRMS1L_chr14_36304129_ENST00000216807_ZNF839_chr14_102805153_ENST00000559185_length(transcript)=1953nt_BP=640nt
GGAAGGCCTCCGCCAATGGCAGAGCTCCCATCGCAGAGCCTGCGGGTTAGGTTGTGAGGCCCGGGCCGGGGGCGGGGAGGAGCCAAGGGG
GCGAGCAAGCTCGGTGGCTGGGTGGGTTGGGGCGTTCCGCGCGCCCTTCATTGAAGCGGCGGTGGCCGGGCTGGGCGCCGGTAGTGGAAA
GCGACGGCGCGGCTGGAAAATGCCAGTCCATTCCCGAGGGGATAAGAAGGAGACCAACCATCACGATGAGATGGAGGTGGACTACGCCGA
AAATGAGGGGAGCAGCTCCGAGGACGAGGACACTGAGAGCTCGTCGGTCTCCGAGGATGGAGATAGCTCAGAAATGGATGATGAAGACTG
TGAAAGAAGAAGAATGGAATGTTTGGATGAAATGTCCAATCTTGAAAAACAGTTTACCGATCTCAAAGATCAACTTTATAAAGAACGATT
AAGTCAGGTGGATGCAAAACTACAAGAAGTCATAGCTGGAAAAGCACCAGAATACTTGGAACCGCTGGCAACTTTACAGGAAAATATGCA
AATTCGTACAAAGGTAGCAGGAATCTATAGAGAGCTCTGCTTAGAATCTGTAAAGAACAAATATGAATGTGAAATTCAAGCTTCTCGCCA
GCATTGTGAGGTTGCTGAGTCATTAGGAATCACAGAATTCCTACGGAAGAAAGAAATACACCCAGACAACCTTGGACCCAAGCACCTCAG
CCGAGACATGGATGGGGAGCAGCTAGAGGGAGCTAGCAGCGAGAAGAGGGAACGTGAGGCTGCGGAGGAGGGACTGGCCTCAGTGAAAAG
GCCCAGAAGAGAAGCCCTGTCCAACGATACCACTGAATCTCTTGCTGCCAACAGCAGAGGCCGGGAGAAGCCCAGGCCCTTGCATGCTTT
GGCCGCTGGTTTTTCCCCTCCAGTAAATGTGACTGTCTCTCCCCGTTCTGAAGAAAGCCATACAACGACGGTTTCTGGTGGCAATGGGAG
CGTGTTCCAGGCGGGCCCGCAGCTTCAGGCACTGGCTAACTTAGAAGCCAGGAGGGGGTCTATAGGTGCTGCTCTCTCATCCCGGGATGT
CAGTGGGCTGCCTGTTTATGCTCAGTCAGGAGAGCCTAGGAGGCTGACCCAGGCACAGGTGGCAGCGTTTCCTGGAGAGAATGCTTTGGA
ACACTCTTCAGACCAGGACACCTGGGACAGCCTGAGGAGCCCGGGTTTCTGCAGCCCTTTGTCATCTGGTGGTGGAGCAGAGTCCCTGCC
GCCTGGGGGGCCTGGACATGCAGAGGCAGGACACCTCGGCAAGGTTTGTGACTTCCACCTGAACCACCAGCAGCCCAGCCCCACCAGCGT
CCTGCCTACAGAGGTGGCAGCCCCTCCGCTTGAGAAAATTTTGTCTGTGGATAGCGTGGCAGTGGACTGTGCCTACAGGACTGTGCCCAA
GCCAGGGCCTCAGCCTGGCCCACATGGATCACTATTGACTGAAGGGTGTCTCAGAAGCCTTTCGGGGGACTTGAACCGGTTCCCCTGTGG
GATGGAGGTGCACTCTGGCCAGAGAGAACTGGAGAGCGTGGTTGCTGTCGGCGAAGCCATGGCTTTTGAAATTTCCAATGGGAGCCATGA
GTTACTGTCTCAGGGACAGAAGCAGATTTTTATTCAGACTTCCGATGGGCTTATCTTGTCCCCTCCAGGTACAATAGTGTCTCAGGAGGA
GGACATTGTCACAGTGACTGATGCAGAGGGGCGTGCCTGCGGATGGGCCCGCTAGAAGGAGTTCCTCTAGAAGCTGTGGAGTCGGTCGTC
ACCGTGGAGCCAGAGCCCTCACAGTGAAGTGGAGTCAGATCCTAGATTCGTCTGATTTTATCCAGAGAAGGTCTATGGCAAGCAATGTAT
ATTTTTCTAATGTGAATATTGCACAGATGAACCTTTTATTTATAAAGAATAATGTCTTTCTGC

>10318_10318_4_BRMS1L-ZNF839_BRMS1L_chr14_36304129_ENST00000216807_ZNF839_chr14_102805153_ENST00000559185_length(amino acids)=534AA_BP=160
MGAGSGKRRRGWKMPVHSRGDKKETNHHDEMEVDYAENEGSSSEDEDTESSSVSEDGDSSEMDDEDCERRRMECLDEMSNLEKQFTDLKD
QLYKERLSQVDAKLQEVIAGKAPEYLEPLATLQENMQIRTKVAGIYRELCLESVKNKYECEIQASRQHCEVAESLGITEFLRKKEIHPDN
LGPKHLSRDMDGEQLEGASSEKREREAAEEGLASVKRPRREALSNDTTESLAANSRGREKPRPLHALAAGFSPPVNVTVSPRSEESHTTT
VSGGNGSVFQAGPQLQALANLEARRGSIGAALSSRDVSGLPVYAQSGEPRRLTQAQVAAFPGENALEHSSDQDTWDSLRSPGFCSPLSSG
GGAESLPPGGPGHAEAGHLGKVCDFHLNHQQPSPTSVLPTEVAAPPLEKILSVDSVAVDCAYRTVPKPGPQPGPHGSLLTEGCLRSLSGD
LNRFPCGMEVHSGQRELESVVAVGEAMAFEISNGSHELLSQGQKQIFIQTSDGLILSPPGTIVSQEEDIVTVTDAEGRACGWAR

--------------------------------------------------------------
>10318_10318_5_BRMS1L-ZNF839_BRMS1L_chr14_36304129_ENST00000543183_ZNF839_chr14_102805153_ENST00000262236_length(transcript)=2289nt_BP=630nt
GTTCCGCGCGCCCTTCATTGAAGCGGCGGTGGCCGGGCTGGGCGCCGGTAGTGGAAAGCGACGGCGCGGCTGGAAAATGCCAGTCCATTC
CCGAGGGGATAAGAAGGAGACCAACCATCACGATGAGATGGAGGTGGACTACGCCGAAAATGAGGGGAGCAGCTCCGAGGACGAGGACAC
TGAGAGCTCGTCGGTCTCCGAGGATGGAGATAGCTCAGTTTGACTTTTATTTGATGAAGATCAAGATGCAGATCATTTTGTGCTTCAGTT
ATTTTGATGAATGAATATATGTGATATGAACATAGAAAATGTGGACTATAGGACAGACCTGAAATGGATGATGAAGACTGTGAAAGAAGA
AGAATGGAATGTTTGGATGAAATGTCCAATCTTGAAAAACAGTTTACCGATCTCAAAGATCAACTTTATAAAGAACGATTAAGTCAGGTG
GATGCAAAACTACAAGAAGTCATAGCTGGAAAAGCACCAGAATACTTGGAACCGCTGGCAACTTTACAGGAAAATATGCAAATTCGTACA
AAGGTAGCAGGAATCTATAGAGAGCTCTGCTTAGAATCTGTAAAGAACAAATATGAATGTGAAATTCAAGCTTCTCGCCAGCATTGTGAG
GTTGCTGAGTCATTAGGAATCACAGAATTCCTACGGAAGAAAGAAATACACCCAGACAACCTTGGACCCAAGCACCTCAGCCGAGACATG
GATGGGGAGCAGCTAGAGGGAGCTAGCAGCGAGAAGAGGGAACGTGAGGCTGCGGAGGAGGGACTGGCCTCAGTGAAAAGGCCCAGAAGA
GAAGCCCTGTCCAACGATACCACTGAATCTCTTGCTGCCAACAGCAGAGGCCGGGAGAAGCCCAGGCCCTTGCATGCTTTGGCCGCTGGT
GAGGGTTTTTCCCCTCCAGTAAATGTGACTGTCTCTCCCCGTTCTGAAGAAAGCCATACAACGACGGTTTCTGGTGGCAATGGGAGCGTG
TTCCAGGCGGGCCCGCAGCTTCAGGCACTGGCTAACTTAGAAGCCAGGAGGGGGTCTATAGGTGCTGCTCTCTCATCCCGGGATGTCAGT
GGGCTGCCTGTTTATGCTCAGTCAGGAGAGCCTAGGAGGCTGACCCAGGCACAGGTGGCAGCGTTTCCTGGAGAGAATGCTTTGGAACAC
TCTTCAGACCAGGACACCTGGGACAGCCTGAGGAGCCCGGGTTTCTGCAGCCCTTTGTCATCTGGTGGTGGAGCAGAGTCCCTGCCGCCT
GGGGGGCCTGGACATGCAGAGGCAGGACACCTCGGCAAGGTTTGTGACTTCCACCTGAACCACCAGCAGCCCAGCCCCACCAGCGTCCTG
CCTACAGAGGTGGCAGCCCCTCCGCTTGAGAAAATTTTGTCTGTGGATAGCGTGGCAGTGGACTGTGCCTACAGGACTGTGCCCAAGCCA
GGGCCTCAGCCTGGCCCACATGGATCACTATTGACTGAAGGGTGTCTCAGAAGCCTTTCGGGGGACTTGAACCGGTTCCCCTGTGGGATG
GAGGTGCACTCTGGCCAGAGAGAACTGGAGAGCGTGGTTGCTGTCGGCGAAGCCATGGCTTTTGAAATTTCCAATGGGAGCCATGAGTTA
CTGTCTCAGGGACAGAAGCAGATTTTTATTCAGACTTCCGATGGGCTTATCTTGTCCCCTCCAGGTACAATAGTGTCTCAGGAGGAGGAC
ATTGTCACAGTGACTGATGCAGAGGGGCGTGCCTGCGGATGGGCCCGCTAGAAGGAGTTCCTCTAGAAGCTGTGGAGTCGGTCGTCACCG
TGGAGCCAGAGCCCTCACAGTGAAGTGGAGTCAGATCCTAGATTCGTCTGATTTTATCCAGAGAAGGTCTATGGCAAGCAATGTATATTT
TTCTAATGTGAATATTGCACAGATGAACCTTTTATTTATAAAGAATAATGTCTTTCTGCCCTGCTGTCTACATTTTTCTATGGAGCTTGT
CATAATAATAGCAGATATTACCTGATCAGGAATCCCTGTGGCGCGTCTGACGCTCATGAGTTTTTCATGATGGTGATGAGTAGCACTGCA
CTGTCACCTGATGATTGGCCCTGCTCCGTTTCCCTTCTCTCCTGGGAGATATGCTGCTTTTCCACCAGACTTGCTCCATACTAGAAGCTT
CTTTTGGGTTCAATTAAAAAGAAAATAAGCTAGTCATTCTGGGCAGCATTTTATTGATAGAAGGGGGAAAAAGTCATTTCTACTTGCATG
ATTTTTTAAATTAAATTAAATTAAATTAATTTAATTATT

>10318_10318_5_BRMS1L-ZNF839_BRMS1L_chr14_36304129_ENST00000543183_ZNF839_chr14_102805153_ENST00000262236_length(amino acids)=475AA_BP=99
MDDEDCERRRMECLDEMSNLEKQFTDLKDQLYKERLSQVDAKLQEVIAGKAPEYLEPLATLQENMQIRTKVAGIYRELCLESVKNKYECE
IQASRQHCEVAESLGITEFLRKKEIHPDNLGPKHLSRDMDGEQLEGASSEKREREAAEEGLASVKRPRREALSNDTTESLAANSRGREKP
RPLHALAAGEGFSPPVNVTVSPRSEESHTTTVSGGNGSVFQAGPQLQALANLEARRGSIGAALSSRDVSGLPVYAQSGEPRRLTQAQVAA
FPGENALEHSSDQDTWDSLRSPGFCSPLSSGGGAESLPPGGPGHAEAGHLGKVCDFHLNHQQPSPTSVLPTEVAAPPLEKILSVDSVAVD
CAYRTVPKPGPQPGPHGSLLTEGCLRSLSGDLNRFPCGMEVHSGQRELESVVAVGEAMAFEISNGSHELLSQGQKQIFIQTSDGLILSPP
GTIVSQEEDIVTVTDAEGRACGWAR

--------------------------------------------------------------
>10318_10318_6_BRMS1L-ZNF839_BRMS1L_chr14_36304129_ENST00000543183_ZNF839_chr14_102805153_ENST00000442396_length(transcript)=1943nt_BP=630nt
GTTCCGCGCGCCCTTCATTGAAGCGGCGGTGGCCGGGCTGGGCGCCGGTAGTGGAAAGCGACGGCGCGGCTGGAAAATGCCAGTCCATTC
CCGAGGGGATAAGAAGGAGACCAACCATCACGATGAGATGGAGGTGGACTACGCCGAAAATGAGGGGAGCAGCTCCGAGGACGAGGACAC
TGAGAGCTCGTCGGTCTCCGAGGATGGAGATAGCTCAGTTTGACTTTTATTTGATGAAGATCAAGATGCAGATCATTTTGTGCTTCAGTT
ATTTTGATGAATGAATATATGTGATATGAACATAGAAAATGTGGACTATAGGACAGACCTGAAATGGATGATGAAGACTGTGAAAGAAGA
AGAATGGAATGTTTGGATGAAATGTCCAATCTTGAAAAACAGTTTACCGATCTCAAAGATCAACTTTATAAAGAACGATTAAGTCAGGTG
GATGCAAAACTACAAGAAGTCATAGCTGGAAAAGCACCAGAATACTTGGAACCGCTGGCAACTTTACAGGAAAATATGCAAATTCGTACA
AAGGTAGCAGGAATCTATAGAGAGCTCTGCTTAGAATCTGTAAAGAACAAATATGAATGTGAAATTCAAGCTTCTCGCCAGCATTGTGAG
GTTGCTGAGTCATTAGGAATCACAGAATTCCTACGGAAGAAAGAAATACACCCAGACAACCTTGGACCCAAGCACCTCAGCCGAGACATG
GATGGGGAGCAGCTAGAGGGAGCTAGCAGCGAGAAGAGGGAACGTGAGGCTGCGGAGGAGGGACTGGCCTCAGTGAAAAGGCCCAGAAGA
GAAGCCCTGTCCAACGATACCACTGAATCTCTTGCTGCCAACAGCAGAGGCCGGGAGAAGCCCAGGCCCTTGCATGCTTTGGCCGCTGGT
TTTTCCCCTCCAGTAAATGTGACTGTCTCTCCCCGTTCTGAAGAAAGCCATACAACGACGGTTTCTGGTGGCAATGGGAGCGTGTTCCAG
GCGGGCCCGCAGCTTCAGGCACTGGCTAACTTAGAAGCCAGGAGGGGGTCTATAGGTGCTGCTCTCTCATCCCGGGATGTCAGTGGGCTG
CCTGTTTATGCTCAGTCAGGAGAGCCTAGGAGGCTGACCCAGGCACAGGTGGCAGCGTTTCCTGGAGAGAATGCTTTGGAACACTCTTCA
GACCAGGACACCTGGGACAGCCTGAGGAGCCCGGGTTTCTGCAGCCCTTTGTCATCTGGTGGTGGAGCAGAGTCCCTGCCGCCTGGGGGG
CCTGGACATGCAGAGGCAGGACACCTCGGCAAGGTTTGTGACTTCCACCTGAACCACCAGCAGCCCAGCCCCACCAGCGTCCTGCCTACA
GAGGTGGCAGCCCCTCCGCTTGAGAAAATTTTGTCTGTGGATAGCGTGGCAGTGGACTGTGCCTACAGGACTGTGCCCAAGCCAGGGCCT
CAGCCTGGCCCACATGGATCACTATTGACTGAAGGGTGTCTCAGAAGCCTTTCGGGGGACTTGAACCGGTTCCCCTGTGGGATGGAGGTG
CACTCTGGCCAGAGAGAACTGGAGAGCGTGGTTGCTGTCGGCGAAGCCATGGCTTTTGAAATTTCCAATGGGAGCCATGAGTTACTGTCT
CAGGGACAGAAGCAGATTTTTATTCAGACTTCCGATGGGCTTATCTTGTCCCCTCCAGGTACAATAGTGTCTCAGGAGGAGGACATTGTC
ACAGTGACTGATGCAGAGGGGCGTGCCTGCGGATGGGCCCGCTAGAAGGAGTTCCTCTAGAAGCTGTGGAGTCGGTCGTCACCGTGGAGC
CAGAGCCCTCACAGTGAAGTGGAGTCAGATCCTAGATTCGTCTGATTTTATCCAGAGAAGGTCTATGGCAAGCAATGTATATTTTTCTAA
TGTGAATATTGCACAGATGAACCTTTTATTTATAAAGAATAATGTCTTTCTGC

>10318_10318_6_BRMS1L-ZNF839_BRMS1L_chr14_36304129_ENST00000543183_ZNF839_chr14_102805153_ENST00000442396_length(amino acids)=473AA_BP=99
MDDEDCERRRMECLDEMSNLEKQFTDLKDQLYKERLSQVDAKLQEVIAGKAPEYLEPLATLQENMQIRTKVAGIYRELCLESVKNKYECE
IQASRQHCEVAESLGITEFLRKKEIHPDNLGPKHLSRDMDGEQLEGASSEKREREAAEEGLASVKRPRREALSNDTTESLAANSRGREKP
RPLHALAAGFSPPVNVTVSPRSEESHTTTVSGGNGSVFQAGPQLQALANLEARRGSIGAALSSRDVSGLPVYAQSGEPRRLTQAQVAAFP
GENALEHSSDQDTWDSLRSPGFCSPLSSGGGAESLPPGGPGHAEAGHLGKVCDFHLNHQQPSPTSVLPTEVAAPPLEKILSVDSVAVDCA
YRTVPKPGPQPGPHGSLLTEGCLRSLSGDLNRFPCGMEVHSGQRELESVVAVGEAMAFEISNGSHELLSQGQKQIFIQTSDGLILSPPGT
IVSQEEDIVTVTDAEGRACGWAR

--------------------------------------------------------------
>10318_10318_7_BRMS1L-ZNF839_BRMS1L_chr14_36304129_ENST00000543183_ZNF839_chr14_102805153_ENST00000558850_length(transcript)=1940nt_BP=630nt
GTTCCGCGCGCCCTTCATTGAAGCGGCGGTGGCCGGGCTGGGCGCCGGTAGTGGAAAGCGACGGCGCGGCTGGAAAATGCCAGTCCATTC
CCGAGGGGATAAGAAGGAGACCAACCATCACGATGAGATGGAGGTGGACTACGCCGAAAATGAGGGGAGCAGCTCCGAGGACGAGGACAC
TGAGAGCTCGTCGGTCTCCGAGGATGGAGATAGCTCAGTTTGACTTTTATTTGATGAAGATCAAGATGCAGATCATTTTGTGCTTCAGTT
ATTTTGATGAATGAATATATGTGATATGAACATAGAAAATGTGGACTATAGGACAGACCTGAAATGGATGATGAAGACTGTGAAAGAAGA
AGAATGGAATGTTTGGATGAAATGTCCAATCTTGAAAAACAGTTTACCGATCTCAAAGATCAACTTTATAAAGAACGATTAAGTCAGGTG
GATGCAAAACTACAAGAAGTCATAGCTGGAAAAGCACCAGAATACTTGGAACCGCTGGCAACTTTACAGGAAAATATGCAAATTCGTACA
AAGGTAGCAGGAATCTATAGAGAGCTCTGCTTAGAATCTGTAAAGAACAAATATGAATGTGAAATTCAAGCTTCTCGCCAGCATTGTGAG
GTTGCTGAGTCATTAGGAATCACAGAATTCCTACGGAAGAAAGAAATACACCCAGACAACCTTGGACCCAAGCACCTCAGCCGAGACATG
GATGGGGAGCAGCTAGAGGGAGCTAGCAGCGAGAAGAGGGAACGTGAGGCTGCGGAGGAGGGACTGGCCTCAGTGAAAAGGCCCAGAAGA
GAAGCCCTGTCCAACGATACCACTGAATCTCTTGCTGCCAACAGCAGAGGCCGGGAGAAGCCCAGGCCCTTGCATGCTTTGGCCGCTGGT
TTTTCCCCTCCAGTAAATGTGACTGTCTCTCCCCGTTCTGAAGAAAGCCATACAACGACGGTTTCTGGTGGCAATGGGAGCGTGTTCCAG
GCGGGCCCGCAGCTTCAGGCACTGGCTAACTTAGAAGCCAGGAGGGGGTCTATAGGTGCTGCTCTCTCATCCCGGGATGTCAGTGGGCTG
CCTGTTTATGCTCAGTCAGGAGAGCCTAGGAGGCTGACCCAGGCACAGGTGGCAGCGTTTCCTGGAGAGAATGCTTTGGAACACTCTTCA
GACCAGGACACCTGGGACAGCCTGAGGAGCCCGGGTTTCTGCAGCCCTTTGTCATCTGGTGGTGGAGCAGAGTCCCTGCCGCCTGGGGGG
CCTGGACATGCAGAGGCAGGACACCTCGGCAAGGTTTGTGACTTCCACCTGAACCACCAGCAGCCCAGCCCCACCAGCGTCCTGCCTACA
GAGGTGGCAGCCCCTCCGCTTGAGAAAATTTTGTCTGTGGATAGCGTGGCAGTGGACTGTGCCTACAGGACTGTGCCCAAGCCAGGGCCT
CAGCCTGGCCCACATGGATCACTATTGACTGAAGGGTGTCTCAGAAGCCTTTCGGGGGACTTGAACCGGTTCCCCTGTGGGATGGAGGTG
CACTCTGGCCAGAGAGAACTGGAGAGCGTGGTTGCTGTCGGCGAAGCCATGGCTTTTGAAATTTCCAATGGGAGCCATGAGTTACTGTCT
CAGGGACAGAAGCAGATTTTTATTCAGACTTCCGATGGGCTTATCTTGTCCCCTCCAGGTACAATAGTGTCTCAGGAGGAGGACATTGTC
ACAGTGACTGATGCAGAGGGGCGTGCCTGCGGATGGGCCCGCTAGAAGGAGTTCCTCTAGAAGCTGTGGAGTCGGTCGTCACCGTGGAGC
CAGAGCCCTCACAGTGAAGTGGAGTCAGATCCTAGATTCGTCTGATTTTATCCAGAGAAGGTCTATGGCAAGCAATGTATATTTTTCTAA
TGTGAATATTGCACAGATGAACCTTTTATTTATAAAGAATAATGTCTTTC

>10318_10318_7_BRMS1L-ZNF839_BRMS1L_chr14_36304129_ENST00000543183_ZNF839_chr14_102805153_ENST00000558850_length(amino acids)=473AA_BP=99
MDDEDCERRRMECLDEMSNLEKQFTDLKDQLYKERLSQVDAKLQEVIAGKAPEYLEPLATLQENMQIRTKVAGIYRELCLESVKNKYECE
IQASRQHCEVAESLGITEFLRKKEIHPDNLGPKHLSRDMDGEQLEGASSEKREREAAEEGLASVKRPRREALSNDTTESLAANSRGREKP
RPLHALAAGFSPPVNVTVSPRSEESHTTTVSGGNGSVFQAGPQLQALANLEARRGSIGAALSSRDVSGLPVYAQSGEPRRLTQAQVAAFP
GENALEHSSDQDTWDSLRSPGFCSPLSSGGGAESLPPGGPGHAEAGHLGKVCDFHLNHQQPSPTSVLPTEVAAPPLEKILSVDSVAVDCA
YRTVPKPGPQPGPHGSLLTEGCLRSLSGDLNRFPCGMEVHSGQRELESVVAVGEAMAFEISNGSHELLSQGQKQIFIQTSDGLILSPPGT
IVSQEEDIVTVTDAEGRACGWAR

--------------------------------------------------------------
>10318_10318_8_BRMS1L-ZNF839_BRMS1L_chr14_36304129_ENST00000543183_ZNF839_chr14_102805153_ENST00000559185_length(transcript)=1943nt_BP=630nt
GTTCCGCGCGCCCTTCATTGAAGCGGCGGTGGCCGGGCTGGGCGCCGGTAGTGGAAAGCGACGGCGCGGCTGGAAAATGCCAGTCCATTC
CCGAGGGGATAAGAAGGAGACCAACCATCACGATGAGATGGAGGTGGACTACGCCGAAAATGAGGGGAGCAGCTCCGAGGACGAGGACAC
TGAGAGCTCGTCGGTCTCCGAGGATGGAGATAGCTCAGTTTGACTTTTATTTGATGAAGATCAAGATGCAGATCATTTTGTGCTTCAGTT
ATTTTGATGAATGAATATATGTGATATGAACATAGAAAATGTGGACTATAGGACAGACCTGAAATGGATGATGAAGACTGTGAAAGAAGA
AGAATGGAATGTTTGGATGAAATGTCCAATCTTGAAAAACAGTTTACCGATCTCAAAGATCAACTTTATAAAGAACGATTAAGTCAGGTG
GATGCAAAACTACAAGAAGTCATAGCTGGAAAAGCACCAGAATACTTGGAACCGCTGGCAACTTTACAGGAAAATATGCAAATTCGTACA
AAGGTAGCAGGAATCTATAGAGAGCTCTGCTTAGAATCTGTAAAGAACAAATATGAATGTGAAATTCAAGCTTCTCGCCAGCATTGTGAG
GTTGCTGAGTCATTAGGAATCACAGAATTCCTACGGAAGAAAGAAATACACCCAGACAACCTTGGACCCAAGCACCTCAGCCGAGACATG
GATGGGGAGCAGCTAGAGGGAGCTAGCAGCGAGAAGAGGGAACGTGAGGCTGCGGAGGAGGGACTGGCCTCAGTGAAAAGGCCCAGAAGA
GAAGCCCTGTCCAACGATACCACTGAATCTCTTGCTGCCAACAGCAGAGGCCGGGAGAAGCCCAGGCCCTTGCATGCTTTGGCCGCTGGT
TTTTCCCCTCCAGTAAATGTGACTGTCTCTCCCCGTTCTGAAGAAAGCCATACAACGACGGTTTCTGGTGGCAATGGGAGCGTGTTCCAG
GCGGGCCCGCAGCTTCAGGCACTGGCTAACTTAGAAGCCAGGAGGGGGTCTATAGGTGCTGCTCTCTCATCCCGGGATGTCAGTGGGCTG
CCTGTTTATGCTCAGTCAGGAGAGCCTAGGAGGCTGACCCAGGCACAGGTGGCAGCGTTTCCTGGAGAGAATGCTTTGGAACACTCTTCA
GACCAGGACACCTGGGACAGCCTGAGGAGCCCGGGTTTCTGCAGCCCTTTGTCATCTGGTGGTGGAGCAGAGTCCCTGCCGCCTGGGGGG
CCTGGACATGCAGAGGCAGGACACCTCGGCAAGGTTTGTGACTTCCACCTGAACCACCAGCAGCCCAGCCCCACCAGCGTCCTGCCTACA
GAGGTGGCAGCCCCTCCGCTTGAGAAAATTTTGTCTGTGGATAGCGTGGCAGTGGACTGTGCCTACAGGACTGTGCCCAAGCCAGGGCCT
CAGCCTGGCCCACATGGATCACTATTGACTGAAGGGTGTCTCAGAAGCCTTTCGGGGGACTTGAACCGGTTCCCCTGTGGGATGGAGGTG
CACTCTGGCCAGAGAGAACTGGAGAGCGTGGTTGCTGTCGGCGAAGCCATGGCTTTTGAAATTTCCAATGGGAGCCATGAGTTACTGTCT
CAGGGACAGAAGCAGATTTTTATTCAGACTTCCGATGGGCTTATCTTGTCCCCTCCAGGTACAATAGTGTCTCAGGAGGAGGACATTGTC
ACAGTGACTGATGCAGAGGGGCGTGCCTGCGGATGGGCCCGCTAGAAGGAGTTCCTCTAGAAGCTGTGGAGTCGGTCGTCACCGTGGAGC
CAGAGCCCTCACAGTGAAGTGGAGTCAGATCCTAGATTCGTCTGATTTTATCCAGAGAAGGTCTATGGCAAGCAATGTATATTTTTCTAA
TGTGAATATTGCACAGATGAACCTTTTATTTATAAAGAATAATGTCTTTCTGC

>10318_10318_8_BRMS1L-ZNF839_BRMS1L_chr14_36304129_ENST00000543183_ZNF839_chr14_102805153_ENST00000559185_length(amino acids)=473AA_BP=99
MDDEDCERRRMECLDEMSNLEKQFTDLKDQLYKERLSQVDAKLQEVIAGKAPEYLEPLATLQENMQIRTKVAGIYRELCLESVKNKYECE
IQASRQHCEVAESLGITEFLRKKEIHPDNLGPKHLSRDMDGEQLEGASSEKREREAAEEGLASVKRPRREALSNDTTESLAANSRGREKP
RPLHALAAGFSPPVNVTVSPRSEESHTTTVSGGNGSVFQAGPQLQALANLEARRGSIGAALSSRDVSGLPVYAQSGEPRRLTQAQVAAFP
GENALEHSSDQDTWDSLRSPGFCSPLSSGGGAESLPPGGPGHAEAGHLGKVCDFHLNHQQPSPTSVLPTEVAAPPLEKILSVDSVAVDCA
YRTVPKPGPQPGPHGSLLTEGCLRSLSGDLNRFPCGMEVHSGQRELESVVAVGEAMAFEISNGSHELLSQGQKQIFIQTSDGLILSPPGT
IVSQEEDIVTVTDAEGRACGWAR

--------------------------------------------------------------

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Fusion Gene PPI Analysis for BRMS1L-ZNF839


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for BRMS1L-ZNF839


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for BRMS1L-ZNF839


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource